LOCUS       DACBZK010000001       155381 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.001, whole genome shotgun sequence.
ACCESSION   DACBZK010000001 DACBZK010000000
VERSION     DACBZK010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 155381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 155381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..155381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.001"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(5..2191)
                     /locus_tag="IVD66_000001"
     CDS             complement(5..2191)
                     /locus_tag="IVD66_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAP6144259.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNISVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            2409..3092
                     /locus_tag="IVD66_000002"
     CDS             2409..3092
                     /locus_tag="IVD66_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HAP6144260.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            complement(3173..3892)
                     /locus_tag="IVD66_000003"
     CDS             complement(3173..3892)
                     /locus_tag="IVD66_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAP6144261.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(4204..4410)
                     /locus_tag="IVD66_000004"
     CDS             complement(4204..4410)
                     /locus_tag="IVD66_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144262.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            4655..5257
                     /locus_tag="IVD66_000005"
     CDS             4655..5257
                     /locus_tag="IVD66_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory regulator AgrB"
                     /protein_id="HAP6144263.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            5398..6678
                     /locus_tag="IVD66_000006"
     CDS             5398..6678
                     /locus_tag="IVD66_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP6144264.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            6691..7419
                     /locus_tag="IVD66_000007"
     CDS             6691..7419
                     /locus_tag="IVD66_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6144265.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(7488..9011)
                     /locus_tag="IVD66_000008"
     CDS             complement(7488..9011)
                     /locus_tag="IVD66_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAP6144266.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            9263..10444
                     /locus_tag="IVD66_000009"
     CDS             9263..10444
                     /locus_tag="IVD66_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP6144267.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(10504..12132)
                     /gene="treC"
                     /locus_tag="IVD66_000010"
     CDS             complement(10504..12132)
                     /gene="treC"
                     /locus_tag="IVD66_000010"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HAP6144268.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(12583..15294)
                     /locus_tag="IVD66_000011"
     CDS             complement(12583..15294)
                     /locus_tag="IVD66_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAP6144269.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGTIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(15304..16005)
                     /locus_tag="IVD66_000012"
     CDS             complement(15304..16005)
                     /locus_tag="IVD66_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6144270.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            16191..16790
                     /locus_tag="IVD66_000013"
     CDS             16191..16790
                     /locus_tag="IVD66_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP6144271.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            16871..17884
                     /locus_tag="IVD66_000014"
     CDS             16871..17884
                     /locus_tag="IVD66_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6144272.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            17992..18909
                     /gene="rbsK"
                     /locus_tag="IVD66_000015"
     CDS             17992..18909
                     /gene="rbsK"
                     /locus_tag="IVD66_000015"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HAP6144273.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            18937..19332
                     /gene="rbsD"
                     /locus_tag="IVD66_000016"
     CDS             18937..19332
                     /gene="rbsD"
                     /locus_tag="IVD66_000016"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002829567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HAP6144274.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            19332..20705
                     /locus_tag="IVD66_000017"
     CDS             19332..20705
                     /locus_tag="IVD66_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6144275.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            21062..23206
                     /locus_tag="IVD66_000018"
     CDS             21062..23206
                     /locus_tag="IVD66_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP6144276.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(23258..24298)
                     /locus_tag="IVD66_000019"
     CDS             complement(23258..24298)
                     /locus_tag="IVD66_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAP6144277.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(24575..26377)
                     /locus_tag="IVD66_000020"
     CDS             complement(24575..26377)
                     /locus_tag="IVD66_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6144278.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(26391..27143)
                     /locus_tag="IVD66_000021"
     CDS             complement(26391..27143)
                     /locus_tag="IVD66_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6144279.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(27152..27514)
                     /locus_tag="IVD66_000022"
     CDS             complement(27152..27514)
                     /locus_tag="IVD66_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP6144280.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(27690..28562)
                     /locus_tag="IVD66_000023"
     CDS             complement(27690..28562)
                     /locus_tag="IVD66_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HAP6144281.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(28613..29101)
                     /locus_tag="IVD66_000024"
     CDS             complement(28613..29101)
                     /locus_tag="IVD66_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAP6144282.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(29239..30069)
                     /locus_tag="IVD66_000025"
     CDS             complement(29239..30069)
                     /locus_tag="IVD66_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HAP6144283.1"
                     /translation="MRLKHFLITGIGLMLTGGLLAGATYTLGAQKSLTWDNGPRLIDM
                     VTETKKIKDANKIVIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKK
                     STGAIISLEDTSAQITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSF
                     NEFTGGTITAKDELGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSL
                     HEMENSGYTIQTSGESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD
                     "
     gene            complement(30085..30693)
                     /locus_tag="IVD66_000026"
     CDS             complement(30085..30693)
                     /locus_tag="IVD66_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HAP6144284.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLVWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(30686..31003)
                     /locus_tag="IVD66_000027"
     CDS             complement(30686..31003)
                     /locus_tag="IVD66_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP6144285.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(31159..31887)
                     /locus_tag="IVD66_000028"
     CDS             complement(31159..31887)
                     /locus_tag="IVD66_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HAP6144286.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIFFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            32046..32927
                     /locus_tag="IVD66_000029"
     CDS             32046..32927
                     /locus_tag="IVD66_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP6144287.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(33164..34207)
                     /locus_tag="IVD66_000030"
     CDS             complement(33164..34207)
                     /locus_tag="IVD66_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP6144288.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(34210..34878)
                     /locus_tag="IVD66_000031"
     CDS             complement(34210..34878)
                     /locus_tag="IVD66_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6144289.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            35020..37356
                     /locus_tag="IVD66_000032"
     CDS             35020..37356
                     /locus_tag="IVD66_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6144290.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(37471..37782)
                     /locus_tag="IVD66_000033"
     CDS             complement(37471..37782)
                     /locus_tag="IVD66_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144291.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            37963..39438
                     /locus_tag="IVD66_000034"
     CDS             37963..39438
                     /locus_tag="IVD66_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HAP6144292.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPTMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            39485..40069
                     /locus_tag="IVD66_000035"
     CDS             39485..40069
                     /locus_tag="IVD66_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HAP6144293.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            40071..40490
                     /locus_tag="IVD66_000036"
     CDS             40071..40490
                     /locus_tag="IVD66_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HAP6144294.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(40771..41055)
                     /locus_tag="IVD66_000037"
     CDS             complement(40771..41055)
                     /locus_tag="IVD66_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HAP6144295.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(41407..42117)
                     /locus_tag="IVD66_000038"
     CDS             complement(41407..42117)
                     /locus_tag="IVD66_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HAP6144296.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(42114..43586)
                     /locus_tag="IVD66_000039"
     CDS             complement(42114..43586)
                     /locus_tag="IVD66_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP6144297.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            43724..44197
                     /locus_tag="IVD66_000040"
     CDS             43724..44197
                     /locus_tag="IVD66_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP6144298.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(44350..44901)
                     /locus_tag="IVD66_000041"
     CDS             complement(44350..44901)
                     /locus_tag="IVD66_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP6144299.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            45006..45536
                     /locus_tag="IVD66_000042"
     CDS             45006..45536
                     /locus_tag="IVD66_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HAP6144300.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(46019..46462)
                     /locus_tag="IVD66_000043"
     CDS             complement(46019..46462)
                     /locus_tag="IVD66_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6144301.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(46478..47638)
                     /locus_tag="IVD66_000044"
     CDS             complement(46478..47638)
                     /locus_tag="IVD66_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP6144302.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            48145..49845
                     /locus_tag="IVD66_000045"
     CDS             48145..49845
                     /locus_tag="IVD66_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144303.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(49947..50780)
                     /locus_tag="IVD66_000046"
     CDS             complement(49947..50780)
                     /locus_tag="IVD66_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HAP6144304.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(51084..53249)
                     /locus_tag="IVD66_000047"
     CDS             complement(51084..53249)
                     /locus_tag="IVD66_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6144305.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKQFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            53509..55803
                     /locus_tag="IVD66_000048"
     CDS             53509..55803
                     /locus_tag="IVD66_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAP6144306.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFKLLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            55796..56461
                     /gene="pgmB"
                     /locus_tag="IVD66_000049"
     CDS             55796..56461
                     /gene="pgmB"
                     /locus_tag="IVD66_000049"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAP6144307.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFTKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            56454..57461
                     /locus_tag="IVD66_000050"
     CDS             56454..57461
                     /locus_tag="IVD66_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAP6144308.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            57483..58502
                     /locus_tag="IVD66_000051"
     CDS             57483..58502
                     /locus_tag="IVD66_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6144309.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(58783..60151)
                     /gene="nhaC"
                     /locus_tag="IVD66_000052"
                     /pseudo
     CDS             complement(58783..60151)
                     /gene="nhaC"
                     /locus_tag="IVD66_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
     gene            complement(60260..61681)
                     /locus_tag="IVD66_000053"
     CDS             complement(60260..61681)
                     /locus_tag="IVD66_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6144310.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(61924..63801)
                     /gene="tdc"
                     /locus_tag="IVD66_000054"
     CDS             complement(61924..63801)
                     /gene="tdc"
                     /locus_tag="IVD66_000054"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAP6144311.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(64092..65348)
                     /locus_tag="IVD66_000055"
     CDS             complement(64092..65348)
                     /locus_tag="IVD66_000055"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HAP6144312.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     gene            65928..67229
                     /locus_tag="IVD66_000056"
     CDS             65928..67229
                     /locus_tag="IVD66_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAP6144313.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(67298..67897)
                     /locus_tag="IVD66_000057"
     CDS             complement(67298..67897)
                     /locus_tag="IVD66_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6144314.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            68151..69032
                     /locus_tag="IVD66_000058"
     CDS             68151..69032
                     /locus_tag="IVD66_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6144315.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            69045..70655
                     /locus_tag="IVD66_000059"
     CDS             69045..70655
                     /locus_tag="IVD66_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HAP6144316.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(70732..71391)
                     /locus_tag="IVD66_000060"
     CDS             complement(70732..71391)
                     /locus_tag="IVD66_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP6144317.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(71674..72339)
                     /locus_tag="IVD66_000061"
     CDS             complement(71674..72339)
                     /locus_tag="IVD66_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144318.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(72486..73091)
                     /gene="dhaL"
                     /locus_tag="IVD66_000062"
     CDS             complement(72486..73091)
                     /gene="dhaL"
                     /locus_tag="IVD66_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HAP6144319.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(73119..74102)
                     /gene="dhaK"
                     /locus_tag="IVD66_000063"
     CDS             complement(73119..74102)
                     /gene="dhaK"
                     /locus_tag="IVD66_000063"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HAP6144320.1"
                     /translation="MKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRVVAKNQKAEQ
                     VGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEADSGKGVLLIV
                     KNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAGTVLVHKIVG
                     DAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDEIEYGVGIHG
                     EPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQFVFMNDVLA
                     LLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTISW"
     gene            complement(74104..74499)
                     /gene="dhaM"
                     /locus_tag="IVD66_000064"
     CDS             complement(74104..74499)
                     /gene="dhaM"
                     /locus_tag="IVD66_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HAP6144321.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            74653..74973
                     /locus_tag="IVD66_000065"
     CDS             74653..74973
                     /locus_tag="IVD66_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HAP6144322.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(75085..75954)
                     /locus_tag="IVD66_000066"
     CDS             complement(75085..75954)
                     /locus_tag="IVD66_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP6144323.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(76050..77354)
                     /locus_tag="IVD66_000067"
     CDS             complement(76050..77354)
                     /locus_tag="IVD66_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP6144324.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(77351..77860)
                     /locus_tag="IVD66_000068"
     CDS             complement(77351..77860)
                     /locus_tag="IVD66_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144325.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(78035..80170)
                     /locus_tag="IVD66_000069"
     CDS             complement(78035..80170)
                     /locus_tag="IVD66_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6144326.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(80253..81908)
                     /locus_tag="IVD66_000070"
     CDS             complement(80253..81908)
                     /locus_tag="IVD66_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP6144327.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(81910..82224)
                     /locus_tag="IVD66_000071"
     CDS             complement(81910..82224)
                     /locus_tag="IVD66_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP6144328.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            82394..82654
                     /locus_tag="IVD66_000072"
     CDS             82394..82654
                     /locus_tag="IVD66_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HAP6144329.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            82668..82982
                     /locus_tag="IVD66_000073"
     CDS             82668..82982
                     /locus_tag="IVD66_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur reduction protein DsrE"
                     /protein_id="HAP6144330.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(83712..84266)
                     /locus_tag="IVD66_000074"
     CDS             complement(83712..84266)
                     /locus_tag="IVD66_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HAP6144331.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(84392..86321)
                     /locus_tag="IVD66_000075"
                     /pseudo
     CDS             complement(84392..86321)
                     /locus_tag="IVD66_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(86627..87343)
                     /locus_tag="IVD66_000076"
     CDS             complement(86627..87343)
                     /locus_tag="IVD66_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAP6144332.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(87344..89167)
                     /gene="glpO"
                     /locus_tag="IVD66_000077"
     CDS             complement(87344..89167)
                     /gene="glpO"
                     /locus_tag="IVD66_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HAP6144333.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(89181..90677)
                     /gene="glpK"
                     /locus_tag="IVD66_000078"
     CDS             complement(89181..90677)
                     /gene="glpK"
                     /locus_tag="IVD66_000078"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HAP6144334.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(90813..92273)
                     /locus_tag="IVD66_000079"
     CDS             complement(90813..92273)
                     /locus_tag="IVD66_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP6144335.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(92263..93558)
                     /locus_tag="IVD66_000080"
     CDS             complement(92263..93558)
                     /locus_tag="IVD66_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP6144336.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(93890..94567)
                     /locus_tag="IVD66_000081"
     CDS             complement(93890..94567)
                     /locus_tag="IVD66_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HAP6144337.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(94597..95688)
                     /locus_tag="IVD66_000082"
     CDS             complement(94597..95688)
                     /locus_tag="IVD66_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HAP6144338.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(95789..96223)
                     /locus_tag="IVD66_000083"
     CDS             complement(95789..96223)
                     /locus_tag="IVD66_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP6144339.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(96807..98264)
                     /gene="ascB"
                     /locus_tag="IVD66_000084"
     CDS             complement(96807..98264)
                     /gene="ascB"
                     /locus_tag="IVD66_000084"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP6144340.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(98261..100156)
                     /locus_tag="IVD66_000085"
     CDS             complement(98261..100156)
                     /locus_tag="IVD66_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6144341.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(100214..101989)
                     /locus_tag="IVD66_000086"
     CDS             complement(100214..101989)
                     /locus_tag="IVD66_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP6144342.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(102039..103535)
                     /locus_tag="IVD66_000087"
     CDS             complement(102039..103535)
                     /locus_tag="IVD66_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP6144343.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(103729..105351)
                     /locus_tag="IVD66_000088"
     CDS             complement(103729..105351)
                     /locus_tag="IVD66_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAP6144344.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(105679..106992)
                     /locus_tag="IVD66_000089"
     CDS             complement(105679..106992)
                     /locus_tag="IVD66_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAP6144345.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(107237..107461)
                     /locus_tag="IVD66_000090"
     CDS             complement(107237..107461)
                     /locus_tag="IVD66_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144346.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(107481..107849)
                     /locus_tag="IVD66_000091"
     CDS             complement(107481..107849)
                     /locus_tag="IVD66_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP6144347.1"
                     /translation="MIQKTRVMLYVNDVEMICRFFVEKIGAEISETIELPEEFKSIVL
                     SISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETIYENMEEPGEITDNNGILT
                     FNFSDPEGNYFVIGKAESSD"
     gene            complement(108046..108756)
                     /locus_tag="IVD66_000092"
     CDS             complement(108046..108756)
                     /locus_tag="IVD66_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144348.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(108774..109271)
                     /locus_tag="IVD66_000093"
     CDS             complement(108774..109271)
                     /locus_tag="IVD66_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6144349.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(109308..109760)
                     /locus_tag="IVD66_000094"
     CDS             complement(109308..109760)
                     /locus_tag="IVD66_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003331879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP6144350.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(109895..110500)
                     /locus_tag="IVD66_000095"
     CDS             complement(109895..110500)
                     /locus_tag="IVD66_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAP6144351.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(110950..111570)
                     /locus_tag="IVD66_000096"
     CDS             complement(110950..111570)
                     /locus_tag="IVD66_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6144352.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(111572..112441)
                     /locus_tag="IVD66_000097"
     CDS             complement(111572..112441)
                     /locus_tag="IVD66_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HAP6144353.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(112464..112871)
                     /locus_tag="IVD66_000098"
     CDS             complement(112464..112871)
                     /locus_tag="IVD66_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAP6144354.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(112890..114179)
                     /locus_tag="IVD66_000099"
     CDS             complement(112890..114179)
                     /locus_tag="IVD66_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6144355.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGDFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(114206..114508)
                     /locus_tag="IVD66_000100"
     CDS             complement(114206..114508)
                     /locus_tag="IVD66_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6144356.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(114533..116626)
                     /locus_tag="IVD66_000101"
     CDS             complement(114533..116626)
                     /locus_tag="IVD66_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP6144357.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(117115..117879)
                     /locus_tag="IVD66_000102"
     CDS             complement(117115..117879)
                     /locus_tag="IVD66_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HAP6144358.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(117990..118859)
                     /gene="mdcB"
                     /locus_tag="IVD66_000103"
     CDS             complement(117990..118859)
                     /gene="mdcB"
                     /locus_tag="IVD66_000103"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HAP6144359.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(118884..119960)
                     /locus_tag="IVD66_000104"
     CDS             complement(118884..119960)
                     /locus_tag="IVD66_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HAP6144360.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(119984..120577)
                     /locus_tag="IVD66_000105"
     CDS             complement(119984..120577)
                     /locus_tag="IVD66_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HAP6144361.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(120581..122257)
                     /gene="mdcD"
                     /locus_tag="IVD66_000106"
     CDS             complement(120581..122257)
                     /gene="mdcD"
                     /locus_tag="IVD66_000106"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HAP6144362.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(122247..122546)
                     /locus_tag="IVD66_000107"
     CDS             complement(122247..122546)
                     /locus_tag="IVD66_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HAP6144363.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(122648..124294)
                     /gene="mdcA"
                     /locus_tag="IVD66_000108"
     CDS             complement(122648..124294)
                     /gene="mdcA"
                     /locus_tag="IVD66_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HAP6144364.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(124301..125212)
                     /locus_tag="IVD66_000109"
     CDS             complement(124301..125212)
                     /locus_tag="IVD66_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAP6144365.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            125332..126189
                     /locus_tag="IVD66_000110"
     CDS             125332..126189
                     /locus_tag="IVD66_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP6144366.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(126376..126738)
                     /locus_tag="IVD66_000111"
     CDS             complement(126376..126738)
                     /locus_tag="IVD66_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144367.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            127084..128523
                     /locus_tag="IVD66_000112"
     CDS             127084..128523
                     /locus_tag="IVD66_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP6144368.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(128530..131082)
                     /locus_tag="IVD66_000113"
     CDS             complement(128530..131082)
                     /locus_tag="IVD66_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HAP6144369.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(131196..132527)
                     /locus_tag="IVD66_000114"
     CDS             complement(131196..132527)
                     /locus_tag="IVD66_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6144370.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(132493..133971)
                     /locus_tag="IVD66_000115"
     CDS             complement(132493..133971)
                     /locus_tag="IVD66_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6144371.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(134276..136111)
                     /gene="tdc"
                     /locus_tag="IVD66_000116"
     CDS             complement(134276..136111)
                     /gene="tdc"
                     /locus_tag="IVD66_000116"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAP6144372.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            136581..138008
                     /locus_tag="IVD66_000117"
     CDS             136581..138008
                     /locus_tag="IVD66_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP6144373.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(138100..138465)
                     /locus_tag="IVD66_000118"
     CDS             complement(138100..138465)
                     /locus_tag="IVD66_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAP6144374.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(138462..138827)
                     /locus_tag="IVD66_000119"
     CDS             complement(138462..138827)
                     /locus_tag="IVD66_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAP6144375.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(139019..139267)
                     /locus_tag="IVD66_000120"
     CDS             complement(139019..139267)
                     /locus_tag="IVD66_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144376.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            139266..139394
                     /locus_tag="IVD66_000121"
     CDS             139266..139394
                     /locus_tag="IVD66_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HAP6144377.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            139451..141145
                     /locus_tag="IVD66_000122"
                     /pseudo
     CDS             139451..141145
                     /locus_tag="IVD66_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
     gene            141149..141268
                     /locus_tag="IVD66_000123"
                     /pseudo
     CDS             141149..141268
                     /locus_tag="IVD66_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            141350..141541
                     /locus_tag="IVD66_000124"
     CDS             141350..141541
                     /locus_tag="IVD66_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144378.1"
                     /translation="MDLLPQMQAFEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDL
                     LPQMQAFEHRLPRGYEKGV"
     gene            141919..143052
                     /locus_tag="IVD66_000125"
     CDS             141919..143052
                     /locus_tag="IVD66_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAP6144379.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            143083..143403
                     /locus_tag="IVD66_000126"
     CDS             143083..143403
                     /locus_tag="IVD66_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144380.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(143432..143896)
                     /locus_tag="IVD66_000127"
     CDS             complement(143432..143896)
                     /locus_tag="IVD66_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6144381.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(144028..145282)
                     /locus_tag="IVD66_000128"
                     /pseudo
     CDS             complement(144028..145282)
                     /locus_tag="IVD66_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736485.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(145311..145628)
                     /locus_tag="IVD66_000129"
     CDS             complement(145311..145628)
                     /locus_tag="IVD66_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP6144382.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(145654..145974)
                     /locus_tag="IVD66_000130"
     CDS             complement(145654..145974)
                     /locus_tag="IVD66_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6144383.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(146438..147853)
                     /locus_tag="IVD66_000131"
     CDS             complement(146438..147853)
                     /locus_tag="IVD66_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP6144384.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(147870..149186)
                     /locus_tag="IVD66_000132"
     CDS             complement(147870..149186)
                     /locus_tag="IVD66_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6144385.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(149336..150034)
                     /locus_tag="IVD66_000133"
     CDS             complement(149336..150034)
                     /locus_tag="IVD66_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAP6144386.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(150323..151312)
                     /locus_tag="IVD66_000134"
     CDS             complement(150323..151312)
                     /locus_tag="IVD66_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HAP6144387.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(151392..152225)
                     /gene="msrA"
                     /locus_tag="IVD66_000135"
     CDS             complement(151392..152225)
                     /gene="msrA"
                     /locus_tag="IVD66_000135"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP6144388.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(152400..154028)
                     /locus_tag="IVD66_000136"
     CDS             complement(152400..154028)
                     /locus_tag="IVD66_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144389.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIRLVSKGFKNADFIAI
                     FKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNNDL
                     TTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAKLL
                     QFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFNQK
                     IISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNLPY
                     KTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGVAD
                     IKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(154015..155349)
                     /locus_tag="IVD66_000137"
     CDS             complement(154015..155349)
                     /locus_tag="IVD66_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144390.1"
                     /translation="MDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
BASE COUNT        45871 a        32101 c        26971 g        50438 t
ORIGIN      
        1 tctatcactt tccttttttc acacgactcc cggtttcttt gataaatctc gatactttca
       61 attttcttga atttttcatt tgaggtacac atagatacag acgatttctt gctctagtca
      121 tcgcaacata aaatagtctt cgttcttctt ctatcgtcgt tactggttct gcttttattt
      181 cattaaagtc gattactttc ttttctgtcg ctccgttata aggcaaactt ccttcgttac
      241 aaccaatcaa aaagacattt cggtaactaa gacctttact tttgtgaatg ctctggatac
      301 atagtgcatc aagttttcct tgtctgtaag caatcaagcg ggtttttaat tctttagctg
      361 tcgcttgggt ttcttgcgat aaggcttgga gtcttctgaa agtagcatgc tgctttactt
      421 cttctcgtat ccattcttga tcactctggt cgatttcctt agctatacgt ggcagatgaa
      481 gatagctttg aacaagcgaa tagatttctt gatgctggtc tgttttacgc aacgcttcct
      541 caaactctcg gatttctgca gatttcgatt ttaaattggg gcttatcgac aaaatataat
      601 ctgcaacgga tatattttga tatttaggag aaaagtattg atcgcattca ctttttttca
      661 ggtagcagtc tgccatcagc tgccggagca attgctggta ggcctgattt ttcttttgca
      721 gattcagtgc tgtttgccaa tgaacaattt tttgatagaa atgttggaaa gacttgatac
      781 caaagatacc ttcatatgga ctatctgctt ccagtacaaa aggaatattc gttttcagca
      841 gagattggac aagctgctgc gtttgtgaag ctgatcggta taatatgatt gattccttat
      901 atttcccatt tttttgaata aatgtctgaa tttgtttgat tagccactga ctttctgctt
      961 tagtatcaga aaacaaatag gcttccataa cacctgcttc tttttgtgct ggaatcatcg
     1021 cctttggtat ccgatcattt ttattatagc tgatcaatct atttgctcct tggacaatag
     1081 ctgcccgaga acgataatta gttaataaga aaagagtttt ggtaggatat tctttttcaa
     1141 agttcttgat gtatgctggc tctgatcctc tgaatccata gatactctga tcatcatctc
     1201 caacaacaat caacttgatc ctgttttcct ttgtcatccg tttcacgatt tcccattgaa
     1261 gtggattagt atcttgaaat tcatcaatga atagataatc atatttttgg ccgatataat
     1321 gctggatctc ctcattctcc aaagcgcttt tcagattttg gagtacatca ttgaactcta
     1381 gcaattgctg gcttcttttt tgttcttgga gttccgtgag caatccatac agtcgttctg
     1441 atatcggctg tcgtgcattc ttatcaatgg aatcatattt ttctttaact aactgaacca
     1501 tttcttctac tgaaaggttc atattctgcc aatagtctaa ccgagaagca atcgtttttt
     1561 ctccatattg atcaaatata taaagattat atttacgtat cagctgttgc aaaacagcat
     1621 tcactttttg tgcagtatcc tttgaaaagt ctccttgtat tccttgcatt gctacttcag
     1681 gaaattttcg acaaatttca ttgtatatcc taaaaaagat actatggaat gttccgatat
     1741 ggacagcggt ttttctctgg ctgaaattat ctactcgttt ttttagttca tttgcagcgt
     1801 tccttgtaaa agtgatcatt agtatgcgtt cttcgtctac ttgtttttgc gtcatcagat
     1861 aaacagcttt tgcacagatt gtttgcgttt tgccgctccc agctcctgct atgattcgaa
     1921 gatgtttctt catatcatat gtgatagctg ctttttgttc ttgattgaag cgattatagg
     1981 aacgtttctc catcatttta aagaaagagc tgtttccttc actttctttt acttgtactt
     2041 cttcctcaat aagtccgggt gcttcgccat aagccgcttc ataggtagca atgatttctt
     2101 cttgtagccg aaagacttgt tgaagctttt tatacttgtt ctcccagcgt ttcaattctt
     2161 tttgtaatcg gagaatttct ttttcattca actgattgat ttccttccca tctttcttct
     2221 ttgaatttgt ttatttcaag ttggttattt aaagtttcgt tgtctatttt ttctttatac
     2281 taacagacct ttctaaaaat gaaaatggga agcgatatga ttttagtttt ctgaaaattt
     2341 ttcctttttt tcaatcgttt atgctaagat aaggaagaca aaaatattca taaaaggtga
     2401 tgaaaaaaat gcagacttcc tttcacgagg ggcgtacaat aggacttttg ctgacattta
     2461 tcggaggagc catggacagt tatacttata tccaatatgg tgcttttgcc tctgctcaaa
     2521 ctggcaatat cattctatcg atcatccaag catttgacgg agaatggcta agtgttggta
     2581 aaaaagtatt gtctaccctt ttctttttct tagggattct tctaacaaag tatctaattg
     2641 attattttag aaaaaaagaa aaacatttct ggcgcttgtt tgttctatat tatgaagcag
     2701 tgattttttt ctttgttagt ttgacacccg tccatgagca tcccgcatta gtaacgattt
     2761 tgattgcttt tactgcatcg atccagtggg tagcttttga taaaatcaac gggcgtgcct
     2821 acactaattt atttacaact ggaaatttaa aaggggtagc aacgaactta tatgattatt
     2881 gtatttctaa agaaaaagca gattttgatc gatttttcca ctatctaagt gtcgttcttg
     2941 cctttatcgc aggagctatt gtccttgttt tctgtcatca tctgtttggc gcccattcga
     3001 ttttgatcgt ttccatttta tttttgatca tggccctcac tcagacattt catttatggc
     3061 aattttatca tacgaatcgg ttcactattt gatctcaatg aatcaaaaaa actaagcaag
     3121 atgctgctca cagagaaata tctgcgagtg agcaatttgc ttagttttta tattatttag
     3181 ttgtaaagat tccctttgct ttcgggttat ttgtagtgta gcggatcgac tgggcatctg
     3241 cctcttctgt cattttcttt gcccgcatct tgatttcttg tacgatttgt tctccacatg
     3301 ccggatcggc tacgaaatca tatttgtccc catcgatcac tattttggga catatatcaa
     3361 actgttcata ccactcttcg tatcgtcgat tgagttcttt atagtaggaa tagagttcag
     3421 gatcttgttc tagctgttca tattcccggc ctcttttttt gattctcgct aacatagttt
     3481 caaaggatac acgaatataa accagtagat ctggtttctt ttgtggcgaa atttcttcta
     3541 actccttcag catcgtttct aaaagacctt catactgctt tacttctact tcagaaacac
     3601 gccctaaatc tgcattcaaa tgaaacagca tactatcttc gtagatggag cggtctagta
     3661 cgttgtcatc atggctgaaa gcatctttga ttgccaaaaa gcgtttgttc aaaaagaaaa
     3721 tctgtaataa aaaagtatac ttttctggat tagaataaaa tagcggcaat acttcattat
     3781 cttccacgtt ctcataaaaa ggttttgttt ctaaatcttg ggcaagcatt tcagttagtg
     3841 tgcttttccc tgcaccgatc gttcctgcaa caatgatcac aattatcggc atccttcctg
     3901 taataaaatc tgttcttcat tttactactt catttataga aataaaagcc ttgactttat
     3961 ctgctcctta aaagctactt ctctaaaagt agccaaaagt aactcctatt catgaaaata
     4021 aaggctgtga caaaagtctt gtcgcagccc ttttttcaaa taaacagtat tctcctgcca
     4081 acacctcggt cacaaggcaa tattcataaa acatgaaaag ctgtttttta acattattcc
     4141 ttgtaactca gagctaaacg ggagactcac aacctcttta tgctctcaac attttatctg
     4201 tttttattct tctattgtac ttgatttgcg tacaactaac tgccagtgca gattatgagc
     4261 ggtatcattg tcttctactg cgcatttcat gacacgtatc atcacactat tttcatagat
     4321 tttttctatt tttcctttta ttggtgattc aaataaatca gatttaaatg catatgtttc
     4381 gccgacttca aacaattgtt cattttccat aagaatccct ccatcacctt ttataaggtc
     4441 agtaattttt taacataaat cactcgaaaa agcacaaact tgtcataaaa agtacttttc
     4501 gtatcaaaac tgtcactttt tttggtaagg ttcttggaaa acgaagattt ttttaggaga
     4561 tcatgacggt tttgatgtca aaaccacttt ttatgaaaca aaagacgttt tttatttttt
     4621 ttagcataaa atttgtggtg gaggtacgta tgagatgaaa gataaagttg tgaacaaatt
     4681 attagaagcc ttattcagcg gagacaaatc ggaagaagat atggtgtatg tccaagtaaa
     4741 atttgtctta gaagttttat tgaataatct tggaaaacta gcggtcgttc tagtcttttc
     4801 tctggtgaca ggctcatggg cggaaacagg aatcaccttt ctttcttata tctgcatccg
     4861 cagatatgct tatggattgc attccgactc tgaattcgtt tgtctgctgt ggacactact
     4921 ttatttatgg ggcgttccct tggtgatgaa acatctgcaa ttgactatct ccttcccaat
     4981 gatggtcttt ttgttaatca gctgcttttt gttactgctt cgctatggat caagaggtac
     5041 agcaatcaat cccattgaac ccgagaaacg tcccccatta ttaaagaagg cgatcagcat
     5101 gtttctaatt ttttctctca ttacgttatt tttctcagct tcttactttt ctacctattt
     5161 gctacttggg attgttttag aaatagctac gttgcttcct attacaaact acttgatgaa
     5221 ttttggagga atctttcatg aaaaaaacaa tcattaaaca attaactaac ttatctgact
     5281 tttttgtatc tggctgctgc tttggtatga gttctgaatt caaaatccct gaaaaattaa
     5341 aaaaataata cgccaattgt gctataattt ggtaaaaatc aatgggagct gtactttatg
     5401 tttttatggt ccatagcgtt gcaatatttg atttacacaa tttgtatctt attgattgac
     5461 catcacatcc gatacaaata tctgtttgcg ggagtcattc tgatttcttg tattttgatt
     5521 ggatgggtct attcgatttt agggattttt actgctctaa ttgctatagg aatgctgatg
     5581 cttacttttt tcttcttttc gacttcgcgt caacaattgg tttacgcgct tccttttggg
     5641 ttattgacgt cgcttttagg agatcactta acaagcatcg gcgatttttt tgttttgaaa
     5701 tcttcggtta ttgaaccagg agattcattg cagtattttc acattgtctt atccgctttt
     5761 ttatctgctt tattagcttt ttgtttaaaa aaatcgttag agacttggtt tcacactgtg
     5821 gaccgccgta tgatcggtac gatcgggaca ttgatattat ttacatacta tatcattatt
     5881 ttttataccc gtttttctgg tgaaacacct gatgtcttag ctttgaatac gagttttttc
     5941 attctatatc tgtgtgttgg cctgatcatc ttggtttatt attggaaaat ctctaataag
     6001 aaattagctg atcagttatt agagcaacaa gtcaggatgc aacaggatta tatcaaagat
     6061 ctagaaaaaa actatcaaga cttgagagaa ttcaaacatg attaccaaaa tctgcttttt
     6121 tctcttcaca gctatatttc agaaggcgac ttagaaggat tacggtctta ttatgatcaa
     6181 acgatattac ctacacgcca gatgatgaac ctttttccgg ccaatctaag tatgttggat
     6241 aatatgaaag ttcctgagat ccgtagttta ctgtcattaa aactcatgat ggcacaggaa
     6301 aaagggttga tcgtccagct tcattttcct gagccaatcg aactggatac gaaacatacg
     6361 gtaaaccttg tacgtatgct tggtattatc ttggacaatg cgattgaagg agctagtgct
     6421 gcaaagaaga aaaaaatcga attgaccata ctcaagaaga atcattccgt gatgattcgt
     6481 gtgatcaata caacaacaaa tacattaccg ttaaaccagt tgaaacaaaa agggttctca
     6541 acaaaaacaa atccaaaaaa cgaaggcctt ggcttgttta tcttggatga attgacaaag
     6601 accaatcctt atcttttcct tgaaacatca attgaaaacc agcgtttttc tcaaacgatt
     6661 tatatacaaa taaaataaag gagtaatgat atgattccca tttatatttg tgaagacgat
     6721 ccaaaacaat tagaagtttt atcaacggtg atcaaaaata gaatcatgat tgaaaactta
     6781 gacagttatg tccatatttc tacctctgat ccggaagaac ttctcaatgc agccaagatc
     6841 agaacttctt cttttggtat ttacttttta gatatcgaac tagaagacag tgaaatggat
     6901 ggtgtagcga tcggtaaatt gatccgtgaa ttagatcctt taggaaaaat aatctatgtg
     6961 acttcccata cggaaatgtc gatgaaaatc ttaaaaagca acatcgaacc gactgattat
     7021 atcgtcaaag aagatcttta tgatttaaaa gaaaatgtcg agcatatcct gagcaaaatt
     7081 ttcgaagatt ttcaaatgtc ccaaatccaa aaagatatct tcaaaataga gtttaatgat
     7141 gagatcaaat ttttaccgat caaagacatc caatattttt ctacttcgct aggagcgcca
     7201 cataaactgg aagtccattt gactcatgcc caattacaat tctatgagaa gatcaaagaa
     7261 atcgagaaaa tgcatcggaa ttttatccgt tgtcataaat cctatgttat caatacacaa
     7321 aatgtgcggt cgattaataa aaaaaccaga gaagtcacgt tggcaaacgg cgagaccatc
     7381 ccagcctcta tccgtggatt aaagaaattg atttcataaa aagaaccgaa tagtttggac
     7441 cgactaaatg accagccgat ccaaaccctt cggttctttt ttgcctatca gtgcaaaagc
     7501 atttcctgtg caatttcacg tccatccatt gtatctggat aaaatgttgg ccaattctcc
     7561 atttctttca gcaatacttc ttgactttca tttcctgcat ataaatgaaa atgttcggag
     7621 tcagccggtg caatcgtgtg atcactgaat tgaatatatc taaaagcgcc actttcctta
     7681 tcttctgctt cgaatagata ccttacgcca cggtttcctg cctcgtaggt caagatttct
     7741 ttccctacat aacgataatt tgaacgtttc gttgttccat tcttaaacgt aaatgccatc
     7801 tctttctcac tgatcttgat tgaagcaata tctgtttgat agcccttcgt ataatattct
     7861 ttatattctt gtgctgtctt atcctgattc aatttttctt tatattcaaa aacaggatca
     7921 aaagtcccat cttctacata cgtatctact gtttgccaag ttcctgccca atctgaaaga
     7981 gagcgatctt gtacatcctc gtcttcaaaa taaccgttgt agacgctctt ttcttttttg
     8041 ggggtcaaag tatcttctag cgggttttct gtctctgtcg tttttttcaa cgcttcgagg
     8101 tttgcttcca tgatagaaag atagttttct ccattttcta tttgttcatt cgtcaatcct
     8161 tccaaaggat tcaatacttc taaagataca cctgcttcgt ttgctaacgt tctggcaata
     8221 ctatctttgg cgttttcttc aaaataaata tagttgattc catgttcttt aacaaagtgt
     8281 ttcagttcag caattctcgc cgcagacggt tcttcactag aagaaagacc agcaatcgat
     8341 acttgattca atccatattc taacgctaga tagttgaatg cagcatgttg cgtgacaaaa
     8401 gatctttgtt ttgcttgctt aaaggtttct tgataaagct gatggagtgc ttgaagtttc
     8461 tcggtatagg ctgctgcatt ttttgtccat acttcctgtt tttctgggta agcttcaatc
     8521 agctgatcac gtatgtttgc tacctgcttg attgctaaac ttggagctag ccatacatgt
     8581 gggtctagct catgtgtatg gccttcttcc ccgtgttcat ggtcatgatc atgtccttct
     8641 tcacttcccg gaagtaaaag cataccttct gtcgctttta tcgtatggac attgccttct
     8701 tgtaatgttt tttggattgc ggggacccat gtttccatgt tttcatcatt ataaacaaag
     8761 atatctgtat cttggatctt tgccatgtct ttagcagaag gttcataatc gtgggaatca
     8821 gtccctgctg gaatcaataa ctctacttct ccttcatccc cgacgattgc ttttgtaaaa
     8881 tcatacatgg gataaaaggt cgtcatcacg ctcaattttt ctttactgtc ctcggctttc
     8941 ccacttgccc cgcaagcagt taacatacct gctaaaacca gcatggccaa tatacctatc
     9001 aatcgtttca tttatgacac tcctcttctc atcttctttc atttgaatgt tccgattcgc
     9061 ttttcgcaaa ccgtaatagt tacgttttag caacaggatt taatttatca tatggttaaa
     9121 agaactgtca agcgttttct tattttaatt gatgagaaag tttatatgaa tgattgacga
     9181 tatttttgca atcaacctct atcattttcc ttttataccc gcttttgtct ataatgaagt
     9241 tatagataaa ggaggaaaaa gagtgaaaaa agaaacagat acaacgaatc gtttgatccg
     9301 ctttttagga ggaaaaacct cttactatgt tttaggaata gttatcttac ttgcgctgat
     9361 catttatttt ttccatcaga tctcgtttat attcaagcct gtcggaatca ttatcgctac
     9421 tatcttgccc ccattattgt ttgcactgat cttgtattat cttttggaac cagtcatcaa
     9481 acgtttgagc aagcaccttt cgaggaactt gtcagtcatt atcgtttatg tgattatttt
     9541 atttttattg gggcttggaa gcatatggct tattcctttt cttgaagaac aggcaaagac
     9601 attgatcagt agtttgccag atttgtttca agattttcaa gagagtctcc gacaattttt
     9661 ggagaaaaca ccttttgccg attcatttaa tcaatttttc gcttctattg acgacgtgac
     9721 gtctgatata gctggattta ttggaaatta ttgggaaagt ggcgcacaac ggatcagcaa
     9781 cattttttca actgttacag ctatttttat tactttattt actggtccaa ttgtcgcttt
     9841 tttccttttg agagatcctc aaaaatttta tcagtcagtt ttagcgattg tcccaccagc
     9901 atttcgtaca gattttaaaa atttgacaaa gattgctaat caacaattgg gttcatttct
     9961 aaaggggcaa atcattgctt catttatcct tggagcagtc tactgggttt gtttcttact
    10021 gatcggatta gaatttgcta gtgttttagc tatttctgct gggttgttat gtatcattcc
    10081 atatattggg ccgtttatcg ccttctttcc aggtttgatc attgcattcc aagactctac
    10141 ttttatggct gtcaaatttg tcattgtctg gtttgccgta caacttctcc acggtgactt
    10201 ggtgattcct cgagtaatgg gtgatcgttt acagatccat ccgattacga tcttaatcgt
    10261 tttacttgtc atgggtgatc taatgggaat tgtgggcgtt atttttggta ttcctatcta
    10321 tacgttagtc aaattactcg ttacttttat tttccgtaaa ttcaaacaac gctacaataa
    10381 attttatggc gataaaggag agtatgaaaa ctcttcattt tctgaagaag attattttaa
    10441 ataaaacaca aaacgtcgat cttacgagaa tagctcgtag gaacgacgtt ttgtgttttt
    10501 gttttaattt ttcagcaaag caattgcctg gtatggtttt agctccagac tttgatgaag
    10561 aacagtatcg gaataattat cgataagaat attggcttct gtgaatcctt ctgggatggc
    10621 gatccttgta tctttatcat agaaatttgt taatacaagc agctgctgtc cttcaaattg
    10681 gcgaagaaag ccataaactt ccggatgatt tgcttcataa gcatgataat ctccttgtgc
    10741 aacgattgga tatgtttttc tcagccgaat caatttcttg taataggaca aaatagaatc
    10801 ttcagaagat agttcttttt ctacattaat ctcttctagc ttgcctccaa cttttaacca
    10861 aggtttccct gtagtaaatc ctgcttgttc tgtgtctgac cattgcatgg gtgttcgaga
    10921 gttatcgcga gattttgctt tgatccgacg aaacgcttct ttttctgtga atccttgttc
    10981 aaggagtaac ttataagcat tcaaactttc tacgtcaata tagtcggaaa tcgatgaata
    11041 gtctgggtcg atcatgccga tttcttctcc catataaata tagggcgtcc cacggttcaa
    11101 atggatcatg gttgctagca tctctgctcc ttgttttcga tactgatcga tagctacaaa
    11161 tcgattgagc gcacgtggct gatcatgatt attaaaaaat agagcattcc agccgttacc
    11221 ctcactcatc ttttctcccc atgtatgaaa tagtcgcttt aattctgcaa aatcaaatgg
    11281 aggagtagac catttattcc cattttcata atcgactttc aaatgatgga aattaaagac
    11341 cattgataat tcttctctac taggttctgt atacaagata caattttcga tcgtcgtaga
    11401 gctcatttca ccgactgtga tgatagtgga atccgtccca aacgttgctt ggttcaattc
    11461 ttttagatac gtatgggtga ttggtttgtc cgtatattca ggtttgccat cattttcttt
    11521 attatttttc aattgttcgt ctttaccgat aacattgata acatcgaaac ggaatccttt
    11581 tacccctttt tccatccaaa aacgaacaac tttgaatagt tcctctctta ctgcttggtt
    11641 ccgccagttc aagtcagctt gtgtccgatc atataagtgc aaataatatt tccccgtatc
    11701 tccaaatggc gaccaagcac ttccaccaaa ttttgatacc caatccgttg gctcttctct
    11761 taaaatgaag aagtcctgat aatgctggtc ccctgctagt gcttttttga accattcatg
    11821 ttctgtcgaa acgtgattca gcaccatatc gagcatgatt tctatccggt atttctttgc
    11881 ttcggctatt agctgttcga attcctccat cgtaccaaag ataggatcga tggctgtgta
    11941 atcagagata tcataaccgt tgtctttttg agggcttgga taaatagggt ttagccaaat
    12001 catgtcgatg cctagatcat tcagatacgg gagtttttct ttgattcctt ttaaatctcc
    12061 aattccatca ccattactgt ctttgtaaga tttgggatag atttggtaaa tgactttgtc
    12121 tttaaatgtc atggatattt acctccattc aactgattta ttacctacca caacttatat
    12181 atacaagtta tcatttatta ttataactga accgaaagcg tttgtaaaat ttatctttat
    12241 acattctaag aggtctgttg cccaataaaa aacaagagat cagacatgta tttgtctatc
    12301 ctcttgttta aaatagcaaa atattcttgt ttcttctata aatggtgttc aaaagctttt
    12361 atctacggca atcagtcttc tcaaatgtaa aacatgagga gctaatttta tttgagtatt
    12421 ctttttgctc gatgcaggac ggctttttta caacctctga ttcatggtgt tcaatcagct
    12481 gtccttcggt attagctcaa aaaacggcaa aatatgaaaa actattttgc cgtttgtttc
    12541 tctaatactc aggtcaaacc gctgatttca caacctctgt ttttattcat tcgatttcaa
    12601 cgcatcaatc atatcgatat gctttaattt gaaatgggta acaatcatca caataaccgt
    12661 aaatacgata gttaatcctg ctgataagac ataagcccac catgtgatca ctaatggaaa
    12721 gatgacattc tccatagacg cttgttgcaa gatgaagtca gtcaatatat atcctacacc
    12781 aaatcctccg atgattccta aaagagtaaa gatgatattt tctcgaacaa tgtacatcgt
    12841 gacttcttta tcaaaaaatc caaggacttt tattgtagat aattcgcgta cacgctcgga
    12901 aatattgata ttagttagat tatacaagac gataaaagcc agcagtcctg ataatacgac
    12961 aaagattaag acaaccgagt ctaagttcgc cattgattct tcttgcgttt cgatttgttt
    13021 ggacatgaaa gacgtatttg tcacagcgtc tgtggcaagc agtttctcgg aaagcatttc
    13081 ttcttctttt gttgtcatct tatctgtacg cagcaaaaat gcattatcca tcatcgattg
    13141 atcagtaact gaagcataat attcagggga catataaata aagctaccta gatagttttt
    13201 cacgatttct tttacttcga ctttccattc tttttgatct tcatcataaa gcgaaatatg
    13261 atctcctgta gataagtcaa atagttctgc tactttttgc gtaatagcga ttcctgtttt
    13321 aggcaaggag cgtgggttct cttcaagatc agttaaatgg ataaaacgat ccaaatcagc
    13381 tgttttactt ggtacgatca ctgtcagact ttgcgaagca tgtccttttt ttctcaattc
    13441 tacggtttga gtatgaatag ctaggatctc atttactttt tcttgcttct gcagcatatc
    13501 cgctgctttt tgacgactat cttccgtgga tgaatccaat gtaacgattg cttgatagtc
    13561 aatgatcgtt ccaaattgtt tggctgaaac agaacttaga gaatctttca atcccacgcc
    13621 tgcaaccatc agcccggcac atccagcaat tccgataatc gccataagca ttcttgactt
    13681 atatcggaag agatttcggt aactgatttt ttgattaaag ctaaggcgtg accacagcgg
    13741 agtgatgtat tcaagaaaaa tgcgtttccc tggcttcggt gctttcggtt gaagcaatgc
    13801 agcaggccgt tctcttaaat ctttgaataa aacgatcatt gcagcgccaa atgcggcaat
    13861 gaagaatgcg gcagctgctt gtaaaatcgg cggccagtca taaaaaataa gcgcactccc
    13921 aatatcatac cgctcgttag acagctcaaa aatgatcctt ggcaaaagat tcgttcctaa
    13981 tatcgttcct aaaacaatac ctatccctga ggctagactt gcatagattg catatttttt
    14041 tgcgatttca actttcgtat aacctaacgc ctttaatgtc ccgatttccc tgcggttttc
    14101 ttctaccata cgtgtcattg tcgtaaaggt gatcaatgcg gcaataaaga aaaagaaaac
    14161 aggaaaaaca ttggcaatcg cagcgatacg atcagacaga tcaccaaatt cttgaaaacc
    14221 gacattttct gaacgttcat tgtataggta tgatggttta gttaaatttt caattttttc
    14281 tgcatttcga ttcaattctt cctctgcaga ggccagttca cgttctttct caactaattg
    14341 cctttcttgt tcagcaagtt gagcttcttg ttgagataat gtttgaacag cgattgttcg
    14401 ttgcgcttca ggaagctgct ggatagttgc tgactgttgc gctaactgtt ttttagcatc
    14461 ttctaaccgt gttcttgctt gcgttgtttg tgctttgcca tccgctattt tttgctgtgc
    14521 cggttctaat tcttcgttgg ccgatttttt cagctcttct aagcgttctt cgggtcgatc
    14581 ttgtaaatac ttttctgcct tttcttgatt ttgctccatt ttatctttgt aagctttgct
    14641 gtacgtattc aaattcttta cgtttgtaaa atcaagatat aagacagaat aaatatctgt
    14701 tttaaaaacg gattcaggta aatagacaaa ataatcgacg ctaccatttc cgacgttcgc
    14761 gtatcctctc tccaaattgt tgatgaacaa tggagaacgg acaaagcccg tgatggtata
    14821 ctctttttct ttcaattcat ctgaatcaat ctgataaata tcaccgattt tatacccttc
    14881 atcttccgct ttttcatcca atacaagctg gtttggtttt tccgggagtt ttccatcagt
    14941 taattgtagc ttgttctgct tgttattttt gttataagaa aatatttgaa tcacttcgtt
    15001 tttgccagta ttggaataat agatctgttt tcctgtttct acttttgcat ctgggatctt
    15061 ttctgcttga gcaatatctt tttgtgtcaa gccaccagta gaaacgattt gcaaatcaga
    15121 aagtcctgct gtaccaacat agtgatccat cgttttttgc atgacaggtc cagcagtttt
    15181 gacacctaca aataaaagtg ttcctagcat gacaataagg atgattgcaa tgaatcgtcc
    15241 tttagattgc cgaatttcgc gaaaacctgc tttaagatat gttcttgttt tcataaaatc
    15301 cccctaccat acaatctcat caatggatga aggatgatca tttaattcaa cagaccttac
    15361 tttagcatca ttaatgtgaa tgactctatc agcgatgggc gctaaagcag aattatgtgt
    15421 aatgatcaaa acggtattgc cgtgttgtct gctagcgttt tgcaataatt tcaatacttg
    15481 cttgcccgtt tcaaaatcca gcgcgcctgt cggttcatca cataaaagaa gtttgggatt
    15541 tttagctagt gcacgagcaa ttgaaaccct ctgctgttcg cctcctgata attgggacgg
    15601 aaagttattc aatcgatgag ctaggcccac ttgcctcaat acctctacag gatcaagcgc
    15661 atcaggagaa acttccgttg ccaattccac attttctttt gctgttagat taggaacgag
    15721 attgtagaat tggaaaacga accctacatc tgttcgtcgg taagcagtaa gctgtttatc
    15781 tgaaaattgc gcaatatctg tgtcatcaat aatgatctga ccttcatcag gtgtatccat
    15841 cccacctaaa atattaagaa tcgttgactt tcctgctcca cttggaccaa gtataatcac
    15901 taattcgcct ttttcaattg aaaaagaaat atcgtcattt gctgtaatgg tcgtttctcc
    15961 cattttgtat cgtttgtatt cattttttac ttcgacatac ttcactctga ttcctccatt
    16021 ttcacgatat ttctcgctat atctatgcat cgaatgcgtt ttctcacact tatttatttt
    16081 accactgaat ttctctagac taaagaaagg aatcctttaa tttagttgac aaataaacga
    16141 tttatgattt acttacataa aaaacattgt tatttgaaag aaggaacatc atgaatgatt
    16201 taaaggaaaa tatgattttt gatttatcaa aaactgcttt tgtcgcgatc gacatgcaaa
    16261 aagagatcgt aaataacggt acactctctc cacacactgc agcatctatt ctgacaaaca
    16321 atgatttgtt agtaagaaca ttgaaacgta ccgctgcctt gaaagtttta gtgaacgtag
    16381 acatctccac tttcccttat ttgagtcaac aaactgatat gggtggaatg actgcttctg
    16441 tacctccaga attcactgat ttacttttga aggattcttt gaaagataca gataatatgt
    16501 tgactatcac aaaatacaat ccaagtgctt tttttggtac ttctcttgat cttcaacttc
    16561 gccggcgtgg aatcgaaact atcattttaa gcggtgtagc gacaacaaac ggtgtatatg
    16621 ctactgcatt agatgccttt caacacgggt accatatcgt gcttgctgaa gatgcttgca
    16681 gtgatcgtga caaagaatcc catcaattgt tcataaaaaa gatatttccg aaaactgcac
    16741 gagtacgctc aacgaaacaa ataatcgaag ctatccaaca aagcaaataa gtactggcac
    16801 acgtgatttt catttacttc tttttgattt catgggaaaa taaccacagg atttagatag
    16861 gagtatgaac atggtgaaaa aaaagatcac aatcaaagaa gtcgctaaac tttccggcgt
    16921 ttcaatcaca actgtctcct tgatattaaa tggaaatacg gagaaattca gtccgaaaac
    16981 tgttcagaaa gttttagctg ccaaagaaga attaggctat cagcctgact attttgctag
    17041 acaaatgatt accaaggaaa cgaaaacaat tggtgtactc gttcctgata tcacgaatcc
    17101 attcttcagt acactgatgc gaggaattga ggatatcttg tataagcaga atttcgtcac
    17161 gatattatgt aatgctgatt ctgatcatca aaaagaaatc gaatatctag ccgagctcac
    17221 acgtcgaggt gtggatggat tcattatcgc gacttctgct gtctctacag atgcaatcaa
    17281 cgaaaatttg aaaaaacaag gccggccctt cattgttttg gatcagaaaa aatctgaagg
    17341 atttagtgat gccgtacgaa cagacgattt tcgcggtggt tacctagcgg gcatgcactt
    17401 gcttagtcta ggacatcaaa cgatcgccct tgtctatcct gaaaatccac cggaaaatgt
    17461 ccacgctcgg attgaggggt ttaaatctgc tcttgatgtt taccaaatcc ctcacgacca
    17521 actgatcctc ttacctacac agttctcaaa acaaggtggc taccagatca cagcagaact
    17581 tcttgattct gctgcaactg gtgtgtttgc tttaaatgat gaattagctt ttggattata
    17641 tcgcggatta gaggaagctg gaaaaagcat ccctgaagac tacagcatta ttggctatga
    17701 taatatagat atgtgcgagt atatcaagcc gaaactgaca acgatcgcac aaccaatctt
    17761 cgaattggga caaacatctg ccaagttatt gttagatcgg atccaattcc cagaaaaaga
    17821 atgggaagaa aaaagattac ctgtacgatt agaaaaaaga ttttcaactg cacccttgaa
    17881 atagctttca aggtgtgcta tatttttatc gaactattaa aacgttttac taaaacgttt
    17941 taaaaaataa ttttcccatc aaaataaatg agatagttgg aggtttgtaa aatgaacacg
    18001 gttacagtaa ttggaagtat taatatggac actacccttc gtttaaccaa catgcccaag
    18061 ccaggcgaaa cgatgcatgc gcatgagatt tttcacgctg gcggaggtaa aggtgccaac
    18121 caagcagtgg cagccaaacg ttcaggcgca cggacatctt ttattggagg cgttggggct
    18181 gacagcgaag gacaacagtt attagatcta ctgacaaaag aaaacatcga tacatctggg
    18241 atagctgaaa tccaaggcgc cacaaccgga caagcaatga ttatggtaga cgcagcagga
    18301 gaaaatagta tcttgatcca tgcaggggca aataatgctt tccatgaaca agaagtccta
    18361 aaaaacaagc aactgattac aaacagtgac tttattattg ctcagtttga aagtagctta
    18421 gatgcgacga tcctagcttt ttctattgca aaagacgcag gaaaaacaac gatcctgaat
    18481 cctgcaccag ctcgtgaaac gattcctact gaactacttg aaaagacaga tatcattata
    18541 ccaaatgaaa cagaaacaga aatcattaca ggaatcagag tgacagatca taacagtttg
    18601 gtcgcagcag ccgaaaaact ccatgaatta ggtattggaa cagtaatcat tacactaggc
    18661 agtgccggcg ctttctatca tacagaaaaa gaacacggta tcgtccctgc ttttaaagtg
    18721 gatgccgttg acacaacagc cgcaggtgat acatttattg gcgcattaag cagcacactt
    18781 cagccagacc ttagtaactt gaaagaagcg atcctttatg gaaatctagc ctcttctgtt
    18841 gctgtgcagt cttatggtgc gcaaccttct atcccttacc gcgaagcttt agaacaatca
    18901 gcagtctaaa attaacaatg agaggaagaa acaaacatga aaaaaggaaa agtaatcaat
    18961 tcagatattt cacgagtaat cgcacaaatg gggcactttg ataaattaag tatcggggat
    19021 gcaggcatgc ctgtcccctt tggtactgaa aaaatagatt tggctgtctc aaacggtctt
    19081 ccaagttttt tatctgtttt agaaaacgtt ttagaagaac ttgaggtaca atcgattgaa
    19141 ttggcggaag aaataaagac aatgaacccg gaaatattgg aaaaaatcaa attattgtta
    19201 ccagatacac cgattagctt tatcccacat gaagaaatga aaaaagagtt gaataactgt
    19261 catgcattta ttcgtacagg cgaaatgaca ccttacgcca atattatatt agtgagtgga
    19321 gtggtcttct aatggaaacg acaatgaatc ctgaacagat ggtactgtcc gagcagattc
    19381 atatgctgat tgaacagttg ggaggaaaag acaatattga ttctgtcctt ccatgtgcga
    19441 ctcggcttcg tatcaaattg aaaaaacagc cagtagccaa tgcagaaaaa ttaaaacagc
    19501 aaatcccttc cattaagtat ttcattttac tcgatagata tgcagaaata atcatggatc
    19561 agggattggc tcctgcttac aaggaattga cgcgtcaaat cgatcattca gctccgaaag
    19621 aaaagctaaa tccgatcgaa aaactatttg gtttgatatc ggaaatcttt acgccgatca
    19681 ttccgctgtt tgccggttct ggtatattaa aaggtctggt tgttttagcg actacgattg
    19741 gctggcttag tgaaacaagc ggaacttatc atattttgtc tgctgcgtcg aatgccgtct
    19801 tttattttct gccaatcttt cttgcttttt ctgctgccaa aacgtttaaa gtgaatggat
    19861 atattgcggc tgtcattgct gcagcactga ttgaaccgaa tctgacctct ttactttcag
    19921 acagtggcaa agcagctact gattttctgg ggattcctgt agtactgatg cagtatacgt
    19981 ctactgtcat gccggcgatt ttaggtattt tcttttattc ttttgttgaa aaattcctca
    20041 aaaaatatat tcgcgaaaat atgcaattag tatttgtacc tttactttca ttagttatca
    20101 cggttccttt gacgttaatg gtattcgggc ctgcgggtgt ttaccttggc gaaggtttag
    20161 ctgccgcaat tacttggatg atggatatta acggaccgat cagtggcgca atcatcgctg
    20221 gtggttggaa tattttggta atatttggta tccaatgggc tgtaaaccct gtcatgatca
    20281 gtaatatctc tgcttatggg ttcgaccgaa tcgttccgtt gacaggagca gccaattttg
    20341 gaatggctgg tgcagcttta ggtgtatttc tgcgaagtaa acgttcaaaa acccgttcga
    20401 tctccggttc tgcttttgct tcgattttac ttgcgggagt gaccgaacca actgtttacg
    20461 gaattgcgat cccattgaaa aaaccatttg ttgctgcttg cattggtgca gctgctggtg
    20521 gagctgtaat gggatttgcc caagtgaaag cgatcgcttt tgtatttggt agtctgacca
    20581 cattgcctgc attcatttcc ggtacttttt tctggtactt agcaggactg gctgttagtc
    20641 tagtcgtagc aatgatcact actctcgtta gcgggtttga tgaagaccta atgtcttatg
    20701 aatagttaat gaaaaagact gaagtatgag atgtttatca catatttcag tctttttctt
    20761 tttaggatca ttatttttat aaatttttgt gatactttcc aaactttggt ataatttaca
    20821 tatgcataac catttttatc cccacttgtt tatccccaaa caaaggtggt ctatgcaata
    20881 aaatgaacgt caaagaaaaa cgaatgaatg ctcgttgctt atttacaaat tgttttattt
    20941 agaatacaca gacagattta tgaaaagaaa aagcttttcg acacgattat ctgttccaaa
    21001 aaatgtctaa tgaatgctga ataagacaga aaatcaatga aaggaaaagg actagtttat
    21061 tatgaaaaat aaaaaaacga tacgtttgct agctgctact tggctgattg ctccgtctgt
    21121 tttgtcgacc aataccgtat ttgccgtaga taatcaaata gctgatcaaa cagtcacaac
    21181 agatacgact acatccagct cagctactag tgaaacaacg gattctttta cagaagaccc
    21241 aactggaaca actaactcaa caacaggatc gaccgagcca actgaaattg atccggctga
    21301 tccatcagaa aatgaaaagc cagccgagac atattccctt acaattgctc cttctttgat
    21361 tggtaagatc caactgactg cttcgacagc ggattcccct gaacagcaac ctttggatat
    21421 tacggaaagt ggaacggtag aaggtttatt agcggaaacg aaggtaactt acactattac
    21481 gccagctgaa ggtgaacaaa ttgcttcagt cgctgttaat ggtgccaaag aagtaaatta
    21541 tgatgcaaag acctttacag taggtacgaa caatttatct attactgcag aatttaaagc
    21601 tggaccggat acttcaacag agaaaccaac tgatcctagt gaagaagtcc ctagtacacc
    21661 agatccggaa acgccaaaca aaccagatgt gggtaataac aacaataata atggttcaaa
    21721 taattcaaac aataataaca ataattcgaa cagcgggaat tcttcgaatc aaacaaaccc
    21781 atctggatcg aataacaatg gaaatactca gagagaacca aaccatccaa acaatggttc
    21841 atcgaatggc ggaacgaaca atgcttcatc tcgtccaaat acagcaaatc aaagcggtat
    21901 agagaatcca tcttctgctt cttctgattt tgttgtaaaa tcaccaattg atgctgtatt
    21961 gcctacaaat acaacgaatg tccaacaagc aatcgttcga gaagcattca agcatcttgg
    22021 aaaaccatat gtatggggag caaaaggtcc aaatactttt gactgttctg gtttgactta
    22081 ttacgtatat atgaaagcaa ccggtcatta tatcggtggc tggacaggcg aacagcaata
    22141 tgcaggtacg cagattccag taagtcaggc ccaacctggc gacctcgtct tctggggacc
    22201 ttcttccggt gttactcacc atgtaggtat ctatattggg aacggacaat ttatccatgc
    22261 gcctcaacca ggagataaag ttcgagtaac ttctatttca gatttcacgc ctgattttgc
    22321 tgtccgagta aacttagcag gtttacctgc tgcttcaggt tcgctgacag gcggctcatc
    22381 tattttagat ggattagatg gctcgttcca tttcagtcaa aaccaaacaa ctgatcagtt
    22441 cttgaaaaag attgcagatg atgcacagga aatcgggcaa aaagaaggaa tctacgcatc
    22501 agtcatgatg gctcaagcta tccttgaaag tggatctgga aacagcttat tatcaagcga
    22561 accaaatcat aacctttttg gtatcaaagg atcatataaa ggaagcagcg tgaccttcaa
    22621 tacacttgaa caagatagtt ccggacaaag ctaccaaatc cgcgcacaat tccgtaaata
    22681 tccttcttac aaggaaagtt tggaagacta tgccgacttg atcaaaaatg gactgactgg
    22741 caatcctgat ttctacaaac caacttggaa gtcggaaaca aaagactaca aagaagcaac
    22801 caaatatttg gaaggacgtt atgctacaga tcgccaatat tcacaaaaat tgaacgcgat
    22861 catcgaagcg tacgacctga caaaatatga tgaaccgaaa aaagaagcag caacaactga
    22921 agaagcaaac gctgaaatcc tcaatatgtc taagcgattc gatgtgccaa tcaaatggac
    22981 aacagatggc gtgccaatca caggattaga attttcaacg ataaaacgcg tcaacaacgc
    23041 ttcttccatc ttccgtgtcg cttcaatctg ggatttgtgg aacaatttta cggcaagaca
    23101 gataccagaa acaactactc gtacagttaa agctgcaact gttcctgtac taaccttgtt
    23161 aagtttagac aaatcattct ggcttgatct gcctttaaag aaatagaata aattaaaaag
    23221 gggatgtgac actgtcacac tcccttttta atttattcta tttctttata tttattttgt
    23281 attccgttac aaactcgcgt acttggttag gttccagagt gacatctcca aaactttcaa
    23341 gtcgctccgc tcctggcagt tcttgagtct caaatgtgat accgccatga tttactaatt
    23401 tattcccgcg catttccggt ccatcttctc caaaatttgc tgtaaaaatc acgattcctg
    23461 aagcatctgt ttttacttgg atcgatactt tttcatctgg gcttgtcaat tccgcagcat
    23521 ttagtaaacc agattgtttt ttcaacaaaa atggatgatc gatgccgccc actatcattg
    23581 attggcgaaa atcactggca aagacctcac ctaatttttt aggacgttgg aagtcaaatg
    23641 ctgtgccact tactgaaact acttctcctg taggcgttgt atctttattg agcgtagcaa
    23701 ataatcggct attcaaccaa agtatatgtt cgtcgattga ctgtgctgga tcaccggtta
    23761 aattgaaata gacatgattt gtaggattga atactgtttt gcggtcactg atcccttgga
    23821 ccgtcactcg ccatgtatca tcgttcgtca gcgtataccg tacttctaca tctaaagttc
    23881 caggaaatcc gttttccata tctgggctag tctgatagaa aatgaccgat gcttcgtttt
    23941 caccattgat gactgtataa tgccactgct tggcttcaaa gctaggtgca ccaccatgta
    24001 aacaatgacc agtgtccggg tctgttttta cttcgaacgt ttcatcatct aatttgaatg
    24061 tgccattcgt aatccgtcca gccatacgtc cgattgaagc accgatataa gggtcttttt
    24121 ctagatattc ttttgcttca tcaaaaccta agatcaactc tcgtttttca ttatcgatta
    24181 ttgtttgaaa atgaacaacc cgtgccccaa gatcactgac agacaaagat gtcccatttt
    24241 gattcgtgat cgtaatcaag tgatagtttt cgccaaaatt ttgttcattg atttccatgt
    24301 tccttgcacc ctcttttctt tcatttgcac tgattccagc atacatggaa accgttttct
    24361 taacagctta ttccgtgagt aacgagaaaa aatttactat attctaataa aagaccgtga
    24421 aaaaaaggtt gtgacaaaaa tattgtcaca acctcttttt ccgaacaaac ggtgttcaaa
    24481 agcttgcatc tgcggtaata agcccaacca aacgaaaaat atgaggagct atttttgctt
    24541 ggctgttctt attacttgat gcaggacagc tttttcacaa tctctttttc aatacgattc
    24601 cagtatataa ccatgtcgtc agtacatagt agatgaaata caatacgaag aatatcgtaa
    24661 acggaaccca aatatctttg tatggatttt gcatgaatag accaaacatt tgtaatccga
    24721 ataagacatg gactacacct aagattcctg gtgctaagaa taacacgcct acttctctac
    24781 ggatcgattg tttaagcaac ccgcgtcgtg ttcctatctt ttcaagcatt tcataacgag
    24841 caatgtcact cttgcttcct gacaagatct tgaacatcaa acagctagca agcatggtca
    24901 agaaagctaa acctaggaag aatcccataa attcaaaacc agagaataga ccattataca
    24961 cttcatacat ttcatatttc tggttgctgt actctacttt ttgcaaagat ggattgttca
    25021 ttttattttg agcaacaagt gtttcgattg gtttcaggtt tgcttggaag tcttttacct
    25081 gaactagctg taaagtggat tgtggcaagt tcagttgatc aaattctgat tgactgacta
    25141 ccttgatttc tttttcttgc tgttccggca attcatagct tcgaagttcc tcttgtacag
    25201 tcagttcatt cattttttta gcaggaactt tttctttcgt gatcttcggc ggtgttccat
    25261 cttcatgttt tatcatgatc aatggttgag ccgcaaattc acttgcatta tagtaaatcg
    25321 ttcccgcatc ttctttttga gtataagaag cagaaagtgt tggtgaaagt tctttgattt
    25381 tttgctgatc ttctgcccga ggattattca tcactagatc atatccagaa ttgttttctg
    25441 tcaagtctgc aatttcattt ttaaaaccta atcctaccgt caaagcgccc agtgccaagg
    25501 caaacagcat agcgaccatt gagagcattt gtgtatattc acgaatacga aagtttaact
    25561 gtgacaatgt gaaattgttc aattttttca atgaaatctg ttctgatttc tttagtaatg
    25621 ataaaaagaa aatgatcaca gaatggaaaa tgaaataagt tcctaatacg atcgtaacta
    25681 aggctacccc tataccaaag acttgatagg tccccacgtg tttcatcata tagtaaccgc
    25741 agcctagaaa agcaattccc agtactactt caaggaaaaa caagaattta tgctgcttga
    25801 ttcttgttgg tgtctgatcc gcacgaatca atgctaaaat cggttttttg acaatcgaaa
    25861 aagcattgac aacagcagct aataaaaaca aaacagcaaa aaacaaaaca gtgatcaaca
    25921 acccgtgaat actaaaaggt gtaaaatgcg aaatattgag atctaactga tccactaata
    25981 atcggtggac gatacttgtc aatcctacac cgacagctga acccactaaa gtagctgcga
    26041 tccctactaa gaatgtttca gaaaaaatca tctgtgcgat ttttctgcct tttgctccca
    26101 gcatcataaa cattgcatag tctttttgcc gcatcgtcat caaaaaggaa tttgcatata
    26161 aaatataaac gaatgtgatg atccctagta aaacagaacc gaatcggaaa atgataactg
    26221 tagccgcaac gatcgtatta cttttcaaaa aagcttcgtt gcttgccatt gattcaaaca
    26281 tgtaaaaaat agcagatgcc ataactaatc ctgagaataa caccaagtag tctcttaaac
    26341 ggctcttgat cccagtaagt gataatttcc aaagcatagt caatctcccc ctactgttcc
    26401 aagtttccaa gaatagatag tatttctcga tagaaggaat cacggctttg atctccacgt
    26461 ttcacttctt gatggatacc gccatccttg atgaataaaa tacgttggca ataacttgca
    26521 gaaaacggat catgcgtcac aagaagaatc gatacatgat cttttgtatt caattcgtcc
    26581 atcgtatcta aaagatcccg ggcacttttg gaatccagcg cacctgtagg ctcatcccct
    26641 aatagaatcg ttggttgtgt gatcaatgca cgtgcggcgg cgacccgttg tttttgtcca
    26701 ccggaaatct cagaaggata gctttccaaa atatgagaga tggataaacg ttctgcaatt
    26761 ttttggacac gttgcttgat ttcttttggt ctgacgcctt gtaaagaaag aggaacagcg
    26821 atattttctt gtgctgtcaa gctttctaat aaattgaaat cttggaaaat aaagccaatc
    26881 tcattcgcac gaaaatctgc tagttgattt ccttttaatg tggtcacatc tttttgattg
    26941 attcggatat gcccatctgt tggtttatct aatgtggata aaatattcaa aagtgtcgac
    27001 ttaccagaac cagaagcgcc catgatccca ataaattcgc ctttttctac atcgaagctg
    27061 atgccgctta atgcttgcgt ctttttctca ttgttttttc cgtatacttt tgttacattc
    27121 tgtacttcga ctattttgtt catttctttc cctacccttt aattagtttt tccagtgctg
    27181 ttttcggcac gtcttttttt tcgacttctt catacgaagt gacaccttta tttttgttcc
    27241 aggtgatttt taaatatgct cctttacgaa gcggtcgagt caattgtccc ttgaagtcca
    27301 gttctttttc cttaccctct ttcgtatagc caggcaggat atatctatag ttgactgttt
    27361 cttgtccaga gtctgatttt gaaactgttt ttgtaccatc tgtcgtaatt tgtacatagt
    27421 attcttctcc acccataact acgtaatctg cgattttcac ccctgcaagt accacaacga
    27481 tgaaaacaag tagaccgatc agaagttttt tcactttttc cccttctctc ttactttata
    27541 tactgattat agaaaaaagc gaacaattct gccttcgaat caactatcat tcttctttca
    27601 attttgtcat tttctttaaa acaactaaaa aaagagttca agacaataat ccgtcctaaa
    27661 ctccttcttc ctatcttaca aaaagtatgt cacttacggt ctttcatgtc gcctgtattg
    27721 ataacaggtt gcgttccttt gtctgtaatg attgagacaa gtaaattatt gatcaattgg
    27781 actttccgat catcggtgaa attgatttct tgtccatctt cgatttgctc taaggccatt
    27841 tgagtgattg tgacagctcc ttcaacaatg gtttgtcgag cagacaaaat ggcttttgct
    27901 tgttgacgtt ggagcatggc actagcgatt tctgttgcat aggctaaatg gttcaagcgt
    27961 gtttcgatta cttcgacacc tgctactgct aaacgctctt gcagctcttt ttgcaactcg
    28021 tcagacactg ccgtcgtgtt tcctcgaagc gtcaaatcat tctcattgaa tgtatcatac
    28081 gggtattggc tagcgatatg ccgaatggct gtctcacttt ggatttctac aaaatcttga
    28141 taatacgcta catcgaataa tgcctttgct gtatcaacga ctttaaagac tactactgct
    28201 gagatttcga tggggtttcc atccaaatca ttgactttta aaacagaact attgaaattc
    28261 cgaactttca acgaaacagt cattttttgt gccaaaggta tcgtaaggaa aaagccattt
    28321 tctcgaatcg tacctaaata ttgtccaaaa aacaaaatta cttttgcttg attaggactg
    28381 actacagttg ccgaacttaa caacaataac gtgatcaacc aaagaaaaat acttaaaaaa
    28441 agtgcccaaa ctttcgcttg ccacatacct aaatagaaga aaaacaatcc aactaaagct
    28501 aatacgacca atccgacaat ccctgcataa ccattgatat aaaatgctct tttttctctc
    28561 atgctacttc ctgcgctcct ttatccttca ataaatatct aatgttactt ttttaatttt
    28621 tttttcgaat acgcgccatt acaccttcta gttctaactc tttgtcttca gtgatgtacc
    28681 aaccgcttgc ctgtgtccct ccggctgcct gcggtaaata atccaatttt gttcgaaccc
    28741 agtgcttttc ttctgtaaaa tagtcttcta ccaagacctc tagatccatc cctgctgaaa
    28801 gaggcaaatc ttcccgaaca gatttaaaga taaatcgttc cttcttccca tcatacttca
    28861 atattcctgt atcgataatc ggtaaagaat aataatccag ctctttcttc accgtcaata
    28921 aatgtttgaa aacttcatgg tacacttgct ctaattggcg accttctgaa ttgttcgggt
    28981 aattaaccat cactttttct ttgtctggat catagaaggt ttggcttagt tgagtgatat
    29041 aagtatgtaa tctttccatt tctgttttta acttttctct ttgaccttct tctaccttca
    29101 tatactcttt caccctgttt tctttttaga tattttcttt cttattttac tatagttatg
    29161 tgcgttaagc gatgaaaaac agcaaagatt ggaaggatct ttgctgtttt ttcttaaaat
    29221 atccagttga gtacaggatc aatctgtttc attgtcctct tgatccgtcg taatattgat
    29281 cgatgtgtct ttagcagtga tctttagctt tttctgtcct tgttctaaca aagtatttgt
    29341 tattggctgg tagtcttttt caatataaga ttcaccagac gtttggatag tatagccact
    29401 gttttccatc tcatgcaaag ataaattgcc accgtttagg atgacttttc cttctttgct
    29461 gatcaaactg tcttctagat ggaagttgct gttttcacct gtgacgatca agttatccac
    29521 attggcctca tctaatcgaa gtgagcctaa ttcatctttc gcagttattg ttcctcctgt
    29581 aaattcattg aacgataccc agccatcatg tgtcttagta ttcacttttt tgattgatac
    29641 ttcgttgata tcaattgcac tattattccc ttcgattgtc aattcagata attcatgatc
    29701 tgcagggaca acaatagtga tttgtgcact tgtgtcttct aaactaatga ttgcacctgt
    29761 tgattttttg actgcattca cagtcaacac gccatttttc tcctttattt ctggcttttc
    29821 tgtcttatca taagtcgttt ttatctcaaa atccaatccg cgtatgaccg aaactgtttg
    29881 attttctgca tggatgacga ttttgtttgc atccttgatt ttttttgtct cagtaaccat
    29941 atcgatcaac cgaggaccat tatcccaagt cagactcttt tgagcgccta atgtataagt
    30001 tgcacctgct aggaggccac cagtaagcat cagaccaata ccggtaatca aaaaatgttt
    30061 caatctcaat ttatgtgtcc tccttcaaac gcccgctgaa tgcagatctc tttttgtaat
    30121 aaaacgtcgt cccatccatt taacaaagtt catcatgaca taaaaaagcc cttttgttcc
    30181 tttcagcaac agtggcgaaa taaatactgc gcttcctgtg gcgaacagac cgacaccgat
    30241 aaagaataat ccactcagaa tcgattgtcc aaacacactg attcctgaga tgatcatgaa
    30301 taggccaaca cctaagatac tgatacataa aacatagata ctaaaaatga gcgctagtaa
    30361 agcaaccaat agtcccccaa taaccaatat aaaccccagt gctagtggaa tgaggacagg
    30421 agaagcaaat aaaccgataa tgattaacca aaccaggcga atttgtcttt ttggattttt
    30481 cactaactcg ttttctgctt gttcttcttc tgaaaagtaa ctgattttta attttaaggc
    30541 aaactgcttt ggtgtaccat attcatcaat gatctgatct aatgtttttc cagaatctaa
    30601 aaaatattcc tcataatact ggatcaaatc aaaacgatcg tcttcaggaa tttcttgaag
    30661 atgatccaca acttcattca aatattcatt catttgtgct ctcctccaat aaccggtcta
    30721 aagaatctcg aaaaacaatc cattcatcaa taatttcttc taaatgacga cttcccattg
    30781 gtgtcaacga gtaatatcga cggtttctgc cttcaaaagg ttcatcatag gtctcaagat
    30841 atccttcttt tttcaatctt ctcaaaaccg gatatagtgt agattcactg acagagagac
    30901 tttcttgtac gatttttgtt aaggcatacc catacatatc ttccttgctt aatgctgcta
    30961 gcacagtacc atcaagaaga acagttggaa tctggatgtg cattacgtca ccttctattc
    31021 tcaagtgtaa tattttattt caatctatat tatacaacat ataatatagt ttcaaaatca
    31081 gtttgtcaaa tacaaaaaaa ctgactaaaa gatttgatcc tttttagtca gcaaaaaatg
    31141 gcttctcttt gatttttatt ataacagtgg cataatccaa tttgtccaca tccagctcag
    31201 tggcatgata acgatcattg caggtatcat gtcagctact gggaacattt tcacgttgat
    31261 cattctaaaa ccggtagcga ccatcaagaa tccgccgcaa gctttaaaat ctaagatcat
    31321 gtctggtgta gtcaatggat aaataaattt tgccaataag aacaaaatat aaaaaaaaat
    31381 gaattgggga attgctatca cagaaacgac ataccctaaa ttacacgcaa aaatagctgc
    31441 tgtgaaaaaa tcaaggacag atttagaaat caaaatcgta ctgtctcctg tcatcccaga
    31501 atctaaactt ccatagatcc ccgtaccact tgcacaaaat agaacaatga ccgtcactaa
    31561 tgtgctgata aattcatcgt gggtcatacc aagcttttca ctagggaaga ttttagaaat
    31621 aggtacttgc atcagcgcag cccccttatt tatcccatta cctaaatgaa caatcaaacc
    31681 aatcgctgtt cctatcacta aagcaaaaat aacagccggc atatttttca tcggcgcaat
    31741 ggaatagatt cccatcccca tcgaacacac accaaaaacc atcgtcagct gtgctttaaa
    31801 atgttcactt aatttatttc ctactaatcc gccaattagt ccgccaaaca aaacggaacc
    31861 tacattgatc aaaactccag ttggcatcaa aaaactcctc tctttttcta cgaagcgaaa
    31921 aaaatcagaa aaatttctgt aattattgct ttcgctgcaa gaaagattgt aacagacaga
    31981 gaagattaca ccaattcatt ttttgtgtta aagtattctt tattggaata agtaggagga
    32041 atatgatgga tatccataaa ttcgaagttt ttcttgattt agccgaaaca atgaatttca
    32101 ccaaaactgc tgatcgacaa ttcaccaccc aaggaaatat ttctaaacag attctttcgt
    32161 tagaaacaga attagacgtc aaattattcg aacgcgccca tagaaaaatc gaattgaccg
    32221 aagctggaag cttattgctc ccatatgtaa aaaatgtcgt agaacaatac catgctatgc
    32281 aagaagtgct tgaaacctat acgaaagaca acaatctttc attaaatatc ttaacgatac
    32341 cgacaatgat caattataaa ggtttttcca aaatcaccga gtttttgaaa cgccatcctg
    32401 aatttacagt ccagttgaaa gaagtggaaa gtgtcgaatt aacttacaat gacgccaatg
    32461 aacatagtga cacgatccac tttgctagaa gtttccaggc cccaccaagt tcgattgagt
    32521 ggttgcctac tgaaacagac gattttgtag cagttctacc taaaaatcat cctttagcta
    32581 gtaaaaagaa attggatcta agcgaactga aaaaggagaa ctttttgctc cttggcccca
    32641 ctacgaactt gtatcaacct gtactagatc tgtgtcgcga agctggattt gaaccaaaaa
    32701 tctcttataa aggagcaaga atcgacttga tcatcaatat gattgcaaat gacatgggga
    32761 ttgctattgt tatggaaaaa acagtcaaga atctattaaa agaaaatact gtgattctcc
    32821 ctatttctcc aacaacagag agttatcttg catttactcg taaagtcggt gagcattctt
    32881 tggcttcaga tacattttgg gagtatttaa atcaagaaga aaactaagcc ctacattttc
    32941 tgtccatcta tccacccaaa aaaagagagc gacgcatgac tttcgctctc tttcttgcat
    33001 catgtccttg tttcaatgac acctctaaca tttctcgtag ttcaataaga aagcagcgat
    33061 ttttatgcca aaagaaccgt aagaacattt ccctaatcac aaaaaaacga ctaaaaaccc
    33121 ctaaaaacct tcaatagaat ttttaggggt tttattcttt ttcctattgt ttacttaacc
    33181 gtatcattgc tgtcgttcct actccttcga tactgctata atcaatacgt ccatcatgca
    33241 gttctagaat ttttttaacc agtgaaagtc ctagcccatt cccagaaatt tgacgacttg
    33301 tatctccttg ataaaatttt tcaaacattc gatctctggt ctcttcattc attcctacac
    33361 ctgaatcggt cacttccagt acaatctctg tggctgtctc aaatagtttg atatgaatct
    33421 gtccattgat ttgattgtac tttatggcgt tatccatgat attcagccac acttggtaca
    33481 aaaactcttc attgcctgtg taatttactg cagcaagttc gatatccaat tctagctgtt
    33541 ctttctccca tttaggctga aaaaaaacga ttacttctct gatttgttca tctaatcgat
    33601 actctttctt ttccagttgg atacgctggt tttccagttt gttcaatttt aagatgttct
    33661 ctgttaattg tgaaagctgc gtgatacttt cgataatccg atataaaaat atttggcgtt
    33721 cttcgtcaga gagatttggg gcttgtaaca attgaacata tccttggatt gttgctagtg
    33781 gtgttttgaa ttcatgggat acactggaca caaagtcatt cctcagtgtc tcgatactat
    33841 tgagttcttg gaccataacg ttgaaatctt tatacagttg ctgtacttct gctactttct
    33901 gctgttcatc cattcgaatc gaaaaatctc ccgttgctac cagactcata tttgtcccta
    33961 gcgcactgat tggatgcagg atacgccgcc caacaaaaat cgatattcct gtacccacga
    34021 ccatactgaa ccccgcaaag acgaataacg ggtataacgt tggttttcca gccgattcag
    34081 caggcgagat agaatgtcga gacaataaga aaataaaacc gagaaaacac agcagtgtca
    34141 ctaagatcga aatgaagaca atactagcaa aatagatcca taattgtgaa aatagctttt
    34201 ttttcatctt taaataaccg ccttatagcc tagtccccgt actgtgatga tttgaaaatc
    34261 ttccgtcttt tcaaaacggg tccttaaacg tttgatatgt acatcgatcg ttcgttcttc
    34321 tgtattcgta tctaatcccc aaatatcatc catcaactgt tggcgagtga agatcttgtt
    34381 gggataagac agtaatttat acagaagcag aaattctttt tgaggcagaa tcaacgaatg
    34441 ctgatcttgt aacactgtat aagcatctag ctctaatttt gtttgtccga ttatcaagct
    34501 actgctgtaa ttgatctttg aacgtcgaag caatgcttcc acacgtagga tcatctcatt
    34561 gacatcgatg ggttttgtca tataatcatc tgctcctaat ttgaacccgc gtttcttatc
    34621 ctcaaaatcg gcctttgccg taatcattag aacaggtgtg tcaaatctgg tgctacgtaa
    34681 tgagtctagc aagtcatagc catccatttt cggcatcatg atatctgtaa tgattaattc
    34741 tatacgtgtc gcttctagtt ttttcagcgc atcctctcca ttcaatgcgg tgatgactga
    34801 aaagcccgct cgttccaaca cagaacggta aagcaactgt aattgcggat catcttctac
    34861 tactaaaata cgattcattg atctccctct gttttttgaa aaatttctag attttttctt
    34921 gtagttcatc ttcagttaac atttatttcg tatactacga tcattgttct gatatactta
    34981 ttagtatacc gaatatttca atacgggaga agggtgatta tgcttcaatt aaaagatata
    35041 aaaaaatatt ataaagtcgg cgaaaccacc accaaagcat tggatggtgt gtctgtcgct
    35101 ttcagacaaa aagaattcgt agcgatttta ggtcctagtg gttctggtaa aacgactatg
    35161 ctgaatgtga ttggtggact agataattat gattccggtg atatggtaat caacggaaag
    35221 tctactaaag actttaagga cagtgactgg gatgcctacc gaaacaactc tatcggtttc
    35281 atttttcaaa gttacaactt gattggtcat ctaggcatta ttgaaaacgt tgaacttggg
    35341 atgacattaa gtggtgtttc taaagacgaa aaacgaaaac gggcagaaga tgcattgcac
    35401 cgagtcggct tgacaaatca tatgcataaa aagccaaatc agttatctgg tggacaaatg
    35461 cagcgagtgg ccatcgctcg agcactagcc aatgacccag atatcctttt gtgcgatgaa
    35521 ccaaccggag cgttagatac agaaacaagt atccagatca tggaattgat ccaagagtta
    35581 tcgaaagaaa aattagtgat catggtcaca cataatcctg aactggccca tcaatacgca
    35641 gatcgaatca ttgaattttc tgatggtaag atcttaacag attcccatcc tcacatcgaa
    35701 cgaccaaaag atgatcaatt taacttacgc agaacaaaga tgagtttttg gacagcgtta
    35761 aagctttcct tcaacaatat ccgaacaaaa aaaggacgta ctttcttgac ctcctttgct
    35821 tccagtattg ggatcatcgg aatcgcgatc gttctgtccc tttcttctgg attccaaaaa
    35881 caaatcgata acacgcaagc tgaaacgatg gcgaaatttc cgattactat ttctaaggta
    35941 acgactaacc agactcgtga cgatgccgga ttgggtgcaa gcaaagcgga ttatccagac
    36001 agcaaaacga ttactgcaaa agtcagcgaa gaagataaag cacagcacac gaataagatt
    36061 gatcaaacat acgtcgatta cgtaacagac atcgatccta acttaagtaa taatatcgga
    36121 tttacccgta ctacaggaat caatctttta cgtgatgtaa atggcaaagt acagcctgtc
    36181 agcttctcga atcaaaatcc tgatacggaa tctctttctt tatctagtac gatgtcagca
    36241 atgacaggtg tgggagtgtc aagtttccct acacagcttg acactagcaa agaaaacttt
    36301 ttaaaagaca attattcttt acttgccgga agttatccag cctcagcaac agatgtcgtg
    36361 ctgatcgtag acggcaataa taatactaat atcaacgcat tgaagaatct tggatttgat
    36421 gtgaaagaag acgaaaaact tgattttgat gatatcgttg gtacaacatt caaattagta
    36481 aacaacaata cttactatac aaaacttcca actgggaatt ttatccctaa tacagattat
    36541 gatgcgatgt atcagaatgc ttctgatgaa ttgaagatct cggggatcct acgcgtgaaa
    36601 tcttcttcta caatgaatct cttatctcca ggaatcgctt atagcgatca attaacgact
    36661 caaatcgtca acgaaaacaa agaatcagaa atcgtcaaag ctcaaagaga cagtggtgta
    36721 aatgtcttaa ctactgaaaa agttgacgaa aatgccaaac aaacattgct tagttattta
    36781 ggtggagaca gcttgccttc aagtatcatg atttatccga acaattttga agacaaagaa
    36841 aagatcttgg attatctaga tgattacaat aaaggcaaat cagatgaaga taaaatcatt
    36901 tatactgatt tagctggaac gatgactgaa ctgactggcg gattgatgga tgctatcact
    36961 tatgtcctta ttgcttttgc agggatctct ttagtaacaa gtatgatcat gatcagtatc
    37021 attacttata catctgtgat tgaacggaca aaagaaatcg gtgtactaaa agctttaggt
    37081 gcacgtaaaa aagacatcac tcgcgtattt gacgcagaaa cgtgtatttt aggtatttct
    37141 tctgggatat taggtgtgtt tattgcatgg ctagctacgt tccctatcaa tagcatctta
    37201 tacaacatga cggatctaaa aaatgttgct caactaaatc ctgtccatgc gattattcta
    37261 gtgatcgtct ctactatatt gacgatgctt ggcggtcatc ttcctgcacg aatggcagcg
    37321 aaaaaagacg ccgctatcgc tttgcgtgca gaataaggtt gtgacaacca catttagatt
    37381 tgagtcataa gagcgctgaa atagtagaaa acagcaagaa acgaggaagt aatatgttcc
    37441 ttgtttcgcg ctgttttttt taattatttt ttataattct ggtatacttt tctttccttt
    37501 gtaccacaac tcttctggcg tatacctgtc ttttccattt atgaatactg ttccatctgc
    37561 ttcaatcgtt acttcagtcc caatccacat attacgagaa agtgcgagaa gattttttct
    37621 ttttcctctt cctttttttc caaattgcaa ggcatcggtt atctcttctg tccaatgaga
    37681 tttcacgtat tttacttctc cgttttcaaa tgtaactttc aaaatattcg ctatattttc
    37741 cacttttact gctttaggaa atgactcctc catttttttc actttccttc ctccaacact
    37801 aagtatgcgc tttcttttag tgataagtat atcatagttt attctattat caaaaaaacg
    37861 catccattcc attgtagaat actttaccga acaagttgaa ttgttttcct ctttttcacc
    37921 ttttactata gataggtaaa gacaactaag gaggaatctc tcatgacaga tcaaccgtat
    37981 gatttaagaa aagtcatcga agaactaaaa acacttccag gtcaatatca cgaaacagat
    38041 attgaaatcg atcctgaagc agaattatct ggtgtttacc gttatatcgg tgctggcggt
    38101 acagtaaaac gtccgactca agaaggacca actatgactt tcaacaatat caaaggtttc
    38161 cccggcacac gtgtgaacat cggaacaatg gctagtcgta aacgtgtagg tgaaattttg
    38221 caccatgatt atcgaacact tggtcgtttc ttgaaagacg ctgtagaaaa tccaatcaaa
    38281 cctgtgaaag tagacaaagc agacgctcca gcacaagaag tcgttcatct agctaccgat
    38341 gcagacttcg atattcgcaa cattttgcct gcacctacaa atactcctga agatgctggt
    38401 ccatacatca caatgggtgt agtcttagga tcagatccag aaaaaacaat gagcgatgta
    38461 acgatccatc gtatggttct agaagataaa gatacgatcg gtatgtacat catgcctggc
    38521 ggacgccaca ttggtcactt ccaaaaacaa ttcgaagcct tgaataaacc aatgcctatc
    38581 actatcaata ttggtttaga tccagcaatt gccattggca cgactttcga accacctacc
    38641 actccacttg gctacaatga actatggtgt gcaggagctt tgcgtaacga acctattcaa
    38701 atcgttgatg gtatagcagt cgatgaagtg ggtattgctc gtgctgaatt catcattgaa
    38761 gcagaaatca tgccaaatga aacaatgcaa gaagatatca acacgaactc aggaaaagca
    38821 atgccagaat ttcctggcta tactggggat gctaatccag ctgtacaagt agtgaaagtc
    38881 aaagcagtta ctcaccgaaa agacaatcca atcatgcaaa caacgattgg tcccagtgaa
    38941 gaacacgtat ctatggccgg tattcctaca gaagcaagta ttcttgcctt ggtcgataaa
    39001 gctattccag gaaaagtagt aaatgtctac aatcctcctg caggtggtgg taaattgatg
    39061 accatcatgc aaatccgtaa agaaaacgaa gcggatgaag gtattcagcg tcaagcagct
    39121 attcttgctt tatcagcctt caaagaattg aagacagtca ttttagtcga tgaagatgtt
    39181 gatattttcg acatgaacga tgtagtttgg actttcaaca ctcgtttcca aggagataaa
    39241 gatatcatcg tgatcccagg aatgaggaac catccattgg acccatcaga attaccagaa
    39301 tataatcctg gctctattcg tttccgtggg ataagtgcaa aaactatctt tgacggtaca
    39361 gttcctttcg atatgaaaga acattttgta cgtgcaaaat tccaagaagt agaagattgg
    39421 gaaaaatatt tgaaataatg aatgatctgc aactgttttg acatcataaa aaggagtgcg
    39481 gaaaatggaa caattggcac aacggaagaa aaaaatcgtg attggtgtaa gtggcgcttc
    39541 aggcaccatt tatgccatca acctagtgaa gaaactaaaa gaatatccga tgatagaaac
    39601 acacggaatc atcagtccat gggcaaaaca gaacttaaag ctggaatccg acttatcact
    39661 aactgaattc gaaagcctgt ttgattacca ttattcaaac aaagatttag gtgctgctgt
    39721 cgccagcgga tcatttttga ccgatggaat gatcatcgta ccggcaagca tgaaaacagt
    39781 cgcaggtatc tctgttggtt taggcgacaa cctgattgca cgtgctgctg atgtaacaat
    39841 gaaggagcaa cgaaagttag tcattgttcc tcgtgaaacg ccattaaatg ccattcactt
    39901 ggaaaacttg actaaattag cacgactagg tgtgcaaatc ataccaccaa ttcctgcttt
    39961 ttataatcag cctcaaacga tccaagatct tgttaatcac catacaatga aacttttgga
    40021 tcaatttgaa attgtaaatg agcattcaaa acgttggcag ggtgattaat atggaaaaag
    40081 aaacgatagt tgaagtaacc aaactaggtt tcacgatcca agctgctgtt aaagtaatcg
    40141 gtaaagactt attgatcact ttaacaggcg gagatacacc acatatcgga acagtcacta
    40201 cattttctcg tgatacagag atgcaaactg tacgtttccc tagccacgat ggtcggttcc
    40261 ataaagacga tgtcttagcc gaaaaaatag ctgtgatcat caaaactgcc gttccgggaa
    40321 gttgtacgat cacttccggt atccatgttg accatatctc caatgcacaa atcaacgcct
    40381 cttttccgat gtcagaagag ttaggttaca agattttaga ttggttggaa aaaatagatt
    40441 tccatatcaa agaaccagtt tattataaag atggtgaaaa accattatga aagaagaggt
    40501 tgtgaaatca gcgttatgac ctgagtatga gagaaaaaaa tggaaaaata gcttctcata
    40561 ttttgccgtt tttgagctaa taccgaggga cagctgattg aacgccgttt atcaagaggt
    40621 tgtgataaag ccgcttcgtt tcgagtagta agaaaaattt tgtaaacatg ggtttccaca
    40681 tttttgcata aatttgactt actaccgaga aactggcttt tgaacaccgt ttatcaagag
    40741 gttgtgacac gtcttttgtc acaacctctt ttatttttgc ttcactgtaa ctgctacaat
    40801 atcaccgatt tcttttccga tgtttttacg aatatctttt cgtagtccaa ggatgtagca
    40861 gactgaacca tctggatttt tcacgcccat attcacgata ctgccttcat atggcacatt
    40921 gtcaaaagtt gcttggactt taactcttcc agcaccgaat tcttttctta tatcatacgg
    40981 aaaaataata tatgccccgc ccttgccgac ttcggaagca tagatttttg attcaaaaga
    41041 ataaatttcc ctcattttat ttctcctatt ttttacatct agtatagcat agcaaaaaaa
    41101 agaaggaact gtgacaaaag tcttgtcgca gttccttttt tcgaataaac ggtgttctcc
    41161 tgccaactcc tcggtcacaa gtcacaatag tcaacaaaca tgagaagctg ttttttgaaa
    41221 ttgctccttg tgactcagag ttaaacggca ggctcacaac ctcttcctta aacggtgttc
    41281 aaaagcttgc atctacggca ctaagcccaa tcagatgaaa aatatggagt gctattttta
    41341 tctgattgtt cttactgctt gatgcagagc agctttttca caacctccta catggtgttc
    41401 aaaatattat tcgccttttg cttctttcac taattttgcg aatgcttgtt gttggaattc
    41461 agcagctaag gctttcgtac gttgttcttg ctctgctttg ctcatttttg gattttcagt
    41521 cattgctttt accataccgt cttgaacata agcttttgct tcactttcca tcgtactttg
    41581 ctgtttcttc actaattcag ctaacttggc tgcttggtcc gtacttaatt ctacccatgt
    41641 ctctgggatt ttgaatgtat tcactcggct gtcatattcg tgattgttat cagcaatatt
    41701 gaaccagaat ttatacatgt cgtttttgta ttcccaataa gtagttttcg tcactttttc
    41761 agcatcgccg tctgtctttt ctactttatt tgtttcgtta tccgtaccag ttgcttttgg
    41821 tttttcttgt ttttcatttg ttcggtaaag atacactttt tcttttccat tccctaaagc
    41881 tttatacaaa agcatatctg ctccttggga atcagcactg gaaacaattt tttctgtttt
    41941 tgtttccgtt actttttcca ttccaaagtg attggacaaa ttagcgacga tcaaacttag
    42001 tgaagcgacg aagattagtc cgaaaatcaa agataaaaag gtttgccatg tttttttagc
    42061 gaacacgttc gttaaagcaa aagcaagcaa gctgacaatc aaaactccaa taatcatgca
    42121 ttatcccccg ctttcattag aacaggttct tttttcttca ataaaaaggc aataataaag
    42181 ccaagaatcc caaagatgat cgctacgata aacgcggcat ggtaacctga cagtgtggca
    42241 ttgattgcct gatctttata agctaatggc gtattatcca atacagattt gcttgggata
    42301 tttgcttttg tcacattcgt caacacactg atcaaaatag ctgtaccaat cgagcttgcg
    42361 atttgacgga atgtattatt taccgctgtc ccatgactga tcaagttatt tggcaatgca
    42421 ttcataccag aagtcgttac cggcatcatg accatggaga tcccaaacat acggatcgca
    42481 taaaggatca cgatatataa aactggagtc gtttttgtca agaaagcaaa tggtgcagtt
    42541 gccgctgtca aaatgaacat ccctgtgatg gctaaacgtt tcgcgccgta tttatcgaaa
    42601 atcgcacccg tcacaggcat catagccccc atgatcaatg cacccggcaa caacatcaag
    42661 ccagaatgga atgctgattc tccacgaata ttttgaatat acaatggtac gaccatttct
    42721 gcccctacca tcgccatatt tgttacacca gctaaaacag ctgcaatcgt gaatgtagat
    42781 gatttgaata cacgaagttc caagaatgga tgttccaaat gtaattgacg ccatgagaac
    42841 aaggcgatga aaatcacacc aacaactaag aaaccaatta ctttcaagct tccccagccg
    42901 tcatctccta cactagaaaa tccgtaaagt aaactaccga atccaatcgt tgataaaata
    42961 gcggataaaa tatcaatgct aggatttgac aatggaataa cacttttcat taggaagaat
    43021 gctaaaacca agacaagaac aacgattggc agtaccatac caaacaagtc acgccaatgg
    43081 tagttatcaa tgatataacc agataatgta gggcctaaag caggagcaag tccaataacg
    43141 atccctgaca tccccattgc tgatcctctt ttttctggcg ggaaaataga tagcatgata
    43201 ttttgcaata atggcatcga tactcccaca ccgcaagctt ggatcaaacg accgattagt
    43261 aatgtactaa aattaggtgc tgtaaagcaa gtaatcgttc cgatcaaaaa gatcgtcatg
    43321 gcagaaagat ataaatttct tgaactgaat ttattgatca gccatgctgt tattgggatc
    43381 atgatcccgt tgactagcaa gaaaccagtc gttaaccatt gcacatcaga cgctgaaata
    43441 tcgaaagctt tcatcaatgt aggaaaagct gtcgtcaata aggtctgatt caaaacggta
    43501 caaaatgtac caattaataa gacaacaact aaaagtgtcc gattatatgg ttttccgtaa
    43561 atatctacgg gttggttgtt actcatattt ctccttcttt ctgaattttt tctgaaacta
    43621 ctagaatact ttagtcctaa attcgctatt tgtcaaccta cttgacacat aagttaatac
    43681 ggatataatt aagggaagca agaggacaaa aggagtgaca aaaatggttg gggcttccct
    43741 taaacgtttg ttggaaaatg atcaattggt tgttggcatc agtgaattaa gtgatatcgt
    43801 aggtgtgtct ccacgtcaat taaggtattg ggaacaaaag ggattcattc gttcgatcga
    43861 agctgatgcg aattgtccta gaaaatatcg tttacctaca gtcataaaag tagaactgat
    43921 caaaaaatat ttagatgacg gatttacttt gtcaaaagct gcagaaaagg cagaaatccg
    43981 ccaaaagaaa atgcaccatg tccgtaaagt tttttcaaaa gcaatcaaag atatcgaatt
    44041 gatcgacgaa cgctatacga ttttacaaat cggtaacttc aaagaagaga atgctaagat
    44101 gtacatcatt catgacaacg agacagacga attaacttac aagctccttc ctgtcgatga
    44161 aaaagctgac tacgaacagt tgttaaaaga actctaaacg ccactaatct cctaagtacc
    44221 aagcttttta ataagtagat gctacataaa tacttgaaaa aaggcctgtt tgaacataag
    44281 aatatccgaa cggtgatctg cgtttctttc atatagaaag gaattctcca tcactgttcg
    44341 gatatttttt tatttttttc ggttactttc ttctaataca tctgttagcc aatttgcata
    44401 ttctgtttcc cgattgatcg catgcgctaa aatcaggtag tgtccgtaat tttcatgttt
    44461 ttctttttca gtaggaaaga tcgttttttt tcgctctaat agatgaagtc gtttttcttc
    44521 atgaaggtca cgctgctgct gaataatttc tactaatgcc ggatcattca cgtctttgac
    44581 gaaatacaat ttcagaacaa attcgtctcg attaaccggt agttcattgg tgggtgtatg
    44641 aatccactct gccaattgtt ccttcccttc ttctgttaat tcataaactt tcttttccaa
    44701 tttttcacct gtgatctcta cttgatgctg aatgattcct tgctcttcca tttttgcaag
    44761 ttcaggataa atctgactat gttttgcttg ccaaaattct cctatttcat ttttgaacga
    44821 ttgattcaat tcatatcctg tcatcttctt cttacttaat aaccctaaca aaatatatcg
    44881 aagtgtattt tttcttgcca tcagttttcc ctccttgaca aatctttaaa tccattctat
    44941 cataaatgag taatcgaaaa catgtagttt attacatgtt ttaatttata aggagatgct
    45001 taaacatgaa agaatttaaa gaattggaag attttattgg aactcacttt atctatacgt
    45061 atgacaatgg ttgggaatat gaatggtatg ccaaaaatga ccatactgtt gattaccgta
    45121 tccatggcgg aatggtcaaa ggccgttggg taaaagacca agaagctgat atcgttaaat
    45181 tgacggacgg cgtattcaaa atcacttgga cagagccaac agggacagac gtggcattgg
    45241 actttatgcc aaatgaaaag aaacttcacg gaatgatctt tttccctaaa tgggttgaag
    45301 aacatccaga aatcactgtt actttccaaa acgaacatat cgcagaaatg gaagcagctc
    45361 gtgaaaaata tgaaacttat ccaaaattac ttgttcctga atttgctacg atcacttata
    45421 tgggtgatgc aggtatagac aatgaagatg ttattagcga agaaccatac gatggaatgc
    45481 cagatgatat ccgtagcgga aaatacttcg atgaaaatta taaacgagta aaataaggtt
    45541 gtgaaagaga ggttgtgaaa tcagcgttct gacctgagta ttagagaaag aaacggaaaa
    45601 atagttcctc atgttttgcc gttttttgag ctaataccga gggtcagctg attgaacacc
    45661 gtttatcaag aggttgtgaa atcagcgtta tgctttgagt aataagaacg ctagttagaa
    45721 aatagctttt catattttct aggctagtgg gcttattacc gagaagcagc cgtttgaaca
    45781 ccgtttatca agaggttgtg aaatcagcgt tttgacctga gtattagaga aacaaatgga
    45841 aaaatagttc ctcatatttt gccgtttttt gagctaatac cgagggtcag ctgattgaac
    45901 accgtttatc aaagattgta acaactgcat attcacacag ttaaattagt gacttcaaaa
    45961 tgaaataatg ctcccagcaa aaaattaggc tgggagcatt atttcgttat tctgttcatc
    46021 aaaaatcagc gttttgattc catttcatca caagttcctc ctcatttact gcttcatctt
    46081 tttgctgtgt ttgaattgta aaaccttgtg aaagatagaa atgaatagct gattgatttt
    46141 tttgatagac tgtcaaagtc agtgttttat tggtttcttt tatttttttc attagttgcg
    46201 taccgattct ttgttgccgg tattcccttt tcacaaagat tcctgcgata aactgatcaa
    46261 tcaccccagc aaaaccaata atttcttgat ctatttctgc taagtaaatc actgcatctg
    46321 gtaaagcttt cctaacagat tctacttgat tctcccaata agttgatgga atgaattcat
    46381 gagaatccaa gttagcatgc agccaaatcg atagaacaga ttccagttct ttggcagaca
    46441 attttgttgt tgtgcggatc attttttctc tccttactta ttcattgatt ttaaaataaa
    46501 aaccattttt ttgaagctct tttacaagtt ttcgcccctc aaaaaagtat atcttctctt
    46561 gttttacttt tctaatacca aaagaaacag caactttagg atcatcagct gaaacgattc
    46621 gataagttcc accaggcaat tgatccagct tgactttccc atgatggtcg ctttgtactg
    46681 aaaacggcac accatttcta gtaagtgttt ttttcttatg tttcaaaatg aatgaactac
    46741 catttaccgg tttccctgac gaatcactaa taataaatga aaaatcaagc acttttttac
    46801 ttaatctata ctgatagatt agtcgtccga taaacactaa cagtatgact acagctatta
    46861 tcgttcctgc aagaataaac cattgccgca tggttctttc ctgatttcct tttccttctt
    46921 ctttttttac cgattcgtta taaggaatcc gatgtcctgt cactagcaaa cgatgcgtgt
    46981 tgatcatata cggcgtacat gtaagcaagg taactaagtc ttctccttct gaaatcgtta
    47041 gaacagacgt gtcatctggc agtaccactt gtatattttt aacttgataa gccaatttct
    47101 cccccaaaac agtcaaaata aacgtgtctc cgttttctaa acgatctaat tcggtaaata
    47161 accgtcgatt aggtaaaccg ctgtgagcag agatcactga atgcgtcgaa tttccaccaa
    47221 gcgggaaaga ggttccttgc aagacgcctg ctccattttc aaggatccta ccattgagcc
    47281 gatcataaag tgaaatattt aattggatct taggtatatt gatacttccg atcagccatt
    47341 cctctaattg gctggatgtt gtactttcat ttctgttctt ttcattgaaa ggatcagtac
    47401 caggattgaa tccttggtca gttaatcgtt ggtttttctc ctccattttc tttcgctgca
    47461 cttcaatttc agctgcggtc cgtttttgta cttgttcgat acgtttttga tcaataaaac
    47521 tatttaaaga atccacataa aatggatata aagcgatcag taaccctacg acgatacata
    47581 ttaataaaaa caaacgaaac aaaagtcgac gagactgttt ttgcttactc tgcttcacat
    47641 gtgtcctccc ttgcaagttt ttttgttctt tcttttatta tatgggttca ggaaaaaaat
    47701 agaaaatgaa agccgatgag gttgtgaaaa agctgtcctg catcaagtaa taagtacagc
    47761 ccaaaaaaat agctactcat attttttgtt gggttgggct tattaccgca gatgcaagct
    47821 tttgaacacc gtttaaggaa gaggttgtga aaactgcgtt atgctttgag taataagagc
    47881 gctagtcaga aaatagcttc tcatattttc taggctagtg agcttattac cgagaagcag
    47941 ctgattgaac accgtttacc gagaggtcat gaaaaagcta ctttgtttcg agtattaaga
    48001 aaaattctgt ttcaaaacaa ggagatgcaa caaaacttat gtcgcatcct ctctccttag
    48061 aactttcact tatgtttttc ttgtaaaatt cataaatatt ttcatgaatt ttctaatttc
    48121 ttgcctacct ctcgcatagg atatatgatg aatttatcta aagtttgcaa aggagttcga
    48181 caattgaaaa aatatggccc atttttagca atttttttca ttgctttggc atttctcatg
    48241 cctcatttat tcacacataa actaattttg ggtgctgatg ccccattcca ttacaatcgg
    48301 ttctatgatg ccgcgcaaca aattaaatat ggggatttcc attattttcc ttccctttat
    48361 ggattccagc aaagtggcag gatcgtgaat gccgtttacg gcccattttt cgcttattta
    48421 caaggattga tcgtgttgct tgcaggtagc tggtttcatt atcagattct ttcaaatttc
    48481 attctttatc ttatttcagg attttctatg ctgattttac tgagatatgt caatgttcga
    48541 aattgggtaa gtgtaccagt agccgtttta ttcatgagta cgtattctat tcaatactgg
    48601 tctatcaacc aaggattcac tagctggggg acttgttttt atcctttatg tatgatccct
    48661 attgctgatt tcgtccttca taaaaagttc cctgttatca aagtcgctgt ctcagtggga
    48721 cttatgacac agatccattt actgtcttcg atcatgttag ctttgatgta tatccctttt
    48781 tatctttatt acttttttaa ccagactgaa aaaggaaaag cactgcttca actgattaag
    48841 tcggtcttgc tttattttgt tctgacagca aatatttggg caggattagc tattgtttac
    48901 agtgggaata agattcttcc tccctttgtt aacagagaaa tgagtcaaaa ggcgatagat
    48961 ctggatggca gttattggct ccattaccct aaggcctttc ctatattgat attatcaggt
    49021 tttttgcttt ttattttctt tcaacaaaag aacaccttat tccaaaaaat cgtgttgtac
    49081 acaagtcttg ttttcttttt tctttctact agcttgattc catggacgac attgatcgaa
    49141 aaaaatgtgc cttttattag tttgatccag tttccatttc gatttttcgt gccatttacg
    49201 ctattgcttc tactttacct tgccctttca ctgaaccagt ggtctgaaca aaagtggttc
    49261 cgtcttttaa gtatatttgg cattcttatt ttttcagcac agacgatcca gaacttatac
    49321 cagcatctgg aaaagtggga aaatgaaaca tttgtcagtc gacatactta tctattcgat
    49381 acgccggaag aagcaaggaa aacattcttc agcaaagata tgtctaccag cttgttcgtt
    49441 ttccaaaaaa ccacacctga ctatctgcca atctataagg agacaaaaga caataaatac
    49501 gaccggtata acgaagaaat actagaaaac gaaacaactt ttataaaaac acatccaggc
    49561 ggtcttttga caatcaagtg gaaaaacact ggggacaaaa ctgttcatat ccctgttatc
    49621 gtctacgatc ggactgtgct acagcaaaat ggaaaaacat tgactgatta tgaagtaaca
    49681 gatatcggga ccccaatcgt gaagcagcaa aaaggaatca acgagctcac gcttcattat
    49741 caaacgccaa tctatttcta tttcattctt tctcttactt tgattggctg gtttaccttg
    49801 ctatgtttat ttatttatca tagatacaag cttttacgtg cttaggcaaa agggataaat
    49861 acatccgatc aaaaaactct ccaaacggta taatcgtttg gagagtttta ttttaatcag
    49921 tttttttatg ttatatgtta tattttttat tcgttcacat ctaattcgat ttccaccccg
    49981 tagtgatcac tgatgattgg actatcgatc ccatcaaaaa tccgttgata ttttttaacc
    50041 tgcattcctt cagggacgaa aataaaatct atacgcaatt tttctgtatt ttgttcccaa
    50101 ccatctattt tcttttccac agtagctgct tttccttttt cattcgcgac aacatacgaa
    50161 tcttgaagaa gaaggcaact ttctcttaca gtataataac cttgagagtc tactggatta
    50221 ttgaaatcac ctaggaaaaa aagtggtacg cgagtttcca aaaagtagtt ttccaagttt
    50281 ttccactcaa aataaaagcc acttttttta tctgtccacc aagaaaagtg gcagctcgag
    50341 acaaaaatgt cctgatcatc tatctttgtt ttcccaatca agatcttgcg tgtctgataa
    50401 tcttctttct tttgaaattg ggagacggta aggacctgac tttccaatgt ttttttcgta
    50461 agcagtgcat ttccttcttc atatttatca taaccgatgt ggctcatttc ccaactccaa
    50521 aaatactctt ttccgtgttc ctttaaaagc tgaactaaac ggtaggcaaa attatcttta
    50581 cggataggta cttgattctt taccggacag aacttcatta gcttcgcagg ttctacttct
    50641 tcagattcca gtaattggtt gatttcttgt aaagcaatca cttcataatc ttctaacagg
    50701 atcttatctg ctaattcttg caattttttc tctggttctg gctcaagcca gctatgcgtg
    50761 ttgagtgtca tgaatttcat tggttttctc cttgtcttca tttcgaaaca aaagggttgt
    50821 gacaaaattt ttgtcacaac ctctccagca aatagtgttc tcctgctaac tcctcagtaa
    50881 taagctcaat ggaccaggag ctattttttg tttggctgtt tttatcactt ggtgcagggc
    50941 agctttttca cgacctctcc actaaacagt attcaaactg ctgcttctcg gtaataagcc
    51001 caaccaaacg aaaaatagga ggagctattt ttgtttggct gttcttatga cttgatgcag
    51061 gacagctttt tcacaacctc tccttacatt ttaatggagc cgatcacttt accagctgtc
    51121 actgtaccta attgcttgat cactacttct tctactttat cgtttgtaaa tacgatcatg
    51181 atcgttggat ctttttcttc gttttggatc acatcaagat ccatctcagc taatttcgtt
    51241 cctgttccta cttcttggcc ttctttgaca gcaatctcaa aagctggctg attcatttgg
    51301 actgtatcga ttcccatatg gatcaaaact tcgataccat ctttcgtttc cagcccaatt
    51361 gcatgtttgc tagggaaaat acttgtcact tttccagcga tcggcgcaac aacttctctt
    51421 gatgttggaa taacagcaaa gccgtcaccc atcatttttt gtgagaatac cggatctttt
    51481 acttcagata aaggaatcac ttctccagaa gctgcggaaa ctagttcttg ttctatacct
    51541 aagtattgct tactacctgc ttgtccattt cctgtagaaa ccatttctgg ctctggaatc
    51601 tctgctcctg attgcagcag atcttcgata tctgatttca agacatctgc ttttggtcca
    51661 taaactgctt ggactccatt gtctttgacg atcaatccca tcgcccctgc tcgtttccag
    51721 gcttcttcag tccctacttt ttctcgatca tttacactta cgcgtaaccg agtcatacaa
    51781 gcatcgacat ctttgatatt ttcttttcct cccagcaaat gaatgatctg gaccacttgc
    51841 tgatctgctg ttcctgttcc gctgttagat acaacggttt cttcactgtc attgtcgtaa
    51901 tttccgttac gtcccggtgt agcaaagttg aattgtttga tcaagaaatt tgctaagaaa
    51961 tacgtaacaa caccaaaagc gatcacacac aacacgaagt tgataagatc tccacctaga
    52021 cccgctttga tagctaacgg tgtccgagtc agcaattcga tattcccaaa tgaatggacc
    52081 cgcaatggca agatatctgc catcgcaaat gcagcccctt ggatcactga ataaatgaca
    52141 tataatggca cagcagcaaa cataaacatg aactccaatg gttctgttac acctgttaga
    52201 aagacagcca acgctgctga aaaatacatt gatttatatc ttgctttctt atcaggatcg
    52261 acattacgat acatcgcaaa agccattccc atcaagatac ctgaagaacc aatcatttgt
    52321 cctactttga aacgagccgg cgtccagtta tgcaacacaa actcatattg cgacatatcc
    52381 cctgcacctt taagattcac taaatcagtg gcccaagcca accataacgg atcttgccca
    52441 aatacttgtg tccccgcctg tgcgcctgat aaaatctcat acgatccgcc aagctgtgta
    52501 tagttgatag gaatcgtcag catatgatgc aatccaaatg gcaatagtaa acgttctaat
    52561 gttccaaata aaaacggtgc tagaatcggt gcgctttctt gtgattctgc aatccataaa
    52621 ccaaaattat tgattccagc ctgtacgttt ggccacacca cagcaagaat caatgccacg
    52681 attgttgacc ataagataac aacaaacgga acaaagcgct ttccattgaa aaatgacaaa
    52741 gcatccggca attttctata attatagtac ttattataag ccattgcccc gacaaatcca
    52801 gcgatgatcc ctacgaatac tcccatattc aaagctggtg cttccaatac acttgtaaaa
    52861 aatcctttaa ccatgatctt cgtaccgaac agagtgtggg taaatgcatc ttcattcgca
    52921 agcatgtcac ttgtgacacc aaagatagcc ccagtgatcc gattgattaa aataaatgag
    52981 atcccagctg caaatgctcc gcctgctctt tcttttgccc aacttcctcc tattgctaaa
    53041 gcaaataaaa tatgaagatt accaataatt gcccaaccaa tattttcaat tactccgccc
    53101 gttgtgacaa gcggcgtcca atcaggattg atcaagggaa ttgatttccc tatactgatc
    53161 atcaacccag ctgccggcat aactgctacc acaaccatta aagcctttcc aaatttttgc
    53221 caaaactcaa aactaaatat ctttttcatt ccgtttagct cctttacgca atcggtttcg
    53281 ttaaacgtat tatagcgtgc gttttctttt ttgtaaatgc tttatttttt atttttctgt
    53341 ctataccatt ctataaaacc tataatacgt gtgttccctt ctataatttt ctcctaaaaa
    53401 tttatttttt taagcttttt tctatgaaat attttctttt gtctattgac ttgtgcaatc
    53461 ggttgcgttt attatgaacg tataaaacag ctcattagga ggagaaaaat gaaacagatc
    53521 aaacgactat ttgctattga tccatggaaa atcagcacga cacaattaga taaaaaaaat
    53581 cttcgactgc aagaatcttt aacaagtatt ggaaacggtt atatggggat gcgcgggaac
    53641 tttgaagaaa cttactcagg ggaccaccat caaggtactt atttggcggg tgtctggtat
    53701 cccgataaga cacgtgtcgg ctggtggaaa aatggttatc cagaatactt tggaaaagtg
    53761 atcaacgcct tgaactttat cgcgatagat atttcgatca acgatcagct gatcgacttg
    53821 gcttctttgg aaccagaaga cttttactgg gaattagata tgaaaaatgg tgtattatct
    53881 cgtacattca caatcactac ttctactaat aaagtacgca tttccttcga acgttttctg
    53941 agcattgtca aaaaagaatc agcttatatc tatttaacta tagaaatgct tgaaggtagc
    54001 ggaacagtca aactcgtatc aaaattggat ggaaatgttc aaaacgaaga cagcaactat
    54061 gatgaacatt tttggaatga gattgatcgt ggaactatag aagaaatcgg ctatttgacg
    54121 actaaaacta ttccaaacaa ctttgggatt gaacaattta ctgttactgc agcaatgcgc
    54181 catttcgtta atggaaaatc agtcatccct gactatcacg aagatacttt agcattacat
    54241 ggttgcttgt ctgcagaatt atctcaaggt gagacatggt cagtggaaaa agaaattatc
    54301 gttcttacta gtagagatat tccagaagcg cagcaagcag aaaaagctgt ctcagaatta
    54361 acgaaccaga caaacaatta tatccaagca aaagaagagc aaacagcggc ttgggcagaa
    54421 cgatggaagc ttgccgatgt ggtcatcgaa ggagacgaag aagcacaaca aggtattcga
    54481 ttcaatttgt tccaactatt ctctacttac tacggcgaag atgaacgatt gaatatcggc
    54541 cccaaaggat tcacaggaga aaaatacggc ggagccactt actgggatac agaagcgtat
    54601 gctgtccctc tttatcttgc tttagccaaa cctgaagtaa ctaagaatct gctgaaatat
    54661 cggcataatc aactgccgca agcaatccac aacgctcagc aacaaggatt aaaaggcgcg
    54721 ctttatccta tggtcacctt cactggtgtc gaatgccata acgagtggga aatcacattc
    54781 gaggagattc accgaaatgg cgcgattgcc tatgcaatct acaattatac gaattacacc
    54841 ggcgatacgg aatatttgaa aaatgaagga ctggaagttt tagcagaaat cgcacgcttc
    54901 tgggcagacc gtgtccattt ttcaaaacga gcaaataaat acatgatcca cggtgtgacc
    54961 ggcccaaacg aatatgagaa caatatcaat aacaattggt atacaaatac gatcgcagct
    55021 tgggtcttgc gttacacgcg agaaaattat ttaacttatc aaaaagaagc tgctatcact
    55081 atcagcgaag aagaactagc caaatggaaa gatatcgcag agaacatgta cttcccagtt
    55141 gacgaagaat taggaatctt tgtccagcat gacacattct tagataaaga tctcatgcct
    55201 gtatccgata ttcccacaag cgatcttcct ctgaatcagc attggtcttg ggacaaaatc
    55261 cttagatctt gcttcatcaa gcaggcagat gtactacagg ggatttattt cttcaatgat
    55321 acttttacaa aagaagaaaa gcaaaaaaac tttgatttct atgaaccaat gactgtccat
    55381 gagtcttccc tttcgccaag tatccattcg attttagcag cagaattagg aatggaaagc
    55441 aaagctgtag aaatgtacca gcgaacagct cgcttggatt tggataatta caataacgac
    55501 acagaagacg gcttgcacat cacttccatg actggtagct ggttgtcgat tgtccaagga
    55561 tttgctcaaa tgaaaactgc ccatgatcag ttgagattcg caccatttct gccaaaaact
    55621 tggaaagctt attctttcca tatcaattat cgcggacgtt tattgttcat ctcagtcaca
    55681 gatgaacaag ttactttcaa gttattagaa ggttctcctc tagaaattta cgtctatgaa
    55741 cagtcttatt ctttagcgga tcgtctagaa ataacgctaa gaaaggagga agcaaatgtt
    55801 taaaggggta ttgtttgatt tagacggtgt cattaccgat actgctgaat tccattatcg
    55861 tgcttggcga aagcttggtc aggaaatcgg cattacgatc gaccacacat tcaacgaaca
    55921 gctaaaaggc gtcagccgag aagactcact ctctttgctt ttagcttatg gcggaaaaga
    55981 acactctttt acaaaggaag aatttgcaga attagcgaaa agaaaaaacg attattattt
    56041 agagatgatc cagacgatcg aaccaaaaga tgtcttcccc ggggtcgtgc ctttactgga
    56101 ttctttaaaa gaagaaaaaa tcaagattgc tcttgcttct gcaagtaaaa acgggccatt
    56161 cctacttgaa aaaatgggtc ttacacctta ctttgatgct attgccgacc cggcagaagc
    56221 aacaaacgga aaacctgcgc cagatatctt cctccttgca gcaaaagctg tcggactaaa
    56281 agcagaagaa tgtatcggga tcgaagacgc gcaagccggt atccaagcca tcctctcaag
    56341 tggcgctcaa ccaattggcg tgggacgtgc tgaagacctt ggagaggaga tcccgcttgt
    56401 ccctgatacg acttttctta cgatcgatta cttgaaagaa aagtggcatg accatggata
    56461 atccagagat ctccgtcgta ccagttccag agactgaaat aaagaaaatc acattgaaga
    56521 acgactactt agaagtcgtt cttctcaatt acggtgcccg cctgcaccaa atcttcgcac
    56581 cagacaaaga aggaaaatca gaaaatgttt tattgtctta cgatcgtttc gaagatgttc
    56641 taacagacaa aagctttttt ggagcaactg tcggacctgt agccggaagg atccgggatg
    56701 cttcttgggg tgagcataga ttggagaaaa actgcggatc acaccatatc cacggtggca
    56761 cgaaaggctg gtctttccaa ttttgggaag tagaagtttt caaaactcca tcatcaatag
    56821 gtgtggtctt ttacttaaaa gatgaatttt ctacctatcc aggaccaatc actgctacga
    56881 tcacttaccg tttaacaaaa aacgaattag agatgacaac ctctgctagt agccttgttg
    56941 aaaccatctg caatccgacc aaccatgcct acttcaacct ttcaggaaat ggaacaagag
    57001 acatctatga acatcagtta acggtctttt tagatggtgt gcttgaatta gatcaagaaa
    57061 aactgcctac tggaaattgg acaaaaaaag aaaaactgcc aatcgacttt agaaaatccc
    57121 caacactgca agagatcctt gcatgttatc cagatggact agatgatgta tttcttttgc
    57181 atcatcctag gctttccaaa acttccttac aattattcga gaagcattct ggtcgccaaa
    57241 tgactatagc aacttctaat aaaagtatgg tattattttc tacgactgga ttcgaagctg
    57301 atttctctgt caatggaaaa cagatgcatt caaactacgg attagcaatc gaaccgcaag
    57361 aaatccctga tatcgttcat ttccccaaat ttggatcgat caacctccat cctggtcaag
    57421 aacggatcag tcagacgatt tatcggttct ctgcacaata acaagagaaa ggtgttttta
    57481 tcatggctat taccgtaaaa gatgtggcga aaaaagccgg tgttgccacc tcgaccgtct
    57541 ctcgtgtcat caacgatcat cctagtattt ccgagacaac aaagaagaaa gtccgaaaaa
    57601 ttatggatga actaggttat gttcctaaca tgactgcccg caatctagga aaacgcattt
    57661 ccagtgccat cggcgtaatc ttaccccctc ttgattcaaa agagcggatc ggtaacccat
    57721 tttatcttga gatcatggaa gcaatcaacg aagaagcgcg gaattatgat atgactacag
    57781 caatcgctac tgctaaaaat tttgaattgc tgttagagaa cgtccagcgt atgcatttac
    57841 aaaaacaagt agatggtttt attctagtgt attcagatag tcaagatact gtcattgatt
    57901 atttatacca aaaccacatc cctttcactt tgatcggaca gccttatcat catgagaacg
    57961 aaatcgttta tgtagataat gataaccagc ttctaggtaa acaagcaaca gaatttttga
    58021 tccagaatgg acataagaat atcctgtttg tgacaaacac gactcatgaa agtttgtatt
    58081 tcgaacgata tttcggttat caaaaagcaa tgatgatggc tggtcttcct gcgttatcca
    58141 gtgtagtact agagcatccg gaggattatc tgtcctttga gaaaacgttg aaagaaaacg
    58201 aagccacagc attggtggtc attgacgata tcttcgccct tcgcacgatg cagttggcgc
    58261 aaatgtatgg ctatgtcatt ccagagacac tctccgtcat tagcttcaac aactcgatct
    58321 tctcaacatt aacacaccct taccttacaa gtatcgatat cgatatctcc gaattaggac
    58381 gtgtcgctat gcaaaagctg cgcgaattga tccatgaaga attgagcagt ggcgtacgtt
    58441 tggtcatccc tcatcgcttg atcaaaagag agacagtcgt tcctttagaa aacccatact
    58501 aaatagctga ctcactaaat acgctgacca tttatcctat ggtcagcttt ttatgtaaaa
    58561 gaagatacta cttctaacac attgtttatc tgtaaaaaag agcgtgggac aaaagtaaag
    58621 aacacttttg tctcacgctc taaacacgta taaacggcgg aagcagaagc aactccttcg
    58681 gaaataagct gaaattcaca aaaatttaaa aagcaatttt cttgagtttc ttcttatttc
    58741 ttggagttaa acgcttctgt cccagcctct tttttccttc cttcaatttt ttacacgtcg
    58801 acgattcaat aaaaaaccgc ctaatattgt aaagacaggt gcaagaatcg agaaaaaggc
    58861 gaatggcaag taatgcaacg cgctaacttt catcgttccc ataatgaatg tgccgctgac
    58921 tccccacggt acgagagaat tgacggtcgc acctgaatcc gctagtgttc gtgtcaaata
    58981 ggtttttgat aagccaacgt catcaaaaga acgcttgaat gtttctcctg gaagaatgat
    59041 ggacagatac tgttctccaa cgatcagatt gattccgata cagctcaagg cagtaaaccc
    59101 gactaaacga gaaggtcggt ccatcttttc ttttaattct tgaacgatgg tatcaacgat
    59161 cagatatttg atcagtaacc cacctaatgc caatgcaagt aaaatcaaac tagcagaacc
    59221 taacatactc atgatcccgc ctcgagaaag cagttcatct agctttggat caggtgtatt
    59281 tgcgacataa ccattcatca agatgtctgc tgcttttccg accgtcaaac ttttctcatg
    59341 gataaaagaa agaacgagag cagctgtcga tcccgctagt aatgtaggga tagccggaat
    59401 ttttttgatt gcccccccca aataaaataa ctagtggaat caatgtccaa ggagagatcc
    59461 aaaagctcgc tttcatgttt tggatcattt cattgatact agctagatcg gctgaatgac
    59521 tgttatgtcc taatatcgta taaaaaatca acgaaaggac gaatgctggg aaatccgtat
    59581 aacgcatacc agcgatatgt tcgaatagat taactcctcc aatacccgct gccaagttgg
    59641 tcgtatctga taaaggcgag cagttattcc ctaaaaaggc accggaaacg actgcgcctg
    59701 tagtcattgc atcattgaat ccaagtaaat gaccgatccc caaaaaagca attccaatcg
    59761 tcgaaatcgt tgtaaatgaa ctgccgacag tcactccgac aattgcacaa acaagaaatg
    59821 ctgtcggtaa aaagaaacgc acagaaacaa gtttaaatcc ataaaccata atcgtaggga
    59881 tggttccaga taaaatccat gaagcaacta agacaccaat caaaagaaaa atcaggattg
    59941 gaatgatccc tggagtgatt cctttgatga tcccgtcatg gatctcatcc catgtgaact
    60001 ttttaaatct gccataaaac aacaaacaca tgaaagctgc aaggatcggg atatgtggcg
    60061 agagctggaa tccgatgatc agtactccta ggagtgccaa caacacgatc aatacagcga
    60121 tactttcttt taaagaaata tttttattca tcgtcgatct cctatttcaa atgaaaaggc
    60181 cctgccatga aaaaactatt cacttggcag gacctcctac taaatcagcg acaaaacgtc
    60241 ggctgaaaga cttatttttt tatttttctt ctaaactttt ttctacctca atcccccaag
    60301 aatctttctt gaagtgattg atgatcaatg gaataacgaa catgaccact gtgatagctg
    60361 ctactaataa tgcatcactc aatgtcgctg tacctaatgt agcaaatacg acaacgatga
    60421 tagagaagat cagcatgcag ctgactaccc aagctaatcc gtttccgttt ttaccaattc
    60481 ggtaaggacg ttcgaattct ggatgtttct tacgcatttt aagcaatgaa acagcaatca
    60541 aaatgtacac gatacaataa ataacagttg tagcatttgt aagtgtcaag aatacagcac
    60601 ttacgtcatc cattacacca taaagcaaag caaataatga aataacgatt gattgtgtta
    60661 gaacgacatt tctagatacg ccgtatttgt tttctttatg gaatccgaat tttggtggaa
    60721 ggaatccttc acgagctact tggatgattg tttttgatgg tccagtaacc caagctgata
    60781 attgtaaaag cacaccaata aataccatga agctgaagat atttccgatc acttctggta
    60841 agcctaggat ttgacagtca atcaagatag gctgcgtgat atttgctaat tccatttttc
    60901 catctggtac gacatttgct acaagcatcg cattgatgac attcaataaa actaatccga
    60961 tcaaagcgat aaatacgcct tttgtataat tttttgttgc gtctttcaaa cgaggcatgt
    61021 aaacagaact catttcgatc ccaacaaaaa taaatgtgat accagctaag tatttcaatg
    61081 aatcaatatg ttccaagtca gggaaagctt ttgaccatga aaagtcacct agatagccgt
    61141 ttgagactag tccgactttg aaggctgcca aaacacctaa aacgaacatg atgactactg
    61201 ggatatatac ccctagccat acaccgatgt tcccgccgac ttttgccata tcgaatttca
    61261 agttcaagat cgtgatgatc cagtagataa ctaaaataca acctaaaacg aaccagtgat
    61321 tattgccaag ttctacatta ccaaatgtgt ttcctaacaa tggtcctaaa gtagaagcga
    61381 ccattaccat acctgggaac atttgcaccc ataatagcca tgcaacgaca aatccccatt
    61441 tgctgcccag tgctgttttt acccataact gaggaccgcc ttcttgagga agcatcgtgg
    61501 aaagctcacc ggaaaccatt gatatcggac cggcaaaaaa caaaactgca aaaattgaat
    61561 aaaaaatcaa tgtccaaccg actgcggcta acgtaggaat actccgaacc gttgcacaca
    61621 gtgccattgt cagaccgata aaggtcccaa gacccatttt acttacttca gatttactca
    61681 ccgttgacac tctccttgat tttttggata aaataacggt gtctttgaag tagtttcagc
    61741 aataaacgaa acaattcagc gaatatttga ggggattctt tgagtttatt gcttgaaggg
    61801 tttcttcaaa gacaacctca aaacaaaggg atcgaagagc ttaggtctcc ccttgctctt
    61861 cagatccaaa catgcgtcag aaacagttag tattcaagct gttttctaac atgattacct
    61921 tgcttatttt gcttcgcttg ccaataattg gtctgcgtag attttttcca atttttcttg
    61981 aagagctgct ttgatttttt cagcatattc ttcaaagtgt tcttctttgt tcatgtatgg
    62041 tgtcattacg ctggcacgca atacagttac ttttccggca cggttccatt cttcatctga
    62101 gaatcctagt tggttcacaa attgtaatgg gctgttgcca tagtctggga tagcaaagtc
    62161 agtatgtgaa gttaagaact cattaccgta aatgcttcct ttcacgtatg aagaataatc
    62221 atatacgtca tggttcaatt tattcattgc aactaagtca tcgttgcctt tttctttgaa
    62281 tacatagtct accatattga aatctggata agttaatgga tgaacttcga tttctttgtc
    62341 tcctacttta aatgacaagt cattcaagaa gttgtagaaa cgatgtgcac cttcgattga
    62401 tgcacccatt aatttaccat atcctgtgac attcaaaggt aagacatggt gtgctgccca
    62461 aacgctggct gctgttgccc ctgcttttga accttccaag atataagccc caagtaatgc
    62521 tgggatatct gcgccttttt caaatacata tgtcgcaaag taagagataa cgtctctcat
    62581 gcggatatct ttgatgacga taccaccggc agaatatgga acatagccca ttttatgtgg
    62641 gtcaatcgtt acagattctg cttcttcgat tgctttatat gcactgtgta cttcttctaa
    62701 gatataatct ttgttttctg taaagacatt gtatttgtaa tgaacatctt ttaaatcttc
    62761 aaatggaatg aagttgttgt cttcgtctaa gaaaatcgca cggccgtatc cgccataagc
    62821 agcatctacg tgtaagtaga agtaaatacc gtctttttct aatacgcgac gcaatgcaac
    62881 gattttatcg ataccgtcga ttgctccttc ttctgttgat cctacaacac cgactacacc
    62941 taggattggt gttttttcag ctgctagacc acgaacgatt ttttcaagtt cgttgatgtc
    63001 catgcgatag ttgtggtcaa ctggcactgg aatcacttgg tctaaaccga taccgatgat
    63061 gtcggcagct tttagccatg aatagtgttt agtttgtgga accaaccatt ttcctaattt
    63121 ttctaaatgt tttccgctac gtgctgagtg agctttgatt tcgtcgattt tttctgggac
    63181 gctgtctaac agattcatga tttcttctgt tgacaagttc attaattccc aatcgctttt
    63241 tccagcaact agttcaggtg tcacttcttt cattgcaagc ggcaatgatt tgatgttgcg
    63301 ggcataccaa agtccttcta agtttgctaa agaaccatca gcaacgatgt ggccccagcc
    63361 atctttatag ctcattaatt ttgcaaattc cattcctact tcttcttcca tttggcttgt
    63421 tgcaggagaa gattcatagg caacgttatt accattccat agcatagcaa aattgtacgc
    63481 tagtaaagat ggcatcaatg tttcagagtt catatgaccc cagtaacgtc cggcattatg
    63541 ccaaggaacg gaatgggtac gcatccgcgc tgaaatttct gatagaacat cctttgtttt
    63601 attcacagtg tgttcaaaac tagcactgct tttttcttct ggcgtaataa taggcatgtc
    63661 ttgaggcatg tagttttgac gccagcctaa atgttcatcc accaattcat tcaacaaagc
    63721 tttatagatt tggccgttct cagctttgtc cccaatgaat agggcattta ggtttagatc
    63781 tttcgacaat gattcactca tagtgaaacc ctcctaaaaa aatatttaaa ttttgtcgag
    63841 ccctacatta cacctgttct tctattctgt aaactaagtt ttggcctgat ttttaatcat
    63901 attttaatat gtatcaatta tccgaattgt tcacactttt gaaataatta aaaaaaacga
    63961 gggaatttac aaatgtaaac tccctcgcaa agattgtatt aacgacaacc agcgttctat
    64021 tttaggatgg gtttcaaaat tggaatgttg taatagtatt tccctttttc aaggtaaaaa
    64081 cttactaaat tctaatcaat tactttggcc aaaaagtaat ttttcttacc ttttcgaata
    64141 accacaaact taccatcgaa ttcatcggat ggatttatga caaaatttaa atcggtaacg
    64201 cggtcaccgt taatacttat agctccgttt gaaacatctt cacgtgcttg acgtttagat
    64261 ggttcaattt ttgtggaaac aagcagttcc acgatatttt caggtgtgct tgaaatttca
    64321 acgttcggca ttttaccgaa tccttgcgcg atttcttccg catttagttc tttaatattt
    64381 ccagagaaca atgcttgcgt tattttttgc gcttctttca agtcttcttc actatgcaca
    64441 aatcttgtaa cttcttctgc caaacggcgt tgtgcttcac gtttctcagg ttctgtctct
    64501 acttttttcg ctaagtcttc gatttcttct tgagacaaga aagtaaagaa tttcaagtat
    64561 ttcactacat cgcgatcatc ttgattcaac cagaattggt agaactcaaa tggtgaagtt
    64621 ttcttcggat caagccaaac ggcaccgcct gcagtttttc cgaatttcgt tccgtcagcc
    64681 ttcagcatca atgggatcgt taaaccgaac gcttctgctt ctggtccttc taattttcgg
    64741 attaggtcta atccagctgt gatatttccc cattggtctg ctccaccgat ttgcaattgc
    64801 acatcgtatg ttttatgcag atgcaaaaag tcgatagatt gcaggatttg gtaagtaaac
    64861 tctgtaaatg agattcctac ttccaaacgg ctggcaacga tatcttttgc taacatcgtg
    64921 ttgatgttga agtttttacc gtagtctctc aaaaattcaa gtaaagagat ttttgacaac
    64981 cagtcgtagt tgttcacaaa tgtgatattt gcatctttac caaacaattt tctcatttga
    65041 ttggaaagtg cgtccacgtt atgttgcact tgttccatcg tttgcaacac acgttctgtt
    65101 ttgcggccgc ttgggtcgcc gatcgttcct gttccgccgc caatcagaat atatggatga
    65161 tggcctgcca attggaatct tttcatcatc ataaatggaa tcaaatgtcc gatatgcatc
    65221 gaatcaccag ttggatcaac gccgcaataa agtgaaatgc tcttttcttc aacgagctcg
    65281 cgaagtcttt cttcgtttgt ttgctgatta atggcgtcgc gccaagttaa ttcatcaata
    65341 atattcattt tactgacctc cgtgtagttt ttttatgaaa gcaggaacct gctagcatgt
    65401 gtaattaatt atttcttcag gataggatag gaaataaaaa aagtcccttg gcatataagc
    65461 caagggacga aatctcgcgg taccacccaa tttgtatgtc tagatatcca acatacctct
    65521 cgaacattta acgctgtcgc gtggcaatca ctgccaaaga ctcctgaaat gtaattcgct
    65581 ttaaagcatg tactggtttg cagcgaccac cagctttctg aaacattggc tttaacaact
    65641 acttcgtttc gatcttcgtc ttgttattat taatatgtgt ctatcataga gcgcaacttt
    65701 ttctttgtca acagaaaaag gatatttttt ttaaattcct cattttttct tttttgaatc
    65761 cgctctaatt ccgaacattt tattttcaat tattgttaaa agaaataact ttttctgtat
    65821 tttttctgca atttatcgag aagtcacttt actttgcctc ttattctttc ttcgttacaa
    65881 taaggaatgg gacaagtaaa aaaatgaaaa agcaagggac gaggtatatg gaaaaaaagc
    65941 aaaaaattat tttaggagcc acttctgctt taactatcgt tattttaatt ctaagtttgt
    66001 tttttgtcat ccgatcatct acaaaaaaag aaccaatcat tcctgaaaaa aaaataacag
    66061 aaaaagcaaa agaaccgaca gatgataagc aacaactagt tactcaagca aaaaatctgg
    66121 ctcaaagcta cgattatgac caagcgattg cgttattgga aaaagatagt aagaacggat
    66181 ctactgaaac acaacagctt cttcaaacac taaaaaagga gaaagaacaa ctgatcgact
    66241 ggtctgatcc tactcagatc tctcatgtct ttttccacag cttgatcgtg gacccgcaaa
    66301 aagccttcca ctctcaacag gcacaaggat acaaagatta tatggtgact gttgaagaat
    66361 tcaaccgttc gatcgaacaa ctttatcaaa atgattttgt tttagttaat ttgaatgatt
    66421 tgatccaaaa agacgaacaa ggaaatcttt cctttaacgg gcttgcgcta cctgaaggaa
    66481 aaaaaccatt ggttctttca caagatgatg tcagctatta tgaatatatg gataattccg
    66541 gttttcctag ccgattggtc gtatcaaata acaatgaaat caaaaatgtc tataaagaga
    66601 aagataaaga agaaatcggt gactttgaca tggttcctct gatcgatgcc tttgtcaaga
    66661 aacatcctga tttttcttat cgaggcgcaa aaggtacctt ggccctgaca ggttacaacg
    66721 gagttttagg ttatcgaaca tcaaaatctc aatatggaga caatgaaaaa acaaaaaaag
    66781 agattaaaga agctaaaaaa gtggcggaac agttgaagaa agacggctgg agctttgctt
    66841 cccatacatg gggtcacttg aatatgactc aagcttcact agaagatgta aaaaaagaca
    66901 atgaattgtg gcagcaagaa gttgcaccta tcctaggaaa aacaaatatt ctgatttatc
    66961 catttggtgc agacatcagc gactggcagc cttattcagc agaaaatcaa aaatttgctt
    67021 acttgaagag tcaaggtttc gatattttct gtaatgtcga tgcttctaca ccagcttggg
    67081 gacaattagg tacggatttc tatcgaaatg ctcggatcaa tatcgatggc attcgttttc
    67141 aatctgattt agacggaaaa aatcctattc ttgatccatt catcaatgtc catgatgtct
    67201 atgacaaaga agcacgcgaa tctgcttgat tttacgtcat ttatgaacca aaaaagccga
    67261 actgacattt tatcgtcagt ttcggctttt ttatgcttta tttcttcttc ggtgcgattc
    67321 ccttgatcag gacttctgtc cattctgctg tatatggaag cagttttgcg tatatctccg
    67381 gcttagaaat tccttctacc attgcttgaa aatagaggat caagaactca tccgaatatt
    67441 tcaaatccac ttttccttct ttccgccctc gatggaaaag atcaagcatg atactgaaac
    67501 tttcttgcgt atacgcatcc atcgcgtcag aaaattcttt tttttctttt tttgtatagt
    67561 atgtcatcaa atcgatataa aattgtttgt tcactcgatt gagataacgg attttgtttt
    67621 cactcatggc aatcagtgtt tcttcaaatg gaagattttc cgcaatcaac gctttcgctt
    67681 cttgccctaa atcattcata aatgcaaaaa atacttcata aatcagccct tccttgctgc
    67741 caaaatattt aaaaatcgtc gctttactta cctgagcgtt ctcagctacc ttatccattg
    67801 tcactccagc ggttcctatg tctgtgttca tcaagtcaaa agctgcttgt aaaatctctt
    67861 tctttttctc ttgtgctctc ttttcaaaac cgttcatttg tagagcctcc cgtaatttta
    67921 aacttttata atatatatag ttcaaattta ttctgaggtt tattataact atctattgag
    67981 aaagtatcaa gctagcaatt ccttgtttat gaattcattg acagaaattt ataaaaagaa
    68041 tattatgtac taaaataata aaaaaagttt tataaaaagg tataaaacct ttttattaaa
    68101 ctatttaatc ttgtttagta tatattttta gaaaaaggag tggggttttt atggcagaaa
    68161 tcgtcaaagt cacacatttg aaaaagagct ttggtcgttt cgaagcttta aaagatgtct
    68221 ctttcaccgt acattcaggt gaagtcgttg gatttatcgg accaaatggt tctggaaaat
    68281 ccacgacgat tcggacactt ttagggatta taaaaaaaga cggcggaacg gcaacgattt
    68341 ttgggcaaga tgtatgggaa gatagtttat ctatccatga acgtctttct tatgttccag
    68401 gcgatatctc tttgtgggga aatttgactg gaggagcgat catcgatctc ttcatgaagc
    68461 ttcatggaaa agggagtgct caaaaaaaag atgaactgat tcaacgtttc tctcttgatc
    68521 ctaagaaaaa agcaaaaaac tattcaaaag gaaatcgcca aaaagtgggc ttgattgctg
    68581 ctttggctgt tgattcggat ctctatttat ttgatgagcc tacttctggt ttagatcctt
    68641 tgatggaaac gattttccaa gaagaagttg aaaaattgaa agaacagggc aaatccatcc
    68701 tactttcttc tcatattctc agtgaagtcg agcgactagc ggataaagtt gtgatcatac
    68761 gcgaaggaac actcgatgaa gaaggaacac tcgatgaatt gcgtcatttg actcgttcga
    68821 ccatcactat agaaacagaa gcagagaata gtcacttagc acaattgaac ggtgtccatg
    68881 actttgtgca aaaaggtcac ctcgctcaat ttgctgctga taacgaagct ttcgatgtga
    68941 ttttagctga agcgtccaaa ttaggtgtga aaaaatttga atctattcca ccgactcttg
    69001 aggatttatt catgagacat tatgaaggat gaggaggaag cgaaatgact gataaatttt
    69061 cacgctggtc cacccttttt tctcaaaacc ttagccgtga ctggaaaaag atcctgatat
    69121 ggctagtcgg tgtcactgct ttttctggtg gttttgtccc tgcgtttgaa gaattgactt
    69181 ccggacaagg attagctgga ttatacgaaa ccttgcaaaa cccggcaatg attgcaatgg
    69241 tcggaccaac tccagcttcg aatgctgctg agtatacttt aggagcgatg tatgcaaatg
    69301 aaatgttgct tttttgcagt ttgtttgctg ctgtgatctc tgttttacac gtggtgagcc
    69361 aaacgagaaa aaaagaagaa cttggtctga ttgaacttat tcgttccttt cgagtcggac
    69421 gtcaagcaaa ctctttagct gtcatcgctg aaagtattct gatcaatttg cttttagcaa
    69481 tatcgatcag ttgtacgatg atttttttcc aagcggattc gatcactgca gaaggtgctt
    69541 ggctttttgg gctatctgta ggtagtatgg ggattttggg gagtgccgtt gcactgtttg
    69601 ctgcacaact gatgccaagt tcagccagtt cgaatggtct gtctttagcg tttttaggtg
    69661 gactttacct tctacgagca ataacagatg tagctgattc ctccctttcg atgtggaatc
    69721 ctttaggctg gtcttatttg acctatccat ttacaactaa caactggatt cctttgcttt
    69781 atttgttttt gttcagtcta atcttgataa tcagttcatt tgttttagag gaacatcgag
    69841 atttgaacac cggctatatc cccgaacgtg aaggaaaacc gtatgctaaa cgttctcttt
    69901 tatccttgcg tggtttatta ttctatctaa ataaagggat gacaatcagt tggcttatca
    69961 cttttggttt gatgggggcg gcatacggct ctatctacgg gaatatgcaa cagtttttag
    70021 aaagtaacga cttaatgaaa cagatgttta tccaatctgg cgtctcaatt gaaaaaaact
    70081 ttacaagcac gatcatggtc gtcttgattt gtctagctgc tattttacca attgctagca
    70141 tcaatcgttt atttacagaa gaaacccacg gacgtatgaa tcagctgttc gcaacaaaaa
    70201 tttctaggaa ccaactttat tggaccaata tgttactagc tattctattt gctatattgg
    70261 caatcctgat tagttctggt gcactagggc tttctgcttt ggcttcgatg aaggatgcga
    70321 aagacatgga tctattgatg tttcttaaag ccgggttcaa tttcctgcct gccgttttag
    70381 tgtttatcgg aattagtggc tttctattcg gatggcttcc tcgaatcggt aaacttgctt
    70441 atatctactt agcttactcc tttgcactca attactttgg cggaattttg gatttaccag
    70501 aatggttttc caaaacagct gtccctagct gggttccacg gatgccaaac gattcttttg
    70561 atctttccgt gttccttacg ttatcatgta tcagccttgc actgttcgtc cttggttcta
    70621 ttggttatag gcgaagagac ttactagaag gataataaaa aagcatgtac aatttcatgc
    70681 tagcctccaa atctgggtca aaaatccaac atttggaggt cattttttta tttacaagtc
    70741 ttctaactgc tctttatcaa tgatccagac ttctcgattc tttcttttta cataaccatt
    70801 ctcctctaat aatttaaatt ttctagataa agtttcgggg gtcgtaccga taaatgcagc
    70861 aagttctttc attttcattg gcaggaaaaa gtgatccttc cctgtcgctt tagctaagtc
    70921 aagcagatag acagcgactc gttcttctac tttttccatc atcaaaaaag ttgtctgctg
    70981 ctgtactttt gttaatttct caacgttgat tgctaaaagt ttcagactaa gggcgggata
    71041 atgcagtaag agttccgaga aatctttttg tctcaatatg caaatttccg ttttttctag
    71101 tgcttcgcca aataaagact catttggaac gcctagcaac tggctctctc cctcatatcc
    71161 gcccggctct attactcgta aaagctgttc ctttccgcta gcagataatt gatacacttt
    71221 catactgccg gaggccacga tcactaattg aggttctcca ttcggcgcaa gaatctgttc
    71281 tcctttttcc acatagtgat gtttgacaag tgcgtgtact ttttcttgat cttgctgtac
    71341 taagtgattg aacaaaggaa caaatgaaac acataaatga tcatgactca taatctctcc
    71401 tccttctaaa cagctatttc taataaagaa acataacttc ccttattcca actgataatt
    71461 ttcttttatc atagcataaa cgtcaagcga accagatacc agcaaataga gtggatttct
    71521 ttttgtccct tgctttattt tccttctttt gagaccttaa gtaattgatt cctatcaatt
    71581 ttttaaatat ttactttttg aataatcaaa aacaaacctt cactcgcaag ccgagagtaa
    71641 ggtttgtttt tcgcattgct tatttcgtgt tgtctattga aatttttccg cacctagctt
    71701 ttgatatagt ggtgctagtt cttgtaaggt ttcagcggtt atttgctcaa cgtgttcgat
    71761 ttcttgcgga tagaagaata gtttacccat ttgaaaggtt cggtctctca tcgctttttt
    71821 caactcttct tgtttctttg tatcggacaa atagtcagac aaagctaagt ggtcgtcaag
    71881 ttcatgttct ggttgcggcc atatgtaata atccttgata tcgactgttt tgctccactc
    71941 tttcagtatc gcaagcaact ggttatacgc tgcaatgcta ccatatcgtt cttcgctttt
    72001 ataatgttgg tacatcaaat agatttggta ttgtttttga ttcaacaaaa ctgctagaca
    72061 ggcattctcg tcttgacgag attcgcttcg gtacgcgctc caaaaatgac tgcgtaaatt
    72121 ccagccattc gtccagcttt cgattttagg tttgctcatg ccgtacatat caggcaaaag
    72181 tgcagctgtc tggagctgaa tctctttcca tttttgccag tgttctttat attctttctt
    72241 gatttgttca atcttatctg ttggatggct ctctttgagc tgtttgaatg cgtagattgg
    72301 tcgatcaaac aactgataat ctgattttcc aagttccatt gtttcgcctc tttccgttat
    72361 cttttgtatt ctacctgaat tttgcgatat ggacaaatag aggttgtgaa aaagctgttc
    72421 tgcatcaagt cataagaaca gccaaacaaa aaactgcgat gagcatcacc gcagttttat
    72481 tgaacttaag gttgattgat cacatctaaa agcgttgaaa ataaaatggc actagaagca
    72541 gctcctgggt cgatatgtcc gattgcacgc tctcctagat aggaagctcg tcctttttta
    72601 gctaccaaga ctttggtgtg ttcttttgcc tggtcaatga tttcttttgt taaattccct
    72661 gccttcaatg cctctgtgac tggcagccaa acatctaaca tcgttttatc gtcagcttct
    72721 gcctttcctc ggctttgaat acccgctgtt ccctgctcga tcacttcgcc taatttttct
    72781 tgagaatcaa tagaatcgac ctcttttgtc gctttcatca tgttcatgaa tgcagatccg
    72841 tataacggac cagaagcccc accgactttc gatatcatcg ccatagagaa tactttgaat
    72901 gtatcgctga ttgtttcagg atgatcggct tgaaaagctt cttcataagc tgaaacccct
    72961 cttcccatgt tatttccatg gtctccatcg ccaatcgggg tatctagatc actgagatat
    73021 tgtttgttct gattgattgc ctctgcaaat tgcgtgagcc attcttggat ttcttgaacg
    73081 gttagtttca tattatcacc cttttatctt gagatttttt accatgaaat cgtctgtaca
    73141 ttgctttcta aagaatcttt ccattgtgtc tccgtcaagt cgatcagtgt tagagaaaga
    73201 ccttgcatat ctagtgaggt cataaaatta ccgacttttc ggaaaactac attgacgcct
    73261 ctttcttcca acagagctaa aacatcattc atgaacacga actgttccat caaaggcgtc
    73321 ccgcccattc cgttgactag tacacctgct tcttttggta aattcgagta atcatctaaa
    73381 atcttagtaa caagttcctt tgccagtact ttagaaggct gcatcttttc tcgacgatag
    73441 cctggctcac cgtggatacc aacaccatac tcgatctcat cttctcctag ttcgaatcct
    73501 ggtttcccta cttctggtac agttgctgct cgaagcgcta gaccgatcgt cttagttgcc
    73561 tgtacgacct tttctcccag ttctttcaac tcagctaggg aagcaccgtt tcttgctgca
    73621 tcgcccacga ttttgtgtac aaggacagta cctgcaactc cgcgttttcc agcagtatac
    73681 gtactatttt caacggcgat atcatcatct acgatcacac tttctacttc aatatcgtcc
    73741 atagcagcta attcctttgc catatcgaag ttcaatgcat cccctgtata attcttaacg
    73801 atcagcaaaa ctccttttcc actatcggct tccttaatag ccgtctgaat ctgatctgga
    73861 gttggagaag taaacacatc accaagcacc gctgcactta acatcccttc ccctacaaac
    73921 ccggcatggg atggttcatg tccgcttcct ccaccagaaa ccaaaccaac ttgttccgct
    73981 ttctgattct tggctacaac acgggaagat tctacacgat gaacaagttc tggatagctt
    74041 tttactaatc cttccagcat ttcttcgaca atattgcttg gatcattcat gatttttttc
    74101 aatttattcc catcctttct ttccggcatt ttgtgcttct gttaagattt gctgagtatc
    74161 atctgttata ccggcagtga tggctgctgc aaaagctcct tccactaaag gcgcatccac
    74221 cagatgataa cgttgctgct gctcttcttc caacatgtct tttgccagtt ccgagttcaa
    74281 taccgcgcta ccgatatccg caaaaacaaa ataactagct gcatcgcttg attcattgac
    74341 tgcttctacg attttcatcg ggtctgatcc gatctcgcca tttattccgc cgagagaaaa
    74401 aatttgcacc tcttcggatt tttgcatctg ctcaatcatt tctttaatac catctgttac
    74461 tttttgacta tgagaaataa gcaaaatact ttttttcaca agaatcttcc tttcttttac
    74521 atagttgcta acgattggtt tcgctttcat taatgaacaa ttcaagtata taataaattt
    74581 ctaattttgg gaaaatatgt gtagtgcttc ttgaagtttg ttatacttta attaaaagag
    74641 aggagtgatc gaatgattac aacaacaacg aacagtgtag agggaaaagc cgtagtagct
    74701 tataaaggga tcgtttttgg tgaggtcatt actgggatcc atgcatttaa agacttggag
    74761 gcggggttgc gaaatatctt tggcggccgc tcaaaaagct atgaaaacga actaatgggt
    74821 gcaagagaag aagcacttgc cgaaatggcc gaacgtgcaa aagcattagg agctgatgcg
    74881 atcattggcg taaaaatgga ctatgaagta ttaggcagcg acaatggcat gctgatggtc
    74941 acatgtagtg gaacagctgt ctccacgaga taagtagggg acatctgttt taataactaa
    75001 agagagatgg gacatgtagt ggcactcaag aattagattt ttcagtctaa cttcgaggta
    75061 ctctaccttc ccatcctctc ttttttattt ctttttgcgg atgattccgt aagctgctgc
    75121 gactaacaca cccgcccctg ctaaggaata actgacagaa gctgtttttt catttgtttt
    75181 tggcaaagtc tgacttgttg atttggatgg ctctgtcgtt tgctgaactg tttctgtcgt
    75241 gcttccagag gtcactgatt tttctcctgc cgaatgcaaa atatctttta ttcgttggaa
    75301 actagctgct aagtcagctt tttttgcttc aaaatcatta gcaactgttt gtgcttcgct
    75361 gatctttccg tggattgctt gactggccgc tgtgatatcc gcttgagttt gacttagctt
    75421 tccagaagct gtttgagcaa cctgatttaa ttgctgattg aattcttttg cttgttggat
    75481 cttcccgtca agatctgttt ggacagcttc cgcttttgct ttcgcttcgg caagcttttt
    75541 ctcaagttgt gcacggtcat ttcccacttt atttttaaga tcagctaaat cttgatcgat
    75601 tgctgcttgg tcttctttca atttgttttt tgcagcttct aatgcttctt cgagttcttt
    75661 tcttttattt tccaagtctt gcaaatgatc gatttggtca gaagaggtag aactatttat
    75721 tgatgtatct tctgaagatg aaatcgtttc tcctgaatta tctgtcggta cattggaagt
    75781 catttctgtt tccgaggcac cgttttcagc accagaagag cttatggttg ttgaaggttc
    75841 tgtttgagca ggttcagaag tttccgcaaa agctgtctgt cccaataaga aaatactgga
    75901 aacagcaatt ggccagatta acggcttcat tctttttttc atcacttttc ccatccttac
    75961 tactttttaa ctaatttctt attataagca aaaatgtttg gaagaaccat aaacacaaca
    76021 ggctgtttgt ctaaaaaacg gtgcatcttt tatttttttg tacgttccgg gcttttccat
    76081 gtcccgcttc cataacctaa aatcgttttg actgctggaa tgaaagtcgt cacgatcgtt
    76141 atcgcgttca ctatccagaa caaaagcata tatagtggtg cgaaaagaag gtatttcaat
    76201 tttcttcgtc gatcatctac aatcagcgaa gctagcaact ggaaaaatcc tgcgaccatt
    76261 tcaaagcaga tgaacacaaa actgaatgta aaagtaatat aaatctgttc gtagtttcct
    76321 tgatatacat aatgcccgat taatccagca aaaagaacta cggaaataca aaagaatatt
    76381 gaccagacaa tactcaatgt ttgatcaatg aagatgatcg ttcttccaat atgtttaaaa
    76441 ggatggagca tcactttttt gaaattcgtc agccagactt ctgttccacc ttttgcccaa
    76501 cgttttctgt gtcgatatag catcttcaac gtcacaggta cttccatgaa aaagataatc
    76561 tcaggagcaa aaacagataa ccagtcattt aactgatgat cccaagcaat actgatgtct
    76621 tctgtcgctc gatcttgtct gaatccgccc acatcgatca aggcttcttt tcgatacatc
    76681 gtatttgctc cactgtacgc ataaagacca ccgaaaacag ctgactgtgt tcgtttaatg
    76741 atgcccacga tacttgagaa ttcaaccgtt tgagattttg caatcaattt ggtacgattt
    76801 tggacatcca tatttgcagt gaccgcagca atatgtcttg caccagggcg aatgaaataa
    76861 ttcacatacc taatcagtgc atctggctcc ggtaccgtgt ctgcatcatt gcttaaaatc
    76921 aatttccctt ttgcaaaggc aagtccgata ttaaacgcgt gggcttttcc tttatttttt
    76981 tcgatccgaa ccacacgaag attagcgtat tttttcatca gtctagctaa tatttctggt
    77041 gtttggtccg ttgaaccatc gtctgtcact aatacctcat agttgtgata attcaatttc
    77101 gtcatcaaat actcgattgt atattcgatc acaatttctt cattatgggc tggcaccatg
    77161 atcgtgatga acggttcgac actcaaggga acatctaccc attctttttg cttatgtttg
    77221 tataaaaaca cataacacca gacaccaata aaccatacaa atccgcctaa aatcggataa
    77281 gaaacgagaa aaaaatacat aatagacaaa caagtatcta agaataaatt acctgtatgg
    77341 gtgattgaga tcatttcagt tccaccccat tttctttata caaatctgca atgaatgtcg
    77401 tatctagatt tttctcttcg gagacagaat aaaaacggac cgtttctctc tcttcttttg
    77461 ttccaaaacg ttccgtatac acttcttcaa gtaattcttg tctttttttc aatttttcat
    77521 cttcatattc aaaagattta tttacttttt tgtatagatt tcgattgttc cacctagtca
    77581 atacaaatga ggtaatcagg aaactgaaaa aaatcaatac aaaaaagccg attaagaaat
    77641 acagcatttt cttttctgat aaaaaagcgt acaaggaaaa atccttggct ctttctggtc
    77701 tcgttaatgg gaaaaagacc catataaaag gaagaacaac gatcatccat cctaaaagag
    77761 ccactaacgt ttgccaaatc tttaaccagt aattaccttt tgaaaaatac ttatctttca
    77821 ccaaaattga tgcaacttct tctcttgtta cttttttcat atcctcacct cacgtttttt
    77881 tgttacgacg taggagttta ccatacattt catttctttt cacataaagt gttcctaaat
    77941 ttttcctaag aaaaagaaca aaacatttct catcagcaaa tgaaaaatat tttgttcttt
    78001 ttatcagttg ttctttttat tttttatctc ttaattatgt tgctctttcc aatacgacaa
    78061 tgcttttcat tcctctagat atcgccgtgt acatttgtct gcgtcttctt tgctcatctc
    78121 catcgttttc aaatggatat aagattacat gatcaaattc cagtcctttt gctagactca
    78181 aaggaatgat ttggcagttt tctaatccat atgaattttt tttaatcgat tcttgtagcg
    78241 tttgggtttc ctcttctgtt tgggtgataa ctgccgcttt ttctcctttt agagaaacca
    78301 aaatctcagc tagtattttc aacaattctt cagaggatcg aaaagagcgg tattcgggtt
    78361 cttttccttg cggtcggatc gatacgatgt cgatcttctc ttgatccaca gcataggttt
    78421 tgaaaagctc tgtgattgct ccgctagaac ggtaactatt tctaagatca taccgatgga
    78481 tcggcagatg gtagtcgtcg aaacaacgca taatatcagc aaaagtagtg gaagaattaa
    78541 agattgcctg attctcgtca cctactaaag taaagtgagt ttttggaaat aattcgatca
    78601 atagacctaa ttgtgccagg gtataatctt gtacttcatc aatcaataga tagcgaaatg
    78661 ctggtacatt taccttttca acaagtaaat gacgaatagc taatataatg actgcttcat
    78721 caacagtacg tgtgggttgc caagcataag ctgagccata tcgtttttca taaattcttt
    78781 caaacaactg atgctcatcc acccatgcca tttcttcgat ttgtctggtt atttttcgat
    78841 attttttttg taaaagtttc cttgcataag ctacaatact ttgttccgaa tcatcagaaa
    78901 tcaatttacc gaataattcc aactgcctat cttctgtcaa cgagagtacc tgattctgca
    78961 cagcaggact ttttgcttgt ttcaaaagat gattcttcca ttcgctcatc agtgcctttt
    79021 tcgttgcttg aagcctatcg atcaatttag gatgagcagg aactttctca tatatttttt
    79081 cgatcgtttt tttagaaagg actgtttttc catttttagt aagtccacgg ataaaattcg
    79141 gatgatctaa aaacaaagga tctgattgtt ttagattatc gataaacttt ttgctacgca
    79201 aacgttctgt ctgctccgat acattttctc ccgtgatacg tttgaaataa gcctcttcac
    79261 cttctatttc ctctgctgaa agctgtgaaa ccagctgtat gatggttaga ttcagtggat
    79321 ttctttcacc taatgatggt aggacattcg aaatatagtc gataaaccga tgattaggtg
    79381 atagaatcag caagtcatcg gatgtcatcg tatctcgata taaatagagc agatacgcaa
    79441 tacgctgcat gatagcagag gttttaccac ttcctgctac gccatttacc aagatatttt
    79501 gacttttcac atcccgaatg attgtgtttt gttccgattg gatcgtagca gtgatagcct
    79561 tcatttcatt ggtctcatct tggcctaaga cttctaataa tacgtcatct tgaatagcta
    79621 cagacgtatc aaaaaacttg accaaacgat ctctttccaa aagaaattgt cgtctttctt
    79681 taataaccgt atcgatttta ttttgacgaa ccgtataaga agatggacca atcatgttat
    79741 tgtaaaaaag ttcggcaatt ggtgaacgcc aatcataaac aagattttca tctgcatcat
    79801 ctgtgaaatt tgctgtaccg atataaaagg attcttttgg ctcattatcc agaaagtcta
    79861 caacgacttt tccaaagtag ggacttttca ataaacgttc gatctttgct agctgatttt
    79921 ctgcgttttt ctgtttgata ttcatctgat cgatttctct atttttcatt tcaatcatcg
    79981 aaaaagtatc caggttatct aagtaactgt caaaattcaa tcgaagctcg ccagccattt
    80041 ctttcaacga ctggtttcct tctatttttg ccgtatccat cgattcccgc agttcgtttt
    80101 ttttatcaat tagcttttga tacacgttct tcagatatgc ttcttctaac tgtttttgtg
    80161 tgttgaccat acacattctc ctcttttttt aaagtggtgg aaccgattag tttacctctt
    80221 ttaagagtcg aatgcaagct ttttaacgag tatcatttgt taggatatat cagttcttca
    80281 ggtcggacag tttgatataa agaaaatgca ccatcaaggt tttttacgtg gtagccagac
    80341 tgcttcaaga ttctttccgc tagatagcta cgtaatccgc tatgacagct gacgatatat
    80401 tcttgttggc tgtctaattc atttaatcgg tcccgaagtt cattcaaagg gatatgtttg
    80461 gcttccttga atttgccctt ttccaattct tctgctgttc gcacatctaa taaaattttt
    80521 ccttttgcta gttctgtcgg caattcatgc cattgtacgg tttcactaag cccttctgca
    80581 atgttcattg ctgcatatcc tagcatgttt actggatctt tggctgagcc aaatggcggt
    80641 gcatacgtca attctaattc cggtaaatcg aagatcgtca aatgcccttt gattgctgtt
    80701 gctaaaatat cgatccgttt atccacacct tttgccccaa caccttgtgc accataaatc
    80761 tcgccagtct ctggatggaa gatcaacttc agtaaaatat ctgttgcttc tggataatag
    80821 cttgcatgat cttttcctga tacatgaatg acttcaaaag acagttcgtt ttctttggct
    80881 gttctttcac ttaaaccggt ggatgcggca gtcattccaa acgttcgtat aattgctgtt
    80941 ccaataccgc cttgatttct tcgagaaatt ccggaaatcg tgtccgcaac ttgtctacct
    81001 tgacgattgg ctggtgaagc aagagaaata agtgcatctt ttccagtgat ttgctgtttt
    81061 acaacgatag catcccccac cgcataaata tcaggaatat tcgtttgata acgttcgtct
    81121 actaggatac ccccgcgtat gcctaattcg attccagcgg tcactgctag ctggttatca
    81181 ggacgaacac caatggataa aataactaaa tcagcaggga tggtacgccc atcatccagt
    81241 cgcaatcgtt tcccgtggtc ttcaaatcca gcgacagcat gagaagtaat cacttctact
    81301 ccttgatgag acaattcttt ttctataaaa gctgccattt cttcatccag tgttggaaga
    81361 atatgtggtg cttgttcgat caccatgact tctaaacctc ttctttttag gttttctgcc
    81421 atttccaatc cgatgaatcc tgcaccaacg atcacggcac gctttggctg tttttctaat
    81481 gcatgcatca ctttatcgat atctggtaca tttctaatag aaaaaacatt gtcggcttct
    81541 gttatccctg gaatcgatgg aacaactggt tttgcaccag gagataaaac caatgcatcg
    81601 tactgttcaa tgtgtttttg accctcatgt acgacttcta ccgttttgtt ttcgggaaag
    81661 atggctgtca cttcatgatt tggacgcaca tctaaacaaa aacgagcgga taatgattct
    81721 ggcgtttgga caagaagatt ttcccgttca ctgatttctc ccgaaagata ataaggcaag
    81781 ccgcaatttg caaaagaaac atacggtcct ttttcaaaaa caacgatttc tgcatcttcc
    81841 attaatcggc gaagccgtgt agcagcagac attccacctg ctacacctcc gacaataacg
    81901 attttcatct tatttccctc ctactgttcg atcaaaccat tgattcatgc caccacgtac
    81961 attcactaca tcataaccag atttctttaa ttctttagct gcttgtttac tcctcatccc
    82021 tgattgacaa atcacataga cggtcttttc tttgtctcca tcatatctgt ttatactttg
    82081 taatggaaca tttttagctc cttttatatg cccgccccgg tattctgcag gtgttctaac
    82141 atcaagtaac gctggatttt ccaaaagctt ttcctttaat tctgggactg ttatcgattt
    82201 tattgattga aatagcaaat tcattttctg cacctcattt acatttttat aaatacctca
    82261 tggggtatat taaacaggag ctttattaat atgtcaacca gaatgactct tcattttttt
    82321 cactactttt tatatttgca taaaataccg ataaggggta ttatctaatt ataaaaatag
    82381 aggagaatgt gttatggaga ttgataataa aaatatcctg aaccgtttga aacgtacaga
    82441 gggacaaatt cgtggtatcc aaaaaatgat cgaagacgaa aaagaatgta tggatgtcat
    82501 cactcaatta agcgctgttc gttctagtat tgatcgcgta atgggcatga tcgttgcaga
    82561 taatctgaaa aattgctttg agaaacctga tagtaatcca gaagaacaag cggctaaact
    82621 agaacaagcg atcaagatga ttattaaaaa gtaaaggaat gatttcaatg aaagtcgttt
    82681 tccatattga tgaattagaa aaatggtcag aaacagggaa aaacgtaaaa aacctgataa
    82741 aagcttctcc agaaacgacg attgtcgtat ctgtaaatgg catcgcgatt accggttatc
    82801 tagactctgc caatgcagaa ttcttagatt tgcaaggagt cgtttttcac gcttgcgcca
    82861 atgctatgcg tgctaatcat atttcagaaa gttctttacc tgaacaagta atcgttgtac
    82921 cagcaggtgt ccttgattta gttgaactgc aatcccaagg ttatgcttat atcaagcctt
    82981 agtcagtaga ggttgcgaca gaagtgatca gcttcaagaa atttcggctt atttttcgaa
    83041 gaagctactt ctggaaaacc gtgaatcaaa ggttgtgaaa acgctgtcct gcatcaagta
    83101 ataagaacag ccaaacaaaa atagcttctc atatttttcg tttggttggg cttattaccg
    83161 cagatgcaag cttttgaaca ccgtttaagg aagaggttgt gaaatcagcg gtttgaccta
    83221 agtattagag aaaaaaacgg gaaaatagct cctcatattt tgccgttttt tgagctaata
    83281 ccgaaggtca gctgattgaa caccgtttaa ggaagagatt gtgaaaaagt cgcttagttt
    83341 cgagtattaa gaaaaatttt gtaaaaatgg atttctacat ttttgcataa atttggctta
    83401 ataccgagaa actggctttt gaataccgtt taaggaagag gttgtaaaat cagcggtttg
    83461 acctgagtat tagagaaaca aacggaaaaa tagctgctca tattttgccg ttttttgagc
    83521 taataccgaa ggtcagctga ttgaacaccg tttaccaaga ggttgtgagc ctaccattta
    83581 actccgaatc acaagaaata atttcaaaaa caacttctcc tgtttttggt tcggttggct
    83641 tattatcgag aagtagctac tgggagtcta tttatcaaaa aaaggaatgc gacataggtc
    83701 acaccccttt tttattttct ttgaaacatc tttcggtact cgacagcata caagacaaaa
    83761 gattgtaaaa gaccgtaagt gatgacggca aaaatgactc tcacccacag cgttggtaat
    83821 tctgggaaaa gcagcaaaag gatcatgcca acatagatga cagcagtcgc tactttgcca
    83881 taccacttcg ctccacttaa tttgatattt ttagatagcc cgattaatcc agctacaaac
    83941 ataaagcctt cttttatcaa gaatagacca aacaacagcc aaagccacgg tcgataccat
    84001 gccatagaca aaatcagaaa aagttgtgtc aatttatctg caaacggatc aagcaccttc
    84061 cctaagtctg ttacctgatt atatctccga gcaatgaccc cgtctagata atcagacaaa
    84121 cctgagacaa caatgaccgc tcctgctata taaaatgact gtctcagcac aaaataaaga
    84181 taaatcggca gcaaaaaaat acggaatatc gataaaagat tcggaatcgt ttgtatttct
    84241 ttacgccagt ctgtgcttaa tttcatttta tcgccctacc tcctcagcac tcttttcttt
    84301 ttattttagc ttacacgggg aataaaacca atgatttcac tgtttttatt tttctttaca
    84361 gacactgata ttatgagcta atttgagata atcacttgct gttttcatcg tttactcttc
    84421 tttcttcctg tcgtttgcgc atttctttta ctagtacttt atgagctttt tttgatcctc
    84481 gctctaggtc acgctgccgt ttacgtgttt tataatcgat aaacagactg tctaaatcgt
    84541 aacctgtcgg gtacagatct tctgctgaac gcaccagacg aacacgctga cgaggcacgt
    84601 ggattatttt tttgtctaaa tatacatcaa tcgtatcttc acctatatct tcataaacta
    84661 acgcttcttt ttggtattca ttgacaaata tccgatcacc ttttgcaaag agctgacgtt
    84721 cttttttatt ctccttccta tttgtaactg ctgtcttagg aagaaattct tttttctgtg
    84781 tccgataggc tttttccgcc aagtaacgct ctgcttgatg gatcaatttc atcgacatat
    84841 ccattttatg agcaatccac aaagcttggc tttctcctgt ttcttccaac ccgcaactga
    84901 tatttaggac gaagtgcttc ccgatcgaaa gccatagcag ccggcacaaa atcttcatga
    84961 tctccggcga atttcttgat ttctccataa tgggtcgtgg caatgatcaa tgccccttgc
    85021 tcatacatag attccatgat tgcgatcgct agtgcagccc cttcatttgg ctctgttcca
    85081 ctgccaatct catctaaaag taccaacgta ttccttttta tctttttcaa aatagcagcg
    85141 atgttttgca tatgaccaga aaatgtactc aacgcatttt ctaaattttg gtggtcaccg
    85201 acatcgacga aaatctcatc aaagacagca agctctgtcc cttcttttgc cggaacttgc
    85261 ataccgaaca tcgccatcaa agtcaataaa ccgactgtct tcaacacgac tgttttgcct
    85321 ccggcatttg ctccggtgat aatcaagcct cgatagtctt taccgatttc aacatccaat
    85381 ggtaccgcat gctcaggtaa aaatggatgt ctgccttgct tgataatgat atgttccgat
    85441 ttattgattc taggtgtgct tccattgatt tctcggctaa attttgcccg agcaaagatg
    85501 atatctaaca ccgtgatcgt ttcgatcaat aaatcgatca cttcttcgtt ttctgcgata
    85561 gcaccagtca atgccgccag gacttgatat tcttcactga tttcttcagc ttttaacaac
    85621 tgatagtgtt cattcaattt agaaatcaca gttggttcaa taaaaaccgt cgttctttta
    85681 tttgattcat cgataatcgt tccatctatt ttatttttat agctggcttt gataggaatc
    85741 gtatagtatt cgcctttttg aacaatcatt gcttcttgga tcatttcttt gtttttcgga
    85801 tgacgcaaga atttcagtaa ttttgactgg atttcttttt cgattagttg taattgtttg
    85861 cgtactttac gcaaattacg tgacgcgtcg tcactgactt tattattttt tattttctgg
    85921 tcaatcaact cttctacatt tatcaaatca ggaagatgtt tgctataagc aaacaacaag
    85981 ggtgtctggt attgattctt atcaaaaaac tttgtgatca tccgactgct tctaagaaaa
    86041 tccgcatatt cgatcaaatc ggttggctgc agaatcaacc cttttttgac ttgttctgtc
    86101 agtgcatcga tcctcggcaa ccccataaat ggaacatgct gactgctttc taagatcaag
    86161 cgtgcttctc ttgtttcttc ttgacgatcc aagacagttt gtaggtttgt cgagaccgtc
    86221 atatcgctga ttcgtttttt gctatagttt ccaattgctc ttgcttggat ttcctttttg
    86281 atccgatcaa attgtaattg actaatcatt tcgttgtcca tattctctcc ttttcttgaa
    86341 gagatacctg tcccaaaata aataagggcc tagagataaa taaaaggata gaacacagct
    86401 taaaaaagtc atgtcctatc cttattagaa tacaaagata ttgttttcct gacaggtacc
    86461 gtttcataag cacaccaaat aaactttgtt tattggctat tcgacttact gattagatac
    86521 cagctacact cacaaaacat accccattct tctaggtctt atttattttc cacttaacta
    86581 tagcaagaca cattttggtt gtcaaacttt agtatgtttt atagatttac accattaatg
    86641 aatagacacc taccgcgata attgctccga tcattggacc tgcgattggt acccatgaat
    86701 atgcccaatc tgaagttcct ttattagcta ttggcaatac cgcatgtgct aatcgaggac
    86761 caaagtcccg agcagggttg attgcatatc ctgttggccc tcctaatgaa agaccgatgg
    86821 ctaagatcaa tccacctaca gcgaatacgt tcgttccagg tgcaaattcg ttttgtccaa
    86881 aagctagcaa cccaagaact aatacaaatg taccaattaa ttctgtgatc acatttgctg
    86941 gataattccg tatagcagga cctgttgcaa acgttcctaa aatcgcgctt tcatctttcg
    87001 ttgcattcca atgtggcaaa taagaaagcc aaacaagaat ggcccctgca aaagctccta
    87061 aaacttgcgc aatgatgaaa ggaacgacaa gattccaact aattgcccct gtcatcgcca
    87121 tagctagaga gactgcagga ttcaaatgag ctgggcccat gaatccagaa atatagacag
    87181 ccattgttac agcgagtccc caaccaaatg cgatgacaat ccagccagaa gcctgtgctt
    87241 tacttttgtt taaattcaca gccgcacaca caccatctcc aagcaaaact aggatcagtg
    87301 tcccaataaa ctcccccatg atttgagtca tatcactgtt catttatttc tcccccttta
    87361 gttcccgcag atctgattct gcaatcaatg cttctaaacg tttagtctgt tgcgccttct
    87421 cctcttctgt ccattcaaaa tatccagcaa ttgcatcgat cacaggttgc ttgatctcat
    87481 caagctgatc tcgttcaaac aacagatgat ttgtacgacg aatgagataa tcgcctgggg
    87541 ccaaaaccat ttcttcttct aaaccataac gtaaccgagc tgactcagcg agactcaaac
    87601 caggataagg tgccatttct tttgctaatt caaagatacg tcgggcatta gtcccgtaaa
    87661 aatcagcgat ataagtagca tcttcttcct ctaaaccggc tgctactcct tcttttgcta
    87721 attctgtcac tgtttcttct aatttagttg gatcgaagtt tccacctgaa atctgatatt
    87781 ttttagagtc gatttctttc gtctctattc cgtattcttc ttttaataat tggcgtatca
    87841 atcgcaaagc tccttctgcc atcttacggt aatcggtgat tttcccacca gataaagtca
    87901 gcaaaccatc tggttctctt tctaaagaac tacctctgga aatcgtagaa ggtgcttttt
    87961 catcacggct gttttccaaa tggttcaaca cgtcttctac ttcagcacga gaaactttgt
    88021 tttccttata ttcacttact gtatcgacaa ctttattgaa gctcttgtct gaaatcgatc
    88081 cattatctcc accattgtaa tcagaaccag aattaccaat caacagtgga cgaagtcctg
    88141 cccagcttgc ttcgatatca ttcaatgtga tatttgcttc tggatagcga tgattgatca
    88201 catccaatag ataatctaca tcttcttgtg tgactttcgg atccgtaaaa tctccttggt
    88261 aatccgtatc tgtcgtacca aagtaagtct tgttttctct tggaatagca aaaaccatcc
    88321 gcccatcttg ctttcctgta tcgaagtatg tgggttgcgg tacaggcagt tttttcgcat
    88381 ctacaactaa atggatccct ttagttggac gcattttagg agagactgga cgcgtaaaat
    88441 tcaagtttcg tactttatct acccaaggac cactcgtatt gatcactaat tttgctttga
    88501 tttcgatcac ttcatctgtc agcaggtcac gagctttgac gccaacgatt tgatcgccat
    88561 catataaaaa gccaaccgct ttcattttac ttactagata agccccatct tcggcagcct
    88621 ttttgatatt atcaatcact aaacgggcat cattgttgcg gaaatctaga tagacacccg
    88681 cgccttttag cccttctttt ttcaaaaacg gttctctttc caatacttct tctggtgtca
    88741 gcgtataatt ctcatatttg gttcctgtca catttgccag tttgtcataa aggtccattg
    88801 ctactttgac cgagaacata ttgaaggttg ttgctccttc gccctcatag attggcaaaa
    88861 gcattggatc tggttttggg atgtgtgggg caatactttg tacgactgca cgttcaccaa
    88921 ctgtgtcagc tactacttcc acatcaaatg tcttcagata acgaataccg ccatgaacaa
    88981 gtttggtcga gcgagaggaa gtcccttctg caaaatcctg catttcgatc aatcctgttt
    89041 tgattcctga tgctgctgac tggactgcca caccggcacc agtgattccg ccaccgatga
    89101 tcaacagatc caattcttct tgctgcattt tttgaatgct atcttgtctt gtcttgtttg
    89161 aaaacatatg gatttcctcc ttattcaaat gcttgggtag cttttactgc ttttttccaa
    89221 ccgttgtaaa gtttttctcg gcgctcttcc tccatttgaa cttcaaatag cttgccagct
    89281 tcataaaatt cgcggatctc gtctgtatct ttccaataac cgacagctaa tcctgctaaa
    89341 aatgctgccc ctagcgccgt tgtttccaag ttttctgctc gttggatcgg tacattcaag
    89401 atatctgttt ggaattgcat cagatattca ttgtttgctg caccgccatc tactttcaat
    89461 acaggaatct tgattccagt gtcatcttgc atcgtatcga tgatatctct cacttgataa
    89521 gcaatcgact gtaaagtagc tttaatgata tcttcttttg tcgtaccacg tgtcaagcca
    89581 aacatagccc ctcgtgctgc ctgatcccaa taaggagcac ctagcccaac gaatgcagga
    89641 acaacataaa cctcatcttc gcttgtagag cgtttcgctg cgtcttctga atcgctagct
    89701 ttttgcaaca tttgaagtcc atctctcagc cattgaatcg aagaaccagc cacaaaaata
    89761 cttccttcta aagcatagta aacctttcca tttatgccgt aaccaattgt cgtcaataaa
    89821 ttatttttgg ataattgcgg tttttcaccg gtattcatga caataaatga acctgtacca
    89881 taagtattct tgaccatgcc tggttcgaat gccatttgtc cgaataatgc ggcttgctgg
    89941 tctcctgcca tccctgaaat tggtgcttcg cttccataaa aatgataacc ttgcgtataa
    90001 ccataaactt ctgagttaga agtgactttt ggtaacatca ctcgaggaat atttagtaaa
    90061 tctaaaatct cctgatccca atctagctga tggatattga acaacatcgt ccgactggca
    90121 ttcgagtaat cagtaacatg tgcttgtcca tcggtcagtt tccatactaa ccaagaatcg
    90181 atcgttccaa acatcaattc gcctttttca gctcgttctt gcgcgccttc tacatgatca
    90241 agaatccagc gtatcttcgt tgctgagaaa taggcatcga tcactaaccc tgttttttcg
    90301 tggaaaaatt cttgatagcc ttcatttttt aagttatctg caattccagc tgactgtctg
    90361 gattgccaaa caactgcatg atagattgga cgtcctgtat ctttttccca tattactgtt
    90421 gtttcacgct ggttcgttat gccaatccca gcaatctgat ttggtttgat ccctgattcg
    90481 atgaacgctc cggcaataac tgactgtaca gaattccaga tttcatttgc atcatgttcc
    90541 acccaacttt cttgcgggaa atattgcgtg aactcttttt gagaactgcc gatgtgtctt
    90601 cctttcttgt caaagataat tgctcgtgag ctagttgtac cttggtcaat cgccatgata
    90661 tacgttgatt ctgtcattgt gattccctcc attatatgca aacgctttct ttaactactc
    90721 ttatcatact actgttttaa aaaaagaaac tgtcaaaatt ttattctttt tttctttttt
    90781 tgacagtttt ttattatgaa gctatttttt aatcaattct tttctttttt cagcgtctct
    90841 attcttcttt tcaatcgaat aatgtcgtaa ggtgacgcaa attctgacag ataatattca
    90901 cactgttttt tgtttctctg gcaaaatgtg atcaccaaat catattcttt accttcttca
    90961 taacttccaa tctcaatacc gccgattccc ctcagttctc tgatcagata ttgttgaaaa
    91021 gcaatacgat aaatcggcag actttctaaa tcgattccaa tcactactgg ttttgcaata
    91081 taaaaatcga tcatcaaaag aacattggca tactggatca tcaggtaact aagctcacta
    91141 tcttcagctc ttttcctcgg caattgctgc accgctgttt cctgtaattt cgccagtaac
    91201 tgtgttaagg aatgcccgag cattttctgc tgctgttcca aaagccgatc acgctcatag
    91261 acttcgatct ttccaacaaa gaaaaaccat tcattgttga tctgggaaat ttggtagcct
    91321 actgcctttt cttctttgat tttcaaacga cgaggacgat aatgccataa catcgtttcc
    91381 cgaatgtaag tatctaaaac agcggttggt aactttttgc tccgtgtcaa atcatactga
    91441 taaaatattt cttcgtctac tatcgaaaaa gaaacaaaaa agctgtaaaa catcattgtt
    91501 tcgtatacat tcagttctgc tgctgttcga ctaagatgca tcacgatgat tggatcgatt
    91561 gcttgataaa gccggtccga ctgatagagt aatttctttt ctttcaaagt tgcgtacgta
    91621 cttttttcat tcaatagtct ttttttcgta atcccgagcc agcaagcaat ctgtgcttct
    91681 gctgatgccg taaacgttgt ttctaataca cggtccaatc ctagaatgaa cggtcttttt
    91741 tctggtgtat tttgcaaaaa aagcggtcgc tgatcttccg ggatatattg gaatagttca
    91801 taataaaaat atcgtatctg tagctcttct ccgtataatt gaccgttttt gatttgtaat
    91861 ccaaattcct ctaagagctg gttcaattct ttgatctttc gaaaaacaga agactcactg
    91921 atattaaacg ctgtcgctaa tcgaacgatg gatacttgct gatgttctaa taaatagacg
    91981 agcatcttaa acttcaagct ttcctgcaat aaaaacaata gaattttttc caaacttaca
    92041 tcttcgtcca acacaagcag cgcctgatac tcatttcgct gtacttctac ttttttttcc
    92101 atcattcggc caatcaattc aatatcttcc aaatattgat caaacgaggc ttttgacagt
    92161 tggacatgct ctctcaaacc attgatagag gctgttcccc cttgcagaac aaggtttcgc
    92221 aaaatcagga tctgtaactg ctcttttctt tctaataatg cttcaatctt cataggcagt
    92281 attcgccacc tttgaccaca ccatatctgg cacacggtat tctggctgga aaaatagctc
    92341 atgttcttct aactgttcaa acgtccatcc ttcttctact gcaattgtca gttggtcaag
    92401 aaggtggaac atctcttttt tgctttggag ctgtgctcca agaatctttt tttcagaatc
    92461 aaatagaaat ttgagtttaa ctttgctttg atttattgct gtaagcttgt agtctacgta
    92521 tcctgtttca attttttggg gataaaaaat gctctcttct tctgtcaaac ctacgcttcc
    92581 taagaaatag ccaaaccact gattgccgac tggacgatag gttccctgat cctttgtctg
    92641 tgagccacta attgtcttgc tgacatttcg tgctgtacgg acagcgttat ttactagaga
    92701 aacatacatt ttttcatttg ttggacgaaa agttacttgg atcgcatcgc caatcgcata
    92761 aacgtctttt tgagacgttt gcaagtagtc atctacccag atcgttccat catcattcaa
    92821 tgttaattgt tcttcccaca tctgattgtc gggacgagaa tgattagcca gcaaaacaag
    92881 atcatagttc tcctttcttt tttccgtctc tacaatagcg gtttcatttt cggtcaaaga
    92941 cacaacttgt tcttctaaaa aaagtgaaag cccttgattt ttcatttcct ttactaacgg
    93001 ttctgtcatt tcaggatcta gataacgaaa aagaattgac tttcggcttt cgtaaagatg
    93061 gatttgtttt tttcttgatg ccaacccttc agctatttcg attcctgctt gtcctgcacc
    93121 aataattgca attttctttg cattcatgat cttttgctga agagccgtta cgttttgtat
    93181 ctttttaact gggtgaataa gcgttgattc tgcagaaata tttcgaaact tttgatttga
    93241 accagtcgct agaatcaaac gatcaaaatc caattttttt cctcctgcta aaacgacttt
    93301 tttttctttc aatcctatta ctgtcttttc tgtgtaaaca tggattcgat agcggtcagt
    93361 cagttcttct ttcgtgatcc aagaaagttg tttttcactg gtaacctttc cttttaatat
    93421 caaattgaac ccgctgggaa tccatcctaa cttcgattgc ttttcaatca aatatatttc
    93481 acttgttggc atcaattggc gaagataaat agccgcatga atccctgcaa acgacccgcc
    93541 gacaattaca atgttcatct gcattcctct ttcttataag gtgttctact gctaacttct
    93601 caatcagaaa acacagtatt cataactcgc tttcaacctt atgatacata gcgatgcagc
    93661 agaatcaacc ctctccatca taccgtgttc taggtctgct tctcaataat gtactagtgg
    93721 acctaattga agagtatcat ttctgaagag atgtttcaaa aaatgtactc ttataaaaga
    93781 aaaaaactcg ccttttacgt acctctgtcc aaataggaaa cagaaaagaa cgaaaagacg
    93841 agttttagcg tgtgtaatgt aatagttaga atagacacat catttatttt taattcttta
    93901 atgcttcaac aactgcttcg cctaattgat gagcagattg aggattttgc cctgtaagaa
    93961 gccgcccatc aatttgaacc acttctgaaa aagctgctcc agactgatag tttgctcctt
    94021 tttctttcaa agcatcttct gctaagaatg gtacttcatt cgttgtacca tttgcttcct
    94081 cttcttcatt actgaaccca gtcactgtac gtccagctaa aatagatttt ccagactcat
    94141 ctgtaactgg caacaatcct acaacaccgt gacaaacagc tgagaccagc ccttcatttc
    94201 gatagatttg tgaagcgact ttcccaagat ctattgcttc tggaaaatcc cacattgttc
    94261 cgtggccacc agcataataa accgctgcat aatcatttgc atccacatca tcaggacgta
    94321 aggtatttcc caaggcccga tttctgaaat cttcatcttc ataataggcc caatcgattt
    94381 catccatatt caaaacactt tgcggttcta aaggtacata tccgccttta ggactgacaa
    94441 aatctgcatc gatcccattt tttactaata catcataaaa atgagtcagt tcacttaacc
    94501 acaaacctgt aggacgctcg atcttttcgt acttttctac atttgttaat acgatcaata
    94561 ctttcatttt cccatcctct ttctataaaa attgcgttat tgataacgtg ctttcaagaa
    94621 attatataat gggcttggca aataaagctc tttatatgct tcttcaaaag gtttcgttac
    94681 aaattcatcc tcacggtttt ccaataattt ctctgcccag tcaggatcga cgatcatttg
    94741 ctgtccaatt gctgcaagtt ctgcatattt caatacctgc tctacatctt cgcgattgcg
    94801 gatcccaccg acaccaacta aagggatctt tccttgaatc gtgttatgga ccacttcaag
    94861 aatcgattta tcgttgtatt tatcagaacg agctattcga tcatacatat ttaatgaaac
    94921 atgcagataa tctagttttg actcacgtaa tcgttcaaga agccagatcg tgtcttcaaa
    94981 acggatacct ggtgtttcat attcttctgg tgagaaacga taccctacga tgaatggttt
    95041 tttagcatat tgttcaaccg ctgagaaaac cgttgttaat aattcttcaa taaaacgata
    95101 acgattttcc aagctaccgc cccattgatc ctctcgtcta ttcgaatgcg gagagaaaaa
    95161 ttgttggatc aaatacgtat ttgctccatg caactcgatt ccatcaaatc ctgattcaat
    95221 cgctctacgt gtggctttgc caaatgcttg gattgtttca acgatttctt cttcactcat
    95281 tgctcgtggt gtttccgcat caggacgttt tgctgcaact gcacttgcag atacaggctg
    95341 ttctccagat aaagttgctc gacttgtcat tcgtccaccg tggaaaatct gaataatcgc
    95401 ttttgcgcct tctccttgga ttgctttcgc tagctcactt aatcgaggaa tcatttcatc
    95461 atgagcgatg ctgagttcac ctggccagcc ttttccgata tcttggacat ttgcagcacc
    95521 agtaataaca gcaccaagac ctttagaacg ttgtttataa taagtgatct catcttcggt
    95581 gatcactcca ttgaaaaagc tgagttgtgt cgtcataggc gacagcatca atcggttctt
    95641 caattgaact cctgaaggta aagtaattga ttgatcaaat tgtgacattg tcattcctcc
    95701 cataattcgc tctgattaac ctatcgagaa tcatctatca ttaaaccact cgattagttg
    95761 tacatgcaac taatttgctt aaaaaatttt attttttttg taacttatct gttgcatcat
    95821 tcattgtctg ggctaattct ttacttgctt catttcccaa aactgctttg tatgactgat
    95881 gaagttcttc ccagctacca tcgacttcct tagcaaattg gcgtccttgt tctgtaagat
    95941 aaactaatga caagcgacct tcgctaactg ttttgacgta tcctttatat tctaattttt
    96001 caacaaaacg agcaatcgtt gatggggcgg aatagagcat ttgtgcaata tctttttgtg
    96061 gtattccatc tttttctttt aatatcaata aaataaaacc ataagttggt gccagacctg
    96121 tccttctaaa cgcttcatca gctaatttat tcaacatgcg atctagcttt ttcacgctaa
    96181 agaaaagaca ttcatctaac gctttttcaa ttggcttttc catttcatcc cctccattgg
    96241 cgtacatatc atagtatgat ttttattttt tgtcaaaaaa cacggaataa tgtccgcctc
    96301 ctctgtctag atttgaaaaa aagaagtagc catcttcaaa gaatttcggc ttgttttcga
    96361 caaaactcct tctggaacac cgtgaatcag aggttgtgaa aaagtcgttt agttttgagt
    96421 atgaagaaaa attttgtgaa aatggctttc cacatttttg cataaatttg gcttaatacc
    96481 gaaaaactgg cttttgaaca ccgtttatat cagaggttgt gaaaaagccg tcctgcatca
    96541 agtaataaga acagccaaac aaaaatagtt cctcatattt tgtcgttttt tgagctaatg
    96601 ccgatggtca gctgattgta caccgtttat tgagaggtcg tgagcctgcc gttgaactcc
    96661 gagtcacaag gagcaatttc aaaaaacagc ttctcatgtt ttatgactat ggtgacttgt
    96721 gatcgaggag ttggcaggag aatactgttt attcgtaaag aaggggctgt gacaagactt
    96781 ttgtcacagt cccttatttc cttttattat aggatttcgc catttgattg gatgacttgt
    96841 ctgtaccaat caaatgattt tttctttaac cgtttctttg tgccattccc ttcgtcatct
    96901 tgatcaacat agatatatcc ataacgtttt gacatttgtg aagtagaagc gctgacgata
    96961 tcaatgcagc cccacgacgt ataaccaaat aaatctactc catctttgat agcttccttc
    97021 atctgctcaa tatgctgctt caaatagtca atgcggtaat cgtcttgaac ggttccatct
    97081 tcttctactt tgtctatagc tccgagtccg ttttcagcta tgaacagtgg tttttgatac
    97141 ctatcatata attgattcaa agcaattctc aaacccttag gatcaatctg ccagccccat
    97201 tcacttgatg gaagatacgg atttttaatt cctccagtta ttaagtttcc ttggacccct
    97261 tcccaatttt ctggatgagc actgactgca ctagacatgt agtagctaaa agaaacaaaa
    97321 tcaacagggt aggctgctaa gatttcttca tcacctactt ctatttttaa gttgacacct
    97381 ttttcttcaa acattcgttg cgtatacgct ggataatatc ctcttgcttg aacatcacta
    97441 aagaacaaag aagttctttg ctgctcaatt gttttttgaa tatcatccgg atcacaagaa
    97501 tacggaacaa gaagctgata gctgatcata caaccgactt gtgaaccttt gataatttca
    97561 tgacaagctt ttgtagctaa agcacttgct ataaactgat ggtgtgcacc ttggtatttc
    97621 gcttgttcca aatggggatg gttttcttca attactccta cgctaacaaa agggtgatgt
    97681 tttacacagt tgatctcatt gaaagtcatc caatatttta ctttattttt atagcgtttg
    97741 aatactgttt cagcgaaacg aacgtaaaac tgaataagct ttcgattagg ccatccacca
    97801 tattctgtaa ccaaatataa cggcatttca taatgggaaa gagaaacgac tggctcaatc
    97861 ccatatttta gacattcgtc aaacacttga tcataaaaaa ataatcccgc ttcattgggt
    97921 gtttcttcat caccatgagg aaaaattctt gtccatgcga tagacatccg atagcattta
    97981 aaacccattt cagcaaataa acggatgtct tctttaaagt gatgatagaa atcatttccg
    98041 tgtcttttag gataataata cttgctgttg ggatcctgcg ccgcttttac ttgctgatgc
    98101 gtcatcatat gccattgatc tgtccatttt tctttaggta aatcgctgtc gaatgtatac
    98161 acatcagaca cagataatcc tttttcatct acatcccatg caccttcaca ttgattggcc
    98221 gctgtcgctc cgccccataa aaatccttct ggaaattttt tcatatcgat ccccctaaac
    98281 ttgctagttt tcttgtttga ttatttttct tatgactagt aatgatattt ttgaatctac
    98341 tactatttgt aacaataacc attgtggtcg gatcatatcc ctctttgatt aattcttgca
    98401 aatctacttc catcaataaa tcgcctttac gtactttttt tccatcagat actgcacttt
    98461 gaaagtattt gccatttaaa ttcactgtat caataccgat atggatcagt atctctgctc
    98521 cttcttcact gactacccca attgcatgtt tcgttggaaa aactgttgaa acttccccgt
    98581 ttacagaact gtagattttt ccgtccgttg gaatgatcgc aaacccttct cctaaagatc
    98641 cactagcaaa tgttggatcg tttacttcag ataaatcaat tatttcacct gctgcaggag
    98701 tacttaacac tatatccttt gaggattctt cttcgatttc atccttgtag ccgaaaagaa
    98761 aagttagcat acaggaactg atcatcgcta agaaataact agcaactagc caaacaaatc
    98821 cttcaccaat ataaatcggg aaagacaaaa tacttcttgt agcaactgcc aaagcaccgg
    98881 ctcctgcggc accagctact ccaccaaata tagctccaca tatacaagca atgtaaaatg
    98941 gtcgtttata tttaagagtc acaccataaa cagcaggttc agtgattcca aataatgctg
    99001 tgataaatgc agataaagat aaacttttta ctttcttatt tttcgttttc aaaaataccc
    99061 caagtactgc tcctgcttgc gcagctacgg cagtcataca tgctggacct agcgtatcac
    99121 gaccgtagaa agaaagattg ttggtcatta ctggtacaag tccccaatgt aacccaaaaa
    99181 tcactaacac ttgccaaaat ccgccgataa cagcaccaga taaaacaggg ctaaagttat
    99241 aaacagctaa atatccagct gcaatcagct gacttgcata atctgcaatt ggacctacaa
    99301 ctaataaaat aattgggacc atcacgatga tacaaatgaa tggtgtcaat aaatttcgaa
    99361 tactttcgtg caagcttttg cgaatcttag gctcaatata agaaagaacc catacagcta
    99421 aaattgctgg aataaccgta cttgtatacc ttgctagaat cacgggcatc cctagaaatc
    99481 gcaaggttat gctatcacta tatgcactga caatcgtagg ataaacgaga gctgctgcaa
    99541 taaccatagc gatgaaacga tctgtattga acttttttgc agcagtatat gccaaaaata
    99601 taggcaagaa atagaaaaat gcatcagctg ctgcattcaa aatgatataa gttcctgatt
    99661 cagtagttaa taaattcaaa ctcgtacata aggcgagtac tcctttgatc aaaccacttc
    99721 ctgccaagac gcctaaagtc ggggcaaaaa cagcggcgat catgtctata aaagagttta
    99781 aaatgccttt tttctcagtt cctctctttc cactagatgc atcatcttct agtttcattt
    99841 gtttggataa tacgtcatac acttcattta ctgcatttcc tactacgact tgaaacattc
    99901 ctccagcttc gactacagtg atcacacctt ctagttgctc taccttctcc ttatctgcct
    99961 tcttattatc ttttagggta aagcgtaacc ttgttgcaca atggtaaaca ttgctgacat
   100021 tttcttcgcc tccgacaaat cggacaatat ctttcgctaa ttgtgaatag tccattttta
   100081 cttccccctt gttaattaat gccgtagcaa tccttcttac aagataagta tagttcttag
   100141 aaaacggttt ctccattcaa ttagtacccc ttctaatagc gaacgaaact gtacaatagt
   100201 gtgtatggtt tacttagccg agcaaatcac tcactgcttg aaagaaaaca agtatatcgt
   100261 ttctcttata gtcaaaggag acaaaaaaaa cacgcttgat cttcctttgc tgatgtataa
   100321 gtggtatctc aagctgatac tctgtgattt ttgtttctac ttggcttttg ataagacagc
   100381 acaacaaagt ctcggcattt aacggaagca taactaggtc agaactagga gagattagtt
   100441 gctgaatgga atctatcttt ttatggattt ttatttgatt ttcttctttg tagtaatgat
   100501 caagcagttt tgttttcttt ttttcttcaa ctatggtcag cttttcacgc aaaatctgat
   100561 aaatctccca agattcaaac tcatctagaa cactaggtag ataaatcaaa tcatcccact
   100621 caaaaataag ctcttgctca gtagtcaaaa ttgcatcata ttccgttatt ttgtttgatt
   100681 gatttttgaa aagatacact ggttctatcc ggcattcttt gatccacatg ttcatacttt
   100741 gttgaatctg tttttttagt gtattcaaaa tactaattgg ctggttacta acaatcagta
   100801 tctccccttg ttttcgaaaa ggattcaacg cttcggcaag atacaaaaca aaataagcgc
   100861 tttcagctaa attgggacgt aattgaaaat gtattgggaa gaaacgccga attaaataaa
   100921 tttctaaagg ataacgggag atgatctttt gtacaaaatg attcatggta ttatgtccgg
   100981 catccatcct cgttttcatt tgtttgatat gggttagcaa aaattctgtt tcatggaaca
   101041 ataacgaaac aggaagatct aaaaaacgaa taatcgtttg ctcaaatgct cttagattct
   101101 tctctatttc tttgtttttt tcatcattaa tcatcaaata atttaactct aatagtcgat
   101161 tttcaattgc ttgtttttct tgattggaaa aagaataggg tagttctgat gataactttt
   101221 ttgtgagggt ctctaccatc ggaataaata atgtatacct gtttgttttt tctaaaagtt
   101281 cttctcttcg aagaatggtc aaaacgagat accgagaaaa tcgtatgaag tcctctcctg
   101341 aaacaatata attatatgat ataagaacct cttttaatgt cttttggaca gtcggcatga
   101401 tattggaaaa aattgtactg atttgttgag gcaaccttgc gtgttggatc accgtttctg
   101461 ttccaacaag agataagaaa attctttttg aattttcttc agcaatgatt tttagtcctt
   101521 ttgtcgacga aacttccagt tctaatttag gattgcgctc gatccaacgc aaaatcgttt
   101581 ttatttgtaa tgatacggct gtttttgaaa gaaagaaaat gtctgctatc ttttgcatac
   101641 tgacataccc tttttgaaac aataagtacg tcacaatagt tgaagctcgg aaatccatgc
   101701 tggaatagat tttatgtttc gtcacctctt gtatgatttg ctgtttagtt tcagattcaa
   101761 ttgattctaa aaaataacct gaacgtttat ttgactggat aatgattttc ttctcgtaga
   101821 tagcaagcat atttttgatt tcagtttgga tcgttttctt gttggtacct aaagcttcag
   101881 ctaattcttc gcttgttatc caatgattct tatttcttaa tactacaaga atttggagtt
   101941 gtcgtttatt taagtccatt tgcttacacc tcctctttgt tataaacata caggaaaaac
   102001 ctctcaaatg acaatagtca cttgcagagg tttaaaaatc atttgaagaa agatctatat
   102061 tcaaggtttt taccattaga ctggataatt tgtttataat attcaaaact atcttttttc
   102121 aatctcctaa agcttccgct cccatcattt tgtctatcca cataaataaa gccatatcgc
   102181 ttcctcattt cccctgttcc tgccgatacg atatcgattg gtccccacca taagtaacca
   102241 atgatttggc aaccatcttt tattgcctca gcaatttcct gaagatgtat ttttagatac
   102301 tcacaacgtt ttggatcgtg gattcgattc aattcatctg gtgcttcatc tagtccaatg
   102361 ccattttcaa ctatgaataa tggtaattca taacggtctg tcaattcatt catgacataa
   102421 cgaaacccta gaggatcaat tggccaactc caaggttcgg gagatttttc cttcaaaaag
   102481 ggattatcga aaccatttgc tccgccagta tctacgcgca tttctgcttc ttttttatag
   102541 acagcgctac gataataact aaatgcaata taatctgccg tgttagcttg caagcactgt
   102601 tcgtctccat ctaacattac tggtgcacag tcttcttcct tccatgtcct gtaaatataa
   102661 gctggataat gccctcggca catgacatcg gagaaaaacc atgaattgcg tttaaattgc
   102721 agtgaaccaa atacattctc tggatcacag tcatatgcat aagtcgctaa tgcagaaaag
   102781 ctacacataa tacccatctt agcatttgga tcgattttct ttaataattg agtagcacgg
   102841 gcgttcgcta gaaacatatg atgacaggct tgataaatca ctttttttgt tagtgtagca
   102901 atgggttcaa gtttatctct agcagggaat gtaaccaatc cagcagctgc ataaggcata
   102961 cgaaaagcat tattgatctc attaaaggtc atccaatatt tcactttccc ttggtagcgt
   103021 tcaaagacgg tctgcgcata aaattcaaaa aagtcgatta attttcgatt ttgccacccc
   103081 ccatactctc ctaccaatgc taagggggtt tcataatgac taagagtaat tactggctcg
   103141 atatcatatc gatttaatgt attgattagt ctgtcataaa atacgagacc agcctcattt
   103201 ggcttctgtt cgtctcctct tggaaatatt cgtgcccatg agatgcttgt tcgaaaagct
   103261 tttaaaccta actccttcag taaacgaata tcctcttcaa atcgatgata aaaatcaatc
   103321 gcttcatgag aaagataatg gagtgattcg tctaaagcaa tctcccaaat ctttttttct
   103381 tcattccact gaatactagg atgctggttc atgatcccga taagcgtatc tgtcacatta
   103441 ggtaatttgc cgtcttccaa ccatgcacct tcacattgat tagcagctac tgctccgccc
   103501 cataaaaaat tttctggaaa tatttcctga tccataacta tctctcctcg ctatcaacaa
   103561 tttcttactt gaagtatagc tcgattcatc aaaacaagat attctaacta tttcggcaga
   103621 agagaagaaa aaaattgaat gctactcttc atttttaata tttatatata acaaatacat
   103681 aagacgatcc ccgaaagaaa acactcgtta accatctaag caaacgattt attttacttc
   103741 caacacaaat gcttcataag gtcgtaaatc aactttgccg tctggtaact gtttcagagg
   103801 ataatttgac acaataaccc ttaaagcttc acgtggaata gtgaacgtct gcttttcact
   103861 ggacatatta caaataacga gccattgctg gtcttcatat atgcgagaat aggcaaagac
   103921 atgctcaggc gtcttttcca ctaattcata gtctccccag acgatgatgt catgttttct
   103981 acgcaaatcg atcaatttct tgtacatata aaaaacagaa tcttgatctg ctaacgcttc
   104041 ttctgcattg atttctttat aatttggatt gactcgaagc catggaattc cagtagtaaa
   104101 cccagcatgt tcacgggcgt tccattgcat aggcgtccta gcattgtctc ttcctttcgc
   104161 cttgattgat tccaagattt cctcttttgt aaatccagaa gaaatccttt cgttatacat
   104221 attgattgtc tcaatatctt ttgcttccgc gatatcatcg attgggcaat tcgtcatgcc
   104281 taactcttct ccttgataga tataaggggt gcctttcatc atatggagca agatagcaaa
   104341 catcttggca ctttcttttc gatacacatc gtcatttccc caacgagaaa caattcgcgg
   104401 aagatcgtga ttattccaaa ataaactatt ccatccttca tcacctaaag atgtttgcca
   104461 tttggataat acttttttca gttcagagat actcaagggt ttcaaatccc atttgtcttt
   104521 gccttcttgc tgatctaatc ctatgtgttc gaattggaag accatggata attcatttct
   104581 tttaggattg gaataaagtt tagcgatttc ggtagttgct ccccatgttt cgccaacagt
   104641 catcagattt ttgtcaccaa aagttgcttg attcatttcc tgaagatact catgcagttt
   104701 aggtccatta cttgtgattt ctttatccgg ttctttgcca atcatatcga tcacgtccat
   104761 acgaaagccc ccaatacctt tatcgatcca gaaattcatc atttgataaa tctcttggcg
   104821 aacctgttta tttttccaat tcaaatcagg ttgacgcttg ctatacaagt gcagaaaata
   104881 ttgccccgtt ttttcatcca actgccaagc agaaccactg aatattgagc gcaatctatt
   104941 aggctctttt ccattgaccg gatcacgcca aatataatag tcccgataag gattttcttt
   105001 atttttacgg gcctcaatga accacggatg ttcatcagaa gtatgattca ccaccagatc
   105061 catgatgata cggatatttc ttttctttgc ttcttcaatc agttcttcca tttcttccat
   105121 cgtaccgaat tctgccatga ttgcttgata attactgata tcatacccat tgtcatcatt
   105181 cggagactcg tatactggag aaagccaaat tgcatcaata cctaaatacg ccagataatc
   105241 caacctggaa ataatccccc gcaaatctcc aataccatct tgatttgaat cttgaaaact
   105301 tcttggatag atttgataaa caactgaatg gtgccaccat ttttgttcca tgattttcct
   105361 cctataaatg gatgtttcta ttttttgctt aatcatttat tttagtctct ctcactaaaa
   105421 attgtaacgc tttcaaatag ctattgcacc ttgttatcgg taacagaata aaacaaaaaa
   105481 acagctgagg aaattccctc aactgttttt tgaaaggatt gatttatgca gggaagaatg
   105541 ctgatttcac aacttcttta taaacggtgt tcactcagct gtcccttggt attagctcaa
   105601 aaaacggcaa aatataagaa actatttttt cgtttttttc tctaatactc aggccagaac
   105661 gctgatttca caacctcttt atttcacatt caatatccac atgaatccca caaatacaaa
   105721 gaacagacca tacatgattg gagatacttc ttttcctctt ttagctgcta acatggtaat
   105781 tggatagaag ataaaaccta atgcaatccc atctgaaata ctataagtca aaggcatgcc
   105841 gatcaagatc aagaatgaag ggatcgcaat ctctaagttt ccccattcga tttgtcgcaa
   105901 agattgtgcc atcaatactc ctaccataat caatgctggt gcagttactt gtgaagtaac
   105961 aactgatagt aatggagaaa agaacaagcc taacaagaag aaaatccctg tagtaatagc
   106021 tgtgatacct gaacgtcctc caacggcgat accagctgat gattctacaa atgcaccaac
   106081 aggagaagta ccaaataagg aacccgcaag catagctgtt gaatcagaag ctaaagcttt
   106141 ccctacacga ggcatcttgt tgtctttcat gaaacctgct tggtttgcta atccaactaa
   106201 agttcctgct gtatcaaaga aagtcacaag caagaatgtc agcactacga cccacatttg
   106261 aagagaattg atgtccccta catgttttaa tgcaactaaa aatgttggtt tcaaacttgg
   106321 tgctgcggca acaatttcag aaggcattgg aatcaaacct gtgaccagac ctaaaatcgt
   106381 tgtagctgcc atcccgatga agatgccacc tggtacacgc cgaacaagca agatagcagt
   106441 tacgactaat ccaaaaatcg tcaaccaagt agaaccaacg ttgagtgatc ctaatcctac
   106501 taatgtagat tcattcgaaa cgatgatccc accttcgctc agaccaagga aagcgataaa
   106561 tagaccgata ccgccagaaa tcgcatattt caaatctgct gggatcgcat caatgatcat
   106621 ttcccgcagc ttgaagattg tgatcaaaat aaaaatcaaa gaagcaacga atacgccggc
   106681 taatgctgtt tcccatggaa tccccattcc taaacaaaca gaataagcaa aaaaagcatt
   106741 gatcccaaga gcaggtgccg ttccaattgg ataacgggct aataccccca ttaaaacaca
   106801 gccgatcgca ctggctaatg cagtcgcagt aaacactgct ccttcatcca ttccagaagc
   106861 acctaataca gttggattta caaataagat ataagccatt gagataaatg ttgtaaatcc
   106921 tgccagtacc tcacgtttta ccgtggtgtt caatttttct atttcgaagt aggaaagtat
   106981 tttttccttc atcttccatc cccctaaatc cgaacattat aaataaagtc cgttaaaatt
   107041 tcgatttatt aataaaacaa cgtgttttat catatactaa aacaaaacat aagtaaacaa
   107101 aaaattcgga ttttaagcaa aatccgaacg ttccatctga ttaaatccct ttatctcaaa
   107161 gttcatgaac attcactttg gattacaaga atttctttat tgtgttaata aagtttcttc
   107221 attctagtct caaaaatcaa tagtgtgatt tgattttacc atttcgtttc tgttcttctt
   107281 tgatgaattc ttttgtatcg acaggattca gattatttag tccgccaaaa cctgtatcga
   107341 ccatttttcc ccagcctttt gtcttctttt ttcctgattt gagattcttt gctcgaagct
   107401 tctcactatg ttttgctcgc cgatacttca aataaccttc taatcttccc attagatcca
   107461 ctgtttttcc tcctttttat tcaatcagac gactcagctt ttcctataac aaaataattg
   107521 ccttcagggt cagaaaaatt gaaagtcaag atgccattgt tatctgtgat ttctcctggt
   107581 tcttccatgt tctcgtagat agtttcaaat tcatccgtaa aaaatactaa agaaggcggt
   107641 ggtcctaata cctctggtga aaacttctgc acaaatactt ttgggaatac gcctaattct
   107701 aattcttttg agatgctgag tacaatactc ttaaattctt ctggcaattc gattgtttca
   107761 gaaatttctg caccaatttt ttctacaaag aatcggcaaa tcatctctac gtcattgaca
   107821 taaagcatca cacgtgtttt ttgtatcatc atttgaccct tctttctatt tgattttctt
   107881 tcctgtctat aaactgattc cattatatca cgaaagcgca aacaccttgt gtttgatact
   107941 attcaagaaa aataaagcaa tagtttctag gattgctttc ctccacaaac tttttttaca
   108001 aaaaaaaaaa cggcaatgaa tgccgctctt cttatttcga ttcttttata attctgcttc
   108061 tgattcatct ttggttagtg tgtgtctaac actagttacg ccaaatgttt gatcgatttt
   108121 ttccttcaac gcttcgattg cctgtgcgcc acgtgccgct tgttcagcat tgatggattc
   108181 aatgaccagc accgctgctt gtgtttcttc cgtcagcatc gttctttggg cttcacgcca
   108241 gttgagacag cgacagatcg ctccttgttc atcatagtag atgatttctt ccggaagtgc
   108301 cggagcatcg gaatctgcac ctaaaggcag gaatgattcg ccaccttggg cttttcctaa
   108361 atgcagattt cctgcgatct tttcgatatc ttctccgccg caaggtacgc caaaagacaa
   108421 ggaaatacta ttatagatat ctacaagcgg attgattggg aaaaattccc gttcttgatt
   108481 tgcacgtttc agtaaagctt caatagaaga acgtgcacct tttttagtct tgaatgtggt
   108541 aaatgcctga cgccactgag caatgacttc gttttggctg aatgtttctt ctgtaaggta
   108601 atttcttgct tcttttgctg cctcattcaa taattgatga tacgtttctt cactttcttt
   108661 tgttacgtgg ttatcgatac catttacgga taagatttcg atggttgctt caggaaatac
   108721 ttcccagaaa ttggtatcca ctattacttt tttcatctgt tcacacctct tgattagaat
   108781 aattgcttga tgaatagata gtctgtttgg ggatcatctc ccatataaaa aacatgttcg
   108841 ctgtatttga taaatccttt tttacgataa aaagcgagcg caacatcgtt gtgttcccaa
   108901 acaccgagcc aaatggctgt tttttgcttt tcttttgctt tttcaatagc tgtatctagt
   108961 aaaaatgtac cgataccttg atgtttaaat ttttttcgta catagattcg ctcgatttct
   109021 aaaaaatgat cagccatttc ctcagattga ctcgttcctg tatttagttt caggtaaccc
   109081 gcaggctctt gatcgatact cactaggaaa aaatcggttt ctttatcttt tagctcttct
   109141 gtaagttttt ctagtgcata agcttgtgtc aagtaatcag ctaaatgctc cggtgaatta
   109201 tcttttccaa atgtatctgt aaatgtttcg atactaattt gttgtagtaa gtctacatct
   109261 gaaggcgtca tttttcgaat ttcgtattta ttcacggctt cttcctttca atagatcctt
   109321 ttattgcctt ttttgacaaa attccaatct tcgctaacat tcttgcatac tttatttaaa
   109381 agatattcca attgttttgc ttcttcgtca gaaagaccat ttaatgcgac tgcattggag
   109441 tagttgtttt ctcgaatgat gaaaggatag atttctgctc cttttttagt cggatagagt
   109501 ttcttgattt ttttattttc tttatcttcc aaacgttcga tcatcccatt ggattctaat
   109561 ttcttgattg ctcgggcagt cgttgtacga tctactttga tcatttctgc tagtttttct
   109621 tggatgattc caggattttc gcaaatacgt actaaataaa gatactgtcc tcttgttaaa
   109681 tcgacttctt tgaattcgat attgctaata gaatctagcg ctcgggcaat cattccgatg
   109741 tctcgaagga tttcagccat ttcatcccac ctttattttg tttgtaagac tagttcacct
   109801 ctttttgttg caaatgcaac tattttcaat aaaaaaatca agttcttttt taataactag
   109861 taaagtatat tcttttcttc ttttacgaaa aagctcaatc acaatagatc tggtttttgt
   109921 tttctaaaat aagtaactgt ttcttcgttg ttcgcttttc tgatagcttt ggcaactctt
   109981 ctatactaaa aaatcccatg ttggaagttt cattattctc aataaacttg gcctcttcac
   110041 cgtggatcgc acaagcaaaa acaagtttat aatactgaaa aagctgtgga atatcttttt
   110101 gtttattcgt atcaaaaact gctcgcaact gagtagtttc tactgttaat cctgtttctt
   110161 catagacttc tttacgcaca ttttcttcag gagacaatcc tatttcagca aatccaccag
   110221 gaagtgacca ttctttcgtc cgtttatctt cgattagtag gaccttgcca tcttttttga
   110281 tataggcacg aacatctact tttggtgttg gatgtccttc tccaatcgtt gtgagcgctt
   110341 ttatttcttc gaaagtttct tttcctattt cactgattag ttccaatgaa atcgtccgga
   110401 tctcctcaaa acgctcttta tcaaatacat cttttccata atatagacca gcttgagaaa
   110461 gtgcgagtag tcttttgtat tgagccaact tcttgttcat tctcttccct tcttttttag
   110521 caaatgtatg actatgtaat caagtataga agactggttt aattacggca aataaatata
   110581 atgaaatctg caataaataa aagaatgtta aaaaactcga gaacaaaaga cattcgactt
   110641 ctctggggct gtgaataaat ggcgttcaaa agcttgcatc tgcggtaata agccccacca
   110701 aacgaaaaat atgacgagct attcttgtct ggctgttctt attaattgag gcaggacagc
   110761 tttttcacaa cctccccact aaacggtgtt ctcctaccaa ctcctcggtc acaagtcaca
   110821 atattcatca aacatgagaa gctgtttttt tgaaattgct ccttgtgact cggagctgaa
   110881 cgacaggctc acgacctctc ggtaaacagc gttcaaaagc caatttttcg atattaagcc
   110941 atttctttgt tacttattgt cattgatttc tttttctaat ttatccaata gtggagtgta
   111001 atccacttga gtatagtctg ttacatcaaa ttcatatagt gttcctaact ggaatttgtc
   111061 atattttcgg tcggcgatga tctttttgaa tgcttctttc gtaatatgat tggtcccttt
   111121 cgttcgatct tccaatacgt caccatagtg ataatgatcc atgatatagc tcaaatgacg
   111181 atctgattca cgatcacgtt tgtaccgacg ttgccataac acttcaaagt ctgctgttag
   111241 gcgaatcgtg atcacctgat atccgtatct atctgctaat tcttggagtc gtgctttttg
   111301 cttatcacta aaaggatact cggacacaat cactttcttt cctgcttcca tatacaaatc
   111361 aagtgctttg taatagaaag gataaacttt cgtcctttct tgttccgccc gttcttccaa
   111421 attgttaaac ccgatggatt ctgcatagta ttccttgatt tcatcgagcg tgatggcata
   111481 catatctgga aatcgttccc gtagtttatt cataagatat gtttttcctg taccaggact
   111541 accagccaga agaatgaaat actttttcat ctcatttatt tcctaagtta attggacttt
   111601 ccaagttcat aaacagtcca atcttatgct tgacaatttc ttttactgct tcatttgctg
   111661 gaatcacatt atggcgaaga gacttgttga tttctgtttc actaaaggtt tctttagcta
   111721 ctttcgtcca gttgactaaa agctccgttc caacattgaa tttgcggatc ccgttattga
   111781 tcaattcagg ataatcttct tctttcacac ctgttcctcc atggataact agggggacat
   111841 caactactgc atcgatttct ttcagcaagg gaatgtttac ttctgttttt gatttgaatt
   111901 gtccatgatt cgtaccgata gcaatagcta atgcatccac gcctgtagct tctacaaatt
   111961 tcactgcgtc ttccggtctt gtatatacct tgtcattttc agcgacatgg attccttctt
   112021 ctgtaccgcc gattgttcca agttctcctt ctacggaaac accgtgcgca tgggcatatt
   112081 ctactactgc ttttgtcttc aggatatttt ctttgaaagg cagatgggac ccatcataca
   112141 tgacagaagt atatccgctg tcgattgctt ctttgatatc atcaaagtct cgggcgtggt
   112201 ctaagtgcaa gactgcatca accatttctt cttctgcaat agctgtcatt acattgacta
   112261 acacatgcat gccgatatat ttagcggtat cgacacttgt ttgaataatg atcggcgaac
   112321 ccatttcttt tgctgcgcct agcatagcag gaagcatttc taggttatgc gtattaaaag
   112381 ctccaactgt aaaattcaac tcttctgctg tttttgttac ttctttcaat gttgtataca
   112441 tcttttattg ccaccttatc tttttatttg tttcctttga tcgttacttg ttttgcaatt
   112501 tgtcgcatct catccatttt gcccatgtag taatcgatcc cttgatcatc accagcacga
   112561 gcagcatctg cacgcttctg gttatagagg ctcatcagtt ttttataccc atctccgatc
   112621 gtctgtttat tttccaaact cttttctaaa tattggatgg cttgatcgtt cacatacaat
   112681 tcagaaaatt taagtccaac ttgttcataa agtttcgcta atttatgctt atcttgggta
   112741 gtggaaatct cttgtttcaa ttgtgtaatc tctgattgaa tcttttcggt cgcttctggc
   112801 gatagggctt tttcttcttt tgccagaact tttttcggtt ctttttcttt tttcttaaaa
   112861 aatccaaaca tcattttccc tactttcaat taaaatgctt tcaaaactgg gcttaagatc
   112921 caggcatata agagtgctgc ggctactgta tctacatcgg ttgctgtagc attgatgaat
   112981 cccatcgaat taaagatcgt tactagcaaa gcgggcaata atgtaataaa gaaaccatga
   113041 gcaataccgc caatgatcgc tcctcggcgt ccgccaactg cgttgccaaa tatccctgct
   113101 gtccctccgg caaagaaatt ggttagcata ccaggtaaaa tcatcgctaa gccgaacatg
   113161 ggcaaagtaa acatggcaat aatcgtacca atcgttgtcg taatgaaacc taaaatgaca
   113221 gcatttgggc tataaggaaa gaaaactgga caatctaagg cagggatcgc atcaggaact
   113281 aatttcatag ctatccctcg aaatgccggc acgatttcac ctaacagtag acgtacacca
   113341 gctagcaata catacacacc cactacgaat tggatggctt gtaaaaaggc aaacatgata
   113401 tagttttgat ctcctgataa ttcagaagcg aatggttcgc ctgcaaataa aacagtgatg
   113461 atatatagcg ggaccatcac gaccatgaca gacaaataag tatcttgcag aaattcgaaa
   113521 tgtgtcggca acttgatatc ttcgatcgac tttttatttt cgcctttctc accaaaaagc
   113581 ttagcaacac cggcttcaaa taagtacccg atcgtacaaa aatgacctaa agcaatatca
   113641 tttgatccag tgattttacg aatgatcggt tgcgctactg ccggcatagc aatggcgaaa
   113701 caagctccga taaaatcacc gaccaagatc aatacgatcc ctcgcagacc ggcaaaatag
   113761 ccaaagactg tcgtcatcgt tgccatccat aaaattgctt gaccagttaa aaaaatgtac
   113821 ttccattttg tgaaacgagc caaaataata ttgaatacaa aaatggctaa gaacgtcagt
   113881 gcaatatctc tacctaaacc caaatcattc attgcttgac cattgataga ttcaatagaa
   113941 gggatgatcc cttgcatatg aaatccttca gtaaagattt tcccgaaata agttaaactt
   114001 ccaacgatga tgctcgaacc ggcactcaac acttgaaatc ctaggagtgt ctttaacgtg
   114061 ccagagatga cttgtcctgc tgatttcttc tgcagtagta gacccaacat agcaatcaat
   114121 gcaatggtga tcgatgcctg agtcaaaata ttttcgatga taaaattgat aacgcccatg
   114181 tttttaccct cttttctttt tgtatttaga taactccctt atcttgcaga actggggtga
   114241 ttttttcttc aatttcattt tttgaaacaa tatttttcaa atagatcatc gccgttttag
   114301 gatcaactgc gaacttttcg aactgcgaac gaaaattttc tgctgtgatg atcacatctg
   114361 gtttcatgga aactgcggaa gaaatatcac aatggtccag tttggcttct actcctaatt
   114421 tgttcaaaac atcctcagca gacatctgtg ctgcaaaact acttcctaaa cctgcaccgc
   114481 atacgaataa aatgttcaat ttgttcatct ttgttctccc ccgtatcatt tattatttct
   114541 caactactga aaaaagcagt tgtttgaaat cttcgatatt tgtgcattca atcaatcgat
   114601 ccaacttctc ttcgttgttg atcaattcaa ttagttcttt catgatgttc agatgcgagt
   114661 aggagtctac tgctgccaaa caaaaaataa tctttactgg atccatttca ggattaccga
   114721 aatcgattgg ttgctcaatc gtagctacgc tgactcctaa tttattgacc ccatcttctg
   114781 gtcgggcatg ggctagtgcc atgtgtttgc caatcacgat atacggtccg taatcattca
   114841 ctgcacgaat catcgcttcg acatagcgct cttcgacaat gttttcttta accaatggtc
   114901 tagcagctag ttcaatcgat tcctcccaag tagtggcttt ttctttgatc atgatattgc
   114961 tgtccgtcaa aatatctttt aacataggct ggatctccct tttgttgatt tctaaattgt
   115021 ttgtttcgaa taatttttct aacttgccat agatgattcg atctactcgg ccaccacttt
   115081 ctttcatgac atctattatt tgagtgaata actccgtcga ttcatgactg ttaggctcta
   115141 accgctgtag ttcttcattt cttttcaaaa agtcttctat aaccaagata ttcgtctcag
   115201 ttaaaatcgg atcgacaact aaaagcggct tatttcgata attcaattga aaggtgctga
   115261 aaaccagatt gacatccaat ttatctacta attcgatttc ttttgaactt aaaactgcag
   115321 taatctcgat ctgaggaaac ttttctttca gattctctgc taacagattt ccagtagcca
   115381 tcccatggtt acagacaacg actgatttat aaacataatt caagtctcgc ttgattacac
   115441 tggcgatcgt cgaaaagtgg atgacaagaa aagctatctc gtcctccagt atcttgccac
   115501 caattacttc ttcgatcgta ggaacaaaat gagtgactgc gcggtagatt gggaaataat
   115561 ttgttcggat gttttctttc aatggattca tgacttggat atgattcttg attcttacaa
   115621 tcagtgcagc catgtgctta tagagatttt cgaataaagc ttcttccttt agatggaaag
   115681 gtacgtgtgt ctcgttctct acaaattgga tcaattggat cgttagtaat tgagcttgta
   115741 cccactcgat tgaattggag atatctctag cattgaacgt ctcaatagtg aaacgaagat
   115801 aatttctttc tacttgcggg acattgtcca attgaaattc ctcgatcatg tggtcaataa
   115861 atgcagaaaa gctactgtct tttatttctg tatttttcca attaatggca gagataaatt
   115921 catgtttcct gattcgctgg atccagatca atgtaaaaag caggatttgt tttttataaa
   115981 tatcatcttc ttgtttcaac aacttattgg aatagatctc ctgtattttt ttgatttcca
   116041 ccaaaggaaa ataatggaga aagatttttt gagccggtgt taattgtgca tcttgattca
   116101 taaagaagtc ggtcattccc agattctgat tgataaaatc atagatcatc gtacggatag
   116161 atcgttctga acctttataa accagtcctt gctttccata actgacgatc tctatcccat
   116221 aactgaccag tgttgctcgt aaccgtctca tatcttcatc taatgtactt ttagagattt
   116281 gaaattcttc ttcttttttg tttagatgga tcgggattcg gctgtaagca acggctaaaa
   116341 ctagatcaaa aatacgttcg cgccgattca aaaagccgtc tttcacatct tttatttcag
   116401 tttctaatcg agcttgcttt tccttttcca gcttcaacaa aaaacctttg ttgcgaattg
   116461 tacggatctc cggaagcttt ttactgctca accagatatt cgcttcaaga acttcctgac
   116521 ggatcgtccg ctgactgaca ttgaactcac ttgctagatg ttttgctttt actggatatt
   116581 gggctgtcat gattctgtga agtatttcaa ttgttcttgt tttcatagaa atgatctcct
   116641 tctgatttca agtatatggt tccgcttaca taataaaaag tagatatttc tgccacttga
   116701 agtggaaaga aagtaagcaa agcaaacaaa aaataagcca tatgcttttt catctcctca
   116761 acgaaaaaga catacgccta ttattacaaa aattttgccc atctatacaa aaaagaggtt
   116821 gtgaaaaagc tgtcctgcat caagtaataa gaacaactaa actaaaatag tgcttcctat
   116881 ttttcgtttg gttgttctta ttatcgcaga tgcaagcttt taaacaccat ttagtggaga
   116941 ggttgtgaca gagatgttca gccttgagcg ataagaagcg attttgaaaa atcgcttccc
   117001 atattttaca aaatcgtgcc ttattgccga taggctatct ctggcacacc gtttattcag
   117061 aaaaaggagc tgcgacaagg cttttgtcac aactccgttc ataaatattt cctgtcaatc
   117121 cagcataatc ggctgaataa aatcggcttg ccatcttttt tctttctcag aaaaatcaaa
   117181 ataccatatc tgagaaaaat actgtcgttg tgtcttactt cctgagatca atcgcccatc
   117241 ttttcgatcg actgaataat cacagcatct gaaatcaatt cggatggcaa aactattttc
   117301 gtggatctgt cgataatttc ctacttcctg aatagttatt tttttagtat gatttcttac
   117361 accgtctgct ttgttttttt gcagaacttt ctgatgttcg gcaaacagct tgtctgtata
   117421 acagcttctg gctttttcag gagtttcttc ttcccaagcg gattggatct tcatgaatat
   117481 cttttggatt tccagaaact gtgctttctt ttctttagcc gttcctgaca tgcgggacaa
   117541 tatctccgct ttcagccttt tcttttgtct tttattcttg acgatagaaa aagcagaaac
   117601 ccctcctact gacaaaacag ctaatgcaag aaatcccgtt tgctcataac tagaaggacc
   117661 tgtacctgga ccataatacc cataagaatc tctgccgtaa gaacgactgc caaaataact
   117721 gcccccatat gaacgaccac caaatgaacc tctgcccgaa cttcgaccgc tagatgtacc
   117781 tccaccatga ccacccgcga cagcgaatcc ttgggtcggc agagcaaaca aacataggcc
   117841 cactaacaaa atgattgcta aataattgat ttttttcatt gtcttcctcg ttatctttta
   117901 ttacaaaaaa ctatttttat gatagccttg ctaaaaggaa gagtcaataa ccagatgcat
   117961 aaactgtttt tttagcaatt ttgtcttatt tagtcattga gtaacatcgg acaaatgtat
   118021 gtgtcggcag tccataattc ctctatcttc agcatgaaca agcttgcaga caagagatct
   118081 gcgcttcctc caggagagat ttggttttcc tgacaaaagt gcaacagtgc tgtaaatgga
   118141 cgatttggta aagcactttg actagcagca tgagcaagtt tttgcatttc cactaacgtt
   118201 ttctgatcac tgcgatgcaa tacgcatgtg tcatctagcg aactcatcaa aactaacaac
   118261 atatgcattt gtttctgtac atatgaatca ttatctagct ccttagctgc ttgaattgca
   118321 agcctgatat gcggataccc taatatcgct tcttcatatg caccatttac gccatatttt
   118381 tgcttcaccc tatgaccatg agtggttttt ttatgacgat attttgtatc aggaaaagca
   118441 gcaagcttgc tgacatcatc aagtattttc gataaagaaa aaggctgttc catactgatt
   118501 ttttgtgcaa tgacactgat caatagcccc attgcccaaa tcgctccttt atgggtattg
   118561 atgccatttg tagcaatcag cattgccttt tccgcttttc gcccaatctc agcaattctt
   118621 tctcttaact cctgatcaat agcgtgatgc catgctattt gagccatttc ttcaaaaaaa
   118681 ggagttagcg tcttagcaga cttaagaaat aaagcatagt ccatatcgga atgtgcaccc
   118741 gcatccagtg catccactaa tccaggtttt ggacttaatg ttacttctgc gatcaatgct
   118801 tcctctacca acgcagcgag ttgctgagtc actgcttttt ttcgttcgtc atttatcatg
   118861 acactcactc cttcttccta ctattacttg ctgaaacctt ttttgatagc tacccaaatg
   118921 atatgaagta accagcttaa agcaaatgca caacttgccg tcattagata agctacaaga
   118981 atcatgactc ctgaaggtaa ctgcagccaa ctatctttaa acaataataa cagtacttgg
   119041 aaaacaaata cattggctaa atacgtacga taagcataaa cagacaacca tttgaacaat
   119101 ggcaattttg gcgaatcgtt tacaatcatt ttggaagcgc ctatgaagac agcaaagatg
   119161 atgactaaac tgtataaact ttggatcgta ttcaagtaag gtgcattcgc aaagctcaag
   119221 tctcctggat gtgcgagcaa tgaacggaca gaaaagaacg cgataactaa ggcaacaggt
   119281 aagaaaagat aacgtactct gtccaaatat tgatagactt tttcgtgata aacaaatgcg
   119341 gctaccccat aaatcatgaa actagcaaca aaccgatcta ataagtacca gctgtcatga
   119401 taaggcccag tcaatacttg tgtttgatag aacagatacc atgcgacata taaaatcgtt
   119461 gaaccaatca atactggcca tacatatttt ttattagcaa atactttgta accgagccaa
   119521 acaaaaaacg gcatgaacaa ttggatctgc agcatcataa cggtatacca taaatgaggc
   119581 gctccatcac ctgtgacata tttcagtaaa aagcttgcag tatccgtata cggagtttgt
   119641 tgttggactg ctggaaatag ccaaagataa gccgtcgtcc atagaagata cggaacgact
   119701 agttcaaaaa acttttcttt caaaaattcc caataagaca aatgctgact tgtttttacc
   119761 atattataaa caattgcaaa aataaacatt ggtgctgtgt atttaacgat gacgtaaaag
   119821 gtaccaagaa aagctgtatt tgttgcgctg tggctgtttg ccaaagcaaa gctcaatatc
   119881 gtttgcatca taacagccgt tacagctgat actttctgga agtcacttac gttgattttg
   119941 atttttttgt tttcaaacat ctctttctct ctctttttct ttattaccaa agttctttgg
   120001 ttaatttagg tccttcgact gttttcaata gaattttttt ctctggctct ctcaaatact
   120061 cttttagtga aaaaccgcct tgccgagtca ctacttgggt atcgaattgc tcaaaaaaag
   120121 caggatgcga ttgaattacc tgaattggca attcaatcgg tgaatttgcg tacagcagca
   120181 aatcaaaatc actggtttct tttactgccg gaatcccagt cgataattca aatcctaagc
   120241 tgccgccgat tccccattta catcctgata atatgtttct agcagcatga aattgctgat
   120301 aaacaggata atccatgatt ttctcttgtc tatacgattc ttgttcgatg atgtcccacg
   120361 gatgaatgac ttgtttgacg gcatgttttg agatttctgt tgaccatctc tgattgcggg
   120421 caggtccacg taaaccaatc ggtagtattt ctgcgtgatc cgtcgacgca cgacgaactg
   120481 ttccgaacat cttttcagtt agaacgaccc attcaggcaa ggtgaaccct tctatttcat
   120541 gtttatcaaa aaggacaata tcatgtgctt gaatcatttt ttatgcatcc cattcttcgt
   120601 ccattttggc acggacttta tttgtttcga cacgtccgaa tgttttggct gtttcgtttg
   120661 tgtatcgatt tgtcagcatc gtgtcatttg tattgcggac atcttgaatg gcttcattga
   120721 ttgcttcgat gactttgctg acattttgtt ctgaagcagc ttggtcggtg atatcttcta
   120781 ggaaatgata gatcgctcct agttttgtat aattattgat atcgtaagcg atagctggaa
   120841 ctttttcagc agctgcttcg atttcagcaa ccgaacgttt tgtcacacgt gcagcacttt
   120901 ctttagacat cgcttggacg gtaatttctt tattgtttaa agcaatcaag cggcttgatt
   120961 gtaatccatg tgctaaaaat gcacctgaaa tagcatttcc tgcaatcaat ccaataactg
   121021 gatgtccagc ttgacggagt tttgcataag cagcagcact attagccaaa gccacatgga
   121081 taccgatcaa ttcttcgtta tagccgtatg cttggcttgg tacatcgatc acaacgatga
   121141 ttggccgttt cacttttttg tctttatctt cttcgtaaac gtgatccaaa atttgtccca
   121201 tgcggaaacc ttcaactaaa ccaacttcac cgtttcgtac acggtacatc gggtttttag
   121261 gatcaggtac gattgatgtc acgatggctt cttctatgaa tttacttgat ttaccataat
   121321 acacagtact aatagaagaa gttggatttt tcatgccagt tagtgccgca aaccaatcgt
   121381 aaccaacact tgctgcagct ggttcatttc cttctgctac ttctggtaag tcaattgatt
   121441 ttgcttgatg gttagcaatt gcttcattgt aatcgtcaat ggccattggt tttgaaagat
   121501 ctaaagaatc aagtaatgat aaataaaatg ctgagctttc actgcgatgc gtgtcttttc
   121561 gttcgtccat tgctgcgatg acagcagctt tgattgcttc tacactatca gtcactaatt
   121621 catcaatgat ttttgattct acccgttgac gagatcctaa tgtattccaa atcaagtctt
   121681 tgtcactaga atcaaattct cgaacgcctg cttcttgttc aataacttct ggtccattca
   121741 aaccgactct cgcttttttt gttgcgatta aataactcat taatgctgaa gtaatcgaca
   121801 taccgccaaa tgatcctaca cgtcctggaa tcaaaccgat gactggtaca tattgtttta
   121861 gagcaatgat tacatttccg atttctgaaa tagataacag tccgtagttt gcttcttgca
   121921 aacgaacacc acctgtatct agtacaatga ctggaaagat ctcatttcct tttttatttt
   121981 cttctaacac atgttcaagt gcagcaacga tttttgcacc ggaaacttca ccgataccgc
   122041 caccttggaa ttttccttcc atagcgatta ctactgcttg tttgccattg atcgtgccac
   122101 ggctgacaac gatcccgtca tcactttcag ggacgattcc ttgtgctggt aaacttggcg
   122161 cgatgatttg atcgaatgga tcaatcaatt cacgtccatt gtcaagtaga gcgttcactc
   122221 gttctctggc gtttaattct acaaaactat ttttcatctg aaagttcctc cattgcttgc
   122281 gtcaatcgta ggtacacaac tcctggtgta gcaccgaagt cattgatcac gatatctgct
   122341 gaaattggat aacgatcaaa aaatctcgtt aatacattgt tccatacttc gccgaagcca
   122401 tcgcttcctg tacaaatttt tacagtagat tctgtttttt ctgttggaaa catcaagatt
   122461 tccaaatctc ctgaaccgac cactcctaca tggattttct tattgatcgg ctgtttcgtt
   122521 ggatatttat aagctaattg ttccatggat ctctcccctt tttgtaaaac agagcataca
   122581 cgttctgctt attcgtcttt cttcttccat ctgggtaaat ggcgacaaaa ggtttttctc
   122641 gccaatttta tgaccaagtt ctgaatttca ttggtggttc atacaggcca tctgaccatt
   122701 cgatcaaatc atcgatggtt tgtgcagcta ataatgaacg tttcgcttca ctacgtttga
   122761 tgcctagatc ttctggtaat ttcacgatgc cggctgcacg caagctatct agtgattctt
   122821 tcgtgctagt cattccaaga ggtgtaacac cgccaattgc tgcaattgct gcttgtcgtt
   122881 cttcttttgt ttttgctttg tacaaataag caattccttc ttctgtcacg atatgtgtag
   122941 tatcttcgct ataaatcatc actggtgcat tggctaagcc tgcttgtttt tgaacagcta
   123001 gtgcatctaa ttcttcgaca aagactggtt ttttatttga accatatgtt tcaaccattt
   123061 gaacaactaa tttttggcct ttccctaatg gatcatcatt gtcgcgaagt gattgccatg
   123121 ctggtgtaga atgacgacga ccgccaggat tatgtcccat gttaggcgca ccgccaaaac
   123181 cagataaacg tccttttgtt acggtagaag agtttccttc gtaatctaat tgcaaggttg
   123241 aaccgataaa catatcgatg gcatattgtc ctgcagcttg tgataatgtt cggttactgc
   123301 gcatcgtgcc gtctttaccg acaaaaaaga catctgggcg agcagcaata tatttttcca
   123361 taccaacttc gccaccaaaa ctatggatgc tttcaaccca acctgattcg atggctggaa
   123421 tcatcgttgg atgtgggttc aatacccagt tcttcgcgat tttccctttt aaccctagtg
   123481 attcaccata agttggcagt aacaattcga tagctgctgt attgaatcca ataccgtgat
   123541 tcaaagattg tacgccgtgt tctgcgtaga ttcctttgat tgccatcatt gccattagaa
   123601 tttgcaattc tgtgatgttt tgaggatctc gtgtgaataa agcttctaat tgataaggtt
   123661 tatctgcttt cacgacaacg tctacccagt caccagggat atctacacgt ggtaaagaat
   123721 cgacaacttc gttgacttga acgatcacga taccatcttt gaaagctgca gcttcgatga
   123781 ttgttggtgt ttcttccgta ttgaaacctg tgtacaagtt gccgtcttta tctgctttat
   123841 ctgcagctac taaaacaaca tttggaatca aatcgatgaa taagcgtcca taaagttcca
   123901 aataagtatg gatatcacct aatttcattg tgccgtcttc aatcatttgg gcgacacgca
   123961 agctttgtgc accagcataa gagaaatcga tcttgcttgc gattcctttt tcaaaaatat
   124021 tcaaatgttc tggtcgtgag atactagaca tgatcaaatg cagatcattc actttttctg
   124081 catctacttt ttcaagactt tctgaaagaa aacttgcttg tttttgattg tcgccttcta
   124141 atacaacttt gtcgccggga gcaatcagtt tttccattac ttctacgatt ttttcagttt
   124201 ctacatactt gccattgagc aagttgctga ttttttccaa tcgctgcgct tttttttcgc
   124261 gtttagaagc ccagttgcgg tttggttttt ccataattag tcatctccat ttttgatata
   124321 gaaacgtggc gtcatcaata ccatgttggt ctagattgat cgtacggatc cctttatcta
   124381 caccaaattt tgtatgaatc agctttgtca aagtattgcc ggggggaaat tcaatcgtca
   124441 gatccattcc taattctttt gccaagtcca tcatttggtt ccactgcaca gggaaagcta
   124501 ggttttccaa caaatcttta cgaatctctt ctgcgtcctg agtggctctt ccatccgtat
   124561 tttttatata caaacatcta gcatcagata gatggacaga ctgcatatac ggcttgaatt
   124621 tcttgaccgt atcattcatc aagagacagt gagatggcac agggactttc agcagcttcg
   124681 ctgtttgcgc ttggtgccgt ttggcttctg ccaacgtaac ggataaacct tcgatactcc
   124741 cagataacgt atgttgcatc ggacaatttt catttgacag ataaactgga tggtcaggat
   124801 caaatgtttt tgctacaatt tcctcagctt cgcttctcgt cacacctact actacgccca
   124861 ttgcataacc gcttggataa gcttctttca ttaagactgc gcggtgatag actagttccg
   124921 ctgcattctc aaatctcaaa gatcgacaag caacagctgc acaaaaagca ccaatcgaat
   124981 gtcctgctgc aatatcaggc tgaataccgt ttttttccat ttcatctaaa taaaatactg
   125041 cttttgtcag taatgctagc tggataaaaa ccgtatcttg atagttttct tctttatcaa
   125101 ctaaccgata ccccgtcaca ttttctaaac gttccatgta catttcaggg atatccgcta
   125161 acatccctaa cttctgactg ccttgtccag gaaataagaa acctgtactc atgagcctcg
   125221 cctcctcagc acttactttt tccactgcta tcttagtcaa tttctgctat aataaaaaat
   125281 gccaaaaaaa gaaaaaacca taacaaaaag gtatggatgg gatggataat tatgaaattg
   125341 cttcatctgc agtattttaa aaaagtattc gaaacaaaaa atgttaccca agcagccaaa
   125401 gaattattta tttctcaacc tgccttgagc cgtgcgatca aacatttgga aaacgaatta
   125461 ggtgtccctt tgttttacca tagcggcaga aacattgaga cgaccgttta tgcagaagaa
   125521 ttttatccat atgcagtcaa gacattagac acattagaag aaggaatcaa attattgtct
   125581 tcggtcaatg agaagatcgt tacttccgtc atattgtatt tagaggtagc ctctgtttct
   125641 attccgaact tggtccgaat ttttatggaa aagcatcctg atatccaatt aacgatcatg
   125701 caacatcatt taccagatga tattaccgat cctgtactgt acatcacttc ggagatgaag
   125761 cctggcatga ccaatattcc tatcatgaaa gaacctgttt atgtcgccat tcctaagaaa
   125821 catcctcttg ctaaaaaaga acatctgcaa ttagaagata tccaacgcac ccccatcttg
   125881 atgctgtcaa agagcaacgc cttccgtcat acactggatg cagcacttga agcgaaaagt
   125941 atcgaattga cgatcagttc gacgacagat gatcctgcga cattacgttc tattgtcaag
   126001 caaggattag ctgttagctt tttcccaaaa gtttcttggt cttacgataa aaatgatcct
   126061 ttcgtcttgc gggaaatcaa agatttgccc ttgacacgaa caatttattt atcttctagc
   126121 ttcacagaag atcatccttt gatcaaaatg attgcaaaaa cgatgcggga attttattta
   126181 ggaaaataaa aaaaaaagag ctgggacaaa attcttgtcg cagctctttt ttcgaacaaa
   126241 cggtgttcca gaagtaattt cttagaaaat aagccgaaat ttcccaaaaa tttgagaagc
   126301 aattttcgta aattccttct tatttcttga agctaaacat ttctgtcaca acctcttctc
   126361 tattgtccta gacattcatt gcgttgattt aaaacttcca tcaatcaaat ctgctagttc
   126421 atctagcttt tctattttac gtagatcaat agagatccaa tgttctttat tcatgtgata
   126481 ggctggaaaa tacccctctt ttcctcgcaa aattccgcca agttcaggat cgaccttcaa
   126541 atcaagaata ttgatgatcc tatggtcact tgcatcatca tagatttttt cttctggaac
   126601 agacatcagg accccaaacc attttttgct tttttgatgt ctgaatacgc aataatcagg
   126661 aaatttttta aaaatatatt ctggagacaa attgtatgtt tcattgatgt gatcgattag
   126721 ttcttttttc gttagcatct gcttccatct ctttcttatt gattcgcttt attcaaagat
   126781 accacgtaag aatagaaaaa tgaatacaag tagttgctaa tcaaatactt cgatattttt
   126841 cttttttatc aactcttaaa tgttcaatcc gcctgtgttg gtcttgctac catctactat
   126901 taaaatgttt attattgttt gcccacctat tttttgattt tagtggtatc atttttcaag
   126961 ttcatgatga aattcttatc atcagtaaat gctccagaaa aataaacaat gattgaaaaa
   127021 tcagttgaaa cttgaccacc gtttattttc tccgtattct tagaatagaa gggagtctga
   127081 ttgatgtatt cactaatgaa aaaaatcatt accgaaaaag atattcgacg tcatgtttct
   127141 ttagtagaac aattgctgaa tcatacaaag ataaccgtaa atgaattagc tgaaatcata
   127201 gggacaaccg aacgaacgat tttttctgac cttcaatcta ttcgctctca gctgcccgaa
   127261 ggctgggaca tcatcagcga tcaagcagga atcagtttgc aaaaccagca aaatttatta
   127321 acaaatgacc tttgggagat ttttttcaaa caatcagtca gtgtcgaact gctgaaaaat
   127381 ctgcttttta caaaaaaagt tgctgtccct gattttctag ccgaccatgg gctttcttat
   127441 gggacattga aaagacatgt gactaaaatc aatcagcgtt tagcaagtta cgacttgcag
   127501 atcgatttga cgaaatatac agcttgtatt cttggaaaag agcgtgcgat tcgtactttt
   127561 tatcatcgat tgctgattcc tttcactcat aacaactatt ttttcgagga ttattcgatc
   127621 catgaatccc attattttca atttttaaga aacctcagtc aaactgaact agcggttgaa
   127681 acagaagaga ttttcggaac atgttggttc tttatcaata cgatccgtat aaaagcgaat
   127741 tgccgattag attcttctat ccataccaac agcacactct cctccctgta tgactctgca
   127801 ttgaaaaaat tgtatttaac ggaaggtatt tatcttaaag acactgagct ttcttttgct
   127861 tctttctgct ttctggaaag ttggaattac aacaataact atggacaaga aaccgctcgc
   127921 tgcctgcatc attctccatt tttagaggtc ctcgaaacgt ttgtagagga actagcttca
   127981 gagctgtctc ttgatcaact aaaaaaaaca tctctgactg ataacttggc tctcctcata
   128041 ttaaaatatc atgaatcgcc gatattgatt gaagcattgg accgtcaata ccatcgtttt
   128101 ttagaaacat atgatcagca atatgcacac ttgtatcaac agaaagagaa tttactgaac
   128161 gatctaaaaa aagaaataga aatcaatgaa ccaaattact ttctccaact cttgtctcta
   128221 ctgatccaac aaacgatttt ttctatcaaa ccgaatttgt tcaatgtcta ttttattttc
   128281 caaggagaac cttcatggaa ggcgttcttg cagcaggaat taaaagatta cttaggaaaa
   128341 cgtgtctgct tcttacctat cgaactaacc gatctttcca ctatttcttt tgaaaaaaca
   128401 gatatcttga tttccaattt ccctctagat tctctagata tccctattgt atacatttct
   128461 tctattccaa cgaaaaatga gctcaatcgt ttgactgaac tcactttcaa aactttttta
   128521 tagtaacggc tagcgactgt attctctagc tgttttttct tttttgcgaa acagtttgtt
   128581 catgatccct ttttctattt ctacaactaa gaatagaaga atcacatttg ctccaatcaa
   128641 taactgttgt gtcatcgtta aacttactgt accgatcagc tgctggccga ctggtagaaa
   128701 aataaccatc ccttgcaata aagcaaggat acctaatgaa agaaaaagcg ctttgttttg
   128761 caaaagacct tggttcaatg acggcttgga caactctctg caattgatca tgtaaacagc
   128821 ttgagctaag acgatatttt gcagaagaat ggtttgctgt aagctttgcc cttcaaactg
   128881 catagccaat aaataggcag gaaccatgat cagtagggag acatagatga tccgaaacaa
   128941 atgataacca gataggattc cttgctttgg atctcttggt gggcgcttca tgatttctgg
   129001 atctggcgac tcgaacccta gtgcataaga taaagtgatt gtcgttacca tattgaccca
   129061 taaaatctgt actggggaca aaggtagcgg gcgattcagc ataagtgccc aaatcaagat
   129121 caatccttga gctaatgcag ttggcaagaa gaaattgatg gttttttgca aattatccaa
   129181 aatccgccgg ccctctttta cggcttttgc aatcgtatgg aaattatcat ctcctaaaac
   129241 catatcagct gcctgtttgc ttacttcact acctttgatt cccatagcaa ttcctacatc
   129301 ggatcttttc aaagcaggtg catcatttac gccgtctccg gtcattccga cgatttctcc
   129361 atttttctgc aaagctttaa caattcgcag tttatgttct ggtgtcgttc gagcaaagac
   129421 atcgactatt ggcacttgct gaatcaactc ttcatcagac ataagatcca aatcgatccc
   129481 ttctaaaact ttggcagtat gttttaagcc aatttgttcc gcaatcgctt ttgctgtgtc
   129541 tttgtgatcc cctgtaatca ttttcactga gatccctgct tgttggcatt cctttacagc
   129601 tttgactgca ctttcttttg gcggatcgat caatccggcg atccctgcaa aagttaattg
   129661 ggttaaagtc tcatgcgtga gttcctgttt cgaatctact tttttataag caaatcctaa
   129721 aacacgctga ccttttctcg caaattctgc agctgtctga ctccatgctt cttgttctgc
   129781 agaagaaaga gttgatttag caaataatac ttctggtgca cctttgacgt aaatcaccgc
   129841 tcctttttcc tccgcatgca tcgttgccat atatttgtat tcagaactga acggaatctt
   129901 tgcttctatt tttttcaaag gtagattggc tgtttctgtg tgtcgaatca gcgcaacttc
   129961 tgtcggattg ccacttaaat tttctgtttt ctgttcttct tttgttttta attcctgaca
   130021 gtttttcata atggacaaca cgcaggcttc ttcttttgca gctacatcca caactgtcat
   130081 ttcatttttt gtcaatgttc ctgtcttatc tgaacagatc actgtcatag aacctaatgt
   130141 ttctaccgaa ggaagtcctt tgatgatcgc cttttctttt gccatttcat gtactccaac
   130201 ggatagaatc atggtcaaaa cagctggcaa tccttcgggt accattgaca ccaccaaagc
   130261 aatcgtagcc gaaagaagga tatgccaatc cataccatat cgaaatgtcg taaaaataac
   130321 taagaatagg ctcaaacaaa gaatgccttg aaaaatttgt ttgtttaatc ggttgatttt
   130381 tttaatcaga ggcgtcgttt gttgttcgac cgattgcaat gcttgattga ttttaccgat
   130441 ttctgtcgtg tttcctgttt ctacaacgac accgactgca gaaccagatt gtacaagcgt
   130501 tcctgaaaaa cccatatttt tctggtcgcc gatcgattct tcttctgtca aaacggcatg
   130561 acttttttca gatgcttctg attctcccgt caaaatcgat tcttccacta ataaatcatg
   130621 tgcttcgatt aatcggatat ctgctggaac gacatctccg gcacgtaaga caatgacatc
   130681 tccttttacc agttctttcg cagggatttt ttcttgcatc ccgtttgata gtactatcgc
   130741 ttcttgtccc atcagctgct tcaaaccatt caatgattct tccgcttttc tttcttgcca
   130801 gtaactaacg agtccattga cgatcactac gaataaaata atacttcctt caatatattc
   130861 actagaagca aatttcaaaa aagaggcaat gatcaacacg atcatcagca gatcagtaaa
   130921 atgctttgct atttttttcc atcgttttgt ctgctgcctt gcttttattt cattatatcc
   130981 ttgatcagtc aggcgtttct gtcgttcttc ttgcgacaag ccttctgttg atgtttgata
   131041 gtttttcaat acatcttcta ccgtcaatct gtaccagttc atcctatccc ctcctgttta
   131101 attgatactg ttattatacg cagggaagtt ttttcaggcg tatcgattat ttcagggggg
   131161 tctgaaataa ttcgttttgc aaaatgtatc tgggcctaac tgatatttct attgcttatt
   131221 cttttatata caaaatttaa gaatacaaac cagataacca ataaaaaagg aataaagcgt
   131281 gtcgtgcttt cgaataacaa gctgaaagca attgaagtaa aaaacaccaa caaagcaaga
   131341 tctttatatc tttgtgtagt gttccgtttc ttttctttaa taaattgaac atgtgcacac
   131401 aagatcgaag accacacaaa tagaaaacaa ctcgttgtca tgcctgccaa aagctgaaaa
   131461 aacaatcgac tatcagctac aaaaaaatgt agacaaagac cggcaaaaaa taacattcct
   131521 gtaattaaaa taccgtgtaa aggtacgcct ttcttagaaa gcgcacaaaa ccaatggggc
   131581 aaactttttt cttttgctgt ttgatataaa atcctgctag tactgtagac tgcactattt
   131641 gctgaggaca aagaagcaac caaaatcatt agattgacaa ttgctgctcc gccttggcaa
   131701 tggatcactt gcagcatagt cactaaagga ctttctttta aatctaaaca atgccatgga
   131761 acaacaaata aaatcgacaa aatcgttcct atatagaaaa agagaatacg ccaaggcaga
   131821 cagttgattg cttttttcaa attcttttgc ggatcacttg tctcgccaac ggttaagccg
   131881 atcatttcaa ttccagcaaa actgaataaa accataggaa atgagactac cattccagca
   131941 aagccaaacg gtagtaattc atcgatctgt ccaaaatttt ctttgattcc gatagactgg
   132001 gtatgaaaat ctgagacact caatcctata cccaataaga taaaaaggaa aatccccaag
   132061 atcttgatga ttgagaaaaa agattccaat tcaccaaacc acttgactgc aacaaggttg
   132121 actgccatta agatcattag tgcgctacct ccgcttatca aagctggtac atgtacaaac
   132181 cagaaatgga tatacaatcc tattgctgtt aattccgcaa gtccagctcc aagccagcaa
   132241 agccaataag tccaattgac aaaaaatgcc cactttttgc ctaaataata gtcaacgaaa
   132301 tcactgatag agttaaatgt actatttgct aaaaataaat cacccatggc ccgcatcaaa
   132361 ccataaatag ccaaaccgca tatcaaataa acgagaataa cagctggccc tgctgatgca
   132421 attgcctttg ctgaacctaa aaataatcct gttccaattg cgccacctaa tgcgattaac
   132481 tggatatttc gattagttag agtccgtttc attgccggtt tttccatcaa gttcaccttt
   132541 ttctttttca agcagcatgg cgacttcctg ttcccaagaa ggtttcttta ttttttcaat
   132601 acagagtggt actacaaaca aaatgacact gatggctgtg actgcaatta gattgatcca
   132661 tgttccagct ttcatcgtca gtccgacaga aaatccgatt gccgcaaata aaacaataac
   132721 gacagtccaa actccaagat tgctcttttt ctcttttttt ccaattctaa atggtcgatt
   132781 caactttgca tgtgtataac gcaatctcaa aactgcgatc cccatgatga catagacgat
   132841 acagtagata acagtagttg aatttacgag catcaaaaat gcttgattga cgccaggaat
   132901 cagcaaataa aaaagtgcaa agattgagat aatgacagac tgagtcaaaa taacggattt
   132961 ggatacgtca aattgattcg tcttccaaaa attgaatttt ggtggatacg caccttttct
   133021 agcactttct gtcactgtct ttgctggtcc tgaggcccaa gcagataatt ggactgctac
   133081 accaatgaag acaagtaaac taaacagatt cacaataaga tgtggcaaac caagaatttg
   133141 gcaataaatc gaaatagatt gcgcgatatt attcaattcc atttgtcctt ttggtacgac
   133201 atttgctaca actaaagcat tcaaaatatt gacgaaaaat ataaaaatta acgcggcaaa
   133261 tactccgcga atatacgttt taactggatt ttccaatcga gtgatataca cagaggacat
   133321 ttcgatacca gtaaaaataa acatgatcgg cgcaaaataa acaaatgagg atgcagtcgt
   133381 agtatctggt attaatttgt cccatgaaaa actgcctaat gttccggttg gtacgatccc
   133441 aactttgatc cacgcagcaa accctaataa gagcatcatc gtcaaaggca cgtacaatcc
   133501 taaccaaaca ccgacttttc cgccgatttt tgccatatca aatttcaaat tcaaaaaagt
   133561 gatgatccaa taaacgacta aaatgacaac taatgtaaat ttgctgttca aaccaagcgg
   133621 cacattatcg ataatattac caaacaacgg agcgagtgct gaagcgacca tcaccatccc
   133681 aggaaacatt tggacccata acagccatga gacaacgaac ccccattttt ttcctagagc
   133741 attcgatacc caaagttctg gaccaccttt ttggggaaac attccagcaa attcaccaga
   133801 gatcaatgag attggaaaag cgtacaataa tactgcaacc agcatgtaaa aaatcatcgt
   133861 ccagctcgtt gctgctacat ctggaatatt tcgtacactt gctacaaggg cgcaggtcat
   133921 tccgataaag gtcatggtcg tgatttgctt tgatgaacca gtatctttca tctttattcc
   133981 ttctttcaat agcgacatat gtttttgttt tcttttattt ttgttcaaga acagaaatga
   134041 caaggtttca tcgattcagt acaaaaccca gtatcaccga aacatccatt gaacgatctt
   134101 agtgaactgg gtttgataca tgaaacgaac gatccaactt atagaacgtt ttataaaaaa
   134161 gaatatcttg gcgaggaata tatgaaaaac agggggaaat acaattgttt tgatgaagca
   134221 aataattgtc tgttctccat atgtctcttg ttattctttc acacaaaaat cagttctatt
   134281 ggatgatttc gtttagtttc ttttccattg ctttggcgat tttttttgta taaaaattga
   134341 aaattcgatc atcattcaaa taaggagtca tgatagccgc acgtagcaga gtgattttct
   134401 gttctttttt ccattcttct ttcgttagac ccattctttc aacaaaacga atcggagaat
   134461 caccgtaatc ttcttgtgta aatgtagtat gagaagtaat aaaccgttca ccataaacat
   134521 cgccatccat ataagaagac cgatcgaaca ttttttcatt taattcattg atagcgttca
   134581 aatctgtaca gccttgttct ttgaataccc aattgaccat attaaaatca ggatgattca
   134641 atggatagac ttcgattgtt tttcctttaa cagtaaaagt cagatgatcg agaaattctc
   134701 tgaatctttg agctgcctcg attgaagccc caatcaattg accatatccg gtcacattca
   134761 atggcaatac acgatgtgct gtccagactg cggcggcggt tgctccagct tttgatcctt
   134821 ccaaaatata agctcctaac atatctggag cctttactga tttttcaaac acatatggcg
   134881 cgaaataaga aatgatattt ctcatatttt tatgtttgat tacgattcct ccagcagcat
   134941 aagggacata gcccatctta tgaggatcta tcgtgacaga atccgcttct gaaatagctc
   135001 tgaacccttc atatacctct ttgtcaatcg ttacgcagtg gtggaaaaca tgatgttctt
   135061 caaagaattc agctaaggaa gcatacggca caaattctcc tgcttcgttt agaaacagtg
   135121 aacgcgcata gccgccatat gcggcatcaa catgtaaata gaaatagatc ccttcatctt
   135181 ttaacctttc tcttaattgg acgattttat ctacactgtc tacttgacct tcttctgtcg
   135241 ttcctacgac agcaaccaca cctagaattg ggattttttg tccagctaat tcacgaattg
   135301 ttttttccaa agcattaata tccattcgat aatcctcttg aactgggata gcaaccatct
   135361 gatctaagcc gactccgcaa atatctaacg ccttcatcca agaatagtgt tttgtttgag
   135421 ggaccagcca tttccctaat ctttggatat tttttccgct acgggaagaa gctgctttga
   135481 cctcatccat ttcttcgtcc gtaaagcttt cggtcatttc caaaatttct tcaacagata
   135541 aattcaaaag ttcccactca gacatttttt tcactttttc aggcagcact tccttgacag
   135601 ctaaaggaat cgatttgatg caacgggcgt accataatcc ttcaagatta gcaatagaac
   135661 catctgctgc aatgtgtccc catccgtctg tcatattgaa taatgaagca aaatcctgtc
   135721 ctacttctgc ttccatttgc gaagttgcca tagaagattc caatgcaaca ttatttgggt
   135781 tccacagcat cgcatagttg taagctaata aagcaggcat caatgtttca gcattcattt
   135841 gtccccagta acggcctgct gaatgccatg ggatcgatcc tgcgcgtaat cgctgactga
   135901 cttcatccaa gacctctatc atatggtcgc gggtggctag ataatctgga gtgagcttat
   135961 ctccttcgct aattgcaggc atatctgaag gaatataatt ttctctccat ccaagatgtt
   136021 catctaccat cttgttcaac aacattttat aaactggtcc attttcagct ttgtcgccta
   136081 taaagacggc cttgatatcc atatctttca tttttcttcc ctccatattt tgttggtcaa
   136141 tgtcttgcag atacatgtgt ttatctgtaa cacctcttca ctatagcgcc aaaaatgaga
   136201 attttttttt tataacatca aatccacgta gatttttaca aacaaaaata aataaagtcg
   136261 gatttttctg ataattcaac gcaaaaaagc gaacaatttt tcaataaatc agtcttctaa
   136321 aatagataac ctaaaaaaag cgaacaaaca aataaaatga ctgtccttca ttcactaaac
   136381 atatttttat ttttttatat tgttaaaaat tcgcaattta ttttttaata gaattatctg
   136441 ttttccaaat tttataacat aaaaaacctt ttttaacggc atttatatgc tttttcagaa
   136501 attaactgat gatttcaaaa agaaaacatg tcataatatt tcccatattg tgcaaaaaaa
   136561 tacaaggcgg aggctctact atgattgaag aatatattga gaaaaatatt ttaagacagc
   136621 tgtttttatg tgggcaattc tatgtaaata aagaagtcaa tctagaaaag ctctccaatc
   136681 tcctgcatgt ttgcaaaacc actttactca atgatatcaa taacataaaa aaagaatttg
   136741 aagaacagat cgcttataca catcgggaaa aggaccgtta cactttatat ttttcagaac
   136801 atatacctcg atgcaagatc atgcagcaat tgtctcaaaa ttcgttgttt ttaaaaactt
   136861 gtctgcttta tttggaagaa gatgaacctg attatcttca attaactgaa tgtgaattca
   136921 tctctgtcag caaagcttat tcattaaaaa aacaagtatt agcttatttt aatgactgcg
   136981 ggatcgaaat cgaccgctac tcccctcgat tcactgaaat ggaaagacgt ctgctgcttc
   137041 ttaatgtgtc gtatcgttta ggcggtttta attcttggga gctacctgaa tcgttttttg
   137101 aacgtgccga tcgtttcatt gaatccgtaa cggaaaatag tggcagattt tatgataaag
   137161 aaaataaaga aatcttatcg attggttttg ctatcagttt cctacgccag caagtgtgtg
   137221 ctgtgacaat agattcaaaa tttatcgaag aaatcaaaaa acgtcctatt tacaattatg
   137281 tcgaatcagc atgggaaaac actgatttcc aaacctatta taaaaaagaa gaattcgcct
   137341 ttattttgac actattcaat ctttgtaatt atggtttcca ttcttatcag ttgattgcgg
   137401 aagactttca acagctacac caagtgttta ttgacaatac tcccgaaata aaagaactag
   137461 ttgctacctt tgaatctcac ttcaatcaag aattattcgg aaaccaaccg ttcgaacgtg
   137521 cgctgattca tctgatgcgt tcggcttggg ataactatca attattcatg ccagaaaaat
   137581 tttatctttt aaatgaggaa cagacaaatt tatataaaga agtccagaca attttttcca
   137641 gctggtccag ccagttacct tatgatctac ggttgaatcc taattgcatg cgggcttttg
   137701 tgatcgaatt gagcggaatt ctccgtctga caaaagaaca tctgactatc tatatcgtca
   137761 caaattcgga tgttcattat ctgatttatc gggaagcctt ggaagctgta actactttcg
   137821 attttcaagt tgcaccaaca atttattcaa gtatatctga tataaagaag tatgcgcagc
   137881 agtcctcaaa ccgggtatta tgtgaacgta cattatatac accagatgcg gtccaatatg
   137941 aaaatattat tcctatttcg atcaatacga tcgatcgagc tatcatttca gctgtgcaaa
   138001 acaaataagg ggctgtgaca aaaatcatgt cacagcctct tatttgttga agatgcccat
   138061 ttctgtaaca atctcttgat acacgtcagg ctcacaacct cacttatttt ggacatctac
   138121 gggtccgatc tctttattta aaaaataaga aatgatggtt cggataacta ccaacgccgc
   138181 tagttggaaa atatcctgca aggtaggttt gataatcgat tcgatgatcc cagctgaaac
   138241 aagaatttcc aaacttagaa gtatatagcc tcccaacatc tttttaatag cattgttctc
   138301 gctgactcgg tcgctttgca cttttgtatg gacaaataaa tatttcaaaa aatccttgat
   138361 tgatagacaa acaccccaaa ccaataaaca gatagcaaag atatcaagtc ccagtacaag
   138421 tttttcgaaa tatggaagaa gaaactgcat caactctgtc gtcatcctac ctctcctctt
   138481 ctttgttttt ctttgtcttc tatttcctga ttcaagaaat aagaaatgac tgttcgaatg
   138541 ataataataa gtgcaagctt caaaatatct gtccaagtcg gcttgataac tgactcgatg
   138601 atatcagcaa cgactagtac ttccaagctt aacaaaatat aacttgctag cagttttctt
   138661 gtatctgcat tacgagtatt acgttctgca tagtttttct tgacatgaga ccaatcaaaa
   138721 agtttgaata gaacaagaac gatcccgaca attaagatac cgatagaaca aatatttaaa
   138781 atagcaatga tccattctag aaattcaatt aaatttgagc gaaacatata cgctacctac
   138841 tttcttttaa tttgttccta ttcttttatt gtaaaagaaa gttaccttgt tcgtctattt
   138901 aaaagttgtt ctaatgataa cggttcgctt aaatttttct ttttcactct cccatttttc
   138961 tccctccatc cataaatcgt ggaagtatcc aaaacaacgt agcaagttaa aataaggctt
   139021 agtccgtcat cagcttttca aagaagcact gtctcggtgc tttttttgta cccaaatttc
   139081 taaaaataga accatacacc tcctcaaatc ttttcttctt acctacccta tttttattta
   139141 caggaaaatc agacacttct tcttttttgt caaaatttcc tttttcttct cgtcctatca
   139201 tttggcattc taataaaaac gaactatcct tggatataga aagagaaaac aaggaggcgt
   139261 ttttcatgag taaaaaatta atcaaagtcg gcatcggttt aggtttgctt gcccttggcg
   139321 ctgcatatct aggaaaaaag acaggactat tcgaagatga cagtcattta tatgatgaat
   139381 tcgaatcaat ctagcatcct atttagttga atcactacgg acatacttgg aagacattgg
   139441 aggaatcaca atgagaaaaa gtaaagcaat aatgattggt gccggtattg ccaatatggc
   139501 agcggctgtt tatttgattc aagaaggcaa atggaaaggg gatcagatca ccttttattc
   139561 attggatgat cacggttcaa atgatggtgc accgaccgac actgtagtgg attaatattg
   139621 gaataaaaac catccattag aaaaccaaaa aggctatatt gctcgaggcg gtcgcatgct
   139681 taattaccgt acctatgtag atttgatgga tctgttaagt cgaatacctt ctgttactga
   139741 gccagggatg actgctgaag aagatacgag agattttgat gcaaaacacc gaacctttga
   139801 caaagcacgt ttgatggaag gtggcaaagg aatcattgat ggcggaaaac tgggattcaa
   139861 taataaagac cgtattcttc tgactaaact gattgctatg cctgattcag aagaagaaaa
   139921 actagacaat atcactatcg aagaatattt caaagatgat ccacactttt ttgaaacaaa
   139981 cttctggttt atgtgggaaa caacatttgc tttcagaaca cgtagttctg ctcaagaatt
   140041 gcgtcgctat atgcatcaaa tgatttatga attcactcaa atcgaacatc tagtgggcgt
   140101 caatcgaaca cgttacaatc aatacgaaag tattatgctt cctttgatcg agtacttgaa
   140161 agaacaagga tgcaaaatca ttttgaaccg ccgtgtcact gactgggaat tcaaagaaac
   140221 accgatgcaa gatgaaatca ctgtgactgg tttgaaaatt accaatacac tgactcaaga
   140281 agaagaatac gttgtggtcg atgaagatac agcagttatt ttcactaatg ggtccattac
   140341 agattcagct actttaggag attacgaaac accagctgta gaaaatatgg attatggtgc
   140401 agcttctagt ctctggaaaa aagccagtga acgtttctac aacttgggaa atcctgacaa
   140461 attctttgct gatcgagatg caagcgaatg ggtcagcttt accctgacga cgaaaaacca
   140521 tttgttgttg aatgaaatca cccgtatcac gactcaagaa ccaggaaatg ccttgaattc
   140581 atttatttca accacaccga tcacgccgtt aggccaaaaa gatgtcaata tgtctatcgt
   140641 cgtgcatcat caaccgcatt ttacgtctca gaaaccaaat gaaacagtta tttggggtta
   140701 tttcctttat ccaagacgac gtggcgaatt tgtggataaa cagtatatta aaatgaatgg
   140761 aaaagaaatg ctagaagaac tgattggaca actttcaaaa gtagatcctg gaccagtgaa
   140821 tattcgtgaa aaagaaacag aaattttcga cagcgtaata aataatatcc ctgtctatat
   140881 gccttatgct tccgcgttgt tcaataatcg tgccaaaagc gatcgaccaa aagtcattcc
   140941 taaacattcg accaatctgg cctttacagg agaatttgtc gagcagcctt atcagatgat
   141001 ctttactgaa caaagtgctg tacgttctgg agaaatcgct gctttccatt ttgcgggtat
   141061 tcctatgtcc cgtcttgtca aaacaccgcg ttacgacaaa gatattccta ctctagctcg
   141121 tgccgcaaaa aaaatgtttg aataatcaag aggttgtgaa aaagctgccc tgcatcaagt
   141181 aataagaaca accaggctaa aacagcttct tatgtttttg atttggttgg acttattacc
   141241 gcagatgcaa gcttttgaac accgtttacc aagaggttgt gaaaaagctg ccctgcatca
   141301 agtaataaga acacccaagc taaaactgct tcttatgttt ttgacttggt tggacttatt
   141361 accgcagatg caagcttttg aacaccattt accaagaggt tatgaaaaag ctgccctgca
   141421 tcaagtaata agagcagcca agctaaaaca gcttcttatg tttttgactt ggttagactt
   141481 attaccgcag atgcaagctt ttgaacaccg tttaccaaga ggttatgaaa aaggcgttta
   141541 gtttcgagta tgaagaaaaa ttttgtgaaa atggttcctc acgtttttgc ataaatttga
   141601 cttaataccg agaaactgat cccttctgtc ataacctctt tttatttatg tctgtttctt
   141661 tttgaaaaca actatttttt caacgtttac tctcttgcca atccaacatc atctaacgga
   141721 tacaactatt tcgatgatta ccattacact aaaaaatcgg aaacacacct ctccgaacac
   141781 aaatacataa gactatagaa tgtttcattt aagaaaaaaa gcgtttcatt atcaaaaagg
   141841 taagatctcc tttaaaatga aattatctgt agtactaata atgcagacaa ttttatgaat
   141901 ctgaaaggag catctccaat gaaagcagtc acttggcaag gaaaacagaa aatggaaatc
   141961 agaaacgtag atgatccaaa aatattagaa ccaacagatg caatcatccg tatcacagca
   142021 acagccattt gcggctccga tctgcatctt taccatcatg gtgaagcagt tttggaaaaa
   142081 gggtatgttg taggacacga accaatggga atcgttgaag aagtgggatc tcaagttcaa
   142141 acattgaaaa aagggcaacg tgtggttatc ccttttaata ttagttgtgg tcattgtcat
   142201 ttctgcctga atcacatgga aagccaatgt gatgaatcaa atccagatca gttatatggc
   142261 gggcttttcg gatttggcaa gttgaacggt aatcattggg gtggtcaagc ggaatatcta
   142321 agagttcctt atgcagactc tacttcattt gttgtaccag ataatgatct tcctgatgaa
   142381 aaagttttat ttctatcaga tattttgccc acagcttatt ggagcgttga aaacgcagga
   142441 gtaaaaaaag gcgatacagt tgtgattcta ggttctggtc cagtcggtct attcgctcaa
   142501 aaattcgctg ttatggctgg agcagagcgc gtaatcgcag tagatccagt acagcaccgt
   142561 ctagataaag cggctaatta caatggggtt gaaacttatt tcttagaaga cacggcacaa
   142621 gctggaacag aattgtatga actggctaaa ggtggcgcag atgtcattat cgattgtgta
   142681 ggaatggacg gattagagcc tgtcaaagaa aaagcgaaaa atttagtaag cttacaaagc
   142741 ggcacaatct ctccattaca gatggcatcg caagctgtca aaaaatttgg aacagtccaa
   142801 gtaactggtg tttatatgac tccagcttct tcttacccgc tgcaagaatt ttttatgcgg
   142861 gatatcgctg tcaagcatgg acaggcacca attatccatc taatgccaaa aatttacgca
   142921 atgattgcag aaggactatt cgatcctaca caaatcatta ctcattcgct gccactatca
   142981 gaagcagcac aagcatatga gatctttgac aaaaaagaag ataaaaatat aaaagttgtt
   143041 ttgaaacctt gaattcagta aaaaatacag gtgattttct ttatgcccaa aatcaaacga
   143101 aatacccatg agatcgaaat aggaaaagaa gaagatatcg aaatacgagg acgtcgcttc
   143161 cgcttctatt tccaaaatcg ttacacattg atctcactgg ctgtcgattt attaaccggg
   143221 attttctata tttttggaag ccttgcttcc ttaactaaaa tccccgatcg atatggcacc
   143281 tatttttatt tggctggtgc tattttcttg acgattcgtc ctattctcag aatcgtaagg
   143341 aacattttta tttacgacga aaaaaaagca atgaagagaa caagcaaaaa aaaagaggca
   143401 tgagaatttt tcaaatctca tgcctctttt ttcaccctat cgtatcactt tgatacagac
   143461 gagcggtcgt cccactttct tccttgacca ttgtcaaaaa tgtccactcg tatcgttcat
   143521 aaaacgtggt atgatctgta attaagtaaa gtttttcgta cccaagttga tgcatttctt
   143581 ttctgatttc cgctaatatc cgcttggcta tcccctgctt acgcttttcc ggttcaacaa
   143641 acagggcaca aagatttggt gtcagatcag ggcggttatg gaagtcgttt tcaatgacgc
   143701 ccgctcctcc gacgatggtt tctttttcat ctaagaccac ataccattga ggaatacttt
   143761 ccttattagc gattccagta cgaatacttt cctcatacac aacagcagga actccccatt
   143821 ttgatgaaaa ccaattcgcg ctttgtttta ctaattctgg gtgttctctt aatttgatcc
   143881 agttatatgt aaccaatgtt taaacctccg actaaaataa aacgtttaca aaaattatac
   143941 aagtctttat gaaaattagc aatgacaaca atagtgatgt aaaaaaaaaa acggaaaaca
   144001 atcacttgtt ctccgttttt tgattgatca agcatctaaa gcttcttttc ttctttcttg
   144061 gatcgtagct accttgacga acggtagata gatcaaaata gaaagaacca aattgacagc
   144121 ggctagtaca ccacctgcaa tactttttgt tgccaataca ccgccaataa ttggtggagt
   144181 tacccatgga ggcataacgg tagctgctgg cactaaacct gtagaagtcg caaagtaagc
   144241 aacactaact aagaccattg gtgtcaaaat aaatggaatg aacatgatcg ggttcaacac
   144301 gataggtaac ccaaacatcg ttggttcatt aatattgaag gacacctggc gcaatcgaca
   144361 agtttgttac aaccatatat ggtttgtttt tacgtcctac taaataaata gctaacagta
   144421 aacctaaagt tgcacctgtt cctcctaagt tgacaaagct gtcaaagaaa ggtttgttca
   144481 cgataaacgg tgcgctatgc ccagctgcga ttgcattaac gtttgcttca atggctggcg
   144541 cattgattgt ttgcatcaaa ggatcgacca tattcgctcc gtgtaaacca aagaaccata
   144601 agaatggtgt gataaatgca agcagtaagg cagatggata agagtttgca agtcccataa
   144661 atggttcttg gaccactgta tagaaagaac ctacgatatc atcaacaccg aatgcagcaa
   144721 aaattgcagc aactaaagca aacgcagaga tagtgatcat tgctggtagt aatgaagcaa
   144781 atgcttttgc aactgccggt ggcacaccat caggcatttt gatgatcaat ttttcatttc
   144841 cgcttaaacg tacaaagatt tctgttgaaa taatcccaac aataatagca ataaacaaac
   144901 cgtttgagct catacctaat gctccgccta aagcgaagaa agagcctaaa gaaatcacac
   144961 ctgcggaaac accgtctttt cggtagccgt tagctaaatg ataagcaagc aagaaagcaa
   145021 tcaagacaga aagaatggca aatgtaccgt tccaagcagc agccccgaat cctttccatg
   145081 attcaccacc aaaaattgag ttcatcaatt cttggaaccc gggaatcggt aagttattga
   145141 tcattactgc taatgctcct aagatcatta acggcatact caccataaat gagtcccgaa
   145201 tcgcaactaa atgccgttgt gcaccaattt ttgatgctac aggtataaaa tgtttctcca
   145261 taaatgcaac aaatttatcc ataaatcttc cctcttttct ttactgtaga ttacgcgttc
   145321 aatcgacgat acagatcaat gatctctttt gctaaatctg taaaagctat agatgtcatc
   145381 agatgatctt gactgtggac cgtcaaaagc gtgacttcaa cgtgatttcc ttgtgcttct
   145441 tgtgtcagca tctctgtttg agagtgatgt gcttggacta aagattcctc tgcatctttg
   145501 attttttcat ctgctaaagt gaaatcacct tttttcgcag cagcaatcgc ttccattgca
   145561 tcgctttttg catttccgcc aaacatgatc agacccatga tggcttctag atttttttga
   145621 tcttccattt attgtatcct ccgataattt ttattatttg tttattagtt tttctgcttg
   145681 gtcgagtact ttttcaccat tcatcatgcc atagtcagcc atattgatta catctaaagg
   145741 aatgccttta ggtgctagct tttcagcaaa ttgattttgc ataaagcgta cttgcggtcc
   145801 taaaagtaaa acgtctacat ttttagattc tagttgatta tccgcatctg aagcagatac
   145861 agcaaagatg tctgcttcca ttccttttgc ttctgctgcc ttttgcattt ttgtgactag
   145921 gagacttgta ctcattccag ctgaacatac aagcatgatt gttttctttt ccattttaaa
   145981 cacgttcctt tctatactta cacttgtata taagcaagta gcgtgccaac tttaaaagcg
   146041 ctttaaaaag ttgatatcat cacatttaag gtctatacca agttgcatac acactaaaaa
   146101 agaaagcgca cactaaacac acaaattaat ttttattacc ttttttcttt taacgtgcac
   146161 aaaaaaagtt gtgacacaaa acttgtcaca acttttttca aataaacggt attcaaaagc
   146221 ttgcatctgc ggtaataagt ccaaccaagt taaaaacata agatgttgtt tttactttgc
   146281 tattcttatt acttgatgca ggacagcttt ttcacaacct ctcaataaac ggtgttcaat
   146341 cagctgaccc tgggtattag ctcaaaacgc tggattcaca acctctttta tttcaaataa
   146401 ccagtaaata caatgaacat ctacaaaaaa cttctattta tttatagatt tcgtcaggca
   146461 aatccaattc tctcttatca atcaaagtct gataccacga agcagatttt ttcaatgttc
   146521 tgcttcgttc atcgttcaat tcgattcgaa ctaatccata tcgattctta aatgcattca
   146581 ttggtgacac acagtcagtg aatgcccata acatatagcc ttcgcaattt gcgccttctt
   146641 ctgttgcttt gatcaagtaa tgcaaatgct gtccgataaa ttcgatacgg taatcatctt
   146701 gcacgattcc tttctcatcc atatactgtt cttcatattc tcttcccata ccgttttctg
   146761 ttatcagcca agggatatta tgataatttt cttttagata catggctata tcatacatga
   146821 ttttcggata gatttcccat cccctggaat tattcatttt cttcccaggt aaatcaaaga
   146881 cttcataata tcgttcagga tggaaaggtg tctcttcatt ccattgataa cgaggggcgc
   146941 gaacgcgttt aggataatat tgattgattc caaggaaatc tactgtatga tgctgaatcg
   147001 tttctaaatc ctctgttgca ggatcgaaat aaatcgattg tttttgacac aactccagga
   147061 actcttctgt gtagtatcct tttaccatcg gatcaaaaaa tactcgatta taaaacaaat
   147121 catacatata agcagctttt tggtcttctg gagaattgga tcgagcatag accatttcag
   147181 gatttaaaat acagccaatc cttccaccat aatttccgct gcggtaaatc tctactgctt
   147241 tagccgttgc taaaacttta tgataattcc acatcatcca cttttttgtg ttttgttcat
   147301 gcggccagcg aacagcatcc aaatagcaac gcgtttgggg aacgattggt tcgttgaatg
   147361 taaaccagtt ttttacccta tcaccgtaac gatcaaaggc aatttgagca tacttagcat
   147421 aaaaatcaac tacttttctt gaagaccagc catcatattt ttccaaaaga aaagctggga
   147481 cttcataatg ttccaaacaa atcatcggtt ctacgtctgc ttcgatcaaa gagtcgatca
   147541 tttcacttat atgctgagca tattcttcat ctactataca gttctcataa tcagtaaaaa
   147601 aacgagccca attgatagaa gtccgataat gtgtcagatg gatggatttc atcagatcca
   147661 catcctgctg gtattgttcc ataaaattag ttgctacggc tgggccatac ccattatgcc
   147721 aaacaaaatg ttcattttta taccagctat ctataaacga atcctgtcct tctttttttc
   147781 ctttccaacc ttccgtttgc caagcagaag atgcagcacc aagaataaaa ttttttggaa
   147841 tagtaatttt catgatttcc tcctgttttt tagatcccat cattttccac acgatttgct
   147901 acttttacaa atggcagata gatcaaaata gaaacaataa tacaaacaag ttgcgtaata
   147961 actgcaccga tatttcctgc tgttgccaga taagcattga cgatcggcgg cattggccaa
   148021 gggaccatta caactgcttt cgccgcaaat cctaaagcgg ttgcaaaata accaatcgtt
   148081 ccagtgataa gaggcgttaa gataaacgga atagctaaaa ttggattcag catgatcggc
   148141 ataccaaaaa taactggttc attgatgttg aagatcccag gagcaaggga taacttggtg
   148201 atttgtttca tatcttcccg ttttccaact aacaatactg caatcagtaa accgatcgtg
   148261 actccagacc cgcccatact catatacata tcccaaaatg gcatagtaat aatgttcggt
   148321 acttcttttc cagcttcaaa agcttccgta tttacagcaa ttgccgctaa aagcaacggt
   148381 tcccgtatcg gcttcaccat ttgatttcca tggataccaa tcacccaaaa gacttgcgca
   148441 ataaacatca atagcaaaat acccggtaac ccttgtacga caccttctaa tgggcgttgt
   148501 acgacattgt aaatgatatc ataaaggtac attcctgtaa gttctttgat gataaatccc
   148561 gcagccgcga tacccgatac agtcagaatc gtcgggaata aagcagaaaa actagcagaa
   148621 acattcgttg gcacggtatc aggcattctc agctgtagtt tcttctgttt cctcaaccag
   148681 caataaagtt caatagaaag gatggagacc aacattccca aaaataaccc tttcgtatct
   148741 gtatattgtt tagccaatac gttttctact ataacagtct gattttcatt cactaattca
   148801 taaacagttg gattaacaga taaataagac atcactgcga tgataccagg gaatacacca
   148861 tccactttat tcagcttggc taattcgatc cctatcagaa aaacagcata gatggtcaag
   148921 aaacttagtg tgacatagct gatggcagat gcgataggct ttaattcttc taaaaaacgc
   148981 aagaaactta tctgtgctaa gccattttcc gagtcaaaga ccattgctga aaacaatgtg
   149041 ccaaaagcac ccgtaataat taccggaatc aatgcagcaa atgcgttttt tatcaccatg
   149101 atatacctta aattattgat tctcgttgcc acgttcccta aaacattggc taatttatcc
   149161 ataaaactca ttccagatcc cctcattcct gcttcttctc cttgacgtca tctctttttg
   149221 tctattagtc agcgcttaca tttcgatgaa cagaaactat ttactcctct tttttaccaa
   149281 atataaaaca aaaattcatc tgatgtattt atcataaaat acatcagatg aactgtcaat
   149341 tagtttcttt ttctcctatt attttctgta attctctccg atttattgcc atatggacag
   149401 tcattgcatc aaacgcagca agtgcattcc gcctttcgat ggcctgaacg atctctgtat
   149461 gaatatcgat cgtctcgatt ttcagatgct ggatatcata atttttatta aacaaagcaa
   149521 ttgattcatt aatgattggg ataatatgca gcaaggctac gtttccgcta gcttctgcaa
   149581 tcatcgtatg aaaatcgatg tctaattgaa catgttcttg tgtgccttct cgaaaagaag
   149641 tttcaatctt ttgcgttaat tttttcattt ggacgatttg attcttcgtt gcatattccg
   149701 ctgccaaacc tgccatctta ggctccaata aatatctcag ttcaaataag tctcgtatca
   149761 tccgatcctg atcttcaatc aaagaaaaac cgagtgggtc attggcaatc cctcgcttat
   149821 cactgacaaa tgtccccgct ccttgccgaa cttcaaggat attcctggaa gctagagccc
   149881 gcacagcttc tcgcaccgtg cttcgcccca cctctaaata atcggacaat tcatattcat
   149941 tcggcagttt atctcctact tgcaactgca tttcctttaa atatctaagg atcttgtcag
   150001 tagttacttc tactagggtt ttattttctt ccaaaccaca tacctccttt tcatctgatg
   150061 tattttttcg taattattat aacacgtttg aatcatctga tgattttttg tatacaaaat
   150121 tgattaatcc gttcatagac atacaaacga agaagatatt taccataaaa aagactagga
   150181 taaaattcac tcctagcctt cgatcatttt tattttgaac gacaaaaaat atgatgttca
   150241 ataacagacg atcttcattc gattcttgat gtcatctttt gtttttttta atatatggat
   150301 aaaaagtttg attacatcgt ttctattcta gaatttggtc gattctcaat tcttcttctg
   150361 gtgagaaatc taaattatcc atcattcgaa cactttcttg taactgactt aaccgacttg
   150421 ctccgaccag tacacttgta acagattttt gtcgcaaatt ccatgcaagg gccatttgcg
   150481 ctaatgattg tcctcgtgat acggcgattg tttgcagtgc tttgattttt tccagagttg
   150541 atccaacttg ttcttctgaa aggaatggta tttccttacg atgtgctcta gaatcttcag
   150601 gaataccatg tagataacga tttgtcagca acccttgagc aagcggactg aacgtgattg
   150661 cccctagccc ttcttcttct aatactggag atagatcgtc ttctagtagt gcacgagaaa
   150721 acatattgta gcgcatctga tgaataatga acggtgcttc ctttcttttt aaaatttcag
   150781 tcattttttt tgtatcttct ccattatagt tggatatacc aatatataat gcttttcctt
   150841 gtcttacaag ttgcatcaaa gcttctgctg tttcttccaa aggtgtatca gggtctgggc
   150901 gatgatgata gaagatgtca acataatcta gccccattct ttggagactt tggtcacaac
   150961 ttgaaatgat ggatttacga gagccccatt ccccatatgg cccttcccac atatgataac
   151021 ctgctttgct agaaataatc agttcatcac ggtaggcttg aaaatcttct ctaaaaatac
   151081 gcccaaagtt tttctctgca gctccagcag ggcctccata attattcgca aggtcgaaat
   151141 gggtaattcc catgtcgaat gcgcctctta aaatctctct ttgattatgg ataggatcat
   151201 aatcaccaaa attttgccat aatccgagag ataaaatcgg taatttcaaa cctgaatgac
   151261 cggatttacg atattccatt ttttcataac gtgcactatc tgcaatatac aatttttctc
   151321 ctcctcatca aatcttttta aaacgctttc ttttttctat ttttagttta ctacatttta
   151381 aagaaaagga gttaatcaaa atgatttttt cgtatatttt tttgccattt gttttttact
   151441 cgttgataga tcagaaattg attacgtgct tgctggattt ttttataacg tttcggttgt
   151501 tttttgtaaa attgctgatg atagttttct gctggccaaa acgtaccggc tggttcgatt
   151561 tttgtgacga ttggttggtg gaaagttcct gaactgtcta gtttctgttt tgattgttcc
   151621 gctaattctt tttgtcgttc gccttgataa aaaatcactg gacgatattg cttccctcta
   151681 tcttgaaatt gtccaaatgt atctgtggga tcagtaattt gccaatagat tgtcagcaac
   151741 tcgctataac ttatttctct tgtgtcataa atgatctcca cagcttccac atgacctgtg
   151801 taaccaccac ttacttgatc ataatttggt ttttcaacat gtccgcccgt gtatcctgac
   151861 aaaacagata ggatcccttt tttcgattca aacggctcga ccatacacca gaaacatccc
   151921 cctgcaaata ctgcacgttc ttgatagtca gcatcttgca tggcatgctt ggaaaagtca
   151981 tatttttgct ccttatcaaa tccttccgta atcaataaat aaaagtccat tacatcaggc
   152041 gtcagattca ttcggatagc taatggacgt agtgttgctt ctagttttga taactgttct
   152101 ttaacggata tattttctct tatgtcattc tttgtctgaa tcaatacttt tcgttcccaa
   152161 tctcgtgtat tcggattcaa aatcagatta taaagtgttt gaatgaatat ttgttcctca
   152221 tccatagatt ctcctccttt ccgaagaaga caagctagtg actttagctg taatttatca
   152281 taaagtgagg aaataagcga ttacttcatc cccctacaga tttttcgtat aaaaaagaga
   152341 gaatccttat cgacagattc tcctttttaa tcaatttatt ttataaatga aaagttaatt
   152401 taccttttat ggaaaactat tttaaaaaat aaacataaat atgcagttaa tgtaacaaga
   152461 taagaaataa tagtcgttac tgtataactt gtgcttactt taatatcagc aactcctttg
   152521 actccgctta tttgtaccaa tccattagca ttcacctgct cctttacagg ttgatgattt
   152581 atttctacat tcgttcctaa ataagcatat acaggaagtg tgattacttg gctcttctca
   152641 ttagttactc tatatatgat agaactacca gttgttttat aaggaaggtt tacccattga
   152701 ctgccaatct ttgcttcgtg ttttattata tgctccttat tctccaatga agcgatagga
   152761 gaataatcat ataaaaaata atccattcct ttagtggtat acgcctctac tgtttctttg
   152821 tttacaacaa tatgtcccgg ctgagaaatt attttttgat tgaaattttt tttactagaa
   152881 acagttaaag tgattaataa caaaacagtc ataaataaat aaaatagttc tcttgtctta
   152941 ttgtatcttc tatttttgaa aaatatcatc gttaatatca gagaagagaa tattatttgc
   153001 aagcttaaga tccgccaagg aaattgtaac aatttggctg gcgtattttg cagaagatac
   153061 catggcacca aactagttgt agctagccaa gtcaaacacg taccataata aatctttttt
   153121 tctatgtttg ttaatttttt aaataaaatc aggggaatac ataaagataa cagaccaact
   153181 agtcccattg agtaagtagt taagtcgttg ttcatagctt cagtcagact atcgaacaca
   153241 ttagatgcat gagcatataa atttgtcacg ctaggtttgt tgattttttg gtagagcatt
   153301 tgttcaaaca tcggatacca aaaagcactc gtcagaacca atgtcattcc tgccgcacta
   153361 aataattttt taaatatagc aataaaatct gcattcttga aacctttaga aaccaaacga
   153421 ataaaaatga taattaatgc tgtactcatt aatgttgata gtacatggct gtacactagc
   153481 aaactcatac tcaatgctag ctttacagac ggatactttt cttcttttcc agagatgatt
   153541 tgataagcat aaaataatac agggataaca agtgttattg cgatagcttc ggcaattgcg
   153601 gaacgatagt agatgtctac tgtccgataa gcagagaaaa tatagagaca actaaataaa
   153661 aatgccgctt ttttttgttt taaaaaccgc tcgccataat gataagctac gagtgttgta
   153721 cacaagttca ataaccaaac gtaaataata tagcttacaa tcaaattttt tgtcatccaa
   153781 tataacatta cagctggaaa aaaagtcaga aagggataaa aataatttac accatatcca
   153841 gtataattga atgtctcata attaatcgga ctggtaaaaa tagtcgataa ccccttgatt
   153901 cgagataagt gaaaagaaag atctccagtg gtataaatac tctgtgtatt tttgaaaaag
   153961 atgaaagaat atatactact aactataatt aatccactca atattactac ttttttattt
   154021 attttcattc ttcttgttta tctccttttt agtcacatat cgagaatctt tcaacttatt
   154081 aggtgcaaat cgtttaaaac ttgaatacac cactaaacaa taagtcagaa tactgatcca
   154141 taaagccatg agagcagttg gagtatattt tgttgtaatt tctatcttat tttctccagc
   154201 atttacatcc acattcacta agccatgttt tttataagag tcatttacga ctttaccgtt
   154261 tacttttacc tgtgtaccta aataagcata tactggtact gtcacttttt gctttttgtt
   154321 gcttgccact gtgtaagtaa tgttattatc tgcagcttta tacttccctt tttcccacga
   154381 ttctcctact tttacttcat gtttttctaa gtgaggcctt tcttttatcg cttctgttgg
   154441 ggcgtaatcg tataatcctc ccatatctga tgttgtataa cgtgggagtg tttcttcatt
   154501 gataacaata tgaccgtgtt ttgattggat aacttttgcg taattttctt ttgctgctat
   154561 agacgtgacg agtagaaaca ccacagtagc gccaatgatt aaccatgaat attttttatt
   154621 catagtcttt ttcataaaaa caagcgttat gatcattgaa gaaaaaaaga tttggatacc
   154681 taagatacgc caaggaaact ggagcaagct tatcggtgtt ttttgaaaca aaaaccatgg
   154741 aaataaatta gttacgcata cccatgtaga aactacgcca acatagatga ttttttcttt
   154801 tttctccatt tctttcagta tgaataaagg aaaaatcaac gcaaccaatc ctaataaccc
   154861 catagtgtat gttgtaatat cgttatttaa cgcttgaatg atactatctg aaatagaaag
   154921 tgcttctagc tgcaaatctg ttttgaaggg actgtgtatt tcttgataat tcatctgctg
   154981 caacatagga taccaaaaat agctagttaa tgcacaagtc aaaaaaacag cctttactaa
   155041 attcacgacc acaaatttta tatcgttttt tatttgcttg cttaaaaaca aacgaactat
   155101 aatcatacaa gcaatcaatg cactacacaa tagtgtagtt aagacatgag tatacacaag
   155161 tagacttata ctgacagata aagcgatgac ttttttttct ctattgaata tcaatccata
   155221 agcataatat aaaacagctg ggataatcgt aagagcgatt gcttctgcaa ttgcggatcg
   155281 ataatagata tcaactgttc gataagttgc aaaagtatat aaacaactaa ataaaaaagc
   155341 agcatctatc tttttaaaaa acttttctcc ataataaaaa c
//
LOCUS       DACBZK010000002       106752 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.002, whole genome shotgun sequence.
ACCESSION   DACBZK010000002 DACBZK010000000
VERSION     DACBZK010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 106752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 106752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..106752
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.002"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(717..3866)
                     /locus_tag="IVD66_000138"
     CDS             complement(717..3866)
                     /locus_tag="IVD66_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HAP6144391.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYNTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3880..5124)
                     /locus_tag="IVD66_000139"
     CDS             complement(3880..5124)
                     /locus_tag="IVD66_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAP6144392.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELIKFKLEPGDFIMSGAGTIGRIS
                     RVPKQIKPGVFNQALIRLRINKEITDSEYFIQFIRADFMQRKLTGANPGSAITNLVPM
                     SEVKKWIVQFPILEEQKKIGNFFKQLDDTIALQQRKLDLLKETKKGFLQKMFPKNGAK
                     VPEIRFPGFTEDWEQRKFKEFSKKTGKKNTKDLDFPAYSVSNKAGLISQTEQFDGSRL
                     DDLEKTNYKFVEPNEFAYNPARVNVGSIAFNNLGMTVIVSSLYVVVKMSEDLDNEFIL
                     QFIKSPTFIKEVKRNTEGSVREYLFYENFANIKFPFTRNKEEQQKIGAFFKQLDDTIA
                     LHQRKLDLLKETKKGFLQKMFV"
     gene            complement(5117..6709)
                     /locus_tag="IVD66_000140"
     CDS             complement(5117..6709)
                     /locus_tag="IVD66_000140"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HAP6144393.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(7218..7943)
                     /locus_tag="IVD66_000141"
     CDS             complement(7218..7943)
                     /locus_tag="IVD66_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144394.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(8097..8423)
                     /locus_tag="IVD66_000142"
     CDS             complement(8097..8423)
                     /locus_tag="IVD66_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144395.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(8460..8825)
                     /locus_tag="IVD66_000143"
     CDS             complement(8460..8825)
                     /locus_tag="IVD66_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HAP6144396.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(8862..9077)
                     /locus_tag="IVD66_000144"
     CDS             complement(8862..9077)
                     /locus_tag="IVD66_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6144397.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            9206..9541
                     /locus_tag="IVD66_000145"
     CDS             9206..9541
                     /locus_tag="IVD66_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6144398.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(9617..11614)
                     /locus_tag="IVD66_000146"
     CDS             complement(9617..11614)
                     /locus_tag="IVD66_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144399.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(11712..11987)
                     /locus_tag="IVD66_000147"
     CDS             complement(11712..11987)
                     /locus_tag="IVD66_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6144400.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            12219..12953
                     /locus_tag="IVD66_000148"
     CDS             12219..12953
                     /locus_tag="IVD66_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6144401.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            12992..14134
                     /locus_tag="IVD66_000149"
     CDS             12992..14134
                     /locus_tag="IVD66_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6144402.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(14229..15620)
                     /gene="sufB"
                     /locus_tag="IVD66_000150"
     CDS             complement(14229..15620)
                     /gene="sufB"
                     /locus_tag="IVD66_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HAP6144403.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(15625..16095)
                     /locus_tag="IVD66_000151"
     CDS             complement(15625..16095)
                     /locus_tag="IVD66_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HAP6144404.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(16082..17317)
                     /locus_tag="IVD66_000152"
     CDS             complement(16082..17317)
                     /locus_tag="IVD66_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP6144405.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(17314..18600)
                     /gene="sufD"
                     /locus_tag="IVD66_000153"
     CDS             complement(17314..18600)
                     /gene="sufD"
                     /locus_tag="IVD66_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HAP6144406.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(18613..19386)
                     /gene="sufC"
                     /locus_tag="IVD66_000154"
     CDS             complement(18613..19386)
                     /gene="sufC"
                     /locus_tag="IVD66_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HAP6144407.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(19583..20431)
                     /locus_tag="IVD66_000155"
     CDS             complement(19583..20431)
                     /locus_tag="IVD66_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6144408.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(20455..21141)
                     /locus_tag="IVD66_000156"
     CDS             complement(20455..21141)
                     /locus_tag="IVD66_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6144409.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(21134..22168)
                     /locus_tag="IVD66_000157"
     CDS             complement(21134..22168)
                     /locus_tag="IVD66_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6144410.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            complement(22563..22901)
                     /locus_tag="IVD66_000158"
     CDS             complement(22563..22901)
                     /locus_tag="IVD66_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HAP6144411.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(22903..23259)
                     /locus_tag="IVD66_000159"
     CDS             complement(22903..23259)
                     /locus_tag="IVD66_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HAP6144412.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(23265..24452)
                     /locus_tag="IVD66_000160"
     CDS             complement(23265..24452)
                     /locus_tag="IVD66_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP6144413.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(24643..25488)
                     /locus_tag="IVD66_000161"
     CDS             complement(24643..25488)
                     /locus_tag="IVD66_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP6144414.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            25722..26687
                     /locus_tag="IVD66_000162"
     CDS             25722..26687
                     /locus_tag="IVD66_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HAP6144415.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            27064..28107
                     /locus_tag="IVD66_000163"
     CDS             27064..28107
                     /locus_tag="IVD66_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HAP6144416.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(28169..28633)
                     /locus_tag="IVD66_000164"
     CDS             complement(28169..28633)
                     /locus_tag="IVD66_000164"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HAP6144417.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            28879..29826
                     /locus_tag="IVD66_000165"
     CDS             28879..29826
                     /locus_tag="IVD66_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP6144418.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(30037..32109)
                     /locus_tag="IVD66_000166"
     CDS             complement(30037..32109)
                     /locus_tag="IVD66_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP6144419.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(32042..32419)
                     /locus_tag="IVD66_000167"
     CDS             complement(32042..32419)
                     /locus_tag="IVD66_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HAP6144420.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(32548..33108)
                     /locus_tag="IVD66_000168"
     CDS             complement(32548..33108)
                     /locus_tag="IVD66_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6144421.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            33258..34550
                     /locus_tag="IVD66_000169"
     CDS             33258..34550
                     /locus_tag="IVD66_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP6144422.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(34610..35728)
                     /locus_tag="IVD66_000170"
     CDS             complement(34610..35728)
                     /locus_tag="IVD66_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HAP6144423.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(35742..37163)
                     /gene="arcD"
                     /locus_tag="IVD66_000171"
     CDS             complement(35742..37163)
                     /gene="arcD"
                     /locus_tag="IVD66_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HAP6144424.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(37409..38530)
                     /gene="mnmA"
                     /locus_tag="IVD66_000172"
     CDS             complement(37409..38530)
                     /gene="mnmA"
                     /locus_tag="IVD66_000172"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HAP6144425.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            38934..39533
                     /locus_tag="IVD66_000173"
     CDS             38934..39533
                     /locus_tag="IVD66_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphatase"
                     /protein_id="HAP6144426.1"
                     /translation="MNYFISDMHFFHEHLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(39671..40957)
                     /gene="efmA"
                     /locus_tag="IVD66_000174"
     CDS             complement(39671..40957)
                     /gene="efmA"
                     /locus_tag="IVD66_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HAP6144427.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(41228..41572)
                     /locus_tag="IVD66_000175"
     CDS             complement(41228..41572)
                     /locus_tag="IVD66_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HAP6144428.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(41709..42845)
                     /locus_tag="IVD66_000176"
     CDS             complement(41709..42845)
                     /locus_tag="IVD66_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP6144429.1"
                     /translation="MKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAH
                     EKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIEHPA
                     VLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK
                     EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV
                     NIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLILDTL
                     EANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNIEPS
                     HVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(43034..44008)
                     /locus_tag="IVD66_000177"
     CDS             complement(43034..44008)
                     /locus_tag="IVD66_000177"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAP6144430.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(44088..44963)
                     /locus_tag="IVD66_000178"
     CDS             complement(44088..44963)
                     /locus_tag="IVD66_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HAP6144431.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            45093..47000
                     /locus_tag="IVD66_000179"
     CDS             45093..47000
                     /locus_tag="IVD66_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HAP6144432.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(47541..50819)
                     /locus_tag="IVD66_000180"
     CDS             complement(47541..50819)
                     /locus_tag="IVD66_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HAP6144433.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(51090..51635)
                     /locus_tag="IVD66_000181"
     CDS             complement(51090..51635)
                     /locus_tag="IVD66_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP6144434.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(51647..52339)
                     /locus_tag="IVD66_000182"
     CDS             complement(51647..52339)
                     /locus_tag="IVD66_000182"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HAP6144435.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(52358..52642)
                     /locus_tag="IVD66_000183"
     CDS             complement(52358..52642)
                     /locus_tag="IVD66_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144436.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(52655..53218)
                     /locus_tag="IVD66_000184"
     CDS             complement(52655..53218)
                     /locus_tag="IVD66_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAP6144437.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            53446..54108
                     /locus_tag="IVD66_000185"
     CDS             53446..54108
                     /locus_tag="IVD66_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     protein"
                     /protein_id="HAP6144438.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            54232..55428
                     /locus_tag="IVD66_000186"
     CDS             54232..55428
                     /locus_tag="IVD66_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HAP6144439.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(55529..56905)
                     /locus_tag="IVD66_000187"
     CDS             complement(55529..56905)
                     /locus_tag="IVD66_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6144440.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(56942..57808)
                     /locus_tag="IVD66_000188"
     CDS             complement(56942..57808)
                     /locus_tag="IVD66_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HAP6144441.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(57897..58922)
                     /locus_tag="IVD66_000189"
     CDS             complement(57897..58922)
                     /locus_tag="IVD66_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP6144442.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(58940..59614)
                     /locus_tag="IVD66_000190"
     CDS             complement(58940..59614)
                     /locus_tag="IVD66_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6144443.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(59798..60691)
                     /locus_tag="IVD66_000191"
     CDS             complement(59798..60691)
                     /locus_tag="IVD66_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP6144444.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(60765..62462)
                     /locus_tag="IVD66_000192"
     CDS             complement(60765..62462)
                     /locus_tag="IVD66_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP6144445.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(62455..63768)
                     /locus_tag="IVD66_000193"
     CDS             complement(62455..63768)
                     /locus_tag="IVD66_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP6144446.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(63768..67286)
                     /locus_tag="IVD66_000194"
     CDS             complement(63768..67286)
                     /locus_tag="IVD66_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAP6144447.1"
                     /translation="MDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEK
                     KEISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMV
                     NFYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETL
                     YKDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDV
                     LFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGS
                     SNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAI
                     GRNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVS
                     PFGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYK
                     FSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSS
                     SIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFET
                     KMPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEY
                     TSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNI
                     NKLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDG
                     KYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRL
                     YDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTL
                     DGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQP
                     LHLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIID
                     GVLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPND
                     SSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTL
                     KVEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYIL
                     LAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(67579..68037)
                     /locus_tag="IVD66_000195"
     CDS             complement(67579..68037)
                     /locus_tag="IVD66_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP6144448.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(68335..68853)
                     /locus_tag="IVD66_000196"
     CDS             complement(68335..68853)
                     /locus_tag="IVD66_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAP6144449.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(68855..69472)
                     /locus_tag="IVD66_000197"
     CDS             complement(68855..69472)
                     /locus_tag="IVD66_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAP6144450.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSFYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(69469..70323)
                     /locus_tag="IVD66_000198"
     CDS             complement(69469..70323)
                     /locus_tag="IVD66_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6144451.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(70320..71231)
                     /locus_tag="IVD66_000199"
     CDS             complement(70320..71231)
                     /locus_tag="IVD66_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6144452.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(71272..72606)
                     /locus_tag="IVD66_000200"
     CDS             complement(71272..72606)
                     /locus_tag="IVD66_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6144453.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            72814..73644
                     /locus_tag="IVD66_000201"
     CDS             72814..73644
                     /locus_tag="IVD66_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HAP6144454.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(73888..74137)
                     /locus_tag="IVD66_000202"
                     /pseudo
     CDS             complement(73888..74137)
                     /locus_tag="IVD66_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(74328..74522)
                     /locus_tag="IVD66_000203"
     CDS             complement(74328..74522)
                     /locus_tag="IVD66_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144455.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(75027..75212)
                     /locus_tag="IVD66_000204"
     CDS             complement(75027..75212)
                     /locus_tag="IVD66_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144456.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(76062..76403)
                     /locus_tag="IVD66_000205"
     CDS             complement(76062..76403)
                     /locus_tag="IVD66_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP6144457.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(76403..76633)
                     /locus_tag="IVD66_000206"
     CDS             complement(76403..76633)
                     /locus_tag="IVD66_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP6144458.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            76920..77258
                     /locus_tag="IVD66_000207"
     CDS             76920..77258
                     /locus_tag="IVD66_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144459.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(77463..77702)
                     /locus_tag="IVD66_000208"
     CDS             complement(77463..77702)
                     /locus_tag="IVD66_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HAP6144460.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(77678..78025)
                     /locus_tag="IVD66_000209"
     CDS             complement(77678..78025)
                     /locus_tag="IVD66_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF159 family protein"
                     /protein_id="HAP6144461.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(78757..79338)
                     /locus_tag="IVD66_000210"
     CDS             complement(78757..79338)
                     /locus_tag="IVD66_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6144462.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLVKERLLTSQKVL"
     gene            complement(79521..80147)
                     /locus_tag="IVD66_000211"
     CDS             complement(79521..80147)
                     /locus_tag="IVD66_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP6144463.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(80169..81500)
                     /locus_tag="IVD66_000212"
     CDS             complement(80169..81500)
                     /locus_tag="IVD66_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HAP6144464.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(81655..82056)
                     /locus_tag="IVD66_000213"
     CDS             complement(81655..82056)
                     /locus_tag="IVD66_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAP6144465.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVFEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(82142..82348)
                     /locus_tag="IVD66_000214"
     CDS             complement(82142..82348)
                     /locus_tag="IVD66_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144466.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(82443..83945)
                     /locus_tag="IVD66_000215"
     CDS             complement(82443..83945)
                     /locus_tag="IVD66_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HAP6144467.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(83963..84418)
                     /gene="argR"
                     /locus_tag="IVD66_000216"
     CDS             complement(83963..84418)
                     /gene="argR"
                     /locus_tag="IVD66_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAP6144468.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(84516..85133)
                     /locus_tag="IVD66_000217"
     CDS             complement(84516..85133)
                     /locus_tag="IVD66_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144469.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            85354..86727
                     /locus_tag="IVD66_000218"
     CDS             85354..86727
                     /locus_tag="IVD66_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP6144470.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            86802..87914
                     /locus_tag="IVD66_000219"
     CDS             86802..87914
                     /locus_tag="IVD66_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAP6144471.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(87986..89623)
                     /locus_tag="IVD66_000220"
     CDS             complement(87986..89623)
                     /locus_tag="IVD66_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HAP6144472.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAVVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(89791..90399)
                     /locus_tag="IVD66_000221"
     CDS             complement(89791..90399)
                     /locus_tag="IVD66_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP6144473.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(90784..91935)
                     /gene="queG"
                     /locus_tag="IVD66_000222"
     CDS             complement(90784..91935)
                     /gene="queG"
                     /locus_tag="IVD66_000222"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HAP6144474.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(91954..92706)
                     /locus_tag="IVD66_000223"
     CDS             complement(91954..92706)
                     /locus_tag="IVD66_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144475.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKNADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(92847..93797)
                     /locus_tag="IVD66_000224"
     CDS             complement(92847..93797)
                     /locus_tag="IVD66_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAP6144476.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(93798..94637)
                     /locus_tag="IVD66_000225"
     CDS             complement(93798..94637)
                     /locus_tag="IVD66_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAP6144477.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(94634..95380)
                     /locus_tag="IVD66_000226"
     CDS             complement(94634..95380)
                     /locus_tag="IVD66_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAP6144478.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            95618..96988
                     /locus_tag="IVD66_000227"
     CDS             95618..96988
                     /locus_tag="IVD66_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6144479.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(97043..97939)
                     /locus_tag="IVD66_000228"
     CDS             complement(97043..97939)
                     /locus_tag="IVD66_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP6144480.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(98220..98897)
                     /locus_tag="IVD66_000229"
     CDS             complement(98220..98897)
                     /locus_tag="IVD66_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP6144481.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(98988..99893)
                     /locus_tag="IVD66_000230"
     CDS             complement(98988..99893)
                     /locus_tag="IVD66_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP6144482.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLLRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     KNFKNIALDTLKKQLEKQTTVSWTT"
     gene            100068..101522
                     /locus_tag="IVD66_000231"
     CDS             100068..101522
                     /locus_tag="IVD66_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6144483.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFSFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVDPSH"
     gene            101538..102569
                     /locus_tag="IVD66_000232"
     CDS             101538..102569
                     /locus_tag="IVD66_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAP6144484.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGHFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            102576..103763
                     /locus_tag="IVD66_000233"
     CDS             102576..103763
                     /locus_tag="IVD66_000233"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HAP6144485.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            103919..105301
                     /locus_tag="IVD66_000234"
     CDS             103919..105301
                     /locus_tag="IVD66_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAP6144486.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            105273..105659
                     /locus_tag="IVD66_000235"
     CDS             105273..105659
                     /locus_tag="IVD66_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144487.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(105859..106527)
                     /locus_tag="IVD66_000236"
     CDS             complement(105859..106527)
                     /locus_tag="IVD66_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HAP6144488.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT        30580 a        22270 c        18799 g        35103 t
ORIGIN      
        1 gactaataca ggtagtcctc ttttttgtta ttttgatatt ctaaatcatt ttttattgga
       61 ttattccctt gttcgatata gacccaaatt gatctatcaa taattatcaa actgagtcat
      121 atagagacaa aaatttcaaa aatgacctgt taaatggtca tcgaatatca tttaaaatca
      181 atacgacgga gtcagacacg gagtcaaaac aagcccgctg agagtaaaaa atatatacag
      241 tcccataggt aaagtgccac aggactgtat atttttttat ttgagattac ctgaaatgat
      301 tccatttact ttttatctca ttttttccta ctagttagta tcaaatactc tcctattttc
      361 tcaataaact attttgggtt acatggtatc tgaaacagct aaaaccttgt cattacagca
      421 aaaaatcact ttatctccgt ttcatttcag atacatttca cttaagcgga ttccaaaaaa
      481 acaaaagaaa aaggaacccc tagttagcct atgcttttta ttggttcctc tcaaaacacg
      541 gtcatataac aacggggtgg ggtaaatgaa tgaaaaaggt ggaggaaaca ttattcaata
      601 gctgtcttaa atacttcgtt ataaaatgtg aacaaataaa agacatctat ccctattttc
      661 tacacttcca ctttactacc atctttgaat cgtacaattt tcttaactct tctcgtttac
      721 ctcaattcat tttcaagtgg aatcagctca tcatctaaca ttttacgcca tgctcgcttc
      781 atttcttgtg ggtatttaaa tggcttcgct tctggatggt tggctttata tccttcgtaa
      841 tccttactgt tgataattgc tttcatatta ggaattggat cttcacctgg catatattgc
      901 agattagaag catgtaattc tttctcagaa acaaaccact cattggaaaa gacatgaatc
      961 aaatcatcac tcgcttgtgt aaaatagcga cgtttaatga caaagatatc ttcattacta
     1021 tctaaagtcc ccacatcaaa cgcatttaaa atttgtcggt aaacttcttt gactccttct
     1081 gttttattca atttagccaa agctttttca atttcttctc gtgcatctga actattcgcc
     1141 gcataagttc ctagtaattg atcaatataa gtagaatcaa tatcatacaa cttcgtggta
     1201 ttttcactat aaaattcgat cgtggaaaaa tcttctccct ctttttctgg ttcttcctct
     1261 attaatgaac ccttcacggt ctcgtacacg ccaatttgtt cttccaaaag ttgaatttga
     1321 ttgttcaagg ttgaagattt caccatgtca tcattgtaat cgtcataagt cactaacgat
     1381 tcataagcac gattcaattc ttggaatgct ttgacgtact cgatacggat ttcaagtggc
     1441 gtatgttcat caatggattc catggatgaa acctctttta acttaccata tgcttgcttg
     1501 aatctttttt tggattcctg ataacttgga taaatcaaac ccgattcttc ttttgcttct
     1561 gaatacagtt ttgtcgcatc ctcgacattc ttctccattg tggctggctt tcggaaagta
     1621 acaattagtc cttttgtttt ttctggatac gtacggttcg tacgtgaaaa agcttggatc
     1681 aatcctgcat actctagatt acgatccaca aatagggttt gaatcgtagg tgcgtcaaaa
     1741 cctgtcaata gacgatccac tacgatcact aaatcaattt gtttcccaaa ttgtttgaat
     1801 tccgctcttt ttcgtgccaa acgattattg atgtctccgt tataacgctc aatgtctgct
     1861 aatgaccagg aagtattata atactgatta tattcctcaa taattttttg catttcttct
     1921 tgttggacac ttgaatctcg gctgttttct tctaatgaat aggtaatagc gattcgtgga
     1981 aaatcaggat cctccatcgt tcttccttca cgaatgggct gattaggaaa ctcttttgtt
     2041 aaccagtcag gttctttcgt catttctttg atcgctcgat aatacttttt ggccatgtca
     2101 atggaactcg tggttaagat cgcagacttc gttggacggc catttcgaaa atcaaatttt
     2161 gtataggcat tgtctggacg gaacatttta tgaatgactt tttggatatg ttcatctgct
     2221 tcaaaaacag tagggtccaa ataactttct tttttgacag gctccatttg atcaatcata
     2281 cgattgatct gttccggtga atactctgca tatgtttcta cttcttttaa tttccgatag
     2341 attttattct ctaatgaagt cggctccacg gtgttttcat gctctacttg aaatcctaaa
     2401 accgagccat cttctaatgc attcttgatg gtataggtat gcaagacctc tccatactga
     2461 tcatgggtcg tacgtgccaa ttgccctttg gcttgtttcc gattctcagg gaaaatcggt
     2521 gtacctgtaa agccaaacca agtggatttc ggaaacattt ttttgatttc ttccatattt
     2581 tcagcactta acgctcgatg acactcatct actacaaaca cgatatgttg ccccattaat
     2641 ttttggaagc gattggttcc ttttttctct tcttgttttt ttgcatattt caacgccgca
     2701 tctagctttt gacgggttgt aataatcaca acatttgcat tggcatctgc caacagagtt
     2761 tcacttaact ctttggcact tcctgttccc acgatcaagc tattcgcttt ggcgttcccg
     2821 gaagaaatcc cagtattaaa ttccgaagca aatttcgtaa actctgtggt ggtttgatta
     2881 tctaaatctt tgcggtccac taacatgatc gtccgatcga tccccgattt tcgtgctaaa
     2941 agcttagtag atacaaaact agtcaacgtt tttcctgaac cagtcgcatg ccacacatat
     3001 cctgattgat gtttatttgc agcaataaac aaggcttgaa tcgcatgtac ttgataagga
     3061 tgtaacacca tgaggatttt attgtcttga tcttcactga caatcgtata atccgcaatc
     3121 aagcgatgag catccgggat atttagcact tgtttgcaaa actcatataa gttttctacc
     3181 tttttattat ctttcgttcg ccaactaaat aaaaacttag gatgcaaatc ctttggtaag
     3241 gcatttgcaa aataccgagt ggtttgttca ttggaaacca caaacaactg taaggtcgaa
     3301 aagatattgt tccgaaacat accttcttct gcatattttt tgatttggtt aaacgcctga
     3361 taaaaactat cttttgcggt tacttgtttc agctcgattt ggacaatcgg taatccattg
     3421 atcagtaagg tgacgtcaaa acgtcgatcc cgtgcttcta tgttacttcc acgttttgca
     3481 atttgatgga ccacttcata ggtagagatt cctccaccaa tgtcttgatt agaataaaga
     3541 atgagcgaga cagaacccag ttgcggatct tcccgttcaa tcgtgatccg agccattcca
     3601 ttttcacctt ttaaccattt cgcagcatca aagggggttt tcgttcgtag taacaattct
     3661 gttttgatcg tttcaaattc tttatcggtc aaaggaaaat cattcagttc tgcttgatta
     3721 tttgagatga ttttttggcg taaattgacc caaagatctt cttctgattt tagatcggga
     3781 cgatacgtcc actgattatg cccttccccc aatacacgga tcaactgttc ttcgacttcc
     3841 gcttcctcac ggtgactaat tttcatttat cttccctccc taaacaaaca tcttttgtaa
     3901 gaagcctttt ttcgtttcct tcagcaaatc taacttacgt tgatgaagag cgatcgtgtc
     3961 gtcgagttgt ttgaagaaag cgccgatttt ttgttgttcc tctttattcc tagtaaaagg
     4021 aaacttgata ttagcgaaat tctcatagaa taagtattct cgtacgcttc cttcagtgtt
     4081 gcgcttgacc tctttgataa atgttggtga cttgataaac tgaagtatga actcattatc
     4141 taagtcctcg ctcattttca caactacata aagagagcta acaatgaccg tcataccaag
     4201 attgttaaat gcaattgatc ctacgtttac tcttgctgga ttataggcga attcatttgg
     4261 ttcaacgaat ttataatttg ttttttctaa atcatccaac ctactaccat caaactgttc
     4321 tgtttgagaa attaaacctg ctttattact taccgaatag gcagggaagt ctaaatcttt
     4381 cgtgttcttt tttccagtct tcttactaaa ctctttgaac ttacgctgtt cccaatcttc
     4441 cgtaaatcca ggaaaccgaa tttctggcac ttttgctccg tttttaggga acattttttg
     4501 taagaatcct tttttcgttt cctttaataa atctagctta cgttgttgaa gagcgatagt
     4561 gtcgtccagt tgtttgaaga agttcccaat tttcttttgt tcttctaata ttggaaattg
     4621 tactatccat tttttcactt ctgacattgg tacgagattt gtaattgctg aacctggatt
     4681 agctcctgtg agttttcttt gcataaaatc tgcacgaata aattgaataa aatattctga
     4741 atctgtgatt tctttattta ttctaagtct aatcaaagcc tgattgaata cacccggttt
     4801 tatttgcttt ggtactcttg aaattctccc aattgttcca gcgccactca tgataaaatc
     4861 gcctggttct aatttaaatt tgattaattc attatatttt ttttcagtaa ttttatatct
     4921 tgtttcgtaa ttatcataaa tagcattttg ttgttcatag acaacaaaat tgctattaga
     4981 tacaaagaat tctttcttta aggcactccc aaatggtccc ctccttactc catctttttt
     5041 atcaagtaag cattcaaact tacgctgttc ccaagcttcc gtaaatcctg ggaaacgaat
     5101 ttctggttgt atatcattac tcatgtttga acacctccag cgcaccttgt aaccacgctt
     5161 cattttcagg tgttgtttgc agggaagaga tagcttctaa aagttctttt tctagcactt
     5221 gctgttcttg tcgtatcttc ttgatgtcat ttccgacatg aaccatatca attggttctt
     5281 cttcttcaaa cgtatctaca tagcgtggaa tatttaagtt atagtcattt tctttgattt
     5341 catcaaagtt tgccaaatga gcgtatttct cgacatcttt tctttcagca taggtttcga
     5401 ggattttttg aatgttttct tccgataatt tattctgatt ttttcctttg acaaattctc
     5461 gactagcgtc aatgaataat acgtctcgag tttggcggtt ctttttcaat acaatcaccg
     5521 tcgttggaat cgatgtcccg aagaacaagt tcgcaggcat accgatcaca gcataaatac
     5581 tgccgtcttc tagtaatttt tgacgaatga ccccttctgc agcgccacgg aataaaactc
     5641 cgtgtggcaa gacgatggcc atagtccctg tttccttcaa atgatagaaa ccatgaagaa
     5701 gaaacgcaaa atctgctttg gattttggcg ctaattttcc ataacgatta aaccgagaat
     5761 cgtctaagaa ggtcgtatct gctgaccaat tagccgaata aggtgggttc attactactg
     5821 catcaaatgt gtaaggttca tctgttggcc aatccttatt caacgtatcc ccattgcgga
     5881 gattcatttc ttcggcatct accccatgta aaatcaagtt catttttgct agattgtatg
     5941 tcgttgtatt taattcttgc ccatgatatt taacgttatc tgggtgagtt aagtagttac
     6001 gcacatttaa catcaatgaa cctgaaccca tggttggatc aaaaacacta aagaatcgtc
     6061 gttctttttg atccaacgtc acgatttgtg ccatcatatc agaaaccata tgaggcgtgt
     6121 aaaattctcc ggctttcttc cctgcttctg aagcaaattg actgatcaga aattcataag
     6181 catccccgat cacgtcccca tcgtgaccta aaacttccac gtcattcaat ttcttaatga
     6241 cttcggtaat cgtcacattt cgttgttgct catctgttcc tagttttttt gattggagat
     6301 ccacatcatc aaataaccca ttaaattgat tgtaggtaga tgccaattgc acaaaggctt
     6361 tgtttagatc attcaattgg aacgttgctt gttttgcttg atccgctaag acgttgaaaa
     6421 gatactctgg cgaaatcgca taccccaaaa tatcaacgat tgttgcaatc agatcttctt
     6481 ttgattcttc atctgaaagt aattcgcgat acaacatcgt ttgtttgctt accgtatcat
     6541 attcctctaa ggattcatct gctaaaagaa ccacttgttc caacaaacgg tcggataaat
     6601 atttatagaa aatcagtccc aataaataat ttttatattc tgacgcatcc attttgctac
     6661 ggagattatc tgccgcacta aataattttt gatttaattc tgcacccaaa aagatacact
     6721 cctatctctt atttaaagtt gctatatacc ctcttatttt agcatactcc cttttagaaa
     6781 aagcaaaaaa aaaagaaaga aacttattct tgctaataaa ctacgcgaaa ggagtctaac
     6841 gttgtttgat ataacttaga ctgatcgtta acttattttt tatatttcta catagttatc
     6901 tttagaacca tttcagatac atatgaaaca attacatatg attttttcat aaaaaaacag
     6961 tactgtctag tagtataaaa tatacaaatt tcttaaaaat tttttcacta aaatcactac
     7021 ctgaaacagt ctaaaacact tatatatcaa cgtttaatga aactatctcc gtttcatttc
     7081 agatacaaat aaatatagtc gggctccaaa tccgaaaaaa aataccccca gtagcttatc
     7141 ctaagctact ggagatgtat aagtacggtc atataacaac ggggtagggt aaataaatga
     7201 aaaagatgga agaatcatta ttcaataact tttttaaata cttcgttgta atcagttacc
     7261 tgtccgttct taaataccac agaataatct tttttcccat tttcaagtaa ccgaagtgga
     7321 atatctttac caactttctc tgtcactgca ttactgatac ctgttagatt agctaataaa
     7381 tctgataaag attgagcatc tgtagaaatc tctgtatcag tatttatcgt gattccttta
     7441 tcttcattta caagtttcca agtaggtggt atagctgtgt atgtttctac aaatgaatta
     7501 agtttttcat taagtgactt ctcttttata tttccatcta aaaactctgt atatatggct
     7561 tgagctatac taaaacaaag ctggccttgt tctaataatt ttacatcatt agttagtaaa
     7621 gctgtgttca cgttatcaat cgcttcaaga agagtatctt tggtgtccct aacagcttta
     7681 ggtgtgcctt ctggaatttc cctacttgat acctcgtcca ttttatcttc cataaacccc
     7741 ttaaaatcat atctttctcc caaatccata gaagtttttg agaaagcttt catttctgag
     7801 tctatttctt caataatatt taacatgtct gatacatatt gtttaggctg attcgttttt
     7861 aatctatatg tggtaaatat ctcaattcct ccaattatca ataaaattgc caaacaaatc
     7921 cataataatt ttttcttttt catttttcct cctatacact gctgttataa cagtgactaa
     7981 tgtaaagatt ttcccagcaa tcatcagact attatttaca gggaatcaaa aaaactcctt
     8041 agtaagctta cacctttagg agttcctgtt tgaacggtat gcataataca tttaaatcaa
     8101 tttaacatta acacctcagt atatggtatc tctacatata cacggtcttt ttttggatag
     8161 tactcgacat ttatattgat agcacttcca ttgtctaacg tagctttagc ccggtacgtg
     8221 ttatcaccat tatcatgagt gatcgtcaca tcatcacatg tccgatttaa gttatactgt
     8281 tcttgtaaaa tctgagttac caatggtaca gatgacttct ctagtccaga tgaacccgtc
     8341 attcttgaaa aaattatacc tataatagcc aatacaacga tacctataat gacaaacttc
     8401 ttattcatat ttactttatt caacttttta tctcctatct ccaaaatgat tttctctcat
     8461 cagtaactca ttgacatccc caatagtaca ccaaagatgg ctccagctac ccctgctatc
     8521 atcaaaatcg tacccatttg ttcatctttc tctcgatata agtaacccat aataacagca
     8581 acagcaccaa ataccacagg aataaatgct aatgatacta ccatagaaat ccaaccaata
     8641 atcaaataca gcttccctgt ctcttgtcca tgtacgattt gttccttcat ttcattaatt
     8701 gtctgctcag tacttttctt tactgtgtct gttccggttg tctcatctgt ttcttgtaat
     8761 gctccgcaaa actggcaata cttactttca tttgttattt ctttaccaca ttttctacaa
     8821 tacatgtctt ctcctcctaa aatcattcaa ttgcttatta gctaactgtt tactttatta
     8881 aatacatcag aaaacagctc atttattggt acacttaata tctcagaaag cattttcatt
     8941 tgatagggtt taggaatcgt tctccctgtt tgccacgaac ttacacattg ctgtgtaaca
     9001 ttcatttttt tggctaactc agtttgggaa agtccttttt cttttctgta tcggctgaga
     9061 ttacttactt ttttcatgat tctcccctcc tgttttatta tatacaacaa tatgatgtat
     9121 ttcaactcat aaaatatata aatacttcaa atgtcattac aaatacaaca acttgttgta
     9181 ctctactgag aaggggggtg tattaatgaa acagaagcaa tatgcaaagg tcattagaga
     9241 aaagcgaaaa gcactcgggt ggacacaaaa agaattagct aaaaaaatct tctctacaca
     9301 acaggcagta gcaagatggg aaaattctgt aacagaacct aacctcgata gcttaacagc
     9361 tctttctaga gccctaggaa cccctgtaag ccattttcta gacaatgttg acatagatta
     9421 tgaggaagag tttttggctc tctatcgctc tcttagtact gaagatgcaa ttcgaacaat
     9481 tgactatatg aagctattaa aaaggcaaga aaatgaacgc aatcagctat tgaaagattg
     9541 aaaaataaat aacccaccga actttaacgg tgggtgtatt gagatgaaat aagattaaga
     9601 gctatggata acctgtctag tttaatataa ttgggtctct tctattcctt actctccgtc
     9661 catcatctct tgttacactt gtaaattgat aaataggaac taattcaact cctgataata
     9721 tcaattcttt tattacttca tctatccctg cccctttcgc tagatatact aaaaaactac
     9781 tgcttgcttt cacattgtat agtttcttaa tatccttaga agctcgttca agagtgaatc
     9841 cttgtttaac aaagtagcct ctgttttcta ttaaagcatt tttcacgctg ttatccctga
     9901 catttcgtag gcgttcacaa acagtgttaa taagttcttt ttctgtcatt agatatgtcc
     9961 cttgccacga taagccctgt aaaacttcat gtgcttcatc taaaatcaat tgtttttcct
    10021 tgctaagttc tgatcgggaa ttttgaggaa atactctttt agcctctttt tcgttaaaac
    10081 atatcttaac ccattcataa gaaaaatatt gatatgtaaa atgaaatttt tccagaagtg
    10141 gaaggatatc ttcattcaat ttttgaatca cagaagttgc attaaaaacg tctaatcgat
    10201 agacattgct tctcttatgt ttaaagtttc ctaacgcttt ctcttccttt aacctattta
    10261 ggtattcgag catcttcaaa ggaacatctt catcatctaa tttttttatc aatcctataa
    10321 aagtcataag tgatagtaac ttattacatt tatctatgtc ataagtttta ccatagtaag
    10381 aactcatttt tttagctaat tgttcccccg acaaaataca agtcacactt tccttactat
    10441 catcaaaaaa attaacatca gaaagcaaga catcatagac acgtcgcatt tcctctagat
    10501 aattccttat tgtcctgaaa agtttgtctt tcattgattc aagagtgtca aaaagtactt
    10561 ttgattcctc tttcaatttt cgaaaatgtg taggatacaa gtctaggttc tctaatagcc
    10621 aattaaatgt ttctacccga ctgtctttct ttaaaattag catcacaact ccaataaaat
    10681 tttcactgat atcacaatta ctggaatgac aataaaaaat ggaatgccca gttttactgg
    10741 taaaaatact agcagaggga ttatgatcgt tgtgaaacag acatcttaag tttttacttg
    10801 acttaagtaa tttattcata tcaatggtta acaatctttc ataaatctca ttaaaagaca
    10861 tgtcggagga atcaaacagg cagtctttaa accactgttt catttcttct ttgtcgtcat
    10921 tttttatcaa cttaacaaaa tcggtttcat tgactagttc atactctctc cctgaatcac
    10981 tttgacaatt tttagaacat gtcatggtaa aatcaatcgg aagctcagta atatctaaca
    11041 tgttgtcttc attaattatt atcactgcat ctgacttata tcctccaaaa aacattctat
    11101 tcgaagcatt tacattgtca tcacacccgg ggatgttctt tttcaagtat tcgtaaacag
    11161 caaccatttt accatagtca gtaattgctt cttttaatag aaagacaatc ttgtattttt
    11221 ctagattttc agagtaccga atactttttt gtatcgcaaa cgcagaatta tgaactaaat
    11281 tgatagataa aaccttttct atgcttaagt atctactatc atctttactc aaatctacta
    11341 ccttcccctt ctcatcttta acagtgttat cgacatccag aataattact ctggtttcca
    11401 caaaactctc cttgtcattg cctttattct ttgtcttgct tggaataaat gattgtgatg
    11461 aatttagtat ctctacaaac tcatctcttg taacttctct atagttatct aaacacctat
    11521 ctcttacatc agttttttct ttttttgtaa ctggcttctc taataatttt tcttgatcta
    11581 cataaattgg aatattaatc attgatgttt ccatttgtgt ttcctcctta taaaattctg
    11641 ttaaagacta aaacatacag ataataaaaa caaactcttt attactatat gttttagtct
    11701 tatttgttta ctcaaccttt ataccgttcc atgaaactat caatatcaga ttttttaaat
    11761 ctaatgaccg tatcaatttt tataacaggt aacccgtatt gagaaacata ttttctaatc
    11821 gttcctactg atacacctag atattcactt gcctgctgat agtccatata ctctagagtg
    11881 actccagaaa taatgtcttc tagcataggc tttagcactg taattatctc tttcacttgt
    11941 tgttcaactt gtatagaaac aatgctatca atgatttgta gagacatatt tccccctcct
    12001 ttcgtgattg cttgaacaaa ttttctaaga attatcttcg tattttttgc tcaaaataaa
    12061 agtattttgt tattaaccga ttaatcaaac aaaaaatgat taccagttca tcgacataca
    12121 cataatacct cgataaaaaa ggggtgtcaa cagctttgta aaatttattt acaacacccc
    12181 ttttttgagg tatactaatt ttaggaggtg tggtcaatat gataaaacgt ccaccaataa
    12241 attatttaga acgaaaaaag atactcggaa caaaaataaa agctataaga aagagtaaaa
    12301 aattaacaca accagcattt ggtcttatga ttaacaacgg tcaattaatt gacaaaaaaa
    12361 ctatctacga atgggagaag ggaacctatt taccaatacc agagcgatta tcccgaattg
    12421 ctgatttggg aaatatgagt atagaggagt tagtttgtgg caatgtagaa gaatatattt
    12481 tgggaattat tctttataga gatagcattg tactagatgg tataacattt ccagataaaa
    12541 acctgttcca gcatcttcgt caacagttcc caccagtaca ctctaattta gatacatggc
    12601 tggatagata ttccaaatta gaaccagaga tgcaagaatt tattgctaac aagacttgta
    12661 ataaagttaa aaatgaaaaa attagtcttt tcaatatctt aaaaatagaa gaattattca
    12721 tcaatgctat tgtagaagaa tttgacaata acattctttt cctcactagc agtatagaag
    12781 aactactaga aagaatggta gatgaatggc tacctattca attgaaagac atgtcttatc
    12841 ccgaagaagc tgtgagagaa attactgata atataaacaa gctagaacaa acgatttcat
    12901 caattgggaa aaaatacact aagaaaaaaa tgaagggagg tgataccatc tagtggtaag
    12961 tactccttgt aaactaagag gagatgattt aatggcaaaa atatcaaagt acaaaaagaa
    13021 aaacggtcaa gtggcgtgga tgtataaagg acacattgcc accgatccac gaactggtga
    13081 aaaaataaat actacgagaa gaggttttag tagcaaacaa gaagctcaaa aagattatga
    13141 cgagtacaga catcaaatat tatacggtgt taaaaagaaa gcacctgata tgacatttga
    13201 agacctgtat aatgaatgga taactcatca gcgtaccagt gttaaagctt caacaatcgc
    13261 aatctcagta agatacgcaa ataatcaaat acttccagca tttggtaagc ttaaactatc
    13321 gaatatctct gtcccatatt gtcaaaaagt ggtagatgaa tggcacagta aatatgaaag
    13381 ttacgattat atgagaaaac agactgcaca aattttacgc tacggggttg caatgcaata
    13441 tattgacaat aatcctatgg aaaaaacact tcttccacga aaaaaagagt atgagaaaaa
    13501 tcgtaaattt tactcaaaag aggagcttaa taatttactg gatgctttta aagattttgg
    13561 taacatgaaa caatacgcct tcttcagatt attggcatac acaggtatga gaaagagtga
    13621 agtactcgct ttacagtgga aagacataga cacgtttaat aaagaactac atgtcaataa
    13681 aactcttgct gtagatgaat ttggtaaagt tataattcaa tctccgaaaa caagagcttc
    13741 tagacgagtt atctctttag atactgagac tctttctatc ctcaacaact ggaaattaca
    13801 gcaaaaagaa gagtatttaa aacttggata caatactagc tctaaagagc aacatgtttt
    13861 tacaacagtt aaaaacactc tatacattcc aaacactgtt aatgattggt taagatatat
    13921 tttgaaaaaa tataacttgc ctcgtattac acctcatggg tttagacata cacatgctag
    13981 tttattatta gaagcaggag aatctgtcaa ggtagttcaa caacgattag ggcatgaaaa
    14041 tagtaaagtg acattagaca tctatgcaca tattacaaat aatgcaccta agaaaacagg
    14101 tcaagacttt gctgatatga tggctcatca gtaaaagagc tggtcaaaat ctggtcattt
    14161 ctagtataca ggcaaaacaa aaaagctaga acccttatat atcaagggtt ctagctccta
    14221 taacaggttt acccaacact gccttccatc tcataactga tcaatcgatt gagttcgact
    14281 gcatattcca ttggaagttc tttggtgaat ggttcaacaa agcccatgac gatcatttca
    14341 gttgcttcag attcggtcag gcctcggctc atcagatagt agagttgttc ttctgagatt
    14401 tttgagactt tggcttcgtg ttctaaagag acttggctgt tgtggatctc attgaatggg
    14461 atcgtatcgg atttcgacca ttcgtccatg atgatcgtgt cacattcgat atgagagatc
    14521 gaacccgcac tgtttttggc aaaggttact tgtcctcgat agtttacttc tccgccgtct
    14581 tttgaaattg atttagagac gatagagcta gatgtatttg gtgcattgtg gatcattttt
    14641 gcacccgtat cttggatttg gtttgctcct gcaaaggcga tggagagcat ggtgcctcgt
    14701 gcaccttttc catctaagta aacacttggg tatttcatcg ttgtttttgc acctaggttt
    14761 ccgtcgatcc attcaacggt tgcgccttcg tatgcttttg ctcgtttggt tactaagttg
    14821 tacacattgt ctgaccagtt ttggatcgtt gtgtaacggc aatacgcatc ttttcttgta
    14881 aagatttcta cgatggcggc atgcaggctg ttacttgaat aagtaggtgc cgtacaacct
    14941 tcgacatagt ggatgcttgc tccttcgtca acaatgatca gcgtacgttc gaattgcccc
    15001 gtgttttccg cattgatccg gaagtacgtt tgtaatggaa catcgacttt gacgcctttt
    15061 ggcacgtaaa taaaggtccc acctgaccat acggctgaat tcagcgctgc taatttgttg
    15121 tcggttggcg gtacaagttt tgaaaagtac tctttgaata attcagggta ttctttcaaa
    15181 gcagagtcag tgtcagtaaa gacgattcct aacttttcga attcatcttt catattatgg
    15241 tacacgactt ctgattcata ttgtgcggaa gcaccggcta gataagctcg ttcagcttct
    15301 ggtataccaa tcttttcaaa tgtatctttg attttttctg gtacgtcttc ccagtcacga
    15361 gcgggtttgt cacttggttt ttggtaatat ttgatggcat cgaaatcgat gtctgaaagg
    15421 tcggggcccc atgtttgcat tggcattttg ttaaatgttt ctagagattt cagacggaat
    15481 tcaagcatcc attctggttc gcctttgatt cttgacatct cacggatcac ttcttctgtc
    15541 aagccttctc ctgtactgaa aaccggttcg acatcatcgt gaaacccgaa tttatattct
    15601 tctaattctg gtacgcccat gttctcactc ctcttccttg tggtaatgat ggaaagctgc
    15661 ggtaccatcg ttttccattg cttttcctag tgctttccag gcaagtgtcg cacatttgat
    15721 ccgagcggga aatttagcta caccaccaag catagcagca tcgcctaatt ggtcgggatc
    15781 tttgacttct tttccttgga caagctgtag aaagtctaca gttaaatgtt ctgcttcttc
    15841 tattgatttt ccgatgacgg cgtctgtcat catcgaggca cttgccgtac tgatggagca
    15901 gccactgccg tcaaaggcga tatttttgat gattccgtct tttacatcga cttgcaattc
    15961 gatcacatct ccacatgtgg ggttgttcaa ttcgatcttg cttgtcgagt cagtcaagct
    16021 tccacgatga tgcggatggg aagaatgatc caagatcact tgacggtata aattgtctaa
    16081 tttagatagt cccatgttgg aaaaactcct ttgttgccat gattgcttca actaaacggt
    16141 cggcgtcttg cgttgtgttg tagaaataaa agctcgcgcg agcagtcgct gatacttcaa
    16201 ggtacttcaa tagcggttgc gcacaatgat gacctgctct gacggctacc ccttccatgt
    16261 ctaaagctgt cgcgacatca tggggatgta acccatccaa attgaatgca acgactcctg
    16321 tccgaaaatt cgggtcttgt ggaccataaa cagtcaatcc atcaattgct tgtaattttg
    16381 gcaacacata agcggctagt tcttcttcat atcgatggat attgtccata ccgagttttt
    16441 gcaaataatc gattgcatgg cctaatgcga tagcgccggc gatatttggt gtccctgctt
    16501 cgaatttcca aggtagttct ttccatgtac tgtcgtataa ttcgacaaaa tcgatcattt
    16561 cgccaccaaa ttcaacaggt tccatttctt ctaaccattt tcgtttacca tataaaacac
    16621 caatacctgt tggtccgcac attttgtgtc cgctgaaagc aaagaaatca cagtctagtg
    16681 cttggacatc aatggccatg tgcggggcag attgagcacc atctactacg atgaccccgc
    16741 cgttttcatg gacaagttca gctaattctt gaacaggatt gaagacacct aagacattgg
    16801 atacatgagc aatggagacg attttggttt tgtccgtaat ctttttcgct gcatcctcca
    16861 tatccaggaa gccttcttct gttagttcga tatatttcaa gacagcacct gttcgttttg
    16921 ccaactgctg ccacgggata acattagaat gatgttccat gtaagagagc actatctcgt
    16981 ctcctgcttt gatatagcgg tcgccgaagg ttctggctac ccaattcaag cttgtcgtcg
    17041 taccacgagt aaacagcact tctgctgttt cttttgcatg gatgaacgcc cgtacttttt
    17101 ctcttgcttg ttcataatca tgggtcgcgc gttctgctaa cgtatggaca ccgcgatgaa
    17161 cattggcgtt atcgtgttcg taatagtacg ctaatgcctg gagtacttgt tttggctttt
    17221 gggtcgtcgc tgcattatcc agataaacta aaggttcatc attgacgtct tgaaataaga
    17281 taggaaaatc attgcgtagc tttttagcat cgatcatcca ttcaacttcc cttcgattac
    17341 ttcgactaat tctttccgaa cttgttctac agggattgct gttaagacag aaccgaggaa
    17401 tcctcgaatc actaagcgct ctgcttcttc tttatgcaat cctctactca tcagatagta
    17461 catttcttct ggatcaactc gtcctacact ggcagcatgt ccagcagtta cttcgttttc
    17521 atcgatcaaa agaataggat tcgcatcacc acgtgcttta tcagaaagca tcaagacacg
    17581 actttcttgt tgggcatctg caccttttgc ccctttcaag atgtggccga taccattaaa
    17641 ggtcaatgtt cctttttctc ggatcactcc gtgttgcaaa atatgcccga tcgtatgagg
    17701 ggctttattg gttactcgtg tatcgattcc ttggatttgt ctgcccgagc tgattgccac
    17761 gattttgact tctgcgtgtg caccttctcc tgctaaatct gagtcaaagt cagcgatcac
    17821 atgaccgtca ttcatgacac caattgccca gtcgacagaa gcatctcgta aaatgtgccc
    17881 acggcgattc atataagaag taatattttc tcctaattga tctacggctg aatatttgat
    17941 ttttgaacca gctttagcga tgacttccac gatgatatta cctgatgatt ttgctacttg
    18001 ttctttggtt gtctggaaac gttccagata agaaaattca ctatgttcat ctgccacgat
    18061 caacacatgc ttgaagaagt gctcatcgga tgcgccatct tgaatgaata aggactcgag
    18121 tggttcatcg atcacgacat ttttaggcac atacaggaaa ataccgctgt tcataaaagc
    18181 tacatggagt gcagtcaatt ggtcttcgtt catgtttact gcttttttca tataatattc
    18241 ttggactagt tctggatatt cgatcattgc agtgaacaag tcggtaaaaa tgactccttt
    18301 ttctgctaat tccacaggca gttgttcaaa aatcgtccat gaaccttgtt ggacaagcac
    18361 aggattgtct ttcattgcat caaatgccgg aatcgtgcct gtttcactga tggtttgtgt
    18421 ttctttcaca tcaaataacg accagcgatg gaatttcacc cgatcgatat gcggcaatgg
    18481 cagttcatct gctttcgcta gtgcgtcttg acggaaggtt ctcatccaat caggttcgcc
    18541 tttacttaaa gaaaaatcat ttaccgcgtc aagataatcg agccagtttt tttctttcat
    18601 tcttgctccc ccttacgctt cttcttcttt atagtcgatt cctaattctt tactgatacc
    18661 agcgtagcct tctgcttcca gacgtttagc taggtcagca ttccctgtca tgactactcg
    18721 gccttccatc atgatgtgaa cgacatcagg tgtgatatag ttcaataatc gttgatagtg
    18781 ggtgatgatc aatgcaccga aattgtctcc gcgcatttca tttactcctt tagcaacgac
    18841 tttcaaagca tcgatatcca gacctgaatc gatttcgtct aaaattgcaa atgtaggttc
    18901 taacatcaac aattgcagga tctcattccg tttcttttct ccgccagaaa aaccttcgtt
    18961 cagataacgt tcagccattt cttctggcat atttagtaaa gccatttttt catctaactt
    19021 tttcaaaaat gccataacag aaattttgtc gttttcatca cgtttcgcat tgatcgctgc
    19081 acgcatgaat tccgcattcg tgatacctgg tatctcactt ggatattgca tagctaaaaa
    19141 taagccaagt cgcgcacgtt catctacttc caagtctaaa acatttttcc cgtcaaacaa
    19201 aatttcgcct tctgttactt catagtttgg attgcccatg atagcggcag ataaggtaga
    19261 ttttcctgtg ccgttaggtc ccatgatggc atggatttct ccggttttca ttgttaggtt
    19321 tacgccttta aggatttctt tttcctcgat cgacacatgt agatttttta tttctaagac
    19381 agacatgcat tataccccca aattctcttt cgttctcact cattttagac taattgagaa
    19441 tgaagcgcaa tgaccttcct tactaaaatc aaatatcttt tatttattat taaacaattt
    19501 tgatttctaa attagaatag gtataaaaaa gatgagaaat aagccattac agacttattt
    19561 ctcatctttt ttgttccata ccttattttg catcagcctt tactggttta acagagccgc
    19621 cccatttgtc tgtgatccat tcttggactt ctttgcggtg aagcacttca atcagttttt
    19681 tgattttgtc actgtcttca tcacctttac gagtcgcaat aatattcacg taaggagagt
    19741 tgtccttttc aagcaatacg gcatcttcta atggattcaa ccctgcgccg taagcgaagt
    19801 ttgcgttgat tgcaactagg tcaccttcat cattttggta cgtagaagct aaaagtgatg
    19861 ggtcgatcgt atggttgaac ttcaagttct tagggttttc ttcaatatca tcgaatgttg
    19921 ctgtttccag atctactcca tctttgactt tgactaagcc agcatcttgt agaattgtga
    19981 tgatgcgtcc ccagtctgat tcagaatttg aagtaatgat tgttgcacca tcttttaatt
    20041 cggaaacatc tttgactttt ttagagtaca agcccattgg ttcgatgtgg acagcaccgg
    20101 cattgacaaa gtcatatcct ttttctttga tttctttgtt caaataagga atatgctgga
    20161 agtaattggc atcaatgtcg ccttcttcca aagattggtt cggtaataca tagtcatcga
    20221 atttgacgat ttcaagatcg attccttcat ctttcaataa tggtttcaca tgttccaaaa
    20281 tctctgcgtg cggtgtcggt gaagcgccga ctttcaatgt cgtgtcgtct gctttatttg
    20341 ctgaatcttt gctgtcgctg ttgttaccgc atgctgctaa tcctacagtc agcaaaagcg
    20401 ctgctgcaaa tccaaaaatt ttctttttca tatcctacat ccccctatat cctattatct
    20461 tttgtctgtt ttcttagtta agaaatcacc gattccttga acgataaata cgattagtaa
    20521 aataattaaa gtcgcaacga atgtcactgt tagattacca cgctggtagc cttcctgcca
    20581 agcaagacct ccaagtccac ctgcgccgat cgcgccggcc atcgcagtaa atccgatcat
    20641 cgagatcgtt gtaactgtta atccagaaat caatgcggga atactttcag gtatcaagac
    20701 cttccagatg atttcccagt aacttgctcc cattgcatct gctgcttcca gtacaccagg
    20761 gctgacttca cgaaaagcaa tctctactag acgggcataa aatggtgctg cggataaaac
    20821 aagagctgga atggctgctt gcgcacctag catagtgcct acgattgctt tagtaaatgg
    20881 aatgatcaaa accatcagga tcataaatgg cgttgaccgg aaaatattac tgatgatcga
    20941 tacgattcca taaatgattc gagcatacgg tttgtttttg cgtccaatag agtaaaggat
    21001 caatcccaaa actaatccga tgatcgtcac taagaccatt gagattaatg tcatatatag
    21061 tgtatcaagg atagcctgat tcatcgtttc cgggttgatt tgtttaaaat ctagatatgt
    21121 ttctgaaaag cttttatcca cgatggatca cctcaattcc tactccttgt tctttgatga
    21181 acacttctgc ttgatctaat tctttggttt caccagtcat caagacagtc aatgaaccaa
    21241 aggaaccttc tttcacttgt ttgatctttc catacacaac gttgacatcg atgttatagc
    21301 gtcgaatcgc ttgggaaatg actggctcgt tggcatttct ttcgctaaag gtcaaagttg
    21361 ccaaacggcc gcttggattt tctttgatga gttcagctaa tagttctgtc gaatcagctt
    21421 ctggttcgat gtcttgttgt acaaagcgtt tggttacttc ttttttcggt tgtctgaaga
    21481 cagtcaatac gtctccttct tctacgactt tccccaactc catcacagcg actttgttgc
    21541 agattttgcg gatcacattc atttcatgtg tgatcaagac gatggtcaaa ttcaatttct
    21601 tattgatcgc taacaataag tctaatactt cttctgttgt ttgcgggtcc aatgcgctag
    21661 tagcctcatc acaaagcagg atctcaggat catttgccaa tgctcgtgcg ataccgacgc
    21721 gttgtttctg tccgccggaa agttgtgaag gatatgcttg tccgcgtcct tctaacccga
    21781 ctaaacgcaa cagttcttct gcccgttctt tacgtttgct ctttggtacg ccagctaatt
    21841 ccagcggcag ctggatattt tcaagtacag ttcttgacca taacaggttg aaatgctgga
    21901 agatcatacc gattttcttt cggaatgtac gtaattcttt gttttttaat tttgtaatat
    21961 cttgatcgtt tacgatcact tcgccgctcg tgggaagctc aagtccattc aggagacgga
    22021 ctaatgtact ttttcctgcg ccagaatagc cgacgattcc ataaatatcc cctttttcaa
    22081 cgtttagtga aacgtcattg acggcttgga tgtttccgtt tttcccattg aatgtctttt
    22141 tgacattcgt tagttggatt aatgacatgc cattcacatc tttctcttat gatttttcaa
    22201 acaaaaaagc cttcgccctc ttgccttaag caaaaggacg aaagcttgaa cttccgtgtt
    22261 accaccttga tttaccgtta cttcgcaata acagcctctt ccagtacttg gacttagctt
    22321 ctttccgtat actgtcgcgc tgtaacgggc actcccgtag taagtttgct tacgctcgct
    22381 tactctgctc taagaccatc ttccatctca ttttcgttac ccattttcag caaacagggc
    22441 tctcttcaaa cgtccgtgac atgtactctt cttttcaaag ctttctcgtt tcatatagga
    22501 ttgcttatga ttatagcaac tggaagaatc agtgtcaact tttttcaagt gattttctga
    22561 ttttataatt cgtcaaattc ttttggatca acatctttga aacttaagat ccacgcattc
    22621 atttcatctg aatcattcaa gatattgata tcttcaccga ttttatcatt aacagaagaa
    22681 actgtacccg ttagcgggct ggcaaattca ttgaccgctt tttccgcttc aacttcgatc
    22741 agaggttcat ctttttttag cgattgtcct gcttttggca gattggcaaa cgtgatgtct
    22801 ccaagttctt cttgcgcttc atttgtcaaa ccaacacagt attcttttcc attaaataag
    22861 atccaaaggt tgtccttttt cttcaaatgc ttgcctgcca ttttatatca gttctccttc
    22921 ataaattttt tcattgaatc caattgcaac aagctggtcc tctcgtaaga tcagtggtcg
    22981 cttgatcagc ataccatctg tcgataagac ttggctcgct tttgaagccg taaactcgcc
    23041 tacttgatct ttcagtccaa gttcccgata tttcatcccg cttgtgttga acaggcgacg
    23101 gattggtact tgactcgttt ctagccaagt ctcaatcgtt gaggccttcg gtacttcttt
    23161 gatcatatca acggtttgat aactaacgcc atgctggtct aaccacgctt tggctttttt
    23221 gcatgttgaa catttcgggt accagtaaaa ggtgtacaat tttcttacct ccttgaagat
    23281 cttgcaggtg cttcattttg gtatctcatc gataatatca acccgatacc gatcatgttc
    23341 cctaaaatcg aggatcctcc ctgactaatg aaaggcaatg ggatccctgt taaaggaagt
    23401 aatccgatat ttgctccaat attctcaaag acatggaaca gcagcatcat gatcaaaccg
    23461 cttgcgatat aggcgtaaaa ttcattattc gtatcgaaac acacccgaat catacgatag
    23521 attaaaataa aatacaagaa aatgacgaat gcaccaccga taaagccgaa gttttcaccg
    23581 ataacggtaa aaatcatatc ggactcacga acaggcacat agatattgct tacgttgaat
    23641 cctttaccaa acaagccacc ggtaccaatt gccaaaagtc cttgggccgg ctgataactc
    23701 attcctgacg tatcatggaa agggtccagc catgaatcaa tacgtgcaaa ctgataagat
    23761 ttgaatccaa ctttataaag caagtctctt ccgccttcag tcgtaaccaa gaagatcgtt
    23821 cctgctccaa cgactactgc caagattact acaggtgcga tgatgcgcca agagattcca
    23881 gacatcagga aaatcccgcc aaagatcgca agaaagacaa gcatcgttcc aaagtcatct
    23941 tgggccatga tcaatgctaa aaccggtatt gtcacgatca agagcttccc aatcagccaa
    24001 aagtccgatt tcatcgtccg ttcttttact tgcgtattat gtttagttac gatcagtgcc
    24061 atcatcaaga tgtacgcaat cttcatcaac tctgctggct ggaaagtaaa cgcaccgaat
    24121 cgaaaccagt ttttagaccc tgttgaagca gctaaattct gatcatagaa tttgagcaag
    24181 agtcccatta ccactaaccc caaaccataa aggtaaggag tcagtttcca gatccatttg
    24241 gaattcaaat gcatgatgac aacgattgct gccgctccaa ctaaatacca gacaacttgc
    24301 atccctacgc ctttcaagac tgctggattg ttcggatcat ggctaagtgc tacatataat
    24361 gagagcagac caatcaaaca taacagaaag actggtaaaa tcacgccata atcaatacga
    24421 ttatcgttcg aagcttttaa ttttttttcc atgtttcatc ccttttctta aaaaccatac
    24481 tgctgattat tatagcggtc cagttagata atggaaagtc tttccataga catttgggaa
    24541 aaattaactt tccgtttgtg cagttgcttg agcaaatgca gtacaaaagc ctactgctta
    24601 tctttagtgt atcatagaac tttttttgat acatgcaatt atctaccagc tgagattctc
    24661 ctcgctgtga gaagtttctg tgctttcatt gtatcgaagg atctcttcgg caatctctag
    24721 cagctgatca gaaaccagat tggttcgttg gatgaaataa aaatatcgat ggaaattcaa
    24781 cggagtcatt ggcacatttt ctggaacaga gcgcttagac aaaatcgagc gaccgattcc
    24841 ttccttcagc aacgcaacaa ttacatcgtt acttttcacg atcatcttct tatcttggat
    24901 attcatctct tcaaaataac gctgcgtgta atgaaaaaca ccagagtttg cttctcttac
    24961 aagccacaat ttgctttttg ggtccccagc gatgactagc tggtcttcca tcaaagagta
    25021 tctttgtacg ccggaagtct ctaatggctt ttcgataaaa ccaaaatcgg attcatgttt
    25081 cgctacttgt tctaatgatt catgagaatt cgtgatttcg atctcaaaat gcactttagg
    25141 aaaccttttg atcagatgtt tcatcaactg aggcaaaaga tagacagcaa aggtgtggga
    25201 agcaacgatc cgacatactt cttcttcatt ttgttcattg agcaattttt gctgagtttc
    25261 ttcccattct tctaacaaaa ccagtgtccg ttcatataat aagtcggctt gcttagttgg
    25321 aagcatctct tttcttccgt tacgttgaaa aagatcgata ttcaattccc gctccaactg
    25381 tttgatttga ttcgagactg ctggttgaga taaaaacagt acttctgctg ctctggaaaa
    25441 atttcttgtt tcatatactg ctcgaaaagt cgttaataac ttaaacatgg caccacttcc
    25501 ataacttttt atgataatta ctataaaaac tatttgattt aaatatacaa aaaaccatct
    25561 ataatagaaa tgtacaacaa aacagttgct gatccaacta gtaacttaga tgaagacaat
    25621 cagctgtctg cttgctcgta atcatacatt cctattcatt ttacaatgta ttcgttcatc
    25681 ttggtactaa aatctattaa ataaaaagga gaatattata tatgaagaac tttttgaaaa
    25741 ttattccgat cccgatctgc gggttgatcc ttgggttagc ttcccttgga aatctgttta
    25801 aagactatca ccatgttgct ttaggcaatc taactggcgg tatctctatg attcttatga
    25861 tattcatttt tgttaaattg tttatcttat tcgaacacac gaaacaaacg ttgcatgatc
    25921 caatcatcgc ctccgtttca ccaactttta cgatgtcact catggttatt tgtacttatt
    25981 ttgtttcata tgaaagtatt gcaccaattg tcaaattcat ttggctgtgc gctgttatct
    26041 tccaagtgat ccttgtcttt tatttcaatt atcaccatgt tatcaaagct gatctttcaa
    26101 ttgaagcaat ttatccaagc tggtttatca tttacgttgg atttggggtc atcactgtaa
    26161 ctgccgggaa cttcttccca cttattggaa aaattttctt ttggatttca ttgatctgct
    26221 atgcgttctt attgccgatc atcatcaaac gtgtcttttt cgtaagaaat atggctcatc
    26281 cgacacgtcc gctgattacg atcgttgcag cacctggttc tctttgccta acaggttatc
    26341 ttaaaaactt tgctgaacct aatttttatc ttgtcgtagc attgttcgct ttatctcaag
    26401 tattgtattt cgttgtgctg tctatgcttc cacgtttgtt caagcttcgt ttttatccaa
    26461 gctatgcagc ctttacattc ccgcttgtta tctctgcaac agctatattt actactgttc
    26521 attacttcaa cagtttaggt atctatagta gcgtattgga tttcttaaaa gttgcggaat
    26581 gtctgtttgc aagtgtagtt gtcttctacg ttcttgctca ttacgtacgt ttcttaatta
    26641 aagaacatag caaacatgga aaatttgttt ctaaaaaaat cgcttaataa tcgattcaat
    26701 aggttgtgaa aaagctgttc tgcatcaagt aataagaacg gccaaacaaa aacagctgtt
    26761 catgtttttg tactggttgg gcttattacc gcagatgcaa gcttttgaac accgtttacc
    26821 aagaggtcgt aaaagaagtg gtcagcttca agaaataaga aggaatttac gaaaattgct
    26881 tctcaaattt ttgtgaaatt tcggcttatt tccgtagaag ctacttctgg aacaccgttt
    26941 attcgaaaca agaggtcgta caagactttt gtcacgacct cttgttcttt tgtcaaaata
    27001 ctggtttagt gctactatgt tcgagtatgc ttttagtatt tattgacgaa aggaaccgat
    27061 caaatgaaat cattgtcaca tccaataaaa tctgtaaagg attcagcggt ccgcgaaatc
    27121 ttacccggtt tactgctttc ttttgccatc gctgccttca gcaggcttct tgctatttat
    27181 ctgccacagt taggtggagc gactattgct attttattgg gtattttatt aggaaatact
    27241 ttttttaaac agcctgttct agcaatcggc acaaaatttg ctgaaagcaa actattagaa
    27301 ttctctgttt ttttactagg tgcaactgtc acagctcaaa cgattgctca aattggtgta
    27361 aaaggaattg tttttgtgtt actgcaaatg tcagtcacta tcatcggtgc ttacttgatt
    27421 ggtaaaaaac tgcaattcag cgatacttct tctttgatga tggctggagg aaacgctgtt
    27481 tgtggttctt ctgctattgc ttcaatcgcc ccttccatcc atgcgaaaga ggaagaaaaa
    27541 ggacagatca tcacactagt caatctactg ggtactgtga tgatgttgac tctccctttt
    27601 cttggattac agttgtttgg tggaaatctc attgaaaaaa gtgcactttt gggtggtaca
    27661 ctccaatctg ttggtcaagt agtcgctggg gcaagcttac ttgacaattc tgttgtcgaa
    27721 ttcgccatgc tatttaagat tctacgtatt atgatgctcg ttgttgttgt ctatctgttt
    27781 gaaaaattca tgcacaagaa acaaccagct ctgtttgaaa cgccaactga tacgcagaaa
    27841 aaacgaaaat taccgcttcc ttggtatgta ttagggtttg tgatcttttg tttggtcaac
    27901 agcttgtttt ctttacctgt agttattgac caatcggcac attttatcag cagctggttt
    27961 gagatcactg ctttagcggc aattggtctg cgtttagact ttgcaaaatt catgaaagaa
    28021 ggtacacgct tcttatctta tggattagct gtcgggcttc tccaaacagt gatggcttta
    28081 ctatttattt ggctgatcaa agtttagaat gaacatgaaa aaacagttgt gattctcgca
    28141 tggaacaatg tccgaatcac aactgttttt aattttgcag atatccttct aacaacaaca
    28201 attggcgttt gatttcaacc ccatctattg cgtttcccat atatcctgtc agttttccat
    28261 tttgcccgat cactcgatga caaggaataa cgattggcaa tggattggtt cgatttgcct
    28321 gcccaatcgc tcgcacagct ttcggactat caacagcaac ggctacttct ttatacgttc
    28381 ggatttctcc ataaggaatg gtcgacaaag ctttccagac attttgctga aaaggcgtac
    28441 ctctctttat agataaagga acatcaaatt cttttctttt tcccgcaaaa tattcttcaa
    28501 actgttcttg tgtgcgcgtt aaaattcgct gattcgctga ttcgctttct gaaattggct
    28561 gaaaagatac agcagtcaat ccggattcat ctgcatctaa ccataaaaag ccgataggtg
    28621 tgtgtatttt cattttgttt gctcctagtc aatagactgg aacttcctcc tttttctcta
    28681 tccaaaacta cttgccaact aataaaaatt gttcttaaaa gtttgataaa ccgaggaaac
    28741 atggtaaact aaatacgtta gtttacaaaa agaatacctg ttcttttacg taaaatcaaa
    28801 ttttaaaggt gttatttaag gtttattaaa ttttgaatgt aaaccatata taaacatacg
    28861 attgaaagga tagaaacgat gaaagtatca attgttgtcc catgttttaa tgaagaaaaa
    28921 actgttcctc ttttttttga tgaggttgaa aaattcaaag gtgcccatga gttcgaatat
    28981 ttgtttattg acgacggatc aaaagacggt acgttagcag caatcaagaa gctagcctca
    29041 gcttatcctt atgtccgctt tgtctcattt tccagaaatt ttgggaaaga agcggctctg
    29101 tacgctggat tgcaagcttc tacaggagat ttagtgaccg tgatggatgt tgatctgcaa
    29161 gatccgcccg aactgcttcc tgagatgatc aaccggatca ctacttctga tatcgattgt
    29221 gtcggcaccc ggcgttcgac tcgtgaaggc gagcctgcga tacgcagttt ctttgcgaaa
    29281 aaattctacc agttgatcaa taaaatcagc gatacagaaa tggtcgatgg cgctcgtgat
    29341 ttccgcttga tgactcgtca aatggtggat gccgtcctag aattaacaga atacaaccga
    29401 ttttcaaaag gattatttag ctgggtcgga tttaaaacag aatatatttc ttatgaaaac
    29461 cgcgaacgtg tggctggcga aacatcttgg tccttctgga aattattcaa ctactcgatt
    29521 gatggtatcg tgaacttctc ggatgcaccg ttaacgattg cttcatttat cggcgctttg
    29581 tcttgtgtcg gttctggtat tgcaattttg ttcattattt tgcgggcatt gttgtttggt
    29641 gatcctacat caggatggcc ttccatggtc tcgatcttcc tgttcattgg tggaatccaa
    29701 ttgttatgtc ttggaatcat cgggaaatat attgggaaaa tcttcttaga aacgaaacag
    29761 cgtcctgttt atatcataag agaaacagaa aaagtgaagc caaatgaatt gaagcctcac
    29821 caataatata cgtcaaatga agtaaacatt tttttaaatg aaaaaggact gtgacaaaag
    29881 tcttgtcaca gtcctttttt ccgaataaat ggtgttccag aagtagcttc ttcggaaata
    29941 agccgaaatt tcacaaaaat ttgagaagca attttcgtaa attccttctt atttcttgaa
    30001 gctgaccact tctatcacaa cctctttcat atcttattac ttcttcattg ctgcttttag
    30061 tgctgctgct aatgggcttt cttctggttc ttctgcttgt gcatattttt tcagcaagcg
    30121 tcgttcttca tgtttggtca ttttcttctt ctgctctttt ttatcaagca atttttctgt
    30181 cgttccatcg tatttacaac ggaaataagc accgttttta ccttcgatga tttccatttt
    30241 ccggtgacat tgcgggcatc gatgattaga gacttttgga tcttttcttc tgcggtagtt
    30301 gcaatctgaa ttggtgcaga catagatttt gccgtcacgt gtgtttttct cgcgcagatt
    30361 ggccccacat tctgggcatt tcttttgggt aatcgagaaa tcttgatatt cttgtttgct
    30421 tgatttgatc tcattcacca agcgttttgt ttctttttcg attccattca agaaggttcc
    30481 tgcttgtttc tttcctgcag caatagcttc aaggtctttt tcccagcttt ctgtcaaatc
    30541 tggtgttact aaagagggat ttaccaatac taataattgc ttacctttag gagatacttg
    30601 cagtccttga ggggtacgtt ccatcagttc agatttgatt agtttctcga taatctctgc
    30661 acgcgtagct ggggttccca gactgtattt ttccatttga ccaagcaagc ttgcttctga
    30721 caatggttta ggcggtgcag atagttcttt tttgatggcg aaatcgggat tgattctcat
    30781 tcctttttcc catttgactg tttccgtctc agtttcagtt tcgcctttcc atcctgcttg
    30841 gacgacacga ttttgccgaa aaatgaatcg ttctttacca aattcaaccg taacttttgt
    30901 ttggctgact ttatggggtt gagcaaacag tcctaaaaaa cgagagacaa tcatttgata
    30961 gatttttcgc tcttcattac ttaatttttc ataacgtgct ctgttttcag ttggcaaaag
    31021 tgcatggtga tcggtcactt tactgtcttg gaatactttt gtctgttgga cgatggctcc
    31081 gtttttcaaa tactgcttga cctcaggagc aaagtcgctg actgcttgca atcgttcttt
    31141 catcgtactt ttcatgtcat ttgtcagata tttgctgtct gtacgcggat aagtaacgat
    31201 cttatgggtc tcatacaaac tttgtacaag acttaatgtt ttctttgcag aatagccata
    31261 gcgttgattg gcttctcttt ggatctctgt taaatcataa ggcaatggcg cagattccgt
    31321 ttttaatttt tcttggactt ctgtgacagt tcctttgctt gtactgatca attgaacaag
    31381 tttttgtgct tcttcttgtg tttttaaagc aaattgattt ttttgaagca ttttggcttg
    31441 ttcttttcca gcttgcaacg tgatcgtgaa atacgtttgt ggacggaact gctcgatttt
    31501 cttttcttgg tctctcacta atgctagtgt cggtgtctgc acacggcctg ctgataaatt
    31561 atccgcgtac ttcacagtta aggctctggt cacattcaat cctaccagcc agtccgcttt
    31621 tgcccgggca agagcagatt catacaatgc atcatattct ttcgcaggtc ttagttgctt
    31681 gaatccagtt ttgattgctt tatctgtttg agaagagatc cataaccgct tcactggttt
    31741 attgaaatgc acatactcta agatccagcg agcaacaagt tccccttctc ttccggcatc
    31801 tgtcgcaatg actgcttctg agacatcttt tcgctgagcc agctgcttga ttgcttttaa
    31861 ttgatgtcct gttttaggaa gtggtttgat tcctagtttt ttagggatca ttggcaacgt
    31921 gtccatttgc cagctctgcc attccttatt cagatcttcc ggcattttca atcctaataa
    31981 atgaccaagg gcccaagtaa cgatcacctt gggtccttca taataatttt tgtgcttttg
    32041 attagcacca agcaccttgc ttaggtcttt cgcaacgctt ggtttttccg ctagaattag
    32101 ttgtttcata aaattccttt ctgctttcta ctgtgatggg ctgatgattt ttcaacaacg
    32161 caagtccctt gtattgctgt aaatcatcgt cacactcttc acaccagcgc tcatctccgt
    32221 cattccaaaa ggcgctgaga aagttacttt ttgcattgat atattcataa ttttgatgga
    32281 tttcgttcca ttgtttttcg tacgcttgtc gtgcttcttc gaaagactcg aatgtttctt
    32341 cttcttcaat atcttcttcc cagtcttcaa aaaaccacca aggctcattg tccccgaaca
    32401 tggtaattac ttgatacata ctcgtgctcc ttctttcagc ttttctagac tcatcttagt
    32461 cacttttcaa gaaagttgca agaattttct cttataaaag ggtcatttaa tgaacatctt
    32521 aaaattgtta caaatgaatc tgattgttta aggcaaagta gcgataaagt tattgatcat
    32581 ccaaaaatag ctgtcttctg gatcgattgt tggttctttt gtaaagtatc ctaaaaaacg
    32641 taaggaaaga taaccgtgga tcatactacg aagttccctg cttcgatgaa ctttttcttc
    32701 tttcgttaat tgaaaagcct caaatatctg caaaatgatc tgattcgttt catggattcc
    32761 atctaataaa acagcttcat tggtatgcgg tacactgatc agtaactcat acactgcttg
    32821 atttgaaaaa gcaaaggatc gataagtttc tgcatagatc tgcagtgctt cctgaccact
    32881 ttttcccaca agagcccgtc gcagctggtc attaagttcc tgcagaagtt tcgctgttag
    32941 cgctgttttg acatcacgaa tatttttgaa atggttatac agcgagggag ccttgatatc
    33001 caagcgtttg gctaaatgct gaaaggttat ttgctgaaca tccatctctt ctgctagttc
    33061 tcgaaagcag tcgatgattt tctcttgaga cagatttctt tttttcattt ccatgtttcc
    33121 tctcataaaa taaatccttc actctttcag tttaccacga aaaagaaaga gaaaaaagag
    33181 actttcattg ataaactaca tattgtagtt tataataaag agctgtagat gaaaattttc
    33241 agaaagaagg agtctaattg gctgcaagaa taaaggaaaa attatttagg aaaagagaaa
    33301 cttgggaaca aaacttgttt gtcttatggt ttggaacatt tatggctggt atcggattta
    33361 gtttagtcat gccttttatg tcactttaca tagatacgtt aggtaattat agtacgtcac
    33421 aattgaactt ttggagcgga ttgacttttt catctacttt cttggtgact acgcttatct
    33481 ctccttggtg gggaaaatta gccgaccaaa aaggaagaaa attgatgctg ttgcgtgctt
    33541 cattaggaat ggcaatcgtc atttctttga tgggttgcgt gactagtgtg tatcaattag
    33601 tcgcattgcg tctgcttcaa gggatttttt ctggttatat cagtaatgcc actgcccttg
    33661 tcgcaactgg gacgccaaaa gaaaaaagtg gtcaagttct tggaacctta gcaactggtt
    33721 ctgttacagg aacattactt ggaccgcttc ttggcgggat ctctgcttca gcgtttggct
    33781 atcgccctac ctttttcatt acagggatca tcttattttt cgtcttcttg ttgagtctgt
    33841 ttttcgtcca tgaaaaattt gtcccagtga aaaaagaaaa catggtttct gccaaacaga
    33901 ttttcaaaga cttgaaatat ccacacgtcg tcatcggtat gttcgtcaca acgatgatca
    33961 tccaagcatc caacaattcc attagtccaa tcatcagtct gtacattcgc caattgctgc
    34021 atggacatgg gaatgttacg ttgatcagcg gaatcattgc ttcgatacct gggattgcca
    34081 ctttgatagc cgctccaaga tttggtcgct taggtgacaa gattgggagt gaaagaatac
    34141 ttgcgattgg tttgggtttt gcgattctgg tttatatccc aatggcattc gtcacgaatg
    34201 tttggcaatt agctgcctta cgttttttga ttggtatctc tgatgcttgt ctgctccctg
    34261 ctgtccaagc attgatcaca aaatattcgc ctcatcaagc tgctggacgg atcttcagtt
    34321 ataaccaatc tttccaagca actggtaacg tagtagggcc tatgatcggc tccagtgttt
    34381 ccagtgcatt tggttatcgt ggcgtctttc tttcgacttc tcttcttgtt ttggtcaact
    34441 tcttgcttgt acgacacaat acacaagaga tccatcagca agaaactgca gaagaaaaag
    34501 cttcaggagt ctccatagct tcagggcact ctccttctca tagacaataa gcgtaaatga
    34561 aaaacactgc ttgaacagtt gtcacagact gtccttgcag tgtttttgtt taggcctgtt
    34621 ttttcaagaa ctcagataag aggaataatc ccttttccaa ggtttctttt ttacaacagt
    34681 aacctagtcg ggcatgcttc ggtaaatcaa aggcacttcc tggtactaat agtactcctg
    34741 tttcttctaa taaattgata caaaatgtct ggtcatcttc ttcgatggct aatttaatga
    34801 aagaagtaga gacgtaattg ggagcgacaa gttcaacttt cggttcattg gctacccatt
    34861 gttttaaaat cacaaggttc tctgtaatga tctttttgtt tcgcgccaat attttttctt
    34921 tattcttcaa tgcatgtaca gcaagatcat ctgacaggac tccgccgcaa atcatcgtgt
    34981 agtctcgata ctttcgaaaa acttctgcca actcaggtcc agtagctgtc cagccaatac
    35041 gaatacctgg aatggagtag gttttggata gggaattggt tgctatacct ttttcataga
    35101 catctacgat cgacaagaat tcacctttat ccgttaaagg cgcatatact tcatctatca
    35161 atacatatgc atctactgta cgagcaattt ctgcgatttt ttctaaagtt ttccgatcta
    35221 gcaatgtgcc tgtaggattg tttgcactat tcaaacagat gatttttgtt tcaggtttga
    35281 ctaaggcttc tagctgttct aaatcaaact gccaatcttc ttcttccttc aaatgaacaa
    35341 agtcaacagc ggcacctaaa gatttgggga tgtcatataa ttgctgataa gtaggaagca
    35401 tcgaaacaac atggtctcct gcttccacta acgcgtatag agctaaaaga ttagcaccag
    35461 tcgctccatt cgtttgtaag atgttttccg gatcgacggt ttgataaaga gaagcgactt
    35521 cttgtttgaa aacatctgat ccttcgatcc agccatagtc caatggttcg tttttgcgtt
    35581 tttcgaaaaa tttacttacg ctagtcccat ctaagccaac gagttcgtct aatgtcaatg
    35641 cttcgatcga gctttgtgca atatcatata ccgctttctt ttcccattta tttagccatt
    35701 cttctacacc gaaatttgcg attttcatgt ttctttcccc cttatatctt gatccagcct
    35761 acagcaagca acccgattga aagcagtgcg gccacacaaa tcagcccaat cattactttt
    35821 tcttttcccg taatttgatg tttggtttca cgacaagcga tccagtagaa gcaaaaacca
    35881 ggaagatagg caatactaca taaaaggaca taagaaaatc ctgctaaaat gatgcccatc
    35941 aattcaaaaa ctacagcaat cccaccgatc actacttgtt ttttgattcc ttcttttaaa
    36001 gaaaactgga cttgatagat cccgacaagt agataacaaa tcaaaattgc cgctgtacat
    36061 aaagaatagg caaattgata ggcataatca gtaactaaga aagtcaataa gaatagatta
    36121 gtcaagattg cagtaacaac taacgaataa gttggggcat tttttttatt cgtttttccc
    36181 caacctttcg gcaacagacc gtctcgagcc atcaacatcg ttgtttctgc tgggagcatc
    36241 gtccaagaca accaagaacc aatgatcgaa ataatcaagc cgatattgat cagcgctgct
    36301 ccccaatttc ccacgattcc ttttaaaata tttgccatag caggttgtga aatagttgct
    36361 aactcttctt gagataagac gccgtatggc aagatcgaag caaggatata gataaacaat
    36421 aaacaaagca gaccaatgat cgatgcttgc tgggcttctg aacgtttctt cgcgcggttg
    36481 gctaaaacac ttgcgccttc gatccctaca aagacccaca tcataaccat caaacaacct
    36541 ttaatctgca accagatcgt tccttgctgc cctgttccat tcactagatt atcagatacg
    36601 ttaccccaaa aatcagcagt gaatatattc actttaaatg cgataaatac aaatattaaa
    36661 aataggaata atggcactaa tttacagatc gtcacgattg tattgatgac gctcgctcct
    36721 tcaactccat tgtttactaa taaagtcaga ccccaaataa aaatacttgc aaataaaata
    36781 gaaggaacat tttgtccacc tttgaatatc gggaaaaatt ctcccatggc gctcatcagc
    36841 atcgttgcaa aagcaacatt tcccagccac gcagacaacc agtaacccca accactgatg
    36901 aagccaccta atttaccaaa tgaagcttcc gcgtaaccga aaataccacc atctagatct
    36961 ggacgctttt ctcctaaatg attcagcgat aataccaaag ctaaaatacc aatcccaacg
    37021 attatccatg aaaggatcgc tggccctgga gctgcagaac tagccagatc acttgtgatc
    37081 ccaaacacac cgcttccgat tgacgaactg acaaccagag caaccagtcc ccatttgcta
    37141 atacccgtcg atttcttttc catttccatc accctcactt ataaaattga acaaatcact
    37201 tgcaaaagat tcccttctat tttgcaactg ctcttgctta acaaaaagca actttattca
    37261 tattattgga tattatgaac tttttacaca agtatttcaa gtataaaatg aataaaaatt
    37321 aattttattg caaaaaaaca gctatgctat ccaaaagaaa aggtgtttct tttgttagcc
    37381 atagctgttt tgattcattt aatatcgctt aaacgtattg taaaactttt gtttcttgat
    37441 atgcgtggtc gatcaaacca ccacccagac attccattcc atcataaaat acaactgctt
    37501 gtccaggagt gattgcacgt acaggttcgt cgaatacgac ttctgcacga ttatcatcca
    37561 ataagcgaac tgtcacagga acgtcttgct gacgataacg gaatttcgct gtacacttga
    37621 attcttttgg cattggttca ttcgtcgtaa agtggatttc acttgcatcc aagcttgtgg
    37681 catacaatgc aggatgatgg aacccttgcc ccacatataa tgtgtttgtc gctagatctt
    37741 ttcctacaac aaaccagggt tcttgcgaat ctcctccgcc accgatccct agtccttgac
    37801 gttgaccaat cgtataatac atcaagccag catgttgtcc tttgacttca ccatcaagag
    37861 tgaccatatt tccttttttt gctggcagat agttgctcaa aaattgtttg aagttctttt
    37921 caccaataaa gcagattccc gttgaatctt ttttcttagc agtcgcaagg cctgcgcgtt
    37981 cagcaattgc ccgtacttct gatttttcca tgccgcctag agggaacatc gtttttgaaa
    38041 gctgttcttg tgataattgg ctaaggaagt aagtttgatc tttattattg tctactccac
    38101 gaagcatgtg gaccacgccg ttttcatcgc gagtgacttg cgcataatgt ccagtagcta
    38161 cataatcggc gccaagatcc attgcataat ccaagaatgc tttgaatttg atttctttgt
    38221 tgcacatcac gtctgggtta ggtgtacgtc ctgcgcggta ttcggctagg aaatattcaa
    38281 atacacgatc ccaatattct ttttcaaaat tcacagagta ataaggaatc ccgatttgag
    38341 cagctacttt cgctacatcc ttataatctt ccgtggccgt gcatacaccg ttttcgtccg
    38401 tgtcatccca atttttcatg aatattccga tcacgtcgta tccttgttcc tttaacaaaa
    38461 gtgctgttac agatgagtcg acaccgccgc tcatccctac gacaacgcgt gttttgctgt
    38521 tgtctgtcat gatatcacca tcatttcaat tagattctga aacatctacg agttgaaggt
    38581 cgcaactttt cagtatttta cattatacgt catatttctg aaaatttcat cccttaatta
    38641 tcaagtcgta aaaatactgt tctactggac ctattcagta cacaaacatg atagtcaacc
    38701 aaaaaatcac tcatcttttg agcattcgat ataaaaaatt ggcatactca taaaaagggc
    38761 cagcctttcg gcaataagga ataattttat aaattgtgaa aaactatttt tcaaaattgc
    38821 ttcttatcgc ttaaagctgc acgtctcatt tacaaccttt tctttttaga tgttatgagt
    38881 tgctcagata agtgattttg tttactctaa gaaaaaaggg aggcaaaaga tacatgaatt
    38941 actttatcag tgatatgcac tttttccatg aacacttatt aggaaaaaac gactttgctc
    39001 cgcggctctt tgcaaatgtg gatgaaatga accaacagtt gatcactagc tggaatgcag
    39061 taataaaaga aaccgaccat gtttatcatc taggcgacct tgctatgcat ccgcaatatg
    39121 aaaaagcaaa tgcagaaatt ttggaactgg tcactcaact gcaaggaaca atccacttga
    39181 tcaaagggaa ccatgacagt cgcgcttttt tccgttattt agaaaaaaat gatcctaggc
    39241 ttactgacgg aagtcccaaa ttttattttt atgatgtagg tgccatcgtt aaattcgacc
    39301 atcaacaata ttacttgact cattatccga tgttgctcgg gcctaacgac actatccgca
    39361 atcttcatgg acatatccat cattacagcg tacctatcga gaacgatgtc aatgtaggcg
    39421 tagacgcacc ggaaagagaa ctcttaaagg aaaaactacc atttggcact ccgttatctg
    39481 agcaacaaat caaagaaatc tatgaagcaa agaggaagta cgataggtcg tgaaaaaact
    39541 gccctatatc aagtattaaa caaataaaga taattactca tatttttcat ttgagtaggc
    39601 ttattgccac aggaacatta ggatcagaaa tggagttgta acaagacttc tgtcacaact
    39661 ccattccata ctattcgtct ttttgctcat ggtgttcttt taccagtttt ttctgtaatt
    39721 ctttatcata atttcgggca gctgacgtta aaaataaaac gattccgcat aataaaatcc
    39781 cgattccgga aaacaagaac attttttcta cccctaaacg atcagctaat ggtcctgcaa
    39841 ataataatcc aattggacct gccaggttca tcaaagagtt gaagttccct aagacacgac
    39901 ctaaaacatt cgattcataa ctctgctgga tcattgccat cagcagtgta ttgaaatatg
    39961 gcgttgcaca acctgctcct gcattcaaga taagaaagta caagaaccct tgactatcgt
    40021 ttggaaccaa tccgcttgca ccgatcgtca ggcccataat gatgtaggct ataataatag
    40081 gtttcattcg gtctttccat gttcctataa aactgatcag tgcaccgcct aagagcattc
    40141 cgactgcgta gactacttcc actgctcccg cctgtccaac ggaaccacca aagtaatcta
    40201 gcgtcatcaa tggatacaga ctgattgctg gcatgaacaa cagcatcaca aatgcaccat
    40261 tgatcgttat gtaccataac cctttattat ccatcaattg ctgcagccca aattttgcat
    40321 ctttaaaaat agtaagcgga acttccaata tttcaggaga aacttttggg atcttcacaa
    40381 aaatcaataa gccgacacca aaaactgccc ccaatacatc taataaaata aggtaattga
    40441 caggaacgac tgaaaacaaa gccgcaccta gagctggcgc aatgatgaaa ttcgctgatt
    40501 ggaccattcc taactgtcca ttcgtccttg ttatgtgaga agatggaacg attgtcggca
    40561 taatcgactg gatcgttggc atttggaatg tttgtgcgac cgaacgcata aacaaagaca
    40621 caaaaactag ccaaatcggg aaggattctg aaatcgttcc gactactgct aaaataagcg
    40681 cgaaaatcgc tacaataata tccgtgacaa tcaaaagagc ttttttatcc cagcgatcca
    40741 ctagcggtcc tacaaatggg cttagtaaaa ccatgggaat cattcctagt aaagtagcaa
    40801 aactcaaaat tgtcgccgaa ccggtttctc ttgtcaaata ccagatgatc gcatattgga
    40861 cgaccatact agtgattcct gacaaaaact gtcccgataa aaagaacaaa taatttctct
    40921 tccaattcgt taaaacgacc gactgttcat tttccataaa catccctctt ttctttttca
    40981 ttttgtatag cgtttgcaca acaatcatta tacgggattc ttttttcaaa aaataccttt
    41041 ttccctaaat aacaatcgtt tcaatttaaa tttctttact tagaaacaat aaatcagcaa
    41101 aatattaaaa ataacaacat gtgttaaatt taaaaataaa aaagacaact aatttgcgtc
    41161 gtccttacaa agttagtcat ctaacaatag gccgtttcaa aactagttgt ctttttatat
    41221 ccacagatca ttcgactttt tcgaataacc cacggctaat catcccatcc atcagaaaat
    41281 aaaatttatc ttggctcatt ttctgttttg gatctttgaa aatattgact gctttcaatc
    41341 catttgctgt agtgatcgac attttcaatg tttgaatatc ttttgataca gtgattttta
    41401 atttgaatcc ttctttgctt tgcggcgtgg catctaatgg tcggatcaat tgataattgc
    41461 ctccgtttgt ttctgtaaat ccattatcgc gcaatgtata tctttttgca tcaggatgca
    41521 aacgatagct aattggtgcg cccagtaccg ttgctgttgt ttcaaatgcc atgattttca
    41581 cctcgataaa attagtttct ctttattata aaagtttatc ctgattttta ctaggttttt
    41641 cagttaagtt ccctaaaaaa tgaaggcgtt ctctcagaca tctgttcata taagaatgac
    41701 ttcactagtt attttttgac agcacgaact aattgatcaa ggaaatactg gatgtcgtct
    41761 tcggtatttc ccaaaccaaa gctgatacgg atggattctt ttagtatcgg tgtatcttct
    41821 ccatacattg cttctaatac gtgtgaaggc tcgatatttc ctgctgtaca agctgaacca
    41881 gtagaaatag cgaccccatt aagatcaagc ttcatcagta gcaaatcatt tgcttcgcca
    41941 attaagcgaa gattcaacac atgagggagt ttattcgtta aatcaccatt tacttgataa
    42001 gggatttcgt ttgcttctaa tgtatcaaga atcaattgct ggaatccttt atatttgttg
    42061 ttacgtgctt cacgttcttc aggtgacagc agttcaactg cttttgccat accccagatc
    42121 cctgctaaat tttctgtacc tgcacgccgc ttttcttcct gctccccgcc taaaagcaat
    42181 gcagggatat ttactccgtc tcgtttatat aagaaaccga cgccttttgg cccattgatt
    42241 ttatgagcag agatacttaa taaatcgatt cctaattctt ctggatggat cgtttggttt
    42301 ccgtacgctt gtaccgcatc tgtatggaaa taagctggat gatccgctaa aagttcaccg
    42361 atttctttga ttggcatcaa atttccgatt tcattgttcc cgtacatcac agagaccaag
    42421 atcgtatctt ctcgtaacgc ttttttgacc tcttcgatcg acagattccc tttttcatct
    42481 acaggcagat atgtaacgtc aaaccccttt gtctctaaat atttcatggt attaagaaca
    42541 gcaggatgtt cgatagctgt agtgattaga tgtctgcctt ctttttgacg cgagaacgct
    42601 gtttctaaga tagctgtatt atccccttct gttcccccac tgttaaagat gatctcgtga
    42661 ggttttgctt gcagactgtc tgcaatgatt tgtcttgctg tttccaattt ttcatgcgcg
    42721 tggcgaccaa atccatgtat gcttgaagga tttccaaacg tgtcttgcat gattgccgtc
    42781 atcgcttcaa ttacttgtgg atgcatgggg gtagttgccg catgatccag ataaatagtt
    42841 ttcacttcat tcatcccttc caaattattg ctaggcacat tctagcataa aatagcgaac
    42901 aaaccaaaga agagctcatt tttgtctaga ggacgtttca tgggcataga aaaaaggagc
    42961 tgtgacaaaa gtcttgtcgc agctccttga agctgctcac ttctgtcaca acttctttcc
    43021 ctcttttttt tgtttattcg aattcttttt cttccagacg gaataacgga ctcatcggtg
    43081 tattttcatg gatgcgtttg accgcttcac ccattaattc tgaacatgta acgattgtta
    43141 agttttctgg atgacgattt tcttctgtga aaacagaatc agtgatacaa atatctttga
    43201 ttggtgcatt gtctaaaata cttttcgcat gatcggacaa taatccatgt gacgcacagg
    43261 catatacttc ttttgcgccg ttttctttta atacatttgc tgctcgtgca agcgttgctc
    43321 ctgtgttcaa gatatcatct accatgatac atgtctttcc ttgaacatca ccgatcacat
    43381 aaccaccctc agttgaagca tcatctgcat gatctacgat ggctaatgtg ctgttcaaat
    43441 attctgaaag actacgtgca cgctgaacac cgctgttttt tggcgaaaca actacgatgt
    43501 catctcccgt cagacctaat tgacggtaat aatgagcaaa caacggcatc gtaaataaat
    43561 tatctacagg aatatcaaag aatccttgta cttgaaccgt gtgcagatct aaagtcagta
    43621 ctcgagttgc ccctgcttct tcgatcaagt tagcgatcaa tttcgcagtg atcggttcat
    43681 gaggtttcgc cgtgcggtct tgcctagcat acccatagta aggcaatacg acattgatcg
    43741 ttttcgcact tgctcgcttc attgcatcga tcatgatcag tagttccata tagtaatcat
    43801 tgacaggtgc attcgttgat tgaacgatat acacatgatc ccctcgaata ctttcttcga
    43861 tattgatgga aatctcgcca tcactaaatt gcttcacgac gcttttacct aattctgttc
    43921 cgaacacttt cgcgattttt tcagctaatg gacggttgcc attcaaacta aaaatcttca
    43981 acgtgtcatc ctgatactta ttactcatgt agtcctcccc aaaacttctc tattcttcga
    44041 tagtttaaca tatttttcca agattttctg ttaatttcag caaattctta aggaagtgaa
    44101 actgttccgt tactccaact ggcaggaatg actttatgat aatcgcccca gttgtcgtgt
    44161 actttgtaat aacgttctcc tgtttcagtt tcaaaataag cgtacgctgt cacccaatga
    44221 ttgccatatg tactgccaag tactttcaaa ataccaatca tcacaggttt gccttcacgt
    44281 atacgttttg tagctcgctg ccatgaacct agaagagttg ctcgtgcacg ctcatgattg
    44341 ccattcttct ttaaaaaact agaaatccct gtactaacct gaaaaggaat cgtaggaagt
    44401 cctagtggtt ggatctggct acgcaatgcc ttcgtcaaaa ccaacgaatc agccgtattt
    44461 ttcttgcgaa tctcatttgg aagcatccac cccttacgat agtcttgata ataggcaagg
    44521 agaactgctg ccgcgtaagt accacaaaga tagcctgagg gggtagccca tttcttatac
    44581 ctcaaaaaac gttcttctgg caatcccacc cagcaatttg cgagttcctt tcctgacctt
    44641 ttttcttcga tcaaaacggg aatatcttct tttctgttga tccatctaga taactcgatt
    44701 ggctcttcat tgatcagctt ccatttttta caagaaagac cctcttgata agtatatttt
    44761 gctggagaat attctaccgg atgtcctgat tgatcgataa tcacataact ttgatcttca
    44821 aaaaccagag ctaaaaaaag caatttactt tttcttgact gcagctgctg agtgctggct
    44881 aattttttaa tttttttatc tactttgaaa tataaaggtt tatccactac ttgattcagt
    44941 tgggatcgcc tccttttttt cattataagt gaaggattga aaaaaacaaa tcagtttgat
    45001 tgttcgaatt ttcaattttt tatgttctat ttgttaattc cttcattttg taagataatg
    45061 ggcacacgaa acaaaaaagg agcgatcgat gaatgaacaa agaacgattg aaacaagatt
    45121 tctatgaagc agtcaatgaa gaatggcaaa aaacagcaaa aatccctgca gataaaccag
    45181 ctacaggcgg tttccaagat ttagttgacg ggatcgacca acttttgatg ggagaaacag
    45241 acgatctgct tgcccatcca gaaaaagtgt cttcagaaaa aatgaaacat ttccttgcat
    45301 attatcaact ggcaaacgat tatgaccgaa gaaatgagtt gcatgctcaa ccgcttcaac
    45361 ctataatcga aaaagttgaa tcattgcagt ctttcgacga attgaataag caatttccag
    45421 aatggctgtt ggatacatta ccattgccat ttaatctgga tgtagatgca gatatgaaga
    45481 atgcgcaaac gaacgccttc tttgcttatc cgccttcttt attccttcca gataagacgt
    45541 attatgcatc agaccatccc aacggtgcac aactaatagg cgttttcttt gatatggctg
    45601 ttcagttatt agagcttgcc ggcaaagaaa aaagtcaggc agaagcaatc acggaacaag
    45661 cagtgcaatt tgataaattg attgctcctc atgtaaaaag tgcagaagaa aacgcagatt
    45721 acagcaaaat gtataatccg caatcttttg atacatttat taaatacaca gataaactgg
    45781 acttgaaaaa acttgtcacg ggtttgattg ggacaactcc agataaagtg atcgtaactg
    45841 atccagtgta cttcgatcat ttgaatgaca tcctgacaga agctcatttt ccgttattca
    45901 aaagctggat gatcattaaa acagtacgtt ctcttagtgg ttatctatca gaagaattcc
    45961 gccaagtcag cggaatctat tctcgcgtat tgtctggaac agacgaagca atgcctcaga
    46021 aaaaagcagc gtattacctt gcctctggac aattcgatca agtagttggc gattactacg
    46081 gaaaaaaata ttttggcgaa gctgctaaaa aagacgtaga acaaatggtg aaaaaaatga
    46141 tcgccgttta taaaaaacgt ctagaagaaa atgactggct tggggatgca acaaaagaaa
    46201 aagccgtcat aaaattaaat aacttaggta tccaagtagg ctaccccgat aagatcccag
    46261 cattattcga ccagttcaaa acagtacctg cagatcaggg tggtactttg ctttcaaata
    46321 ctcttgtttt cagcaaactc acattaaaag atcgtttcag caaatggaac aaaccagtgg
    46381 atcgttcaga atgggaaatg agtgctgaca cggtcaatgc ttattatcat ccatttcgga
    46441 atgtgatcgt ctttccggca gcgatccttc aagcaccatt ttacagtcta gaacaatcaa
    46501 gctctgctaa ttatggtgga atcggagctg ttatcgctca tgagatttcc catgcatttg
    46561 ataataacgg cgctttattt gacgaatatg gcaacttgaa caactggtgg acagaagaag
    46621 atcttacaca atttcaaaac aaagcacaag caatgatcga agaattcgat ggtctgcctt
    46681 ttgctgacgg aaaagtaaac ggaaaattaa ccgtttcgga aaatattgct gatgcaggcg
    46741 gtctaagctg tgcattggaa gcagcaaaaa cggaatcaga tctttctatc gaggaattct
    46801 ttgtcaattg ggcaacgatt tggcgtacaa aagcaaaaaa agaataccaa caacttttac
    46861 tgcaaatcga tgtccatgcc cctgctaaac tccgagcaaa cgtgcaacca aaaaaccttg
    46921 acgaattcta tgaaacattt ggtatcacgg aacaagacgc tatgtatcta gcgccagaaa
    46981 aaagagtgcg aatctggtaa gaggttgtgc cagaagtggt cagcttcaag aaataagaag
    47041 gaatttggga aaatcgcttc tcaaattttt gtgacatttc ggcttatttt tcgaagaagt
    47101 tacttctgga ataccatgta ttagaggttg tgaaaaagct gcttagtttc aagtagtaag
    47161 aaaaattttg tgaaaatggc tttccacatt tttgcataaa tttgacttac taccgagaaa
    47221 ctggcttttg aacaccgttt atcgagaggt tgtgaaatca gcgtcctgac ctgagtatta
    47281 gagaaaaaaa cggaaaaata gttcctcata ttttgccgtt tgttgagcta ataccgaggg
    47341 tcagctgatt gaacaccgtt tagtggagag attgtgaaaa agctgtcctg catcaagtaa
    47401 taagaacagc caatcaaaag cagcaaggag aacctcatct ataaaaagat agaaggaagt
    47461 gagacatcta ttggtctcat ttccttctat ttttactttc ctcagtcaat tgttttacat
    47521 cataaaagga gaaattccac ttattttttt cgctgtttca tgacataaac aactacaccg
    47581 attaacaaaa ttcctccagc taatgctagc aacgggttat taaattctcc cgtttttggg
    47641 agtccttgag tgccattttt ttcactttct tttgctgtcc tatccggatg agaaggtttt
    47701 ccatttggtt ttccatttgg tgattcattt cctggatttt ctctttctgg tttgtcattt
    47761 cccgggggca catcggcagt ttctcgcaca gtgatcgctt tttgctgggt aacagattct
    47821 gtatgagcag accatttttc cccatcaaat atttccgaac gataagtgac ttctagcgta
    47881 tattctcctt ttgaaggtgc tgaaaaaata gcggtatgat tagaaaattg agcacttgac
    47941 tgtgtttcaa cgatttggat cttttctggg aaataacgca tatcttcaaa gacaggcgtt
    48001 ccttgatttg gtgtgaaagt tgacacaaaa actgtaaaag gcttcagttc aatgatattt
    48061 ccttctgcat tctccgccac accatttgct tcttgtataa taatcggatt attttgttca
    48121 tttggttttg tctgatttgg ttcttgtacg attgcatact ctggatattc cgaagacggt
    48181 gaggtttctc cgtcaaaaat agcacctaca gataatggaa gaccatccac tctttccttt
    48241 tctgtttgac gattccccgg tttaatctgc atcagtccat gaacatggat acttccattt
    48301 tcatagcgcg taacaggctg ctgaccttct ttcgaacatg tatttagaga ctcgatccaa
    48361 tcttttgata tggtatgtcc aagagtattt tctgattgtt tctctcgttc attccaatag
    48421 tagttcaacg agtggtagat ttgatcttcg ttttgattca atgggcggat ctgctctctc
    48481 atctcaagat tctctgttcg gaaagataag ataccagaag catggtagtc tgtgtttcct
    48541 gctgaagagg tataaagagc cacattatat gaaccgttat taaaacttgt actgctattg
    48601 acgataatat ctgttccgct attggaatcg attcctttcg caagattttc gaaagacaaa
    48661 ctattgatca attcatgagg gcccgttaaa gaagaaccgc ccattttgaa tccattaccg
    48721 ttaccttctc cctcaattcc tggtacccag ccgtttcgat aagcaactga gtttttgatg
    48781 attacttttc cgatcgaacc tgtttcattt ttagcaaaaa ggtcccaacc gtcatctgca
    48841 ttatgatacg cgatacaacc gtcaaataca tttccttctc ctattgtcag tttggccgca
    48901 aatccatcgg catcttcaaa tcctggatcg gcattttcaa aagatgtaca gttcttgact
    48961 aagttatgcg cgggccatgc ttcgaaagga tcatttgagc taccgctgat ttggattcct
    49021 gtatttccat tccgataagc atgaatctct tcgatcaaat tatgatttcc agaaatctgt
    49081 aatccttttt gcatagctgc actatttgta atgtcaaacc ctcgtaaacc ccagtagtga
    49141 ctgaacagtg tcatcccatt tccagttcct ttaaaatcaa gtacaggacg cttgttttct
    49201 ggatttttct ctgcaatcaa ctgaatcggg ttttctcttg tcccgttaac gccttttgga
    49261 atcgtcaatc ctctttcgaa ggaataagtt ccaggcgcca tgacgattgt ctgcccagca
    49321 tatgcgtatc tcaatgcttg tgtcagagat aatggatttt gtctgcttcc gtttcctgca
    49381 tctgaccctt ctggtgttac ataaactgtc gaatatttag gtttacggta gtccactgta
    49441 tgaagaatct cttttgtttc ataactagtc atctctacgt attcttctgg cggatagttt
    49501 ttatctggcg taaaactgaa agtaaattcg ttcgttcctt ccatcagttt tgtctgataa
    49561 tcaaattccc gattcgcagt gatagccaag ttttttgcgt tcttaagcac ctctcctgtt
    49621 gctttatttt taattgtcaa taatccgtca gcatttgctc taaaggacat agtatgatct
    49681 tggtttcctg aatgattact agaggtcaca gtgtaaatcg gatcaatcaa gcgagtaggt
    49741 ctttcttgcc caggaggatc tgtcgcagga tctgagtaag caacttcgat tccttctacc
    49801 ttgatcgtca tattccttgc tgcagcaaat cctgcataaa taaccgattc atctgaagcg
    49861 tataattttt cccagtcata catgatgtca gaagccattt cttctcctgt ttcaggatcg
    49921 taataatatg cctctaaacc agtattcgtt tttttcatct ctacgtccag tttagtaatc
    49981 gagttcgtgg ccggaaacag attcccatga ccgtttccga atatattata agaacctgtt
    50041 tctttttcca agaaccctgc tgaagtctct aaaggtgttg tttccactga gacactccca
    50101 ggagctggcg cagcttgcgg atcttcagat gatattcctg tgattgcccg tgtccccaat
    50161 ccaagtcgca tcgtatattt gctgccgctc gtgttgacca cttcttgtct atccgagtcc
    50221 cagacatatt cgatccgact gcctagtatg gcaaatgaat ttgaataaaa tgcctgccca
    50281 aacaaatgat tttttggtac tgcgtctctt accattaaag caaatccttc ttgggcattc
    50341 gtataggtcc aagattctat ttcgatcgtc gcccgcatcc taaagttgat gtctttgggg
    50401 attgcttgat aataataggt cattccatct gatccgcttg actggaattt tccgccgtta
    50461 ttcgtggaag agagccgcac gccgtcttct aatggttcaa tggcatacct actagcactt
    50521 gtgctttctc cgaaaacaac ccctttccac tcttcatttg cttcttcaga ttgctttttt
    50581 gtcttttcat tttctgattc tttcatcata ggatcatttc cttcttccgt atccatatct
    50641 tcactagttc ttggtatttc ctccattgtt gacatccctt caatgttcac gtgtgcattt
    50701 tcttcgttca cagactgttg ttcgttagca gcaacttcaa cgacagaaat taaaaccggg
    50761 gtactgagca taaggagatt catcattagc gcactgtatt ttatacgttt ttttaacaag
    50821 tgtattcctc ccgtaacaaa ttagaaagcg tttacttaaa gtattaccta atttattttt
    50881 actgtcaata aaaaacaaaa ttataataag tgtattttat aaaaagaaaa aatataactt
    50941 aagttgttga taataaagag atttattaac gtaaaaagaa taagtttttt taaaataacg
    51001 tataaaaaag agcataaaac aaagtcgttt gttttatgct cttcttttat tattttgtgc
    51061 tttttatttt atcaaatcac tttgtttttt tataaaattt ctgcgcctag tgtggactca
    51121 aaatgtctca atgcccattc atgtccaacg ggatcgaaac ttgccacggc atctttgaaa
    51181 atatggagtt tgtatcctag attatacgca tcgactgctg tatgcaacac acagatatct
    51241 gtacatacgc cggtcaaata aatatctgtg atctggcgtt ctcgcaaacg gatgtctaga
    51301 tctgttccac taaaagcgga ataatgccgt ttgtctatcc aataaacatt ttcctcttgc
    51361 tcatagtctt ggtataaact ttttaaagag ccgtacaatt cccgtccacc cgttcctatc
    51421 acattatgcg gaggaaataa gcggttctcc ggatgaaagg aatcttttgg atcatgcgca
    51481 tcaatggcaa aaacgacaaa atccttttga tcaataaact tctttgtatg agcagtcagc
    51541 tttttttcaa ttacttgtcc tgctgtccca gtagtcagct ttccatcctc tgcaacaaaa
    51601 tcatatgtgt agtcaatcga gatcaatgcg ttcatcttag tcctccttat acgagatgtt
    51661 tgacaaattc gatcaccatt tctgctgatc gtttgcctgc gtcttcgata aattcgtcaa
    51721 agctttgtgt cgccgagtga tctgctgtgt cgctcattgc acgtacgatc aaaaatggga
    51781 tattgaactg acgagctgtt tgtccaacag cggctccttc catttcgcaa gctaatgctt
    51841 cagggaaatt cgttaagatt tctttgattt tatctggcga gtcgacaaat gtatcacctg
    51901 taacgatcaa tccttctttt gcgttcaaat tcgttgcttt tgctgcttta accatttcac
    51961 tgcgcaaata tgtgcttgct tcataatata gaggcattcc tggtaattgt cctgggttgt
    52021 agccaaatcc tgttgcatct gcatcaaaat aagctacttt gtctgatata acgatgtcac
    52081 ctacttgtaa gccttcaccg attccgccag ctgaacctgt attgatcacc atgttcacgc
    52141 cgtattgttg gatcaacaga cttgtggtaa tagatgctaa gacttttcct ataccggaac
    52201 gtacgacgat cacttcgtgg ttacctaatg aacctgaaat aaataaagcg cctgcgcgtt
    52261 cccatgataa tggttcgctt aggttctctc tcaaaatttt tacttcttct tccattgcgc
    52321 cgataatacc gattttcatc tttttaattc cttctttcta tataaatgcg attgctaaaa
    52381 aaaccacaca taacattagg ataacaataa taagagattt catcaaaaaa gagttccatt
    52441 tggtcgtctt ttcccgttcg ctgatccttg ttttcgtgat tggtttattc tttttgcttt
    52501 ctttacgata aaagctggca atcttttttt cttcttgctg ataagctgtt tctgcttttc
    52561 gctgtttttt taatgactcg cttgcttgtg cttgttgtcg cttgcgaagt tcgcttcgcg
    52621 taataagcgg tcctttggcc ataagccgat ccctctactt tcctttggtc aatagttccc
    52681 agtattgaat cgcataaatc gtctttgcat cacaaatcaa ctgatctttc atcgcttgtt
    52741 gcgcctcttc aagagttaga tgatacaact ccagtacttc gtcttcatct tgtgctaaag
    52801 gattctcgac cttctctacc ccttgtgcat gataaatatg aaggacttca tttgcaaaac
    52861 ctggtgaaag atacatcgaa gtaagatggc tcagcgactt cgcacgatag ccagtttctt
    52921 cttctaattc tctagctgct gtcatttcgg gattttgtcc ttctcctgga tcgatttttc
    52981 cagctggaat ctccaaaatc actttttcta aaggttttcg aaattgtttg acaagaagca
    53041 gacgatcttg ttcgtcaaaa gcaatgatcc cgacaccgcc aggatgaaat accagttctc
    53101 tcttcgaagt tcctccatct ggcaaacgaa cttcgtctac agcaacatca ataatttttc
    53161 cgctatagat ttctttgcga ctgattgttt tttcttcaaa ttgctcattg ttcagcatat
    53221 cttctcctgc tttctttgta atcataactg cttttttttc atttttcaat ttttctcaaa
    53281 aactccttat tagtttacca tagataaacc ttagattttc tctaaatata gaaaatcctt
    53341 ctttagtccg atactcttta tagtagtccg tatgctaaaa taagtatgta atcgaataac
    53401 gaaaagaatt caatactcaa cgataaatga catggagggt ttattatgat aaaacgaaat
    53461 tggccgtggc ttctagcatt ggtcttgcta tttctctttg tccgaaacaa tagtttttct
    53521 tttgttctag gacttttatt gataggtgta gttttagttt tgtggggact ctttggttcg
    53581 cgcaggaaaa agggaaaaca agaagaaatt cctgcactga ctgacgaact tgaaactcac
    53641 tatgaaaaaa gcggtatgac agcgaatgaa atttcatttt ttcgacaaac aatgaatcaa
    53701 acaaaaaatg agatcaatca attgcaaatg aatatgcagc agacagccaa acttaaagca
    53761 atcgatctcc gccatgatcc agtcaaagca gcgaaagctt tattcaaaga attggtgaaa
    53821 gaaccaaacc gactgcatga agcaagtcag tttctttata cgcatctgcc gaatctagtt
    53881 gatttgacaa ataagtataa tgagatcaat gaccatgaga tcaaaaacaa acagacctat
    53941 gaaaaactag aagaaagcgc gcagatcatc gaccagctgt cagctttaat cgcacaagat
    54001 tatcaaaaat tcgttgctga ggatctagat gatatcgacg tagagatatc tgttgcgaaa
    54061 cagagcttaa agcgtgataa taaatatgaa ccagaacaaa aggattaact cttttgttca
    54121 taaaagaaga ctcggaacat tcagatgatg tctggctgtt tcgagtactt tttctaaagt
    54181 agagacattc atgtaagaat cgagaacaga ttcaacaagg aggaattttt tatggatcat
    54241 aaaccgactg aaacaaaaga tgttacacca gttaacgata cacttgaaga tttattgaac
    54301 aacccgtttt caactccaac agatacgctg accacttcac aacaagcgga gattgatcag
    54361 ctccaagagc aacagacagc tgctcgttta attgacaaac taccggcgga acgccaagaa
    54421 caagctaaac agctagcagc aaaaatcgat gctaatgatg cacagtctgt catcagctac
    54481 ggatcggctg cccaagcaaa attaagtgaa ttctcacaat cgatgttgaa tcatgtgcaa
    54541 gcacaagata ttggtcctgt aggagattcc ttaactgaac tgatgtatcg tctccaagaa
    54601 gccaatcctg acgaactgcg tgccggagaa gggaacatct tccagcgtgt cttcgggaag
    54661 gtcaaacaat cgatctatga agtgacagca aaatatcaaa agattggtgc acaaattgac
    54721 aagatttcag tgaaattaga taaagaaaaa gacggtctgc taaaagataa tctgatgtta
    54781 gaacagcttt accagaaaaa caaagactac tttgatgcac tgaatattta tatcgctgct
    54841 ggagaattga aaatggaaga acttcaaaca acgatcattc cagaagcgat gaaaagagca
    54901 gaagaaactg gcgatcagat ggatgttcag attgccaatg attacacgca attcctagat
    54961 cgtctggata aacgtacgca tgatcttcgc ttagctagac agatcacgat ccagcaagca
    55021 ccacaaatcc gtttgatcca aaacacaaat caggccttgg ctgaaaagat ccaagcatct
    55081 atcgctacag ccattccgct gtggaaaaac caagtcgtga tcgcattgac cttgcttcgt
    55141 caaaaagatg cagtaactgc tcaacgccaa gtctctgaaa caacaaacga cttattgaag
    55201 aaaaattcag aaatgctgaa aatctcagcc atcgaaacag cgaaagaaaa tgaacgtgga
    55261 atcgtggata tcgagaccct tcaaaccact caaaatgatt tgatcgaaac aatccaagag
    55321 acattgcgta tccaaaaaga aggaaaagaa aaacgtcgtc atgcagaagt agagcttgga
    55381 cacatggaag aagatctgaa acaaaaactg ttggatttaa cccaatagat cacctttcgc
    55441 ttgttactaa aacaaacgcc caacaacagt ttattacaac tgttgatggg cgtttttctt
    55501 atctttcttc taacttctcc attggagtct atttctcatt catcttgctg tgtccatagc
    55561 catagccaaa ataaatgatc agtccaataa ccattacgat accgaacacg atccatgtca
    55621 cagtttgcag acgaagcatc aatacaatac aagtcaagat ggagacgatt ggcaatagcg
    55681 gaacgaatgg cactttgaat tctccagctt ttggtttgcc aaacattttt ctcaacttca
    55741 gtaagcctag actaacaagc atcaaatagg cgagcgccat gatattcgtt agttccgcta
    55801 atacattcaa tgggaaaaat ccggcaaaga atacagctgc cacaccagcg gcataagtcg
    55861 cttttttcgg tgtacgatgc ttttgatcga tttctgtcat aaacttagga agtaagccat
    55921 ccttgctgac agcaaacagt aaacgagcaa gtgaatacat catcgagatc gttaccgtca
    55981 gtagcgttaa aattgcccct acagcgatca ccgcgcccac tgttccatgt cctacatacc
    56041 tcattgcaaa agccactggg tcattgactc ctagttcagt atacggaacg attcctgtca
    56101 agatcagcgt cacgatgatg taaaggacag tagcaatcag tatcgaacca atgattcctc
    56161 ttggcacatc tttttgcggg tttttgactt cctcggctgc cattgcaacg gcatcaaatc
    56221 ccaagaaagc aaaaaacaca agagctgcac catctagcac accggaaaaa ccaaaaggca
    56281 tgaatggctg ccagttatca ggtttaacga aaaatattcc tacaatgata aacaacgcga
    56341 tgataccaaa tttgacatat accatggcat tattcaaacg taatgctttc ttggcttcaa
    56401 gcgacacgat gtaagtgacg aatatcacta cgagcaccgc aatcaagtca atgtatgtac
    56461 cattttccgg attgtacccg ccagttaatg cttgtggaag ttcggcccct aaacttttca
    56521 aaaaaccttg catatagcca gaccatccgg aagcaacaga ggaaaccgct agtaaaaatt
    56581 ccccgatcaa caaccaccct gtcagccagg cagcaaattc accaaataca acatacagat
    56641 aggcatatgg cccaccaatc actggcactc gcgaagcaaa ttctgcgaaa cttagtccag
    56701 acaaaatgac aacgattgca gctaagacaa atgaaagtga cagtgctgga ccagcatttt
    56761 gattggccgc aacccctgtc accacaaata ttcccgtacc gatgatcgca ccaattccaa
    56821 gcatgatcaa atcagacgtt tttagttctt ttttcatctc actcgtatga ttgagattga
    56881 tctctttctt acgaaacaaa tccattgaag ttcctcccca ttttaggttg gaaaacagcg
    56941 attaaactgt tttcatatac cctaaaagga taccacctaa aatgactaaa aggcaaccaa
    57001 caataacata aatgagctct tttttcgttt ttctttcgcc aaggatgaaa atcccaccta
    57061 aagtagagat aatgatcccc atttgtgaaa gtgagaagcc aacagctaaa ccaagtgatt
    57121 tgactgttag aagcatgcag atgtttccta agccccataa taatccacag atcatgtttt
    57181 tccacacaaa ctgatcgact ttaactttac ggaaagcaaa gaagcttgcg cctaagatca
    57241 ttccgatact ttgaggtaag ataattgaca tcgcatccaa attcgcccag ttgacgatga
    57301 tggtatatac accataacca atcgtagaga agatcaatgc tctaaaaccc ttaccaaaat
    57361 caagcatttt attatctgta tctatttttc cttcgtcatc ttgtcgggca gtcaaatacg
    57421 caccgcttac aagaagagct aaagcaataa taccgtatac ataatctttc gtttgtgtcc
    57481 attcatggaa gaaaacggct cccgcaatcg tattcaaaat taattgaaaa ccagtagaca
    57541 atggtagccc tacagaaaca cccatgtact tcattccatg gaactgtcca ttttgtccaa
    57601 cactccaagc taagccggat aaaaatccga tcaagaaaat ccaaggggtg attacaggac
    57661 taacaacgaa aaagacaact aaagaaaaca gaaatgcacc gatcgtcatt cctagtgttt
    57721 gttgattggc atcgccacca attttaccac ttactaaacc aatactaccc catgccaaca
    57781 tagggactaa tgctattaaa atttccataa ccaatctcct tttatttcac atgataagaa
    57841 acttatcagc gaaaacgtta acaacacaag cacttttttt cgtttctaac gattttctaa
    57901 cgtttttcat tataaaaatt taagattggg aaaaataaag tcattgttgt cccttttcct
    57961 tcagttgatt cagccgtcaa atggatacct aatttttcgg ccagattttt tgctaaataa
    58021 agtcctaatc ctgttgaatg tgttttgcta agtcgaccat ttctcccagt aaatccctta
    58081 tcaaagatcc gtttcaagtc ttccgctggg ataccgatcc ctgaatcttt aactgaaagg
    58141 ctgactcctt gcgcttcctt ttctatgctc acaatgatgt ttccgtgatc cggcgtatat
    58201 ttgatggcat tactaagcaa ttggttgaag ataaaagcga tccatttagc atcggtcaaa
    58261 acagtatgat cctcaccaac gatctcgtag cgaatatttt tttggataaa ataatttgcc
    58321 tgactgcgta tcacaggctg aatgattcct tttagtccat attcttggat gaggtagtcc
    58381 cgcgagaaac tgtcgagtct tgcataatac aaaacttgtt ctacgtattc atcgattttt
    58441 gataattcat tttctagtaa tgtatacttt tgatcgtcaa tatcgaactc gatcgaacga
    58501 actagcaatt tagaagcgga aagtggcact ttgatttcat ggacccatga gtcaatataa
    58561 tctttttggt cttgttgatt actgattgct gattgcatta cttcttggtg ttcacggatc
    58621 agctgattga tatattcttc taccagtttt tcttcttctg tcctcccacc actcaaataa
    58681 ttttgcaaag gggaagtttt ttgtatgtcg gctaattttc cccaccatct tctcttgctc
    58741 aagtaaccac ccagcagata aaaaatcaga aagacgccct caatcaaagc taaataagca
    58801 attgtgctca aatcaacttt gatgtttggc gccagccaca tcacaaagat cgtcaatgca
    58861 ataaaaaaca gccatcccaa gatcaatgtc cactgatctt tcaaatattt aaaaaaattc
    58921 atcttaaccg ctcatccttt cagggaacga tatatccctg tcctactttt gtttcgatat
    58981 atccttggat acctgcctgt tcgatttttc ggcgtaaccg attgatgttg actgtcaatg
    59041 tattgtcatc tacaaatcgt tcgtcatccc acagtgctcg cagcaatttt tcccgactta
    59101 agatctttcc attgtgcttc atcaaaataa ataatagacg atattcattt ttgctcaaat
    59161 caatgatctc tccgttgatt tccatacttc cgttgtcaac attcaacgta atgccattgt
    59221 ggctcatcat ttcactagat aattctgtgt agttgtaaga acggcgaagt aatgcattga
    59281 tttttgcaat cagtacatcg atttggaaat gttttgtcac aaaatcatct gcccccatgt
    59341 tcatagccat gatcatatcc atattcgtat tcctgctgga gataaaaatg atcggtactt
    59401 tcgatacttc acgtattttt tgacaccaat aatagccatc caaaacggga agattaatat
    59461 ctagtaatac aagctgtggt tcttctcttt caaagtctga gaacacttga ttgaaatcgg
    59521 tcgttccaaa ggtttcaaat tgccatttct caagttcctc catgatcaat tgtcgaatga
    59581 tctcttcgtc ttcgactacc atgatttttg ccataaaaaa tccctccatc tttcttcttg
    59641 ctactacaat atcaaagaag cccttgtgaa acaagttggc ttacctggaa aatgtcattt
    59701 tagcaaacgt taaaaaaaac tggaaatatg cgatttaatc gcgtttgtct cttccaagca
    59761 gcttaaattt attatgttat tcttaataat tggtctatta tctgttattt ttctttcgtt
    59821 gtttttgtct tttaaatttt cgataacacc aataaccgaa aagcgttagc actagcaata
    59881 tacctagaag gagtataagt aatcgataaa gatggtattt ttttgtctgt tctatctttg
    59941 aagagacttc ttctgtaaag ggaactcgtc ttcctgtcac tagtaatcgg tgagtgttca
    60001 cggtgtaagg tgtacaagtg ataagtgtga ctagatcctg cttttctcta attgctaatg
    60061 tatttgtttt tgttggaagg acaacaattt tctcaacgac ttcataagcg agcatccgac
    60121 catacacttc aagatagaat cggtcatctt gctccatttc ttcaagatcc gtaaagagtt
    60181 ttttctcagc aataccgcta tgggcggtaa tcacggaatg tgtactctct cctccagttg
    60241 gaaaagaggt gccttgcagg actgtcgctc ctctatctaa caaaagatca ttcgtttcat
    60301 caaataaagg caagctaaca ttgattttcg gaatatagat ggctccgatc atatgttgtt
    60361 cgtaatattc ttttcctgga ttttggacat ttctaaccgc ttgctcaaaa ggatctttga
    60421 cttgtcccat tcctgggatt actgatgtat gagcaagcgt ctgatttttc ttttcatgca
    60481 ctgctaattg ttgctcatgt ttttcttctt tatcgcgttc aagctgcttt tgataattct
    60541 cgatccttct ttgatccaaa taattgctga gagcatctgc taaaaatgga tatgtaaaaa
    60601 ctgcagctcc ggcaagaaac atcactgcca taaataattg taataaaaga ctgatttggg
    60661 tttgaggtct attacctatt ttctttttca ttttcttcac cttcttattt aaaaaaactg
    60721 cagcaacctt tataaaaccg attgctgcag cttatttttg ttgcttatac ttcagacttc
    60781 attttagatt tacggtacca gctgtacgct ccaatcatca aacttattcc gattagtaag
    60841 aatgccaaga gcccgttccc accagtagca ggaagtgacc cgcgtttcat attcggtact
    60901 ctttctggcc ctggattttc tactcctacg atctgaattt cttcattata gcttccataa
    60961 gagatgataa attcagtaaa ggctgcctca cctgttggaa gtacataacc ttctggcgcc
    61021 atggtctctt tcatttgata ggttccataa tctaaccctt gaacctcaaa gtatccattt
    61081 ccatctgcga caaattctgt tgcttgtccg cttgttgccc actcaattct atctgctcct
    61141 gattcataaa cagctaaagg cgactcccct ttataaaata ttgcgtattc agaacggtct
    61201 tcattccaca attcgaatct tgcatcttta agcaattcac tgcttgatgc atcatatttt
    61261 tcaaactttc ttccacctgt tgtgactttc tctggcggct ctactccttc ttcataatca
    61321 aattcatcat ttcgtccgat ttcaataacc gctgtgttgt tatggaaatc atccgcttct
    61381 agttctgtgg aaaccttcaa attatacgtg atcgttaaat ctcctccacg tgcatctgct
    61441 aatctaccta aagtatctac tttggctact ccattttctt ctgtcaaaat cgtcacgaca
    61501 aacccgttgc ttactacttc tactatataa tcttgtcctt ttgttaaaat cgtctcgccg
    61561 gctcgcactt ctatttcctg atcataataa gttagaccaa ctgtaggcgt atctgtgatt
    61621 ttgtaatttt tgataacagc gcttccgttt tcaaggacag aatcgatgaa ataaggaata
    61681 ggtgctgtga tcgtgtaaga agccgttttt cctctttcta gatcaatata agaaatcgtt
    61741 tcttgttctc cagcttcatt aataatcgtt acttgtctaa ggtcgctttc ctctacattc
    61801 atctgtttat ctgcttctct gatttcgttt ttcggataca aatgcacatc tgtattgtat
    61861 gtgtctttcc atgtagaacc atcccacacg ccatccacca tatcaggcat catcactggc
    61921 atcataacaa ccattggaga cgcgattctg gaaatatgag ctggcgaata agtttctaag
    61981 aaaagataga ctttatctct agaagaaggt gcttcttccg tcacttggac ggtagagaat
    62041 accgcttctc cagcttcatt cgttgtttgt ttgtcaatac ttgtcagtcg atattttaaa
    62101 aaccaacttt ctgtgtgccg tttttgaatc cattcaatcg cttcggcaga attaagaccg
    62161 tcttctcgtt ccggtgttaa aggattatct cgaatcaaat cgtaatatac ttccgttacg
    62221 tcaaacaaat caaaatcgac tcctggaata ttttcttcac caaaatccgt agaaaccaat
    62281 ccgctattcg gtcgttcttc cggaacagat gagaaacctt ttttgtgtaa tgtaatcgtc
    62341 acttcacttg gtttttgtgc gacttcttcg gctttgacta gttttccgtt cccgaaaatc
    62401 cctattcccg cagtaacgag taacagtaca ctcattcccg tgacaatcat ttttttattc
    62461 atttttttct ccccgttctt tttttattaa taaaacagca cctaacaata aaagaattcc
    62521 tagtaaagaa atcaacgttc ttgcttcatt cgtttgcggg aatacggacc attttcctga
    62581 ttgacctgga ttgcttggac cactcggctc tttcggtttg tccgttgttt cttttacggt
    62641 ctcgttataa acacgtggtg ttgcggattc ataggcagag actggaactt tcccggattc
    62701 taattcagcc atctcctgtc cgttaactac tacatattgt ggttggcctt ttgcatccac
    62761 ccaaaattca gggatgatga cctcgattct cttacttgct tcatccatct cgtaaccttc
    62821 cacacctttt aattcttcaa aataataggt gccagaaggc aagaaacgtt gtcctgtcgt
    62881 aacaaggccc tctttatccg aaatgaattt gcttacattt ttgtcattca aaggatcatt
    62941 gtctgctggt ttgatccatt gatttttcaa gtcattagca ggagccatat ctaaataata
    63001 tttcccccct tctatcatct gatatagagc aaaaacagca ccttctaatg gttttccttt
    63061 ttcagttgtt cctctttgac gtccatactt gaagaagtat ggatctctta gataaccgac
    63121 atttttagga tagatatgaa tctcttgcag ttcctcggtt gattctgtcg ggtgataaat
    63181 tggcaaaata gcagcaattg ggatagctgt ctgatcgata tcaacatcca atccaacttc
    63241 tggatcaatc gattcttcga aaatcaaata aactgcatcc cgatcttggt ttttcttagg
    63301 tgctttgata cgtgcaatcc cgtctcctaa tccgccaacc gtatctttcc cagttgttac
    63361 cgaagtccct atttggacaa gcctttcttc tgtgattagc tgacggatat tgtttctgtt
    63421 cgtttcagcg atttgctgga cgaattcttt aggagtcatg ttttcagcag cttttttttc
    63481 atgataataa tcggtcatgt cgtaaatggc aaatgtcgct ccatttagtg gcaccgtctg
    63541 tgaaatgata tctgctgttt cccctgcttc ctcagagata gccaagccat cattttcatg
    63601 gtattcaaat tgatcgttat aatcgatatc tcgaatcatc cgtttatgca acacgaattc
    63661 cacgacatct tcccctgatt cttctgccga catcgcatgt ggaagaagga ctgctgcaag
    63721 cggtagtaaa acaagtaatt gaagcatcaa acacaacagc tttttcatta ccttgctccc
    63781 tcctttttag attgtctgac aaacaaacca taggctgctc ctgcaagcgc catgaagaat
    63841 gcagcaagca ggatatagaa taatcgtccg gatcctcctg tagcaggcaa cggattttca
    63901 ggatcgttcc cgacactaag ctgtaatctg attcgatttg tctccaaaag ttcatattct
    63961 aactcttgct gtagatcagg cgtctctgct tcttcgtttg gataatacga aatctcaact
    64021 tttagtgtac ccgcttcttt tcctggaact acccgatcat tttctatgtc aggttcttct
    64081 cgataactaa tttctaaaat aaagtaacct ggaagttttc tatagctgtc aggtgacttc
    64141 acttccttga tccgatagac cccttccaac aagtctgaag cattgaatag ggaagaatcg
    64201 tttggatctg gtgccaagcc tccctcgatg atttcatact ctcctgcact attttgtttc
    64261 tcaattgaaa attctgcgcc ttcaagacgt cggctattca tactgtcaat tttcaaaagt
    64321 tccaaatcga ttggcgctag ttcatcttct aaggttactt gtagtacacc atcgatgatt
    64381 tcatagcctt ccggcaaggg agcagtttcg tcttcgatga ccgtatcttc aatgataaac
    64441 ttaccttctt cattcagtgc aaactggaac acttgatcag atagccgata cccatttggt
    64501 gcgacagatt ccgagacctc atattcacca atagacagat gcagaggttg gtcgtaattt
    64561 aaatcgacat acttttctac tcctacggca cgagaataga agtatccgat cccaggcaaa
    64621 cgtttcgatt cttctggttc taacggatta ccagtgtatg ctcgatacag cgggaaggaa
    64681 gaatccccca ctttcctgat atcgaaacct gcaccatcta atgtatggcc ttcatggtct
    64741 aattttctaa ctcggatctc ccgataatca aacgtattgt aagcagtgaa tgctacccat
    64801 aaacgatcct cttcatctgt tgtatacgtg agatattgcc aattttcttc acctgtttgc
    64861 ttgagttgga tagtccctat agcattatcg taaagtcgca agatccatgt gtcattttca
    64921 tcaggttctt tgaaaccttc tgggttctgg ctctcaatga ttttgtattc tgcatagttg
    64981 gtagtttctt cactatcctt ataaacaaat gaatctggct ctccgattgg atgaataact
    65041 ttctcaccat ccacgattac atatttcccg tcttcatcta ctgaatagaa cgtgagtctc
    65101 cctttctctt cctctacttc gttcacacca gaaagccctt tcgctactgg atatccgatt
    65161 tccagtccgt taccatctgt ttcataaagt tcaaactctg cgccattgat tggcatatta
    65221 ctgccttcaa ttagtttatt gatattcatg tggattggct tgaattcatt tcgcatttcc
    65281 agtttgacat acaactcatc atactctgtg ccttctatgt taggctcttg tacaacagaa
    65341 agcttgtgat attctccttc ataataggaa ttcggatctt taccttccgg tccgccgact
    65401 ctcgaaccag atgtatattc atctacaagc tcgtagtgac ctaacatctc atcttcgttg
    65461 gctgcatatt ttttgatttg gaattgatac gtctcatcta ctaactgata acgtggtggt
    65521 ccagcgatct ctctgatcca aaatatgtcg ctgactgctc cagtttcatc tcctaaaatc
    65581 ggcatcttcg tttcaaagat cgctattccg tccgtggtag ttttacttgt ttcgattggt
    65641 tcggcttccc cactctctgg attttggtca tataatgcaa attcgactcc agccaacggc
    65701 tcgccatttt gacccttctt gctgacttgg aaattacggc ctttatgttc gtaacgaatg
    65761 gaagaagatg ggaaatacat ccgtccagta gtgatatcat tctcataatc ctccaggttc
    65821 tgaatatagg ccatattgtt cactgtgcaa aaatttccgt cttgagctcc cgcatcaagt
    65881 tttacttggt acttgatcct gaccatttcc ccttcaccta aagaaatcgg agaaaattta
    65941 taagcttggt tttcccgtcc gacatacgtt gtcggagtcg ccactacttc tggtggggct
    66001 tgtccatgac gttcttcatc ccatatttct ggctcttggt acttcatgcc gttttctcct
    66061 ggatctagat ggtaaaactg aatatctgcc gatctgccag ctccaaatgg tgagacatta
    66121 aaaccagttt catcataaag tgtggcttgc tggatcgttc tcttgaaggt agaagagata
    66181 tcctccaagg ctgtaacaat gtcattcttg ttgttcgcat tgtaatatcg cggtgttacg
    66241 ccatcttctt ctaaatcagc aatatttttc aatacatttc gtccaatagc atctagtcgt
    66301 tgtctcccgc taacgtttcc atcgattcct aaaccaatgg agaagatact tggcgggttc
    66361 tcttgatact tgtttttcag ccaatgatga taagcaactg tgttgatcgc agatgacttt
    66421 tcttgcgaag taggactgcc attcgtattg ttattagaag aaccatcacc aacccagtga
    66481 gtcgctttat tatctccttc ttttacctct ccataacgat agtgtacatt tacttcatct
    66541 tctggacggt taaagtcaga tgcataggta actggatgag taaaccctgc attagaagta
    66601 ttcccagaaa actcctcaaa atttctgaac aaaacgtcat tatcttcagc aatcttatct
    66661 tccatcacag tccagttgct ccaagctcca ttagtgctcg tacgataact tgactgaatc
    66721 ggtgcataac tgaaggtcgg tgtcccatct cccacaacga ttaggatttt ttctggattt
    66781 ctattttctc cgccattgtc tttatacaat gtttcatagc catttttaag ccctagtgta
    66841 agcggagttc ctccgattgg tgtacgattt aatgctgtat tctcacttcc cgtcaaacga
    66901 ttgatatcat ttgtcaatgg aaagatgtcc gaactgattt gctcatggtt attgatagct
    66961 gtactattat ggtaaaaatt caccataccg attcgaatat ccagactcgg gtcagagagc
    67021 agatctttac tcatttcgtt tactgcctca atcaacgcag catttttagt ttgactattg
    67081 gtcccagcgg ttaattcact catactcgct gacttatcta gaacaaaaac gatatcgatt
    67141 ggactgattt cctttttctc gcccccgatg acatctagat agacattgta aagggttgtt
    67201 gcatcttcag gatgtagatc agatgctgtg ctgcttggca gaacaggttc tacccatttt
    67261 ttgatgtacg ccccgttata atccaagtaa ctgttttcaa aattccgttc atttccccaa
    67321 agctgaacgg tttgagctgg aacgtttcta tcttcttcgc ctgcagttga tccattatta
    67381 gtagcatagt cgtaatttcg ccagttcgct cccccgtttg tataatcact atcatcgatc
    67441 aagttctctc cgtcatatgg cgagcctttg tctccttgat agcgttcatt gctttgtgtc
    67501 caatttccta acacttttgt atagtcattc gttgtaaact tcatctattc tttcatcaac
    67561 caccacttga agaggtagtt acccttcgtt cacatcgggg atcttttctg tttcaaaaat
    67621 caatgtgccg gtttctgctt cttttgaata aacttttccg acataccatt cttgaccatc
    67681 gatcgtctcg acttttaggt cttctccatc ttcatcatag gaggatagac ctgttccacg
    67741 aacgtttttt acggtaccaa tcccggcggc tgccgcatcg attgctaaac gtattctacc
    67801 ttcattggca ctttcctttt tttcaaaagc cagatgccat tcaagggttt cttctttttc
    67861 aatatacttc ccttcaattt ttgcatagtc ctcatctaag aatacctcat cctcctttgt
    67921 ttctgttgac tcagcagcta catccagggt cgtcatatga tagactgact ggaaatatgg
    67981 tccaaatagc aaactgacag ttactaactg caaaagcttc aattttaacc ctttcacatc
    68041 cttatactcc tttcaaaaat atttgtcttc tttcacaaca atcaacaaaa caatgcccat
    68101 ctaattataa tttaatttaa ttttaatttt aaatcaaatg atatcctttt tagttaaaaa
    68161 acaccaatta tacaacattt attattaaaa ttaaattata aaattttata acgttctcat
    68221 ttaacaaaac ttaagttatt aagacaaatg aataaacaac tacgctttcc tcgaaacaaa
    68281 aaaataaagc acaaatgcgc atttacgcac tcatgcttta ttcgtacaat taattcagat
    68341 aacggcagcg cataggatgc caataacact tcctaaaata gctcctccta aaatgtcagt
    68401 aggataatgt aaaagtaaaa aaatcctcga ataagcgatc aaacaagcaa ataaaaaggc
    68461 taatattcct gcaactggac ttaattcgaa caacgcagct actgataaaa aggctagcgc
    68521 tgtatgtcct gaaggaaaag aagaagtctt cggtttactt gtgtaaagga caagccgacg
    68581 atttttttca taaggtcttt tccgtcttgt cgtttttttg ataaaaagca aaccaacaaa
    68641 aaaatagatc aaactgccga taagaatggc tagaccatat tctctagtat caggtatcaa
    68701 gactaaaaca gcagcaagga gcaaccaaat aaaaccacca ttagagatat tactgataaa
    68761 tttcaaaaaa ttgatttttc gactatccgt tttccgttgc ttggcgaact tgttgataat
    68821 actatcatcg attttagcaa tcaaacgcaa catgttattc ctccttttta agaacctttt
    68881 cttgcgtacg atggataaaa agcaggactt gaaaataaaa caagaaactg aaacctaata
    68941 aagcaaaata gattggtcct gcaaaccaga atgcgacaag aaggatcaac gtgcctgcca
    69001 aatagaaaag cgcgcttttg aaatcattaa aaaacaagaa aaatgcagta atccaagaag
    69061 cttctttttg ttccagttga agcaagattt tgtaactaaa gagaagcgcg cttaatagaa
    69121 gcaaaaacaa cgtagtatac atcaatgtat agccaattcc cccaccccaa tagcggaaaa
    69181 tctgataatc gatcaataga agaagaaaat aaacacttgc taaactatct tgctttccat
    69241 aaaaagagaa gttctcacga aactttttcc agaatagtga accgagcttt ttctcttcat
    69301 tttttttgta atgataaatc atatacagaa ctgttcgact tgcagttcct aatgtgaaaa
    69361 caggcaagac gcacaggaac catagtagct gtaaatggat aagacgtgga atccattcaa
    69421 tgatttctaa gaaataatca ttggcttttt taccaatcga tcgattcatc atccttttga
    69481 acctcctgtc aaatccatcc cttcaatgaa ataacgttgt gcaaaaaaga acagcaaaat
    69541 cgtcgggatc aagacaagtg ttgctcctgc catcagataa ttccattgtg tcgttgcttg
    69601 gttctgaaaa acttgcaagc caatctgtaa cgtgtatttt tcttgatctt ggatatataa
    69661 cagaggacct aagaaatcat tccaagctgc gttgaaggaa ttgatcgcaa tggtaatcaa
    69721 ggcaggtttc gtcaatggaa gcatcaaatg actccaaata tacaaatgat tcgctccgtc
    69781 gatttcagca gcttcgatca attcattatt gatcgataag taaaattgac gcatcagaaa
    69841 tatattgaac gcattgccga agaacgatgg aacgatcagg ggcaaataag tacctaccca
    69901 gccgatcttg gagaataata catattgagg gatcatcgtt acaaaccccg ggatcatcat
    69961 cgtagaaaga accaaagcaa acatcagctt tttcccagga aaatcaagct tcgcaaatcc
    70021 ataagcaata aaagaatttg aaaggacatt accgatcact actagcacag tgatgaataa
    70081 tgtatttctt gcatagcgcc aaaaaggaaa ggcggcaatc gtatccagat agttttccca
    70141 tacgattttt tctgggaaaa aggtcggagg ataacgaacg atttcttcca ttggtttcaa
    70201 tgaagtaaac accatccaaa gcaatggaat gatcaaaatg attcctatta ctgtcatgag
    70261 gacataactt agtatttttt ttgtttgccg attcacactg gtctttttga aataatccat
    70321 catttgccgt cacctccaga ataatagacc cacttaggtg caagcttcaa attgacaaac
    70381 gtcagaacca acacgatcag aaacaggatc attgacatag ccatcgcata acccatatca
    70441 aaagctacga acgccttgtt ccacatatgc agattataaa aaagcaaaga atttgcaggt
    70501 ccgcctgttc catttttcgt catgacataa gcttcttgaa aaatttggaa agaaccgatc
    70561 gtagaggtga tcacatcgta aaaaataata ggagtgatta atggcaaagt aatacttttg
    70621 aactttcccc aaacgcctgc tccatcgatt tctgctgatt catataaaga tctaggaaca
    70681 ttttgtaatg tagctaagta aagtagcatt gctcctccag aactccatat tttcatcaaa
    70741 atcaacgcag gtttcgtcca ttgtggatca aacagccaag ctggtccagg gatatggaac
    70801 cagcccagaa atgtgttgat caatcctgca gatggagaaa gcagctgcat ccataagatg
    70861 tagactgcta ctcctgataa gactgccggt aaatagaaag ctgtacggaa tacactgatt
    70921 cctttgattt tttgattgag tactgtggct aaaaacacac tgaaaatcgt cgtcagcggt
    70981 acattgaaga tgacgaaata aacggtgttg tataacgatt tccaaaataa atcatcgtga
    71041 acgaacattc ttttgaaatt tgctagacca atgaaattca tcttggatgt caaattataa
    71101 tcggtgaaac taccaataac tgaaaaaagc ataggcccta gcataaatac caagaacccg
    71161 ataataaaag gcgagataaa taaataggcc catcttgctt cttttttctt tcggatagat
    71221 aaacgcttca aattttcttg cctcctctgt acctagacag tcaaaaatgg attattgatt
    71281 ttgcttgact aagttttcta ctgctttttg tgcatctgcc aatccttctt ttggtgattt
    71341 tgttcctaaa agaatctggt caatctgttc attcactaat gtcgtgtaat ccggagcatc
    71401 taaaggaact ggtgtgatca ccgtattttt aaagttttcg tccgccattt gatagatcat
    71461 ttttccttta tccgttaggt tgtcattatt cactaaattc tcattggctg tcttgctcgc
    71521 catgatatca aaactttttt cgccgaattt ttcttgtact tctggagaag aaagatattt
    71581 gatgaattca taagaggcct caggatcttt tgctccgtat ggtacttcca agacgaatcc
    71641 gccaccccac gaccaatggc ctgaaccttc ttctttttct gggagctgca tcacgccaaa
    71701 atcaaaatca tccggtgcat tttccatcaa actagagtaa taattgatat tttgggcacg
    71761 catggctact aatccggaaa taaatggatc agatacacca gacccaaatt cggcttctaa
    71821 tttattgatc gtatttttcc cataataatc ttgccagtct tggatccact ccaaggcttc
    71881 cactttattt ttagtatcaa tcttgacttt ttcatctttg tcaaaccaac tagtcccgtt
    71941 atctgcgttt agcgcccata catcagcccc taaattccat aatggataaa aaccgatgcg
    72001 tgtaaattct tttccttctt ttttatctag tttacgtgct gtttcttcta attcatccca
    72061 agttgtcggt agatcttgtt cactgattcc agcttcttta aataactttt tattataaaa
    72121 aatgacttgt gtatctgtat tgaatgggat cgcataagga tcaccttcat attctactgt
    72181 atcccaaagc tgcggataaa aatccttaga agtgtctttt tctacatatt tggagagatt
    72241 agttgcttgc tgtgcttctg ctctttgggc aacggaattt atgtcctgta caataacatc
    72301 gggtgcattt ccagctgtta ttgcagataa agatttagtc cagatgtcac cccatggctg
    72361 atacttataa tttacatgga tctcgttttg tgattgattg aaatcctcaa tgatttcttc
    72421 gatagcttct tttcgtgcac cggatcccca aaaggaccag aaatcaatat tttttcttcc
    72481 atcacttgtt ttttcagaag aatttgctgc acttgaactg gcatcgcttg cattacttga
    72541 tccgcatcct cctaataaaa acaatgctga acttgccagc aaccctgtaa acaataattt
    72601 tttcatattt tacctccaaa ttttaatgta accgatgccg gttttaatat aacgatatca
    72661 ttttgttctg aaaataacaa tttataaggt atgattctaa aaaaattatt aatgatacca
    72721 atactttata taattcgcga gcgctttctt tgaatttttt aatctttcgt agcagaatga
    72781 gaatgtatta aaaatagatt aggaggaatt ttgatgttta gacaccagaa agaattgcag
    72841 tttgaagcaa aaccagatcg tccgaatcca ttaatcgcga aatatctgca ggagctgatc
    72901 ggcggccaat atggcgagat gagtgtagct atgcagtacc tgttccaagg ctggagctgc
    72961 cgaggagaag aaaaatataa agatatgctg atggacattg caacagaaga aatcggccac
    73021 gtggaaatgt tggcgacaat ggttgctcgt ttattagagg gtgcgcctgt tgaagatcaa
    73081 gaagcagcga tgcaaaaaga tccaacaatc ggtgccatta tctctggaat gaatccacag
    73141 cacgcgatcg tagctggctt aggacctcgt cctgctgaca gcgtgggcaa tccatggagc
    73201 ggtgcctata tcattgcgag tggcaacttg ttagcagact ttagagctaa tttaaatgcc
    73261 gaatcacaag gaagacttca agtagcacgt atttacgaaa tgatcgatga tcgtggcgta
    73321 aaagatatgc tgtctgttct ccttgcaaga gatagctatc atcaaaatct atgggaatgt
    73381 gcagtgaaag aattagaaga aaaagaaggt tcaatcttag tcccaagtac tttcccgcgt
    73441 gacaaagaac gaaaagacat tgcttatgac ttctataact tctcagaggg agaccaaagt
    73501 agtgaaggtt cttgggctag tggcaaagca ctggatggcg aaggcgaata tcaatggttg
    73561 aaagaaccta agatcgaagg cgctgcacca aaattagaac cagtaacacc aaaaatgtat
    73621 gggacacctc cattcaagaa ataaatatct acccgtagaa acacccgttt tttgttccac
    73681 acgctttgtg agcaaaactg actaaagtca ttaatcataa ccacccttca aaagggtggt
    73741 tttctctaga gctataagct caaatcaccg gccagcgcct aaagacgctg gctttcatat
    73801 tttatgttca agccatattg cctttgccag ttttgcccac ctcttaaaag gtttatgtac
    73861 tactccttag cccttaaaag gatcgtctta ctctcgtaca ctcagcttat ctaacgcact
    73921 atcatgtttt tcttgttctt gaatgtactt tttgatggtc gcttcatttt gtcctacttt
    73981 tgtcacatag tatccttcca cccaaaagtg tcgataccca aatttatatt ttagatttgc
    74041 acaatctctt gatgatctcc tgaatattgg ctcgatattg attataaatt atttttcttc
    74101 tatactttgg tgtgaataca atgtggtatt tacacatcta ctttgtacgg gctaaactat
    74161 ttccctttat tgctccaccc gcatagcaag tggttttgta tttcaatcgc tcggcgcgct
    74221 caattaggtc taaagacaat aaatctaaaa acccgctgct tcactgacag aaacaacggg
    74281 ttttcagaaa aaaatgaaat gaaaaagatc tcttacggca atctatttta tttttttgat
    74341 tttttataaa tggaaaatgc ttcaagaagt ccaagaaata aagccgtata aaaacaagaa
    74401 cctatgaaat ctttatttat tagatattca acagaaatcc cgataacact agccaacaat
    74461 atatttatca gaagtgtaaa ataaggatgc tttttataga atagaactag tgttgttttc
    74521 atagactctc ctttcttcat atttccaatt aatcacaaat tcacggcatt actagaaaaa
    74581 ttaaaggggc gcagaagtgg aaaaatactc ttcgactttc cctacaaacc aggccatctt
    74641 gtgtttaata actataccaa atctaaggta cctctaaatc taaattccat ttgtggcggt
    74701 gacctccaat ttttaactct tctatctccc atccagtata cataaccttg atacttcgac
    74761 cacttatata tcgaacacac aaatacctat ccattgcagg agtactacct aacttagttg
    74821 ctacttgcat ctaaataaca gctgaaaaga taggacttac tcttagtaaa gtatctgaac
    74881 tattaatttt taaactatca tttttatcct caactacatg cacatctgtt gcaacttcac
    74941 tttctgtctc atccagataa atgattaagg aatcgggaat tgcaatatct tcagctgacg
    75001 ctggaatagt tgagctaaat tagtcatcat atctttatta taaaataacc aacagcaaaa
    75061 aatacaatga aaaacaaact tggaactaat gtatcattaa taaatgttga aaaattcagc
    75121 aactcattac tgtatgattt tagcagccca accaacatat accctataaa agctaataag
    75181 atggttagga atcctttaga atttttactc attcatagac acttccttaa ataactttta
    75241 ttatagaagg tattgtaaat aataatattg acaaaaagtg actcaaaata aaaaaaaact
    75301 tacattatac tggaatgaac tgtattgata gtgtacctaa aagctctact gacataagat
    75361 cgtgtaatcg gtaaagtaat tttattaatt atacgggatg taatcaatta gagaataaac
    75421 taatcataaa aggtactttt acattcataa ttgtcgcttt gagattctac tttggttcac
    75481 tatctgaccc aattgcacat tttcgatcat tacaagtatt ggtgtcgtta gaacaactaa
    75541 ataaaaacta gcggtagatt tttcagaatc tatgctaatt tctgtatgga tgttccagtg
    75601 atggcaaatt tctcttttca ttgtttttct tgtcgcatga tatgcctttt tgtgttattc
    75661 agttaaacta tagaaattct ttcctagaca gatcttgatc ccaaatttta cgtttttgag
    75721 catcgatata gtttaaaatg acattactca tatctaaaga gtttagattt tttaggacta
    75781 aaactgtcag ttgttctttt tcttctttct gttaaagtat tgtcgcgact tttcgtatac
    75841 gttaagatat gtcgtgaaaa aacaagtttt gtgacacaaa aaaacgaatg acttgaggaa
    75901 atcacctcaa tcattcgttt aaaatgctat atattcttta gtttaagata cggaaattaa
    75961 tgccatcgac cacactagta gaatgaacga catttacttg gccttttttt aatttcgtta
    76021 tgtttagcat ataaaaatat tatagagttt acttacaatg cttaaaacat atactgtata
    76081 atctgatcaa ttttagccat gtcttgcaat ggtaagtttt ctattttttt gagttttcgt
    76141 tccttaaaat caagagattt taattgtgta ataattactt gtccttttat atctagctct
    76201 tcaggtaatg agtaacgtgt cggtaaattc tttatagtgg aagtaattgg acatatgacc
    76261 gaaaacattg ttttacggtt aaattcataa cgagagacga ctagtcctgg tcgtcttttt
    76321 tgaatttctt ttcctacgga gggatcaaaa tcaatccata caatatcacc ttttttagga
    76381 atataaattc tttcttctga cactataaaa tttctctccc ttcaggagtt aaatcttccc
    76441 attcgtcttt ctcataatac tcggcctctt ccccaccact aaatggatct tcaatttttg
    76501 gaactaacgt aattgttcca tcatcagaat acacaacgat atattcttgg ttttctgaag
    76561 gtttctttcc gttatcagaa ggtaaagtta ccactacaga acttccttgt aatctagatt
    76621 ttgtaacaag cattatcatc actcccttaa taaaagtata ctatataaca ctaagtaacg
    76681 caaaattccc ctttgtaaac tatctagaaa attgttttgt ttaaagtata tcttattgga
    76741 tataaataga aataaattgt agccagttca ttttttcttt aactaaaaaa ataatccaag
    76801 aaacattgaa cctatggatc caaaagctac ccaaatacta tagctaaccc cccgctacct
    76861 tcaattttgc agataaaacg ctttgggaga aaatttcaaa gacaacaggc catcctatca
    76921 tgcccgatta taaacaaaaa gctggctatt ccttttgctc tgacaaattt caattgggaa
    76981 agttcacgaa actagcaggt gaagaagttt caactgttcg gatcaaagaa tgcccgcttc
    77041 aaatagaaac attggttcaa cgaatttcaa ctagacaaga ctttgctatt gtagaacgtg
    77101 agatcgtagc tatttttgta gaagaaggga ttttacatga tccaactcat atcaatgtgg
    77161 ataaatggca acctcttatc tataaattca gagaatatac aactgccaac cagtcgttaa
    77221 ctttgaattt tagattccaa gaattcaaag agtcataatg ataaacatcg ttaggtataa
    77281 ataaaaaaga ctcgcagcac gagtaaaaaa caaatagaag ctatacatta gaaaggtcga
    77341 ctgtgaccct atagatgcag tatatgcagc ttatgagcat ttcttctgtt ctctttgttt
    77401 ttgggatctg tgctgaagtc tttttcgttt tttgccgctc tttctttgaa aaatcgatta
    77461 tgttatacct tctccattac taattcaggc atctgctgag taatgatttt tcgcgcaaaa
    77521 gaaatatctg ttacccaagg ttcgatttgt tcttcagtca agacaagcgg cattcggtca
    77581 tggattggtg cgactgtgcg gttaggttca gtagtcatta tgattgattc tgccattttt
    77641 tcatcctgat ggctacgata aaaaccgcca atatacacta ttttttcctt atttgaaaac
    77701 ataaatttgt ctttttcttc attccactca ttgggaaaac acaacgattt tgcaaaaatg
    77761 gttgatgaaa ggtctttttt tcttctactg tctctgcacg ggcattaatc atcaattgtc
    77821 cttttttaaa tccggtaaat ccccacttca tgatttccgg agtgaggatg ttttcttcct
    77881 cttttcttaa cgtcacaaca agatttgacg gaaaaacttc tccagctgct aattctgctg
    77941 cctgcttcgg ttgtttcgtc tgggcttctc gataataatt ctgaaggagc tctgactcta
    78001 gatcaaaaaa ataacgacca cacatcctaa tccctcccaa tctttttttc tatcatacac
    78061 tgcaacaaga agttcgcacc aacaaaacac tttcaatttt tgtagaacta aaaaagttgt
    78121 gacaagtgac aaactctcca gtgaatggta ttctcctgcc aactcctcgg tcacaagtca
    78181 caatattcaa caaacatgag aagctgcttt ttgaaattgt tccttgtgac tcggagtgaa
    78241 acggcaggct tacgacctct gggtaaacgg tgttcaaaag ccagtttctc ggtattaagc
    78301 caaatttatg caaaaatgta gaaagctatt ttcacaaaat ttttcttaat actcgaaact
    78361 aagcgacttt ttcacaacct cttccttaaa cggtgttcaa aagcttgcat ctgcggtaat
    78421 aagcccaacc aaacgaaaaa tatgagcagc tatttttatt tggctgttct tattacttga
    78481 tgcagggcag ctttttcaca acctctccac taaacgatgt tcaatcagct aaccttcggt
    78541 attagctcaa aaaacggcaa aatatgagga actattttgc cgtttgtttc tctaatactc
    78601 aggtcaaagc gctgatttca caacctctaa tacacggtgt tccagaagta gcttcttcga
    78661 aaaataagcc gaaatttcac aaaaatttga gaagcaattt tcgtaaattc cttcttattt
    78721 cttgaagctg accacttctg tcacaacctc taattattaa agaacctttt gcgaagttaa
    78781 caatctttct ttgaccaatt gaaaattctg cctaagtagt gatagatcct gtgtgacttt
    78841 caacaataag atacttccct ggatttcagc aatcaacgct ttggcttgac ggtctgcttc
    78901 ttcatcggac agtttttctt cagaaagtgc caggatattt tgtttcgtat acttgaccca
    78961 ttgattgact aattctagta gcaacagacg gtattcttca tccactgtac tcaactcaat
    79021 aatcaaatta cctacaggac agccatgata agtgatctgt gtctcatgat cagcgaaaat
    79081 ccagtccaac atttcttcta atgcttcttc tggctgtttt ccagcattta agatgtcttc
    79141 gaacaattct gtctgccata cgtccatatg cgcatggatc accgctagac aaacttcttt
    79201 ttttgaagaa aagtaataat aaaattgacc ttttcctgta tcagaagctg ctagaatatc
    79261 tcggattgac gtttcatgat agcctttttt ataaataaga tctttggtcg cttccaagat
    79321 cttttccttt gttttcaatg atattctcct ttttcatttc tcatagtcct atattataca
    79381 gtaaattcat cattttttct tcttaatcgt ttaaaaaaga ctgtgccaaa ttatctgaca
    79441 cagccctcac tataaaactg ttctcatata gctagatgtt cattgattca agaactgcga
    79501 ggacaaaagc aattcctatc ttatgatagt tgctctaata cttcctctgt tgtcatcact
    79561 tgatctgcaa taaagccaaa gttcgtcaac gctgcatcca ttgcttcttg gccaggagca
    79621 ccaattgcat ctgtcgctac cacaacattg aatccactct ctaccaattc acgcatatgg
    79681 gaatcgctac acaagtttcc gttcattcca ccaagaatta ctgtgtcgat tccatttttt
    79741 ctcaattgga gcgccaaatc attgctttct ggtccaaaga ttttatgagg agagctgatg
    79801 atcgtatttt catccaaata aggtttcaat tcttcgataa aatcggctcc tgaaccttct
    79861 tccactgatt catattgact ttttctagca aacatctgct gctcaagcat catatgttct
    79921 cctgcaccgc caaattgcca tttatggtca tgtgggtaaa aataatgagg agaaataaag
    79981 agtttgtatc ctttttcttt tgcttgtttt accatttcaa tcatattttc gatcgtattg
    80041 tatttttcta agatatcttt tgtcaaacca aagccaccgc ctgctggttt caagaactcg
    80101 acttgcgggt cagtgagaac tactgctgta tttttattat tgaacatggt ggattctcca
    80161 ttcgttattt attttaatac atcatttaga gcttcactca ttgtcggatg agaatagatt
    80221 tgatctctca ataacgtata aggaagtttt ccattcatag ctagcgaaat caagttgatg
    80281 acttcatgag aatcttccgc atagatactt gcccctagaa tcaagtcagt ttcagggtcg
    80341 actaaaactt tgaatacacc tttaggatct tctaatactt gtgctttagg gacaccgctt
    80401 gtcatatact tgaataattt gtaattgacg ccttgtgctt tggcttgttt ttctgttaaa
    80461 cctacattgg ataaagtcgg agtgataaat acactgtaag gcacagcttt ccggttattc
    80521 gttgttcgtt tattctcgcc cttcaactga tccataatga ttcgataatc atctagagag
    80581 atataagtga actgcaatcc gcctttgacg tctccaatcg cccaaatgtt gtctgcatct
    80641 gtacgaaggt attcatccac agcgattgct ccgcgatctg ttagtttaac atctgtattt
    80701 tctaatccaa gtgatgctgt acttggtttt cttccagttg cagccaaaac ttttgacgct
    80761 tggattgtta cttcttggcc atcttctgta aaggtgacgg cagctgttga ttcttggtct
    80821 gctacttgat ctacagatac acctagatgg aattcgattc ccgcatttgt catgtcttct
    80881 aaaatcattt gcgcgatatc ttcatcttca cgtggaagaa attcagaatg ggcatcaaga
    80941 acgacaactt tagatccgta ttcattgaac attgatgcaa attccaagcc aatatatcca
    81001 gccccgatga tcactaattt ttccggtaat tgttcctgat ccatcgcttg cgtagaatca
    81061 atcaagtagc gacttgtatt caatcctttg attggtaaaa tgattggttc agaaccagta
    81121 ttgatgaaaa tccgttcgcc ttcaacaatc actttttcac cattattcgt cacttcgatt
    81181 tgatggttag aaagaaaacg tgctgtaccg tccatcactg tcccagttgc ctcatcgctg
    81241 atcatatgat aatttttggc gcgaagcatg cccgtcaatt tttctttccg agcaacagcc
    81301 tctgtaaagt cgattcctct ttctccattg aaaatcaatg atttagaagg aatacagccg
    81361 atgttgatac atgttccgcc atacatacgt gttgactttt caacgactaa aaccgattca
    81421 ccttttgaag ctaacgcctt cgctaaagtc ttaccgccct ttccaaaacc gatcacaata
    81481 ttttgatatt tttccatcat ttttccctcg cttctttttt acctaccgat tggtacaaaa
    81541 atatgataac cgataattgt ctattctcca aatcatctgc tttatttgtc aaaaaaaacc
    81601 agacaaaaag cggtcctttc acgtttttag tctggttcga tttcctttat tcttctaaac
    81661 aatcgttact tctacatcga tatttcctct agttgctttg gagtaagggc agaattcatg
    81721 cgcatcttct gcaatttttt gggcttcttc ttcgctgatg ccatcgatat gcacttcgaa
    81781 tactacaccg atctgatagc cgccatcatc taaattataa agagagacac gtgcttttac
    81841 tgtggactct gctgtcattc ctgcttcttt gatcatatgt tgtaccgccc cattgaaaca
    81901 agaagcataa cctgctgcaa ataattgttc tggatttgtt ccttctgcat ggattcctgg
    81961 aggagtgatt ttcatatgca tcgagccatt tggtgcctcg acttctccat tgcgcccgcc
    82021 atggttgatc attgctgttt cgtatgcttt tttcattgta ctgctccttt cgattgacca
    82081 tttgctactt ggctataatt atagtgtatg acaagtaagg cgctttctac aaaaattctg
    82141 cttattcgaa taccagaatg ccgtcttcta ctatttttcc aaaaaacaaa aaaatactac
    82201 tcgtgaacaa cagcgtcata tttgttccaa aataaatagc aatcttttct acataatctt
    82261 ttatatgatt gattttaaga tacatatata ccagaaagtt gaccccataa accaatactg
    82321 ttaaaaaaat aaccatattc gttaccattt tttcctcctt ttgctggtct ccctaccagc
    82381 actcgattta accataccac tttttttgcc gtccaagcaa ctagcctttc aaaaagactg
    82441 gtttattctg ctgttaatga ttcaagatca gaaaaatgtc cgaataattt tgctaatttt
    82501 actaacgcca acttgttctt tccgaattca tcattttcta tctgtaatac tagtaacggc
    82561 tcatgtaagc ttaaacggat caaaaaccag ccgtttccgt atggctcttc tagatcatat
    82621 cgaatacctt cttcattttc cgggtcgaag ttcatccctt tttcttcttc caacagtcgc
    82681 ttcatttctt ctaatatctt gtttccttgt tcgcgtggtt catcgctgaa caattttaat
    82741 cggatttctt gtacttctac gggctgtttc aactctttga tttgttcatc taatgtgata
    82801 ccttttcttt ttaattctgg caaaagcatc aggatctttg cgatgacata tgcaccatca
    82861 tccagaaaat agttttcctt gaatgcagcg tgtccgcttg tttcgatggc tagctgtgta
    82921 tctttcccaa gacggttaag ttctaatgct ttattgatta catttcgata gccggaaata
    82981 taacgaactt ggatgcctcc tttttcttca atgaatcttt gtagatgaga agaagtaggg
    83041 gaattcgtca cgattcttgt tcctggatgc tcttttaata cgattgtact taatactgcg
    83101 atcaaattat ttcgattgat cactgttcca gaagcactga caactgcaga acgatccaca
    83161 tctgtatcga aaatgatccc aagatctgct tcatttgcta aaacagcctg cttgatactt
    83221 tccatcgctt ctttattatc aggatttggg atatgattag gaaatcggcc atctggttcc
    83281 aaaaattggg aacctgttga atccgcacct aagctattca atactttttc agcaaagaat
    83341 ccaccagcac catttccggc atcaacaatg attttccaac catttagtgg tttgctttct
    83401 agtgttccaa tccccttttt aatttttgtg actaaatctt gcgcataagg tgtcaaaagg
    83461 tctgcttttt ctacgcttcc agtttgttcg ctttttattt tttgctgctg tgataggata
    83521 aaagcaatat cttctttttc tgctcctcct tctgaggtaa agaattttat tccattataa
    83581 taatagggaa gatggctagc agtcagcata accgcagcat cgcacgagaa ctgttcaaat
    83641 tgagtggaca taaacatagc aggcgtagta gctaattcga aatcgatgac atgtatccct
    83701 tgttctttca gactttggat caacgcctct ttcagtgctg gtccgcttat cctactgtca
    83761 tgaccaatcc caatcgtcca ttttttattt ggatcggttg atttcttctt tttctttatc
    83821 cagtttgcta gtccccagcc gatctttttt accatgtctg tcgtcaagtt tacttcatat
    83881 ccttcaactg gtaatgcgat tcctcgaata tccgatccat tttgcagcgc tttcatatct
    83941 ttcatataaa agtcctcctc atttattccc tcattttttc cagcttttct gcaaatcgct
    84001 gtgcttcttc ttctgagcgg caaataataa tgaatgtatc tacaccggcc atcgttccga
    84061 caacttcagg gtaagccact tcatctagcc aattcgttac cacatcggca ccatttcgtt
    84121 cagtcaatac gataaccatg aactgaacag actggatacg caaaacctcg cgtctaattg
    84181 ctgtacgcaa acgttcttca tttaaagaaa cagatggctg gttaaataat gtatagcgta
    84241 ctattttgtt ttcattttga ctttttacta acttcatttc tcgaatgtct cgagaaatcg
    84301 ttgcttgagt cacatcggcg cctgcttcat gcagccgcgc aagcagctct tcctgtgtcc
    84361 caataggttg ttctgtaatg atctggcgga tcagtgcttg tcgctgtttc tttttcatat
    84421 tagacacctc tcaatgttga ttatagcaaa agataagtaa tatttcttca tattttggta
    84481 ttttttactt ttattttttg ttttcattca ggttgctaac ctttttctat tttaacacgc
    84541 aaaatcgtct tcattttttc aggtgctgat tttcttggat cgctgatgta aatctctttg
    84601 tgttctttag aagctctttc atagccttct tttgcgatga atgcttctaa tttctcaaac
    84661 gttgctggtt cttcggcata gggcccgacg tgtaagattt gggcacaaag accttcttcc
    84721 atctttttga atactacttg ttctttcaag tcttccggaa gtttgctaga acgctgaatg
    84781 gcttcttgtg ctatcgcttc tgtaacaaag tcaggctgtc ggatcatcaa ttgataagaa
    84841 aaatgttctt ttttcatcac tggttcatgc aaatactttt cttgcagtcc ccattgtcct
    84901 tccagtggat agacagtata catctgataa tcaggaatca gccaattttt tttaggcgac
    84961 atgcgtattg catagctgac tgcatataga caggctactc ttcgtttaaa gtcttcctga
    85021 ttcgggtcgc cgatccctct gatgctaaag aatgattttt taggaacctc tagtatttgc
    85081 gggctttttt tcatactata gctcttgtct ttacgccatt caattttttc catttttctt
    85141 cctccgcgaa attccattta gttatttatt atcatacctc tttttgagtg acttggctaa
    85201 tcgtgttgac actatttttc agtttgtgct agaataagtg aagtaaataa atcgtacaga
    85261 taacacgttt cggcgtgtcg agagagaggc ggtttctatt tttataatag aaatcactct
    85321 ctttttttac gaaatttttt agaggtgatg taaatgacaa aacaaaaaca gctgctttta
    85381 gtacctgcag taattgcaac agggatgatg tcttttgcgg gcgtattgat cgagacggcc
    85441 atgaatgtaa ctttcccaac tcttatcaga cagtttgatt taacgactgc acaagtccaa
    85501 tgggtaacaa cgatttatct tttgatgatt tcgatcattg ttccgctgtc tacttatttg
    85561 aatcgcaatt ttagtctcaa aaaactcttt ttagcttcaa atctgctttt cttggcaggt
    85621 ataatgatcg atttcttctc tcctaccttc atggtcctat tgtttggtcg attgctccaa
    85681 ggtgcagcga caggtatcgc tcttccgttg atgttccata ttatcttgac atttgccccc
    85741 ctcaatcgac gaggcgcgat gatgggtgtc ggtactttga caacggccat tgctccagca
    85801 attggcccca cttatggagg cattatgact tcacatttta catggaatca tatcttcctg
    85861 tttcttgtgc ccgttttgat tctttctttg attatcggct ggtttgctat tcccgagatg
    85921 gcagtacaaa aaagtggtta tttggattgg ataagcgttt taggaatttg tcttttgttt
    85981 agtggaagtc taacattttt gagtacgttg ggaacagttt ccagctggat tgctttaatc
    86041 atcggcggta ttggctggtt ccttttttac tatcgaagta aaaaagtgga gcatccactg
    86101 atccgactgt ctattctttc aaataaaaca ttccgcttgt ttttgattgg cttcttagtt
    86161 tatcagtttt tattacttgg tgtatctttt gtcttgccga atttccttca gatcgttcaa
    86221 ggaagtagtc cttttgtcgc tggattagcg atgcttcccg gcgcagcggt tggtgctttg
    86281 ctttctcctt tttccgggaa aatgctggat caatatggtc cgaagaagcc aatttttgct
    86341 gggctgattc tttctttgat tggttggcta gcattattcc tactcatagg acacgcttca
    86401 gtgggtgtat tgattgcttg tcatgtgttt tatatgatcg gtatcggatt atcttacagc
    86461 aatatgatga ccaccggaat gaatgcactg aatgaagaac tacaaggaga cgggaacgca
    86521 atgttcaata ccttgcagca gttttctggc gctgtggcta cttcattagt agcggtcatt
    86581 atcaattacg tccagcatca tacttcccat aactatgaag tgtctactac attaggatca
    86641 aaagcagcat taggcgtctt gttgctgttg cttctcgtaa gctttgctcg attcgcctat
    86701 tatctgttct ttgctaaaaa agcgtagatt ccatatacgg caggtgttgc atctgccgtt
    86761 tttttgtgtg aaaatggttg tttgtaaaag gaggcttttt tatggaaaaa attgccatta
    86821 tcggtggcgg gatcattggt atgaccctag ccagttactt agatacatca aaattcaatg
    86881 ttgctttatt tgatgaaggg acaggacagg caactaaagc tagcgctggg attatctccc
    86941 cttggttgtc gaaacgcaga aacaaacaat ggtatcgtct ggctaaagac ggcgctgctt
    87001 ttttccctaa acttataaaa gatttccaac ttgatcaaac gatttacgca caatcaggga
    87061 cacttttgct tcgacctgaa aaagatttag ctgaattggc tgttcttgcc gagaaacgaa
    87121 aagaagaagc gccagaaatt ggaaacatcg aatggctttc acctgaacag acatctcaag
    87181 cacttccgtt attgaaacca gcagtttcac tgcgtatcag tggtggtggt cgtctggatg
    87241 gaaaagcata tttagaacat cttggtcagc gtttagcaca aaaacaaatg gagcagatcc
    87301 aggcaaaagt cactttgcat aagaagagcg attcttggct catcaaggga ccgtttggag
    87361 aatacacagc tgatcgtgta attttgacac ctggcccggc acttaagcct ttattacaag
    87421 aattaggcta tgctgcagat atacgtccgc aaaaagggca gctcttagca tttcagacat
    87481 cttataagat gagtcaagac tggcctgttg ctatgcttga cggagaagct gatttcattc
    87541 ctttcatgga tggaaagatc cttttaggtg ctacccatga aaacgatcaa ggctgggatt
    87601 tggctcctac tagcgaagct tataagggat tgactaagag tacagaacag ttcttgactg
    87661 atccagatca gataaaaaac tggccatacg agttccgtgt aggtacccgt gcttatacgt
    87721 cagatttttc cccatttttc ggcgtactgc cagatgatcc aagcttactg gctgctagcg
    87781 gtctaggctc ttctggcttg accacaggtc cttatatcgg ctatctatta gccaacttct
    87841 taaatactgg tcattggcct acggaagatt atcaaaagga catctccacc tatattacga
    87901 aaaatccatc atagaaaaac agctttttca agtaaggatc ccgagcgata ttgcgcatgg
    87961 attacttctt gaaaaagctg ttattttagt tcaatttctg aatcaaattc tccaaacttt
    88021 cttttgcttc atctggcaag agatcttttc ctatctgagc ttcaatgaat cgtaaacgaa
    88081 tatcaagtcg ttgtttcacc agatttttat aggacgtatc ctcaaaagaa acaggaaaat
    88141 ctggtatagg taaatagtgg atgtcttcaa atggaccaaa cgacttgaat tctgccgttt
    88201 gttgcacgat tctttcaacg attgacaatg tcgtttcagg tttgattttt ttatcatcga
    88261 aatatccagt attcaggaca tagcaggctg tttgctgttt caaaaacaac tctcgaaaag
    88321 cttgatagtc ttccctaaga ggatagacac ggaaaggatt agcaaatggt tcaatgacta
    88381 gctcatctag ctgtcttttt gtagtgatat tttccgcgtc tgatcgtttt gttgctaatg
    88441 ttgcaccaaa agacgctgct aaaactgggt cattgatctt gataattggc ggaagcgaat
    88501 catctttcat gatccaaaaa acagcatcga tcttttcgct aagatgatcg actcggtcgg
    88561 gtgtcgcata acgtgatttg actgtccgcc catttccgtt tcgtatatct cctgttacta
    88621 ggactttttc tcctttactt gtacatgtca cgcccacatt ctgacaagta aggaaagaag
    88681 aaatggccgg atcatcagac ggatagtctt gtgttttatc aaagtaagaa ggttccaagg
    88741 cagtagcaaa accatttttt cgagaaataa cgaaagcatc gtcatgcaag atcgaaacag
    88801 agtgaccttc cgtatgtttt gctaaggtaa tcgttgattt tccagaaccg gacaacccaa
    88861 atacagccat cgtataggtc tggtcattac tagcatattg tttcatccca ccgtggcagg
    88921 caataaagcc attgcgattt cccaatgccc aagcaagcgt caaagtcgct ttttttaatt
    88981 ctccaaagta acgtaatcct agcacaaccg ctgtattatg gagagcatca aacaaaatga
    89041 gtccatttgg aaatgtttca tgtgtccatt cgggatcaca aaagatataa agatctccct
    89101 catcaaagga aacagacttt tgataagtct ctaagatctt cgaattcgct ggctgaaaat
    89161 tcagcaaata agaatacaaa ttgttctcaa atccttctgg aatcagcaaa tgactttgca
    89221 cagaaaattc ttcagatagg ccaacgatta cttttgtatg gtaaaactgg cgcttgcgac
    89281 tttgatacac agcttctctt aaaattttct cgtatttgct ttgttccttg tctaagtcct
    89341 caaagatccg ccgagcactt gctgttcttc ccacaatgct tccatcattg aatactagtg
    89401 tcctaacatc agctggtaaa tctagttctt cagcatgtga gattgttaaa tctgtgatga
    89461 tcgttcctgg actccctttt gctagttgat aagctgtctt cctatcaaaa acttcatgaa
    89521 cattattacc gtaaaatgtc gtttctacaa tcgatcgaat actggataac agtggatttc
    89581 cacttgtgat ttcgtttaat tcgagactct cttttgtact catggctcct cctcattccc
    89641 taaacaaaaa aacgttttct ttattataca ttattcgagt ttttatttgt actgctgcgc
    89701 tgtgggaagc aaacgagtta tttttcacac aaaaaaaccg agaacttgaa taaacaagtt
    89761 tctcggtttc atcattttcc ttttatcggc ttagtaccag ccgtttgcta accagaatgt
    89821 tttagcagca tcccatgaac cataacgaga tgttacatat tgttctgcta cacgttcttg
    89881 attggcagct gaatagtcgc cgtttaagta tgaagcatct aattgataac ggccgatgta
    89941 acgtccgtta gtagctgtgt atgaaccgcc tgattctttt tgtgcgatcc attcttttgc
    90001 agagcttgaa gttggcgctg ttgcagcagc tggggcagca ggagctactt caactgtttc
    90061 aacaggtgca acgtatgtat gttcttgcgt tgctgtttca gttgtagatg ctgtattttc
    90121 tgttgttttg ttttctgttg ttgctgaaga atcatttgaa gttgggattg ttaattgttc
    90181 accaacataa atgcggttga tgtttgcgat cgaatttttt tcagcaattg catcgatcat
    90241 tgagttgtct cctgcaaatt tttgtgagat cttagataat gaatcacctg attttactgt
    90301 ataaacttca tcagcgtgag catttgtagt tcctacaaac attgcagtag caccagcagc
    90361 aaaagttgta cctaaaacaa ttttcttaaa tgaattcata ttaaactcct ttttttctcc
    90421 gttttttatt ctttcgacgc tattaacttt atcatttaga aatatttcat aggtaaaaga
    90481 aacatgacat ttaatgacaa aataacgaat tatttaatat ttgtaacatt taaacaaata
    90541 tttttttgat acaaaaccat aaaagccttg ttgtataagc aaagtaatcg tttttctatg
    90601 ttttttttat ttttgaatga aaaacgcaga ttctgtaaca ttcactgcaa taatccataa
    90661 aaaaaagcaa aaaaattttt gatttttatc aaattctctt aaaaaaatgt aaaaaataca
    90721 aaaaaaccag taattgttac aacaattact ggacaaaaac tttgaataat gttaactatt
    90781 tttttatttt aactttctcc gcaataattt ctgggcatgt tccaattcgt ttataacgac
    90841 ttcttctgtt tctttagcta atatttcatc taatacatca agccattttt ccggttcttt
    90901 tgttcctaga cgtccaatag cccaagctgc tgttcctctg atgacagggc ggacatctgt
    90961 taaacattct gaaatctcag gcaatgccgt tcgatcacct agattagcta aagcaatcaa
    91021 tgcgtttctc tgcaaaggtt tcttcccacg ccatgaacca gctaaatgcc caaattgctg
    91081 tttgaagtct ttattagaca tcgaaagcat tggctttaat tttggatata tttcgtctac
    91141 ttttggttcc atctcttcat gaaaatgaaa atcttttcct tgattgtaag ggcagactaa
    91201 ctggcagata tcacatccat aaatgacatt tcgcattttt ttacgatatt cttccggcat
    91261 catccctttt gtctgagttt gataagacaa acatcgctgg gcattcattc ttccgtcacc
    91321 aagcaatgct tttgtcggac aagcagtcac gcagcgcata cagtcaccgc aaccaaattc
    91381 tcctggttta tcaggctcaa atacaatatt agtaacgatc tcaccaagat agacaaatga
    91441 accgaactct tcagtgatca acaatccgtt tcgtccaata aatcctaaac cagctcgctg
    91501 tgctacagcg acatcgatca gttctccagt atctacttgc ggagctagac gccattcctc
    91561 ttctttttgc catttttctg ctcttgtttg gatgaattcg atcaatcggt tcaaacggtc
    91621 tctgagtata tcatggtaat cgatccccca agaagcacga gcaaactgcc cgcgtttttc
    91681 atccctaggc acttcttcat ggatcctagt aggatacgca agtgcaatgg aaatgatcga
    91741 tttcggctga tcaaatgtca tttctggata aagacgctca tcgatatttg gatgttcaaa
    91801 gccagaagta tggccagctg ctttttgttc ttccaacgat tcttttaatg aatcaaaagg
    91861 ttccgccgtg gtgaacccga ttttgtcaat tcctaatcgt ttgctttctt gtatgatttc
    91921 ttcttttaat gtcatggtct tcctcgcttg ctgttaacgg ctgtataacc cataatatag
    91981 tttttctttt ttcagctgga caaactggat ctgctgatcg gcattcttct tttcttccat
    92041 ccattttttt cttgcagcaa atacttccca ataatttgtt gaaattaatt ttcttttgtt
    92101 atctaatgca ttaaaaaaat tcaatgaaac tggttttgta cttaacagtt catggagcct
    92161 tacctcttcc catggcgaaa actcagacag atcgcgggaa tacaatactt cttcatagag
    92221 atttttttgc tgtgtgtacg tgaatgtttg cgggattttc ccaggcctag caatttctac
    92281 tagacgatta taaaacatat tcattaattt gctgttggca ataaattgac ttttataata
    92341 ggccgactgg atctttttga ttactccttc tgctttgatg actgaaaata atgcaggcca
    92401 tgctttgacg gttatttcgt cgttttgttt aactaatacg ccaggtgtga agccgactgg
    92461 agaaaggaac acaaaataac cgataccggt attttcatct aaaggctgaa attcatcaaa
    92521 caaccatttg cctatgtaca gctcttcatc tggttctgtt gtctcatttt gatttgctat
    92581 gaataattta gctaattctg cttcaagaaa ttgaaggtct tgatccttgt cggtattttc
    92641 ctgctggctg atcaatcgaa agacttcttc tttaatcgta tatttatctt tacgtgtaaa
    92701 attcatagcc acaccttcct tccttactct aactataacg gaatttcttc aaaaaaggta
    92761 tctgtacgac gaaaaacagc ataatttttt ttcatatctc ttataaaaaa tgcaaggtct
    92821 gctcctcaag ctagaccttg cacttttcag ctttcttttg tttgtgacaa accttcatgg
    92881 atcgtttcaa tattccattt catcatctga tagtaagaat ctccttgttc tccttctttt
    92941 gctatggaat cagtgaacag tttatcatag attttcaaac ccgtttcttt tgctacccgt
    93001 tccatgcttc ttgagtctac actggtttcc acgaataaaa ccggtacttc ttttgctctt
    93061 atctgatcaa tgatcgcttt catttgatca ggcgtacctt gactttctgt attgatctcc
    93121 catatataag ctgctggcaa atcatatgct cgtgaaaaat acttgaatgc cccttcactt
    93181 gttactaata attttttgtt ctcttcgata gaagcaaaac tttccttcgc ttgtgtatct
    93241 aattctttta gtttttccac atatgcttct gcattttttt tatagagtgt cgcattttct
    93301 gcatcttttt cagagaatat acgtgcgatt tcctccacat attttattcc gttagatagg
    93361 tctagccaag catggggatc tgcttttgta tgttcttcac cgctagttaa ataaagaggt
    93421 tctacatttt tgctaactgc aaaataatct tttccttctt cttttttagc cgtttccatc
    93481 aagttatcga accagctgtt acctgtttca agattcaaac cgttgtataa aataacatct
    93541 gcatcgcttg cctttttgat gtcttctggt agtacttcat attcatgcgg atctgttccg
    93601 actggtacga tactgtggat atctatttga tctgttccga cctcttttgc catgtccgcc
    93661 aagatcgaat tggtagccac gactgacaac ttttctttac ttccttcatc cgcttggtca
    93721 gaagcctgct ttccgcaacc ggctaatacc aagaaactaa ctgccaagat taaaaagagt
    93781 gatttttttg ttttcatcta tctgcttcct ttctgaaata aaattccttt tgttggagaa
    93841 aataaaaaag caaggataaa aaatgcggta catgctaaca cgatcgtagc tcctgatggc
    93901 caattgtaac tataactgaa aaacacaccg acaactgcac ttagcatacc gattcctgca
    93961 gctgtaatga tcattttcag taaatggttc gttagcaagt aagccgtggc ggctggtgtg
    94021 atcaacatgg caatcaccaa gattgttcct actgtctgta aactgactac agccactaat
    94081 gtcaaaaaga acatcaaaag ataatggatc agcgatgtgt tcagcccata agcttttgcc
    94141 attgtcggat cgaatgatgt gatcttcaat tctttataaa agaaaaagac aaatatcaag
    94201 acgattccac taacgagtgc tgtcagcaac aaatcgcttt ccctaacagc taagacattc
    94261 ccaaataaaa tatgatacaa atctgtcgca ctctgggcat atgaaatcaa gataatccct
    94321 aatgcaaaaa aggagctaaa gacaattcca atcgctgtat catttttcaa tcggctccgc
    94381 tgagtcacga aaccaatcac tgctgctgtt agcatcccaa aagcagtggc tccaaagatg
    94441 taactaaaac caaacatata agaaatggct acacctggaa gaactgcgtg agagatagcg
    94501 tctcccatca aagacatccc tcgtaaaata ataaaagaac cgatgactcc agaagcaagt
    94561 cctacaagca tggaagtgac caaagcgtat tgcaggaatt gataattcat taatccatca
    94621 ataaaggatt ggatcatttt ttctctcctc cttttactaa atgtctgatg atctcaccat
    94681 aggccaattg aaggttcttc gatgtaaaga cttcttgtac tggaccggaa gcgatcagct
    94741 gtttatttaa aagaataacc tcatcgaaat attcttctac tttatgaaga tcatgatgga
    94801 cgatcaaaat cgtttttcct gaattcttca attcctgcaa gatgtcaaag atctttcgtt
    94861 cacttaacgc atcaatccct acgaatggtt catctaaaaa gatccattct gctccttggg
    94921 ctagagctct tgcaataaaa actctctgaa gctgtccacc cgatagttcg ctgatctgtc
    94981 ttttggcata ttcttccatc cctacttttt tcaaagcttg tcttgcacgt tctttttctt
    95041 ttttcccagg tctttgtcca attcgtaaag atggatatgt tcctaaaagt acaacgccta
    95101 atacatcaat tggaaaggaa agatccaatt cacttcgctg ttccacgtag gctatttttt
    95161 tacggactga gtttaccgac tgtccagaaa aggtgacttt accagtagta gctggtatca
    95221 actctagcaa agatttcata aatgttgatt ttcctgcacc gtttggtccg ataataccgg
    95281 taattttttg tggatttatc gtcaagttga tagttttcaa aacagttttc ccttgataag
    95341 cggctgaaag gtcttgaatt acaatggccg tacgttccaa atcttacact cctttttagg
    95401 tttacctaac tttttattta aatatagttt aactaaaatg gaaagcattt tcaagtagaa
    95461 tgatgaaaaa gtttttttcg aattttcctc gcattttatg aaaattttct gtagaatcac
    95521 atcaagagtt caataaggct aacctaataa tgaaaaacat gtgttgaaac gtttgattat
    95581 tttttcttgt tgactcaaca acgaaaggag tttttgtatg gaagaagaaa agttaactcg
    95641 aagtcttagt gcccgtcata tccaaatgat cgcactaggt ggaacgatcg gtgtcggtct
    95701 gtttatgggt gcctcctcaa ccatacgttg gacagggccc tcagtgatgg gagcctatgc
    95761 gattgcagga ttctttttgt atttgattat gcgtgcttta ggcgaaatgc tttacgttga
    95821 tccttcgact ggttcttttg caaattacgc gagcgagtac atccatcctg tggctggcta
    95881 cttgaccgct tggagtaata tttttcaata tattgtcgta ggaataagtg aagtgattgc
    95941 tgtaggatct tatatgaatt attggtggcc tgatttgccg gcaattattc ccggaatcat
    96001 tgtcgtcttg tttcttatgc tggcaaatct tatttctgtc aaggcgtttg gcgaattaga
    96061 attttggttt tcgatcatca aagtcataac gatcattttg atgatcattg caggtcttgg
    96121 ggtaatctta tttggatttg gtaatcatgg tcaggcagta gggatttcaa atctttggaa
    96181 aaatggtgga ttcttcactg gaggcgtcaa aggatttttc tttgcattat cgatcgttgt
    96241 tgcttcctat caaggaatcg aactgatcgg aatgactgct ggtgaagcag agaatcctaa
    96301 aaagacgatc attgaagctg tccagtccac tatcggtcga atcttgattt tttatattgg
    96361 tgctattttt atcattgtga gtatctatcc gtggaatcaa ttgagtgaga ttggttcacc
    96421 ttttgtacaa actttttcta aagtcggcat tacatttgct gcaggactga ttaattttgt
    96481 cgtgattaca gcggcattat caggttgcaa ttcagggatt ttcagcgcaa gtcgtatggt
    96541 ctatacactt gccataaatg gaaagatgtc taaaaaattt ctgaaactat ctcgtcacgg
    96601 tgcgcctttt tatcctgtcg tagcaatctc aggtggaatc ttaattggtc tgatcttaaa
    96661 ttatcttcta ccaatgttca tcaaccagtc agaaaatatt ttcgttttcg tatacagctc
    96721 aagtattttg cctggtatgg ttccttgggt agtgattttg atcagcgaga ttcgcttcaa
    96781 aaagaagcac gcagataaaa tgcatgatca tccttttaaa atgccactat ctccttatac
    96841 gaattatgtg acacttgctt ttttagctat cgtattgatt ttcatgttta tcaatcctga
    96901 aacgagaatc tcattgatta ttggactcgt tttcttgctt tacatgacga tccattactt
    96961 tgtacgcgaa aaaagaaccg gaaaataaaa aaagaacgaa gcttcacctt agtggaagct
    97021 tcgttctttt ttattgcttt tatcaattca attttagcgt ctcaccggga gtcaggaaat
    97081 aattctccat gctcatccca ttcagcgaca agatcgtttc tactggtacg ccagttcgtt
    97141 cggctatttg atttggacct tctccttcca aaactacggt tgtcgcagcc tgtgaagtcg
    97201 cgctgttggt attagtttca gaggaatctg ttgtgtcttg tgttgttcga gcttgcattt
    97261 cagaagcttc taccgactct gctgtctcag aatcagaaga tgttgtgtct tgtgtgcttg
    97321 ttgactctgc ttgaagagag gcgctagtct gcaaataaat atcggaaatc ttagcgacat
    97381 gattcgtata attagccgat aattgattga tcaaagtatc taagtctaca ccgtctttat
    97441 tttctgctgc ctgatacgct gcacgtaatt ttctgatccc ttcgtcggag attgcttgaa
    97501 gctcacgtgc tttttggtta gcaactgctg ataaaccagc tattccctct tgatttccct
    97561 gaatttctgt ctggtattct tcaatcaatg caggcgtctt ttcttcgatc tttttcgaat
    97621 aatcatttac gattgcttga agttgctctg gcaaaccatt tgctgttttt tcttcagaag
    97681 tttgtgtctc ttttgtttta gttgatgact cacttgtttg tttcgtctct gttttctttg
    97741 tcgttgtttc cgttatggtc gtacttttcg cttctgacga attttttcca tgaaaatata
    97801 gacccgcaac tcctcctgct atgatcaaaa acacggcaac tgctgcccca atcatgatca
    97861 tccgcttacg agctgcctgt ttttgctgtc ttcttcgggt catccgaaca ttttctcccc
    97921 actcattttc atcatacatt tttttcacca ccaattttta tgtataatag cgttatcaaa
    97981 cgcttcatat tcttattgta gcaaataatt gtcgctgtgc acatttttat ctttgttatt
    98041 tataagaaaa tttcaccagt tgagatgatt ccaagattgt ccgtcgattt ctccttgcag
    98101 ctgcattgtt cgttcgtcta tctcagccat cagtttcttt atttcatata agagcgcacg
    98161 gtcttgatat tctgattttt cgcttaattc atctaattgt tggatcagcc aatcatttgt
    98221 cataatgaag ttcctttcat ttcttgcagt gtaaaggtca agtcttcgat ctgctctttt
    98281 gcctcagtca gtgcttctac gatatatgct tgtttttcag attcttcttc ctgcattttc
    98341 tgattttcct gtactctttg aataaaccag tcaatccgct gagtcagcga tggtttgcct
    98401 tccaatgaga gatactgctg ataagcaatt agcttctccc aacgtttttc ctgggataaa
    98461 tacataaatt gtgctaaaac gaatggcgga agataggtca tatggaattt atttgcgatt
    98521 cgctgatacg gcctcaaaaa ttcggaaatc gtatattctt cttttcctcc agcttggtat
    98581 tctttttccg ccacacctgt tgtcaatacg attcctagtt ctttcccttt taatacatgt
    98641 gctgctcgtt ccaagacatt atcttgccaa atttttaaat gagcaggaga actataccag
    98701 taaaacggaa actggaaaat gatccgatca tgctgggcca agagctgtag ttcagtctct
    98761 atatctattt ttccgtctgg ataacttgat tccaaatgat gccaagtagc tggtaaacca
    98821 gcagaagctt ctttgaaaaa ttgctgattt aaagattctt cgatcgttgg atggctaatg
    98881 atgataagtg tacgcatccc ttttcctcct ttttagtctt cgctttacag tgtagcataa
    98941 ccgccacaag tttcttttgc cgatgcttgt cattttaacc agactaatca ggttgtccaa
    99001 gaaactgtgg tttgtttttc caactgtttt ttcaaggtat ccaaagcaat attcttaaaa
    99061 tttttgtttt tcatacgttt acgatagttc gtagccgttt ctccggtact ctttttgaac
    99121 attcggctaa atacgactag actattgaac cctacttgat aggcaatact ttccacggat
    99181 tcatccgtca gagaaagaag aaacgcccct cgattgatcc gtaccccgat caaatattcc
    99241 ttgatactgg tacccatatg atttttgaat actcgcaaca aatggctccg attgaccgct
    99301 aaatgctggg cgatttcctc aacagacaat ttttcagcat aatgtgcctc gatgtatttg
    99361 actgtttcaa cagctaaaga ggaatgaacc ttttgtacac caccgctgac ctttccgcca
    99421 tcttttaaaa ggactgataa aaaacggtag gttaatgctg ttaactgtaa ttcattttcc
    99481 aaggtttctt ccgtatcttt catgcattct aaaataatgt cgatatattt ttgtatgtca
    99541 gaagagacca tcgtgtattg gtcttctctg aaaagcgact gccgaatgat ttcttctgca
    99601 gcactcccac caaatgaaag ccagcaatac atccacggat cttctccatc tgataagtaa
    99661 aacgtcgagt ctcctggacg aatcaagaac agatcacctt ttttcaattg gaattgttga
    99721 tttttcacat gataagatcc tttgccttcc atcacgacat gcaggatgta atcattgcga
    99781 atagcaggac caaaagaatg aaacggcatc gttttagaga aaccacaaaa atcaaaatac
    99841 aattcttttt ctacttgttg atgttccttt tttaaaaaaa tcgattgctc cacgtctatc
    99901 cctccttact cctttagtat aatgcaacaa aaagttaaat aaaagtcaca gaaatatatt
    99961 aaaaaggaag cgatttcttg ttaagtttaa gtcattaaaa gatctttgtt attcgttgta
   100021 accggtttac ttagtattat atattgaaca ggagaggaat acagattatg aaaagcaaaa
   100081 tgatccaacg tgtgtcctac gctttaggcg cttttggaca cgacacattc tatgttacat
   100141 taagcactta ttttatggta ttcgtgacaa gccagatgtt cgcaggaaca gataaggcaa
   100201 cgaatgcaaa aatgattgct acagttacaa gcttagttgt aggtatccgc ttagttgaaa
   100261 ttatttttga tcctttgatt ggtggcatca tcgataatac tcgtacaaaa tacggtaaat
   100321 tcaaaccatg gttagttatc ggcggcgttg ttagttccgt actcttggta gcaatcttta
   100381 ccaatttctt tggcttagct actcataata cgactttatt tatcatatta tttgcaatcg
   100441 ttttcatctt attggatagt ttttattcat ttaaggatat cgctttttgg tcaatgattc
   100501 cagctttgag tacggaaaca aaggaacgtg aaaaatttgc tacgtttgct cgtttcggct
   100561 cttctctagg tgcaaatggt actactctag tcgttgtccc tatcgttact ttctttacct
   100621 atcttgttac tcataaacat attgaaggcg cttcaggctg gttctggttc ggtgtgattg
   100681 ctgctgttat ttcaggcggt actgcgatta tcactgcctt gggcacaaaa gaagtcgata
   100741 ctgcgatccg tcagcaaaat gaaaaagctg ggatcaaaga tgtgttcaaa gcagttgctc
   100801 aaaatgatca gttgatgtgg cttgcccttg cttatatcgc ttatgcgatt gccaatgcag
   100861 caacaactgc cgtattattc tacttcttca aatatgtact tggccaacca actgaatttt
   100921 ggatcgttgg tctagttgct gccttacttg gtttagtagc tgttccacta ttcccaatgc
   100981 ttacacgcgt catctctcgt cgctacgttt accttggagg gatcgcaatg atgatttctt
   101041 cttacttttc ctttacgatc gcaggttcaa gtttgccaat cgttatcatc gggctagtat
   101101 tgttctactt ccctcaacaa ttgattttct tatccgcttt gatgacgatc acagactctg
   101161 ttgaatatgg tcaatggaaa aatggtatcc gtaacgaagc tgttactcta tcaattcgcc
   101221 ctttactaga taaaatcgct ggtgctttgt ctaacgggat cgtagggttt gtcgctatcg
   101281 cttctgggat gactggtaat gctactgctg ctgatatcac tgctcatggc gtaacgactt
   101341 tcaaagctta tgcattctat gctcctgctg ctttgatgat tttctccgct attatttttg
   101401 cttggaagat tacattgaca gagaaaaaac atgcacaaat cgttgagaaa ttggaaaaca
   101461 aattggctcc agctgataca atggaagatg aacttcacga tgcagtagat ccttcccatt
   101521 aagaaaggat cttgaaaatg aagattacag aaaaagattt tggccaaggt tatcacttga
   101581 taaccttgga gaacaaaaac aagctagcac tttctatctc tgatttaggt gctagaatcg
   101641 tcagtttaaa atcaaatgat cgagaattag ttttgggatt tgacaccgct gaagaatata
   101701 tcgaaaaaga tccgtatatc ggtgcttcta tcggtcgcac cgcagggaga atcgaaaatg
   101761 gccacttttc tctcaatgga aaaacttacc aattagccac agatccaaaa actggacata
   101821 atctgcatgg tggtgctcct ggatttgaat taaaaaaatg gtcttatgtc attttgaatg
   101881 gcgaaaatga agcttctgtc atttttacta ctacaagtcc cgacggagaa catggttttc
   101941 caggtacaat ggatgtggaa atccgctata ctttgacaaa agataatatc tggcgagtga
   102001 cctctcgcgg caccagtgac caagatactt tattcaatcc gacaaatcat gtttacttca
   102061 acttgacggg agatgcttct cagtcaatcg atcaacatga gctttggctc aatagcgaag
   102121 cttatgctcc tttgcgaaca gatagtattc ctataggggt aaaagaaaat gctgcaggaa
   102181 gtgctttcga ttttcaaata cctaaaaaat tagcgtccgt ttttgctagt gatttggatc
   102241 aaaaaaatct tgttgacgga atcgatcatc catttttctt aaaagaaacc ggcttgggta
   102301 aagaagccgc tcgcttgact agccccgata aaagaatcca agtagatatt gctacagatg
   102361 cttctagtgt ggttattttc actgcaaatt tcggcacaga aacaccagaa atgcgcaacc
   102421 gaaaactggc acatcacggt ggcatcacat ttgagactca aacagctcca ggtgcagagc
   102481 gcttctcagc atttggttcg attcatttaa aagccggatc agtatttgaa acagtgacag
   102541 aattcaaaat caaaacaaga aaggaataac tcatcatgga aatcaaaaga agcttaaaca
   102601 caaaatttgc cgaaacattc ggacctaaaa aaactacaca atacttctca ccaggacgca
   102661 tcaatttgat tggtgaacac acagattaca atggaggcca tgtcttcccc gcttccatca
   102721 cttatggaac gcaaggtgta gcagcacctc gagacgataa taaaatatta gtttattcca
   102781 caaactttga cgatatcggt gtcattagtt ttactttaga tgagctagaa tatgataaaa
   102841 aagcaaactg ggcaaattac gtaaaaggaa tggtccttaa attaaaagaa gctggacact
   102901 caatcgatca tgggtttgag ttattagtgg aaggaacaat ccctaatggt gcaggacttt
   102961 ccagtagcgc ttcattagaa ttattagtag gtgttgtatt agaagatctg tttgatttaa
   103021 aaacagatcg cttggaacta gtccaaacag gtaaaaaagt agaaaatgaa ttcatcggtg
   103081 tcaattcagg tatcatggat cagtttgcca tcggcttcgg tgagctagat catgcaatct
   103141 tattagatac aaatacgctg aaatacgaaa tggttccagt gaaactagat ggttatgcaa
   103201 tcgtcatcat gaatacgaat aagcggcggg aattggcaga ttcaaaatac aatgaacgcc
   103261 gtagcgaatg cgaagaagcc ttggcacgtt tgcaaaaaac tttgcctatc tcttctttag
   103321 gagacttaga tgaagaagaa tttgaatcaa ctattgacca aatcggcgat gatacattga
   103381 tacgcagagc tcgccatgcc gtttctgaaa atcagcggac tttgaaggca aaagctgaat
   103441 tagaagctgg gaacttagaa gcatttggtc aactgttaaa tgattctcac cactctcttc
   103501 gctatgatta tgaagtaact gggatcgaat tagatacact agtagatgct gctcaaaaac
   103561 aagaaggtgt cttaggtgca cgaatgacag gagctggatt tggtggctgt gcgattgctc
   103621 ttgtcaaaga agaaaatata cctgccttca aaaacaatgt ctatgatgaa tacatgaaag
   103681 ttgtcggcta tgctccggaa ttttatgttg cacacattgg aaatgggaca acaaagatcg
   103741 atccagaagc tgttcatgtt tgataaaaaa atcaacgatc tcagctaaaa acaaatagat
   103801 aaaaataacc tctcagcaat ttccaaatgt gagccttttg ctcgtatttg aaaattgctg
   103861 ttttttattg acacggaaag agaacgtgtg ttctaattgt gttgaagagg tgattgttat
   103921 gtgggcgaat caaaatccgg tatttgttta tgaaaaagaa ccttcaagag atattttatg
   103981 tattgactgc aaatcttttt acgcctccgt agagtgcgtt gaaaaggatc ttgatcccct
   104041 tacaactaaa ttagtagtca tgtcctatcc gtccgattcg acagaaacac ggggtagcgg
   104101 attaatcttg gcttccagtc ctgcagcaaa aaaagcttac ggcatcacca atatcagccg
   104161 tgccagagat cttcccttcc cctatccaag tgatttatat attgttgccc caaggatggc
   104221 ctattatatg gaaaagaaca gagaaatcaa ttctatctat aaaaaatatg cagacgaagc
   104281 gaaccatcat gtctattccg tcgatgaaag cttccttgat gtaacaaata gcatggcact
   104341 ctttggtaaa acaaatgcgt acgacatggc taaactgatc cataaagatg tgtttgagca
   104401 gaccggaatc tacacgacta taggaattgg cgataacccg ctacttgcta aactagcctt
   104461 agacaatggc tcaaaagacg gaaagcaaat gtttgctgaa tggcgttatg aagatgtacc
   104521 agaaaagtta tggaaaatct cagatatcac tgacttttgg ggaatcggca aacgaacagc
   104581 aaaacgtctg aaacaaatgg gtatacattc tgtttatgat ttagctcacg cggattatta
   104641 tcacttgaaa agcaagctag gggtcatcgg tactcagctt tatgcccatg cttggggcat
   104701 cgatcgaagt tttttgggac aagaatatac accaaaatca aaaagtatcg gaaatagtca
   104761 aatcctagat agagattata caagacgaga agaaatcgag atcgttatca aagaaatggc
   104821 cgaccaagtc ggcactcgct tgagacgatc tgcagcaaaa acacaagtag tcagcttatg
   104881 ggtaggatac tctttaggct atcttgatcc aaatggcaag accgggtttc accagcaaat
   104941 gaaaatcgaa gcgacaaatg ctagcagaga tctagcagat gctttattga ccattttcca
   105001 ccagcattac cactaccagg atattcggcg tgtaggcgtg aactgttccg acctcgtata
   105061 cgcgacaggt ttacagctta acctttttga agatcctgaa aagcagataa atgaagcgaa
   105121 agttgatttt gttgtcgata cgattagaaa aaaatacggc tttcaatcaa tcatccatgc
   105181 gcatagtctc ttgcaaggag gacgcgccat cgcacgtagt tctctcgttg gcgggcatgc
   105241 aggtggtatg agtggattag aaggtggaaa agatgagacg gacagcaaaa aaattcattg
   105301 actataacga gtatcgagat cggccatttg gattaaaatg ggggactgct tttgcgatgg
   105361 aagaactagt caacggtatc aaaaaaaatg aagaagaagc acgcaaacag cctcttccta
   105421 aacaacaaat gacattgcaa gaaatcgata gtatactgac agaagccttt ttatctcgta
   105481 aagcagtaat cattcagctc aatttaaaag atgaatttgg aagactcttg gatgaggtcg
   105541 aagggcactt cattggtgaa gcctatgaag attactttat gattgaccat cagccgatat
   105601 tgtgggaaga cgtacggtat attgagttaa aggaaacaaa aaaatggttt gtgacatgag
   105661 aggttgtgac agaagtgatc aacttcaaaa aataagaaag gatttttcga aaattgcttc
   105721 ttaaattttt gtggaatttt ggcttatttt tcgaagaagc aacttctgga acaacgtata
   105781 ttagatatca gaggttgtga aaaagtcgct tagttttgag taacaagcca aggcgctgat
   105841 ttcacaacct ctgtctatct atccatctat tcggtaagat tcatgcatga cgtcttcttt
   105901 atttagtatg tagagccctt tttcttctga ccattcaaca taaatcagct gttttacatc
   105961 tgcatagcct tctttcttca agttctccat aagccatgct tcagtcaatt gattggactg
   106021 aagcacttta tgctgaattt gcccttcatc tacaagcagg atcgataaag ctttgtcttc
   106081 atctgatttt ttcaatacac tcatttgacc ggcattctct aggataacat gtttggcatt
   106141 ttcaagaaaa aagcattctt gctgtcttaa gattgctcgc aactgctcca tctcgatatg
   106201 gttatttgtc aactctgtca tgttgatgac gccgtctttg attagaacag atggctcgcc
   106261 tttgacccaa cgattgacct tttcattttt ttggacgata cgttcgatac cataaatcat
   106321 tactgcccaa agcgcaatgg caaataggac atgccctaca tggacattgt catcataggt
   106381 tgattcttct aagatcccac ctaaaacaag cgtatagact aaatcaaacg gtgtgatttc
   106441 tgacatggat ttcttcccaa gcaaacgtac cactaataat aaaccgatca acccgaacac
   106501 cagtttcatt gtaattgaaa aaatcatttt ttctccccct aactatctgt taattaaatt
   106561 atatatgctt tctcacgaac acgcatggaa tatacaagga agaaatgtat ccttttacta
   106621 aaaaaaggac tgtgacactg tagtgacccc caaaagttag acttttttgg agtggagaaa
   106681 tccactcctt ttttttatgc tctaaaatga tatttttaca caaccgttac ggttgtttta
   106741 cgaaattgga cg
//
LOCUS       DACBZK010000003        92615 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.003, whole genome shotgun sequence.
ACCESSION   DACBZK010000003 DACBZK010000000
VERSION     DACBZK010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 92615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..92615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.003"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            160..840
                     /locus_tag="IVD66_000237"
     CDS             160..840
                     /locus_tag="IVD66_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAP6144489.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            930..1964
                     /locus_tag="IVD66_000238"
     CDS             930..1964
                     /locus_tag="IVD66_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAP6144490.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            1978..2313
                     /locus_tag="IVD66_000239"
     CDS             1978..2313
                     /locus_tag="IVD66_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144491.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            2297..4777
                     /locus_tag="IVD66_000240"
     CDS             2297..4777
                     /locus_tag="IVD66_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144492.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            4833..6392
                     /locus_tag="IVD66_000241"
     CDS             4833..6392
                     /locus_tag="IVD66_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6144493.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            6389..7753
                     /locus_tag="IVD66_000242"
     CDS             6389..7753
                     /locus_tag="IVD66_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP6144494.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            7924..8994
                     /locus_tag="IVD66_000243"
     CDS             7924..8994
                     /locus_tag="IVD66_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6144495.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            9009..9677
                     /locus_tag="IVD66_000244"
     CDS             9009..9677
                     /locus_tag="IVD66_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6144496.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            9697..10275
                     /locus_tag="IVD66_000245"
     CDS             9697..10275
                     /locus_tag="IVD66_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6144497.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            10676..11587
                     /locus_tag="IVD66_000246"
     CDS             10676..11587
                     /locus_tag="IVD66_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP6144498.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(11965..12882)
                     /locus_tag="IVD66_000247"
     CDS             complement(11965..12882)
                     /locus_tag="IVD66_000247"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HAP6144499.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            13084..13521
                     /gene="zapA"
                     /locus_tag="IVD66_000248"
     CDS             13084..13521
                     /gene="zapA"
                     /locus_tag="IVD66_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HAP6144500.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            13579..14127
                     /locus_tag="IVD66_000249"
     CDS             13579..14127
                     /locus_tag="IVD66_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HAP6144501.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            14242..16602
                     /locus_tag="IVD66_000250"
     CDS             14242..16602
                     /locus_tag="IVD66_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAP6144502.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            16689..17003
                     /gene="trxA"
                     /locus_tag="IVD66_000251"
     CDS             16689..17003
                     /gene="trxA"
                     /locus_tag="IVD66_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAP6144503.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            17185..18963
                     /gene="uvrC"
                     /locus_tag="IVD66_000252"
     CDS             17185..18963
                     /gene="uvrC"
                     /locus_tag="IVD66_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HAP6144504.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            19108..20007
                     /locus_tag="IVD66_000253"
     CDS             19108..20007
                     /locus_tag="IVD66_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6144505.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            20000..21262
                     /locus_tag="IVD66_000254"
     CDS             20000..21262
                     /locus_tag="IVD66_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6144506.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            21423..23321
                     /locus_tag="IVD66_000255"
     CDS             21423..23321
                     /locus_tag="IVD66_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HAP6144507.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(23651..24370)
                     /locus_tag="IVD66_000256"
     CDS             complement(23651..24370)
                     /locus_tag="IVD66_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HAP6144508.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            24706..25038
                     /locus_tag="IVD66_000257"
     CDS             24706..25038
                     /locus_tag="IVD66_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144509.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            25025..27028
                     /locus_tag="IVD66_000258"
     CDS             25025..27028
                     /locus_tag="IVD66_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HAP6144510.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            27047..27517
                     /locus_tag="IVD66_000259"
     CDS             27047..27517
                     /locus_tag="IVD66_000259"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HAP6144511.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            27538..28122
                     /locus_tag="IVD66_000260"
     CDS             27538..28122
                     /locus_tag="IVD66_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HAP6144512.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            28137..29123
                     /locus_tag="IVD66_000261"
     CDS             28137..29123
                     /locus_tag="IVD66_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HAP6144513.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            29113..29424
                     /locus_tag="IVD66_000262"
     CDS             29113..29424
                     /locus_tag="IVD66_000262"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HAP6144514.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            29446..31227
                     /locus_tag="IVD66_000263"
     CDS             29446..31227
                     /locus_tag="IVD66_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HAP6144515.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            31220..32596
                     /locus_tag="IVD66_000264"
     CDS             31220..32596
                     /locus_tag="IVD66_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HAP6144516.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            32603..33238
                     /locus_tag="IVD66_000265"
     CDS             32603..33238
                     /locus_tag="IVD66_000265"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HAP6144517.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            33268..34623
                     /locus_tag="IVD66_000266"
     CDS             33268..34623
                     /locus_tag="IVD66_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HAP6144518.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(34815..36209)
                     /locus_tag="IVD66_000267"
     CDS             complement(34815..36209)
                     /locus_tag="IVD66_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAP6144519.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            36301..37272
                     /locus_tag="IVD66_000268"
     CDS             36301..37272
                     /locus_tag="IVD66_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAP6144520.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            37269..38051
                     /locus_tag="IVD66_000269"
     CDS             37269..38051
                     /locus_tag="IVD66_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HAP6144521.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(38220..38591)
                     /locus_tag="IVD66_000270"
     CDS             complement(38220..38591)
                     /locus_tag="IVD66_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAP6144522.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            38725..39168
                     /locus_tag="IVD66_000271"
     CDS             38725..39168
                     /locus_tag="IVD66_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAP6144523.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(39211..40020)
                     /gene="yidA"
                     /locus_tag="IVD66_000272"
     CDS             complement(39211..40020)
                     /gene="yidA"
                     /locus_tag="IVD66_000272"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HAP6144524.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(40039..41406)
                     /locus_tag="IVD66_000273"
     CDS             complement(40039..41406)
                     /locus_tag="IVD66_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP6144525.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEYIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(41390..42220)
                     /locus_tag="IVD66_000274"
     CDS             complement(41390..42220)
                     /locus_tag="IVD66_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HAP6144526.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            42383..42820
                     /locus_tag="IVD66_000275"
     CDS             42383..42820
                     /locus_tag="IVD66_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HAP6144527.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            42896..43516
                     /locus_tag="IVD66_000276"
     CDS             42896..43516
                     /locus_tag="IVD66_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HAP6144528.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            43705..44211
                     /locus_tag="IVD66_000277"
     CDS             43705..44211
                     /locus_tag="IVD66_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HAP6144529.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            44228..45127
                     /locus_tag="IVD66_000278"
     CDS             44228..45127
                     /locus_tag="IVD66_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HAP6144530.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            45214..46098
                     /locus_tag="IVD66_000279"
     CDS             45214..46098
                     /locus_tag="IVD66_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAP6144531.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(46290..46361)
                     /locus_tag="IVD66_000280"
     tRNA            complement(46290..46361)
                     /locus_tag="IVD66_000280"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(46326..46328),aa:Arg,seq:ccg)
     gene            46421..47755
                     /gene="rpoN"
                     /locus_tag="IVD66_000281"
     CDS             46421..47755
                     /gene="rpoN"
                     /locus_tag="IVD66_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HAP6144532.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            47958..48995
                     /locus_tag="IVD66_000282"
     CDS             47958..48995
                     /locus_tag="IVD66_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SorC family transcriptional regulator"
                     /protein_id="HAP6144533.1"
                     /translation="MLDEIKMIESVAPDIIEVLQERYKILRNIYWMQPIGRRSLSESM
                     GITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSLENFMDQLLGTHQTEQQLA
                     EYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEGENIIAVMGGTTMAVVAEQ
                     LSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKANGNHRALYVPEQLSLATYN
                     SLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEKELVMLKQANAVAESFGYF
                     FNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAIRAYMKNAPKQTWLITDEA
                     AANEILKGVTL"
     gene            49036..50037
                     /gene="gap"
                     /locus_tag="IVD66_000283"
     CDS             49036..50037
                     /gene="gap"
                     /locus_tag="IVD66_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAP6144534.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            50147..51337
                     /locus_tag="IVD66_000284"
     CDS             50147..51337
                     /locus_tag="IVD66_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HAP6144535.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            51441..52196
                     /locus_tag="IVD66_000285"
     CDS             51441..52196
                     /locus_tag="IVD66_000285"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HAP6144536.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            52312..53610
                     /gene="eno"
                     /locus_tag="IVD66_000286"
     CDS             52312..53610
                     /gene="eno"
                     /locus_tag="IVD66_000286"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HAP6144537.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            54010..55149
                     /locus_tag="IVD66_000287"
     CDS             54010..55149
                     /locus_tag="IVD66_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HAP6144538.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEELTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(55216..55791)
                     /locus_tag="IVD66_000288"
     CDS             complement(55216..55791)
                     /locus_tag="IVD66_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP6144539.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(55796..56770)
                     /locus_tag="IVD66_000289"
     CDS             complement(55796..56770)
                     /locus_tag="IVD66_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HAP6144540.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(56794..56838)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            57053..58021
                     /locus_tag="IVD66_000290"
     CDS             57053..58021
                     /locus_tag="IVD66_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP6144541.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            58134..58412
                     /locus_tag="IVD66_000291"
     CDS             58134..58412
                     /locus_tag="IVD66_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAP6144542.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCTYAKKEFEKKPEYQDVLRQS"
     gene            58530..58766
                     /gene="secG"
                     /locus_tag="IVD66_000292"
     CDS             58530..58766
                     /gene="secG"
                     /locus_tag="IVD66_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HAP6144543.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            58878..59624
                     /locus_tag="IVD66_000293"
     CDS             58878..59624
                     /locus_tag="IVD66_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP6144544.1"
                     /translation="MRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKADYTV
                     YAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFAVRA
                     LEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSLAEQ
                     QLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLRWYPE
                     SGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            59627..61984
                     /gene="rnr"
                     /locus_tag="IVD66_000294"
     CDS             59627..61984
                     /gene="rnr"
                     /locus_tag="IVD66_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HAP6144545.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWATELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            62006..62470
                     /gene="smpB"
                     /locus_tag="IVD66_000295"
     CDS             62006..62470
                     /gene="smpB"
                     /locus_tag="IVD66_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HAP6144546.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            62772..63491
                     /gene="atpB"
                     /locus_tag="IVD66_000296"
     CDS             62772..63491
                     /gene="atpB"
                     /locus_tag="IVD66_000296"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HAP6144547.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMVISLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            63544..63759
                     /gene="atpE"
                     /locus_tag="IVD66_000297"
     CDS             63544..63759
                     /gene="atpE"
                     /locus_tag="IVD66_000297"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HAP6144548.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVVALILVFGV"
     gene            63850..64374
                     /gene="atpF"
                     /locus_tag="IVD66_000298"
     CDS             63850..64374
                     /gene="atpF"
                     /locus_tag="IVD66_000298"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HAP6144549.1"
                     /translation="MLNQLAIAEVGNAMLGNVIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            64361..64903
                     /locus_tag="IVD66_000299"
     CDS             64361..64903
                     /locus_tag="IVD66_000299"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HAP6144550.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNKAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYAYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMNYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLENMRNQLNR"
     gene            64926..66482
                     /locus_tag="IVD66_000300"
     CDS             64926..66482
                     /locus_tag="IVD66_000300"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HAP6144551.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            66496..67398
                     /locus_tag="IVD66_000301"
     CDS             66496..67398
                     /locus_tag="IVD66_000301"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HAP6144552.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            67421..68827
                     /gene="atpD"
                     /locus_tag="IVD66_000302"
     CDS             67421..68827
                     /gene="atpD"
                     /locus_tag="IVD66_000302"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HAP6144553.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            68841..69263
                     /locus_tag="IVD66_000303"
     CDS             68841..69263
                     /locus_tag="IVD66_000303"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HAP6144554.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            69732..69962
                     /locus_tag="IVD66_000304"
     CDS             69732..69962
                     /locus_tag="IVD66_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HAP6144555.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            70059..71360
                     /gene="murA"
                     /locus_tag="IVD66_000305"
     CDS             70059..71360
                     /gene="murA"
                     /locus_tag="IVD66_000305"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAP6144556.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            71373..71549
                     /locus_tag="IVD66_000306"
     CDS             71373..71549
                     /locus_tag="IVD66_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAP6144557.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            71684..71980
                     /gene="yidD"
                     /locus_tag="IVD66_000307"
     CDS             71684..71980
                     /gene="yidD"
                     /locus_tag="IVD66_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HAP6144558.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            72164..72631
                     /locus_tag="IVD66_000308"
     CDS             72164..72631
                     /locus_tag="IVD66_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6144559.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            72716..73600
                     /locus_tag="IVD66_000309"
     CDS             72716..73600
                     /locus_tag="IVD66_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP6144560.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            73745..73951
                     /locus_tag="IVD66_000310"
     CDS             73745..73951
                     /locus_tag="IVD66_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HAP6144561.1"
                     /translation="MRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYGPKEYEIFFGE
                     EDFGKEKSLENAIETVIRHWNLHE"
     gene            74039..74119
                     /locus_tag="IVD66_000311"
     tRNA            74039..74119
                     /locus_tag="IVD66_000311"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:74073..74075,aa:Tyr,seq:gta)
     gene            74126..74197
                     /locus_tag="IVD66_000312"
     tRNA            74126..74197
                     /locus_tag="IVD66_000312"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:74158..74160,aa:Gln,seq:ttg)
     gene            74712..75419
                     /locus_tag="IVD66_000313"
     CDS             74712..75419
                     /locus_tag="IVD66_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6144562.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(75479..76123)
                     /locus_tag="IVD66_000314"
     CDS             complement(75479..76123)
                     /locus_tag="IVD66_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HAP6144563.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            76250..76537
                     /locus_tag="IVD66_000315"
     CDS             76250..76537
                     /locus_tag="IVD66_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144564.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            76645..76965
                     /locus_tag="IVD66_000316"
     CDS             76645..76965
                     /locus_tag="IVD66_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6144565.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            77046..78359
                     /locus_tag="IVD66_000317"
     CDS             77046..78359
                     /locus_tag="IVD66_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP6144566.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            78356..79075
                     /locus_tag="IVD66_000318"
     CDS             78356..79075
                     /locus_tag="IVD66_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HAP6144567.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            79203..79754
                     /gene="raiA"
                     /locus_tag="IVD66_000319"
     CDS             79203..79754
                     /gene="raiA"
                     /locus_tag="IVD66_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HAP6144568.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            79976..82510
                     /gene="secA"
                     /locus_tag="IVD66_000320"
     CDS             79976..82510
                     /gene="secA"
                     /locus_tag="IVD66_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HAP6144569.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPHHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKSFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            82636..83737
                     /gene="prfB"
                     /locus_tag="IVD66_000321"
     CDS             join(82636..82698,82700..83737)
                     /gene="prfB"
                     /locus_tag="IVD66_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078989099.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HAP6144570.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRGLFDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            83842..84528
                     /gene="ftsE"
                     /locus_tag="IVD66_000322"
     CDS             83842..84528
                     /gene="ftsE"
                     /locus_tag="IVD66_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HAP6144571.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            84512..85405
                     /locus_tag="IVD66_000323"
     CDS             84512..85405
                     /locus_tag="IVD66_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6144572.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            85557..87005
                     /gene="cls"
                     /locus_tag="IVD66_000324"
     CDS             85557..87005
                     /gene="cls"
                     /locus_tag="IVD66_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAP6144573.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWVLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            87342..88199
                     /locus_tag="IVD66_000325"
     CDS             87342..88199
                     /locus_tag="IVD66_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HAP6144574.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            88314..89234
                     /gene="pstC"
                     /locus_tag="IVD66_000326"
     CDS             88314..89234
                     /gene="pstC"
                     /locus_tag="IVD66_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HAP6144575.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            89234..90118
                     /gene="pstA"
                     /locus_tag="IVD66_000327"
     CDS             89234..90118
                     /gene="pstA"
                     /locus_tag="IVD66_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HAP6144576.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            90133..90939
                     /gene="pstB"
                     /locus_tag="IVD66_000328"
     CDS             90133..90939
                     /gene="pstB"
                     /locus_tag="IVD66_000328"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAP6144577.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            90955..91713
                     /locus_tag="IVD66_000329"
     CDS             90955..91713
                     /locus_tag="IVD66_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAP6144578.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            91726..92403
                     /gene="phoU"
                     /locus_tag="IVD66_000330"
     CDS             91726..92403
                     /gene="phoU"
                     /locus_tag="IVD66_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HAP6144579.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
BASE COUNT        30685 a        16128 c        19804 g        25998 t
ORIGIN      
        1 ttaataaaaa aggaagaata ttcatgtaaa cgattttatt gtttttttct cttttataca
       61 aaaagggtca taatttcaag taagcggatg aattcatgag gattttttgc atactgtctc
      121 tactatactt aggtcactaa gaaaaaggag tgatttatta tgaaaaagaa catgattggg
      181 acattattac tttcaacact tcttctaggc ggcttggcaa caccagcttt tgctgagggt
      241 caagcgactt caaaaggaga tattaccttt actgaaccaa caaataccgt ggagcctctt
      301 aaccctactg atccttcaaa accagtagag ccagcagatc cggaaaatcc agcaactggc
      361 cagacaggtc ctttaacact ggatgtagtt cccgaattgc catttggtac acacgagatt
      421 gaaagcggaa caaaaacgta tcaagtagac gcttcaaaaa acgatacacc ttatctccaa
      481 gtatcagatc gtcgaggtgt aggtgcagat ggccaagcac aagggtggaa cgtgacagtt
      541 tcggtttcag attttgtaaa cggttcacaa gttttgcaag gcgctgaatt agattttgga
      601 acatccactg ttaaaagtac gtcagataac gaatccactg gaccaactag tcaaactgta
      661 actgggttga gtaaagcaag tgcagcgaca ccaatattta cagcagcaaa agatcaaggt
      721 ctgggaacat ggctttctgt ttatgatcca gcaaatatca cactgaaagt gccgaaagca
      781 gcagctggaa cattcacggc tgatttgact tggaacctcg tggctggccc agtagcatag
      841 agtatgaaat aaattcaaca aactgcggtg aaaatactat aggtgaagga ttttttaccg
      901 cagttgttgt tgaaaggatg tggtggacaa tgaatcaaag taaacgactg tttgtttcgt
      961 ttttttctat tttaagtcta tttttcattt ttccgtcaat cagccaagca aaggattcag
     1021 caggagactt tggaatcaaa ccggtatttc cagagaacca aatagataaa gcaatcggtt
     1081 attttgattt attagtggca ccggaacaaa atcagacact agaagtaatt atcagcaatt
     1141 cttcagatga agaacgaaca tttgaggtct ctgtcaatcc ggcggtaacg agtgatggtg
     1201 gaacgatcga ttatagtcaa aaaaacccaa cgttagatga gacattgccg tttgatgtcc
     1261 gtgacgtttt gctcattgcg aaaaaggaaa tcaatgtatc agcacatgca gaaacaactg
     1321 tacctataga agtgaaaatc ccagcaaaaa gctttaaggg acgtgtatta gcgggtattc
     1381 atgtttcacc taaagaagaa gctgaaacag aaaatgctac agaaggagca caaatcaaaa
     1441 atcgtattgc ttataatctc gcagtcgttt tacaagaaag tcaagagacg atagaaccgg
     1501 atctgaaact tttatcagga gatttggacg aggtcaacgc aaagccaact gttcagcttc
     1561 gtttccaaaa tcctcagcct aggattatca gcaatttgat atttacgagc aagatctttt
     1621 atgaaaatca gctttatatt gaaaatacgt ctaatgcatt tttagttgca ccaaattcga
     1681 attttcactt gaatcttgat ttagctggtg ataaagcaaa agccggcgat taccgcgcag
     1741 aaatcatagc aaaatcaggc gacagtaatg aatggcgatt tacacaaaac tttacgatca
     1801 aaaaagaaaa agcacaaaaa gtaaatgaaa attccgtttt tgcagtacaa gaacaatctt
     1861 tcccatggct ttatgcagga ttggttgctg cagttctagt gttatggttg attttgctgt
     1921 ttttgtgggt ccacaagaaa aagaaaaaag gagaaacaac atgatgaggt gatttcgttg
     1981 aaaacatcga tcttattggg agggattatt gcaagtttgc tgttcttcag ctggcaagag
     2041 ccagtccaag cagataccaa aagttcaggt acgattacat tttatgatct aagtccaatt
     2101 ccgcatccaa gtggttcagt caatggcgca tcaaaacagc agacacagct accgatttat
     2161 aaagaatcta atcaacatgg cgtattcccg gagacgaatg aacaaaagat ccgttttctt
     2221 tatttgatca ttggtataga attatggctt cttgcgtggt tgttgttatg gagaagaaag
     2281 gaaaaggagg atgaacatgt tgctacaaaa taaattttca ttttttcgct ccttcttttt
     2341 tacttcgctt tttgttttaa gtatatttat cttttcacct tcggcagaag ctgttggagc
     2401 aacgcctcct gccatttctt atgatccata cacgtatgaa aatatcgtac ctccaaatgg
     2461 tggacgtagt gcagtcaatg gcgggaagct tgtccaacta actggggcta accaattgcc
     2521 taaattgact gctacttatt tgaacgatgg ttcaaatgat ccttggaaag gtggcacggt
     2581 ccgttttcat tgggaaagcc atgtgaaact aacaaatgta cttgatttgg tgaatatcac
     2641 tgcacaagga tttgcatttg tggcgatcat caatttgccg gaacatgtat caagcagtga
     2701 tgtattaaaa gcaattgact ggaacaacgc ctacttgtat attgccggtg cccccatcaa
     2761 ggttactagc ggaagtttat tatcagcagg aagccatacc ttgcgttttg ggatggggtc
     2821 gtgggataca aatactctat tgacagatat tattgctatt attacgcgag gcgaattcaa
     2881 cgtggacgat atcccgcttc aatttgatgt tacagctaat gtcgcgaaga tgacagaaaa
     2941 cggagataaa tatgatacga gtccaaacaa aattttgacc aagggtaaat tacaaccttc
     3001 tatgtctaaa aaggccgttt tttctgttga tttttatgat tcgaataata ttatccaaga
     3061 tcgtatgttc aattcgattt tagctccagc tgcaggtaga ttttatccta aattaactgg
     3121 cggaaacttg aatccaggag catatgcatt ttctgcaagt gcagagataa atacgtggaa
     3181 tagttacatc tcaccaagtg attcaacagg aaaatataat acatttgctg ataccacaga
     3241 atacgtggat ggaaataacc agaaccttcc aggctctacc aatagtcgga cattgacgat
     3301 ggggctgact gaaggacgtt ttgatcagtt gccatttagt cgctttgatc gcgtagtcaa
     3361 ctattttaca ggaaaaaacg ttacacaagg agcaatactg actcatactc cagcaagcac
     3421 aagtggattg aatcagacag ccaatatcgt gtacagtggg aaagatgcgc aaggcggatt
     3481 gctttctcct gttgctttaa aggtattgga gcagtacaag ctagacggaa cggttttacc
     3541 aacaaactta acagccgata gtcagtgggg aaagctcctt tcttctgcat cgtaccaagt
     3601 cacggccaat tggtcagcaa ctgaactaaa aaagggttcg atccattaca ggctttattc
     3661 gaaaggaacc caaaaattag cgacaggatg gacagatcaa cttttccaaa cgatccaatc
     3721 aaataacggg ggtgtaaata cagctacttc tacactacct gcattggctt cagggcaata
     3781 ttattttgat tatcgcttgg tggacgatgt acttactaac atgtatccgt cttttgcgta
     3841 caaatggcag tctgaacaag ctggaatcac cactcttcct caaataacag tggctaattt
     3901 tccatctgtg agtgcagata gtcagctaaa aaaccttagc agacaacctg agacaggaga
     3961 tcccctgtct gctctatcag gagatacgat tcaagaaaat gtgacattca cgttaacaaa
     4021 atctggggat gcgataaccg acaaaaaaat cacgatctca cttcctgaaa atactactta
     4081 tatcaatggt tccttaaaat taaatggtac aactatcgca gataccggca ttcaacaagg
     4141 agtttctgtc ccagcagatc tattgagcaa aataggagat accattcatc ttacttacaa
     4201 ctatcaatta aatactgtag atacttcttt acaatccgtc agcatactga caaaggcagc
     4261 tgtactttcc agcaatatta cattagcaga tggtgctaag cttcctaacc cagttgtcca
     4321 aacatctgct aaaacaattc ttgtccccaa acaagaatta acattagtta atgtaccaga
     4381 tgattttaca tttggtaacg atctccccaa accgttgaag acaagttatt atgaatcaaa
     4441 aggcgatttt tcttttgatg tgcgggatac tcggcttcca agcacgtctc cttggcaact
     4501 gacaggtaca ttgacttctt tatttaagaa tgatcaaggt caagaattaa gcggaacaaa
     4561 attatacttc aatcattctg gatcaaagca attgattcag caaggtcaaa acacgttgat
     4621 ttatgagagt gatggaacag ctaaaggaga ggttctcgtt gactttcccg ataccgatgg
     4681 tttactctta gaggtaaata gcagtacgaa tgctcaacct ggcgcaacgt atcaaggcat
     4741 ggtcacatgg gaactgacag ctgggccaac cagctaagtg attagaattt gtatggatct
     4801 gtgataactg tcacagatcc tctttttcaa ggatgagaag gaaacttctg ctgttaaaat
     4861 cagaaatgct tgaaggagtg gacttggaac ttttcagttt gcttgaaaaa aatgaacaac
     4921 ggcaaatcaa acttttccaa cttttattag aggaaaaagg agaggtttcc gttaataacg
     4981 tacttacccg cttatcagtt gatcgggcta ccttgaaaga agatctgttt tatttacaag
     5041 ctaacttgga aaatatcaaa caattggaaa ttgttatcca agaagggaat attttattaa
     5101 tcagacatgg aaatatagca gcagtcgatg tttattatca ttgttacttg cgctattcta
     5161 caaaatatca gatacttctt tatctgttgg aaaatggctc atttgatcgg cagaaacttg
     5221 tcatggaact taatatcagt tcggctactt tgtctcgcag agtgaaggaa ttaaatgatt
     5281 ctttaaatga gtttcatctg aaaataaaaa gcgggcggct gaccggtcca gaaagtcaaa
     5341 ttcgttattt ttatttccaa ttattttggt ttggacgtcc ctatcttgaa aacaaaaaag
     5401 aatacagtga tttatcagga aacacttttt tagatctgct gcaaaaagag tttagttttg
     5461 ctattacaga agaaggacga ttgaaatttg aaatatggct ttccattatg aagaagcgaa
     5521 tgcgctgtac gaaaaaatcc aaaccagatt atagcaatct tcctgttgga ttgtttcaaa
     5581 cgacacaatt tttattggac ctccatacat ttttgacccg ttacttcttt caatatgcct
     5641 ttccttggaa tcaaaatgaa acgttggttt tttatctttt catgatcagt aactttacat
     5701 tagatacaca taactcgcat gtccaggagt ttttgataag cgaaaaatac aaagacgacg
     5761 tagtagctca attgaatcga acgtttaaac aatcgataga agaatatttc tctttttatg
     5821 tttttccaga agagatttcg caaaagattg cgttgacagt gatgcaaaat cacgctcatt
     5881 ttgcctattt tagaggatgg atgaatattt ttggccaaga aggattaaaa cagcggttaa
     5941 ctgaagtaga agataaacaa ttcctggttt tatgtgaaag attggtcaga caaacatttg
     6001 ctattgttga ttttactgaa gtagacgagg aaaatgcccg ctttgaatta tttgctcgct
     6061 atgcatctat tttacggacg ctgatcaagc agttagaatt acgtctgcaa attgcttatg
     6121 atcttcctta tgaaaggcta atggcggata tcgtgaaaga aatcatccag gaacaattgc
     6181 tgaatacgat caaatatgat ttagtcgaat acgagaaaga aaagcagtat gatatcattt
     6241 tgactagcca attgaaagag tacccgtcac agaagtccgc taaagttttt gtattcacta
     6301 gcaacgaata taattatgat ttcccctatt tgaaccaatt tttaaaagaa tgttatttag
     6361 aaaaattgaa tttaaggatg aataaaacat gaaaatcgtg atcattggtg cttcccatga
     6421 aggcatcaca gctgccctaa atctaagaaa acttcaaccg aaagcagaag ttttactgat
     6481 cgatgaagat cataaagatg gactaggcta tgtttcaaat ggaatcaacc tttatttaaa
     6541 aggaaagata cgtagtttag ctgaagttgc ccataacatg cggactcttc aagaaagtgg
     6601 ggcaaaactg atcaccgaat ggagagtaac tgaacttgat ccagacaaac atcagctcat
     6661 cctcgcatcc aaagaaggaa aaaacgagac cataacctat gataaattaa tcgtagcgac
     6721 aggttcctct cctgtcacct tgtataaaca aattgaagct gaaaatgtct acacctataa
     6781 aaatctagtg caatctaagc aagtacttgc cgctttaaaa gaagcaaaag aagtagtgat
     6841 cttcggtgct ggttacattg gattggaatt agcagatgct ttgagaaata aaggatacat
     6901 tattcatcta gttgattata tgccgaatgt tttatcaaga tatttcgata aggatatgat
     6961 caacagtttt caaaatcagc tgcaaactaa gcaaataaat ttttatccaa atgaattctt
     7021 gatcgattgg aaaaaatcag aagagaaagt agtatccgta caacttctgt ctcaaacaat
     7081 aaaggcagat atggtcattt tttctgccca aactcgtcct aatacgacat tgttaaaaga
     7141 aaaagtggct ttgtatgagg atgagactgt gatagtcaat gaatatctgc agacaagtga
     7201 tccggacatc tatgcgattg gagatatcgt cccagtcagt tttgacaaaa ataaacggca
     7261 tctcttttta cctttagtta ctcgagctgt acatatggca agagcagtag cgctaacttt
     7321 gagtggtcag ccaaccgctt acgacctcag acaaaagata acagcagcag tcattataga
     7381 ctacttttta ggaactgtag ggctgacaga agatgaagcg ccattcttgg aacaaaatac
     7441 cggttcgtgt tcaggagaat ttgatctatt tccacaatac gacgaagaaa acaaaacagt
     7501 aaatgcaaag ctgatctacc atccggatac attagaaata attggcggac agctgataag
     7561 ccaagaattc ttattatcag atttgaacct gcttgcggat atcgtgaaac acaaaactac
     7621 gattccacag ctagcagttg aggattttgg atttctgtct gaatacacct ctcgttttca
     7681 ctacctcaat gagttagctt ttaaagtact agctaagaga gcaaatagca atagagtaga
     7741 taaaagactg tgagaaatat cacggtcttt tattgtgtgg ggatataata aatattaatc
     7801 aatcgagaat aaaaaattca tataatgaaa tagcggaaga attttttgag cataatattc
     7861 gccaaaaatt tatcaagtga taaaattgtt gtataaaatg attatttcag gaggaggagt
     7921 taaatgtttt tagcattaaa tgaaattatg cattcaaagt tacgttatgc gttagttgca
     7981 ggggtgatgt ttttgatcgc ctacctggta ttttttttga ctgggttagc ttatggctta
     8041 gctcaagata atcgaacagc agtcgacaag tgggaggcag attcgattgt gctttcgaaa
     8101 gatgcaaatt caaatctagg gatgtccatg attactaaga agatagcaga agaagtcgaa
     8161 ggtgggaaag tggcgtatct tgcccaaaca cctggagtcg tgactagtaa agacagtaca
     8221 gaagaaggaa aaatcaatgt tagcttcttc ggtatcgata aaaatcaatt catcatgccc
     8281 aatcttgttg aaggaaaagc ttttgataac gatgatgagg cagtaggcga tattagtttg
     8341 aaagaagaat atggtctagc cataggagat acagttaagt tatctggtag tgacaagacg
     8401 tttaaactaa ctggctttac ggatcatgcc aaattcaatg tctcaccagt tctctataca
     8461 accatcaatg cttaccaaga aatccgcttc gaaaaagaag atacaagtga aaatgcacgg
     8521 attaacgcaa tagttgtcag aggtaaaatc agtaatttac ctgaagattt agaacagatc
     8581 aaaatttcta aattcatcaa tgaattacct ggatataatg cgcaagtatt gacttttgga
     8641 tttatgatcg gatttttgat cgttattgcg gctattgtga tcgggatttt catttatgta
     8701 ctgacgatgc aaaagattaa tatctttggt gtaatgaaag cacaagggat cacaggagga
     8761 tttattgcgc gttctgtagt ggcacaaaca ttcattttat catttgttgg tattcttctt
     8821 ggtctattag gaacagtggg aacatccctt gttctacctg atgcggttcc attccaaagc
     8881 aattggctgt tttttggcgt cattagcttg ttgatgttag tagtagctgt gttaggcgca
     8941 ctattttctg ttcggacaat cgtaaaaatc gatccgttga aggcaattgg ataagaagga
     9001 ggaagaacat gaaagcaata gaatttaaag aagtagaaaa aagtttccaa gatggcgacc
     9061 aagtagttaa agcattgaaa gaaacaacca tgagtatcga taaaggggaa tttgttgcaa
     9121 tcatcggtcc ttctggttca ggtaaaagta cttttttgac tttggcaggc ggattgcaga
     9181 cgcctagcag tggctctgta tttatcaatg atcaagaatt cagtaatcaa aaagaaagcg
     9241 aacgcgttaa actacgtttt aaagaaattg gctttatttt gcaagcttcc aatctggttc
     9301 cttttctgac agtaaaaaag cagttattat tagtagataa gattaaacat gaacatcgtc
     9361 aaaaagaagc aaacgaatta tttgagcagc ttggcgtgga taagttgatc aacaagtatc
     9421 cagaagaact atctggtgga gaacggcaaa gggtcgcaat cgctcgtgca ttgtacaatg
     9481 atccgtccat tattctagca gatgaaccaa ctgctagttt ggattcagaa aaggcacgag
     9541 aagtagtcga tatcttggca aaagaatcaa aagacaaaaa taaagcaacg atcatggtta
     9601 ctcacgatac acggctgatt gacaaatgcg atagaatatt tatgatggaa gatggtgtat
     9661 tgaaagaaaa agaataacca aaaagcaggt ggaaaaatgg tccatcgata caacaaagat
     9721 acacagcaaa aaattttgaa agaagcgact gacttgttta tgtccaaggg atatctcggc
     9781 acttcaacaa gagaaatcgc acaaaaagtt gggatcaccc agcccaatct ctatcattat
     9841 ttcggtgata aagaaaaact atatacggca gttttagaaa accacttaaa agatgttgga
     9901 aaagctttga gagaaatcgt tcaaacaagc gaaacgggat ttcaagtaac cttgacaaaa
     9961 atggcgcagt ttttgattga gacacatctg gtcgatttgt ttctgatgct tcacgatctt
    10021 gaaagcaatc tttcaaagga aacaagagat catcttttct ttctatggaa gaaaaattat
    10081 cgtgaacctt ttgaagaaat cttttcagca aaccaatctg tgctaagaaa tgggatttca
    10141 aaagaaatcg cagcaaggca ttttttctta gtgttagcac cttacatcac tcggtcgaaa
    10201 agacctgtgg aagaaccgct aaatgtggcg caattgatcg atttatattt gaatggtgta
    10261 ttaggagaag cgtaaagctg ttatataggg agaaaatagt taggtgaaga agcaagatat
    10321 gacgaagatc gttatatctt gcttctttat ataggtagtt tttcataaat acaaatttgt
    10381 tattctctca tgattatcag ggtatatttt tatttattat gtcggtgttc caggaagtgt
    10441 tttaatttaa taacgaagaa attaattgtt tgtagaatga aggaaactat ttattgggta
    10501 gatgaatcac cacgaatagt caaaaggaga tttcaggata tgccaaaaat gaaaaaaatc
    10561 attttagcag taatgttatt ttctacggtt atatctttta cagccccttt tttgcttact
    10621 taagctgatt ttaagttttg gcccttagtc tggatctacg aggtgagagt caagaatgaa
    10681 aaaaataatt ggagcttttg tatttgcaat cattatcatt attatctgtt ttcaaataga
    10741 tgtttttggt caaaaaaaga tagttggaca aacggtcagc agtacgaaca gtacggttac
    10801 aaagacaaag gaatcatttg atgatacaga acaagagaca ttaatcaaaa tcggaaaaaa
    10861 tgaccgtaca ctatatacag atgactcgct aactacccca cttgcaacta taaacggcgg
    10921 agagctggcg gagtttcttt ctgaaacaaa aaatgcttat cagatcaaga caaatgatgg
    10981 ctatactgga tatttagccc tcgaagatgg aaccaaagtc acaaagaata tacaaacaaa
    11041 accggaagag ctatctgatg cagtgattgt attagatcct gggcatggcg gaaatgatac
    11101 tggggcatta agcaatgatg aacaaacaga agaaaaagat ataacattaa gtacagccat
    11161 aaaagtaaaa aaggcgctag aggatgctgg agcaacggtt tatttgaccc atactacaga
    11221 tgaattagta cagcttggag atatatgcga ctacagtgaa gaaaaaaagg cagatgtctt
    11281 tatcagttta cacgcagact ctacggaata tgcgaatgaa gcaactggaa tcacgacata
    11341 ttattactat ggacaagagg aaacattagc acagacaatt gctgactcct tcactgatct
    11401 gcctctggat tcaagaggaa tctccactgg gaactatcaa gttcttcgag aaaatcttca
    11461 accttctatt ttaatcgaga tgggttatat gaataatgat agtgatttaa aggaattagt
    11521 aacagacagt tatcagcagc agattgctgc aagtttgaca caagcattga ccacttattt
    11581 tcagtaataa ataagcccag ccaaacaaaa atagctcctc atatttttcg tttggccggg
    11641 cttattatcg cagatgcaag cttttaaaca ccgtttaagg aagaggtcgt gagcctgccg
    11701 ttcaactctg agtcacaagg agcaatttca aaaaacagct tctcatgttt gatgactatt
    11761 gtgacttgtg accgaggagt tggcatgaga acaccgttta agaaaaaggt tgtgaaatca
    11821 acgttttgtt ctgagtatta gagaaacaaa cggaaaaata gttcctcata ttttgccgtt
    11881 tgttgagcta ataccgagga tcagatgatt gaacaccgtt tattcggaac aagggactgt
    11941 gacatgactt ttgtcacagt tccattattt ttttagtagc ttcaaagctt tttctgtatt
    12001 ggcaaaatga agtttggcat atttttcaag cataggcatg ccgcctttct ccaatagttt
    12061 tgccgctact tggtcagatt tcgttccagc tcctgacgga agggtgattc cagcttcagc
    12121 tgatgctttg tctaactctt ccaaaaagct ggcacgactg atgatagaag cagcagcaac
    12181 agctaaatga tattgttctc ctttagtaac gaagtacagt ttttcttgta attgattttt
    12241 ttctaaacgc gcatattttt taaaatttgc ttccggcgta aactgatcga tcaaaatcgc
    12301 ttctggtttt tctggctcga ttttttttag cagcaaatgg atcgcttgat tgtgcaaagc
    12361 gactttcatc cgaacggcat tgtattttgg ttggatctca ttgtattttt ctggagataa
    12421 gacaagcagt ttatagggga tggttttttt taagatgtca gcaagctgga tgatttggct
    12481 atcttttaac tcttttgaat ctctaacacc aagtttacgt aattctgcaa gctgatcacg
    12541 tttcacataa gcagcacata ctgttagcgg accgaaatag ctgccatttc cgacctcatc
    12601 actacctaaa acggataatt gactgatatt ttttggcaaa gaagaggctg tttttgctgg
    12661 cttggcttgt ttatcctgtg cctcccccca tttatcagct tctattgctg cattcgtacc
    12721 ttgaaacatc acttttccgg atgtataagc ggtaatggtc gtcccgtctt tttttgcagc
    12781 aaagctagta taaggaatct gtttatttaa caaataagag cgatagtatg ctttcatttg
    12841 actaagttgg tcgtttgttg ctttgataat gacgttgctc ataaaattct cctcgttttt
    12901 atacataaaa ctataccgca actcacgact tttcgttttc taagagattg cgagacatag
    12961 cattttttta aagtttatca tataatagtt aagtatgtga aaaatatttg tggagaacgg
    13021 tgaaagaacc aacttcatgg tacactaaat aaaactttca tcaaatagga ggaaatgatt
    13081 cgtatggcgc acgaaaaaac acgctacaaa gcggtgattg ccaaccaaac atatactatt
    13141 atcggacggg aaaccaagca tcatatggat atcgtaacga agctgatcaa tgaacagtta
    13201 gcagaattga aacaattatc accacaaatg gataatgaac aagcagcaat cttgatggct
    13261 gtcaatgcgc tttcggatca attgaagaaa caagaaagaa tattggagct ggaagaagaa
    13321 acagcagaat taaagaaaaa aatgatcaaa tttacagagc ttgaaaatcg tgtgaaacgc
    13381 attgaagcaa tcgagaacga agctcgggaa gtattgaaag aaaatggtca agcagatcat
    13441 accattaaaa atcatgtgga agcacaacag attttaaacg agaaacgaaa aggacaaatt
    13501 aaacaaaaat cttctaatta agatcctttt atcaaaataa gaaaaattta aaaaagttag
    13561 aagagaaagg aacgtagcat gctgagtttg ctgattttat ttttattgct aattgcgttt
    13621 ttttctggag cacgtcgcgg gtttgctttg caaatcatat tcgcgattgg atatgtattg
    13681 tcatttattg ctgcccagca tttttacaaa ccattagcaa gtcatttgga attatacatt
    13741 ccatacccag ctgtcacccc aacatcaaag ttagcatttt ttgatcaggt atttgccttt
    13801 cacctagatg aagcttttta tgcaggaact gcttttctga ttattttgct aattggctgg
    13861 ctgcttaccc gatttgtggg ggtttttgtc catggattga cgtatgtgcc gatcttgaga
    13921 caggtagact ggattgcagg aggcatcctg tcactaatca tggcttacgt tactatattt
    13981 ttgattttgc agttacttgc ctttgttcca ttagatgtgg tccaaaatca attcggcgag
    14041 catagtttcg ctcgttttat cgttgagaga acgccatttc ttaccaacaa gatgtatgag
    14101 ctttgggtaa cgaatatttt gaattaagga aaatagtgct ggaaaatatt tcgttttttg
    14161 tacagagtag tttatttaag aaggctgcgt agcgtatgtc cggcacagct cttttttcat
    14221 agtgaaagat aaggtgataa aatgaataac cgaatccttg aaacattgga atttgaaaaa
    14281 gtcaaacaga tggtcagaca atttgtagtg actgcacaag gaaaagaaga actggcagaa
    14341 ttggtaccag tgagtgagaa acaaacgatc acaaactggc ttcaagaaac tgaggatgga
    14401 ttgaaagtgc aacgtctgcg aggcgggatc cctataccta aaattgaaaa tatccgtccc
    14461 catatgaaac ggattgagat cggagcagac ttgaatggag tggagcttgc acaagtttcc
    14521 agagtattgt ctacgacaag cgaattgaat cgtttcattg atgatctttc tgacagtgaa
    14581 atcgaatttg cacgtttgta tatgtgggca gatcagttag tcacgatccc tgttttgagc
    14641 cgccgtttaa aggaagcaat cgatgaagac ggacgcgtga ctgatgacgc ttctcctgag
    14701 ttaaagagca taagacagaa cattcggcga agtgaacaag ctgttcgtga acagttagat
    14761 gggatcgtcc gtgggaaaaa tgcaaagtat ttaagtgatg cgatcatcac catgcgaaat
    14821 gaccgctacg ttatcccagt caaacaagaa taccgcggtg tatttggcgg tgtagtccac
    14881 gatcaaagtg cttcaggtca gactttattt attgaaccaa aacaagtggt ggatttgaat
    14941 aatcgtttgc gtcaatacca aatcgctgaa cgaaatgaga ttcaacgtat tttaagtgaa
    15001 ctttctgctg aacttgttcc ccatcgtcaa gaaatcatcc acaatactta tgtgattggt
    15061 aaaatggatc tgatgaatgc aaaagcacga tttggtaaag aagtaaaagc catcgtgccg
    15121 ggaatcagtg aagacaatca tgtcgtcttg aaacaagcaa gacatccact gatcgatcag
    15181 gaaaaagtag tttctaatga catcacaatc ggaaaagact atcaagccat cgtcattaca
    15241 ggacctaaca caggtgggaa aacgatcacg ttgaagactt taggtctgtt acaactgatg
    15301 gggcaagcag gattaccgat tcctgcaggt gaagaaagtc aaatcggtat ttttgaggaa
    15361 gtatttgcgg atataggaga cgaacagtcg attgagcaaa gtctatcgac cttttcttct
    15421 catatgacga acactgtaga tattttatca aaagtcaatg aaaaaagtct ggtattattt
    15481 gacgagctcg gtgcaggaac agatccgcaa gaaggtgctg ctctagcaat cgcaatctta
    15541 gatgatcttg gtaaaaagtc tgcttatgtg atggcaacaa cgcattatcc tgaattgaaa
    15601 gtttatggat ataatcgggc aaatacgatt aatgccagca tggagtttga tgtggataca
    15661 ttaagtccaa cgtatcgttt gctgattggc gttcctggac gaagcaatgc gtttgaaatc
    15721 tctagccgat taggtcttga tacagaagtt attgatgaag cgaagcagtt gatgaatgat
    15781 gagagccaag atttaaacga aatgatcaca gatttagaga atcgccggaa aatggcagag
    15841 accgaatatc tggaaatgcg tcattttgtt tctgaggcac aagaacttca cgatgatttg
    15901 aaagaagctt acagctattt ctttgaagaa cgtgaaaaag aaatggaaaa agcaaagaaa
    15961 aaagcaaatg aagtcgtgtc agaggcggaa gaaaaagcag aaaaaatcat tgctgatatt
    16021 cgtaaaatgc aacagcagat tgggcaagga aatgtgaaag agcatcagtt gatcgatgca
    16081 aagacccaat tagcaaatct acatcaagaa gaaactttga agaaaaataa agtattgaag
    16141 aaggcgaaag aacaaaaaac gttgaaaccg ggagacgaag tgttggttac gacttacggc
    16201 caaagaggga cgcttttacg taaaaacggg aatcagtggc aagtagaaat cggtatatta
    16261 aaaatgaatg tgtccgaaga cgagctgacg cctgttgctc ctcaaaaaga gccgacacaa
    16321 cgagttatcc atgctgtacg atctgaatct agtagtcacg tgccgaatca attggacctt
    16381 cgaggaaaac gatacgaaga agcgctaagt gaggtagatc aatatttgga ttctgccatt
    16441 ctagctggtt atcctcaagt gactattgtc cacggaaaag gaacaggcgc acttcgcaag
    16501 ggaattactg attatcttaa aaaccatcgg agcgtcaaaa gctttgagtt tgcaccggca
    16561 aaccaaggcg gaaatggtgc gacaattgtt aaatttaagt aaagcttact aaaggtaagc
    16621 agatggttcg ctatccaagt atagaaatgc tatactagtc atagatttta aaaatggagg
    16681 tctttgatat gtcacaagta attacagata agacatttaa tgaagaaaca gataaaggac
    16741 ttgtattgat tgatttttgg gcaacttggt gtggtccatg tcgtatgcaa gcaccgattt
    16801 tggatcagtt ggaacaagaa tatgatgaag aagaattcag aattgctaaa atggatgtgg
    16861 atgaaaatcc agaaactcct caacaattcg gtatcatgag cattccaaca ttaatgttga
    16921 aaaaagatgg tcaagtagta gaaaaagctg ttggtgttca ttcaaaagaa caactacgtc
    16981 aaatgatcga tcaatattta taaaaactta cagcaaaaat aagctgaggg tgggactgaa
    17041 tccagttccg tcctcggttt ttttgcggtt gagttaaggt tattcaaatt aatatttttt
    17101 gagtataatt acgttgtcag gctggattgt ttttttgaca gacatgctat aataacttta
    17161 attgaatatg aaggggagta ccagatgaac gaacgaatca aaaacaaatt agctttactt
    17221 cctgatcagc ccggctgtta cttgatgaaa gataaaaatg gaacgatcat ttatgtcggc
    17281 aaagccaaaa tattaaaaaa tcgtgtccgc tcatatttta ctggtagcca taatacgaaa
    17341 acggaacggc ttgttagtga aatcgaagac tttgaataca tcgttacaga atcgaatatc
    17401 gaagcattgc tcttagagat caatctgata aagaaaaatg atcctaaata caacattatg
    17461 ttaaaggatg ataaaaccta tcctttcctt aagataacga atgaaaaata tccccgtttg
    17521 gtgattactc gtaaggtact aaaagacaaa gcactgtatt ttggaccata tcccgatgtc
    17581 ggtgcggcga atgagacaaa gaagatcctc gatcgattat ttcctctgag aaaatgcaaa
    17641 cctagtcaga cgaaggagcc ttgtctttac tatcatttgg gacaatgcct gtgtccttat
    17701 tatttcgacg tagatccgaa agtctatacg aaaatcgttg atgaagtgaa aaacttttta
    17761 aacggaggac acgaaaaaat cgagtcagag atccatcaga aaatggaaaa agctgctgaa
    17821 aacatggagt ttgaaaaagc tgcagaatac cgagaccaga tccgtgccat tgagacaatc
    17881 atgactcgcc aaaaaatgac aaatactgat ttactggatc gagatgtatt tggttatgcg
    17941 attgataaag gatggatgtg tgtccaagtg tttttcgtaa gacaaggaaa gctaattgaa
    18001 cgagatgttt caatgtttcc tttctataac gaagcagaag aagatttctt gacttacctc
    18061 ggtcagtttt atcaggaaaa tgagcatttc attcctaaag aagtcttgat tcctgatacg
    18121 atcgacaagc ccagtgtaga agctttgtta gctacgaaag tgctgcaacc aaaacgagga
    18181 gaaaagaaaa aattagttga attggcgagt aagaatgcct cagttgcttt gaatgaacgg
    18241 tttgatctga ttgccagaaa acaggaacgg acgatcggag cagttgaacg tttaggaaac
    18301 gcgatgaata tcccgacccc aatacgtatc gagtcttttg ataactctaa tatcatgggg
    18361 acgaatcctg tggctgcgat ggtcgtattc attgatggaa aaccggcaag aaaagaatat
    18421 cggaaatata aaataaaaac agtcaacgga ccggatgatt atgcatcaat gagagaagtc
    18481 atctatcgca gatattcgcg agtgattcgc gaagggttgc ctttacctga tttgatcttg
    18541 atcgatggag gaaaaggaca agtagatgtg gcaaaagatg tcttagaaaa tcaattagga
    18601 atcgatattc ctattgctgg catggtaaaa aacgataaac ataaaacaaa tgagttgcta
    18661 ttcggtacag atttggctgt agtaccgctt gagcgaaatt caccagagtt tttcttactc
    18721 cagcgaatcc aagatgaagt ccatcgattc gcaatcactt tccatcggca gctacgcagt
    18781 aaaaacagtt ttgcttcccg attagatgaa attgaagggt taggaccaaa acgaaaaaaa
    18841 atgctgctta aagagttcaa atcgttgaaa aatatcacag cagccacgac agaagaatta
    18901 caagaaatcg gactgccgaa aaatgtcgca caaaacgtat ttgataaatt acatcaggaa
    18961 tgaggaaagg gcactttaca aagaaagtaa agtgtcctat cattttatgt acaacaaaaa
    19021 gagcgtttac gttttgttgg taaataataa atcgcttacg tctggtgtct aaggatatat
    19081 gtgatttctt gaagaaggag tgaagaaatg ttagaagtca aggatcttgt taaaactttt
    19141 gggaactaca cagctgtcga tcatgtctct ttccaaatcc ccgatggaaa aatcatgggg
    19201 ctaattggcc aaaacggggc tgggaagaca acgacttttc gtttgatctt ggattttttg
    19261 acacaagacc aaggagaagt gttatggaat ggccatcatc ttggggagaa agattatgat
    19321 gtcatcggtt atcttccgga ggaacgggga ctttatccga aagtaacgat tcaagaccaa
    19381 ctgctttatt ttgcagaact tagagggaaa tcaagaaaag agattgaacc aaaaatcgac
    19441 ttttggatgg aaaaatttca ggtaaaaggg aaaaagacgg ataaagtaaa atctttgtct
    19501 aaaggaaatc agcaaaaagt ccagctgatc gccacgttaa tccatgaacc taaattgatc
    19561 attttggatg agccattcag cgggttagat ccggtaaatg ctgaattgct aaaagatgga
    19621 atattggaat tgaaaaaaca tggttcatgt gtcatttttt ctagccacaa tatggataat
    19681 gtagaaaaaa tctgcgatca tttgatcatg ttgcgaaacg gaaaaatggt tttgaatgga
    19741 aaagtacatg agattcgtga atcatttggc cgtacgaagt tattcttgga atctggttta
    19801 agccaacagg aagtagaaga aatcgaaggc gtgaaaaaag tgatccttca tgaagacaat
    19861 acgttagaga ttaccttaga agatcctgaa gctgggaaag aaatctttac tcgtgcgact
    19921 cagttcggct acattcctat gtttaaccag caaccgccaa ctttggaaga gattttcaaa
    19981 ttgaaagcag gtgaaatcga tgcgtaagtt ttggattatt accaaagatg tctatttaaa
    20041 aaatgttaag tcgatttctt tcttgatcat gatattagtc ccttttatca tgctgggtat
    20101 catttatgta gcaggaaact ttgctcaaca aaatagtgat gtcaataaaa tcggcgtatt
    20161 ggctgataat gagcaaatca gtcagcaaat gagccaagtc aaaacagatg attttgagtt
    20221 caaagcagtt gattctgaag aaaaagcaca aaaagagctt tcggaagaaa aaatcgatgc
    20281 gtatttagta gtctcaactg agaatgataa gataaatggg atgctttata gcgaaaattc
    20341 attaggacaa agtacacaac tactgataca acaacaactg actggcttgc aatcgatgct
    20401 tcgagcgagt caattaggca tttcaccaga agaagtagct agcttgagcc aacaagcaag
    20461 tttgactcga caaaaagtca attttgattc aaaaggaaaa atgacagtcg gagaagataa
    20521 ctcgacagtc caatacgtcg taagttatgt agcaacgatt gtcttgttca ttattatttt
    20581 gacgtatgcg cagatcattg cacaagagat cgcttctgaa aaaggcacgc ggatcatgga
    20641 agtgatcctg tccagtacga ctgcacaaaa gcatttttac ggaaaattaa caggtgtttt
    20701 acttgttgca ttaacgcaaa tggcattata cggtattatt tttggtatag gatacagtca
    20761 attcaaagat atggaaatgg tcaaaaatat attagacggt atctcattgg ataacttgat
    20821 tggaccattc ttgtggtatt ctcttctatt catgatcttt ggcattttga ttttttctgt
    20881 tttagcagct ttatgtggct ctttggtcaa caaagcagaa gatacagcaa aagcaatttt
    20941 gccagtgact tatctatctc taggcggata catgcttgga ttgatactag gagcttcaga
    21001 tccaaacaat atcgttattc ggatcacttc gtatattcca ttcttatctt catatattat
    21061 gccgattcgc ttagcaaatg agacagtcgg tatgggtgga gcattgattt ccttgttggt
    21121 acttgtagcc gtaacattct tattgatgat cttgtctgca aacatgtaca aatcgaatgt
    21181 actcgtttat agcgaaggcg gattatggag ttcattgaaa caatcgattt caattatgag
    21241 gaatgaacga aaaaaagcat aaaacaatcc taaaatacag aaggaagctg gacatctatt
    21301 gttcccagct tctttttgta tagacctatt ttatttattt tactatattg gatatatatt
    21361 cattgaaaat agtgtataac aactttataa tattgagtat accaattttt ggaggcgttt
    21421 taatggaccg ttatttagat ttactttcag aaaaattccc ctcaacggag gatgtcatca
    21481 cggaaatcat caatctcgaa gcaattttgc agcttccaaa aggaacagag ttatttttga
    21541 gtgatataca tggcgaattt cctgcttttg atcatattct gcgtatcggt tcaggaaatc
    21601 ttaaagaaaa gatcaaagac cttttttctg aacaaatgac ggaaacggat atcagccaat
    21661 tcactatttt tacggcttat ccagaatatg cattaacgac tgattggtac aaagaacaag
    21721 ataaatcgca gctgatccat catttgatcg atcttttacg gtttacgaca gtcaaatata
    21781 cccggtcaaa agttcgaaaa ggattgccga aagaatatag ctatatcatt gaggaactct
    21841 tgtatatcga tgaccgtatc aatggaaaaa aagactatgt aaaaaaaatc attgaacaac
    21901 ttgttttgat gaaggaagaa gaaaaatttt taacgaaact tgcacagacg atccaaaaat
    21961 ctgtcatcga tcatttgcat atcgttggag atatttttga ccgaggaact caagcagcca
    22021 aagtgatgga tcgaatcatg gatttttctt ctgtagatat ccaatgggga aatcatgata
    22081 ttttgtggat tggtgcgtat tgcggctctg aggcatgttt actgacactt ttacggattg
    22141 cagcacgcta taattattta tttgaattag agaaagaata tgggttgaat ttacgtccat
    22201 tgttttcttt tgctcatcaa acttatcaga agaatccagt atttgcgcct aaaaacagta
    22261 aaaatctatc cgaaagagag caagaagaat tagaaaaaat ccatcaggca ctttctatcc
    22321 ttcaattcaa atcagaacat cagttattgg atcgtcgacc tgaatttaaa atggacgatc
    22381 gtaaattgct ggaaaaaatc gactatgaag catcaacgat tgatttagaa ggtcagctct
    22441 atgagttgaa aggaacttgt tttcaaacga tccagccaga tgatccaaaa aaattcttgg
    22501 aagaggaaca aaaagtgatt gatagtttga tgtattcatt ccagcactct ttgagaatgc
    22561 aaaaacatat gacgtttttg atcgaaaaag ggggaatgta tctcacgaac aatcagcatg
    22621 tgctgtttca tggctgtata cctgtagacg agaagggaca gctcttagca tttgaattag
    22681 accaatctta tcgcggaaaa gaactgctgg gcttttttga aaaacagata actgaaagcg
    22741 caaaagatct gactgcaaaa gaagatttag caaccgattt gatttggtat gcgtggagtg
    22801 ggccattttc gcctttattc ggcaagagta aaatggcgac ttttgaacgt tattttctca
    22861 cagagcctca tacgcacgtc gagaaaagca atccttatta tcacttgcga gatgaagagt
    22921 ggttcagtga aaaaatttta gcagaattcg acacaaaaga agaagggtca gcaatcatta
    22981 atgggcacac gccagtaaaa gtaaaaaaag gggagtcacc gatcaaagca aatggaaaag
    23041 tatttgtcat tgacggaggt ttatccaaag cttatcaaaa aacgacagga attgccggtt
    23101 attcactatt atgcaattct tatggtttcc aaatcgtgac acattatccg tttttgccta
    23161 ttgaacaaca atttgcaaaa aaatccgacc aaacaaatgt gaaaaaagta atcgaacagc
    23221 aactaccacg caaactcaat cgtgatacaa caaaaggtat ggaactgcag cagcagatta
    23281 cccagctcaa aaggctgttg gactatcgaa aggacgattg agaagaattc cagtgaacat
    23341 tgttccatag actggagact gagacaaaag tcgtgtcgca gtctcttttt ccggataaac
    23401 ggtgttcttc tgccaactcc tcggtcacaa gtcacactat tcaacaaaca tgaaaagctg
    23461 ttttttgaaa ttgctccttg tgactcagag ttgaacggca ggctcacgac ctcttggtat
    23521 aaacggtgtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtgaaaa
    23581 gccattttca caaaattttt cttaatactc gaaactaaac agctttttca caaccccctc
    23641 agaaagtcta ttaaaattca ttcacaaaga aatcgaataa gcgctgttca gatggatgta
    23701 cacggtgggt aagttccgga tgccattgaa caccgaggat tttatgcata tcatctttgc
    23761 tttgaaccgc ttcaacgagt ccatcgttag aaaaagcgat ggcttttaat aaaggtgaaa
    23821 gatctttgac tgcctgatga tggtaagaat tcacaaaata tggatcgggg agaaggttgc
    23881 ttaacaaact gtctgaaaca atcttgactt cgtgagtcgt aaattgcggg gcagtgggct
    23941 gttgttcatg ttttactgac cactttggat ataatgaaag atcttgataa agtgtacctt
    24001 ccaaaacgac attcaatagt tggagtcccc ggcagactgc aaaaattggt tttctttgtt
    24061 tcaatgcttc caagatcagt gcctgttcaa attggtctcg ttgaatattt gtttccgtta
    24121 gctttggatg aggatcttcc atgtaaagtt gtggactgac atcttgacca cctgcaagaa
    24181 taagtttgtc gatttgtcca atcagttgag gagctgaatc tggagacatg actggcagaa
    24241 taagaggcaa tccttgagca tctaaaactg catccacgaa tccttgcggt gtatagctca
    24301 cttgatttcc ttggaaagta tctgttgctc gaatcagttg atttccggca atgccgatga
    24361 ttggtttcat ttgtattccc cctaaagtag acttattgta acaaggattt aaaaaaatta
    24421 aactatgtaa gacttgcccc tatacttatc tgttcttgct gtgttactat ctgtaaagag
    24481 aaatttcgtg tgaaattcat gacgatagtt gaaaatattg cttaatttgt tataataaaa
    24541 agtaagcaga aataaaaagg ttgggcgtaa gcttcaagga tctagttctt caaggggtga
    24601 gaaggacatt ttattgaagg ggcctgccta tactaagtta tctttagagg tacatacttt
    24661 caatgaaaaa agaaagcatg tacctctttt ttaaatcgaa aggaagtgaa gcaagtgtta
    24721 gaagctttgg aacaaatccg aaaagcagaa gaagaaaatg aaaagcgtgc tcaaacactg
    24781 cggcagcagc tgaagatcta tgcaacagaa aaagagcagg aattggaaac gatccaaaca
    24841 aactatcgac aacaactaaa acagttggtg gaagaaaaag aacaatttga aatacaagaa
    24901 ttagaaaaag aaaaaatgaa attgaaagca gaagcagaca aggtgcaagc aactttgaaa
    24961 gatcaatatc aaaagcatca gagtcaagcg atcggtgcga tcattgaaag ggtgaaagaa
    25021 acttatggcc gtcactaaga tggaaaaagt gaccctcatt tcagataaaa gaaatcagga
    25081 gaggatttta caagcagtac aaggaatcca aaacgttgaa atccgggatc tgtatcaaaa
    25141 tagaacaaac aaccagtggg tggagaagta ttttccagat accacgatta ttgataaaga
    25201 agcaaaatta agcgctttag gtaatcggtt gaaagacatc caagaagcta tccaattcat
    25261 acaacaccac ggcgatagcc gtcaaaagaa actccatttg aaacgtcaag aactttcctt
    25321 acaagatttg gaagccaatt attccgaaga aaatttcata aataaattga aagaagtcct
    25381 tgatttaaaa gaaaagtggg aacaactaac tgaagaacgt gatcgtttag aagaagagga
    25441 agaatggctt cttcattggc aacagctgga tattgctcca agtatgtatg caagtaagac
    25501 gaccattttt gagatgggga ctgtgagtgc agcaaatttt gaaagtttca aggaagaact
    25561 gagtaagctt gatgacgttt atatggaaga aatagattat acgccaaaac aagtttatct
    25621 ttcgtatgtt gctttaaaaa aatcagttgc tgttatagaa gaaattgctg ggaaatacgg
    25681 gttcaataaa gaaacgtatc cttatgaaca aaatcctaaa gaaaaactgc aagagaccaa
    25741 gcagcaatta tccattgttc acgagcagca aaagaagata acgacagcgt taggtcagtg
    25801 cagtggctat atccaagaat ttgaatgggt agaagaagtc acacttgccg ttgcagaacg
    25861 agaaaaaata aaagaacggt ttatccatgc gacttatctg atcgttttgc aaggttgggt
    25921 agatgcagaa gaaaaacaga atttgctgca tgtgttaaac gaaaccgtat cagaagaaga
    25981 tatatacgtc agtttcgaaa caccaaactc agaagagatt cagcaggaag tccctactaa
    26041 attgaaaaac catccgcttg tcgaaccttt tgaattgctg actgaaatgt acagtctgcc
    26101 aaaatatgaa gaagtagatc caacaccttg gatgacacca ttttatcttg tcttcttcgg
    26161 gatgatggtc gcagatgttg gttatggttt gctgatgctc attgggacaa tactagctca
    26221 aaaactactt gttctaccac gcgggatgaa acgtttcgta aaattctttg agattctctc
    26281 gataccatcg atcatctggg gattgatcta cagttcattt ttcggacagt cattaccaaa
    26341 agaactgttt ggcatccgct tgcctttccc aatcctatct acgacggatg acgtcaatac
    26401 gattttgatt ttatccgtga ttttcggtct gatacagatt ttggttggat tatttgtggc
    26461 agcaaaggaa aatatcagga gaaaagatta cttgagtgct gtcagtgatg gatttgcctg
    26521 gcaagggatc ctaattggga tcgttattgc gttggttggt gccatgttga taaaaaatac
    26581 agcatttgtt taccttggcg ctgggctatc gatcattgct gccttatgta tcttgatcgt
    26641 tccgattatc caaacgccgt ctaaagtcaa aggtgctgcc aaaggtgcgt ataatcttta
    26701 cggactgacc ggctatatcg gtgatttagt cagttataca cgtttgatgg cattgggtat
    26761 ttcaggcgga agtattggag cggcattcaa tatgctagtt gctttcatgc cgccagctgc
    26821 tcgattcagt gtagggatcc ttttgatcat cgctttacac gcactgaata tgtttttgac
    26881 actgctaagt gcctatgtcc atggcgcacg attgcagtat gtcgaatttt ttgggaagtt
    26941 ttatacagga ggcggacgtg cctttgatcc gctgaaaacg gcggaaaaat acgtcaacat
    27001 caatcacaag aaaaaaaaca ataaataatt ggaggatttt tatataatga tggattactt
    27061 aattagtcaa aatggtggaa tggtatttgc ggtattagcg atggcaacag cgacgatttt
    27121 ttcagggatc ggttcagcta aaggtgttgg aatgacaggt gaggcagcag cagcattgac
    27181 aacaagtcaa cccgaaaaat tcgggcaggc tctgattctg caattgcttc caggcacgca
    27241 aggtttgtat ggattcgtta ttgccttttt gatttttatc aacttaggaa atgacatgtc
    27301 agttgtacaa ggactgaact ttctaggtgc ttctctgccg attgctttta caggcttgtt
    27361 ttcaggtatt gcccaaggaa aagtcgcagc ggcaggtatt caaattttag cgaaaaaacc
    27421 tgaacatgct acaaaaggaa tcatttttgc tgcgatggtt gaaacatacg cgattttagg
    27481 tttcgttatt tccttcctat tagtgttgaa tgcctaagca taaaggagga aaagcagatg
    27541 aacgccattg aaaaaatcat ctctcagatg aacgaagcag cagagcagga aagagcggcg
    27601 ttagaacaag aagagcgaat gaagatcgat caaaactttg aacaaaaacg tacgcaagtt
    27661 gaaacagaac atcaaaaaca aaaagaaaaa caaatcgaat tactcgaaaa aaaataccgt
    27721 cagctaagga atcgccagca agtagaagta cgacaagaaa atttgaatgc gaagcaggaa
    27781 tttttaagac gattgtttgc agatgcggta actgaaatgg aaaattggga tgaatctgaa
    27841 caaatccagt ttatcaaaaa tgcattgtat tcattacctt tgacaggaaa agtagcattc
    27901 attgctggag aaaaatcagc agcctatctt tctcagacgt tgttggatga atggaacaat
    27961 gaacttccct ttatgatggt tttaagtgat gaaactgttg ctgatcaagc gggttttctg
    28021 ataaacgatc aaggagttca gtataatttt cttttcagca gccttgtaca agatatccaa
    28081 ggaacgatga gttttgagat tgccaatcaa ttattcgaat aaggagggat cagtgtatgg
    28141 aataccacga actaaatccc ttgattcgcg gaagagagct tgaacttttg tccaatgaga
    28201 catttgaacg gatgattcaa acaaattctg tcgaagcact tggtgaaata ttgaaatcca
    28261 cgatttacag tccatatatt tatgacggat atgaatatga cttcgaacag aatcttttaa
    28321 aggagcagag ccgtctattt cgctggttaa aggaatcagc accggagcct gaaatcgttt
    28381 ggatctatac gatgcgttat actttccata atctgaaggt tttgacaaaa gctgagatga
    28441 caaatcaaaa tctggaccat ttgtatatcg acgatggatt ttattcatta gaaaccttga
    28501 aggatgccat tcatacgcaa gtttcaaatg aacttcctga aagcattatg gacagtatac
    28561 gagaagtacg tgattatttt gaagagtcta ccattcttca gggaattgac gtgatttatg
    28621 atcgacagtt tttgacagag cagcgacggc ttgccgataa gctaggatat caagaattgc
    28681 tgacagaagt cattgctttt attgacttga ccaatatcac aacgatggct cgaggaatat
    28741 tgcagaaaag aacatatggg ttcatgacga cggtactttc cagctcggga agtatcgaaa
    28801 aagaagtatt tttgaacttt gtagataaag atatggaaga ttacacgaat tttctattag
    28861 agacagatta tgctgatttt ctgcgccctg tcatccgtga gggaaatatt gatctcgtaa
    28921 agcttgaaca gttgaaagat gattatctaa gttcattgta tcaagaagca caaacccagg
    28981 ctttcggacc actgccacta ctagcctttt tgaacgcaaa agaggtagaa agcaaaaacc
    29041 ttcgtttact ggttatcggc aaaagaagcc atttcgaatc agaaacaatc agaaagcggg
    29101 tgagacaagt ctatgacgca taagatcggt gtagttggcg acaaagattc tgttttgcca
    29161 ttcaaattgt ttggctttga tgttcgttat ggtacaacca agcaaaccgt tcgtcaggca
    29221 attgaagaaa tggcaaagaa tgagtatggc gtgatttatg tcacagagca atgtgcagca
    29281 ttgagcccag aaacgatcga acgttacaag gaacaaatga tacctgctat cgtattgatt
    29341 cccaatcatc aaggatcatt agggataggg ctggaagaaa ttcaaaaaaa cgtagaaaaa
    29401 gcagtaggtc aaaatatctt atagtatgaa aaggagatag aaattttgca aattggaaaa
    29461 atcataaaag tctccggacc tcttgtaatg gctgagaaca tgtctgatgc cagtatccaa
    29521 gacatgtgtc tagtgggaga tctaggagtt atcggagaaa ttatcgagat gcgtggcgat
    29581 gtggcgtcta ttcaagtata tgaagagact tctggaattg gtccaggcga accggttcgc
    29641 tctactggtg aagctttatc tgttgaatta ggaccaggga tcatttcaca aatgtttgac
    29701 ggaatccaac ggccattaga tacctttatg gaaatcacac aaagtaattt cttagggcgc
    29761 ggagttcaat tgcccgcatt ggaccatgag aaaaaatggt ggttcgaacc aacagtagaa
    29821 gccggagaaa cggtgagtgc tggagatgtt atcgggatcg tagaagaaac aaaagttata
    29881 aaacataaaa tcatggtgcc aaatgggata aaaggaacga tcaaaacaat cgaaaaaggt
    29941 tcattcacta ttgatgaaac agtatgtgtc attgaaaccg aaaatggtga caaaaatttg
    30001 acgatgcttc aaaaatggcc agtaagacgt agtcggccaa tcaaagaaaa attaaacccg
    30061 gatgcaccca tgatcactgg acagcgagtg attgatacat tcttcccagt gacaaaagga
    30121 ggagcagcag ctgtacctgg tccttttggt gcagggaaaa cagtcgttca gcatcaaatt
    30181 gcaaaatggg ccgatgtgga catggttgtc tatgtgggat gtggcgagcg tggaaatgag
    30241 atgacggatg ttttaaatga attccctgaa ttgattgacc ctaatacagg agaatcgttg
    30301 atggaacgta cggtattgat tgctaataca tcaaacatgc cagtagcagc tcgagaagct
    30361 tctatctata cgggaatcac aattgcggaa tatttccgtg acatgggtta tgacgttgct
    30421 atcatggcag actccacttc acgatgggca gaagcacttc gtgagatgag cggacgtttg
    30481 gaagaaatgc ctggtgatga aggttatcca gcttatcttg gttcacggct tgcggaatac
    30541 tatgaacgat ctggaagagt cattgcatta ggatcagaag gtcgcgaagg aagtataacc
    30601 gcaatcagtg ctgtatcccc gtctggaggg gatatttcgg aaccagtcac acaaaataca
    30661 ttgcgggtcg taaaagtatt ctggggtctt gattccagtt tagcccaaaa aagacatttt
    30721 ccttcgatcg attggataca aagctattct ctttattcaa cagaagtagg gaagtatatg
    30781 gatcatatcc ttcaagctga ctgggcatcc atggtcaccg agggcatgcg tattttgcag
    30841 gaagaacagc agctgaatga aatcgtgcgt ttggtaggga ttgattccct ttcagataat
    30901 gaccgtctga cattagaagt ggcaaaatcc attcgtgaag attatttgca gcaaaatgct
    30961 tttgatgatg tcgatacatt cacttcaaga gagaaacaat tcaaaatgtt gaagatgatc
    31021 ttgacctttg gtgaagaagg acgccgtgcg ttgtcgttag gtgcttattt aagtgagatc
    31081 atggacggta ccgtatcgat tcgtgaaagg atcggacgaa gcaaatatat cccggaaaca
    31141 gaattagaaa aactagatca aattattggt gaaatcaagc aaacgatgca aacgatcgtt
    31201 tcagaaggag gcatgagcaa tgattaaaga atatcgtacg atcggtgaag tcgtcggtcc
    31261 attgatggcg gttgaaaaag ttgctggtgt caaatatgaa gaattaatcg aagtccgtat
    31321 gcaaaatggc gagattcgtc gtggacaagt attggaagtc caagaagata aagcaatggt
    31381 ccaaatattc gaaggaacaa gtggtatcaa tttacgtgac tcttctgtac gatttttagg
    31441 ccatccttta gaactaggtg tatcggaaga catgatcggt cgagtattcg atggtttggg
    31501 acgaccgaaa gataacggac cagagatcct gcctgaaaag catttggata ttaacggaga
    31561 agtaatcaat ccagtagctc gggattatcc agatgagttt atccaaacag gtatctctgc
    31621 aatcgatcat ttgaatacat tagttcgtgg gcaaaaatta ccagtatttt ctggctctgg
    31681 tcttcctcat aaagaattag ctgctcagat cgcgcgacaa gcaacggtac tcgattcatc
    31741 agatgatttc gccgtagtct ttgctgctat tggaatcact tttgaagaag ctgaattttt
    31801 catggaagat tttcgtcaaa cgggcgcaat cgaccgttct gtcatgttta tgaatttagc
    31861 aaacgaccct gcaatcgaac gtatcgctac tcctcgtatg gctttgactg ctgcagaata
    31921 tcttgcttat gaaaagggaa tgcatgtttt ggttatcatg acagacatga ccaactatgc
    31981 agaggcattg cgagagattt ctgcagcacg gcgagaagtt ccaggaagaa gaggatatcc
    32041 tgggtatctt tacacgaact tagctacttt attcgaacga gcaggaagaa tccgcggact
    32101 aaaaggatcg gttactcaaa ttccgattct aacaatgcca gaagacgata aaactcatcc
    32161 aatccctgac ttgactggtt atattacaga aggacagatc atcttgacta gagagcttta
    32221 caagagtggg attcagccac caattgatgt actcccgtct ctttcgcggt taaaagataa
    32281 gggaactgga cccggaaaga caagagaaga ccatgcagct acgatgaatc agctttttgc
    32341 agcctatgca caaggaaaac aggcaaaaga attagccgta gttttaggtg aatctgcttt
    32401 atctgatgta gacaagatct atgcgaagtt tgctgagcgg tttgaaaaag aatatgtcaa
    32461 tcaaggattc tacacgaacc gttcgattac tgaaacactt gatctagggt gggaactgct
    32521 atcgatgttg ccaagaaccg aattaaaacg aatcaaagac gacatgctgg acaaatatct
    32581 gccagaaggg aagtgagttc tgatggcacg attgaatgtg aatccgaccc gcatggaatt
    32641 gactcgattg aaaaaacagt tgacaactgc cacaagaggg cataaattat taaaagataa
    32701 gcaagatgaa ctgatgcgtc aattcatcct gttgattcga aagaacaacc agctgcgtca
    32761 agaaatggaa gagtctatga cagaagcaat gtctgatttt gtattggcaa atgcttcgat
    32821 cacggaacct ttcatcgaag aattatttgt tttgccggcg gaaaacgttg atttgtctat
    32881 cgtagacaaa aatatcatga gtgtaaaagt acctgtgatg aattttgaat atgatgaaca
    32941 gctgacagac acacctttgg aatacgggta tttgaattcc agtgccgaac tggatcggtc
    33001 aatcgatcgg tttactaccc tgcttccaaa acttttggaa ctgacagaaa tcgaaaaaac
    33061 ttgtcaactg atggcgagtg aaatcgaaaa gacacgtcgg cgagtcaatg cattagaata
    33121 tatgacgatc cctcaattag aagaaacgat ctattatatt cgtatgaagc tggaagaaaa
    33181 cgagcgcgca gaagtaacaa ggttgatcaa agtaaaaaat atgggtacca ctgactaagt
    33241 ggtatctttt tttaaaagag gaaaacgatg attaaacaaa gcaaacaaat aaagaaacgt
    33301 ttgccggctg ttcagcttct cgcattagga ttttttctcc tgattttagt tggcggcggc
    33361 ctacttaccc taccattttt tagtaatagt gggcatggga caaattttat cgatgcgctt
    33421 ttcactgcaa cttctgctgt ctgtgtaacg ggattgacaa cattgaatac agcagagcat
    33481 tggaacagtg ctggtcaatt tttgatcatg cttttgattg agatcggcgg tcttggtttt
    33541 atgatggttc cgattctatg ctttgcattg ataaagaaga aagtcagtct cagcacacgt
    33601 attatattaa aagaagcgct gaatctagaa gaagtatcag gtgtgatgaa gctcatgctt
    33661 tacatcctaa aattggcctt tgtgatccaa ttgattggta cggttgcttt atcttttgta
    33721 tttgtgcctg aatttggctg gttgaaaggt atctggtaca gtttgttcca tgcaatctct
    33781 agtttttgta atgcagggtt tgatttgtta ggagacagtt tagccaatca ccagcaaaat
    33841 gtttatttga tcatggtggt atctgctttg atcatttctg gtgggttagg cttcatcgta
    33901 tggcgtgatt tactggaata tcatcagaaa aagaagatga cgattcattc aaaaatcgca
    33961 ttaaccgtta caggtaccct tttattaggc ggattcgttg tgttcttttt cacagagcgc
    34021 aatggggcaa cgctagtgga agggaatatg tttcaacgat tggcaaacac cttttttatg
    34081 agtgtgacac ctagaacggc tggatattat tcagttgatt acctccatat gagccatgca
    34141 ggtctgattt taacgatgtt tttgatgtac atcggcggaa catctgggtc gacggccggc
    34201 ggattgaaaa caactacgtt aggtgtgttg ctgatccaga tgcgttcgat gttgaaagga
    34261 cgtacgagag cggaagcatt tggccgtacc atccgacaag gcgcagtgtt gcgggcactt
    34321 actttatttt ttgttacgtt gacgttgtgt gtagtcgcca tcatgatttt atcggtgact
    34381 gaaacgatac ctaaaacttc tggcatcgaa tatattgctt ttgaggtctt ctctgcgttt
    34441 ggtacagtag gtcttacgat gggattgacg ccagacttga ctgcaatagg gaaattgatc
    34501 attatagcgc ttatgtacat tggacgagtt ggtgtattga ctgtggtctt ctctctgatg
    34561 acaaaagcac aaagaacaca atcaaaatac aaatatccag aagaaagtgt catgattgga
    34621 taatttcatc ttctgacaga aacctagtga tttagtaaaa taagaaaata aaataatttt
    34681 tcttgcttct tggatacttt aagtgcaaaa tgttcgttta ttttttgagg cactacccgt
    34741 tgttgaacct cgggtagtgc ctctttttta ttgaaaggaa tcaataagat ttgattcctt
    34801 tatttatcaa taggttataa ttcatatttt tttatttttt cttttacgat acttagtcca
    34861 gaagctaaaa tttcaaggtt attagaggat agggaaattc gaacgaatgc atctggttgc
    34921 gcacgtgtag taaagcgtct ggaatgataa agtcggatac cgttagcaag aaagtcattc
    34981 tcaattatct tagggtcaat ctcaggatca actggaagaa ttcgatagta agggacacga
    35041 ttcgttggtt tttctacttt gaaaagagaa tcaaaaagct gattggctct ttttgtaaga
    35101 cttaatttag tttctaagat cctatttgct tcatttgaat ggaggatttg agtgatgact
    35161 tccacatcta atccagaagt tttcacattt atattaaaaa ttgcttgttc tatcttgctt
    35221 tggacatgta ctggaactac aagataagca actcgcaatc cagaacaaat aaattttgtc
    35281 attccagcta agtagattgt ttggttaggt aataaatttt ggaaaggagg aatgatcgta
    35341 tgttgatagt aagttgttaa aaatgaatgg atatcatctt caataaccca tagaccttct
    35401 ttttcaatca cttcggctaa ttgctctcgt cttttgtgag agatttgaaa ccctatagga
    35461 ttattacaag aaggcataag aaagacacca tgaatcttct tttttctaca ttcctgaatc
    35521 aatatatcag gtcgcattcc ttgctcgtca aaatcaattg gaacgatctc taaatgatat
    35581 aactgagcca attcaatgaa attagcgtat gtatatcggt ctgttgctat tctatcacct
    35641 ggagagaaaa gtgcagaaag tgtgatagcc aatccatttt gaacaccgga aacaatagat
    35701 agagattcta aggacggaat gactccttga gtttttaacc aatttgctgc agtagtcaat
    35761 tgaaaatttg tgcctttggg atcttggtaa ttaagcaaac caacaagatt tgggttatta
    35821 ctagttgatt gaataaacgg gacaacgaat ttattacatt cttcaaaaga actaaccaga
    35881 ccaaaatcaa tgatatgttc ggttacttca ttggtagaga tggtgatgga ctcaaagaca
    35941 ttgggagaaa taaatgtgcc acttccaata ttcgtataca gcaaaccttt ctcaattcca
    36001 tatttataag ccttgccaac ggtagtaaaa tttaaatcta aataatcagc tagctctctt
    36061 tgggagggta actgagtgtt tttctgtaat ttattcttta aaatatcttg ttctaattgt
    36121 tgaatcaacg atcgataata aggacgcttc aatttttgtt tgtctggtcg ccaagttaac
    36181 gggtaattgt cataagaatt aataggcatt ttctccactc cttaaaattg tataccatac
    36241 aattttacca ttgattgtat tgattttaga agttaatctt ttgtgaggag ggaattgtct
    36301 atgaaaatta ttaattttga ggaagtagta gcttctttta gttttgaaga agcgattcaa
    36361 gtaatgaaaa aatgtttttt tgattatgaa agtggtaaaa tcagccaaaa tcctcgattg
    36421 gtggaaattt tacctgacgg aaaaggcaaa aatatgtttg cgatgatgcc tgcttatttg
    36481 ggggagaaca gatattttgg cacaaaagtc attaccgctt ttccggataa tcatcagtat
    36541 catttacctt ctcatttagg agagattttc ttgtttgatg ctcaaaacgg actacccaaa
    36601 gcattgataa acgcaaatgc agtcacctgg attcgaacag ctgctgtatc tgcgctggca
    36661 acagattact tagcaaatcc gcatgcagaa acacttgctt taattggagc tggtcaacaa
    36721 gcattgtcgc atttgactgc gatttctacc attcgtccca tcactacagt gtttgtttac
    36781 gatattttag aagaaagacg aaatactttt atcgctaaag ctaaaaaaca gtatcctaaa
    36841 ataacgttta taaatgcaat atcagtagaa gatgcagtac gtccagcgga aatcatttgt
    36901 acgttgacct ctagtaaaga ggcatttctt caaaaagagt gggtaaggga agacgcacat
    36961 atcaatgctg tgggcacatt tactcctgat acaagagaga taagtacatc gttgatggaa
    37021 acttctcaaa tctatgtaga tgattactca gctgccttaa cagaaagcgg ggacctgctt
    37081 atagccatgg cagaaggaga tttagaggaa tcttgtattg ttggtacatt aggcgaatta
    37141 gtttctgaga aaaaaacatt ttataaagga gaatcgaggc cgacgatttt cgacgcagtt
    37201 ggtctagcta ttgaagatct ttgttgtgca gaatatattt ataacaaatt agagaaaggg
    37261 gctttaaaat gaacttagat tattacgtag ttgatgcatt tgcagatgag gtgttcaaag
    37321 gaaatccagc agcggtttat gtgctagaag aatggctgcc agaaggtacg atgcaaaaaa
    37381 ttgccattga aaacaattta tctgaaacag catttacagt gaagaaaaac caagaatttg
    37441 agcttagatg gtttacgcca gatcgagaaa tcgatctttg tggtcacgcg acattagcaa
    37501 cagcatttgt tttatttaac tattacaaaa tacctgatga aacgattaaa ttttctactc
    37561 aaagcggtaa tctatttgtg acaagaatta aagattatta ttacatggat tttcctagta
    37621 ttatgccgaa aaaagtgccg atattgtctg aatatgaaga agcgattggg gctaagatta
    37681 aagaagccta cttagcacgt gatttatttt tcgtattaga agatgaaaaa acggtggcta
    37741 aattgcagcc agattttaca gctatcaaaa attttgaatt aggaatagga gtcatcgtga
    37801 cagcagaaag tgtgcaaaaa gactttgttt ctagaacctt ctttccaaaa ttaacaatca
    37861 atgaagatcc agtatgtgga tcagcacatt ctaatcttat tccttattgg gcagaaagaa
    37921 tgaataaaac aaaattgtca gcttatcaaa tgtcatcaag gggcggggat ctagaatgtg
    37981 aattaaaaga agatcgtgtg ataataggag gaaaagcagt tttgttttct aaaggtacct
    38041 cgtttatttg atttctttca aatgaattaa aaataaattg gtggagagtg gcaaccttat
    38101 agctacaatg gttgttaaaa aaagacgcaa actttttcaa tttaatgaaa agtttgcgtc
    38161 tcattttaat tattggtgtt tgttttttat tcaatcaaga gtaaaatgcc ccatactaac
    38221 tatcctcgga tgacttcgat tttataacca tcagggtcaa tgacaaagta gtaagaaggc
    38281 gcagtgccag gtaatccttt taagtcagta atctcaagac cagcagcttt atgttgctcg
    38341 tgtaattttt ctagatcatc agctgctata gcgatatgac catagccgtc tcctagatca
    38401 tacgcaccat gatcatagtt gtaagtcaac tctaattcat agtcatcccc aggaagtgtc
    38461 aaataaacaa gtgtaaattt gttttctgga aaatcacggc ggcggctttc ttcaaaacca
    38521 aatgcctttt gataaaattc gattgatgct tcaagatctt tcactcgaac acatgtgtga
    38581 gccattttca tagattcatc tctccttttc cttttactca atcataacaa aaagaagtaa
    38641 ggaaatagtt gatttgtgct tgttcatgag aaatttctca tgtaaaatgg atagaaaata
    38701 aaactgttaa ggtggaaact attcatggat aaaccaattt ttggtgaaaa aaagcaattt
    38761 gctgattatc aaacccgtta tgcagcatat attgtcatag aaagagatca gcagattgca
    38821 gtaatcgagg ctccaaatgg tgcttttttt cttcctggcg gggaaattga aggagaagag
    38881 acgaaagaag aagcgattgt ccgtgagctg atagaagaaa tgggaattgt ggcagaaatt
    38941 tcttcttatc tgggagaagc tgatgagtat ttttactcga attatcgtgc aacttattat
    39001 tataatccag gatatttctt tgttgctgat tcttggaagc gtataggaga accaactgaa
    39061 aagaccaata aaatttggtg ggtgagccct caagaagcgc ttgtgaaatt gaaacgtggt
    39121 agccaccgat gggcagtcga gagatggatc gaaaaaaata aaaactgaaa gaaagcgagt
    39181 agatcagctt tctctcagtt tttttattta ttacagtaca tattttttga ttgcttcagc
    39241 tacaccgtgc tcgtcgtttg atgaagtgat gacatttgct gcttctttga caagagaaac
    39301 ggcatttccc attgctactc ctagaccagc atattcaatc atggataagt cgttctcgtt
    39361 atctccgata gccatgattt catcttgatc aataccaagg tgctgtgcga gattcgcaac
    39421 tgccgcacct ttacttgctt ctttatttag tacttcgaag taatagggcg cacttttgac
    39481 cgttgtgtat ttatcacgga aagtttgcgg taaacgcgca attgctgcat ctaaaatttc
    39541 tggttcgtcg atcatcatca ttttgacgat gttcatgtct ggtgtcattt cttcaggtgt
    39601 tcgatatttt agcggcatct tgactaaact tgcttcgtgg atcgtataag cgctgatatc
    39661 tcgattaggc gtgtagatcg ctttgtcatc gatcgaatgg agatgactgc cgacacggcg
    39721 tgccattact tcgatctcta ggaaatcttc atgtgtcagt ccgtgacggg cgatgatttt
    39781 acctgatttc gtttgttgta cgagtgcccc gttataagta ataacgtaat cattatcttg
    39841 aaaaaggttc aactcgttta actgttcctg gacacctggt aagggacggc cagtgcataa
    39901 aacgatcgaa acaccttttg caacagcagc ggcaatcgct tcttttactt cttttgttac
    39961 ttctcttttc tcatttaata aagtaccatc gatgtcgata gcgactagtt tgatagacat
    40021 aatttcctcc aatatatttt aatttatttc aatcaatgcg ccattacgga tatggctggc
    40081 aaattcttga taagtttcgt caaataaatc ataatgatca cgcaaggacg gatcaaccat
    40141 ttcttttgga aagaaaaatc gctcatctcc ttgttcttgt cccgctaatg cagcaacaag
    40201 ctgactaacc tgtgataatt ctatcaaagt tccgtcattt cgcaaaatct cgatttgtgt
    40261 gcgatgtctg ccttgttctg ggcgataaaa atcataaggt agatcgtagc tagaattcac
    40321 agcagtgtaa taaacaggat tatatccgac cttttctact aacaaagtga gttcttggac
    40381 taattttgaa tcccggttgc cagaaaaagt agcagatttc agtggtttac gattcaaaaa
    40441 acgtttagct aaatcattta aaataggatc agcagattca gaccattgag taaagtaagt
    40501 gcccaagacc ccatcatcaa gtttgaggta ttcttctaaa gtaaagcttc cgtcaagaaa
    40561 tggcagaagt aattgagaat ggagttcaaa actgctggca tcttcttgat acaactcgtg
    40621 tgcgcgatga agcagatgct ccaaaattac ttccatacca cgggaaacag gatggaagta
    40681 cacttgcaca tacatttgat atcggctaac gatataatct tccactgcat gcatgccact
    40741 catggaaaaa gcgatcccgc cttcataagg acgaatcaca cgtaatattc gggtaagatc
    40801 aaatgttcca tattctgttc cagtgaaata agcatcccga agcaaatagt ccattcgatc
    40861 tgcatcgatc tgactagaaa tcatttggac aacttgtggg ttggggtaag ttttttggat
    40921 cacactagct accttttcag gaaaaccttc ttctactcgg ttaagaatct gatacacttc
    40981 tgtttctgga gaagtgatga tctctacagt gatggcttca tgattcgtat ggaagatata
    41041 ttcaaatgta tgagagtaag gaccatgacc gacatcatgc aacagtgccg cacataaagt
    41101 caccagccgt tcctgatcat cccagcctcc gttgcctatt ttttcttttg aaaaatttcg
    41161 agaaaagata tcgcagattc gtcttgaaat ctcataaacg cctaatgaat gagtaaaacg
    41221 gctatgttct gctccgtgaa aagtgaaaga agaagtgcct aattgtttaa tgcgtcgtag
    41281 acgttggact tctttcgaat tgatcaaatc taagattact tgatgctgga catggatata
    41341 gttatggact ggatcacgaa aaactttttc cataggcagc atttgatatt tataaggggt
    41401 tgtcataatg tagctccttt atgttattac gttgttccat tctctggatt tggttgttcc
    41461 attgctccag ctggatttct ttttttagcc agtcggtaga atcctgtaaa tcacttgcag
    41521 aatacagctt ttcaaaagct tttgcaaatg cttctttgac ttcttttaca aaaaggggtt
    41581 ggtcaagcag ttcttcaagt gttgccattg tagcaggatc cactgcagga tagccatttg
    41641 taccaaagtc ttcttttaaa gcagattgat aaaatcgctt catgacttgc ccacgttttt
    41701 cctgattacc gttgacactt aagtacatca taacagaaat cccatttttg atccgacgct
    41761 gagcgatacc ggcaaatttt ttgccatgga tgcttaaatc ataagttcca ggacaataag
    41821 aatgggtgat ttcgaatgct tgtatcggtg cctttggaaa agcgtattta gtcaatagga
    41881 gcatttgctc gtaagcgtca tctatggtta ttttttttgt gtcactttgg gggaaaatca
    41941 aagaaatatt caaaattcct tcatctgata cgatccctaa tccacctgaa tttctgatca
    42001 ctggagcgta acctgcatct tccagtgttt ggatcccgtc acttagaaaa ggagttcgaa
    42061 catccttcat acctaagatg actgtgcagt catattgcca gaaatgtaaa aagatttgct
    42121 ggtgttcttt agaatattcc gttaatatat ctgttaatgc aaaaggggaa aagtcgtttt
    42181 tttgataaat gtgctgatct agtcgaatcg cagggttcat tcaaccggct cctttgtata
    42241 aattcatatt ttctacaata ttatactcta aaatcaaaga gttgttttgg aaaaaaggtt
    42301 ttctgtaaaa atggacaagt tggttgacaa aacaaaagaa actaggaaca atgtagctat
    42361 gagaagtaaa ggagaatgaa taatggaatt atcacaagga acaccgattt caatcaaatt
    42421 gcgtacaaaa gtaaaacagc aaggggaagt gcaagatttt tattttgatt tgaaagggca
    42481 aatggtgaca attggcgata cgctgtacat acgttataaa gagattcagg aggagacggg
    42541 cgatgagatt cctgtaacga tcaaattagt tccagatggt catgtacagc tgatccgtgc
    42601 aggagaaatg cggatgcgtt tgaaatttgg ctataaagaa cggttagaaa catcctatcg
    42661 aacaccatac ggtatgatcc agattgctac ttttacgaaa gaactgcatg ttagtttgaa
    42721 agaccgtccc acagcaggga aggttcgaat cgattatgat ctgttcatgg gaccggaaaa
    42781 aatcggcgaa tattatttga ccttggattt tacagcgtaa atataaaaga aaagtttgat
    42841 tttttgtgtc tgattttgta tgataaggag tagactgtga aaggacgtgt cctgattgga
    42901 aattagtgta tttgaaggtg caaacaaaag cgaattatca atgatcgaag tagcacacgc
    42961 gatcttagaa caacgtggcg atgtcatgga tttttctgat ttagctaacc agatccaaaa
    43021 ctatcttggg aaatcagaca gtgaaattcg tgattcactc gcacaatttt atactgactt
    43081 gaatattgac ggcagcttta tctcattagg ggataatcgt tggggcttgc gttcatggta
    43141 tgctatcgat tcgatcgatg aagaagtaaa ccatggaatg gacgaagagg atgaagatac
    43201 tccacgtcgc cgtaaacgca agaaagtcaa cgcctttatc aatgatgatg aagacgcgat
    43261 cgattacaat gacgatgacc cagaagatac agatctgaca gaagaagatg acgatgatct
    43321 gtttgatgac gatgatgatg aagatgaaga aatcgctgct tataattctg acttgcaaga
    43381 aatcggagca gatgacccga cagatgatga agaagacttg ccaggaaata tcgaagaaga
    43441 tttaagtatc atagacgaag acgatgatga tgaagattat gaagaggaag aattttctga
    43501 ctctgaaaaa gaataaacat tattttctta cgagaggttg tgacagagac gatcagccta
    43561 tcagaataag gaggtgtgac acgatttttg tcacaccttc ttttttgtat ataaaaatcc
    43621 caagtaaata cataaaaaat aaaaaaattg aaacttttag cgcaccttgt acgtcatatt
    43681 aagtgaggca gaaaggagtg gagaatgatt tttactggat ataagaaaaa acggcagatc
    43741 gaaaaatacc gtcacctgct gaatggactc atcgaaactg attatcaaaa aatgttccgt
    43801 atcacgatga attacgtaca tgataaagaa gaggccttag atgtgatgca agatagtttt
    43861 cataaagccc tgaactattt tgaaaaagaa aaagagatcg agcattttag tgcatggttt
    43921 tatcggatat tgatccgcac ggcattagat agttggcgca gacaaaaaag gacgcctgtg
    43981 gacttatttg aaattcaaga tatcccccaa cagttacctt tagaaacttc cgttgcagag
    44041 ctccatatga ttttagataa aatagacagt ccggaaaaag agattctgat cctctacttt
    44101 tttgaaggat ttcgtttgaa agaaattgcg actatcttgg atatgaatga aaacacagtt
    44161 aaaacgaaaa tgtaccgctc attgaatgct ttacgtcaaa tcctagaatg aaggagagaa
    44221 gagtgccatg tattcccaaa aagaaaattt aaaaaaacta aagaaaactt ataaagaaca
    44281 agcaattccc aaagggctta aagaggagat ccgccagcgt tttattatcg aagagcaatc
    44341 atttataaaa gcaaagcgga gaaagagacg tctccaaggg ttcggagtat ctttggctat
    44401 cgtaatgatt acaacaagta gccttctttt taatagtcaa gttcgaagct ttgcagaaga
    44461 tttacccatc ttaggatcag tcattgaatt gatcttaggc gaacgcttta ctgatcgatc
    44521 tgaaaaaatc gatattcagg taccgaagat caatacacaa aatgagaaag aaaataaaac
    44581 aattcatgga ttaaatcaaa aatactttcg cgaaggacaa gcagattttg aaaaagctga
    44641 aaaagaatat ggaaattttg aaacggatca ttaccaagtt ttgggagatt atcagaaaat
    44701 cgtagacgat aaccggtttc tcgtgattga aaggcagatc acccaaacag cagcagatag
    44761 ccatgttgaa aaaagatacg acacaatcga caagaaaaac agtgtccagc tctcacttcc
    44821 acttttattc aaagatgaca cctatctatc tgttttgaca aaagaagtca aacggcagat
    44881 ggccgaacaa gtcaaggaag atccatctaa gtactattgg actgagcaag atattcaaga
    44941 agggacgata gaaaaaccaa cacttgttac gcctacacga agtttttatt tgaacaaaga
    45001 gcatcaatta gttttgactt tttctcaata cgaaattgct cctggttata tgggtacacc
    45061 agaatttgtc attcctaagt ccgtgacaaa aacgattttg gcatcggaag attatttgga
    45121 tcattagacg agaagtagtt gcgactagca gtttcaattt tcaagtaagt acaagtaaat
    45181 aataagaaga gaaaaagaga aagaagagat atagtgaaaa gaaattattt agttatcagt
    45241 attattgctt tatccgtgct tttgtttttc gaaattactt cggtggcctc cttgatcacc
    45301 gaagtaaaag gacaaacaca ctcttcggag cattcgtcac aatctttcaa acaatcagaa
    45361 caatcaacca ttaaaagcca atcaactgaa acagctaacg tcaaagaagc cattcaagaa
    45421 tcagcggaaa aggtacaaag tcagtcatca caatcaacac aagacagtac aaaaacgagc
    45481 cgagatccgg ctgtcaaaag cgtcgcaatc agctttgatg atggaccagg agcgaccaca
    45541 acaccgcagc ttctgcgaat cttaaaagaa aaaaacgtgc atgccacttt tttcgtctta
    45601 ggagaaaata cggcgcagca tcctgaaatc gtgaagcaga cagctgaagc agggcacgag
    45661 attggcaatc acacatacga tcatcagaat ctggccactc tttctgccca gtcgatgacg
    45721 gaggaagtga cgaaagcaga cactgagatc aaaaaagtca ctggcaaaac ccccactttt
    45781 gttcgtccgc cctatggttc tgtcacgaat gtaggagcaa cgatcatcca gcgaccgatc
    45841 atcgaatggt ctgttgattc agaagattgg aagacaagaa atcctgattt gattttgcag
    45901 aagatccaag caacagtata cgatggggca attattttat tccatgatat ctatcctgaa
    45961 acgattcgtg ccgttcctca agtgatcgat tatctgaaag agcaagggta tcgcatcacg
    46021 acagttgggg atttattagg gcatccaacg gctgtcgaga actattatgg cagaaacgat
    46081 catcggccag ttcagtaagt gagacaagta tctttaataa ataacacatt ttaataagta
    46141 gttgaacaca taactacctt acttgcaaag gcttaacaat atctatacag gtacaacaaa
    46201 aaactgtcca ccaattttct ttggcggaca gttttcactt aaaaataaag aagcaactat
    46261 tcgtaaatta tgctaaaata gcagtagaac gcgtcctgag ggaatcgaac ccccgtctca
    46321 agaaccggaa tcttacgtga tatccactac actaaggacg caagcactgg gataattgta
    46381 actaaacaga taaaaaatta caaggggatt ggacaaaaaa atgaaatttg agcaaaattt
    46441 ttcacaaaaa cagcagcaga cacagaaact agccatgacg caacagttgc aacagtccat
    46501 ccaagtttta caatataaca gtgaggagct gttggcattc gttgagaatc aagcaatgga
    46561 aaatccattg gtggaagttg ttgagccgga atggcagcca gattacataa aagcttcttc
    46621 atcttcttat gaaggagaag agacaaatta cctaaatcag attcctgata caaaagggtc
    46681 tttatttgat tcattgatcg aacaagtcca tttgaattac cgagatactt ttttgaggaa
    46741 aatcgttctt tatcttgtag aatacatcga tttgaacgga tttttgacga ttagtttaga
    46801 agaagccgga aaagagattg gagctacgcc tatccaaatg ctcgatgcgt tgactctgat
    46861 tcagcaatta gaaccagctg gagtaggtgc acgtagtttg caagaatgtc tcatgcttca
    46921 aacagaacga gatgattatg cgccggaatt agcttatatc gtgttggaag aatgttttga
    46981 ggaactggtg gagcgaaaat ggaaagaaat cgcacaacgt ttttctgttg atctacatgc
    47041 tgttcagcag atattcgact atttacaaac gttgagtcca agccctggcc ggattttcga
    47101 ccgtagcagc gaattgtaca ttattcctga tgtccgggta ttagtggacg acgataaaaa
    47161 tgtacaagtt atctcaaacc gaaaaaatca gccaaatata cgctttcaag agagttactt
    47221 caaacaaatg tcacaacaag cagataaaga aactgaaaat tatttaaaag aacggaaaca
    47281 ggaattcgaa tggttgaaga aaacgatcct acaacgtggg gatacaattt tgcgggttgc
    47341 tcaagtcatt gtttcccggc aaaaagcttt ctttatcgac aaggaacgtc caatcaagcc
    47401 tcttacgtta aaggaagttg caactgagat agatgtgcat gaatccacgg tcagtcgtgc
    47461 agtcaacggg aaatatttgg aaacagactt cggtgtattt gaattaaaaa aatttttcac
    47521 tacacgaatt cctacgaata gtacagaaca gacagaagac ctttcagcag atacagcgaa
    47581 gaaaaagctg caggaattag tcgatcaaga agacaaaaac aagccgttgt ctgaccagaa
    47641 attggttgaa ttgctgaaaa aagatgagat agcgatctca agacgaacag tagcaaaata
    47701 tcgtgattta ttaggaatcc cgagttcatc aaaaagaaaa cgttatgata actaatcagt
    47761 caaaagacta gaaaaagtat ttcacttttt ctagtctttt tagttgaaaa acgagagcaa
    47821 aactgttaga cttacagtcg tgaggttgag atttcccttt attgatgtga aattcgaata
    47881 gttaatttct ttttttatcg tatatgggtc gttttaagtc tacattggac gtaaagtgtc
    47941 caactaagga gatcgctatg ctggatgaaa taaaaatgat tgaatctgtt gcaccagata
    48001 ttatcgaagt gttgcaagaa cgctataaaa ttttacgaaa tatctattgg atgcagccga
    48061 ttggacgtcg aagtttatcg gaaagtatgg ggatcacaga acgagtattg cgaacagaaa
    48121 cagatctttt gaaaaatctg aatttgatcg acacctcaaa aagcggtatg acgctgacaa
    48181 ctaagggcga agaagtttat caaagccttg aaaacttcat ggatcagctt ttaggtacgc
    48241 atcaaaccga acaacagttg gcagaatatt ttggtaacca acgctgtatc gttgtttcag
    48301 gaaacagcga agagcagacc aaagtggctg atgcattcgg cgaagcgctg agcgaagccc
    48361 tagaccgact acttccagaa ggcgagaata tcatcgctgt gatgggagga actactatgg
    48421 ctgtggtagc cgaacaattg tctaatctgg aaaataagaa acggcataac ctgtttgtcc
    48481 ctgcaagagg cgggattggt gaagcgataa ctgtacaggc aaattctgtc agtgcaagaa
    48541 tggctgctaa agcaaacggt aaccaccgtg cactttatgt tccggaacaa ttaagtctgg
    48601 caacttacaa ttctttactc aatgagccat ctatccaaga agtcttaaac ttgattagtg
    48661 aagcgaattg tgttattcat agtattgggc gtgcattaca catggcagca cgtcgtaaga
    48721 tgactgaaaa agaattagtc atgctgaaac aagcaaatgc tgttgcggaa tcttttggct
    48781 actttttcaa tgaaaaaggt gaagtcgttt ataaggtccc tagaatcggc atagaattgc
    48841 aagatttgga aaaagtcccg atcatcatgg caatcgcggg cggaaaatca aaagccaaag
    48901 caattcgagc ttatatgaaa aatgcaccaa aacaaacgtg gctcatcact gatgaagctg
    48961 ctgcaaatga gattttaaaa ggggtaaccc tttaaaataa atattttttt gattttcata
    49021 aggaggaaat cttaaatgac agttaaagta ggtattaatg gttttggacg tattggacgt
    49081 ctagcattcc gtcgtatcca agatgtagat ggaatcgaag tagtagcaat caacgacttg
    49141 acagatgcta aaatgttggc acacttgtta aaatacgaca caactcaagg acgtttcaac
    49201 ggaacagttg aagttcatga aggttcattc aacgtaaacg gaaaagaagt taaagtatta
    49261 gctaaccgca acccagaaga attaccatgg ggcgaactag gcgtagatat cgttctagaa
    49321 tgtactggtt tcttcacttc taaatcagca gctgaaaaac atttaacagc tggtgctaaa
    49381 cgcgttgtta tctctgctcc tggcggaaac gatgttccaa caatcgttta taacacaaac
    49441 cacgaaacat taactggtaa agaaacagtt atctcaggtg cttcatgtac tactaactgt
    49501 ttagctccta tggctaaaac attgaacgac aaatttggtg ttgttgaagg attaatgaca
    49561 actatccacg cttacacagg tgaccaaatg actctagacg gacctcatcc taaaggtgac
    49621 ttccgccgtg cacgcgctgc tgctgcaaac atcgttccta actcaacagg tgctgctaaa
    49681 gctatcggtt tagtaattcc tgaattgaac ggtaaattag acggagctgc tcaacgtgtt
    49741 cctgtaccaa caggttcatt aacagaatta gtaacagttc ttgaaaaaga agtaactgtt
    49801 gacgaaatca atgcagcaat gaaagaagct tcaaacgaat cttacggata caacacagac
    49861 gaaatcgttt cttcagatat cgttggtatg acttacggtt cattatttga tgctacacaa
    49921 actaaagtaa tgacagttgg cgacaaacaa ttagttaaaa ctgttgcttg gtacgacaac
    49981 gaaatgtcat acactgcaca attagtacgt actttagaat acttcgctaa cttataagat
    50041 agacaaacgt acaagtgtaa attatagaca tgtacattta aaagcgggga agcaatcgcg
    50101 cttcttccgc tttttttgat aataagttta ttcaggagga aataaaatgg ctaagaaaac
    50161 agtgaaagat atcgatttaa aagacaaaaa agttcttgtc cgtgttgact tcaacgttcc
    50221 tttgaaagac ggcgtgatca ctgacgacac tcgtatcaaa gcagcattgc caacaatcaa
    50281 ctacgttcta gaacaaggcg gaaaagcaat ccttttctct caccttggac gtgtaaaaac
    50341 agaagaagat aaagaaggaa aatctttagc tccagttgca aaacgtctag gcgaattatt
    50401 aggtaaagaa gtaacattcg tacctgaaac tcgcggagaa caattagaag aagcaatccg
    50461 caacatgaat gacggcgacg ttgtcgtatt cgaaaataca cgatttgaag atattgacgg
    50521 taaaaaagaa agcaaaaatg atacagaact aggtaaatac tgggcttcat taggcgatgt
    50581 atttgttaac gatgctttcg gtacagctca ccgtgcacat gcttctaacg taggtatcgc
    50641 ttcaactggt atcccaacag ttgctggatt cttgatggaa aaagaaatca agttcatcgg
    50701 tgaagcagta gaagaaccaa aacgaccaat gattgcaatc cttggtggcg caaaagtttc
    50761 tgataaaatc ggcgtaatcg aaaacttgat tcctaaagca gataaaatct tgatcggtgg
    50821 cggaatgact tacacattct acgaagcaaa aggaatcaag atcggtaact ctctagtaga
    50881 agctgataaa gtggaactag caaaagaatt aatcgaaaaa gcaggcgaca aacttgtctt
    50941 gccaatcgac aatgtctgtg caccagaatt ttcaaatgat gttgaaacac aagtaatcga
    51001 aggagacatt cctgatggtt tgatggcttt agacatcggc ccagcatcag taaaattatt
    51061 tgctgataca ttacaaggtg caaaaacagt tgtttggaac ggacctatgg gtgtatttga
    51121 aatgagtaac tttgctaaag gtacaatcgg tgtttgtgaa gcaatcgcta acttagaagg
    51181 cgcaacaaca atcatcggtg gcggagactc agccgcagca gcagaacaat taggatttgc
    51241 tgacaaattc acacacatct caacaggtgg cggcgcaagc ttggaattgc ttgaaggtaa
    51301 agaattacca ggactagcag caatcaacga taaataaacg accaagtttg ctcaattctg
    51361 acgagtaatc gatcaaaagg tgaagggagt tttcatgact ccctagccat ttttcaataa
    51421 attaaggagt gtgttcctca atgcgtaaac ctattatcgc aggtaactgg aaaatgaaca
    51481 aaactgcatc agaagcaaaa gaatttgctg aagcagtaaa aaacaaaatc ccttcaaatg
    51541 acaaagttga ttcagtcatc ggatctcctg cattattctt acaagaatta atgacatcag
    51601 ctgaaggtac agaactaaaa atctcagcac aaaactgcta ctgggaaaac tcaggtgcgt
    51661 tcactggtga aacttcacca gcagctcttg ctgatctagg tgttcattat gtgatcatcg
    51721 gacattcaga acgtcgtgaa tatttccatg aaacagacga agacatcaat aaaaaagcga
    51781 aagctatctt tgcaaatggt atgacaccaa tcctatgctg tggcgaatct ttagaaacct
    51841 atgaagcagg caaaactgct gaatggatcg aaggacaaat tacagctggt ttagctgatc
    51901 tttcagctga acaagtgtca aacatggtta ttgcttatga accaatctgg gcaatcggta
    51961 ctggtaaatc agctgacgca caaatcgctg acgaaatttg tggagttgta cgtcaaacag
    52021 ttgaaaaact ttatggaaaa gaagtatcag aagcagttcg tatccaatac ggcggttctg
    52081 taaaaccaga aaatattgct gaatacatgg caaaagaaaa tgttgacggt gctttagtcg
    52141 gtggcgcaag cttgcaagca gattcattct tgtcattgtt agacgctgta aaataattgt
    52201 tgaaaatttg cgaaaaatgc aagaaatgtt tgcactaatg agcaaaatta actaaaatcg
    52261 tatatgaggg aaatccctta ggaaaaaaca aactcaaagg agagacaaaa catgtcaatt
    52321 attactgatg tttacgctcg cgagatctta gactcacgtg gtaacccaac aatcgaagta
    52381 gaagtataca cagaaagcgg agcttttggc cgcggaatgg ttccttcagg tgcttcaact
    52441 ggtgaatacg aagcagttga attacgtgac ggagacaaag ctcgttatgg cggtaaaggt
    52501 gtaactaaag ctgtcgacaa cgtaaacaac atcattgctg aagcaatcat tggctacgat
    52561 gttcgtgacc aaatggctat cgacaaagct atgatcgctt tagacggaac tcctaacaaa
    52621 ggtaaattag gtgcgaacgc tattttaggt gtttctatcg ctgttgcacg tgcagctgct
    52681 gactacctag aagtaccttt ataccactac ctaggcggat tcaacacaaa agtattgcca
    52741 acaccaatga tgaacatcat caacggcgga tcacatgctg ataactcaat cgacttccaa
    52801 gaattcatga tcatgcctgt tggcgctcca acattcaaag aagctctacg tatgggtgct
    52861 gaagtattcc acgcattagc ttcaatcttg aaagctcgcg gattagcaac ttctgttggt
    52921 gacgaaggtg gatttgctcc aaaccttggt tcaaacgaag aaggttttga agtaatcatc
    52981 gaagcaatcg aaaaagctgg ctatgtacct ggtaaagacg ttgttcttgc tatggatgct
    53041 gcttcttcag aattctacga caaagaaaaa ggtgtttacg tactagctga ttcaggcgaa
    53101 ggcgaaaaaa caactgacga aatgatcaaa ttctacgaag aattagtttc taaatatcca
    53161 atcatctcaa tcgaagacgg attagacgaa aacgactggg acggattcaa gaaattaact
    53221 gacgtattag gcgacaaagt tcaattagtt ggtgacgact tgttcgtaac aaacactcaa
    53281 aaattatctg aaggtatcga aaaaggaatt gctaactcaa tccttatcaa agtgaaccaa
    53341 atcggtacat taacagaaac tttcgaagct atcgaaatgg ctaaagaagc tggctacaca
    53401 gcagttgtat ctcaccgttc tggtgaaaca gaagattcaa caatctctga tatcgctgtt
    53461 gcaacaaacg ctggccaaat caaaactggt tctctatcac gtactgaccg tattgctaaa
    53521 tacaaccaat tactacgtat cgaagaccaa cttggtgaag ttgcagaata caaaggtttg
    53581 aaatctttct acaacttaaa aaacaaataa ttcttttcta atgaagatac atgatcgact
    53641 attgaaagat agtcgagtat gatcacttag ttaagtaatc gaactctcta cttgctgaaa
    53701 tatcagcagg tagagagttt tttttgcaac tagcttctgt atatgatgtt tacaaagaat
    53761 ggtacaagaa aagatcatcc ttgaaaaagg aaagctaaca ataactagca tcatataaga
    53821 gcttttaagg atagaacagt agaataggaa tctatgagca agtcctctcg tataaataaa
    53881 ataggaggga agtagcagca tatttttcat aaagtggctc tctttcttca tttttacttt
    53941 ggttgctcct atttgaaaat tcgagcacac tcaaatacaa taaaaagaaa tggcaaggga
    54001 gaggattaga tgaaaaaaga agaaaaaatc gcgattttac aagagatcat ccgaattaaa
    54061 tcagtgaatg gaaacgaagg tgaagtagca gcctatttga ataagctttt ggcaaagcat
    54121 gacataacag gagagattgt ttcttacaga gatggtagag ataatttgat tgctcgttac
    54181 caaaagggcc aatcaggaaa agtgttaggc ctatctgggc atatggatgt cgtggcggct
    54241 ggtgatgaat cgtcttggac ctatgcaccc tttgcagcag aaatccatgg gaaccgtttg
    54301 tacggacgtg gtgctacaga tatgaagagt ggcttggcag caatggtgat tgccatgatc
    54361 gaactgaaag agtcaggaaa accatttaac ggaacagtca aattattagc cactgtcgga
    54421 gaagaagtgg gtgaactagg tggggaagag ctcacgaaag caggctatgt agatgactta
    54481 gatgccttga tcatcggaga gccaactaat tacagtttga tgtatacgca catgggatca
    54541 atcaactata cagtcacctc gcacggaaaa gaagcgcata gctctatgcc agaccaaggt
    54601 tataatgcaa tcaatcacct aaatgaattc attacgaaag caaatgctga aatgaatcac
    54661 ctcgctgaaa caatcgagaa tcctgtccta ggaaaaacaa tccataatgt tacattgatc
    54721 agtggcggga atcaagtcaa cagcatccca agccatgcgc agctccaagg gaacattcga
    54781 tcgattccag aatacccaaa tgataaaatc attgcattgc tgcaatcaat cgtcaatgaa
    54841 ttgaatcaag agacagacta tcatttggaa ttgatgatcg attacaacaa aatacctgtc
    54901 aaagctgatc cagattctcc tttgattcat tgcattcagc aacaattcag ccagccatta
    54961 cctttagttg gagcggcagc aacaacggat gcagccgaat ttacgaaagc taaccattcc
    55021 ttcgactttg tcgtctttgg gcctggtgtc gttactttgc ctcatcaagt agatgagtat
    55081 gttgaaatcg ataattattt ggatatgatt gaaaaatatc aaggaattat tttatcctac
    55141 ttagcgtaag atttttttaa taaatgaaaa aacagagcca gattagcatt attttgctaa
    55201 tccagctctg tttattcagc ctatttttct ttttgaatat atcaagcgtt gtggcaacat
    55261 agtgatgact aatgaaacaa cgacgataga caacaaacga tcaaggtagt ctgtacctgc
    55321 ctgtaccaag atcacacttg ttgtctgact taaacctaac ccatgtaata gctgaacgat
    55381 catactggat cctgaggagg tgatcccgcc aaataactga acggtaatga tcgaagaaac
    55441 gatcgttcca ggtaccgaca aaatcaaagc gagtaataac agtttcaagc tgtttttatc
    55501 tttgccgaga tatcttggca aaatcaatcc agcaagcaag cctgtgagaa tttggattgg
    55561 cgaataatac agagaaaaaa tatctgtagt cactccactt aaaataccgc tggacaatcc
    55621 tgtcagcatt ccaggtacag gcccaagcaa tgcaccagca aaaatcgttc cgatagaatc
    55681 gagatagatt ggcaaacgaa gccataaagc aatcgttcct ccaatataat tgatcccaat
    55741 acacaaagcc atcactgtaa gtacgcgagt tgccattttg tttttattca ttttgttagc
    55801 ccatctttaa cctttccaaa tctttcataa tcgtttcttc ttgtgcattt aaaagaacgg
    55861 ttaaaaactt tcggaaaaaa agacgagtat ctacttttgt cataatttta ctgttagcag
    55921 gtttctgcca aaattcataa cgatcaacca atgtttgtcc acgacttatt ccttgagttt
    55981 ccacagcagt gaagcttttg aaaccttcac agatggcccc ctcgataaaa taagcaacag
    56041 ctaacggatc attgatgaca catcctaaaa ttctttcttg tttccagtgg aagtcaaaat
    56101 aaaaacgagt gatcgctttt agatactctc cctcttcagg attcatttga cagcagtatt
    56161 cgaggatagt cggtgtcaag acgatttctc ttgtcacatc taacccaacc atttctatcg
    56221 tttgtttgag attctcgaat acataagaag ctgcttcagg atcacaccag taattgtatt
    56281 cagcaactgg cgaacagtta ccatggcttt tgtaagttcc acccatcgag acaaaacgat
    56341 ccatatgttt cccaatattt gggttgactt tcaaagcaaa agcgatattg gtcaaaggac
    56401 ccaaagcaat gactgatgta tttgtctttt ctttgaaata atcagccaaa aaatcaacgg
    56461 catggagagg ttctgcctgt tttctcaaga tcatcgggaa atttgtttcc cctaaaccat
    56521 ccataccatg agtgtcttgt gcactgatga aaggttgctt caaaggtttt tccattcctt
    56581 gataaacagg aatgtctaaa cgatcacagc gttccaggca tttcagcaca ttctgcgtac
    56641 ctatatctgc agggacattc ccacaaacta cggtaatagc aactacttcg atatcagggg
    56701 atttgacagc taatgataaa gctaaagtgt cgtcgatccc tggatcgcaa tcaataatta
    56761 cttttcgcat tatttccaat ctcctttctt tagagatact tagtttttta ttctgggaag
    56821 tttccgaacc agtccaagac gagcgtcttg attataatgc acgaaattag tatactggct
    56881 tttattgcga atgtaaatgc tctcttacaa gtaaatctat tgaggagaac tttaagtaaa
    56941 tgatacaatg aaaaagaaat ggaatttacg tgtgccgaaa ataaagaatc ctatggatcg
    57001 gtacattgga taatagttag attatagttt ggcagaaagc ggcgggtgta caatggttat
    57061 tttttatttc attcttattc tgataattat agggatcagt taccattttc tttcttattt
    57121 ttatgcaaag aaattagtaa gagcgggagt acagagagga tatgactggt atgaagacac
    57181 tggtcatcgt ttgatggacc ctgctgcagt cacgtcagta gaaaaaaaac gacaaaaatt
    57241 agaagaagag tgtgaaagct tttgggagca gggaacaccc aaaacaatca aaagttatga
    57301 cgggttgaaa ctagctggtc agatgttcat ccatccaaat aagcagaata aatgggtcat
    57361 ttgcgtacat gattaccgaa gcacagggaa aagagacatg tctcatatag gtaaaagata
    57421 tgcagagaaa ggattcaacg ttcttgtacc tgatttacgt gcgcacggag aaagtgaagg
    57481 agaaatcatc ggaatgggat ggctagatcg gctagattta attgcctgga tccaactcat
    57541 cttagatgaa cagccgaatg cgtccattat tttacacggc ggatcaatgg gagcttctac
    57601 gatcatgatg gcaagtggtg aaaaacttcc atcagcggtc aaaggattta ttttagacag
    57661 cggatatgtt tctgtttatg cagaattccg atatatgtta agtaaaatca ctgtctttcc
    57721 taaaaaaatg gtcatgagat atgcgaatca ttatgcccag aaatacgccg gttactcctt
    57781 aaagcaagca tcagctacga gacagcttgg cagcaaccat ctgcctttat tggtcattca
    57841 tggtgaaaga gatcattttg tccctacaga agcagcgtac acgattcaaa atgctacggc
    57901 aggggataaa gcactgctgc ttgttccaga agcagaacac ttggaagcat cgatgaaaga
    57961 tccgaaaacc tattggacag tgattttttc atttattgaa caaagaataa cgatgaatta
    58021 attttctctt cttttttgta agtaattcga ggataaataa ttgtttatag atcaggagac
    58081 tgctaaaata aggtaggaat aaaaaaatat cagttatttg aggagtgcgg catatggaaa
    58141 tcaaagaaga aaaaaatcgt cttgctttat tcaatgatga acaacaagag atcggagaaa
    58201 tgacatggtc agatgcgggc ccagacatca tgatcattga ccatacattt gtagatccag
    58261 catatcgtgg tcaaaagtta gctgaaaagc tagtgtatac tggagtagaa ttagcaagac
    58321 gagacgggaa aaagatcatt cctttatgca cttatgcaaa aaaagagttt gaaaagaaac
    58381 cagaatatca agacgtctta cgtcagtcat aagaataaca gctgaaagtt ttgaactttc
    58441 agctgttatt ccatttatat agagttgtca cggactttta tctatgataa agttaaagag
    58501 acgatatctt ttgggaagga ggctgcgata tgtataattt aattttggga atcgtgatcg
    58561 ttttatcgat tgttatggtc attgcgatta tgatgcagcc aagcaagcaa aatagtgcag
    58621 cgagtgcatt taccggcggt gcggatcaac tattcggcaa acaaaaagct cgcggctttg
    58681 aagctgtcat gcagcgatca actgcagtta tgggagctat ctggatgatc ttattatttg
    58741 tcctagcata tttatcttcg aagtagttga ataagcctct cgcaaaacgg cgggcggctt
    58801 tttttattgc aaagagaacg cttaagaaga agttatgaaa gaaactatgg taaaatgagg
    58861 cgaaagaggt gagacgagtg agacaattac caaaacccct ttatgcaaaa catggaaagc
    58921 gagcggtttt gctgcttcac gcttactcag gaagtccaaa cgatgttcga atgctcgcac
    58981 gatttttgga aaaagcagat tatacagttt atgcgccgct ttttaaagga cacggaacaa
    59041 tggagccata tgatattttg caagaaaaag cagaaagctg gtgggcagac actaaaaaag
    59101 ccatccattt tttacagtct gagcagtttt ctgatattgc cgtattagga ttatcaatgg
    59161 gcggcatctt tgctgtacga gcactagaag aagaatcagt gattggcggc ggttttttct
    59221 gttcgccttt gtctcctgta aaaacaaacg tgcctgaaaa ctttgaaaaa tacgtacgtc
    59281 aagtgctgaa gacagcaggt aaatcagaga aagaaatcaa tgaaaaagca gttgcttacc
    59341 gctcgttagc tgaacaacaa ttaatggata tacaagatca ggcagcaatc gtagaaagta
    59401 ggttgtcaga tatccaacag ccgatatttt tagctcaagc tgggaaagat gaaatgatcg
    59461 accctaatgg cgtatttgaa actgcacgca agttgagccg tcagcgagtg acacttcgat
    59521 ggtatcctga aagtggtcat gtgattacag ttggtacagc aagacgcgaa ttagaaaaag
    59581 acgtcttgga atttttagaa aaattacctt ggaatgagga ataaatatga caaaagaaac
    59641 gataaaagag aaaattctct ttttcatgga aagcagtcgc aaacgcagtt tttctatgga
    59701 agaaatcgct gaaggtttag ggttccaaaa aagcgatgat tttaaattac tagtacaaac
    59761 gattgctcaa atggaaagag aacagagtat agttttcaat aaaaaaggaa aagtgaaact
    59821 tcctttaaaa ccaatcttga tcgaaggaac atttcgagca aatgaacgag gatttggatt
    59881 tgtaacgatt gatcccgaag aagatgacat ctatatccca aaagaagcga ctggttttgc
    59941 aatggatgga gacaccgtag caatcgatat catgaagcga gcaaatacag atatggatcg
    60001 cggagcagag gggaaagtag tcgagattcg agaccgggcg actactcagt tagcagggga
    60061 attcgttgct tattcagaag aagaaataca agaaacggat ctttacggcg ttgttatccc
    60121 gaaagataga aagctcaacc aatttaaagt atatgcagca gcagagggag ttcgtccagt
    60181 tgacggaagt attgtgctga tcgaactgac ccattaccct gaaaaagggt atgcgactag
    60241 tttagaaggg ataatcaagc aagtgattgg tcataagaat gaccctggca tggatatcct
    60301 ctcaattgtc gtggctaatg gtatccctac gaaatttcct gatgatgtat tgtctgaagc
    60361 agatgaagtt ccagatcaaa tcagcgaaaa ggatataact ggacgtagag atttaagaaa
    60421 tcagctcatt gttacgattg atggagaaga tgcaaaagat ctagatgatg cagttacggt
    60481 taaaaaatta gataacggta attattttct tggagtacac attgcagatg tttcttacta
    60541 tgtgacacaa ggcagtcaat tggacagaga agcatatgaa agagggacaa gtgtatattt
    60601 gactgatcga gtgattccga tgatcccgca acgtttatcg aatggtatct gttcactgaa
    60661 tccccatgtt ccaaggctga ccatgagttg cgaaatggag attgatccaa atggacaagt
    60721 agtctctcat gatattttcc caagtgtgat ccaaacaaca gaacggatga cctacacagc
    60781 tgtcaatcaa atcttagaag atcaagacga agaaacgatg caacgctatg ctcagctcgt
    60841 acctatgttc caagaaatgg gtgaattgca tcgaatcctt gaaacgatgc gaatcaaacg
    60901 tggcgcgatt tcttttgagg atcgcgaagc aaaaatcctt gttgatgctg aaggacaccc
    60961 aaatgatatc cagctaagaa gcagaggaat tggtgaacgc ttgatcgaat ctttcatgct
    61021 tgcggccaat gaaacggtag ctgaacatta taataaatta aatctgccgt ttatttaccg
    61081 aatccatgaa cagccaaaag aagaaaaaat gcagcgcttc tttgattttg cttcagcttt
    61141 gggcattctg gtccgaggaa cgaaaggaac gatcacacca aaagatttac agcatgtgat
    61201 cgaaggagta gaagacaaac cagaagctgc agttatcaat actatgttgc taagaagcat
    61261 gcaacaagca cgctattcag aagacaattt tgggcattat ggcttagcgg cagattacta
    61321 cacacacttt acatctccta ttcgacgcta tcccgatcta atcgtccatc gtctgatccg
    61381 ttcttacagt gaagataaaa gtgaaagcaa tcaaagttcg tgggctacgg aacttcctga
    61441 aattgcagat catagttcta agatggaacg tcgtgcagta gaaacagaac gtgaagtaga
    61501 ttccatgaag aaagcagaat tcatgatgga caaagtgggg gaagaattcg atgggatcat
    61561 cagctctgtt gtgaaattcg gcctgtttat cgaactgccg aatacagtag agggattgat
    61621 ccatatcaat gaattgaaac aggactactt ccattttgtt gaaaatcatt tagctcttgt
    61681 aggtgaaaga actggtctga cttttaaaat cggacagaaa gtgcgagtaa aagtagtcaa
    61741 agctgatcca gatgaacgag cagtagattt tgaacttgtt tccgcagaag aggttacagc
    61801 gttggaacgg ccaaaaacac gaaatggaaa atcaggaaaa cgcgaaggaa aacaagcagg
    61861 aaaacgccca gaaagaaatg gcaagaagaa caaacgatat agcgatagta agcaaacgtt
    61921 cggtaagaaa aaagggaaga agccatttta caaaggtgtt aaaaagaaga aaaagaaaaa
    61981 ataaaatgag ttggaggaaa cagctatgcc aaaaggcgag ggaaaattaa ttgcacaaaa
    62041 caagaaagct cgccatgatt attcgatcat cgacacgatg gaagcaggga tggtcttgca
    62101 aggaaccgag atcaagtcga tacgaaacag ccggatcaat ctaaaagatg gatttattcg
    62161 cgtccgcaac ggagaagctt tcttgcataa tgttcatatc agtccttatg aacaaggaaa
    62221 tatttttaat catgatccgt tgcgcacgag aaagttatta ttacacaaaa aacaaatcat
    62281 ccggcttgaa aatgaattga aaaatactgg aatcactgtt gttcctttaa aagtctatat
    62341 tcgtaacggc tatgccaagg tattgattgg tctggcgaaa gggaaaaaat cttatgataa
    62401 acgggaagat ttgaaacgaa aagatatcga tcgacaaatt gatcgaacat taaaaaattt
    62461 ctctagataa tttcattatc ctttttcgca tattcggtgc ttttgctttt acttaatgat
    62521 aaaatttgtt agcatttaat ctgataaaac atgattatca taggtttttt cttagatcag
    62581 gagcaccgtg tataaagaaa aattcgcttc gtttttgact gaaataaaaa agtgtctaat
    62641 tttcatgaaa atgttttgaa ttttctgttt catggtggta tgataccgtg tggttagaaa
    62701 ccgattggaa aaaaccagat acgcacatga attgatttta tgtgaatttc ggggaaaaga
    62761 ggtgaaatgg attggatgaa cgctcgctaa cgttccacat tggaccaatt tggtttgatg
    62821 gtacagtttg tataatggtg ttactgacct gtttgattgt tttcttctta gcttactttt
    62881 ttacaagaaa tcttaagttg aaaccaacag gcaaacaaaa tgcgatagaa tgggtcattg
    62941 attttagtcg aggaatcgta acagataatc tgcctagaaa agaattgagc aatttccatt
    63001 tgttggcatt tacattgttt ttatttgttt ttgttgcaaa caacatcggt ttagtaacaa
    63061 aaatcgtttt acctaacgaa acaacacttt ggaaaagccc gacagcagac ccgtttgtta
    63121 ctttaacttt ggcatttata atgatcttac ttactcactt atttggggtg aaaaagttag
    63181 gcttcaaagg atatttcgta aattcgttct tgaaaccata tagttttatg tttccgatga
    63241 aactgattga agaatttaca aacttattaa cacttgcttt acgtctttat gggaatattt
    63301 atgcggggga agttttgcta accttgattg caaaaatggt aataagctta ggctggttct
    63361 cattgccgtt agcaattcca ttagagatgg tctggatcgc attctccttg tttatcggaa
    63421 gcatccaagc atttgtcttc gttactttat ctatggttta tatgagccat aagattgaag
    63481 tggaagaata atattcgttt taaaaacaaa ctactattta tctaatttag gaggaaaaca
    63541 attatgaatt atatcgcagc agcaatcgca atcatgggag cagcaatcgg agccggttat
    63601 ggtaacggtc aagttatctc taaaacaatc gaatcaatgg ctcgccaacc tgaaatgtct
    63661 ggtcaattcc gtacaacaat gtttatcggg gtagctctag tcgaagctgt tcctatctta
    63721 ggggtagttg tcgccttgat tctagttttt ggtgtttaat tgaatcagta ttaaggcaga
    63781 aacaatttgg tttgttactg cttttttaca tgaaaactag aagtacttca aagaaaggaa
    63841 ggctcgccta tgctgaatca attggcaatt gcagaagttg gcaatgcgat gttaggaaat
    63901 gtcatcgttg tcagcggctc atttttgata ctactggctc tcttgaagca ttttgcttgg
    63961 ggaccaatca gcgatatttt gaaaaaacgt gaagacaaga tcgccaatga tttggattct
    64021 gcagaacaat ctcgcatcaa ctcagcgaaa atggaacaag aacgcgaaca acaattgtta
    64081 gcctctcgtt ctgatgcagc tgatatcatc aaaaatgcga aagaaagtgg agaattaagc
    64141 cgccaaaata ttttgaagga tgctcaagaa gaagcagctc gtctaaaaag taaagcccaa
    64201 gctgatatca ctgtagaacg tgattcagcg ctgaactctg taaaagacga tgttgcagaa
    64261 ctatctcttc aaatcgcgga aaaaatcttg aacaaagaat tatctccaga aatgcacgaa
    64321 tcattaatca atcaatatat cgaaggtcta ggttcttcaa atgaaactag ataaatatac
    64381 agtaggaaga cgttacggga aagctttatt tgaactggcg atcgattcaa ataaagcaga
    64441 agaaatttat caagatctcg taagcttacg tcaaatctat gaacaagtac ctggattagg
    64501 taatatgtta agtgatgttc gtctagaacc tcatgaaaaa cgagaaatca tggacaagct
    64561 tgttagtggc tatgatggaa tcgttaaaaa ctttttagaa gttgtttatg cgtataaccg
    64621 aatggatgat cttttgttca tgatcgaaga atatgaacgt cgatatgatg aacatcaagg
    64681 tttgctgttg ggaagtgtca caacagcagt tccactttca gacgaacaac gaatacaatt
    64741 agaaaagaat gttgcaaaaa caatgaacta tcaatcagtc gaattaaaac aaatcgttga
    64801 ttcttctatt attggtggcg cgattgttga agctaaccat cgagtaatcg acggaagcat
    64861 tcgcacgcaa ttagaaaata tgcgtaatca attaaataga tagtacaaag aggtaggtga
    64921 atcgaatggc catcaaagca gaagaaatta gtgccttgat taaagaacaa attgaaaatt
    64981 atcaaaacgt gctttcagtc gaagaaatcg gtaccgtaac ttatgtaggt gacgggatcg
    65041 ctcgtgcaca tggtttagaa aacgcgatga gtggtgagtt gcttgaattt tcaaatggct
    65101 catacggaat ggcgcaaaac ttagaatcaa atgatgtagg tatcattatc cttggcgatt
    65161 tcgagtccat tcgtgaagga gataaagtaa aacgaacagg aaagatcatg gaagttccag
    65221 ttggagaggc cttgattgga cgggtagtta atccgctagg tcagccaatt gacggactag
    65281 gtgaaatcgt tactgacaaa gctcgtccag tagaagcaat ggcaccaggc gttatgcaac
    65341 gtaaatctgt taacgaacca atgcaaacag gtctaaaagc aatcgacgct cttgtaccaa
    65401 tcggacgcgg ccaacgtgaa ttagttatcg gtgaccgtaa aacagggaaa acttccattg
    65461 cgatcgatac gatcatcaac caaaaaggtc aagatatgat ctgtatctat gtagcaatcg
    65521 gacaaaaaga ttctacagtt cgtacacaag ttgaaacatt gaaaaaatat ggcgcaatgg
    65581 attacacaat cgttgtgaat gccggtgcgt ctcaaccagc gccgttgctt tatatcgcac
    65641 catatgctgg tactgcaatg ggtgaagagt tcatgtacaa cgggaaacat gtcttgatca
    65701 tttttgatga tctttcaaaa caagctgttg cttatcgtga actttccttg ctgcttcgcc
    65761 gtccaccagg tcgtgaagct tatccagggg atgttttcta cttacactca cgcttattgg
    65821 aacgtgcagc aaaattaagt gatgatttag gtggcggttc aatgactgcc ttaccatttg
    65881 ttgaaacaca agctggagat atctctgctt atatcccaac aaacgttatt tcgatcactg
    65941 atggacaaat cttcttagaa agcgacttgt tctacgcagg tactcgtcca gcggttgatg
    66001 ccggactatc tgtatctcgt gtagggggtt ctgcgcaaat caaagcaatg aaaaaagttg
    66061 ctgggacttt acgtctagac ttagcaagtt accgtgaatt agaagcattt acacaattcg
    66121 gttctgactt ggatgcagca acacaagcaa aactaaatcg tggacgccgt acagtagaaa
    66181 tcttgaaaca aaaattgcat gcaccgctag ctgttgaaaa acaagtagtg attttgtatg
    66241 ctttgacaca tggattctta gatagtatcc ctgtagacag tattttagac ttcgaacatg
    66301 aattattcga atatctggat accaatcatt cagatatctt tgaaacaatc cgtacaacaa
    66361 aagatcttcc agaagaagaa gcgttgaaca gtgcgattca ggaatataaa gacatgttct
    66421 tagctacaaa aggaaataat tcctctacag aagataaatt gaaatccatt caaaatgcat
    66481 agtgaggtga gatgaatggg tgcttcatta aatgaaatca agacacgtat cgcttcaacg
    66541 aaaaaaacga gccaaatcac gcgggcaatg cagatggtgt ctgcttctaa gttgacaaaa
    66601 tctgaagctt cttcacagaa gtttcaggtt tatgcaacaa aagtaagaga aatcgttacg
    66661 catttgactg ctactcagtt aaatgatatt gcctcagaaa atcctagagg ggatatcaat
    66721 tacaacagca tgttgctcag ccgtcctgtt aagaaaacgg gttatatcgt catcactgca
    66781 gatggcggtt tagtcggtgg atataacagc tcgatattga aacaaacgat gtctatttta
    66841 gaagaagacc accaatcacc cgatgattac gtgatgatcg caattggcgg aactggtgca
    66901 gacttcttta aagcacgcgg tatcaatcta gcatatgagc tgcgcaatct atctgatcag
    66961 ccaagctttg atgaagtccg caaaatcgta aatatggcaa caactatgta ccaaaacgaa
    67021 gtattcgatg aattatacgt atgttataac catcatatca attcgctaac tagtcagttt
    67081 cgtgtagaaa aaatgctgcc aatctcagac ttagatccag aagaagcaac tactttcgaa
    67141 caagaatata tttttgaacc ttcaaaagaa gaaatcttgt ctcagttatt gcctcagtat
    67201 gctgaaagtt tgatctacgg tgcgatcgtt gacgccaaaa cagcagaaca tgctgctggt
    67261 atgacagcaa tgaaaacagc aactgataat gctgctaata tcattgatga gctgacggtt
    67321 tcttacaacc gtgcaagaca aggggctatt acccaagaaa ttaccgaaat tgttgccgga
    67381 gcttcggcac tagaatagta ttgagattgg aggaaaaaag atgagttcag gcaagattgt
    67441 tcaagtaatc ggtcccgttg tcgacgtgga attttcttta gaccaatcct taccagatat
    67501 caacaacgca ttagttgttt ataaaaatga cgaaaataaa tcaaaagttg ttcttgaagc
    67561 agcgttagaa ttaggggacg gagtgatccg gaccattgcg atggaatcaa cagatggttt
    67621 acaaagagga atggaagtca ttgatacagg caaagcaatc tctgttcctg taggtaaaga
    67681 aacattaggt cgcgtattca acgtactagg agatacgatc gatttagaaa cacctttccc
    67741 agaagatgcg gaaagaagcg aaattcataa aaaagcacca gcctttgacg aattaagtac
    67801 aagtacagaa attttggaaa cagggatcaa agttatcgat ttgcttgccc catatttaaa
    67861 aggtgggaaa gtcggactat tcggtggtgc cggtgttggt aaaaccgtac tgatccaaga
    67921 actgatccat aatatcgccc aagaacatgg tggtatttct gtatttaccg gtgtaggtga
    67981 acgtactcgt gaaggtaatg acttgtatta tgaaatgaaa gattcaggag ttatcgaaaa
    68041 aacagccatg gtgttcggac aaatgaacga accaccaggt gcacgtatgc gtgttgcttt
    68101 gactggtttg acgattgcgg aatatttccg tgatgtagaa ggtcaagatg tactgttgtt
    68161 tatcgacaac attttccgtt tcactcaagc tggatctgaa gtatcagcct tgttaggacg
    68221 gatgccttct gcggttggtt atcaaccaac attggcaaca gaaatgggtc aattgcaaga
    68281 acgtatcaca tctacgaaaa aaggttcgat cacatcgatc caagcaatct atgtgccagc
    68341 cgatgactac actgacccgg cgccggcaac agcattcgcc catttggatg cgacaaccaa
    68401 cttggaacgt aaattaacag aacaagggat ttatccagcg gtagatccat tggcttcttc
    68461 ttcaagtgct ttagcacctg aaatcgtggg agaagaacat tataaagtag caacagaagt
    68521 ccaacacgta ttgcaacgat atcgtgaatt acaagatatc attgctatct taggtatgga
    68581 tgaattatcc gatcaagaaa aagtgttagt ttctcgtgcc cgcagagtcc aattcttctt
    68641 gtcacaaaac tttaacgtgg ctgaacaatt tactggtctt ccaggttcat atgtccctgt
    68701 agaagaaaca gtgaaaggat tccgcgaaat cttggaaggc aaatacgatg atcttcctga
    68761 agaagctttc cgaagtgttg gccgaatcga agacgtcgta gaaaaagcga aaacactagg
    68821 ctactagaaa ggggtgcccc atggatcaat atttaacagt aaatgtggta actcctgccg
    68881 gtttggtcta tgatcaccat gcagctatcg tcgttgcacg tacgacagct ggtgagcttg
    68941 ggattttgcc taaacatgca ccaatcatcg ttccattgac gattgatgaa gttcgtgtaa
    69001 aacgaacaga ttcagatacc cacgtcgatt ggatcgctgt taatggcgga atcatggaag
    69061 ttcgtgataa tgttgtttca atcgttgctg atagtgcgga acgtgaacgt gatatcgatg
    69121 tatctcgtgc ggaacgtgca aaacaacgcg cagaacgcca aatcgaagaa gcaaaagcaa
    69181 aacaagatac gaacgaattg aaacgggcaa ctgttgcgtt gcaccgagca atcaatcgta
    69241 tcaaagtatc taagcactca taaaatgaga tgcggatgtt tatccgtgtt taagaacagt
    69301 aaaaagaggt tatgacagaa gtggtcagct tcaagacata agaaggaatt tacgaaaatt
    69361 gcttctcaaa tttttgtgaa atctcagctt atttttcgaa gaagctactt ctggaacacc
    69421 gtatatcgga ggttgtgaaa tcagcgtttt gtcctgagta ttagagaaac aaatggaaaa
    69481 tagttcctca tattttgccg ttttttgagc taataccgag ggtcagatga ttgaacaccg
    69541 tttatttgga ataagggact gcgacaagac ttttgtctca gtcccttttt ttgcatattt
    69601 ttagcattta tttcctaaaa aatgtaaggg gattcctata tttttaagta tacttgtttt
    69661 tccttttata cattttatgg tattatcatt ttattagtta ttataaaaca atcgttagaa
    69721 aggacgtcat tatgcaagta tacggaattg atgcggtgct tcgaatcgtg agtcatttgg
    69781 cgtttatcta cttagccttc tggtctttac gttcgttacg cattgaaact tttttcagac
    69841 caatgcataa tacgcaaatt agaatggcaa tcgtactttt ttcaattttt ttagggtaca
    69901 ctgcaagtaa ttttttctta gaagttatcg ctttatgccg aaatcttttc gttagcctgt
    69961 aaattttaaa aaaaggtact attttaaaag caaggatgtt ataatagaaa agattttgag
    70021 taagtgtatg ctcattggaa ttttttggag ggaacaacat ggaagagatc atcgtaagag
    70081 gtggcaatca attaaatgga acagtaagaa ttgaaggagc taaaaatgct gttttgccta
    70141 ttttagctgc tagtttgtta gcagaagaag gtattacgac attagacaac gttccgattc
    70201 tttctgatgt cttcactatg aatcaagtga ttcgtcactt aaacgtagat gtagattttg
    70261 atgaacaaaa gaatcaagta acaatcgatg cttcaagaca attagaaatc gaagcgcctt
    70321 atgagtatgt tagtcaaatg cgtgcttcaa tcgttgtgat gggtccgcta cttgccagaa
    70381 atggacatgc aaaagtagct atgcctggtg gatgtgcgat tggtaaacga ccaatcgatt
    70441 tgcatttaaa aggatttcaa gctttaggag caaaaattat tcaaaaaaac ggctatatcg
    70501 aagcaattgc ggatgaattg atcggtaaca cgatttattt agatttccct agtgtaggtg
    70561 ctactcaaaa tatcatgatg gctgccgtaa aagcaaaagg aacaaccatc attgaaaacg
    70621 tagctcgcga accagaaatc gttgatttag caaacatttt gaataaaatg ggcgctcaag
    70681 tctatggagc tggtactgaa acaatgcgta ttgaaggcgt ggatcattta catgcagtca
    70741 accactcaat cgtacaagat cgtatcgaag caggtacctt tatggttgct gctgcaatga
    70801 cacaaggcaa tgtgctgatt gcagatgcta tctctgaaca taaccgccca ttgatttcta
    70861 aattgatcga aatgggtgca gaaatcattg aagaagaagg cggagtccgt gtcatcggac
    70921 caaaacatat cttacctaca gatgtaaaaa cgatgcctca tcctggtttc cctacagata
    70981 tgcaagctca aatgacagct atccaattag ttgcagaagg tacaagtgta gtgactgaaa
    71041 cagtgtttga aaatcgtttc caacatttag aagagatgcg ccgtatgaac gctcatgtca
    71101 aaatcgacgg aaatgtagca atcatggatg gaaaccatga attgcaaggt gcagaagtat
    71161 atgcaacaga cttgcgggca gcagcagcat tagttttagc tggcttgaaa gcaaatggaa
    71221 tcacacgtgt gcgtaacttg aattatctag accgtggata ttataatttc catatcaaac
    71281 tacagcaatt aggtgcagac gttgaacgtg tagacatgga tcaaacttct gctgaaaaaa
    71341 cagcacaaac gattgcttaa ggaagtggct gaatgagtaa ccaacgatat atcttattaa
    71401 ctttgataaa gattttagtg gtgatcttat tgcttatcct tctttttgtg gccggaacga
    71461 tgatcggata tggtgtcatc ggtggcggca atccatttaa agtattccag ccaagtttgt
    71521 ggattcatat tcgagacttt tttcattgat aaataagaat cacagtggtt ctagtcgata
    71581 tgaagtgagc catgaagcag aacatgacaa aagaaaacag aagggaacgt tgacgttagt
    71641 cgcgatccct ttttttagta aaagaaaaga aggaatctaa ttgatgaaga agatattgat
    71701 ttatttagtt agaggatatc agcgctttat ttcgcctgca tttccaccta gctgccgtta
    71761 ttacccaacc tgttccaatt atatgataaa agcaattcaa acccatggtg cactaaaagg
    71821 gacggtaatg gggactgcac ggatcttacg ctgtcatcct tttgtcaaag gcggtatcga
    71881 ttatgtacca ttgacattcc aattaacgcg aaataagaaa gataaaaaag aaccagatta
    71941 taaaaaggtt gtgaaaaata cgagtagcac tgagcgataa agaaacaatt tggaaaatag
    72001 cttcttatat tttgcaaaat tgtgagttat tgccgaagtg ttggattttg aacaccgtca
    72061 aaaaaaggtt gtgaaaaata cgggtagcac tgagcgataa agaaaaagag gaaaattatt
    72121 gtcaaagtaa caactccgca actacttata tgggggacaa aaaatgatcg aagaactaaa
    72181 caagaaagat ttaccatggt ccttgttatt agatgcagat cctgataaag aaaaagttca
    72241 agtatatgtt tccagaggga gtggctggat atggaaagaa aaagaaaaaa caataggtgt
    72301 actgatctat gtggcaaggg aaaaagaata cgaaatcgtc aatgtagcag tagccccaac
    72361 gtatcaagga aaggggattg gcggaaaatt acttgagaca gcttttcaga agctttcaca
    72421 actcgcttcc agtcaaactc agatcatcat acgaaccggc agtactagca gtgcggcgtt
    72481 acatctctat caaaaaatgg gctatgtgga gattggtcga gtcaaagact attttatcca
    72541 tcattactct gagcccattt ttgaaaatgg agatcaatta agggatcaag taattttagc
    72601 aattcactta cctaaaaata gctttaacta ataaactttc aattcgagaa aatgctttca
    72661 aatgctaaat agatacatta caatagcttt agcaaacaaa aaggagaata tttttatggg
    72721 aatattagtt tttgattttg gtggatcggc tgtcaaatat ggttgttggg atggcaaaga
    72781 gattaaaggt aagggacaat ttgcaacgcc tgaatcttgg gaagaaatga aagcgcaatt
    72841 atttcaagtt tataaaaaaa tactcgtttc ttttgaagtc gaaggaattg gaatcagctc
    72901 tcctggagta gtgaataatg agaaacaggt gattgaggga atcagtgcga ttccttatat
    72961 tcatggattt aatattttcc gagatttgga aactctgttt caactcccag taacgattga
    73021 aaatgacgcc aactgtgccg gaatggctga attttatgaa ggtgctgccc gtgattatca
    73081 agatgttgct tttgttgtgg caggaactgg gattggcggg gcgttgttca cgaaaggaca
    73141 aatcaataaa ggggcacatc tttatggtgg agaatttggg ttgatgttct taaatggcga
    73201 taagacattc agtaaacttg gtacagcggt acagatggct tggcgttatt gtgaacgcaa
    73261 aggtctcgat aaaaattctt ataccggaaa agatgtcttt gaattagcag aaactggaga
    73321 tgcaatagca aaagaagaag ttgagagttt ttatacgtat cttacaaagg gattattcag
    73381 tattcaattt tcgtttgatc cagaagtgat cgtattaggc ggcggtgttt ctgcaaaaga
    73441 agggctcatt gatgagatca aaagccgaat gaagaagctg acagaacaat tcgatctgca
    73501 tgatttcgaa ccgcagattt tattatgtga atacagaaac gatgctaatc ttgtaggtgc
    73561 agcagcaaac tatctcgctg tacgtcaagg ggagaattaa gagctttaga gaaggtgcag
    73621 cttgcataaa agaagtgaat gaaatgaata ggagattttt acctaaggaa tgttttattt
    73681 gctgcagtat gataaaatat ctgagaggtg aaaatgatgt caaaaaaaaa ataaagatgt
    73741 tgaagtgcgt atagaagaag tgaaaaaaga tatcaaaggt aagaattatg aagtcactca
    73801 gttatttata gggaaaaaaa tgattggtga gatcttagcc tatgggccaa aagaatatga
    73861 aattttcttt ggtgaagaag attttggaaa agaaaaaagt cttgaaaatg cgatagaaac
    73921 agtgattcga cactggaatc tgcacgaata aaaaaatatc aaaaaaactt tcaataaagg
    73981 gttgcaaaaa tctggaaaat taggtattat aactaagtca ggttgataca aacctttcgg
    74041 aggagtagcg aagtggctaa acgcgacgga ctgtaaatcc gttccttagg gttcagtggt
    74101 tcgaatccac tctcctccat ttcattgggg tatagccaag cggtaaggca agggactttg
    74161 actccctcat gcgttggttc gaatccagct accccagtat accacaatcg taagctctcg
    74221 ttagttcgag agctcttttt tttgctttgc taccttgttc cttgaagatt ctgctgattt
    74281 aagatagagt taagttaact acaagaattg gagggatcca catgaaatgg aaagaaaaag
    74341 tagacgaagc agctgaaaag ttatatgatt tggtcaaatc agaaaaatac aatattgaag
    74401 tgaatattcc gaaaaaaggc ggaaaagcgg tccaggtaaa atcaaaacgc ccaacgaatc
    74461 atacaaaaaa atggatggct aaaaaccgct aataataaca aaagatccat aagtcggcat
    74521 tttcatcgat tttagggtct tttgttattt tctaggttga acatatctaa aaaattgttt
    74581 ctgacaatag gagtaggaag aacgatgtgt gtctaaatcc tctgttgatg gatagaaacc
    74641 tttatctttt tcagttgtga atcaggtata taccagttat aatagaagaa acgaaaggac
    74701 gggtgtacgt tatgtcgaat caattacctg tatatataca gattcatgac caattaaaaa
    74761 atgaaatcga acaaggtata tggaaagtcg gagaccgtct tccttcagaa agagaattag
    74821 cagtgaaatt caatgtcagc cgtatgacgt tgagacaagc aattcaaaac ttggcagatg
    74881 aaggaatctt agaaagaaag atcggttcgg gtacatatgt tgcgcgagaa aaagtacaag
    74941 aaaaaatgtc tggtgcaaca agttttacag aaattatgga atcgcaaaat cgagtaccgt
    75001 ctagtcggac aatctcttat ttcttgactt cgccaagctc aagtgaaatg gaaaaactaa
    75061 acttgagtaa agatgacacg atcttgcgaa tggaacgtat tcgtttcgca gatgatgtcc
    75121 ctatttgttt tgaagttgcc agtgtgccac aaaagctgat cgatggctac agcaaagcag
    75181 agattactga atcgttgtat cgcacgctag aagaaaaagg cgggaaaaag atcggtccag
    75241 cgaatcaaac gattactgct gtgttggctt ctgagaaaat tgctgactat ttagaggtaa
    75301 aacgaggaga tgcagttctt cgtttgcgcc agatttctta ttttgaagac ggtacgccgt
    75361 ttgagtatgt gcgtacgcaa tacgtaggaa atcgttttga gttttatttg gaaaaataaa
    75421 aaacaggtga tccctgattc cttacttaga aataaaagag aatcagaatc acctgttttt
    75481 atatatgatc agttaccagt tgctcgtgat aagaaacagg accctcttca aattggactt
    75541 gtccgttcag cagctcaatg atggattctt taaagtggtc agcacttttt tcatctacag
    75601 cacagatgac gctaacttga tcagtatatt ggatttcttt tataaaaaaa tgttggagtt
    75661 caagataatt ctgtaatttt cctagttgcg gatacgtgat catcacagag atctcctgtt
    75721 gcaaggtacc ttctacgatt ccaatgtcag acaatgcttg agagacagca tgagtgtatg
    75781 ctcgtattaa tccgcctgtg ccgagtttcg ttcctccaaa atatcgagtg actactgcag
    75841 ctacattgat cagttgattt tttttgagga cttccaacat cggtacgcca gccgttccac
    75901 ttggttctcc atcatcgctg cttcgctgga tttcattttt ttctccaatg atgaaggcgc
    75961 tgcagttatg gttcgctttc caatgttctt tttttatttc ttgaatgaaa ctttttgctt
    76021 ggtcctctga ttctattcgt ctaagagaac agataaagcg tgattttttg atctcaatct
    76081 cactttgtcc attttctttt attgtacgat agcgctcgat catcttgtca cctctttttt
    76141 tcattttctt tattcagtat aaataaagtt ctaggttgtt tcaacactgt aacggttgcg
    76201 caatcgctgt agtatgcgat aataaagaca aaggtaggtg gatctgggga tgcaggaacg
    76261 aatgaaaaag tacgatgcaa ttacgcatta tttgaagaac aatggcggct ctcaagtaac
    76321 gttgaccttt acccaatttg acgaactgct gtttcccagt aacggacttc ccaaaacagc
    76381 aagggaaagt acagattggt gggcaaatga ttataaacac cctgaaaaag gtgcctatgg
    76441 ctggataaat gcaggctatg aagtagttgt catcaatttg gacaaagaat atgtcgtgtt
    76501 caataaatta gtgaaatcta gttggctatt tgattaaata aaccgcgttt agaaaacgtt
    76561 gacaaatttc tttcttttta tataatagag taacagacgc gaagaaaacg tttgcgtagt
    76621 ttgttttaaa aaggagagaa aagtatggct aaaaaaacaa tcatgcttgt atgttcggct
    76681 ggtatgagca caagtttact agtaacaaaa atgcaaaaag ctgctgaagc aaaaggaatc
    76741 gactcggata ttttcgctgt gtccgcttct gacgcagata acaatcttgc aaataaagat
    76801 gtagatgtac tgttattagg acctcaagtt cgctttatga aagctgattt tgaaaaacgt
    76861 ctggaaccaa aaggcattcc tttagacgtc atcaatatgg ctgattatgg tatgatgaat
    76921 ggcgaaaaag tgttagatca agcaatcacg ctcataggtg aataaataga acagtataac
    76981 tatcgaacaa gcgatccaaa aaatagatcg cttgtttttt cgtatatttt tttagggcga
    77041 ataatatgaa tcatttttgg ggtagaaggc ttctgacgag agatattaaa gcaatagact
    77101 gtgaggaggt aaatttacca aattatgaga agatcgcagc agtggaacgt ttgggcaact
    77161 ggattctttg tcatcgctgt ggaatgagga cgtccgtcat tgatggacag cttgcagatt
    77221 acggttattt ttgtacacat tgtctatatt tagggcgatg cgacactcaa caagatttat
    77281 atttgtttga tcagcctgaa gcaaaacctc gagaagtcgt ctttttttgg acaggacagc
    77341 ttactgaaaa acaaacggaa atcgcaaaga gaatactttg ccattcagaa aaaagacatc
    77401 atcttatttg ggctgtaaca ggtgcaggga aaacagagat gctttatcct attttagtgg
    77461 aaactttaaa agctggagga agagtagcga tttgtacacc gcgagtcgat gtttgtaatg
    77521 aattgttttt acgctatcgt tatgtttttc cagaagaaaa aatcacgttg ctccatggga
    77581 atacagcaac ggcttatacc tttacttctt ttgttatctg tacgattcat cagctatacc
    77641 gtttttatcg gtcctttgat ttaatagtga tcgatgagat cgatgcgttt ccttataacg
    77701 gggatgcagg attagctcat gctgtgcaaa cagcgattaa accagacgga cgattcatct
    77761 acttaagtgc cacacctgat aaaaagttac taaaggaaat caagcagacg tttgacatcc
    77821 acaaacttgc tttgcgcttt catcggcgtt tacttcctga acccgtcttg gttttcatga
    77881 ataattggcg acaaaaatgc aagaacaaga agaagataaa atctttggtg cggatcattc
    77941 atcaattaat taaagaaaac catatccttt tattttgtcc aagtatcacg atgatgcatc
    78001 gtttgaaagc cacacttcaa gaggctcttc cgagatatga gatcacagat gtttcttcaa
    78061 gagacaatca gcgggcggaa aaagtccaga aaatgcgaga agcaaaatat gacatactgt
    78121 taaccacgat gatccttgaa cgtggagtca catttgaaag aatatccgtt atcgttttag
    78181 gagcggatca tccggttttt actaaatctt ctttggtaca aatcgcagga agagccgatc
    78241 gtaaagggcc ttatacgaac agtcaagtat actttttcta tgaagaaaaa actgcagcta
    78301 ttcgaaaagc ttgtcaggaa atcaaagaaa tgaatgaaga agggaagaag atgctgtgag
    78361 gtgcagttgc tgcagtaaag atatcgtcca aaatttaaca ttcagcgaga ttattggtgt
    78421 ttcgaaatac agattacctc agacttgttc agtttgtcgc gcacaatttc atttattgga
    78481 aacaagaggc tgttctggct gtcaaaaacc aatccatttc aatctagaga gtacgaaaaa
    78541 gaaagtaaag tctattcccg tttactgcag tgactgtcaa gaatggaaga agaaatatcc
    78601 gacctatgat tttcagcacc gtgccttttt tgtgtacgat gaaaatatga aggcctggct
    78661 caatcaatac aagtttatgg gagatatccg actagcaggc acctttgcat ataaatggac
    78721 gcagataaaa aaagaatacc cgacatacat ctattgtcca atacctttat ctgaaaaaag
    78781 gcgaacagaa agaggattca atcaagtaag cgagatgttg aaagcagcaa gaattccttt
    78841 tcagatgcta ctcaaaagag agaagcatct gctggctcaa gcaaaaaaca cgcgaaagga
    78901 aagattggag atgcctcaac cttttgaact tgcagtcacc ttttctaaga tacaaaataa
    78961 aaaaatattg attattgatg atgtctatac aacaggacag actcttttcc acgcagcaga
    79021 ttgtttgcag gtcgcacagc cgaaaatcat ccgaaccatt tctttagcaa gatgaattag
    79081 atgtggaaat ttgatagcga tttaatttgc aaataaccta gagttcgata taatagaatt
    79141 aagaagaggg aaagagtggt ccttctcctt cttgattgtg gtagacgaaa ggggtaattt
    79201 ttatgtttag atataatgta cgcggcgaaa atatcgaagt aactgaagcg attcgcgact
    79261 acgttgagaa aaaagtaggc aaactagaac gctatttcag tgacgcaccc gatgcaacgg
    79321 cgcatgtgaa cttaaaagtt tatacagaaa aaacagcaaa agtggaagta acgatcccat
    79381 taccttatct tgtattacgt gccgaagaaa cttctccaga tttatacgca agtatcgatt
    79441 tggttgttga caaattggaa cgccaaatcc gcaaattcaa aacaaaaatt aatcgtaaat
    79501 cccgtgaaac gggcatgaat actgcagatg ctactgcttt attcaatgaa gaggacgaaa
    79561 acgaaaatga ttctgaatta gatatcgtac gtacgaaacg cctttcattg aaaccaatgg
    79621 atagtgaaga agcagtctta caaatgaaca tgctgggaca taacttcttt atttttgaag
    79681 atgcagaaac aaatggtaca agtatcgttt accgccgtaa agatggaaaa tacggactga
    79741 ttgaaacaga ctgatcagcc ttacttaaat aacaacgaaa acttgcagca gctactgaca
    79801 gctgccgcaa gtttttttga gtttcctcct cttttagatg aaatatgaat aaattatgaa
    79861 gttcttactt taatacgctt aagatatttc aattatctat aactaatgat aaaatgaaaa
    79921 gtaaagtcta catagtctgg ataatacaca gaaggaaaag gagattacac aacgcatggc
    79981 caatttgatt cgttcactta tcgaaaacga taagaaagaa ctaaaacgtt tagatagcat
    80041 tgcaaaaaaa gttgaagcat acgctgacca aatggcagca ttaactgatg aacaattaca
    80101 ggcaaaaact gctgaattca agggcagata ccaaaaagga gaaacattag atcaattact
    80161 tccggaagct tttgcagtcg tccgagaagc agcaaaacgt gtattggggt tatatccaca
    80221 ccacgtacaa ttgatgggtg gaatcgtgct tcacgatgga aatatccctg aaatgcgtac
    80281 tggtgaaggt aaaaccttga ccgcaacgat gccagtatat ctaaatgctc tgactggcga
    80341 aggggtacac gtagttaccg tcaatgaata tttagcaacc cgtgactcga cggaaatggg
    80401 cgaactttat aatttcttag gattaacagt ggggttgaat atcaactcaa aatcttcgga
    80461 tgaaaaacgc gaggcttata attgtgatat cacttatagt acgaataatg aattaggatt
    80521 tgactacttg agagacaata tggtcgttta ccgccatcaa atggtacaac gtccgctgaa
    80581 ttatgccatt gtcgatgaag ttgactcaat cttgattgat gaagcgagaa cgccgctgat
    80641 catttcaggg caagcagaaa aatccacagc tttatataca agagcagaca acttcgtgaa
    80701 acgtttgaaa gaagaagaag attataaaat cgatgtacaa tcaaaaacaa tcagtttaac
    80761 cgaagcaggg atcgaaaaag cagaagaaac attcggtttg gataacttat acgacattga
    80821 aaatactgca ttgacccatc acttggatca agcattgaga gccaactata tcatgctttt
    80881 agatatcgat tatgttgtcc aagacggaaa agtactgatt gttgaccagt tcactggtcg
    80941 gatcatggat ggacgccgtt attcagatgg acttcaccaa gcaatcgaag ctaaagaagg
    81001 cgtagagatc gaagacgaaa cgaaaaccat ggcgacgatc actttccaga actatttccg
    81061 tatgtacaag aaacttgcgg gaatgactgg tacagctaaa acagaagaag aagaattcag
    81121 agaaatttat aacatccaag tataccagat tccgacaaat cgtccggtta tccgtgatga
    81181 tcgtccagat ttgctttacc caacattaca aagcaagttc cacgctgtcg tgcaagatat
    81241 caaagatcgc taccgcaaag gtcaacctgt gttagtcgga actgttgcgg ttgaaacatc
    81301 tgagttatta tcagatatgc tgaatcaaga acgtattcct catgaagtgc tgaatgcgaa
    81361 aaatcacttt aaagaagcag agatcatcat gaatgctggt caaaaaggtg ctgtgacgat
    81421 tgctaccaac atggctggtc ggggaacaga tatcaagtta ggacttgggg taagagaact
    81481 tggtggtcta gcagttatcg ggacagaacg acatgaatct cgtcgtatcg ataaccagct
    81541 tcgaggacgt gcaggacgtc aaggagaccc tggtatgtca cagttctact tgtcattgga
    81601 agatgatttg atgaaacgat tcggttcaga acgaatcaaa tctttcttag atcggatgaa
    81661 gatcggtgag gaagatgctg ttatccaaag caagatgctg acgaaacaag tagaatctgc
    81721 acaaaaacgt gtagaaggaa ataactatga cacacgtaaa aacgtcttac aatacgatga
    81781 tgtgatgcgt gaacaacgtg aagtaatcta taaacagcga caagaagtaa tcatggaaga
    81841 aaaaagctta tccaagccac taatgaacat ggtcaaacgg acaatcagtc gtgtagtaga
    81901 tgcgcataca caattagaga aagaaaattg gaatttggaa agtatcatcg attttgccgg
    81961 cagtactctt gtccatgaag atagtattac tcttgcagat atcgaaggaa aaacagctca
    82021 ggagatcaaa gagtatctaa acgaacgagc acaagaagta tttaatacca aagcggctca
    82081 actaaatggt ccagagcaac tgttggaatt tgaaaaagtc gtgatcttgc gtgttgtgga
    82141 ctctaaatgg acagaccata ttgatgcaat ggatcaatta cgtcagtcaa tcggcttacg
    82201 tgcttatgga cagaacaatc cattagtcga atatcaaaca gaaggctata agatgtttga
    82261 agatatggta ggcgccatcg agtatgaagt cactcgaatc tttatgaaag ctgagatccg
    82321 tcaaaacgta cagcgtgaac aggtttctca aggaacagct tctcactcag aagacggaga
    82381 tgccaaagaa aatagtaata ctagcgcgaa aaaacagcca atccatgtga acaaggtcgg
    82441 aagaaatgat ccttgtcctt gtggaagcgg gaaaaaatat aagaactgtc atggaaaaaa
    82501 tgcaaactaa tttctgacag caggattggt gagacaaatt ctttttttaa gaattcgtct
    82561 caccttcttt ctgttatttg ctgattctgt tagactagat ataatgaaaa aagtatagtg
    82621 aaagaaggaa aaaacatgga aatatccgaa attcgaaatc tcctgacaga aatgcaggaa
    82681 aaggtcacaa gcttcaggag gtctctttga cttagaccag ctggaagaag acattgcgga
    82741 agcagaagca aaaatggctg aacctggttt ttgggatgat agcgaagctg ctcaaaaagt
    82801 gatcagtgaa aacaatgcaa ataaagaaac ttatgatcaa ttccattctc ttgctgaaga
    82861 actggaagaa atcgaattga tggtggagat gttgcaggaa gaacctgatg cagccatgca
    82921 agaagaagca gaaacacgta tcaatgcgct agatgaaaaa atgaagacat atgaattatc
    82981 tatgttgtta gatggtcctt atgatcgaaa caacgccatc gttgaattgc atccaggggc
    83041 tggcggaacg gagtcccaag attggggcag tatgctttta cgtatgtata cacgctgggc
    83101 agagcagcat gggtatcaag tagagacact agattatcaa gcaggtgatg aagcaggaat
    83161 caagagtgtg accctactga tcaaaggaca caacgcattt ggttatctga aatcagaaaa
    83221 aggtgttcat cgccttgtac gtatctcgcc ttttgactca gcgaaacgac gtcatacttc
    83281 tttttgttcg gtagatgtga tgccagagct tgatgaaacg atcgatatag aaatcaatcc
    83341 agatgatttg aaaatcgata cgtaccgagc aagtggtgca ggtggtcagc acatcaataa
    83401 aacagaatct gctgtacgga tcactcactt gcctacagga acagtagtag ctagtcaggc
    83461 acaacgttca caattgaaaa accgtgagca agcgatgggg atgttaaaag ctaagcttta
    83521 tcaattagaa gtggaaaaga aagaacaaga agcagctgca cttcgaggag aacaaaaaga
    83581 aatcggctgg ggttcacaga tccgttctta tgttttccat ccatattcta tggtaaaaga
    83641 ccatcggaca aacgtagaga caggaaatgt ccaagcagtt atggacggtg accttgattt
    83701 atttattgac ggctatttaa aaatgcatct acaataagaa cccattgtta aattgaaata
    83761 aaattgtaag attttgcaag catgttgaaa cattgccatg ctataatagc taaagactga
    83821 aaaagatatg gagagaacgc catgattgaa atgaaggatg taatgaagaa gtactcaaat
    83881 ggtacgaccg ctatccgcaa tctctcaatt gtcatcgaac aaggagagtt tgtctatgtg
    83941 gttggtccgt ctggagccgg taaatctaca ttcatcaaat tgatgtatcg agaagaaaaa
    84001 gcttcaaaag gaactttgaa cgtcgcaggt catgatctaa tagcaatcaa aaaccgcgaa
    84061 gttccttatc tacgcagaga aatcggcgtg gtgttccaag actataaatt attaccaaga
    84121 aaaacagtat atgaaaatgt tgcgtacgct atgcaagtta tcggcagaaa acctcgggat
    84181 atcaaaaaac gagtaatgga agtgctggac cttgttggtt tgaaacacaa agttcgagtc
    84241 tttcctagcg aattatccgg tggggaacag caacgtgtct ctattgctcg ggcaatagtg
    84301 aatacgccta aagtacttat cgcggatgaa ccgacaggaa atctggatcc agaaaactca
    84361 tgggaaatca tgaaattatt agatcggatc aatgcccaag gaactactgt cgtgatggct
    84421 acacataaca gtacgatcgt aaatacgatt cggcaccgag taattgctat cgaaaacggc
    84481 cgcattattc gagatcaagc ggaaggggaa tatggatacg atgattagaa cctttttccg
    84541 ccatttatta gaaagtatca agagtttgaa acgtaacggc tggatgacag ttgcttcagt
    84601 cagtgcggta acgatcacat tgactttagt cggtgtattc atggcagtta tcatgaacgc
    84661 aactaaatta gctcaagata tagaaggaaa cgttgatgtc tctgtattcg tagatatcgg
    84721 tacaaaagac gaagagatga aaaagctaga aaaagaattg aatgacttag atcatgttaa
    84781 aaaagttgaa ttttcaagca aagaacagga attgaaaaaa atccaaaacg aaatgggtga
    84841 ttcctggaaa ttgtttgaag gtgacaataa cccgttatat gatgtgtatg tagtaagtgc
    84901 tactgatcct tcttatacaa aacaagtagc agaagaagca gcagatttga agaatgtttc
    84961 tcgttctgat tacggtggag cttcctcaga tcggattttc caaatcgctg gtgcagttcg
    85021 gacatgggga ttagttgcag cggcattgct gctgttcgta gcgatgtttc tcatttcgaa
    85081 cacgattcgg atcacgattt tgtctagaca gcgtgaaatt caaatcatgc gtttagtcgg
    85141 tgcaaaaaat ggatatattc gctggccgtt tttccttgaa ggtggctgga tcggtctgat
    85201 cggtgcgatt cttccgattt tgatcatcac atttggttat gcatggtttt tccaattgat
    85261 caatccatca ttattacgtt cccattattc attgattcat ccacaaaata tcgtttggaa
    85321 aatcaatctt ttaatggtcg gcattggtgt gatcattggt tcacttggct cgatcatttc
    85381 tatgagacgt ttcttgaaat tctaatacca caatataaat aaaatgagaa agttggacag
    85441 tttcgttcca gctttctttt tttattggct aggagaatag aaggaagcgg cttttttccc
    85501 tttactttaa aaaacaactt gggtattctt aagttggtag aagaagaggt gaagccgtga
    85561 aaattatcgt tgacaatttt tttacgatcc ttttgattat gaatattttg ctttccttta
    85621 tcatcgtttt tcgagaaaga aaggaaactg ctcaaacatg ggcatgggtg ctcgttttga
    85681 tgttcattcc agttgtagga tttattttat atattttttt aggaagaggg atttccaaag
    85741 agaaaatctt tgatttgaag atccaaggga aaatcggtaa gaacctggaa attgaagaag
    85801 acaaacaggc attgatgcga gggctttatc ctcatccgcc tactggacaa gtagatgtga
    85861 aacaattgat ctatatgctc acggtatttg aaagtacgct ctatacgact aaaaatgaaa
    85921 tcactttatt tacagatggt cgtgaaaaat tcgatgcgct gattgaagat atcaagcagg
    85981 cagaagacca tatccacttc cagtattata tttatcgcag tgatgcatta ggtgaagaag
    86041 ttcgagatgc attgacagag gcggcaagac gaggggtaaa agtcagagtc cttcttgatg
    86101 catggggttc cacacaagtt tcttccagct tttttcagaa tttgaaaaaa gcaggcggag
    86161 aagtcgcatt tttctttcct ctatttgttc cgtatattaa tcctcggatc aattatcgca
    86221 atcatcgtaa aatcgtagtt attgatggga aaatcggata tacaggtggg ttcaatgttg
    86281 gaaatgaata tctaggattg gtaaagaaat ttggttattg gcgagacaat catttgcgta
    86341 tttacggaga agcggtgtat accttgcaaa accgtttttt gatggactgg aattctcagc
    86401 atacaaaaga agtaggctat tctcccaaat tttttccgtc cattcactct actggtgata
    86461 tagctgttca aatcgtgaca agcggaccag ataccgaaca tgaacaaatc aaaatgactt
    86521 atttgaaaat gatttcgtta gccaaacggg agatattgat ccaaacgcct tattacatac
    86581 cggatggatc gattcatgaa gcactgaagt tggctcttct ttcaggcgta aaagttcata
    86641 tccaaatacc taacaaacca gatcatcttc tcgtttactg ggcaacgtat tctttcgctg
    86701 cagagctaat cgagtatgga gcaaggatcg aaacatatga gaatggattt attcatgcaa
    86761 agacgatgat tatcgatggt ggcattgttt cagttggctc agcaaatatc gatgttcgtt
    86821 catttcgctt ggactttgag gtcaatacac tggtttatga tgaacgaatg gcttcacgtg
    86881 taagaaaagc tttttttgaa gactcgaaaa tttctacgca tctcacaaaa gaaatgtatg
    86941 aaaaccgagg aataatcatc aagatgaaag aaggattagc aagattgatt tcgccgctcc
    87001 tttaaaacat aaaaaggaca tgagaaccat caacagatgg agatctcgtg tccttttcta
    87061 acggggccat ttctgagagt acgtcagaaa tggagaaagc gtctcgcatg agcgaaatta
    87121 actttggggt atctcttgtt ttttggggaa agcaagaaat aagctaatat atgctattaa
    87181 aagagacaca tttcaaagcc agtatagcat agaaactttt aatgagatag ttttttttac
    87241 aattatgaga atttattttg ttatttaatg attttgattc gttttcatca agtaatgaaa
    87301 atgataaaat aaacatactt taggattaaa ggagatttct aatgaaaaaa cttaaattat
    87361 tcttaccaat aataggatta gctattcttt tatcaggctg ttcaaagtgg attgatcgag
    87421 gagaatccat tacggctgtt ggctcttctg ctttacagcc tttagtagaa acagttgctg
    87481 aaacttacca gacagaaaat cctggaaaat tcatcaatgt acaagggggc ggaagcggaa
    87541 ctggtttgtc tcaagtacag tcaggagcag tcgacatcgg aaactctgat ttgtttgcgg
    87601 aagaaaaatc ggggatcgat gcctcagcat tagtcgatca tcgagtagca gttgttggga
    87661 tcactcctat tgtgaacaag gatattggcg taaaagacat cagtatggaa aacctgaaaa
    87721 aactatttac aggcgagatc aaaaactgga gtgaagtcgg tggaaaagat cagccagtag
    87781 ttatattgaa ccgcgcttca ggaagcggaa cccgtagcac gtttgaaaaa tgggtattgg
    87841 acggagaaac agctgttcag gcacaagaac aagattcaag cggaatggtg cgccagatcg
    87901 ttgccgacac acccggtgca atcagctatg ttgctttttc ttatgtttcc gatgatgtag
    87961 atacgttgaa tgttaacggt gtagaaccga cagatgaaaa tgtgacaacg aacaaatgga
    88021 cgatttgggc atatgagcat atgtacacaa gagatcatcc aaaaaaactg acaaaagaat
    88081 ttttagacta tatcttatct gatgaagtac aagataacat cgttggagaa ctaggttata
    88141 tccctgtttc tcatatgaaa gtcgaacgtg attggcaagg aaatatcgtt aaagagtaat
    88201 ctttacacaa aatttacaaa cttagctaaa cttttacatg ttattaaaac caaattgatg
    88261 ttcaatttgt acactgagtg agtatgttaa acctgattaa gggggagtca tctgtggaag
    88321 atgtgaaaaa agtattatta acaaaatcaa aacgttcaaa aatggaacag cgtggaaaat
    88381 tcatcagttt tttatgtatc gcgctgatcg tgttggttgt attatctatt ttttattttg
    88441 tagctagtaa aggattggcc acctttttta ctgataagat caatgtattt gattttctgt
    88501 ttggtacaga ttggaatcca agccaaatcg gagcaaatgg gaaaccaatg gtaggggcat
    88561 tgcctatgat cacaggttcg tttattgtga cctttttatc tgctatcgtt gccacgccat
    88621 ttgccattgg tgcagcagta ttcatgacgg agatctctcc taaaaacgga acgaagatct
    88681 tacagccggt catcgagctg cttgtaggta ttccttctgt cgtttatggt tttatcggtt
    88741 tatcagttat cgtgcctttt gtcagaagta tttttggcgg gactgggttt ggtatcttag
    88801 ctggtacatt tgtgttgttc gttatgatct tgccgactgt cacaacgatg actgttgatg
    88861 cattaaaggc agtgccacgg cactatcggg aagcttcatt agcgcttggt gccacaagat
    88921 ggcaaacaat ctacaaagtc gtgctacgag cagccgtgcc cgggatttta acagcagtcg
    88981 tttttggtat ggctcgtgcg tttggtgaag ccttagctat ccaaatggtc atcggtaatg
    89041 cagcattgat gccaacaggt cttactactc ctgcttctac attgacgtcc atcttaacaa
    89101 tgggaatcgg aaatacaatc atgggaacag ttgaaaataa tgtgttatgg tcattagcgc
    89161 tgatcttgct attgatgtca ttattcttta atatcgtgat ccgtatgatt gggaagaaag
    89221 gagagctgaa ataatgaacg caaaacgctc agataaaatt gctacaggtg ttttatatat
    89281 agtttcgggg atcatcgtat tgattttagc agctttacta ctttatatct tagttcgggg
    89341 aataccgcac atttcatggt ccttcttgac cgaaccttcc aaagcctacc aagaaggcgg
    89401 tggaatcggg atccagctat ttaactcgat ttatttgctt ttgatcacga tgatcatcag
    89461 ttttcctatt tctttaggtg cgggtatcta tctttcagaa tatgctggaa aaaactggct
    89521 aacagatgtg attcgcacgt cgattgaaat cttgagctcg ttgccttctg tcgttgtcgg
    89581 tttattcggt ttcttggttt tcgttattca attccagtat ggtttctcga ttatttctgg
    89641 tgcattggct ttgactgtat tcaacttgcc tcttttgact agaacagttg aggagtcttt
    89701 acaagcggtc cattacacac aacgagaagc aggattggcc ttaggtttgt cacgctggga
    89761 aacagtgata aaagtggtgg ttccagaagc gacaccaggg attttgactg gtgtgatcct
    89821 aagttctgga agaatttttg gtgaagcagc tgcattgatc tatacggctg gacaaagtgc
    89881 acctgcgtta gattttacga actggaatcc attaagtgtt tcaagcccga tcagcatttt
    89941 ccgtcaagct gaaacattag ctgtccatat ttggaagatc aatacagaag gcacgatgcc
    90001 tgatggtgtt tctgtttcgg ctggcgcttc tgccgtgttg attattgctg ttttactgtt
    90061 caacttcggc gctcgtgcga ttggcaaacg attataccga aaaatgactt cagcctaagg
    90121 agaagaagca aaatgaaaaa atataactgg aatgaaacaa atgtcatcac catgccaaaa
    90181 gagaaagaag tagcactata tacggatgat ctacatgtct ggtatggcga caatgaagca
    90241 atcaaaggag tggatctgga atttgaaaaa aataagatca ctgcactgat tggtccttcc
    90301 ggctgcggaa aatctacgta tcttcgttcg ttgaatcgaa tgaatgatgg gatcgctaat
    90361 acgaaaatca ctgggaaaat catgtatcaa ggcgtagata ttaatgcgcc tcaagtggat
    90421 gtttatgaga tgcgcaaacg gattggcatg gtttttcaac gtcctaatcc gttcagcaag
    90481 tcgatttatg acaatattac atttgctttg aaacagcacg gcgaaaaaaa caaaaagaaa
    90541 ttagatgaaa tcgttgaaac aagcttgaaa caagctgcct tgtgggacca agtaaaagac
    90601 agcttggaca aaagtgcctt ggctttatct ggcgggcaac agcaacgttt atgtattgct
    90661 cgtgcgatcg cgatgaaacc tgatatcttg ctgctagacg agccggcaag tgctttggac
    90721 cctatttcga caggaacggt tgaagaaaca cttgtaaact tgaaagaaga ctatacgatc
    90781 atcatcgtga cgcataacat gcaacaagca gctcgtatca gcgactatac tgcctttttc
    90841 tatttaggaa aagtaatgga atatgacaaa actaacaaga tatttaccag accaaaaatt
    90901 caggcaaccg aagattatgt gtccggtcat tttggttaag acggaggcct caacatgaca
    90961 aaagagatta tttcatctaa agatcttcat ctgtattatg gaaagaaaga agcactaaaa
    91021 gggatcgatc taagcttcaa tcaaggggaa atcactgcga tgatcggtcc ttctggttgc
    91081 ggaaaatcca cttatctgcg ttctttgaac cggatgaatg acctgattcc gaatgtaacg
    91141 atcaccggaa gtgttttata taaagacaaa gacatctatg gtccaaaaac agatgttgtt
    91201 gaactaagaa aagaaatcgg catggtattc cagcagccaa acccatttcc tttttctatc
    91261 tatgaaaatg tcatctatgg attgaaatta aaaggggaaa aagataaaaa agtccttgat
    91321 caagtagttg aagaaagcct gaaggcagcg tctgtttggg atgatgtgaa agacaaattg
    91381 cataaaagtg ctttatcttt atccggtggg cagcagcagc gtgtatgtat cgcacgtgtt
    91441 ttggcagtta atccggaaat catcttattg gatgaaccaa caagtgcgct tgatcctgtt
    91501 tctactggga aaatcgaaag tatgctgtta gaattaagag agcggtatac gatgatcatc
    91561 gtgacccata atatgtctca agcttcacgt atttcagata agacggcatt ctttttagat
    91621 ggtcacttga tcgaatacaa tgatacgaag aagatattca tgaatccaga aaaacaagag
    91681 acagaagatt atatttcagg tcgatttgga taaggaggaa acggaatgct acgtacacaa
    91741 tttgaagaag aattgctgaa tctccataat cagttctacg aaatggggat gatggtgagc
    91801 agcgccgtgc acaagtcagt tcgtgcatac atcaaacacg ataaaatctt agcccaagaa
    91861 gttatcgaaa acgatataaa tatcaataac atggaaacac gcttggagaa gaaaagtttt
    91921 gaaatgatcg cattgcaaca gccagttaca actgatttgc gtatgatcat tacggtcatg
    91981 aaagctagct cggatttaga acgtatggcc gatcatgcgg tgtctgttgc taaatccacg
    92041 attcgcgtaa aagggcagac gagaataccg gaaatcgaaa aagagatctc cgatatgtcc
    92101 gattatgtga aaaaaatggt ggacaacgtc ctagttgctt atgtcaaaac agacgaaaaa
    92161 gacgcacgta cgatcgccaa tatggatcaa agagtcaatg actatttcaa tcgaatctat
    92221 aatgcaacaa tcaaaaatat gcaggaaaat cctgagacag tcatcagtgg aacagactac
    92281 ttgaatgttg ccagttatct agaacggatc ggagactatg tgacaaacat ctgtgaatgg
    92341 atcgtctact tggctacagg gaaaatcact gagttaaata cgaaccacaa tgagattttc
    92401 taaactgaag ctgtgattat gccgtttgtt taggaaaaga ggttgtgaaa tcagcggttg
    92461 tgaaaaagct gttctgcatc aagtaataag aacagtcaaa caaaaaatag ctcctcatat
    92521 ttttcgtttg gctggactta ttaccgcaga tgcaagcttt tgaacaccgt ttattcggga
    92581 aagggtttgt gacaaaacat gtcacaaacc ctttt
//
LOCUS       DACBZK010000004        70838 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.004, whole genome shotgun sequence.
ACCESSION   DACBZK010000004 DACBZK010000000
VERSION     DACBZK010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 70838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70838
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.004"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            476..1339
                     /locus_tag="IVD66_000331"
     CDS             476..1339
                     /locus_tag="IVD66_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP6144580.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="IVD66_000332"
     CDS             complement(1468..3090)
                     /locus_tag="IVD66_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6144581.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="IVD66_000333"
     CDS             3339..3860
                     /locus_tag="IVD66_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144582.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="IVD66_000334"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="IVD66_000334"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HAP6144583.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="IVD66_000335"
     CDS             5941..6759
                     /locus_tag="IVD66_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005232914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HAP6144584.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="IVD66_000336"
     CDS             complement(6862..7059)
                     /locus_tag="IVD66_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144585.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="IVD66_000337"
     CDS             7228..7806
                     /locus_tag="IVD66_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAP6144586.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            complement(8851..9354)
                     /locus_tag="IVD66_000338"
     CDS             complement(8851..9354)
                     /locus_tag="IVD66_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAP6144587.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9713..10738
                     /locus_tag="IVD66_000339"
     CDS             9713..10738
                     /locus_tag="IVD66_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP6144588.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11085..11963
                     /locus_tag="IVD66_000340"
     CDS             11085..11963
                     /locus_tag="IVD66_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144589.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12439..12555
                     /locus_tag="IVD66_000341"
     CDS             12439..12555
                     /locus_tag="IVD66_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAP6144590.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13483..13821
                     /locus_tag="IVD66_000342"
     CDS             13483..13821
                     /locus_tag="IVD66_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144591.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13915..14145
                     /locus_tag="IVD66_000343"
     CDS             13915..14145
                     /locus_tag="IVD66_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144592.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14545..14916
                     /locus_tag="IVD66_000344"
     CDS             14545..14916
                     /locus_tag="IVD66_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAP6144593.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(15190..15882)
                     /locus_tag="IVD66_000345"
     CDS             complement(15190..15882)
                     /locus_tag="IVD66_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP6144594.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15885..16670)
                     /locus_tag="IVD66_000346"
     CDS             complement(15885..16670)
                     /locus_tag="IVD66_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP6144595.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16907..18307
                     /gene="lacG"
                     /locus_tag="IVD66_000347"
     CDS             16907..18307
                     /gene="lacG"
                     /locus_tag="IVD66_000347"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAP6144596.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            18332..18649
                     /locus_tag="IVD66_000348"
     CDS             18332..18649
                     /locus_tag="IVD66_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP6144597.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18662..20335
                     /locus_tag="IVD66_000349"
     CDS             18662..20335
                     /locus_tag="IVD66_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6144598.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            20349..21980
                     /locus_tag="IVD66_000350"
     CDS             20349..21980
                     /locus_tag="IVD66_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-1,4-beta-galactosidase"
                     /protein_id="HAP6144599.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            22852..24042
                     /locus_tag="IVD66_000351"
     CDS             22852..24042
                     /locus_tag="IVD66_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HAP6144600.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            24176..26365
                     /locus_tag="IVD66_000352"
     CDS             24176..26365
                     /locus_tag="IVD66_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6144601.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            26362..28155
                     /locus_tag="IVD66_000353"
     CDS             26362..28155
                     /locus_tag="IVD66_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAP6144602.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            28355..28669
                     /locus_tag="IVD66_000354"
     CDS             28355..28669
                     /locus_tag="IVD66_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018705633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP6144603.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            28690..29067
                     /locus_tag="IVD66_000355"
     CDS             28690..29067
                     /locus_tag="IVD66_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP6144604.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            29077..29850
                     /locus_tag="IVD66_000356"
     CDS             29077..29850
                     /locus_tag="IVD66_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144605.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            29872..31275
                     /locus_tag="IVD66_000357"
     CDS             29872..31275
                     /locus_tag="IVD66_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAP6144606.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            31457..32641
                     /locus_tag="IVD66_000358"
     CDS             31457..32641
                     /locus_tag="IVD66_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP6144607.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            32638..32928
                     /locus_tag="IVD66_000359"
     CDS             32638..32928
                     /locus_tag="IVD66_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144608.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            32925..33146
                     /locus_tag="IVD66_000360"
     CDS             32925..33146
                     /locus_tag="IVD66_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144609.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            33188..33967
                     /locus_tag="IVD66_000361"
     CDS             33188..33967
                     /locus_tag="IVD66_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HAP6144610.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            34034..34528
                     /locus_tag="IVD66_000362"
     CDS             34034..34528
                     /locus_tag="IVD66_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAP6144611.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            34584..35222
                     /locus_tag="IVD66_000363"
     CDS             34584..35222
                     /locus_tag="IVD66_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144612.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            35294..35689
                     /locus_tag="IVD66_000364"
     CDS             35294..35689
                     /locus_tag="IVD66_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP6144613.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            35673..38126
                     /locus_tag="IVD66_000365"
     CDS             35673..38126
                     /locus_tag="IVD66_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP6144614.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            38123..40150
                     /locus_tag="IVD66_000366"
     CDS             38123..40150
                     /locus_tag="IVD66_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144615.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            40147..41169
                     /locus_tag="IVD66_000367"
     CDS             40147..41169
                     /locus_tag="IVD66_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAP6144616.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDGETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            41186..42115
                     /locus_tag="IVD66_000368"
     CDS             41186..42115
                     /locus_tag="IVD66_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP6144617.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            42360..42476
                     /locus_tag="IVD66_000369"
     CDS             42360..42476
                     /locus_tag="IVD66_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HAP6144618.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            42492..44411
                     /gene="tet(M)"
                     /locus_tag="IVD66_000370"
     CDS             42492..44411
                     /gene="tet(M)"
                     /locus_tag="IVD66_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HAP6144619.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIV
                     NTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRL
                     NSRIDKVRYMFNKIT"
     gene            44509..44697
                     /locus_tag="IVD66_000371"
     CDS             44509..44697
                     /locus_tag="IVD66_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP6144620.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(44755..45108)
                     /locus_tag="IVD66_000372"
     CDS             complement(44755..45108)
                     /locus_tag="IVD66_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6144621.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            45639..46061
                     /locus_tag="IVD66_000373"
     CDS             45639..46061
                     /locus_tag="IVD66_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP6144622.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            46058..46288
                     /locus_tag="IVD66_000374"
     CDS             46058..46288
                     /locus_tag="IVD66_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6144623.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            46786..46986
                     /locus_tag="IVD66_000375"
     CDS             46786..46986
                     /locus_tag="IVD66_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP6144624.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            47013..48206
                     /locus_tag="IVD66_000376"
     CDS             47013..48206
                     /locus_tag="IVD66_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6144625.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(48274..49839)
                     /gene="guaA"
                     /locus_tag="IVD66_000377"
     CDS             complement(48274..49839)
                     /gene="guaA"
                     /locus_tag="IVD66_000377"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAP6144626.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(49898..50821)
                     /locus_tag="IVD66_000378"
     CDS             complement(49898..50821)
                     /locus_tag="IVD66_000378"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAP6144627.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            51017..51622
                     /locus_tag="IVD66_000379"
     CDS             51017..51622
                     /locus_tag="IVD66_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP6144628.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            51930..52946
                     /locus_tag="IVD66_000380"
     CDS             51930..52946
                     /locus_tag="IVD66_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6144629.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            53087..54388
                     /locus_tag="IVD66_000381"
     CDS             53087..54388
                     /locus_tag="IVD66_000381"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HAP6144630.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            54434..55096
                     /gene="deoC"
                     /locus_tag="IVD66_000382"
     CDS             54434..55096
                     /gene="deoC"
                     /locus_tag="IVD66_000382"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HAP6144631.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            55117..55515
                     /locus_tag="IVD66_000383"
     CDS             55117..55515
                     /locus_tag="IVD66_000383"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HAP6144632.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            55581..56663
                     /locus_tag="IVD66_000384"
     CDS             55581..56663
                     /locus_tag="IVD66_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6144633.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            56875..58437
                     /locus_tag="IVD66_000385"
     CDS             56875..58437
                     /locus_tag="IVD66_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6144634.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            58430..59563
                     /locus_tag="IVD66_000386"
     CDS             58430..59563
                     /locus_tag="IVD66_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6144635.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            59563..60519
                     /locus_tag="IVD66_000387"
     CDS             59563..60519
                     /locus_tag="IVD66_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6144636.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            60618..61784
                     /gene="deoB"
                     /locus_tag="IVD66_000388"
     CDS             60618..61784
                     /gene="deoB"
                     /locus_tag="IVD66_000388"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAP6144637.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            61808..62626
                     /locus_tag="IVD66_000389"
     CDS             61808..62626
                     /locus_tag="IVD66_000389"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAP6144638.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            62643..63350
                     /gene="deoD"
                     /locus_tag="IVD66_000390"
     CDS             62643..63350
                     /gene="deoD"
                     /locus_tag="IVD66_000390"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAP6144639.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(63648..64334)
                     /gene="gpmA"
                     /locus_tag="IVD66_000391"
     CDS             complement(63648..64334)
                     /gene="gpmA"
                     /locus_tag="IVD66_000391"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAP6144640.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(64506..65087)
                     /locus_tag="IVD66_000392"
     CDS             complement(64506..65087)
                     /locus_tag="IVD66_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6144641.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(65220..65903)
                     /gene="rpiA"
                     /locus_tag="IVD66_000393"
     CDS             complement(65220..65903)
                     /gene="rpiA"
                     /locus_tag="IVD66_000393"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HAP6144642.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            66222..66635
                     /gene="rpsL"
                     /locus_tag="IVD66_000394"
     CDS             66222..66635
                     /gene="rpsL"
                     /locus_tag="IVD66_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007085295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HAP6144643.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            66719..67189
                     /gene="rpsG"
                     /locus_tag="IVD66_000395"
     CDS             66719..67189
                     /gene="rpsG"
                     /locus_tag="IVD66_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HAP6144644.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            67283..69370
                     /gene="fusA"
                     /locus_tag="IVD66_000396"
     CDS             67283..69370
                     /gene="fusA"
                     /locus_tag="IVD66_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAP6144645.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            69542..70729
                     /gene="tuf"
                     /locus_tag="IVD66_000397"
     CDS             69542..70729
                     /gene="tuf"
                     /locus_tag="IVD66_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAP6144646.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
BASE COUNT        22883 a        12228 c        14387 g        21340 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacgt cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacgctt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc
     8521 atagaaaata taaagtaatt acttataaaa caagcttttt atagaaaaat aatatacctg
     8581 agtagggtat aaattaagac ggaattcctt tctagattga gatattgact aggaagaatg
     8641 ttaagatttt aagcctttaa gctaaaaaaa aacccttttt gttaaataag gggaatatag
     8701 cctgtcagtt tcaaactgca agtcgtcctg ctgcaataat atagtagatt agagatgaaa
     8761 atagattttt ttaaaccaat gactgaataa aaagaccgtc atagatacac attggaatgt
     8821 gtctattacg gtcttttttt acgaacgatt ttattgaaga cggacagttc gggtcaaaaa
     8881 taaaaaagct acgatcagaa ataagaataa aatgtatccc aaaataatgg ctagacggtc
     8941 taacttattt gtcgatagat gtttgtttag aagttgatag gcccataaac ctatcagtcc
     9001 tcctgttgta ttagttatca aatcagtgat gtccgctacg ccaataccga ataggaattg
     9061 aatcaattct gccaagaagc ttacaaggaa aataatccct aattttttag aaaaagaaag
     9121 tctcttgaaa ttgacattca aaagcacccc aaaaggaaaa aagacaatca agttataagt
     9181 ggtctcacgt aataccgtcg tattttcaaa agaaaaagta gaaaaaggga cgagattgac
     9241 attgctgtaa gaataagtga gaaattgtgg aagattaaat gatagcttga ataaaatcaa
     9301 ccataataga aagaataaat aaatccctaa taaaaatttt gatacatacc gcatagacat
     9361 ctcctccatt taaaaagtat accatcgaaa accgctgaaa aatcataaaa aagtatgaag
     9421 tttaaggacc aacgtagtta tcgtacgaaa attagaagct tttttttgtt gggaatccgg
     9481 tttctttaac aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca
     9541 aaacgactcg gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac
     9601 taagtttatg aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg
     9661 gcatttcatc ttggttcagc tttttttcca attactagga aggagggata gattgttcaa
     9721 gacttatttt cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct
     9781 acttatcttt attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt
     9841 ttcatcatta gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct
     9901 gaaacgtatg tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc
     9961 gacttatgtt ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt
    10021 cgtgttgcga ttattccata tttctaaacc aggtggcttg ttttttgcga tgctttctgc
    10081 catgggaacg agcatgcagc tgccaatcgc tcaattaccg atcgtctcac tttatttttt
    10141 tatgggtgtc gtttttgccc tgattgcggc agtgattaca aaattactgg attcacggcc
    10201 tgagcagaca attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat
    10261 cattgattct gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt
    10321 gaatctgcat aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa
    10381 cttggatgcg atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg
    10441 tgtgtcggca ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac
    10501 ttttctatat ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt
    10561 tcttaatccg atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt
    10621 gatcgaatat cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg
    10681 ggtaatgacg gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa
    10741 ggacaaatat atgtgccaaa agaggttatg acaagatttt tgtcacaacc tctaattcaa
    10801 ggtgttcaaa agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa
    10861 ctttcaaaaa aattttatat ttattctatc aaaaaatttt atatttattc tatcaaaaaa
    10921 ttttgtttat gatggtaact gaataaactt tcctgagatg gtcaatgctt tccttgaaag
    10981 tcttacagat attctttctt catagaaagt ttaagtttta tagttagtgt acaataaaag
    11041 tatgtttata ccatatggtg tccggataat cagtcattta aacaatgagg ttcaaagata
    11101 tgaaaagggg aaatttgatg aagaaaataa gcaatgaaat ccaaattctg gcagaaactt
    11161 taactcttcc caaagtcgtt atagagcaaa tgattgtaca agcaaaaaac atccttgatg
    11221 aggtgtttga gcaatatagt catgaactaa tggatcctaa taaagcaaag gcgactgcaa
    11281 agaaaataga caaagtctat gaagaggaac cttttgcagc attagctatt tatctatatg
    11341 cagcttctca aagttggaaa aaaatttatc aaccattgaa gattccaaga actatctatt
    11401 tggcaacaat gaatgctttt actagattta ttcatgaaca tttccaagta acaggaagct
    11461 atcgctttga ccgtggtttt tggatttggc attacactag tggcttgatc tttcggattg
    11521 gtgaattgga gtacgaaatg acatattttc cgaaagggta cacggatcta agattagaag
    11581 gaaagcagtg cctttctctt catattcctt ccgatgcaga tttatctcag aataagataa
    11641 gagatagtta cgaaagtgcc attcgttttt ttgaacttta ttttcctgat taccattacc
    11701 aagtgatgta cacagatact tggttactat cacccaatct tactaaatgg ttgaaaaaag
    11761 agtcaaaaat ctgtcttttt gcagccgatt atcgattatt atcagttgat gaacaggacg
    11821 atagtggagt cccttggatc tttggacgag tagatgccca aatacatgat tatccagaaa
    11881 gtacgagttt acagcgacaa gcaaaagagc aattgcttgc aggcgagcac attggctctg
    11941 gcttaggtat tcttacttca taagtttagt acttcgaaat agtttaaaag agcgtgagac
    12001 aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg aagcagaagc
    12061 aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt cgtgaatttc
    12121 ttcttatttc ttggagttaa acgcttctgt cccagcctct tttttagtgt tctatcgaac
    12181 acacagtacg ttcaataggt aaactagcta taacaataga tattaaagtt aacggacaag
    12241 agggcctttt ttaggtagct aaaacgtaat aatgaaaatt tatttccaga gataggagtc
    12301 aatcagctag tctgatcgac tgttttaaca agttgacttt cattttaact tttgatacca
    12361 tttaaaacac aaatcgtaat tgtttcgatt tgtgtttttt agcatgacta caatcaaaga
    12421 agaaagtggg tcgtccatat ggaaaaaaca gatatctcaa gtgcataccg ccgcttgaaa
    12481 agcccaaata tcaaaacacg aaaacgtgcg ctgaagatca tcaaagatgt gaaacggaat
    12541 agtgggaaaa ggtaagaaga aggaaactta attaaaaaaa tagccgaaaa acgtttttcg
    12601 gctattttca ataatcggtt tttgtgtaag gtttccgaaa gaactgctgt tgattttcca
    12661 tttttaacat atgataaatt ggtagaatct ttcttttcaa attgatacca ttccctaatt
    12721 ccagttatat agttaactac agaaccacaa agcacgtacg tttataaaag tattatctgt
    12781 agttattttt caattccctt tcaacctctt attttgacca gtagtattga tcactttacc
    12841 ttttaacacc tttgttcgtt tttgaaacat ttttagtcaa gaatggaaac gtaactacat
    12901 aatcaaaggt tttgcgaaat atttcatgaa atatttcatg tagaagcgag caatacggtt
    12961 gcaaataacc attatcgttt aataagcagt tacgaaagct cccaatatct ctaacgttca
    13021 gctcactcca tttcttttct tcaaaaaaat cagtgattcg tatctctttc tatttgtcga
    13081 aaaagttaac tttaaaaagt aacgccgaaa aaatatgcaa aaaaataaaa aagcagttac
    13141 tattgctaga ataacatcaa ggaataataa gttttggttt tcagataata gtcgataagt
    13201 tgtgtattgg aattttagat acagtaataa agtatttttc atgaaatttt gtgagaatca
    13261 ctattacaag tatctttaat aaaattaatg gttaaggagg aacttaaagt agaatgtaaa
    13321 tgaatagttg tagtcagtcg attgtgatac tagactcaaa gttgcaggaa taagtttttc
    13381 aatttgtgat tggaagataa aaaatgaaaa agaagggctt ttttttatac tttgttgatt
    13441 gtagtgttta ttttccctct gtttagccaa gtaacatttt ctatgactca accagtttca
    13501 agtgaggaac atgataacct ttttcgtgct acagaagagt ttaagaaata tcaggaaaat
    13561 attgttccgg agactccatt agctagtgag ccaattactg atattgatgg aaaccaaata
    13621 ggatggtata tacagtacga agttatggtg gtaaataatg actcaatagt aaaaaataca
    13681 gtaggcttag agctaacacc gattgaaaag gtgagttcat tgttaacgta tatttatact
    13741 gatgaaagtg acgagactga gatcatttta acggattact caaaaattgc tactgataaa
    13801 aagtatatat tgtggatgta gacactagtg aaatacttta tgatatagaa attgatgaaa
    13861 atttactaga tgtagcacaa gaaatcgatc atcaaaagca ggaagctatt cgatatgctg
    13921 gtagaaaagg gaaaagaaaa tatttattac gtgaatgtag caaaagttag agaagatgaa
    13981 aatgagtgga aagaattcaa gagtcgctac tcaattaact cgactccgac atttacagtt
    14041 tacagagaag gatcgataga aaaaactgtt ttttggacta aagaaagtgg aatgtcttta
    14101 gctgaagtag aagagttttt ggattatgtt agtatgcaac agtaagggag ttcttattat
    14161 gaaaaatttt gacacatatt atgttattgt tttttcgata tctttgctgt taatattact
    14221 aactttaatg cagtataaag agtatccaga gtattttatt ttaacttttg tatatttagt
    14281 aagtagctac acacttctat ataaattcag aagttcttct agagtttcta aagtttgttt
    14341 cttaattagc ttattgattc tataatattt ttgatttata taggaaatta aaaatattat
    14401 agaatcaaca ctcagagaac gggttggttt ttaatagatt taataagtac tgataatgaa
    14461 atttctcctg gttgggaaaa cgaagttggt taccctgtag aagaattttt tcaagattac
    14521 tttgcggagt atgccgatag gataatgaga gattacgtaa cagataaaac tcaagaagtc
    14581 atcaatcaat cccagtcatt aaatgaatta tctgataagg cgaaagaaga agcagttgcc
    14641 attatttctt cagggattag tgactatatt gatatgagtg gtgaaatcaa ttatggcgat
    14701 aaagacaaaa ttgtacgcat gataaaagct tttatcaaaa cttttgatgt gaaggcagat
    14761 cttaagttta atgatactta cctagtagga aaattaatta atatccttgg gacagagaaa
    14821 gatacggaaa cgtttatttc ctctttgtct atgttgttta cagataagca tttttcaact
    14881 cagcttggtg gagaggaact agtggaaatc ttttaaccat tacgcccagc attaataaaa
    14941 gtatatcaaa aaagtactcc tgatgatttt taagattggt ttgagaaata atgtgaaaac
    15001 actattttta atgttaatta tagatagaga tgaacgcgtc atatggttaa aagaatgaaa
    15061 aagtcaaaga tacactgcta tatttcacta aggatatagc agtgtatctt tcatgtcgtt
    15121 tcactggcag ttttttataa aaggaggtgt gcatttcagt tgcttttctt tggtagttag
    15181 ttgaatcgtt taagaattaa cggatgtggc agacaggtgc tctgtccaaa aaccagtaaa
    15241 atctttgatg gttccatctt tatttagctg tgcctgttca aatactgttt tgtttttacc
    15301 gaatggatca attgcaataa ttgttccgat ccccgcacgt ttggcagcaa gtaatcctga
    15361 gtaagcatct tcgataacaa gacaatcagc cggagctaag ctcagtttgt ctgccgcttt
    15421 aagaaaaata tccggttgcg gtttcccagg gaaagagccg tcgtcataga caatcttgtc
    15481 ccagtcaaac cagcgggcta aatcgaaaat atcaaaataa aaagcaacat tctctttgac
    15541 agtagccgtg gcaatcgtta atggaatctg ttggtcagtc agctggtcaa gagtcgcttc
    15601 aagccctttt gtcaactgaa gctcgttttc attttgcaag caaagcatac gataatagct
    15661 ttctttttct tctgacaata cggcgatctc agaggcggtc aaatgctctg aaatgaaatg
    15721 tttcaaaatc tccgtattcg tccgaccatg aatatttttt aaaatatcct cgtctgataa
    15781 accatctttt gtatgatcat gtatcatatg cagccaagca gcttcatgca gatgagagtc
    15841 caaaaacatt gttccgttga aatcaaatat aatccctttc atagttacgc tcctatagtg
    15901 gtattttcgg ttgaatcagc aatttgcaga tcgacatatt gtgcatagtg ctcttgaacc
    15961 tcccgcgaga tctggcgatc cgtaatgagc agatcgaaat catgcaaatt ataaaacaca
    16021 taaaaatcat ctcgattgaa ttttttatta tcaacgagta gatatttctt acgggaatta
    16081 tttagagcga tctgctgtgc ttctccttct tcggtactgt aagtagagat cgcttcgttg
    16141 tgaacgccat ttgaactgat aaatgctttt gtaaacttta gtcttcttaa attgtcgttg
    16201 gtgatcggtc cgacaaatgc gccggtattt ttccggaaat caccgccaat cagtagaatt
    16261 tctggtccat ctgcttgagc aagaatatca aaaactggat aattatttgt aatgatccga
    16321 attttcttgt tcagtaaatg cgtcgccaat agttcgattg ttgtacctgg tcctaagaaa
    16381 atcgtttctc cctcgtgaat caaggaggct gctgtggcag caatttcttt tttttcttga
    16441 atctgcagag tggctttttc agtgtgagaa agttcttgat ctaaagtgta ggaaagactt
    16501 tgagcccctc catggacacg cagcagcttg cccgattttt ctaattcatc taaatctctg
    16561 cgaacggtca tatcagaaac atctaattga ttgatgattt cattaacggt aaggattcct
    16621 tttttattga ccatttctac gatagtaagc aatctttctt ttttcaacat tgtcttcacc
    16681 tctaatttaa ggataatcta tcatataaac ggacaacagt caatctaatt cgaacaaaag
    16741 taaacattta gggtggtttt tatgtttgtt acaatagatt ttattgctgt tttctggttt
    16801 ttatgattat ttgtgtttgt ttttgttgac aaatgttttg gatgcgttta caatgcaatc
    16861 agttagaaag agcgaaaact gattatagat ttgaggagag atgtacatgc ttaaattacc
    16921 agaagatttt atttttggcg gagccacagc agcctatcag gttgaaggag ccactaagga
    16981 aggtggcaaa ggcgctgttg cttgggatga ctttttagag gaacaagggc gattcagtcc
    17041 cgatccggca agtgattttt atcatcaata tgcaaaggac attgaattgt gtgaacgttt
    17101 tggtgtaaat ggtctaagat tatccattgc ttggagccgc atttttcctg atggagctgg
    17161 gaaaccaaat ccagaaggaa tcgcttttta tcatcgtgtg ttcgaagaat gtaagaaaag
    17221 aaacgtaacg ccgtttgtga cgttgcatca ttttgatacc cctaaacgtt tgtttgacca
    17281 tggagatttt ttgaatcgag aaacaataga agcatttgtt tcctatgcca ttttttgttt
    17341 tcatgaattc aaagaagtca aggtgtggag tacctttaat gaaatctatc cagttgcaac
    17401 caatcaatat ttgttaggtg ttttcccacc aggaatcaaa tatgatttta caaagatcgt
    17461 cgcctgtctt cataatatga tggttgctca tgcccgtgta gtgaactatt tcaaagaaaa
    17521 cgaacttccg ggtgaaattg gtgtagttca ctcattagag acgaaatatg cggcaacaga
    17581 cgcgccggaa gataagcatg ctgccttttt agacgatgca ttgtcgatcc gtttcttatt
    17641 agatgctacc tatttaggct attattcaac tgaaaccttg actgctcttg atgagatatg
    17701 tgaagcaaat caggccagct atcattttcc tgaagaagat ttcgttgaat tgaaaaaagc
    17761 atccacgcgt aatgactact tagggatcaa tcactaccaa tgccattttg tcaaagctta
    17821 cgatggagaa aatgcaatcc atcataacgg tacgggtgaa aaagggacct ctgtttataa
    17881 agtgaaggga atcggagaac gtatttataa agaaggaatt cctcgaactg attgggactg
    17941 gctgatttat ccagaaggtc tatatgactt gttgctgcga attaaaagcg attacccaca
    18001 ttacaacaaa atctatatca ctgagaacgg gatggggtat aaagatcagt ttgaagatgg
    18061 cattattatg gatcagccga gaatcgacta tttgagagtc tatttggaat ccttaagcaa
    18121 ggcgataaca gccggggtaa atgtgaaggg gtattttttg tggtcgctta tggatctttt
    18181 ctcatggaca aatgggtata acaaaaggta tggcttgttt tatgttgatt ttgaaaccca
    18241 gaagcgttac ccaaaagaat cagcttactg gtacaagttg gtcagtgaaa ccaaaacgat
    18301 tatttaataa gtgataatgg aggaagaaaa gatgaataaa gaggaattac aaatgcttgg
    18361 ttttgagatc gttgcatatt caggcgacgc tcgcagtaca ttattgaaat tattgaaaga
    18421 agtaagacaa ggaaactttg aacatgttga ttcggcgttg aaagaagccg acgaaaattt
    18481 aacccttgca cataattcgc aaacaaaaat tttagcggaa gaagcatctg ggaaagagat
    18541 ggagatggga ttcattttta tccatgggca ggatcattta atgaccactt tattgctgag
    18601 agatctgatt caagacttta ttgtactgta cagacagaat caaggatagg agaagaacgc
    18661 tatggatgga atcattaaac aaatcgaaaa agggaaacca ttttttgaaa aaatctcacg
    18721 taatagttat ttaggagccg ttcgtgacgg atttttaaca gcgatgccag ctattttatt
    18781 ttcaagcatt ttcattttga ttgctgcggt tcctgagatt tttggttacc aatggcctga
    18841 atctgtctcc acatggctat ggaaagtcta taattattcg atgggtgttg tagggttact
    18901 cgtttcagca accactgctc gctgcttggc tgattcgatg aatcgtcgct taccgaaaaa
    18961 caaagtaatc aacaccacct ctgtgatgct ggcctctgtg gtaagtttcc tgttgttaag
    19021 cgtctctccg attgaaggtg gattttcaac ggaatatatg gggacaaagg gactactggc
    19081 ttcctttgtc gctgcatttt taacagttaa tttatataag ttttgtgtgc tgaaagatat
    19141 taccattaaa atgcctaaag aagttcctgg aacgatttcg caaaccttcc gagatatttt
    19201 tcctttctct ttttcagtat ttgcggccgt tttaattgat ttaggcattc gacaaatctt
    19261 ccaaatctca tttgcagaag caatcattac ggtgctgcag ccgctattta cagcagctga
    19321 cgggtactta ggaatcgcta ttatctgggg agcgatggcg ctgttttggt ttgtcggtgt
    19381 tcatggaccg tcgatcgtgg agccggcaat tgcggcaatt atctatgcca atgtggaaac
    19441 caatctgcaa ttgttcaatt ccggtgaaca agcttctaaa gtactgacgg tgggtttagg
    19501 gaattttgta ggaactatgg gaggaactgg ggcaacattg gttgttcctt ttatcttcct
    19561 actctttgct aagtctaagc agttgaaggc agttgggaaa gcttccttta ttccagtaag
    19621 tttcgctgtc aacgaaccat tgctatttgc ggcacccatg attttgaacc cttatttttt
    19681 tattccattt ttgttaacac ctgttgtaaa cgtttgcctg ttcaagtttt ttgtcgatgt
    19741 attgggcatg aacagcttta tgtacgtttt gccttgggca actccagcac cgatcggttt
    19801 ggttctagga acgggcatgg gtatcttagc ttttgttcta gcagcggttc taatcgtcgt
    19861 tgacttcctg atctatctac cattttgcaa agcatacgat gctgtcttag tagagaaaga
    19921 agcacaaaaa gcagaggtga tcgcaaccga ggaaggtgct tctgccgatg tacgtgagga
    19981 agtacctgtg gcagcgagtc aagttatcag cgatgcaaat aaagaaatca atgtgttggt
    20041 actttgtgct ggcgcaggga caagtgcgat gttagctaat gctttaaaaa aaggtgcatc
    20101 tgaatcgaaa gcaccgatca gtgcaatggc gggtgcttat ggttctcatt acgaaatgct
    20161 gcaggatttt gatatggtgg tcttagcacc gcaagtcaat tcttactatg atgatatcaa
    20221 agaagacacc gatcgcttag gaatcaagct ggttgcgaca aaaggagcag aatatatcgg
    20281 attaacgaga gatcctgaaa aagctgttca gtttattctg aaccaatttc aataaaggag
    20341 gagccataat gaaaatggga atttggttgc gtaaagctgt tttatttgca gctgtgttag
    20401 gggctttggg ggctgtttca aaaactgttg aagcatctgc cagcgaattt attcgcggag
    20461 cagatatttc gatcctgtca gatatggaaa aatctggtgc aaaatattat gaagacgata
    20521 tttcaaaaga tgccttagag attttaaaaa ataatggtgt caactatgtt cgactgcgtt
    20581 tgtggcagga tccttataat agtaatggag aaagttatgg agcagggaca aatgatctgg
    20641 aaacgacgat tgaccttgca aaacgagcaa aaaatctggg acttaaggtg ctgctggatt
    20701 ttcactacag tgatttttgg gttgatcctg ggaaacagaa tcttcctaaa gcatggcaag
    20761 gtctgacctt tgaagaaatg aatacggcat tgtacgacta tacaaagaac gttctgtcgg
    20821 aaatgaagca gctggacgtt tatcctgata tggttcagat cggcaatgaa ctgaatagcg
    20881 gaatgctctg gccttatggc aagtcttggg gagaaggcgg gggagaattt gatcgattgg
    20941 ctgctttttt gaagtctggt atccaagctg ttcgagacac tcaacctaaa acaactccag
    21001 taatgctcca cttagctgat ggtggcgata caggagcatt tacttggtgg tttgatgaaa
    21061 tcacgagtcg aggtgtgtca tttgatttaa ttggagtgtc gtattatccg tattggcacg
    21121 gttcaatgaa tgaacttcaa accaatatga atgcgatcag ccaacggtat ggtaaagaag
    21181 tgatcgtagt tgaaacagct tatgggcata caacagcgaa tgccgatact atgccaaatg
    21241 cttttggtga agccgaagca gctgcggggg gatatgaacc aacaccgaca ggacaagcag
    21301 agtatttgct ggatcttgcc gatcggattc aggcagtacc gaataatcgc ggggcgggct
    21361 tcttctattg ggaacctctt tggtacaacg gaaatgtgag ttgggcaaca caagcaggta
    21421 tgaattatct cagtgttcaa tccactatgg gaaacgaatg ggacaaccaa gcgatgtttg
    21481 attttgctgg aaacgccttg ccaagcttgc gtgcgtttaa acaagcaggg gcgcaaataa
    21541 atctagttaa aaatgcaagt ttcgaaagcg atggaccaac gaccagtcct tccaattggc
    21601 aaacctggtt tcaacaagga accgctaagg gtacgatcaa aacggaagcg ggcacttttt
    21661 ttggggacta caaactaact ttttggcagg atcaagcata cgaggcatca gcttatcaaa
    21721 atgttagtgg cataagcaaa ggaacttaca cattgagtgc ctatgtaatg tctgggggag
    21781 agtttgatac taatcagtta tatatcaaaa attatggtgg agcggaacta aatactgcgg
    21841 ttgttaaaac aagtgaatgg acaaaaatta caatcaaaga cattccaatt acaacaggtg
    21901 tttgtgaaat tggggtttat agcaaggctt caggaaatgc ttggacgaac gttgattttg
    21961 tttcattggt gaaacaatag actgcggatc gtttcgattc aagatcggag gttcccttca
    22021 gccacatcgt tagcgtagaa ggcaggaatc gaacctgcac ctcgcctttg ccaaaaataa
    22081 ccagaaacga tttccagtca tttttaccaa aacgagtaaa gcaccagact tcatctacac
    22141 tttgtattat gctaaagaga gttcaacgat ttcgtaagaa gcaatgaaaa aattgcaaaa
    22201 agttgtgcag ataacataaa gtttgtttaa gaaagggtaa ccttagaatt ccgtcgtgaa
    22261 tatgatttga gcacttagat ggatagaaaa aagttctcgg aaaacagttc gtttttcgag
    22321 aacttctttt tatgataaga atgaaacaaa ttaacttata ttatagtctc ttttggtagg
    22381 gaaccatctt atttttaatg aaaatcaagc attttagcta ttgaagaatg ttgatttata
    22441 gggattcccc ctccatatta tgttggctct ttattcccac tctgttttca acgtaaagtg
    22501 tataaaacag aatgcgatac tatcaaggga gttaaaacaa tatacagaac agtaaaacac
    22561 tataaataaa aataaaagtg caataaaagt gcaatttttg cacctaatca tactctgttt
    22621 atatatgaaa actagattct gaatccaata tttggttaac gagaggcgtt cgaatttgaa
    22681 cgtcttttat atattacttt caaataaata tgaggtagaa tactatctat tttcttttta
    22741 acccaattgt tataatggag agtgtaaaat attttgtgta aatagaaaaa aggaagtccc
    22801 ttctgtagaa tagagttacc acaacacatt cacagaagag aggacttccc tatgaacgat
    22861 tttactacag aaattctaaa gactctagcg aacaaaggcg atttgaatga attattccgt
    22921 gtccatttgg agaaagcagt caatacgctt ctcaaaacgg agttaacggc tttcctagat
    22981 tacgaaaagt atgatcgcat tggttttaac acgggtaatt ctcgtaacgg ctcctatgac
    23041 cgtacggtca agaccgagta tggggaactt catctccaga ttccgcgcga ccgcaatggt
    23101 gagttcaagc aacagactgt tcctgcttat agacggacga atgacacgtt agaggagacc
    23161 gtcattcacc tcttccgaaa aggtattacc atgtcggaaa tcgcagactt gattgagaaa
    23221 atgtatgggc attactacac gccccaaacc atgtccaata taacaaaatc atttacagaa
    23281 gaggtaacgg cgtttaatgg gcgggagctt catgaccgtt atgctgctat ttatatggac
    23341 gcaacgtata ttccgttaaa gcggaaaacc gtcgccaagg aagctattca tatcgcagtt
    23401 ggcattcgcc cggacggatc aaaggaagta ttgagctatg cgattgcacc gactgaatcc
    23461 atcacgattt gggaggaaat tttattggac cttcaagagc gcggtttgaa aaatgtcctc
    23521 ctgttcatca cggatggctt aaaggggatg gtaggagcga ttagtcggtt ctatcccaaa
    23581 gctcgttttc aacattgttg tgtacacgtt tcccgtaata tcagtcataa agtgcgtgtc
    23641 gatgatcgta aggaagtctg tgatgatttt aaaatggtgt atcaagcctc atctaaagag
    23701 gtggcgttgg aagcacgtgg tacttttgcg gaaaaatgga aaaccagcta tccaaaagtg
    23761 gttgaatcga ttctttcgaa cgatcacttg ctcactttct atgatttccc cttggccata
    23821 cgcaagagta tttattctac gaacttgatt gaatccttta ataaacaaat caagaaatac
    23881 agccaccgca aggaacagtt ccaaaatgaa gagtcgatgg aacgtttctt agtctcgtct
    23941 tttgatactt acaaccaaaa attcctaggt cgcagtcata aaggtttcca acaggccgaa
    24001 ggcgagctcg aacaaatgct aagccaactg attgagaatt agaaacaatc tgcagtaggg
    24061 aagaatcatt tacacaaaat tattgacgct cccttataat gagaactttt actaacataa
    24121 tttatgataa acttactata taatcatatt aattaaatag ttaggagatc tgcttatgtt
    24181 tatatctact cttcaaattc gaaattttag aaattatgaa tccgaaatct ttcgattcga
    24241 taatgagaca aatactatta taggtgagaa tgattcaggg aaaaccaatg ctcttactgc
    24301 attgagaatc ttattagatg atagttatta ctatagtagt aaaacactaa aagaatcaga
    24361 tttttttcat ggaattcaaa atgggtggca agggcattgg attattatct ctgcgacatt
    24421 tgaaggaatc agcgaagaag aatttgacaa tgagatttgt gcttccattt ctttaaattc
    24481 tgaaagtcaa acaatcttag aagaattgat ttcaaatgca gataaaggtg taggtagtat
    24541 ttctctattt attagaccta acaaagctat tagaaagcaa ttatttgata tttccactga
    24601 attagactct catcaattta acgaatttag aaattctatt cgtctatccg actatgaatt
    24661 ttactacaca tctaaatcaa atctaaattt ctgtatcaat gaaaattatg ataaattggt
    24721 aggaagactc aatgacaata tagctagtaa tcctgaagaa gacgatgaag ctctgttggg
    24781 ctcaagaatt gacatgtcag atattttcaa gcatatttcg gttgtttatg ttgacgctct
    24841 tcgagatgtt cttagagaaa tgaaaaacaa tcgaaaccca gtcaaaagaa tcatggaaac
    24901 aattgaatca aaaatatcat cagataatgt tgagtcatta aaaacaatta tacagcaatt
    24961 aaatgagact attaccagtg ttcctgaaat taggaaaatt ggcgaaaata ttaatcggca
    25021 actaaatagc ataattggtt cagtgtattc tcctaatctt cttctttcct caactatgtc
    25081 agatgatatg ggttctttag caaaatttct ttcaatgaag ccagaacaaa atatcgactt
    25141 agacttacta gggttaggac atctaaatat gatttattta gctttgaaaa tagtcgaatt
    25201 tgaagcgtgt cgttcaagag aactacttaa tattatgttg attgaagaac cagaagctca
    25261 tattcatcat catattcaaa aaactctgtt cgaaggatta aatcttcaaa aaaactatac
    25321 tcagattctc atgaccacac attctgtaca tttagctgaa gtgtctgaaa tatctcggat
    25381 gaatgtatta aaatcgttta atggcaaatc tatcgttatg aatccagcaa ataatctgaa
    25441 ctcatttgct aaagaaaagt taaaaaagaa caatctaaat ctaataaacg cagtagagag
    25501 atatttagat gttaaaagaa atggattgct tttttctaaa ggtgttatct tagttgaagg
    25561 agatgctgaa gaaatactta ttcctcaaat agtaaaaaaa ttatttggta taaacttaga
    25621 cgaacttgga ataggtttga ttaatgttgg tagtacttcg tttgaatata tcgctagctt
    25681 gtttgacgat gatagaatac agagaaagtg tgctattgta actgatttag atgaacaggc
    25741 aatcccatca gaacatcgat tgtataaaag cactgcacaa gagaaaggtc aagcaagaaa
    25801 agaaaaatta tcctcccttt ttaatgaaaa caattgggtt aattgttttt atgctaatac
    25861 aacatttgaa attgagtttt tagatgtgaa taaagaaaat attctaactt atgtcagtcc
    25921 aattatagat gacgcattca aagataaaaa aacaataact gcttataaag aagaaataca
    25981 aagtgaacaa tatttagaaa gaaatttagc gatgttaaaa ctagccaatc atgttggtaa
    26041 ggggtggttt gcaattgagt taggtgaaaa aattgacttt ttaatcaaaa ttcctaagta
    26101 tattcttaat gctattgctt ttgcatgtca ggaaatagta gatctctcaa tttataaaaa
    26161 aattctactc catacaatcg acttgtacga ggaaactaca gaattgtcag ctttatcagc
    26221 tagtttaaaa acaagtgata cagctgattt gaatatagca ataatttctt tattagagta
    26281 ctttggtaaa gatgaggatg ttgtgtatct aatcaatcag atagaaaatt acacaaaaat
    26341 actttatgct gaggtttcaa aatgacaaat atcttcgaaa aaatcgtaaa tgatttaaat
    26401 ttagaacaaa aagatgttgt ggaaagtgaa gataaccttt atgtaaatgc atgtcctggg
    26461 agtgggaaaa caagggtact tacaaggaaa attgcttacc aagcaattaa acacgatgga
    26521 tcactaaaaa gaataattgc tatcacatac actaatagag ctgctgaaga aattaaggaa
    26581 cgcctaagtt tacttagtat agatgatgat attaatattt gggtggggac aatacatcag
    26641 ttttgtcttg aatttattat ttatcctttt aaaatgaatc tctcaagagt atcaaaagga
    26701 tttacaatta ttgatgatta tactcaaaga gcttacgtca gccaaattaa taatatgctg
    26761 aatttaaatc tcaaaacgta tgaactgaac aaaattgatt tgtcactttc tcatgatttt
    26821 aaaattaatg aagttcagta tactcaagtt tctgaaatgt atcacactat gttggaaaaa
    26881 aataaagaaa ttgattttga tatgatttta ctagtagcgt ataaaatttt aactgtaaac
    26941 agtaacgttg cacgtaatat tgctagtaat ataagggcga tttatgtgga tgaatttcaa
    27001 gatactagag aattacaata caatgtaata gctaaattac ttcaaaacaa ccctcaaatt
    27061 cagtcaatgt ttgttggaga tattgaccaa gcaatttatg gatcattaga tggtatagct
    27121 aaatcagttg aagaactaga aatgctaact agtcacactt ttcaatcaaa gacgctacat
    27181 ggctgttaca ggtctaatca gagattagta gacttctact ctaattttca gagttgtcct
    27241 tacgagattg aaagcagagg gaataataaa aacgaccgtg gttttataag ttatgattgc
    27301 aaagttacta aggaggattt acccaacata ataaaaaata taataaagga aaagattgaa
    27361 agcggcattc atgaaaaaga tatttgtgta cttgctcctc aacactatcc tctgttttca
    27421 ctgggtgagt atttaaagaa agaattaccg tattgcaatt ttgatgctat aaatatatca
    27481 ccaattaagg taaataatca tagtttattt ttcaagttag caattttgta ctttactgaa
    27541 tcaggtgaaa aggttcgaag aagaaagcta attgcaaacg atattttaat tatattaaaa
    27601 aatgaatttg gaatagaagt taaagattat tttattgact tagatttatt acagctaata
    27661 aacagtgtga aaagaatgta tagtggagac gacaacggtg ttgatttata caaatttgtt
    27721 accaaacata tatttgttaa tcttaatatt gacgagaaaa attacccgtc tatttttaag
    27781 cactatctat tttttattaa cgaagtagaa gatcggataa aaaataattc attatctagt
    27841 agtgtatcta gttttaagaa gatgtttaaa tctcgagatg gtatcacact tactacagca
    27901 cataaagtta aaggaaatga gtatgatact gttatcgcta ttaatcttct aaacgggaaa
    27961 attcctcatt ggaatgaaat ttttaatgtt tctgataaag gaattagttc agcgagaaaa
    28021 ctactatacg taatttgttc aagagcaaaa aataatttat ttcttttctc agaggtgggt
    28081 tattttacga gtaaaggaga cttgctttat cccactcaat tattagataa aatagaattt
    28141 gattataata tttaaaatac ctaggtagtc gttgttttaa atatagtagg aatcggacgc
    28201 tcagtacgga gcgtctattt ttttacccaa ttttgaaagg aagtgaactt atgaaaataa
    28261 aaaatcaaga atcaaaaggt cgctctcccc cctttaaaac catcacacaa ataagattca
    28321 ttcaaacata aaaacagaaa ggataggtaa aaatatggaa cttaaatatg tcattcccaa
    28381 tatggaaaaa acatttggac aattagaata tgctggtgaa gggaacattg aacaacgtcg
    28441 aataaatggc agaccaacca ttctctctcg tagttacaat ttatactcaa cgattcaacg
    28501 agcagatgat attgttgtca ttcttccctc cgaagctggc gagaaacatt ttgaatccga
    28561 cgaaaaagtc aaactcatca acccacatat taccgcagaa ggttataaaa ttggcaatcg
    28621 aggatttacc aattacatta tgcacgcaga cgatatggtg aaagcataag aaaggaaagg
    28681 tgaaaaaata tgagattagc agaaggtatt gtgattgaaa aagaccagac atttggcaca
    28741 ttgaaatttt ccgccttgcg tcgtgaggtt cgtatccaga atgaagatgg tacggtttcc
    28801 gaagaaatta aagaacgtac ctatgactta aaatcaaaag gacaaggacg catgatacaa
    28861 gtcagtatcc ccgcttctgt tcctttgaaa gaatttgact acaacgcaga agtggaatta
    28921 atcaatcctg tggcagatac cgtagcgacg gctacttttc gaggggcaga cgttgattgg
    28981 tacgtgaaag cagacgatct tgtattaaaa ggacagacaa aacctcatca gaaatataaa
    29041 aaagaagcgt ccgaaagtga aaaataggtg ttgcttatga caaacacacc attgattttg
    29101 aaagaaattc cgaaggatga agccatttct tttattcggc aataccatta ttcaaagata
    29161 ctccctagat tgtgtaaata ctttctaggg attttttcag aagaaaaatt attaggcgtt
    29221 gtggaattag gctggggtac gcaaccccta caaaccatac gcaaactctt tcccgacagt
    29281 tcccttcaaa ccacagatta tttagaaatt ggaaagatgt gttttcttcc agaaatgaat
    29341 caaaccaatt attttggcag tcaagctctt tcagctctaa ttaagtggtt gaaagaacat
    29401 acggactgtc attttttata tacactggca gatggaattg agggaaaatg tggctatgtc
    29461 tatcaagcgt ccaacttctt ttactgcggg tatttcaaga caagtgtcta tcgtgataag
    29521 cagtcatggg aaaagataca ccctcgaagt gctcgccttt tattagagga aaatgctcgc
    29581 tttgaacagg tagagaaaaa gcattggctt tcccaggcat tttgcgaata caaagggatt
    29641 gagaaaatca atggacgcat gtttcgctat ctctatccgt tgacaaaaga agcgaaaaaa
    29701 ctgttaggac acactctcta tcgacgtcat tattatccga aagaaaaaaa tttacgcttt
    29761 gaaaagcgaa tcgcttatca gaaatatgaa gccatttctc aaccaacttt tgataaacag
    29821 gctcgtatct acaatacaca attattttga taggtggaaa ggaggatttt tatgccattg
    29881 cttcatgaca gaggagagcg aatcaaagcc aacgataagc acttggtcta tcattttgta
    29941 ctaatttcat tgctggtagt ttttctagtc gtcctactcc cttttcattg gagagcgtta
    30001 caatcggtga actggcaagc agttcagtta gatacatttt tctatcaact tcatacgcca
    30061 tacttttgga gcagtattct cactgctctt tttgtatgcg gacttatcag ctggctttat
    30121 tatcactatc gtatagattc tataaaacag ttagagcacc gtcaaaagtt agctcgtatg
    30181 attttagaaa atcattggta tgaagccgaa gaaactcaat cagagggatt ctttaaagat
    30241 ttacccagca agaaaaccaa acaacgaatc cgccattttc ctaaaatata ttatcgaatg
    30301 aaagatggac taatccatat tcatgtagaa atcaccttag ggaaatatca agatcagctt
    30361 ttgcacctag aaaacaaact agaaacagga ttgtattgtg aattagtgga aaaaacgttg
    30421 aaagattctt atgtagagta tgtcctactt tatgatacta ttggcaatcg aattggcatt
    30481 gaagacgtgg tagctcaaga tggacgtgtc aaattgatgg aatcggtcta ttgggagttc
    30541 gattctctcc ctcacatgtt aattgctggg ggcactggta gtggaaaatc ctattttatt
    30601 ctcacattga ttgaatctct cctgcataca aatgcaaagc tttatattct tgaccctaaa
    30661 aatgctgatt tggcagactt aggggcggtc atgaataatg tctattaccg taaagaagat
    30721 atgttggcat gtatcaatca attttacgaa gatatgattg atcgcagtga aaccatgaaa
    30781 caacacccta actataaaac aggagaaaat tatgcttatc ttggtttgtc tgccaatttt
    30841 cttatttttg atgaatatgt ggcaatgatg gatatgctag gtcgtgaaag taccaccgtt
    30901 attcataaac tcaaacaaat tgtaatgtta ggacgacaag caggcttctt tttaattctt
    30961 gcctgtcaac gtccagacgc aaaatatttt agtgatggga ttcgggacaa ctttaacttc
    31021 cgtgtggctt tgggtcgtat gtctgaaatg ggctttggta tgatgttcgg aagcgataca
    31081 caaaaacaat ttttcttaaa acccatcaag ggaagaggtt acgtggatac aggaaaaagt
    31141 gtgattagtg agttttatac accccttgta ccaaaaaggt acgatttctt aggagaaata
    31201 ggaaaagtca ttcaaaaaaa gcaatctgag cctgtaccgc acgaagtgaa aggtacaggt
    31261 tcagacttgc tttgattggt gtggcgttag ccacgccaat cctttagccc cctctatcta
    31321 acaggggggc acaaatacaa ctgaaaacag gcaattctca tcaaccaatg ttgatggtac
    31381 aaaggattgc ggaaaatatg aaaggtgtaa actcaagggt catagtttac atctttttta
    31441 gattggaggt ttgcgaatgg aaaacgaaaa aatttggatt aaggaattga aagaaaagcg
    31501 actggcttat ggcgtttctc aaaataaact ggcggttgct tctcatatta ccagacctta
    31561 cctatcggat attgaaacag gcaaggcagt ccctactcaa caggtgaaag aagatttact
    31621 gaacgctttg gaacgcttca atcccgataa cccattggag atgttattcg actatgtacg
    31681 gattcgattc cctaccaatg atgtggctca aattatcggt gaggttttac gtttgaatat
    31741 ggattatatg ctacacgaag actttggcta ttattcttat cccgaacact atcgtttcgg
    31801 tgatattgtt gtcctagtct ctcatgatgt aagtaaaggt gttttattag aactgaaagg
    31861 aaaaggctgt cggcaatttg aaaactttct attggctcaa catcggagct ggtatgattt
    31921 ctttcaagat tgcatggaac ataaaggtat tttcaaacgc ttggatttag ctatcaacga
    31981 taaaacaggg attttgaata ttccagattt ggcaaagaaa tgtaaacagg aagaatgcat
    32041 ttccgtcttt cgaagcttta aaaattatcg cagtggtgaa ttggttcacc gtgatgaaaa
    32101 accatacatg ggaaacacac tttatattgg ctcattaaaa agtgaagtct atttctgtat
    32161 atatgagaaa gattatgagc aatacgtgaa aaatgatgtt cccttagaag acgcagaagt
    32221 aaagaatcgg tttgaaattc ggttaaaaaa tgaccgagcc acccaagcca tgaaagattt
    32281 attggcacat caacaggcgg aaaaaacagc ctttgaaatt atcaatcgct atatccgctt
    32341 tgcagataaa gacgacacta aacgtcggag tgattggaaa actaatgaac gttgggaatg
    32401 gtttatcggt aaaaatcgtg gagcattacg cctaaccaca cagccagagc cttattcttt
    32461 tgaacgaaca ttgaactggt tacatcatca agtcgcccct acattaaaaa tcgcaagcat
    32521 tttagatgtt ctcaacggta caaccattat ctccaccatg attcaggaag ccaaactgac
    32581 agaaaaacat gagaaattaa ttgaacaaca acatctagcc atggaggatt tgattacatg
    32641 agccttttaa caaaagaatt aaagaagtta gggtttcagt gtggcattga gtttcaagcg
    32701 tatatacaaa atacagggaa atatacgtct ctcattattg agggaaaacg gcaagctggt
    32761 gataccatct atacctatga tttttacaag gtgagatttt ataataatta taccaatcga
    32821 gtaaccgtct atggagagca tttaacccct tttcaattat taaggcgtgt aaaaagctat
    32881 atctattatc gagaaaaata tcttaaggaa aggaggacaa tcacatgaat tttgggcaga
    32941 atttgtacaa ctggttcttg gataatgcac agtcattggt attgttagcg attgttgtca
    33001 ttggactgtt tttaggtttt aaacgagaat tttcaaaact cattggcttc ttgattattg
    33061 ctctaatcgc cgtcggactt gtgttcaatg cagctggcgt gaaagatgtg ttattaaact
    33121 tatttaaccg aatcattggt gcttaacaga tatttttcat gataaaatag gaagtatata
    33181 ttttgttatg aaaggattta tgaatatgtt tacaaatgat caatttaaat ctcttttaat
    33241 taaaacatta gaaagaaaga gctcttcaaa ttattatgaa ggaggtaacg agattgtttc
    33301 taaaatgaaa atatcagagg taactttaga tgagactgac gattttactt attataaagg
    33361 atataaaaag ggctggaata cgctttgcac atatcttaaa ataagagttc cttttgatga
    33421 tttagacttt tttgaaagtc ataaagattt gattacccag acagcaagct ccatatatga
    33481 taaacaaggt gataatgtat tagtggatac tattttagta ccacttccag agaattacga
    33541 agtaattaac tttagtcagt tgaaaattag tgatgtggtt tcacaagcta ttgaagacgc
    33601 tgagtctttt atgagtaatg gtgaatatca acgtgccttt gacagagttc acactgcttt
    33661 tcatggatat ttaattgaaa tactaaaaaa atatgaaatt acagttccta gagacgaaaa
    33721 tctatctaaa ttatatagta ggatacaaca attaattgaa aaagaaattc aacctactga
    33781 acttgctgat atagtgaaga caacgataag gtcatcaaat ggaatgatta gctctcttaa
    33841 tgaagcaaga aataggcatt cacttgcaca ccctaataca aatattattg gaaagagaga
    33901 agcaaaacta ataataggta tttcaagtac agttacagat tatattagcg gataccttga
    33961 taagtagcgt cattaactga ttgctacttt ttttatgact atttttataa aaaggatgtg
    34021 ataagaattg gaaatgaaag tctatgtggc aaatttagga cggtataatg aaggtgaatt
    34081 agtcggagca tggtttactc caccaattga tgaggaagaa atggcagaaa gaatcggttt
    34141 aaatgaggac tacgaagaat atgcaataca tgattttgag cttccttttg atgtggacga
    34201 atacacgccg attagtgaaa tcaaccgtct atgtgaagcc attcaagaaa tcgaaggtac
    34261 acctatttat aatgaactca aagaaattca aggcatgtgg tttagtagct tggaagaatt
    34321 actggaaaac aaagaggata ttcattgtta tagtgattgt gattcgatgg aagatgtcgc
    34381 ccgttattac gtggaagaaa caggacagct tggtgaagtc ccttccaatt tacaaaatta
    34441 tattgactac caatctttgg gacgtgatat ggaaatagag ggtaattacc tagttacctc
    34501 tcatggggta tttgaatatt gtcagtaagt ttaacaatcc gtgttataat taaattaata
    34561 aatagcacgg agaggtataa attatggtaa atgtatttga aaatcttaaa ctattaaaac
    34621 tagacatgaa agataaaggc tgggtgatag attcctttta ctttcgttac aaacagcaaa
    34681 attatattgt acttgttaag ctatttgaaa aagaggaaaa agttccagaa tatgctctgt
    34741 taaaactaga atttttaaag gaaaacgatt tttcagatat gctagctgtc tatgctaatt
    34801 cggtaaaatt atatacagac acgaaaacaa taagagaata ttttggtatc gaatacagta
    34861 gtaacttggg agatgtttta tttcaattta gccaaactct tgctcgattt attccgacag
    34921 aagttagtga gaagaaaaat gaagaccaaa aagaagccat gtgtttctca ttaagtcaaa
    34981 gtgattcaga agatcccaga aaaaaatatt gtttttcagt tagaagaaat cctttaaagg
    35041 gaaatggtga gctgggaaaa cgaagtcctt ttaatgacaa taaaacgaga ttgtatagac
    35101 ccagcttata tgaacgatta gggtcagata ccaatttaag tttcagatat tcaatgaatc
    35161 cagatgatga agaaactgat gaaggtatta ttgcaaaatg gacaaaaaat aaaattgaat
    35221 agttaaagca ttgaaagagc aatcacctat tttgattgtt ctttttctat ttttacggaa
    35281 aggacgtgaa gacatgaaaa aaataagaag ttacaccagt atttggtcag tagaaaaagt
    35341 gatttatgcg attaatgatt tacaactccc tttcccaatt acctttacgc aaatgacatg
    35401 gtttatcgtt tctttgtttg tcgtcatact ctttggcagt ttaccaccac tttctctgat
    35461 tgacggagca ctactcaaat acttagggat tcccattgtt ctcactgggt tcatgtgcca
    35521 aaagaccttt gacggaaaga aaccctatgg atttctaaag tctatcatta cctatgctct
    35581 acgccctaaa gtaacctacg ctggcaaaca aatacgatta aaaaaagaaa caatgaatga
    35641 atcgattacg attgtaagga gtgaacaact agatggcata tccgattaaa tatatggaag
    35701 ataatctcgt atttaatcat gatggcgaag tattcgctta ttatgaatta attccctata
    35761 attacagttt tttaagttcc gatgaaaaaa ttcaagttca tgataatttc tgtcaattga
    35821 ttgcccaaaa tcgtgatggc aagattcatg ctctgcaact agcaaccgaa tcaagtattc
    35881 gagccacaca ggaacaatcg aaaaaagaaa tcactggacg attaaaagag atagcttacg
    35941 aaaaaataga tgaacagacc gaagcgttaa tttctatgat tggtgacaat caagtagact
    36001 atcgcttttt tattggtttt aaactctacc tcaatgaaca ggaagtatcc gtaaaaaatg
    36061 ttgggaaaga aattcaaaaa gcatttgcgg aattctttca tggtgtgaat cacaaattaa
    36121 tgggcgattt tgtttctatg cctatggcgg aaatcgaacg cttttctaag atggaacagt
    36181 tgttagaaag taaattatcc agacgctttc agattcgtaa attggagaaa gatgattttg
    36241 gttatattat tgaacatctt tacgggcaaa caggtgtccc ttttgatgac tacgactacc
    36301 atttaccgaa acgatacgaa gataaaaaag tgttggtaaa gaaatacgat attctcaaac
    36361 ccactcgctg tttaatcgaa gaaaatcaac gctatttacg gattgaacag gaagatacca
    36421 ctacttatgt ggcgtatttt acaattaata gtattgttgg tgaattggat ttccctaata
    36481 gtgaaatttt ttattaccag caacagcagt ttactttccc cgttgatacc agtatgaatg
    36541 ttgaaattgt cgccaataaa aaagccttat ctaccgttcg caataaaaag aaagaactga
    36601 aagatttaga tagccacgca tgggaaagcg acaacgaaac cagtactaat gtggtggacg
    36661 ctttagaatc tgtcgatgaa ttagaaagta atttagacca aaccaaagaa tctatgtaca
    36721 aactaagcta tgtggtacgg gtatcagcaa agaatttgga cgagctgaaa caacgttgtg
    36781 atgaagtaaa agatttttat gatgatctgt ctatcaaatt agtacgacct tttggcgata
    36841 tgctaggctt gcataatgaa tttattccct caagcaagcg atatatcaat gactatattc
    36901 aatatgtcac gtcggatttt ttggctggtc ttggtttcgg tgctacacaa atgattggtg
    36961 aaaattctgg tatttacgtc ggttacaatc tcgatacagg cagaaatatt tatctccaac
    37021 ctagccttgc aagtcaagga attaaaggct ctgtaacaaa tgcattagcg tccgctttta
    37081 ttggttcatt aggtggcgga aaatcattct ctaacaatat gctggtctat tattcagtac
    37141 tctttggcgg acaggcaacc attgttgacc caaaagctga acgtggtgaa tggaaagaaa
    37201 ccttacctga tattgcccat gaaatcaata ttgttaatct cacgagtgag aacgacaata
    37261 aagggttact tgacccttat gtgattttaa aactcccgaa agattcagaa agccttgcca
    37321 ttgatattct cacgttctta acaggtattt ccagccgaga tagcgagaag tttcctgtcc
    37381 tgcgtaaagc tattcggagt gtaactcaaa gcaaacaacg agggttgtta ttggtgattg
    37441 atgaattgcg aaaagaagat acgcccatca gcaatagtat tgctgaccat atcgaaagct
    37501 ttgtcgatta tgattttgcc catctgttat tcagtgatgg cagtgtcacc caatccatta
    37561 gcttggaaaa acaactcaat attattcaag tggcagattt ggtcttaccc gattccaata
    37621 gctcttttga agaatacact accatggaat tattaagtgt ggcaatgctg attgtcatta
    37681 gtacctttgc tttagacttt atccactctg accgttccat ttttaaaatt gttgaccttg
    37741 atgaggcttg gagtttttta caagtggcac aaggaaaagc tctatctatg cgattggttc
    37801 gagcaggacg tgccatgaat gcaggggtct atttcgttac tcaaaacgcg gacgatttac
    37861 tagatgaaaa gatgaagaat aatattggct tgaaatttgc ctttcgttcc actgacctag
    37921 tggaaatcaa aaagacctta gaattttttg gtgtggacaa ggaagatgaa aacaatcaga
    37981 aacgcttacg tgaattagaa aatggacaat gtttagtttc agacatctat ggtcgtgtag
    38041 gggttatgca gtttcacccg atttttgaag agttgcttca tgcctttgat accagaccgc
    38101 ctgtgcgaaa tgaggtggaa gaatgacaca aaaacaaaag aaatttcttc actatagttg
    38161 gataacgctc ctttgtgtgg gcgttatttt acttttatta ggcacgctgg gcaatgcagt
    38221 acaagcgaca ggcttagttg atgaaaccat tgatacaagc aatgaatact ccaagtatgg
    38281 tttgaatcaa tatcagcttg attattatgt ggacaatagc tggggctggc ttccatggaa
    38341 ttggagtgat ggcataggac aatcggtgat gtatggattg tatgccatta ctaattttat
    38401 ttggacaatt tctctttatc tatcgaacgc cacaggttat ttggtgaaag aagcctatgc
    38461 cttagatttc attagtcaaa catcccaagc aattggcgaa aacatgcaga cgattgcagg
    38521 cattacaccg aatggctttt ccagttcagg gttttatgtc ggtttcctcc ttctttttat
    38581 tctcattgtt ggaatctatg ttgcctatac aggattggtt aagcgagaaa cgacgaaagt
    38641 gatacgagct gttttaaact ttgtcgtggt gtttattcta tcggcttcct ttattgcgta
    38701 tgcacccgat tatattgcga aaatcaatga tttttccaaa gatgtcagta ccgccagtct
    38761 gaatattggg acaaaaattg ttcttcctaa cacggatagt caagggaaag acagtgtgga
    38821 catgatacgt gacagcttat tctctgttca agtaaagcaa ccatggctat tgcttcaata
    38881 tggctccact gatgtagaag cgttagggga agaacgtgtg gaaagtttat tgtctaccag
    38941 tccagataca aacaatggtg aagatagaga aaatgtagtg attgaagaaa ttgaagatca
    39001 tgacaatacc tatttaaccc taccgaagac gatttccaga ttaggaacag tcttcttttt
    39061 gtttgtattc aatattggta tctcgatttt tgttttcctt ctaacaggaa tcatgatttt
    39121 ttcgcaagtg ctatttatta ttttcgctat gtttttgcca atcagtttcc tattaagtat
    39181 gttgccgagt tttgatggca tgggcaggca tgccattacc aagttattta atgtgattat
    39241 gacaagggct ggtattacct tgattattac cgttgccttt agtatttcca ctatgcttta
    39301 ttcgctgtca gcaagttctc cctttttcat gattatgttt ttacaaattg tgacctttgc
    39361 agggatttat tttaaactgg gcgatttaat gagcctattc actttacaaa gcaacgactc
    39421 tcaaaacatg ggcagacaag tgtttcgcag acctcgtcaa atgatgaatc gacaaaccag
    39481 aagatttcaa cgcagtatga gtaagatttt tcgtggaaaa gcagggtcaa cgaagcaaaa
    39541 gacaatgaca acaaagcaga atcaaaccaa taaagctaac catactcgtc aaaatgaacg
    39601 gactacacca aagaaagaaa cagcactttc caatgtgaaa aagcaacaag gcggtatcgg
    39661 gcaacgatta ggtgaaaaga cagcccatgt attggacacg aaaaatcgtc tagtcaataa
    39721 aagaaagcag gcaaaacaac agatacaggc gacaccaacc catgtcaaat atgcccttca
    39781 tcaaggaaaa gagaatgtca ctcataatgt aacagacttt aaacaatcta tggcagatac
    39841 caaagctcaa cgcaaacaac agcgtatgaa ccagcaggag caaaaacgaa agaacattgc
    39901 tcaaaagcgt ttggagctgg ataaagcaaa agaaaaaaga cgaaaagaaa acccatcatc
    39961 tcctgttcag aataaccagc agcatgttcg caagcgtcag caaaccgtca cgcctgtttt
    40021 gtcacaaaac actaaacgtg aaaatcatca gcgaccattg aaaaaagagc aaaaacaaaa
    40081 gacaccaccg aagcaattca atcagaggaa gctaaataaa agaacggata agcgaggaca
    40141 acaaacatga agctaaaaat aacagtgatt tgtagtgtgg tcttctctct cttctttttt
    40201 ctcttattat tcctagtcat tttctttgca gatgatacgg acagtggcga aaacaacaag
    40261 gattcttcta ttccacaagg cggtgtgacc gtttcaccag aagtgttggc acaccgtccg
    40321 ttgattgaaa aatatggtaa ggaatatggg attgaagact atgtttctta tatcttagcc
    40381 attatgcaag tggaatcggg cggtacagca gaagatgtta tgcaaagttc cgaatctttg
    40441 ggtttaccgc ccaacagttt gagtaccgaa gagtccatca aacaaggggt taaatatttc
    40501 agtgaattat taaccagtgc agaacaacaa ggagtggata tagattctgt tatccaatct
    40561 tataattatg gcggtggctt tttaaattat gtgaggagtc atgggaaaaa atatacctat
    40621 gaattagccg aacagttttc taaagagaag tcgggtggtc aaaaagcaga ctatcccaat
    40681 cctatagcca tacctgtgaa tggtggttgg cgatataact atggaaatca gttttatgtt
    40741 cagttggttt cacaatacct aaccgacact tccccaacag aatttgatgg tgaaaccgtg
    40801 caagtcatta tggacgaagc cttgaaatac gaagggtttc cctatgtctt tggaggggcg
    40861 tcgcctacca cctcttttga ttgtagtggc ttaatacaat gggtgtatga caaagctggc
    40921 atttctctcc ctcgtgtcgc ccaagatcag tatgacgcta cgcaagaaat ctctatggaa
    40981 gaagcccaag caggcgacct tatcttcttt cattcaacct ataatgcagg cacatatgtg
    41041 actcatgtgg cgatatattt agagggaaat cgcttttatc atgcaggcga cccaatcggt
    41101 tatggcgact taagcagtcg ttattggcaa gaccatctga ttggggctag acgtgttatt
    41161 cataactaag aaaggaatga atcaaatgat tataaaaatc gagcgaaaag aaaagaagga
    41221 gaaaccaaag aaatctaaaa aaccgagcaa gcaaagaaaa gttccgatga ttaaagttgg
    41281 cacgcataag aaattaacct ttgttttatg ggttttattg attggtagtg tcggatttgg
    41341 aatctataaa aattttactg ccattgacac tcatactgtc cgtgaaacag aaatcattaa
    41401 acagcagatt gtcgatacca accaagtaga aagttttgtg aaatcctttg cgaaagacta
    41461 cttttcgtgg caacaatccc aagaagccat tgataaacga aatgaaaaat tgacccatta
    41521 tttgacggaa gaattgcagg tattaaatga agaaatgatt cgtaaggata ttcctactag
    41581 ttctagtgtg aacgatatac aggtgtggca ggtttctcaa gtgaatgaga acacctttga
    41641 ggtactgttt tctgttgaac aagttattac cgaagacaaa gacaaggaaa ctatatcgtc
    41701 tagctttcat gtggttgtcc atatagatga atcagataat atggttatta tcaaaaatcc
    41761 gacaatgagt aagaaacctc aaaaatcgga ctaccaaccc aaacagctag aaagtgacca
    41821 tacagtagat acagaaacga tggacgaaat cactagcttt ttagaaacgt tcttccagct
    41881 ctatcctacc gccacagaaa aagaattgac ttactatgta agtaatcatg tgttacctat
    41941 gattaacaag gaatatgttt tcgaggaatt ggtgaatcct atctttacca gaaaagataa
    42001 ccaagtaatc gtgaatgtcg ctgtgaaata tttagatcaa gaaacaaagg caacccaaat
    42061 ctcgcaattt gagttgatat tagaaaaaca agataattgg aagattgtaa aataacaaat
    42121 attggtacat gattacagat actttgtaat catgtactct ttttgataaa aaattggaga
    42181 ttcctttaca aatatgctct tacgtgctat tatttaagtg actatttaaa aggagttaat
    42241 aaatatgcgg caaggtattc ttaaataaac tgtcaatttg atagcgggaa caaataatta
    42301 gatgtccttt tttaggaggg cttagttttt tgtacccagt ttaagaatac ctttatcatg
    42361 tgattctaaa gtatccagag aatatctgta tgctttgtat acctatggtt atgcataaaa
    42421 atcccagtga taaaagtatt tatcactggg atttttatgc ccttttgggt ttttgaatgg
    42481 aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat gcaggaaaaa
    42541 ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta ggaagcgtgg
    42601 acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga attacaattc
    42661 agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata gacacgccag
    42721 gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat ggggcaattc
    42781 tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt catgcactta
    42841 ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat ggaattgatt
    42901 tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta atcaaacaga
    42961 aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa caatgggata
    43021 cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa tcattagaag
    43081 cattggaact cgaacaagag gaaagcataa gatttcagaa ttgttctctg ttccctcttt
    43141 atcatggaag tgcaaaaagt aatataggga ttgataacct tatagaagtt attactaata
    43201 aattttattc atcaacacat cgaggtccgt ctgaactttg cggaaatgtt ttcaaaattg
    43261 aatatacaaa aaaaagacaa cgtcttgcat atatacgcct ttatagtgga gtactacatt
    43321 tacgagattc ggttagagta tcagaaaaag aaaaaataaa agttacagaa atgtatactt
    43381 caataaatgg tgaattatgt aagattgata gagcttattc tggagaaatt gttattttgc
    43441 aaaatgagtt tttgaagtta aatagtgttc ttggagatac aaaactattg ccacagagaa
    43501 aaaagattga aaatccgcac cctctactac aaacaactgt tgaaccgagt aaacctgaac
    43561 agagagaaat gttgcttgat gcccttttgg aaatctcaga tagtgatccg cttctacgat
    43621 attacgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa gtacaaatgg
    43681 aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta aaagagccta
    43741 cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac atcgaagtgc
    43801 cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg ttgggaagtg
    43861 gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt caaaatgcag
    43921 ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat gtgacggatt
    43981 gtaaaatctg ttttaagtac ggtttatact atagccctgt tagtactcca gcagattttc
    44041 ggatgcttac tcctattgta ctggagcaag cctttagaaa agctggaaca gaattgttag
    44101 agccatatct tagttttaaa gtttatgcac cacaggaata tctttcacgg gcatataacg
    44161 atgctcccaa atattgtgca aatatcgtaa atactcaact gaaaaataat gaggtcatta
    44221 ttattggaga aattcctgct cgatgtattc aagattatcg caatgattta acttttttta
    44281 caaatgggct tagtgtttgt ttagcagagc taaaaggata tcaggttacc actggcgaac
    44341 ctgtttgcca gacccgtcgt ctaaatagtc ggatagataa agtaagatat atgttcaata
    44401 aaataactta gtgcgtttta tgttgttata taaatatggt ttcttattaa ataagatgaa
    44461 atattcttta atatagattt gaattaaagt ggaaaggagg agattgttat tataaactac
    44521 aagtggatat tgtgtcctat ttgtggaaat aaaacaagac tacgaatacg agtggatact
    44581 atacttaaaa atttcccttt atactgcccc aaatgtaaga acgaaacttt aattaatgtt
    44641 caaaaaatga atataataac aatcaaagag ccagacgcca agacgcagag ccgataattt
    44701 gagaaatgaa actctcatct tatcggctct ttttgtttat ctgaatttta ctgactagcc
    44761 ttcaatattt cttgcttcat tgataccttt tgctagtgct tccattaagg atagttcttt
    44821 gtctgtaaag ctatccatgt atttttctac ctgtaacctt cgagtgcttt taatcaaatt
    44881 atctgtaggt aagaaaaatt catcaataga tacatggagt aatgatacaa gatcatacag
    44941 cacttgtgta cttgggtgtt gtcctttgtt ttctatattt gttaaataac gtgggtcaat
    45001 ttcaatcatt gttcccactt gttcacgagt gagaccccgt ttcattcgag cctctttaat
    45061 cgctaaacca acggctctaa aatcgtattt atcttctttt ttacgcatac taaatcacct
    45121 ctatacattt tactgttcct atataaccat aaacaggtat agaaaaacat gttatatagt
    45181 ttatgagttc ctatagaaca ctgtggaatt tattaatgcg atgaatccaa tttcaaatag
    45241 aaaggtcgct gattttattt acctatacaa ctttataaaa tttagtcata ctcctagaaa
    45301 gtagataaaa ttggcgactt aatggaggga aaagtcgcca tgagaaagat aatctgtcat
    45361 ctagttctct taattaagtt cttatcaaaa aaacttatcc acctgtactg gatagatatg
    45421 accatcaatg tggttttgca gattacatag atagaaaaat caaagcatat gaacagagaa
    45481 aacaatctgt ttatgtgctt ttttggtcac ttaataaata tcttttagga tttctcttca
    45541 tttatgcaac aaatccccct ttcgtgtcgg ggtttagtat gaagggagat aaagaagcac
    45601 atgccactcc ctttcacgac agaaaggggg tgaaaagcat gaaaccatct tcttttcaag
    45661 aaaccataga aaatcagttt gactatatct gcaaacaagt tattgaagat gaacgaaaag
    45721 attacttcaa acatctagac agactatcag caaaagaagt ctcgttttct gatatagata
    45781 actaccttgt caactctttt tctactgttg atacgtacgt cactgatttc caactattta
    45841 aattatttgg attaagaatc aatgttgaaa gtgatttatt aagtgaagcc ctgcgtcatc
    45901 tttcagagaa aaaacggaac attattttac ttcattactt tatggatatg agtgatgtgg
    45961 agattgcgga gttactaaat ttgaatcgtt cgactgttta tcgtcatcga ataagtggac
    46021 tagccatgat taaagaattc atgaaggagt gtaaagaatg aaaacagctt atccaagggt
    46081 tcccttcccc ctcattgtaa aggcgacaga tggcgacgtg gaagcaatta atcagattgt
    46141 taaacattat cgagggtata cctcaaaacg ttcattacgt cgcatgacag acgaatatgg
    46201 aaattctcat atggttattg atgaaaccct acgtggcaga atggaaacga aactcatctc
    46261 taagatttta tcgttcgaaa ttaaatagtc ccattttttc gtggaagcgt gtcgaatcgt
    46321 atccacgctt cccgatttgg gaggtttgtt attccatcaa agcatattgt gtgttcagta
    46381 ggttttgata ggctaacaag ccaaacgttc tttgacaacc aaataaaggc aatcgaatac
    46441 gtttcggtaa gaaaagagct gatgaactaa cacgccatga cctacaaaat tagtgagcga
    46501 ttcatgttag taattcgaaa gtaatcttta gcaggattgc tgccatgact ttcttatcgt
    46561 gataatgata ctcccgtata gccatagtcc gagcgttaga agcgtcacag gcaatgggta
    46621 cggctacatg agaaccatgc agaagtgaaa ttcctgtgag ctttgctaga gctgttcgat
    46681 tgctaagata ttcttctctt gtcagtgtat tattataaaa ctatttgata taattatagg
    46741 tgaatattgg agttttccta gcctataatt gggaaaggag taataatgat aacggtcaca
    46801 aaaaaggatt tagttgagct aggatatgga acttcttttt cagcagacat cataaaaaaa
    46861 gcaaaagaat tgatgattac aaaagggcat atctactatc aatctcgaaa gctagataga
    46921 gtccctcgtg aagctgttga agaaattcta ggaattcggt tttcaaatga aaacaggtct
    46981 gagtagtttt tgcacagtaa ggagtaaaaa ctatggttaa agacccaata aaaaaagcaa
    47041 agaatggaac ctattatttt cgtgcaaatc taggttatga ttctaaaggg aaaaaaattc
    47101 aaaaatatcg tagtggattc actactaaaa aagaagcaag agaagaatat tcgaaactgc
    47161 tattgatgaa accagaagaa ttaagtgaga ataaggataa aatgacgttt aaacattata
    47221 tctttgaaat tttccttcca tggtataaga cacaggtaaa gctcagaaca tatgaaaatc
    47281 gcttaccaac tattaagaag catttctctt attttgataa aatggctgtt tccgatattg
    47341 agcctattga tgtgcaaaat tggcaactaa aattatcaaa gaagtgtaag tcttcttatg
    47401 taagagctgt tcaaggacta ttttcagttg ctatggatcg agcaattgtc cttgggataa
    47461 ccaccacaaa tccatctaag attattggca atgtgaaaaa gcaaaagtct aaaattgaat
    47521 tttggacaaa agaagaattt gaaaaagtaa tctctctaat ttacaaagaa gattactatc
    47581 aacacttttt atttatctct ctgtggtttt tatttatgac tggaatgcga attggtgaag
    47641 ctactgccat tcaatgggaa gatattgatt ttgactcagg agtactaacc atcaacaaaa
    47701 cactctatta caagaatcaa tcgaattata gatttgttga accaaaaaca aaggcgagcg
    47761 ttcgtcatat tgtattagat aaatgcacat taacttattt atccgaatgg aaggaagtac
    47821 aacaaaatct aattcagaca gactttgtaa tgagctataa cggtattcct acccaaaaac
    47881 atacactatc atatgctatt gaacgctatg ctaagctggc tggtatccat cgaatcagaa
    47941 tccatgggtt acggcattct catgcttcct tgttaatcag tatgggagaa aatccactta
    48001 tcattaaaga tcgtctagga cacgaagata ttgagacgac tttaggaacg tatggacatc
    48061 tttatcctaa cagtaatttc gaggtagcta acaaattaaa tggagccatt tcctttaaag
    48121 aagcaaaaca aaattatgat acttcaccaa agaatcaatt tactgtagac tacttgcgaa
    48181 acaaagaaat gaaaaaagtg caataaaagt gcagtaaaaa gataagaaga gccagaaacc
    48241 cttggtataa gaggatttct agctctccta caactattcc cactccactg ttgctggtgg
    48301 tttagaagtg atgtcataca cgatacggtt gacgtgggct acttcgttta cgatacgtac
    48361 agagattttt tgcaagactt cccatgggat acgggcaaag tcagcggtca ttccgtcgat
    48421 tgaagttaca gcacggatac cgactgtgta gtcgtaagta cgtccgtcac ccataacacc
    48481 gacagagcgg atccctggaa gaacagtgaa atattgccag atatcacggt caagtccagc
    48541 agctgcgatt tcttcacgca agatagcatc agattcgcgt acgatttcta gcttgtcttc
    48601 agtgatttcg ccaagaacac gaataccaag accaggacca gggaatggct gacgccaaac
    48661 gattgaatca ggcatgccta actgagtccc taattcacgg acttcgtctt tgaataatgt
    48721 gtttaatggt tcgatcaatt caaattgcat atcttctggc agtccaccta cattatggtg
    48781 agatttgatc gtctgtgctg tttctgtacc agattcgata acgtcagtat acaacgttcc
    48841 ttgtgctagg aaagagacgc cttcttcacc agcaagtttt gttgcttcgt catcaaaaac
    48901 atatacgaat tcattcccaa tgattttacg tttttgttct gggtcagata cacctttcaa
    48961 cttgtctaag aagcgatctc ttgcatcgac tttgatgatg ttcaagccga attttccgcc
    49021 tagactttcc attacttgtt ccgcttcgcc tttgcgtagc agaccgtggt caacaaagat
    49081 agatgtcaat tggtcaccga tcgctttttg taaaagaacc ccaacgacac tagaatcaac
    49141 gccacctgaa agaccaagca agactttttt gtcaccaact tgttcacgga ttttttctac
    49201 ttgcatatcg ataaagttat ccattgtcca gttaccttca cagtgacaaa catcaaaggc
    49261 aaagtggcgc agcaattcga ttccgtattc ggaatgacgt acttctgcat ggaattggat
    49321 accataaaaa ttacgtgttg tgtcttggat agaagcaatc ggacaatctt tgcttgttcc
    49381 gactgtttca aagccttcag gaactttagt taccaagtca ccatggctca tccatactgt
    49441 ttgttgtttt ggtgtttctt taaacaagac agcttgatcg cttgttactt ctaacaaggc
    49501 tttcccatat tcgcggtttt tagcaggctc tacggaaccg ccaagtttgt acgtgatcaa
    49561 ttgcatacca tagcaaatcc ctaatacagg aatacctaaa ttgaagatct caggatcgat
    49621 cccaaatgca ttctcatcat atacactgtt tggtccgcca gaaagaatga ttccctttgg
    49681 attcatcgct tttacttctt ctgcagtaat gcggtggctc aataattcgg aaaagactcc
    49741 aagatcacga atacgtcttg tgatcaattg gttatactga ctaccgtagt ctaatacgat
    49801 aatcttttca acgttcgtca tatcggcaac gtttgtcaaa tttattaccc ctatcccttt
    49861 aaattttatc tcaaaatagt caaactattt taaaatgcta atattttcgc atgaaaatcg
    49921 aatcgatgat atgattttca gttttatgga gaattatatc ggctcttcct cgtgtaggca
    49981 agatatattc ctgtaaattt ttcaaattca catttttcca tacatctttt gccattttaa
    50041 aggcttcttc acgatctccg atagcaaaac gataataata attctctgga ttttggaaag
    50101 ccgtatccag taacgcacca aaacgatcca aataccattt ttcgatcagc acgggatcgg
    50161 catcgacata gacagaaaaa tcaaaaaagt cgctgacgta gatttgctga ttcgcaggta
    50221 attgaagcgt attgatcccc tcaacgatca agatatcagg ctgctggatc aattcgtact
    50281 tgtctggaat gatatcatac acatcatgtg agtaaacagg tacttttatc tcttcctgac
    50341 cagattttac acggttcaag aaatcgatca gcatctccat atcataactt tcaggaaatc
    50401 ctttacggtc catgattcca cgctctttta atatacgatt tggataaaga aatccgtcag
    50461 tcgtgatcag ctgaacgttt cttcgtttga aggtacgaga caaaatcgtc tgcagcagtc
    50521 tggctgttgt actttttcca acggctacac ttccggcgat cccgataata aaaggcggta
    50581 cttctacgta tttatgaaga aataaacctt tactcaagaa caaagattca aattctttca
    50641 tataaagata aatcagatga gcaagaggta catagatatc tcgaacatcc tgcatggaaa
    50701 tgcggtcatt caaacttttg atattatcta gttcatcttg tgtcaaaggt gcttgcccat
    50761 tacgataaaa ttctcgccat tcttctcttg ccacacggta gtagttcatt ggatcattca
    50821 tattagcctc ctgcgttctc ccatcaatgg aactatttta acacaaaata aacgcaaacc
    50881 ccaccactta agagagattg ccgatctttt tgtataatct ttataataga aagaaacgga
    50941 gtcttattct tgacttgcgc acggatacat aaaaggatag actgttgtca tgaaagaaat
    51001 gagaaggatg gaagacatga caaatcatta ctattctgaa cgcccagata cggcgcacga
    51061 ttttgaacaa tgggcttttg agttaaaagg cagaaccttt caatttgtaa cagattctgg
    51121 tgtattttca cgtgaaacag tggattatgg ttcacgtgtc ctgattgatg ctttcgattg
    51181 ggaagagtta cctgatgaag gaaagatctt agatgtggga tgcgggtatg gaccgattgg
    51241 gttagctttg gcatttgcga cacagcggtt tgttgaaatg gtcgacatta atgaacgagc
    51301 ggtaagtcta gcgcaaggaa acgcaaagcg taaccaaatc gaacatgttg atatccatca
    51361 atcgaatatc tatgaagcag ttcatgaaga aacctatgca gctatcgtaa gcaatccgcc
    51421 gatccgtgct ggaaaaaaag ttgtacatga aattttgaca ggcgcatatc ctcggttgaa
    51481 gaagggcggt acactgacaa ttgtgatcca gaagaaacaa ggagcgccga gtgcgcaaaa
    51541 gaaaatggaa gaaacatttg gtaatgcaga aatcgtcaca aaagataaag gatattatat
    51601 catcaaaagt gtgaaagaat aactagctga aaaatagtgg agcgacgaaa gagtggaact
    51661 gggcgtgcat gtacgggtac gtatcagttc tttttttgtt gagaagtttt taaaaacaaa
    51721 gaactatttt ttcttcaaaa agaaatagta ggaacagagt cgttgttttt tacgataaaa
    51781 taaataagat acagaacttg tatagaaggc tgccaagtcg gtagataaag gaggttttta
    51841 tcaaaaaaca tactttcctt ttttctctat tcttttcttg ggggttttgg tacactgata
    51901 gggaatttag atagaaggga gccaatagga tgaagctgac catcagagat atcgcagaaa
    51961 tggcaggcgt atcagtaaca actgtctcac agattttgaa taacaaagga agcagattta
    52021 gtgataagac aagaaaaaaa gtgttgtcga tcgtgaatga acatcattat aagcccgatt
    52081 atttcgcttc aaatgtgatc aatcgacatt caaagaccat cggaatgatc gtccctgatg
    52141 tcactgattt cttcttctcc aaactgatcg aaggtgtaga gagctatttg aatcctttgg
    52201 gctatgtgat catgttatgc aattctcgtc atagccaaga aaatgagatc aagtatttac
    52261 aagagctttc ccaccgctca gtggacggaa tcttgctggc cacaccaaat attttacctg
    52321 agaaatatgc attagacagc ggtttttatc aaaaaatgcc aatcatttta atcgatcgcg
    52381 gattgaatcg tcgggataac ggacggctta tcgtaaagga atatgagggc gcctatcaag
    52441 ctgtttcgct gtttattgaa aatggccata cgaagatcgg catgctgaag gaaaccactg
    52501 gatactatca attagaagaa cgtttcaacg gatatcgtca tgcgctgaaa gatcatggcc
    52561 tgccttttaa tgggaaattt gttgaacatg gagagttgac tgtccaaggt ggatatactg
    52621 catcaaaaaa attactcaaa cataaagata tcacggctat tttttgcggg aatgatgcca
    52681 tggcgatcgg atgctatcag gcgatcgatg aattgggcaa aaaaatccca gaagatatct
    52741 cagtcatagg attcgatgga ttaaagctgt cagaatacat gattccgcaa ttgacgacag
    52801 tgcagcagcc aagttttgat attggatttt atgctgcacg tttcctgatc gatacgatcg
    52861 aatttcctca aagaaaagtt ccgaacaaag tgttcgaaac aaaattaatt attcgtgaga
    52921 gcgtaaaagt attgacaaag ggctaactcg gcggtatatt gcttatgtaa gcatttacaa
    52981 aggctagtta gtgctttttt tatttttagt aaaccagttt actaaagtgg tttacctttc
    53041 ctaaaaataa tgtataatac cgaatgaaga caaggaggat caggcaatgc gaatggtgga
    53101 tctgattgaa aaaaagaggg atggaaacga gctgtcgaaa gaggaaatcg agtacatcgt
    53161 cacgaactat acgaatggaa agattccaga ttatcaagtc agtgcattat tgatggcaat
    53221 tttttatcaa gacatgacaa atgaagaaat cacgaactta acattggcga ttgctaattc
    53281 tggtgatgtc atcgatttga gttctcttga aggaataaag gtagataagc attcgacagg
    53341 tggcgttggt gacacgacca cattgatttt agccccccta gtagctagtg tcggagtgac
    53401 agtggctaaa atgtctggac gcggtctagg ttacacaggt ggtacactag acaagctaga
    53461 agcaattccc ggatttcaga tcgagctttc ggatgaagaa tttgtacgca ttgttaatga
    53521 aagtaaagta gcggtaattg gtcaatcagg aaacttggca ccggcggaca aaaaattgta
    53581 tgccttgcgt gacgtcacag cgaccgttga ttctcttccg ctgattgcca gttcgattat
    53641 gagtaaaaaa atcgcggcag gagcagatgc aatcgttttg gatgtgacca ctggagacgg
    53701 tgctttcatg aagaacatcg aagatgcaag acgtctggca aagaccatga cgagcattgg
    53761 gaaactggct aaccgagaaa cagtggcggt tatctcagat atgtcagaac ctcttggcga
    53821 agctatcgga aatagtctag aagttgtcga ggcaatcgaa acattacaag gaaatggtcc
    53881 agaagatcta gtagaaatgt gctacgcctt aggaagccaa atggttgttc ttgctggcaa
    53941 agctaagaca accgatgaag caagaacgtt gcttcaagaa gctctggaat caggtaaagc
    54001 gttagcaaaa ttcaaagaaa tgatccaaaa tcaaggggga gacccagcga tcgtggaaca
    54061 tccagaacga attttgactg cacgctacac aatggagctt cctgctaaac aaagcggagt
    54121 tgtgtcaaaa atcgtggcaa atgaattagg aattgctgca atgatgctag gtgctgggcg
    54181 taaaaccaaa gaagaagata ttgatcacgc tgttggattg aaactgcata aaaaaattgg
    54241 tgacactgtg acaaaaggtg agtcactatt gacgatctat agtaacgacg aagaaatcac
    54301 ttctgtcatt gaattattat ataaaaatat tgaaattggt gaatcggcaa tgaagccaac
    54361 gttgattcat gacatcatca cagaataaag gaaaaaagcg gactttaccg ttttaaagaa
    54421 aaggggaaaa gaaatggaac taaaccgaat gatcgaccat actattttga aagcagacgc
    54481 atctaaagaa gctgtgatgc aaattatcga agaagcaaaa aaataccatt tttattctgt
    54541 ctgcatcaat ccagcatggg ttgcgctagc gaaagaacaa ttacaaggtg agccagtagc
    54601 cgtatgtaca gtaatcgggt ttcctctagg agcaaacaca cccgagacaa aagcatttga
    54661 aacaacagat gccatcaata acggtgcaga tgaagtcgat atggtcatca atatcggtgc
    54721 tttgaaatca aaggatgatc aacaagtcca aaaagatatc gaagcagttg ttgaagcagc
    54781 aaaagatcgt gcgcttgtca aagttattat tgaaacatcg ttattagata gagaagaaat
    54841 catccgagct tgcgaaatag caaaagctgc aggcgctgat tttgtcaaaa catcaactgg
    54901 tttctcaaca ggcggagcaa aggtagagga tgtccgtttg atgcgtgaaa ctgtaggacc
    54961 agaaatgggt gtcaaagctt ccggcggtat ccataacgaa gaagaagcaa tggcaatgat
    55021 cgaagctggt gctacaagaa tcggaacaag cgcaggagta gcaatcgtat ctggttcaac
    55081 tggtgaaggc tattaatttt ttcaaaggag aagctcatgg cagaactcaa acaagaatgg
    55141 atcaacacag ctattgaagc gttagataaa gcctatgttc cttattccca ttttccggta
    55201 ggcgcttgtc tcgtaacgga atcaggcaag atttatcaag gcatcaacat tgagaatgca
    55261 tcatttggat taacgaattg tgccgagcgc acagcttttt tcaaagcagt atctgaagga
    55321 gaaaaaacat ttacgcatct agtcgtagcg gggcacaccc ccgatcctat ctctccttgt
    55381 ggtgcatgtc gacaagtaat ggcagaattc tgttcccctg atatgccggt tacgctagta
    55441 ggagacaatg gtgtgacgaa ggcaacgacc gttcgtgcac tgctgcctta tgcatttact
    55501 gaaaaagatc tataactcat gttcattcag tcagctgact gttgaaaaat aaaacaatta
    55561 ttttaggagg ctttacagaa atgaaaaaag caaaattatt tggtttaggt gctgtcgcac
    55621 tagcagcagg gttattttta ggtgcatgcg gcaacaacgg ctctactgat tcatccggtg
    55681 gcaaaagctc atcagacaca acaactgcag cattgatcac agacacaggt ggtgtagacg
    55741 accgttcatt caaccagtca gcttgggaag gactagaaaa atgggggaaa gatcaaggac
    55801 tttcacgagg aaatgatggc ttccaatatt tccaatcttc aaatgaatca gattacatcc
    55861 caaatattga ccaagcattg aatgctggat tcaaaacgat ttttggtatt ggttataaac
    55921 taaaaccagc gatccaagaa caagcaacaa acaatacagg tacgaacttt gttattatcg
    55981 atgatgtcat cgatggatta gataacgttg tatctgcaac tttcaaagac aacgaagctt
    56041 cttatcttgc aggtgttgca gcagcttata cgactgaaac aaacgtagtc ggctttatcg
    56101 gcggtgtaaa aggtgaagta atcgatcgtt ttgatgctgg attcaaagcc ggtgttgatg
    56161 caggtgcgaa agaattagga aaagaaatca aagtattgaa tcaatatgct ggtgacttct
    56221 ctgctccaga taaaggacgt tcaattgctc aaggtatgta tgcacaaaac gcagatatca
    56281 tcttccatgc ttcaggcggt acaggtaacg gtgtattcca agaagcaaaa tcattgaacg
    56341 aatcaggcga caaaaaagtt tgggttatcg gtgttgaccg cgaccaatca gacgaaggcg
    56401 aatacacatt aaacggcgaa aagaaaaact tcacattgac atctacactg aaagcagttg
    56461 gaacagtagt agaagatttg gcacaaaaat cagcggacgg taaattccct ggcggcgaac
    56521 acactgttta tggattgaaa gaagacggtg ttggtctaac agaaggacaa ctttctgacg
    56581 aagcgaaaaa agcagttgat gaagcaaaag aaaaaatcat ttcaggtgac gtaaaagttc
    56641 cagaaactcc tgaagaaaac taaaaccatt tctatagcct tgttagacac atgtttgaca
    56701 aggctatggt ttgattagaa caagaattgt tcatttatcc aagctgcctt gtgacagttt
    56761 ggataaggga acaactccct gaagtaatgt ttgtttcaaa agaagaacgc tcactaagcg
    56821 tgaatcttag tcaatcgttg ccctagatag aaatcgttag gatgtgaaaa aaaggtggtt
    56881 caagaaaata ttgtcataga aatgcagaat attaccaaag aatttggaac attcaaggca
    56941 aatgacaaca tcaatttaca agtaaaggca ggagaaattc atgcgttgct tggagaaaac
    57001 ggtgctggca aatctacatt gatgaacgtg ctttccggat tattagagcc gacatcaggg
    57061 aaaattttga tgcgtgggaa agaagtaaag atcacaagtc cgaccaaagc caaccaatta
    57121 gggattggga tggtccatca gcactttatg cttgttgatg cctttactgt aacagaaaac
    57181 atcgtgttgg gaagcgagcc tagtcgcgca gggatgcttg accataaaaa agcacgaaaa
    57241 gagatccaaa aagtttctga acagtatgga ttgtcagtca acccagatgc ttacgttcgt
    57301 gatatttcag ttggaatgga acaacgggta gaaattttaa aaacacttta ccgaggagca
    57361 gatgtactga tttttgatga gccgacagct gtattgaccc ctcaagaaat tgatgaatta
    57421 atcgtgatca tgaaggaatt agtcaaagaa ggcaagtcga tcattttgat tacgcataag
    57481 ttagatgaaa tcaaagcagt agctgaccgc tgtacagtta tccgccgtgg aaaaggaatc
    57541 ggtacagtca acgttaaaga cgtaacctca caacaattag ccgatatgat ggttggaaga
    57601 acggtttcat tcaaaacgat gaaaaaagaa gcgaagcctc aagaagtcgt tttgtctatt
    57661 gaaaatctag tggtgaaaga aaatcgtgga ttagaagccg tgaaaaactt gaacttagag
    57721 gttcgtgctg gcgaagtact tggtatcgct ggaatcgatg gaaacgggca gtcggagttg
    57781 atccaagctt tgactggttt gcgaaaggca gaaagcggac atatcaagct aaaaggggaa
    57841 gacatcacta ataaaaaacc ccgaaaaatc actgaacatg gtgtaggaca cgtgccagaa
    57901 gaccgtcata aatacgggtt agtcctagat atgacattat ctgaaaatat cgcactacaa
    57961 acctatcatc aaaaacctta cagtaaaaac ggcatgctga attattcagt aatgaatgaa
    58021 catgccagag aattgatcga agaatatgat gttcgaacaa cgaatgaact tgttcccgca
    58081 aaagctttat caggcggaaa tcagcaaaaa gcaattatcg ctcgtgaagt cgaccgagat
    58141 cctgatctgt tgattgttgc aaatccaact cgtggactgg atgtaggtgc gatcgaattt
    58201 attcataaac gtctgatcga acaaagggac aaatacaaag cagtgttact gatcagtttc
    58261 gaattagaag aaattttaaa tgtttcggat cgtattgctg ttatccatga aggagaaatt
    58321 gtcggtatcg ttgatccgaa agaaacatct gaaaatgaat taggtctatt gatggcgggc
    58381 tataccttag aagaagcacg aaaagagtta gaaaaggggg ctggcgcaca tgaatgatcg
    58441 cagcgaaaaa ttccgtaatt tattagtgcc tgtactttca gttgttttag gattgatctt
    58501 aggcgcgata ttgatggctg cttttggttt tcagcccatc caaggttatt cttctatgct
    58561 agatgcagcc cttggttcgc aaagagggat aggtgaaacg ttaaggcaag caacgccgtt
    58621 gatttttaca gcattaggtt tttctgtagc taactcagct gggtttttca atattgggct
    58681 ttctggacaa gcactttgcg ggtggatcgt cagtgtctgg gtggcacttg cgtttccaga
    58741 tctgccaaaa gttgttttgc ttccgttatg cgtgatctta ggtgccttag ctggtgcgat
    58801 ggcagcggct gttccaggtt tacttcgagc attttttgga acaagtgaag tgatcgtaac
    58861 aatcatgatg aactatatct tattatacgt aagcacattt gctttacatg aagtgatgcc
    58921 tgaaagctat cgctcaagtt tggactcttc caatatgatc agtcaaaatg cctcactgcg
    58981 gttaccatgg ttaacacaag cttttggcgg ctctcgcgta aactcaggat tatttttagc
    59041 aatcatcgcg cttattttcg tttggctgct gatgaagaaa acgactttag gatttgaaat
    59101 ccgttctgtt ggattgaatc cttttgcttc tgagtatgca ggaatgagta gtaaacgtac
    59161 gatcgttttg tcgatggtca tttctggcgc tttggcaggg cttggcggtg tggttgaagg
    59221 attaggaacg tatcaaaact tctttgttca aacgacttcg ctatctattg gatttgacgg
    59281 aatggctgtt tccttgcttg gttctggatc agcaatcggt attcttttat cagcgatctt
    59341 gttcagtatt ttgaagatcg gtggacttgg catgcagaca ggagcaggtg ttccgtttga
    59401 gatcgtcaat gtatcgattg ctttgattat cttctttgtc gggatcaact tcctgattcg
    59461 tttcgtcatg gctaaagtct tccaagggaa aaaacaagaa gagatcgttg cgacaataga
    59521 atcgaaacca acgaatcaaa accatgaagg gggcgaacta taatgtcgac tatcgaatta
    59581 attgccttga tccttacttc tacactggtt tattcaacac cgctaattct aacgtcacta
    59641 ggcggaactt tttctgaacg aagcgggatc gtaaacgtag ggctagaggg aatcatggtc
    59701 atgggtgctt ttagttccat cgttttcaac ttgacgatga gtccatcact tggttctatg
    59761 acaccatgga tcgctatttt agtgggtggc gtcgtaggta tcctattttc tctgattcac
    59821 gcagtagcaa cagtcagttt gcgtgctgac catattatca gcgggacagt aattaatctg
    59881 atggcacctg ctttaggtgt tttcttgatc aaagcatggt atggtaaagg tcaaactgat
    59941 aacatcacgc agaatctggg gtatttttct ttcccaggat tagcagatat tccggtcatt
    60001 ggaccaattt tctttaaaaa tacattctta cctgcttatt gtgctatttt gattgctgtc
    60061 ctagcttggg tgatcatctt caagacgaaa ttcggcttgc gcctccgttc agttggtgaa
    60121 aatcctcaag ctgccgacac attaggtatc aatgtatatg ctatgcgtta ttcaggcgta
    60181 ctgatttctg gcttgttagg cggtatgggc ggtgctgttt ttgctcagtc gatttccggt
    60241 aacttttcag ctggtacgat cgttggacaa gggttcatct ccatggctgc tatgatcttt
    60301 ggtaagtgga atcctttagg ggcaatgggt gcctcattgt tctttggttt tgctcaaagc
    60361 ttgagtatca ttggcgcaca attaccagtt atttcttcga ttccgccagt attgctgcaa
    60421 attgctccat atttgctgac aatcattgtg ctggttgttt tcttagggaa agcttctggt
    60481 ccaaaagcaa acgggaagaa ctatatcaaa tcaaaataat cttttagcga ataaaaaggg
    60541 tgggttacgg gaagtgtttt tcgtctcgcc ctttttgttt taaaggcaat aaaaataaaa
    60601 agaaagaagg aataatcatg tttaaacgcg tacatctgat cgtcatggat tcagtaggaa
    60661 ttggagaagc accagatgcc gataagttcg gtgatgttgg ttctgataca ttaggacaca
    60721 ttgcgaaaga agcaggattg aacgttccac atttagagca gcttggttta ggaacgatcc
    60781 gtcctcttga aggtgtggaa tcagtgaaag atcatcaagg ctatgcgacg aaattagaag
    60841 aagtttctgt agggaaagat acgatgacag gccactggga aatcatggga ttgaatatca
    60901 aaactccatt tcgtgtgttt cctaatggat tccctgatga tctgatcaaa caaatcgaag
    60961 aattttctgg ccgtaaagtc gtatgtaaca aaccttatag cggaacagct gttattgacg
    61021 attacggtga acaccaaatg aaaacaggcg atttaattgt atatacttct gccgatcctg
    61081 tccttcagat cgcggcacat gaagaaatca ttcctttaga agaattatat cggatttgcc
    61141 aattcgttcg tgatataaca aaagatgatc cgtatatgat tggccgaatc attgcacgtc
    61201 cgtacgtggg tgaaccagga gacttcacac gaacaagcaa tcgccatgat tatgcgttga
    61261 atccattcgg acacacagtc cttgattctt tgaaagaagc aggaaaggac gtgattgctg
    61321 ttggaaagat caacgatatt ttcaacggac aaggaatcac tgaatctgtc cgcacgaaaa
    61381 gcaatatgga tggcgttgac cagctgctga aagttatgaa aaacgatttt tcaggaatca
    61441 gctttaccaa tttagtagat tttgatgcat tatacggtca tcgtcgggat gtagtcggct
    61501 atgcgcatgc gattgaagaa tttgacttac gaattccaga attgcttgaa gcgatggaag
    61561 aagacgactt gctaatgatt acagccgatc acggaaacga tccgacgttt actggtaccg
    61621 atcatacgcg agaatatgta ccgttattgg tttacagtaa aaaaatgaaa gaacaagggg
    61681 cattgcctca aggatattat tcagatattt cagcaacgat tgctgagaac tttagtgttt
    61741 cttcgactga aaatggcgaa agcttcttga aattattaaa ataatctttt taaataggag
    61801 aaagcaaatg accaagttaa gcgagatgtt acaagaaacg acccagttta tccttgataa
    61861 aggagtaaaa gaaattgatt ttggtttgat tctaggttca ggattaggtg aattagcaga
    61921 tgaaatcgaa gatgctgtaa tgatttctta tgatgagatc ccgttctttc ctgtttcgac
    61981 agtagttggg catgcaggaa agctagttta tgggtctctg gcaggcaaga aagtgttagc
    62041 catgcaaggg agattccact actatgaagg tcattccatg caaacagtga cctatccagt
    62101 acgtgtgatg gccggactag gggcccattc agtcattgtg actaatgcat gtggtggtgt
    62161 caacgaatca tttgtaccag gagatttgat gctgattacc gatcatatca attttactgg
    62221 tgaaaatcct ttgatcggtc cgaatgaaga tgcaatgggc cctagatttc cagatatgag
    62281 tcaagcttat acgcctgact atcaagcaac agcaaaagca gcagcagaaa aactaggttt
    62341 ggatcttaaa gaaggcgtat atatgggcta ttctggacca acttatgaaa cgcctgcgga
    62401 gatccgaatg tctcggacaa taggagccga tgcagtaggg atgtcgactg ttccagaagt
    62461 catcgtagca gctcacagcg gattaaaagt gttaggaatc tcttgtatta ccaacttagc
    62521 agcaggtatg caagcgaatc tgagccatga agaagttgta gaaacaactc agagagtcaa
    62581 acaatctttt aaagcattgg ttaaagaaac attgacatta ttgtaatagg aggaacaata
    62641 aaatgagtgt gcatattgaa gcgaaagaag gcgagatcgc cgataagatt ttacttccgg
    62701 gagatccttt gcgagctaaa tatattgcgg agactttttt ggaagatcca gtttgttaca
    62761 atcaggtacg cggtatgtta ggctttaccg gcaaatataa aggagaacgt atttctgttc
    62821 aaggaacagg aatgggaatg ccatcagcca ccatctatgc ccatgaattg atccagtcgt
    62881 atggtgtaaa gaaattgatt cgagtaggta catgcggtgc attgtcaaaa gacgtccatg
    62941 ttcgtgattt agtactagca caaggtgcag cgaccagttc ttcgatgatc gaaaaaaatt
    63001 tccaagcctt tcattttcct ccaatcagtg atttcaatct attactgaaa gcatatgaga
    63061 tagctaaaga aaagggctat acggttcatg taggaaatgt tctttcggaa gattctttct
    63121 acaaagatga tttgacagag acgttccaat tagctgaact tggcgtttta ggagtggaaa
    63181 tggaagcagc ggctctttat tacttaggcg cgaaatacca tgtgcagaca ttaagtttga
    63241 tgaccgttag cgaccatttg atcaccggtg aagaaacaac agctgcagaa cgtcaatcta
    63301 cgttcaatga aatgatcgaa gtaggattgg aaacagcgat agcagaataa gaaggaaatg
    63361 aaaaagctgc cctgcattaa gtaataagaa catccaagca aaaatagctc ctcatgtttt
    63421 tgacttggct ggacttatta ttgcaaatgt aagcttttga acaccgttta ccaagaggtt
    63481 gtgaatctgc cgtttaactc tgagtcacaa ggaacaattt caaaaaacag cttttcatgt
    63541 ttgatgaata ttgtgacttg tgaccgagaa gttggcagga gaaaaccgtt tatacgaaaa
    63601 aagggactgt gacaaatcgt gtcacagtcc cttttttata gtgtttttta taggtagtat
    63661 tttttagcaa ctgttaagtc atcatttaat tcataaacaa gtggttgacc tgttggaatt
    63721 tcaagatcca tgatgtcttc gtcagagata ccttcgatat gtttagctag ggcgcgtaat
    63781 gagttaccat gtgcagctac taaaacagtt ttgttgtcta gtaatgctgg agcaatttca
    63841 tcttgccaga atggcaaagc gcgttctaat gtcactttca agttttctcc accaggaata
    63901 tcgcgtttgt ctaacattgc gtaacgacgg tcatttgctg cagaaccttc gtcagtttct
    63961 tccattaatg gaggaagagt atcgtaagaa cgacgccaga tgtgcacttg ttcgtcgccg
    64021 tatttttcag ctgtttcttt tttgttcaaa ccttgtaatt taccatagtg acgttcgttt
    64081 aagcgccatg atttgatttg tggtacccaa agttgatctg aatattctaa gatcaagtta
    64141 catgttttga ttgcacgagt taaaacagaa gtgtaagcaa catcaaattc gattccagct
    64201 tctttgattt tgcgtccgcc ttcttttgct tcttcgattc cttctggtgc tagatttaca
    64261 tcagcccaac cagtaaattg gttcaatgca ttccattcac taagaccgtg acgagaaaaa
    64321 actaattttg gcatgtttag ctctcctttt aagataggtt tatatttctg aaattttcag
    64381 ttctgtttta ttgtacaatt ttgtggaaga gatttccatc gaaaaattag ataagattct
    64441 atgagaaaac aagtagagaa tataaaaaaa cgaacagtgc ccacgcaact gttcgttttt
    64501 aggtattaga tgcataattg ctcgatttct ttttcaggta aattgatata tttataacat
    64561 gttccaactg aaacaccgca ttttgaagaa ataaattgga tcgtttcttt tttttcataa
    64621 tagagacgtc ggattttttt gatcgttttt gcatcgattt ttggtcttcc gccgattttt
    64681 ccttttttac gagcttcatc taatccaact aatgtacgtt ctttgatcaa tgcgcactcc
    64741 atgtttgcta ggttttccat taattggaaa tagatttttc ccatttcgcg cgtatcgatt
    64801 ccttcatcaa gactaatcaa gtgcagcccg cgatctttga ataattgcgt gagttctgtt
    64861 aattgccgcg tagatttgcc taatcgatga agttggcaaa tgactagtgc atcgccttgt
    64921 tgcatgtcag cgatcactga ctccaaatga acagcagtag aatcattttg ttccacttca
    64981 tatgtctcat ggaaaatttc ttgacaacca aagtcagata attgatcaac ctgagttgtt
    65041 aaatcaacgt catttatggt tgtgcgtgca taaccaataa ttttcatggt gattcctttc
    65101 tagcagtgat tttctaactg gatataacag taaaaatgta gcataaagta cgtcaaaaag
    65161 atagtttttt cgcaaatttt ccgctgtctt tttttattgg atgatcaagc agtttttctt
    65221 tatttacgac ggattgcgtc aagaatctca acgccttttt ctgagccgac aactacttta
    65281 gaaaccatgt ttaggaaaag cccatgttct actaccccaa caagttcatc taaataggta
    65341 gctaagcttt ctggctgttc gatgacttct agatgcagat caatgatgta atgaccacca
    65401 tctgtggtta agacttctcc gttttcgtct gtacgcaaga cgggttggaa tcttttttct
    65461 tcaaaaatat gaagtagctg ttgggagcca taagggatca cttcaactgg gagtgggaac
    65521 ttcccaagtt tatcgactaa tttagaagaa tcaacgatcc aaatcgtttc ttttgagtac
    65581 gtagcgacta ttttctcgaa aagcaaagca gcgccgccgc ctttgatccc ttgaaaatca
    65641 gcactgattt catcagcacc gtctattgtc aaatcgacta cggggacttc atcaatactc
    65701 tttaacggta ttcctaattt ttccgcttgt tcttttgtcg catttgaagt agtaactcct
    65761 gtgatacgta aaccttcttc acgcatacgg cgaccaatct cttctaccat ataataggcg
    65821 gttgaaccgg tcccgagacc tacgatcatc ccgtccttta cgaatttcgc ggcttcaatg
    65881 ccagctaatt gttttaaatt catctttgcg tccacctttt tttagtttga gcatcgtgct
    65941 ttcctcacta ttttagcgtg atttacggta aaaagatacc attctttttt attccaataa
    66001 agctttttca aaaaaaattg catctcttgt tgacatgttt tttcattcgt gatattctaa
    66061 caaaggtgct ttatctacag gtttctgtga agaaacgtgc tgactgttta tcaaagcata
    66121 tttgataagg atgcagacat tgcatttatt ttttatcaca aaaaaagaac cacctggatg
    66181 tgtggaacta gacgcaaatc gtgggaagga ggaaacaagg aatgcctaca attaaccaat
    66241 tagtacgtaa acctcgtaaa tcaaaggtgg aaaaatctaa ttcacctgct ttgaacaaag
    66301 gatataacag ctttaagaaa actcaaacta acgtaaactc acctcaaaaa cgtggggtag
    66361 caactcgtgt gggtacaatg acacctaaaa aaccgaactc agctttacgt aaatatgcac
    66421 gtgttcgttt gtcaaactta attgaagtta ctgcttatat cccagggatt ggtcataact
    66481 tacaagaaca cagtgttgta ttattacgcg gtggtcgtgt aaaagactta ccaggggtac
    66541 gttaccatat cgttcgcggt gctttagata ctgctggtgt taacgaccgt aaacaaagcc
    66601 gttctaaata cggaactaaa aaacctaaag cttaatttta attattaaac aaatgaaact
    66661 tgcttctact atatagaagt aattactatg aacaatattt cggaaggagg agttacggat
    66721 gccacgtaaa ggtcctgttg caaaacgtga tgttttacca gatcctattt ataactcaaa
    66781 attagtaact cgcttgatca accgtgtaat ggttgacgga aaacgcggga ttgcagctaa
    66841 cattatctat aatgcctttg acttgatcaa agaatctaca ggtaacgatc cattagaagt
    66901 gtttgaacaa gcaatgaaaa acgttcaacc tgttcttgaa gttaaagcac gtcgtgttgg
    66961 gggttcaaac taccaagtac cagttgaagt tcgccctgaa cgccgcgtta ctctaggtct
    67021 tcgttgggta gtaaactacg ctcgcttgcg cggtgaacac acaatggaag aacgcttagc
    67081 aaaagaaatc atggatgctg caaacaacac aggtgcttct gttaaaaaac gtgaagacac
    67141 tcataaaatg gctgatgcca accgtgcgtt tgctcactat cgctggtaag attctctctg
    67201 tttggtcggc ttttataagt cgacctcaga tagtgtcctt atttttagca actagatagt
    67261 aaagagagga gaaacaagga gaatgaccag agaattttct ttacaaaaca ctcgtaatat
    67321 cggtatcatg gcccacatcg atgctggtaa aacgactgct actgaacgta tcttgtacta
    67381 tactggtaaa atccataaaa ttggtgaaac tcatgaagga gcttcacaaa tggactggat
    67441 ggaacaagaa caagaacgtg gtattacgat cacttctgct gctactacag cacaatggaa
    67501 gggtcaccga atcaacatca tcgacacacc aggacacgta gacttcacag ttgaagttga
    67561 acgttcattg cgtgtacttg atggtgctgt aactgttctt gatgcacaat caggtgttga
    67621 acctcaaact gaaacagttt ggcgtcaagc aacaacttat ggtgtacctc gtatcgtatt
    67681 tgcaaacaaa atggacaaga tcggtgctga cttcttatat tcagtatcaa ctttacatga
    67741 ccgtttgcaa gcaaacgctc acccaatcca attaccaatt ggtgcggaag acgacttcac
    67801 aggaattatc gaccttgtaa caatgaaggc tgaaatgtat acaaacgatc ttggaacaga
    67861 gatcgaagaa acagaaattc ctgaagaata ccgcgaatta gctgaagaat ggcgcgaaaa
    67921 attggttgaa gctgtagctg aaactgatga agaacttact ttgaaatact tagaaggtga
    67981 agaaatcact gaagctgagt taaaagaagg tatccgccgc gcaacagtta acgtagaatt
    68041 ctacccagta ctatgtggtt cagcatttaa gaacaaaggg gttcaattac tattggacgc
    68101 tgttcttgat tacttgccat caccgttaga tatcccagct atcaaaggga ttgaccctaa
    68161 aactgatgaa gaagtagaac gtcctgcaga cgacagcgct cctttctcag ctttagcatt
    68221 taaagttatg actgacccat tcgtaggtcg tttaactttc ttccgtgtgt actctggtgt
    68281 tttacaatca ggttcatacg tacaaaacgc aacaaaaggc aaacgtgaac gtgttggtcg
    68341 tatcctacag atgcatgcca actctcgttc agaaatctct gaagtttacg ctggagatat
    68401 cgctgctgct gttggtttga aagacacaac tactggggac acactatgtg atgaaaagag
    68461 tctagttatt cttgaatcca tggaattccc agaaccagtt atccaagtcg ctattgaacc
    68521 taaatcaaaa gctgaccaag ataaaatggg tgtggcttta caaaaactat ctgaagaaga
    68581 tcctactttc cgtgctgaaa caaacgtgga aacaggcgaa acaatcatcg ctggtatggg
    68641 tgaacttcac ttagatatca tcgttgaccg tatgcgtcgt gaattcaaag ttgaagctaa
    68701 cgtaggtgcg cctcaagtat cttaccgtga aactttccgt gctggcactc aagccgaagg
    68761 taagtttgta cgtcagtctg gtggtaaagg tcaatacggt cacgtatgga ttgaatttac
    68821 accaaatgaa gaaggtgctg gtttcgaatt tgaaaatgcg atcgtcggtg gggttgttcc
    68881 tcgtgaatac attccagctg ttgaaactgg tttgaaagat gctatggaaa atggtgtctt
    68941 agctggctat ccattagtag atatcaaagc taaactttac gatggttcat accatgatgt
    69001 cgattcaaat gaaactgcct tccgtgttgc tgcttctatg gcattacgtg cagcagctaa
    69061 gaaagctaat ccagtaatcc ttgaaccaat catggctgta gaagttgtta tccctgaaga
    69121 ttatttaggt gatgttatgg gtcacgtaac tgctcgtcgt ggacgtgttg aaggtatgga
    69181 agctcgcgct ggcggccaac aagttgttcg tgcgatggtt ccacttgctg aaatgtttgg
    69241 ttatgctaca actcttcgtt ctgctactca aggtcgtggt acatttacaa tgacatttga
    69301 ccactacgaa gatgtaccaa aatcagtaca agaagaaatc attaagaaaa acggcggaaa
    69361 agctgaataa tttcttaaaa ccggatagtc ctgcaaagag attatccaaa gagactatat
    69421 ttttaatata gtttcgtgta aaataattat cgatgatatg ggcatgtggt gtaccttgtg
    69481 tacatcatat acctatcaga caaataaaaa atatattgta tttttaggag gacattttaa
    69541 aatggcaaaa gaaaaatttg accgttctaa accacacgtt aacattggta ctatcggaca
    69601 cgttgaccat ggtaaaacta cattaacagc tgcaatcaca actgtactat ctaagaaaaa
    69661 cggcggccaa gctatggctt acgatcaaat cgatggtgct ccagaagaac gcgaacgcgg
    69721 aatcacaatc tcaacagctc acgttgagta tgaaacagat acacgccact acgctcacgt
    69781 tgactgccca ggacacgcgg attacgttaa aaacatgatc actggtgctg ctcaaatgga
    69841 cggagctatc ttggtagttt ctgctgctga cggcccaatg cctcaaactc gtgaacacat
    69901 cctattgtct cgtcaagttg gtgttcctta catcgttgta ttcttgaaca aagtagacat
    69961 ggttgatgac gaagaattac tagaattagt tgaaatggaa gttcgtgacc tattaacaga
    70021 atacgaattc cctggtgacg atgttcctgt agttgctgga tcagctttga aagctctaga
    70081 aggcgacgct tcatacgaag aaaaaattct tgaattaatg gctgcagttg acgaatacat
    70141 cccaactcca gaacgtgaca acgacaaacc attcatgatg ccagttgaag acgtgttctc
    70201 aattactgga cgtggtactg ttgctacagg tcgtgttgaa cgtggacaag ttcgcgttgg
    70261 tgacgaagtt gaagttgttg gtattgctga agaaacttca aaaacaacag ttactggtgt
    70321 tgaaatgttc cgtaaattgt tagactacgc tgaagctgga gacaacattg gtgctttact
    70381 acgtggtgtt gcacgtgaag acatccaacg tggacaagtt ttagctaaac caggtacaat
    70441 cacacctcat acaaaattct ctgcagaagt atacgtgttg acaaaagaag aaggtggacg
    70501 tcatactcca ttcttcacta actaccgtcc acaattctac ttccgtacaa ctgacgtaac
    70561 aggtgttgtt gaattaccag aaggaactga aatggttatg cctggcgaca acgtaacaat
    70621 ggaagttgaa ttaatccacc caatcgctat cgaaaacggt actaaattct caatccgtga
    70681 aggcggacgt acagttggtg ccggtgtcgt tacagaaatc aaagcttaat tcacttaagt
    70741 tttaaagtaa agcaacattt attcggacgt aatcgctcgg aacgaaggtc ttaggatctt
    70801 tgttccgagc ttttttattt attgcaggat caggaaaa
//
LOCUS       DACBZK010000005        69093 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.005, whole genome shotgun sequence.
ACCESSION   DACBZK010000005 DACBZK010000000
VERSION     DACBZK010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 69093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69093
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.005"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(23..391)
                     /locus_tag="IVD66_000398"
     CDS             complement(23..391)
                     /locus_tag="IVD66_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAP6144647.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            complement(1002..2393)
                     /locus_tag="IVD66_000399"
     CDS             complement(1002..2393)
                     /locus_tag="IVD66_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HAP6144648.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            complement(2606..2992)
                     /locus_tag="IVD66_000400"
     CDS             complement(2606..2992)
                     /locus_tag="IVD66_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HAP6144649.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            complement(3048..3671)
                     /locus_tag="IVD66_000401"
     CDS             complement(3048..3671)
                     /locus_tag="IVD66_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HAP6144650.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            complement(3735..4403)
                     /locus_tag="IVD66_000402"
     CDS             complement(3735..4403)
                     /locus_tag="IVD66_000402"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAP6144651.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            complement(4415..4855)
                     /locus_tag="IVD66_000403"
     CDS             complement(4415..4855)
                     /locus_tag="IVD66_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144652.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            complement(4914..5585)
                     /locus_tag="IVD66_000404"
                     /pseudo
     CDS             complement(4914..5585)
                     /locus_tag="IVD66_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5770..6168)
                     /locus_tag="IVD66_000405"
     CDS             complement(5770..6168)
                     /locus_tag="IVD66_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HAP6144653.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(6165..6938)
                     /locus_tag="IVD66_000406"
     CDS             complement(6165..6938)
                     /locus_tag="IVD66_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAP6144654.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(6935..7618)
                     /locus_tag="IVD66_000407"
     CDS             complement(6935..7618)
                     /locus_tag="IVD66_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAP6144655.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(7785..8672)
                     /locus_tag="IVD66_000408"
     CDS             complement(7785..8672)
                     /locus_tag="IVD66_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6144656.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(8669..9538)
                     /locus_tag="IVD66_000409"
     CDS             complement(8669..9538)
                     /locus_tag="IVD66_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6144657.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(9675..10961)
                     /locus_tag="IVD66_000410"
     CDS             complement(9675..10961)
                     /locus_tag="IVD66_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6144658.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            11234..11812
                     /locus_tag="IVD66_000411"
     CDS             11234..11812
                     /locus_tag="IVD66_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAP6144659.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            11812..12741
                     /locus_tag="IVD66_000412"
     CDS             11812..12741
                     /locus_tag="IVD66_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6144660.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            12738..14474
                     /locus_tag="IVD66_000413"
     CDS             12738..14474
                     /locus_tag="IVD66_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP6144661.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(14537..15373)
                     /gene="pheA"
                     /locus_tag="IVD66_000414"
     CDS             complement(14537..15373)
                     /gene="pheA"
                     /locus_tag="IVD66_000414"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HAP6144662.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(15370..15879)
                     /locus_tag="IVD66_000415"
     CDS             complement(15370..15879)
                     /locus_tag="IVD66_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HAP6144663.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(15872..17167)
                     /gene="aroA"
                     /locus_tag="IVD66_000416"
     CDS             complement(15872..17167)
                     /gene="aroA"
                     /locus_tag="IVD66_000416"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAP6144664.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(17180..18271)
                     /locus_tag="IVD66_000417"
     CDS             complement(17180..18271)
                     /locus_tag="IVD66_000417"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HAP6144665.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(18288..19454)
                     /gene="aroC"
                     /locus_tag="IVD66_000418"
     CDS             complement(18288..19454)
                     /gene="aroC"
                     /locus_tag="IVD66_000418"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HAP6144666.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(19456..20520)
                     /gene="aroB"
                     /locus_tag="IVD66_000419"
     CDS             complement(19456..20520)
                     /gene="aroB"
                     /locus_tag="IVD66_000419"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HAP6144667.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(20553..21575)
                     /gene="aroF"
                     /locus_tag="IVD66_000420"
     CDS             complement(20553..21575)
                     /gene="aroF"
                     /locus_tag="IVD66_000420"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HAP6144668.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(22234..23208)
                     /locus_tag="IVD66_000421"
     CDS             complement(22234..23208)
                     /locus_tag="IVD66_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HAP6144669.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(23189..25072)
                     /locus_tag="IVD66_000422"
     CDS             complement(23189..25072)
                     /locus_tag="IVD66_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HAP6144670.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(25090..27315)
                     /locus_tag="IVD66_000423"
     CDS             complement(25090..27315)
                     /locus_tag="IVD66_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAP6144671.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEEKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            27430..28464
                     /locus_tag="IVD66_000424"
     CDS             27430..28464
                     /locus_tag="IVD66_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6144672.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(28531..29544)
                     /locus_tag="IVD66_000425"
     CDS             complement(28531..29544)
                     /locus_tag="IVD66_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP6144673.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKHLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(29622..29810)
                     /locus_tag="IVD66_000426"
     CDS             complement(29622..29810)
                     /locus_tag="IVD66_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HAP6144674.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(30250..30378)
                     /locus_tag="IVD66_000427"
     CDS             complement(30250..30378)
                     /locus_tag="IVD66_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAP6144675.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(30381..31754)
                     /gene="rlmD"
                     /locus_tag="IVD66_000428"
     CDS             complement(30381..31754)
                     /gene="rlmD"
                     /locus_tag="IVD66_000428"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAP6144676.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(31865..32920)
                     /locus_tag="IVD66_000429"
     CDS             complement(31865..32920)
                     /locus_tag="IVD66_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAP6144677.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(32930..34360)
                     /gene="gatB"
                     /locus_tag="IVD66_000430"
     CDS             complement(32930..34360)
                     /gene="gatB"
                     /locus_tag="IVD66_000430"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HAP6144678.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(34357..35829)
                     /gene="gatA"
                     /locus_tag="IVD66_000431"
     CDS             complement(34357..35829)
                     /gene="gatA"
                     /locus_tag="IVD66_000431"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HAP6144679.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(35829..36134)
                     /gene="gatC"
                     /locus_tag="IVD66_000432"
     CDS             complement(35829..36134)
                     /gene="gatC"
                     /locus_tag="IVD66_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HAP6144680.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(36240..38276)
                     /gene="ligA"
                     /locus_tag="IVD66_000433"
     CDS             complement(36240..38276)
                     /gene="ligA"
                     /locus_tag="IVD66_000433"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HAP6144681.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(38293..40527)
                     /gene="pcrA"
                     /locus_tag="IVD66_000434"
     CDS             complement(38293..40527)
                     /gene="pcrA"
                     /locus_tag="IVD66_000434"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HAP6144682.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            40682..42241
                     /locus_tag="IVD66_000435"
     CDS             40682..42241
                     /locus_tag="IVD66_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HAP6144683.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVVGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(42352..44283)
                     /locus_tag="IVD66_000436"
     CDS             complement(42352..44283)
                     /locus_tag="IVD66_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAP6144684.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(44301..45215)
                     /gene="pfkB"
                     /locus_tag="IVD66_000437"
     CDS             complement(44301..45215)
                     /gene="pfkB"
                     /locus_tag="IVD66_000437"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAP6144685.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(45212..45964)
                     /locus_tag="IVD66_000438"
     CDS             complement(45212..45964)
                     /locus_tag="IVD66_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP6144686.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(46123..46332)
                     /locus_tag="IVD66_000439"
     CDS             complement(46123..46332)
                     /locus_tag="IVD66_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144687.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(46343..47671)
                     /locus_tag="IVD66_000440"
     CDS             complement(46343..47671)
                     /locus_tag="IVD66_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144688.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            complement(48036..48623)
                     /locus_tag="IVD66_000441"
     CDS             complement(48036..48623)
                     /locus_tag="IVD66_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HAP6144689.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(48706..49956)
                     /gene="clpX"
                     /locus_tag="IVD66_000442"
     CDS             complement(48706..49956)
                     /gene="clpX"
                     /locus_tag="IVD66_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HAP6144690.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(50203..51492)
                     /locus_tag="IVD66_000443"
     CDS             complement(50203..51492)
                     /locus_tag="IVD66_000443"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HAP6144691.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(51646..52578)
                     /locus_tag="IVD66_000444"
     CDS             complement(51646..52578)
                     /locus_tag="IVD66_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144692.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(52735..53394)
                     /locus_tag="IVD66_000445"
     CDS             complement(52735..53394)
                     /locus_tag="IVD66_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAP6144693.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(53397..54422)
                     /gene="sppA"
                     /locus_tag="IVD66_000446"
     CDS             complement(53397..54422)
                     /gene="sppA"
                     /locus_tag="IVD66_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAP6144694.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(54435..54725)
                     /locus_tag="IVD66_000447"
     CDS             complement(54435..54725)
                     /locus_tag="IVD66_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144695.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            55134..56939
                     /gene="glmS"
                     /locus_tag="IVD66_000448"
     CDS             55134..56939
                     /gene="glmS"
                     /locus_tag="IVD66_000448"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HAP6144696.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(57011..58366)
                     /locus_tag="IVD66_000449"
     CDS             complement(57011..58366)
                     /locus_tag="IVD66_000449"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HAP6144697.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(58390..59559)
                     /locus_tag="IVD66_000450"
     CDS             complement(58390..59559)
                     /locus_tag="IVD66_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144698.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(59556..60443)
                     /locus_tag="IVD66_000451"
     CDS             complement(59556..60443)
                     /locus_tag="IVD66_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HAP6144699.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(60632..64324)
                     /gene="nifJ"
                     /locus_tag="IVD66_000452"
     CDS             complement(60632..64324)
                     /gene="nifJ"
                     /locus_tag="IVD66_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HAP6144700.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            64523..65044
                     /locus_tag="IVD66_000453"
     CDS             64523..65044
                     /locus_tag="IVD66_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAP6144701.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(65743..66300)
                     /locus_tag="IVD66_000454"
     CDS             complement(65743..66300)
                     /locus_tag="IVD66_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144702.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(66479..67090)
                     /locus_tag="IVD66_000455"
     CDS             complement(66479..67090)
                     /locus_tag="IVD66_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144703.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSARYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(67203..67460)
                     /locus_tag="IVD66_000456"
     CDS             complement(67203..67460)
                     /locus_tag="IVD66_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144704.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(68057..68335)
                     /locus_tag="IVD66_000457"
     CDS             complement(68057..68335)
                     /locus_tag="IVD66_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144705.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(68369..68620)
                     /locus_tag="IVD66_000458"
     CDS             complement(68369..68620)
                     /locus_tag="IVD66_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144706.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT        19328 a        14927 c        12143 g        22695 t
ORIGIN      
        1 aaaaacaaag tctttatttc tattatttac ctgtaaccgc aaagtagttg ccatcgggat
       61 cagcaaagtt aaagacatat tcttctccaa gctgtaccat atcacctaat gtgactgatt
      121 gcgtctgcat ttttttatat agtccaaaga tatctttact gtaaaacatc aaagatgggg
      181 cactagtagc tgtgccaggt gaatgggact caacaaatgc tcgatcatat aacagaaatg
      241 aggtttgact gtcctcaact cctacttcaa ttataagcgt cccatccatt tcttgacgat
      301 ctttttccgc aaagccaact gctctccaaa acgttgcatt tttttctaca tcgtccacat
      361 aaagcatgat ttttatttca ttcgtaaaca tctgtttcct cctaaacgat ctgttctaac
      421 attctcaact ttgtcagttt accataggaa aatgggaaaa tctacgaaag ctctcaacag
      481 aatcgtccta cttaaatacg cttttcttta ataataaata agttggttgt ttttgttatt
      541 tgcgctttca cttttcggaa taaataatgt gtatttatat ggaataaata aaaaaagagg
      601 tcgtgactaa aaacaagtca caacctctgg taaacggtgt tctcctgaca actcctcggt
      661 cacaagacac aatattcaac aaacatgaga agctattttt tgaaattgct ctttgtgact
      721 cagagtgaaa cggcaggctc acgacctctt tcttaaacgg tgttcaaaag cttgcatctg
      781 cggtaataag ctcaaccaaa cgtaaaatat gaggaactat ttttgtttgg ctgttcttat
      841 tacttgatgc agggcagctt tttcacaacc tcttattcac ggtgtttcag aagtagcttc
      901 tcggaaataa gccgaaattt cacaaaaatt tgagaaacta tttttaggaa acttcttctt
      961 atttcttaaa gctgaccact tctatcacaa cctctttttg actatgcatt cacatcgatc
     1021 actttagaat catcattgat gacatcgcga tctaaatctt tgatgcgtgc acttgtcacg
     1081 ataccagcta ccatgctacc gctgacgttt actgctgtac gtgccatatc gattaatggt
     1141 tcaacagaga taactaaccc aacgattgct actggcaagt tcattgcccc taaaacgatc
     1201 agtgaagcaa atgttgcgcc cccaccgact ccagctacac caaaagaact gattgttaca
     1261 attgccacaa gcatcaaaat aaattccaaa ctaaagacat tcactccagc tgctggtgcg
     1321 acgatcgttg ccaacatagc tggataaacg ccagcacagc cgttttgtcc aatagacaaa
     1381 ccaaaacttg ctgagaaatt agctgttgca tcatctactc ctaaagcttt tgtctgagtc
     1441 tcgatattca atggcaaagc tccagcactt gaacgtgaag taaacgcaaa gctcaatacc
     1501 ggaaaggctt ttttgaaata gttgattgga ttgacttttg caccaatcaa aatcagtgag
     1561 tggacaatca aaacagcaag caatgctacg taagaagcaa cgacaaattt acctaaattg
     1621 acgatagctg caaaatcact tgttgccaaa acgtttgtca tcaaagcaaa tactccataa
     1681 ggtgtcaaac gcaaaacaag cgtcacgatc cgcataatga ttttatacag actgtcgact
     1741 aaatctgaaa agaatgctgc ttcttttggc gcttttcttt tcacgcctag ataagcgatt
     1801 ccgacaaatg ccgcgaaaat aacgactcca atcgtacttg ttgcacgact acctgctaaa
     1861 tcagcaaaaa cgtttttagg gataaaggat aaaatctgct gtggaatcga taagttttca
     1921 actgtttcct gacgtgttgc cagttcagag attcgtgctg tttctgcagc tccttgtgtg
     1981 aatttagctc cttggagtcc gaacagcatt gttgaaccaa ttccgatcaa tgctgcaata
     2041 gctgttgttc caagtaaaga agtcaataca gtcgcactaa ttttccctag cttttcagaa
     2101 actttcattt ttgtgaatgc accaatgatc gaaataaaca ctaaaggcat aactagcatt
     2161 tgcaagaatg atacatatcc ttgacctaca atcccgatcc attccattga ttgagtaacg
     2221 actttgtcgt ctacaccaaa gatcaattga agcagaccgc caaagacgat accaactcct
     2281 aatgctgtaa agacgcgtgt tgaaaatttt gtatggcgct tttgcatacg atagaacaca
     2341 tataataatg ccgcaaaaac tagaaccact aaaactgtga tgagtgttgt catttttctc
     2401 ctcctcatat tattaatgac aagtccatcg aaggaagtaa aggttcccga gaatgattct
     2461 tcaaccatcc tcctgaaaaa atttttttca gtgactttta tattttagac gatttttatc
     2521 gaaatgacat tctttttgct tacaattagt aataaaaaaa catacctgtg atagctttaa
     2581 tctatcgcag gtatgttttt actgtctatt cttgtttttc tgattgaaaa ttcaatttta
     2641 ccccaggctg atctaaggcg atctctgtca cctcataaga cattcggcgt acgatatcga
     2701 ataacggtgc tactagctcg tccacttctt cttgtgtgac atcattttga ccttcaattt
     2761 tccgattgag gatatgattg atctgactca cacttccaga taaaacatat gtatcaaaca
     2821 ctaaacggaa ctctaagcgt gctcctacga tgctatgttc tttcggatag ttttcgatcg
     2881 tttcttttaa aggcgagaag cctactttca aatctgtttc tacttcttgg ttcggcaatc
     2941 tcatatcata atgaaatgct tctacaactt ctttttgtct tctgatttcc atataatttt
     3001 atcactcctt tatgaaaatt ataacatatc tcctttgaaa ggggatacta ctttttaatg
     3061 atgctctgca aggtaaggat ttcattcaga tttcctacca cataatctgc cgggatctca
     3121 cccagaaaat gatcgatgtc gtaaagacaa gtagcgactc ctgcattttt ccctgcttcg
     3181 atatctaaac gacgatcgcc gatcatcatc gtgtctgttc tttctaaatg aaaagtatcg
     3241 atcaaataat ttaaagatgc tggatcaggt ttacgaggaa agtcctgatc gatccctact
     3301 acttcctcaa tcagatgtgc caatcgatgt tcttttaaca ggccccatgt tgattctgtc
     3361 aaacggtggg tcaggatgaa atgacgaccg ccgttgtctt ttagcatttc cagtacttgt
     3421 ttcgtttctg gaaatggacg ggaaacttcc gtactttctt tttcatatcg gtgaaataat
     3481 tcattaaact ctctggcatt caagtttgat tcattgatca aataactagt agaatacttt
     3541 ttcattttga agtagatttc ttttttgtcc atactgatac caaaatcttt tagtgcttgc
     3601 catgcaccat ctaccattgc gggatacgta tcaaacaatg taccatcaaa gtcccatata
     3661 taatttttca tgttcctttt gttccattcc tttgcttctt ttttctatct ctcactttta
     3721 gataaaggtg ttctttaaag tatttttttg tccagaattg tcaaatcatc tgctaatgta
     3781 tactggattg gttgtgcatt tgggatatcg atcgtatcca tttgatcttc aggaacatct
     3841 tctaaatatt ttgtcagtgc tcggatgcta ttaccatgac ccacaactag taaatcttgc
     3901 cgatctttta gttttggtgc tagatgatct tgccataagg gaatgatccg attcactgtc
     3961 atttccagac tttctccgta tgggatcaaa tgcggatcca agtgatcata tctgcggtca
     4021 aatctatttt ctgcggttaa cggcggaact tccgtatatc ctctgcgcca tgtttttact
     4081 tgatcttttc cgtatatttc tttcatctta tctttgtttt tacccacaag atccccataa
     4141 tgccgttcat ttagacgcca tgtttttatt ataggaagcc ataactgacc catttcttct
     4201 agtgcgactt gtccggtaag aatcgcacgt ttcaaaacag aggtataaac ggcatcgaat
     4261 tgaagtccgg cttcaagcat tttttgaccg gcaactgctg cttgttcttt tcctttttct
     4321 gttaaggcga catctagcca tcctgtccag taattttcaa aatttgcttc gctttcgcca
     4381 tgacgtaata atactaattt cattcttttc tcccttaaac attcgtttcg aattttatac
     4441 cacatgtttt gcatgtcaca cgtattcgtc cttttccttt aggtgcacgc tgcttttgat
     4501 gacaattcgg gcactcaaaa aaagtataac tttttcgatc cattttgact tgctttttgt
     4561 tttttatctg atgatatttt tctttgactc tatcaagata tttcaaataa cgttgattct
     4621 catttagtct ggggtagatt ttttttgata ggaaacgaaa tatcatccat ccgaaaaaga
     4681 cgatgaacaa caattgtccg attctatagg gcaaccaacg acttagcaaa ctaaagacaa
     4741 gcgcagcgat caatagaccg cgattcaact gatcaaattt cgcatatctt ccctgcataa
     4801 gtttgtgata gttctgctga aatcgtatta gcctttctaa ccatgtttgc atcatattat
     4861 ctcctccatc atctaatatt tattatgaca aaaaaatcca aaaagaaaaa gccttaattg
     4921 gccttttcca ttgcaacttg gtgaaggaca ttccgatttc tggtaaagtc aatcacaatc
     4981 actttctttt tatcttctct gttgactact cgaaatgtgt ccgtcaatgg aagaaacagc
     5041 ttcttagatg gtagctgttg catacgtata aaacgatgga tcatcgtaat caattgagga
     5101 aattgaatag acgtgtgaag cagacctgga tattttttca acagctgtgt cgttttgatc
     5161 agattccgtt ttttactgat cactttttaa aagcttttta gaatcttttg ctgacgtcta
     5221 aaaatagaaa aagaattttc gtcatctatt tgataacgca tttgtttttg cagttctgct
     5281 gcagtcagat ggatcttccc atcgtttgta tcgatcatta aaccttctgg aaacagttca
     5341 accactgctc gatcccaaga ttcaagagaa agctcgatat aatcttttac tggtaattcc
     5401 aattctacct taaaaaagtg caaaacagcc gacagccctt ctgcttgata gatttctcct
     5461 aatgttagcc cctctagatg gaactctggt gaaaaatgca gcaatgtttt attttcctgc
     5521 aattgaacat atagaaatgt agatcgctca atcagagtat cttttaaaac aactaaaaaa
     5581 ttcatttttc tccccctttt ttcatcattt ttaaaatagc atattttgaa aagaaagtct
     5641 gatgcttaga gtagaatttc ataaaaattt actatttcat aagtattcac gagaaaaata
     5701 caaacaaaaa agcggaaata acgctcatcc gccttcttgt ttgtgtttat ttcctcttca
     5761 aacgcttgtc tatgattcag acttttctct atcgttattt tcatctaaaa gttcttgcat
     5821 tccgataatt tctcgatatt gatgaatctt agtgatacca atgactttgt ctacatcaat
     5881 actaaaacaa ataccattac ctggaatatc gatgttgatg ccttgaccaa tcgcatccat
     5941 tactttattc gtcaaactat cgggtactaa tgtcaacaca atatcttttt ctggcgaaat
     6001 gtccaaacct aaaaatttcc ctgaatcatg tacaccagaa cctcttccat gtaagatcgt
     6061 tccgcctgct gcacctgctt cttttgaaaa gtcgataaca tcttcgccca ttcctccgtc
     6121 aacgatcgtc acaatcatgt gaagattcaa tgctacaaga tctttcattt gctttccccc
     6181 aatttttgca atctttcttt ttcgattctg tctttttcat cttttcgttt ataaatatat
     6241 cctagtacta aagtggataa tattggtgtc aatgcaatca ttgcaaccac accaaacccg
     6301 tcaatgatcg gatctcttcc ttcaatttgt gcagcgattg ccacgctcat tgataaaata
     6361 aatgtcgaac acatcgggcc cgttgctact ccaccgttat caaaagccat tgctaaaaag
     6421 atcttgtcca cttttcgtcc taaaataaat gctagcccgt atcctgggat caagaaataa
     6481 taaagagaga atccgacgag caaacgccac atagacaatc ctactgctgc gccgatccca
     6541 attgaaatta ccatcagcat gattttcgat cggattctcc cctcgctcaa ttcttcaacc
     6601 tgtttgatca ttacatgaat cgccggctca gcaaacccta ctaagaaccc cattaaaaag
     6661 ccaaggggaa ccagtatata attgtaaggc aatcccgcaa tagcactgcc taaatgctgt
     6721 cctaccggta cataagccat attgactccg tgcaggaaaa ggatcaaccc aatagtcgtt
     6781 atcaagaaac ctttcataat gtcaaagaaa cgctttttgc gcatacgaaa actaatgata
     6841 ttcattaaaa caaataggat tacgataggt gccactgcca aaatgacttc catggtaacg
     6901 atttcgattc catctatcac ttgctgccag aaactcattg gaagatcacc cccaaaatca
     6961 tcacggcaag aatcggccct aacgaagcaa taccgaccat tccaaaactg tcattttcat
     7021 ttttcttttg tttgatcata ctagtcatcc ctccggcaag ggccaagata aatggaacag
     7081 ttactggacc agtagtcact ccccccgaat caaaagcaat cggcataaat tcggaactgg
     7141 tgaaaaatga ggcgatcaaa acgcctatgt agcctatagc catcaattga taataggata
     7201 gcttgaatac gacccgaagc agcgcaaagg ctagaaatac tccagtgccg acgctgacga
     7261 tcccaatcag caacactctg ccaatctctc cgtcagatat atcatatact tgttgtccca
     7321 aaacttgcac ggaaggttca gcaatcgtga tcacgatccc gatagcaaat cccaaactga
     7381 ccaaaacggt caaacttttc tttttgatca tatatttccc tactagatct ccgacttcca
     7441 tcatagaata atctgctcca aacaaaaaga gcgtcattcc gatcatcatg attgccgcac
     7501 caaccagaaa tgaagcgagg tcttctcctt ctaacggtgc aaaaacaaac gttaaaatga
     7561 caatcaggac agtcatcggc aatatagcag caatcacttc tttaaaattt tttagcatgt
     7621 atcctcctcc tttactcttt aagtttacct taaaatgaaa gagttttcga gcacaaactt
     7681 aaaacgttat catttaattt ttctcaacat aaaataacac acgtcccaaa agtatctttt
     7741 tacttggaaa aatgactttg aaggaacgcg cttattgtgt ttttttattt tacagagccg
     7801 atcattcctt gaacgaattg cttttgcaaa acaaaaaata cgatggcagt tggtaaagta
     7861 gcgatgacta atccagccat gatcattcca tagtctggtg tataggaagc acccatagca
     7921 gataaaacaa gcggaaccgt ccgtttatca ggagattgca aagctactaa gggccataaa
     7981 taattgttcc agctactcat gaatgtgatg attgcagccg cggcataggt atttttagcc
     8041 gtcggcatat acactctaaa aaaaatactt agttctttta gaccgtctaa tcgagcggct
     8101 tctactagat cttttggaaa agatttaaca ttttgtcgaa agaagaagat caaaaaagca
     8161 gtgctaacag atggcaggat gacaaccaag aaactgttga ttcccaaaac cgttccgttc
     8221 aattgtgaaa acattcgata taaagggatc atcaatgccg caaaaggaac catcatcgat
     8281 agcagtagaa tattgaaaat taggtctttt cgtttacttt gataaatctc aaatccatat
     8341 cctgccattg acgaaatcag caatgcaaac acagtggtca ccaaagcgat catcgctgaa
     8401 ttccaaaggg aacgagtaaa attcagctca ttggaaaaca aattttgaaa attgatgatc
     8461 aagttactgc caatctttat ttttcccgat gtgatatcca cgggtgtatt cgtcattccc
     8521 aaaaccatcc agacaaaagg gaaaatggaa ataaatgata ggatgcttaa tgctgtatac
     8581 tttaatactg acccaattgt cgaacgaagt tctaatgctt gttttttgac gttggggcgt
     8641 tcgattgttt ctttttctac catatttttc atcgactttc tcctcctact ttcgtttgga
     8701 ttatcgacaa tatcacaata aaggaaacaa taacaaagga aactgctgcc gcatatccaa
     8761 aattaggcgt gaatttataa ctcaaattat agatgtattg agatagggtg gtcgttgcat
     8821 ttgctggtcc cccgccagta atattttgta cttcatcaaa aagctgcaat gtcccgatcg
     8881 tcgaagtaat ggaagtaaac aaaatgattg gttttaaatt tgggatcgtc actttgataa
     8941 actgctgcca tttagaagca ccgtcaatag atgctgcttc ataaatctcc gaatcaatat
     9001 tttgcatgcc tgaaaggaaa aaaatcatat tgtatccagt ccaacgccaa gtgatcgaaa
     9061 gaatgatcag aactctcgcc caaattggat gagtcaacca gccaatcggt gtgtcaatca
     9121 taccaatgcc caacaacaag ttgtttacaa ggccagattg agaaaataga cttttcatga
     9181 tcagagaata actgaccatc gaagtgatac atggaagaaa gatagcggtt cgaaacaacc
     9241 ctttatattt caacttttta tcatttaaaa ggttggaaat aaaaagtgct agaaacaaca
     9301 tgatcggtac ttgtacaagt aaatacagga atgtattaaa aaaagctttt ttaaaagttg
     9361 catctgtcaa catccgctga taattaccta acccgttaaa tgtcatattg acagggggac
     9421 cactttgaaa agacgtgatc aaagccaaaa ccatcggaat aaaaaccatg attgatatca
     9481 aaatgactgg caagattaaa aaagcatgcc cgtttttgaa taaatctttc tgcttcattc
     9541 ttttccctcc aattctatca ttgattatct acatgaaaag acaagaaaga caatatctgt
     9601 aaggcagacg tgatcttttt tgtcttttcg tttgtctgat gaaaaagcga agaaattcac
     9661 ttttttacca ccgatcaatt agccaattgt gcttctactt gtttttgtgt atctgctagt
     9721 accttgtctg tctcttctcc attgatgatt cgatgaagag cttcagctac gactgcttca
     9781 attgcatagg tctcatgtcc gtaattcact tctggtattt cagatgtcca tgttgaaaaa
     9841 tcgtcaaaga tcttttgacc actgtaaaat tcagaagctt cttgataagc ttcttgttca
     9901 ttcgcgctaa gcatcgtaga tactagtccg atttctttcg caagagtgcc catcagttct
     9961 tcattcgaag caaacgttgc ttctaggaaa tctttcgctg aatcttctcc agctactcct
    10021 ttgatcacat accagccagc gccgccaagg ttagaagctt gcgctttttg cagattttct
    10081 ggaagtgcag gtattggtgc aatcttccat tttccagatt ggttttctgc tccttggatc
    10141 gttgaagaat accaagcgcc agttgggcta gaagctactg ctcctgattg tatcgcagtt
    10201 actccagcat tccagtcaga ggtttgttcg actagatctt ctttcaaaag agtggcaaac
    10261 aattcaagac catactttaa agatgcattg tcttggatcg tgactgtctc cccatcttca
    10321 gatgtatacc attctcctgc ctgttgcata atcatcctta ctcgaccaag gtcagaagga
    10381 ttgacttcag cgattttctt tcccgtcttt tctttgacat ctcgcgctac ttgaatatac
    10441 tcgtcccact tcagattctc catatcctct tctgtataac ctgcttctgc catcagatcc
    10501 gtacgataga agtttgctgt tacgcccgaa tcgaaaggaa caccgtatat tttatctcct
    10561 actttgttta ccgcaaattt atacggtgca aaatgatctt cctttacaat agcagacaaa
    10621 ttagcgaatg catctggata agaagtcaaa tagccttgta tcctataatc ttcaatcaag
    10681 acgatattgg gcaatccttc tgtattcccg ctcgctaaag cggtgttcag tttctgaacg
    10741 atatcatcct gagacatcgt aacaacttct atctctgttt cttcgttctc ataaactttt
    10801 tttgcttcat tcactgcttt gatattgaat gtctcatccc acgcccagac agtgactttt
    10861 tcttctttgt ctgctgtact actagcactt ccgcatcctg ttaagaaacc tgatgctgcc
    10921 gctaaacaaa cgactccagc aattaacttt ctgatgttca tttttatccg ctccttttcc
    10981 atccattagt tgtttacgtt tgctacattc atcataccaa aatttgaaaa cggtttcttt
    11041 attattcaga tacttcaaaa atttctccta aaataataaa aaaatacaaa tcaactatga
    11101 caaaaggaat aatcttagca tctagaccaa agatcgaaat ggtgaggttt ctttaaaata
    11161 aaaatatcct tgcattttct cctagaaata agtattttta aattacaaga ctattcttaa
    11221 ggcgggtaaa aaaatgccaa tacgcgtaat tcttatcgat gatgaacaga cgattttaga
    11281 tggaatgaaa cagttgatca attggtctga gcacgggttt caattaatag ggactttttc
    11341 cagtccgctg aaagcgcttg atttttcttt ggtacatgca atcgatatcg tggtcacaga
    11401 tgtaatgatg cctgaattaa atggaatcga attatcgcgg ctattaaaac agcaacaacc
    11461 tgaaacacag atccttatcc tctctagcta tgatgaattt gatatggtta aagattcttt
    11521 taaagaaggc gtcgctgatt atcttttaaa gcctcgattg agtcctgatt tttttctaaa
    11581 ttccttaact gccgtttcac aaaaaatcaa aaaaaagccc aacaaaagcc caatcaccaa
    11641 tcgttatgag cagatctgcg agaatctttc acagcagatt gctggacaaa ctcgtccatt
    11701 gcttgaccct cttctttttg aacacacctt gtttttctgt tatataccga aaaacggcca
    11761 ttcagttcaa aacaaggctc taaacaaaaa cagtcgatca cccattcatt gatggatagc
    11821 gacgattcgt ttactattta tcctgtttct accttttcgg aagaatccgg ctatgtaatc
    11881 aatactgatt ccaaagatac acttaggaag tttgttcaaa agtttcgtca agaagttttt
    11941 ccaggtgatt tttttgttgt ttctgattct tttgcaatcc aagatatcaa tgaaatattc
    12001 caagagatca gaaattgcac caaaggacaa cgtttctatc ataagggaaa gaaccttgct
    12061 tatcagcatg aacttcttcc gttattaacc aaccacgagc agcaagcaag tagttattta
    12121 acaaaaatcg ttcataaaga ctacgcttta gctgtcaaag aacttgagaa tttcttcacg
    12181 acgatattgg aacagcctat tgatccagct tatttgaaac atgaggcaat caatcgtttc
    12241 tatgcattac tcaacgcttt ggctgacgag catgttggga atgaagaact ttctttgctc
    12301 aagatcgccc ttccttcttt attagccgat gctgagtatt tcgaagattt ttctattctt
    12361 gtcaaagaaa cacttgagaa actcacccac ttttctgcaa atgcaaaaaa agacaatttc
    12421 gatatcttga ctttgatcta cgagttcgtc caggaaaatt atgagaaaga aatcaattta
    12481 caacttttat ccgaaaaata tcatttttca tatagctatc tctcagccat ctttactgaa
    12541 aaatttggta tcaacttttc aaaatatcta aaaaaagtcc gtatcagtaa agccaagctc
    12601 tttttgacgg aaacacggct tactttgacg gaaatctgtg agaaagtcgg ctataccgaa
    12661 ctgggttatt tctccagagt ttttaaagaa gagacaggaa tgacaccttc tcaataccgt
    12721 aaaggaactt ttgtaaaatg agaaaaaaaa tcaaagagca tgaactcttt gccaaacttc
    12781 tgttcatttt gttcatcggt ctttttctgc aagccatcgt catttctttg tttatttatc
    12841 atcgatcaag ggatgcctat atccagctgt tcaatcaatc gaatgatgtg gtactaaaaa
    12901 agattcaatc tgaatttgaa agtttgaatg atacaatcga gaatacatta gccgcttttg
    12961 attctaatcc agctgtcaaa agctattttt ccaatgatcc agcccaacat atggaacagc
    13021 ttcagcaact aagaacaatc caaaaaatga atgactctct ttcaaaaatc catccaatga
    13081 tcgattacga tgtattgatc tttggagaaa atggaagaac ttttgtcgga aacgacatgc
    13141 tcactgccgt atctgccgat tctttttttc aatctgcgat tgctcagaga gtgaatgaac
    13201 gtgctgctga tacacaaatg ctttttgcac accacggatt gactcttcgc gataagaaag
    13261 cacccagcgt cttctttgtc aaaaaactga aaaatacatt gaatcacgtt tacggatatg
    13321 ctgttttatc gatctcatcc aagcaactag cgaatctttt tcaatctgta gtaaatcctg
    13381 agatatcgaa gatctccttc atgaacgaag aacagacgat catcgcatca aatgaagaaa
    13441 atacaattgg gagccgatca atgattttca aaaaactaac agtaggtgaa acaacgattt
    13501 caaatggaca gcagttgacc cgtcttcctc tgtaccgcca ggattgtaca ttactcagtc
    13561 aagtcgatct tcattcttta tctaaccaaa tgggcgtgat ttttccgatt attttgtata
    13621 atatcgtgac acttgctttt gctggctcat tggtatttat gtatttggat cgacacacaa
    13681 aatcgatcta ccgcttgatt gattcgctaa aacggctaga ggaagatggc ttaaaagcta
    13741 ctgttcctgt acaaggaagc catgaagtcc aattgctagg gaatacgatc aatcaattgc
    13801 taagtaatgc tcagcatcat tatgaacaga cgatccaaga cgaaaagaag aaacgttcgc
    13861 ttgaaatcca aactatgcaa gcacagatac agccccattt tatttataat acgctgacta
    13921 gcttgaaatt tttgatttgg cagaaaaaaa cagatgaagc agttcaagga atcgacagtt
    13981 tcattacttt actaagaagt acgattggga aaaaagaaga agtgattcca gtcaaggaag
    14041 aaatcaaaag cgtacaaagt tacatcgatc ttttgagtat gcgatatggc gaaagaatct
    14101 cggctaaaat aatgattcct gatgaactgc agtcattatc tatgccgaat atgatccttc
    14161 aaccaattat cgaaaacgcc tatcttcatg cttttcacaa taaaacgcaa ggattcatca
    14221 cggtgtacgg caaaacaaaa aatcagcttc ttttattcga agtgattgat aacggcgatg
    14281 gcttcgatac tgaaaatacc aaacaaaaaa atgatcattt ttcaggaatc ggcatcagcc
    14341 atgtagatga gcggatacgc ctaatgtatg gcgatgcata tggcttaacg atccaatcag
    14401 tgattgggac aggaacgact gtaacgattt gtctaccgct tcttcctaaa aatcaatcag
    14461 aatatcaaaa ataaagaata gccaagcgct gattttttta ttttaagtta aataaatcaa
    14521 tcagtattct tgactttcat ctacgcgtct cttctactgt cagcactgga taacagccca
    14581 atatttgact ttctcctccg agcatcttga tttcttggag cgcattctct actaatgtca
    14641 ttggacggtc caacaacaaa tcgatcacga aaaaatattc tcccaagcta gttttcaatg
    14701 gtcgggattc aatcttactt aagttgattt cccgccagcc aaaagctgcc agcattttat
    14761 gaagcatccc tggccgatta gcaggtagtg tcaagatgac actcattttt actggagctg
    14821 actgctggct ggtcatcttt cggtcaccga cgatccaaaa acgtgtctgg ttcaactcat
    14881 tatcttggat attctcagct aagatctcca atccaacatg ctgtgctgtt tctaatgaag
    14941 caatcgctgc tgcgtcttct ttcggatgtt ctgctacata cattgctgca gcagttgttg
    15001 attctgttgc tactaaagga acattaggat aatgcgtttc taaaaactgt tgtgattgtg
    15061 ctagtgcttg tggatgtgaa aggatttttg taatctttgt tgctggattg cctaaaagct
    15121 gctgcttgat aggaagaacg atttcacttt taacttcgac ttctggatgt ttggaaagaa
    15181 gatcgattgt gtgatgaaca gctccttcca atgaattctc tacaggaacg acagccagat
    15241 cgacttgttt gcgaaacaaa gcgcgcaaac aaacagggat ggaagcatac gcagtcaatt
    15301 gttctgtagg aaatagctga caagccgcct gataagtgaa tgaactttct ggccctagat
    15361 agctgacgtt catatgcttt tgatcctttc tataatggta tcgatgatct tttctggtgt
    15421 ttgattggtc gtgttgattc gatgtgtcgc actttcttca taccaagaaa gtcgttgtgc
    15481 caataatgct tttatttctt ctcttgtttt tccaagagct aaaggtcgaa tagacgtttc
    15541 atcttgttgg atacgatcaa ctagacagtc cgcttctgcc tctaagtaaa gaacaatcgg
    15601 ctgtgttttt aaaaaacgcc gattttctgc actttggaca atccctccac cagtcgcgat
    15661 aattttgtct tcatttgaca gctttcttaa aatatctgac tccacttttc gaaagctttt
    15721 ttcaccgtaa tagtgaaaat attcggcaat cgacaattgg atatgttcct caatctttgt
    15781 atctaaatct acatactctt tttgtaaaca ttgagctaac cctttaccga ttgttgtttt
    15841 tccagcgccc atgaaaccaa tcagcaaaat gctagccatg agcttctcct cctgacacaa
    15901 gttctgctaa atcgtcaaaa aatgccggat aagagattga aacagcttca gctccttcta
    15961 gttcgcaagg tccatcagct atcaaagcag ctacttgcag catcataccg attcgatgat
    16021 cgcctctgct ggacactttt gcgccatgca gaggtgtcgg cccatggatg atcagaccgt
    16081 ctgctgtcgc ttttatcttt gctcccattt tctgtaattc ttctgccacc gcatcaattc
    16141 tgttggtttc ttttactttt aattcttctg cgtctttgat gatcgtgatt ccttctgctt
    16201 gagtagccac taaagctaga atgggcaatt catcaatcag acgcggaatg atttctccac
    16261 caatcgttgc tttcttcaaa tgactcgtct tgacacttaa atcagccgat tggttctgtt
    16321 cattgtgatt cgtctgggta atcgctgcgc ccatctcctc caacacatct aagataccag
    16381 ttcttgttgg attgaccccg acatttttta acaacagttg gctttccgga acaagaagtc
    16441 ctgctgctag aaagaaagca gctgatgaaa tatcacctgg aacagttatc tgttgaccag
    16501 ttaatttttg cggtccggtc actatgatcg ttttatcttc cactgtgatc cttccgccaa
    16561 attgacgaat catttcttcc gtatggttac gggaacgttc tttttcaacg attacggatg
    16621 tgccttctgc ttgtaatgcc gcaaacagca aagcagattt gacttgcgca ctggctacag
    16681 gcatattgta tcggataggt gataaagagc gggttcctgt cacagtgatt ggtagatact
    16741 ggtcattttc ttctccttgc aagtcagcgc ccatctcgcg taaaggttcc atcactcgcc
    16801 ccattggacg tttagacaac gaagcatccc cgaacagagt agtcgtaaaa ggctgtccag
    16861 ccaaaatacc catcaataaa cgtatggtcg taccggagtt tcccatgtca attgattcgg
    16921 ttggttggac aaatgagtgg ctaccgcgac catgaatctt gatcacctct tcctcttctt
    16981 cgatctcgac acctaattgt tggaaggcat gtaaagtact cagacaatct tctgcgcgca
    17041 aaaaattttg tatagtcgtc gttccttcag caattgctcc aaacatgatg ctgcgatggg
    17101 aaattgattt atctgctggt atcctaacag tccctcttaa tccatgtatt tgttgtaata
    17161 attgcattta tccagcctcc tatttgatcc agcaatgata actggtatta gacataatga
    17221 ttctttttgc ttgtaacaaa tcctgttggt ttttaaaact gatttgcagt attcctaaaa
    17281 tatcttccct ggtctcttgg atcttcaaat taatcaaaga aactcccgct tttccgatca
    17341 gtccagttac ttctgcaata acgccaggtt catctggcac atcgataaat aaatcaaaaa
    17401 aggcaggaat cgcgccttgc ttatggacag gcaactggtc tcgactttct tttgcccgat
    17461 tgaaaaaaga aaagatttcc gattggttct cagtcatgat ccattctgct atttgtgtca
    17521 tttcttgttg ccaatctgcc aatcgttcca ataatatctg cttattgctc aacaaaatat
    17581 ctgtccacat gacaggatct gaggaagcga tcctagtgat atctcgaaag cctcctgctg
    17641 ccagttgttt ggctcgcgga tactcttgat tgaattgttc tgcctgattg actaagccag
    17701 ctgccagaat atgtggaaaa tgacttagca ttcctgttat acggtcatgt tctcttgctg
    17761 taagagttac atattttgct ttggttccgc aaaatagttc ttgcagtttt tcaacatctt
    17821 ttttcgtctt ttccaaaggt gtaaagatgt aataggcatt ttcaaatagt ttagcatctg
    17881 ctgcctgtat acctgattta tgagaaccag ccattggatg tccaccgaca aaccgaagat
    17941 ttttctgctc agcggatgtc acgacttgct gcttcgtact gctgacatcc gtaatgatga
    18001 cgtgatcaga caagttgatt ctttcaagga catcaagata agctaaggtt gtacggacgg
    18061 gaacggctaa taagataacg tctgcttgtt ctgcacctgt ttcaaaatca cttgcaacgt
    18121 aatcaacgat ctgctgttct actgcttgct cacgggtttt tgactgacta tcccaaccaa
    18181 ctactatcag ttctggattg gtctgacgaa tacaaagtgc catagaagca ccaatcagtc
    18241 caagccccac gataaaaaca tgttgtgcca tcttatttgc ccccttttta gtaatgtttc
    18301 aagtagtcac ggtactcctt cactgcagct ttcaactcaa caagcgaatc acttgggaat
    18361 tttgacaata gctctgtcgc taccacagtg gctacaacat tttccgcaac gacgctagct
    18421 gcaggaactg ctgtactatc cgaacgttct acacttgctt tgtaaggttc ttttgtatcg
    18481 atatcaacac tttgaagtgg cttgtacaat gtaggaatgg gtttcatgac cccgcgaatg
    18541 acaagtggtt cgccattggt cattccgcct tcgaagccgc ctagattatt ggtacgtcgg
    18601 aaatagcctc tttcttcttc ccataggatc tcatccatca cttctgagcc tggtaatgaa
    18661 ccagaagtga atccgacccc aaattctacg cctttaaagg cattgatact aaccacagct
    18721 tgtgcgattt tggcatctag cttcgtgtcc cattgtacgt agcttcctaa tccagctgga
    18781 acgcctccaa cgagcacttc tacaattcct ccgatcgtat ctccattttt ctttgtctga
    18841 tcgatcaaat cttttattct ttgctcaact gctggatcaa caactcgtac ttctgacgct
    18901 tcagaaattt ctttgatttc ttgaatcgag atatttccag gtatttctgc ttggattcca
    18961 ccaagacaaa tcacgtgtcc tgctacgatg atgtcaagtt cttccagaat tttcttggca
    19021 attgcgccga ttgctacacg catggtcgtc tctcttgcag aggaccgttc aagcacattc
    19081 cgaagatctc gatgatggta tttcataccg cctaccaaat ccgcgtgtcc tggacgcgga
    19141 cgtgcaactc gccgcagtga ttggtctttt tcaggcactt ctgctacaga catgacagtt
    19201 gtccaatttt tccaatcttt attttctacc actaaagtga caggtgaacc aattgttttg
    19261 ccgtgacgga tgccagacgt gatccgaaca cgatcttttt cgatcttcat ccttcctcct
    19321 ctgccgtaac cagcttgtct gcgagcgagt tcgtgattga tttcttcttc tgacagaggt
    19381 aatcctgctg gtagtccttc aataatggct gttaattctg gtccatggga ttctcccgca
    19441 gtcatataac gcatcttaca gtcctcctaa gtaatctttg aatgtctctg tgggaacagg
    19501 aacgattttt gcttgcccaa tcttttctag caagatgata ttcaattggc ttcctcttgc
    19561 tttcttatca tgggttatcg cgtggaataa ttcatctgga tgacttagat cgtacgtaat
    19621 cggcagatgg aatttttgaa gtatcctttc taaagcagct gtcgatccag ttggagacaa
    19681 gccgattttt tctgcatgag aagtgatggc taccattcca atagctactc cttctccatg
    19741 actgactacc ccatatcctg ctgtattttc aattgcatgg ccaattgtat gaccaaaatt
    19801 taaaataagt cgatttcctt ggtcaaagac atcttcttcc actacttttc gtttgatttc
    19861 caacgtagca gtaatgattg gaacagcatg ttccagaaga tctttttcgt ctttcagctc
    19921 gttcagctgt ttccaaagcg ttgcatctgc tatagctgct gatttgatga tttcagcgat
    19981 tccttctcgt aaacgacgta ccggcaaagt ttttagaacc tcaggatcaa tcaatacacc
    20041 agctggctgg ctaaatgttc cgacaaggtt tttcgctttg tttgtattga ctgctgtctt
    20101 cccgccaata ctagaatcta cttgtgcaag tagcgtagtc ggaatttgaa cgaaatggat
    20161 cccacgcatg aacgtcgagg ccacgaatgc tgctagatca cccaccattc ctccaccaag
    20221 tgcaagtatc ccatcgctgc gggtaaaatc attatctgct aaaaaatcgt ataactcagc
    20281 tgcttgttct aaagatttac tggtctcacc cgccggtacg attgaaagga ctggttcaaa
    20341 attagcttgt ctcaattgga acatgatttt ttctgcatat agtggagcaa cgtttgtatc
    20401 agtgatcaca gctacttttt gaggtctcca aatcgtttga agccatgatc cagcctgttc
    20461 tagtgcgcct ttttcaatat gaatatcgta tttttggtta tcaacatgta cagtaagcat
    20521 tcgtttcact tctttctttt aaaaagctgg aattaatcga gtgtctgaat cttttccatt
    20581 gcttctttca tgatcgcaac ttctttcatc atgcgtgagt aagtcttttc attcaacgat
    20641 tggggaccgt ctgaccaagc atttgcagga tcaggatgga tctctacgat catgccatct
    20701 gctccgcttg ccacacccgc acgagccatt ggtggtacaa gttcccaaat tcctgtacca
    20761 tgacttggat caacaatcac agggaaatga gttaattttt tcatcaatgg gacagcactt
    20821 aaatcaaacg tattacgtgt cgctgtttcg taagtccgaa tcccacgttc gataaaaatg
    20881 acaggagatt tgtcttcgac tgcaatgtat tctgcagcat taagccattc attgatcgta
    20941 ccggaaattc cacgtttcaa tccaacaggt ttacctgttt taccgacagc agatagcagt
    21001 ttaaaatttt gcatattacg tgcgccaatc tgtaggatat cgctgtactc agccaccata
    21061 tcgatatgcc cttcatccat cacttcagta atcactttca ttccaaattc atcagccgct
    21121 tgacggatgt atttcaatcc ttcttcttct aaaccttgga aagcatatgg agaagtacgt
    21181 ggtttgaagg caccacctcg cagaattttt gcgcccccgg ctttggccat tcgcgcacat
    21241 tctctgattt ggtctaatcc ttcgatagaa caaggaccag ccatcgtcac gaaactgccg
    21301 tcaccaattt ttactccgtc tacatccacg actgtattgc caggatggaa ttctcgagaa
    21361 gtcaatttgt atgtgtttaa aatacgcaca gcattttcta ctccttcata gcgtgtaaat
    21421 gctccttctt gtaaacttcg cgtatcacct tttagtccaa tcactactcg ttctgttcct
    21481 tgatcgattg agactttgaa tccttctttt tcgatatgat cgacgacttt ttttatttgt
    21541 tcttccgttg cttctttttt cataattact atcattgttt ttcccgcttt cttttgttta
    21601 cttatctatc ttggctgatt ttctctactt tttcaaggtg gttttacatt aattcctact
    21661 aaatgaccgt gtcctgttgt tctcattttc gctccttctt tcctacttat gacccagata
    21721 atcaacaaaa aaagatgtcc ctgtaggaaa ttgcctctac agtgaacatc ttcaacgagc
    21781 cttaaaaagc gctgcaaaaa tataaaatag ccactataga tgaatttctc tacgtggctg
    21841 taagtcgtgt ttaaaaatct ttagccatca tagatacaaa cctggtttgt ttgtacccac
    21901 gaagtcatga atacaaacct atctaaaata gctaaagtaa tacgtattca gttttgtaag
    21961 ttttctagat ttcataaaaa atcgctccaa actgatgtaa gaattgtacc tagtatagac
    22021 ataaaaaaat cgactgtcaa tcatttttat gaaacttttt ttaattttct gatagttaac
    22081 tttgtttttc agaaaaataa caattggttt tattgaagaa aatagtcatg aacaaaagta
    22141 tctgagaact tttttactct cttgttcatg acatatagaa taaagcagct ttgtcttgta
    22201 aactccgttt ttcaaataat aatctaaaga ttgctactga ataataaagc cgatttcatg
    22261 gtcctcttcg ctgctgattc ggtaaggtga ctcaacatcc gctccccagc tattgatacc
    22321 cccgactcct cttacttttg caaaaatcgt aagaaccgtt cgtctttctg gcggtagttc
    22381 ttctatatgt gttgcctgtt ccagttcttc tgctttgaat ggtaaagcgg aaaaagcaaa
    22441 tggcgtatcc tgctgttcaa atcgcaacga aaaatcttct tgatctttat ccgtattatc
    22501 caacgtttga tttcttgtta gttctaccca tttcgtttcc atatgcatgc cgcattcttg
    22561 gggaacaagg tatggggaaa cggggagtcc tgccacttta taaatacctt cgacaccacc
    22621 agccatccga tccggatatg tttcccctga taggccttca tactcaaaaa attttgcttt
    22681 cgttggcata atgaacctta aacccaatgc gggtaattcc ggtaatcctt tttgtccata
    22741 ataatgcata ttgacaagca ttttaccctc tccagcgatt tggtaggaaa ttgtcacttg
    22801 ggtttttggt actgtgttga tttccagtgt aaaaatgatt tcaaccgttt cagcgtattc
    22861 attacttgaa tattgattat ttactggagc aatcggcaaa tcgatctttt tattgtccac
    22921 cagtacttct atttctttga cttttggata caatccggct cctaaccaca taccggattt
    22981 aaatccaaat ccgctacctc tgtcattatc ggtcgttgct cgccaaaaaa ctggaagtgt
    23041 ttcccggtat agccattctt ttccgttttt attgagcgat tccagtccgc ctcttgtata
    23101 agaaaaaata taatgcgtat tccccgattt gacacctaat gtacagtcgc cgaagacgat
    23161 tgcaactttt tccgtatcca tatgactttt atttactgta tttttcataa taatatctta
    23221 cctcctgcat ggcgggtttt tcttgtccat ctgcaaaaac gatcccattc cctgagaatt
    23281 catagtcact tggtttatcg tcaaagtcac cgccatagcg catcacttct ctgcctgtga
    23341 ttggatcagt cacttggatc gcctgatctt taaaatccca tatatagcct ccttggtaca
    23401 tttcataacg atcaagcaac gtcatgtaag aatccattcc acctaacgaa ttccccatgt
    23461 catgcatata ttcacataag atgaacggtt tttccgcttt attttcaagg tagtcaatga
    23521 tctcttctgg tggcgcatac atgcagcttt ttacatctga aatcgaatct tcgaatgctg
    23581 gatttggaaa attcccttca taatggacaa gtcgatcggg gtctactttt ttgaagtaat
    23641 cgttcatttg tcgaatgttt tcttccgcat aagattcatt tccaagagac caaaaaagaa
    23701 tacttggatg gttttttaat gtttcgaaat tcgtttttgc tcgatcaaga acagccgcct
    23761 gccactgagg tactgcacct ggtacgttgt aagaaggctc aaatgcgccc attttttgcc
    23821 atgagccatg ggattcgagg ttcgtttccg ccatcacatg gattcctgct tggtcgcata
    23881 aataatacca agtgatctgg ttggggtaat gagatgtccg tacgccgttg atctttgcat
    23941 tttttatgat agccaaatct ttttccatat cttctatagt gatggcgcgt ccttttttcg
    24001 gatgccactc atgtcgattt accccgttga taatcatccg ttttccattg aagtagatga
    24061 ttttatcttt gatttcgatt ttacgaaaac cgaaggaata gtcaatatac tccgttactc
    24121 ttttttcttc gtctatcgtc tccaattcaa gcttatataa attgggctga aaatgccccc
    24181 acagtgccac attttcaaat ccatcgatgc gaatcgtcat ttgctctttt aacggatatt
    24241 gctgttgata gatttccttc ccatcaggat ctagtatcgc tacattcagc tgactgtttt
    24301 tggctacttg ctcaaaagac aaatctactt caagtttgcc attttgacat ttgtcatcta
    24361 agcgaggttt gatccaaaga tcttctaaat ggttttgtcc tcgagcaact aagaagacat
    24421 ctctgaagat cccaaaaaat cggaaaaagt cctgatcttc caagaatgca gctgtacttc
    24481 ttttgtaaac ctccacagct agaatatttt cttcttccaa ataaggtgtt aaatcaaatt
    24541 cagacggagt gaacgaatct tcggcatacc cgataaaatg accattcaac caaataaaca
    24601 ttgcttgttc tacaccagca aaatgaatcg agatttgttt tccctttaga ccttcttcta
    24661 atcgaaaagt cgtcaaatac gaaccaaccg gattgtcttt agcagctgaa aagatccctt
    24721 ccgcctcttt ctcagggctt gtcgtgaaag ggggacggcg aaatacatgt ccctcccacg
    24781 gatacatcgt attgatgtaa tggatcttgt cataatttgc taattcaata tgactaggaa
    24841 cagtgatttc atcaaaagaa caggcatcaa aatctttttt ataaaatgtt tttggtcgta
    24901 ccgaaggatt tggcgaataa caaaaacgcc atgatccatt taaagactgt ttaagggagg
    24961 atgtggtttc tacttcttcc cttgttgcat aacaaacatg atcgctatgt gcatttgatt
    25021 ggttcactct aaaaacttgt ggatcatcta accattttat atttgctttc atactttttt
    25081 ccttctctct cataactttt tgaaatgaag cagttctgtt tggaaatcac cttgaaaatc
    25141 ggggaagtaa agtccaactg tcatcaattc ggcccccgaa aatatccgct tcgaggtctg
    25201 ttcctgataa agtgcctcat catctaaccc catcagatat acttcatgga acgctggttg
    25261 agctgaagct agtatcctcc ctaaaaacac aatagcttca tcttgtttag gagacacaaa
    25321 catccatgcg gcaatatttt cttcaaaagg actcgccaaa cgataataat ggccatactg
    25381 gatcaccgga cgaatcgttt gataggatat aatttggtct tttacttgct tttcttcttc
    25441 aggagacagc tttgtcaaat ccagttcata accaaaaaca gcgctcatag ctgtttctcc
    25501 tcttgttttc aacgaagtag atctgtcggt ctgatgattt ggtacagctg atacatgagc
    25561 tgtgatggac gaaatcggat aagcaaggct tgttccatat tggattttca tacgctccac
    25621 tgcatccgtg ttatcacttg tccatgactg cggcatataa taaataaacc cggcatcaaa
    25681 ccgtccacct ccaccagaac agccttccca taagatttcc ggataatcag ttgtcaaatg
    25741 ttcaagtagt tcataaagcc cgagcatata acgatgcgct acttctcctt gtctctgtgg
    25801 gtcaagggta atcgaataga catctgaaag cgaacggttc atatcccatt tgatgtagtc
    25861 aagaggaatc gtatctaaaa tctttctcat ttgtttctca atcgtctgcc gaacatctaa
    25921 ccttgtaaaa tccagtacat gttgtgatct ggaagcagaa ggcattctac ctggctcctg
    25981 cataagaaaa tcaggatgtg ttcgatacag ttcagaatca accgagatca tttcaggttc
    26041 aaaccataaa ccaaatttca atcctttgct atgagcataa tctgctattt cacgtaatcc
    26101 atttgtcaac ttgccttcat actcgaacca gtctcctaat gaagaattgt ccgcatctct
    26161 ttttccaaac cagccatcat ctaatacgaa catttcgatg cctagctcct ttgcttcatc
    26221 aatgatcgcc ttgatttttt cactattgaa gtcaaagtaa gtggcttccc agttattgac
    26281 cagaatcggc cgttcagcaa attgatgacg acctcttgcg attctttcac gtagcaactc
    26341 atggtggatc tgactcattt tgttcaatcc ctgacttgag taagaaagga tcatttcagg
    26401 tgtttgaaaa gactggcctg cattcaattc ccacgaaaaa cgatggctgt tgatcccacc
    26461 gacgactctc aattgattga tctgatcttt ttcaagttcg aaagaatggt tgccggaata
    26521 aacaaattga agtccgatcg cttctccagt attttctgtc gtatgatgat gaactaaagc
    26581 aataaagtta ttcatatggt gactgctcgt tcctcgacgg ctttcaaata cttttgttcc
    26641 agataaaaca gattgccgtg aaatctgtct ttcattgaca tgtgctcctg gcaaagcaat
    26701 gacttcatca aatcgcctag tatgggcaaa gtctagctgg aaactagccg ctttttctag
    26761 tttgattgtt tctccggttt catttcttat ctttacagat cgtgtgatca ctgctctatc
    26821 agtaaatatg gtatagaaca aatcgaaata aatcgctgtt tctctatcct taagtgaaat
    26881 caccaacgtt tgtgcctctg acttgtccat cacataagtt tgaggcaagc cttcgatctc
    26941 tggcttccca tctgtaatat aatggctgtc atatctcaga tccagtaagt ctgatccatt
    27001 cttgcgctga atgatcgatg cgggcgttcg aaagtccatg ctgccatgag aagagtattc
    27061 ttgcggtagt gtatctttcg acagagaccg gtcaggattt aagggaacat ttcctgaaaa
    27121 tccacgatct cttcggggat aatttttatt gtctttgtac tgcttgactg gtttgccaaa
    27181 ataaatatgc gccaatacat tgctttcttc tatctttatc agataagaaa gaaatgtatt
    27241 tcgtaaatgg aagactcggc tcttttcatc aaataagatg aaatttttat ctgtttttct
    27301 atgcgtaata tccatcattt cactcccaac aaaacggaaa ccgtttactt ttttttataa
    27361 ttcctgtata ctgtttacta aacaattttg tcaataaaaa ttttttattt ttttgaggag
    27421 tgtgtaaaaa tggttggaat tagagatgtc gcacgaaagg caaatgtctc tcctgctaca
    27481 gtttcccgtg tgttgaataa cgatcagacg atccatgtgg ctcagactac tcggcaacgg
    27541 atagtagagg cagctgctgc gttggattat gacatcagta ctcgtaaata tatcaaaaag
    27601 agaatgcctt cgattggtgt gatctctacg atcggcaaag cgagcgaaga acaggatatc
    27661 tattacaaac atttgcgagt agggatggaa gaagaagctc gacgtctgca tttagggatg
    27721 aatcgaatct ataatctatc tgataatcct aaacaatggg aagatctaga tcagttaggt
    27781 gcggtgatcg ttgttgggac tgttacgaaa gaatcgatta ccgccttgtt aaaacaaaac
    27841 atgcaaatag tcgtcgtgga taaccctgac atccagcaag aggtcgatat ggtgtatgca
    27901 gatcttgaac ggatgactaa aaccgtactg gaattgttct tagaaaatgg tcataaaaga
    27961 atagcctata tcgggggata taaagtcgat atggatgaat tcggtgggaa gcagatttct
    28021 ataaatgaaa agaggatgcg tgcctatcag cattttatga tcgatcatca cttagaaaaa
    28081 tatatgtctt atcatctagg tggctggaca gaaaaacaag gtgaggtact tgcgactaat
    28141 ctattagaaa atgaatcccc tcttcctact gccattcttg tcgggagcga tccaatggca
    28201 attggtgtct atcgggcatt gaaacaaaaa aatatccaaa ttggagaaga gattgttgta
    28261 gcaagctttg ataatatcga gacaatcgca aacctctccc ctggcttgac cagtgttcaa
    28321 atcaatgcga aatcaattgg gcaagcagct gttcgaatgg cattggagcg aattgacggt
    28381 atacgggacg aaccaatcat tttgacttat cctgcacgat tgattgttag ggaaagtttt
    28441 atcccaagaa caaaaaggta ttgaaagaga ggttgtgaaa agccgcttcg tttcttcata
    28501 ctcaaaacga aacggctttt tcacaacctc ttacttatac ttattcacaa aatccaatgt
    28561 ctgctggtaa caattttgcg attcttttag cgtgtaatca aattggtatt catgggtaat
    28621 ctcttttttt gtatctgtat aaaacaagga ttgcacgggt acctttaatt ctgtcaaccg
    28681 attttctaat gcttgacctt gctcctggaa tgagtatgca tttccgtcag ttatatacgt
    28741 tggcggaaat tccttagaaa catggtcagc cacactagct tctttcaatt gctcactcgt
    28801 tttccaatct tttgttccaa tcaacgacca cgcaacggtt ttgacgaaaa acttcataaa
    28861 tcgatcatcc gaatgctgct gtgctgttag cttcaaatca acaggtccgc aataagaaat
    28921 ggttcctttc agactatctt ttggaagtag atgtttgatt ttcatttgtt tagcatacgc
    28981 atcattcgtt tgtatagctg catattgcaa tgcgatttgt gaacctgcac tatctccacc
    29041 aaaaaataat tgttccatgt ctagcaattt gtcgtctttt tcttcagcta ataaatcttt
    29101 gatcagttca ttcacttgaa gaacttgatt agggtattct gaatcaggcg ctaattcata
    29161 attcatcgca accactgcga tgttggcgtc tgaaactaat tttgtcgcaa attctttgac
    29221 acccgattta tctccgccga cgaatcctcc accatgtacc caaaatagaa caggaacagg
    29281 ccccttgctg ttttttggat agtagatgtc ataagtattc tctttatact tggactcata
    29341 cgtcaaatct gtttttttcg ccacgttttt ttctgcttga tcgaacgttt ttttatcagt
    29401 gatttgaaca gtatttgaaa acatatggtt gatcaagaat gctccaggtc tgggggaaag
    29461 ctggaaggca agaaagattg caaacgcgat cccaagaatg attccgaaga accatccgat
    29521 aaatttaaga attttctttt tcataaggct ccctcagtag ttagtattaa gcattctgat
    29581 tataccatag tgttatttcc tatcaagctc tcctagatga tttaatgatt ttccccaaac
    29641 ttcttctgca atgcttttga caaaagaaat tttttccatt gttcttcaaa caaaacattt
    29701 tcttcttctg ttgaagcaaa tccacattga ggacttaagc acaaacgatc caaaggcaga
    29761 tatcgtgtcg cttcgtagat ccggtcaatc acttgctggt gctcttccat ttcgccattt
    29821 ttcgttacag tcaaaatcta agacaactaa tttatcttca gagactttct ctaaaagaac
    29881 aaaactccca gcacgttcac tatcgtattc taaataatag gcacggacat tttcttgagt
    29941 aaaataatgg gtctgctacg tcgtcatccc ccctgatgcc gccaaaatcg aataataatt
    30001 tccgcgtcaa acatgtatat ttagtgttga atcatttgag aatatgaaaa taaaaatctt
    30061 tttgatcaat cagttaatca aattgaaata acgaaaaatc tgagacagaa tgacgttcat
    30121 tctgacccag atttgatttt gcacaactca acagtcctta ttggcaaatc gccaaaataa
    30181 tgtagactaa ctaaaaagac taagaaacaa taacaaaagt taacacttct tagtctttct
    30241 ttagcacgtc tatttattaa agattttagg gccttttctc atgtttttac gatcattctt
    30301 aggtgtttcc atttgtttgg atcggcctcc accttgtttc tttttgatca attctttcat
    30361 tttttctttt tggtccattt ttattctcct ttaacgaatg aagcgactaa ttcgatatga
    30421 tgggtttgcg ggaaaagatc tacaggctga actttcttca cggcataacc tgcttctgca
    30481 aataacttag catctcttgc aaaagttgcc ggattacatg agatatagac gattcgttct
    30541 ggtgacattt cgattgctga ttcaataaaa tgatgatcta atccttttcg tggagggtca
    30601 actacgatca cagatggttt gatccctttt tcttgccatt ttttcataac tttttctgct
    30661 tttccgactt cataatgaac attttcgatt ttattattta aagcattgaa ctgtgcatct
    30721 tcaattgctt ctggaataac ttccatccca tacaccttat ccactctgtc tgctaaagac
    30781 aagccaatcg tacctattcc tgaataagcg tcgatcacaa tgtctttttt atctaactcg
    30841 gcaaactcga tggctgtttg gtacagatac tctgcttgtt gagtatttac ttgataaaat
    30901 gactttgctg agattcgata ggtttttcct aatagctgat cttcgatata gtctctgcca
    30961 tataaaactt tttctttgtc tcctaaaatc acatttgttt tttcttcatt gatattttgg
    31021 atgaccgaaa ccacttctgg caattcttca tgaatagctt cagcaatttc cttggattta
    31081 aagaattttt ctttacgagt aactaaaacg accatcattt catgggaata atgaccacga
    31141 cggataatga tgtgacgaag ctgtccttca tttttttctt cattatatcc tcgtacttgg
    31201 aaccgttgca agatatctct gactactttg attgcttgat cgatgacagg atcttggata
    31261 taaaaatctt cgatagggac tagatcatgg ctattctttt tgtaaaaacc ggtggctaac
    31321 tgtccatcga tacggcgaac agggatctgt gctttattac ggtagccgaa tggttctgcc
    31381 attccgaccg ttggaagtac aggaacttct ggcatcttag caatcttcgc cattacatgc
    31441 tctacttgtt tttgtttgaa gacaagctgt tgttcatact tcaaatgggc taaaggtgcg
    31501 atacctatgc gaagtaatgc attgttttct acaggctgac gatcaggtga ttgtgtaata
    31561 aatgtttcga cttttccata tccaaactta ttgcctgctt ttactactag tatttctact
    31621 tcttctccag ggagtgcatt ttcgataaat aatggataac catcgatttt tgctaccccc
    31681 attccttcat aactcaagtc gacgatttcg actgtatatc gttcgttttt ctttactatt
    31741 tgctgttctg tcatattttg ctcctttaag cctatttttc aatcctactg aactctacta
    31801 taaatcagct aattacacaa ctaaaaccgg cactgacctt actacgttca gcaccggctt
    31861 ttgattaatt cttttgatta ggtgtttcgt ctgctatttt tccgtcaccg tcgatatctt
    31921 catccgttaa acgttcgact tcttttacga attctttgct gacaacctct aattcttctt
    31981 catctgtacc tgtgattgct tcatcaggaa tctgatcggt attggcaaag aactcaatgt
    32041 gttgatgaag attttggaaa tgcatcggtg cttccccgcc gtattcacca tctaagttga
    32101 tcattactgg tcgattgata tcatcttctg tttcaacgaa caaactgctt gttttggtat
    32161 agattattct tggatcatcg acatgtcgac cgccattcag catgagtgct gcaatatgca
    32221 agatctcaaa gatatttgct gtcttcacaa tgattaaaga aaacttccca tcatccaatt
    32281 tggcatctgg cgcgatctgt tcgaatcctc caacagagtt cgtcagccct aggaaaaaca
    32341 tcgaagcatt tccgatatat tccccttcat catacttcaa gcgcattttg attggcttta
    32401 ctcgagggag catctctgct cctttcgcaa gataagcaag ataaccaaaa atactcttta
    32461 gttctgatgg aacttcataa gtcaattctg tcaaatagcc acctgcagcg atattgatga
    32521 agtaactgtt atcagaaagg ccgatgtcca tttttacggt ttggtgtttt tttatcactt
    32581 ctgctgctgc tttaatatta tctctaggaa tttttaatgc tcgagcatag tcgttcgttg
    32641 taccagctgg gatgatggcc attttaggac ggtgttcaag cggagcgatt ccattaacca
    32701 cttcgttgat tgtgccatcg ccaccagctg ccactactag atcaaaacct agttctgcga
    32761 ctctacatgc ttcattcttg gctgaatctg gttctggtgt agttgcatag gcgctggctt
    32821 caaatcctgc ttcttctaat gcctgtagga tatccgccaa attttttttc aataattctt
    32881 ttcccgaggt ggggttataa attacgcgtg cttttttcat tttcagcctc tatcgtttcg
    32941 ctaattcatc tttaagtagc ttattcacga caccaggatt tgcttgtcct ttagttgctt
    33001 tcatgatttg accgactagg aagccaaccg cacgatcttt tccatttttg aaatcatcga
    33061 cagattgttg gttgttatcc aaaatttcat taatgattgg cagtagtttg ttcggatcag
    33121 ataattgcac ccaaccattt ttttcaacta cttcttgggc ttctccgcca tttgtgatca
    33181 attcacggaa gacttttttg gcgatttttg agctgatcgt tccatcggcg atcaaacgaa
    33241 tcattcctgc taagttctca ggtgtcaatt ttgtctcagc taattccagt ttctcactgt
    33301 tcaagtaagc agaaacttca cccatcaacc agttagatgc ttgcttggca tctgcaccat
    33361 tttccaaaac agcttcaaaa aaatcagaca tttcttttgt aagtgtcaat accattgcgt
    33421 catactctgg aagtccaaac tcacggatat agcgttcgcg acgagaagct ggcatctcag
    33481 gcaaactagc ttttactttt tgaatccatt cgtcatcgat cacgaatttc gggatatcag
    33541 gctctgggaa gtaacgataa tcactagacc cttctttgac acgcatcaaa actgttttat
    33601 tcgttgtttc gtcaaaacgg cgtgtttctt gttggatttc tcctcctgaa agaagaactt
    33661 ttgcttgacg tttttcttca aaagctaaac cttttttcac gaaagataaa gagttcaagt
    33721 ttttcaattc tgctttcgta ccgaactctt cttgtccata agggcgaaga gaaatattgg
    33781 catcacagcg catagagcct tcttccattt tcacatcgct gacttctgta aattggataa
    33841 ttgatcgcaa tgcttctaga taagcgtatg cttcttctgg tgaacgcata tcagcttcag
    33901 aaacgatttc gatcaaaggc gtgccttgtc ggttcaaatc aacgtaagaa taaccgccaa
    33961 taccatgcat gttttttcca gcatcttctt ctaaatggac acgttcgatc cggatttttt
    34021 tctttttacc ttctacttcg atttcgatcc atccgtcatg accgattggt tgatcaaatt
    34081 gggaaatttg atatgctttt ggattatctg ggtaaaagta atttttccgg tcaaaatgag
    34141 tatctttaga gatttcacag tttaatgcca aagctgcttt catcccgaat tccagcgcag
    34201 ctttattcat tactggcagc acgcctggat aaccccagtc gatcacgttt gtattgctgt
    34261 ttggttctgc accaaaatga gctggcgctg gagagaaaat ttttgagttg gtttttaact
    34321 cgacgtggac ttctagtcca atgactgttt caaaattcat tcgtctttcc ctcctaaaat
    34381 agctggttgt tgtttatgga attctgttgc ttgttcaaac gcatatgccg cttgatacat
    34441 cgttttttca tcaaaataat taccgatgat ctgcaatcca actggtaatc cttctgataa
    34501 acctgccggt acagacatac ctggaagtcc agccaagttg acagggatcg ttaagatgtc
    34561 actcatgtac attgtgattg gatcgttaat gttctcaccg attccgaatg caactgttgg
    34621 tgaagatggc ccgatgatca agtcataatc tgcaaagact ttttcaaaat ctcgtttgat
    34681 caatgtacgg acttgtcctg cttttttgaa gtaagcgtca taataacccg cgcttaagga
    34741 gaatgtacct aacatgatac ggcgttttac ttcttcaccg aatccttctg aacgtgagtt
    34801 gacatataca tcatctaatg atttcacatt ttcagagcga taaccgtagc ggataccatc
    34861 gaatcgttgc aaattggaac ttgcttctga tgaggcaatg atataataaa cagccacacc
    34921 gtattttgaa tgaggcaagc tgacttcttc cacaacagca cctaatgaac ggaatgtttc
    34981 tgctgctttc aatacagctt cttttacgcc aggggccaca ccttcgccta agtattcttt
    35041 aggtaaagca atcttcattc ctttgatgtc gcctgtcagt ccctctgcaa aatcaggaac
    35101 tgaaacgcct gaagaagtac cgtctttttc gtcataaccg ctgatagctg tcaatgctaa
    35161 tgcattatct ttcaccgtac gggtcattgg tccgatttgg tcaagagatg aagcaaaggc
    35221 aatcaaacca aaacgtgaga cacggccata agtaggtttc atccctacga tgccgttaaa
    35281 agctgctggt tggcggatac ttcccccagt atcactacct aaagaaactg gaatttgtcc
    35341 agctgcaact gctgctgcag aaccaccaga agagccacca ggtacttttg ttgggtccca
    35401 agcatttttt gttttcttga aataagaagt ttctgtactt ccacccatag caaattcatc
    35461 catgtttagc ttaccaacag ggatcatatc tgcttgatag attttatcca tgaccgttgc
    35521 atcataaatt ggttcaaaat tgtaaaggat cttagatgca gcggttgtca agatatcttt
    35581 tgttacgata ttatccttga taccaattgg aataccagca aggacgttgc tttcatcaat
    35641 ccctttttca tctaaagctt ttgcctgttc caatgctttt tcttcgttca atgtaatgaa
    35701 tgcctcgacc tcaggctctg tttctttgat tcgttcaaat gttgtttttg tcaaatcttg
    35761 tacagtgatt tctttcgata caagcatatg atgcagttct tctagagaac gattgtgtaa
    35821 ttctgtcatt atgcgccagc ctccccatta tcgatgattg cgggtacttt gataaagccg
    35881 tcttctgttt ccggcacatt tttcaataat tcatcgcggt tccatccagc ttgcgcccga
    35941 tcttgtcgca tcacgtttac tgtttcaacc acattcgacg taaatggaac accttccgta
    36001 tctacttctt ccagcatttc aaccatatcg atgattttac ctaattggtc ggtaaaactt
    36061 gcaagttctt catctgcgaa cgcaagtttt gctaatttgg caacgtgttt cacttgttct
    36121 tcactaatcg ccatactacc ccttctttct aaacgagtta aaaactttgc tctctatttt
    36181 aacacaagag tgccgtgtct gaaattgttt attgaaattt gtctgaaaaa actcattttt
    36241 cattcttcta ctgagcgact tttagccaat gcatctgcca tttgatcttc tgtccaaact
    36301 tcgattccta attcttgtgc tttggtcagc ttgctgccag catcttctcc tgctaccacg
    36361 atatccgttt ttttcgatac gctaccagtc actttcccgc caagattttc gatcgtctct
    36421 tttgcttctt cacgagtaaa tcgtgttagt ttaccagtaa ggactactgt tttttcttta
    36481 aaaggagact cgacttcttg caattgggca tttcgaagcc ctttgtattc gaaattgacg
    36541 cctgcttgtt ttaattcatt catcaattca tggacttctt cgttactgaa ataagtgact
    36601 acactgtcgg caatgatatc accgatcgta tcaagcgcaa taatcgactc atagtcactt
    36661 ttactcaatg tttctagatc accgaaatgt tctgctaaaa tttttgctgc tttcgctccg
    36721 acatgtcgga ttcctaaccc gaaaatcaac cgctcgaccg aattatcttt gctgttgtcg
    36781 attgctgtca aaatattatt tgctgatttt tcttttattt tgtccaacgt caataactct
    36841 tcttctgtca atttgtaaag atcagcaaca tctgctacta gttttttatc atacatctgt
    36901 tctagtacgc gcggccccaa cccatcgata ttcatcgcat ttcttgaaac aaagtggttc
    36961 aaaccttctt tcatttgagc agggcattta ggattgatgc accgtaaggc tacttcttca
    37021 tccaaatgga caagttcact tccacaaact ggacaatgtg taggcaattg gtattcttcg
    37081 ctgtctttag gtcgtttatc taacacgact tgcgaaactt ctgggatgat gtctcccgct
    37141 ttataaatca gaactgtatc tttcaagcgg atatccttca acttaatata atcaccgtta
    37201 tgcaggctgg cacggcttac tgtcgttcct gctactcgga ctggtgtcat gatagctgtt
    37261 ggcgttacta cccctgttcg accgactgtc cattcgatgt tttcgattag cgtttcaact
    37321 tcttctggcg gaaacttgta agctgctgcc catctcggtg ctttgatagt aaaaccaagt
    37381 tgatcttgta gcgagaattc attcactttg atgacgattc catcgatttc atagggcaaa
    37441 tccacacgtt tgtcatgata ttcttcaatg tatgaccaca cttcatcaat cgaatgacat
    37501 agacgttttt cccgattcgt gtggaatcca attttttcta gctcttctag cgcatcatac
    37561 tgggtttttg cttgcatagg accgaaatca gctactgtgt ataaaaaagt gtccagattt
    37621 cttttcgctg tgattttaga atctaactga cgcaaagaac cagctgcggc gttccgagga
    37681 ttcgcaaaga tatcttttcc ctctgcttct ctgtcttggt tcaattggac aaatgaccgt
    37741 tttggcatga aacattcgcc tcttacttcg atgttcattg gttcttttaa tttgattggg
    37801 accgaccgga cagtttttag gttttcagtg atgttttctc ctacagttcc atccccgcga
    37861 gtcgcacctc tcacgaaatt tccatcttca taacgcaaag aaacggaaag tccatctatt
    37921 tttagttcac agcaatagtc aactacacgt cccactgctt tttgtacacg ttgatcaaaa
    37981 gctatcagct cttctttgct gaaaacgtcg ttcaaactgt aaagcggaat atcatgagtg
    38041 actttttcaa aaccttctaa tacttttccg cctactcgtt gagtgggaga atcagacgtg
    38101 atcaaatcag gatattgttc ctcgattgct actaattctg cgtattcttt atcataaaca
    38161 tagtcttcca ctgttggttt atcttctacg tagtattcgc gagaccattg gttcagtctt
    38221 gtacgaagtt cttctgctcg tttagcagct tcgtcaatcg tcatttcatg ttccatcatt
    38281 taccctccac tactaagctt tttcaattgg cgcaaaggca gccaaaagac gttttactcc
    38341 ttgacttggg aaagccacat ctagttctag atccttcgac gtcccgctta ctcggacgac
    38401 tgttcctaga ccccattttt tgtgtttgac tttatctcca ggtttccagc tgttattttc
    38461 ccctccagta gcacttttag agggaacaac cgctgtctct ggctgtttat agctatatgc
    38521 tgttttttta gcgaatacag gcgttttttt aggcgtagga cgcatgcctt cgatttccag
    38581 taactcctga tcgatttctt ctacaaaacg agaaggtcgg ttatattgcg tccgtccata
    38641 taatgttctg gagaaagcat ttgttaaata caacgcttct tctgctcgcg tgatccccac
    38701 atatgcgaga cggcgttctt cctccagttc gctttcttcc atcaatgctc gagataaagg
    38761 aaaaaccccc tcttctagac caatcaggaa tacaactgga aattctaatc ctttggctgc
    38821 atgcaaagtc atcaatgtca cttgggaagc atcttcttct aaattgtcaa tgtcggaaac
    38881 aagtgccaga tcatttaaga agaccgttag tttttcttct ggtgcatcag cgtcttcttc
    38941 attttgctgt tcgaattgtt tgtcgaattc ttgtgtgacc gttaaaaatt cctccaagtt
    39001 ttcgatgcgt gcttgtgctt ctaatgtatt ttggattttt aagtcttcta gatatccgct
    39061 acgatccaaa acctctttcg tcaattctgt cactgtcaag tatgggatca tctgagtgac
    39121 ttcttggatc atctctccaa atgcacctaa ttgctgtcct gcttttccac cgatatttgc
    39181 cagatccaca ttttgcgctg cttcaagcag tggccattca tgaagagaag caaaactgcg
    39241 tagtttttcg atagatcctg gtccgatgcc tcgtttgggc gaattaacga tacgctcaaa
    39301 actgattgaa tcttgaggat ttaccagcac attcaaatac gctaaaatat ctttgatttc
    39361 tttacgatcg tagaacttgt gccctccaac cattttataa ggaatatttg ctttcaacag
    39421 agtttcttcc attacacgag attgtgcgtt cgtccggtac aagatggcaa agtcgccgta
    39481 attccgatga ttgcttcgaa tctcttcttg catccggtct acgataaaac gggtttcgtc
    39541 tcgttcatta tctgcacggt agtaagtgat cttgtttcct tctttgtttt ctgtccacaa
    39601 gttttttggt tttcgattgc tattgttttc aatgacttgg tttgctgcgc taaggatgtt
    39661 tttcgtggag cgatagtttt gttctagcaa aattactgca gcatctggat aatctttttc
    39721 aaaatccaag atgttctgca tatctgcacc gcgccagccg taaatacttt gatctgcatc
    39781 tcccacgacg cacaggttcc taaatctacc tgccaataaa ttgactagcg tatactgtgc
    39841 gtgatttgta tcttggtact catctacatg aatataatgg aatttgtttt gataatacgt
    39901 gagtgaatca ggatgttctt caaataatcg aatcgtattc atgatcaggt cgtcaaagtc
    39961 catacattga ttatattgaa gctctttttg gtaagcagca taacattttg ccgcaatctc
    40021 ttcgtaataa ctgccttgca tttttgcaaa atcctgaggg gtctgcaggc tgttttttgc
    40081 ttgagagatt gttcctaata tacttcgagg atcatatttt ttcggatcaa tgttcagttc
    40141 ttttagtatc cgtttcatca aggtcagctg ttcagaagaa tcgatgattg taaagttccg
    40201 gttatacccg ataaaatcaa catctcttct taaaatacgc acacacatcg agtgaaaagt
    40261 cgatacccag acatcttcgc ctccagatgc gagaatcgca ttgacacgtt ctttcatttc
    40321 ttttgcagcc ttattggtaa aagtaatcgc taggatgttc caaggattga cttctttttc
    40381 ctcaatcaaa taggcaatgc ggtgtgtcag cactctcgtc tttccacttc ctgcacctgc
    40441 cattagcagt aatggtccgt cagtgtgaag aacagcttct ttctgacggg ggttcatccc
    40501 gtttaataat tcagctttgg atgacattaa caacatcctt tcttttatca atcttgttaa
    40561 ttatagcatt ttcttggctt tcattaaact agctagttca aaatcatttg tttcttttta
    40621 tggatttttc cttgtcaatt cgttgatttc gcgctaaatt aaaagaaagc gaggcgtttg
    40681 aatggaaaaa aaaggaaaaa tcaagaaatt agataagact cagatatatt ttattctaaa
    40741 aggaatattt gttggactgc tgacaggaat cgtcgttagc ctgtttcgat tatctatcga
    40801 aaagctaagc gatttagttc gaagtatcta tgaaatgagt cgggaacagc cgatttactt
    40861 aattggccta gctatttgct gcatccttgc agcatttttc gtgggttatc tggtcaaaaa
    40921 tgaaccggat atcaagggaa gcgggattcc acaagtagtg ggacagcttc gcggggaatt
    40981 atcaatgaac tggttctctg ttttatggaa aaagttcatt ggcggtgtac tttcagttgg
    41041 tgcgggcctt tttctaggta gagaaggacc ttctatacag cttggcgcat ccattggaca
    41101 aggagctgga caattgtttc ggagtccatc ttcagaagaa aagattttaa tttctagcgg
    41161 tgcaagtagc ggacttgcag cagcattcaa tgctcctatc gcaggattac tctttgtttt
    41221 agaagaaatc catcactcct tttctccact tgtttggctg acatcatttg cttcagcaat
    41281 cactgctaac ttcgtctctc tttacttttt cggcttgaga cctgttttat atctaggtga
    41341 ccttccttct ttgccgttga aatattatgg ttccttagtg atcttaggag tacttctagg
    41401 catcttaggt tttatttatc agaatgtctt gctggctttg ccaaaatttt acaaccgatt
    41461 gcctttacca gcttattttc acgggttcgt tcctttcttg ctgattttgc caattggtta
    41521 tttatggcct agtactctag gcggaggcaa tcaaatcgtt ttagcttttg gacatgcttc
    41581 cttgccaatc attatgatta tcggtttgtt tgttcttcga ttcgtttttt ccatgatttc
    41641 ttacggtggg ggtcttccag gggggatttt ccttccgata ttgacattgg gggctttaat
    41701 cggtagcttt tatggaaaca ttatggttga tttcgggatg gatccaatct acatcaagga
    41761 ttttgtcgtt attgccatgg ctggttattt cacagcgatt ggaaaagcac cgctgacagc
    41821 aattatttta gtgacagaaa tggttggctc tcttaatcat ctgatgcctt taggattggc
    41881 tgctcttgtt gcttatatcg tcaatgacct tctcggcggt aatccaattt acgaatcatt
    41941 attggaacgt ctacttggaa atactcagac cgcctcacta aaaggtgcaa ggacaacttt
    42001 tgattttcca gtaacggcag agagttcttt agacggatta atggtacgag acttcaattg
    42061 gcctaaaaat atgctgctaa tctctatacg cagaggaaat caggaaatct tgactcacgg
    42121 tgatacgatc atgaatgtag gagatatttt ggttatcttg actgatgaag caaacttgcc
    42181 aagaatcaag caggaaatcg aggctaaatc ttctatcaca aatttgaagc aatcatttta
    42241 acgaacatgg aaaaactatt ttacaacaac tattcatcta cactacttga ttctatatga
    42301 ttctataaaa aaagaagagg ctgggaaaac ccagcctctt cttttttatt tctatgcttc
    42361 tgctactgca ggagcttttc tcaataaacc ataaatcaca ccagatacga ctgctccgat
    42421 agcaataaac accaaataca tgaccgggtg actcagtaag aatacaacga aaatcccgcc
    42481 gtgaggagcc agtaatttga ttccgaaagc tccgactaat ccgccagtta aagcagaacc
    42541 aataataaaa cttggaatgg cacgaatcgg gtcagctgct gcaaatggaa tcgatccttc
    42601 cgtgacaaac gatagtccca tcacgatgtt cgtcaaacca gcatcttgat ctgttttgct
    42661 gaatttattc ttaaacaaac gtgtagcaac gaaaattgcc aatggaggta ccattcctcc
    42721 agccataaca gaagccatca cgacacttcc gccagttgca acagtcgtag ctaaagttgc
    42781 tgtaccaaac acataagcgg ctttgttgat tggaccgcct aaatctgccg ccatcattcc
    42841 agctaataat gcaccaagta aagcagcatt cgaaccactc atacttgtca agaaaccgtt
    42901 caatgcatca ttgattgctt tcatagggac attgaccagc aacatcaaga aaccagtaat
    42961 cagtaagcca aacactggat aaaagaggat cgttttaatt ccatccaatg attttggtaa
    43021 gttcttgaat aatttacgta aaaatacgat gacataacca gctaagaatc caccaatcag
    43081 tgcacctaag aatcctgcac cgcctgtatt agctaatgca ccagcagcaa atccaacgat
    43141 caaaccaggg cggtcaccga tacttgaagc aataaatcct gctaataccg gcagcatgaa
    43201 accaaatgca gcttgtccga tttggttgaa ccagctagca gcttgattgt aattccctag
    43261 atttgataat tgatcatgtg gcacgccaat aaattggtcg atcatgaaag aaagcgcaat
    43321 agcgattcct ccaccaataa cgaaaggtaa catgtgtgat acgccgttca tcaaatcttt
    43381 gtaaattctt tgtccgatag taccatccgc atttccttct tctgaactgc tttcttttcc
    43441 atcaccatgg aatactggtg cagtaccact aagggctaga ttgatcaact cttctggttt
    43501 acggatacca tcactgacag gacgattgat cagttctttt ccgtcaaagc gattcatctc
    43561 tacttttttg tctgctgcaa cgattacacc ttctgcacgg gcgatgtctt cagcagtcaa
    43621 tcggtttttg attccttctg aaccgttcgt ttcgactttg atctccacac ccatttcttt
    43681 cgcttttttc ttcaaagcat cttctgccat gtaagtgtga gcgatccctg ttggacaagc
    43741 tgtaacggca acaacgaatt ttctttctgg atgagcagaa gcttctgcag cttgtgtttc
    43801 ttgttctgct ttttcttctg cttctttttg ctcttcagct gtttggaaca agtcttggac
    43861 ttcttctggt gtatttgctt cttttaattt tcctacgaaa tctgcatcaa tcagcaatcg
    43921 agatagtgct gctaatgctt gcaaatgtgt gtcgtttgcg ccttctggag ctgcgatcat
    43981 gaaaaacaga taagttggct gtccgtctaa ggcttcataa tctactcctt tttggctttt
    44041 tgcgaataaa actgttgctt ctttaactgc actgtttttc gcgtgaggca tggcgattcc
    44101 atcaccaaga cctgtagaag tttgtgcttc gcgggctaga attccttctt tatatgtttc
    44161 gatatcggaa atccggccgg catcaaacat tttttggacc atttcatcga ttgcgccttt
    44221 tttatcagtc gcttgcaaat ccatgatcat cgcttctttg accattaaat ccttgatatt
    44281 catgattatc ctccttgaaa ctaatcaatt tttgtgattt caacttctgg cagcaactca
    44341 tcaatcaatt cgcgagctgc caagtcatca gaaaaagctg ttgcgcttcc gcaagcaact
    44401 ccccatttaa aggcttcgat tggatctttc gtacggctgt aagccccaat aaagccagca
    44461 atcattgaat cccctgcacc tactgaattt ttcaatgggc gaactaatac attcgtttta
    44521 taagttcctt gttccgtgaa gagcaaagca ccgtctccag ccattgagat cagcacattc
    44581 tgtgcccctt cagctagtaa ttttttccca tacggaatga tttcttctac agattggaag
    44641 gttgtgttgt aaagctcagc taattcgtga ttgtttggtt tgatcaacaa cggtttctta
    44701 acaagtgcat tttttaggtc atcacctgtt gtatcaatca cgaaatctgc acctttttct
    44761 cgaatgatat caatcagttc ttgataaaat ccttttcgca ggctagctgg cgcgcttcct
    44821 gacaatacga cgatatctcc ttgtcctact gttcctaatg cttgcttcaa ctcatcgatt
    44881 tcttcatctg aaatagatgg gcctaagcca ttgatctcag tttcagtgtc tgattttagt
    44941 ttgatattga ttcttgtatc ttcttttacg gttgtgaaca aagactggat ttgttctttt
    45001 tcaagccact tcgaaataaa ttcgccagtg aaccctccta aaaaccctag tgctgtagat
    45061 tgagaatcga tccgtttcaa aatacgggaa acattgatcc cttttcctcc aggtaacttg
    45121 aagtcttcct tcattcggtt caaatcgcct agttttaacc catctacgcg tacgatataa
    45181 tcaattgatg gattaagtgt tactgtgtaa atcattgtat tgcctcctta attgttgtct
    45241 tttcacggaa ttcattaacg aattctaatg gacaacgctc ggttatgatc gtggctgctt
    45301 ccaaaggtgc aacagaggtg aaggacaact ggttgaattt ggtatgatca atcaatacaa
    45361 atgtctcttc ggaatttttc atggctaaac gtttaacagc tgcctcttct ggatccggag
    45421 tcgtgaatcc ttgttcaaga tgggcaccgt tcattcccat aaatgcttta ttaaaatgaa
    45481 aattttttag ttgttctatc gcattagatc ctaaaacagc attagttgcc agctttatcg
    45541 ttccacctaa aataatggta gcaagctcca aatcaactaa atttgccgca tgttgaacgg
    45601 aatttgtcac tactgtgatc tgttttcctt gcagaaaagg aatcatttct aacgtagtag
    45661 agccagcgtc taaataaatg acatcttcgt cattaatggt ttcagctgcc gatttggcga
    45721 tttgctgttt ttcgtgaacg tttttgagtg atttttcact catattctgc tcaaaattca
    45781 ataattgctc tttcttagct ccgccatgaa ctctttctag aaacccacta ttctccagct
    45841 cttgtaaatc acgtcttatc gttgattcag aagcattcaa aaggtttaca agatcttgtg
    45901 atttcacgat tttctgctgt tcaagcaagt ctaggatttt ttgtctgcgt tcctctgtaa
    45961 gcattttcac gatcacctca atacaaataa tagcatattt tttttctact agcaatataa
    46021 atcagtcaaa aacgttcata aaaattataa atcagtcaaa aaaaaataaa aaaccagtca
    46081 gaaagactgg ttttttattt ttttgtctat catcaagccg ttttatcgtt ttttattttc
    46141 gcttcttgtt tttttcatat aaacagaagc aggttttctt tccttatgaa gaagataata
    46201 ataaagtccc atcccgccaa acatgaccaa aaaaccgatg actgatcgaa taggaaaatt
    46261 aggaacaaaa aagagacaga cggataataa tgatgccgga accattattc gataatagag
    46321 ttgtttatcc attttcttca cctcatattt tttgtaaagt aatcaattgt tctaattctc
    46381 ggtaatctaa aaattgcaca cgcagatgct gctcaccttt cttgacatcg aattggatac
    46441 ttcgccgctt tttctttatt cgtttgaagg taacatcaga gagtctatgt ttgatttcct
    46501 ttaacggtaa ttctgacagg gattctgaag gaacatagat tcttaaggat aaaagatact
    46561 cttgatattt ttcatctgtt acctctactt ctagatattc cctaatataa taacaataag
    46621 cttcgattcc attatccaaa gcaacagtcg gatcgataac tttatagcac atcatgcgtg
    46681 atcgattctc gtcaacccaa ggaaaatacg cctgagcatt tagtgttccg cgaacacgcc
    46741 tttctttata atctccttgt tggatatcat aactttttgt tacaaaaaat gaagcattct
    46801 ttttaggaac aggttgcatt tgtgcattct gatactggac agattggatc gtatggtcag
    46861 tgtaaatgta ttcaacgaat ggcggtttca ataaaccgac accattgtcc caagcaagat
    46921 gatcaaaccc aagctggtcc ctaaaatagg attgaaacat ttgattgttt ggcttttgcc
    46981 agttaaaggg gtctcgataa agctggatac atatgacttc gttttctaat tccttcactt
    47041 tttctacttg ttggatgtcg agaaaaatcg gtttagggat gatttgatga taatagcgac
    47101 tataatacat ttcccaacac gaagtgaaac ataaaccttg gtaaaaaaga tcgtatcctg
    47161 gaaattggtt gcaatcgact actacttccc cgttttgttg tttcatttta ggtaaatgtt
    47221 cgatttcatc ctttttctca aacaatagcc gttgagagat ctgttttgta ttgtgataga
    47281 taaactcgct ataagctcgc atataggcga acaccccatg agcaatcatt tttttctgaa
    47341 tgaagtctcg aatcaaaaat tgcttttctt tgaaaacaga gatagacaat acatttttta
    47401 tcaataattg attatcttcc aagcgaaaac tacattcgtt ctcgtcattt cctacaacta
    47461 accaactttc gtctcttacc gatgctagca ttattttttc ttgaagcttt cgaagatcat
    47521 acggatccgc ttgttgtgtg aaagagcgga taaatgttgg ctggatcaac agacgtgtca
    47581 aaatagccca atcgcttatt tcctgttttt tttcttcttc atttaagtct gtgagctgga
    47641 tagtcatcaa taatttatct tcgccaatca ttttctcacc tctttcaaat ctttttataa
    47701 tttaattata accaatgata aagaaaaact aaaactttat gtcttagaaa ccaatttgga
    47761 cgattacatg atagactaag taaaaagaaa caaagaggtg tttacaatgg ggttgaaatt
    47821 tgaacgtaca gataatttag ataaactttt cgaatcattt gctgtcgatc cggaaaaaac
    47881 agttgcacca aaagaagaga tcgatcgatt tctaaaacca cagccacaaa atgaaaagaa
    47941 aaaagacaag aaacaaaagt aagttaagct caaaaaaaga cttaccagcc aaacttttat
    48001 gaaagagttt gactggtaag tcttttttat tctttttatg attcaattgc ttgttcgatt
    48061 gctgcccacg cttcttcttt tccctgtttt gtaacggaag aaaagagaat aaacgtgtca
    48121 ttgcgatcaa aatccaacgc ttttttgatt tcgctctcat gcttgttcca tttaccacga
    48181 gggatcttat ctgccttagt ggcaacaaca attacaggga tatcataata cttcaaaaat
    48241 tgatacatct ggatatcttc ttgagaaggc ttatgacgca aatctactaa agaaacgacc
    48301 gcacgtagct ggtctctagt cgttaaatat gtctcgatca tctttcccca ttttgctcgc
    48361 tcagttttgg atacttttgc atacccatat cccggaacat cgacaaaatg taatgcgttc
    48421 tcgatcaaat aaaaattcaa tgtctgggtc tttcctggct taccggaagt acgggctaaa
    48481 ttctttcgat caatcaatgt gttgataaaa gaagatttcc ctacatttga tcgtcctgcc
    48541 agagctattt ctggcaattg tgtatctgga tattgttttg gtgccactgc acttatgata
    48601 atttcagctt gatggacttt catggtctct ctccttaaca aggtgatgaa taaagcaagc
    48661 ggctgtcgca aaagccaaaa tgacttttac ggcagcctct tttcatcaac ccgctttttt
    48721 ctctgaatct ttatagatta ctgttggctc accagacaat tcagctgctt cttttgtgat
    48781 aatcactttt tcgatgtttt catttgaagg gatatcaaac atcacatcca tcatgatttc
    48841 ttcaatgatg gaacgaagtc ctcgagcacc ggtattgcgt tcgattgctt ttttcgcaat
    48901 ggctctcaac gcttcaggtt cgaattcaag ttcggtatta tctagagaaa gaagtttttg
    48961 atattgtttg actagcgcat ttttcggctc agtcaagatc cgtaccagat catctgttgt
    49021 caatttctct aaagctgcca taacaggtaa tcgtccgata aactcaggga tcaatccgaa
    49081 ttttagtaaa tcttcaggaa tgatatgctg catgacactt tcgtcttcag aaagtttttg
    49141 gttttgtgta ccaaatccaa tcgtcttttc gcccatacga ttcttcacaa tcgtttcgat
    49201 gccatcaaat gcaccaccta cgatgaacaa tatgttcgtc gtatcaatct gaataaattc
    49261 ttgatgtgga tgtttacgtc cgccctgagg tggcacactt gcaacagttc cttctagaat
    49321 tttcagcaag gcttgttgga caccttcgcc ggaaacgtca cgagtaatag atacattttc
    49381 gcttttacgc gcaattttat cgatctcatc aatatagatg atcccttttt ctgcaagttc
    49441 cacattgtaa tcagcagatt gaagcaattt aagcaaaatg ttttctacat cttcccccac
    49501 ataaccagct tctgtcaaac ttgtcgcatc tgcgattgca aaaggtacat tcaatgtttt
    49561 tgctaatgtt tgtgctaaaa atgttttacc agaccctgta ggtccgatca agcagatatt
    49621 gcttttttgc agttcaacat catctgtgtt ttcttgtgct tgctgattga cacgtttata
    49681 gtgattgtat acggcaacag ctaacgagcg ttttgcgcga tcttgtccaa tcacgtagtt
    49741 attcaatact tcaagaattt ctagtggttt agggacttca gtgaattcgc gtacagcttc
    49801 ttcataaaat tcttcatcaa tgatttcttt acataggtcg atacattcat tacagatgta
    49861 gacccctgga ccagctacga tctttttcac ttcttcttgg gttttcccgc aaaaagaaca
    49921 gcgtacggtc tcattgctac ttggattgtc atacatggtc ttcacccctt aacttgcaaa
    49981 aagtatgcaa gaaactatca aagactttac agtcttttac tatcataaca tagtttagta
    50041 aaaagaaaaa gtgtttaaca aaggatcaac tgacctatac ctttgcattt tttactctta
    50101 acaaaaaata aggaactgtg acaaaatcgt gtcacagtcc cttatttcga ataaacaatt
    50161 ttctagaagt agcttcttca gaaatgattt attacttgat ttctattctt tcgcttctgt
    50221 cgctgtacct gtgatcaatt cgattgcttt tttcattgtc acatcatgtt ccagcatatc
    50281 ttctgtcaac acgcgtttga tttgttcgat tggcatgttg tatgtttctg ataattcttg
    50341 gatttctgca ttgatttctt cttctgttgc ttgaagattt tcagcagctg caattgcttc
    50401 gatcacaaga tttgttcttg tgcgcatttc tgcttcacct tcgaattgtt tatgcaagtc
    50461 ttcttctgta gaaccagtta attgatagta catttcagga gagatacctt gacgttgcat
    50521 gttgttcaag aattcgtcca ttgaacgatg tacttcatca tgaaccatca cgtgtggcaa
    50581 ttcaacgatt tctgcgtttt caacagccat acggatcgct gcttcatctt ttgcatcgtc
    50641 cgctgctttt tcttttgttt ctactaattc tttgcgatat ttttctttca attcgtctaa
    50701 tgttgatact tcgtcatcaa catcttttgc gaattcgtca tctaattcag gcacttcttt
    50761 tgcttttact tcatggattg tcactttgaa gactgcttct tttccagcaa gatcttctgc
    50821 ttgataatct tctgggaaag ttacatttac atctagactt tcacctgatt tatgaccaac
    50881 taattgatct tcaaaacctg gaatgaatga gcctgaacct aattcaagtg agtaattttc
    50941 gccttttccg ccatcaaacg cttcgccatc tacaaagcct tcgaagtcga ttactactgt
    51001 atcgccattt tcagctgcag catcttcttt gataactaat tcagcttgtg cttcttgttc
    51061 acgtttgata cgtgcatcca cgtcagcatc tgttacttca cggtcttgtt tttcaacaac
    51121 tagatcttta tattgtccta attttacttc tggtttcact gttacttcag cagtgattac
    51181 ccagtcttga cctttttcca tgctttcaac atcgattttt ggttgagaaa caggatcgat
    51241 gccagcttct ttgacagcag cttcataagc ttctggtaat acagcattca atgcatcttc
    51301 atataaagct tcttcaccgt acatacggtt gaatacttga cgagaaactt tccctttacg
    51361 gaatccaggt acgttcaagc tttttttcac tttattaaac gcagttgtta atcctttttg
    51421 gatttcgtct tgcgcaatcg taaattttaa aacaccatca ttcgtgcctt ttttttcaaa
    51481 tgttgcagtc atttaattcc ctccgagttt agaaattcat tttatacatc aaaaacgttt
    51541 catgcatacc tttaaatagt acactaaccc tttcaaattg taaacatatt gaatggatag
    51601 aatccttgtt tttcataaca tttttatctt tttcactgat aaaatctaat ggaagaagat
    51661 catttgctgc aaaatttttt ctcttttttt taaaaaatct tgtttttcat cttctgtacc
    51721 ttcatacatc gtttttcctg tacacgcctc tacagtcagt tgaaaccagc gcttcgggtc
    51781 ttcgatgtat gtatcataga caggataaac aattgcagat tgcaacgtga attcttcttt
    51841 taacacggaa ctaagcagcg catcttcatt cccgtaacga tctgaaaata cacataattg
    51901 ctggtaactt gcctgctgct gcggctttgg cagatctttt ggtatgactt tgactaactt
    51961 ttcttcaatc gtcaaataga aaacaggatg gcattcgttc aattgcctaa gtgtctccag
    52021 taattttgcc cttgctaaaa tatggacctc tggcgataca ataagtttac tcgctgtttg
    52081 gataaactca tgataaggaa gctgttcgat ctcatcaata gacgcaagct gacgtgcagg
    52141 ttccaacgaa ggaagttcct ccgatttatt gtggagtgcc ttgatcttct gcctctccat
    52201 ttgtccggat aattcttctg caaattggat tttttcaatg acccgctgct cgaaagcttc
    52261 ataaaaatct gtacttgcta tcaattttct agcatataaa aaatcttgtg tactgattaa
    52321 caagtcaaaa taaaattcag caaactcctc attttgaaga tactgttttt catgcaagag
    52381 tgcttgcttc aatgcttctt ttttctcgtc caactcgtaa agacaaaaaa caagcaggct
    52441 attagcctca aagctttctt tcaactcgta agctcgttga aataattctt ttgcctgctg
    52501 atattgctgg tttgctagtg cttgttgtgc cactcgcatt aaattctcat atttttctgg
    52561 aaaatcaatc ggcttcacgc agtgtcctcc tcttgctcat attcagctca tgttcaatag
    52621 tagcaaaaca aaaaaagcat gacaattaaa aataactgaa gcaccctcta aaagctagat
    52681 tttagatctg acttttagaa ggtgctttca actgttactg ctttttattg ctcatcagct
    52741 gttgacttcc tggttgaacg ctttgatcag attgatcgta acaacacttg tattagtgaa
    52801 aaaatcgccc agatgttgct ttttctgatt aaagactgct ggaagatacc ctaacatcag
    52861 caaaggaaat tttagaatga accggcaagc accttctcta actaaaacgg ttgaccagct
    52921 aagttcttct tcatcaaagc tgatgactcg aataccaaag atcattttcc caatcgtttg
    52981 gccatgattg aatttcgtca ataaaataaa atacgctaga taaataagta aggctgtgaa
    53041 tccgtagaga ctcagataag aatctgaaaa attaagccaa cctagatttt tggcaatacc
    53101 aagtgttaaa cgcgtaatag ctccgataca caaaagatcg accaagaagg caaacattcg
    53161 gataaaaaaa cctgcataga aatacttagg aaaatcattt gcttttggcg gttcatttct
    53221 tgtgtccgta tactttttcc atttacgttg tttctttttg atttcttcgg gcgtcaaagg
    53281 ctctctttca aaagagctca gtaccttttg ggaaaagttg gagtcaggtc ctacagcagg
    53341 ctgctgttgc ttatcttttt cttgttcctt attttcattt gaaagctctg acatgcttac
    53401 tcacctccgt aataatacat tgcttttggt gattccgctg tccctagatt ctcaagaacg
    53461 gataagatct gactagtctc agaaggcttc aatccctgga attctgctag tttacttcct
    53521 aaccatgtac tagcaaaccc agatggcgtg gaagaatatt ctactagttc cgcatcttca
    53581 agctgttgtt cctttcgtat agcttttaaa gcatcttcag gaaatcccaa ttcatcgact
    53641 aaacctactt cttttgcttg gacaccatca taaatccttc catcagcaat ttttttgact
    53701 tcttcttcag atttattccg tccctcgctg acgattgcta caaaacgact atatgcgctg
    53761 tcgatatatg cttgaagcac cgcttcttct tcttttgtct ctggtcgcgt tcctgaaccc
    53821 atatctttca acgctccgct tttaactgtt gtatcttcca cacccagttt ttctagaagt
    53881 cctgaataat tcaatcctga catgatcaca ccaattgagc cggtcactgt ttcttctgtt
    53941 gcaaagattt tatctgcttg agcagaaata tagtagccac cgctagctgc catgtttttc
    54001 atgctgacat acattgggat atcatgttct ttacgaatcg tatccaattt cttagcgatt
    54061 tccgcacttt cgtagacacc gccaccagga gaatttactt ctaaaaagat acctttgact
    54121 gttggatctt cttcaatcgc cttcagttgt tccataaaat ttttatgatt gtaaccttca
    54181 gaagcaaata aacctgaaga ccctcccgca gcaatcgttc catctactga taattttacg
    54241 attttttgcg tactgtctcc ctcttccaac acatttggag ctagttcttc atccccatat
    54301 aaccaactgt tcaatccctc aatttgatcg ttttcctgag gcttagtcaa actagctgaa
    54361 actaacgaaa ccacaaataa tcctgcagca atcagaactg ctgcccaacg tcttttattc
    54421 attctttctc ctttctaata caagtttttt atgacgatca cagtttctga ctgctcagaa
    54481 gtgtcgaacc gctctgcttt ttcttcccgc gcatacccgg aaaacgactc ttttgttaat
    54541 tcatcttcta ccgtaaactc acgagcttga gcaacttcca aggcatcagg tgcgatttct
    54601 tggatgctat cccagccagt atctaaaaat attttcgtat catctgatac accagctgat
    54661 gcttcgaatt tggacaattg tttttttaac attcccagtg tcatgatctc aatttttgaa
    54721 tccattttta ctcctcctct atccgattac tttctattgt accgaactcc tgaaaaagat
    54781 gatagataaa aacccattat tttttgacat aaaaaggaca tttgacaaag aatttgatat
    54841 ataccaattt attttttatt ctttttttgt tgacaagaac attcgcaaaa ggttatgatt
    54901 ttaaatgttt ccagataaaa aacaaaaagg aggatagtta taccttttag gatagcgcca
    54961 ggtctgtgta aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag
    55021 ggactgcact ctacagaaaa tccacaaaaa atgtctgcaa agataaaaca aaaggatttt
    55081 cctgcagctg gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg
    55141 gaattgttgg aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa
    55201 aattagaata ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt
    55261 atctggtcaa agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta
    55321 caggaaatat aggtattggt catacacgat gggcaactca cgggcaacct tctgaagaaa
    55381 acgcccatcc acatacttcc caaagtggac gcttcgtgct cgttcacaac ggcgtaatcg
    55441 aaaactttga agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg
    55501 atactgagat tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg
    55561 cgtttttaaa agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga
    55621 cagcacctga tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg
    55681 atggattcaa tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg
    55741 ttgagattga agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt
    55801 ttgcaggtga catcgtagaa cgttcttcat tcgaagcaca agtagatgct tcagatatcg
    55861 agaaaggtac ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc
    55921 gtcgtatcgc tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg
    55981 tcgatacatt gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg
    56041 cggggttagc aggtaaacag actttggaaa aattgacaca gattcctgtt gaggttcatt
    56101 tagccagtga atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct
    56161 tgagtcaaag tggcgaaaca gcagacagcc gccaagtgct ggtaaaaatc aaccgtctcg
    56221 gctacccttc acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct
    56281 ttacactgct attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg
    56341 cacaaatagc tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa
    56401 cttctcttgt attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg
    56461 tcatcgccca aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa
    56521 atgcctttta cattggacgt ggtgctgact acaacgtttc tcttgaagct gctttgaaat
    56581 tgaaagaaat cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa
    56641 cgattgcttt gatcgaagaa ggaacaccag tgatcggaat catcagtgaa gaagtgactg
    56701 gtgcgcatac tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta
    56761 ttgtctcaga gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt
    56821 atctaactac tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat
    56881 tacggggatt cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat
    56941 aaaagaacaa ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg
    57001 aaaatatctc ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat
    57061 agtaattaac tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac
    57121 cggaaggacg aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca
    57181 cttttttgat tgccggaaca tccatcgcac cgtttttatc acttacgcgg atattcacta
    57241 atttttgcgg atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt
    57301 tcatgatatt cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta
    57361 agaaaatcat gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt
    57421 ctacaacgta acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg
    57481 ctttgtggaa tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat
    57541 ttttttctgc caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc
    57601 caagttcatc caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg
    57661 ctcctttttc aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccgtcat
    57721 tgatatttaa cccgtctgga tttgtgccca ttgtataaaa atctgtttca agatcggcaa
    57781 acaaacgatt aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac
    57841 cggaaaggtc accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg
    57901 gaaattcttc tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag
    57961 catctaataa tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac
    58021 cgaaaaattt gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg
    58081 cgcttgcttt ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct
    58141 ggaacacttc gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac
    58201 ctgagattct tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct
    58261 ggcttaggac ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct
    58321 tgttggcttc accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac
    58381 tcctttaact taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc
    58441 tgatgtttct tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat
    58501 ggttgttgtc gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt
    58561 attttcttgt gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg
    58621 tgtaatctcc acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc
    58681 aattttacga gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc
    58741 accgatcgat gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact
    58801 gaaatcatag ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac
    58861 cgacttgctt ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat
    58921 acttaatact tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc
    58981 atctgtgacc atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt
    59041 gtcacctgta gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc
    59101 agatggtgtg aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt
    59161 ctcaaccgtt actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt
    59221 ttgaattttt agcggaactt catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac
    59281 gcggaacatc cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga
    59341 aagtttgaca gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga
    59401 aatcttgatc ggcacccccg taactgtttg attatacgct tcatttccag aaagcgtatt
    59461 tggaacggac tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa
    59521 actgtaaaga atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc
    59581 ataccgtcta ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatt
    59641 agttctctac gcaagattgc caaatattct tgctgggata agccagccat cagttcatta
    59701 tctaacgtga tgctgacgtc cccggtttct tcagagacaa cgatggtaat cgcgtcactg
    59761 acttcgctta taccgacagc tgcccggtgt cgagtcccga attctttagg gatcaacata
    59821 ctttctgata gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact
    59881 gcaccgtcat gcagcggtgt attaggaata aagatattga tcagcagctc cccagtgata
    59941 tctgcatcta aagcaatccc tgtctcaata tactcatcta atccagtatg acgttcgata
    60001 gtgatcaacg caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag
    60061 atcatcttct catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca
    60121 agatgttcca gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg
    60181 tacgtaatga cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg
    60241 attcggataa caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc
    60301 agcagttgga tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc
    60361 aaaaaattca gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa
    60421 agttccccga tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag
    60481 tatatcatat gttttaattt tagaggctga tatgctcgta tttttcttga gaaaaacgca
    60541 taattttcaa gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa
    60601 cttcagagaa ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt
    60661 gttccatttt tttacgtcgt tctgctctgg cagctcttct agcagctctt ctttcttctg
    60721 cttcaaggtc cgtcgttttt tcttttctag tcttaacggg tacatcgata gattcctctg
    60781 gttcaagtcg tttcttgatt ttttctaatt ctcccgtcag tgcagcatag ttgtaaaaac
    60841 gtgttttagc gtcgtggaca gtcttttcaa ataaagcttt tgcaagattt ggatttgcgt
    60901 tatctagcga ggaaaagcga acttgtttcc tcatgaaatc aggcatagca gagaaatcag
    60961 gttttttgta gtccaaagtc attgggttct tgtttttttc gaccattgta gggttatatc
    61021 gatataatga ccaataacca gaagaaacag cttcttttgc ttctttaagc gattctttca
    61081 ttccgccaag caagccatgt gtgatacaag gcgtataggc aataatcaga gaaggaccag
    61141 gatacttttc tgcttcttca aatgccttga tcgtttgcat ttgattggca cctgaagcaa
    61201 tttgcgccac ataaacattt ccatatgtca tcgccatcat tcctagatct ttctttgaag
    61261 catactttcc actagccgaa aatttagcga ttgccgaagc tggtgttgct tttgaggttt
    61321 gaccgccagt attggaatag acttcgttat ccaaaacaag gatattcacg tctgctccgc
    61381 tggcaagtac atgatcgatc ccgccaaaac caatgtcgta agcccatccg tctccaccaa
    61441 tcatccattg gctgtttttt acgaatagat cctttctctt gtatatatcc tccagttcag
    61501 ggaaaattga tcgttcgctt tcgatcgcag cttgcagttt tgctgctctt tgctgcgttc
    61561 cttcactctc aaacatgtgt actaaccagt cttccatcaa ttctcgtagt tcttctgata
    61621 cttttggcaa tacttctttg attgaacttg ccaaagcctc gcgacgagtc tgtgccgcta
    61681 gaagcatacc ataaccaaat tcagcattat cttccaataa agaatttgac catgcaggcc
    61741 cttgaccaca ttcattggtc gtataaggag aagcaggaga agcaccgccc caaatagaag
    61801 aacagcctgt cgcattcgcg atcatcattc gatcaccgaa catttgtgtc aataatttta
    61861 cataaggtgt ttcgccacag cctgagcaag cgcccgagaa ttcaagaagc ggttgattga
    61921 attgtgtaga caagacagta ttctttcctt tgactggatt tgctttttgt cttaatgtca
    61981 ttgcaaaagc ccaattcaca gcttgttctt tctgttcttc ataaggcttc atcactaaag
    62041 ctttttcttt tgcgggacaa gcctctacac acagaccaca acctgtacag tcttccactg
    62101 aaacttggat acggtatttt acgccgtctg cgcctcgcat ttctctcacg ataaatcctt
    62161 ctggcgcttc ttccatttcc tcttcatctg ctaaaaatgg acggatggca gcatgaggac
    62221 aaacaaaggc acattcatta cacatcgtac agcgatcact aatccactca ggtacttcta
    62281 aagcgacgcc ccgcttttcc atagaagccg ttcctaaagg catttcgcca gttgtcattc
    62341 catttgctac aagtgtacca acagagagtt gatttccttc ctgtgcattc actggttcaa
    62401 gtatttcttg tatataacca gtgttccttt tattgatttt ttcaggcatc tccaacgttc
    62461 tccaatggtc tgggatcgcg acttgatgaa gcagttcggt cgtccgatcg attgcttgta
    62521 tgtttttttc tacgatagcc attgatttat gtccatagct tttcagggct tcttctttta
    62581 gcagcggaag cacctcatca aaaggaatga tgtcagctaa tttaaaaaaa gccgtttcca
    62641 ttgccgtatt gatccggcgt cccaaaccga cttcttgggc caatctcatg gcattgatcg
    62701 tatagaatct aatgttattt tcagccaagt aacgttttaa ttttaagggc agatgcgttt
    62761 ctaattgttc gtcgctccaa agagtattca ataaaaaaat gccacctggc ttcaatcctt
    62821 tgaccaagtc atagctatgc aggtaagctg gtgtgtgaca ggcaacaagg tccgcatgct
    62881 cgacaagata cgctgaacgt atcggcgtat ctccaaaacg aagatgagag acagtcagac
    62941 cgccagattt tttcgaatca taataaaaat agccttgcgc atatttatcg gtgtgatctc
    63001 caataatctt gatagctgat ttatttgctc caactgttcc gtcagatcca aatccccaaa
    63061 acttggcctg gaatgtttgc ggttctgtca aatccagact ttcctttggt tccaaagatt
    63121 gataagtcac atcatccacg atccctatgg taaaccgttt tttgcgtatg cttgggtctt
    63181 ttttcaattc atcaaaaact gctgagattt ggtcgggagt cacatcttta gaccccaatc
    63241 cgtagcgacc accaataaca gccgggcgaa gttcagaatc atataacgca ctttgaacgt
    63301 ctaataagag aggttctcca cctgcccctg gttctttact tcgatcaaga acagcaattg
    63361 tttttactgt atgaggcaac ttttgcacga atgtttccac tggaaaagga cgataaagat
    63421 ggatattcaa aaaacctgtt ttccgtccgt ttgcattcaa gtaatcaatc gtttgttcaa
    63481 tcgtctgtgc aactgatccc atagaaacaa tgacttcttc cgcatcgtct gctccgtaat
    63541 aagtcaccaa gtcataagaa gttcctcgta atcggttgat ctctttcata tatttttgaa
    63601 cgatttcagg taatttatca taataggggt tgatcgtttc ccgttgttga aaatggatgt
    63661 ctggattctg gttcgtacca ctaacagtcg gatgattggg attcatccct cgtttacgaa
    63721 atgaagctaa tttctcctga ttgatcagag gagctaattc ttcatattcc aaaacttcga
    63781 ttttttgaat ctcgtgactc gtacggaatc catcaaagaa attcaaaaaa gggacttctc
    63841 cttcaataga agcaagatgg gcaacaggtg ctaaatccat cacttcttgt acactgcttt
    63901 cagctaacat agcaaatcct gtttgtcttg cagccatcac gtctccgtga tctccgaaaa
    63961 tattcaacgc atttgtcgtc actgcccgac tagcaacgtg gaaaacactt ggcagtagtt
    64021 ccccagcaat cttgtacata ttcggtatca tcaaaagcag cccttgtgaa gcggtatatg
    64081 tagttgtcag tgcaccagtt ttcaatgatc catggaccac accagctgct cctgcttcgg
    64141 attgcatttc tactactttt actggttgac cgaatacgtt ttcttttcct gctgctgacc
    64201 attgatctac taattcagcc atggtcgaac tgggtgttat tggatatatt gcagcaatct
    64261 cggtaaatgc ataagaaata tatgcggctg ccgtattgcc atccattgtt ttcatttttc
    64321 gcatgattca tcatccttgt tcatattctc tcttattatc tgttccatta taacgtaaaa
    64381 catgccattt ttttctttta tttataaaaa tattttacat gtatctattt gaattggtca
    64441 tctaattttt agacaaacag tctaaatcgt tgcctttttt tgtcagacat gtataaacta
    64501 taagcgaaag aggtgtttta acatggatat atcagtgatt gatgcaacga aaacaaatac
    64561 acaaaaagga atcctttatg gttcatcgaa tgctcctaaa aaaatggtcg aattcatcaa
    64621 cttagcttgt ccgtattgcc gacaatggtt tgaagaatct tatgagctat tagaagaagc
    64681 agtccaaagc gggcaattgc agcgagtgat caaattgttc gataaagaaa aagaaagctt
    64741 acagcgaggg aacgtgatgc accggtatct cacaatcagc gatggccaaa aagcgatcaa
    64801 agagatcaaa caaatattcg atactcaaga cgagtggaaa catctttctc tccaagaagt
    64861 agcggatttt gcagtagata aactaaagct gacagaacaa aaagacgaac agctgagcca
    64921 agctgtcatc aacgaagctg agcaagcaca tattcgattt gttccaactg tcatcttggg
    64981 taaagaaatc tttgatgaat ctatttcaat agaggaatta aaagaattga tccaaacaaa
    65041 ataaaaaaat aaggagcgtg ggacaaaagt aaagaacact tttgtctcac gctctaaaca
    65101 cgtataaacg gcggaagcag aagcaactcc ttcttatttc ttggagttaa acgcttctgt
    65161 cccagcctcc ttattccgaa taaatggtgt ccaaaagctt gcatctgcca gattatctca
    65221 tttcttatga caagctaagc aaattatctc caccaaataa tttattcata tttttgactt
    65281 gcgcatacta actaattctt aaattttcat acaaaatttc tcaatttccc ttaacgagta
    65341 atatttatgt acggtgattc tcactagtat cccaatcact ttttaagtta tcccgatttc
    65401 aattctactt caaaaatagt tgcttttatg tatgctgtta gttgattaga tggtcatttg
    65461 ttgagctagg tcgtttattt taaacaagtt gtttctttag cttataccta tctcgtctac
    65521 caaacgcaag atggcaaaca caaatgcata cgcatctgta tttgccactt tgattcgtat
    65581 aaagctaaca actattaact cctctcagct aatagttgct ctctttttta ttcagattca
    65641 tttttgctga tcacagccta gtatttcaat ggttttgaac actaaaccaa attgttccat
    65701 tacaacattc actggctgat gaaatggatt agtagatttc gattattcaa agcgattttc
    65761 tattggtgga tcgtgttccc aactaataag acggattcca aacctatcgt acagatcttc
    65821 taaaccactt ataaattttg cacctatttc aggtgtttta ttgcgtggat attctattgt
    65881 tacgccatta aatggatacc aattaggatt aggctctctt tttttctgta catctcccat
    65941 agaatagtta gcactttctg ggacataata tattcttcga ccatcctcta attcatctaa
    66001 taagatattt cgtgatcgtc tatcacttgc taaatgtaga cgccacgtgc gataccatgc
    66061 catgctacct gcatctgcag aaaatccatc aaataatgca acaattgtat cttctatcac
    66121 aatcctttcc ccatctactt catattctaa tctaaaatca aactcccctc gggtaatttc
    66181 tggtcttggt ggcttaggac ccaatattat tctacttaaa accgcattcg ttcccagatg
    66241 aaacacagct ataacaacaa taatgattaa tattttgttt ctatttgata aatttctcat
    66301 tattcgcaca tcacctctac attctcacat attagttcgt aatactcctt taatatcaaa
    66361 atatctactg gtcgtaataa tattcgctat gaattcctac tactcgtata agaaaggcca
    66421 aatcatcagc ttttacttgc tgatgatttg gcttgtttct atttatcgta attgttttct
    66481 aatcaccaaa attgttaaca atcggttcag atatttccca gttgattaag gtaattccgt
    66541 attgtgtcaa aacttcttgc gcttctccga aattaagtac agttcttatg tatccacttt
    66601 ctcctaatat aaagtctacc tctcttttaa aaccttcctc gagatttcta agggctatat
    66661 gtggttttaa tgacattgat tgtacatttt cccccatata atatcgcgca cttcctcgac
    66721 taaaatagat tcctagatcg tccccaaaag gtagatcttc tctaccacta gctaatctac
    66781 ttctccatct tcgttctctt ttcatagaac ctgcgctgaa ctcacacccg ttaaactcag
    66841 ctatgacagt atcttcaatt atgttaatct gtccatctag ttcgtattca atcctaaatg
    66901 gaaattctcc ataggtgatt tccggttcgg gtattttagg tgagattaat gcaaagaaag
    66961 gaaatattaa gcttggcaac atcaaaaaaa ctcctcctat gatcacaatt cccgatgtaa
    67021 tccaaaatat aatttgtaca attctcattg atccattgta ttccatttta ttccccctat
    67081 tactattcat atccgcctat ctatatcgat cttccaatgc agagataatt gcttccatac
    67141 cttgattttt tactgagtta cctatgcgag atatcattct ccactaaggt gcatcatatt
    67201 gtctatctaa catgattaat tctccaatag gtgtatactc ctccaaaaac aacatttaat
    67261 gcatctccct cgacaacata agctaccatg tttgctgtat atgtgtttga gtctaattca
    67321 taagcagata aatttactgt cgctggatta aatataatcg cattcgtatt tatagctact
    67381 gaatttgctg cttcagcacc accttttgaa tgtccgatca ttgtgatttc aatagtagga
    67441 tttacgtgga cagccctcac cgtttaccct gaccattata gaaatcgctt acttttttga
    67501 actacgcaac aaaggataca atgctcctaa cttcactgtc tccatttttg tccactaagg
    67561 aatataaaaa ataggcatta attcatttaa ttcggtcaca acacgttacc ttttaaatca
    67621 ttatactgta tctcatacat tattatcaat aaactattat aaaaatgcaa aaaatgcttt
    67681 atcaatctat tttgtaattg gtcataatat cattgaaatc ataccctgta tcgatttttc
    67741 ctatgaatct cgtctatttg tgattgacga aaaagaggca agacagacac tggaatggta
    67801 attttaccca ctattttgct ccaactattt gtaatcgtac ccacttttga aataccgaga
    67861 tgatcatttt aattgatatg ctgattccca agcaaaaccc caagaaatta aatgctctat
    67921 cgcatctagc ttcttgggtt ttgcttatat aaattccaac atttaaattt tttatgctgt
    67981 tcggtctcag aaatgccgtt tttgcttata tcacaatatc aagatgtcaa attattcgtg
    68041 ttgccgatga ctttgattaa tttttttcaa attgtttatt aagactaatg ctgtcttttt
    68101 gcagatacca atgttcgaac tttttaacat tatcatatga tcctgcaagt tttaacttct
    68161 taccattaga tgttatcaaa gttataatta accttgcctt tttcccatta ggatctttta
    68221 ttttatgaat tttctgcagg taatctctcc taatggcagc tatttttacc tcatcagtgc
    68281 tgataaacca ttgatcatcc acatacatac tgcctgttat gttgtgtttt tccatttctt
    68341 ccgagaacga aaagtttaag gctcgttctt acttccaaag ttgaatgagt ccatggattg
    68401 gacttagtgt gagaattgag aacaacaata agaatccata tcctcccgca aacatcccta
    68461 aggctatact gtctctccat ccataagtag gattagaaga gaaaagagtc accgtttgta
    68521 ataatatgaa aaggaataat ccagcacaaa caccaaagat aacaactcca aacattgaat
    68581 ttttatacaa tgaccattta tttataggct tttctttcat tttacttccc cctactgttc
    68641 tgttcacacg gaatgaattc aaagttcata agccctcctc tttgaacata tgaatacgac
    68701 ttgctaacta tactttaaaa aagcttgttt taagcggtta taggcgagtt gtaatctcta
    68761 ttcatctcat tagcaaataa cttgccgaaa agtctactga aattaaagca gatagtggaa
    68821 gaattattta gccaggatag acactatttg tgaaacacat gtctttactt ttgaaattct
    68881 atgatgaaaa gccttggaat acagtagctc ttaattggta atactttttc cattataaat
    68941 aacctctttt cattttatat ttatcccctc taaaaataat atctaatcta atattttaaa
    69001 cttatatttc cctcgctgtg ctaatagagc attactaaat aaatagaaac tagaaaaaag
    69061 cattacgcct gccagaataa accaattatt tgt
//
LOCUS       DACBZK010000006        59637 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.006, whole genome shotgun sequence.
ACCESSION   DACBZK010000006 DACBZK010000000
VERSION     DACBZK010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.006"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(451..1761)
                     /locus_tag="IVD66_000459"
     CDS             complement(451..1761)
                     /locus_tag="IVD66_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAP6144707.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="IVD66_000460"
     CDS             complement(1773..3191)
                     /locus_tag="IVD66_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6144708.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="IVD66_000461"
     CDS             complement(3431..4999)
                     /locus_tag="IVD66_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HAP6144709.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="IVD66_000462"
     CDS             complement(5003..5413)
                     /locus_tag="IVD66_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAP6144710.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="IVD66_000463"
     CDS             complement(5410..6333)
                     /locus_tag="IVD66_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HAP6144711.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="IVD66_000464"
     CDS             complement(6330..7208)
                     /locus_tag="IVD66_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAP6144712.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="IVD66_000465"
     CDS             complement(7195..8532)
                     /locus_tag="IVD66_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAP6144713.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="IVD66_000466"
     CDS             complement(8535..9638)
                     /locus_tag="IVD66_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAP6144714.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="IVD66_000467"
     CDS             complement(9712..11220)
                     /locus_tag="IVD66_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP6144715.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="IVD66_000468"
     CDS             complement(11186..11878)
                     /locus_tag="IVD66_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP6144716.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="IVD66_000469"
     CDS             complement(11900..12874)
                     /locus_tag="IVD66_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6144717.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSSNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="IVD66_000470"
     CDS             13174..14046
                     /locus_tag="IVD66_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6144718.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14504..16702)
                     /locus_tag="IVD66_000471"
     CDS             complement(14504..16702)
                     /locus_tag="IVD66_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6144719.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYMNNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16934..17926
                     /locus_tag="IVD66_000472"
     CDS             16934..17926
                     /locus_tag="IVD66_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6144720.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17986..19407
                     /locus_tag="IVD66_000473"
     CDS             17986..19407
                     /locus_tag="IVD66_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HAP6144721.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19400..20899
                     /locus_tag="IVD66_000474"
     CDS             19400..20899
                     /locus_tag="IVD66_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009224330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HAP6144722.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20938..22332
                     /gene="uxaC"
                     /locus_tag="IVD66_000475"
     CDS             20938..22332
                     /gene="uxaC"
                     /locus_tag="IVD66_000475"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAP6144723.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22491..23174
                     /locus_tag="IVD66_000476"
     CDS             22491..23174
                     /locus_tag="IVD66_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HAP6144724.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23176..24012
                     /locus_tag="IVD66_000477"
     CDS             23176..24012
                     /locus_tag="IVD66_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP6144725.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24023..25777
                     /locus_tag="IVD66_000478"
     CDS             24023..25777
                     /locus_tag="IVD66_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6144726.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(26053..26394)
                     /locus_tag="IVD66_000479"
     CDS             complement(26053..26394)
                     /locus_tag="IVD66_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAP6144727.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26462..28633)
                     /locus_tag="IVD66_000480"
     CDS             complement(26462..28633)
                     /locus_tag="IVD66_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAP6144728.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGATETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28844..29701
                     /locus_tag="IVD66_000481"
     CDS             28844..29701
                     /locus_tag="IVD66_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAP6144729.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(29772..30629)
                     /locus_tag="IVD66_000482"
     CDS             complement(29772..30629)
                     /locus_tag="IVD66_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP6144730.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30614..33316)
                     /locus_tag="IVD66_000483"
     CDS             complement(30614..33316)
                     /locus_tag="IVD66_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAP6144731.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33329..34618)
                     /locus_tag="IVD66_000484"
     CDS             complement(33329..34618)
                     /locus_tag="IVD66_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HAP6144732.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34768..35814
                     /locus_tag="IVD66_000485"
     CDS             34768..35814
                     /locus_tag="IVD66_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6144733.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35816..37969
                     /locus_tag="IVD66_000486"
     CDS             35816..37969
                     /locus_tag="IVD66_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAP6144734.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38442..39893)
                     /locus_tag="IVD66_000487"
     CDS             complement(38442..39893)
                     /locus_tag="IVD66_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6144735.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39890..41614)
                     /locus_tag="IVD66_000488"
     CDS             complement(39890..41614)
                     /locus_tag="IVD66_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP6144736.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41607..42221)
                     /locus_tag="IVD66_000489"
     CDS             complement(41607..42221)
                     /locus_tag="IVD66_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP6144737.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42566..44023)
                     /locus_tag="IVD66_000490"
     CDS             complement(42566..44023)
                     /locus_tag="IVD66_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6144738.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(44064..44984)
                     /locus_tag="IVD66_000491"
     CDS             complement(44064..44984)
                     /locus_tag="IVD66_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6144739.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44996..45943)
                     /locus_tag="IVD66_000492"
     CDS             complement(44996..45943)
                     /locus_tag="IVD66_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6144740.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46422..47141)
                     /locus_tag="IVD66_000493"
     CDS             complement(46422..47141)
                     /locus_tag="IVD66_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAP6144741.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47190..48836)
                     /locus_tag="IVD66_000494"
     CDS             complement(47190..48836)
                     /locus_tag="IVD66_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP6144742.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            49015..49605
                     /locus_tag="IVD66_000495"
     CDS             49015..49605
                     /locus_tag="IVD66_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP6144743.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49697..51202
                     /locus_tag="IVD66_000496"
     CDS             49697..51202
                     /locus_tag="IVD66_000496"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HAP6144744.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51286..52638)
                     /gene="celB"
                     /locus_tag="IVD66_000497"
     CDS             complement(51286..52638)
                     /gene="celB"
                     /locus_tag="IVD66_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAP6144745.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52638..53156)
                     /locus_tag="IVD66_000498"
     CDS             complement(52638..53156)
                     /locus_tag="IVD66_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144746.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53172..53498)
                     /locus_tag="IVD66_000499"
     CDS             complement(53172..53498)
                     /locus_tag="IVD66_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HAP6144747.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53511..55490)
                     /locus_tag="IVD66_000500"
     CDS             complement(53511..55490)
                     /locus_tag="IVD66_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP6144748.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55511..55825)
                     /locus_tag="IVD66_000501"
     CDS             complement(55511..55825)
                     /locus_tag="IVD66_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HAP6144749.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55993..56286
                     /locus_tag="IVD66_000502"
     CDS             55993..56286
                     /locus_tag="IVD66_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HAP6144750.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56364..57476)
                     /locus_tag="IVD66_000503"
     CDS             complement(56364..57476)
                     /locus_tag="IVD66_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP6144751.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57629..57853
                     /locus_tag="IVD66_000504"
     CDS             57629..57853
                     /locus_tag="IVD66_000504"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144752.1"
                     /translation="MNGSIKKILRSIDKNLMITEVSYETLQKKKTLIVAAVLFPAPCV
                     CRNCGSAVVDGNRKLMVVKNKKKETIVHFE"
     gene            57863..58042
                     /locus_tag="IVD66_000505"
     CDS             57863..58042
                     /locus_tag="IVD66_000505"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144753.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58236..58406
                     /locus_tag="IVD66_000506"
     CDS             58236..58406
                     /locus_tag="IVD66_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP6144754.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(58830..59570)
                     /locus_tag="IVD66_000507"
     CDS             complement(58830..59570)
                     /locus_tag="IVD66_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP6144755.1"
                     /translation="MTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGL
                     TTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTP
                     GGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVET
                     QAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGE
                     TIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT        17824 a        12191 c        10427 g        19195 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgatct gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt cgatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttacc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagcgt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc
    14461 ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattcacaaa tatttttttc
    14521 gatattctcc cggcgtaatc gattccttct ttttaaagaa acgaataaaa ttttgcggat
    14581 ttcgatattg caatctttct gcaatctctt ttacggagag gttagtctct ttcaaccatt
    14641 tttttgctac ctctaaacga tgattttgaa caaaatcacc aaatttttct cctgtttcct
    14701 ttttaaatac attacttaaa tagttagggt tataatgcaa cctatcagcg atcacatcta
    14761 aagacagatc acgatcatat tctgtgtaga cgatatgcat aatattctcc gacaaatttt
    14821 taaattcatg atcagtgatt gcttgagagc attctgtgat tggcagaact aattgttcta
    14881 aaacaagttt ttctagttct ttgggatgat aattgttcag tgcttttaca taaatttgtt
    14941 tcatgttatc aaagtttttt gaatctactc ccaataactg tcctaattga acgagttcat
    15001 tgatcaagcg gaccgaaact acttcccgac tcaaaggatt tttattttgt gcaaacaatg
    15061 catcaatcaa ttcatgtact aaattcttca cttcctgatt tccagaacga atggcttcaa
    15121 acaatcgatt ttgttcttct atcggatatc taataagtgt tttttcatga gcagcaggaa
    15181 cgatttcctg ataaaaaata attgaacttg gaccagtatt tacacgataa tacagggctt
    15241 cttttgcccg atcaaccgat tgcttgcttt cattcagcgt ttcgaaccgg ttactgatgc
    15301 ctatactgat agttaaattc aagtattctt ttacacgttt ttgaatgagt cggcaatact
    15361 ccatgacttt tttgcttgct tctgcatcat ctttatccat tcgataaata gtggcttgca
    15421 tttcttcatt caaaacgatc ggcagcattc gattttcctt tggcacaatt tccgtgatca
    15481 tgttgttgat cgctaaaagt agcaaatcac gctccccacc gtgactatct tctaacagat
    15541 cgatttgaac caaagctgta taatagcagt cattttgaga actataacca aattgctgca
    15601 accgctgatc tagttctcgc ctttctactc gatttctaaa taaactaagt acaaatagcg
    15661 tttccagctg tggcttttgg gtaactaagt gtgcacttaa cgcttctttt tctcctatga
    15721 tccgactgac tgattgagcg accaaatcta gttctttccc actgaatcct tttgatttaa
    15781 gattcagacg ttcctgtatt tgagaaatcg gacgggcaaa tctgtccgaa aataagtagg
    15841 aaagaagacc aatgagtcct accagtgtta aagacactgc aactagcccg attctcagat
    15901 tgcggatcat tgcgccaatt gcactagagt caacttctaa tctgtaaatc caattattat
    15961 aatctgattt cagtactata tacgttttat ctttttctct tatcactttc agctgattgt
    16021 aatctagatc cacgtccgtt aatacagttg gttgctcttt attttttact gtctgagtag
    16081 taaaaaggtt gccaacttcg ttttcaatag aaagtatgtc ttctccactt tcaccaacaa
    16141 cttgttctat tgtatgtttc tctatcgtag caattcccaa tgcatatttt tctttttcaa
    16201 acattggcaa agaaatcacc atttcgattc ctttgttttt cttttgccaa aataaattat
    16261 ttttgttatt catgtacttc tgttgatact tttcaatttc ctcttcggtc agttgactca
    16321 acgatccatt gattactccc catttaccag ctaaactgac taaatcataa ttattatcat
    16381 ccataacaat cgtttctata aaatttagtt ctttcctgat ttcagaataa gtggagtaat
    16441 ctgtatatgt cagcggatgc ttgaatatgt ccgagaaatt tttggtcgaa ccatacgtag
    16501 aaaacgaata ttcaatcgtt ctaattttcc attcaacgtt agttttaact tgcctgagca
    16561 aattcttttt gtctgttaaa taactcgatt cgatcgattc ataggtattc tggtaaatga
    16621 ataaactaaa tcctatgaca agtacggctc ctaataaaaa catcggtaaa aatattttat
    16681 aaaatactgt acttttcttc attttcttcc tctcctcctt ttaaaataaa aggctttcat
    16741 ttttctgtaa aattgatact catctaatta aatgagcatt ccccgctttc aagaatagca
    16801 taattaaaaa taaaaatcca agtaattttt aacgtgtgca atcttttcat atcaaagatc
    16861 tattgactta tcgtagttat cgtaatatga tgaatgcgtt aacaaaaagt gaaaaagtaa
    16921 ggaaaatgat ggaatggtaa cgatcaaaga tgtcgctaaa gcagctggcg tttctcatac
    16981 gacagtttct cgtgctttga ataacagcag tttaataaaa aatgaaacaa aacaaaaaat
    17041 acgacaacta gctaaggaaa tgaattattc gccaaactat agtgcaaaag gtttagtgaa
    17101 tcaaaaaaaa tatctaatcg gactattttt ctcaagtttg cataaaggaa cttcatcaaa
    17161 tttcctagca gattccattg caggcatcca ttcagtatta gacacaaatt acagtttatc
    17221 tgttgaaagt atcgatgttg ttgatttaac agaaatcaac ctgcaacgct acgatggact
    17281 gatcgttatg agtcaaagtg atgatgatca gcctttcatc gactatctca aagaaaaaga
    17341 atttcctttc gttgttgtca atcgtcacat caatgatcca gcggttatca acgtcactgc
    17401 cgatgatgcg gccggtgtta tgcaggcagt agattacggt attggatgcg gacatacgaa
    17461 gatcgcttat attggcggaa agaaaaattt tcgttcgaca aaagaacggg aaaaaggggt
    17521 attgaaaagt ctaaaaaaag cgagcatccc tgtcaatcca gcctattttt taacaggaga
    17581 ttacagctta gaaagcggcc tccaaaacat ggaataccta ttatcacttt ctgacctgcc
    17641 tactctggtt ttttgcggca acgacgacat agcgattggt gcattgagag ctgtacattt
    17701 agctggcctc cgtgttcccc agaacatttc tctgatcggg ttcgatgatt ctccagtcgt
    17761 ctcctatctc aatccgccgc ttaccaccgt acgtaagcct ttgaaagaaa tgtgtcaaga
    17821 aggaacaaag cttttactag atttgatcga aggcaggacg atcgaacaat ctaaaattga
    17881 gctctccacc ttgttgatcc ttcgtgagtc gatcaattac ttgtaaacta caagtaattt
    17941 tatataaaaa tgttaacgtg tgcataacac agaaaggaag tttatatgaa aaaactgaca
    18001 aaagaattag tgaaaaaaaa cgaagcacct gtaaaagttc ttcagtttgg tgaaggcaat
    18061 tttatgcgtg gatttattga ttggcagatt cagcagctga ataaccaaca attgtttaaa
    18121 ggtaatgttg caatcattca acctttagaa caaggtcttg gaaatatgat gaaccagcaa
    18181 gataatttat atacggtcat tttacaagga ctcagcaatg gcgaaatcgt tgatacttcc
    18241 gagattatca ccgtagtaga acaaatgatc aatccttatg atgaatggga tgcttatcta
    18301 tctctagcag aaaatgacga cttggcctat atcgtctcca atacaacaga ggcaggaatc
    18361 caattcgtgg agactgataa tttaacagat actcccccac agagcctccc gggcaaactg
    18421 acagcctttt tataccgacg tttcaaatta aacaaagctg gctttaccat cattccttgc
    18481 gaactgattg acagaaacgg cgaacgtcta aaagaaatca ttttacgcta cgcagaaaaa
    18541 tgggatttag aacctgcttt tgttgagtgg ttagaaaaag aaaatgtttt ctgttgtagt
    18601 ttagttgatc gcatcgtccc aggttatcct cgcgaagatg caggtgtttt caatcaacgg
    18661 cataactatg aagatcaatt gatggtcaaa gcagaaccat tcatgctttg ggtgatcgaa
    18721 gggcctaaag aattggagaa tcaactacca ttcaaacagg ctggcttgaa tgtcatcatc
    18781 acagatgata tgactcctta tcgtgaacgt aaggtgcatt tgcttaatgg accgcataca
    18841 gcgatggtcc ctcttgcttt gttggcggaa ttggaaactg tagaagaagt aatgaaagat
    18901 cctttattct ccgcatatgt tgatcagtta ttcaatctag aattgattcc tatgctttct
    18961 ttacctaaag atgaattagc catttatgct gaccaaatca aagaacgttt cttgaatcct
    19021 tttgcccatc acaaattaga agcgatttca ttaaatagtg tttcaaagtt cagcacccgt
    19081 ctgcttccag tgttcaagaa gtatatcgaa gaacaaaatc aggtaccacc gttaatcact
    19141 gtttcactag ctgcgctact tcttatgtat cgaggcgatc aagtaaagcc acatgatgat
    19201 gaaaagacga taagcgaatt tactgatgct tggtctgata atggaacagc tattcctcga
    19261 ttattgcaaa acgctgcgct ttggggagaa gatttgtctc aaataccgaa tgtgacagat
    19321 acagttcaag aaatagctgc aaagatcgat caaaaaggtg tccggtcagt attacaagaa
    19381 atgaaaggaa cgatggtcca tgcttgaaac cctgcaacca acaatgaaat taaatcgacg
    19441 agacagtgtg gtcgtcgcat taacccctat tccaaaacaa acacaactga cgattgatca
    19501 gcaaacgatc accactcttg aagatatccc gcaaggtcat aagattgcat tgggtgattt
    19561 gaaagctgga gacaacgtga tcaaatatgg ctatccaatc ggtcatgtga cgacagacgt
    19621 aactgccggt caatggctgc acactcataa tgtaaaaacc aatctttctg gtgaattgga
    19681 ttatcgatat gaaaaagatg tccatccaag tcattacctt tttgagaacc gaacatttca
    19741 aggttacttg cgaaaaaatg gaaaagtagg gattcgtaat gatttgtttt tagtacctac
    19801 cgttgggtgt gtgaatggca ttgctgaact gatcgtcaaa cagttcaagg aaaaacatcc
    19861 agatctggga cagtttgacc atattacgat tttaaagcat ccttatggct gttcgcagct
    19921 tggaaaagat catcaaaata ctcgagaaat tttagcggac gcagtaaatc atcccaatgc
    19981 cggaggagtt ttagtatttg gattaggttg tgagaacaat acagttcctg aattcaaaaa
    20041 aattttaggt gaatatgatg aagaacgagt gaaatttcta gtggctcaag atgtttacga
    20101 tgagatcgaa caaggtgtgg ctctattaga agagctttta acagcggcgg aaaatgacca
    20161 gcgcatatca gtcccgctct ctaagttgaa tgtcggtttg aaatgcggcg gttctgatgg
    20221 tctatcggga ataactgcta atcctttact tggtgcattt tctgactact tgattgctca
    20281 aggaggcagc acgatcttaa cagaagtgcc agaaatgttt ggcgcagaac aagtattgat
    20341 ggcacgagcg gaaaatgaag aagtttttga ctcaatcgtt gacttgatca atgacttcaa
    20401 acagtatttc ttgtcttacg gggaaccagt ttacgaaaac ccatctcctg gtaataaagc
    20461 aggtgggatc actacattag aagataagtc tttaggctgc acgcaaaaat caggaagctc
    20521 tcctgtcgtt gatgtgctac aatatggcga aaaaatcaga aaaccagggc ttagtttatt
    20581 gcaagctccc gggaatgatc ttgtagctgc ctctgctctt gcttcatccg attgccagtt
    20641 ggtcttgttt accacaggaa gagggactcc gtttggctca tatgtcccaa cggtcaaggt
    20701 atctacgaat acaactcttt ttgaacgcaa aggtcattgg atggatttta atgcaggcgt
    20761 cttattagaa caaccaatgg aagtaatctt agaatcgttt gttcaaaaaa tcatcgctgt
    20821 agctagtgga gaagaaacga aaaatgaaca aaatgacgtt cgagaaattg ccatttttaa
    20881 aaacggagta acactttgat tttcataaaa cagtataaaa agaaagaagg aagatttatg
    20941 tttttatctg atgatttttt attaaaagac gattgggcga aaaagcttta ccattcctac
    21001 gcaaaaaaca tgcccattat tgattatcac tgtcacttag atccaaaaga aatttacgaa
    21061 aacaacaatt tcagcaatct gacagaagct tggttaggag gcgatcatta caaatggcgc
    21121 ttgatgcgag cttgcggcgt gcctgaagaa aaaatcacag gaaatgcttc tgattttgaa
    21181 aaatttttag cttggtgtca aaccgtacca aaaattatcg gaaatccgct ttacagttgg
    21241 tcacatcttg aattgaagcg tttcttcggt attgacttgt tgataaatga agaaaatgca
    21301 gagaaaattt ggacacaagc aaatgaaatt ttggcagctc ctgattttcg ccgtcgggaa
    21361 atcgcaaaaa aatcgaatgt agaagtgatt tgtacaacag atgatcccgc agacgacttg
    21421 cactatcatc agttgcttgc tcatgaagaa ccagatttga aggttctacc ttcattccgt
    21481 ccagataaag cactcaatat tgaaaaagaa ggatttaatg catgggtcac actactggaa
    21541 gaagcagctg accaaacgat caccacctat caagaactga tagaagtctt agggcagcgg
    21601 atagaatact tccatcaaca tggatgtcgt gtttccgacc acgctttaga catcttacgc
    21661 tataaagaag cggatgaaac agtattagaa gagatttttc aaaaagcacg agctaacaaa
    21721 ctattatctt cagatgaaat cgatgcttat cgtacagaaa cactgataca tttgacccac
    21781 ttctatcatt ctcataattg gacgatgcag ctgcacatcc atgcttatcg taactgtaat
    21841 acacaaatgt tggaaaaatt agggcccgat accggctatg atggaatgaa tgatctttct
    21901 ttgactattc ctctgcaaaa attattgaac cgtgcagaag aaacggatca gttgccaaag
    21961 acgatccttt attcattgaa tccgaatgac tatcctgcga ttttagcttt gatgggctgt
    22021 ttccaaaaag aacagaatgg aaaactgcag ttaggttctg gatggtggta caacgatact
    22081 cgagctggta tgcgcgatca attgacacaa tttgctgatg gtagtgcttt ggggaatttt
    22141 gtcggcatgc tgacagattc aagaagtttc ctgtcctaca ctagacatga atatttccgt
    22201 cgtgttcttt gtgaattttt aggcgaaatg gtcatgcgag gagaagcacc tgaagatgaa
    22261 caacttttag gaagtctagt tcaagcgatt agttatacaa atgctaaaaa ttactttggc
    22321 ttttttgcct aattgattaa tagtaacagt aacgaatcaa aaacaggata gtgaaataac
    22381 ggaatccgtt tatccacgtt ttagagaaga agacggacca aatttgctcc gtcttcttct
    22441 cttgctgttc tgcttcattg cctataaacc tttatgaaag aagagataac atgcctacta
    22501 tccatattgc cggtgattct actgcggcag aaaaagatga aaacaagcgt cccgagacag
    22561 gttggggaga aaaaatctct gcttattttt cacccgagat ccagatcaat aaccaagcaa
    22621 agaatggacg cagcaccaaa tcatttatcc aggaaggaag gttagcccgt ctagcttcac
    22681 agtttcagcc gaatgatttc ttatttgtac aatttggaca taacgaccag aaaatccaag
    22741 aagaaagagg tacgcttccc ttcggtagct atttaaaaaa tctgcagata ttttttgaat
    22801 gcgcaaaaaa agcgaacgtc caaatggtct tactgacatc tgtgacgcga cgagattact
    22861 tagaaaacgg aacattgaat ccagatatac ttggagacta tccaaaagcg atgcgtgcat
    22921 ttgctgagaa acaccatatt cctcttttag atgtgttctc aagatcacaa gaattgttcc
    22981 agaccttctc aaaagaagag acaaaaaaat tctacctgca tcttatacct gatacttgta
    23041 aaaattaccc agaaggacta aaagacaata cccactttag tccagaaggc gctgataaag
    23101 ttgcccgaat aattgttgaa ttgataaaag aatcccgtct gcctcttgct aattatttac
    23161 aaaaaggagt ttgagatgtt tccattaaat ttaggcatcc gtgcccacga tttagatgtt
    23221 cgaaatcgtg aagaaatcgt tcaaaaagta tcacagcttc acttgtccca tatccaattt
    23281 gcaccacaaa aagcatttcc tgaacaactt aaattaactg acatgacact tgggagtgct
    23341 gcctattttg gtgaatactt ccaaaaaaac aatatcgaac tttccatttt aggatgctat
    23401 atcaacctat ccagcaaaaa tcaagaagtt cgtgcacaag cattggcaac tttcaaacag
    23461 caaattgctc tgtgctctgc ctatcaagcc aagatgattg ctacggaaac cggtagtgtc
    23521 tctgtcggtt acacaaaaga aaattttact gaagaagctt atcagatcgc cagaaattct
    23581 atcattgaat tagtcgctca tgcagaaaat tttggcgtaa ctgttgctgt tgaagcaggg
    23641 atcaatcatc caatctataa ctatcagtta gctaaacgtt taatcgatga agtagcttca
    23701 ccaaatttaa aaatcatttt agattgtgcg aatttgatgc ataaagaaaa tcatgctgat
    23761 caggaaaaag tgatccgagg tgccttggac aatttacatg gttatattac agcgcttcat
    23821 ctcaaagact atatcatgga aaatggaaag atccgcatgg tacctgttgg caagggctgt
    23881 ttagatttcc gcccggtact gcattatatc aaatatgagc gtcctctaat gtacgccact
    23941 cttgaagcta ctcctgagat ttatgttcct gaagcaatag aacacttgca gtttatttac
    24001 caagattgtt aaggagaaga ttatggagga acgaatacag aaaagttatc aaaaatatca
    24061 tgcaaatgct tttcagacat tgctgcatct ttatcaggga aattattggc gttttgccat
    24121 gtcaggactc ttttttatta tcaaacatct tccatcttgg ttaatgccga tcgctattgc
    24181 caatgtaatc aatgcagctt catcgaaaga ttcttctcag ttgcaggcca tttatttcaa
    24241 cgcttttttg atggcttgtc tgattggtca aaatatattg acgaattatt ttcatgtaaa
    24301 ataccatagc acttcgatcc gtcaagtaga agctggacta agagcgaccc ttatcaagaa
    24361 aatccaagaa ctatctattc cttatcaaaa agaattgcaa tctggacgaa tccagtcaaa
    24421 gatcatccgt gatgtagaag ctatccaaac gttgtcctct caagtatttg tcagcggatt
    24481 aaatatcgct gtcaatttat tcgtagcttt aggtatcacg ctttataaaa gtcctgttgt
    24541 tttcatgttt ttcttattga ctgttcctct cgccgcattc gttactctct ttttccgtaa
    24601 aaggatcaga cagtccaact cagacttcag gcaagaaatg gaagagactt ctgcaaaagt
    24661 gatcgaagtg atcgaattag caccgattgc tcgagctcat gggttagaaa aacacgaaac
    24721 aactcgctta aataagcatt ttactcaaat ctatgaaaaa ggattccact tagatatcct
    24781 gcaatctgtt ttcggatcag tcagctgggc tagttttcag atatttcagc tgatttgttt
    24841 gattttcact gggatattag ctttacaagg gcgcatccaa cccggcgatg tcgtgatgta
    24901 tcagacgtat ttcacgacga tcgtcaattc cgtttctgga atgatcacgc tgattcctac
    24961 gatttcaaaa ggcatggaat ctatcacttc tattggcgaa ctgttgattg ctggcgatgt
    25021 agaaacttat cacggtaaga aaaaaatcca acatttggat ggaaattttc gttttgagga
    25081 tgtttctttt ctttatccgg actcactcaa accgattatc gatcattttt ctctagaggt
    25141 gaaagctgga gaaacaattg cttttgttgg gccatctggc tctggaaaat ctacactcct
    25201 taacttattg attggattta tccagccgac ttcaggaaaa atttttctag atgatcagcc
    25261 tttggatgaa ctggatatgc gaagtgtgcg aaattattta gccgttgttc ctcaaaccac
    25321 tttgttgttc tccgcttcga tcaaagagaa catcacttat ggcttgaaaa acgtatcaaa
    25381 agaacgttta gatgaagtca tcgaagctgc gcaactttct tcactgattg accagcttcc
    25441 tgatggtctg gataccttag taggcgaaca tggcaacaag ctgtctggtg gccaaaagca
    25501 acgtatctcc attgcacgag cgttgatacg tcagccaaaa atcattttgc tagatgaagc
    25561 aacctcagct ttagataacc agtcagagaa aaaaatccag caagccctga attacctgac
    25621 agaaacaccc actactttta ttgtggctca tcggctttca acgatcaaag aggcagataa
    25681 aatcgttgtg atcgatgaag gaaaaatcgt tgaaataggt acttacgaaa aactgttagc
    25741 tcaaaaaggc tatttctacc gcttgaaaaa tgaatgacaa aaaataggag ctatgacaag
    25801 acttttgtcg tagctcctat ttctgaataa acggtgttct cctgccaact cctcggtcac
    25861 aagtcacaat agtcatcaaa catgagaagc tgttttttga aattgttcct tgtaactcag
    25921 agttaaacgg taggctcacg acctcttggt aaatggtgtt caagagacag cctatcggca
    25981 ataagaagca attttgtcat cgctcaaggc cgaacgtctc tttcacaccc tctgttgttt
    26041 cataaaatag ttttattcgc tgtaaaggtc gcgaactggt gtcatgatga tacggttcaa
    26101 gtcattgatg attgtactga agccttgctc tttttgcatc aagtcattga ttacttcttc
    26161 tgattggatt ttcacagcca tttcttgtgc tttcattgca tcttcgtcgc tgaactcttg
    26221 tccactcatt tgtttttctt gtaattcgat ttgcatcgct tggaagtctt tgaacagttt
    26281 gtgtgcttct tcgtttgctt gtactttctc gtacgcttct ttcaacgctt tgaattctgg
    26341 taattcacgg atctcacgtt cgatttgatt cgcgctatcg tagatgtttg acatgttatg
    26401 ccctcttttc ttttagtagt tactctctat tgtaacatgg ggttattcgt tttcaaaggg
    26461 gctactctcc ttgatatttc cgccagaggt ctttagccgc ttcaccaatt ccctgaacgc
    26521 cttctttcac catatcgccg aagtttttca gcccttcttt tgcttgttca ccatattgat
    26581 tcaagttatc ttgccaattt ccagactctc cattagaatt tcctgtgttt ccaacttgat
    26641 ctgcagctac cacttgtcct cctgtggcat aggcatctgc tacactaaat cctgtttttg
    26701 aagtatacgg aaggatgcct tctgccgctg atttgaagac tttcccgaca acatttccac
    26761 ttgtcccttc caaatagtgc agcttgctgg attcttcgta acccatccat gtcgaaatca
    26821 ctacgtctgg cgtgtaaccg atcatccatt ggtcatttgc ttttgtggca tcgaaattag
    26881 tttctgtggc tcctgttttc cctgctatcg tataacctgc aggattcgca gcagccgctg
    26941 ttccatttga aaatgtacca agaagcatgc tggtcatttc atcggctgtt tcctttgata
    27001 tgacctgttt tggttttttg tttgtgttat cgacgatcac cgctccagtc gaatcaacga
    27061 ttttcgtgat aagatgcggc gtatacatct gaccatcatt ggcaaatgca ctgtaagcac
    27121 ccgccatgat caatggagat actccttttt ccagtccacc aagggctaag ccataatact
    27181 tatcagattt tgctaaaggc aggccgaatt cttctgcttt atcatatcct ttttgtaaac
    27241 cgatctcatg caaaagccat acagtaggca aattcaaact ttgtgcaaca gcttgataca
    27301 tcggtacttc tccttggtat gtcccgtcaa aattatgcgc atcgtaataa ctttgcggtt
    27361 cgtctttcaa gatactggaa ggcttgtatc cagcttccag tgctggtgta tatacgctta
    27421 atggtttgat cgttgatcct ggtgaacgac gcatctgtgt agcaaagctg aatcctctaa
    27481 agacatgatc tcctcttcgt cctactagtg cttgtacacc acctgtattc ggatctaaag
    27541 ctactgaagc agattggacc atggcaccat ctgaagcatt tgctgggaat aatgcactgt
    27601 tttgataagt agcttctaat tgcttttgat aatcctgatc taaagctgta tagattttat
    27661 agcctttatt catgacatct tcttcatcaa gaccatactc gttaactgct tcatcgatca
    27721 ctgcatcaaa ataataagga taacgataac cagaatctga attatcgtat gtgtcattaa
    27781 gatacgcgct gatatctgtc tggctttctg cttgttcttg ttcttttgtg atttttccgt
    27841 tttcttccat tacacttagt actgtgtttt tccgatcatt cgcatttttt gggtgatcga
    27901 tcggattata aataccagga cctttcagca ttcctgccaa agtagcagcc tcagacagcg
    27961 taacattcgt tgcatctact ccaaaatact ttctggaagc gtcttggaca ccccataccc
    28021 cgttgccaaa ataggcattg ttaagataca tggtcaagat ttcttctttg ctgtacttct
    28081 tttcgatctc gattgccaaa aataattcct tcgcttttcg atcaaacgtt tggtctaatg
    28141 tcagatacgc atttttggca agctgctgag tgatcgtact tcctccgccc cctgatgttc
    28201 cgccagacaa gaccattcgg actgctgcac gggcaatccc tttgatatca aacccgtgat
    28261 gctcgtaaaa attcctatct tctgtcgaga ttactgcatc ttggatatag ggagaaatcg
    28321 cgtttaattc tacatatgtt cctttttggg cgtacagtgt gccagcttct tcgtttttct
    28381 tatcataaat gactgtcgat tggcttaatc ctgattttaa cgtttcgaca tttgcttgtt
    28441 ttgctaaaat aaagaggtag atacttgtca ctaagacaca gatcaaacca atcagcaaaa
    28501 tcaatttgtt cacatgatat tttttccaga tgcgctttcg ccatcgatgg aattgtccga
    28561 gatatggtct gatccaacgc caaaaactga tcaaagcagc ttttatcttt tctaaaatgc
    28621 tttgaaaatc catttgcttc ttctcctgtc tatttgattc aatcgtctta ttttaccata
    28681 gtgaaagagt gttttcttcc tgcttaagtt gtagttcaat atgttttttt acgttagtgc
    28741 aagtagagta acataagaat gaacagaaaa atgtaagttt tttcttaaat atgttttaaa
    28801 aatggtacaa ttagtctgcg attgcactga aaggagtaca cttgtgaaaa tcacgatcac
    28861 tttacctatg aaccatcctg aaacaacaat tcgcgacttg cttgaaaagg aatggttagt
    28921 tcctagaaag gttcgacact ttttgcgtat acgtaaaaac gtttggatca atcaacaacc
    28981 tgctttgttc catcatgaag taaagggcaa tgaccagatc acattgttat tcgaagaaac
    29041 agattataat tatcaagaag ttcaattagg agatgcgaag cacatccgtg ttttatatga
    29101 agatgagcat ttgattatag tggataagcc tgcaggaatg aagactcatc caaatgaacc
    29161 gacagaaaac agtaccttac tcaatcattt agctgcttat ctcgacacta aacagcaacg
    29221 accttacgtt gtccaccgct tggacaaaga aacaagcggt gccgttttat ttgcaaaaaa
    29281 tccatttgtc ttgccgatac ttggaagaat gttggaacaa aaaatgatct atcggagata
    29341 tcaagccatc gtatggggag aaattgccaa agatatgacc atcaccaata aaattggacg
    29401 agatcgccat gatcggagaa aaagggtcgt agatgataaa aatggtcaga gcgccttgac
    29461 acatgtcact gtcaacaaag tactttctga acaaacacaa gtctattgtg ttttggaaac
    29521 cggacgtaca caccagatca gagttcattt agctcataag ggacatccga tcgttggaga
    29581 ccctctctac caaaatagaa cagctgaacg actgatgctc catgcattag aactgcacat
    29641 gatccatcca tttactcaag aaaaaatagt cggtaaagct ttacctggat tatgggaata
    29701 gaaataaaaa agaacagagt cttatcagca gataatgata agactctgtt ctttttgtgt
    29761 aatttgtctg cttacttttg atgttcgtgt tctgctaaca gcaaactacc gataatccca
    29821 ctttcattcg gcagtcccca acgaacgata tattcactta cttgaggtgt ttccatataa
    29881 ccacccatca attcaacaaa ttgctgacgg attttttgaa ggagatgatc ctgattcatt
    29941 accccaccgc ctaaaataat cttttcaggt gctaacgtca acgtatagtt gatcagtgct
    30001 tgagcaatat aataagcctg aatagcccaa acaggatgat cttgcggcag atcttgccct
    30061 ttgatccctg tgcgtgcctc aatagacggt cctgctgcta atccttctaa acaatcttta
    30121 tgataaggac aagtaccttc ataatggtca tctggatggc gtttcaccca aatatgtccc
    30181 atttcaggat gtgcgatccc tgaaaaaatt tcttcattga tcacgacacc tgcaccgatt
    30241 cctgttccca cggtaaggta aatacaacta ttttttcctt gtgctgctcc ttgcttcaat
    30301 tccccatatg cagcagcatt gacatccgtt gtccaagcag caggaatatt gtagcgttcc
    30361 ttgattgtgc caagaaaatc gaattgtgcc cacccttttt tgggagttgc caaaacgtat
    30421 ccgtaattat cttttgtttt gtcgatacca atcgggccga atgagccaat cccgattccc
    30481 ttcaattcat aacgatcaaa aaattcaaat acctgatcca atgtttcttc tggtgttgtg
    30541 gtagggatac ttaatttttc taaaatttct ccaccatctg aaaccgcaca cacaaatttt
    30601 gttccgcctg cttctattcc gccatacatt cgttttcctc ctcgaatccg attgtccgaa
    30661 tctcataagg ttggattatt gggacaaccg cttgcttcgt tggttcttca agcagattca
    30721 atatgacagt ttttccattg tctttagtta tttccaattt ttctaaatga ctagacatat
    30781 tgaaacctct tactactact ttatcactaa acttgctgcg tttcaaagct gtaattgcaa
    30841 acgtttcact ttttatcgtt aaatattgtt gttttgaaat caatgttcct tcatgatgtt
    30901 tgatttgttg agtggaaaaa ggaatctgtg ctgcgtatgc atgcaaataa gtagagaatt
    30961 tttcttctgg tccatgtagt tcaatgctgt aattgaaccg atgctcacct agacactgtg
    31021 cttctggtgt tggaaaatat ccccaatcgc ctagttctcc cacactgcga agtagcgtca
    31081 ctgcgatttg tccgtcttct gttacttcat attcattcaa accaaagttt ccgactgtta
    31141 caccgtactc ttcatcatga atattgacaa atgcttgctg atgttgcgga ttcgtggggt
    31201 tttcccaact tttagacaca tggtttgggc gcttcaccac ttcaaaaata ctatctgctt
    31261 cgtgatgttc cacatgtaac tttgtaggaa acaagacacg taagcgatga tctttcatct
    31321 gattgtcgag agtcgtttca aagtcgattt ttttactatc ttttctgatt gtcatgattg
    31381 tttttatttg aaggattcgt ttttctttgg atcgttctgc ttttcgataa cgaaattcca
    31441 caaccatctg ctgttctttt tctaaacgct cgtctgcaga aacagggatt tccatttcct
    31501 gtagaatact tatttttgct atttccggtg tatctactaa tacttttact tcagagtttt
    31561 ctttgttact ggataggatt ggctgatcac agaaaggttg tttaaagata tactcatttc
    31621 ctatatcgcc gatatcttca aaaatatgca gattattcaa ctttcgtttg tttttgcgat
    31681 cttccattgt aatggtacca tttttttcaa tcgtcaaatg tagagggccg ttttcgatga
    31741 ttcgtccact ctgatgaatc attgtttcct tttcttctgc tttcgcttcc ccttctacaa
    31801 gcgcgaatgt ttcccaagaa aatgctggca tgttttctaa tggtaaagtc actttgatca
    31861 ttcttgccat atatggcaca cggaaacggt ctttcggcaa atcataacca aattggacag
    31921 tttcttcaga taaaatagct ggtatagtgg ccccactttt tgtttctaca tgatacttac
    31981 gtttaggcaa attttctaac tcttgatata gttgttcagg tattccttca gcgaatcttt
    32041 ttctttctaa ttcgatggtt atttctgctt caccagtttt atccattcct gcagtattta
    32101 caatgacaaa tggaaagctg tcttttggga atccggtcgt atcgattgct gcggtcagct
    32161 gttctaagga atcttgtgca agatactttc caacttcatc tgctttttca aaacgaggta
    32221 tcatttcccg atggacagaa tcgactgaac aaccgcaaat actgtcgtga ggatgatttt
    32281 gcattaatgt cttccaagca taatctaatt gatcatgggg atagtttcca ctaacttcat
    32341 aagccatcgt cgcaagtggt tctgtaatat tttctagctg tcgctggacc ttggtattcc
    32401 attgttttaa gtaaacccga gcagatgctg tattggctaa agtataccag ccatccgttt
    32461 cttgacttgt caattctcct tctactgagc ctaagtcttc tggcacatct ttttgaactg
    32521 cttccagata gtcagtaaaa ttagaatgaa taaactcgta atctggaaac agttcatttg
    32581 cgagatggat tgcttttgat atatcttttt gtaccggttg atgatcaaca ccattcatca
    32641 tcaataagtg gttcgtagag gcatattgtt ctgcatccgc taatttttgc ttccaaaagg
    32701 caagagctgc ttctttttct actggaatct cattcccgtt gctataccaa ttggcaaata
    32761 gcagaccaaa gattgctgtt tgatcaggtc ctttccacca catctctgag tattgggaag
    32821 aatagttttc tgcttccaaa acttgattat caaagccaat tggttttaca ccacggccaa
    32881 acgctgctgc tgaaatacca gcttgtttca ttaattgagg cgtctgtccc atatttccaa
    32941 atgtatcggg aaaatagcct aacatgacag gggttcccca tttacggctt tcttccatgc
    33001 caatcagcat atttctcacg ttcgattccg agctgataag aaaatcatct tgcaagatat
    33061 aaaatggtcc aattctcaat tttccttcat tgattgcttg ttggattgcc tgtctttttt
    33121 ctggccttac ttgaagatag tcatctaaaa taatcgtttg cccatccaaa tgaaaactgt
    33181 tgaaggacgg atcaacttca aatagctcta gtagatcgtc tatcaattca atcagtcgca
    33241 tgtgatgctg ttcgtaagcc atgtaccatt cacgatccca gtggctatga gaaatgatat
    33301 atactttctt tttcatttac gatacctcct acttttctac tctaatatca aagtaatcca
    33361 tgactaattc gcaaaacatc atatttgccc aagaaaacca ttctctcgta taattttcag
    33421 gattgttcac atcgaatcct tcgtgcataa ggtgtgttcc tgcgtcagtt gctacaagta
    33481 aattcaatat ccgctctttt tcagatttgt ctgacgttgt cattccttcc atagctaatg
    33541 caatcggcca aacgtatttt tctggcgtat gggaggatcc aattcctttt gcgtactttc
    33601 cttcatagaa atatggattt tctttactca acaatgttct tcttgtttgc agataatctt
    33661 cctcttgttc agaacaatat cccaagtaag gtgcggcgat cagattgggc acattactgt
    33721 catccatgac tgtggcgttt cccattccat ctacttcata tgcataaatc gtttgccctt
    33781 tttgattaac cgttcgtccg tgattctgaa tcccctcttg gatctctttc ttcaatttct
    33841 gtgtttgctg tacaatttct ttatcatcga gtatcgtttg aaaaatttct tccacataac
    33901 ctaacacgac caccgcaaac atattggatg gtaccagata tccataacgg caagtatcat
    33961 cgctaggacg gaaaccagac catgtcattc ctgtaaaagc tgtttttgca cctcgcccgt
    34021 cattgatcag cgtatcttct tttcttgtcg tgtctcgtac aaatgtataa ggagagtgtt
    34081 catgatcttg ctctgttttg aacacgtcca agattttttt gataccttca ataaaagatt
    34141 gattgaattg atcagttttt cctgtatttt tgtaaagaag ataggccaac tgtattgggt
    34201 agcataaaga atcaatttca tattttcttt cccagatcca atcgttcatt tttgtatgat
    34261 ctgtttggtg gccagcaccg ttagcttctt cgttgaaggc attcgcatat ggatcgatat
    34321 tgatataaaa aaattgcttt ttgactaacc cgctgatcat gtcagctaat tcctcatctt
    34381 cttttgcaat cactaaataa ggacgaactt gtgcagtaga gtctcttaac cacatcgctg
    34441 gaatgtctcc cgtcaataaa aaggtggttc cgtcattttg ctttttgact gttgtcaaca
    34501 gagtattggc aaatgctgct gtaaaattct ttgcccagtc cgcatggata tccccacatt
    34561 tttgtgtgat atcttccata aatttctgca ccgattttgg tatatcttta taagccacta
    34621 ataaaacctt ctttctattt gatatatctt taaagattat acttcataca gccaattatg
    34681 tctacgcttt caaaaaatat ctttttattt actttttcat ccattatggt attatttgaa
    34741 tatgatatat cattaagagg tgtttatatg aatcaaccat tgtaccagac aatatttaat
    34801 gatttgcaaa cggctatttt aactggtgaa ttacctgtag acagccaact accaactgaa
    34861 aaagaacttt cacgtaccta taaagtaagc agaatcactt ccaaacgtgc attgactgaa
    34921 ttagagcaat taggacttat ttatcgcgtt cgcgggaaag gcagtttcgt taaatccgct
    34981 tctccggaac agattcttgc ttctcctaca aaaacacgac ggattctgtt tcttcttcca
    35041 tatgtcgctg atttgtctgt tggtgatttt agcaagggat tgaaccctgt gatgcaagat
    35101 aaacagattg atgtcatgat gacgacgctt gactttctac aaaataaaac agcaaaagag
    35161 ctaatcaatg aatttgacgg attgatttat tatgctcttg atacagaaca acatcttgac
    35221 ttactttttg agctttcatt gaaagaattc cctgtcgtca tattagataa aaaaatctat
    35281 gagttacctt ttcctaccgt tctttccgat aatttccaag gcggtgcgct tgctgcctct
    35341 tatttgatcg aacagggaca ttcaaaaatc gcttatttgt ttggtacgca gactcatcca
    35401 caatccgttc gacagcgtta ccttggttac cttgaagcat tggacaaagc tggtttgact
    35461 ttccacactt cactggatga caaaagcgcg acattagatg aattgctttc ttatatcact
    35521 aagtatgaag taactgcttt tgtttgtgaa aacgatgttg tcgctatcca gaccatgaat
    35581 ctcttgagac agcatggtta tcatatccct gaagattttt caattatcgg atttgatgat
    35641 atccaagcag cagctcttgt tgacccgcca ctgacaacca tcgcacaaga ttttgaacag
    35701 ttaggtaagc ttgcgggaga tgctttggtc acttggttag agacaaaaga tcgaccatcc
    35761 gatagtaaat ttccagtttc attcatcaaa agacaatcaa caaaggagaa ataaaatgaa
    35821 tatcggtcaa atagatacta gacatgcaac agcgaatcag ccaaatttct ctaatgggaa
    35881 ctgccagcct tatactggcg ttccttttgg gatgaattat tttgcaccgc aaactacgga
    35941 tcaaaacggc agctggtggt ttcatcctga tgaccgcgtt tttcaaggct accgtcttac
    36001 ccatcaacca agtccttgga tgggtgattt cagtcatatg ctgtttacgc cgatcaatgg
    36061 aaaactacag gagaacaccc ttttccatgc tcaaagttct taccgcccag aagaaagtat
    36121 attttgcccg actcatctgt cgatctgtca attacgttat ggcatctgtt ctacattgat
    36181 acctagcatg tatggcggaa tcttatctat tgattacagc aaaaatgaca gcggtttact
    36241 tttatccttt ccgggacgcc atcagctctt tgttatagat ccttacacag tggaaggaaa
    36301 aatcacacat tttgctggtt cagaagatcc tgatttttct ttttatttta tattgagatt
    36361 tgaatatcct ttaacaattg atgagttagc tgtttccaac aaaaatagcg actcgatccc
    36421 gttgtatttt gaacagacaa aaaaacaaac tatccgattt gggacatctt ttatcagctc
    36481 ggaacaagca gcttataacc tggaactaga acaaaaccaa agcaaagaga cttaccttgc
    36541 tcacagtcaa gaacaatggc agtcctattt tgatcgtata cagctcacac accatgatca
    36601 acaacaattg cggacgtttt atcataattt atatcgggtg tttttatttc cacaaacatt
    36661 ttatgaaatt gatcctagtg ggcaaaaaat ccactatgat acgactagtc gatctataaa
    36721 acctggtgtt ctctatacaa ataatgggtt ttgggatacg tataaaacgg tttatcctct
    36781 ttattctttg attgctgtag aaaaatacga agaaatgctg gaaggttttt tgaacagcta
    36841 tagagaaagt ggctatttgc caaaatggct gtctcctgat gaacgtggac ttatgcctgg
    36901 gacattgatc gatgcggtca ttgcagatgc tgctgtaaaa gatatccgac gagacttgat
    36961 gcctgaattt ctaacggcaa tggaaaaagg tgctacggtt caaagcaaac atccaaatta
    37021 tggacgccaa ggaacagaag attacttgac atatggctat gttcctaatc actaccacga
    37081 atcagtcaat cacacattag actatgctta tagcgatttt tgtattagcc aagttgccaa
    37141 ggtactagaa gaagaggaaa tgacgaagaa atatcagcag caatcattga actatcaaaa
    37201 tatctttgac tatgagtcag gatttatgcg ttcaaaagat aaagatggca agttcagaga
    37261 accattttca gctaatcgtt ggggacaaga ttatgcagaa ggaagtgctt ggcaaagcag
    37321 ctttgctgtt tatcacgatt tttcaggact gatcggaaaa tatggtggca gtgagagata
    37381 taaagaaaaa ctcattgagc tgtgcaatca gcccccaacg tttgacccag gaggatatgg
    37441 ttttgagatc cacgaaatga gtgagatggc cgcgatagaa tttggacaat tagctatttc
    37501 aaaccagcca agttttcact atccttactt gttcagttat ataggacaac ctgaaatggc
    37561 acagccactg cttaaacagt tgatgactca gaccttcgac gattctccaa tgggttaccc
    37621 tggagatgag gacaatggaa gtatggccgc ttggtatatc ttcaatagtc tgggatttta
    37681 tcctgtcacg cctggaaccg gtgaatatgt tatcggtatg ccattaattg acaaggctgt
    37741 tttgcttttg tcaaatggaa aggaattgac gattgaagca acgcctaatc ggccgcagca
    37801 acaatttatc cataaaatca aacggatgga caaagaatat acgaaattat attttaccca
    37861 tcaagatttg ctgaaaggcg gcacgatctc ttaccaatta gggatcatcc ctcaccctaa
    37921 gaaatatcaa gcaaaagatt tgcctttttc cttatcaaac tataattaac aagaggttgt
    37981 gaaaaagctg tcctgcatca agtaataaga acagccaagc aaaaatagat cctcatattt
    38041 ttcgtttggt tggtcttatt accgcagatg caagcttttg aacaccgttt attgagaggt
    38101 tgtgaaatca gcgttctgac ctgagtatta gagagacaaa tggcaaaata gttcctcata
    38161 ttttgccatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tagtggagag
    38221 gtcgtgaaaa agctgtttag tttcgagtat taagaaaaat tttgtgaaaa tggctttcca
    38281 catttttgca taaatttggc ttaataccga gaaactggct tttgaactcc gtttatcgag
    38341 aggtcatgaa aaagctgcct tgcctcaagt aataagaaca gcccaaaatt agatttctag
    38401 acaatttttt ataagttatt tcattacatt ggctttttct tttatgattc tccactgttt
    38461 tctcggtact ctttagggga tctgccgacg attttcttga ataatttaga gaaatacgtg
    38521 gtgttgttgt agccaatctc acttgctatc tcattgatgt tttgattact gtgcaaaagc
    38581 agttgtttcg ctttttccat acgtaaatgg ttcaaataag ctgaaaaact ttttttcgtt
    38641 tcttttttga acagctgtcc tagatacatg acatttaaat gcaggttttc tgacacttct
    38701 ttgagtgtaa gtggttcttg ataatgctgg tgcaggatta cgattacttt ttccacattg
    38761 tcactgtact ttttctgtct ctgatgcttt ttgatgaatg acagaagtag ctgctgaagt
    38821 tcttgcaccg tttttgcctg atggattttt tcgattcctt gtaaatattc ctcatcttcc
    38881 agatcaatca attcccgttg aatctccata aacagtaaaa aactggaata tcgtatatct
    38941 tccggcatca tggctgctaa ctgaaactgt tcaaaaaaat cagtgatcat tttttgagcg
    39001 acttccaatt gtttattttg cagcacgcgt ctgaaacttg aaaaatcgat ggtttgatct
    39061 tttgtttctg cttgtactgc gtaaaaaaca tgctcgtctt tatctccata aaattgatgc
    39121 aactgtagat tgtctttcgc ttgttggaat gtttcaggga ttttgtccaa agaatctgtc
    39181 tcttccccga tactgatcag ccattcctga tcaggaaagt tttcttgaac aaaacaacag
    39241 aagccatcaa cttcatctgc ctccaacaac aacgtgatca atacacggtc tccgtaattt
    39301 cgttgatagt aaaagatttg ttgccgttct tgcaaccatc tattgataag agtatcatga
    39361 gttcttgcca gttgaatcaa tactatccta tgctgcttct cacttatttg tcctattatt
    39421 tcttcttcac ttatttcatc caattcttca ttcaaccatt gactgaataa cagttcttga
    39481 tagatttctt gttgattttt ttgttcattt tgctgatcta accgtgtttt gattttcttg
    39541 aggctttcaa ccaattcgaa cttattcacg ggtttcatca aataattcac ggcgcctaat
    39601 tgcatacctc ctttcaaata atcgaattct tggtatcctg ataaaatcat aaattcaaaa
    39661 ttatgacgtt ctttttgagc cgcttcaata aattccagtc catttatttc tggcattgtc
    39721 acatccgtta ctactaaatc aatctgtcgc tgttcaagta cagctagtcc ttctttggca
    39781 ttctctgctg ttgctactat ttgaaagcct aaactttgcc aatcaattat cttttttaac
    39841 ccattcaaaa tcatgtattc atcatctacc aataacactt gatacacgct catccctcct
    39901 tgaatgtaat agaaacggtc agtccacctg tctcattatt ctcaagcgac atataataac
    39961 tgctgccgaa gctggcacgt aaacgttcat tcacgttttg cagaccgata gaaccgtgaa
    40021 gttccacttt aggatgagac agtttttctt caatctgttt tagccgtttt tcagtcatcc
    40081 cttttccatt atctttgatg atgatcctta cccgtttgcc ttcctgcaag actttgacac
    40141 ttagcgcatt atcgaatcga gtaaaatcaa taccgtgttt aaaataattt tcaactaatg
    40201 gctggatcac aaatttaggt acttcgatct tttccaaatc aggatcgatc ataaaatgat
    40261 aggctactcg attaggataa cgcatttgat acaaatagac atatttttcg caaaagtcca
    40321 gttcttcttt taaagtgatc gttttctctt gattcgtatt gtttcgaagc aaagcggaaa
    40381 acgcatacac aacatctgct aattcttcac ttccttcgct gattgcatac attcggatat
    40441 attctaatgt attatataaa aagtgtggat tgatctgtgc ttgaagcgcc cgcatatgtg
    40501 cgtcttgctg tttgatttct aatttgtaga tgtcttctac aaactgattg atgctatcca
    40561 acatttcgtt gataccgatt gaaagttcct tcagttcata ttccgtgttt gttatgtcga
    40621 tccgcgtctc taaattccct gctgctgttt gatccatggc ctgcatgacg atagatactt
    40681 gctgtgaata tcgtttgaat gttttataaa gaaagataag cagtatattg tctaaaataa
    40741 tgataccaat gatcagcggg gcaagatttt ttcccgtttc gatttttaca ctttttttat
    40801 ctagtacagc taatatacga taatcatcag acagttcttg gtgttgaaca aaattgtttt
    40861 tttccagatc gtcaatcggc aattgtgaat ttttcttcag actctctgtg atgatcattt
    40921 cttgtctttc aaacgtttct ttagctattt tattatcatg gaatgtgtat agtcgatttg
    40981 tcgttccaga aatcatgtat aaagagagtc cattgaatga cgttagattt tctaaaatca
    41041 tatctagttc tttcttttga aaaccaataa aaatacttcc tgactcagct cctccttgtg
    41101 tgataggcaa cttgatataa aaggcgtcta gtaattttgg tgtccccttt tttatttccc
    41161 cacctttgtt ttctctagaa gattcataat actccggtag ttgattcaac acgatatata
    41221 tcgcacttag ttcttcataa tttgcgtaga gatctttgat ttgatttggg aaagaaacta
    41281 attcatcggt actgttttgc tgttcgtata catacatcag atactgatct atgggttttg
    41341 ttaagtaggt cgtcacattt tcgatctttt cggaattccc tacaagctgg tttttgatga
    41401 tcctactcaa ggttgtttta tcattcagca ttctgcttgt gctttgaacg gcatcacttg
    41461 tcatgttttc tgcctgtttt tgattttgtt cccaagtatg gatactaaaa ataacggtag
    41521 cagtcatcgt tacaccgatc atgataaccg cgtatttccg caacagacga tttagtaagg
    41581 ttccttttga aaatagaatc cgaaacttat tcataacttt ccaactgttt atctaattct
    41641 tcacgccaat gtgttgtcat cgtaccattc caaaccgtca aaagaccaat gacaccaaac
    41701 aggatcaatc ctttgaattg ccaagtcacg cctaaaatta taccgctacc aataattatt
    41761 tttagaaaag acgaaaagct ggaaaaaacc gaaataaaac ttagctttag cagattagga
    41821 acagagatcg tatattcact atctaaaatc atactgtatt gataagtagc aaataggcag
    41881 agcaaggcaa aaagtaaaat aaaatcaata gctaaaaaaa tgagcccttt gatttgaaca
    41941 gataaatata aattgtaact caataaagca gtaccagata aaaataaact aaatagcaga
    42001 ttgcctctta aaaaatttct tttatatata ttccagcctc tttttattgt gatttcttta
    42061 tactcgaatc cgtacaaata aaatagttca ttgactgttt tccatgccgc acctaatcca
    42121 aagatgatcc cgccggcaaa tgtatatatc cagaaataca aggttagttt tataatgacc
    42181 cagatccgga taaataactc ttccaaaacc ttccctaaca tatcttctcc tccaaacatt
    42241 aagtttatac tttctcatta tacaaaaaaa ggttgggcaa tcagcacctt gacctgatta
    42301 ttagagaaac aaacggaaaa atagttcctc atattttgtc gttttgtgag cgaataccga
    42361 gggttagctg attgaacacc gtttaccaag agtttgtgaa atagccgctt agtttcgagt
    42421 agtaagaaaa attttgtgaa tatggctttc cacattttta catatattta gcttaatacc
    42481 gagaaactgg cttttgaaca ccgtttattc ggaacaagag gttgtgacac gtcttttgtc
    42541 acaacccctt tgtctttatt cattattatt cttgtcggaa ctcatcatat tgtttttgca
    42601 tttctttcaa taccttatca tagccagcct tgtccaaagc gtctttcaat ttcggtaatg
    42661 tttcatctgg atcaacagtc cctgtattca atccatctaa atattgattc atgacattag
    42721 aaatattact taattctgtt ttgacactgt cagtgttgaa gctgaatcct aaaatcggtg
    42781 aagtttctgc atcagcaatc gattgatcac gtttggcaat catgtcatcc gtaatagact
    42841 cttgtgtata tagaatcttg ttgtttcctg tattccaagc agacatatgt gtatttggct
    42901 gataaccatc tagcaatttg attttatcat ctgaaccatc gactttttcc catgcttctc
    42961 cctcgatccc ccaaacaagc ccattcaata attctggatc actgttaagc agccctagaa
    43021 gttctactga tttttcttta ttttttgaag tatttgatac gacaaaattt gccatttgtg
    43081 cttgagctgt agattttagt ggaacagtaa ttgcttttga gacaagttct tgttttgctg
    43141 catttgtcaa aattgtatcg ccataatcat acggtccttg tgtttctcca cgcattagcc
    43201 aagtatttcc ttctagtgga taatccttat tgctcgttgc agcgtcactt ggaatgagtc
    43261 cttgtttgta ccagctatgc attgtacgta acagtccgat atacgtttca ttatcgtatt
    43321 ggttgatgat tttcgaatca tctccatcca gatcaatagc aaatggtaac gtattcccta
    43381 aaggataatc aaagttccct tggactttga agccttgtcc aatggcaaaa gctgccgtgt
    43441 ttggttcttt ttcatggaat tccttcaaga ctttttctgc atcagcgtaa gattggattc
    43501 catcaattga aagatcgtat ttatctagta aagctttgtt aaaagtaagt acttgttgag
    43561 caaagacatt tccattgact gggaaagcat ataattttcc attgaccaga tttcctttaa
    43621 tatatgcttc atctaaatca ttataagctt tttcagcgta cttaggcgct aattcagtca
    43681 aatcagcaaa ggctcctttt tgggcattgg aaacatagtt gttcgcaaag gcgatatcat
    43741 aattttcccc ggaagaaatg atgacgttca ttttcttttc gtaatcgccc cagccaatgt
    43801 aattgatatt gacttttaca ccgatctctt tttcgattcg tttgtttgct acttccatca
    43861 attgatcgaa attatctggt ttatctccga tttgatacat ctgcaaagtg tccgaattgc
    43921 tagcttctgc ctggtcttta gaaccagaac ctccgcatgc tgctaatgtt cccaacaaca
    43981 acgctgaaac acctgtaaag gctagtttct tccataactt catttttctt cctcctaatt
    44041 ttatgattta tatttttgtt tctttattct tttactccgc cgattgttag acctttgaca
    44101 aaatgcttct ggaaaaatgg atagctgatc gcaataggca acgtcgagat gactacgatc
    44161 gccattctgg cagattctcc tggaactgag gctaatccgc ctgtcaattg gcttcctgct
    44221 cctgaatttt gtgtcagata ttgaatatta ctttggattt tcatcaaaag atactgtagt
    44281 ggaactagct tatcatcttg gatgtatagt aaagcattga accagtcatt ccagtaaccc
    44341 aatgcggcaa ataaactgat tgtcgcaata cctggaacag ctaacggtaa aacgatctga
    44401 acaaatattc gcagttcgct agctccatcg atccgtgccg attcaataat cgaatcagag
    44461 accgaacgtt taaagaatgt gcgcatcaca ataatattga agggactgac agccattggc
    44521 aagatcaatg cccaaatcgt atcttttaac tgaagaagat ttgtcataac aagataattg
    44581 gccaccatcc ctggtgagaa caacatcgta atcaaacaaa aaacggtaaa aaaacgacgg
    44641 aatggaaagt ttgaccgtga aatcgcataa gcatataaag aagtagccgt gctattgatc
    44701 agtgtaccta aaacagtaac aagtacagtg acgaaaagcg cttggaaaat tttatcctgc
    44761 atctggtcga acaagtacgt ataaccaaat atactgaact tttctggcca aaaactgtac
    44821 ccgtgagtcg acaatatgga ctcatcggta aaagagatgg cgataacaaa tataaatggc
    44881 aaaatacagg aaatagcaaa gagtgcaatc attatattag agaaaaaatt agccgtctta
    44941 ttgaaagagc ggacttggac tctctccact ttcttttttt tcattttttt cctccttaga
    45001 ataatgcaga atcgctatca aaacgtcggg cgatcgtatt tgtgatcatc aacaagacaa
    45061 agccgacaac tgattggtaa agtcctgcag cagccgtcat accaaaatct cctgtggatg
    45121 tcaggccatt gtagatatac gtatccaaaa cttgagtcac atcatataat gcaccggaat
    45181 tcctaggaat gttataaaac aggccaaaat cagctcggaa aatgtttcct acggctaaaa
    45241 tcgttaaaat cgtcattagt ggaataagtt gtggtatcgt cacatgtttg atctgctgcc
    45301 atttgctagc tccatcaacc atagcagctt cataataagt cggatcgatt cccataacag
    45361 atgcaaagta aataatgctg ttataaccaa tccctttcca tgtaccaatg aacaccaaga
    45421 taaacggcca atatttcggt tcattatacc aattgacagc ttctcctcca tgtccagtga
    45481 tccactgatt gaatattcct ttgtcaggac ttaaaaaagc gtaaacaaag taactgataa
    45541 tgacccaaga tagaaaataa ggtagtaagg acatcgtttg ataaacttta acgagtcgtt
    45601 tatttctcaa ctcgctcata atgattgcaa atacgactga gatcagcaga ttcaaaagga
    45661 taaatgctac attatataaa attgtatttt tagtgatgag aaatgcttga tccgaagaaa
    45721 ataaaaattt gaaattttcc caacccaccc aaggactttc cctcaagcta gccaagaacc
    45781 catctgctga aatatgaaaa tttttgaatg ctacgacatt cgccattaca ggtatgtaaa
    45841 agaaaaaaat catccaaagc atacccggta cagccatcag gacaagtgct ttataacgcc
    45901 atagattcat aaaaaaatga ttgaacccct ttcgtttttt catctaaaaa cccctttcga
    45961 ttcattcgca acgtaattat agcgctttca ataatgagaa taaataaaca aagtataggg
    46021 aaaatgaaac aaagtatagg agaggttgtg aaatcagcgt tttggcctga gtattagaga
    46081 aaaaaacggg aaaatagttc ctcatatttt gccgtttttt gagctaatac cgagggtcag
    46141 ctgattgaac accgtttatc agaggttgtg aattcagcgt tttggcctga gtattaggga
    46201 gatcgtgtcc ttactatcta actctgagtc acaaggaaca atggggactg taacaaaagt
    46261 cttgtcacag tcccttattc cgaacaaacg gtgttccaga agtagcttct acggaaataa
    46321 gccgaaattt cacaaaaaag ccatccgaaa gtcagacgga caagtctgct tttcagatgg
    46381 cgctacaact actctgctta ttcttttagc tatccattca attatttttc tctcacttgt
    46441 tctagctctt ctttggtcat gggtcgatat tgccctttat tcaaatcttt aggcagccaa
    46501 aattttccca tacggattct ttttaaatat aagacttctt ttcctactgc tttgaccatt
    46561 cgcttaactt ggtgaaactt tccttcatgc aaaatcagac ggataattga agtttctgtc
    46621 tcttgatcta cttgatcaat ttggagtttt gccggcaatg tctgctcatc gccatcaata
    46681 atcagtcctt ctgcaaataa acggatatct tcttctgtca ttataccgct aacctcagct
    46741 agatattctt tctccacatg ttttttaggt gatagtaact gatgggcaaa caccccgtca
    46801 ttcgttaaaa tcaagaggcc ctctgtgtct ttatctaatc ggccgactgg aaaaagatct
    46861 tcccgataat cctggtcttc caataaatcg attacggttt gatcatgatt atcctgagta
    46921 gcagaaatga ctcctgcagg tttatgcaaa atgtagtaaa aatctttttg atacgtaatg
    46981 atttctccta aataagtaac cgcatcttcg aattcattta cttgcgcttt atcgcttttc
    47041 accacttgtc cattgacttc gatcgttcct tttttgatta atcctttgac ttctttgcgg
    47101 ctgccaagtc ccatatctgc taaaaactta tctaaacgca tgcgtttccc ccatttcaaa
    47161 agagcatcaa tctagctctt ctgattcact tattttattt ttaatttatg tcgtaaacgc
    47221 gctattcctg gtcctagtag tctttctgcc aagcggattt tcaaagctaa ataaccatac
    47281 actaaagccc ctatacctgc tactacaaga atcaacaata gagactggaa tttgctatct
    47341 tcgtttaaaa aagcaccaaa aatcatcttt gtgatccacg aagccaaaag cataatcaag
    47401 gtaagaataa agatcagcaa tgtcctgcgc cagacaaaac ttggtttaaa gcgggctact
    47461 tcatggattc tctttaagat caaggtacaa gacacagcaa atccgatcat tgtcgccaat
    47521 aaagggccgt atacttcaaa taaacgaatg gctgggtatt gaagaaggag tttcactaga
    47581 aacccaataa ccaaataatt aattgccgcc ttgttttcaa acattccttg cagcatgttg
    47641 gaaactagca tatatagtcc taggaagagt cctacaaaac ttgcttggat cagtacatta
    47701 cttcctagag aatccggtgt ataaaataat gtatttagcg gataggcaag taacataaca
    47761 ccaaatgtcg ccggaaacat aaaaaatgaa aacaactgta aatttccgct tgtcaatttt
    47821 gccagaccta ctcgatcttt caacgtaaca gcttctgtaa tcaacggtaa cccagtagac
    47881 gcgatcgatg ttgccaatgc aataactacc atcgtcaact tatctggatt ggcactaaaa
    47941 atcgaaaaaa gatccagtaa ctgtgcattg gaatactcgg tggatgcaga catgatcttc
    48001 ataaaagtga actgatcgac taatttgaag atcgttaccc ctgaacccac aataataaac
    48061 ggaatcgctt ctttaacggt atctaacaac aattccttcg ttgcaatatt tattttgttt
    48121 tcgctgtagt gaataaacgc cgatgtatac gcttgatgtt tcttcaaaaa atacaaaagg
    48181 acaagaatac ttgctagcat accgataaat gccgcgaaag ttgattgcgt gaccgccgtc
    48241 acatagtcac catccatgac tttcatgatg atgaatgtag ccaatagcat ataaaaaata
    48301 cgtgccacct gttctacaat ctgcgacagc gcataaggca tcatttcttg attgccttgc
    48361 aaataccctc gtatcacact catacaagga aaaaccaata cagcgatact caaagaacgc
    48421 atcgttggaa tcagttcttc tccgccacca gaagcatgag ctagccaagg agaggcgatg
    48481 tacatgaaca aagcaaacaa caggcctaac ccgcccatca tctgtaatgc acggataaat
    48541 aatcgtcgtg aagtgccata ttcattcaat gaattatagc gtgcagtttg ttttgcaatc
    48601 gcagcaggta ttcctgctgt agagatcagt agaaacaatg catatatatt gtatcccata
    48661 ttgaataatc cattggcagc cttagcattt tcgcccatcc aagcatacca gggaatgata
    48721 tagacagcgc ctagcaatct tgaaatgata ttactggcgg tcatccaagc agagcctcgt
    48781 gccatttttt cttgcggtgt taattgatct aatgctggtt ttctttgatt atccatcggt
    48841 cagattccaa ctttctacaa aacattacta tcattttaat tggtaaaaca gaaactggca
    48901 atcgatttta tataactttt ataagaacaa ttgttttttt gaattcggtt tcgttttttt
    48961 ggtaaagtaa agaaatatac agccttttat ggctaacatt tataggagat atcaatgaca
    49021 caagaaataa aaaaactacc cgttatattt ttaggtcttt tctttatcac agttggattg
    49081 aattggttct tgctccctca cgatatagct tccgccggag tgggcgccat cggacattta
    49141 gttgaaacgg ccttttctat ccaacgctca gttactgttt ggagcatcaa tcttatgatg
    49201 ctgcttctag ccgctgtcct attaggaaaa tcagtatttt ttaagactgt agcgggaagt
    49261 ctgctttttc ctgttgtttt agagattgtt ccaaaagtgg aaatgatctc ctcacatttc
    49321 ttttcactga tttcaggaag tcttttgttc agtcttgggg tttacacatt gtacacagtc
    49381 ggggcctcaa atggcggtat aacgataccg ccgattattt tccacaaatt ttttcggctt
    49441 ccaatgccgc aaggactttt acttaccaat agtcttatcg tctttttgaa ttattatgtt
    49501 tttggattgt tggagacact attcgttctc ctatctatta cagtcagttc attgtttatg
    49561 aaaatactca tccgcttgtc ccctgtgtca agaaaatttg aataaagctg gattttgtca
    49621 tagcggaaac aaacgatata ttaaaaagag tgtgctataa taaaccaaga aattgaataa
    49681 agcgagggat caatcaatga gcttctcttt agaagacatc cgtcatttac tattaaaaga
    49741 aaatctatta aaagaatttg tttcaacaag aggctggcat cttgatgtac cagaaaaagc
    49801 tgaatttctt cagttaagtt atgattcaag aaaagctgat gcttctactt tgtttttctg
    49861 taaaggaatg aatttcaaag aagaatattt ggattcagca atcgaacagg gtattcaata
    49921 ttatgtatca gaacaaccat acgaaaattc agcagtagga atcatcgtaa cggatatccg
    49981 taaagcaatg gcgcttcttg ctatggcttt ttacgactat ccgcaaaata aattgaaagt
    50041 gatcggattc actggaacaa aaggtaaaac aactgctgcg tactttacaa aagcaatctt
    50101 ggatcacaca acaaataaaa aaacagcatt gctttctact atgaatacaa cgttagatgg
    50161 caaaacatat ttcaaatccc atttgacaac gcctgagtca ttagatttat atcgtatgat
    50221 gtcagaagca gttgaaaatg gtatgactca tctagtgatg gaagtttctt cacaagctta
    50281 caaaacacaa cgcgtatacg gcttgacttt agatgtcgga atcttcttga atatctcgcc
    50341 tgaccatatc agtccgatcg aacatccgac atttgatgac tatttctatt gcaagcgaca
    50401 attgatcttg aattcaaaaa cagttgtttt aaatcatgaa agtgactatt ttgatttact
    50461 tagggaaaca gccgatctat tccagattcc aacgatcact tatggtcgtt cggaagaaag
    50521 caattatcaa gtgatccgtt cagataaagg tactcacggt tttactttat cttctcatga
    50581 agatcgctta gctatctgcg atactgctta tgatattttg ctggctggag gattcaacca
    50641 agaaaatgca gccagtgcga tcattgccgc agcactaaca ggtgcctcca gtcaagatgc
    50701 acaagacgga ttaaaagaag ctcgtgtacc aggccgaatg gatcaattga tccaatccaa
    50761 tggagcgcat gtctatgtgg actatgcaca taattatcta agcttgaaaa cattgctgaa
    50821 atttgccaaa aatgaacatc cagatggccg tgtaattgtt gtattaggca gcccaggaaa
    50881 caaagcaatc tcccgtcgac atgattttgg aaaagtgcta tcagaaacag ctgacatcgc
    50941 ctttttgacg gcagatgacc cagcatttga agatccgaaa aaaatcgcgg aagaaatcaa
    51001 tgaagcaatt actaatccag atttgatcgt tcattatgaa atggatcgtc ctgaagcgat
    51061 tcgacgcgct ttagcagaaa gcgctccgca agattcagtc gttattgcgg gaaaaggcgt
    51121 ggatccctat caaaaaatca atggtgtaga tgaaccttat gaaggggatt atgcaatcgt
    51181 gaagcggttg attgaagaat aatggtattt atatactagt ggtttcccat ttctaagaaa
    51241 aaaagggact gtgatttttt gtcacagttc cttttttctt agaaatcatt ttaacttttc
    51301 actagctaat tctgctgcct tttctctttc ttcatttaat aatttattat catagaattt
    51361 gataaatggg aaccagataa tgaatgcgat gattgcacaa atgactgcta acacagcagc
    51421 tttccaatca ccaccactac caacaaatgc tccgatcccg actggtgaag gccacggcat
    51481 ctgtgcaagc atcggtttga cgatttccag ccgaatggca aaataagcga gtgtagcaga
    51541 agccatcgga gctaagaaaa acggaaccgc taaataggga ttgtagacga ttggcatccc
    51601 gaaaatgatt ggttcattga tattgaataa tcctggtaca agtgaggctt ttcctaacac
    51661 tttcagctga tcagatttcg cgaggaatgc aataaagatg atcaatccta aagtcgcacc
    51721 tgatccacca acggttacat aagaattgtt gaattctcct gccaacggat aatttgcgcc
    51781 ttgtgcgtta gctgccatat tagctaatac gatcggggtc aagaaagaag tgatgatatt
    51841 cgctccatgg atccctacga tccacaatgc atggatcaag aaataaatca ccatgacacc
    51901 aagccatgta ttcgtcaact gcgtaacaaa cccaaatggg atagcaatca ttttgaagat
    51961 atccgttcct agtgcaacta ataatccatt gatgatcatc accacaaacg caatgacaaa
    52021 tgttgggatc agagcagtga aagaacgaga aactcctggc ggaacaacat ctggcatttt
    52081 tatgacccaa tttctcttga cacacataca atacaattcg accgcaataa tcgacataat
    52141 aatagctgta aagattcctg aagttcctaa acgttcgaca aaagagccca tcctaatacc
    52201 atttactaca gtttctgtct cattgataga agcaatcaag ctgattttac catcagtcat
    52261 gatcaattca gggatacaca taaagaatgc aaaaacagat agtaatgccc ccgtgagcgg
    52321 attaacattt aatttttgtt catctcgttc aattgacgtt aattcataag caaacacaat
    52381 ggcaaagtaa atagataaaa tccccatcgt cattgtattg acgatcatgt acaagtcact
    52441 aactttgaaa aaagttgcat taaaaaatcc ttctaaaaat gggaacggta atggcaaaat
    52501 atttaaaacc aaaaacatcg agcctacaat cgtgaaagga atagaagcca tccccgctgc
    52561 catgacagcc cgaacgattt taagttgcgc aattttcccc ataggtccca tcaggtattt
    52621 ctgcaaaaaa tcaaacatta gttattctcc tttcctaaat ataacgcttt ttcatattgt
    52681 ttaatacgga tatactgttg gtcttggttg agtgaaattt tctttaaacg atactgtata
    52741 aatgcactgg caaaaatacc gcttacaaca agaatgaaaa caaataactg tcctccattg
    52801 ttatttgcca taaaaggata caagaatgta aatcctgagg taaacaacac tggaatcact
    52861 aataaattaa agacactctg gaacaaaaaa taccactttg tccatggaac gttcgtttgg
    52921 tgttttcgat aaagctttac ttgttctcct actgcaggca aaatagctaa aatcagaatc
    52981 atcggtaaac tacttcctaa acttttagct gatagaagca gaatcatcca ttgcatgttc
    53041 atgaaaaaga aaaaggcagt caggtaacgt acgattagat aacgattgaa atacatgttt
    53101 ttcaaactaa gttgcttttt ttctaattcg attttccttt ttactgtatc ctgcacaatg
    53161 atccttcctt tctatttatt tttttgatac aaataattca tttcctgtgc aacttccaat
    53221 aatgtcatcg tcgtcatcag atgatcttgt gcatggacca tgataatttc catttctatt
    53281 tttgtcccgc tggcatattc tttcagaagt tgagtttgtg actgatgcgc atgaagaatc
    53341 tcttcatttg cttgtcgcaa cttctcttct acttcttcaa acatctcttt acgcatcgag
    53401 cgaaatgctt catgtatcag tgtccgtgca tttccgctat ggaaaatgat atcaaaagaa
    53461 gtcacttgta gtgtttcact gtttattttt tcagccatct gttttcctcc ttattcgatc
    53521 agtttgataa atttactgct gaaattctca aaaataggtt cagctaagat ttcctgctgt
    53581 acttttagct ggtcaactaa cctaacgatt gctttagtca cgaccgtaat tccttcattt
    53641 tcgacataag aaggcgaaac taaaaaaaca aaatgaattt cttgatattg atcccactgc
    53701 atcccagaag gaatcaatgc aacggctacc tttgtttcga ttccaactgg aacagcggga
    53761 tgtgggactg ccactgtatc actgaatatg atttgtccca tattttcacg ttgctggatc
    53821 tgctttcgca tttctcttat atatccttct tcttcattta tgctcagctt ttgcagcaaa
    53881 tcatgaagaa tttcttcctt tttcggttcg tacgtataag tcttgaaaaa tttttcagac
    53941 aactgttcgg tgtaaatctg ctttttttgc tgtagagaaa atgctggtat cggtctatct
    54001 gaggaatgat agggtataga ttctccaact acctttcgta ttttacgaac atcatcttca
    54061 ttcaaaaaaa tactgacatg taaaactgga attttgaaaa acattgtcga aagatcaata
    54121 gaagaaataa tcaggtcgat tccttttaaa gttgtttcat tgatctcata atagcctttt
    54181 acacttacca ctgtaatatt tttaccgaat tcactgacta cgcgattctt taatagttgg
    54241 gcactgccgt aacccgttgc acagataatc aatgcatgta gtttatgcgc agctctttct
    54301 ttttccaatg ccgccatgag atgcaaagcc aaataggccc attcatcttc attgatggta
    54361 tagtttttca aagccggcat gttgctgaaa tgccttttta ctgcgtcaaa gactttggga
    54421 ttttctttct ttatctcctc agtcaatggg ttctcaatgc gaatacctcg gctcaatcga
    54481 atcatcatcg gtgacaaatg atcgagtagt ccattgaaaa gctggagatc ctctactaat
    54541 gaaaaatgaa attcctgaga caatcttttc agaactttcg ctaattcctt tgatagttcc
    54601 tgatcatttt gattttcttt gtgattcgac ttagccatga gatgtaatgt caaataagca
    54661 atttcttctt cgggaaacga tacacctgcg attacctcaa tacgttgaac gatccgctgc
    54721 gccacttgat actctactcg cttagaaact tcttgttcga tgcctaattc cttgatttca
    54781 aacccttctc ggagccgttt gatccccaaa gccaagtgta aagtcagatt ctgtatgata
    54841 aaatccgaaa cttttaactt agcttctctt gtttcatcga gaatgataat gactagctct
    54901 tcaaaactga tgtctgggaa aaaacggctt tgccctaaat attctttcaa tgaatttcca
    54961 taatggtttc caaaaaaagt atccatgata aaatgccgtc gatttctttc ttccccttcg
    55021 atccatgtcc cttgaccatg cttagaaacg atttttagtg aatatggaat caatcgctcc
    55081 ttgatttctt gcatgtcctt tgtcaaactg gaacgactga tataaagctc ttctgccaaa
    55141 tcatccataa aaagaatggc atcttccaaa agcaattggt tcaatatata cttttgtcga
    55201 tcttcggact cataaaatcc ttgcggttct ctagcatatc caggtactat ttcttgccga
    55261 ctcaaaaaca agtcaaatgt cagtctttgt aaaatatgca gttggtagcc ataacctggt
    55321 ttagcaatga tcttacctcc gtttttttct actaactctt tgatccgctg caagtaatta
    55381 cggattgtcc gatcagataa taacaattca gaagctaaac gttgactggt gacatactcc
    55441 ttcttgtgat caatcaaata tctcaacagc aatttttcct tctgtttcat tatcatccac
    55501 tcctattcca tcatatgttc tcttcgatca cctctgctaa cttctggatg cctgtaggga
    55561 ttgggacata cgcttggaaa gggatactaa caacaggctt tccaacagat tctcctaatt
    55621 ttttgaattt atccaaaaac atcgtcgttt gcgggctgat cagaaataaa tcaaaatcac
    55681 tattcttaat catattatcg ccttctgtag ctgaaactgc atctacgagt acctcttctc
    55741 ttttttgctt aaagaaatcc gttgtctttg aggccatcat cgaggatgac attcctgccg
    55801 cacaaataat caatgctttt ttcataaatc aatcactcct tttattttta taaaccaagc
    55861 atatcttgta agcgttttct attcaaaata tatatttccg tagcattgcg gaaaaaatgt
    55921 gtatcatatc ttgaataata atttctggca ccgtgatata ctagtgatag aattttttca
    55981 ggaggggatt tagtgagtat cacagtgaat attttgtata caagtacaaa tggacaagcc
    56041 agaaaatttg cagaagaaat ggtcgaaaga aacattgtca aagcgattcg tgcagaagaa
    56101 ggaaacgaga aatatgacta ttactttcca ctagaagatc cagaatctct tttactgatc
    56161 gaccgttgga aagatgaaga agcaatcgaa aagcatcaca aatccgaaat gatggctcaa
    56221 ataaacgaac tccgtaaaaa gtataaatta aaaatgaaag tcgaacgttt cactgattta
    56281 ccgtaaaaag atacacatgg aatgatagca atttatcatc catgtgtatc ttcacttttt
    56341 ccttattttt tattcgatct catctaatga ttcaaaccgt gtttttctct tatttttcgg
    56401 ataagtattt cagtcacccc aatatacatg attcctaaac ataccccaag gatattctca
    56461 aaaatgcgga tcgttactgc tcctggaacc ccgaataaac tggcagtgat tgccaaagca
    56521 ccaaaagaat taaaaactgt tttatatcta taggtagaac aaacacctaa agctagacca
    56581 cctaatatac cgacccagtt aaaaggaata aattggctga taccaataaa taaaacacat
    56641 ccaatcaatg agccaatgat tcggtctact gctcgttctt tgaaaccaat cgacatcaat
    56701 ccatagctag atacaataga agaaaatgca aaccctgccc acatcaatcg ctgaaaaggg
    56761 acatactctc ctgcaacgat caaaagacta atgccaaatg catagatgag catccaaatt
    56821 ttttcctgcg aatacatgcc tttcaaaaaa atctctttaa acaagctttt gtctttgttc
    56881 ttttctcgat gttttctgta aaggagaact gaaaaccaac aaaaaaacaa aaataataag
    56941 ctacttgttt gtgtaaagaa attcttgttc aacgaatctt taggtaacga ataaacaata
    57001 aagagatatg aaaagccgta caaagaagca ttccccattt tgggatcact agcggttgcc
    57061 attaatatgc tgcttagtaa aataaaatga atcaacatgc ccataactga ccatttgatc
    57121 agctggacat acggtgctac taatagtgag aacatgacga ttgctaaacc tatgatcgaa
    57181 tgggaaatct tataaccaaa gtcaacaaaa cgaatactca tcaacataca gaataaaacc
    57241 acagcgtatg gtttatgctt cgattcaaat aatgttgtaa ttataatgat aaaacaaatg
    57301 gcaaacaata cgatgaataa tgatcgtaaa aacaatgaac aaatatacat gcacttttct
    57361 tttttagaag ctgcttctcg tattttttgt tttaaaataa acggatctag ttgtagagac
    57421 tgataaaaat ccacctgttg tcgtcctttc tttttacttt tattttttac agtcatctat
    57481 gacaggttgt aaatactatg gaacatcata tggcgttgtc attttcttgt caactatttt
    57541 tcctattcat gtttttataa aaaaacatat cgttttcttg tatgattaaa tcaccacaaa
    57601 ataaacaact gagagaacga tatgctttat gaatggttct atcaaaaaaa ttctgagatc
    57661 aatagacaaa aatttgatga ttacagaggt ctcttacgaa accttacaga agaaaaaaac
    57721 attgatcgtt gctgcagttc tcttccctgc tccatgtgtc tgtagaaatt gtggttctgc
    57781 tgtggtagat ggaaatagga aattaatggt ggtgaaaaac aagaagaagg aaaccattgt
    57841 ccactttgaa taatataatc atatgccaat ggttatacgc ctaaaaaagc agcgctatac
    57901 ctgtaaaaac tgtcgaagcc attggaacgc tcaaagttat tttatccgtc caaggcactc
    57961 gatttcaaat catgtcagac ataaaatcac ttctttactg actgaaaaag tgtcgttatt
    58021 ttttatttcg aaaagttgtt aggtatcttt gacaaccgtt attcgcacat tgaaagagtt
    58081 gagaagctat ttaccaaagt cttccaaaag aattctgtct tgagtgttga gggttgtgaa
    58141 tttcgttctc acgtttccgt tgaggataaa ctgagtttta tttccgcgga tggcgagaca
    58201 gaaaaattaa tcgagaaaat ttacctacac aaaaaattcc tcgattaaca aactatttcc
    58261 ttagctgcac taatcctaaa gaaatagaat tcttagttac agacatgaac gccacctact
    58321 ttcagctcac caaacatgtt ctaccaaatg cgaaattggt gattgatcga ttacttggtt
    58381 tttccacgcc tttcaaggag gcgtaacctt tattcacgag ttggttgaag ctttccgaga
    58441 caaaagaccc gacttgtttt tctccttatt gacaaagagc cattaaaact agagaaaaaa
    58501 ttacaactga tcgctgatta tttgtagaaa gaaaatcaaa gtattaccca ataaacttga
    58561 gtcattaggc aaaaaacact gcgaaactca agaatgattt tcgcagtgtt tttgtatatt
    58621 ttttattaac tagtattact acaaaggttt atttttcact tctcaacgca gcacaaaatt
    58681 gtctttactt atttactggt tgggttcaac cttctctact ccgatactaa tatttgtttg
    58741 tatacccctt ctaaaatcgg tagtttccat tcaattgatg ggtactagtt gattttaaaa
    58801 actatgctta ttcaattttt tattttagct catatatttc gtttctttct aaattttata
    58861 ctgatgaaaa caagtagcac acccaatatt gacaatataa actggctaat gatggtttct
    58921 ccagtttttg gaagatgctt atttccactg cttgttggat tgtttcctct tatatctgag
    58981 ctatcagcaa cttttctatt ctcttttgtt aaaaagatcg ccacttcttg ttctttttcg
    59041 atcttgaaag ttactggtgt cgcatccaat tcataccccg ttggcgcttg agtttctacc
    59101 agctgatatg ctcctggtgc taagccatct atcgccagtt ttccatctgc tcctgtggtt
    59161 agacctgact gcagaacggt tccattggca tcttgtaact caaaaacagc tccttgcagg
    59221 acttctccgc tttggtcatc gatctttgtc aacacgacac cgcctggtgt aagtcgattt
    59281 tctttcgtca attctaccac cgctgtctga cttctttcga tctcaaactc gattggtgtc
    59341 gcatccaatt cataccccgt tggcgcttgg gtttctacca gctgatacac tcctggtgct
    59401 aagccgtcaa tcgccagttt tccatctgct cctgtggtta gacctgactg cagaacggtt
    59461 ccattggcat cttgtaactc aaaaacagct ccttgcagga cttccccgct ttggtcatcg
    59521 atctttgtca acacgacacc gcctggtgta agtcggtttg ctttcgtcaa ttctaccacc
    59581 gctgtctgac ttctttcgat ctcaaactcg atcggtgtcg catctaattc atacccc
//
LOCUS       DACBZK010000007        56361 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.007, whole genome shotgun sequence.
ACCESSION   DACBZK010000007 DACBZK010000000
VERSION     DACBZK010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.007"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            303..1148
                     /locus_tag="IVD66_000508"
     CDS             303..1148
                     /locus_tag="IVD66_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP6144756.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1429..2649
                     /locus_tag="IVD66_000509"
     CDS             1429..2649
                     /locus_tag="IVD66_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HAP6144757.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2646..5366
                     /locus_tag="IVD66_000510"
     CDS             2646..5366
                     /locus_tag="IVD66_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6144758.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5350..6294
                     /locus_tag="IVD66_000511"
     CDS             5350..6294
                     /locus_tag="IVD66_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP6144759.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6363..7373)
                     /locus_tag="IVD66_000512"
     CDS             complement(6363..7373)
                     /locus_tag="IVD66_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP6144760.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7553..7897)
                     /locus_tag="IVD66_000513"
     CDS             complement(7553..7897)
                     /locus_tag="IVD66_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAP6144761.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7890..8324)
                     /locus_tag="IVD66_000514"
     CDS             complement(7890..8324)
                     /locus_tag="IVD66_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HAP6144762.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8462..9199
                     /locus_tag="IVD66_000515"
     CDS             8462..9199
                     /locus_tag="IVD66_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6144763.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9192..10403
                     /locus_tag="IVD66_000516"
     CDS             9192..10403
                     /locus_tag="IVD66_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6144764.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10610..11389
                     /locus_tag="IVD66_000517"
     CDS             10610..11389
                     /locus_tag="IVD66_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HAP6144765.1"
                     /translation="MEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAAL
                     SREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLKT
                     MLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHGD
                     VNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDEM
                     LEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11459..12121
                     /gene="trmB"
                     /locus_tag="IVD66_000518"
     CDS             11459..12121
                     /gene="trmB"
                     /locus_tag="IVD66_000518"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HAP6144766.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12219..13974)
                     /gene="ade"
                     /locus_tag="IVD66_000519"
                     /pseudo
     CDS             complement(12219..13974)
                     /gene="ade"
                     /locus_tag="IVD66_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
     gene            14106..15035
                     /gene="cpaF"
                     /locus_tag="IVD66_000520"
     CDS             14106..15035
                     /gene="cpaF"
                     /locus_tag="IVD66_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAP6144767.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            14992..16041
                     /locus_tag="IVD66_000521"
     CDS             14992..16041
                     /locus_tag="IVD66_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HAP6144768.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16038..16316
                     /locus_tag="IVD66_000522"
     CDS             16038..16316
                     /locus_tag="IVD66_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAP6144769.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16291..16761
                     /locus_tag="IVD66_000523"
     CDS             16291..16761
                     /locus_tag="IVD66_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HAP6144770.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16778..17080
                     /locus_tag="IVD66_000524"
     CDS             16778..17080
                     /locus_tag="IVD66_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144771.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17097..17468
                     /locus_tag="IVD66_000525"
     CDS             17097..17468
                     /locus_tag="IVD66_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HAP6144772.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17440..17799
                     /locus_tag="IVD66_000526"
     CDS             17440..17799
                     /locus_tag="IVD66_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144773.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17971..18978
                     /locus_tag="IVD66_000527"
     CDS             17971..18978
                     /locus_tag="IVD66_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP6144774.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19003..20187
                     /locus_tag="IVD66_000528"
     CDS             19003..20187
                     /locus_tag="IVD66_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HAP6144775.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTMMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20624..22207)
                     /locus_tag="IVD66_000529"
     CDS             complement(20624..22207)
                     /locus_tag="IVD66_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP6144776.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22785..22928)
                     /locus_tag="IVD66_000530"
     CDS             complement(22785..22928)
                     /locus_tag="IVD66_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HAP6144777.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23151..23630)
                     /locus_tag="IVD66_000531"
     CDS             complement(23151..23630)
                     /locus_tag="IVD66_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP6144778.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23703..23987)
                     /locus_tag="IVD66_000532"
     CDS             complement(23703..23987)
                     /locus_tag="IVD66_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144779.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24065..24259)
                     /gene="ssrS"
                     /locus_tag="IVD66_000533"
     ncRNA           complement(24065..24259)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="IVD66_000533"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24331..25617)
                     /locus_tag="IVD66_000534"
     CDS             complement(24331..25617)
                     /locus_tag="IVD66_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HAP6144780.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKSAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25755..26426
                     /locus_tag="IVD66_000535"
     CDS             25755..26426
                     /locus_tag="IVD66_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HAP6144781.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26392..26880
                     /locus_tag="IVD66_000536"
     CDS             26392..26880
                     /locus_tag="IVD66_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HAP6144782.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26893..27840
                     /gene="prmA"
                     /locus_tag="IVD66_000537"
     CDS             26893..27840
                     /gene="prmA"
                     /locus_tag="IVD66_000537"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HAP6144783.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27841..28605
                     /locus_tag="IVD66_000538"
     CDS             27841..28605
                     /locus_tag="IVD66_000538"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HAP6144784.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28838..31051
                     /locus_tag="IVD66_000539"
     CDS             28838..31051
                     /locus_tag="IVD66_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HAP6144785.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31062..31508
                     /locus_tag="IVD66_000540"
     CDS             31062..31508
                     /locus_tag="IVD66_000540"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HAP6144786.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31679..32938
                     /locus_tag="IVD66_000541"
     CDS             31679..32938
                     /locus_tag="IVD66_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HAP6144787.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33027..33974)
                     /locus_tag="IVD66_000542"
     CDS             complement(33027..33974)
                     /locus_tag="IVD66_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAP6144788.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34368..35660
                     /locus_tag="IVD66_000543"
     CDS             34368..35660
                     /locus_tag="IVD66_000543"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HAP6144789.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35675..37444
                     /gene="aspS"
                     /locus_tag="IVD66_000544"
     CDS             35675..37444
                     /gene="aspS"
                     /locus_tag="IVD66_000544"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HAP6144790.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37553..38428
                     /locus_tag="IVD66_000545"
     CDS             37553..38428
                     /locus_tag="IVD66_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP6144791.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38694..40577
                     /locus_tag="IVD66_000546"
     CDS             38694..40577
                     /locus_tag="IVD66_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAP6144792.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40652..40936)
                     /locus_tag="IVD66_000547"
     CDS             complement(40652..40936)
                     /locus_tag="IVD66_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAP6144793.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40926..41660)
                     /locus_tag="IVD66_000548"
     CDS             complement(40926..41660)
                     /locus_tag="IVD66_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HAP6144794.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41789..42412
                     /locus_tag="IVD66_000549"
     CDS             41789..42412
                     /locus_tag="IVD66_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HAP6144795.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42604..43725
                     /locus_tag="IVD66_000550"
     CDS             42604..43725
                     /locus_tag="IVD66_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HAP6144796.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43732..46860
                     /locus_tag="IVD66_000551"
     CDS             43732..46860
                     /locus_tag="IVD66_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HAP6144797.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46879..50073
                     /locus_tag="IVD66_000552"
     CDS             46879..50073
                     /locus_tag="IVD66_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP6144798.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50219..50926)
                     /locus_tag="IVD66_000553"
     CDS             complement(50219..50926)
                     /locus_tag="IVD66_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAP6144799.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51691..52089
                     /gene="spxA"
                     /locus_tag="IVD66_000554"
     CDS             51691..52089
                     /gene="spxA"
                     /locus_tag="IVD66_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HAP6144800.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            52421..53074
                     /locus_tag="IVD66_000555"
     CDS             52421..53074
                     /locus_tag="IVD66_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HAP6144801.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            53300..54298
                     /locus_tag="IVD66_000556"
     CDS             53300..54298
                     /locus_tag="IVD66_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HAP6144802.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            54474..56282
                     /gene="pepF"
                     /locus_tag="IVD66_000557"
     CDS             54474..56282
                     /gene="pepF"
                     /locus_tag="IVD66_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HAP6144803.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        18539 a         9725 c        11681 g        16416 t
ORIGIN      
        1 tcatcttttt ttgtttaaat cttttgctaa gttgaactaa tagagtcttt tatgaatatc
       61 gaagttagtt tttcacctaa cttcgttttt tatagttggt tattataaaa tagtaatata
      121 gctgatttgg attcaattca tatttattta taaatcaaaa atacagagaa tagtatataa
      181 atgtcctttc ctattcttaa aatgatgttt gtacttactt aaattaggta taattagtat
      241 atgttttgtg agaaatttag acttacaata agcagtgaat ttataatcaa cgtataggag
      301 acatggatga aatgaaacta attggtatag atttagacgg tactcttttg aattctgacc
      361 agagcattag tcaaaaaaat gcaagaacaa tgaaacattt accggaagac tgttttccat
      421 tcatttgttc tggaagagaa gtagaagaca ttaataatat tctcaaaaaa tctggtttaa
      481 ggataccagc agtagggtta aatggttctg ttggatttga tggagaaaaa aagatatttg
      541 agtcttcctt cgataaaaat gatgtaaaaa aaattgattc tgtcctatcg aaatttccaa
      601 ccaaaatata tacaaatctc ggaagttatg aatctcagaa ttataaaaat aaaatgaaaa
      661 aaatttttca cgaggtaggg agtgaatttt ctatcaaaga gctaaactat gagcttgagt
      721 atgaaaaatc tatttgttca atcccttata ataatattga ggaaattata gaaaaggatg
      781 ctatcagcat ttacaaattt tttattttta ttcctaatcg tcaattgaaa gctaatatat
      841 ttaaccattt gaaaaagatg ctaaatgtgt ctgttactga atcggcacct gtaaatattg
      901 aaatcgtacc tcaaaatgta tctaaaggtg tggtgtttga tcgtttggaa tcaatctaca
      961 atttaaagaa acctttgaga atcgcgatcg gagatagttt aaatgactta tctatgtttg
     1021 aaagtgcaga tattagtttt gcaatgggaa atagtcatca agaaatcatg aaaaaagctg
     1081 attatgtcac tgtttcaaat gataaagacg gagtatctca agcatttgaa agaattctta
     1141 ccatataaac taattaaggt agtatagaac atagaattct aaatacggaa aaatggagca
     1201 taaattccag tacaaatagt acttcttcag tgtcaaacga agcgaatata acatagatat
     1261 ttaggattgt gacaaaaatc atgtcacaat ctttttttcg aataaactta ttttttgaag
     1321 tcggccattt atcgtaattt ctttgcataa tacgaacaaa ttttcggtta ttgatgaaaa
     1381 aaaacattga aaatggtatg ataaaagaaa aaaaggagga aatttttaat ggtgaaattt
     1441 atccatgcgg cagatttaca tatggatcgg tcatttgaag gactgacaac tcttgataaa
     1501 actgtacagg aaaaactatt gaagacgaat ctgaccgttt tatcaaatat cattgaacag
     1561 gcaataataa ataacgttga ttttgtttta cttgcaggag ataattttca tcaaaatcgt
     1621 ccttcattaa aaatacagaa acatttttca gaacagatga aacggttaga aaagaaccat
     1681 atacctgtat ttataatatt cggaaatcat gatttctatc aaaaagagcg gtattggttc
     1741 tcctttccta aaaatgtcca tttatttaca tccgaaacgg tagagacaaa aaaaataacg
     1801 ataaaaagtg gagaaactgt ctctctcagt ggatttagtt atcgtcaacc gtggattcaa
     1861 aaagacaaag tgatggaatt tccttctaga gaactcacag attaccatat tgggttgtac
     1921 cacggggaac ctggcgtctc tcaaaaagga aactatgctc ctttccaacc ctcaaagatg
     1981 caagaaaagg gatacgatta ttgggcttta gggcatatcc atgtgccaac ggtcttaaat
     2041 gaaaagcaaa caattgttta tccaggtgcg cctcaaggtc atactaaaaa ggaacaagct
     2101 tctacatcta ttctactagt tgaattaagt aaaggaagtt gccaaataca tccgattaaa
     2161 gtagcagagg tctattggaa gacaaaggaa atatcattga ggaaagcaag aacgacaaaa
     2221 gaggtcattg ttcacattcg tcagcagctt tcaaaagtag aggatggatt tagtttaatt
     2281 gagataaaat taaaagatta tgaccatctc aatacagatg ttttggaacg gatacaatca
     2341 ggagagctat tagactattt gttagaggaa ttctcagata ggataaatga tttctttatt
     2401 tggcgtattt ctctcataga gaatactttt tatacgaaga ccccacttgc tgcttctgct
     2461 aaattgatgg aacagttatt tcaatactat cagacacctc aagatttcca acaaatttta
     2521 aatgaagtat atagtcatca agaagcggct agaatattga gcgaactgcc ggaatatcaa
     2581 gaagaaacac ttgaaaaagc caagcagctg cttaatcaag attttttatt tgaggaggat
     2641 caggaatgaa gattttaagg atcgagattg ctgcttttgg aaaatggcgt caaaaaagtt
     2701 ttgactttta ttcaggcaat cagctgatct atgggggaaa cgaagcagga aaatcaacga
     2761 tttatcaatt tattcaagca atattatttg gtttcccttc aaaaggccgt aaaaaaaagg
     2821 attatacacc aaaagacggc tcagcctatg gcggcaaaat atggcttaaa catcctgtat
     2881 atggtgaatt tgctgtcgag cgctacaagc agcaaaatcg cggaaaatcg aaggtgtggc
     2941 tgggggatca agtgggaagt gatgagttac tagaaaaact gatcgcacct ttgacgaaag
     3001 agttattcca gcaggtattt actttccagc aagagcagtt gatggaacta gatcatttga
     3061 gagaaaaaga gctacatgat gcgctgattt ctttaggcat cacgggcagt tctcaagtat
     3121 tccaaaagcg gcaagaatat tatcagaaag cacaacaatt attcaagaaa aaaggccaaa
     3181 aattactaat caatcaaaaa ttaaatgaat ggaaagagct gcaagaaaaa attcatcaaa
     3241 aacaagaaca ggaagcttat tttggcaagt tgatccaaca agaacaggaa tacgagtcgc
     3301 aacagcagca gttattggca caattaaaag aggcgaacaa acaattttca ttagccagac
     3361 agcaagaact taatttttct ttatatgaag aatggcaatc tctcaaaaaa aacagcacta
     3421 caggtcttcc tgatgagcaa cttcttttag atctggagtc tttctccaaa cggtatcagc
     3481 aaacaaatga gcgtttggaa gaattagaag caacactgga aaagcatagc gggatggatc
     3541 agcagtcagc cagatattat ttttatttag agcaggagca ggaactaaaa gatctccagc
     3601 aacttcaatt tacagcggaa caattaaacg aagaatggca aagattacaa attgagacta
     3661 gagaaacaaa ttcagaattg aagattttgg aacaaaggtg gcattggcag aaaaatccgt
     3721 taccggaaga atttttatat gaagaagaat ggaagcatct tctggctgaa gaaagaagga
     3781 ttgctgatct agaaagccag atttctgtgc gtctccaaat agctaaagaa cagcaagaga
     3841 tgattgaagc agaagtgaat gacttggaag agacctatcc agcattatta caaaatcagt
     3901 cagagatagc accagtctct tcatctaaac cgtatatgct gatggctggc ggagcaataa
     3961 tcattgcagg tatatttgta ccaatgccct tgaaagtgat ccttttacta attggtgcag
     4021 gcatgattgg ctatttcttc tacaaaaggc aaccaaaaat taaaactaaa aatgatttct
     4081 ctgagataaa aggaatgtgg caagaaaaac taggacaact tgatctagcc ttagctcaat
     4141 tagctgaagc agaagaaaaa caaaagagaa ctggagaaga aaaacagatt cttcagcaag
     4201 aagtatatcg ttttgcggat catcggcact taggaaagat ggatacgctc aaactcatga
     4261 aagaatatgg acaggaagtc atagattatc agaaattata tggcgtattt gagcggaaac
     4321 ataaaagaga acaggaaata caagaaaaac tacgacaaat cgaccaaaaa tttgagtttg
     4381 ttaaagaatg gttaccgata caagataaga caatttcaga aaaaatggta ttgctttccc
     4441 gttttataca agagatggaa cagatgaaat ttgccagaag ctatcagcaa aatactttat
     4501 tgaagcaaga aatcaatcaa ttgaaaaaga aacaaaaagt atggatacaa gaatacagcg
     4561 aacaattgac tcaagcaggc ttatcttatc cttcggaagt acctgtcttt ttacaaaaag
     4621 ccaaacaagc cgaacagcag atgaaaagat acaatgaatt atcggaaatg cttactccac
     4681 tatttcctga agagctgaca aaagagaaat tatctgtaag actgcgccaa ctgaaagaaa
     4741 agcaatccca actccagcaa gaagaaaaag aagcaagtga aaatcggcaa cgactccaac
     4801 ttcaagtaga agagttgcaa agagacggca cattggacga actttatcaa caagctagcc
     4861 ggcaaaaagc aaaattacag gaattactgg aggaatgggg agcacttgaa atcgccggga
     4921 cattcttagg tgatctttca acagagatga gtgaaagaca attaccccag ttgttaagag
     4981 cagcaggtga ttatttaggt attttaacaa aaggaaatta tcagaagata ttactgaaaa
     5041 atgatacact gactttaaca gacggatata cagaatttcc catctatgag ttatctacag
     5101 gtacgaaaga tcagctgatt atggcgatga gatttgctta cctctcatta gaagctaacc
     5161 gttcgatatg cccgatcatc attgatgatg gctggcttca ttatgatcat cagcgaaagt
     5221 atcaattagc tgaactttta gctaaatttg gagaaaagta tcaaataatt tgtttttctt
     5281 ctgataaaga aatggtaagc tattaccatg agatgaacca aatcgtaaaa caattagaag
     5341 gagcaaataa tgaaaaaaat tcgtgattta gtaatcgatg agcagtttga acaatttgtc
     5401 ctgatcaaaa gtgcagatgt aagaatcgct aaaaacggaa aaaaatttat tgcttttact
     5461 ttccaagata cttcaggtac tatcgatggt aaatactggg atgcttcgga ggaggaaatc
     5521 aataaattta cagccggcac agtcgttttt ctaaacggta aaagagaggt ttatcaagga
     5581 aaccctcaag taaagattct tcatatgcgc ttaacaaggg tagatgagcc aggagagcct
     5641 agtttataca tggaaagagc ccctttgaag aaagaagaaa tggaagaaga aatcaatcaa
     5701 ttgttgtttg agatcaccaa tgcgcattgg aatcgtattg ttcgctatct acttaataaa
     5761 tatcaaaaac aattttttga gtttccggca gcaaaaagaa accatcatgc atttgccagt
     5821 ggattagctt atcatacttt gacaatgctt cacttaggga aatcaatcgc cgatgaatat
     5881 cctgagctga atcgagcatt gttgtatgct ggtatcattt tgcatgattt aggaaaggtg
     5941 attgaacttt ccggtcctat gtcgacagaa tatacgcttg caggaaattt gatcggtcat
     6001 ctggtattga ttgacgaaga aataactaaa gcctgtcttg cgttgaaaat cagcgaagct
     6061 gacgaagatg ttctcgtatt acgtcatatg gttttagcac accatggctt attagaatat
     6121 ggctcacctg tacgtccaag aataatggaa gcagaaatat tacatcaaat cgacaatatc
     6181 gatgcttcga tgcagatgat gttgacttcg attcgtcaaa cagaaccagg aaaatacacc
     6241 gatcggattt tcggtatgga caaccgaagt ttctatgtac caaaagattt atagcaaaat
     6301 tttatttttt tcattcaaaa caaaaaaagc gagacataag tcttcgcttt ttttgttttc
     6361 ttttattttg atgaatcagt tgtttcttca gttgaagatt cttttgttga atcagttgat
     6421 tttgtgtcag aactctttgt tgaagctgta gtttcacttg agtctttcgt acttgatgaa
     6481 gttgttgtga atgcactcaa cacattttca aaggcatcat ctttgatttt tacatttgca
     6541 tcttttaatt cttcaccgat tactttagtt gtgaatgcat tgtcacttag tttagtttca
     6601 gtagcgatat cttttagttg atctttgtat ttatccatgt cattgccttt attttggttt
     6661 ttcaccattt tgacaacgta gtattctgtc gcataagaag taggatttgt tgtagtaata
     6721 acatcggaga tctcaccgtc tttcaatttg aaagctgctt cttttacttc tgcaggaata
     6781 gttgttgtcg ttgagtcgaa tttaacttta ccgccatctt cttttgtctc tgtatcagtt
     6841 gatttgtctt tggctaattt agagaaatca tctccatcat ccgctgattt tttcacatct
     6901 tttgcttcat cttcacttga taatttgatg atttgtgctt ctacttctgg atggaaagat
     6961 ttccaagcag ttttcaaatc gtcatctgta atatctacgt gagctttcaa gccagcttca
     7021 aaagctaaat tgttacgaat atattcttta taagtatctt tcgtatatcc agcagcttct
     7081 aattgtgatt caaaagtatc acctaatgat ttcgcttgtt tgtcgtattc tgcatccact
     7141 tgcttatcgg ttactttatc gccatatttg ttattgaata ctttataaat gatcatccgt
     7201 tgtactaagg attggttcga tgattcaagt tttgcttcat catagaaatc agatacagtg
     7261 atcgttccgc ctttcatcgt tgcgatatct ttattagtat cgcctgaaca agctgctaga
     7321 gttaaaacag ccaacgcact agtagctgcc aaaataattg attttttttt cattaaaatt
     7381 tgcactcctg taattagtta ttatttttat atattaacta taccatatcc catttccttt
     7441 aaaaacgttg tcgtggtagt ttcaaacaaa attcaaaatt tcatcacatt cctaggaaat
     7501 acgcaaactt ttctcactta tatagttaaa tctgttgaga aaataatcat tattatattt
     7561 gttcaggata ctctggcaga tcagctttta gtttttctac ttgttcattg atttgtgtga
     7621 tacgtggttc ggcttggaat ttaaaatctt cgatatcttt tttgattgct tcttggaaag
     7681 caggaatcac agattcagct gtttcttttg tttcgatcaa tgcgctttta aaatgattca
     7741 ggctgttatt taaatcattt gtcagagttg ttgcttcttc caattcttcg atcagtttct
     7801 ttcttgtttc attcccgctc ctgggcgcca ataacagacc tccgacagtg ccagcagcag
     7861 ctccaaataa cagtcctttg aaaaagtttt taatcatcgc aggacacctg ctttacgatt
     7921 gtttcttgaa tagcttttag ttcttccgat ccataactat cttgatgatt gacaaagtga
     7981 atagaaaaat catcctcttt gctgtagcga gggactaaat ggatatgtga atgaaaaaca
     8041 gattgatagg ctagttcacg gttgttattc aagatattaa gacctttcat ttctggaaaa
     8101 gctttttcca atgcttgagc aatcttaggc acacgcgaaa aaacctctcc tgcaagttcg
     8161 ggatcatatt caaaaatatc tgctacatga cgtttaggca caactaatgt gtgtcctttc
     8221 gttgcttgag agatgtctaa aaaagcatag accttgtcgt cttcatatat tttatagctt
     8281 gggatttctt gattgatgat tttgcaaaaa atacagtttt ccatataaaa catcctttct
     8341 ataaagaata aatacttcag cttaacttta ccataagtta aagctattgt aaggaaaaaa
     8401 acaaaatacc gtcattttct tcgtggtata ataaataaaa ataaatggcg gaggaaaaag
     8461 aatgagttta attatcgatc atgtcacagg ggggtacgga catctccctg tgttaaaaga
     8521 tatcagtttc gatgtacagc ctggagagat agtagggttg attggactga acggagcagg
     8581 gaaaagtacg accatcaagc acattatcgg tctgctggaa gcttcaaaag gaacgataga
     8641 aatcaatcat ctatccttaa agaaaaatac ggaagaatat cgcaaacaaa ttgggtatat
     8701 tccagagact ccttctttat atgaagaatt gacattgaga gaacatatcg aagtcactgc
     8761 gatggcctac gatataccta tggatatagc aatgaaaaga gcagaaaagt tgttggagac
     8821 ttttcggtta tctaatcgtc ttgactggtt cccagctaat ttttcaaagg gaatgaaaca
     8881 gaaagtgatg atcttatgcg cctttttgat cgagccttct ttatatatca tcgacgaacc
     8941 atttttaggc ttggatccac tagctatcaa tgcattgctt gaattgatgg tagaaatgaa
     9001 aaaagaagga gccggtattt tgatgtctac gcatatttta gctactgcag aaaaatattg
     9061 tgatcgtttt gtggtcttac ataacggaga gatacgagca gacggttctc ttgagatgtt
     9121 gagaaaagaa tttcagctgc cggattcttc tttggacgaa atctatattg ctttaacaaa
     9181 ggagcaggca catgagtagt ttttttcaaa aacgtttagc aagacatcaa aagaaaatga
     9241 tgaaatatat gcgttatgta ttgaacgatc attttgtttt agtttgtctt ttcttgattg
     9301 gcggtgtggg attatattat tctaattggt tgaaaaccct gcagccaccg tttgcaattg
     9361 gagggctcat aatctctgta ttttggatgc tctgtttatt cgtgggtaag atggctactt
     9421 ttgcagaggc agcagatatt gtttttttac ttcctaaaga aaaagaaatg caaacctatt
     9481 tggaacgagc ttttcgctat tcttgcattt ttccgttgat ctttttgata ttggcatgcg
     9541 gattggccat gccattagtg gtggttagta cggagcaatc cttttcgatg tttttcgtct
     9601 atctgatcat attatggagt ttgaaattca gtcatctgca aatcaagaga gcagaattgt
     9661 ttcgactaga tcaacaagtt attcgttatt ggaaattagg ctggtttttt tcttctctga
     9721 tctttttgtt tctatcattt tattggctaa tatgggcagg aatagcaggt gcattagtac
     9781 aggcaagtct atattactgg tttttgtgga agcaacaaga aaaaggattg gattgggaga
     9841 aaatggtgca tgtagaagaa cataggttgc atcagatcta tcaatttatc aatttattca
     9901 cagatgttcc tgaaattacg gcaaagatca aaagaagacg ctatttggat cctatattga
     9961 ctcatattaa aagagaatca aaaaacactt atctttactt gtttgcaaga agattggcaa
    10021 gaggttctga ttttagtggt ctttatttcc gattagtaat tataggtggg ttattgattg
    10081 ccggagtagt cgacttttat tttagtctga ttatcggttt cttattttta tatttgatcg
    10141 gtttccaact gttaccttta gcgaaccagt tccgctatat ggttctcgtt cagctttatc
    10201 caatccataa gaatcagaag aagcaggcga ttcagtatct actcacatgg gtattaatta
    10261 tcgcgtcggt tatttttggt ttgattgctg cagtcgtatt agatgggcag cagcgatggg
    10321 ttccgctagc ggcttatttg attgttacta tgctctttgt taaactatat gtaccaactc
    10381 gtttgaagaa gatgtcagac tgaaaacaaa gctgtgtagg gtaaaaatga gaatgaaaaa
    10441 tagagcgttg acagtaagaa tgctgttcgt tctatttttt ttgagaaaag ctggtttttt
    10501 gaatggcaat taaatgaaaa agaacgtata tgtgcttgac gtgtagtgtt caggcgacta
    10561 gaataataag tactgcaaaa caaagagtaa gaggacggga gaatgcatga tggagtttca
    10621 gttagaccaa gagtggcggt tacgtcccat caaaggcgac acaggaaaaa catacatagg
    10681 catgcgtgat gaggacaaag tctttattaa acgaaacacg actccgatgt tggctgctct
    10741 ttcaagggaa ggaattacac caaaacttgt ttggacaaaa cgaacgggga atggcgatac
    10801 tttgacagca caagagtggc tggaaggtcg cttgctgact cctaatgaga ttggtcaaag
    10861 aaacgacgtg attgatgttt tgtaccattt acatcattca aattctctta aaaccatgct
    10921 gacccgtatc ggtggtcgtg tcatgacgcc ggagaagatg ctgcaaaaat atgaaaaaga
    10981 attaccggaa gaactccaga aaaatcaatt tctgcaaatt gtccatcgtt ttcttcgtga
    11041 gcagatcccg tcaatagata aggaaaactt atcagtagta cacggagatg taaaccatcg
    11101 taattggtta gtatgtaaaa attatttata tctagtcgat tgggattcaa tcatgtttgc
    11161 agaccctgcg gtggatattg caacgatttt aggaaattat gtgccactgt ctagctggaa
    11221 tcagtggctg atcagttatg gcatacgccc gactgacgaa atgcttgaaa aatttcattg
    11281 gtatgcggcc atgaatttgc tccaagaaat caccagatat tgcaaacgtg aagatcatcg
    11341 acggatgaac gaagaaattt tacaattaaa acgaattttc agtggctgag gtttggccca
    11401 aactctgcgg agatttggcc agaccttttt aattagagga aaggaatgga gataaataat
    11461 gcgtgtccga aatcgtccgg gagcagcgga aatgttagcg gctcacccga attttgtaat
    11521 tagtgatcca acattgtgga agggaaaatg gaatgaattg tttgaaaacg atcatccaat
    11581 ccacattgag attggtatgg ggaaaggcca gttcatcact ggaatggcaa aagcccatcc
    11641 tgaaatcaat tatattggag tagaaatgca ggtcagtgtt gtttcgattg cactagacaa
    11701 gttgatcgaa caaccgcttc ctaacctgaa acttctacat gtggatggat cagcgttgac
    11761 agagtatttc gctgacagcg aagtagatca aatctatctg aatttttccg atccatggcc
    11821 aaaaaaacgt catgaaaaac ggcgattgac atataagact tttcttgctg tagatgaaca
    11881 gattcttcgt ccaaatggag aaatccattt caaaacagat aatcaaggat tgtttgagta
    11941 ttctctggca agtttttctc aatatggcat gatcctcaaa caggtatggt tagatttaca
    12001 tcaaagtcaa tttgaaggca atattatgac ggagtatgaa gaaaaatttt cttcaaaagg
    12061 tcaacgtatt tatcgagtag aagctcaatt tcaagataag accaaaaaga aaagtctgtg
    12121 aaactaactt tctgctttca taaaaacatt aatatccata aataaatccc agaaaatgaa
    12181 cattacagat gtaatgtatt ttctgggatt tatttgattt aaaatgtatt tatttcatcg
    12241 gtttttccac aaggtggaat caattggaag cgagaaaatg aaaataatcc tttgtcggtg
    12301 atcttcaatt cgggtatgac agataatgtt aagaaagaaa gtgtcaaaaa aggatcaaag
    12361 gttttagctg ctcctagttg atgtgcttta gttattaatt cattcaactg ttcatagacg
    12421 atcgaaaaag gttcctgtgt catgattccg cctataggaa gagaaacaca agctatttcc
    12481 tgctgtttgt tgacaacggt catcccgcca cctttttgaa tcaaaagatt agcagcatac
    12541 agcatatcct cgtcgtttgt cccaacgaca actagattat gcgagtcatg ggcaatcgtt
    12601 gtcgctatcg ctccttgttt cagctgaaat cctttcacta tgcctaatcc aatgtttccc
    12661 gtttgatggt gacgctcgat caccgcaatc tttaattggt ctttttcgat tgaaggaatg
    12721 aatcgttcgc cttgtcggtc cactttttct accaaatctt tagtcactag actattcggg
    12781 ataatttcga tcacatgggc ttgtgaagaa gaaagaagca gctctaacga atgtggattt
    12841 aatggttgag cgtttagttt tggcagacaa cacgtatatg aatttgaatg atcagcaaat
    12901 aaatggtctt ggagttgccc agattgaaca actaatgttc ccttatagaa aacttcatga
    12961 attggcagct tggtaagatc gtctgttaag aagaaatcag cttgataccc aggggcaatc
    13021 gcacctagtg ttttcaaatc aaaacattct gctgcattca atgttgccat ctgaatggct
    13081 tgtaatggat cgattccaag tgcaatagct tgacggacga tatgatcgat tgatccttct
    13141 tttactaaat cattgatcag tttatcatcg gtgacaaaga agcatcttct tgaattttca
    13201 ggtgtgatcg ccggtagtag cgatgccaga tcttttgcaa cggtcccttc tcgaaccatt
    13261 aaatacatac caagatccaa acgttcttta gcttcttttg cagttgtagc ttcatgatcc
    13321 gtccgaatac ctgctgcagg ataaacattt aactcttcca tgccgatacc agctgcatgc
    13381 ccgtcaattt ttttcttatg ctggtgcatc aattggatct tttctaggat gtctgtttca
    13441 ttatttgcta ctgcttgata gttcatgact tcagctaagc ctaaaacttc gggtttttgt
    13501 aaaaaagggg ctaatttttt tgcatttaaa tttgcaccat tggtctcaaa aggggttaca
    13561 ggtacacaag aaggtagcat aaaaaagata ttcatgagtg tttgtcttgc atcttctatc
    13621 ataaactcaa gacctgtact cccagcaatg tttcctattt catggggatc tgtcactaca
    13681 gtagtaactc catgaagcaa ggatactttt gaaaattcgc ttggtgataa aagtgagctt
    13741 tcgatatgca catggccatc gatgaatcct ggcactagat attgcccatt agcattatgt
    13801 acggcttttt ccttcgtatt caccgattcc tacgatcatt ccttcgcaga ttgctacatc
    13861 tttttccatg atttctttcg taaagacgtt gacgatctta gcatgcttga tcactaggtc
    13921 agcaggcttt tttttacttg ctacttcgat atatttcctt aatgttgttt ccaatggagt
    13981 gcctcccaag ataaattttt ataagtataa cataaattcg gtttttgcca atattttttt
    14041 gtaaattcat tttatttgaa acaaaaagat caaaaagacg tatgtttttt gtggagggga
    14101 gaataatgga aataaaacga ttatcggatc aaatgataag tgaaagtttt gccaaacatg
    14161 cccaagacgt atatatattg ccagcttcag aagtatttta catctatttt cgctatggaa
    14221 aaaaacgaac attctggaag aaagtctctt cggcagatgg acagcaactg atctcaagat
    14281 ttaagtattt gggacagatg gatatcggag aaaaaagaaa agctcagtta ggtgcattta
    14341 cttattcttt agaaaaacag gaagttcgtc tgcggttgtc ttctgtagga gattaccttc
    14401 aacgagagag tttagtgatt cggctattat acggtacttt tgaaacaccc catcgttgct
    14461 ttagttctcg agattttgca actattttac agaaaaccgt cagacgtgga ttataccttt
    14521 tcagcggacc agtcggatca ggcaagactt ctctaatgta tcggttggct ttggaagaaa
    14581 aattgcaagt gattactatc gaagatcctg tagagataga agaaccgttt tttctgcagc
    14641 tacagatcaa tccgaaaata gcacagactt atgatacact tttgagactc gcattacggc
    14701 atcgtccaga cttgctaatc attggcgaga taagagatga atcaactgca catgctgcgg
    14761 taagagcagc actaacaggg caccgggttt ttgcaaccgt acatgcacgc aatcttgaag
    14821 gtacattggt cagaatccat gaactgacaa agaaaaaaga agagctatct gaatgtttag
    14881 ctggtgtcat ttatcaagaa cttttggaag atgccaatca ccatccttct gttttatgga
    14941 gttatcaatt tatggaggaa gaatcagtaa aaaaatcatg ggaggaaagt tatgaagaag
    15001 ctcaggaaaa tatttggcag tcagaactat tctaaaggat taacaagaag ccagcaaaac
    15061 cagtttgcac aaaccatggg agaactgctt ttatctggtt ttagtctgca agaatccctt
    15121 tatttattac tcacgatccg ttcgtttcca cctgttattt tggcaaatat ccaacatcag
    15181 ctaaaggaag ggcaagcgtt tagtgaggta ctttcgcaaa taggatatgg agcagagcaa
    15241 ctggtacaga tcgagttagc tgaacgtcat gggaatctgc cgacaacttt gttggaaatt
    15301 gccaaacagt ttcggcttgt tgaaggattt cgcaatgatt tgaaaaagct gcttgcatat
    15361 ccgatgctat tgctcacctt tttgctaggt atcttgttta gtatgcggtt gttcgttttg
    15421 cctcagctta ttggttcagg aatggtcatg caagagcatt ggggtattca gctgatacaa
    15481 gtctttcatt ggtatgttct actattcatc ctagcggtta ctctattggc tttactagta
    15541 aggtatcgtc tgatgaagtt gtctcctgtt gatcagagtg aatggataag cagacaatta
    15601 ttgattggac cgatatattc cttgtatcaa tcggcttatt tgtcactaga gattggaaag
    15661 ctttttcatg aaggtttcga attaaggcaa atcatagtct gcttaaagga aacgaaacaa
    15721 gaaagtctga ttcagcatct tgcctctaag ttgattcaag gattggaggc aggtatgtca
    15781 ttggctgagc agttccagaa ttatcgtttt ctatcagaag aattcagtaa aattgtttta
    15841 cagggagagg caaagggaag tttaggtaaa gaactgattt tttacagcga atggacaaga
    15901 aaacagcttt tcaaacgtct tcatcactgg atgcatttta ttcagccaat catttttttg
    15961 ggcgtagcgg ctttgatttt attagtttat gccgctgttt tattacctgt ttacggaagc
    16021 atagaggagg ttttgccatg aaaaagagaa aaatatctta ttatagcggt tttacattga
    16081 tcgaaatgct aatcgtctta ctgatcatca gtgtattagt gttgttgttc gtccctaatt
    16141 tgtcgcgtta taggaatcat gtagaccaag aaagtcgtga agcgatcatc cagttggtag
    16201 acacacaaaa agagctctat gcgcttcaaa ataatggaag agttcctact gtggaggaat
    16261 tgttgaatga aggctatatc aaacgagaac atgcagaaat ctatcagcgg ccttgaaggt
    16321 aaggttttag catcaggata tacgttgttt gaatcactct tactgatttt attacttaca
    16381 acgatccttt cttttccagt tctcgcattt tctgcatgga agaatgaatt ggcagtctat
    16441 caatttttcg gccaatttga aaaacgaatc tattctacgc aaaaaatcgc tattgtgaat
    16501 cagatccaaa caggctttta ttggaatagt gaagagaatc aaatcatttt tcatgttccg
    16561 aatccagata aaataaattg ggaagtatta gatattcctg atgagattac cttgaaacgc
    16621 catgcttcta ttacttttgc tgctagaacc gggaatgaaa gttcactaaa agcttatcaa
    16681 ttttattggg aagaaaaaga gcggacgatt acgtatcaat tccagatagg gagtggtcgc
    16741 tatacaaaaa gaattgaata aaacaggatt tgttttgttg gagtccctta cagcgcttat
    16801 gatcgcttct gtctgtgtct acttagtgag ctttggccag ctgtttttgc ttcaggcaga
    16861 aaagaaaagt ggggaggaac tgctatttat tcgaatgatt tatgaagata tcaagacgca
    16921 gcggatgtat cacaaaagac cagagcgaag ggaagaaatg atcccatacg atatccaaat
    16981 tgtcgataat aatggagtaa tcgaaaaagt gtttgtcaat atggagaaag aagcgatcag
    17041 tattgaaaaa acaagtaatt ccagcattta cgctgattga atgtctaatt ggactgatga
    17101 tattgagcag tctattgctc acattcaatc ttttgattca gcaaaccatc caagtaagtg
    17161 aatttttgca gcgtaaagat caaaaagagt ggctaatatt tttagcacaa ttagaagaag
    17221 aactcaagag cagtcacaat gtctctgtga aaaatcagca actgcactac acgatcgagg
    17281 ataaacagta tatcatcgaa agatatcagg caatgatacg taaaagaaga acttccggcg
    17341 gacatcaacc tatgttaaca agtatcactg agcttcaatt attggaaaaa gaacacacaa
    17401 tttcttttta tgtacacttt gaaaatggag aagatggata tgccatatgg acaaaaaacg
    17461 atcagtagaa aatgttataa gggctctatt ttattttctg tcttgctttt atttctttta
    17521 tgtacgtttt tattgatggc agcattagaa agctaccgtt tgtcaatgga tcttaatata
    17581 cgaatcaaaa attattatat agcaaaaata atgaagcaga tggctttatc ggaacagtct
    17641 acgcttgccg aaagttcgga aggagttttt tactacacaa ctggatctgt aacatatcag
    17701 tgggtacaac agtccctatt cttagaggtg gaagtctcac cgtttatctt tcggttcaca
    17761 gaagaagtaa aaaatgatac agatactagt acagaatgat ggaatgttcg tgaaaacgcc
    17821 ctcttttctg ttataacact gtttttaata aaaaaatgtt tgccgtttca caaataaaaa
    17881 acagtgaaaa cgattgaaat tttgtcaatt gttcgataga attaaacagg tgaaaaaatt
    17941 gttataatat atctagaaat gaggtgcacc atgttaccag aaaaaatgga acaagggttt
    18001 aatcaaaacc tggaagctat tcagctttta cagaatgcat tgggaacttc ctttttagaa
    18061 gcctatgtcg aaaatgcaga aaatttaata gatgattatc aagtacgtgt ggtggatgga
    18121 gtgccgacaa aagagacaac gcaacggatc acagctcttt atgaagagtt gaagaaactt
    18181 tctttcgagc cagaagaatg gcgcagactg tctcaattac ttttattgaa gggcagccag
    18241 acagaacatt tgcaggcgaa ccatcaactc actcctgata gtatcggttt tttatttgtt
    18301 tttcttattg aacaactata cacaaataaa aaagcaccgg ttaagattct ggatattgcg
    18361 gcaggaatgg gcaacttgtt attaacagtt cttttaaacc tatcgaatgc ggggtaccaa
    18421 acagaaggaa ttggtgtgga tattgatgat acattgttgg ctgtcgcagc ttctacaagt
    18481 gatttgacac aagcaaatgt tcaatacttt catcaagacg ggttgcagga attattaata
    18541 gatcctgtcg attttgcaat cagcgatttg ccaatcggtt attatccgaa tgacgaaaaa
    18601 gcaaaagagt ttttaacaag taccgaagaa ggccatagtt atgcacatca tttattgcta
    18661 gagcaatcaa tgaaatatgt gaagccggat ggttttggtt tgtttttgat gccgagtgga
    18721 tttttagaaa cggatcaaag tgaagaaatc aaaaaatggt ttaaagaaga aggttatctt
    18781 caaggaatga ttcaattgcc agatgaattg ttccgtaata aacaatcgca aaaaagtatt
    18841 ttgatcttac agaaaaaagg accacaagca caacaagtaa aagaagtctt gcttgtgaaa
    18901 cttgcttcat taaaagaacc agagaaggtg acggaatttt tcaacgagtt taaaaactgg
    18961 aaatcatctg ctctgtaatc attcaacgag aaggagagtc atatgtctaa aacaattgca
    19021 atcaatgctg ggagttcaag tttgaaatgg caattatatc aaatgccaga agaaaccgta
    19081 gttgcgaaag ggatcgtcga acgtatcggt ttacaagatt ctatttttac catcaagtac
    19141 ggcgataatc aaaaattcga acaaatcatg gatatcgaaa accacgaagt agcagtaaaa
    19201 atgctgttag atcagttgat tgaactgcaa attttaagct cttatgatga aatcaccgga
    19261 gtagggcacc gtgttgttca cggaggagaa acttatgggg attcagtagt gatcgatgag
    19321 aaagtaatgg accgcattgc tgaattagca gaatttgctc ctttgcataa tcctgcaaac
    19381 ttaatgggga tcaaagcgtt taaaaagatt ttacctgaca ttttgagtgt ggctgtattc
    19441 gatacatctt tccactcaac aatgccaaag caaaattatt tatatagctt accggtgtct
    19501 tattatgaag atttcaaagt aagaaaatat ggcttccatg gcacaagtca tcgttatgtg
    19561 tcggaacgtg cggcaaaatt attgaacaaa ccgatcgaag aactaaaaat catcacttgc
    19621 cacttaggaa atggtgtatc gatcacagca gtcgatggag gtaaatccat ggatacttct
    19681 atgggattca caccattagc tggggtgaca atgggtacac gttcaggtga tatcgatcca
    19741 gctgttctcc catatttaat ggaaaaatta gagattgata ttgatgaaat gataaatgtt
    19801 ttgaacaaga aatctggtct gctaggccta acaggattgt ctagtgatat gcgtgatctt
    19861 gaaaagaact atgaaaaaga acatattcgt ttagcttatg acattttcgt ggaccgcatc
    19921 cgaaaataca tcggcggtta tgtgacaatg atgaatggtg ttgatgcaat tgtctttact
    19981 gctggtatcg gcgagaatga cggacatgta cgtagtgaaa tcatcaaagg tatgtcttgg
    20041 tttggttgtg aaatcgatcc agcgttgaat gaattgcgtg gtgaagaagt agatatctct
    20101 acaaaagaat caaaagtaag agtattagtg atcccaacag atgaggaact aatgattgcc
    20161 cgtgatgtgg agcgtctgcg cggctaagcc aaagcattcg ttaggataaa agatgaaacg
    20221 catgcaagag ggaattcttg catgtgtttt ttttgcggag aagaccgcaa aatggtaatt
    20281 taacttcaat ttcccttctt ttttacagga tcttcttagg gaattttgct tggaaaagtg
    20341 gtcaaaaggg aaaagactgg cattttattt attgattttc aggaaaatcc caatatttta
    20401 ttttcattca tctttataag ggacattaca tatgtaaaaa gaaaaaacat ttttagatca
    20461 gcctcgtggg ctgtcgactt tattcttcgc tttatgttta gctagaaaac cgatccgaaa
    20521 cattcattga tcgaataata aaaacttgat tttccacctg tactttgcct gaatcgtgaa
    20581 agcacaggta tgaaaatcaa gttttttgtt gcgaaaaaac gtcctagtca atcagttggc
    20641 cgagcggctg gcggctgatc tgctcctgat caataacgag tgcttcttgg aagtgttgct
    20701 gcaaaaagta gcggtcatgg ctgactgcta ggagcgttcc ttgatagtct tgcagcattt
    20761 cttcaatttc ttctcgagca tagctgtcga ggtgattggt tggttcatcc aaaatcagga
    20821 cgttgatttt ttctaaaaag agtttcagca acgccaaacg gattttttca ccaccggata
    20881 aatctttgat ccgtttaccc acatcgcttt gataaaagcc acttttggct aattgccgtc
    20941 gagcgacttc ttcgtttcca gtcaatgtga tggcgtaagc cagcaaacgg ctatcgggat
    21001 cggcaaactg cagctgctgc ggcaaataac cgatttgcaa gctactacct aatttgatgg
    21061 tgccaccgta aggcttttcc tcaccgagta ataatttgag taaggttgat tttcctgcac
    21121 cattgtcgcc gatgatggct aaatgatctc cacgatagac tgcaaaactg ctgtctttga
    21181 atagtacttg atcagcgtac tgctggtgca agttttgaat gatgaaaact tctttgccag
    21241 attttccacc attagacaag ctttgcagcc gatttttcgg gggaggtggc ggtttgacga
    21301 gtgtcagttt cgccaggcgg cgttccagtt ctttggcttt tttgaagaag gactcattgt
    21361 ctccttcatg tgcccactga cgaaaacgac gaatcatgac tttcaaccgc tggacttctt
    21421 tttgctgcag ttcgtaattt tttgtcagct cagccaagcg agcttctttc aagactcgaa
    21481 aacggctgta gtttccggga tactcaatca atgcaccttc ttccagttcc catgtttttg
    21541 tggtgacttg atcgagaaat tgccgatcat gagaaacgac cagaaccgat ttttttgtat
    21601 tctgtaaata gttttccaac cagcgaatac tgttaagatc taaatgattg gtcggttcat
    21661 cgagtaaaag taaatcggca tcggctgcta aaattttggc taaagcgact ttaactcgtt
    21721 cgcctccgct aagttctgtt aaccgtgctt cctgacggtg tggaatccct aagccttgca
    21781 agatcgctgc aatccggtct tctaatacgt aaccgcctag ttcttcaaag cgatgctgca
    21841 gctcaccgta acgggccaga cacttctcta agtttgtatc tggttctgtc atcaatgctt
    21901 cgtagcgact catttgctgt ttgaggtcct gtatctcagc ggcagaatgg agcaagtagt
    21961 ggttgacggt cgcttcggaa actgtaagtt cttgttcgac cgtcccgatc tttaagcctt
    22021 ttttgcgact gataacaccg ctgtcgacac cttctctgcc ggtcaagatt tgtaaaaagg
    22081 ttgatttgcc agttccgttg ataccgacta aggcaatttt ttcaccagct tcaatttgac
    22141 aggataaatc ctcaaataat ggattcccgc cgattgtttt tttaatagaa attgcttgta
    22201 tgatcatgat ctctctcctt gagaccactc aaaaaggcca tggttatcca tggcctgtgt
    22261 tatttaaact cagattatca tgagaaaaat accttgagat ggccattgat tttacgtgaa
    22321 ttcaactgtt ttggacaaac ttgtcccgtc aacagcaact gtaaaaccaa ttgcatggct
    22381 aaatgcgata tggtatcgtt ggtaattttc attacttgtt attttagtca tgcgcatcat
    22441 agtattttcc ctccttcgtg tagttgtctt ttccagtgta cctgaaagtg tcagaaagtt
    22501 caactagcgc tgacatttac ttaatattta tcgatgtgta attctgtcag agagcttttt
    22561 ttatctgact gagggtaatg tctcgtggac cacatcattg tattctgagc taaaccagcg
    22621 ttcaggcgaa atcatatggt gtttgataaa aaactttgtc tacatgactt ccttttgcca
    22681 tttgcttaat accgttgcat taaacagctc ttctctttgg aaatctcacc aacatcgcgt
    22741 tcaggagtat cgttgtggtt gcaatggcaa gcggtagcct ttcatcaatt cttgaatgat
    22801 ttaccgaatg tagcacttgc cttctcgcgg tacccgaacc cgaaataaaa ttttagtttg
    22861 gcgataaaat cggtatccgc catcgatact tcatattttt tcgtatcaga ttcatcggaa
    22921 acttccacat tgacgaacca ataagctttg gcatgcttag gtcgttttaa accacaccag
    22981 ggcgactaat cgccctggtg ttcacttttt tttattttac ttgaactcat tgactgtttt
    23041 ccctttattt taaacattat aaagaccgat gagtgcttgc cgcgtctttt gtttttatca
    23101 cggttttttg tgcaaaaaaa cctgccgata gttggcaggt cgtctacgtg ttaagctttg
    23161 gtgtggtctt tagctggcaa ttggttttct aaatcagttc ggacaacaag cacatcgcaa
    23221 gctgcgtttc taataacata ttcagaaaca gaaccaataa ataaacgttc tacagcattc
    23281 aatcctgtgg ctcctaacat aatcaaatct acttgattat cttctgggat ttctctggca
    23341 ataatttgtt ttggtgagcc atattctacg acagaggtta cattattcaa gccagctttc
    23401 ttcgcattgc tttcataatc tgccaatgtt tgctttgcca tttcagtagc ttgttctgca
    23461 agcattccat caaaggatga aacggtttgg aaagaacgtg tgtcaatgac atgtgctaat
    23521 agaagttctc cgttatttcg gatagctaca ttgaccgcct ttttaaaagc taattcagct
    23581 tcatcagaac catctacggc aaccatgatt tttttgtatt gttgtaacat aagcattcac
    23641 tcctcaagtc aatcgtattg tactctttta ttgtagaaca ctttagggaa aaagagaatt
    23701 atttactgct ttggttcagc aatttttttt gcaaatcgga tactgaaggt ggcagaaaca
    23761 ataattacga tcagtaaaaa gaccaaggca ataaagcgtt gattgaaaaa agctgttaaa
    23821 atacccatta cgcctaaaac agcatatgca gctccgtaaa attgtaggaa tccttgattt
    23881 ttatcatttt tgttgatcaa tacaaaaaag atatcctgtt tattaaataa ataatagcta
    23941 acgaataata atactaaagt ggcgataatc attaaaatcc taatcatgaa caaatcctcc
    24001 aaaataagca acaaatagaa aaagcaattt gccaagagca aattgcttta ttctttaaaa
    24061 gatggtaatc tccgttaatg ccgttgtttg tcctgtagta ttgatcccgc gaattcaagc
    24121 aggtgggtcc catggtcgta gcttcgaact accaaatgat aaggcatgtt accagcagtg
    24181 acacaagacg ggtcccaaga tatcaataaa aatgttcggt caacacacaa agaggacaat
    24241 tcgaacatca cagatttccc acctctatag tagcatatga atttaaaaag agcaatgaga
    24301 gagctcgcag aaacagaacc gttttcttgt ctagtttttt ggaggatgct ttttccactc
    24361 ttttatacgg taatactgtt gacccagagc ctgttcatat ttccctgtat cttttggctg
    24421 ataatactga gcactcttca gtttatctgg taaatattgc tgattgaccc aagcctgatc
    24481 aaaatgatga ggatactgat aacccacgcc acggttgagt gatttcgcac ctttgtaatg
    24541 gctatctctc aaatgatcag gaacatctcc agctttgccc tctcgaatat cagcaagtgc
    24601 tgcatctaat gccatgtagg cagaattgga ttttggcgac aagcaaagat cgacgacgac
    24661 gtctgctagt gggatacgtg cctcaggcaa tcccaatttt tcagcagcta atacagcgtt
    24721 cactgtacga gccgcagcag caggattacc taaacctata tcttcataac cgataaccat
    24781 cagacgccgg caaatacttg ccagatcacc tgcctcaact aaacgggcga gataatgaag
    24841 tgcagcatcc acatcacttc cacgaatcga tttttgaaaa gccgaaataa cgtcataatg
    24901 agcatctcca tttttgtcat gggtaagagc ttttctttgg acacattctt caatgatcga
    24961 cagtgtaaga tgaatccttc cttctttatc tgaaggagtc gatagtgtag ccagttccag
    25021 cccattcaat gcactccgca aatcgccgtt cgttgcacgc gaaaggtgaa gaagagcatc
    25081 ttcgtctaac tggattgctt gttgtccaag gccgcgttct ttatccctta aagcatgttc
    25141 gactgccaac tggatgtctt gttctgttaa tggtttgact tcaaagatct gtgtacggct
    25201 gcggatcgct ggattgatgg taatataagg attctcagta gtcgctccga tcaagatgat
    25261 tcggccactt tctaaatgag gaagcagaaa atcctgtttt gttttatcta atcggtgtac
    25321 ttcatccaat aagaggatca ctgtaccact catttttgct tcttccgcta caacttgtag
    25381 atcctttttt gaatctgtag cggcgtttag catgcgaaat gcataattag tagagccggc
    25441 gatcgcactt gcgatactcg tttttccagt accaggaggt ccatatagaa tcatggaaga
    25501 gagcatgcga gcatcgacca tgcggcgtat gatttttcct tccccgacta gatgctgctg
    25561 accaacgact tcatcgatcg ttcgaggtct catgcgataa gccaatggct gttgcatagg
    25621 attttcctcc ttcttgtttt tacgtccctt aattatatca tatttagcaa gatgcctaga
    25681 aagaacagcc ttctgttgtt ttgttttcat agcttatcca actaatattg tgtatgataa
    25741 agtaggtgag aaaaatgacg gataaacaaa agatagatga atttttttgg aataaaacga
    25801 cgccagaagt ggcacgggat ttattgggga tgtatttgga gcatgacaca ccagaaggaa
    25861 gattagctgg atatattgta gacgcggaag catacctagg tccagaagac gaggccgccc
    25921 atagctatgg tttaagaaga acaccgcgtg tgcgggcaat gtatgaaaaa ccaggtacga
    25981 tctaccttta cacgatgcat actcatcgga ttttgaacat cattactcag ccagaaggga
    26041 ttcctcaagg agtaatgata cgtgcaatcg aacccgccgc aatgattgat caaatgagta
    26101 aaaatcgtgg cggaaaaact ggtccagata tcagcaacgg tccgggaaaa ttagtggaag
    26161 cattagcaat tcctcaagaa ctttatggtc agtctatagc agatagttcg ttacgcttag
    26221 tttttgagaa aaaaaagaca ccaaaaaaga tcaatgcttt gcctagaatc ggtatcccaa
    26281 acaaaggtgt atggacagaa aagccgttgc gttttgttgt gtcgggaaat ccttatatct
    26341 ctttacaaag aaaaaaccaa atcgagaaag attggggttg gaggaaagaa aatgaaaaag
    26401 aaggatctat taacatattt agatgaaata attgaaaaac aagtgacaga ctatgatgta
    26461 gctttagatt gggatacaaa aaatcatacg atcgagatcg ttgttcgctt gtttgcagaa
    26521 aataaagcac aatttgagat tgatgatgca gaagggatcg tttcgcaaga accaattatc
    26581 gaatttgaag acggcgtact tctttttaat cctcagaaat ctgtttttga tgaacgcaat
    26641 tatctagcag taatccctta tgaaggaaaa aaagggttgg caaaatcagt agctgattct
    26701 ttagtggaat atctaaatga agtattagct caagggcaaa gcgatttgct tgattttttg
    26761 gatgaagacg atgacgaagc tgtattcgag cttcactggg ataatcagca actagcagaa
    26821 ttagtagaag taaaacagca aaatgaagca gatacttatt taccgtaccc aagttattaa
    26881 ggagtgacag atatgaaatg gaatgaagta aaagtagaaa ctgaaagtga agcagtcgaa
    26941 gcagttgcta atattttgat ggaggcaggg gcgagtggtg tcgcgattga agattcttta
    27001 gatgttgaac attttcagtc ggatcaatat ggtgagattt tagataaaaa tgattttaca
    27061 tcgctgaaag aaggcgcact agtcatggct tattttccgg aaacgacttt cttaccggaa
    27121 atcttgcctt ttatcaaaga tcgtatcaca caattacctg agtttggtct agctattgga
    27181 aaaaataaag taacagttag tgaagtagag gaaagcaact gggcaacagc ctggaagaaa
    27241 tactatcatc cggtgcgtat tacgcgaatg ctgacggttg cgccaagctg ggaaaactac
    27301 cagacagaag atcctctaga aaaaattatc acactagatc ctggtatggc atttggcaca
    27361 ggcactcatc ccacgacttc cttgacattg acagcactag aaacagtctt gcgtggtggt
    27421 gaaacattgc tagatgtggg aactgggtcg ggcgtgctaa gtattgcagc aaaatatctt
    27481 ggtgcaaaag atgtctatgc ctttgattta gacgaagtag ccgttcgttc ggcgaaagaa
    27541 aatatggata tgaatgaaat agccaaagat gtccatgtat cagctaacga tcttttgaca
    27601 ggaatcgaga ttgaaagtga tgtaatcgtt gcgaacattt tagcagatat catcttattg
    27661 atgatcccag atgcttggcg tttactgaag caaacaggca cgctgatcgt ttcaggaatc
    27721 attgaagaga agaagcaaat ggttctggat gccatgttag aacaagggtt tatcgtggat
    27781 caaattttcc agcaaaaaga ctggtatgca attattttga aaaaaccaga ggtggaatag
    27841 atgcagcggt attttttaaa agaatcatat gaatcaaaag actattttgt tttagaaggg
    27901 gaaaactatc accacattgt acgggttatg aggatggaac ccgaggatga agtttttttg
    27961 gcattcaatg atcaaatagc cattgttgca gaaatcacgg agattactga agaggctgtt
    28021 tatctgaaag aaattaaaaa agaagaaaat caaaaggaac tgccaagttc gattaccata
    28081 gcgagtggct atcctaaagg ggaaaagctg gattggatcg ttcagaaatc cactgaatta
    28141 ggagcgcaag cttttcttgg tttcccggca tcagcctctg tcgttaaatg ggatgcaaaa
    28201 aaacgtatga aacgacaaca acggcttgaa aagattgctc aagaggcagc ggaacaatcc
    28261 catcggcaga tcgtgccatc agtagagtta ttggaaacga aacaagattt atttgagcgg
    28321 ctagatgatt atgacgtggt cttggttgct tatgaggaat cagcaaagca aggcgaaaaa
    28381 tcaaatgcag ccaaaattct tagtgaaaca aaaccagata gtcgaatctt agctgtcttt
    28441 ggaccagaag gtggattatc ccgcgatgaa gtcgattatt ttgtagaaca caaagggata
    28501 ctttgtggat taggaccaag aatccttcgt acagaaacag cacctcttta tttattaagt
    28561 gctgctagct atcaatggga attaatgaat ccttctttca gctaacgttc ttcattaata
    28621 aaagagtatc gacagaaaga attgaaaaaa tagtcaacaa tttgtataat agaaacaatt
    28681 atttatacaa tggatacgaa aaatcgtttg aaaaagcttt taaaaagcga acatttccgt
    28741 aaaaaaacgt ataactgcac ggattttggg acaattatca aacagatatt tgtcccgatt
    28801 cccgttttac cgaaaaaaga aagggggatc gattcctgtg acaaaagaag aaattttaac
    28861 gggacccggt gtcataaagc tcgttagtca atacatgggt cccgaacatg tagcatttgt
    28921 tgagaaagca tgcgaatacg cgactgctgc acatgacgga cagtttagaa aatcaggcga
    28981 accctacatt attcatccta tccaagtcgc aggtatatta gcagatttaa aaatggatcc
    29041 ccatacagtg gctacaggct tcttacatga tgttgttgaa gatacagaaa tcactttaga
    29101 agatctgaga gaagaatttg gcgatgacgt tgctatgtta gtggacggcg taaccaaatt
    29161 agggaaaata aaatataaat cccacgaaga gcagctagca gaaaaccacc gaaagatgct
    29221 gctagcaatg gctcaagatt tacgagttat catggtcaaa ttagctgata gactacataa
    29281 catgcgtacg ttgaagcacc tgcgagaaga taagcaaaga aggatcgctc aggaaacttt
    29341 agaaatctat gcgcctcttg cacatcgtct agggatcagc cggatcaaat gggaattaga
    29401 agatacagca cttcgttatc taaatccaaa acagtattac cgtatcgtcc acttgatgca
    29461 gacgaagaga gaagaacgtg aaaaatacgt aagtggtact gttgaagata ttcgaatagc
    29521 gacagaagag ctggggattt ttgcagaaat ctatggacgg ccaaaacaca tttattcaat
    29581 ctatcgtaaa atgaaagatc agaaaaagca gttcaacgaa atttatgact tgctagctat
    29641 tcgagtgatc gtagattcaa tcaaggattg ttatgctgta ttaggagcaa tccacacaaa
    29701 atggaaacca atgcccggca gatttaagga ttatattgcc atgccaaaag ctaatatgta
    29761 ccaatctttg catactaccg tgatcggtcc ggcaggaaat ccggtagaaa ttcaaatccg
    29821 aacacaggaa atgcatgaaa tcgctgaatt cggggttgct gcacactggg cctataaaga
    29881 aggaaaaaat gaaaaagtag aaccagatgg tatgacgaaa caattaagct ggttccatga
    29941 gatactcgaa cttcaagacg aaagctatga tgcttctgaa tttatggaag gcgtaaaagg
    30001 agatatcttt agtgataaag tctacgtctt cacaccaaaa ggagacgtta ctgagttacc
    30061 aaaaggatcc ggaccattgg actttgcata cagtatccat acagatatcg gtaacaaaac
    30121 cactggtgca aaagtaaatg gcaaaatggt gcagcttgat tacaaattga aaaacggaga
    30181 tatcattgag atcatgactt ctccaaattc atttggccca agtcgcgact ggttgaaatt
    30241 agttgctact agcaaagcaa gaaataagat caaacgtttc ttcaaagccc aagatcgaga
    30301 agaaaatgtg atcaaaggcc acgaatccgt ggtcaaatgt attacagatc taggatttac
    30361 gcctaaagat attttgacga agaacaaact gcaagaagca ctcgatcgtt ttaattatca
    30421 aacagaagat gatctctatg cagctgtagg gtatggagaa gttagcccct tgacgatggc
    30481 caatcgtctg actgaaaaag aacgtaaaga acaaaaaatc gagcagcaaa agcaagaagc
    30541 agaagaaatc atgaatcagc cgaaaaaaga acctgacaaa atgaaagtac gtcatgaagg
    30601 tggcgttgtc attcaagggg tagaaaactt actaattcgt atcagtcgct gctgtaatcc
    30661 gattcctggt gatgatatcg ttggttatat cactaaaggc agagggatat ccattcatcg
    30721 tcgagattgt ccgaatgttc agcctgacaa accaaatgta gcagaacgtt tgattgaagt
    30781 cgaatgggaa gatacatcga atacacgaaa agagtatgat gcagatttgg aaatttacgg
    30841 ctataatcgt tcaggcttat tgaatgatgt acttcaaaca gtcaatgcgc taacgaaaaa
    30901 tctcaacagc gttgaagcac ggacgaataa agataaaatg gcgacgatcc atttgacggt
    30961 tggtatccag aatttatccc acctaaagag tatcgtggat aaaatcaaag cagtacctga
    31021 tgtctacagt gtacgccgga cgaatggata ggaggacaga tatgagagca gttgttcaac
    31081 gggtaagtaa agctgctgtg tcagtcgatc agcaagaaat tggaaaaatt ggctacggcc
    31141 tacttgtttt attaggcatt catgaaaccg atacgcaaaa agatgtggac tatctggtaa
    31201 aaaaaattgc acaaatgcgt atttttgaag atgaacaagg aaaaatgaat attagtgtag
    31261 aagatgtggg aggacaaatt ttaagtatct ctcaattcac actgtttgcg gatacgaaaa
    31321 aaggaaatcg accaagcttt gtggaagccg cacgaccaga aacagctatt cctttatacg
    31381 aatcattcaa tgaaggaatc agaagtcgcg gcatcacagt cgctaccgga caattcggag
    31441 cagatatgtc ggtttctctc gtcaatgatg gacctgtaac gatcattatt gattctaaaa
    31501 acaaataaag taatctggtt ttcactagta aaaactatga aacacgtcgc ttaagttaga
    31561 ctgataaact ctaacttaag tggctttttt gtctgcaaaa agcgcttctt ttgtcagcag
    31621 tcggaaaaaa agttaagctt aaattataca agttattttt tataggaggt tgctgaagat
    31681 gaaagaagta ccagtagtag atatcaaaat cacagattta aaaaaattgt atcaaaaagg
    31741 atacaacatg ttggaggagt tacgccatga agcggacgct cccgtcgtca aagcaaagat
    31801 tttcaataaa gaagctatca cgatctacgg atcatcagca gcaaaagtat tttatgatcc
    31861 aaggaatttc aaacgaaaag gtgctatgcc aaaattagta ttgaagacac tttttggtca
    31921 aggtggagta cagactttgg atggagctgc tcatcaccat cggaaaaata tttttatgga
    31981 tctaatgaca ccggaaagaa tggaagatta tcatcgtatc ttagataaga atctgacaca
    32041 agcacttgaa gcacagcatg gtcaatttga actatttgat ttaagtaaga tggttttctt
    32101 tacatctatt tgcgagtggg caggtatcaa tttatcagcg atttctaaag atgaggtcga
    32161 aaaattagca gaatatcaaa tctctatgat cagcggaacg tttacttctc cgattgatca
    32221 cataaaaggt gtcgaaaatc gcaaaaaatc agaaaaatgg gcgcaaggct tgattgaaga
    32281 agctcgacaa aatcctgtgg ctggaaaaga aaatgtggca ttatatgctt ttgccaatgc
    32341 cacagattta gatggtcagc ttttacctct ggaagtggca gctgttgaat tattgaacat
    32401 catccgtcca acggttgctc taactgtgtg ggcggcattg atgggacatg cacttttcag
    32461 tagaccagat ttgtatcagc aattaaaaaa tgacttttcg acgttacaag atccgtttat
    32521 tcaagaaatg agacgctatt atcctttctt cccaatgcta cctgcgattt cgctgaaaga
    32581 agtagaagta gatggttatc gtataccaga aggcagttgg gttattttag atttatatgg
    32641 aacagaccat gatgaacgaa cagttgaagc gccagattcc tttatgatca aacggtatgt
    32701 agggaaagca aaagatattt cctataaaga agaatatgag atgattgcac aaggcggggg
    32761 aaattttcga caaatgcatc gctgtgcagg agaatggatc actcttcata gtctacgtgt
    32821 gttttccgat cagctagtaa ataagtttga gttctctgta cctgaacaag attggacgat
    32881 tccattcaat cagtttccga cttatccgaa tagccgagcg ctactttaca agaattagat
    32941 tagcataaac ttatcgaaaa aaaggaagat caaacagtgc tgatcttcct tttttcatat
    33001 tactataaat tgataaggtc aattgatcaa aatccacgaa atgcttcatc aatggtttga
    33061 taatcttcat tggataaatg caaatctaaa gcttggacat tgtcagatac ttgctctgga
    33121 cgcttagctc caggtataac tacagacact cgtggattct tcatgtacca agctaaaaca
    33181 agttgcgcag gagtggcttg gtatctttta gcaatggggc gaagtacatc gacagcggtt
    33241 aaaatttctc tgaaacgttc tccttggaaa tctggatttc tttttcgagg atctccttca
    33301 ccaaattgtt tttcctcacc aagttcatat tttcctgtca gcaaaccgga agcaagagga
    33361 aaatagggaa caaaactgat tttgtttttt tcaagataag ggaataattc tttttcagcc
    33421 tgccgatgga tcaaactgta tttatcttct actacatcga catatccatc tgcattcgct
    33481 tctttcaatt gttctaacgt gaagtttgac acaccgactg ctcggatttt tcctgcttct
    33541 tttaattcgt gcaatgtagc aactgattca ttttttggtg tgctttcatc cggaaagtgg
    33601 atataaaaaa tgtcgatgta atcagtttgc agacgtttta gtgcatcttc caccgattgt
    33661 ttgagaaact caggagaatt atcaaatgtt cgccctttat ttggtacatg agcagctttt
    33721 gtagcgatga cgacacgtga gcgatcatat tctttttcct tcagtacctc gccaatcagt
    33781 tcttcggaac ggccgtttcc gtaagcataa gcggtatcga tcaaattgat cccgctattc
    33841 aaagctgtac gaactacttg ttttcctgtc tcatcttcca aaccgtcaaa aagattatgt
    33901 cctccaacgg catttgctcc taatccaagc tgttctgcgt agacttgtga atgtccgatt
    33961 cttatttctg ccatagctga ttcctccttt ttgtctagtc taaaacaaaa taccaaaaag
    34021 ctgaactaaa acgtttttgt gaggggaaat agtcagatat ctcttgactt tgagactggt
    34081 ttttagtagg ttataagtaa tatcgaatgt caatgaaaga gcgagtaagt ttttgaaact
    34141 ttacaagaga ggatcatcga ggctgaaaat gatctaaagt ttcattagcc taaagacact
    34201 ctggagatgg acgagtgaaa agccgtcccg cgtacgagcg ttattcgtaa gaggaaagag
    34261 aaatctttca aaattaggtg gtaccgtgta tgaatttcat tcacccttgt tcatgatgaa
    34321 caagggtgat ttttttattt acatagctaa gaaagggaga gaaaactatg agtttccaaa
    34381 gaccaaaagg aacaaatgat attttgccag gcgaatcaga aaaatggcag tttgtcgaag
    34441 aaacagcacg tttattattc agagattatc agtataatga aatgcgtaca ccgatttttg
    34501 aacactatga agtgatatcc cgaagtgtag gggatacaac ggatatcgtt tcaaaagaga
    34561 tgtatgattt ttatgacaaa ggggaacgcc atgtgacgct tcgaccagaa ggtacagcac
    34621 caatcgttcg ttcttttgtt gagcataaat tgttcggccc agagtatgcg aaaccgttca
    34681 aaacttttta tatgggacca atgtttcgct acgaacgccc tcaaaaagga cggttacgtc
    34741 aattccatca aatcggagta gaagcatttg gatcagaaaa ccctgcaact gatgtggaga
    34801 gcatggtgat ggcacttgat ttcttcaaac agttggggat cacgcaaatc cggctagtca
    34861 tcaattcatt aggtgataaa gaaacgcgtc aagcctatcg tcaagcattg atcgactatc
    34921 ttttaccttt tgaatcagag ctgagtgaag actctaaacg ccgccttcat gaaaatccat
    34981 tacgcgtatt ggacagtaaa gacaaacgag atcaaaaatt tgtggcagaa gctccatcta
    35041 tcttagatta tctaagcgag cctgctcaaa aacattttga taccgttgtt tccatgctgg
    35101 atgcattggc tgttccttat gaaatcgaca gtaatatggt tcgcggacta gattattaca
    35161 cacatacgat ttttgaaatc atgagtgacg caccaaaaat gggggcacaa gcaacgattt
    35221 gcgcaggcgg acgttatgac aatctagtgg aagaactagg tggtccttca acacctggct
    35281 tcggatttgc aatgggtatc gagcgattac tcttgactat ggaggcagag gaagtagtta
    35341 tccctgcatt taatgagttg gatgcttacg tggtcgcact cggagacgaa acaaatatcg
    35401 aagcattgaa agtggtccaa gcgattcgaa actttggttt ttcagctgac cgcgacttca
    35461 tgaaccgtaa agcaaaagcg caatttaaga cagcagataa agcgaatgcc aaattagtat
    35521 tggtgatcgg tgaagatgag cttgctagtc aaacgattaa tgtcaaagca atggcaagcc
    35581 gaaaagaaaa aagttttcca ttagaagaga tatatgaaca ttttgatgaa gtctatgatg
    35641 aaatgacttt attcgagtag gaggaaaaaa ataaatggca caaagaacga tctattgcgg
    35701 attagtttcc gaacaacaat tagaacaaac agttacatta aaaggatggg tacaaaaaag
    35761 acgagacctt gggggagtaa tctttatcga cctacgtgat cgtgaaggaa tcgttcaaat
    35821 cgtctttaat cctgaaatca acaaagaagc atgggaaatc gcggataaat gtcgcagtga
    35881 atacgtgatc gaagtgactg gggaagttag aagacgcgga gaaaatgcag taaatcctaa
    35941 aatggccact ggtgaattcg aagtgattgc aagtgaaatc gtgattttga atcaagcaaa
    36001 aaccccgcca tttcaaattg aagatgatca agcaatcagt gacgaaatac gtttgaaata
    36061 tcgttatttg gatctgcgtc gtccaaaaat gactaaaaac atcaaattaa gaaatgcgac
    36121 aacaaaagcg attcgtcatt atttagatga taatgacttt ctcgatatcg aaacacctta
    36181 cctagggaaa tctacaccag aaggcgcaag agactaccta gttccttcac gtgtccatgc
    36241 tggacatttc tatgcgttgc cgcaatctcc tcaattgttt aaacaattgc tgatgaatgc
    36301 tggattcgac cgttattatc aaatcgttcg ttgtttccgc gatgaagatt tacgtggaga
    36361 ccgtcagcct gaatttacgc aagtagatat tgaaacaacg ttcttaacag cagaagaaat
    36421 ccaaacttac acagagggat tgattgcgaa ggtaatgaaa gaagttcgcg gtatcgaagt
    36481 cacattgcca tttcctcgta tgacctatga tgaagcaatg gctcgctacg gcagcgacaa
    36541 accggataca cgttttgata tggaattgat cgatctaagc gatacagtca aagaagtaga
    36601 attcaaagtc ttccaaatgg ctcttgaaaa cggcggtgtc gtgaaagcat tgaatgctaa
    36661 aggcgctgca gatcgctact cacgaaaaga catggatcag ttaggtcaat atgtaggaca
    36721 attcggagct aaggggcttg catggctgaa agtagaagaa gacggattga aaggtccaat
    36781 tgctaaattc atgggagaag caacagaagc aatcattaaa gcaacagatg caaaaccagg
    36841 tgacttgctg atgtttggcg cagataaaag tgaaatcgtc gctgctgcat taggtgctat
    36901 ccggacacgt ttaggaaaag aattaggact aattgatgaa tcgaaattca atttcttatg
    36961 ggtaactgat tggccacaat ttgaattttc agaagaagaa ggtcgatatg tctctgctca
    37021 ccatccattc acgatgccaa aagaagaaga tatcccgtta ttggctgaag accctgcaaa
    37081 agtctatgca gaagcttatg atatcgtctt gaacggttat gaactaggcg gaggttctat
    37141 ccgtattcat actcgtgagc ttcaagaaaa agtactagaa actctaggct ttacaaaaga
    37201 acaaatggaa gaacaatttg gtttcttgtt aacagcttta gattacggat tccctccaca
    37261 tggcggtatt gcattaggat tggaccgttt tgcaatgtta ttagccggag aagataatat
    37321 tcgtgaagtc attgcctttc ctaaaaacgg aaaagcagca gatgtgatga gtgatgcacc
    37381 aagtatggtt tcgcctttac aattgttcga attgaatatt gatgtaacga atatagaaga
    37441 atagccgata aaaaggtaaa aaggatttgt cgaatacgct tcttttgaca accttgattt
    37501 aattgaaaaa cactttataa tgaagccata acatataaag cggggctttt ccatgaaaaa
    37561 aacattcgaa aattgggctt atcatgatta cacgaccaag ctttcggtat ctatcgttta
    37621 tgcgttgatc gcatcagtcg cattgaattt cttttatcag ccaggacata tttattcaag
    37681 tggtattact ggtctagctc agattttgac gactttgtca aaatcactga taggattcga
    37741 agtaccggta tcaacaactt tgtatttact gaatatacct ttgtttgtat tggcgtggtt
    37801 aaaaatcggg aagaagttta caattttcac ttttatcaca gtcactttga cctccctttg
    37861 tatccatatt ttaccggaaa cagtcctatc taccgatcca atcatctgtg cgttgtttgg
    37921 gggggctgtg atgggactag gtattgggct agcgttgaga aacggcctat catcgggcgg
    37981 tctagatatc gtgagtatca cgattcgtaa aaaaacagga aagtcgattg gttctatttc
    38041 gatctacttc aatgcattga tcgtttttgt tgccggaatt ctatttggct ggcaatatat
    38101 gttttacagt acgttgtcta ttttcgtcag tggaaaagta actgatgtcg tttatactaa
    38161 acaaaagaag atgcaggtaa tgatcgtaac gaaacatcca gaaaaagtag taaatgaaat
    38221 ccaaaactgt atgcgtagag ggatcacgat catcaatgaa gcagaaggtg cttataagca
    38281 tgataagcag acagtattga tgacgatcgt tacacgatac gaactgcctc tacttagaga
    38341 agcaatgaaa gcttctgatc cacaagcttt tgtaagtatt gcagaaaacg tccagatact
    38401 tggtcgtttc tatgaggatg gcatttagat cgagtttgac aaaaattcat gaaatactgc
    38461 tgtagacaga cgttcgtttg tctgcagttt ttttctacca tagtagaatc agcaaagaaa
    38521 aactgctttt ttatttgaaa ttttcttaaa gttgaaaaaa agcatgttta tttttttaaa
    38581 tttatgggat gatagaaaaa aatagtagag aaaggacacg attctacttg ctattttcac
    38641 ttaatacccg tatattacga atgaaaaaag tttatgaaaa gttggaatat tgaatggaaa
    38701 aacaaaaaag gttaaaaaac agccgctaca tcactgggtt tgatgggctc cgttcattag
    38761 ctgtggtggg tgttatcttc tatcaccttc tgccaactag tatgaaaggc ggctatttgg
    38821 gcgttccgat ttttttcgtc gtatctggtt atttgatcac ggatctgctg cggcaggaat
    38881 gggaacaaaa tggaaaaatc aatatttggc aattttatgt cagaagaatg aagagactct
    38941 atccggcact tgtttttatg cttgtgacag cttcggctta tatcactttg tttcagcgag
    39001 ggctgttaaa caatcttcga ggagttgtgg tcagcagctt actgtatgtc aacaactggt
    39061 ggcaaatcaa taacggttta tcttatttcg atcgatttgc taatgagtca ccgtttacgc
    39121 atatctggtc tttagcagta gaaggtcaaa actatttggt ttggccgatc ttgtttgtat
    39181 tgttgatggt atttgttcgt aaaagaaaat ggatctttta tactgtgtta ggtacatcct
    39241 tcctctccgc catcttgatg atgatcttgt atacaccagg aggcgatcca acccgtgttt
    39301 attacggtac cgacactcgt ctgttttcta tatggttggg aagtgcgctt gcgtttgttt
    39361 ggccaagtac gcgtttaaag aaaaacatcc cgaaacaagc gaaaaatatt ctgaatatcg
    39421 ctggaggaat ctcgcttttg gcactgattc tttgcttctt ctttttagat gatcattaca
    39481 atttcatcta ttacggagga atgctcctag tgagtctgtt atgcgtagtg ctagttgcag
    39541 tgacagcaca ccccggagca agtttgaatc gatggctgac aaatccagta tttacttgga
    39601 ttggcaaacg aagctatggc atttatctgt atcagtttcc agttatgatt ttttatgaag
    39661 caaaggtgac tgatattgcc gatcatgttt tgttgcatac tttagtggaa atcacattga
    39721 ttctaatcat cagtgaactt tcttatcgat atgtggagcg tccgctagca cgttttgatt
    39781 atggtcgtac attccaagtg atgaaaggat ggttcagcaa accgatcatc agtaagagca
    39841 aaccatgggt tgttccaggc acattacttg tagcaattgc actcgttggt ttcgttacgg
    39901 caccgaaaaa cgctgtaaca gccgatcaaa aacaactgca ggcaaaaatc gctgaaagta
    39961 aaaaattagc agaagaaacc agaaacaatt cagaaaacac cactagttcg gttgaccaag
    40021 cgatccttga taagtacgag ttgtccaagg cacaagggaa taaggcacaa aaattagaac
    40081 taacggcatt tggtgattca gttatgttgg atgctgcaac ggatctacaa gaactttatc
    40141 caaaagtagt ggtagatgga gatgtcggac gacaattata tgccagtgta ccgtacattg
    40201 aaaaattaaa ggaacaagat ttgttgaaag acactgttct gatcggacta ggaacgaatg
    40261 gctcattctc ggaagctcag tttgatagtg tgatggatgc aatcggtgat cgaaaagtat
    40321 actgggtcaa tgtccgagta ccgacgaagc gctggcaaaa tgacgtgaat gcgatgcttg
    40381 aacagatgac gaaaaaatac gacaatatga cgctgattga ttggtacagc tacagtaatg
    40441 accatagtga ctggttttat gatgatcaag tccatccaaa tcctgaaggg atgacacatt
    40501 acattcactt agtcagcgaa gccttgctag gaggaagttc aagtacgaac agcagtgaga
    40561 caaacgtgac agaatgatag ctacaaaaaa cttcaggcaa aaacatttgt ttttgcctga
    40621 agttttttta tatttaccgt gtttttaaca ttcatataga ttcaggaagc aaaacggttg
    40681 agtgtgtctg taaataacgt tctttttgtt ttcgggtgag ttttttgaat gcagcttctg
    40741 cttttgttgc ttcgcttctt gaagaaaata cttctgcatg gatcatctta acaggtcttc
    40801 ttttttgaag acgagtatat ttagcaccag taccattgtt atgttcctct aatcgtctag
    40861 aaagatcggt tgtatatcca ccataaaatg tctgatcttt acagaataat acgtaaaaat
    40921 aatgttcatt tgccatagag catctcacga atctctgcag tgtattctcc atccatattg
    40981 taagtgatca atggtggagc gactttgaat ccgtctaatt tgccttcttt gattccttca
    41041 actaacaaaa tatttgcctc ttttccaggt tttgggtaaa caaattggat ccttttaggt
    41101 gcaattcgat agtcttccat gacctgaatg atttctaaga accgatcagg acgatggacc
    41161 atagtaaagc gtccatttgt ttttagtagc ttacttgaaa tatcgatcac ttcttctaac
    41221 gtcgtatgaa tctcatgacg ggcgattgcc aggtgtttat tagggttcgt tttatttgtt
    41281 ggcagccctt tgaaataagg tggattacag acgactaagt cacaagaatt atgtcgaacg
    41341 acagataagc tgtctttcag atcgatggtg tggacagtca tttgttcatt taaatggtta
    41401 agcgcgatac tacgtcttgc catgtctgct agacgaggtt gaagttcgat agcgtcgata
    41461 gccgcctggg ttcgtttact taaaaaaagt ccaactgcgc catttcctgc acaaaggtca
    41521 acaatcttcc cttttttagg tacacgggaa aagtgagcaa gcagcacagc atctaaagaa
    41581 aaagaaaaca ctttggaact ttggataatc ttgatatctt ctgcgtataa ttggtcgatt
    41641 cgttcgtctt cgtgaagcat ggattccctc caaaatgaaa aaaatagtcg tctgtattat
    41701 actattttta ttaaaaagaa ccaaggtggc ttgtcaaacc tctatttttt atgcatacta
    41761 tgaccataag aagggaaagg aagagactat gttttatcga tttatgcgcg gggtagttcg
    41821 agtactatta gccttagtta atggaaatgc ccgctatgag aataaagaag ttttaccgca
    41881 agatgagaat tacatactag ttgctcccca tcgtacttgg tgggacccat tatatctggc
    41941 ggtagctgca gcacccaagg aattcagctt tatggcaaaa gaagaactgt tcaaaaatcc
    42001 agttctgcga tttatattaa ctcgatccaa tgcttttcca gttaaaagag aaaatccagg
    42061 accaagcgtc attaaaacac ctgtaaagat tttgaaatcg acaaatttga gtttgatcat
    42121 gtttcccagt gggacaagac atgctacaga acttaaaggc ggaatggcat tgatttccag
    42181 aatgtctaaa gcgaaaatcg tgccagctgt atatcaaggt ccgttgacac ttggggatct
    42241 gttcaagcgt cagagagtga cagtgcgttt cggcgaacca atcgacttat cagatatcaa
    42301 gaaaacggat aaagaaggta tggcggagat cgaacgacga acacaagcag cttttgacaa
    42361 attggacaaa gaagtgaacc ctgatttcaa atatgaagtc aaaaaaaaat aaaatgataa
    42421 gtttatgcgt gggcggtctt ttgaatctac tgtcctgttc agttcagact ttttcaatga
    42481 aaacgaggga gagacgtcaa gtctgccctc tttttgcgtt ccaatatgta aaatagaaga
    42541 caggtgtcat gtaatggatc aaagtgttat aataattaga aggacatttt ttgaggtgat
    42601 tgaatgcgtt ttttacatac agccgattgg catatcggaa aaaaactaca aggttatgac
    42661 ttgattgaag accagcgtca tgtactatct tctatactag atatcgcgaa agaagaaaaa
    42721 gtagaggcaa tcgtgattgc cggagactta tatgatagga gtgtcccagc tgttgatgcc
    42781 gtagaattat acaatgaatt gatggtcgat tggaatttaa aggaaaagat cccgattttt
    42841 gctatatcag gaaatcacga tagcagtacg agactttcag cgggtacgcc atggttcagt
    42901 tattcgaact attttttgcg aacacagcta gcagaagcat ttgaaccagt cgagtttaaa
    42961 aacgtacaat ttttctttct tccttacttt gaaccaattg cagcgagatt atattttgaa
    43021 gatgacaata tccgaacgat caagcaagcg gtagccaagg tgatagataa aatgcaggag
    43081 ctatttgatt cagaaaaaaa acaagtattg attagccatt tttttgtaat gggaagtgta
    43141 aaatctgatt cggaaacgaa aatcgaagta ggcgggttgg attcgatccc tggtgaacta
    43201 cttacaccgt ttgattatgt agcactagga catttgcata atcaagctgc tttgagacag
    43261 gataatgctc gctatagcgg ttccccattg aaattctctt tatctgagat caaccaaaaa
    43321 aaaggcgtat ggatcgttga cctgacaaca ggcctggagt tgaattttag ggagatcgaa
    43381 cccctgcatg atattgaaga aataacagcg agtttcaaag aattgctgga tcctgccttt
    43441 tatcagtccg tcaatcggga gaattacatc tatatctatc tcactgatag aacgatcatc
    43501 ccgaatatga tgaaccagct tcggcaaata tatcctcgta ttttggggat tgaacgggca
    43561 aacggtcgag cagaacaaac aaagcgcaaa cgaaaagtac tagaaatgaa agatcctcaa
    43621 aaattagcag aagcattttt tagtgaaatg acggaagagc agctaactgc aaaccaagaa
    43681 aaatggctcg gagaaacgtt gcaagaaatc atggaaatgg aatgatcaag aatgaaaccg
    43741 aaaaaattac aacttaaaaa ttttggtcct tttatcaatg agaccgtaga tttttcacgt
    43801 ttgacagaag caccgctttt tttgatcagc gggaagacag gagctggcaa aacgacgatt
    43861 tttgatggga tcaccttcgc actttttggt gaaacttccg gaagacttcg ctctggaaaa
    43921 gagatgcgtt ctttgtttgc tacaccagac gaagaaacaa gcgtgacttt ttcttttgaa
    43981 catcagcaga tgagctatga aatcgaacga aaaccagaac aagttttagc aaaacgaaaa
    44041 ggaaacggaa caaaaaaaca ggcagccaaa gtaacgttga ccatttttga tgggaaagga
    44101 aaagaaataa aacaaatcac aaaacgtaca gaagcagatc agttgatcag agaactgatg
    44161 aatctcgatg cgaaacagtt ttctcaaatc gttttactac cccaaggaga attccgtaat
    44221 tttttggttt catcaagcag tgataaagag actgttttac gtcatttatt cggtactcaa
    44281 tttttccaac agttcaatga gcgattaaaa gaaaaagcaa aacaacagca acaaaaattg
    44341 gatcatttag agcaagagct gcatcttctg caaaaaaggt ttgttttagt caaagaagag
    44401 gaaccagcag cagggtttga agccgtttta gcccaatgga caaaccatca ggcaatactc
    44461 gaaaaacaaa tcacggaaga aaaagaagct ctaacggaac ttcaggaaaa acaaaagcaa
    44521 ctagaaaatt cctactatcg ttttgaaagc ttgaaaaaaa gttatgaaga aaaaacgata
    44581 ttaataaaca agcaaaagga attagctgct caaaaagacg aaatagagga aaagaaacga
    44641 tggattgggt attatgaatt tacgcaacga ttagtcgaac caatccagcg cctacaagaa
    44701 ataaaagttg aaaaaataga actgtcacaa aaaagtagtg agcaaacaaa gaaactagcg
    44761 atgactacgc agaattatga agagtggcaa aaaaatgaag caaaccgcgt acgccgacaa
    44821 acaaaaatca aagaagctgc tcaaaaactg caaaacaaac agatgatggt gccaattgtc
    44881 gaatccttac gtagtaaaaa acaagacgca gaacaattaa caatttcatt ggataaagaa
    44941 gaattgaatg ccgagaagct gtatcaaaat ctcgctatct atcaggaaag aactcgaatt
    45001 cttcaagaaa atttactgga tcaggaaaaa ctgcaagaag atcgtcttgc ttttggacag
    45061 ttaaaatatc tagatgaaaa gcagcaagaa atagaaaaac aaaaagcaaa agacactggg
    45121 tcgctcgcac agataagaga agaactcaaa aaagcaactg aagaaataac aaaaaatagt
    45181 cagctattga aagaacagac agaacaagca gaacagctga aaagccaatg ggcaaagcag
    45241 caaattgctc gtcttcagct ttttttgcgt ccaggggagc catgtcttgt ttgtggatca
    45301 acggaacacc ccatacaaca attaaaacac gaacagccaa ataaggaaga tatcttaaaa
    45361 gtagaacaac aactggcaga agctgagtct gctgtagaaa gaactcagca aatcattgcc
    45421 aaaagtgaag cacatgaaaa taatcttcaa caacaattat cagatttaga acaaaaaatc
    45481 atggcaacga atatacaatt ggctgaacaa gaagaacact tgcaacaggc tttgaaaaag
    45541 gcatttcctg agataacaga acaaaaaaca aaaacaactc ttgtagtaat cgaacaatct
    45601 ttagatagac gaaaaagcaa gatggccaat gcaagaatag agctggaaga aataagacaa
    45661 caagcagaaa agctcgaaca acaattagct gtctacaaac agcagcagac agaaaaaaat
    45721 aatcagctcc agcaactgca aggagaaatc aaaagtttag aacaacaatt gcaagatacg
    45781 gatagtaact gtttagaaga ggagatacga cgacttgaaa aacagttaga agaagactcg
    45841 aatcaactag ctgttgagca gaaagcagga gtgcaattgt tgcaagatct tcatacgctt
    45901 cggacacagc ttgatcttca acatgaacaa atagaaaaaa tagatgaaaa aatagaaaag
    45961 gaacaagaaa gaatagctaa aaagttagaa agccagtcgt atttttcaac aattgaagaa
    46021 atctgtgcat ttgcacaaca gcaagcacaa tataaagaaa accaacgtac agttacttct
    46081 tatcatgaag agcaattagt gacagctgac cggctgcgtc aattagaaaa tatccagcta
    46141 actgagacat tcccagatac agaagagatc agccaacagt tagaagaaat aagacgtatg
    46201 atcgaaataa agcaagaaaa gatatacggt ttacaagaac aaaaaattag taatcaaaaa
    46261 atctacgatg aatgtctttc gatttatcac acaagccaga cgaaattaga tgagcttacg
    46321 caattacagc agctttcgca aacattcaac ggagaaaatc ctaagaagac tagtttggaa
    46381 cggtatgtgc ttcaggttta tcttcaagaa gtgttacaag tagcaaatga tcatctccaa
    46441 cgtttaacga aaaatcgtta tcaatttgag ctagcggata ccattggcag ttatcgaggg
    46501 aaaaccggat tagaaatcaa tatctatgat gatcaggcag gtatgtctcg aagtgcgcat
    46561 accctgtctg gcggtgagag ttttattgca gcactttctt tagcattagc tcttgccgat
    46621 gtgatccaga cacaagctgg tggtgtagca atcgatgcat tgtttattga tgaaggattt
    46681 gggtcattag atgaagaagc tttggaaatg gcaatggaag ctttagaaac gatcgaaagt
    46741 gaaggaagaa tgatcggcat cattagtcat gtaagagaat tgaaagaacg agtattacaa
    46801 caaataagaa ttgatacaga aggtagcgga caaagcaaaa tacgctatca acttggataa
    46861 aaagggagat tggtaactat gaaatggagt attccagaaa aagtcattgc acgtggacgt
    46921 caatacttgc aagaaggccg agtgttatcg gttgtccctg accaagaaga aaacgtgtgg
    46981 catgcagaag tcttgggcag tgaattgtat atggttgatt tggatggtac agcaaaagag
    47041 atagattact gccaatgtcc ctattgggag gaacataaat attgtaagca tacagttgct
    47101 gtggaacttt atttacggtc gaaaaatcta tctcgtatca tgaaaaaaga ccagccaatg
    47161 ctagaaccgg taaaagcaac aagtgaggga gaaatcattg caaaaggttt ttctcgtcta
    47221 aaaacacaaa acaatcctca agcggtgcaa cctttgatta ttgaatacca agtagaaacg
    47281 attgagacta atcagtatca cccagagctt tctattttgg cactttactt gcgtatcggt
    47341 tcattggcat caccgaaaaa aacatatatc gtaaaaaaca tctatgattt tttacaagct
    47401 tacacagaaa aagaaactta cactgttaat aaacagtacc agtttcgtct agataaacgg
    47461 gcgtttcaaa aagaagatca aaaaatactc acgcatcttg caggaagtgc tcagacgcat
    47521 caattattag gtacgaacgg cttacaagtc aaaggaaaac tagataaaag atatctgctt
    47581 ctcccagtag aacaagcccg cttcctgtta gagcagatga atcagactac acgtttgcat
    47641 ctgcagataa atgaacaaaa cgatcaagga atacaatttt ccgatcaaaa caaaccttta
    47701 tcattcaaag tggaaaaatt tggagaagat tatttgctgc aagcattgaa tgattttgat
    47761 tttttcttta tgcattatca gtggggagtt atccaaggga cattttattc tctgacgaaa
    47821 tatcaacaaa cggtttatca aacttggaaa caattgattc gccgattgga gaaaccagaa
    47881 gtagtgttca agaaaaaaga attaccgtct ttgtttaaag agattatccc tctgctgtca
    47941 gagatcggcg acgtagctat tgcccctgca gtagaagagg aagtagcaga tatccccgtc
    48001 gaatttattt tctttttccg aaaagcaaaa ggaaaaatcc aagctcgagt cgatttcgtc
    48061 tatggcgaag tcatctattc gactgacccg aagcatgagg tctcgacaga acaggctttt
    48121 caggtgttac gtgacacagt agaagagaaa cgagtacttg atctattcag aatgtatcgc
    48181 taccagaaaa atgaaactgg ttatgaacgt ccattgccaa gcggggaaga actatatgcc
    48241 tttttccgca cagaactatc tgtcttccgt cagtttggtg aagtcagact tggaagaaaa
    48301 ttgcgagagt tgtatttaga tgcgcataaa catcaaccga aaatcgaagt aaccgagacc
    48361 ggttcatggc tcgatattcg attcgatgtg acagggatag aggagcaaga aatcgatcat
    48421 gtcctgcaaa gcttgctgag aaatgatgct ttttatacat tagaaaatgg tcaggttctt
    48481 tcttttgatt cagaagaatt tcaacaaaca agccaagtgt tgcaacaatt acgggaatcg
    48541 atacgtacag aagaaggaac gatccatgta cctaaaaatc aaggattgat cattcaaaat
    48601 caattggaaa aaagcaatgc tacttttagt gaatcgttcc aaacgatggt acaagatctc
    48661 attcatccag aaagatacca ggcacagctt cccaaaggat tgaatgcaac gatgagagat
    48721 tatcaaaagc aaggttttcg atggttgaag atgttaggtc attatcagtt tggcggtatt
    48781 ttagccgatg aaatgggact tgggaaaaca ctacagacaa ttgccttttt actttcggaa
    48841 aaagaagaac ggaaaagctt ctctgctttg atcgtagcgc ctgcgagctt aatttacaac
    48901 tggcaggcag aggtgagaaa attcgcccct tctttaagta tccaagtaat caatgggaat
    48961 aaaaaagaac gtgaagaatt actggctaaa gacacagata tccgagtgac ttcttatgcc
    49021 agcttaagac aggatctagc taattatcag tcgcaaaaaa ttgattattt gattcttgat
    49081 gaggcacaaa tggtcaaaaa tagcagtacg aaaactgcac aagcattgag agaattagct
    49141 gtacctcagc ggtttgcact gagtgggaca ccaatcgaga ataatttaga agaattgtgg
    49201 tcattgtttg caacgattat gccaggattt ttcccgacta aaacaaaatt cagggaactt
    49261 gccgcagaag aaattgcgca aatgattcga ccgtttattt tacggcgaga taaacaaact
    49321 gtgttgaaag acttgccgga aaaaacagag atgaatctat attctgcact tacagaagaa
    49381 caaaaaactg tttatttagc ttacttgcgt caaatgcgtg aagaaatcac atcaatggat
    49441 tctgaagcat tcaagaaaaa ccggatcggg atacttgctg gtctgacaag actgcgacaa
    49501 atttgctgcg atcctcgtct gtttattgaa gattaccaag gcggttccgg caagctcgaa
    49561 caagtaaaag atctactggt agctgccaaa gagaacaaac gaagagtttt gctgttttct
    49621 caatttacag ggatgctgac tatcttgcaa gaagagttag ccgagctagg gatctcgaca
    49681 ttttatttaa gaggcagtac gaaaccacaa gatcggttaa gtatggtaga cgcatttaat
    49741 gctggcgaaa aagatgtttt tctgatttcc ttaaaggctg ggggaactgg attgaatctc
    49801 acgggagcag atacggtcat cttgtatgac ctttggtgga atcctgccat tgaagaacaa
    49861 gctgctggac gtgcacatcg gatcggacaa aaaaatgtgg tagaagtgtg gcgtatgatc
    49921 tctgaaggaa cgattgagga acgcatggat tcactccagc aagaaaaacg cgaactgttc
    49981 caaaaagtga tccaaggtaa tgaagaacag ttgacgaaac tgactgaaga agacatccgc
    50041 atgattttaa gtgtaggaga aatcgaggag taagagactc gaaaaagcgt tcagtaatgg
    50101 gtaagaaagc ctttctaaag aagcgattgt ttatttgatt taaaaaatag caaggaggct
    50161 gggattccat tttatcccag cttccttgct atcatttttt tatttctatt tttaaaggtt
    50221 atacaaagat tgtcttcatt gtctctaaca gctgatcaaa agaagaaatc tcgatatcgc
    50281 aaattggagt ctgttcaatt ttgcgttctc gatggttgaa ccaaagcgct tgccagttag
    50341 cactttttgc acctagaaca tcattgtcgt aattatcgcc aacgtataag gtctcttctg
    50401 gaagcatatg aaattctttc tcagctagct gaaaaatctc tttttctggt ttttggaaac
    50461 ctgttgcttg agaaatgagc atattgcggg aaggaatcca attgttcaat tgaagttgct
    50521 tcagtttttt tgtctgatgg tcagtcggcc catttgtgat aattcctaat gggacattct
    50581 tttccttcaa gaaatcgagg gtttttttga cctcctcatg caagcagata ttatcaagtt
    50641 cttcctcgta aattttttga aataagaggc catcttcttc cgtaatatga gggtagtcta
    50701 aatcttttag tgattggctg atccgatgtg ctcgcatata ttctagtgtc caatctcctg
    50761 ccattacttt tgggaagttt tcatcactat gatggcggaa ccggatatat agtggatgca
    50821 tatctgcatc tgaaacaagc ggaacgactc ttttgaccgc gtttcgaaat ggctgctgct
    50881 gatcatacat cgtatcatca acatcaaaca caactgattt aatcaaaatt ttacacgcct
    50941 ttcggttttc attgattttt tcacaaatcc ttgactattg taacagaaaa aattgtctaa
    51001 aaaagctgat aaataaaggt ttttcttact atatttctat ttccttgaca gaataaggtt
    51061 tttatatttc agtttttttc actaaaaatc gtgaaacacg tcaataagtt tgatgaacaa
    51121 attaatcatt atggtagaag tcgattgatt tattttaatg caatctctgt ggaattttcg
    51181 aaagatttat ttttttaata cagtctcaat ataactattc aaacataaaa taacgttatt
    51241 tgatttattt gtttatagta aattttattt agtaatcatt gctttaaaat actacgctta
    51301 tataacagag aaaataagcg ttataataaa gaacagtatt atttaaaatg acagaaaaca
    51361 ttactattaa agaaataaaa aacataaaaa atcttaagaa atcggtttca tttagctttt
    51421 gagataaaat aatagtacag ttttatacgc tgtttcatat gtttagaaaa tttgaattag
    51481 atttgaaaac tctaattttt aaatgataaa aaaagcgaga atgctggttt tactgtatat
    51541 taaccttaga taactttcat ttttttaaaa aaattatgaa aaaaaggtag ctatttaaaa
    51601 gttgattatg tataatagaa acagatggga gattattatg atcttctgtt acaaaaaagt
    51661 gattcttatc acgaaaagga gtggtgcacg ttgttaacat tatatacttc cccaagttgt
    51721 acttcctgca gaaaggctcg tgcgtggttg caagaacatc agattccatt tgttgaacgt
    51781 aatatttttt cagaaccatt gaacagttct gaattaaaag cgattttaca aatgacagaa
    51841 gacggaacag aagaaatcat ctcgacacgt tccaaagtat tccaaaaact gaacatggat
    51901 ttagatgatc tgccgttaca agaattattg gaacttgtgc aaaacaatcc tggattgctt
    51961 cgccgtccaa tcatgattga tgataaacgt ctgcaagttg gttttaatga agatgaaatt
    52021 cgtcggttcc taccgcgcga tgtacgacaa ttagaattac gtcaagcaca attgatggct
    52081 ggattataga aggataatac gaaacttgga aaagactatt acaaagatag tttttccaag
    52141 tttttttgtt tttacaaaaa gtattcttga ttagatgtat aaaaaggtag tagaagatga
    52201 tgattgcacg aaaaatagag agggaaaatt agctgaaaag tcggctatat agtattcgtc
    52261 tgccaaaaat gttatagtta aataagatag cttgaaaggt tgaaaaatcc gctggtttta
    52321 ttaaattcgc ttaacagcga gatttttttt ctttacattt aagctgattt cgctacaatg
    52381 aatctatatt aaacattgtg gcaaagtgag gtgtagcaaa atggaaatgg aacatattaa
    52441 tgaaaatacg atccgtgtac taattggtca tgaagattta gaggaacggg gcgtttcatt
    52501 tttggattta cttggcaatc acaaagaaat cgaaaatttc ttttatagta ttttggaaga
    52561 agttgatatc gaagaggagt tccgaggaag cgaagctgtc actttccaag ttttgccaaa
    52621 aggagacgga ttagaactgt ttatcagtaa aaatcttccg gatgaagaaa tttctcaatc
    52681 agaagattct actgttgatt cagaagatgt gagtgacttt cttcgtcagc agattattgg
    52741 cagcgatccg gaggaagaat tatctggaag cgccctagaa gaacaggaaa gacaagcaac
    52801 ttttgctttt gaagattttg aacaagtgat ccaacttgca acagatgtcg aactagagtc
    52861 tgcttggact gatttgtatt tattcgaaga gcgctattac ctagtcgttc acttctggat
    52921 ggaaaatctc aaccaagcgg atgtagagaa tcagattgct cgaattttgg agtttgctga
    52981 aaagagcgat cgtacaccag aaacattgaa tgaatatgga caatgtctga tggcgcgtaa
    53041 tgctatcgag cgaacgaaat tttattttgt ataaatcagc attatagtaa gagactgtga
    53101 caaaaattgt gtcgcagtct ttttttcgta taaatgtgtt caaaagcttg catctgcggt
    53161 aacaagccca accaaacgaa aaatattggg aactattttt gtttagctgt tcttattact
    53221 tgatgcagaa tagctttttc acgccctctt ttttcgtgta aataaattct tagacgtaaa
    53281 taagttcaga gggagaaaaa tgctgcttgc aatgaatgaa tataataagt gctgttttgc
    53341 taaacatgca gaaaaaggaa agaaatatta ttgtcgtggc tgtcgaaaaa gagtgatttt
    53401 gaaaaaggga aagaaaaaat gtgctcattt tgcccatcaa aaatcagata actgttcggt
    53461 ctttagtgaa agagaatcaa aagagcactt acagttaaag gaatgcttca tggattggct
    53521 gggacagtca gtagaaccag tatttttgga agcctatttg ccgaggttgc ggcaaaggcc
    53581 ggatattttg ttggcgaatc tagcaataga aatccaatgt tctagactgt ctcaccagag
    53641 atttattgaa agaacccaaa attatttgaa taacagttac caagtatggt ggatacttgg
    53701 taattctttt cttggacaat cgcaattctc attgatagaa aaaagttgct gctactataa
    53761 tagaaaaaga ggagtgcatt gctggaaagc tgatctcaag aaacaaaagc tttatttgta
    53821 tcatcatatt acagagactg tatcagggca tatttccttt tgcagtagct gctggacttt
    53881 ttctagtagg gaccttaaag aaatattcac tagtaacgaa attaaaatga accaaatgaa
    53941 aaaaatagaa aaagtgagtg aagatgggaa gaaatggctg acacgccaac ttattcacaa
    54001 gcaaaagaat acagtatcca tacaagaaca atgctacttg cgtcataaac atcttttgca
    54061 tctatcatcg tggatctatc aaaaaagtcg gtttttcttt tatttacaag aacaggtttt
    54121 tctttatcga atgttgtacg aagaagcctt ggaaaaccag aaagttcctg atttcaactc
    54181 atggctttgc caaataaaag aacataaaag ggaatggctt tttcctatga ttgatgaaga
    54241 gatggtctat cagcagtttt ttaacgaatg catacacttg tcttctttga aaaaatagta
    54301 agtataaaaa taggctagga atcggttttc tatgtaaaac aagatttagt tatgctaaaa
    54361 ttgatggaag cagacacatg aatgagtaga aaagttagat gctgtgacat gtggatgtta
    54421 gactatgatc tattttgata gatagagcta agggaagaaa aggagtggat ttcatggaag
    54481 taaagcagtt gccaaaacga gaagaattgc ctgaaaattt aacttgggac ttgaccaaga
    54541 tcttttcaag cgaccaagag tttgatgaga aatatttgga attatcagaa gagttaaaac
    54601 aatctgaaaa acacaaagga acacttgatc aaggcgcttc tcaattttta aatgcgattg
    54661 aattcgtatt gagggtttat cgccaaactg aagtcattta tgtatatgcg caccttaaaa
    54721 acgatcaaga cactggaaat acagattacc aagcgcttta tgcaagagca agcagtctgt
    54781 tttcgaaagt tagtgaagcc gtttcctggt ttgaaccaga aatattgcaa ttgtcagatg
    54841 accagatttg gcaatatttc aaagaagaac caaaattgga agtctatcgc cattatatcc
    54901 agcaaatagt agataatcga gcccatgtct tatctgctga gcaggaatct cttcttgctg
    54961 gagcaggtga aatctttgat gcttcaagtg atacatttgc tgttttgaat aatgcagatc
    55021 tagtttttcc aacgattgaa ggagaaaatg gtgaaatagt ccaattatct catggcgtgt
    55081 atggtcagtt gctagaaagc acggatcgaa gggtgcgcga agcagcattt aaggggttgt
    55141 acagtgttta cgaacaattt agaaatacat ttgcttctac tttaggcaca catataaaag
    55201 gacataattt taaagcgaaa gtccgtaatt acagctctgc cagagaagcg tctttgagca
    55261 ataatcatat tcctgaaagt gtatacgata ctttggtaga cgtggtaaac aagcatttgc
    55321 ctttgttaca tcgatacatg gaattacgga aacgtttatt agaagtggaa aaactgcaca
    55381 tgtatgatct ttatacaccg gtcttagggg aagctccaat tacctttacg tacgaagaag
    55441 caaaagaaaa agctttagaa gcactgaaac caatgggtga agaatacatg gccatcgtag
    55501 aaaaagcatt ctctgaacgt tggatcgatg ttgtcgaaaa taaagggaaa cgaagcggtg
    55561 cttattcttc gggaagctat gacacaaatc catatatttt attgaattgg catgatacgc
    55621 tggatcagct atttacgctt gtccacgaaa tgggacatag tgttcatagt tatttcactc
    55681 gttcgaacca gccttatgtg tacggcgact actccatctt tttagcagaa attgcttcga
    55741 caacgaatga aaatatccta acggagtatt tattggaaac agaaaaagac cctcgtgtac
    55801 gggcttatgt actcaaccat tacttggatg ggtttaaagg aacagttttc cgccagacac
    55861 aattcgctga attcgagcat ttcatgcata cggaagatga aaaaggtgtg ccattgacta
    55921 gtgaatacct aagtgatagt tatggtaaat tgaatgcaaa atattatggt ccagcagtcg
    55981 aagaagaccc agaaattaaa ttcgaatggt cacggatacc gcatttttat tataattact
    56041 atgttttcca atactcgact ggcttttctg ctgcttcagc actggcgaag aaaatactaa
    56101 accaggaacc agaggcacta gagaactact tggcttacct aaaagcaggt aacagcgatt
    56161 atcctgtgga agtaatgaaa aaagcaggag ttgatatgac acaggctgca tatattgaag
    56221 atgcaatgtc gatgtttgaa caacgtctaa atgaattaga agaattgatc gatcgtttat
    56281 aaggctttct atttttgatt ttctcgaata gaaacgaaaa aaatacgtcg gctctcttgt
    56341 aagggagtcg acgtattttt t
//
LOCUS       DACBZK010000008        54551 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.008, whole genome shotgun sequence.
ACCESSION   DACBZK010000008 DACBZK010000000
VERSION     DACBZK010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54551
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.008"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            300..608
                     /gene="rpsJ"
                     /locus_tag="IVD66_000558"
     CDS             300..608
                     /gene="rpsJ"
                     /locus_tag="IVD66_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HAP6144804.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            639..1268
                     /gene="rplC"
                     /locus_tag="IVD66_000559"
     CDS             639..1268
                     /gene="rplC"
                     /locus_tag="IVD66_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HAP6144805.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGSVPGAKKSLITIKSAVKAK"
     gene            1296..1919
                     /gene="rplD"
                     /locus_tag="IVD66_000560"
     CDS             1296..1919
                     /gene="rplD"
                     /locus_tag="IVD66_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HAP6144806.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            1919..2209
                     /gene="rplW"
                     /locus_tag="IVD66_000561"
     CDS             1919..2209
                     /gene="rplW"
                     /locus_tag="IVD66_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HAP6144807.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            2248..3081
                     /gene="rplB"
                     /locus_tag="IVD66_000562"
     CDS             2248..3081
                     /gene="rplB"
                     /locus_tag="IVD66_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010747214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HAP6144808.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            3124..3402
                     /gene="rpsS"
                     /locus_tag="IVD66_000563"
     CDS             3124..3402
                     /gene="rpsS"
                     /locus_tag="IVD66_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HAP6144809.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            3425..3772
                     /gene="rplV"
                     /locus_tag="IVD66_000564"
     CDS             3425..3772
                     /gene="rplV"
                     /locus_tag="IVD66_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HAP6144810.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            3786..4442
                     /gene="rpsC"
                     /locus_tag="IVD66_000565"
     CDS             3786..4442
                     /gene="rpsC"
                     /locus_tag="IVD66_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HAP6144811.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            4445..4879
                     /gene="rplP"
                     /locus_tag="IVD66_000566"
     CDS             4445..4879
                     /gene="rplP"
                     /locus_tag="IVD66_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HAP6144812.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            4869..5057
                     /gene="rpmC"
                     /locus_tag="IVD66_000567"
     CDS             4869..5057
                     /gene="rpmC"
                     /locus_tag="IVD66_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HAP6144813.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            5082..5348
                     /gene="rpsQ"
                     /locus_tag="IVD66_000568"
     CDS             5082..5348
                     /gene="rpsQ"
                     /locus_tag="IVD66_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HAP6144814.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            5406..5774
                     /gene="rplN"
                     /locus_tag="IVD66_000569"
     CDS             5406..5774
                     /gene="rplN"
                     /locus_tag="IVD66_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HAP6144815.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            5811..6119
                     /gene="rplX"
                     /locus_tag="IVD66_000570"
     CDS             5811..6119
                     /gene="rplX"
                     /locus_tag="IVD66_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HAP6144816.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            6147..6686
                     /gene="rplE"
                     /locus_tag="IVD66_000571"
     CDS             6147..6686
                     /gene="rplE"
                     /locus_tag="IVD66_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HAP6144817.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            6705..6890
                     /locus_tag="IVD66_000572"
     CDS             6705..6890
                     /locus_tag="IVD66_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HAP6144818.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            6926..7324
                     /gene="rpsH"
                     /locus_tag="IVD66_000573"
     CDS             6926..7324
                     /gene="rpsH"
                     /locus_tag="IVD66_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HAP6144819.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            7356..7892
                     /gene="rplF"
                     /locus_tag="IVD66_000574"
     CDS             7356..7892
                     /gene="rplF"
                     /locus_tag="IVD66_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HAP6144820.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKESKTGK"
     gene            8053..8409
                     /gene="rplR"
                     /locus_tag="IVD66_000575"
     CDS             8053..8409
                     /gene="rplR"
                     /locus_tag="IVD66_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HAP6144821.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            8430..8930
                     /gene="rpsE"
                     /locus_tag="IVD66_000576"
     CDS             8430..8930
                     /gene="rpsE"
                     /locus_tag="IVD66_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HAP6144822.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            8945..9124
                     /gene="rpmD"
                     /locus_tag="IVD66_000577"
     CDS             8945..9124
                     /gene="rpmD"
                     /locus_tag="IVD66_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HAP6144823.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            9168..9608
                     /gene="rplO"
                     /locus_tag="IVD66_000578"
     CDS             9168..9608
                     /gene="rplO"
                     /locus_tag="IVD66_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HAP6144824.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            9608..10903
                     /gene="secY"
                     /locus_tag="IVD66_000579"
     CDS             9608..10903
                     /gene="secY"
                     /locus_tag="IVD66_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HAP6144825.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            10965..11612
                     /locus_tag="IVD66_000580"
     CDS             10965..11612
                     /locus_tag="IVD66_000580"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HAP6144826.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            11803..12021
                     /gene="infA"
                     /locus_tag="IVD66_000581"
     CDS             11803..12021
                     /gene="infA"
                     /locus_tag="IVD66_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HAP6144827.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            12054..12170
                     /gene="rpmJ"
                     /locus_tag="IVD66_000582"
     CDS             12054..12170
                     /gene="rpmJ"
                     /locus_tag="IVD66_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HAP6144828.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            12188..12553
                     /gene="rpsM"
                     /locus_tag="IVD66_000583"
     CDS             12188..12553
                     /gene="rpsM"
                     /locus_tag="IVD66_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HAP6144829.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            12581..12970
                     /gene="rpsK"
                     /locus_tag="IVD66_000584"
     CDS             12581..12970
                     /gene="rpsK"
                     /locus_tag="IVD66_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HAP6144830.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            13050..13988
                     /locus_tag="IVD66_000585"
     CDS             13050..13988
                     /locus_tag="IVD66_000585"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HAP6144831.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            14016..14396
                     /gene="rplQ"
                     /locus_tag="IVD66_000586"
     CDS             14016..14396
                     /gene="rplQ"
                     /locus_tag="IVD66_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HAP6144832.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            14668..15507
                     /locus_tag="IVD66_000587"
     CDS             14668..15507
                     /locus_tag="IVD66_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP6144833.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            15483..16352
                     /locus_tag="IVD66_000588"
     CDS             15483..16352
                     /locus_tag="IVD66_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP6144834.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTADELAD
                     AIVHYAGGNAHDE"
     gene            16342..17139
                     /locus_tag="IVD66_000589"
     CDS             16342..17139
                     /locus_tag="IVD66_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAP6144835.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            17342..18088
                     /gene="truA"
                     /locus_tag="IVD66_000590"
     CDS             17342..18088
                     /gene="truA"
                     /locus_tag="IVD66_000590"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAP6144836.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(18421..21090)
                     /locus_tag="IVD66_000591"
     CDS             complement(18421..21090)
                     /locus_tag="IVD66_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAP6144837.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(21328..21516)
                     /locus_tag="IVD66_000592"
     CDS             complement(21328..21516)
                     /locus_tag="IVD66_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HAP6144838.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            21786..22148
                     /locus_tag="IVD66_000593"
     CDS             21786..22148
                     /locus_tag="IVD66_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP6144839.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            22200..23882
                     /locus_tag="IVD66_000594"
     CDS             22200..23882
                     /locus_tag="IVD66_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HAP6144840.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            23999..26035
                     /gene="recG"
                     /locus_tag="IVD66_000595"
     CDS             23999..26035
                     /gene="recG"
                     /locus_tag="IVD66_000595"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HAP6144841.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            26084..27085
                     /gene="plsX"
                     /locus_tag="IVD66_000596"
     CDS             26084..27085
                     /gene="plsX"
                     /locus_tag="IVD66_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HAP6144842.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            27207..27449
                     /gene="acpP"
                     /locus_tag="IVD66_000597"
     CDS             27207..27449
                     /gene="acpP"
                     /locus_tag="IVD66_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAP6144843.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            27717..28721
                     /locus_tag="IVD66_000598"
     CDS             27717..28721
                     /locus_tag="IVD66_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6144844.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            28722..29666
                     /locus_tag="IVD66_000599"
     CDS             28722..29666
                     /locus_tag="IVD66_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6144845.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            29666..30628
                     /locus_tag="IVD66_000600"
     CDS             29666..30628
                     /locus_tag="IVD66_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6144846.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            30655..31569
                     /locus_tag="IVD66_000601"
     CDS             30655..31569
                     /locus_tag="IVD66_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6144847.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            31595..33376
                     /locus_tag="IVD66_000602"
     CDS             31595..33376
                     /locus_tag="IVD66_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6144848.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            33724..34410
                     /locus_tag="IVD66_000603"
     CDS             33724..34410
                     /locus_tag="IVD66_000603"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAP6144849.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            34430..38011
                     /gene="smc"
                     /locus_tag="IVD66_000604"
     CDS             34430..38011
                     /gene="smc"
                     /locus_tag="IVD66_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HAP6144850.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            38020..38829
                     /locus_tag="IVD66_000605"
     CDS             38020..38829
                     /locus_tag="IVD66_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP6144851.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            38840..39838
                     /gene="ftsY"
                     /locus_tag="IVD66_000606"
     CDS             38840..39838
                     /gene="ftsY"
                     /locus_tag="IVD66_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HAP6144852.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            40025..42292
                     /gene="gshAB"
                     /locus_tag="IVD66_000607"
     CDS             40025..42292
                     /gene="gshAB"
                     /locus_tag="IVD66_000607"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HAP6144853.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(42381..42833)
                     /locus_tag="IVD66_000608"
     CDS             complement(42381..42833)
                     /locus_tag="IVD66_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HAP6144854.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKSNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            42983..43933
                     /locus_tag="IVD66_000609"
     CDS             42983..43933
                     /locus_tag="IVD66_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAP6144855.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            43926..44885
                     /locus_tag="IVD66_000610"
     CDS             43926..44885
                     /locus_tag="IVD66_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAP6144856.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            44882..45637
                     /locus_tag="IVD66_000611"
     CDS             44882..45637
                     /locus_tag="IVD66_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6144857.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            45660..46613
                     /locus_tag="IVD66_000612"
     CDS             45660..46613
                     /locus_tag="IVD66_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6144858.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(47257..47553)
                     /locus_tag="IVD66_000613"
     CDS             complement(47257..47553)
                     /locus_tag="IVD66_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HAP6144859.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            47908..48264
                     /locus_tag="IVD66_000614"
     CDS             47908..48264
                     /locus_tag="IVD66_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAP6144860.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            48274..49173
                     /locus_tag="IVD66_000615"
     CDS             48274..49173
                     /locus_tag="IVD66_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HAP6144861.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            49690..50421
                     /locus_tag="IVD66_000616"
     CDS             49690..50421
                     /locus_tag="IVD66_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAP6144862.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            50566..52593
                     /locus_tag="IVD66_000617"
     CDS             50566..52593
                     /locus_tag="IVD66_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lectin"
                     /protein_id="HAP6144863.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            52701..53798
                     /locus_tag="IVD66_000618"
     CDS             52701..53798
                     /locus_tag="IVD66_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAP6144864.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            54105..>54551
                     /locus_tag="IVD66_000619"
     CDS             54105..>54551
                     /locus_tag="IVD66_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP6144865.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT        18232 a         9640 c        11701 g        14978 t
ORIGIN      
        1 aaaagacagg agtattataa atagaagaaa cacgaaataa aagagtcagt attttctaaa
       61 tgaaacttta tgaaaacaaa atgtttttta caagaaaaag ccttgctttg tgagtttata
      121 tatattataa tgacaaaggt gcgtttactt tagtgaattg cacagacgta atcagaatga
      181 tttcgtcggc taagaaacga gaggttgcga cacgcccgga cgctttgcca cgaacgagcg
      241 tgacggaaat tttcgtggag ctatgtctac ttttcaaaat aggcgaagga gggaacaaga
      301 tggcaaaaca aaaaattcgt atccgtttaa aagcgtatga acaccgtatt ttagatcaat
      361 cagcggataa aatcgtggaa actgcaaaaa gaactggagc tagcgtgtct ggtccaattc
      421 cattaccaac tgaacgcagt ctttacacaa tcatccgtgc gactcataaa tacaaagatt
      481 cacgcgaaca attcgaaatg cgtacacaca aacgtcttat cgacattgtg aacccaacac
      541 caaaaactgt tgatgctttg atgaagctag acttaccatc tggtgtaaac atcgaaatca
      601 aattataaaa ctaaaacaaa aataatggag gtgtactcat gaccaaagga atcttaggga
      661 aaaaagtggg aatgacacaa atcttcactg aatctggtga attaattcca gtaactgttg
      721 tagaagctac tccaaacgta gtactacaag tgaaaacaat ggaaacggat ggctacgaag
      781 ctattcaagt tggttaccaa gatatgcgtg aagttttatc aaacaaacct gcgaaaggtc
      841 atgttgcaaa agcaaacacg gctcctaagc gcttcattcg tgaattcaaa aatgttgagc
      901 taggagaata tgaagtagga aaagaaatta cagtagatgt tttccaagca ggagacatta
      961 ttgatgtaac aggtactacg aaaggtaaag gattccaagg ggttatcaaa cgccacggac
     1021 aaagccgcgg accaatggct cacggttctc gttaccatcg tcgtcctggg tcaatgggtc
     1081 cagttgcacc taaccgtgta tttaaaaaca aacgtcttgc tggccgtatg ggtggcaacc
     1141 gcgtaactat ccaaaacttg gaagttgtac gtgtcgatgc agaaagaaat gttatcttga
     1201 tcaaaggtag tgttcctgga gctaaaaaat ctttaattac tatcaaatca gctgtgaaag
     1261 ctaaataatt gtaggaagaa aggaggaact aaggaatgcc gaatgtagca ttattcaaac
     1321 aagatggaag ccaaaacggt gaaatcacac ttaacgaaga aatcttcgga attgaaccta
     1381 atgaaagtgt tgtttacgat gcaatcgtaa tgcaacgtgc gtcattaaga caaggaacac
     1441 acgcggttaa aaaccgtagc gctgttcgcg gcggcggacg taaaccatgg cgtcaaaaag
     1501 gaacaggtcg tgcacgtcaa ggatctatcc gctcaccaca atggcgtgga ggtggcgtag
     1561 tctttggacc aacaccacgt tcttacagct acaaacttcc taaaaaagtt cgtcgtttag
     1621 caatgaaatc tgtattgtca gaaaaagttg ctgaaaacaa cttggtagca atcgaaggct
     1681 tgaacttcga cgcaccaaaa acaaaagaat tcaaacaagt tcttgctaac ttatctatcg
     1741 actctaaagt attggttgtt ctagaaaaag gtaacgactt tgctgcttta tcagcacgta
     1801 acttaccaaa cgtttctgta gtaacttctg ataatgtgag tgtgctagac gttgtatcaa
     1861 atacaaaagt gttagcaaca caaactgctc ttactcaaat tgaggaggtg cttgcataat
     1921 gaacttacta gacgtaatca aacgcccagt gatcactgaa aaatcaatgc ttgccatgga
     1981 tgacaagaaa tacacttttg aagtggacac tcgcgcaaac aaaactttag taaaacaagc
     2041 ggtagaagct gcttttgacg ttaaagtcaa aaacgtgaac atcgtgaacg tacgtgcgaa
     2101 attcaaacgt atgggcaaat atgcaggata tacaaaaaaa cgtcgcaaag cgatcgttac
     2161 attgactgaa gattcaaaag aaatccaatt attcgaagct gctgaataag cactaataga
     2221 taactcatta aattaggagg gaaaaacgtg gcgattaaaa agtacaaacc tacctcaaat
     2281 ggtcgtcgta acatgacagg ttctgatttt gctgaaatca caacatcaac acctgaaaaa
     2341 tcattgttac aaccattgaa aaaccatgct ggacgtaaca acaacggccg catcactgta
     2401 cgtcatcaag gtggcggaca caaacgccaa tatcgcgtga tcgacttcaa acgtaacaaa
     2461 gataacgttg ttgcaactgt tcaaacgatc gaatatgatc caaaccgttc agctaacatc
     2521 gcgttagtac actatgaaga tggagtgaaa gcttacatct tagcacctaa aggactagaa
     2581 gtgggtatga aacttgtttc aggtccagaa gcagatatca aagtcggaaa tgctcttcca
     2641 ttagaaaaca ttccagttgg tactgttatc cacaacattg aaatgaaacc tggtaaaggt
     2701 ggacaattga tccgttctgc tggtacaagt gctcaagtac ttggtaaaga aggcaaatac
     2761 gtattgatcc gcttgaactc tggtgaagtt cgtatgatct tagctgcatg ccgtgctaca
     2821 atcggttctg taggtaacga acaacacgaa ttaatcaaca tcggtaaagc tggacgctct
     2881 cgttggatgc gtaaacgccc aactgtacgt ggtagcgtaa tgaaccctaa tgatcaccca
     2941 cacggtggtg gtgaaggtaa agctcctatc ggacgtaaag caccagtttc tccttggggt
     3001 caaccagctc ttggttacaa aactcgtaac aaaaaagcta aatcagacaa acttattgtt
     3061 cgtcgtcgca aaaataaata attactttga ccatgtgtcg cacattttga gaggaggttc
     3121 accatgggtc gtagtttaaa gaaaggacct tttgtcgatg agcatttaat gaaaaaagtt
     3181 gaagctcaag caggggttga aaagaaaaaa gttatcaaaa cttggtcacg ccgttcaaca
     3241 gttttcccaa gttttgttgg atataccatc gcagtttatg atggacgtaa acatgtacca
     3301 gtttacatcc aagaagacat ggtaggacac aaattaggtg aatttgcacc tacaagaact
     3361 tatcgtggac atgctgctga cgataagaaa acgaaacgct aatttgaggg gaggataaat
     3421 ccaaatggca gaacaaatca catcagctaa agcaactgca aaaacagttc gcacttcacc
     3481 tcgaaaagcc cgtttagtaa ttgaccttat cagaggtaaa agtgtcgcag atgcaatttc
     3541 aatcttgaaa ttcacaccaa acaaatctgc tggaatcatt gaaaaagtat tgatgtcagc
     3601 agttgcgaat gcagaaaata actttgactt agatgttgaa aacttggtag taagcgaagc
     3661 ttttgttaac gaaggaccta caatgaaacg tttccgtcct cgtgcaaaag gatcagcttc
     3721 tccaatcaac aaacgtacaa gtcatatcac ggtagtcgta tcagaaaaat aaggagggat
     3781 aatcagtggg tcaaaaagta catccaattg gaatgcgtgt aggcatcatc cgcgactggg
     3841 atgctaaatg gtatgctgaa aaagagtatg ctgagttctt acacgaagat ttaagaatcc
     3901 gtaaatttat ttcaactaaa cttgctgatg ctgctgtatc aacagttgaa atcgaacgcg
     3961 caacaggtcg cgtaaacatt tcaattcaca cagctaaacc aggtatggtt attggtaaag
     4021 gcggttctga agtcgaaagc ctaagaaaag aattaaacaa attaactggt aaaagaatcc
     4081 atatcaatat cgtggaaatc aaaaaaccag atctagatgc aaaattagta ggtgaaggaa
     4141 tcgcacgtca attagaaaac cgtgttgctt tccgtcgcgc tcaaaaacaa gccatccaac
     4201 gctcaatgcg tgctggcgct caagggatca aaactcaagt atctggtcgt ctaaacggag
     4261 cagatatcgc tcgttcagaa ggatactcag aaggaactgt tcctcttcat actttacgtg
     4321 cggacattga ttacgcatgg gaagaagcag atacaacata cggaaaacta ggagttaaag
     4381 tgtggatcta tcgtggagaa attcttccaa ctaaaaaaaa cactgagaaa ggagggaaat
     4441 aatcatgtta gtacctaaac gtgtaaaaca ccgtcgtgaa ttccgcggaa aaatgcgcgg
     4501 ggaagctaaa ggcggaaaag aagtagcatt cggtgaatac ggtttgcaag ctgttgattc
     4561 acattggatc acaaaccgcc aaatcgaagc tgctcgtatc gcaatgactc gttacatgaa
     4621 acgtggtggg aaagtatgga ttaaaatttt ccctcacaaa tcttatactg ccaaagcaat
     4681 tggggtacgt atgggttctg gtaaaggggc acctgaagga tgggttgcac cagtaaaacg
     4741 tggtaaaatc atgtttgaaa tcgcaggcgt tcctgaagaa gtagctcgtg aagcgttacg
     4801 tctagcttct cacaaattac caatgaaaac taagatcgta aaacgtgagg aaatgggtgg
     4861 tgaatcgaat gaaggttaaa gaaatcagag aattaaccac tgccgaaatg cttgatcaag
     4921 aaaaacaatt aaaagaagaa ttgtttaatc ttagattcca attagcaaca ggtcaattag
     4981 aaaacactgc acgtattaaa gaagtacgta aatcgattgc acgcatcaaa actgtgttgc
     5041 gtgaacaagc taagtaatta tggaaggagg ccattaagcg tatgactgaa ggaagaaatc
     5101 aacgcaaagt ttatcaaggt cgcgtggttt cagacaaaat ggataaaaca attaccgttg
     5161 ctgtcgaaac aaagaaaaac caccctatct atggcaaacg catgaactat tctaagaaat
     5221 acaaagtgca tgatgaaaac aacacagcaa aagttggcga catcgtgaga attatggaaa
     5281 ctcgtccatt atcagctaca aaacgtttcc gtttgttgga agtagtcgaa gaagcagtta
     5341 ttatctaata acacgagatt ttcctatata gattgaatgc aaaatctgaa aggaggatac
     5401 acaacgtgat ccaagcagaa agtcgtttaa aagtcgctga taactcaggc gcacgtgaaa
     5461 ttttgacgat caaagtcctt ggtggatctg gtcgtaaaac tgctaacatc ggtgatgtga
     5521 tcgttgctac ggttaaacaa gcaacgccag gtggggttgt caaaaaaggt gacgtcgtta
     5581 aagccgttat cgttcgaaca aaatcaggag ctcgtcgtac agacggttca tatattaaat
     5641 ttgatgaaaa tgctgcagtg attattcgtg atgataaaag ccctcgtgga acacgtatct
     5701 ttgggccagt tgcacgtgaa ctacgtgaaa acaacttcat gaagatcgtt tcactagcac
     5761 cagaagtttt ataatcttga gacacttatc aaaggaggtg cgaaacagtt atgtttgtta
     5821 aaaaaggcga taaagttaaa gttatcactg gaaaagacaa aaacaaagaa ggcgttgtac
     5881 tagcagcgtt cccgaaaaaa gataaagtta ttgtcgaagg tgtaaatgtc gttaaaaaac
     5941 accaaaaacc ttctcaagct gctcctcaag gtggaattgt tgagatggaa gcgccaattc
     6001 atgtttctaa cgtgatggtg gttgactcta ctggtgtagc tggccgagtt ggctacaaag
     6061 aagtagacgg caaaaaagtc cgtgtttcta aaaaaaccgg tgaagtttta gataaataaa
     6121 agtttaagga aggagggtct tactgaatga accgcctaaa agaaaaatat cttaaagaag
     6181 taactccatc attgatggaa aaatttaact atagctctgt tatgcaaaca cctaaagttg
     6241 aaaaaatcgt catcaacatg ggtgttggtg atgcggtatc aaacgctaaa aacttagata
     6301 aagcagttga agaattaact ttgatcactg gtcaaaaacc aatgattaca aaagctaaaa
     6361 aatcaatcgc tggattccgt ttacgtgaag gaatgccaat tggtgcaaaa gttacattgc
     6421 gcggagaaag aatgtacgaa ttcttagaca aattggtttc tgtttcacta ccacgtgtac
     6481 gtgacttcca tggtgtaagt aaaaaagcct ttgacggtcg tggaaactat actttaggta
     6541 ttaaagaaca attgatcttc ccagaagtag attatgattt agtagataaa gtacgtggta
     6601 tggacatcgt tattgtaaca acagcaaact ctgatgaaga atctcgtgag ttgttgacac
     6661 aattaggcat gccattccaa aaataattaa aggaggcgaa ctacgtggct aaaaaatcaa
     6721 tgattgctaa aaacaaacgt cctgcaaaat tttcaacaca agcttatact cgttgcgaac
     6781 gttgcggacg tccacattca gtttatcgta agttccatct ttgccgtatt tgcttccgcg
     6841 aacttgccta taaaggtcaa attcccggcg tgaagaaagc tagctggtaa aaagtaaatt
     6901 cgcataagaa ggaggtaaaa gatcaatggt catgacagat ccaattgcag attttctaac
     6961 tcgtatccgt aacgcaaaca tggttaaaca tgagtcttta gaagtacctg catcaaaaat
     7021 taaacgtgac atcgctgaaa tcttgaaacg tgaaggtttc gttcgtgatg ttgaatacat
     7081 cgaagatgac aaacaaggcg tgatccgtgt tttcctaaaa tttggtaaaa acggcgaacg
     7141 tgttatcaca aacttaaaac gtatctctaa accaggtttg cgtgcttatg tcaaagctga
     7201 cgaagtacca aaagtattga acggtttagg tatcgcaatc atttcgactt ctgaaggtgt
     7261 tgtcactgat aaagaagctc gtgaaaaaaa tatcggcggc gaagttatcg cttacgtatg
     7321 gtaatcaagt agaatctaca aggaggtgtc tttaagtgag ccgtatcgga aataaagtcg
     7381 ttgttatccc tgaaggagta acagttactc aagacggaaa caacgttaca gttaaaggac
     7441 caaaaggtga attgactcgt actttttcag cagatatcaa aatgaatatc gaaggaaacg
     7501 aagtaacttt cactcgtcca aacgacagta aagaaatgaa aacaattcat ggaacaactc
     7561 gtgcgaactt caacaacatg gttgtaggtg tcagcgaagg tttccaaaaa gcgttagaac
     7621 taatcggggt tgggtaccgt gcacaattac aaggatcaaa acttgtattg aacgttggtt
     7681 actcacatcc agtagaaatc acaccaccag ctggagtaac tgttgaagta ccagctaaca
     7741 cacaagtaat tgttaaaggt gcgaacaaag aagaagttgg cgaattagct gcaaacattc
     7801 gtggaactcg tcctccagaa ccttataaag gtaaaggtat tcgttatgtt ggcgaatatg
     7861 tacgccgtaa agaaagtaaa actggtaaat aatcgtttag aaaaattgca tagaagccag
     7921 cagcaggaaa aaggcatttg gctgaagttt accttcaaaa aaatacattt ttacttgtgc
     7981 cgcagcttct atttttcgaa acgtatttac tgcttgaaat agtagtacaa taaaaataaa
     8041 gaggtgacaa ttgtgattac aaaaccagat aagaacaaaa cacgtcaaaa gagacatcgt
     8101 cgtgtacgta acaatatctc tggtactgct gagcgcccac gcttgaacgt ttttcgttct
     8161 aacaaaaaca tctacgctca aattattgat gacgtagcgg gtgtaacgct agcaagtgcc
     8221 tctaccttgg ataaagaaat ttcaggtgga acaaaaacag aagcagcaca agctgtcggt
     8281 aaactagttg ctgaacgtgc agctgaaaaa ggcattaaag tagtagtctt tgaccgtggt
     8341 ggataccttt accatggccg tgtgcaagct ttagctgaag ctgctcgcga aaatggacta
     8401 gaattttaga agaaggagga ataccattca tggtttatat cgatccaaaa catttggaat
     8461 tagaagaccg cgttgttgca attaaccgtg taacaaaagt tgttaaaggt ggacgtcgtc
     8521 tacgttttgc tgctttagtt gttgtcggtg acaaaaacgg acacgtaggg tttggtacag
     8581 gtaaagctca agaagttcct gaagcaatcc gtaaagcaat tgaagatgcg aagaaaaact
     8641 tagttgaagt acctatggtt ggttcaacaa tcccacacga agtaatcggt gcttttagtg
     8701 gtggtagaat cctaatgaaa cctgctgtag aaggttctgg ggttgctgct ggtggaccag
     8761 ttcgtgccgt attagaatta gctggggtag cagatatcac ttctaaatct ttaggctcaa
     8821 atacaccaat caacgttgtt cgcgcaacag ttgaaggttt gaaacaattg aaacgtgcag
     8881 aagaagttgc agaacttcgc ggcaaatcag ttgaagaatt aatcggataa ggaggacaac
     8941 aataatggct gaattaaaag ttactttaaa acgcagtatt atcggacgtc ctcaaaacca
     9001 acgcgataca gttaaagcgt taggtcttac aaagattaac agttcagtgg ttaagccttc
     9061 taatgaagca attaaaggca tgatcaatac tgtttctcac ctagtggacg ttgaagaaat
     9121 ttaatttaga aaaatcataa ctagaacatt aaggaggtgc caaacctatg aaacttcatg
     9181 aattaaaacc tgctgaaggt tcacgccaag tacgtaaccg tgttggtcgt ggtacttcat
     9241 ctggtaacgg aaaaactgcc ggacgcggac aaaaaggaca aaaagctcgt tcaggcggcg
     9301 gtgtgcgttt aggatttgaa gggggacaaa caccattgtt ccgtcgttta ccaaaacgag
     9361 gattcacaaa cgtgaaccgt aaagactatg cagtcattaa tcttgatgta ttgaaccgct
     9421 ttgaagacgg agctgaagta actcctgttg ctttagttga agctggaatc gtgaaaaacg
     9481 aaaaagctgg aatcaaagta ttagctaatg gggaactaaa caagaaatta actgtgaaag
     9541 cagcaaaatt ctctaaagca gctcaagaag caattgaagc ggctggtgga tcaatcgagg
     9601 tgatctaatg tttagactat taaaagatgc ttttaaagta aaagacatta gatcgaaaat
     9661 cctatttact gtatttgtgt tgtttgtatt tcgcctaggt gcacatatta ctgtaccagg
     9721 cgtaaatgct gcttcattgc aaaacctttc ttctttgcca tttttcaaca tgttgaactt
     9781 ggtaagtggt agtgcgatgc aaaacttttc cattttctca atgggggttt caccatacat
     9841 tactgcttct atcgtcattc agcttcttca aatggacatc gtgcctcgat ttgttgaatg
     9901 gtcgaaacaa ggggaagttg gtcgtaaaaa actgaatcaa gcgactcgat atctgacatt
     9961 agtattggca tttatccaat ctgtcggtat cactgctgga ttcaatcaat acgctcaatt
    10021 aggtttcgtg aataatccta acgtagcaac ttacgtaacg atcggtttga ttctaacagc
    10081 cggtacgatg tttgttactt ggctaggaga acagatcaca gaaaaaggta tcggaaatgg
    10141 cgtatcaatg atcatttttg caggtatcat ttctagattg cctgaaagta tcagagaaat
    10201 ttatgaagat tactttataa atattgatcc ttcagacata tggaaatctg ctatttttgt
    10261 ggccatttta ctagtagcgg tcttgttgat cgtgacattc gtaacatttt tccaacaagc
    10321 tgaacgcaag atcccgatcc aatatacgaa acgcgtagct ggcgcgccta caagcagcta
    10381 tctgccgttg aaagtaaatg cagctggagt tattccagtt atctttgcta gttcgtttat
    10441 tgctacgcca aatgctgttt tacaagcatt gagcggtaga ttcggttctg aaaactggta
    10501 caaagtgatg atggagatct ttaactataa tacagcacct ggtgctacga tttatacgat
    10561 tctgatcgtt gccttcactt tcttctacgc ctttgttcaa gtaaaccctg agaaattagc
    10621 ggaaaacttg caaaagcaag gaagttatat accaagcgta cgccctggta aggggactga
    10681 agagtatgtc tcaagattac tgatgcgttt aagtacagtt ggtgcagtct tccttggttt
    10741 agtggcattg cttccaatca ttgctcaaat ggtttgggat cttccacaat caatcggatt
    10801 aggcggtaca agcttactga tcgttatcgg tgtagcttta gaaactgcga aacagttaga
    10861 aggcttaatg ctgaaacgta aatatgttgg attcattgag taagaaagcg tgttgaggtt
    10921 tcccctcaac acacgttctc acacatttat taggagggaa aacaatgaac ctcattttaa
    10981 tggggctgcc aggcgcaggt aaaggaacac aagctgaaaa aatcattgat gcttatggta
    11041 ttccgcacat ctcaacagga gatatgttcc gcgcagcgat gcaaaacgaa acagctcttg
    11101 gcctggaagc aaagtcttat atggataaag gtgcattagt tcctgatgaa gtaacaaatg
    11161 gaatcgtgaa agagcgacta gctgaaccag atacagagaa aggcttctta ttagatggct
    11221 ttccacgtac gctagatcaa gcaaaagctc tggacgcaat gctaaaagat ttgaataaaa
    11281 aaattgatgc tgtcatcgat atccatgttg gtgaagaaat cttggtcgaa cgtctagccg
    11341 gccgatttat ctgcagcaat tgtggagcaa cttaccataa aattttcaac cctacaaaag
    11401 ttgaagacac atgtgatcgt tgcggtgggc atgaattcta tcaaagagaa gatgataaac
    11461 ctgagacggt taaaaatcgt ctggctatca acatcaaaaa tagtgaacca atcttggctt
    11521 attataaaga acaaggtttg ctaaacacta ttgatggtgc tcgtgaaatc gatgctgtat
    11581 ttgcagatgt acaaaaaatc attgaaaaat agcacgattg cccgtagccg acttgcatta
    11641 tgcagttact cttgtcaagt tcaataaatt atgatagaat atgtcagtcc gacttctaga
    11701 gaatcctcta gatgatccat tttgagaatt ttgaggtggg aactgcagtt tccgccattt
    11761 tatcgtgtga aaatgcgaaa caagtacaag gaggtactgt gcgtggcaaa agaagatatg
    11821 attgaagtcg aaggtacagt cgtcgaaact ttgccgaatg caatgtttaa agttgaacta
    11881 gaaaacggac accaagttct tgctactgtt tcaggtaaaa ttcgtatgca ttacatccgt
    11941 atcttacctg gtgacaaagt aacggttgaa ttgtctccat acgatcttaa ccgtggccgt
    12001 attacttatc gctttaaata attgtactcc gtaaaactac aggaggtatt atcatgaaag
    12061 taagaccatc agtaaaacca atgtgcgaac attgtaaagt aattcgtcgt aaaggacgcg
    12121 ttatggtgat ttgcccagca aatccaaaac ataaacaacg tcaaggataa ttggaggtgc
    12181 tataaatatg gctcgtattg caggagtaga tattcctcgt gataaacgtg tagtagtttc
    12241 acttacttat atctatggta ttggtaacac tactgctaaa aagatcttag ctgatgctgg
    12301 tgtatctgaa gatgttcgcg ttcgtgaatt aacgaatgaa caaacagatg ctatccgtgc
    12361 agaagtagat aaattaaaag ttgaagggga tcttcgtcgt gaagtgaact tgaacatcaa
    12421 acgtttgatg gaaatcggtt cttaccgtgg aatccgtcat cgccgtggat tgcctgttcg
    12481 tggacaaaac acgaaaaaca atgcacgtac tcgtaaaggc ccagctcgcg ctatcgctgg
    12541 caagaaaaaa taattcttaa gtgaaggagg ttaaaacttc atggcagcaa aaaaagtgaa
    12601 tcgtaaacgc cgtgtgaaga agaatataga agcaggtatt gcacatatcc attctacatt
    12661 caataacact atcatcatga tcactgatac tcacggaaat gcattagcgt ggtcatcagc
    12721 tggttcatta ggtttcaaag gaagcaaaaa atcaactcct tttgccgctc aaatggcagc
    12781 agaaactgct acaaaagcag caatggaaca cggattaaag actgttgaag taacagttaa
    12841 aggacctggt tctggacgtg aagcagcaat tcgttcatta caagctacag gtttagaagt
    12901 gactgcaatt cgtgacgtga ctccagttcc tcataatggt gcccgccctc caaaacgccg
    12961 tcgtgtttaa tgagtgccgc tcattttgag ttttatcagt aacgtcattg aacaagacac
    13021 ttttcgtttt gaaaggggta aagataagaa tgattgagtt cgaaaaacca agaatcgcaa
    13081 aaattgatga agaaaaagat tatggcaagt tcatcgttga acctcttgaa agagggtatg
    13141 ggactacttt agggaattcc ctacgtcgta ttttattatc ttctttgcca ggtgctgcca
    13201 tcactaatat tcaaatcgat ggtgtactgc atgaattctc taccatcaaa ggtgttagag
    13261 aagacgtcac tcaaatcatc ttgaacatta aaggcttagc gctgaaaatg tatggccaag
    13321 aagaaaaaac ccttgaaatc gatattaccg gacctgctac agtaactgct ggcgatatta
    13381 tcgttgatag tgatgtagaa attcttaaca aagatatgta catctgtagt gtctctgaag
    13441 gagctacgtt ccatgctcgc ttaacagtga aacctggacg tggttatgtt caagcagatg
    13501 aaaataaaaa agaagatatg ccaattggcg ttcttccagt cgattcaatc tacacacctg
    13561 ttcgtcgtgt gaactatcaa gttgagaaca cacgtgttgg acaccgtgaa gattttgata
    13621 aattgacgat ggagatttgg acagatggtt caattgaacc gttggaagca atgagtttgt
    13681 ctgcgaaaat catgactgaa catttggata tttttgtgaa cttaactgat gaagcaaaaa
    13741 atgctgaaat catggtcgaa aaagaagaaa cacaaaaaga aaaaatgttg gaaatgacga
    13801 tcgaagagtt agacttgtct gttcgctctt acaattgttt gaaacgtgca ggaatcaata
    13861 ctgtacaaga acttacaaat aaatctgagc ctgaaatgat caaagtccgt aacttaggac
    13921 gtaaatcatt agaagaagtt aaagcaaaat tgcacgactt aggtttaggt ttacgtaaag
    13981 aagattaaaa ccttttacga aggagggaaa ccaacgtgag ttatcgtaaa ctaggacgca
    14041 catctagcca acgtaaagcg atgttgcgtg atttaacaac tgatttatta atcaacgaac
    14101 gtattgtgac tactgaagct cgtgcgaaag aagttcgctc aactgcagaa aaaatgatca
    14161 ctttaggtaa acgcggagat ttgcatgcac gtcgtcaagc tgcggctttc gtacgtaatg
    14221 aagttgccag cgtgcgtgaa gaaaatgagg acatcgtcat tgaatcagct ttacaaaaac
    14281 tgttcaacga tattgcacct cgttacgcag aacgtcaagg cggatacaca cgcattttga
    14341 agacagaacc aagacgcggt gatggtgcac caatggttgt cttagaactt gtctaaaatc
    14401 acactaataa catcacttta tagatgattc ttttagagtg ttatgatgtt ggaagatatt
    14461 tttccgagtc tagctcagcg ctgctcctca agcgaatatc gcttggggag taagcactca
    14521 tcataaagtg tttttttata ccttcaatta cctgtcatga cagatatgtt tgaaggcata
    14581 aaaaaacatt ttaagcgaga aataattgaa aattttgtct ttttttgata gtgttagtag
    14641 gaactttagg atgaagaagg agtaatcatg gagccaatta ttgaattaga aaagataaat
    14701 tataaatacc agccagatga tcttcgcccc gcattgaaag atgtctcctt tacaattgat
    14761 aaaggtgagt ggatcgctat tattggacac aatggttcag gaaaatcgac acttgccaaa
    14821 acgatcaatg gattgcttct gccagaatca gggatcgtga aagtgggaaa tcaaatattg
    14881 gatgaagaaa atatttggac gatccgacag atggttggaa tggtttttca aaatccagac
    14941 aatcagtttg ttggttcgac agtagaagat gacgttgctt ttggtcttga aaatcaaggg
    15001 attcccagag aagaaatgct agtgcgtgtg aaagatgcac ttgagaaagt tagaatggct
    15061 gagtttgctt cacgcgagcc tgctcgttta tcaggagggc aaaaacaacg tgttgccatt
    15121 gccggcgtgg ttgccttacg acctgatatc attattttag atgaagcaac cagtatgcta
    15181 gatccagaag gtcgtgaaga agtgatctct acgatcaaga agatcaaaga agaaagtcaa
    15241 ttgaccgtta tatctatcac tcatgatatt gatgaagcag ctaatgccaa tcggatacta
    15301 gtgatgagac aaggcgaact tgtccgtgaa ggtacaccaa aagaaatttt ttctgctggt
    15361 cctgaactga tcgacttagg tctagatcta ccatttcctg aaaaactgaa gagcgcactg
    15421 aaagaacgtg gggttgatgt gcccagtgaa tatatgacag aagaaaggat ggtggattgg
    15481 ttatggacat ccgttttgaa caagtagact tcacttatca gccgaataca ccatttgaac
    15541 aaagagcctt atttgacatc aatatgacga tcaaagaaaa cagttatact gcattagtag
    15601 ggcataccgg aagcgggaaa tcaaccttac ttcagcattt gaatgcgctt gttaagccaa
    15661 caagcggtac agtccatatt ggagaacgag atattcagcc ggatacggat aataagaatt
    15721 taaagcccat ccgaaaaaaa gttggcatcg tctttcagtt tccagaagca cagctattcg
    15781 aagaaacggt agcaaaagac attgctttcg gtcctaaaaa ctttggtgtc agcgaagaag
    15841 aagcactagt cctagcaaaa gaaacattag aacaagttgg gctggatgaa agctatttgg
    15901 aacgttcgcc atttgaactt tcaggagggc aaatgcgtag agtagcaatc gctggtgtgc
    15961 ttgccatgag gccggaagta cttgtattgg atgaaccaac ggcaggactt gatccccagg
    16021 gcagaaaaga aatgatggag atgttttggc gtcttcataa ggaacagcag atcactattg
    16081 tattagttac gcatttaatg gatgatgtag ccaattttgc agattatgtc tatgtgttgg
    16141 aaaagggacg aatcgttaat agcggggagc cgcaagaggt ctttcaaaac attgaatggc
    16201 taaaagaaaa acaactaggc gtacctactg ccaccgagtt tgcagaagaa ttaatggcta
    16261 aagggatgaa ctttgctacc ttgcctttga cagctgatga attagcagac gctatcgtcc
    16321 attatgctgg aggaaatgcc catgatgaat aaattgatat ttggtcgtta tatgcctgga
    16381 gattccttga tccatcgatt ggatccccga gctaaattat tagccagttt ttattttatc
    16441 ggaatcattt ttttagcaaa taattgggaa acgtaccttt tgttggcatt tttcacatta
    16501 ctttctgtct tcttgtcaaa agtagatttg aaatttttta tccgaggcat tcgcccattg
    16561 atctggctaa tcctcttcac tgtagctttg caggtcttgt ttacaagtgg cggagaaact
    16621 tattggagtt ggggtgtttt ccatatcact gaatttggtg tgatgaacgg cctctttatt
    16681 ttctgtcgat tcgtgttgat catttttatg tcgactctac tcacgcttac tacaccgcct
    16741 ttggaattat cggatgcgat tgagtacttg cttcgtccat tgaaagccgt acggttccca
    16801 gtccacgaaa tttcattgat gctgtcgatt gctcttcgtt ttgtgcctac attgatggac
    16861 gaaacagaaa agatcatgaa cgctcagcgc gctcgcggtg ttgattttgg tgaaggaaac
    16921 ctagttcaga aaatgaaagc agtcattcct ttgctgattc ctttatttgt cagcagcttc
    16981 aaccgtgcgg aagatcttgc gactgctatg gaagcaagag gctacaaagg tggggaagga
    17041 agaacgaaat atcgtgtatt gcattggcat aatagagaca cgatggttat cattgctttt
    17101 gtattattaa ctgtgctact gatcttttta agaggataaa cgttcagtgg gccgctatct
    17161 attcttttct tgctgatctg tttgcaagaa aggatgcaag cagtgtatga caagaaatat
    17221 tagggtctgt ggcagactaa ggtcacaggc ctctttcttt tatctgaaaa gaaagaacga
    17281 aaaaatttta tagaaaaatc attattccag ataacctttt aggaacaaag gagagaaaaa
    17341 catggtacgt tacaaagcaa tcattgcgta cgacggaaca aattttaatg gattccaaaa
    17401 acagccaaat gggcgtactg ttcaagaaga agtagaaaaa acattacaaa aaatggcaaa
    17461 tggaaaagaa atcacggtct ttggttcggg aaggacagat gccggagtac atgcgatcgg
    17521 gcaagtaatc cattttgatt atccagagga gcgtccgtta gaacgaatgc gtttcgcgct
    17581 agatacccag tcaccagagg atattgctgt aagacaagta gaaattgttt cagaagactt
    17641 ccacgcaaga tatttggtca aagaaaagac gtatcaattt cgagtggata tagggaaacc
    17701 acgcagtcct tttcgacgcc attatgcaag ttattttcct tacccacttg atttggaaaa
    17761 aattcagcgg gcgcttcctg atttattagg gactcacgat ttcacctctt tttgtgcatc
    17821 aggaagctcg atagaggata aaatacgtac gatctacgag gctaagatgg aggtaaatga
    17881 aacaaaagac gaattgttgt ttacatttag gggaaatggc ttcttgtata agatgatacg
    17941 gatcttagta ggaacgcttt tgaaaattgg caatggccga ttgcctgaag atagtatccc
    18001 agatattatt gcgaaaaaag atcgtaatgc agcaggacct acagcacacc ctgaaggact
    18061 ttatttgtat gaagtgaaat atgaataaga ggttatgata gaagtggtca gcttcaagaa
    18121 ataagaaggt atttacgaaa attacttctc aaaattttgc aaaatttcgg cttattttcg
    18181 aagaagctac ttctggaaca ccgtttaaga aagaggtcgt gagcctgtca tttaactctg
    18241 agtcacaaag agcaatttca aaaaacagct tctcatcttt gatgaatatc gtgacttgtg
    18301 gacgaggcgt tgataagtga atcatctttt tgttacctat tttttctgta accaaaaaac
    18361 gatggaacgt tgttttgatt gcccttggtg cggacagtct gaacaggttc catcgtttct
    18421 ttattttcta cgtcttcttc tgtgtgtgtt tcgtggttgt tcttctattg ctggatcaat
    18481 cgtgccataa aaggggcgat tgcggtcaag gtaccagaca taaagaataa acaatgcaat
    18541 acataggaca aaaaggattg cacctatcgt aaatccttca ggcaagtaac tgaaagtgac
    18601 agtatgttta cctgctggaa cttttatcat caagaatgcg tctttgaaat tgctgacctt
    18661 gactggtttc ccatcaattt tagctttcca tcctttgtca taaggaatag ttgtcaccaa
    18721 catggaatct tcagcggtat ttacagtccc agaagctttt ctgccagtgg cttccatttc
    18781 gacacctttt tctttgatct gattcattgc ggcttgatag gctacaacat ctagaccaac
    18841 gactttaggc tccatgaaac ttatttcttt cgtcccataa aaacttgcag taaatgtcac
    18901 tgttgtctct tgaggataat agccaagatc atagtattga ccagaaatgt tgatttgcgt
    18961 ttttcgcgat gtaccattga cagtgatcgt cgcactagaa ctttctaatt gcgcaaaatt
    19021 ggttgggaac aaacttaagt aagcttgtgt atttgcaggc acatggactt cccaagtgag
    19081 ctcttttggc tggttatctg ctgtttctga gtaagtgacg ccagtcgttg tctttgtgat
    19141 cgtcgtattc aactgattct tcaaagtagg tgtatagaat gtaaaatact gttcatttag
    19201 accagacaat gtattgatca agtttgtctg actggtcaaa ttatctgtca ctggctgctc
    19261 aacatcatta acggacaacg gtgcagtaaa tgctagtggc aatgcattga cattctgata
    19321 cagtgtatag tcgccgcttt gaccagcttg gcggaagcca tatttactga acgtgctttc
    19381 gtttttagaa atgttatatt tgattcctgt aaacccatcc atcagcaaag tattattgtt
    19441 ataacggata ttcaaatttg tccctcttga acggaaacct aatttatcca ggtaagagga
    19501 agaattacga tttcttatag aagaaaacaa actgatacca ctgtaaccat agttgatcga
    19561 atcgtttgca gatactggat ccagattttc caagcggtaa aacgagtcgg aatctttttt
    19621 tgtttcattt acaagagctt tcaagtcagg ataaggatca gtatataaac tgcgggaagc
    19681 ataattccaa tcatcaagaa tgccatggat catactgttc gtattgacca gtgcttcagc
    19741 agacatgatc aataataaca atatactcag atgattgaat gaaagttttt tatgctgata
    19801 aaatcccaca gcaaaagcat aaatccctaa gaaaaccact gtcaatacaa aggaagtcat
    19861 cgtcacatag gtgtagcttc cttcaggttt gatgccccat gccaccgcaa agagagcagc
    19921 tacgaccaaa atgattccta acaacagccc acgatcgtct tgttctatct tttcccatcc
    19981 ttttcctgca agcaggagca ctaagaaaga gaacagatag gcataacgga ataaaaacat
    20041 attcggtgca tgcataccat gccagaacaa attcaatgga acaagataaa aacttgcgat
    20101 aagtatggcg aaaagactgc cgtacaaaaa tttatttttc aacggtactt tccgactggc
    20161 aaaataaaac agacagagga ctaatggtag cagacctgcg taaacgaacg gaatcgatcc
    20221 gtattttgtc gtgtcataaa caccaatcat atttttcatg attagatcca gataagaagt
    20281 cgcttctgtt ttcaacgtag tgatctgact cagtgcctcg ccatttgacc gaagatccag
    20341 cactgctggc aatacaatga tcattgaagc gccgcctgcc agtaaagaag tgataccata
    20401 aggaacaatc gtttttttat attctgacca gtttgtcaat agacgggcga taaaatataa
    20461 gaaagaaaat acgccaatca taaaacccat ataaaaactg gataaaaaca agagtaaata
    20521 actgataaat aaaagtttcg gccgtttaag atccataaca cgatgaatcc ccaaaatcac
    20581 taatggaaga taaacaaatg catccagcca catgatgatc tccgaatgtg cagtgataaa
    20641 tgagatcaat gcgtaactga cgctaagtgc aacatgcccc cagcgaggaa tcttgaacgt
    20701 acgtgcaaga aaccaaaaag ccaatccggc acagccgacc ttaagcaaag tcagaacata
    20761 cagtgcatct ggcatcatct ggtttggaaa aaagaacacc agtggcgtga agatcccgcc
    20821 tagatagtaa gaaattaaag ataaataatt caatcctaga gaagcattcc atgtataaaa
    20881 aatactttgc tttccaagaa gaacatttcg gaagctggca tgaaaattag aaaactgtga
    20941 aaaggcatca cttgccaaaa tacttctgct gcttccagga tagattccga tacttagata
    21001 aacaagtgct aaaatcaaaa acggaatcag gaaactagct gctgcgtagc gtccgttttc
    21061 tctaaagaat gactttaaat tttttttcat atttattttc caccaaattt ctatgaagtt
    21121 gtattcagtt tatcatatcc ttgtttttct ctgcttaaaa agagtctagt tttcacaaaa
    21181 aaataaaatt tagaataaat aacttcataa tttgttcgta taacaaaaat aaacgcaaaa
    21241 aaagggtagg aatcaaaagt cccaccctta aaaattttta ttaaataaaa aaccgttcac
    21301 tatctgaacg gtccaagtat cattcaatta aacgcgttca acttttcctg atttcaaagc
    21361 acgagttgac acccaaactt ttttaggttt tccgtcgacc ataacgcgaa ctttttgtaa
    21421 gttaggttta acagtacgtt ttgttgagtt catagcgtgt gaacggttgt ttccactttt
    21481 tgtcttgcga cctgtaaagt aacaaacttt tgccatggta atttcctcct ttgccttgat
    21541 ttggagcaat agaataattc agctcatacc agactaacat atcatataga atgggaattt
    21601 gcaagtacat tttcatagat acaattgaca attgagaaga ataattgtaa attaaacaag
    21661 gttatacctg aaattttgca aggtttttga gtactttggg taactgcctt ttatttcaag
    21721 ttgcgctatg ataaaatatg atagaagaaa aatgggagtt ttttacccgt taaggaggct
    21781 cattcatggc tgtaaaaatt caaacgtcag ctggaaccat tgaaattacc aatgatgtaa
    21841 ttgcaacagt tgttggtggc gccgcgacag atgtgttcgg tgttgtagga atggccagca
    21901 aaaatcaaat taaagataat attactgaga ttttgcgtaa agaaaattac tcaagaggag
    21961 tagttgtccg ccaagaagat aatggtattg ctgtagatgt ttatacgatt atcagctatg
    22021 gtacgaaaat ctctgaagtt tcccgcaacg tccaagaaaa agtgaaatac aatctagagg
    22081 cattattagg cgtaactgcc aattcagtta atgtctttgt acaaggtgtt cgtgtactgc
    22141 cagactaggc aggagactgg ctggtaactc agcagtcgat ctgaaggagg attatctagg
    22201 tgagtgtaac agaaataagt gcaagccagt tccaggaaat ggtccaggca ggtgcgaatc
    22261 gtctgcaagt aaatgcagaa tacgtcaatt cattaaatgt attccctgtg ccagatggcg
    22321 atacgggaac aaatatgaat ctatctatga ctagtggagc taaggcagta gtagattcaa
    22381 cctcagaaaa agtaggagaa ttagcagcaa tgctttcaaa aggattgctg atgggtgcgc
    22441 gcggaaattc cggcgttatt ttgtctcaat tgtttcgtgg attttctaag caaattccag
    22501 atgttgtctc attaaatgct tctgatcttg ctgcagcctt cactcatgga gttgaaactg
    22561 cgtataaagc agtaatgaaa ccagtagaag gaacgatttt gacagtagct agagaagcag
    22621 cgaaagctgg agaaaagaaa gcaaaaagta ctgatgatgt cgttgaagta atgacagctg
    22681 ttgtaaaagg agcaaagcgt gctttagcta aaactccaga cttgcttcca gtcctaaaag
    22741 aagtcggtgt cgtagacagt ggagggcaag gactgctgtt tgtttatgag ggctttttaa
    22801 gtgcattgaa tggagaattc caagcggatg aaacatatga accttctcca gcagaaatgg
    22861 atgatatggt caatgcagaa catcatcgca gtgtccaagg tcaaatggcg acagaagata
    22921 tccattttgg ttactgtaca gaaatcatgg taaaaatcgg agaaggacct acagtcgata
    22981 gtacattcga ttacgaagaa ttccgtaact atttagatgg tataggagat tctttacttg
    23041 tggtcaatga tgacgagatc atcaaagtcc acgtgcatac agaaaaccca ggagaagtct
    23101 tgaattatgg acaaaaattc ggttcattag tcaaaatcaa agtcgacaac atgcgcttgc
    23161 agcatgagac gattttggaa cacgatgaag aagtgaacga gtttgcgaaa aaagaaatac
    23221 cacgtatccc gtatggtatc gtagcgatcg ctgctggtaa aggcgtccaa gagctgtttg
    23281 aaagtttagg cgctaattat gttatcagtg gtggacaaac aatgaatcca agtacggaag
    23341 acattgttaa agcgattcaa gaagtaaacg cagataaagt gattgtcttg ccaaacaata
    23401 agaacatctt catggcagct gatcaagcag cagaagtagc agatatccca gtagcagttg
    23461 ttccttcaag aacgatttcc caaggattga cagctatgct ttcattcaat gatcaagctt
    23521 ctttagaaga aaacaaagaa acgatgacag aaatgttgtc tagcgttgtg agcggtcaag
    23581 tcactcacgc gatcagagat acctcaattg acggtgtaga gatcaaagaa ggagactttt
    23641 tgggcatgat cgatggaaaa atcctgatct ctaacccaga tatcacagca acagcgttaa
    23701 gtacactaga acaaatgatc aatgaggaca cagagatcgt aacgatcttg gcaggtgatg
    23761 aaggaacagt tgaacaagca aatgaatttg ctgagaaact aacagaaaaa catcctgatt
    23821 tggaaatcga gatccaccaa ggagatcagc ctgtctatcc ttatctattt tctgctgaat
    23881 aatttctgtg tcagaatatc tttctaacac agtattcatt cataaaaggc cttcggttag
    23941 tgatcaggta tgatcgctga ccaagtcctt tttttgttaa aggagggagg aaaaatttat
    24001 gcgttcttta gatgatccaa tcactatgct ggcaggagtc ggagaaaaaa gagcagctag
    24061 tcttgccagc ttgggcatcc aaacgattga agacttactg acttattatc cttttcgcta
    24121 cgaagatatt caggaaagaa atctaaacga gatccaggat caagaaaagg ttactttgaa
    24181 aggaatcgta gtctcgcctc ctgtgatgaa tcgatttggt tataaaaaaa gccgattgca
    24241 atttcgtatg atgcaagaac atgatgtgtt caacgtttct ttttttaatc aaccttatct
    24301 aaaagaaaaa gtcattttat cggaggaaat cgccgtatac ggtaaatggg atgcaaagcg
    24361 taaagccttg aacgggatga agattttagg ttctcaaaca atggatgact tttcgccgat
    24421 atatcacgtc aacaaatcaa ttcgtcaaac gacattagtt gatctaatca aaaaagggtt
    24481 tcaagaatac ggcacattga ttgaagaaaa tctgccaaac aaccttgtgg agaaatatcg
    24541 actgcttgac cgagcttctg ctgtaagaag tatgcatttt ccaaaagacc acgaagaaaa
    24601 ccatcaagcc aaacgacgtg tcgtttttga agagttcttt ttatttcaaa tgcgtcttca
    24661 aggattgaaa aaagcagaaa aagcagaaac gaatggtttg gagatccttt atgatgtcca
    24721 aaaattgaaa caatttactc aaaagctacc ttttgaactg acaaatgcac aaaaacgtgt
    24781 aacgaatgaa atctgtcggg atcttcgcag tccgcagcat atgcagcgac ttttgcaggg
    24841 agatgtaggt agcggaaaaa cagtggttgc cgcgattgcg ttatacgcta ccgttacagc
    24901 aggtttccaa ggtgcgttga tggtgcctac agaaatcttg gcacaacaac atatggaaag
    24961 cttgcaacag ctgtttgatc ccaatgaagt aaccatcgca ttgattacgg ggtcaacgaa
    25021 agcaaaagaa cgacgtgagc tccttgaaaa actagagcaa ggggaaatta acgtcgtgat
    25081 cggcacacat gcattgatcc aagatggagt cgaatttcag aatttaggtc tagttattac
    25141 ggatgagcag caccgttttg gcgtgaacca gcggaaagta cttcgtgaaa aaggctggcg
    25201 accagatgtc ttatttatga cagcgactcc gattcctaga acattagcta ttacagcata
    25261 tggtgagatg gatgtatcta tcattgatga acttccagct ggacgtatcc cgatcgaaac
    25321 acgctgggta agaacacctc aattggacag tgtactggat tggacgaaaa aagaactggc
    25381 aagaggacat caaatgtatg tcatctgtcc gctgattgaa gaatcagaag cattagatgt
    25441 aaaaaatgca gtggaaatct atgaaaaact tcgtgaacta tttgcaccaa aatatgaagt
    25501 tggcttgtta catggtaaaa tgaagaatca ggaaaaagaa gtaatcatgg aagccttcaa
    25561 agacaaccag atgcagatat tagtttcgac tactgtaatt gaagtagggg taaacgtgcc
    25621 gaacgcgacc gtcatgctga tcatggatgc ggatcgattt ggattggcac agctgcacca
    25681 acttcgtgga cgtgttggac gcggaagtga tgcttcctac tgtatcttag ttgctaatcc
    25741 taaaaatgaa ctaggtgtgg aacggatgaa aatcatgaca gagaccacca atggttttgt
    25801 actaagcgaa aaagatctgg aattacgtgg tcctggtgaa gtatttggct tccgtcaatc
    25861 tggtctgcct caatttgcga ttgctgactt ggtgacggat ggaaatgttt tggaggtagc
    25921 cagagaagag gctgcagccc tttggcaaat aaaggattgg cagatgcttc ctgagtatca
    25981 gcctttagcg caaagcctcc aaatagaaaa tcaggataat cgttatttcg attagcagac
    26041 tgtgctatac tttatactga tgacggaaaa aggagtggaa acaatgaaaa ttgccgtaga
    26101 tgcaatgggc ggagatcacg cacctcaagc aattgtagaa ggcgtggctt tagcgcagca
    26161 agattttcca gaagtagaat tcttacttta cggaaaagaa gcagaaatca agaaatactt
    26221 aacaaatgaa aaaaacatca cgattatcca tacagacgaa aaaatcaata gtgatgatga
    26281 gccagtaaaa gcaattcgac gaaaaaagac tgcatcaatg gtccttgctg cacaagcagt
    26341 gaaaaacggt gaagcagatg ctgtattttc agcagggaat acaggcgcgc tactagcagc
    26401 agggttgttc atcgtaggac gtatcaaaaa tatcgaacgc cctggcttga tgtctacctt
    26461 gccagtagta gggaaagaag gtgccggttt cgatatgctg gatcttggcg ctaacgcaga
    26521 aaacaaacca gaacatttgt tgcaatacgg tattttaggt tctttttatg cacgtaaagt
    26581 ccgaggtatc ggacgtcctc gtgtcgcact cttaaacaac ggaacagaag caacaaaagg
    26641 tagtgaagtg acgaaaaaag cctatgaact ccttcagaat gaaacaagct tgaattttat
    26701 tggaaacgta gaagctcgtg agctactcaa tggtgtggct gatgtagtgg tcacagatgg
    26761 atttacaggc aacgctgttt tgaaatctat tgaaggaaca gcaatgaata tgatgaatct
    26821 attaaaatct gctattctaa atgaagggat caaaggaaaa atgggcgcta tgcttttaaa
    26881 agacggctta cgttctttga aagcagaaat ggattattcc aaacatggcg gtgccgtttt
    26941 gtttggcttg aaagcaccag tcattaaaac tcatggagca acaggccccg atgctgttcg
    27001 ctatacgatc cgccaaatcc acacaatgct tgagacagat gtagttggac aattagtcga
    27061 acaatttgaa aaaagcgaag aatagtattt ggatatctga agcgatccgt tccattgaaa
    27121 aaaaggtgga cattcctgaa aaatgccagt aaaattagcc atggtgtagg taattgacaa
    27181 gtgtatgatt cttggaggtg aaaaagttga ctcgcgaaga agtatttaac aaagtagcga
    27241 aaattatttc aaatcatttt gagatagata ccgataaagt gacggatgaa ttgaacatca
    27301 aagatgattt aaaagctgat tcaattagta ttatggaatt cgttttagag cttgaagatg
    27361 aattcggtac ggaaatttca gatgaagacg ctgaacaaat tgaaacagtc ggtggcgcag
    27421 tagattatat cagcagccat cttaaataat ttcaaataaa agcaaagaag gataaaaagc
    27481 tgcatgcagc tttttatcct tcttttttta atctttttga cacgtaaaag tcatttttct
    27541 gataattctg gcgataaaca gaaattatgt tgcaaagtaa agcggttttc tatataatta
    27601 ttaataattc attacacaaa gataagaata acctttgtta taaaacgatt tattctgtgt
    27661 aatgtccttt tttattaaga aaaacttcca tttaggaagc agagaggggt attcgattgt
    27721 ccgataacca attattagaa gttcagaacc tacatacagg attccgactc aaagatgact
    27781 attacgatgc agtagatgac gtttcattta ctttagacaa aaacgagatt ttagcaatcg
    27841 ttggggaatc tgggtgcggg aaaagtacct tggctactac gattatggga ttacttgatc
    27901 ctaataacac aaaaattaca ggtgagattt tatataacga tctgaattta atcgacctga
    27961 acgaaacgct ctataataaa atccgcggaa atgatatcgg aatgattttc caagatccgt
    28021 tgtctgcatt aaatcctctc atgagaatcg aagaccagat caaagaagga ctttcctatc
    28081 acacaaagat gaatgcagaa cagcgtcaag ctcgtgcact agaattgcta gaacaagtag
    28141 ggattcctaa tcctgcgaga gttggacgcc aatatcccca tgaactatca ggcggtatga
    28201 gacaacgtgt catcatcgca atcgcaatcg cctgcaaacc tccaatcgtc attgcagatg
    28261 aaccgacgac agccctagat gtaaccatcc aagcacagat tcttgattta ctgaaagacc
    28321 ttcaggaaga aacaaaaaca gggatcatct tgatcactca tgacttagga gtcgtagcag
    28381 aaatggctga tcgagtggca gtgatgtatg gcggacagtt cgttgaagta gcaggtgtaa
    28441 aagaactgtt tgatcatcct aagcatcctt atacacgctc tttactgaac tctataccac
    28501 aagaaggaaa tcatgatgca gaactccatg tgatcgaagg tgtcgttcct tctctgaaaa
    28561 acatgcctcg taaaggttgt cggtttgcac cacgtattcc atggatacca gcaagcgatc
    28621 atgaagaaga gcctatcctt catgaagtcg caccgaacca cttggtacgt tgctcctgct
    28681 ataagcattt ccactttaga gacgaaaaag gagaggtgta gatgacagaa ttaatcacaa
    28741 tcaaagacct gaaagttcat taccctattc gcagtggatt cttcaatcga gtaacggatc
    28801 atgtatatgc tgtagatggt gtggatttta ttatcgaaaa aggaaagaca tatggtttag
    28861 tgggagagtc tggctctgga aaatctacta cgggaaaagc cgttgtggga ttagaaaagg
    28921 taacagccgg acaaatcatg tatgaaggaa aagatgtaac gaagcgaagc aaccgcaaaa
    28981 aaatgggtta taacaaggat gtgcagatga tcttccaaga ttcaatgtcc agtttgaatc
    29041 ctaaaaagcg agtgttggat atcattgctg aacccatccg aaattttgaa cggttaagcg
    29101 atcaagaaga aaagaaaaag gtaaaaggac tgctagatat cgttgggatg ccggaagatg
    29161 cgctatataa atatcctcat gaattttcag gcggacaacg tcaacgtcta ggagtagccc
    29221 gtgctgttgc taccaatcca aaactgatcg tagccgatga acctgtatct gctctggatc
    29281 tatctgttca agcgcaagta ttgaatttca tgaaacgaat ccagcaagaa tacggcctca
    29341 gctatttatt catttcacat gatttaggtg tagtaaaaca catgtgcgac aatatcgcaa
    29401 ttatgtacaa aggtcgattt gtagaaatcg gtacaagaga agacatttat aatgacccgc
    29461 gacatatcta tacgaaacgt ctgctttcag ctattccgca aatcgatgta gaaaataggg
    29521 aaagccacaa agaaaatcga cgaagagtag aacaagagta tatccaaaac caaaaagaat
    29581 actatgatgc gactggtcga gtctacgatt tgcgtacgat cacaactaca cacaaagtgg
    29641 cgttgaaaga tggaggtgca agctaatgtg gaaaacgatt ctgcgacgtg ttttattgat
    29701 gatcccgcaa gttattattt taagtgttct gatcttctta ttagcccaag cgatgccggg
    29761 ggatccattt accggtttga tcaatccaaa tcaggatccg gcagtgatcg aacagatgcg
    29821 acaagcagct ggcttgaatg acccatggta tgtccagtac ttccgttgga tcggaaatgc
    29881 tttgcaaggc gattttggtc aaagtttctt atacaaacgc tctgttgctg acttgatcgg
    29941 cgaacggatc atcaacactt tatatctatc gatcttgaca gttgtcctta cttatttgat
    30001 tgctgtgcct ctggggatgc ttgctggccg gtatcaaaat tcaatcttgg ataagattgt
    30061 cgtaatctac aacttcttta gttttgctgt tcctttattt atcttcggct tgatcatgct
    30121 atttgttttt ggttatcgtt taggctggtt cccaacaagt ggatcacaaa cactaggttt
    30181 gcaaggtgga tttatcactc aatggataga ccgtttgaaa tatattctgt taccatcaat
    30241 tacccaagca tttttggcga ctgccgtcac aatccaatat ctgcgaagtg aagtaatcga
    30301 ttcgaaatcg ctcgattttg tcagaacagc ccgttccaaa ggggtaccga cgaataaagt
    30361 attcagtcga catattttcc gaaatgcagc gttgccgatg gcttctcaaa tggggtatga
    30421 aatcacttcg ttgattgctg gttctgtagt tatcgaaaag atttttggtt atccgggagt
    30481 cggaaaacta tttattgatt ccatcggcca acgggactat accgtgatca catccttagt
    30541 attgatttta ggaatcgcga cgctagtggg gacattactt tcagatatca tcatgagtat
    30601 cgttgacccg cgtattcgga ttcaataaaa ccaatcagaa aggagaatgg atcgatgagt
    30661 gaaaaaaaca atacagcagt tcaagaaagt attcctccta tggggatacg aatgattgct
    30721 cgagaattta aaaaagataa aattgctatt ttttcattag gtttgctagt ggttttatta
    30781 ttagtgatct ttatcggtgc gatgctgacc gatcaagaca aagtgatgta tgttagtatc
    30841 ttcgacaaat acgctgcacc aggaacagtt tcgacacaag gacaaaagtt cattctggga
    30901 gcagatgaag gcggacgtga tgtattagga caattgatca taggtgctag aaactctgtt
    30961 acgatcggat ttgcgatcac gatccttact tcgatcatcg gggttggatt agggatcatc
    31021 tctggctact acggagggat cattgacaac atcttgatgc ggatcgttga ttttatcatg
    31081 attctaccga tcatgctgat cattatcgtc ttcgtatcga ttatttccag atacaatgtc
    31141 tggtccttta tattcatcat gagtgcattt tattgggtag ctaaagcccg attattccga
    31201 agcaagacat tatctgaagc aagaagagat tatgtcagtg cctcaaaaac aatgggaacc
    31261 aatgatttta aaatcatgtt ccgcgaaatc atgccgaatc taagttcatt aatcattact
    31321 aatttgacga tgaactttgc ggcaaacatc ggtatcgaga caactttgac tttcttaggt
    31381 ttcggcttgc cggcaaatgt acctagttta ggtacattga tcggttatgc aagtaacgga
    31441 gaagtcttag tgaatcggca atggatctgg ttacccgcat caatccttat tttagttttg
    31501 atgttgagta tcaattatgt tggacaagca ttcaagcgtt ctgcagatgc gcgccaacgg
    31561 ttaggctagt atagaagcga agggggaaat aggaatgaag aaaacgattt ttggatttgc
    31621 agcgctgatg tctgctgtcg ttcttgcagc atgcgggggc ggaggtacag atacctctgg
    31681 aaacaactct ggaggcaacg gcaataacaa agaggaatta acttttccaa ttgcaacaaa
    31741 aaataatgat gatgcaatcg aagacggcga attagaagct gcggtcgcaa cggacagtca
    31801 gtttaaagga ttgttccagt gggagtttta ccaagattca tatgatgcag cttttatggc
    31861 tccttctcat gaaccgctat ttgcaaacga tgacgatttc agaatcacag acgacggagc
    31921 tgcaacgctt gatctagatg aagatacgaa aaaagcgaca atcaaagtaa aagacaacgt
    31981 caaatggtca gatggtgaag atgtaacggc ggacgatgtg attttccctt acgaaatcat
    32041 tgggaataaa gattacactg gtatccgtta tgacgacact ttccgtaaca tcgtaggtat
    32101 ggaagaatat catgatggaa gtgccgacac aatctccgga atcaaaaaaa tagacgacaa
    32161 aacagttgaa atcgaatata aagaagtaaa cccaagcatg cttcaatcgg gtggtggtat
    32221 ctggtcatat gcagcaccaa aacatacgtt agaaggtgta gcaatcaaag atatggaatc
    32281 aagcgatcaa gtacgtaaaa atccagtgac ttttggccct tattacatga gtaatatcgt
    32341 tgcaggagaa tcagtagaat acttgccaaa cgagcactac tggaatggta cgcctaaatt
    32401 gaaaaagatc acgatgaaat ctgtaccgat ggcaagtgca actgaagcat tgaactctaa
    32461 attatatgat atgattttcc aaatgccaac agatacttac gatacctata aagaaattgc
    32521 tggctataca aacttaggcc gtgaacaaac ttcttatact tatctaggat tcaagttagg
    32581 taaatggaat gcagatacaa agagtgtgga atacaatcca gattcaaaaa tggctgataa
    32641 atcattacgt caagcaatgg gctatgcatt agataataat gcagtaggtg aacgtttcta
    32701 tgcaggtttg agaagcaatg cgacttcatt gattcctcca gtattccagt cataccatga
    32761 tgatgagatg aaaggattca cacaagatct agacaaagcg aaaaaactat tagatgatgc
    32821 tggctacaaa gatgtggatg acgatggttt aagagaagac aaagatggaa ataaactaac
    32881 aatcaacttt gcttcgatgt ccggtgggga aacagcgcaa ccattggcag attactatat
    32941 ccaacaatgg aaagaaattg gtttggatgt ccaatacaca acaggtcgtc tgatcgaatt
    33001 caattctttc tatgataaat tagaaaacga tgatcctgaa attgatgttt accaagctgc
    33061 ttggaataca ggaactgatc caaatccaag tggactatgg ggaccaaatg ctgcgttcaa
    33121 ctacactcgt tatgaatcag aagaaaatac aaaattgatc aacgatatca gttcaagcaa
    33181 agcatttgat gaagagtacc aaaaagaagc atatcaaaaa tggcaacaat atgcatttga
    33241 agaagcattt gcgattccaa cgttgttccg taatgaagta ttgccagtca acgaccgtgt
    33301 caaagactgg gattggtctt atgatgtacc aaacccatgg gcaaatgttt ctgttacagc
    33361 agattcacgt tcataatcac taaaaatgac cgaaaaaggg cgatgtcctt tttcggtttt
    33421 ttgatatttt tctgtttatt tctctaatat tcaggtcaag gcgctgattt catgacttct
    33481 ccaataaacg gtgttcaaag tccagtttct cggtattaag tcaaatttat gcaaaaatat
    33541 ggaaagccat tttcacaaaa ttttttcttc atactcgaaa ctaaacgaat ttttcacaac
    33601 ttctcgtcaa tcactaggat tattaaagct ttacttacct tttgaccgaa ccatttcaaa
    33661 tttgacaaaa aaccagtata ataaggaagt atcgaaaaaa tatccataaa aggaatgtgg
    33721 aaaatggaca accagctgac aaaagaacta aaagaaaact ataacatcgt ttttcacgat
    33781 ctaaatttgc ttgaacaagc ttttacccat tcatcctatg tgaatgagca tcgcaatctg
    33841 caattatcgg ataatgagcg acttgaattt ttaggagatg ccgttttaga actgatggtt
    33901 tctcagtatt tattccgttt atatcctcat ttgccagaag gaaaattgac aaaaacacga
    33961 gctgcgatcg ttcgcgaaga cagcttgtcg aaatttgcca aagaatgtca ctttgatcaa
    34021 tatgttttgt tgggcaaggg agaagagaat tcaggaggac gtacgcgacc agcattgctt
    34081 tgcgacctat tcgaagcttt tttaggcgcg ttatatcttg accagggatt cgacacgacc
    34141 catgcattca tcgaaaaagt gatttttcct aaagtcaaag caggtgcttt ttcacatgag
    34201 atggatcata aaacaaaact acaagaagtc ttgcaaaaat caggtgatgt atcaatcgaa
    34261 taccgattga tcaatgaaga aggtccagct catgaacgag tattttggat cgaagtttat
    34321 gtagatgatc aattgattgg cactggacaa gggaaatcga aaaaattagc agaacaagct
    34381 gcggcggaaa atgcattggc agcactgtaa aagtaagtga gggaaagctt tgtatttgaa
    34441 acgaattgaa atagccggtt ttaaatcatt tgcagacaag acagtcattg attttgaaaa
    34501 tagcgtcaca gcagtggttg gaccaaatgg cagcggaaaa agcaatatta cagaggctat
    34561 ccgctgggta ttaggagaac aatctgctaa aagtctgcga ggcggaaaaa tgccggatat
    34621 catctttgcc ggttccgata cccgtaagca gctgaatatt gcagaagtca cagtgatttt
    34681 agacaatagt gatcattatc tgccattgga gtacaatgag atcagtgtaa cccgccgtta
    34741 tcgacggact ggggaaagcg agtttttcat caataaacaa agctgcagat taaaagatat
    34801 ccaagaattg ttcttagatt ctggattagg aaaagaatcg ttctcaatca tttctcaagg
    34861 aaaagtagaa gcgattttca gtagtaaacc ggaagaccgt cgtgggatct ttgaagaagc
    34921 agctggtgtc ttgaaataca agcagcggaa aaagaaagca gaacagaagc tttttgaaac
    34981 agaagacaac ctcagccgcg tccaagacat catccacgaa ttggaagaac agttaactcc
    35041 tttggccgcc cagagtgagg cagcaaagga gtttttacgg ctaaaagaaa cactgactca
    35101 aaccgatgtc tctttgatgg ttgctgaaat caagacagca aaaaaagatt gggacaacaa
    35161 acaagcacag cttgcgaaat tcaatctaga attaggcaaa ctatctgagt cgatccaaga
    35221 acaagaatcc attttggcga agcagcgtaa agaaaatgcg caagccgatc gtctgatcga
    35281 aaaaaatcag caagtattat tagatctttc ggaaaaactg aagcagacag aaggacaaaa
    35341 agatgttttg caggagcgga caaagcatac acaaaaaagc tcgcaagaat atcaaacttc
    35401 attagcagaa gcacaaaaaa aggttaaaca ttttgaaaag cttcaagaaa gcttgatgaa
    35461 agcagcagca gaaaaagaaa cagagatcca aaaagctgaa gcaaatctca taaaaacaca
    35521 gcaagaatta gaaaaatacc aaaaatcaac gaaagaatta ttggcagaat taagagatca
    35581 atatgttgat ttgatgcaag aacaagcagc tgtaggaaac gaactgaagt atctagaacg
    35641 tcaatatata caagaaacag caaaaagcaa gcagacgtta gccaagcaat cggaagtaga
    35701 agcatcagta gaccgattga tcttacaaaa agaagaattg acacaaaagc aggcgcagct
    35761 aaaatcatct ttaactgaaa caaaagagaa gttagaaatg atccaacaaa acgggaaaaa
    35821 gttccaagaa gcattagcaa aagaacagcc taaaatgtat caattaatga atcaagtcca
    35881 gcagctacgt gctcgtaaga aaagccttca agaaatccaa gaaaactatt ttggttttta
    35941 ccaaggggtt cgattggtct tgcagcataa acagcagctt tcgggtattg tcggagcagt
    36001 ggctgaactg atcgatgttc ctgcagattt cacgttagct atcgaaacag ctttaggtgg
    36061 ggcagcccag catgtcatcg ttgaaaatga aaaagatgct cggcaagcca tcacgtattt
    36121 gaaacagcaa agaggaggaa gagcaacatt ccttccactg acgacaatca aaccaagaca
    36181 attaccggct catatattga cacaagcagc agctgtagaa gggtttatag ggattgccag
    36241 tgaacaagtc agttatcccg atcaaatcca aactgtggtt caaaacctgc taggaacgat
    36301 ccttttagcc aaagacttaa ctagtgccaa tgcaatcgcg caaacgatcc gctatcaata
    36361 tcgagtggtt tccttagaag gtgatgtgat gaatgccgga ggatccatga caggtggagc
    36421 gaataaacga ggaaaccaag gcagtttgtt tgtacaaaat caagaattga aacagttgac
    36481 tagtgaattt gaagaagcag ataaacaact ccaagcacaa gaaaaaaaag ttcaggagct
    36541 gcaacaagaa acagctcgtt tagccgaaga acaagaagtt ttgcgtacac gaggcgaaca
    36601 attacgtttt gaagaacaag aagcgacaaa tcagctacaa aacatcataa atgaacttga
    36661 acgttttgaa aaagaaaagc aaatctcaac ttttgagaca cgtgaactgc agcagtttat
    36721 cgaagattac gaaaagcaaa cgaacgaatt gaaagacaaa caaacagatc ttgaatcgca
    36781 acgacaaaaa atcgacgaag aaatcaaatc gttaagtcaa gaaagcgacc agatggaagc
    36841 cagaagagca caagtacaaa gtcaaaaagc acaagaacaa gcagatcttg ctgtcttgaa
    36901 agagcagttt aatcatctgc agatccagct ccgcggtgcc cgagtccaaa aagcagaggc
    36961 aaccgaacgt caagaagcga tagaaaagca gttggcgaca ttgacagcag acttttctga
    37021 tcatgaagtc acagaagaaa gtttggaaaa acaaattaac gaattatctg ctcagcgaga
    37081 aacattaaaa gccgagttgg caaaagccaa agagcagcga gatagaaggc aaaaggagat
    37141 cgataagctt gaagcagtct tggcagagcg taatcgtgag caaaaagcac gactgtcgga
    37201 acaatccaaa ttagaagtcc aaaaagaccg agctgaaatg attttagata atcatttgac
    37261 ctatctgcag tcagaatatc agctgacatt tgagaaagct tcccaagact atcaagaaac
    37321 aaccgatatc gaagacagta gaacaaaggt ttcatcctta aaagaacaga ttgaaaaact
    37381 gggaccagta aacttaaatt caatcgaaca atacgaacaa gtcagtgaaa gacatacatt
    37441 cttagcaaca cagcgagatg atctgttagc agcgaaaaac caattgtttg aaacgatgga
    37501 tgagatggat gatgaagtgc ggacaagatt caaagaagta tttgaagcta tccgtcaaga
    37561 attcaaaatt gtctttccaa atatgtttgg cggcggtaaa gctgaattag tactgacgga
    37621 accaactgat ttgctgaaaa caggtattga gattgaagta caacctcctg gcaaaaaact
    37681 gcaaagtcta agtttgcttt ctggaggaga acgagcactt acagccatcg cgttgctctt
    37741 ttccattatc cgtgtctgtc ctgttccgtt ttgtatctta gatgaggtag aagcagcgtt
    37801 agatgaagcc aacgtgaaac gttttggtcg ttacttgagc gatttccaag atgacacaca
    37861 atttatcgta gtcacacacc gcaaaggaac gatggtcgca gcagatgtac tgtacggagt
    37921 gacgatgcag gaatccggtg tatcaaaaat cgtttctgta cggatggaag atatcaatga
    37981 agaggcgaaa atcaacgaaa cgaaagtgta ggaacgaaaa tgatcaaatt agtagcaatc
    38041 gatttggacg gtacattatt aaatgaacaa aagctgattt cagatgagaa taaacaagca
    38101 ttagcacaag caaaacagca aggggtcaag atcgttctat gtacaggacg ccccttagct
    38161 gcgatggcgc attatctgca agaattagga ctggtagatg aaggtgacta cagcatcact
    38221 ttcaacggcg gtttggtaca aaaaaatgat actggtgaaa tcatggaaaa gaaagtgatg
    38281 gaagtatcag atatccaacg cttatacaaa ctggctcagc aattggatct gccactagat
    38341 gttttgtctg acaatgtggt tttacagctg cctagtgccc caaggaagca atccttgtac
    38401 aatgtgttga ataagctgct gcaattccaa ccagcggata taagcgatat tacagatgaa
    38461 tttgtgctta ataaggcagt aatcgcttat gaccaagaag aattagatcc taaaatcaaa
    38521 gaaataccag cagaattcca tgaaatgtat gagatcatca aaacaagaag tatgcttttg
    38581 gaatttatgc caaaaggtgt tacaaaagct tatggtattt ctttattggc aaaagatctt
    38641 ggtttgaaac aagaagaaat catggcgatc ggtgatgagg aaaatgattt accgatgatc
    38701 caatatgctg gactaggcgt agcgatggag aatgctgtgc ctttcgtcaa agaagcagca
    38761 gatttcgtga cagccagcaa tgaagaaaat ggcgtagcca aagtgatcca aaaatttgta
    38821 ttagagtagg gggagtcaaa tgggattttt tgataaaatc aagcgtgctt ttactggcga
    38881 agagaaaaca gaagaagttg aagtacagga gaagtacgac aagggtttag aaaagacgcg
    38941 taaaacattt ggtgaacgga tgaatgagtt gtttgccaat tttcgaacag tcgatgaaga
    39001 cttttttgaa gaattagaag aaacacttat cggtgcagat gtaggttttg aaacagcgat
    39061 acgaattacc gaagcattac gtcaagaagt gaaactcaga aatgcgaaaa aatcggcaga
    39121 agtccaaaat gcgatcatcg agaaacttgt ggatctctat gaagcggaag gaatcaatga
    39181 agtaaatgaa ctaaatatcc aagaagacgg actaacagtt attttgtttg tcggtgttaa
    39241 tggtgtaggg aaaacaacaa gtattggtaa acttgcccat cagttcaaaa acgaaggtaa
    39301 aaaagtattg atggcagcag cagatacctt ccgcgctgga gcaatcgacc agttagttgt
    39361 ctggggcgaa cgcgctggtg ttgaagttgt tcgtggcaat gcaggaggcg atccagcagc
    39421 tgtcgtattc gatgctttgg aaagagcaaa gacagagcag gcagatgttt tactagttga
    39481 tactgcaggc cgactgcaaa ataaagtgaa cttgatgaac gaattagaaa aaataaaacg
    39541 agtaatccag cgggaattac cagaagcacc ccaagaaaca cttcttgtat tagatgcaac
    39601 cactggtcaa aacgcgatgg ttcaagcaaa acaattcaaa gaaacaacag atgtgaccgg
    39661 tcttgttttg acaaaattag atggtacagc aaagggcggt atcgtacttg ctatccgtaa
    39721 tgaattgcat ttaccagtga aattggtcgg tcttggtgaa ggaatcgatg acttggagcc
    39781 gtttgatcca aatgattttg tcgttggatt gttcaaagga ttactaaaag aagaataacc
    39841 catgtctaaa aagcaggagc tgtgacaaaa gttgcagctc cttgtttgaa tgattgtttt
    39901 taacatagct gtgtttttga tgccttcatt tttatactta tttgtaagcg gttctcaaac
    39961 aatttcgttc tttttcttag actttttgat tataattaga ttcatatgaa ttggaggtca
    40021 cttaatgatg aattttaagc aattattatt gcatgtcaat gcgcgccctt ttatcgacca
    40081 agctcgattt ggtatagaac gggaaggaca gcgggttgat cttgcaggaa atctagcaaa
    40141 aaccgatcat ccagcaatct ttggcgatcg atcctatcac ccctatatcc aaacagattt
    40201 tagcgaaaca caaacagaga tgatcacccc tgttaccgat tctattcccg aattatttca
    40261 gtatctcgct gctgtttatg atgtgactgc tcgttctata ccgaaagaag agatgatctg
    40321 gccattaagt atgccacctg ccttaccgga aaaagacgaa gagatcatta ttgcaaaatt
    40381 aaaaaatttc gaagatgtct tgtatcgacg ttatttagca aaagaatacg ggaagcgaaa
    40441 acagatggta agcggtattc atttcaattt tgaatttggc gatgagttgc taagaacatt
    40501 gttcagccat caggaagaat ttcaagattt ttccgaattc aaaacagaac tttatttgaa
    40561 aacagcgaga aactttatgc gctatcgctg gatgatcact tatttattcg gtgcttcacc
    40621 aatgagtgag aagaactact ttttagatga atcacatccg caagaacctg ttcgcagtat
    40681 tcgcaacagt gcgctgggct atacgaatca tccaaatgtg aaagtttcct atgcttctat
    40741 gaaacagtat ttagcagata tcgagcgaat gatcgaagaa gggaaacttt cggaggagaa
    40801 agaattttat acaccgcttc gtttccgagg cggaaagaaa gtcgcagatt tagcaacaac
    40861 aggtgttcgt tatattgaat tgcggaatat cgatttgaat ccttatgcaa gattgggtat
    40921 caatccagag caagttcggt tcttacaatt attcctgatg tacatgttat ggacagaaga
    40981 aaaagaagac tgtgaccaat gggtagcaga aggtacgact cgaaataaca aagtagcact
    41041 agaacaacca tcagatcaaa cagaatttca tcaagaaggt agagaaattc ttgaaggaat
    41101 gaagcaaatg ctggttgaat tggattggtt ggattctctt tatttagtag aggaagcatt
    41161 gactcaaatg gatcatcctg aacaaacgtt agcagcgaaa ctctatcaag aagcacagct
    41221 atcgagtcag caagaagttg ctgtggcatt gggacatcaa tattataaag aaagccatga
    41281 acgtccctat cagttggccg gttttcgcga aatggaactt tctactcaga tatttatgtt
    41341 cgatgccatc caaaaaggtg tccaagtcaa agtattagat gagtcggatc aatttttgcg
    41401 tctgcaattc caagaccatg tagaatatgt gaaaaatgca aacatgacaa gtaaggacag
    41461 ctatatcgtc ccacttatca tggaaaacaa aacagtaacg aaaaaagtct taaaagaagc
    41521 tgggttccgg gtaccaggag gcgcagaatt ttcatccatg gaagaagcgg taaaagctta
    41581 tccgagattt gccgagcagg catttgtgat caaacctaaa tcaaccaatt acgggttagg
    41641 tatcacgatt ttcaaggaag gagctagtct ggaagattat caagcaggtt tagccattgc
    41701 ttttcgtgaa gacagttcgg ttttagtaga agaatttatg ccgggaacgg aatatcgttt
    41761 ctttgtgatc gacggagaag tccaagccat catgttgcga gtccctgcta atgttattgg
    41821 tgacagtatc cgaacagtga aagaacttgt tgaagaaaaa aatagtgacc ctttgcgtgg
    41881 aacgaatcat cgtgcacctt tagaattgat ccaattaggt gaattagaac aattgatgtt
    41941 gaaagaacaa gggttgacga tcgaatcagt tccccaagcc aatcaaattg tttatctaag
    42001 ggagaactca aatatcagta caggtggtga ttcgatcgat atgactgatg aattttctga
    42061 agcttacaaa aaaatcgccg tttctgcggt agaagcacta ggagctaaga ttagtggtat
    42121 cgatttgatt ataccagata aagaaatcga tcctacaact gataaaaaag catatgggat
    42181 catcgaagca aatttcaatc cagccatgca tatgcatgtt tatccttttg caggaaaagg
    42241 cagaagattg acgatgaatg tattgaaatt gttatatcct gaagtatttt aaaagaaaaa
    42301 gcttttgaca gattgtccta tttgatgtca atctgatcaa aagctttttt tgcatgtaaa
    42361 aatttatgtg ttttttcgtt ttaaaataaa cgatcccaga agcttttttt cttttttggt
    42421 ttttcttttt cagctggcga agagttttct tctgggtatt ttttttcgat atcaatcaca
    42481 ggttcattta ctgcttcttt tgctgttaag agcaatccga attcctcagg atttgcagtg
    42541 acgtaatcgt tgactacagt gaaacggcta ttgcttttcg ttgctagctg gatatattgg
    42601 ttttggacag aaaggggtag agccccattc aagagtatgg aagcatctgg atgttttttg
    42661 agttctttta aaaagttttc tttgtttttt ggttggatca tttcagcaac agtcatacta
    42721 agatagcagc gttccctgaa tgtccctaaa tatttatgct gttcttcagg gttcactaaa
    42781 ggtgtaccat aaagtccctt atccaaatgg ctttttacat catcttgtgc cataaaaaat
    42841 accctccttc ttctctttgt ctttcttacg attatagcat attcccaata atacctaaaa
    42901 catatgaaaa agcggttgct tttgttcaac gattcactta aaataagaat gaaaatcatt
    42961 ctcaattaga aaggtggatt ggatgcgcta cggacgacta gtagcattat tagttatttt
    43021 aagtagtatt tcattgttca tcggagtatc gaatgtacaa ttgtcagaac tgctccagtt
    43081 agatgggcaa agcttacaaa tcttgctagt gactcgtttg ccacgaacga tttgtttgat
    43141 ccttgtggga gcgaccagta gtatttgtgg gttgatcatg caacatttga cccaaaataa
    43201 atttgtttca ccaacgactg cgggcacgat ggatagtgcg cgtttaggta ttttagtggc
    43261 tatgattttc ctacctggtg catccttgat tgtccgatcc ttgacagcat tttgctttgc
    43321 ttttgcagga acattgcttt ttttatccct tacgcgattg ttcctccaga aaaatcaatt
    43381 gatgcttccg ttgattggag tcatgttagg gaatatcatt ggttcagttg ctactttttt
    43441 tgcttatcaa ttccagttgg tacaaaatat gacttcatgg cttcaaggga attttgcgac
    43501 tgtgatacga ggaaattatg agttattgta tgctgttgtt ccattgttgc tcttggtttg
    43561 gctatttgct taccgattta cgatcattgg tctgggcgaa tcgtttgcag taaatctggg
    43621 aatagattac cagaagatgc agtttttagg cattggctta gtatcattgg ctagtgcagt
    43681 catgttgatc atggtaggaa gcattccttt tatcggagtg atcattccga atcttgtctc
    43741 tagaatatat ggagatcaag tgcacaaaac aattggcgta actgctttag caggtagttt
    43801 gttcttagta ttttgcgatc ttgtcgctcg cgtgttgatt tttccttatg aaataccagt
    43861 cagtgtgatc gttggaatca tcggtggggc tatcttcctt tatcttctga taaggggacg
    43921 acgatatgct taaaaaaaag ccatctattt ttattggtat gcttgttctt gttttatttg
    43981 ttacaggaat gtacttgacg atccatacat atggaaactg gcattttgca tgtgcattga
    44041 ggagtaagaa aatttttgca tttatccttg tctcgctagc tgtcagcagt gccacaatca
    44101 gctttcagac aattacgcat aaccagtttt tgactccttc agtattggga cttgagtcgt
    44161 tatatgtcct tgtccaaacg gtccttttct tctttatcgg aggagtgacg atgcttcagc
    44221 agacaggtac agtttttttc ttattgaacg ttgggctgat ggtcgggctg agtctattgt
    44281 tatttttctt tcttttgaaa aaaatgagag cgaatctttt tttattactg atgtcaggga
    44341 tgattttagg tacgcttttt ggtagtgtca gtaccttttt acaagtcatc atggatccga
    44401 atgaatatga tttgcttcaa ggcagattat ttgcaagctt tggcaatatc cagagtcagt
    44461 atcttttgcc tgcttctttg atcattatcg gctgctggta cctgttattt cgatatcgac
    44521 atgtgctaga cgttttccat ctcggaaatg aacaagcagt aaacctcggg atagacacag
    44581 atcgttttga atttttgatt ttatgttgtg tcagtctttt gacagggaca tcaacggctc
    44641 ttgtgggtcc agttactttt ttagggttta ttgtcgcaaa tatcagttat cgtgtctttt
    44701 ctacttatcg tcatggtcag ctatttatcg gaagctttct ggtagctatg ctgtttctga
    44761 caggaggaca gctcgcagta gagcagattt tcggctggaa tacaacagtg agtgtcgtcg
    44821 ttgaatttgt cggaggaatt tattttgtca caaaattgat tcgcgaaagg aagagtatcc
    44881 tatgattgat ttacaaaagg tcaataaact gtaccatgga aaatcagtgg ttaaagatgt
    44941 acagttaacg attcctgaaa agaaattgac tgcttttatc ggtccaaatg gtgctggaaa
    45001 gtcaacggtg ttgtcgatga tcagtcgttt gataccaaaa gatacaggtg aaatctattt
    45061 agaccataac gaagtaaagg cttggaaatc caatgaatta gccaaaaaat tatcgatcct
    45121 acgacaatcg aatgaaataa atgtccaaat caccgtgaaa gaattagtag aatttggacg
    45181 atttccttat acgaaaggaa aattgacgac aaaagacgag gaaatcgttc aggaatcact
    45241 ggaacacctt gggttagaag aaatagcgga tcaatcgatt gacactcttt caggcggtca
    45301 actccaacgt gcgtatattg caatggtgct agcgcaagac acggattata ttttactgga
    45361 tgaacctttg aacaatctag atatgaattt tgcggttcaa atcatgcaga ttttaaaaaa
    45421 tttagtacaa gaaatcggga aaacaattgt tattgttctt catgatatca actttgctgc
    45481 aagttatgca gacgaaattg ttgcaatgaa agatggacag ttatttacgc aaggaacgac
    45541 ccaagaaatg ataaaaaaag atgtattgga tgaattatac gaaatggaca tacggatttg
    45601 tgagattgaa ggccgcagat tctgtcttta tttctaaaac taacattagg agagaagaga
    45661 tgaaaaaatt agtagtaggt atcttgattc tagcatcatt tggtttagca gcatgtggaa
    45721 atagcaacaa caccagtcag gcagacacaa aaaaaagcag cacacaaact gaaactacat
    45781 tgacgataac agatagtaat ggagaccaaa tcgaggtgcc aaataatcca gaaaaagtcg
    45841 tcgtattcga caatggttct ttagatacga tggatgctct tggtgttgga gataaggtag
    45901 ttggagcagc tacaagcagc cttcctgagt atctttcatc ctataaaaaa gtagaatcag
    45961 caggtggaat aaaagaacca gacttagaaa aaattaatca gcttcagcca gatctaatca
    46021 tcatttctgg ccgacaaaga gattttcaaa aagatctaag tcaaattgct ccgaccattt
    46081 tcctttcttt agatgcgaaa aatccatggg aatctttcca gcaaaatgtc actgctttag
    46141 gggagatctt tggtaagcaa gaagaagcta aaactcaatt agaggaatta tctagtgcaa
    46201 tcgatcagac gaaaaagaaa gcagaagcta ctgacaaaaa agcactagtc acacttgtga
    46261 atgaagggca attatcagcc tacggatctg gttctagatt cggtttcatc catgatttat
    46321 ttggctttga acaagcagat gatcaaatcg aagcatccac tcacggtcaa agtgtttctt
    46381 atgaatatgt gctggaaaaa aatccggata tcttatttgt agtagacaga acaaaagcta
    46441 ttggtggaga cgacagcaaa gatgatattt ctgccaatga actggtagca caaacgaatg
    46501 ctggtaaaaa tcagcagatc atctcccttg aaccagatgt ctggtattta agcgggggcg
    46561 gtttagaatc aatgaaactg atgatcgaag atgtgaatca agcatttaaa tagcataaat
    46621 aacagaggat taaactctca tactatgtaa caataatgtt tcttacattc ttaaatagca
    46681 agagcctatc ctcaaagaag ttatcaaaaa ccatccgtaa aatcgtattg atgattttac
    46741 ggatggtttt tatttatttg agaaatcttt tttcaacgtg aattcattat ctacatcata
    46801 cgggttgatt ctagaatggg gagtggcaaa aaatagtgtg atccattttt tcagcatcaa
    46861 gatcgcctcc tttgatttga atcaaaggta caaagcgaaa cttagataaa acttaaattt
    46921 agatattttt attttgtacc gatctcttct ttaaacgatg ttccatctgc tgcttctcgg
    46981 caataagtcc actagactag aaaatatgag aagctatttt ctgtccagcg ttcttattac
    47041 tcaaagcaaa tcgcagttgt cacaatctct tctaaacgat gttccatctg ctgcttctcg
    47101 gcaataagcc cactagacta gaaaatatga gaagctattt tctgtccagc gttcttatta
    47161 ctcaaagcaa atcgcagttg tcacaatctc ttctaaacaa tgttcaatca gctgaccttc
    47221 ggtattagct caaagcactg atttcacaac ctctatttag gcatgtgtct cagcaagcgg
    47281 ttgatagttg atgatctgca tttttcgata aaaatcggcg ggaagcttac tccaccgttt
    47341 taataattga tagaaataac tctcttctgc tttgatttta tactcgctta atatcaatcc
    47401 aaaactattc gttttttttg aagctaattt tttataaata tccaatgctt tggttttatc
    47461 ttcattgaca aagagtgttt ttacttcaat ataagaaccc tcgatatttt gtgtttcttc
    47521 gataaaatag atgtttttta tatattcctt catagtgatt cctccaaaga agtcttttat
    47581 ttgataagtt tactctaccg aagagttgtt aataatccgt gaacaaaaag taattctttt
    47641 tccaatagtt gttaaaggtt ttttattttt tatagtattt tttgttattt aagaaaggaa
    47701 taaggttaaa caaataacag gttgcttttt gggtcttttt ccgttcaaga aactgaacga
    47761 agaaaaggga aagttgtctc ttttgtgata agagaaatca taataaacga atgacttact
    47821 ttccaataaa ttgagaacag tcagaaccag acaaattagt tgcatctgat gaataaagtg
    47881 attattctat gacatgaggt gatacagatg aaattagaag tgacaaaaga agcacaagaa
    47941 gtattgaaga ataaattaga agcagacgat caacttttat tagatatcga aaacggtgac
    48001 ggtccatttg cagaaagcca agtcagttgc caattggata cggcatttcg attgatcatt
    48061 gtcaaaaaag atacacaaac agatctaagt ctttattctg tagtggctga tacaccagtt
    48121 ggaccaatca aaatcaaaga cagtgcaata ctttacatgg atgatccatc cacacttgct
    48181 ttagaaccaa cttataatag tttacaatta aaaggaccaa gcggcttgag aaaaggcaac
    48241 ttgcaagttg ttcgaaaaga ctagagggat aaaatgggaa aattggcgat catcagcgac
    48301 ctacatgtgg acatcaataa attcggcgaa tcagagctga tgcagctttg gcaagttttg
    48361 caaaagcaca agatcactcg gcttcatcta gccggagata cggctaataa agtagaccgt
    48421 tgcctagctg ttgtcgaatt tttcgtcaat aaaggattat ctacgacatt tcatttcggc
    48481 aatcacgagt tggcagatgt gcccaatgaa cagatgatgg accattttcc agacccacat
    48541 tttttaaatg aacggtatat tgctttaaat gagcagaccg ttcttttagg gatgaatggc
    48601 tggtacgact atcagttttc cgaattgaaa gattacgagg caatcgtacg aatgaagcgt
    48661 ttgtattggt atgatcggtt catccagcgt gggaaaacag atctcgaggt caatgcagaa
    48721 atgcttgcag ctgcaaaaaa tttgctagac cagctggaag caaaaaaact tgaggtgatt
    48781 ttatccactc atttcgttcc taaacgggca tttatcatgt atcaatctgc tccttatgag
    48841 cgttggaaca aattaaatgc atttttagga tcagaatcat tcggagaatt acttgaccgt
    48901 tattcaaata tcaaacaagt agtttttggc catacgcatc gtcgctttga agataaatcc
    48961 atcggtcaca cgatttacag ctgcagacct tttggttatt attatgaatg gcagctgacc
    49021 cgagattttg tcttgaaaga acagttgcta gacagctatg atcctatgaa attacgtgtc
    49081 ctcttgcgtg cccatcaccc agcttttcag gcctatcaaa cacaacattt gcaagaggaa
    49141 tttgaacaag cgatgacaat cgttccgtat tgagacagca ttagtaatgt gtaaaagaaa
    49201 ataccttgta aaacataagg ataagtaaga gcagtagatc catttatcgt ggatatgctg
    49261 ctttttttgc ggaaaataat cagcgaatgt ttatttgatc ggatgatttg taactcgcag
    49321 agtactagat gcaagcgtgt attctttttt tgaacgataa tcacaaaaaa aaatataata
    49381 tacatttttt atttaattat aattaatatt gattgaagtc taggcagtca agtcacattt
    49441 tgatagatag gagggggact tacgaattat tttaaaggct atgacagctg tatttctaga
    49501 ttgtgtttgc atcaagttgc aataaaaact agaaatcaaa tcgggctgat aatcatttat
    49561 aactaatcga tacataggac caaatatagg tctatgttct tttatttcat aagtatcgta
    49621 aaacagaatt ttgctatgga ttaatccaat cgactgatat gtttagtaaa taaagaaaga
    49681 ggaatgtcaa tgatgaaaaa agaaatcgta ttaacagcag caatgatgtt attcagcatg
    49741 gtagcaagta cgacttttgt ttctgcaact gaagtatacc caaaggaata taacacagaa
    49801 ggaacgatta catttgaagc aggagatgag ggtgtaactc ctcctgttga tccagagaat
    49861 cctgatccca ataaacctgt cgatccatca gatcctccaa gccctggaac aggaggggca
    49921 ttatcgattg attatggatc aaaattcaaa tttgggactc aaaaaatttc tactgcggat
    49981 aaaacgtatt atgcagctgc tgatgtgatg aacgatgggt ctagaaaacc gacatatgtc
    50041 caagtgacag ataggagaag taccttatct gggtggaaat taagtgtctc tcaaccagaa
    50101 cagtttaaaa ctgccagtgg ggatgaacta gttggagcac agctgaaatt tacgaaaggg
    50161 caggctgttt ctttggttga tccaacatat acgccgcaaa cggtgaattc tgaattaacg
    50221 ttgacaccgg gaggaaacaa tacgttagca attaatgcta aatcaggaac aggtgtgggg
    50281 acttgggtct atcgatttgg tgcaaatgaa aatgaaaatc aagatgcggt acagctttcg
    50341 gtacccggta aatctgtcaa gttagcgcaa caatattcca ctaaattagt ttggacatta
    50401 gaagatacac ctaacaacta gtttactgaa aagaactgtt aaaaataaat acgtagtcat
    50461 attgtcttgc gaggtaatcg agcaaaaatt gtcaaaggct aggctaaatt tgtttggata
    50521 cgaatagttc atctaggaat ttaacgatca ggaggaaaag atatattgaa aaagaggagg
    50581 atcgtgctca ttttaagcag tctcttagtg actaatatct ttccgatcat agggtactct
    50641 ttggaattga atcagttgga gcatggaaat agaagagacg aagaaagcaa actcacttcg
    50701 acattcgaca gtttaataga atccaaccag acacaagaaa gcagtgagga tttaagtatt
    50761 tcgagtagtg gagagaccac tgacaacgta gaagctgagg gttcggacaa acaaggacta
    50821 gaagatgcac caatttctgc ggttgagctg cctgacgatc ccaatattat ttctatcgat
    50881 aaaatttttc aaacacctat cggtactagc acgtccatat tggaaaatgg gaagttactg
    50941 cagttgaacc cagcagaaag gtctcaaaga ggagctattt ggtcaaataa gaagattagt
    51001 ttactctcgg attttacatt taaatcttat ttatacttag gaaatcaacg agatagagcg
    51061 ggagatggca tgacctttac attgactggc gatcctagaa tggctagtaa tcccagtcaa
    51121 gttattggat cgccaggtat gggaattggc tcatattcta ctcgttctgg ccaaccttac
    51181 attgcgaatg cgctctcgat tgagtttgat acgtataaaa atagtggttc ttctgatcga
    51241 atggatcgag agataactgc tgataataga gggcatggac atgtcgcttt tgtcacgcct
    51301 aaaccaaata ataataatta ttctggagag catactggcg tgacggtagc tcctacattt
    51361 ctttctaatg gcacatggcg cttgttaata attaaatggg acgcggagca aagaagtctt
    51421 acttatgatt tggaaggtgt cggtcgctct tctcggatta tacctgatct cattaggcag
    51481 tttggttcta cagaagtaaa ttgggggttt acttcttcaa caggtacttt ttttcaagaa
    51541 aatgctgtcg ctgtcacgcg acttccatcg aatgtcacat caacagctga tgtaaaagtc
    51601 aacgatagtg attatggggc catcgctgaa gctggaggaa acgataagat aactatcaga
    51661 aatacattga aggtcgaggg ggattttctt gaatataaga aaatgcagac tagtatcgac
    51721 ctcccacaag aattaactat tcccgagcat atcttgatca atggaaatca aattgatgcc
    51781 aaagatatct tgataaccgg aaatcgagtc acgctaaatc tgacagatta ttttattgct
    51841 ggagatacgt taataatcga attggagaca actttgcagg aagtaattcc tgaaaaagta
    51901 ctcactatgc attttgaata ccttgaaaac gggaatttga ttgagcaatc gaatgaaata
    51961 aacctaaaga tcgcaaagct gaaggagata gatatccatg tttattataa agataaagac
    52021 agtcagattg atattgctga aatgaaaaca atcactggga aaataggaga gaagtataaa
    52081 gaaactccta ttgatattga agggtatgtt tttgactcgg attcagcgaa tacagaaggc
    52141 atcttctccg aaaatacaga ggatatctat ttttattaca gaaaaggcaa actttatctc
    52201 tcaactgctc ctcaatatgt caattttgga aaacataaaa tatccagtag accattaagt
    52261 gaattcggac agttttcagg tgggttgaaa attatagatg aacgggcttt tggaagttgg
    52321 aaattacaat tgaaacaaga gaaagttctt acaaatggag attttgagct tccagaagct
    52381 ctttcctttg ttacctctga aaatacaacg gttataggga catccgctgt tacgattttc
    52441 gaaagtgatc aaaagggtga aagcgatttg tcctctcttt tagattctac agctcatcgt
    52501 ggaatcagaa tagatattcc tgtagaaaac caaagaatcg gaacctttga ggggaaacta
    52561 tcttggatac ttgcagatgt cccaggaaat taacaggaag agaagaatat aacaaaatta
    52621 ttgagtttca agaagggcac aggtaccata ggctcttgtg tcccacagag acaagatttt
    52681 gttatagtct tctcttacat atgattaaag gagcgatttt cttgagacca aaacaacaat
    52741 tatttataac actcctagtt attttagggg cactttttaa caatatatca gtgtcagcta
    52801 gtgcatttaa tttttcagtg acgccgataa cttcagagaa tcaaatcgac aagagaaaaa
    52861 cttacttcga tcttcaactt gatccggatc aggaagtaga agtaaaagcg gaattgagaa
    52921 atgatacaga aaaagaagtg aaaatcgata tttctgtgaa tagcgcaacc accaattcaa
    52981 atgtgatggt tgaatacgga aaaaacgaga ttgaaaaaga catgagcctg atctttgatc
    53041 tggtagatta tgtgagctat ccacagatag tgacgctaaa acctaaaagt gtccaaaccg
    53101 ttgcttttca tgtcaggatg ccgaatgagc gatttgatgg tgtattggct ggtgggatca
    53161 cattccaaga aatccagacg gaaaaggacc aaacagaaac taaggatcaa agcttatcga
    53221 ttgagaatga atacacctat attattgctt tgttgatgca acagacactg aacgaagttg
    53281 ctccgaacct tactcttcat gaagttaaac cagatcaaat caatgcaaga aatgtcatct
    53341 tagcaaacgt tcaaaatgat caaaaaacct atatcaatca agtagttatt gaaacaaaaa
    53401 ttacaaaaaa aggacattct gaagttttat atcaagagga aaaagaagga ttgcagattg
    53461 cgccgaatac aaatttttct tttccaactg ctttaaatgg tcaaccgcta accccaggtg
    53521 aatatcacct tacaatgact gttttaggaa atgaaaatga aaatggaaaa ttttcgagaa
    53581 aaaaaggaaa tactacgatc aactatacca atcaatgggt atttgaaaaa gattttacaa
    53641 tagacggaaa agtagccaag gaattgaaca cgacggatgt tacgattaaa aaagacaata
    53701 attggattta tatcttagta gcttcacttt tcttattgtt tattttatta tgcatacttt
    53761 tgtttgtttt gagaaaaaaa gaagagaaag aaaagtaagg ttaagataac aaatagtaaa
    53821 tttttattat tgtaggatgg ttgggctctt tttataacaa tataaaatat accattttat
    53881 taataaaaat gcatactagt aaatgatata attctaataa caggtttgat cgcgagaaag
    53941 gccaaataaa acgctctcca aaatgttaaa aaaaagacag gacgatgtat attatacaaa
    54001 caagaatcgc tgacaacagt gactcggatc caggaaatca gttttatccc cagctagttg
    54061 gtgaatgcat ggaaagtaat atacgtagaa agagctgatg actaatgaat tatgagtttt
    54121 ttttaagcaa agaagatcac agaagttatt cattacttaa atatttagaa gcaagctcaa
    54181 atttatcaga gtcaatatcg aatgttcaag aagagttgtc gctatcgaca tttctcttga
    54241 aaaaaacgat cgataagctg aaacatgatt tacaaaagtt cgatctagag aaaaatttgc
    54301 gagtaaccgt cagtgaattg gatatatgtc tggaaattaa tggaaaatgt tctagcaaag
    54361 ctctgttatc tcgttatata acggattctt tatctatgaa aatggtattg gctttctttc
    54421 aggaaaaata tatctcagta gaaaattttg ctaaacagca tcacgtgagt tattctgtgg
    54481 cttataaagt attacaaaga ctaaaaagaa atctaaaaaa atatcaaatt ttttttgaaa
    54541 agagaaagtt g
//
LOCUS       DACBZK010000009        54446 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.009, whole genome shotgun sequence.
ACCESSION   DACBZK010000009 DACBZK010000000
VERSION     DACBZK010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54446
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.009"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..588
                     /locus_tag="IVD66_000620"
     CDS             <1..588
                     /locus_tag="IVD66_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144866.1"
                     /translation="FLDMNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYF
                     GNTMGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLI
                     VGIYLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMA
                     VKELMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(828..911)
                     /locus_tag="IVD66_000621"
     tRNA            complement(828..911)
                     /locus_tag="IVD66_000621"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(875..877),aa:Leu,seq:gag)
     gene            1294..2511
                     /locus_tag="IVD66_000622"
     CDS             1294..2511
                     /locus_tag="IVD66_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP6144867.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            2695..3531
                     /locus_tag="IVD66_000623"
     CDS             2695..3531
                     /locus_tag="IVD66_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6144868.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     NEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            3607..4755
                     /gene="nagA"
                     /locus_tag="IVD66_000624"
     CDS             3607..4755
                     /gene="nagA"
                     /locus_tag="IVD66_000624"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAP6144869.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            4976..6034
                     /locus_tag="IVD66_000625"
     CDS             4976..6034
                     /locus_tag="IVD66_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014372913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HAP6144870.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            6053..7072
                     /locus_tag="IVD66_000626"
     CDS             6053..7072
                     /locus_tag="IVD66_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HAP6144871.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(7174..7890)
                     /locus_tag="IVD66_000627"
     CDS             complement(7174..7890)
                     /locus_tag="IVD66_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAP6144872.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(7859..8644)
                     /locus_tag="IVD66_000628"
     CDS             complement(7859..8644)
                     /locus_tag="IVD66_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP6144873.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(8635..9384)
                     /locus_tag="IVD66_000629"
     CDS             complement(8635..9384)
                     /locus_tag="IVD66_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAP6144874.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            9682..10206
                     /locus_tag="IVD66_000630"
     CDS             9682..10206
                     /locus_tag="IVD66_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144875.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            10222..11721
                     /locus_tag="IVD66_000631"
     CDS             10222..11721
                     /locus_tag="IVD66_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HAP6144876.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(11809..12411)
                     /locus_tag="IVD66_000632"
     CDS             complement(11809..12411)
                     /locus_tag="IVD66_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP6144877.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            12515..13471
                     /locus_tag="IVD66_000633"
     CDS             12515..13471
                     /locus_tag="IVD66_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HAP6144878.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(13776..14732)
                     /locus_tag="IVD66_000634"
     CDS             complement(13776..14732)
                     /locus_tag="IVD66_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP6144879.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFVSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            14906..15466
                     /locus_tag="IVD66_000635"
     CDS             14906..15466
                     /locus_tag="IVD66_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144880.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            15459..16283
                     /locus_tag="IVD66_000636"
     CDS             15459..16283
                     /locus_tag="IVD66_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAP6144881.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            16293..16910
                     /locus_tag="IVD66_000637"
     CDS             16293..16910
                     /locus_tag="IVD66_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HAP6144882.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            16928..17611
                     /locus_tag="IVD66_000638"
     CDS             16928..17611
                     /locus_tag="IVD66_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAP6144883.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            18294..19577
                     /locus_tag="IVD66_000639"
     CDS             18294..19577
                     /locus_tag="IVD66_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6144884.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            19593..20480
                     /locus_tag="IVD66_000640"
     CDS             19593..20480
                     /locus_tag="IVD66_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6144885.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            20497..21333
                     /locus_tag="IVD66_000641"
     CDS             20497..21333
                     /locus_tag="IVD66_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6144886.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            21336..21959
                     /locus_tag="IVD66_000642"
     CDS             21336..21959
                     /locus_tag="IVD66_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144887.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            21956..23248
                     /locus_tag="IVD66_000643"
     CDS             21956..23248
                     /locus_tag="IVD66_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP6144888.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      23607..23704
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            23820..24401
                     /locus_tag="IVD66_000644"
     CDS             23820..24401
                     /locus_tag="IVD66_000644"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HAP6144889.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            24404..25711
                     /locus_tag="IVD66_000645"
     CDS             24404..25711
                     /locus_tag="IVD66_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HAP6144890.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            26127..26615
                     /gene="purE"
                     /locus_tag="IVD66_000646"
     CDS             26127..26615
                     /gene="purE"
                     /locus_tag="IVD66_000646"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HAP6144891.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            26599..27732
                     /gene="purK"
                     /locus_tag="IVD66_000647"
     CDS             26599..27732
                     /gene="purK"
                     /locus_tag="IVD66_000647"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HAP6144892.1"
                     /translation="MINLVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVS
                     DCPAAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTD
                     LLAITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKG
                     QYVLKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHN
                     NILHETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRP
                     HNSGHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENK
                     PDWQFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            27745..29040
                     /gene="purB"
                     /locus_tag="IVD66_000648"
     CDS             27745..29040
                     /gene="purB"
                     /locus_tag="IVD66_000648"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HAP6144893.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(29220..29597)
                     /locus_tag="IVD66_000649"
     CDS             complement(29220..29597)
                     /locus_tag="IVD66_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144894.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            29853..30581
                     /locus_tag="IVD66_000650"
     CDS             29853..30581
                     /locus_tag="IVD66_000650"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HAP6144895.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            30581..30835
                     /gene="purS"
                     /locus_tag="IVD66_000651"
     CDS             30581..30835
                     /gene="purS"
                     /locus_tag="IVD66_000651"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HAP6144896.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            30837..31508
                     /gene="purQ"
                     /locus_tag="IVD66_000652"
     CDS             30837..31508
                     /gene="purQ"
                     /locus_tag="IVD66_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HAP6144897.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            31509..33731
                     /gene="purL"
                     /locus_tag="IVD66_000653"
     CDS             31509..33731
                     /gene="purL"
                     /locus_tag="IVD66_000653"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HAP6144898.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            33716..35155
                     /locus_tag="IVD66_000654"
     CDS             33716..35155
                     /locus_tag="IVD66_000654"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HAP6144899.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            35187..36230
                     /locus_tag="IVD66_000655"
     CDS             35187..36230
                     /locus_tag="IVD66_000655"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HAP6144900.1"
                     /translation="MANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGFGGC
                     FDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEPLYF
                     LDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFAVGI
                     AEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKKTLG
                     EELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSWPIL
                     PIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGKVIA
                     KEKHRVVFIGEER"
     gene            36227..36805
                     /gene="purN"
                     /locus_tag="IVD66_000656"
     CDS             36227..36805
                     /gene="purN"
                     /locus_tag="IVD66_000656"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HAP6144901.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            36802..38337
                     /gene="purH"
                     /locus_tag="IVD66_000657"
     CDS             36802..38337
                     /gene="purH"
                     /locus_tag="IVD66_000657"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HAP6144902.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            38353..39627
                     /gene="purD"
                     /locus_tag="IVD66_000658"
     CDS             38353..39627
                     /gene="purD"
                     /locus_tag="IVD66_000658"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HAP6144903.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            39749..40663
                     /locus_tag="IVD66_000659"
     CDS             39749..40663
                     /locus_tag="IVD66_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HAP6144904.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(40796..42361)
                     /locus_tag="IVD66_000660"
     CDS             complement(40796..42361)
                     /locus_tag="IVD66_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAP6144905.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(42354..43805)
                     /locus_tag="IVD66_000661"
     CDS             complement(42354..43805)
                     /locus_tag="IVD66_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP6144906.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(43819..44835)
                     /locus_tag="IVD66_000662"
     CDS             complement(43819..44835)
                     /locus_tag="IVD66_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6144907.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            45055..46143
                     /locus_tag="IVD66_000663"
     CDS             45055..46143
                     /locus_tag="IVD66_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP6144908.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            46197..47723
                     /locus_tag="IVD66_000664"
     CDS             46197..47723
                     /locus_tag="IVD66_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAP6144909.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            47725..48930
                     /locus_tag="IVD66_000665"
     CDS             47725..48930
                     /locus_tag="IVD66_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6144910.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            49187..50164
                     /gene="guaC"
                     /locus_tag="IVD66_000666"
     CDS             49187..50164
                     /gene="guaC"
                     /locus_tag="IVD66_000666"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HAP6144911.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            50428..51852
                     /locus_tag="IVD66_000667"
     CDS             50428..51852
                     /locus_tag="IVD66_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAP6144912.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            52313..53422
                     /gene="pdhA"
                     /locus_tag="IVD66_000668"
     CDS             52313..53422
                     /gene="pdhA"
                     /locus_tag="IVD66_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HAP6144913.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            53425..54402
                     /locus_tag="IVD66_000669"
     CDS             53425..54402
                     /locus_tag="IVD66_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HAP6144914.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
BASE COUNT        17403 a         9316 c        11921 g        15806 t
ORIGIN      
        1 tttttagaca tgaatatctt atttttattg ctatttttct taattttcct tctaacatat
       61 aggaaatgtc aaaactatta tgtgcgtata ttgactgcat taccgttttt cttaaacctg
      121 attatttatt ttggtaatac aatgggtcaa agctttactt acgtcaatgg aaataaaagg
      181 gcaatgattt ggagtagtag taacctgaat aatctcttta cagagttagg aacgaaactg
      241 tcactttttt atccaggtac ttggatagct actttagtag tcttggcatt attactatgt
      301 ttaattgttg gaatttattt aagttttgac aataagaaaa cttctatttt tttagttatt
      361 ttgatgataa tgggattttg ttcaaggtta attatgggat tttctcccac agtatgggct
      421 tccggaatgc ggacgtacta tatactttat gttgttatcg ccatcttagt actaatggca
      481 gttaaagagc taatgaaaag catgagtgta caaaaaaatg aatttatgca atttggatta
      541 accgtgcttg gtatttgtac ctttataata acggtgataa acagataata tacaaaaaat
      601 ccctcgcttt agtattaggt gagggatttt actcgttttt cgattaattg ttttaacact
      661 tgcaagtttc tacgagtagc ttgtttccga ccttcatata ctcacctcag gctgtttaca
      721 tgattgtacg ttctttttgt aaaggataca gtgatatgta tataatggca taaagaaacg
      781 ttcaaacaaa aaaactcgtg aagcaaaatt aacttcacga gttgtagtgc agatgatggg
      841 actcgaaccc acacgagcta acgctcacat gaccctcaat catgcttgtc tgccaattcc
      901 aacacatctg cgtaataata acacactaat gatagcgagg ttttacatag ttgtcaagct
      961 caaaaatggg aggacttatt aagatggaga aatatgacgg agaattttca ggactgggaa
     1021 tgatcttagg tgtattgatt ggacttgcat tcggacgttt tttgcttggt tttatgctag
     1081 gaatcatttg tggaatcgca atggattggg cagcgaatct atggaatgac tatcatgaca
     1141 attaagttct caacgcttgt ttgtgttttt ttaatactta cgtttttcct aaataagtgg
     1201 caaaattttc taggatggag tatgatattg aaatagtaaa taacaaaaaa tttggaaagt
     1261 tctaactttt tgaaatgagg gattggctaa gtgatgagag aatttgaaaa atccaacaaa
     1321 ttagaaggtg tcagttacga tgttcgcggt cccgttctag aagaagcgga gcggatgcaa
     1381 gaagagggca ttagtatttt aaaattgaac acgggaaatc ccgcaccttt tggatttgaa
     1441 gcaccaaacg aagtcattcg tgatttgatc atgaatgccc gtgactcaga aggctactca
     1501 gattccaagg ggatcttttc tgctagaaaa gcaattgagc aatattgcca actgaaacat
     1561 tttccgaatg tgacgatcaa tgatatctac accggcaacg gagtgagcga attgatcacg
     1621 atgtgtatgc aggggttgct ggacaatgga gatgaagtac tggttccaat gccggactat
     1681 ccgttgtgga cggcttctat tgcattagct ggaggcacac ctgttcatta tatttgcgat
     1741 gaagaggcag aatggtatcc tgatattgat gatatcaaat caaaaataac gagtcggaca
     1801 aaagctattg ttatcattaa tcctaataat cctactgggg cactttatcc aaaagaatta
     1861 ttagaagaaa tcgttgaagt agctcgacaa aataacctga ttatttattc cgacgaaatc
     1921 tatgatcgct tagtgatgga tggtctagaa catattccga ttgctacatt agcgcctgat
     1981 ttgttcgttg ttacgctgaa cggtctatcc aaatctcatc gtgtagcagg atttcgagta
     2041 ggctggatgg tcctaagtgg agataagtca cacgtcaaag gctatataga agggctgaat
     2101 atgttgtcct ccatgcgttt gtgttccaat gtattgtctc agcaaattat ccaaaccgcg
     2161 ctaggcggtt atcaaagtgt cgatgagctg ctcctgccag gcggaaggat ctatgaacaa
     2221 agagaatata tctataatgc aatcaatgat attcctggtc tttcagccgt aaaaccaaaa
     2281 gctgcttttt atatattccc aaaaattgat acaaagcgat tcaatatttt ggatgatgaa
     2341 aaattcgttt tggacttttt acatgaacat catattctac ttgtacatgg tggtggattt
     2401 aattggaacc agccagatca ttttcgaatc gtttatcttc ctaaaatgga tgatttgaaa
     2461 caaacagcta agaaaatgag agaattccta gcaacctatc gccaaaaatg attttaaaaa
     2521 ccaaattttt cagtaggagg gccacagaca aacacactga ggctctcttt ctagtggagt
     2581 tttcttaaat aactaaagta tattatttag ttgcaagtct tttcttgaag tttgcgactt
     2641 cctaaagtaa aatacgaata gaatgcgaat acgcatattt tggggaggat acttatggaa
     2701 acgttaatcg agtcctttgg aacgatcatt aaagagattc gaaaagaaca aaaaatgacg
     2761 caaaaaatgc tttcgcatga tatttgttca caaagtgtat taagtcggat cgaaaataat
     2821 gaggaactgc cgaatgtatt ggtgatgatg cagatttgtc aacggctagg ggtaacgatt
     2881 gatcatgtga tgaatctctc tcgaaaaact actcggacaa acgataaatt atttgaactg
     2941 ttggatagtt gtttccaaaa acgtgattat cggaagttag aacaagtact aaaatcttct
     3001 gatatttctg aaaatctgta tcaagcaact gactttcaac gctattatta ttatctcggt
     3061 gtttgcgaat tcacgttgcg tcaaaatatc tctcagtccc tttattattt gaaagaagca
     3121 ttaagctact ctagccaaaa agaaagaatc catgtttctg acacagaaat acaactgatt
     3181 agttgtatcg gaaaaatata tggtgtggca ggaaaaacgg ctgaagcacg ctactatttg
     3241 agtcgaagca tccaactgct gcatcaatca gctgatgaac gatcaaaaag tgaattttcg
     3301 caaatttttt ataattatgg aaatttctta ttccatcaaa atgaaatcaa cgaagcgtta
     3361 gaacaggtga atcaaggaat ctattgggct caagagaaga atagctacta ttacctcaat
     3421 gatttatttg tgcttaaaag cttaatatac aagcgtaaag aagaaccaga aagagcagca
     3481 ttctatgaag gcttagcaca agctgtgaaa caaatttcaa aaaatttgta aatggtgtag
     3541 accattcttg acttcttctc taaataagag tactttagag gtagaaaaac aaagggagag
     3601 aatagaatga gaacttttat ctatgctgac aaattctttt tagcgtcagg tgtcaaacat
     3661 gcaggctatc ttgaaattac cgatggactt tttggtgaat acaccaaaga actacctgag
     3721 ggagaagtca acatcattga ccaaagcggc aaatggattg ctcctggttt ggtagataca
     3781 catattcacg gctatatgaa tcatgatgta atggataatg atgcagaagg catcaaagtg
     3841 atgtctgaag gtctgttatc ttgtggagtg acttcatttt taccaacaac attgacgtca
     3901 agcaaagaac gtttaaaaga tgtagctgag acaatcggca aaatgtatca ggaagcacca
     3961 ggagctaaaa tcaaaggaat ctattttgaa ggtcctttct tcacagaaga acacaaaggg
     4021 gcacaaaacc caagttattt cggggatcct gatttggata ctttccatga atggcaagaa
     4081 gcttcaggtg gtttaatcaa aaaaattgct ttagcaccgg aacgtcaagg tgtagaagag
     4141 tttgtcaaac aagtgactga agaaggagta gttgtttctc taggacacag taatgctaca
     4201 ctagaagaag cgcaaaaagc tgttgaagca ggcgcaagtg tatttgtcca tgctttcaat
     4261 ggtatgcgtg gattgaatca tcgcgaacca ggtatggtgg gtgcgttatt atctttagaa
     4321 catgtctttt ctgaattgat ttgtgatggc catcatgtac atccaaatgc tgcgggaatc
     4381 ctaatggaaa aagcaggaca tgatcatgtc gcattaatta cagactgtat gatggccggt
     4441 gggatgcctg atggaaatta caatttaggc gaatttccag tagtagtaaa agaaggaaca
     4501 gcacgtctag aatctggcaa cttagctgga agtatattga aattgaaaga agcaattaaa
     4561 aatgttgtag actggggatt agcaacacca gaacaagcag tcatgatggc tagtctgatt
     4621 ccagcaatca gctgtaaaat cgatgataca tgtggaaaaa tcgctcaagg acgcgatgca
     4681 gactttatcg tattgaaccc tgatatgaca ttggaagcaa cttatctaga tggcgtggaa
     4741 cgtttccacg cataatataa tttaagttaa ccttaaaact aaacttctta agtttggttt
     4801 taaggttttt tttgtgttct agtaaaaatc actttacata agtttcaaaa gtttctttaa
     4861 tttcctattg ttcaataagt aacaatgtaa agataaaatt aaaaatgtta atacgtatta
     4921 gcaaaataaa agcttttttt attgtgaata aatgaacata attaggagga gaaagatgaa
     4981 cttatttgac atttttcgat cgactttgac agatatgtcg attgtcagtg caatcacttc
     5041 aacagttttt attatattat tagggtttgt ttgtagaaaa aaggggattt tttctgaatc
     5101 tgttggaaaa attctatcga aagtcgtctt aacagtggct ttgccagcac tggcatttcg
     5161 agctttcatg caagatatca atacagaatt actgatgcaa ggaatcaatg tcttgatttg
     5221 gggattagtt atttatatta ttcttattct agtttcaaaa ccttttttct taagctataa
     5281 aggggataag caaacaacgt tgcgtgtcct gacgatcttt ggttctacga cctttttcgg
     5341 aacgcctatc gtcagtgcga tttatggtcc tgtcggcgtg atgtattcct caattttcaa
     5401 tattggctac cgaatctttt tgtattctta tggatacata aaaatgagtg gcttgaagat
     5461 ggaagctaaa aatatcaaag cgatgttcgt caatccaatc attatcgcta cttttgccgg
     5521 ccttttcatt tggctgttcc aagggtatct gccacaagtg tcagttacag gtgcagaagg
     5581 agagataagc caagtagcgt ttttgcgaat tgaccagact gcaccgtggc tatttcagcc
     5641 gatggattat ttagctggtt taagttcacc attggcgtgg ctagcaatcg gcgcaacatt
     5701 aggtgaagta agcttcaaaa aagctgcatc tgaaaaaact tcatggtatt acagtctagt
     5761 caaagtggta tttgtacctg cattgaatat cgtgattcta gcagttttga cggcaacgaa
     5821 tattctacca gtcaattttg aagcactggc aacaatcgtt atcatgatgg ctacaccagc
     5881 tgcaacagtg gcagcagcct atgctatcag ttttgatagg gaggcacttt tagcctccaa
     5941 tgcatcctta ctgtcaacta tttttgctgt ggtactgaca cctgtatgga tcgttgtatt
     6001 acaaatgatt catggcatag gtttattttc ataagaaatg gaggaagaaa gtatgagaat
     6061 cgcatgttac ggtgttcgtc cgaacgagat agattttttt gaaaaattga atatttacca
     6121 ttatgatctc agtctttatg aagaactgtt gacacatgac aatatcgtgt cagcaaagga
     6181 ccatgatgct gtattgttga ggggaaattg tatagcagat gagaccaatc ttgcaaaaat
     6241 gcaggaatat gggattcgtt atgtttttac acggactgtg ggagtcaatc atatcgatct
     6301 acaagcggca gctgattttg gtatgacagt agcccgtgta ccatcgtatt cgccaaatgc
     6361 gatagcagag ttatctttga cttttgccat gatgcttttg agaaatactg cgtatacgac
     6421 gatccgaaca tctttcaaag attttcgagt ggatgagcaa atgtttagtc gtgaaatcag
     6481 aaattgcaca gtagggatca taggaacagg caggataggg ttgacggaag ctgttttgtt
     6541 taagggacta ggagccaaag tgatcggcta cgatattcat cagacagaag ctgctaaaaa
     6601 agtattgacg ttccactcgc ttgaagagtt attagccaaa agcgatattg tcagtattca
     6661 tgtacctcat atcccaggtg aaaacgatca aatgatcaat gaaggatttt tagctcaaat
     6721 gaaaaaaggt agcatcttga ttaatacagc ccgtggagag cttcaagata atgaagctat
     6781 tttaagagct ttgaaaagca atcatttagc tggttttgca accgatgttt ttgcaaatga
     6841 aacagaggtt tttttccgat ccttcaagcc atgggagacg attccagacc ctgctatcca
     6901 gcaattagta gaaatgtacc ctagagttct tgtaaccccg catgtaggtt caaatacaga
     6961 tgaggcatta tcaaatatga tttcgacaag tttcgagaac tttcgtgaaa taatagaaac
     7021 tggaaaaacg aaaaatgagg tatctcttcc taaagcccgt caattaagat aagaaaacat
     7081 ggatattcgt caataaaatg tttaaaaata gtccaagtaa acagttgtta cttctgtata
     7141 cttggactat tttgtatggg ataattcgat gactcaacag taatctgtga gctttttccg
     7201 cccattcttt gtcaattcat aacaggttag cggccggccg atttccaaat atttgattct
     7261 ttcgttcaat atatcttgtt ctactaaaaa attcaaatat ttcttgacgg atatacgtga
     7321 cagtgagctt ttttgagcca gttcttttgt tgaaaaaata gtatcttctt ttagaataaa
     7381 tgcacttatt ttttttaaag tcagttttga cagaccttta ggcaaatcga tgaatgatgg
     7441 tatttcgtga atgggagtgg tgtggttgaa tacttgatcg atcaatttct gatcggcttt
     7501 ttcagtcgtt tggattgtct gagagaaagc aagatacttt tcgatcgcca gctgaaaacg
     7561 ttgcaaagtg aacggtttga tcaaataatc taaggcaccg tagcggatca cattctttat
     7621 ggtttcgata tcatctgcag cagtgatcaa aatcactggg atatcatttc cttgctgtct
     7681 aagccaagat aaaaaatgga taccactttc gccaggcatg tatacatcaa gcagcagcag
     7741 atctgcgttt ttttgtctga aatatttttt tccttcttct acatttctga aactttcgat
     7801 tacgttcata ttagggatgc tttccacaaa agtacgattc aattctgcaa ccattggatc
     7861 atcttcgatt atcaggacat ttgtcatcat tttgatcttc cttttttggt aattctagat
     7921 agacgattgt accgccattt gtttgtttgg aaaattctaa aaatccaccg tggcgtttga
     7981 cgattgaatg gatgagattc aatccaaacc cacgattgat tcccttcgtc gaaaaaccta
     8041 gcgtaaatat tttttctgag atttcttctg atatcccgac accgtcatcg cagacggtca
     8101 cgatgaatac ttcagcttct gtgtcatagt ttaaatgaat ccggacctgt ccgtttcttt
     8161 catgtttttg tagcacggct tcttttgcat tatcaagtaa gttccctaac acttgcaaaa
     8221 gtgaatggat ggagtcatcc atctccattt tagggataaa agaatcgctt tctaacagca
     8281 tttcaacaga ttgttctttg gcttcgttta ttttgcctaa taaaaaaccg gcaattgcag
     8341 gtactttgat cagacttgag acttggccaa tctctttttt ataattttga tttagctgct
     8401 ggataaaatg ggtgacttct tcatacttct tcaaatcaat caaaccagaa atgacatgaa
     8461 gtttattcat gaattcatgg gtttgagctc tcatggagtt tatatattgt ttcgtccccc
     8521 caagctcctc cattaatttc attacttctg atcgatttcg taaagttgcg actgctccta
     8581 aaaaacggtc attgctaaaa agaggtgtaa cgctagaaat agtttctatc ccatttaaat
     8641 acatggattg agtccgaacg gtcgtttgat gctcaatcgt ctctttaaac aaaacgtcat
     8701 atagattatc actgattttt ttcctacttc gaaatccaat agctgctctg tttggtagaa
     8761 aatgtttttt gcaggtgtat tgatcaagag gatagtttta tcagaagaga tggctaagat
     8821 tccttcatct acttcatttt cgataatcgt tttttcactt aactgttctg ctatttcttg
     8881 tggttcaagt ccaagcagta cttttttcat tttttgggca agaaaaacgg cgcctatgat
     8941 gcctacgcta agtccaataa tcaatgaaaa aacaatcatt ttttgtccat ctttgacttg
     9001 attgtcaatc gtgttgtttg ttaagccaac acaaactgca ccaataatct cttgatcata
     9061 ataaataggg acgaaatagc ggaagccgaa ccctaacatt ccttcttttt cagagaaaaa
     9121 ttcttgtcct ccaatcactt ttttcacatc ttcatgactt gagaaaggaa gaccgatgta
     9181 acttgggtct gcgtgagaat atcgaatgcc ttcagggtcc atgacaacga taaaatctaa
     9241 attcgatgca atcatgattt catttgttat tccttgaatc gcatgtgtcg ggtcaccagt
     9301 ctgcagcttt ttttggatga gtttatcatt ggcaacgatt ttagcaatgc tagagatttt
     9361 atctgacaca ctagatcggt tcatcgaaag aataaaattc ctgatcaata tggcagaaac
     9421 aatcaaagaa acgaatgtgg agaaacaaac gacaaggatg atcgtgttct ggagctttaa
     9481 tggttttttc ttaaaaaaag gaaacatagg ctacctcgaa agaatttatt gtgaaaattt
     9541 taacatgaaa acaaaaattt aacaaattgt caacgataaa cacaaccttc ctataaaaaa
     9601 caccactgag tcggtaaaag aagctataca gaattttcaa acattggtat gatagacgta
     9661 gaaatggaag gaggcgtgta tatgataggg ggaatcgcac ttgagacgat ttattggtat
     9721 acattgctga tttgtgcagg attggcagtc ctattgatta tttttggaga tgtattcgat
     9781 tttgatggcc cgcttgatcc gatgcttatt atcccttggt taactttcac aagcttattt
     9841 ggttttctag gtgagcgttt aacagatcaa tcatctttat ttttatttat tgctagtgga
     9901 ggcatatcga tagtgttggt atttttgctt aatttctata tattgatgcc gatgaaacat
     9961 gccgaatcaa cgatgtcgtc ttctgaaaaa actctggaag gacaagtagc tgttgtgatc
    10021 acaccgatcc ctgtacgagg tatgggagaa attcagttga aaagtgttac cggttccatt
    10081 agtcgtccag cttgttttta cagcccccaa gaacagacag ctgagcgggg aacgaaagta
    10141 ttgatcattg agatcaagga aagaatctgt tatgtcatgc cttatgaaag catgataaaa
    10201 gcttaaagga gcgtgtgtta aatggaaata ccagttgttt ttatcgcgat cgcaatcgca
    10261 gctttgattt tactgatgtt gctgatcgtc tttgtagcga agtaccagac agcaaaaccg
    10321 gatgaagcgt tgatcatcag tggaagttat ttaggaagca aaaatgtgca cattgatgaa
    10381 agcaataaca aaatcaaaat tgtgcgtgga ggtggcgcat tcgtcttgcc agtttttcaa
    10441 cgttcgaatc ggatcagtct attatcgagt aaattggacg tctccacccc tgaagtgtat
    10501 acggaacaag gcgtaccggt gatgtgtgat ggtacttcga tcatcaaaat cggttcatct
    10561 gtagaagaga ttgctacagc agcagaacag tttttaggca agacaagaga agaactggaa
    10621 aatgaagcaa gagaagtatt agaaggacac ttgcgctcga ttcttggttc tatgactgta
    10681 gaagaaatct atcaaaatcg cgataagttc agtcaaagcg tacaagaagt cgcttctgta
    10741 gaccttgcaa aaatggggtt gatcatcgtt tctttcacta tcaaagaggt cagagacaaa
    10801 aacggttatc ttgactcttt agggaaacca agaatcgccc aagtcaaaag agatgcagat
    10861 atagcagaag cggaagctct aaaagaaacg cgtatcaaaa aagctcaagc agaaaaagaa
    10921 tcacaagcag ctgaattaca gcgacaaaca gagatcgcag aatcattaaa agaaaaagaa
    10981 ctgaaattag caacctacaa acaagaacaa gatgttgcta aagcaaaagc agaccaagcc
    11041 tacaatttag aaagtgcccg agcacaacaa caagtaatcg aacaggaaat gcagattaaa
    11101 atcgtagaac gtcaaaaaca aatcgaactg gaagaaaaag aaatcacacg tcgtgaaaag
    11161 caatatgatt cggaagtgaa gaaaaaagca gatgccgatc ggtacgctaa agaacaagaa
    11221 gcacaagctc aaaaagtcaa agaagtgact gaagccgaag cagaacgatt ccgtgtggaa
    11281 gcactggcag aagcggaagc caataagaca cgtttagctg gacaagcaga agccgaagca
    11341 gcactagcaa aaggaaaagc agaagccgaa gcaaaacaaa agatcgccaa tgccttcaag
    11401 gaatatggcg aagcagctgt cttgagtatg gttatcgata tgctaccgca attgatgcgc
    11461 gaagcagcac agccgctagg aaatatcgaa aaaatctctg ttgtcgatac aggaagcagt
    11521 tcaggagaaa ccagtggagc gaaccgagtg acaaattatg ccacaaattt gctttcttct
    11581 actcaagaaa cactaaaagc gacaacagga cttgacttga aggaaatcgt agagaatttg
    11641 tcgacacgtg ggactactag ccaagtaaat atgtatgaag cgccaaaaga ggcagaacaa
    11701 aactcgatga aggaagaata aagtagtaca cttcaccgtt caatcaaaaa tggaggaaga
    11761 ctttttaaag ttcttctctc cattttttta ttttattgca aaagaaaatt agtcctcgct
    11821 atttttcttt tgtttttgga tcttagcttc tatctcttgt aaatttgttc ttagcaatcg
    11881 ttctttcttt tggagttcga ccaaatcttc tgatagttct tccttctttt ctgtttcagg
    11941 aggacgaaga aagaaattga taccgattgc aatgaatgtc cctataaaag tatctagtac
    12001 acgttggata gcatacaaag cggattcgcc ttgagggatg ctcaacgcaa tcagcaacaa
    12061 cgtagctatt gcggaaatga taccggaatt attgttaata ccatctgaca cgacgatcac
    12121 aataataact agaataggaa gcaagatcaa ttctaccaaa aaatcattgt gaaaatagct
    12181 tttgacaaaa aaataaatga tagctaatgt accacctaat gtattgccga tgatcctaga
    12241 ctttccaaaa gaaacggttg tagtcaagtc ctgacgcaaa gaaaaaacag cagataatgc
    12301 agcaatcatc gggattcctc gttgagtcaa atgaaaaaac aagatacata aaaaaacagc
    12361 taaggcactt ttgatcgtac gcatacctag tcgaaaacgg ccaaattgca tagagattct
    12421 cctttttggt ctttttacta tcatacctaa acttttgtct gatagctagt ttttcattat
    12481 tcaagtataa ttaaaataaa aaagggggaa gtaaatgcgt ataggaatgc gaacagtcaa
    12541 aacagtgatc agtgtcttct tttcgatggt cacagcgggt agcttatcgc tgttgtattg
    12601 gccagctgca gggatcattg cattattaag tgtaggaaat accaagcgct ctacattgcg
    12661 tacgggcatg aatcgaatcg cagcctttat attagctacg gcaacagcac tgttcagttt
    12721 ttttgctgtt gggtatacta tttttggctt cagtcttttt ttattcctgt tcatcccgct
    12781 tgcctctcgc ttcaaattaa ccgaagggat agtagtaaat tcggttttgg tcactcatta
    12841 tttagtggag gaaaacatgt cttggcagct gatcggcaat gaagcgggat taatggcgat
    12901 tggattagta tttgctttgc ttgcaaatgt ttacatgcca gatcgtacga agcagctgaa
    12961 ggaaaaccaa atacagatcg aaaaagaatt tcgaaatatt ttgagacaaa tggcagaatt
    13021 tcttttatca gaaaataaag aagatgtgca gatcaaatgc gaacatttac tgacattcat
    13081 tcgcgaaagc caagaagatg ccagagaaca tcaagaaaac tactggctca gacagccgct
    13141 atactacgaa acttacttct ctatgagaag agcacaggcc aatgtgatta aagacatgct
    13201 ggaaaatcta gagagaatcc agcaaccagc ttattatgga aaacatatct atggtttatt
    13261 gatttatact gcagaaacat tttcagagtc aaatgatggc agacaaattt taacacgtat
    13321 tgaagaagtt tatgtattgt atcggcaaat gcctctgccg actagtcgcc ctgaattcga
    13381 ggatcgagca gaattgttcc agtttttgca gtcttttaaa agttttattg aaatcaaggc
    13441 agaattctcc caacaaaaaa tccaaaaata gaggttgtga attcagctaa tattcaggtc
    13501 aaaaagctga tttcacaacc tcttctttaa acggtgttct cctgtcaact cctcggtcac
    13561 aagtcacaat attcaacaaa catgagaagc tgttttttga aattgctcct tgtgactcgg
    13621 agctgaacgg taggctcaca acctctttct taaacggtgt tcaaaagctt tcctctgcgg
    13681 taataagtcc agccaaacga aaaataggag gagctatttt tgtttggctg ttcttattac
    13741 ttgatgcaga acagcttttt cacaaccttt taaaattaca tatttttcca tagaacttgc
    13801 atttgatcca agatttcgat gacatctttt gtcaagaaga gagagcgatt gggcaagtca
    13861 ccttcaatca tgtgtaccat attctttatt tcgtaattca ttgcttcaga tgtattcccg
    13921 ctttcgatga attcctttgt accatctgta aataagatct ccgcacgatc agcacgcggg
    13981 taatcagcaa tcgtcacata accgttctca aaggcaacga taccgacttt tggcattttt
    14041 gcctgaaaag tcaagctgac agcagcaagt tcattttctt tgttacgcaa gatagtgacg
    14101 gattgttcgt ccacgcctgt ttcaaaagga accattgtag aggcaactac ttcaggttga
    14161 gagctcaaaa agaaacgagc gaaagataca gcatacgtac cgatatccaa cagagctcct
    14221 ccagctaatt ctggattgaa gaaccggttt ttagggtctg gttctttgta actgacgaaa
    14281 ggtgcttgga tcatttttaa agcccccagt tttcctgtat ccattattga gcgtaactgc
    14341 tgataaagtg gcatgttgaa gattgtcatc gcttctgcta agatcaaatt cttttcttct
    14401 gctaagcgca tagcgtcagc cagttctttt ttattcatcg tgatggcttt ttcacataga
    14461 acgtgtttgc ctgcttccaa tgctgccaag atatggtcga tatgctgtct atttggtaca
    14521 gcaatgtaca cgatgtcgat ttcagcatcg tctaacattt cttgatagct tccgtaagct
    14581 tttggaatat tgtaacggtg agcgaagttt tccgcttttt ctgaagttct ggaagcaact
    14641 gctgttagtt cgctcgtctc ttgattgaag ctttcggcaa actcatgtgc gatggtacca
    14701 agaccaacga ttccccattg atattttttc atctgaaaac gctccttcat agttggattg
    14761 agtttcttgt ctgtctatta ttataacaaa aatcacgaag aataaagagg agaggacttg
    14821 aaacattaaa aaaaatgaaa gcagcgattt aagaggtgct ttttgatcaa aacttaagta
    14881 gaatagttaa aaggagggga taaacgtgca tcaagtatat attgatctta ttatgagtgt
    14941 attattagaa cagtttgaaa ctgaaaaaaa ttttttagat gaatacttgc tgatcagtcc
    15001 agaacaatgg caaaaatgga aagatggcga gaaaaatctg ccatctgaag cgatgcagaa
    15061 agtaaaaaat cttttcactg attatgaatg gatgctaacg caaaagattt tgcgtcaaac
    15121 gattattttt cccgaaaaac gaaacgttgc cgttgcagag tacaagcaaa tcaaaacacg
    15181 catcgcgcaa aaatggctta gcagcaaagc agcaaaagtc gagctgatcc ctttgaaaaa
    15241 taatcagcag gctggtagat accttgactt gaaagtaagt attcaatatg atgaatgggg
    15301 ctatgatgat attttgaatt ttcgtctgcc agcagatgtt caaaaacaga tcgaaggaga
    15361 aaaaatcgaa cttctcgatt gggtgaatga aaatctggaa gaaacttacg ttcatgaggc
    15421 gaatggggaa cgtgaagaac aacgaaagga tttttcaagt gaataaattt ttaggatttg
    15481 gagcagttgt gattatgatc gcagcaatgg gctatgttat ttttagcgat gatgattcgc
    15541 atgttcaagc cggcaatcaa gcagtcgaac gaacaagcac caaaacaact gctagtaaag
    15601 aaaagaacag tcaaacaacc agcagcaagg taaaggacaa agaaacaaaa gatcgtacgt
    15661 ccaaacaatt gccagatgtt aaaacagacg attggaagct agttttggtt ggtccagatc
    15721 acaaattaga aaaagaaatt gatgagtcta ctcaattggc atcattaagt aacggatact
    15781 tgatcgacaa acgcattgct ccagaatatg aagcatttgc caaggctgct gaagcagctg
    15841 gatttccatt agtgatggtc tcagcttacc ggtctgtatc atcccaacaa caagttttcg
    15901 aacaaaatgt ccaagatgtg atgagtcgtc aaggtgtatc agaagaggag gcgacaaaga
    15961 ttactaaaga aacgattacg gagccaggat acagcgaaca ccacacaggt ctggcagtcg
    16021 atgtcgtcga tcaaaactgg tacaacagtt atccttctac tgtattggat gcaagttacg
    16081 gagatcagcc tggagctaaa tggatcgcag ataatgctgc gcagtatgga tttatcgttc
    16141 gttatccaaa aggacacgaa gatataacta agatcacata tgaaccttgg cacttacgtt
    16201 atgtcggtaa agaaaacgct gagtatatca ccaaacacca attgacgcta gaagaatatc
    16261 tgaatgaatt aaatgaaaag taggaattga tcatggcgaa aaaaaagtgg aaaaagcaaa
    16321 agcgcaagaa tatccgttgg ccagcagtgg ttgccggtgt agcagtgata ctcttagcct
    16381 ttgttttttc cttgaagaat ctgtcttctc cttttactga taatcagcaa gaaaatgaag
    16441 cgcaatccca tcagcaattt attgaacggc ttgttccgca tgcccaagaa ctacaagatg
    16501 gttatggagt gcttcctagt atcattttag gacaagctat attagaatca aattggggaa
    16561 aaagtacctt ggctagcaaa tacaataatc ttttcgggat caaggcttat ggggatcaga
    16621 agaaagtaag cctggaaaca aaggaatttg ttaacgaaga atggataact atccaaggag
    16681 acttcaaagt gtatgattca tgggaacagt ccatggatga ccatacacaa ctgttcgtcc
    16741 aaggagtaga ttggaatcct gcgctgtatg aaaaagtgat tacggccacc aactatcagg
    16801 aagccgcaca agcattgcaa gatgcaggtt atgcgacaga ccccggttat gcgcaaaaaa
    16861 tcatccaggt catcgagacg tatcaattga atcagtatga ccggagatag caaaggagaa
    16921 gtggctgatg gcagaacaat ttacgccaga aatcatgacg gaattgagaa aagatatcgt
    16981 aagagtaccg gaaatcattt tagaagcaag cgggatcaag atatttggaa aattgatccg
    17041 ttcgatcatc tttactacgg atattgcgat catacgtaat acaaatgcga atgcagtaat
    17101 tgctgtgtat ccttttacac ctcatccagc gattactaaa agcattattg aggcagctga
    17161 cattccagtt ttctccggtg taggtggtgg tttgacacaa ggtgctcgtt cttcctacat
    17221 gagcatgttc gcagaagcgc aaggttcgtt aggggtcgtt ttgaacggtc ctacgccttt
    17281 agagacagta aaagaagttt gtcgagtagt tgatattcca gttatcagta cggtaacgtc
    17341 gaaatataca gaaatagatg aaaagttagc agctggtatt tcgattatca atatcagtgc
    17401 aggtaaagaa actgcagaag cagtacgcca ttttcgtaaa aaatatcctg aacttcctat
    17461 cattgcgaca ggtggtccaa cggaagaaag tattgctgag accattcaag caggagcaaa
    17521 tgccatcaca tatacgccac caagtagcgg agagcttttt agtcgtaaaa tggaaaaata
    17581 tcgggaaact gagaaaaaga atcatgaata acaggtgaga atcaaaagac gaggaagagc
    17641 agatagtggc tcttcctcgt cttttgtact ccagtactat ttgttcagaa ttcaaaaaaa
    17701 agagaaattt ttttgttttt ttacctgtaa tgtacataag aagagttaaa accttttgtt
    17761 attattagca ttctaacaaa aaaatgtctt gatttattga agcgctttct atagaatgaa
    17821 aaacgaataa aaactaaaaa aggcacccga caatttagta gcagctaaat tgtcggggct
    17881 tgaaaagtca gcgggaactg accaatcaag ttgccatagt caatgcttgt gcatcgacgt
    17941 gtatattgta cctaatttca tacagaatta ctagttattt ttctgttttt tagggaagag
    18001 cgcacacgaa gaagcatgct tatttagcta tgtcaaggat attgggcagt tgtctgatat
    18061 ccttttttct ttgcgtaatt atcctcccat cattgaagca agaagtgttt ttagcgatga
    18121 aagaagaatc agcactatct aatttttctt gaaagtattg agttgttcat cctaggcaga
    18181 acgataaggc aagtcttggt ttttattccc cttgaaaaag atcgtttaat aaatatgttc
    18241 tgtataaaaa tacagtatat tgaaaaataa caatggaagt agaggtgcag agaatgaaga
    18301 aaagaatgag aatcatctta gctttaagtg ttatgttatt cttcttgacg gcttgtgggc
    18361 aagaagatga caaaaaaatc acgctgaaca tggcttggtg gggttcgcaa gtccgacacg
    18421 atgcaacagt aaaagtaatc gagctttatg aagaaaaaaa tccccatgtg acgatcgatt
    18481 atgaatttta tgattatgaa ggatattaca caaaattagg tacactagca gcatcagatg
    18541 atatctggga cattttccaa ctgaacaatc aatttcctca atacatcaat cagattgaac
    18601 cattagatga atatgtggag caagggataa ttgatatttc taatgcagat gaatcctatt
    18661 tagcaacgac gacttacgac gggcaattag ttggactgtc taacggggtg aattcgtttg
    18721 cgattgctta caataaaaat atatttgaac aattaaatat ccctgaacca gcttcaaatt
    18781 ggacatggga tgaatttgaa caaatcagct atcaaatcac tgaagaatta ggaatctatg
    18841 ctatttcaag attcgaagat tttatagctg gctgtattat tcaaatacca caagttgaga
    18901 aaggattgaa tttttataat cgggaagatc tatctaacag cttgggattt gaaaatccag
    18961 actatctaac agattttttc cagctgcgta aaaatctggt agacaaaggg gcccatccag
    19021 aaccaggtgg tggagctgca agtacgacgg atctgtcttt tcaggcggtt agggatagag
    19081 aagcggcaat ggtgtttcta tcaagtaacc agttgacaga aatattgtca ggggctcctg
    19141 aagatatgga gattcagttg attaatccac ctcgcagaaa agcagatgga gaatctggta
    19201 tccctttacg ttcttcgcaa atgctgagta tggcaaaaag ctcagcccat aaagaagaag
    19261 ctgctaagtt tattgatttc tttcaaaaca gtgaagaagc caatgaaatt ttaaaaggag
    19321 aacgtggtgt accaatcatg tcgaatattc gagaacagct cgctcgtgca gatgatgcaa
    19381 ctttgcaagc gacatttgat tatttagaaa tgatttccga tatggacaac ggcgaagtga
    19441 atgtctttga tagtgctttg aatccggaaa ttcaagacca atacaatctt ttagttgaaa
    19501 aagtcattta tgaagaagta acagcagaag aagcagcaga gagtctttat gagtttgcgt
    19561 caaacattct aggatagcag caggaggaag gcatgaaaaa agaaaaacta aaacggttct
    19621 tggatcaaga caatgtggtc ggttacgtat ttgcttctcc attcatccta ggatttctat
    19681 tgataacagt gataccgatg atcttgtcac tttattattc gttcaccgat tatcgtttgg
    19741 gaaatccagt ctcatggatc ggcttggata attatataaa gatgctgagt gatgcccgtt
    19801 ttttgaactc catccgagtc acttttctct atgtatttgc atctgtacct gtgaaactga
    19861 tctttggtct attgattgct tatcttttaa cgaggaatat caaaggaacg actttctttc
    19921 gttctttgta ttatgtgcct agtttgatcg gtggcagtat ttctatcgct ctagtttggc
    19981 gggagttgtt ttctaaaaac gggttagtga atattttcct ggaacgatta ggcgcacctg
    20041 cgctttcctg gtttagcgat caaaaactgg tcatgatccc tcttgttttg atgtctgctt
    20101 ggcaattcgg ttcggcaatg atcatctttg ctgcaggtat caaagagatc ccaggctcgt
    20161 attatgaagc ggcagagatc gatggagcga acaaatggca gacgttttac aagatcacgt
    20221 tacctcttct ttcgccgatc attttgtata acttggttat gcagacaatc gcggcgttta
    20281 tgacttttac gcaggcattt atcattaccc aaggtggtcc gaatgatgcc acgaactttt
    20341 atgctcttta tgtgtataac caagcttttt cttttaattc tatggggtat gctagtgcta
    20401 tttcgtggat catgctgttg attatgggag ctgtcacctt tctgattttc aaatcatcaa
    20461 aaaaatgggt cgttgtgtga atgagaggag gaagaaatga ataatacagt aacgaaatgg
    20521 tttcaatacg gttttatttt gctattaggt ctagtcatga tttatccggt cttatggatg
    20581 atcgcaggtt cttttaaaac ggatcaagag attatgagtg gttcgctgaa tttgattcca
    20641 gagacttttc aatgggaaaa ttacgcaaaa ggatgggcgg ggtttgctgg aatttcattt
    20701 tttactttct ttaggaattc gtttgtcatc tctgcagttt cgacgatagg gacagttctg
    20761 agctcgactt gtattgctta cgcattatcg agaatcgatt tcaaaggaaa aagattctgg
    20821 ttcgtcgtca tgttagtaac gatgatgatt cctgcacaag tgattttgat tccgcagttt
    20881 attatttaca atcggctgaa tttggttggg acgtatgtgc cgctgatttt accacatttt
    20941 tttggacaag catttttcat ttaccagatc atgcaattca tggtcagcat ccccaaagag
    21001 ttagatgaat cagcgattat tgacggatgc agcaagtata gtgtctttac caaaattatt
    21061 tttcctttgc tgaaaccttc gatcatcacg acgatcatca tccagtttta ttggaaatgg
    21121 gacgacttca tgggaccatt gatttattta aacaagccga gatcttacac ggtatcgatt
    21181 gccatcaaat tatttgcaga cgctggatct agtacgactt acgcgagtat gtttgcgatg
    21241 tctacgttgt cgctgctacc ggtttttctg attttcttat tcttcaataa atatcttgtc
    21301 caggggatca gtacaagcgg tctgaagggc tgaatatgaa aaagccaata gaagagatgt
    21361 ttctttacaa gctcaactac tatgtctgtc ggattttttt aaccagtctt atcagtaatg
    21421 ctcttttcgc tttagttcta ggatgtttgt tcactttagg attagtgctg tctgctcgtg
    21481 ttgtctatct gatttatttt ttgatgatgt atccttctta ttatctatct gtccattact
    21541 tggcagaaaa aaaggtatgt tggaggaaag gaaaaatcaa acggatgtgt ttcatcatta
    21601 cgttgtttca gctgtttgtc attatttttg cagttgattg gtatttatta gtgggaaaga
    21661 ttggagcttg gtatctgatt ccttttctat tgtgtctgtt gctttttgta tcccatagtt
    21721 tttttagtac gctaattgat atctgcaaag aagataaagc agatagtctt gtttatttga
    21781 tcaaaaggaa tatctggctg ttgtcaaaaa acgtcaaggg gtttctgtgg tatttatgcc
    21841 ttttgtatgg actgttctgg tgtatacagc atgatttttt actcactgca ttactgtatc
    21901 cagggctgcc atttgtcaca gtattttgct taaaagaaaa ggagaatgac tttaaatgaa
    21961 gaaaaaatat gtacaagtcg gacttggtgg gagagcgcgt tttttttatg aggcaattgc
    22021 ctctacgtat catcaaactt gtgaactagt cggtttttgt gatgtatctc aaacaaggat
    22081 ggattatgca aatcggatac ttgtgaacaa gtatggacag aaaaaagtaa agacatgtat
    22141 gccatcacaa tttgagcaac tactggatga cgtacggccg gctgaagtca ttattacgtc
    22201 agtagatcga acgcatcatg attatatcat tcgtgcaatg aaaaaaggat atgatgttat
    22261 ttgcgaaaaa cctctgacta tcgatgagga aaaagctcaa gaaataataa cggtccaaaa
    22321 acagacggga agaagcctgc gagtcacttt taattatcgt tatgcaccgt atcacacgaa
    22381 gataaaggaa ctgatagaaa gtgatgtgat tggtgatgtg ttttctatcc acttcgaatg
    22441 gctgttaaat acgcaacacg gggcagatta tttcagaaga tggcatcgaa ataagcacaa
    22501 tagcggcggg cttcttgttc ataaatctac ccatcatttt gatctagtga atttttggtt
    22561 gaacagccgt ccccaaaagg tatttgcatt cggtggatta aacttttatg ggatgcataa
    22621 tgcggagaaa cgcggagtag aaatatttta cagtcgatgc tatggaagcg aactagctaa
    22681 agctgatcca tttgctatag acctgtcagc caatgaggaa ttgcgagaaa tgtatttaga
    22741 agcagaaaaa gacagtggat atattcgtga ccgcagtgta ttttccgatg atatctctat
    22801 tgaagataca ctaggcgtaa cggtcaaata tgaaactggt gcgattttga cgtattcgct
    22861 aaacgcgtat atgccgtggg aaggattcaa tgtttctttc aatggcagca aaggacggat
    22921 cgaaatgaaa gtgatcgaaa agtcttacat caatgcaggt ggagataaaa aggatgaagg
    22981 agcagccgtt cttcagtcca tccatgtcta tccgatgttc ggtgagccat atgaggtaat
    23041 cgtcgaacaa gaagcgggcg gacatggcgg aggagatccg cgtttattag atgatctatt
    23101 tggtgaagaa aaagaagaag atccgtggaa tcgggcagca actcacgtag atggtatttt
    23161 gtcgattttg acaggaatcg cagcaaatca ttctattgct tcaggaaaag cagtagtgat
    23221 tgacgagctt gtcagcttaa aagaataaga atagatttac ggaaattact tcccgtagtt
    23281 tataaaatct tgccttattg ccgataggct gtcttttgaa cactatttat tcggaaaaag
    23341 gggctatgac atgctttttg tcatgccttc tttttatgtg ggctgctttt ttagatagga
    23401 gaaaataaaa ataactattt aaacccgaac aaaaaggaat aatgcattaa aaatcattag
    23461 attttacaaa aaaataagta aaccacgttg tcagtttcag aaagtagtgt tagactgttt
    23521 tcaatatttg aaacaacatt ttttattcaa atatggcaaa ctgccttcac gtgcaaaaca
    23581 gttgcaagaa aatgaattta cactattatt agttttacat acctacttat atatcgtcat
    23641 aatatggatg acagtttcta gccagtaccg taaatgctgg actataagta aaagattggc
    23701 tatttcaccc ttcttttctt atgataaagt ggagggtgtt tttctttaac agaaacatag
    23761 taggtttttg cacaaaagcg gttatttcgg tattaataaa tgataaagga gcaaataaag
    23821 tgaaagaatt agttgaacgt attcaaaaag acggacgtat attaggcgag ggcgtattaa
    23881 aagtcgacag cttcgtcact caccaagtag accctgtatt gatggaacaa atgggaaaac
    23941 ggtttgcaga agtatttaaa gaacaaggaa tcacgaaagt tgtgaccatt gaagcttctg
    24001 ggatcgcacc agctttattt gctgcaagag aattagatgt tccaatgatc ttcgctagaa
    24061 aagcaaaaag tttgacgatg gatgaagaat tattgacagc ttctgtttat tcttttacga
    24121 aacaagtgac aagtacgatt tctatttctc gtaaattttt atcttcagaa gacaaagtat
    24181 tgattatcga cgatttcttg gcaaacggac aagcggcaaa aggattgatc gaattatgcc
    24241 agcaagctgg agcgcaagta gaaggaatcg ggatcgtcat cgaaaagtct ttccaagatg
    24301 gacgtcagtt acttgaagaa atgggattga gagtcgtttc tcttgcgcgt attgcttcct
    24361 tgacgaatgg acaagttgag tttcttgagg aggacgcata atcgtggaaa aagaaacaca
    24421 aaatggaaaa gctgcggttt tagggctgca gcatctgcta gcgatgtatg caggagcagt
    24481 agcggtgcct cttttgatcg gtacaggact aggctttaat caagaacaga tgacttattt
    24541 gatttcaatt gatatcttta tgtgtggatt agcgacatta ttgcaattga cagttaaccg
    24601 atttttcgga attggcttgc ctgtcgtttt aggatgtgcg atccaagcag tagctccact
    24661 gatcttgatc ggaaccaatg aaggagtagg agctatctac ggatctatta tcgcttctgg
    24721 gatctttgtt gtgttagttt ctggtgtctt ttctaaaatt aaaaaactat tccctcctat
    24781 agtaacagga acggttatca ccgttattgg tttgactttg attcctgtag caatcgagaa
    24841 aatgggtgga ggtaatgcaa cagcagctga ttttggtgac aaaacaaatc tgctacttgc
    24901 atttgtgacg attctcctaa ttgtaggcgt gcaaatgctg gcaaaagggt tcattcgttc
    24961 aatcgcggta ttgattggtt tagtcggagg aagcatctta gctgctttca tgggaatgat
    25021 tgatctgagc gcgattggag atgcgccgtt gttccatgtt ccacaaccct tttattttgg
    25081 taaaccaact ttcgacgtat ggtcgatttt actaatgatc atcatttcca tggtcagcat
    25141 ggtagaatca acaggtgtat attttgcact tggtgacatt actgggaaaa atgttggaga
    25201 agaagaattg aaaaagggat atcgtgcaga aggacttgcc gttatcttag gcggtatttt
    25261 caatacattc ccttatactg gcttttctca aaatgtcgga ttggttcaac tttcgggaat
    25321 caaaacaaga aaacccatct atttctctgc attcttcttg attgttttag gattattccc
    25381 taaaatcggt gcgttagcac aaatcatccc tgagccggta cttggtggag gaatgttagt
    25441 catgttcggg atggtggcag tccaaggaat ccgtatgctg ttggaagttg atttcagcaa
    25501 tgataaaaat ctattgattg ttgctgtttc tgttggattt gggctgggtt tcaatgttac
    25561 gccgacatta ttcagtcaaa tgccgcaaac attgcaaatg ttcactggaa atggcatcgt
    25621 aatgagtagc attacggcta tcatattgaa tttgatcttt aatggattga aaaaagatga
    25681 agaaatattg gaagaagcct tcaagaagta atagagcaaa agaaaggttg tgaaatcagc
    25741 gttttgacct gattgttaga gaaacaaacg gaaaaatagt tcctcgtatt ttgccgtttg
    25801 tttgagctaa taccgagggt cagctgattg aacaccgttg aaggaagagg tcgtgagcct
    25861 gccgttcatc tccgagtcac aaggaacaat ttcaaaaaaa agcttctcat gtttgttgaa
    25921 tattgttcct tgtgaccgag gagttggcag gagaacaccg tttatccata aaaaggaatg
    25981 tgacctaact tttgtcacat tccttttttt tatctttaat aaacacgaac aataaaatgt
    26041 ttttctttgt taacattcga aatttctttg acatcaaaaa aagtgattgt taaaatatga
    26101 atgtagaaaa actgggagga aaaacaatga cagcaaaaat ctctgtgatt atggggagta
    26161 cttcagattg ggaaacaatg aaagaagcat gtcaaatatt ggatgaattc ggtgtgtctt
    26221 atgaaaaaaa ggtcgtttct gctcatcgaa ccccagattt gatgtttgaa tatgcacaaa
    26281 acgctcgaaa aaaaggaatc aaaatcatta ttgcaggagc agggggagcc gcgcatctgc
    26341 cgggtatggt cgcatcaaaa acaactttgc cggttatcgg tgtaccggtc caatcacgaa
    26401 cattaaatgg tttggattcg cttctttcga ttgtccaaat gcctggagga gtacctgtag
    26461 ctactacagc aatcggaaaa gcgggagcaa ttaatgctgg actacttgcg atacagatgc
    26521 tttccatgta tgatttagaa ttggaggcta aattggctga aagacgttca atgttggcta
    26581 aaactgttat agaaagtagt gatcaacttg gttaaacctt tgttgcctgg ttcaacgatc
    26641 gggatcgtcg gtggcggtca attaggtcgt atgatggcga ttagtgcaaa agaaatgggc
    26701 tttaaagtag gtgtgctgga tcctgtgagc gattgtccag ccgcacaagt tgcagattgg
    26761 cacattgaaa gtgtctatga tgacaccttt gcgctgaaag agcttgccag aagaacagat
    26821 gtcattacct atgaattcga aaacgtcagt gtagaggcgt taaatgcgat tttacccatg
    26881 tcatttattc ctcaagggac agacttgctt gcgattacgc aagaccgcct gttagaaaaa
    26941 tcttttttgg aaacgaataa catcgtgatt gctccttatg caacgatcgt cagtccgacg
    27001 gatatccaag atgcgattga cgggatcggc tatccttgtg ttttgaaaac cactcgaggc
    27061 ggctatgatg gcaaggggca gtatgttttg aaaagtcggg cggatctagc tcctgccatg
    27121 gaccttttaa gagaaggaac ctgtgtttta gaagcatgga tcccgtttga aaaagagatt
    27181 tcgatcatgg tggcaggaaa tggtcaagga gatttcacga cttttccggt cgtggaaaac
    27241 atccaccaca acaatattct tcatgaaacg attgctccag ccgcgattga tcaggatgtg
    27301 atcgaggagg ctgagcgtat tgcccgtgtg attgcagaag cagtgagcct ttcaggtgtt
    27361 ttaggggtag aaatgttttt aacaaaaaca ggcgggctat atgtgaatga attagctcct
    27421 cgtcctcaca attctggaca ttattctatt gaagcttgtt ctatgagtca gttcgatgcc
    27481 catattcgag gtatttgtgg ttggccatta ggagaaaaag tacgtttgat aagcaatgca
    27541 gtaatggtca atgttttggg agaacaactg ctggaaagct atcgcttgat tgagaataag
    27601 ccagactggc aattccattt ctatggaaaa aaacaagcaa aaaaaggtcg caagatggga
    27661 catatcacta tcttgacaga agacatccag caaacgctgg aagaaatcaa acaaacgaat
    27721 atttgggatt agaggagaaa aaacatgtta gaacgttata cacgccctga aatggggaat
    27781 atctggacgg aagagaacaa ataccgtgcg tggctcgaag tcgagatttt agcagatgaa
    27841 gcttgggcag aacttggtga aatcccgcaa gaagatgtga aaaaaattcg tgagcatgca
    27901 tcatttgata tcgatcggat cttggaaatc gaaaaattaa cacgccatga tgtcgttgcg
    27961 tttacacgag cggtttctga aacattggga gaagaaagaa aatgggtcca ttatggtcta
    28021 acaagtacgg atgtcgtaga tactgcttat ggctatctca tcaagcaagc aaatgatatt
    28081 ttacgggaag acttgaaacg ttttacggaa atcattggcg aaaaagcaaa agaacacaaa
    28141 tatacagtga tgatgggtcg gacacacggt gtccatgctg aaccaactac ttttggattg
    28201 aaacttgcca catggtattc agaaatgaaa cggaacatcg aacgatttga acatgcggca
    28261 aaaggagtag aagcaggaaa aatctcagga gcagtgggaa cgttcgcaaa tatcccgcca
    28321 tttattgaag agtatgtatg taaacaattg gggatccgtc cacaagaaat ttctactcaa
    28381 gttctccctc gggatctaca tgctgaatat ttctcagcga tggcgcttat tgctacaagt
    28441 attgaacgtt ttgcaacaga gatacgcgga ttgcaaaaat ccgaaacacg tgaagtagaa
    28501 gaattttttg cgaaaggtca aaaaggttct tctgctatgc cgcacaaaag gaatccgatc
    28561 ggttcagaaa atatggctgg tctagccaga gtggtgcgcg gacacatggt cactgcctat
    28621 gaaaatgtca cattatggca tgaaagagat atttctcatt cttcagcaga acgaatcatc
    28681 ttgcctgata ccacgatttt attgaattac atgttaaatc gttttggcaa tatcgttaaa
    28741 aatctaacgg tctttcctga aaacatgaag cggaatatgt ctgcaacatt tggtttgatt
    28801 tatagccagc gcgttatgct gaaattgatc gataagggaa tgacaagaga agaagcttat
    28861 gatcttgttc agccaaaaac tgcgtacgct tgggacaacc aagtgcagtt ccgcccgctg
    28921 ttagaagaag atccaaccat cacatcggta ttatctaaag aagaaataga cgatgccttt
    28981 gattatcatc atcatttgaa aaacgttgac gtgatattca aacgagtagg tttggaataa
    29041 agaagagtga gttgcaaaat tcaattaaaa tagaatagca aaaataacca aaaaagaagc
    29101 agatccgtta gcggttctgc ttcttttagt ttattatatt ttcttatcaa taataggaac
    29161 ctgattttaa aagcggctac ctctttaccg tgcctcttta catacaaaaa atagaggaat
    29221 taagcgtaaa tggcttggct attataacta aaatgctggt tatggagatg ttgcagcaag
    29281 ttttcgagaa aagcgtattc catctcttgt ccattgaata agatctggat acgataatga
    29341 tttttgaaac gcttctgttc atgaatctga ctgattgaaa gttcgccttt gtgttctgtc
    29401 tgataaagaa aagtcctttt acggcattca gcacagcgct tggttgctcg gcggattttt
    29461 cggaatgtat aaaaactagt atctttattg cataaataaa cgtctttgat cgacagcaaa
    29521 tcattatata gacaggaacg ttcttcagct gttaattctg ataaaaaaag ctgaccttgt
    29581 tttattgcat cttccatcgg caagtgcctc ctcgaaccca ttatccaaat ttttagttaa
    29641 ttctaatata ccatcattaa gtataaatgt aaacgcttgt tgatggtata agattttcgt
    29701 ttctgataaa acacgaacat taaaagaatc taatgcctta aatgtacata tttttgttga
    29761 tttataaaaa gatgattgct aaaatttaaa gtgaaaaaac gaacaaaaaa cgatgtattt
    29821 gcttttaatg taaataaaaa ggagagacgt acatggagaa gaaagaactt ttgtatgaag
    29881 gaaaagccaa aaaaatatat cttacttctg atgagaactt gatttggata gaatatttag
    29941 atcaagcaac tgcgttgaat ggcgcgagga aagaccagat aagtggaaaa ggagaattga
    30001 ataatcaaat cacaagtgca attttccgtt atctgactca aagaggaata aaaaatcatt
    30061 ttattgaaca attgtctaaa accgaacaat tagcaaaaaa agtacaaatt atccctctgg
    30121 aagtggttat ccgaaatatt gcagcaggaa gtttctcaaa acgtctaggt gttcccgaag
    30181 gtaaagaatt catcaaacca atcattgaat tctactataa ggatgaccag ttggatgatc
    30241 catttatcaa tgaagagcat atctatttct tacaacttgc aaagccggaa gaaatcagtg
    30301 agctgaaagc ccaagcgttg gctattaatg aaattttgac cgaattattt gctaaggtcg
    30361 gtttggtttt agtagatttc aagctagaat ttggccggtc gaatggacaa attttgcttg
    30421 cggatgaagt aacaccggat acttgccgat tatgggatga acgtacgaat gaacatatgg
    30481 acaaagacgt ttaccgcaga gatctaggtg atttgatccc agtctatcaa gaagtatata
    30541 accgtctatc ggaactaact gaagaaaagg agcgagtatg atgtatttcg taaaagtata
    30601 tgtaacctat aaagattcag tgttagatcc tcaaggggag gcagtaaaaa aagcagtcca
    30661 tcgtatggga tatgaaacaa tcgaagatat ccgaatagga aaatactttg agatacaact
    30721 tgctgatgca gaagaaccaa tcgatacagt gattgaaacg atttgtgaca agctgcttgc
    30781 aaatgtaaat atggaaacat accgatatga aatcaaaaaa atggaggaag tataacatga
    30841 aatttgcggt catcgttttt ccaggttcaa attgtgacgc agatatgtta tgggcagttc
    30901 gcgagatcat gggcgctgat gccgaatttg tacggcatga tgagtcctct ttagaaggat
    30961 ttgatggggt tttactgccg ggaggattct cctatggtga ctatttgaga tgcggtgcga
    31021 ttgctcggtt ttctacaatc atggaagaag tgattcgttt tgctgaagaa gggaaaccag
    31081 tattcggtac atgcaatgga ttccagatat tgacagaagc aggacttttg ccaggtgtac
    31141 tgagacgaaa tgagtctttg cattttattt gcaaaactgt accattgaaa gtcaacccca
    31201 agacggcctt tacttcagag tatgaagccg acgaaataat ctatcttcca gttgctcatg
    31261 gggaaggaaa ttatttctgt gacgaagaaa cacttcaaga actaaaaaaa aataatcaga
    31321 ttgcctttac ttataatgac aacatcaacg gcagcgtgga aaacattgca gggattacga
    31381 acaaagcagg gaatgtgtta ggaatgatgc ctcatccaga acgtgcagta gaagacttgc
    31441 taggatcaga agatgggaaa cggttctttg cttccatttt aaaaaacttc ggaaaggtga
    31501 ccgtatagat gaaaacattg aaagaaccga cagctgaaga gatcaagaaa aaaagaatct
    31561 atgccgaatg gggattgact gatgaagaat atcgaatgat cgaagaagat atcttaggaa
    31621 gaatgcctaa ttatacggaa actggactgt tttctgttat gtggagcgaa cattgttcct
    31681 ataaaaattc taaaccggtt ctacgcaaat ttcctactag tggacctcat gtgttgcaag
    31741 gccctggaga aggcgcaggc atcgtcgaca tcggtgatgg actagcagtt gtcttcaaag
    31801 cagaaagtca caatcatcct tcagccgtgg agccttatga aggagctgcg acaggagttg
    31861 gcggaatcat cagagatatt ttcagcatgg gggctcgtcc aattgcgttg ctagattcat
    31921 tgaggttcgg cgaattagat aatccaagaa cgaaatattt actagaagaa gtagttgcag
    31981 gtatcggcgg atacggcaat tgtatcggca taccgactgt aggcggcgaa attgcatttg
    32041 atccttgtta tgaaggaaac ccattagtca atgcaatgtg cgtaggtttg attgaacaca
    32101 aacatatcca gaaagggcaa gccgctggcg tcggtaattc gatcatgtat gtaggtgcaa
    32161 aaacaggtcg cgacggtatc cacggagcaa cttttgcctc agaagaattt aatcaagaag
    32221 aagaacagca acgttctgct gtacaagtag gcgatccttt tatggaaaag ctgctgcttg
    32281 aagcgtgttt ggaattaatc ttgcatcatt cggattctct aataggtata caggatatgg
    32341 gagcagcagg acttgtttca tctagtgcgg aaatggcttc aaaagctggc tcaggactta
    32401 tattgacatt agatgaagtc ccacaaagag aaactgggat gacaccttat gaaatgatgt
    32461 tatcggaatc acaagaacgg atgttgattt gtgttaaatc aggagaggaa gaaaaaatcc
    32521 aagaactatt tcagaagtat gatctagatg cagtcactat cggtaaagta acagacgacg
    32581 ggcaatatcg gctatatcat caaggagaag aagtagcaaa tctgccagtc gatgcattag
    32641 ctgaagatgc accagtttat cataaagaaa tgaaagaacc agctcgaatc gtagaatttc
    32701 agcagttagc tccttatcag ccagttatcg aagaacctgg acaagtattg cttgatctgc
    32761 tgcagcaacc gacgattgct tcaaaacgtt caatctacga aacttatgat tcacaagtac
    32821 aaaccaatac agttgtccgt ccaggaagcg atgctgctgt gatgagggtt agagggacga
    32881 ataaagcgtt agctatgacc acagactgca acgcgcgcta tctgtatttg gatccaaaaa
    32941 tcggaggaca aatagcagtg gcagaagctg ctagaaatat tattgctagc ggtggtaagc
    33001 ccttggcgat caccgactgc ctgaactatg gttctcctga taaaccagaa gttttttggg
    33061 aattatcgac ttcagctgac ggaattgctg ctgcgtgtga aacgttagga actcctgtta
    33121 tttcaggaaa tgtctcttta tataatgaaa cggatggtca agcaatctat ccaacaccaa
    33181 tgattggtat ggtcggattg attgaggatc ataaacatat cactactcag gaattcaaaa
    33241 aatcagggga tctaatctat atattaggta agacgtttgc agattttgat ggcagtgaat
    33301 tacaaaagat gcagcttgga agaatcgaag gtgtgatccg aaactttgat ctatccattg
    33361 aaaagagaaa ccaagagtta gtattgacag ccatccaaaa cggattgatt gaaagtgctc
    33421 atgactgttc agaaggtggc ttggcaattg cactggcaga atcagctttc aaacatcagc
    33481 tagggatatc tgtacagttt gaattgtcct ctgctcaatt atttgcagaa actcaatcaa
    33541 gatttgtgtt gacagtcgca ccggaaaata agacacgatt cgaagaaatg atgggagatg
    33601 ctgctgtttt agcaggtaag gtgacggatg aagcgataat cgaaatttca gcaactgacg
    33661 gtcagatcaa aatagaaact gcagtagcaa gaaagtgctg ggaggatgca atcgtatgtc
    33721 ttatgaagtg aagagtttaa atgaagaatg cgggatcttc ggtgtttggg gtcatccaga
    33781 cgccgctagt gtggcatact tcgggctcca tagtcttcag catcgaggac aagaaggtgc
    33841 aggtatcgtg tccaatgatc gaggaaagct taaggggcat cgagatttgg ggctgctttc
    33901 tgaggtattc aaagatcaaa gaaaattgca gcagttaaca ggagaagctg caatcggaca
    33961 tgtacgttat gcaacagcag gcaatggaag tgtggacaat attcagcctt ttctattcaa
    34021 atttcatgat cagtcgatcg gcttagcgca taatggtaac ttgatcaatg ctcgttccct
    34081 tagaaaagag ttagaggaaa atggggcgat cttccattct aactccgata cggagatatt
    34141 gatgcatttg atccgacgaa gtgaagaaac agatttttta aataaattaa aaagtgcttt
    34201 gaatgaagtc aaaggtggct ttgcctattt attaatgaca gaaacggcaa tgattgccgc
    34261 tttggaccca aatggttttc gtccattagc aatcggacaa atgaaaaacg gagcatacgt
    34321 gattgcctcg gaaacttgtg cattagaagt tattggggca cgttttataa gagatgtcca
    34381 gcctggtgag atagtgatca tcaatgacga aggaatccag attgattgct ttacgaagga
    34441 cacgcagctt tctatttgtt cgatggaata tatctatttt gccagaccag attcaaacat
    34501 cgcagggatc aatgtgcata ctgcacggaa aaatatggga cggaatttag cgaaagaatc
    34561 gccagtaaaa gcagatatgg tcgttggcgt acctaattct tctttgtcag ccgcaagcgg
    34621 ttatgcggaa gctagtggaa tcccttatga aatcggatta gtaaaaaatc aatacattgc
    34681 ccgaacattt atccagccaa cgcctgagct aagagagcaa ggtgttcgaa tgaaattatc
    34741 tgctgtacga ggagtagtgg aaggtaaaaa ggtgattatg gtcgatgatt caattgttcg
    34801 gggtacgaca agcagacgga tcgtccatct tttgaaagaa gcaggggcaa aagaagtcca
    34861 tgtgaggatt gcttctcctc ctttgaaata tccatgtttt tacgggattg atattcaaac
    34921 gcgtaaagaa ctcattgcgg caaatcacac gattgatgaa atcaaagaat gtatcggtgc
    34981 agattcttta ggttttttaa gtgaagaggg tctgatcgaa tcgatcggtc tggaaaaaga
    35041 tgctccgtat tcaggattgt gtatggctta tttcaacgga gattatccga cgccgttata
    35101 tgactatgaa gaaaaatatc aggaatcact aaaagaaaaa gtatcgttct tttaaaagca
    35161 gaccaagaag ggagtatatg aattcaatgg caaatgcata cgcaaaagct ggcgtagatg
    35221 tcgaagctgg atatgaagta gtagaacgga tcaagaagca tgtcaaaaaa acggaacgtt
    35281 taggtatgat gggcgctata ggaggattcg gcggttgttt tgatttatcg gtctttcaat
    35341 taaaagagcc agtccttgtc tcggggaccg atggcgtggg gacgaaatta gcagtggcaa
    35401 tcgaagcaga caaacacgat acaatcggga tcgactgcgt agcgatgtgt gtcaatgata
    35461 tcttagcaca aggcgcagag ccgttatatt tcttagacta cttagcaacg gggaaaaatg
    35521 atccgttacg tttggaaaat gtagtaaaag gtgtagcaga tggatgtgtt caaggaaata
    35581 tggcgctgat tggcggagaa acagctgaaa tgcctggtat gtactcaggt aatgattatg
    35641 atctagccgg atttgctgta gggatagctg aaaaatctca attattgaca ggagaaacga
    35701 tcaacccagg agatgtgttg cttggaatag catctagcgg gattcattca aatgggtact
    35761 ctcttgttcg caaaattttc tttgagcagc agcagttttc tttatcatca aaactgccag
    35821 aattgaaaaa aacacttggc gaagaattgc ttgagccaac gaaaatctat gtttcttcct
    35881 tgcttccgct gatcaaagaa aagaaaataa aaggagctgc acatatcact ggtggagggt
    35941 ttgtagaaaa tatcccgcga atgttaccag aatctatggc tgcacaaatc aaacttggct
    36001 catggccgat tcttccaata ttcggctgtt tacaaaaata tggtgaaatt cctgagatgg
    36061 agatgtatga aatcttcaat atgggcatcg gtatggtcct ggcagtcgaa gaatcgaaag
    36121 taaaagaaat agtacacgaa attgagcaag ctggcgaaaa agtttatgaa atcgggaaag
    36181 tgatcgccaa agaaaaacat cgtgtggtgt ttataggaga agaacgatga gaatcgctgt
    36241 ttttgcttct ggaaacggaa gcaactttca agcgctagcc gattatctat cgaaaaaagg
    36301 attggaatct tcgattgact ggttgttttg tgatcagcct gaagcatatg ttttgaaacg
    36361 tgcaactgcg ttgagtgtac cggcagattg tttttcacct aaagaatttg attcaaaaaa
    36421 agagtatgaa gaagcaattt tgcataaatt gaaagaaaaa aagatcgatt tgatcgtatt
    36481 agctggatat atgcgaatca ttggaccggt attgctgaaa aattatgata aaagaatcat
    36541 caatatccat ccgtctcttt tacctgcctt ccctggtttg catggcatac gtgatgcctt
    36601 tgaagctgga gtaaaagaaa cgggtgtcac aattcattat atcgaccaag gtgtagatac
    36661 tggaccaatc atccggcagg aaaaagtgag aattgaacag gaggacacgt tcgattcttt
    36721 agaagaaaaa atccatagag tagagcatcg aatctatcca gaagtgatta gtgaaattat
    36781 tgaaaatgga ggctatctga aatgacaaga gcattgatca gtgtatcaga taaaactggg
    36841 attgtagcat tcgcccaagg tttgattgaa caaggagtag aaatcatttc aacaggagga
    36901 acaaagcatg cgttggataa agctgggatc aaaacgcttt cgatcgaaga agtgacaggg
    36961 tttcctgaaa tgatggatgg ccgtgtcaaa acacttcatc ctaaaatcca tggtggtctt
    37021 ttaggaagac gcgatctccc tagccatatg gaggcaatgg aaacggaaaa tatccaacca
    37081 atcgactttg tttgtgtcaa tttatatcct ttcaaagaaa cgattatgaa accagatgtc
    37141 gaaatagcag aagctattga aaacattgat atcggtggtc ctagtatgct ccgtagtgca
    37201 gcaaaaaacc atgaatttgt cacctctgtt gttgatccat ctgactatga agaagtactt
    37261 tcagaattac gtcagtatgg gcatacttca ctttctttca gacaaaaact agcggcaaaa
    37321 gtctttcgtc atactgcggc atatgatgca ctgatcgctc aatacttaac ggattgggtg
    37381 gaagaaaaag aaccggaaaa attgacactt acgtatgaac gaaaacaaac gcttcgttac
    37441 ggtgaaaata gccatcaagc cgctgccttt tatcagtccg ctcttctgga aaaatattcg
    37501 atcgcagcag caaaacaact ccatgggaaa gaactttctt ataataatat ccgagatgca
    37561 gatgctgcgc tacggatcat gaaggaatat gacgagccaa cggtagtcgc cttgaaacac
    37621 atgaatcctt gtggtattgg gacagcatct acgattttag aagcgtggga agcagcgtat
    37681 gaagcagatc ctgtttcaat ctttggtggg atcatcgttt tgaatcgaga agtagatctg
    37741 ccaacagcag aacagatgca taagctgttt ctagaaatca tcattgcccc ttcttataca
    37801 caagaagctt tggaattact gcaaaaaaag aaaaacatcc gattactgac agtagacttt
    37861 gcgcaggaag aaaatcaaaa tcgagaagaa acggtctcag tcttaggtgg acttcttgta
    37921 caagatcaag atctggcaat agaaaatgaa gaagagtgga aagtcgtgac aaaacgtaag
    37981 ccgactccag cagaagcaaa agcattagtg tttgcttgga gagctgtcaa acatgtgaaa
    38041 tctaatgcga tcgtactggc aaacgaacgt cagacagtag gaatcggagc cgggcagatg
    38101 aatcgagtcg gttcagtaaa aattgcgatt gaacaagcgc aagagaaaat ggaaggtgca
    38161 gttttagcta gcgatgctta ttttccaatg gatgattcgg ttgaatatgc agccaaacat
    38221 ggtataaaag caatcattca gccaggagga agcatcaaag accaagattc tattgatatg
    38281 gcgaataaat acgatctagc aatggtcttt actgatgttc ggcattttag acattagaga
    38341 ggagtcggat aaatgaacat tttggtgatc ggtgcaggtg gtcgtgaaca tgcaataagt
    38401 aaaaaacttt tagccagtcc gaaggtggat acggtgtatt gtgcgccagg aaatccgggg
    38461 atgacaaaag atggtatcaa ttgtgtcgct atcagtgagc gagatcattc agcgttaatc
    38521 cattttgtta agaaagaggc tattgattgg agtatcgttg gtcctgaagt tcctttgtta
    38581 aatgggatcg tcgatgattt tatggcggaa ggattgaaaa tcttcggtcc gacaaaagca
    38641 gcagctctga tcgaaggttc gaaaagtttt gctaaacaat taatggatac ttatcaaatc
    38701 ccgacagcta aatccagaag ttttgaatgt tacgaaaaag cagcagcgta tatcaaagaa
    38761 aatggtgcgc caatcgtagt gaaagcggac ggcttagcag ctgggaaagg tgtagtcgtg
    38821 gctaccacag tgaaggaagc gctggatgcg gcagaacaaa tgttgaacca gcatcgattt
    38881 ggggatagta gcaaaaaaat cgtcgtagaa gagtttttgg caggagaaga attctccctt
    38941 ttggcgtttg tccgtaatac caaggtgtat ccgatggtca tttcgcaaga tcataagcgg
    39001 gcatttgata acgataaagg gccaaataca ggcggaatgg gtgcttattc accagtaccg
    39061 caaatttcaa aaaagatgat tgaaaaagct gtggaagaag ttttaaaacc agcggctttg
    39121 ggaatgaaag aactaggacg ctctttcacg ggtgttttat atgcgggttt gattgctacg
    39181 aaggaaggac caaaagtgat cgaattcaat gcgcgtttcg gtgatcctga aacgcaagtc
    39241 gttctttctc ggttgaagag tgactttgcg caagtaatcg atgatttatt agagaatcgt
    39301 acagtagagt taaagtggca gcaagaagga tacaatgtag gcgttgtggt tgcagctgcc
    39361 ggttaccccg aagaatatga gacaggaatg gttctaccag attttctgga agaagagctt
    39421 tctgtttact atgctggagt ttcctcaaat aacggcaaac tagttggagc aggaggacgt
    39481 ctttatttag tagaagcata cggtgagacg atcaaagaag cacagaaaaa aatttacacc
    39541 gcgttaatgg ataaaacgac agatggaaca ttttatcgta cagatattgg agaaaaagct
    39601 gccaatagcg aactgatcgt gaagtaaatc agctgcttcc atttataaaa aatacaacaa
    39661 acataatcgg aagcgccgat tttagtgaag ccttttcata aagagtgtgg tacacttttg
    39721 ttgtgtatat aaataaggag gagttcagat gaaaaaaatt caattaggta cttctgatca
    39781 gaaagcagct gcagtgatct taggctgtat gcgtatcaac aatgcggaag atccagtaaa
    39841 agtgattgag acagcttatg aaaacggcat tgattttttt gaccatgcag atatttatgg
    39901 aaacggtgaa tgtgaagaaa tctttgcaga tgctctagca aaaacatcaa tcaaacgaga
    39961 agatcttttt attcaaacaa aatgtggaat cgttccaggt gtgatgtttg atttttctaa
    40021 aaaacatatc attgaatctg tagaaaaaag tttgacccgt ctgaaaatgg attatgtgga
    40081 tgctttactt cttcatcgtc cagatacatt ggtagaacca gaggaagtag ctgaagcgtt
    40141 tgatgaattg gaacggtcag gaaaagttcg ttattttggc gtcagcaatc aaaaaccaat
    40201 gcaaatcgaa ttgctgaaaa aatatgttcg tcaaccatta gtagctaatc agctgcaatt
    40261 tggcttgaaa catactggaa tgatcgatca agggattcat gtcaatatga cagatgaagc
    40321 aagtatcgat catgacggta gtgtacttga ttattcccga ttgcatgata tgacgatcca
    40381 agcatggtca ccataccagt atggattttt tgaaggtgta tttatcggga acgaaaaatt
    40441 ccctgaatta aaccaaacat tagaagaact agcagctaaa tatcaaacga caccaactgg
    40501 cttggcttct gcttggattt tacgccatcc agccaatatg caagtgatcg ccggtacgat
    40561 gaacgtaggg cgaatcaagg aaatcgctca agcttcagaa attaatatgt ctcgggaaga
    40621 ttggtacgaa ttgtaccgtg ctgctggaaa cattttacct taaagattgt cataagcagg
    40681 tcaaaagggc tataaattaa aaagacagaa taacttgaaa gctgttttca gcttcgagat
    40741 attctgtctt tttttattgc aaatggaaag agtatcattg tacggatttc gtttattagt
    40801 tatttttgtt tttaaggaaa agctgtgtcc gatattcttt tggagaaatc ccttgttttt
    40861 tcttaaataa ataactgaaa tagttagggt cattataacc aatttcaaaa gcaatatctg
    40921 aaatacgata gtctgattgc tgcaataatt tttttgctaa ttcgattctt tgttctgtca
    40981 gataatcgat gaatgtttgg ttaaacgatt gagaaaaaat cgtactgaaa tgagagggac
    41041 ttaatgcaac ttgttgagcg acccaagtta aggacatatc tggatcggta aaattttctt
    41101 tgataaaatc caatgcatgg ttcaaaattg gctgatattt gttccttgaa ggctgtgagg
    41161 gcagagcagt taagaaagaa atgaacatat aaactgtcga acggtaaagc gagtcgtcgg
    41221 cgctgattgc taagcgttga ctggtggatg tgcaatgaac catttcttgc gggattttct
    41281 tttctttcag gcagacatgc tggagtagct tagtcaagac aaataaacga tataatcgtg
    41341 ttcgagttgg tgtgccttgt ggtttcgtca agtgttcgat gtacttagat acttcgtttt
    41401 tcgataatga agacaaatca agtgagaggt caaagtaaaa gacagaatca actggaagtt
    41461 tcgcttcttg aatcaaatcc tcatagctga taatttgttc tttaagggaa ctggcggttt
    41521 caagtatcat ctgcgtgatc tcaaaagatg caggtaattc gctgattctt tctgcgacag
    41581 gaccaatggc gacagaaaaa ttattttttt gtcccttttc taattcatgg accaacgttt
    41641 gggctacctg ataactggtc tcgatcacat tttcttcaag agaatcaact attaaaaatt
    41701 tgatgaatcg agaggaaaca gcagagaaga tcacttgttg attctcccta aataaaaact
    41761 tcaaataatc actgagatga gcgtaatctt caaagtctgt actgacttgg tttgctgcta
    41821 ataatacggt catttttttc cctgctaaag agcgattgaa agattcagca agtttcaatg
    41881 tttcactgat cgtaagtgag cctttgaaca aaccgttcaa gaaatgattt tttttcaatt
    41941 cgaaaacaag atcagaagaa gtgtgcgttt ctttttgctg caaatctaaa gcagttactg
    42001 ctttttctat tgcttgtttc aattcgctac ttttaatcgg tttaagcaga taatcatctg
    42061 cctgtacctg gattgctcct ttcatataat cgaaatcgtc gaatccacta ataaatatga
    42121 gacgagtcca aggaagtagt ttccttgctt cttttgaaaa agtcaacccg tccatgaaag
    42181 gcatttggat atcagtcaga atgatgtcgg gctgtaagtc gataattgaa gacagtgcca
    42241 tctcaccatc tccagcttcg ccgacataag tgattggata ataagaacca aggacagtta
    42301 tttgttcccg caagttattg cgaatgaggt attcgtcttc gatgataaaa actttataca
    42361 tgtttgtttc ctccaattgt tttgggagat agagggatca tcagtgtgac agttgttcct
    42421 tctcggtatt tgctgtcaat cgtgataggt ttttgatcat ttccgtaata aagaaggaga
    42481 cgcttgttta cgttgtaaag tccgtagccg atactgaaat ctgaatcgat ccctttggct
    42541 aactctttac gtatttctgc cagtttttct gcagggatgc caatcccgtt gtctataact
    42601 ttgaattgga tcatctcatc aattttgcat gtggtaatac gaataaatcc tttgtgacgg
    42661 acgtacttcg ttccatggta tacagcattt tcaatcaatg gctgcaagat catttttaaa
    42721 atagaaacag gaaaaagtgt ttctggtata tcgatcttat agtcaagcat atggccgtat
    42781 cttattttta agatgactag ataatcattg atatggctaa tttctttttc aagaggaatc
    42841 cagtcttgtc ctttgcttaa agacgtacga aaaaagccgg aaagtgcatg ggtcatagtc
    42901 agagcttctt caaagcagtc ttgttcgatc aaagaaataa tggcatccaa actgttataa
    42961 ataaaatggg gagtaatctg agcttgcaat acacgaactt cactttgtgc taaatggtat
    43021 tgtttcaaag cgttctcccg taaagactgg tttagatctt ccgccatttt attcatgcta
    43081 gcggtaagtg tttgtaattc cagtgtttcc ggcagggtta aacgaaagcc aaggttccct
    43141 gaagaaagtt gttctgacat ctcgatcagc tgattgatcg gttcttggac ctttctctct
    43201 aaaaagcgac gattcttttt cgcatagaaa aaaatggtac taagaactcc aagttccact
    43261 attgttaata gaatgagcga gcggacaagt gtcgtatttt ttttgcttgc taagtcgatc
    43321 tccacacgaa caaaatcttg taagatatct gacagcagtt gagtgacaga atctacctga
    43381 ttgatgatct cttcattggt atccataaaa tcttttgcca agatattatt gatcagctcg
    43441 ttttgataat cttccagtgt atcgatcgta cgtagcgata catctaacgt actaatttct
    43501 ttaagtgtat ttgtattatt tttgatctct cgaatatcat tcctaagttc ttctaggata
    43561 ttttcctcat tgaactcatc tacggttact tggccagaaa tcaagtccca catactttcc
    43621 aaaacttttt gatcaacctt caaagcaatt gcatctgctt tttggatatt tgcgatcgtc
    43681 tgttgataaa tcaaaagctg ttgcgaatat aacagtatgc tcagtagcaa agggataaca
    43741 gcaaatagaa gcatggcttt gtttgcttgg gcaaaaatct gttttatgct taaatttttt
    43801 gtcatgatac ttctccagtc aataatttct ggttgggatg ttagctatat tctgctggga
    43861 aaagacagtc tcggaaataa aaatatcttt aggtaatgtt tttcctgttt gaatatttcc
    43921 aaaataacga gtaacggtat tggctacata ccagccgaca tcaggtttac actcgactac
    43981 acaattgacg attcctgagc gtagcttctc gatcatatct tcttgtccat caatagttac
    44041 aatgatcaaa tcttctccag gtttgattga tgtttctttt atcgcagcta aagcaccgtg
    44101 agtcatttca tcactatggc tgtataatac atcgatttcg gataaatcat ttgtttctaa
    44161 atatcgtttc atctggtctt ttcctttcat ccgaataaaa tcaccgacaa ttcggtgaac
    44221 aatagtcatc ggaggtttat ggtcgatggt tccatctttt tttagggttg gtttacgatt
    44281 gattgattcc aaaaatcctt cggagcgtag cttggtcggt gtggagttct ctgaaccagc
    44341 aagttctagg attctgattt cctgtttctt tgaatttgtg aagtgattgc tgacaaataa
    44401 acccgcccga tttccttctg ctttgaaact ggggccaatg tgggtgacga aaagctcggg
    44461 atcattcgtt tgaatatgtc tgtcgacaag tatgacaggg atccctgctc gctttgcttc
    44521 ttttaataca gagtcccacc cggattcttg caaaggagta aaaatgatca tatccacttt
    44581 ataggcaatg aacgtccgta tatcttggat ttgccgttcc tgattcatgt agccatttcg
    44641 gtagagaact tggtaatctt ctttttcaag cgcagtgata attgattcag tatgcttttt
    44701 ccgccagcta ctctccgttc ctgattgcga aaaaccaacg actagtgggt caggtgcttc
    44761 ctttgtatta ggtgtacacc ccatcatttg gtaagcgatt acaacaaggg ctaaaaaaaa
    44821 taaaacacgt ttcactttaa atcactccat ctggatttgt tagtactatc ttatcagata
    44881 aaagggaaaa tcaaagtcaa aaggaatcaa tcgaaaaaaa tccaagaaac ttaaaaaaat
    44941 ccaagacaaa aaaagtacac ctaaaaaatt taaagtaaat cccataaaaa aatcaatgtt
    45001 aacgctttct ttattagcta tactcggtgt atcaattgaa atgggggata aaaaatgaaa
    45061 aacaaattta gaaagattgt tgggactatc gctattttga ccgcaagcat tctattaagt
    45121 gcgtgtggca attcaggatc tgcagatgat agtacggggt atgtaggaat cgctatgccg
    45181 accaaatcag cagaaagatg gatcgctgat gggaacaaca tggtctcgga attagaaaaa
    45241 ctgggttata aaacagatct tcaatatgga gaagataaag tagaaaatca agtagcacaa
    45301 atagaaaata tgattacaaa aggggtagat acacttgtga ttgcttctat cgatggttcg
    45361 gctttaactg atgtgttagc taaagcaaaa gaagcagata tcaaggtgat cgcctatgat
    45421 cgtttactga tgaattcaga aaatgtcgat tattacgcga cttttgataa ttttggagta
    45481 ggtgtatcgc aagcagctta tattgaagag cacttaggat tgaaagaagg aaaaggacca
    45541 ttcacgattg aattatttgg tggctcgcct gacgacaaca acgcactaat caattacaac
    45601 ggagtgatgt ctgttttaca accatatatg gacaacggtc agttggtcgt gccatctgga
    45661 cagacgagtt tcagtcaaat cgctacgctt cgctgggatg gttctacggc gcaagcaagg
    45721 atggataatc tgttaagcgc aaattatact gaccaaacat tggatgctgt tttgtcgcca
    45781 tatgatccaa taagtttagg aatcatttcg tcattaaaag gcgtggggta tgggagtgaa
    45841 agtaaacctt tacctgtgat tactggacaa gatgcgacag ttgctggcgt taaatcgatc
    45901 attgccgggg aacaaacaca aacgatcttt aaagacacac gtatcttagc aaaaaatacg
    45961 attgaaatga tcaaagcaat cagtgatgga gaagaggttc cggtcaatga tactgaaact
    46021 tatgataatg gggtgaaaac tgtccctacg tatttagcaa atacagtatc tgtcgataaa
    46081 gataattatc aagcagagct gatcgacacc gattattata aagaatccga tctgaaaaat
    46141 taagaggaac caaacaagga actaaagaga tctaagtcag agagaggata agaattatgg
    46201 cggattgtat tttaaaaatg gcagatatca ccaaaaaatt ttctggaatc cgagcgttag
    46261 attgcgtgaa tctgatgatt gaacgtgggg aaatccatgc attgtgcgga gaaaacggag
    46321 cgggaaaatc aacattgatg aatgtcttga gcggcttgta tccatatggc tcctatgacg
    46381 gggaaatctt ttatgatgga aagctgtgtc aatttaaaga tttgaaagat agtgaagaaa
    46441 aaggcatcgt catcattcat caagaattag cactaagtcc ttatctttca ataaaagaga
    46501 atatttttct cggaaatgaa caagcagaaa gaggcgtgat tgattgggaa ctgacagaaa
    46561 agaaaacata tgaactgctg aataaagtcg gtttgtctat cgacccgaat cttctagtat
    46621 cccagattgg cgtagggcaa cagcaactag ttgaaatagc taaagcatta tcaaaatccg
    46681 tccgtctgtt gattttggat gagcctaccg ctgcattgaa tgaagaagaa agcgcgaatt
    46741 tgctgagatt gatccgagag ttgaaagagc aaggtgtaac ctccatcatt atttcacata
    46801 agctgaatga aatcgtggat atcgcagatc gaatcaccat tttacgggat ggacagacga
    46861 ttgagacact agaaaatgaa atgatcagcg aagagcatat tattcgcgga atggtgggca
    46921 gagatttagt tgatcgttat cctgaaagaa aaccggatat tggagaagtt tattttaaag
    46981 tagaagactg gacggtctat caccctcttg atcacgagcg aatcataaac gaccacatca
    47041 acttgcattt gaaaaaagga gagattgtag gaatagctgg actgatggga gcgggcagaa
    47101 ctgaattcgc tatgagtcta tttggacatt cttatggaag caagatatcc ggacgtatat
    47161 taaaggaagg ggcagagata tcagttaaga ccgttccttc agccattgca aacggactcg
    47221 cttatgtctc ggaggaccga aaatctttag gactgaatct gctgatggat attcgggaaa
    47281 acgtgacgct gagcagtttg gataaaataa gtcaaaaagg agtattagat aaagaaaaag
    47341 aagtaactga ggcagaaaat ttccggaaaa agatgcgtat aaaaacaaac tccatccatc
    47401 aaattgtcag tagtcttagt ggtgggaatc aacaaaaagt cgttttatcc aagtggctga
    47461 tgacacaacc cgatattctt tttttggatg agccaacccg tgggatagat gttggggcaa
    47521 aatatgagat ctacacgatt atcgaagaaa tggcagcaaa tggcaaagct gtctgtctta
    47581 tctcttctga acttcctgaa atattaggga tgtgtgatcg aatctatacg atgaacgaag
    47641 gacgtattac aggagaagtc tcgcgagaag atgcagatca ggaagtcttg atgaaattaa
    47701 tgacgaaaga agaggtgggt taagttggaa caggcaaaaa atcttacgga taaaaaagag
    47761 aaaaaactaa atttgaaaag tagagcagct gatctttttg gtcgctacag catggtgatc
    47821 attttagcgg gactacttat tgcgtttcaa ttgatgacgg atggtatttt ctggcgtcca
    47881 ttgaatataa ctaaccttgt tctgcaaaat agccatatat tagtactagc tgcagggatg
    47941 ttattagttg tgctcttagg tcatgtggat ttgtcggtag ggtcagtgat ggcgtttgtt
    48001 ggtgcaattg cgggcatgat gatggtcaat cgccaaatga acccgtggat gacagttatc
    48061 gcatgtcttg cagtaggcgg gctgatcggc gcatggcaag gtttttgggt agcttatgca
    48121 gggataccgg cgtttatcgt gactttagca ggattgctga tgtttcgtgg actgacacaa
    48181 gttgttctag gaggccaatc tctagcacct tttccagctg ttttccaaaa aatgtctacg
    48241 ggttatttac cagacttaag cgaaggaagc agccttcact tcttgacatt gattttagga
    48301 atgatcatca cgatcgtgtt agttgttggt caatggcgaa caagaaatcg tcggaaaaat
    48361 catttatttg aagtggaatc tccaacagct ttcttggtaa aggcggtatt tacagcagtc
    48421 gttgtactag gaataactta tatctttgcc tcttatcaag ggtatccgat tattttgatc
    48481 attcttggtt tgatcgttgc agcatatggg tttttgacaa ataaaacagt agcaggtcga
    48541 cagatttatg cgacgggcgg aaatcgaaaa gcggctgaac tatcagggat caaaacaaag
    48601 cgaatcacgt tctgggtatt cgtcaacatg ggagtcatgg cagctttagc tggattagtt
    48661 ttagctgctc gattgaatgc ggcaacacct caagcaggta catcgatgga actggatgca
    48721 atggcggcag tatattttgg tggtgcttcg acttccggcg gcattggaac aatcatgggt
    48781 gcgattgtcg gtggcttggt catgggtgta ttgaacaatg gcatgtcgat tttaggcgtc
    48841 ggggtagact ggcagcaggc aatcaaagga ttgatcttgc ttttagccgt tgtgctagac
    48901 ttgtataata agaaaaaacg aacaacgtag gagaacgccg gttattcaga aaaaagactg
    48961 tgacaagaca tttgtcacag tctttttttc gctaaaagcg aacattcatt gtttcgtttg
    49021 tatagactaa aaataatata tgttttttta ccattcgtat aaattctctt tttgctcttg
    49081 atttttttgc ttaattgagt taaattacat agggcgctaa aaaaagcctt gattaaatta
    49141 ataatgttcg tgttttgctg gatgtgaaca tcaggaggat aatgtaatga aagtatttga
    49201 ttacgaagat attcaattaa ttcctaataa atgtatcgta aatagccgtt ctgaatgtga
    49261 tacaacggtc acattaggta aacatacatt caaaatgcca gtagtgcctg ccaacatgca
    49321 gacgattatt gatgaaacaa tcgcagaatt cttagcggaa aatggttatt tctatatcat
    49381 gcatcggttt gatgaagcag ctcgaattcc gtttatcaaa aaaatgaaaa agcgtggatt
    49441 gattacctcg atcagtgttg gcgtcaagaa agaggaatat tcctttatag agaagttggc
    49501 agaagaatcg ctaaatcctg attatatcac tatcgacatc gcgcatggac atgctaactc
    49561 agttattgat atgattcagc atattaaaaa atatttgcct gaaacttttg tgattgccgg
    49621 taatgttggt acaccggaag ccgtccgtga attggaaaat gcgggcgcag atgcaacaaa
    49681 agtcgggatt ggtccaggaa aagtatgtat tacaaaaatc aagacaggct ttgggactgg
    49741 aggctggcaa ctggcagctc ttagatggtg tgcgaaagca gctcgcaagc cgatcatcgc
    49801 tgacggtggg atcagaacac atggcgatat tgcaaaatct gtccgttttg gtgcgacaat
    49861 ggtcatgatt ggttcattgt ttgccggtca cgaggaatct cctggcgaaa caaaagtcga
    49921 aaatggaatc gtgtataaag aatactttgg ttctgcttca gaattccaaa aaggcgaaaa
    49981 acgaaatgtt gaaggaaaga aaatctggat ccaacacaaa ggatctttga aagatacact
    50041 agtggaaatg caacaagacc ttcaatcatc tatttcttat gctggaggaa gagatctgga
    50101 agccattcga aaagttgact atgtcatcgt gaaaaattcg atttttaatg gagacacaat
    50161 ctaaaaaata aataaaatat taggatgttg tgaaaaagtt gtcctgcatt aagtaataag
    50221 aacagccaaa caaaaatagt tctttatatg ttttgtttgg ctggaattat tatcgcagat
    50281 acaagctttt gaacatcatt attcagaata agggactgtg ataagatttt tgtcacagtc
    50341 ccttatgttt tgcaaaaaaa gtttttcttt tttctcgtaa attcggtaaa atcaaaagaa
    50401 aaaatagaca atagaaaaga gaagcttatg tgggaaaaag tagagaaaaa acaaggaccg
    50461 atttatcgtc aaattatgga acagattatg agagaaatcg aaaacggaag gatcaatcct
    50521 ggaagtcaac ttgaatcaga acgaaaacta gggcaacttt ttggtgtgaa tcgttccacc
    50581 gttgtccatg cattggaaga gcttagggag cttggggtac taacgagcaa acgtggcagc
    50641 ggatggtttg ttaatcagac tgaatggggg aaattcgctg ttccaagaat cgattggcgg
    50701 caaatgatct ctcctcgtta tgagcagacg gactggtatg agcaaaaaat aagagaagca
    50761 aagcagatcc aaaaaacatc gtttcttgat ttatacgcta gcgagatgcc agatgagctt
    50821 ttgccgaatt ttgagtttcc ttcttattct cttgaagaaa tcttagcgga agaaaaagaa
    50881 atggatcttt taggctatac tccgttacgt aacaaaatca aacggtattt ggaaagtaaa
    50941 tttgaattgg cattttcccc caaccagctt cttgtgactg gtggcggtca gcaagcaatc
    51001 tttttgattt tacaaacgat tctttcagct ggagagggga tagctgtaga gtcaccttct
    51061 tttttttacc gattacctct tttcaaagct tcaggaacgc gtttatttgg gataccgatg
    51121 gatgaagaag ggatcgactt agaaaaactg aaagaatcga tccataaaaa taaattgaaa
    51181 gcagtgctta tcaacccgaa ttttcaaaac cctacaggaa aagtgatgag tcaaaaacga
    51241 cgagaaaagc tagtagaatt gtgtcgacag tatcggcttc caattattga agacgatgta
    51301 tttacggatc tttcatttct aaaccaagaa gaagtccttc ctatacgaac gattgatccg
    51361 gataatgtgt tatacgtcgg ttcgttatct agggttttag gaaaaacaac gaaaatcggt
    51421 tgggtgatag gacctgagac ttttatctcg caactagctc aagcgcaaga aatgatggag
    51481 ttttcgatga atatccttac acaaatcaca gtggctaatg tatttaatga agcaattgat
    51541 ttgaaaatgc aagatgtaag aaaaaagttg aaagaaaaaa gccgactgat aagcgcttgg
    51601 ggagattcac aatcgttttt caagcttcat tcaattttag gtggttacta tgcctggatt
    51661 acttgggatg ggaaaaaact agaccccgaa ctagcagaaa aagtagtaga tatgggtctt
    51721 ggaattgcac caagtctact ttttgggcaa gatataaatg gaatcagaat caattacagt
    51781 aggctggatg aaaaccaaat accgttgttt tattcaaaga tgaaaattct agaaaagtgg
    51841 ttaacagaat aatttcacaa agtaaataga ttaaagaata taacagcttg gatttaaatt
    51901 tcaagctgtt tctttttttt cggaaaaaga atacgatata aagaaactaa gaaaaaacca
    51961 ttatttgtac gtccgttcac gatgtgtaaa taaaataaat gtttgcaaca aaactgtata
    52021 acaccaacgt ttttaaatag aaacagatgg ttgtaagttt gattagaaaa tagaaaaaat
    52081 gcagatgaaa tataaaacgc tttccttatt gtgattttat tcactaatgc tgttaatatg
    52141 cggattggca taatttcctt tcatcgtgaa aatttgtgct tttagcttgt atttctcata
    52201 aatccatgat aatttattaa tgaagacggt taaatagtga tacagtttta ttcactgttt
    52261 caatcgcaga atgaagagat tttcttatag atgagagagg aatgtgtgac aaatggcaaa
    52321 caaaaaagca ccgatcgact tccaagcact gctagatgaa gtcaatgcag atttcccagt
    52381 atatcaagca cttgatcaag atggaaacgt agttaacaaa gatttagtac ctgatttatc
    52441 cgatgatgaa ctcgttgaat taatgactca tatggtatgg tctcgtgtat tagaccaacg
    52501 ttcaacagcg ctgaaccgcc aaggacgcct aggctttttt gcaccaactg ctggacaaga
    52561 ggcaagtcag ctggctagtg cttacgcatt tgataaagaa gatgttcttc ttccaggtta
    52621 tcgggatgta cctcaactag taaaacatgg tttaccttta tctcaagctt ttttatggtc
    52681 tcgaggacat gctgcaggta attcttatcc ggaagaattg aaagctctac caccacaaat
    52741 tatcatcggt gcacaatatg tacaagcagc cggtgttgca ttaggtttga agaaacgaaa
    52801 caagaaaaat gtcgtcttca cttatactgg tgatggcggt tcatcacaag gtgattttta
    52861 cgaagcaatc aatttcgctg gcgcttacca tgcaaatgcc gtattttata tccaaaacaa
    52921 cgggtatgcg atctctacac ctcgtgaaaa acaaactgca gcaaaaacac ttgcacaaaa
    52981 agctgtcgca gctgggattc ctggtattca agtcgatgga atggatccgc ttgcagtata
    53041 tactgtatct aaaatggcac gggaatgggc gatcagtgga aatggaccag tcctaatcga
    53101 aacactgact tatcgttatg gaccacatac actatctggt gacgatccaa cccgctaccg
    53161 tacaaaagac acagatgacg attggcagaa aaaagatcca ttgatccgct tccgtaaata
    53221 tttgacggaa aaaggacttt ggtctgaaga aaaagaagaa caagtcatcg aagcaactaa
    53281 agaagaaatc aaagcagcta ttgctgaagc cgacaaagta ccaaaacaaa aggtttcaga
    53341 tttcttgaaa aacatgttcg aagtatctcc acaatcaatc aaagaacaaa ttgcaattta
    53401 tgaagcgaag gagtcgaaat aatcatggca caaaaaacaa tgatccaagc aatcacagat
    53461 gccttagcac ttgaactaga aaatgacgag aatgtcgttg tttttggtga agatgttggg
    53521 aaaaacggag gagttttccg ggcaactgaa ggattgcagg aaaagttcgg agaagaccga
    53581 gtattcgata ctcctttagc tgaatctgga atcgcaggat tgagtttcgg tcttgcgtta
    53641 gaaggatttc gtccagttcc tgaaatccaa ttctttggtt ttattttcga agcaatggac
    53701 gaagtagtag ctcaaatggc tcgtacaaga tatcgaatga gcggcactag aaatctaccc
    53761 atcacaattc gttcgccatt tggtggcggt gttcatacac cagaattgca ttcggataat
    53821 ttagaaggtt tgatcgctca gtctcctggt attcgagtag tgattccttc caacccttat
    53881 gatgcaaaag gactattgat ttcttctatt agaagtaacg atccggttgt tttcctagaa
    53941 cacatgaaac tatatcgctc attccgagaa gaagtgccgg atgaagctta cgaagttcct
    54001 ttggataaag cagcagttac tcgtgaggga acagatgtat ctattatcac atacggagca
    54061 atggtgcgtg aagcaatcaa agcagcagac aatcttgcaa aagaaaatat atctgttgaa
    54121 atcattgatc ttcgtacagt tgcgccatta gatgtagaaa cgatcattca atccgtggaa
    54181 aaaactggtc gcgtagttgt tgtccaagaa gcacaacgac aagcgggcgt tgccgcgcaa
    54241 gtagtttctg agatctcaga acgcgctatc ctttcattag aagccccaat cggacgagtt
    54301 tctgcacctg atacagtctt cccatttgga caagcagaaa atgtctggtt gccaaatgca
    54361 aaagatatcg aagacaaagt aaaagaaatc gcggaatttt aagaaaagaa gggacgaaac
    54421 aaagtcatgg cttatcaatt taaatt
//
LOCUS       DACBZK010000010        50647 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.010, whole genome shotgun sequence.
ACCESSION   DACBZK010000010 DACBZK010000000
VERSION     DACBZK010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50647
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.010"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            83..970
                     /locus_tag="IVD66_000670"
     CDS             83..970
                     /locus_tag="IVD66_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP6144915.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1110..2036
                     /gene="cysK"
                     /locus_tag="IVD66_000671"
     CDS             1110..2036
                     /gene="cysK"
                     /locus_tag="IVD66_000671"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HAP6144916.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2272..2718
                     /locus_tag="IVD66_000672"
     CDS             2272..2718
                     /locus_tag="IVD66_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAP6144917.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2991..4343
                     /locus_tag="IVD66_000673"
     CDS             2991..4343
                     /locus_tag="IVD66_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase"
                     /protein_id="HAP6144918.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4514..4801
                     /locus_tag="IVD66_000674"
     CDS             4514..4801
                     /locus_tag="IVD66_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144919.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            5027..5470
                     /locus_tag="IVD66_000675"
     CDS             5027..5470
                     /locus_tag="IVD66_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP6144920.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5476..6660)
                     /locus_tag="IVD66_000676"
     CDS             complement(5476..6660)
                     /locus_tag="IVD66_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HAP6144921.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6928..7626
                     /locus_tag="IVD66_000677"
     CDS             6928..7626
                     /locus_tag="IVD66_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HAP6144922.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7633..8310
                     /gene="nth"
                     /locus_tag="IVD66_000678"
     CDS             7633..8310
                     /gene="nth"
                     /locus_tag="IVD66_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HAP6144923.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8436..8969)
                     /locus_tag="IVD66_000679"
     CDS             complement(8436..8969)
                     /locus_tag="IVD66_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144924.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9266..11647)
                     /locus_tag="IVD66_000680"
     CDS             complement(9266..11647)
                     /locus_tag="IVD66_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAP6144925.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11637..12284)
                     /gene="recU"
                     /locus_tag="IVD66_000681"
     CDS             complement(11637..12284)
                     /gene="recU"
                     /locus_tag="IVD66_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HAP6144926.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12348..12887
                     /locus_tag="IVD66_000682"
     CDS             12348..12887
                     /locus_tag="IVD66_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HAP6144927.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12977..13396
                     /gene="gpsB"
                     /locus_tag="IVD66_000683"
     CDS             12977..13396
                     /gene="gpsB"
                     /locus_tag="IVD66_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HAP6144928.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13418..13785
                     /gene="rnpB"
                     /locus_tag="IVD66_000684"
     ncRNA           13418..13785
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="IVD66_000684"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13994..15160
                     /locus_tag="IVD66_000685"
     CDS             13994..15160
                     /locus_tag="IVD66_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HAP6144929.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15206..16702
                     /locus_tag="IVD66_000686"
     CDS             15206..16702
                     /locus_tag="IVD66_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HAP6144930.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16783..17466
                     /locus_tag="IVD66_000687"
     CDS             16783..17466
                     /locus_tag="IVD66_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP6144931.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            18111..19301
                     /locus_tag="IVD66_000688"
     CDS             18111..19301
                     /locus_tag="IVD66_000688"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HAP6144932.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19403..20356
                     /locus_tag="IVD66_000689"
     CDS             19403..20356
                     /locus_tag="IVD66_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HAP6144933.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20425..21774
                     /locus_tag="IVD66_000690"
     CDS             20425..21774
                     /locus_tag="IVD66_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6144934.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21957..22280)
                     /locus_tag="IVD66_000691"
     CDS             complement(21957..22280)
                     /locus_tag="IVD66_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144935.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22409..23572
                     /locus_tag="IVD66_000692"
     CDS             22409..23572
                     /locus_tag="IVD66_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144936.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23642..24991
                     /locus_tag="IVD66_000693"
     CDS             23642..24991
                     /locus_tag="IVD66_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP6144937.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(25036..25467)
                     /locus_tag="IVD66_000694"
     CDS             complement(25036..25467)
                     /locus_tag="IVD66_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6144938.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            25855..28497
                     /gene="alaS"
                     /locus_tag="IVD66_000695"
     CDS             25855..28497
                     /gene="alaS"
                     /locus_tag="IVD66_000695"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HAP6144939.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28697..29293
                     /locus_tag="IVD66_000696"
     CDS             28697..29293
                     /locus_tag="IVD66_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP6144940.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29415..30563
                     /locus_tag="IVD66_000697"
     CDS             29415..30563
                     /locus_tag="IVD66_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAP6144941.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30601..31014)
                     /locus_tag="IVD66_000698"
     CDS             complement(30601..31014)
                     /locus_tag="IVD66_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HAP6144942.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            31093..31524
                     /locus_tag="IVD66_000699"
     CDS             31093..31524
                     /locus_tag="IVD66_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HAP6144943.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31623..31856)
                     /locus_tag="IVD66_000700"
     CDS             complement(31623..31856)
                     /locus_tag="IVD66_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HAP6144944.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHQ"
     gene            32039..33709
                     /locus_tag="IVD66_000701"
     CDS             32039..33709
                     /locus_tag="IVD66_000701"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HAP6144945.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33856..34242
                     /locus_tag="IVD66_000702"
     CDS             33856..34242
                     /locus_tag="IVD66_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144946.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34229..34927
                     /locus_tag="IVD66_000703"
     CDS             34229..34927
                     /locus_tag="IVD66_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP6144947.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34932..35396
                     /locus_tag="IVD66_000704"
     CDS             34932..35396
                     /locus_tag="IVD66_000704"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HAP6144948.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35393..36304
                     /locus_tag="IVD66_000705"
     CDS             35393..36304
                     /locus_tag="IVD66_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAP6144949.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36539..37078
                     /gene="pyrR"
                     /locus_tag="IVD66_000706"
     CDS             36539..37078
                     /gene="pyrR"
                     /locus_tag="IVD66_000706"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015694870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HAP6144950.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            37092..38375
                     /locus_tag="IVD66_000707"
     CDS             37092..38375
                     /locus_tag="IVD66_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HAP6144951.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38388..39314
                     /locus_tag="IVD66_000708"
     CDS             38388..39314
                     /locus_tag="IVD66_000708"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HAP6144952.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39333..40613
                     /locus_tag="IVD66_000709"
     CDS             39333..40613
                     /locus_tag="IVD66_000709"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HAP6144953.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40618..41694
                     /gene="carA"
                     /locus_tag="IVD66_000710"
     CDS             40618..41694
                     /gene="carA"
                     /locus_tag="IVD66_000710"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HAP6144954.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41699..44884
                     /gene="carB"
                     /locus_tag="IVD66_000711"
     CDS             41699..44884
                     /gene="carB"
                     /locus_tag="IVD66_000711"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAP6144955.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44938..45714
                     /locus_tag="IVD66_000712"
     CDS             44938..45714
                     /locus_tag="IVD66_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HAP6144956.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45711..46643
                     /locus_tag="IVD66_000713"
     CDS             45711..46643
                     /locus_tag="IVD66_000713"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HAP6144957.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46640..47356
                     /gene="pyrF"
                     /locus_tag="IVD66_000714"
     CDS             46640..47356
                     /gene="pyrF"
                     /locus_tag="IVD66_000714"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HAP6144958.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47363..47992
                     /locus_tag="IVD66_000715"
     CDS             47363..47992
                     /locus_tag="IVD66_000715"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HAP6144959.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47980..48294
                     /locus_tag="IVD66_000716"
     CDS             47980..48294
                     /locus_tag="IVD66_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144960.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48332..48973
                     /locus_tag="IVD66_000717"
     CDS             48332..48973
                     /locus_tag="IVD66_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP6144961.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            49004..49708
                     /locus_tag="IVD66_000718"
     CDS             49004..49708
                     /locus_tag="IVD66_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HAP6144962.1"
                     /translation="MKKNMDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKG
                     EETKIEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSE
                     HIINGKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVN
                     PDVFFPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPI
                     QPLNGREIYYFEEFEQ"
     gene            49705..50607
                     /locus_tag="IVD66_000719"
     CDS             49705..50607
                     /locus_tag="IVD66_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP6144963.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
BASE COUNT        16689 a         8805 c        10907 g        14246 t
ORIGIN      
        1 ttaaaagtat aatttaatta attaagtttg ttttaagaag agaacttttt attaagtttt
       61 tttattttga ggaggaattt gaatgcaaga gctgaagacc cgcagtgccc ggcaccatag
      121 acctaaaaga aaaatggtga tcaataaaaa agcgattgct cctttaattg gaacgagtct
      181 tttagttggg ccgatgatgg ttacagcggt accgcaacat gttcatgcag atgaacaagg
      241 atctcaaaca gtcgctgatc ctcaagcgtt tatcgatcaa atcggctggt ctgcgtcaga
      301 agttgctgca agtaatgact tgtatgcttc agtcatgatc gctcaagcgt tgttggaaag
      361 tgcatatggc acttccggat tagctagtgc gccaaattat aatctattcg gtgtgaaagg
      421 aagctataac ggacaggtcg tttatatggc aaccaaagaa tatgtaaacg gacaatgggt
      481 aacgatgaat gagccattcc gaaaatattc ttcttattgg gaatccttcc aagaccatgc
      541 gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg gcgtgtggaa
      601 aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt atgctaccga
      661 tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa cccgttttga
      721 tacgccatca acaggttcgg ctacaacaac cacaagtaca acaacaacga ctactacgac
      781 gacttcaacg tcatcatctt caacaacaga tgtaaataca aataatggtc agacatatac
      841 agtcgtgtca ggtgatacgc tatgggatat tgcacaaaaa tttggcatgt ctgttgatga
      901 tctaatggcg aaaaatggca tgtctatgtc cagttattct ttattagttg gtcaagaact
      961 aaacgtttga tttagataaa aaggcaaaga aattaccata tatggtatat ctttgtcttt
     1021 tttttgctag tcaaagacga atcactcgcc ataaatgaac agattgtatt atgataagta
     1081 agaagagcaa agacaaggag gaattgaaga tgacagctat ctataactca gtcaccgaat
     1141 tgattggcaa aacgccaatc gtcaaattaa ataaaatcgt accagaagat tcagcagatg
     1201 tttttgtaaa gcttgagttt tttaatccag gaggaagtgt aaaagatcgt attgctttaa
     1261 gtatgataga aaaagcagaa cacgatggtc tactgaaacc aggtgatact atcattgaac
     1321 ctacttctgg aaatacagga atcggattgt cgatggtagg agttgcaaaa ggatataaag
     1381 taatcatcgt gatgcctgag acgatgagta tcgaaagacg tttattgatg aaagggtacg
     1441 gcgcagagtt gattttgact cctggtgcgg atggtatttc tggatcaatc agagaagcag
     1501 aacgtttggc aaaagaaaac ggctactttt taccattaca atttgaaaat gaagcaaatc
     1561 ctcttgtgca tgagaagacg actggtcctg agatacatca agcatttgga gtaaatggct
     1621 tggacgcgtt tgttgcaggt atcggtacag gaggaacgat cactggcgct ggccgagaat
     1681 taaaacgtgt gtatccgaaa atcgaattaa tcggggtaga accagcagaa tctgctattt
     1741 tagaagggaa agaagcggga cctcacaaaa tccaaggaat cggtacaggt tttgttccta
     1801 aaacactgga tacttctgtg tatgataaag tcctttctat tagtggagac gaagcgatgg
     1861 aaacagctag agaagttggg cgaaaagaag ggattttagt aggcatctca tctggcgctg
     1921 caattgctgc cgcgctaaaa gtcgcaaaag aattaggaaa aggcaagaag gtattagctg
     1981 tggttcccga caatggtgaa cgttatttat ctacagccct ttaccaagag atataaggca
     2041 cttggttttt ctccagatag gtttatgtaa aaaactttta aagatgaaaa gaacacacaa
     2101 aaatttatga tgagaaaaat tatttgaata gagacgtaga atagtgaacg cgactgtttt
     2161 acgtcttttt tcattaaaat acaataaaat tgaattttct tttcatgtta agtggatttt
     2221 aaaatgtaaa aatagtatga taagacgaga ataacaacgt ggggtgttta catggaaaat
     2281 aagttagtcg aagaggttat cgaaaagtta aaaaaagaga acattcgaat cacacctcaa
     2341 cggtacgcgg ttttagaata tttgattgaa catcattccc atccaacggc tgatgagatt
     2401 tataaagcac ttgaacatcg gtttccaaat atgagtgttg cgactgttta caataacctt
     2461 cgcttattta cttcgattgg atttgttcaa gaaatgaagt acggcgatgc ttctagccga
     2521 tttgatttca gttcaaagcg tcattatcat gtaatttgtg aaaactgcgg taagattgtt
     2581 gattttcatt acccagggct tgaagatata gaaatggctg caagcagact gactgatttt
     2641 gagattaatg aacatcggtt ggaattgtat ggactctgtc cggattgtaa agagtcagca
     2701 aaaaaggcgc aaatgtaaaa acagtttcta caagtgttat acctaaaaaa agctagctgt
     2761 gtaaaaaaaa cgctagcttt tttatttttt tgtcttttat tcacaatctt agatataaaa
     2821 gtgaatatta ttaaaataag aatcttgtag atattgggtt cttatgcttg aaaaggaatg
     2881 aaactacaaa caaacctttg tgaattcaca agcattaaac tgttgtatcc gttttatttc
     2941 tgttatagta gttttgtcga aggacaaaat gttaatcgga gggaccataa atgaaagtag
     3001 tagtaattgg ctgtactcat gcaggtactg cagctgtaaa aagtatttta aaaaatcatc
     3061 cagaagcaga agtgacagta tatgaaagaa atgacaatat ttctttctta tcttgcggta
     3121 tcgcacttta tgtcggcgga gtagtaaagg acccagcagg cttgttctac tcaaatcctg
     3181 aagaattatc ttcattagga gcaacagtta aaatggaaca cgatgtaaca gacgtcgata
     3241 cagaaaataa aacagtaacg gcaaaagatc tgaaaacagg agaaacagaa acggtttctt
     3301 atgataaatt agtgatgaca actggttcat ggcctattat cccaccgatt agtggaatcg
     3361 atgcgaaaaa tgtactccta tgcaaaaact acaatcaagc aaatgaaatt attgcacaag
     3421 cgaaagaagc aaaacgtgta gtaattgttg gtggtggata tatcggtatt gaattagtag
     3481 aagcttttgt cgaatctgga aaacaagtga cattgattga tggattagat cgcatcttga
     3541 ataaatatct agataaacca ttcacagata tcttagaaaa agaattgaca gaccgcggtg
     3601 ttactcttgc gctaggcgaa aatgttactg aatttatcac agatgaagaa ggaaaagtga
     3661 aacaagtagc tacaccaaca gatacatttg atacagatat ggtcatttta tgtgtgggct
     3721 tccgtccaaa tacaaaactg atcgaaggaa aagtagatac actgccaaac ggggcaatca
     3781 aagtgaatga atacatgcag acaagtaatc cagacatttt tgcagctgga gactctgcag
     3841 tagtcaacta caatccaagt ggcacgcaaa actatattcc tttggcaaca aatgccgttc
     3901 gtcaaggttt gcttgtggga aataacttga cagatcataa aatggcgtat cgtggtactc
     3961 aaggaacttc aggactttac ctatttggct ggacgatcgg ttcgacaggt gtgaccaaag
     4021 aaagcgcaac tttgaacgat ctagaagtcc aagcgactgt atttgaagat aattatcgtc
     4081 cagagttcat gccaactact gaaaaagtaa tgatggagct agtctatgaa aaaggaacga
     4141 atcgtatcgt aggtgctcag ttcatgtcca aatacgacat tacacaatca gcaaatacca
     4201 tgtctttagc tgttcaaaat aaaatgactg tagaagatct cgcactttca gatttcttct
     4261 tccaaccaca ttttgaccgc ccatggaatt acttgaacct acttgcacaa gcagcgctag
     4321 gcgaaatcga aactgcacaa taaagaaaaa gggttgtgac acaattttgt cacgaccctc
     4381 tgtctttttt tgtgaaaagt acaattagtt gtctttcttc gaattttttg tcacaataag
     4441 cagcaaagat aaagctgtta cataaaagaa caagcagctt tatttgattt tgaaaagaaa
     4501 ggtgagaaag aagatgaata aagaatattt tgtccaacaa gatgcatttt tagaagatta
     4561 taaaagtgct tcgaagaaat taacgatcaa tattgatgag ttggcagatc aagtactctc
     4621 tcagttgaat gaaacgcaag aggaatatta cacgatgcca gcaaatgacg ccaaagataa
     4681 tgtttctcat cgttttcctt tcagtagacg catctactca gatgaaaatg acggcacatt
     4741 gaatacagag tacacatatg aaggtcagcc atatgtgcta gaaactgatg atgatcttta
     4801 aagacagttt ttgaaaaggc cgctcatcct taagtgatga caaaaaatca tcacaattac
     4861 cgatgactgt ctctttacta tcttttaatc agaaaaaggg gttatgacaa gctttgtcaa
     4921 cccctttttt tcttggtttc agattgggtt ttcctacaaa atatttttat ctttgttgaa
     4981 taggaaacaa aaaaacaata taatgaaaga aaaagaaggt gtagaaatgg ataaaagaca
     5041 actgctaata gaagaatatc tggatttagc taatgagatt attcatcgta ataaaccaga
     5101 aatggaaaaa gaatttgcag gatttactct aaatgaacta gaagtgattg aacatatcgg
     5161 gaaaatccct gatcctaacg tgacaaaatt agcgaatgct agttacatga ctagaggagc
     5221 catcagtaag ctaacaaaaa aactgatagc tagagggatc ataaacactt atcaaagcga
     5281 agagaataaa aaagaaatct attttcaatt gacgccaatc ggacaaaaaa taaggaatag
     5341 acacgagcaa ctccatcaaa aatgggtaca gcgagatgct actgtatttg aaaatatgtc
     5401 aaaagaagaa tttgacacag tatttcgttt tatcggtcga tacagagaat ttatacgaag
     5461 tagcaaatga agctactatt ttttattgta gtgataatag gcaaaaatca taagcaaaaa
     5521 tccgaatacc gtcggaagaa atggtgctgc agcataaagc tgtcctgcga ttagcgggcc
     5581 gatgacgcgc gatagagatt gtatactttg ggtaccgccc attacaagac cttgctggtt
     5641 atctgagaca gaattggata gttggccatt gaatacagga gtaaaaatag aatcaccgaa
     5701 accataacag ataatcccaa ataaaaacaa aatcggcagt agaagaattc cagataatgt
     5761 gatgaataga taggcgagga tttcactgaa catccctatt cttgtgatct gctgttctga
     5821 aaattttttg agcaatcgag gcataatgaa caattgcgag acagtatcca agattccaat
     5881 caaagagaag cttaaaccaa ccaacccagc cttccactga aaggcgtcaa tcgaaaattg
     5941 agaaaagata gattgaagag agccagctgc caaccaaaca gcaaaacctg ctgtcaataa
     6001 aggaataacg gatgaaatct tgaataattg ttgtaattgg tgaaaaggtc ttacatggga
     6061 gaaacttaaa tctactgaac gtttttttat tggaaggctt tctagcataa atgtgtagcc
     6121 ataaacggca tttaagaaag taaagagtgc tccaataaat ataggaacag aattccccaa
     6181 ctcagctaat agacccccta taataggacc cagcgttgtt cctataccga ctaaagcacc
     6241 catccatcca aaaactttgg ttctttcatt aggttccgtg atgtcggcaa agtaagcata
     6301 taaggtggag atttctcctg ccgtcaatcc ttcaatgata cgaccaagga acaacatcca
     6361 tatcgaattt cctaaaccaa aaagcaaata tccgatactt gatcctaata aactgataat
     6421 aaggatcgga tgacgcccaa aatgatcact taagctaccg agaatggggg cagataagaa
     6481 ggcagctaga gcataaacag acatgagcaa agtgatatag aaagcttgct gatgtatgga
     6541 gtgagaataa ggcagcgtta aaaacggaag tacaggactg acgatagtaa atcctaatcc
     6601 agtgaataag acagagacgt atccaaaaac tttagaatgt ttatttgtga aactgtacat
     6661 gtaaaaactc ctttatgcaa taatgttaac ttggaaacaa aaatagtgta tagtaatttt
     6721 gtttccttgt caacattcta aggaacagcg aaatctactt aatttattta ttccgaaaag
     6781 tgaagatacg catcaaaaac atgaacaaac aaaaatcaag tagacgacat tgtaaatctg
     6841 accgatcagt gaagtaaata gaaaagaaac ctgttcttgc ttcccatgtt ttttttacgt
     6901 atactgtgat tgagcggagg agaaatcatg ttgaatttag aaaattactt aagcgctgga
     6961 caaacagtca tatctaatct tttacttaaa aattatcata ggatcggtct acaatctgaa
     7021 gaatttttat ttgttctaca gttgcatatg gcacagcttg aaggagatac tttccctgat
     7081 ttgcagatga ttgctatgga tatgggaatc aaacaagatc agatttttca aatactggat
     7141 cgtctcgtaa caaatggatt tatcaagata gaaacgacga ttgtcaacgg taaaaaagca
     7201 gatcgatata atctttaccc catctatgat ctattaggtg agtatttaaa aacacaagaa
     7261 aaaaaatacg aagaaaaaac acaagaaaaa gaaatccagt cagtgtatca attatttgaa
     7321 caagaatttg gacgcccgct ttcttcgatc gagttccagc ggatcggaca atggctagaa
     7381 gaagaccatt atcagccgga aattttgaag ctagcactgc gggaagccgt attaaatcag
     7441 gcttatagtt ttaattacgt tgaccgcatt ttgctatcgt gggaaagaaa aaatctacgt
     7501 acaaaacaac aagtggaaga agaccaaaaa cgaagaaaac agcagcttct tcaaagagaa
     7561 gtagaacagt cagctcaaca agaagaattg ccgaaagtct cactgaaaaa ttggttggag
     7621 gagtagcgga atatgttaag caaacaaaaa acaatggaag ctctagaaac gatgtatgga
     7681 atgtttcccg aagcacatgg agaactcaag cacaataatc catttgagtt attgattgca
     7741 gtgatcttaa gtgcccaggc gacagatgta tcagtgaata aagcaacgcc agatttgttt
     7801 gcctcttttc cgacacccga tgcgttagca gaagcttcaa tcgatgaaat cattcttaaa
     7861 ataaaaacga ttggtttgta tcgaaataaa gcaaaaaaca tcaaagcgtg tgcacagcag
     7921 ctgattgaac gtttcgatgg gcaagtgcca acgtcaagag aagaattgat gtctcttcct
     7981 ggtgtaggca gaaagacagc aaatgtcgta ttgggggatg cattcgggat accagcaatc
     8041 gcagtagata cccacgtgga acgtgtctca aaacgcctga ggatctgcaa actagatgct
     8101 acggtcatgg aagtagaaga aacactgatg cggaaagtac cacaagaatt atgggtaaag
     8161 acacatcata cactgatttt ttttggtaga tatcattgca cggcaagaaa tcccaagtgc
     8221 gaggtatgtc ctttgctatc aatatgtcaa gatgggaaaa atcggatgcg tctaaaagaa
     8281 aaggcgctaa aaaagaaacc acgcctgtag acgtggtttc tttaattgca aataaatgta
     8341 tgaattatct tgttattatg gagaaaagct gtttcgttta tcttttttgc atgaaaaagt
     8401 aaatgtacat actcagtagc taggatggta acttattaca atttattgcg ataaaaataa
     8461 aagttgttat ttttattggg aaaatacccg atgtagaaaa taatgccttc caatatacct
     8521 ataaaataag tccagtattc caaaggatta tataaataag tgacgtatct atctaaaggt
     8581 gtaataaaaa tgataagtga taataaaaaa ataccattta taactaaaca taaactaatg
     8641 gatttgggcg gtttcaggct catcagaaaa atatagattc tggtgaacaa caaccataaa
     8701 aaagtgagaa tcattgcatg agagcttctt tccataaatt ttcctttaag agtagtgctt
     8761 aaaagtacag aaaaaataat aaatgcaagg ataggagcaa ttaaagtaaa tttatttaat
     8821 aataaacaaa atttttcagc ttttttattc ttggaataac gaggtattgt tttcgataaa
     8881 aaaagatggt gcagacaaat tatgataatt aagcatacta tcagataact caaaatgaag
     8941 ccttctttca aaaaattatt caaaaccata tattgtattt tttatttgat aataacaatg
     9001 ggattattaa gaagtggcac taaataaaag actagtgtgt atttagccga tttaattata
     9061 aacaagtaaa tggataaagt atatgtaatg ataaaagaaa aatggatttt ctaattttta
     9121 agctaaatgt tagatcacac atgtatatgc tggatagtct tataaaaaat catgtaatac
     9181 agcttggtac atgattttta tttgtagctg ttttttacat agacacaaaa aagaaaccac
     9241 gcttgtagac gtggtttctt ttttactatc tgtttccaga agctgaggtg ctgctggatg
     9301 gtgtatggtc atttgcagca tccgctccgc tagttgctgg ctcactggaa gaagcaggag
     9361 gagcagatga agacggtgtc gagctttctt cggatgaaga agaaggaacc gttgttgaag
     9421 acgctggctc gcttgtttct gctgtcgtgc tttcttttga ggactcagca gttgattcgc
     9481 tttgactagt agagctagag ctttgagtcg ttgtctctgt tgttgagctt ccaggagtct
     9541 ggacatagct ggaagatgga atagttgttg atggtgtaat tgcattcgat ctagctgtat
     9601 attgatcttt gtagtacagt tcaccgccca cacgaattaa tccgcttggc atctcccagt
     9661 ctgtatttgt cacgttagct gaaacatact gcataagctc gcgataaaca tcagaggcta
     9721 cgtgtgacga ttctgaagtg acaggtgtca tttttttatt gtaacctgtc cacacggaaa
     9781 tcgaataatt tggcgtatag cccgcaaata ggatatctgg atacacccca gaagaaatac
     9841 caagttttgc atactcgtca tctgtgtaat tggatgttcc ggtcttaccg gcttgatata
     9901 acccagcgat ttgcgcattc gtaccagttc cttcagtgat cgtatctttt aaaatgtctg
     9961 tgatcatata agctgtttct ggagacatgg ctgtttttcc atctggctca taagtttctt
    10021 ctgttccgtc ttggaagacg attttattaa catattgagg tttgtaataa gtccctccat
    10081 tggcgaaagc cgcataggct gctgccattt ttaaggaaga agctccgtat tttgtcccat
    10141 cttgttcttc cgtattacta gagatcgcat tcgattgatg gatcgtactg tattcgatcc
    10201 caagattttt taagaaagaa gccactttat ctgaaccgac ttcattgaat aatttgactg
    10261 ctggaacatt acgggataag taaagtgctt ggcgtaaagt aatggtgccc atatattgat
    10321 tatcccagtt tcctacagga gtcgaagtcc cttcatagtt atacggtgcg tcagtaatag
    10381 tttttccagt agaatatttc aaatattcaa aagctggtcc gtaatctgtg acaggtttca
    10441 tcgtagaacc aaaatcacgg gaagtattca ctgctaagtt gttgcctaaa gttacgtctt
    10501 ctgcgatgtg acgtccgcca atctgggctt ttactttccc ggtattggtg tcgataaggg
    10561 tggaggcaac ttgcatctcg tcgtctgggt aagagacata ctgatccgtg ttgacgatat
    10621 catatagttt cttttgggcg tccagatcca aattcgtata aatctctaaa ccgtctgtgt
    10681 agacattctt atctgttttt tcttgtactt cattgatgac ttctttgaca taattatcga
    10741 cgatcttagt attgtcatcg gattgagtta gttcttgcag accatccgtt accggtacat
    10801 taacagcttg atcatattct gtttgagaga ttttttcgtt ttgaagcatc gtatacaaaa
    10861 cagtatctcg tcttttcttc gcctgatctg gataaacata aggatcatag gcggaagggg
    10921 cttgaggcat cccagcaagc aatgctgttt gcggtaaaga aagttctgat aatttcttac
    10981 caaagtacat ctcagaagct gtctccatcc cgtacaagcc gtttgacata tacactttat
    11041 ttacgtagta ggtcaagatc tcttgtttcg attttttttg ttccaatctt acagccatcc
    11101 acgcttcttg ggccttgcgt ttcagagtct gatcctcggc actggtggag aagaaggaaa
    11161 gtttgatcaa ttgctgtgtc aaagtacttc cgccttgcag tccgccagag gtaaagttag
    11221 agagggcaga accgatgatc cgaatagggt caaccccgat gtgtttataa aaacggcgat
    11281 cttctaccga cacgatcgca tcttctaatg ttttcggtaa ttcattcgca gaaatttttt
    11341 cacgcttttc tgcgcctaaa tcttcgaata gttcgccatc ttgtgtatat agtttggaag
    11401 atacggtagc gtctaatttt ttatccgtca attcgggcgc atcttttgcg taataccaga
    11461 aaagtcctac acctgctaaa aagaggatac agaaaaatga gagtattcct aaaaggatct
    11521 tgataaataa tcctttttta tgtgttccag aggactttcc agaacctttg ccagaattct
    11581 tcttcacact ctttttagga gtaggctgtt tctgtcgtct agagcttcta gtttgttcat
    11641 ttgccattct tgctttctcc ttcaatagat aatgttgata aatagaagtc aaccgcgtcc
    11701 aaataaggaa tccgcggaga aataccagtt ttgatctcta ttcctagttc ttcgatcaaa
    11761 gataaaggta gtgatttgcg tcctttttcc ttttgggcgt cccagtaagc aatcaaatga
    11821 acactattca aataaaaaca gcgcttcaaa gacgaaaacc ataacaagac aaagcagacc
    11881 ccattttgtt cgaggcatgc tttcatatgt tcgatttgat gggcatggaa gtttttaaag
    11941 ggaaaagatg ttttgttctt ggtttctttt gcttcaaagt ccaagtaaaa gcctcgatag
    12001 acgccattat agtctgtagt tgaggcttgg gtaaagtagg cttccttgat cacagcagca
    12061 cttctcttag gatagtctac tttcacgatt tggatagggg taggcttttt atggataacc
    12121 gccaacccgc gggaaagata atatttatta ctttcattga ttgcttcttc aaagcgcatc
    12181 ccccgattgc cgaattcagt gatctgattt cttttttctt gaattttttc gacgggagag
    12241 gcattcttat aataaggttg gccatttgga tagcgcaata ccatctttaa tcacactcct
    12301 aggccacatt atagcaaaaa agcggataga aagaaaagga atctgagatg gataagtcaa
    12361 aagtaatcta tgtgtctggg tatcgaagtt tcgaactcgg tgtttttaaa gaaaatgatc
    12421 ctaaaatcca agttgttaaa aatgttttaa aaaaagaact ccatcagtta gcagaagaag
    12481 ggctggaatg ggtacttgtc agtgggaatt tgggcgtcga actatgggct gtgcaaatag
    12541 tagcggaatt gaaagaagaa tatccggaac tatctcttgg tattttgtat cctttttctg
    12601 attttggtaa taactggaat gaagggaacc aagaaaaaaa acaattagca gaacaattag
    12661 cagattatgt cgaagctgtt agccatcaac cctaccaatc acctagtcag ctaaagaatc
    12721 acactcgttt tatacttgag catacagtgg gctgtctgct gatctatgat gaagaattcc
    12781 ctggaaaaac gaagtatttt tttgaagatg cacagaatta ccaagcagat catccctacg
    12841 aaattcggct gatcagtatg gacgatcttc aaaattttag tgaataatcg atattgtgtt
    12901 tgatttatca acttttttcc tatacaatga aaaaggtaga aatgttatta cgtaaatgaa
    12961 aactagaggt gtaaatatgg cgaatttggt ttatagtcct aaagacattt tacaacaaga
    13021 attcaaaaca aaaatgcgcg gctatgatcc cgttgaagtt gatgaattct tagacaatat
    13081 catcaaagat tatgaaactt acagcaaaga actccttgct ttacaagaag aaaacgatcg
    13141 attgagtgca aaagtagctc aattatctaa aactcaagga gcagctcaaa cacgcgtgca
    13201 acaaacagag gcaccaaaga gcgcagcagt gaccaatttt gatatcttaa aacgcttgtc
    13261 aaatcttgaa cgtgaagtat ttggtaaaaa gcttgatcaa caagcaagtg cagtcaaacc
    13321 agcacaacct aatccaaata actacacaaa tgcagacaca agcttagatg ataatgaaaa
    13381 aacacgtcaa ttttaatttt tgattaatga atttgcggtt ttcgggtaat cgcggtctga
    13441 cttgatcagg ctgaggaaag tccatgctcg cacaggctgt gatgcctgta gtgttcgtgc
    13501 ttagcgaaac cataagctaa ggtactcttt ggagtaacgg caggaaaaca agctaaggct
    13561 tcggctatgc ttaagtatcc ttgaaagtgc cacagtgacg aagcggctgg ggaaacccat
    13621 ccggtggaac gcggtaaacc cctcgagcga gcaacccaaa caatggtagg ggcgcttttt
    13681 gtctggaaga agaacaggac aaaaaggcag tataactgca gatagatggt taccgctttg
    13741 ttttttctcc ctggaaaagc aaagtacaga acatggctta tagaaaaccg caaacatcag
    13801 ggaattaggt cgtgacaaaa gtaatgcgtt ataagaaaca agaaaaacat ttgaaagcta
    13861 tttttcaata cttcagatga atcgttctta ttacaaaaca aacttttgta tcaccggtta
    13921 ttcggaattt gagtaaaagt gtggggtagg actgatgtcc cacctccttt ttttataaat
    13981 aaggagattg tgtatggaaa aaaacaggaa gttcaacctc gtcgcaactg cggcaagcgg
    14041 gctagaagca ctggttggta aagaattaag agatcttgga atcgaatgcc aagttgagaa
    14101 cggacgtgca cgttttgaag gaacaatgga aacgatcgct acagctaatt tatggttacg
    14161 tacagcagat cgagtaaaaa tcgtggttgg ggaattcgat gcgtatacgt ttgatgaatt
    14221 gtttgaaaac gtaaaagcat tgccttggga agattttctt ccactagatg cagcttttcc
    14281 tgtagctgga aaatcgatca agtcgaaact atatagcaca cctgattgcc aagcgatcac
    14341 aaaaaaagca atcgttgaac gtctccgtac ctattatcac cgtccagctt ctgtaccact
    14401 gacggaaact ggcgcacatt ttcagttgga agtagctttg ctgaaagacc atgtgatggt
    14461 aactctggat acgacaggac caagtttatt caaacgtggt tatcgcttag aaaaaggtgg
    14521 agcaccattg aaagaaaaca tggcagcagc acttattatg ttgacaaatt ggcgaaaaga
    14581 ccgtccattt tatgatcctg tatgtggttc aggtacgctt tgtattgaag cagccttaat
    14641 aggccataat atcgcaccag gattcaatcg tgagtttgct tgcgaatctt gggattggtt
    14701 cagtcaagaa atcatggaaa atgttcgatc agcagccgaa gaaaaagcag attatgatat
    14761 tgaattagat attactggtt cagatatcaa tggacggatg attgaaattg ccaaagccaa
    14821 tgcagaagaa atcggattag gctcttcgat tacctttaag caacaagcag tcaaagactt
    14881 caaaacggat aaagaatacg gggtcatcgt ggctaatccg ccttacggag aacgtctagg
    14941 agaagaagaa actgttcgga aattatataa agaaatgggc gatgtattcc gtccattaaa
    15001 aacatggagt aaatatatct tgactagcga cttagcgttt gaggaatttt acggacaaaa
    15061 agcaaccaaa aaaagaaaat tgtacaatgg tgcattgcgt acggatctat ttcagtattg
    15121 gggaactcgt ccgcctagaa aaaaagagaa agacgaataa tcttactaat tgattcattc
    15181 aattggatgt ttggaggaat agggaatgaa agaaaaagag tttttacaag aagtaaaaga
    15241 aatcaatctt ctacaacaag ctttaggaat cctcgattgg gatacacaaa caggtatgcc
    15301 tgaaaaagct agtgcatacc gaagtgaagt agacagctat ctttacagca tttatttttc
    15361 aaaaaaaatc ggtccaaaaa tcaaagaagc cattcgctat ttttctgaac atccggaaga
    15421 attgtcggaa gttggaactg ccgtttttgc caaagtaaaa gaagagtatg atttggaaca
    15481 tcgcgtaccg gaagatctta tgagaaaata tacagctgcc gtttcttcag cacacggaca
    15541 atggcaaaaa gctagagaaa cacaacaatt ttctgatttt caacacgcat tgaatcaaaa
    15601 tattgaatta acaaaacagt tgatacctta ctggagaaaa gatgaaaaga cgaattatga
    15661 tgttttgctg aatcaatacg aacccgggat gactgtcgaa atccttgata aggtatttga
    15721 tcagcttaaa gaaggaattc tttcgatccg ccgtacgctc caagaaaaag ggactgaacc
    15781 tgaaacagac tttttaaatc ggagaatgac gaaaaaacaa cagaagagat ttgtagtgaa
    15841 agtaatcgaa caacttggtt atgattttag tcgtggtcgt ttagatgaca ctgtccaccc
    15901 atttatgact ggaattaatc cgaatgatgc acgaatcacg acacgatgga acgaaacaga
    15961 tttcaaaatg gctgtttttg gagtgatcca cgaggctggt catggtatgt atgaacaaga
    16021 catcgatgat aaatatgcgt atacaccggt ttatgaaggt acatcaatgg gtatccatga
    16081 atcacaatcg ttgtttaacg agatcattat tggaagtagt cgcagcttct ggaaaaagca
    16141 atatcctttc tttcaagaat gtgcagaagg aacattcgat gatattcctt ttgacaaatt
    16201 ttatcgttca ttgaaccata caaaatcaag tttggttcgt atcgaggcag acagtttgac
    16261 ttaccctctc catatcatca ttcgttatga aatcgaaaaa atgattttca atgaaggggt
    16321 agatgttgct gaactacctg aaatatggaa tcaaaaatat gaagagtatc tgggaatacg
    16381 accaacaaat gatgtggaag gcatcctaca agacgttcat tggtcaggtg caagctttgg
    16441 ttattttccc tcttatgcat tagggtacat gtatgcggca caattacttc attctttgca
    16501 gcaagaaata gatgtggaaa atgttctagc gtcagacgat tattctccaa tcaaaaactg
    16561 gatgtcagag catatccatc aatatggtgc atctagaaaa ccaaatcaat taatcatgga
    16621 tgcaacacat gaaccgctta atccgcaata cctgatcgac tatatgaaag acctgtattt
    16681 taatgtatat caggtaaaat aaaatacaat ttacaaagat agctgaaatt catctaatct
    16741 atagatgttt tcagctattt acttaagaaa gaagtggaac gaatggataa attacaagtg
    16801 atcgctgatt atagtatgga ccaattagcg catgatcaaa caggacatgg gagcgatcat
    16861 accaaaagag ttgtcaagtt agctgaaaaa attttggaga cggaaccgca ggcagaccgc
    16921 tttgtgacgc ttgcagcagc ttacctacat gatacgattg atgataaagt cgttaaaaat
    16981 gagaacgagg caaagcaaca gcttcgtgta ttccttcgct ctttgccaat agtagaggaa
    17041 cagatctcga tgattttttc cattatcgaa aatatgtcct tttctaaaaa tctctctgaa
    17101 gcggccgaac tatctctgga aggtaagatc gttcaagacg ctgatcgtat cgaagcatta
    17161 ggagcaatcg gcattttgcg tactgcttat ttcggcggtg gacatgggca cccgattttt
    17221 gatcctgaac tgtatccgca aacattcaag gacaaagaaa attaccgaaa aggcacgaca
    17281 gtgatcaatc atttttatga aaaactgttc ttgctgtctg ataaaatgaa tactgattac
    17341 ggatatgaag aagccaaacg aagagaaacc ttcatgcgtg aattcttaga agaatttttt
    17401 ctggaatggt ctattgacga tgaaaatttt actccagaca attggatcaa aaataacaaa
    17461 aaatgatgga ggttgtgaca gaagtggtca gctccaagat atttcggatc attttccgta
    17521 aaagttactt ctggaacact gtttaccaag aggtcgtgag cctgccgttc agctccgagt
    17581 cacaaggaac aatttcaaaa aatagcttct cgtgtttgat gaatattgta acttgtgatt
    17641 cggaattggc aggagaacac cgtttattcg gaagaatagg actgtgacaa gacttttgtc
    17701 acagtccttt tttcgaattc aacaagtaaa acttttaaga aatattcaga gagtaaaatt
    17761 aaaaattgct gataaacgaa gatggaaatt ttatgtattt ttattggtct atgcaataaa
    17821 taaattaaat attcagaata caattgattt taacgaaagg gcttctatca atggttgtgt
    17881 tgtatttatc tgcccaggta gagtaaaata gatcattatc taaaaggtaa ttgttcatac
    17941 tatataagtc atttgaaagt aaaaagatac tgtaaataaa aaatgtggtt aaataattct
    18001 cataatcagt gtaagcgtta tcaaaaatat agcatacttg ctttgtagat gaatgacacg
    18061 atatatgttt ggtatgttct gcaagacaga tgaatatgga ggtggagaca atgtcttcca
    18121 aagaactaac aatgtattta gagaaagaat tggatcaact gaaagaaaag gggttataca
    18181 atacgatcga catactagaa agtgaaaatg gtgcttgtat catcgtagac ggaaaaaaga
    18241 tgatcaatct agcatccaac aattatcttg gatttgccaa tcgcgaagaa ttgaaaaaag
    18301 catgtattga agcaaccgaa acttatggtg taggagcagg agcagtccga acgatcaatg
    18361 gttcgctgaa aatccatcag caattagaag aaaaaatcgc agaattcaaa gggacagaag
    18421 cagcaatcgc ctttcaatct ggattcaact gcaatatggg cgctatctct gcagtaatga
    18481 caaaagaaga tgctatctta tcggatgaat taaaccatgc atctattatt gacggttgcc
    18541 gcttatccgg agcaaaaatc atccgaatta aacatcaaga tatgaaagac cttgagaaaa
    18601 aagcaaagga agcgatagaa agtaagaaat ataaaaaaat catgtatatc acagatggtg
    18661 ttttctccat ggatggagac attgcacgat tgccggaaat tattccgatt gttgaaaaat
    18721 atggactgat cacctacgtc gatgatgcgc acggctcagg cgtaactgga aaaggtgcag
    18781 gaaccgtcaa gcattttgga ttaagcgaca aaatcgatat gcaaatgggc acgttatcga
    18841 aagctatagg tgttgttggg ggttatgtag ctggatcgaa aacactaatc gactggttga
    18901 aagctagaag tcggccattc ctattttcta cttcgctaac tccaggtgca gctgcagctg
    18961 cattggcttc gattactttg atgcaagaac atccggaact tgtcgaaaaa gtttgggaaa
    19021 atgctaatta ttttaaagaa gaattgaaaa aagtaggcta taacatcggt atgtctgaaa
    19081 cacctattac tccagtcatt ttgggagacg aaaaagtgac tcagactttc tctaagaagc
    19141 tgatcgaaca tgggatttat gctaaaccaa tcgtttatcc aactgtgcct cttgggacag
    19201 gcaggatcag aaatatgccg actgcggaac atacgaggga aatgcttgat gaagcagtag
    19261 cagtttatca aaaaatagga aaagaaatgg aaattattta actaaattta gttttttcgt
    19321 ctatttaaaa ttagagaaca tgttcacgca tatattgtta atcatctgaa gatagtagta
    19381 aaaaagatca gggaggatca tcatgaaaaa agtattggtg acaggatgtt taggacaaat
    19441 tggttcagag ttgatcacac ggctacgtca agaactaggc agtgaaaatg tcattgcgac
    19501 agatatacgc atgcctgaag tcattgagaa aaacgatatc tttgagatcc tagatgtaat
    19561 ggattacgaa aaaatgcgca gcatagcaga acaatatcaa gtggacacat tgattcattt
    19621 ggctgctctt ttgtcagctg ttgcagaagc aaaaccacaa ttagcctgga atttgaacgt
    19681 gactgggctg gtcaatgcat tggaagtcgc tagagaattc cagctgaaat tttttacgcc
    19741 aagttcaatc ggcgcgtttg gtccaaatac tccaaaagat cataccccac aagatactct
    19801 tcagcgtcct acaaccatgt atggggtaac gaaggtagct ggagaactac tatgtgatta
    19861 ttattatgtg aaatatggcg tagatactcg tggtgtccgt ttccctggat tgatttctta
    19921 tgcaaccttg ccaggaggcg gtacgacaga ctacgcagtc gatatttatt attcagcaat
    19981 caaagaagga aagtacacta gtttcattga tcaaggtaca tcaatggata tgatgtatat
    20041 gccagatgcg atcgatgcca ttataaaact catgaatgca gatcctgatc gattggttca
    20101 tcgaaatgcc ttcaatatat cggcgatgtc ttttgacccg gaagagatca aagcatctat
    20161 tcaaaaaatc ataccagatt ttgaaatgga ttatgatgtg gatcctgtac gtcagtcaat
    20221 agcagaatct tggccaaatt cactagatgt ttcttgtgcg caagaggaat ggggcttttc
    20281 gccgaaatac gacttagatg tgatgacaaa ggatatgttg gaaaaactga aagaaaaatt
    20341 ggtagagacg gtataaaaca agaaccacat ccaaaaagtt ttttatactt ttgggattgg
    20401 ctatggtatg aaaggggaca agggatggaa gaatatcaag ccacgccagt aaaagaagta
    20461 aaaatagaaa atgaattaaa acgtacgatg ggatttttta ctgctttatc gactgttatg
    20521 ggcacagtga tcggtgcagg ggtatttttt aaagccgcaa gcgtagcaga agttacagga
    20581 tccgccagtt tgcatatgtt ttcttggttt ctcggtggta tgatttctgt ctgtgcagga
    20641 ctaacaggag ctgaactggc agctgctatt ccagaaacag gagggatgat taaatatatc
    20701 gaacggattt acggaaatac agcagctttt ttattgggct gggcgcaagt cgtgatttat
    20761 tttccagcaa atgtagcagc cttgtcgatc attttcggta cacagttcgt caatctattt
    20821 ggtctttccc agtcaatgat tgttcccgta gctgttacag ctgctgtatc gatcctgttg
    20881 atcaattttt taggttctaa agctggaggg gcttttcagt cgattacgct tgtctgcaag
    20941 cttattcctt tgtttgtgat cgtcattttc ggtttgttcc gacaagaagg agtagacttc
    21001 caactgtttc cgatccaagc aggagaaaat ctttcatttt tctcagcctt gggagcgggc
    21061 ttgctagcaa cgatgttcgc atacgacggt tggatacacg taggaaatat ttcgggagaa
    21121 ttgaaaaagc cggcgaaaga tttgccaaaa gcaatttctt taggaatcat cggaatcatg
    21181 atcgtttatt tattagtaaa tgcggtgttc ttaagaaccg catctatcga cggagtcgca
    21241 ggaaacagca atgcggcaag tgacgttgca aaaatgattt ttggcggctt cggtggaaga
    21301 ctggtcacag ttggtatctt gatttctgtt tatggaacca tcaatggcta tacccttact
    21361 ggaatgcgtc tcccttatgt tatggcaaaa gaaaacaacc tgccttttag caagctcttt
    21421 gctaaacttc atgataaaac taaagttcct gtagccgcag gtatcttaga gctagtcatc
    21481 gctattggca tgatgatgat cggtggtttt gatacactaa cggatatgct gatctttgtc
    21541 atttggattt tttatacgat ggtctttgtt ggtgtcattc ttcttcgtaa aaaagaacct
    21601 gatttgtttc gaccatacaa agttccaatg tatccgttta ttccactagt agcaatcatt
    21661 ggagggactt ttatcgtatc aagcacgctt atcactcaga cctttttagc ttcgatgggg
    21721 atagtattga cacttgctgg tatcccgatt tatctctatt taaaacgtag atagctaaaa
    21781 cattcgaatt ttattagaac tgcacttctc tgccaaacaa aatattttat ttaaatgagg
    21841 agtacgtgga agaaatgtca aaagtactcg ttaattttga tcacgtaaat gtcgttttgt
    21901 ctacgatgaa atagcaaagt aaaagacaga aatcgggctc aaccgatttc tgtcttttac
    21961 tttgatttgc gtaactgaac tattcggcgt acgccgcgat aaatatttaa taaaaccaag
    22021 caaccagaaa tgaaaatggg aagccaaatc agatagacag ggtagccaag cactttagac
    22081 aaagcatgtg gagtcatttt atccatttca agaagtgctt gctgccaagt ctgaagattg
    22141 aagactagca tgaaacccga aataatcagg agaataaatc ctaaataatg aattgtagtt
    22201 ctttttctta cataagcgat cgtagcataa aggaacagta aaaaaatagg tacgccaaaa
    22261 acaaagtaca tattcagcat ctcgacaccc cctttgtgtt tatcttactt tactttgaaa
    22321 gaaatgagaa ataatagcct cgttacttgc ttgaaacagc aaaggactgc taagataaga
    22381 gagatacaaa gaatcaagga ggagtcatat ggcaagttat atcgaaccga ttcgttttgc
    22441 gctgattgtt tttccatttt tagccttagc gatctcatct gtttttttta tttatgaata
    22501 tcgaaagtat ggaacatttc tagtaacaag ggcagttatt ttgtattctt tcgtttttta
    22561 tttattgtgt gcgtattttt tggtgatctt accacttccg gcaaaggaga cggttgccca
    22621 aatgacaggg ccaaagatgg agctgcattt atttgcttca tggcaacatt tcagagacaa
    22681 cacggtattg gtcttgtctg aacctagtac ctacctgccg gcaatgaagc agagtgtatt
    22741 tttggaacca gcttttaatg ttttattact cataccattt ggcatttatt taagatatta
    22801 tttccggctt tcttttatga aaacgatgat tgctagtttc tgcctttctc tattttttga
    22861 attgacgcag ctaagtggac tttattttat ctacccaaga ccataccgct tatttgatgt
    22921 gaatgattta gtgacaaata cattgggtgg aatcattggt tttgtcgtta cgccgttatt
    22981 tacatttatg cttcctacaa gaagacgaat ggatgaactt tcttatgaaa aaggaaagac
    23041 tgtctcattg actcgacgct tggtcgctta tttgatcgac tggacatttt tatctcttat
    23101 taatttggta gcggcgattt tctttaaaat tgcgttcgat tcaggggcag ttacttctca
    23161 tatctggtgg cttttattag aagtaggggt atactttatg attgtaccgt ttataaccaa
    23221 tggatggaca cttggcaaaa aaattgtgcg tatccgtttg gtggaagaag accgcgaacg
    23281 aatttcttta aaagcattga tgatccgcta cgggtatctg tactttcttt tttatggttt
    23341 aagctggttg gggcagttgc ttcagcaaat catgaattcg acaacgaata cggtgttgca
    23401 gatgagtgca gtattcattt ctctcggtgt cttgttacta caaggtattt ttattttaaa
    23461 tatcttgcta tcatttttga gaaaaaaacg gattctgttt tatgaaaaag ctagtcacac
    23521 atatactgtt agcacgattg gccaaacaaa ggatgatgat tctcgaaatt agctgagcaa
    23581 aaacgctttg tctgtgttat aatgccaaag tcgtgataat ttaaagagaa gaggtgcacg
    23641 aatgaataat tttgatatat tccgcttcaa accgtttatc aatgaagcgt taaccgcaaa
    23701 gggcttcaaa cagcccacag aggtccagga acgtttgatt cctttaattg caaaaggaaa
    23761 aaatatcatt gggcaatctc aaactggtac aggaaaaaca catacgtttt tgttgccttt
    23821 gtttgaaaaa atcaatgcag aaaaagagga agtacaagtt gttattacag ctccaagtag
    23881 ggaactagct gcacagatct atgaagcagc tacacaaatc gctaaatttt ctacaccgga
    23941 gatccgtgtc tcgaattttg tcggcggtac agacaaacag cgtcaattaa atcgtctgca
    24001 tcaccaacag ccacaggttg tagtaggcac gcctggtaga atattagaca tgatgaatga
    24061 acaagcgctg aagattcaca ccgcatttgc atttgttgtc gatgaagcgg atatgacatt
    24121 ggatatgggt tttttaaatg aagtagacca aattgcaagt cgattaccag aaaagctgca
    24181 gtttttagtt ttttctgcca ctattccaga aaaacttcgt ccattcttac gaaaatacat
    24241 ggaaaatcca atcattgaag aaatcaaacc aaaagcagtt atttctgaag acattgaaaa
    24301 ttggctgatt tcaacaaaag gtaaagatga gaatcaaatg atttatcaac tgctgacaat
    24361 tggtcatcct tatttagcaa tcgtatttgc caatacaaaa cagcatgtgg atgaaattgc
    24421 cgattacttg aaaaaccaag gcttgaaagt agcaaagatt catggagaca tcaccccaag
    24481 agagagaaaa cgagtgatgc gacaagtaca gaatctggag tatcaatatg ttgtagcgac
    24541 tgatttagct gctagaggga tcgatatcga aggtgtctct catgttatta atgcagaaat
    24601 tccagaagat ctagacttct ttatccatcg tgtcggacgt actggacgta atggcttaaa
    24661 aggaacggcc attacgttat attcgccaaa tgatgagcaa gccattgatg cgatagaaaa
    24721 attgggcgtc tcatttgaac caaaagaaat caaaaacggg gaaatcgtca aaacatacga
    24781 tcgtaataga cgtgccaaac gagaaaaatc aaaagatgta ttagatccca cgctgattgg
    24841 tcttgtgaag aagaaaaaga aaaagatcaa gcctggttat aagaaaaaaa tcgattgggc
    24901 aattgcagaa aaaaataaaa aagaacgcaa aatcgaacgc agacagcaaa gccgtactgc
    24961 tcgtaaaaat aagaaaaatt cacataaata aaaaacaaga ggttgtgaca aaaggcgtgt
    25021 cacaatctct tgtttttaag ctagactttt tttcattccg atacaaagta cttcatcttc
    25081 aataaaaggt tctgtgcaag tatgataccc ttgtttttca taaaaatcta cagccgtcat
    25141 ttcagctact acataactag tctgacaacc ttctgaaacc gcccgttttt cagcagcttc
    25201 aagcaactga ccgcctaacc cttttcctcg gtattctttt gctacgcaaa atcgttccgg
    25261 cttgaagcaa gtaggtgttt tcttttcata acgcaaagta gctactggtc ttttttgatc
    25321 aagaaataga taataggttt gttgcgggat atcttttccg tcgaattcta gttctgcagg
    25381 aatcccttgt tctaatacaa aaacttgata tctcaaaaag cagctagctg cgcgtatcca
    25441 ttcatccgct ccaactattt ttttcatcat attcctcctt gtcatgaata gcagagatgt
    25501 attgattcct ttattcttat cgtaccaaaa atcgtggagt atgaccaaaa ggaaatgaaa
    25561 ataaaaattg agatattgac agtgatcaat agaatgcgta tactaaataa gtacgaaaag
    25621 gatatgattt gttttttaag actcacagaa aattctttct tggctgaaaa aagaatagtc
    25681 actaatcaaa ttgctccctt tttctatttt ggtagaaata ccgacgcagc tcagcgttat
    25741 cgagtttaag aggtaatgat tacacatcat tgcaatcaag gtggtaccgc gagttttcgt
    25801 ccttggctgt gatggtgttt ttttgtattt aatttataga aagcaggtaa tgacatgaaa
    25861 caattaagta gtgcacaagt tcgacaaatg tttcttgatt tcttccaatc taaaggacat
    25921 acgattgaac ctagtgcgtc tttgatcccc gtgaacgatc caaccttatt gtggatcaac
    25981 tctggtgttg caacattgaa aaaatatttt gatggttcag ttgtgccaga aaatccaaga
    26041 atcacaaatg cccaaaaatc tattcgaaca aatgatatcg aaaatgtcgg taaaacagca
    26101 cggcaccata cgatgtttga gatgctgggt aatttttcga ttggtgacta tttcaaaaat
    26161 gaagccatcc actgggcatg ggaatttttg actgatccaa aatggatggc attcgatcca
    26221 gaaaaacttt atgtaacagt ttatccaaaa gatacagaag caaaacgcat ctggcatgaa
    26281 gaagttggcc tgccactaga tcacattatt gatgtagaag acaacttctg ggatatcggt
    26341 gcaggcccat gtggtccgga tacggaaatt ttctatgacc gtggagaagc ttataacgat
    26401 ttagcagaag acgatcctga aaactatcca ggaggagaaa atgaacgtta tttagaaatc
    26461 tggaacttag tattttcaga attcaaccat aagcctgata acacatttga accacttcct
    26521 cataaaaaca ttgatacggg gatgggattg gaacgcatgg tctcaatcgt tcaagatgcg
    26581 tcaacgaact ttgagacaga cttgtttatg cctattatcc acgccgtaga aaagctaagc
    26641 aaacaagtaa aatatggtga aaacccagta acagatattt cttacaaagt aatcgcagat
    26701 catattcgcg ccctttcatt tgctattggc gacggtgcat tgccatcgaa tgaagggaga
    26761 gggtatgtct tacgccgttt gcttcgtcgt gctgtcatgc atgggaaaaa attaggtatt
    26821 gaacaagcat tcttatatcg tttagtccct gttgttgggg aaatcatggt aagttattat
    26881 cctgaagtac ttcaacaaaa agaatttatt gaaaaagtta tccgtacaga agaagaacgt
    26941 ttcaatgaaa caatcaatga aggtttggaa atcttaaatc aagtgatcca agaagtaaaa
    27001 aacgaaaacg ggacgactct agcaggaaaa gacatcttca aactatacga cacatatggc
    27061 ttcccggtag aattaacgga agaggtggca gaagatgaag gactgaaagt tgatcatgct
    27121 ggttttgaaa aagaaatgga tgcacaacgc gaacgtgctc gctctgcccg cagtactgaa
    27181 aaatcaatgg gggtacaatc tgctttattg acagatatca aagtagaaag taaattcatt
    27241 ggatacacag aacaagaatc agatagtcaa ttattggtca tcgttaaagg tgagtctctt
    27301 ttgaatgaag tcgcagaagg tgaagctcaa atgatctttg atcaaacacc tttctatgca
    27361 gaaatgggtg ggcaagtagc ggatcaagga tggatcatga atgaagtagg cgaaatcgta
    27421 gcagttgtta cagatgttca aaaagcgcct aatggtcaat ttatgcacac cgtagaagta
    27481 aaagcaccaa tgagtgaagg acaaacctat catctattga tcgatcaatc gatgcgcaat
    27541 cggatcatca aaaaccatac agcaacccat ctactgcaca aggcattgaa agaagtactt
    27601 ggcgagcatg caaatcaagc tggttcttta gtcgctcctg gacatttacg attcgacttt
    27661 acccactttg gtcaaatcac ttcagatgaa ttagctgaaa tggaaagaat cgtcaacgaa
    27721 aaaatctggg aagctatccc agttgaaaca attgaaacag atatcgatac agccaaaaac
    27781 atgggtgcaa tggctttgtt tggtgaaaaa tacggacatg acgttcgagt agtaaatatt
    27841 ggcggctggt caatcgaact gtgcggaggc acacatgtag caaatacaga aaacatcgga
    27901 atcttcaaaa tcgtttctga atcaggaatt ggtgcaggcg tgcgacgaat cgaggctgta
    27961 acaagtaaag aagcgtacga actacttgaa gaagaagaaa aacaactaaa acaagtagca
    28021 acaattgtta aatcacctca attgaaagaa gttgtttcaa aagcggaaca attgcaacag
    28081 caagtaagag agctacaaaa ggaaaatgaa caattagcta gcaagttagc gaatcaacaa
    28141 gctggtgatg tattcaaaga tccagaaacg atcaatggaa aaacaatcat tgcagcacaa
    28201 gtaaaagtga aagatatgaa tcagctgcgt caattagctg accaatggaa acaaaaaaat
    28261 atttcagata ttcttgtttt agcaaacgaa caagaaggaa aagtcagtct gctagcggca
    28321 atgacgaaag aatcaaatga agctggacta aaagctggcg acttgattaa agcaatcgca
    28381 ccgaaagtag gcggtggcgg tggtggacgt ccagacatgg cacaagctgg cgggaaaaat
    28441 cctgctggta ttccagatgc acttaaagct gcgaaagaat gggttgcgca acaatagggc
    28501 gtttacgttt gacagaaaaa caaaagttca aacattgaac gaaacatgat tatgggggcg
    28561 aagacaaaca agtcttgccc tcatactttt ttcaattgga tggcgcatct aatcaaatgg
    28621 tcggattcgg atggtcttta gttgacgaaa gtgacagaaa tttttacgat tagtataaat
    28681 aaaaaggggt gaaaaaatga atagtagaaa taagaccttt cgactagtct tacgtgcgat
    28741 cttgttagca atcatcatcg tacaagcgat ggttccttgg ctggggttta ttccattagg
    28801 attcattagt ttaacaatta tccatatcac agtaattatt gctgcagtag tattaggccc
    28861 aaaagatggc atggtgattg gcttgttttg gggaatcgct acaattgttc gtgcctatgc
    28921 catgccaaca acgccatttg atacattagt gttcacgaat ccgattatct cggtagttcc
    28981 cagagtactt gttggcttag tagcaggctt ggttttccac tggatttatc aaaaaaataa
    29041 atcaataacg atcagctcag cctttgcagg ggtactgggt tcattggtca atacagtctt
    29101 agtgttagga ttcatgggat tattttatac aggtgcaacg gcagatgcct atggtgtaga
    29161 ctctgctctt ttatttaaaa ccttagcagg ggttgcagca atcaatggga taccagaagc
    29221 aataggtgcg ggaatcataa caccattact agcaaaagcg ttatttgcag caacaccgtt
    29281 gaaaccagaa taatgaccat cttttaatag taataggacg cacgatagat agaaaaagga
    29341 agagaggaga ggaaaacaat cgtcctctcc atctttttac ctgagcaaca agcaaactag
    29401 aaggggtaaa aaacttggct aagaaacaag aagaaaaaaa gaaacaaata ccgcaacagc
    29461 ggacaaaaaa aggagtacta gcgggtatct taggattggt tacgaatctg atcttgtttg
    29521 tctctaagct aatgatcggg cttttttcag gaagtgtctc cattatggct gatgcagtga
    29581 acagtctatc agatactgct tcatccatat tgactttgat cggatttaaa attgctgcaa
    29641 agccagcaga tcaggaacat ccttatggac acgaacgctt cgaatatatc agtgggttat
    29701 ttgtttcgat catcattact tatgtaggat ttcaattttt agagtcttct gctgaaaaaa
    29761 tcatccatcc agaaaatgtc tctttaacac ccatcgtctt ttttgtccta atcatttcca
    29821 tctttttgaa atttgcacaa ggcaaaatgt atcaggttat tgcgcaatcc attgattctg
    29881 aaacattgag agctacagca acagatagtt ataatgatgt ctttactaca ctggctgtat
    29941 tgctttcagc agcaatcgaa tgggtaactg gatggcgtat tgatggatat ataggttttg
    30001 ctttagcatt atatatcctt tatagtggat tgacgatgct tcgaaatttt gtatacgaac
    30061 tattaggaag tcgcccaacg ccagcagaga ttgaagaaat ggaagagcat ttaaatgctt
    30121 gcgatgatat acttggctat catgatttat tggtgcataa ctatggaccc aataaacgct
    30181 ttgcatcagt ccacatcgaa gtagatgaat caatgaattt gaatgtggct cataagatta
    30241 ttgatctgat agaaaaagac tttaaaaagt ctttggatgt ggaacttgtc tgtcacttgg
    30301 atccaatgcc tgttgataac gaaaaatact ataatatctt gcggcagtta aagcaaattc
    30361 ttcttgaaac aggtacaggg cttaatattc atgattttag agtaattcat caaggaaaaa
    30421 cgctgcaatt tgatgtagtg gtccctgaga aattccagtt tgttgataca gaactagaaa
    30481 gaatcttacg tagtcaaata gaagaaaaaa tcggagatta ccaattggaa attacgtttg
    30541 atcacaatta tcttttatat taaatgagaa actataaaaa gactccttaa agtttttaat
    30601 ttaaagagtc tttttttctt ttaattgttt atggagagcc tgacgtgcaa gattatctgc
    30661 tcctttattt ttgttttcgg gcaaccattg caggatcaat aaagaaaatt cggatagaag
    30721 ttcttggatt ctttgaaggt agggaaggaa gagctcgttc ttcgttgcgt ttttgtcgac
    30781 cgtagaaact agtgttttgc tgtctgaaaa acagaaaatc gtttcattct gtaagtcgtt
    30841 tttctttaga aattctaaag tttttaaaaa gacttcgaac tctgcttgat ggtttgtccc
    30901 tatagaaagc gggatagata gctgttcttg tttaccttga tagacaatca agattccacc
    30961 tccactagga ccagggttgc cttttgtaga ggcatcaatg tatactttta acataaaaag
    31021 agattctcct ttttgttcaa actaatgtta tggtaagatt atatcattac tgaatcggtg
    31081 agaggttaga gaatgaaaaa aaatattcga tggcagcctg aactggcaca tacgatcatc
    31141 tattggtcat tgaccttgat cattctgttt tttagtctga ttctttcttt agaaaacaca
    31201 ggtccttatt ggaaaagcaa ttttgtttta ggtatttttc ttgtttttct atttctaggt
    31261 ttgcggcgtt cttttatttt aaaatcaaac tctgtgatta tacgttatgc tgctttttgg
    31321 aaagaccgag aaatatctgt cggacagatt cgatctttga cgccaactaa tactggggtg
    31381 caaatgatgt tgcaagatga gaaagcccca tctgttttca tgatgcgaaa aaaagatcaa
    31441 gtagtccttt ttgatcattt tgaaaaaaac ggacccaaat cagaatcaat tccttatcct
    31501 tatacgaaaa aaagaaaaag ctaattttaa aaatcagaac ctaaaaaaac gaatttttac
    31561 aggaaaagaa aagagtgaga cgtacggttc atcccgttta gcgtctcact ctatttgttt
    31621 atctattgat gcatactagt atcggtagtc tgaacgttgc ctttcttgac atgggcagct
    31681 tgtgttcctc gattcccttc gatgatctca aattcgacca cttgattttc ttccaaagtt
    31741 ttgaatccct cttcttcaat cgcagtaaaa tgtacaaaaa tttcttctgt gtcatcataa
    31801 ctgataaagc cgtatccttt tttgttgtca aaccatttta caattcctgt ggtcaaagca
    31861 ctcacgacct ttctaaagtc tgatcatagc cttcattata aagagtattt ataagtacgt
    31921 caaataaatt aaaaacctgt aattttatgt tttttttctg aataaaaaaa ggtataattg
    31981 gcatatctta acaaagaaga tattttgttg aataaagttc gtgaaaaggg gtaatcaaat
    32041 gaagaatgat ctgcaaattt cacaagaaac agagctagaa ccgattgttg aagtggctag
    32101 taaattagat cttaaggaag acgatttgga actgtatggg aaatataagg cgaaaatcaa
    32161 tttttctgga atcaatcgat caaaggataa cgctgagggg catttgatct tagttacttc
    32221 catcaatcca acaccagctg gcgaaggaaa gtcaacgatc actgtagggt taggagacgc
    32281 gctcaataaa atcaataaaa aatctgttat tgcattgcga gaaccctcac ttggtcctgt
    32341 gatgggaatc aaaggtggtg ctgcaggcgg aggatatgca caggtattgc ctatggaaga
    32401 tatcaacttg cattttactg gtgacatgca tgctatcaca acagctaata atgcattatc
    32461 tgctctttta gataatcata ttcatcaagg aaatgaattg aacatcgatg cccgccgagt
    32521 gatttggaaa cgggtagtcg atctcaatga tcgtgaactg cgtaaagtaa ttgttggctt
    32581 gggtgggcca atccaaggtg ttccaagaga agatgggttt gatatcacag ttgccagcga
    32641 aatcatggct atcttgtgtc ttgcggcaga ccttgaagat ttaaaggctc gtcttgcaag
    32701 gatcgttgtc ggctatacat ttgaccgtca gcctgtgact gctggagact tgaaagcaga
    32761 aggcgctctg gcattactgc tgaaagatgc aatcaagccg aatcttgtac aaacaattta
    32821 cggaacacca gcttttgtcc acgggggacc gtttgccaat atcgctcatg gctgcaatag
    32881 tattttagct accaagacag cattgagatt agcagattac gttgtcacag aggcaggatt
    32941 tggtgcagat cttggcggag agaaattttt agatatcaaa gtacctaact tgaaaaaagc
    33001 gccggatgct gtggtgattg tcgccactgt ccgtgcattg aaaatgcatg gcggaatgaa
    33061 aaaagatgaa cttaaaaatg agaatcttga tgctttgaaa gtaggttttg caaatttaaa
    33121 gcgccatata cgtaatatgg aacaatatca gctacctgtg atcgtcgcaa tcaatgaatt
    33181 cgtaacagat acagacaatg aactcacact gttggagcac ttgtgtgaaa atcaggggat
    33241 tcttgccaag agagcgagtg tatgggcaga tggagcagaa ggcggcgttg atttagcaaa
    33301 agctgtagta cgattgattg atagaaaaga agctaattac aagccattat accgcctaga
    33361 agaaacgata caagaaaaga cagaaacaat cgtcaagaaa atttacggag gaaatggtgt
    33421 tgttttcagc aaaaaagcgc aaaaacaaat agaagagttt acgaagaatg gatgggacaa
    33481 actgccgatt tgtatggcaa aaacacagta ttcattttct gatgatcctt cactgctagg
    33541 tgcaccggaa gatttcacca tcacgatccg cgaaatcatc ccaaaattag gggcaggatt
    33601 tttagtagcc ttgactggag atgttatgac gatgcctggt ttgcctaaaa aacctgctgc
    33661 attgaatatg gacgtgacaa atgacggaga agtgttggga ttgttttaag cttgattata
    33721 atctaccatc gaaggagctg tattttgact acagcttctt tttttagacg atagggaatt
    33781 aattttgttt acactaggat cattcttttt ctttattgta ttttgagcta tactaaagca
    33841 taataggagg gtatgatgaa aacgacattt ataagaaaaa ccggttttta cggtatgggt
    33901 agctcgattc agctaagaat caacaatgaa aaacgcagtg ttctcagtca tgaacaaaag
    33961 ataacgcttg atctggaagt gccctttacg atgcaggtca ccttttattg gctaaaaagc
    34021 cccgtttata cagtgaaaga agcaaagcct gcttatgtga tcacaatgaa ttacttgatt
    34081 cttcaaatct atccgttttt atttctagca actgggttgg gggccgtttt cctacaaaat
    34141 ttatttttca gtttttttgc agttattgtg ttgattgcgt tctttttcta tataaaaaac
    34201 cgggcatatt tgatcaagga ggaaaattat ggcaaactct gatctttttt taatcagttt
    34261 caatcgaatc gaaaaatgga tgagagacga gatgggaaat gcacgaaata tgggatttac
    34321 cgaacttgtc agacgcctag ctcaaagaaa acaattaatg atcagaaaat acgaagatga
    34381 tcttttacag cttgctcagt taaggaatgc gatcgtccat gatcggatcg cagtcgattt
    34441 tgtcattgca gagccaaatg attggacagt caagcgaatc cagctgatcg aacaagaact
    34501 gattcagcct gaaaccgtgc tgcctcgatt tgcaaaacgt gtaacaggtt ttgaacaaga
    34561 tcttccgtta cttgaactgt taaagatagt agcagaaaaa aggtattcac aatttccgtt
    34621 atacaataaa ggaaaatttg tagcattgat tactttacgt aatatcgggt tttggctagc
    34681 aaaagaaagc caaaaaggtc cggttgattt aacaaataaa cgagcgttgg atttgatcat
    34741 ccaaaacgga aagtacacaa attatcattt tgttccagct aaaacacata tttacgaggt
    34801 tgaagcgatg tttcgtgagc aagggacttt ggaagccgta cttatcacta aagatgggaa
    34861 tcccgatggt aatctgctcg ggatcgtacg acctcgtgat atttataaac aaatagaaaa
    34921 ggattgattt tttgttaatt atttattgga tattcagcgc tttgctagta ggagtggatc
    34981 agttggtcaa atggtggatc actgataatc tagcgcttgg agagacgaaa aatcttatac
    35041 caggtatttt gtcactgaat catattcgaa acactggagc cgcatggagt atgctagaag
    35101 ggaagatgtg gttctttact atagtgacac tcattgcagt cgttgtgatt ctcacattga
    35161 tgattaaaaa tcgtgaaaaa ggtaatcgct ggttcatgat tggattgagt ttgattctag
    35221 ctggtgcgat tggcaatttt atcgaccgta ttcgtcttgg ctatgtagta gatatgttcc
    35281 agacagattt tatgagcttt ccgattttta acgtagcaga tgtgacactt gtatgtggag
    35341 tgatttgtat gttaatttat attattttag atgaaaagga tcaaagaaaa aaatgacaga
    35401 acttaaaacg acgattcacc atgaatctgg taggatcgat aaagtattga ctaatttatt
    35461 caccgattac agtcgttcgc aaattcagct gtggctgaaa aatggagcgg tttctgtcaa
    35521 tggacagcca gtcaaagcaa attacaaagt aaaacaagga gacgagatta ctgtcttgat
    35581 ccccgaacca gaaacattag atgtggtccc agaaaatatc ccgttgacga tcgtttacga
    35641 agatgaagat gtagcggtga taaacaaacc tcaaggaatg gtcgttcatc cttcagcagg
    35701 tcatacgcat ggcacaatgg tcaatgcgct gatgtaccat atcaaggatc tttctacgat
    35761 caacggcgtt attcgtccag gtattgttca ccgaatcgac aaagatactt ccggactgct
    35821 aatggttgcc aaaaatgacc aggcacacga atcattagct cagcaattaa aagataagac
    35881 ctctttgcgc aaatatgttg ctttagtcca tggagagatt cctcacgaaa aaggaaccat
    35941 caatgcgcca atcggccgtt cgaaggaaaa ccggaaaatg caggcgataa gagaagatgg
    36001 gaagtcggct gtcacacatt ttactgtatt ggaacgtttc gaaggattta ctctggttga
    36061 attaaaacta gaaaccggaa gaacacacca gatccgtgtg catatgaagt atatcggtta
    36121 tccgttagct ggagatccag tatacggacc gaagaaaact ttgaaaggca atggtcagtt
    36181 tctccatgcg caaatgttag gttttacgca cccgactaca aacgaaaaga tgatctttga
    36241 agcacctctt ccagaagttt ttgaaaaaac tttagaaaaa ttaagaaaaa acattgcatt
    36301 ttaatttaga taacggtata gtaattaaca acgaaagcat aaaacttaat agaattcctt
    36361 taagtttagt cccgtgaggc taagaagggt gggagcaagg atacgtatgg tgcgccataa
    36421 gtagattgct cattgacata gtatagctat cagtgtatca gtatacgctc agtctaaaca
    36481 ttcctcctgt cctcttaggg caggagtttt tttatgcaaa aaagtagggg gaatgaaaat
    36541 gcaagcaaaa gaagtagtag atcaggtaac catgaagcga gcattgactc gaattactta
    36601 tgagattatc gagagaaacc atagtatcca agatatcgta ttggtaggta tcaaaacacg
    36661 aggaatctac attgcatcaa gaattgccga acgcctgaag cagctagaag atatcgatat
    36721 tcctgtagga gaactggata tcactttata ccgagatgac aaaaaagaaa atccagaaga
    36781 accggaactt cattcttctg acatcccagt ttccttagaa ggaaaagaag ttattttgat
    36841 tgatgatgtt ttgtatacag gacgaacgat tcgagcagca atggacgcag taatggattt
    36901 tggcagacca agaaaaattt cattagcagt cctggtcgat cgtgggcatc gagaattgcc
    36961 aatccgtgca gattatgttg ggaagaacat tccaacatct cgggcggaag agattttagt
    37021 agagatgcaa gagcttgatg gacaagatcg catcatgatt ttgaaagagg aagattagag
    37081 gagagagaaa catgtcggag aaaaaaggat ttcataatga tgacgtggtg ttagatatcc
    37141 acgatcgccc aaccccagga cattgggtag gattaagttt acaacacttg ttcacgatgt
    37201 tcggagcaac cgtgttagtc cccatcttag taggtatcga tccaggtatt gcgctagtca
    37261 gttcaggact aggtacattg gtgtacttat ttactactaa aggaaagata cctgcgtact
    37321 taggaagcag cttcgctttc attgcagcga tgcagctttt gatgaaaaca gatggttatc
    37381 cagcgattgc acaaggagca gtcacaactg gattagtcta tttgattgtt gcgctgatca
    37441 tcaaaaagat cggttcagca tggctggata aaatcttgcc tccaatcgtc gtcggtccag
    37501 tcatcatggt tatcgggttg ggacttgcgg caaatgcagc aacaaatgct atgtataatc
    37561 agggcacgta tgatttcaag tatattgctg tagcgctgat cacattagga ttaacaattt
    37621 tcttcaacat gtggctaaga ggttttctcg gattgattcc gattttacta ggtattatta
    37681 gcggatacat cgtagccttg ctgtttggaa tcgtggatac taagccaatc gtagacgctg
    37741 cctggtttgc tgttcctaac tttgagattc cctttgtaca atatgaacca aagctatatc
    37801 ttggagcaat cacaacaatg gcacccatcg cttttgtgac gatgacagag catatcggcc
    37861 atcttatggt attgaataaa ctaactaaac gtaatttctt tgaagaaccg ggtcttcata
    37921 agacgttgac aggtgatgga ttagcacaaa tcgtggcagc ctttgtcgga ggtcctcctg
    37981 taacaagtta cggtgaaaac attggtgttc tggctatcac acgtgtccat agcgtgtttg
    38041 tgatcggtgg agctgcagta tttgcagtca ttttaggatt cgtaggaaaa ttaagcgctt
    38101 tgattttaag tatccctgga ccagtcatct caggaatcag ttttatctta tttggagtaa
    38161 ttgccgcaag tggaatgaag attttaatcg agaacaaaat cgattttgat aaaaagaaaa
    38221 atctgttgat tgcttcagtt atcttagtag taggaattgg cggactcgtc tttgaagtag
    38281 gcacatttac attgtcggca atggcattag caactgtact tggcatcatt ttaaatctta
    38341 tcttaccaga aacttcacga agcgaagaaa actaaggagg aaacattatg atcatcaaat
    38401 cagaacgtat cagcttaaag catttattga ccgttgaggc acttactgat caagaagtta
    38461 tgggcttgat ccgcagaggg caggaattca agcaaggtgc taattggact ccgcaaaagc
    38521 gccagtactt tgctacaaac ctctttttcg aaaatagtac tcgcacacat aaaagcttcg
    38581 atgtagcgga gaaaaaacta gggctagaag tgattgaatt tgaagcaagc acaagctctg
    38641 tccaaaaagg ggaaacacta tacgatacag tactgacgat gtcagcatta ggcgtagacg
    38701 tagcggttat ccgtcatggt gatgagaact attatgacga actgatacaa agtaaaacaa
    38761 tccagtgttc gattatcaat ggaggagacg gaagcggaca gcatccaacc caatgcttgc
    38821 ttgatttgat gaccatttat gaagaatttg gtcattttga aggtctgaaa gttgccatcg
    38881 taggtgatat cactcactct cgcgtagcta aatccaatat gcagatgtta aaacgtctag
    38941 gcgcacaagt attcttctca ggtcctagag aatggtacga cgatgaattc gaagtgtacg
    39001 gacattatat gccattggat gaactactag atcaagttga tgtcatgatg atgcttcggg
    39061 tgcaacacga acgccatgat ggaaaagaaa gtttctcaaa agaaggctac catcaggaac
    39121 atgggttaac agttgagcgt gcgaagaagt tgcaaaaaca tgcaatcatt atgcacccag
    39181 caccagttaa ccgtgatgta gaattagctg attcattagt ggaaggatta cagtcgcgga
    39241 tcgttcagca aatgagcaat ggagtattcg tcagaatggc aatcttagaa gcagtgctaa
    39301 atggaaaagc gtaattatag gaggatgaaa aaatgaaaac actcattaaa aacggtcaga
    39361 tcaatacacg aaaaaatatg acgacaccag cagaaatttg gatagaagat gggcgaatca
    39421 aagcaatcgg tacaggattc tcagaagccg aatttgatga agtgtttgat gcaaagggac
    39481 aattgatcac acctggttta gtggacgtcc atgttcattt gagagagcca ggatttacat
    39541 acaaggagac gatcgaagct gggactcgct cagctgctcg tggcggtttc actactgtat
    39601 gcgcgatgcc gaatttaaat cctgtacctg atacggcaga aaagctgaga caagtatatg
    39661 acatcattag aaaagatgca gttgtgaagg tattgcagta tgcgccaatc acagaaaatc
    39721 tgcgaagtga gaaattagtt gatcaagaag cactgattga agaaggtgct tttgctttca
    39781 caaatgacgg tgtaggtgtc caaacagctg ggacgatgta tctggctatg aaagaagctg
    39841 caaaaaacaa taaagcccta gtagcccata cagaagatga atctttatta tttggcggcg
    39901 ttatgcacgc tggcaagaag gcagaagaac ttggtcttcc cgggatctta agcgtaaccg
    39961 agtcttctca aattgctaga gatctgttgc tagctgaagc aactggtgtt cattaccatg
    40021 tttgccatgt ttctactaaa gaaagtgtcc gtgtaatcag agacgcaaaa aaagcaggaa
    40081 tccacgtaac agcagaagtt tcaccccatc atcttatttt gatcgacgaa gatattcccg
    40141 aagatttcgg cttttggaaa atgaacccgc cgctaagagg acgggaggac agagaagctt
    40201 tgatcgaagg cttgcttgac ggtacgatcg attgcatcgc tacagaccat gccccccatg
    40261 gattagaaga aaaaagccaa agtttcatga aatcaccatt tggtatcgta ggaagcgaaa
    40321 cagcgtttca actgatctat actcattttg tagaaactgg tcgattcacg ttggaacaag
    40381 tgatcaattg gttggcagtt aaaccggctg agatttttgg tttgaatgca ggaacgctaa
    40441 cggttggtgc ccccgctgat gtagcagttt ttgatattac acaaacttgc acgatcgata
    40501 aagaagactt tttatcaaaa ggggagaata caccttttat cggctggaaa gtaaaaggcg
    40561 aaacacaaat gacttttgtc aacggaaaac ttgtgtggca gaagggagaa taaaagtatg
    40621 gaacgtttgc ttatattaga agatggaaca gttttcgaag gaaaggcttt tggtgcagat
    40681 gctagtgtct tcggagaaat cgtttttaca acaagtatga ctggttatca agaaactatc
    40741 actgatcaaa gttttaacgg tcaaatcatt acatttacct atcctatggt gggtaattat
    40801 ggggtaaata gagatgatta tgaatcgatt tctccaacat gcaaaggagt agtagtaaaa
    40861 gaacatgcac gtgtagcttc aaactggcga aaccaaatga cgctagattc atttttgaaa
    40921 caaaaaggaa ttcctggaat atcaggtatc gatacgcgcg cccttactcg caaaatccgt
    40981 gaagtcggaa cgatgaaagc tagtatagtt gatgctggag attccttcga acatgcattt
    41041 gatcagctga aagcaaccgt tctagcaacc aatcaagtgc agcaagtctc aactaacaaa
    41101 ccttatccaa gtccaggaac aggtcggaaa gtcattgtca ttgacttcgg cttgaaacat
    41161 agtattttac gagaattgag taaaagaaac tgtaacctca cagtacttcc ctataacaca
    41221 gatgccgaga cgattttagc gctatcacca gacggagtca tgctgacgaa tggacctggt
    41281 gatccaaaag atgtgccaga agcaatcgaa atgatcaaaa aaatccaagg aaaagtaccg
    41341 atttttggta tttgtctcgg tcaccagtta tttgctttag ccaacggtgc agatacctat
    41401 aaaatgaaat tcggacatcg aggattaaat cacccggtac gagaagtagc gaccggaaga
    41461 attgatttta cttctcaaaa tcatggctat gcagtcgatg aagccacgat tgatccagaa
    41521 aaactcatcg taactcatgt agaagtaaat gacggaacag tagaaggagt caaacacaga
    41581 gattatcccg ctttcagtgt gcagtttcat ccagatgctg cccctggtcc gcatgatgca
    41641 ctacatttat ttgatgaatt tatggaaatg atggacgcag gaaaggagca gtaaacagat
    41701 gccgaaacgt acagatatca agaaaattat ggtgattgga tctggtccga tcatcattgg
    41761 tcaagccgca gaatttgact acgcaggaac acaagcctgc cttgccttaa aagaagaagg
    41821 atatgaagtg gttttagtaa attctaatcc tgcgacgatc atgacggata aagaagtggc
    41881 agatcaagta tatatcgaac cgatcacact tgaatttgta tcaaggattc ttcgaaaaga
    41941 gcgtccagat gctctccttc caactttagg cggacagaca ggcctcaata tggcaatgga
    42001 gctggcagca tcaggtattt tagaagaatt gaacatagaa cttctaggaa caaagctttc
    42061 tgcgatcgat caagcagaag atcgtgatct attcaaacag ttgatgaaag aattgaatca
    42121 gccaatcccc gagtctgaaa tcgtcaatac agtagaagaa gctgtagatt ttgcaaataa
    42181 aatcggctat cctgtcatcg ttcgtccagc ctttacttta ggcggaactg gtggaggtat
    42241 gtgtgaaaat gaagaagaat tacgtatcgt atcagaaaat ggattaagtc tttcccccgc
    42301 tacccaatgt ttgattgaac gaagtattgc aggttttaaa gaaattgaat atgaagtgat
    42361 gagagattcg gctgataatg caatcgttgt ctgcaatatg gaaaattttg acccggtggg
    42421 tatccataca ggtgattcta tcgtatttgc ccctagtcaa acattgtctg accatgaata
    42481 tcaaatgctt cgtgatgctt ctctttcgat tattcgagca cttaagatcg agggaggctg
    42541 taatgtccaa ctcgctcttg atccacatag ttttaattat tatgtgattg aagtcaatcc
    42601 gcgtgtttct cgttcatctg cgttagcaag taaggcgact ggctatccga tcgctaagct
    42661 agctgctaaa atagcgcttg gattaacatt agacgaaatg aaaaatcctg ttacaggaac
    42721 gacttttgca gaatttgaac ctgcattaga ttatgttgta gctaaaattc ctcgctggcc
    42781 gtttgataag tttgaaaacg gagaacggct tttaggcacg cagatgaaag caactggtga
    42841 agtgatggct atcggtcgga atatcgaaga gtctttattg aaagctgtgc gttctttaga
    42901 aatcggtaca caccatatcg aacttcctga gttggcagac atcacggacg atgacctaat
    42961 ccaaaaagtg gttcgagcac aagatgatcg cctgttttat gtagctgaag ctattagaag
    43021 agggtacacc atagaagaat tagcggattt gacaaaaatc gatttattct ttttagataa
    43081 actgttgcat atcgtagaaa tcgaacagca gttgaaacag cagccgttgg atgacaagat
    43141 attgaaaaca gcgaaacaaa acggttttac agacaaaaaa gtggcggagc tgtgggaaat
    43201 aaacgaagaa gccgttcgcc agatgagaaa agaaaatgat ttgattcctg tatataagat
    43261 ggttgacact tgtgcagcgg aattcgaatc aaaaacacct tatttttata gttcctatga
    43321 atatgaaaat gaaagttcac gatcagaaaa gccctcaatt ctagtactgg gatctggtcc
    43381 tatccgtatc ggacaagggg ttgaatttga ctatgcgact gtgcattctg tcaaagcaat
    43441 ccagcaggca ggatacgaag caatcatcat gaacagcaat cctgaaacag tttcgactga
    43501 cttttctatt tcggataaat tatattttga gccattgacc ttcgaagatg tgatgaatgt
    43561 gatcgagcta gaacagccga taggagtaat cgttcaattt ggtggtcaga cagcaatcaa
    43621 cttagccgaa cctttgactg ctgctggtgt aaaaatctta gggacaacga tcgaagactt
    43681 ggatcgtgcg gaaaatcgtg atttattcga gcaagcgctg aaagagttgg atattcctca
    43741 acctttaggg gatactgcta caagtaaaga agaagccgtg gttatcgctt cgagaattgg
    43801 ttatccagtt cttgttcgtc caagctatgt attaggcgga cgtgcgatgg aaatcgttga
    43861 aaaccagcga gatttagaag attacatgga acatgctgtg aaagcatctc cagaacatcc
    43921 agtactagtg gaccgttact tgcttggtgg tgaatgcgaa gtggatgcga tttgtgacgg
    43981 tgaaacagta ctcatcccag ggatcatgga gcatattgag cgtgctggtg tccattcagg
    44041 ggattcaatg gctgtgtatc cacctcaaac attatctgaa tcgatcaaga aaacgatcga
    44101 agattacacg atccgcttag cattaggttt gaattgtgtc gggatgatga atatccagtt
    44161 tgtcatccat gaaaatgagg tttatgtgat cgaagtcaat cctcgagcaa gtcggactgt
    44221 tccattctta agtaaggtga caggaattcc aatggcacaa attgcgacga aagctatttt
    44281 gggagagaaa ctaaagacac ttggttatga aaacggactt tatccagaaa caaaagaagt
    44341 tcatgttaaa gcacctgtct tttcttttac gaaattgcag aaagttgata cttacttagg
    44401 gcctgaaatg aaatcgactg gagaagtaat gggatctgac agacaattag acaaagcttt
    44461 gtacaaggca ttcgaagctt ctggattaca cttgcctgaa tatggagccg tattatttac
    44521 gattgcggac gaaacaaaag aagaagcact agaattagct aaacgtttta cagaaattgg
    44581 ctatagtctg ataggaacga aacatacagc tgcttatttc gaaaaaaatg gtctggtcgt
    44641 tgaaacagta gcgaaaattt ctgaggaagc agcagaaaaa aatgtagtcg acttaataag
    44701 agatggtaaa acacaagtgg ttgtcaatac gattgataaa gatcggggaa atgcttctaa
    44761 agacggtttc atcatccgaa gagaagcagt tgaacatggt attccattgt ttacttcttt
    44821 agacacagca gatgcgatcg ttcgagtgat ggaatcccgt gctttttcaa ctaaccctat
    44881 ttaacggcga gcacatgtta agacaaaaag acgaaaaacc gttgcaggag gggacagatg
    44941 aaacaagaaa tgatggaaat cgttcagcaa aaacagctgg caccaaagat ttttgaaatg
    45001 acattgaaag gtgatctagt aaaagaaatg cagcaaccag gacagttctt gcatattctc
    45061 gtgccgcgtg cagacttgct attacgccga ccgattagct tgaatcatat cgaccacgaa
    45121 acaaatactt gccgtatcat ttatcgggtg gaaggtgagg ggactagagt cttctctact
    45181 ctttctgccg gagaccattt agatgtcatg ggtcctttag gcaatggttt tgatttgtcc
    45241 aatcttcata caggagacga agtatttata atcggtggag gaatcggtgt ccctcctcta
    45301 tatgagttat caaaacagtt agtcgaaaaa ggaattaagc caacgcattt tttaggtttt
    45361 gccacacatg aagtcgttta ttatgaaaaa gaatttaatc gtctaggaga aacaagaatc
    45421 gctactgacg atggaacata cggtatgcac ggaaatgtcg gtaatttatt gttaggaacg
    45481 aagacggaac ctacagctgt ttttgcatgt ggttcaaacg ggttattgaa gacagtggaa
    45541 cagctgtttt cttcgcatca aaatgtccag ttatcattag aatcccgcat ggcatgtggg
    45601 ataggggctt gctatgcttg cgtttgtcat acgccggaag atgaaacagg aacaaaaagt
    45661 gtgaaagttt gtgacgaagg accgattttt aaaataggag aggtaattat atgaatgaga
    45721 atcctttagc ggtcaaactt cctggcctag aattaaaaaa tcctatcatg ccggcaagcg
    45781 gctgtttcgg ttttggcaaa gaatacggaa aatactatga tttgaatcag cttggatcga
    45841 tcatggtcaa ggcaacgact ccaaatgccc gctttggcaa tcccacgcca agagtggcgg
    45901 aaacaccatc tggcatgttg aatgcaattg gtttgcaaaa tcctggtcta gacgttgtta
    45961 tgcataaact tcttccagaa ttagaggagt acaatgagtt acccatcatc gcaaatgttg
    46021 ctggtgcttg tgaagaagac tatgtagaag tttgtagcaa aattggcgaa gcaccaaatg
    46081 tgaaagcaat cgagctgaac atttcttgcc caaatgtcaa acatggcgga attgcttttg
    46141 gaacagattc tgatgttgct tttcaattaa cacaagcagt aaagaaagtt tcttctgttc
    46201 ctgtctatgt caaattgtcc ccaaatgtaa cagacatcgt tccaatcgct caggcaatcg
    46261 aagctggagg ggcagatggg tttacgatga tcaatactct tcttggtatg cggattgacc
    46321 ttaagacaag aaaaccgatt ttagccaatc aaacaggtgg actctccgga ccagcaatca
    46381 agcctgtcgc tattcgtttg attcaccaag tagcaagtat atccagcctt ccaatcattg
    46441 ggatgggcgg cgtgcagaca gtggatgatg ttcttgagat gtttatggct ggagcaagtg
    46501 ctgtagctat agggaccgcg aatttcaccg atccgtatat ctgtcctaaa ctaattaaag
    46561 agctccctgt gcgaatgagc gaactaggca tcgaatcgct ggaaagatta atcaaagaag
    46621 tgagagagga acgtgaacga tgaatcaact agaccaacga ccaattattg cattagattt
    46681 ttcaactagg caagaggtag aagactttct tcgatttttc ccgaaagaag aaaaattgtt
    46741 tgtgaaaatc ggaatggaat tgttctacca agaaggacct gaaatcgtac gttatctaaa
    46801 agaggctggt cataatgtat ttttagatct gaaacttcac gatattccga atacggtcga
    46861 aaaagcaatg cggggattgg caaagcttgg tgttgatctc acctgtgttc atgccgctgg
    46921 cggtattcgt atgatggagg cggcaatgcg aggattagaa gaggggactc cagaaggtgg
    46981 aaaacgtccg ctacttctag ctatcactca gcttacttct acaagtgaag aagaaatgca
    47041 tgccgatcaa ctaatcgaag tttctttaga aaaaagtgtg atccattatg ctagctgtgc
    47101 caaaaaagca ggattagatg gtgtggtttc ttctgcttgg gaagtagaag cgatcaaaga
    47161 aatggcagga gacgaatttg tttgcttaac tccgggtata agaccagaag gaacagtcgc
    47221 aggagatcag acaagagtag tcacaccttc tcaggcaaaa aagatcggct caacttttat
    47281 cgttataggt cgaccaatca ctcagtcaac taatccttat aaagcatatc aaacgattca
    47341 aacagaatgg agctaaccta aaatgaatgt tgaacaaagt atcgcaaaag acttattaga
    47401 aattgaagca gtatttttaa atccaagtaa tccttttaca tgggcaagtg gaatcaaaag
    47461 cccaatttac tgtgataacc gaatcacgat gagctatcca aaagtccgaa aagagatcgc
    47521 aaaaggatta gcaagcaaaa tcaaagaagc ttaccctgaa gtacaagtga ttgctggaac
    47581 tgcaacagca ggaatccctc atgccgcatg ggtagcggaa atactggatt tgccaatggt
    47641 ctatattcga agtaaggcga aagatcatgg gaaaggtaac caaatcgaag gacgtatatt
    47701 tgaaggtcag aagatggttg tgatcgagga tttgatttct acaggcggaa gtgtcttgga
    47761 agcagctgaa gcagcaaaaa gagaaggtgc ggatatcctt ggtgttgcgg ctatctttac
    47821 gtatgagttg ccaaaaggaa aagcaaattt cgaaaaagcc gaaatccctc ttatgacgtt
    47881 gaccaattat tctgtattga ttgaagcagc tttagaagat cgttatatcg atgagcaaga
    47941 attaactctg ctaaaagaat ggaaaaaaga tcctgaaaat tggcagattt aagcgcgctt
    48001 gatgaagata gagaaatccg atttgtgtct ccagaatcat caattggaat agcaaaaatc
    48061 caaaaactga ttgcgagaag catcttttca tcaggtatga aaagaaactt ctatcgtgat
    48121 cagtttttga tttttttaaa attcattttt ctaagactgg ttagcagaaa gaagagaata
    48181 atctcttctc ttttttctat tatatataga ttttctctat tttttggtaa gggagctgtt
    48241 tcaaaaatgg taaagagcgg aaatgttgcg aatatcagtt atttaatgat atgatattcg
    48301 gaaaaagaaa tctcaaaggg aggtaacttt tatggggttg aatgaattta ttttaggatt
    48361 gaacaattta gagacgatca caagggcacc tggatttttt aaatatacag agcatacagt
    48421 tgcagcacat tcgtatcgtg tagcatctat tgcgcaagtt ctaggagaca ttgaagaagc
    48481 gaatggacaa ccgatcgatt ggaaactgct ctatgaaaaa tcattgaatc atgactacac
    48541 agagcgtttt attggtgata tcaaaacgcc ggtgaaatac gcaagcaaag agttaagagg
    48601 gatgctgcaa acagttgaag aaaagatgac ggacgaattc atcaaccaag agattccagc
    48661 tgagttccaa gaagtttatc gccgtcggtt gttcgaagga aaagatgaaa ccgtagaagg
    48721 agaactatta gccatttcag ataaggttga ccttctttat gaatcttttg atgaaatcat
    48781 caaaaataac ccggaaaaag tttataagga gatgttcatt gaggcagtga ctacgattaa
    48841 aagctttgaa catcggcctt ctgttcagta tttctttaaa gagatatttc cggaactatt
    48901 gaaccaggaa ttttatggaa aagaggcgtt tttagaaacc gtctcaacga ttgtaaagaa
    48961 agaagaaaaa taaaaatgat atgagatgca gggggaagta tagttgaaaa agaatatgga
    49021 tgtcgaatgg ggctattctg gagacaaagg tccggaaaat tgggcgagtt tatgtgattg
    49081 gtttgcgaga ggtgcggaat ttccattgca gtcgcctatt catttgacca agggggaaga
    49141 aaccaaaata gaaggagaca cgctttcctt tcattatcaa aagcaacggt ttactgacaa
    49201 ggaattcaaa aacacgattc atttagtacc ttttgaccaa ctcagttatg tagagttcaa
    49261 gaaagaacgc tattatttga cagatattca tttccacttg ccttctgaac atatcatcaa
    49321 cggaaaacag gaagatattg aatttcattt tgttcatatg aacagcaaaa aagagaatct
    49381 agttgtgggt gtcatgtacc agctaatggt acaggaaggt tggctgtata atcaagaaaa
    49441 tggggaaagt tggaacttag aaaaacatga gcattgggta aatccggatg tgttctttcc
    49501 ggagcaaaaa agccatttcc attatattgg ctcattgaca actccgccta ccagcgggcc
    49561 aatccaatgg tttgtaatgg atcatgtagg aaaactgaac caagagtttc ttctcccctt
    49621 cgatggtcag tatgctcgac cgaacaaccg accaatccag cccttgaatg gaagagaaat
    49681 ttattatttc gaggagtttg agcaatgaat attcagcaga tgaaatacgt ggtcgctgta
    49741 gcaaacaatg gtagtttcag agaagcggca aagaaaatgt ttgtctccca gccaagtctt
    49801 tcagctggta tcaaagaatt agaaaccgag ttagggatca cgctgtttac tcgaacgaat
    49861 cgaggggcat atttaacaga agaagggcaa gacttcttaa atcgtgccga gaaaatattg
    49921 gtccagcttg atacattaga aactcactat ctaacgagtg aaaagagaga caatttttcg
    49981 atcgctgccc agcattatga tttcttaggt cctttgaccg cacagctact cgaggaattc
    50041 aaagacgaga tcaaacaatt tcggatcatg gagacgacaa cagcgagagt gatcgaagaa
    50101 gtcaaagagc agcacagtga gatcggcatt atttatatga atgagcataa tcaagctggt
    50161 atcagaagat atttacaaca aggagagcta agtggccgca gcattggaaa attcaaaacg
    50221 catatttttt taaggcaagg acatccatta gctgaacacg cagagatcac caaagaagaa
    50281 ttgttatctt atcctcaagt tcgttttaca caggatggaa ataatttccc gtatttttat
    50341 gaagacctta tcgagatccc tgatcaagaa acagtgattt atacgagtga tcgaggtact
    50401 ttgatgaata tcgttcttga aactgatgct tacgcttcag gatctggtat tgtgattgga
    50461 gggattcgcg agcacttgcg gttaatccct ttggcagaag gcgaactaaa tgaattttat
    50521 atcatttatt cggcgaaacg tccgctcagt gaaatcgctc aaagatttat caaagagctt
    50581 actcggttac tggaccagca gagctaagaa aagcagatga gaacgctgtt tattgaacac
    50641 cgttgat
//
LOCUS       DACBZK010000011        48210 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.011, whole genome shotgun sequence.
ACCESSION   DACBZK010000011 DACBZK010000000
VERSION     DACBZK010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48210
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.011"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="IVD66_000720"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="IVD66_000720"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HAP6144964.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="IVD66_000721"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="IVD66_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HAP6144965.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="IVD66_000722"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="IVD66_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HAP6144966.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="hflB"
                     /locus_tag="IVD66_000723"
     CDS             complement(3742..5853)
                     /gene="hflB"
                     /locus_tag="IVD66_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HAP6144967.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="IVD66_000724"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="IVD66_000724"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HAP6144968.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="IVD66_000725"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="IVD66_000725"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HAP6144969.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="IVD66_000726"
     CDS             complement(8053..8523)
                     /locus_tag="IVD66_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HAP6144970.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="IVD66_000727"
     CDS             complement(8569..8994)
                     /locus_tag="IVD66_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HAP6144971.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="IVD66_000728"
     CDS             complement(9061..9330)
                     /locus_tag="IVD66_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HAP6144972.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="IVD66_000729"
     CDS             complement(9341..10936)
                     /locus_tag="IVD66_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP6144973.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="IVD66_000730"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="IVD66_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HAP6144974.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /locus_tag="IVD66_000731"
     CDS             complement(14489..15049)
                     /locus_tag="IVD66_000731"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HAP6144975.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="IVD66_000732"
     CDS             15402..16376
                     /locus_tag="IVD66_000732"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAP6144976.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="IVD66_000733"
     CDS             16546..17946
                     /locus_tag="IVD66_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HAP6144977.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="IVD66_000734"
     CDS             complement(18024..18746)
                     /locus_tag="IVD66_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP6144978.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="IVD66_000735"
     CDS             complement(18825..19331)
                     /locus_tag="IVD66_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAP6144979.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="IVD66_000736"
     CDS             19454..21253
                     /locus_tag="IVD66_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HAP6144980.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21321..22895)
                     /locus_tag="IVD66_000737"
     CDS             complement(21321..22895)
                     /locus_tag="IVD66_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144981.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="IVD66_000738"
     CDS             complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="IVD66_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HAP6144982.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="IVD66_000739"
     CDS             complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="IVD66_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HAP6144983.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24672..25310)
                     /locus_tag="IVD66_000740"
     CDS             complement(24672..25310)
                     /locus_tag="IVD66_000740"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HAP6144984.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25311..25961)
                     /locus_tag="IVD66_000741"
     CDS             complement(25311..25961)
                     /locus_tag="IVD66_000741"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAP6144985.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="IVD66_000742"
     CDS             complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="IVD66_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HAP6144986.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="IVD66_000743"
     CDS             complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="IVD66_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HAP6144987.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29104..29844)
                     /locus_tag="IVD66_000744"
     CDS             complement(29104..29844)
                     /locus_tag="IVD66_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HAP6144988.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="IVD66_000745"
     CDS             complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="IVD66_000745"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HAP6144989.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31215..32153)
                     /locus_tag="IVD66_000746"
     CDS             complement(31215..32153)
                     /locus_tag="IVD66_000746"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HAP6144990.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32146..32637)
                     /gene="def"
                     /locus_tag="IVD66_000747"
     CDS             complement(32146..32637)
                     /gene="def"
                     /locus_tag="IVD66_000747"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAP6144991.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32652..35060)
                     /gene="priA"
                     /locus_tag="IVD66_000748"
     CDS             complement(32652..35060)
                     /gene="priA"
                     /locus_tag="IVD66_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HAP6144992.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35313..35618)
                     /locus_tag="IVD66_000749"
     CDS             complement(35313..35618)
                     /locus_tag="IVD66_000749"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAP6144993.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="IVD66_000750"
     CDS             complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="IVD66_000750"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HAP6144994.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(36724..37008)
                     /locus_tag="IVD66_000751"
     CDS             complement(36724..37008)
                     /locus_tag="IVD66_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144995.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37026..37916)
                     /locus_tag="IVD66_000752"
     CDS             complement(37026..37916)
                     /locus_tag="IVD66_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HAP6144996.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(37936..38154)
                     /locus_tag="IVD66_000753"
     CDS             complement(37936..38154)
                     /locus_tag="IVD66_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144997.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38124..39824)
                     /locus_tag="IVD66_000754"
     CDS             complement(38124..39824)
                     /locus_tag="IVD66_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HAP6144998.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLAKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40090..40863
                     /locus_tag="IVD66_000755"
     CDS             40090..40863
                     /locus_tag="IVD66_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6144999.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(40944..41513)
                     /gene="thiT"
                     /locus_tag="IVD66_000756"
     CDS             complement(40944..41513)
                     /gene="thiT"
                     /locus_tag="IVD66_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HAP6145000.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNSWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(41579..41681)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(41687..42658)
                     /locus_tag="IVD66_000757"
     CDS             complement(41687..42658)
                     /locus_tag="IVD66_000757"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAP6145001.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(42752..44125)
                     /gene="glmU"
                     /locus_tag="IVD66_000758"
     CDS             complement(42752..44125)
                     /gene="glmU"
                     /locus_tag="IVD66_000758"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HAP6145002.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(44628..45446)
                     /gene="purR"
                     /locus_tag="IVD66_000759"
     CDS             complement(44628..45446)
                     /gene="purR"
                     /locus_tag="IVD66_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HAP6145003.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(45613..46437)
                     /locus_tag="IVD66_000760"
     CDS             complement(45613..46437)
                     /locus_tag="IVD66_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAP6145004.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46410..47090)
                     /locus_tag="IVD66_000761"
     CDS             complement(46410..47090)
                     /locus_tag="IVD66_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAP6145005.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47113..48051)
                     /locus_tag="IVD66_000762"
     CDS             complement(47113..48051)
                     /locus_tag="IVD66_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HAP6145006.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
BASE COUNT        13201 a        10456 c         8696 g        15857 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gttttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgt gttctgaatt ctctacaagc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc tcctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatgggat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttatact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatc aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggtcgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttctca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ctctttttga ttaatcattc ttacatgctg acagcaaagt caggggcaaa ccattgaact
    21361 gaaccaactt ttacgctttc gcctggttga ggagcatgga tatattgtcc tccgcctaaa
    21421 gcaatcgcta cgtggtaagt tccgccttgt gacccccaga ataacaagtc tccagctttt
    21481 gcttgagaaa ctgaaatttt tgttccagct gattcttgag gaactgtcca accaccgatg
    21541 tcacgaccag ttacttgcat gtaaacatag cgtgtgaacc ctgagcagtc aaagccactt
    21601 ggatctttac cgccccaaac atatggagta ccaatatatt tgtaagcttc tgctacgatt
    21661 gctgcaccat tcacacttcc agaaggagct ggagcaggtg ttacaggttt tggttgttca
    21721 ggtgttggtg ttggcgttgg agccggagta ctacttcctg tgccgtttcc tgtatcaaca
    21781 ctttgatctg ttgatggtgt tgtaggcgca ggtgttgttg attcttctgt tgttgaagat
    21841 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcactgttgt tgattcttct
    21901 gttgctgaag attcaggcgc tgttgttgat tcttctgttg ctgaagattc aggcgctgtt
    21961 gattcttctg ttgaagattc aggtgttgtt gattcttctg ttgctgaaga ttgtgtagct
    22021 gatgatgatt cttcagtcat tgaagattgt gtagctgatg attcttctgt tgctgagctt
    22081 tgtgcagtag atgaagcttg agtagcttgt gcttcagcct ctgcttgttc gcgtgcttct
    22141 ttttcagctt tttcttgtgc agcttgttga cgagcttgtt ctgctagacg ttgttgttca
    22201 cgaatacgag cttgctctgc ttcagcttct gctttttgac ggttcaagtc agctttcttg
    22261 tcttcagcag ttgcttgttc agcagctaat gaagttttca gtacgttcaa atcagcttgt
    22321 ttagataaaa gatcgccttt ttgagattcc aaagcagctt ggttttcagc taattctttt
    22381 agtttagcat cgttttcagc ttttttgtct tctacagctt ttttatcttg tttttgttgt
    22441 tccatcaagt cgttgtttgc ttttaccatc gttgtcattg cttgaacgcg tccaatagca
    22501 tctgctaatg aatcagcatt caatacagca tcgatgtagt ttgagcttgt gttgcttact
    22561 tgtgcttcgc gtgcttgttt ttggattgta tcttcacgtt tttcaatacg ttcttgtaaa
    22621 tctgcaatgt cttttactaa ttgtgcagat tcttgacgca atgtatcttg ttttgctaat
    22681 aggtcttgtg cttgtgtgtt gatttcagaa acttggcttt ctaaggcatc gatttgtgat
    22741 tgtgcatctg cttgttgatt tttcaagtct gcaatctttt gatcttgctg ttgtatctga
    22801 gaatcaaaat cgtccgccgc ggcagcgatc ggtgatgcta cggcagtcaa ggtcattgaa
    22861 cataccatta ctgctgatat taaactcttt ttcactcttc attcctccga ctggcttaat
    22921 ttaataaata tctaaatata tttaagtctt tcttaacgat ataaaaattg taccatagca
    22981 gtgtgtcaac gatataatag ttatgttaca aaaatgtttc aaaacaactt ttaaaaatga
    23041 caaaactgtt cgtttcagaa aatgatcatg aaaaagccgc gttaagtcta gcatttctta
    23101 agataacaac gattcttttt cgctttcgac ctaaaaataa aaaaagaaat tattcatcac
    23161 tgaataattt cttaaaggga aaaatgaata atacaaatat aatcatgttc aacagcagtg
    23221 taggtcctaa aaaccttgta ataaaatacg tgttatttac tactgctaat ttaaaaatca
    23281 actggaccac catcgtaaac aattcataac ccgtgacaaa gatgatcata ctgaaaaatt
    23341 cagtaaagat gttgacatgg ataacgtctt tcattacata catcaaccat acaattaaag
    23401 ggagagctac tgcatagata ccgataacgc caatatagta agcgtcatag atagccccga
    23461 gaacaatcgt ggtaatcagt aaataacgtt tttcaaacgc catactgcaa cataataatg
    23521 ccaatatcag aaagtgggca tttgacatat aggtgccttt cgaccactcc cctagcattc
    23581 ttgttaaatg accatctatc aacatcaaaa agaacaaaac gattggcaga tagtacttca
    23641 ttgtttcttt cttcaacatg gactaatcct ccgctagccg ttggacaatc gtcacaactg
    23701 acacgtcata catttctgca taaggtttca cataaacttc ccgatccagc ccataactat
    23761 ctggtttcgt tttaataacc gtaccgatcg gcaagttagc tggagaattc cctccaagac
    23821 cggatgtctg gacaacatcc ccttctttga tatccgtatc accagttaat tgggtcacca
    23881 ctaaggcatg gagcttttca tcatagtttt taagcaaacc aaacgcttcg ccattagccg
    23941 aagatacccg tactggaaaa tgattggagc tttcattaga ggatgacagt aattcgattt
    24001 tagacgaagc cgtattgacc tcgatcactc ggccaatcaa tcctttttgc gacatgactg
    24061 ccatatttgc ttcgataccg tctttagaac ccttgtctac gatcagcatg tcctgccaac
    24121 tgtcaggcga acgagtaatg acatttgccg ttactttttc gtaactagtc agcgtctgat
    24181 tcaactcaag ttcttttttc aacgcttcga tttctctctc gtaattcttg ttttgctgtg
    24241 aaacgtcatc atagctatcg attttttctt ttagccgctc attttcggca taagttgaaa
    24301 aaagattatg gacagaatct actccatttc gtacccaccg tactggggca gagattgttt
    24361 tatcaaccat tgcaacactg tcattaacga tggattggaa gaaattgggc tttccttcat
    24421 tcgctcgctg cgcagcggtc acacttagta tcgtcaccac gatgataaca ataaccaagg
    24481 taataataat atttttatta ggattgaact tcttcacaaa gacacctcga attaattaga
    24541 ctcttgtgtt caattttatc actaaatgcc gtgaaacaaa aggtaagttg ctcctcttaa
    24601 gctttttttt agcaaataat agattctgtc atttttagcc tgaaagacaa atttttttat
    24661 ttgtttatgg atcaatcttt gctttgaata actgcaatca taccatctga aaaagaaaat
    24721 tctgcggtat ctgaaagaaa ttcgttactt gcataagatg tcggatattc tacttcttta
    24781 ttttccaata catacttgct gccttttaat gtaagattcg agacgggagt caagcagcaa
    24841 taagctaaat acttcatatc tggtatctgt cttactatat gctctccagg caaataataa
    24901 gacaaataat tttgacaatc tctgataata agctgatggg caaagggttt gaagcgaggt
    24961 tccataccta accagagatt ggctaaaaga tgatccaatc ttccgcccgt agctccaatc
    25021 aaagtgactt ccgcttgcgg gtaacgttca aatgttttta agatacctaa ctgtgtatct
    25081 gtatcgtctt tttctgcagg ggaacgggta tactctttgg cttttgcaaa tacttccttc
    25141 tgctcttcgt tcgacaatga atcaaaatca cccactgcca gatctactgg gtagcctgct
    25201 tgaagcaggt acagcgcacc acggtctatc ccgacatagg catcgtattt ggacagcaga
    25261 gactgcggcc agttttgcgg attacctcca gcagctaata aaattttcat ttagtctaat
    25321 gcctctttta atcgttcgat ttgtccgact ggattttcgg ctccatagat atatgatcct
    25381 gcaacgaaga catccgcccc tgcatcttta cagatttttg ctgtttctgg aacgattccg
    25441 ccatctactt cgattgcata agtccaattg ttctctctac gtagatcagc gagttccgta
    25501 attttttcta ctgtttcttc aataaagctt tgtccgccga acccaggatt gacagtcatg
    25561 actagtactt gatcagccaa aggcaaaaca tgtttgatca tggagactgg tgttcctgga
    25621 ttgataacta ctccagcttt aactcctaag ctttttgtca tttgaagtgc ccgatgaata
    25681 tgaggagttg cttcgacgtg gacagtaatg atatctgctc cagcttttgc aaatgctgga
    25741 atgtagtttt ctggatcaac gatcatcaga tggacgtcta acggtaattt agtaacagga
    25801 cggattgcct gaacaatatt tggccctaat gtgatatttg ggacaaattg gccatccatt
    25861 acatctacgt ggatgtaatc tgcgcctcct ttttccacta actcaatgtc tctttgtaaa
    25921 ttggcaaaat ctgcactcaa aatggatggt gctatcttca ttcttgtttc ctcctatttt
    25981 cgtttacctt ctttttttgc atacattggt tttctttttt cgatttcttg taagaattgc
    26041 aaataattgt cgtaacgtgt ctgtgcgata ccacctgttt ctactctatg ttttacttcg
    26101 cagccaggtt ctttagcatg catgcactct ctaaatttgc aatggacaga agcttctaca
    26161 aattcaggaa attgtctcgg cagttctcct gcttcaattg tcaaaaagtc aatcgagcta
    26221 aatcctggtg tatctgctac taacccgcca tagataggaa tcagttccac atgacgtgtt
    26281 gtatgccgtc ctcttccaag tgcatcagaa atctctcctg ttgctaaatt cagttccggt
    26341 gatatttgat tcagtagcgt cgattttcct gctccagact gacccataaa gaccgatagc
    26401 cgttctggga agtaacggat cagttctgtc gtatcacccg tatgattggg tacaatcacc
    26461 ggatagccta ttttagtata ggtttgcttg atctcttcga ttttttctgg gtcgtctgac
    26521 aagtcggtct ttgtcaaaaa aataatcggt tcgatcgact cgtattccaa ggtaactaga
    26581 aagcggtcaa gtagattata agaaaatgca ggctctacga tacttgtgac aatgattcca
    26641 agatcaacat ttgtgactgg tgggcgaact aattgatttt ttctcggcaa gatttccaga
    26701 agatagccgt ctgtttgatt ttcactctca aagatcacct gatctccgac aagcggcgtg
    26761 attttccgat tccggaaatt tcctcttcct cttgtttgat aggtctctcc gtttgcgtat
    26821 acatagtaaa aaccgctgat tgcttttctg atttgtcctt tgataagtgc cacctccgtt
    26881 tttgtttatt ttaccatacg aagaggaaag taggtgttat tccatgcaaa cttctcaaag
    26941 tatatggctt gaaaattgat caaaagagat agaaacacaa aaaagagaat gcaacaaatc
    27001 aatgtcgcat tcccttctga tatattttat tcagcactta ttttgaactt tctgaggtgc
    27061 tagctgatga acttgtggag ctggaagatt cttcttttga agagttgctt gtgctactgg
    27121 agctacttga gctgctagaa ctgtctgaag agtctttttc agaactagaa gacgctggat
    27181 ctggtccttt agagtaaatt acgttcacaa ccattccttt ggtaattgtc gttcctgccc
    27241 ctggtactgt acgaatcact ttatctttat ccaccgtgtt tgaatattcg gaagtctcat
    27301 gcccgatata ttctgcaccg acactagcta aataactttg tgcttcgctt tttgtatagc
    27361 cggagatatc attcaattta ggctctgttc cttggcttac gacaaaattg atgtaagttt
    27421 cttctgctac aacttcaccc gaggctggat cctgactgat gatcgaacct gatggtacag
    27481 tgtcgctata gtcataagta gcactaatat tattgatatt gaatccttgt gtaacaagcc
    27541 aattacgaac agtttcgtag ttttctccta catgactact caaagtcact gtttctggtc
    27601 ctttgctgac tgtgaaagta atcgtgtctg ttttaggatc gacttctgta tcttctgatg
    27661 gagattgcga aatgatcatt ccgctttcta cctctgaact gaattcctct tctttttgaa
    27721 tcaagtcagc agaaaaccct aattctttca aacttgcttc ggcatcttca taacttttac
    27781 cactgtaatc atctaatttg atttttttcg tgccgctact aatatacaga gtgacttcgc
    27841 gtttttgctt gactgtcgtt cccgctgccg ggtctgtctt cactacatta ccttcttcga
    27901 ttttgtcatc tgcaatttct tctgtttttg ttgctacttc taatttcgct tttgcgagtg
    27961 tttctctagc agaagcttca gaaagatcag aaacatcagg aacaacaact tctcctcgcc
    28021 cgccagaagc aaagaataca gctgttccga ttcctaaaac agcaagaata gctaatagga
    28081 tcagccacca ttttttctgt cctttctttt taggatcagg cagaacttct tcctcctctg
    28141 gtaaggtttc gttttctggc ttgtcttttg gcagaggcat agatttgaat gaatcaggca
    28201 ttggtgcatc ttccgtaagg ggtgtgataa cttttgtttc attatccatc acatgaggct
    28261 gccatttttc ttcgtttgca cgagctggtg ataatactgt agaaagatca tcagacattt
    28321 cctcggctga cttataacgg tctgcaggtt ctttagccgt tgcccgtaaa atcacgtttt
    28381 ccagtgcttg tggcacattt ggatcaagtg cttttataga tggaagatca tcttgaaaat
    28441 gttttaaagc aattgttaca gcagattcac catcaaacgg tacgctaccc gtcaacatct
    28501 cataaaggat gatccctaaa gcataaatat ctgactgctt cgttgccata cttcctctgg
    28561 cctgctcagg ggacagataa tgaacagatc ctagcatcgt attcgtctgc gtgatcgatg
    28621 tttcagataa agcgatagca atcccgaaat ccgtgatttt tacaacacct tcattatcga
    28681 tcagtacgtt ttggggtttc aaatctcggt ggatgatttg atggttatga gctaaagaaa
    28741 tagcagaaag gatctgctgc ataatattta ctgctgtttc ataaggaaca ggataatgtg
    28801 tttggatata tcgtttcaag tccattcctt tgacgtattc catcaccaga tactgcatgt
    28861 tgtcttcttc accaacatcg taaacactaa caatgtttgg atgaacgagt tctgttgctg
    28921 ctaaagcttc tctctgaaat cgtcgaatcg cagtctggtc attttgaaag tcaaatcgta
    28981 agactttaac tgctacatca cgatccaaga ttaaatcgtg cgccaaaaat acatttgcca
    29041 taccaccgct accgatattt ccagtgattt gataacggcc atttaatttt ttgcccaact
    29101 cgatcataca ctgtcctcct tatattcgat aagaagaacg gtgatattat ccgctccgcc
    29161 tgcttcattg gcacgatcaa tcagctcagt tactttatga gacaatgggc cttcttgatt
    29221 gatgatcgtt cctatttctt cttcagacag catgttcgtc aagccatctg aacataacag
    29281 cagtcgatct tttagttgcc aaagatgagt agaaacatct acttcgactg ttccaggcat
    29341 gccgacagaa cgtgttaaaa tatttttcct tggatggttc actgccattt cttcgctgat
    29401 ttctcctgat ttgactagtt cattgactaa agaatgatcc tccgtcaatt gcatgatttt
    29461 atcttcacga atcaaataag ctctgctatc cccaacattg gcaatcgtga accagtcatc
    29521 tgacagagcg gccgctacga ttgttgttcc cataccgtta tattccggct gttcttgtcc
    29581 acgctgataa atcagcatat tttcttcttg aatcgattga atgaaccatt gggcgatttt
    29641 ttcatcgtca acagcttctt gtttttccca agcttcgcct agattcgtta ccgccatctg
    29701 actggcaatg tctccggcac gatgaccacc catcccgtct gctaatacag caagcttgag
    29761 acctgaacgg ctggtaaata cactggcata gtcttgattt gtgttacgtc gtcttcctac
    29821 atctgattga tattcaatct gcattttttc acctcattac tttttgcgca aacaacaaat
    29881 gaaaaatcca tctgtgtaaa actgatgcgg atacaaagtc aacattttct cttcgattga
    29941 tgattgtagc ataggattgg tcaaaacatc aatcctctca aaatcagggt gtctttccaa
    30001 gaaagcagaa acaacgtctt ggttttcttc ttttaagatc gtacaagtgc tataagtcag
    30061 aataccggaa gactttaaag ttggtgcgca gctttctaaa atttccaatt ggatttttgg
    30121 taaattcgct aattcatccg gctgtttttt ataacgaata tctggttttc gccgaagcag
    30181 cccaagacct gaacaaggcg cgtctactaa aatccgatca aactgctctg cttcgaactg
    30241 tttactgact tctctagcat ccatcttttg agcgtagaca gcagaagaga cacctagacg
    30301 tgctgcatta tcttcaatga gtttgacttt gtgttcgtgt acatctaaag cgaccacttc
    30361 tccaccgcat gacggatcta aaaaagaagc aatatgcgtc gtcttacctc cgggtgctgc
    30421 acaggcatct aagacatgat gttcaggctc gatttgcata gacggcgcta caagcatcga
    30481 actttcatct tggatcgtca tgacgccatc gtggaacaat gagctagaag ctaaatgccc
    30541 ttttttcgct actataccgt atggactgac ttggcttttt tcagctgtga tctcttcttc
    30601 ttgcaaaaca gtgatggcct gatctctgga aagtcggcgt gtatctactc gggcactagc
    30661 atggctaggc tgatatagcg ataaaccgag cttttcagtt tcttcgtatc cgatttgatc
    30721 caccagtcgt ttagtcatcc atagaggcag gctgattttg acagaaagtc tttcgatagg
    30781 atcagcaatg ccttgcagat ctggtgctcc ttgacgctga taattcctca agacaccatt
    30841 tacaaatttc cctgtcccag gatttccttt tacttttgcg atttcgaccg cctcgtttaa
    30901 aatagcatgt gcagggactt tatctaaaaa ttctaattgg tatacagaaa gataaagaag
    30961 cgtcttgacc cagtcatcca ctttttttgc tttagcgatc aatggtgcaa cgtaaaattc
    31021 caatagtcgc tgatggctaa tcgtaccata gatcaattct gtaaataaac ccacatcttt
    31081 ttgatttagc tcgctttgtt tgatcatctc attcaacaaa agattcgagt aggcgccacc
    31141 cttgttcact cgctctaatg tcagtaatgc catatatcgt actgattttt tcattttttt
    31201 agggattttt ttcattattt cacctgctga ccaatctgaa cttgctgacc gcttccgtta
    31261 aggaaatcat gtacggcctg ttttccttta ccagctggct gtaattcatt gatggctaag
    31321 acggtctgtt taccgcaagc aatccataga ttttttttgt ctttccggat gatcgtacca
    31381 ggtgctttgt ctgtagtttc tgccaatact tcaaccgata ataatttcca gcgtatgccc
    31441 tcataggtcg tgaatgcaat tggccaagga cgcattccgc gtacttggtt gtcaatttct
    31501 tctgcagttt tatgccaatc gattgcttct tgttcccgtg tgatgtttgg cgaaaaagtt
    31561 gcttctgact cgtcttgagg tactggtttt tgtccatcca aaatattggg caatgtttct
    31621 agcaatagct ttcttcctaa aaggctaagc ttttcaaaca tcgtccctac atcatcttgt
    31681 ttagtgattg gtatgctttc ttgcgcatag attccgcctg catccatttt tttgatcatt
    31741 tccatgatcg ttacaccagt ttctttctcc ccattcatga tggcataatg aacaggcgca
    31801 cctccccgat atttaggaag taaagaagca tggacattga ttgcccctaa ttttggtact
    31861 tgcaataact tttcaggcaa gaattggcca aatgccgcag tgacgatcac atcaggcacc
    31921 aattcaatga tttcttccat ttctggcgaa ccggagattt tctctggctg cagcacacgg
    31981 ataccgtgct tcagagccgc ttcttttacc ggtgtcggcg taattactcg tttccgccca
    32041 actggacggt cgggctgtgt taccactgcc tggatctcgt aacctgattc tatcagccct
    32101 tcaagaatcg gcacagaaaa agcaggtgtg cccataaata ctagcttagt catcaagatg
    32161 ttcctccata tattcttcaa gttcttcttc cgggatctgc tgtatcattt tctcaatgaa
    32221 caagataccg tctaagtgat cgatttcatg ctggaaggca cgggctaaat agccaaaagc
    32281 cgtcacttct atctcttctc cgtctcgatc ataataacgc acggtcactt catctgctcg
    32341 cttgaccgtt ccatagacat gcggaatact gagacaacct tctacgtcaa ggctttcacc
    32401 ttttgcttcg atgatttctg ggttaatcag ttcaaatttc tcgccttcat ctacttcgat
    32461 cacagcaatt ctcttgtttt gtcctacttg aggagcagcg atccctattc cgtcattcgc
    32521 aatcattgtc tcatataaat tgtctaataa agcgattgtc tcgtccgtga ttacatcgat
    32581 tggctgagca gttcttttta atttatcatt agggtggatc aatataggat agcgcataat
    32641 ttggcccttt cttaaataaa gtttaatggt tcgttgtcaa ttgccacaaa aagaccttgt
    32701 cgctgttctt tctggcttcc attcaaaatt tcatccaaaa catgaggaag attcggttca
    32761 tgtttatatt tgatgattag ttgataataa tatcggtttt tcactctcaa aatcatgctg
    32821 ggcgttggcc ctaatagcaa gctttgaggg cttaacactt cttttagctg attggcaatc
    32881 tgaaagattt tctttgccgc tacttgttct tcaggatggc tggcggttat tttcacagta
    32941 aagtaataag gaggatagcc tccacgatgc cgtacatgca tttcctgctg ataaaactgc
    33001 tcataatttt gttttttagc caattctatg gcgtaatgtt gaggattgaa tgtttggatc
    33061 acgacttcgc ctgctttttc cgctcgccct gctcgtcctg aaacttgggt aagcaattgg
    33121 aatgtatgct cactagaacg aaaatccggt aaattcaggg aggtatcagc attcaacacc
    33181 ccaactaatg tcacttctgg aaagtccaaa cctttagcaa tcatttgtgt ccctaataat
    33241 atatctgctt cttttgcacc gaatttttgt aaaatctgtt cgtgtgcccc ttttcttcga
    33301 gtggtatcta catccatacg caaaatccta gcttgcggat aaagttctcg gagttcctct
    33361 tctacttttt gagtacctgt tccatagtag cggattttat tgccgccaca attaggacag
    33421 cgattgggaa taggttcttc atgtccgcaa taatggcagc gcattgaacg tgtatccata
    33481 tgcagtgtaa gagagatatc gcaattagga catggaagaa caaatccaca gtccctacac
    33541 atcacaaaag acgaatatcc tcgacgattg agcagtagga cagtttgttc ttttttgtct
    33601 aatcgatttt gtattttttc ctgcaaatta gcagaaaaag tagaggtccg atgattctga
    33661 aactcttcac gcatatctac gatctcaata gctggaagct gtgcagctgc tttggctcgg
    33721 tggtttaact gcaataactg ataaacgcct ttttgagctc gtgctcttga ttctaaagag
    33781 ggcgtcgcgc ttcctagaac tattgggcaa tgatgatatt tactgcgcca aattgctaga
    33841 tctctcgcat gataacgcgg tgtctcatct tgtttgtaac ttgattcatg ttcttcatcg
    33901 ataatgatca gcccgatatt tttcagcggg gcaaaaatag cagatcgtgc gcctactact
    33961 acttgcgctt cttcccgctc aatcttgcgc cattcatcat atttttcacc ttgggaaagt
    34021 ccgctatgta agaccgcaac tgattctccg aagcgtcctt tgaatcgctc gaccatttgc
    34081 ggagtcaatg cgatttcagg cactaacata atagccgttt tattttctga caaaacatca
    34141 gcgattgcct gaagatatac ttctgttttc ccgctgccag tgattccctc cagcaaaaag
    34201 acctgatctt tttgctgctg acctgctgtg atgatttgtt cgacagcatt tttttgttct
    34261 gcattcagtt ccaatgccgt cgtttggtca aatactcggt ctttataagg gtcgcgataa
    34321 cgttctgatt ctataaactc cagccagccc ttttcttttc cttgattcaa gacagcagta
    34381 ctgattcctt tatttttgaa ataagcaatt ggttcttctt ggctcagttc agataaacac
    34441 aaaagaagtt ctttttgttt cttggcattt tgccgtaatt ttgcccattc ttcttcgatt
    34501 tgcttttcag ttaacaaaga acggaccaaa cgaatcgttt ttactttatt tcgtgtatgg
    34561 acttcatatt tgatatctac taattgctct tggcgccagc gaatcaattg agaaaggctg
    34621 ccttcttctt ctgcttcctt ccaggaaatc acttctcgct gatcaaacaa tacctgaact
    34681 tctggtgtgt ctgccaaagg atagatcaat ttatcatatt ctgctttcat cacactcgga
    34741 agcatcgttt gtagacaagt gattttgaat gcgtaagtaa tttttttcat ataatcagct
    34801 aatgaaagta attcttcatt gaccaccgga gcaaggtcta gcaaacgaat aactgccttc
    34861 aaagatggat tagctgattc ttctgatttt tggatagcca taacaaatcc ttggacatga
    34921 cgattgccat taccaaaagg gacttctact cgcatcccga cttgcaaagc tgtttccatt
    34981 tcagagggaa ccaaataagt gaatggctga tcggtctgca tagtaggtac gtccacaatg
    35041 acttcagctg ttaatgtcat ggttcgtttc ctcctttttt tgtcttttct tatcaagcga
    35101 caaaaagttc cttgcctatt ttactagaga tcgatggatt tgtcttatct tctgccaaat
    35161 cctaacaaaa aattaacagc agataagaaa aaaaagaact gtgtcaaaaa gttcagacac
    35221 agccttttct accagacaat aagtggcgaa tgtttgaaaa ggaaacagct gggtttgctt
    35281 ttctttttag atgttcgctc tatttttctt tattacattt tttgctcttc acggatacgt
    35341 gattccaatt cgtgttgttc acgctctttt tgtgcttgac gttcctcttc ttccatcttc
    35401 aaacgttcac gttttaattc aggatgtgga tcattgacta catttcctgc atcgatttct
    35461 tctaaagctt gaccgacgct ttttactgaa tcaaaagaat ctagagtagg ctgtgcactt
    35521 gcatccaatt catgcgcgcg tttacttgct aaaatcacta gagaatattt tgaatttaca
    35581 cgatctaata gtgagtcaat tgaaggtttt aacatcataa gactacatct cctttaacat
    35641 tttaatatat ttaccgatta cgcgatctac tcgaaaatgt tcactggcaa taatgttttt
    35701 gattcgttca actgctagcg gcacttcatc atttacaaca gcatagtcgt aaagagccat
    35761 catttcgatt tcttcttttg caactttcat tcgttcttcg attacttcat ctgcatctgt
    35821 tcctcggcct acgatccgtg attttaattc cgctaaatct ggcggagtca aaaagatgaa
    35881 tacaccatcg ggcacttttt ctttgacttg ttttgctcct tggacttcaa tctccaagaa
    35941 aacatctttt ccttcatcca atgtcttgtt gacatatgac aaaggagttc cataataatt
    36001 cccgacatat tctgcgtatt ccagcatctc tccagcttcg atcattgatt caaactcttc
    36061 tttgcttcgg aagaaataat caacgccttc gacctcccct tcacgcattt tacgggtagt
    36121 cattgagatc gaatactgaa aatcattatc ctcactctca aaaattgctt ttcgtactgt
    36181 gccttttcct acaccggatg gaccagacaa cacgattaat aatccacgct ctgacatgac
    36241 gacgtccttt caactagtct ttttgtactt atcgtttatt ttgcactttt tttctgcaac
    36301 tttcaaggtt atctttaatt atagctagaa attggtaaaa aagctaccct gtaccaagag
    36361 gtcgtaaaaa agctgtcctg catcaagtaa taagaacagc caaacataaa cagcttctca
    36421 tgtttttcgt ttggttgggg ttattatcgc agatgcaagc ttttgaacgc cgtgtataag
    36481 aggtcgtgaa gaagccgatt agtttcgagt atgaagaaaa attttgtgaa aatagtttct
    36541 cacatttttg cataaatttg gcttaatacc gagaaaatgg tttttgaaca tcacttattc
    36601 aaaataaaaa aagattgtga cacgaatttt gtcacaacct ttaaatgtat tcctagagca
    36661 aagaagctaa gcgaagaaat ccaattctga ttatttattg tatttctttg ttcagcatcc
    36721 ttgctaaaag cccatattgg acaaagtatt cactacaccc atgatctcat cttttcgaga
    36781 acgtgctttt tctgtcggat cttctacctc ttctgtgtca attcgaacaa taaatttccg
    36841 attcatcgtc acgtaagcac cgtcgttgat caaaataaac agttcgttct cattatagtc
    36901 tgcacaggca tctttccata cgtcaaagcc gtttttttca gaagggatat cccgtttaac
    36961 cacagttttt ccacttaatt cgtggaacgt tacgtcataa tatttcatta tctctacctc
    37021 tttcgtcatt caatattttg tacttgttct ctgatttttt ctaagatcgt cttagactgg
    37081 acgacttgat ttttaatttc gattgcattt gatttggaac cgatcgtgtt gatttcccga
    37141 ttcatttctt ggatcaggaa atctaattcc cgacctacag gacattgtgc ttcgataagt
    37201 tcatctagtt tttgtacatg gatcgccaga cgatccagtt cctcgtgaat atctccgcgt
    37261 tccaacaaga tggctagctc cgtcaacaac cgttgctcat cgactttcgc tccaagaaat
    37321 tcctccagct ttttttgata ccttatttga aattcctttt catagatttc tacaaaacta
    37381 tcgagttttt ttagtacttc tttgaattct tcagtattct ttttcaacac taaagctaaa
    37441 gcttgacctt ctttttctcg actcgcctca atagaatcaa gtgcgctttt caatgtatct
    37501 agagctaact gtgccaattc ttccatgctc tcttccggtt tttcttctac cgttacgaag
    37561 ttttcgtcca gcgcgaagcg ttccgccatc cgactaattg acacttgatt ttgactaccg
    37621 tatcgttgtt gaattccgtc tgtcaattga gtgataagtg aatcaatcaa ttcccagttg
    37681 atgacgatct gtttttcgtt tttgccaata taagctagat tcacaaatac ttcgattcga
    37741 ccgcggctta actgctgttt aataagctga cgaaaatcgt tttcaacaaa gttcaggatt
    37801 ttaggacttc gtatttgaac atctagaaaa cgctggttga cactttttat ttcaatatct
    37861 aactgatacg cttttgtttc gcggatggct ttgccaaaac cagtcatact tttcattcga
    37921 cagggtcctt cctcattaca tattttctat tgctttttgc agttgttcaa actcttcgtt
    37981 cgtcaatgtc aggcctttcc ccattttttc atggtctggc gcccaatctc gaagatcgaa
    38041 ttttggcggg cgaccattcc agctgactag gttcagttct ttacgccacc ccttgttgtt
    38101 ttctgacaat atagcgattt cttctacgat ttcatatgaa aattcttgtg ccatggttgt
    38161 tcctccttga gataatataa atataggatc agtaatgtgt caactggttg cttaagcaat
    38221 tcatgctgca aacgatcctt gcgttttcct tgtagcagat aatcaaaata aacagttttc
    38281 gtgcgctcat tttgtatttt ttgctggtat tttcgatacc ttcgccattc ttcagtactt
    38341 aattgaccaa tttgtgccaa taaatcatcc ggcatacttt ttatatcttg ttggcagatc
    38401 atttgaatca tcatgtctac ttgatagatt tcattgggca gtaaaaaatg tttttttgct
    38461 aaaagttcta gcatcgccaa tccgcatgtc tctggtacga ccctgttctt atataaatta
    38521 cgcagttttt gccaaaattt tatgcttttg aaaaaagata attctaactg aatttctttt
    38581 gctaagtaag acaaaaatcc tcgccagtat gttcttgcag gtttaacaga atgaaatgta
    38641 taccagttcc catagtaata gcctaatcgt tttttcattt ccagatagcc taattgtaaa
    38701 tttaattggt tcctttggct atcaaaaagc agaaagctgc ctagtgtcca caatgtttga
    38761 catttccaat ggataaaaat gtctggcata cgaatttttt tcgctgggcc tggcccttgc
    38821 acatctacga caaatgcctc tgttgctcct ttgttaatcg caatatcaat aggtattttg
    38881 ttgcgatacc caccgtctgc atatttattt tttccgatct ttcgataagc catagcggga
    38941 taaaatgaag cagaggcgag tatccaatct ggtatttctt ctgtttttgt ctgttggata
    39001 tcagtcacta cttccgctag ttctggcagt ttagtagaca ccgtatataa acgtattttg
    39061 ggattatgtt tgagtaagga caaatccaaa ttgtctttga ccatcttttc caatggagca
    39121 gaagaaaccc cgccttcaat tagtgctgtt ttcgtcattt ggcgtctttc tcgatagaag
    39181 cgttcacgaa ggtcttcaac tgcagccatt tctggtaacg caagcacttg tcttgtcgac
    39241 agctttttcc ataaattcac agcttttttc atatctcctt gtaaaatcaa tgcgccgttc
    39301 aacgcaccta ccgaggtacc tgtgataatc tcaaagttga tatcatgttc cttcagcgcc
    39361 tgccacacac caatctgata agcaccgtgt gctcctcctc cacctaaaac aagtgctgta
    39421 tgatagacca gctttttatt taattgtgtg gttccttgat agccgttttt atgaaaaata
    39481 cgcaaccatt cttctgatag aggagattga aataaaaaac aacagttttc tttaataaaa
    39541 aaacgagcgc aagcttccat ataccgaaaa aattttttcc attcaaaagt ttcaccttca
    39601 atcaacagat tattaaaaat aacatctcct ctacttttag caatagtaaa atagacggta
    39661 tattttttcg atactgcttt aaaagcacat tgcttttttg cagaacgcca aaaagcgtct
    39721 ctactttctt gatgactttg aaaaaatgga aggggttgtt ttgcttgctg gataggcgaa
    39781 tacagcgaca ttttctgtga aaagtaaact ttttttatct ccatcgcgct ctcctttttc
    39841 ttcaagtata ccagtacgtc ataaaaaggt catgagtctc gtattcgact ttgtagattc
    39901 cataagaaaa caattcataa aacatccttt aaataaaaaa tacaaaaatc acaaaaatta
    39961 attgaaaatg agagtgtttt caatgaaaac gtgattttgt aatggaattt taaaataaaa
    40021 gaaacaagct tttttaatgc aaatgttgta aaataaaaga gattaagagg aaataagagg
    40081 aggaacatga tgactgagtc agtttatgta catattgata ccacaagtaa tgctgtttta
    40141 acaaaagggc tgactgctac tgactttgca aacagtatcg tgcattttcc tcaaaacttg
    40201 ctcttgcttg atccatctgc ttctgctgga gaatatgaat cccatacagg gctgaaagta
    40261 atccgtggta cagaaaatat tcagcgtttc ttttcctctt ctcgtaacag gcgtggattc
    40321 gatgaattga agtggatcga ctttactgat ttaacgatgc tgaaagaatt gacaccttta
    40381 gaaatttcag aattattata ttttggtcat atgaaaacac atcttcattc gccgtttttt
    40441 tataaactac agaataattt tgtatacttc gatcttaatg atcagctgaa tcggatttat
    40501 tatcgctatt tagatgaatt ttataggatt tttgctagta aattaagttc gatcttgtca
    40561 gataagatca atgtaaaaaa atcttttttc aaaaaagaaa cacctgttga aaaaatcagt
    40621 gtggaattat tgaaagaaat gcgtaatttg atgcaggaag ggatcatttt ttcttttgat
    40681 caagttggtt tgatcgatgg taaatatcgt atcccaatct atgtgattga agattatatt
    40741 tggaaattaa aaggcacccg gtatcgagaa gaggaaatca tcgctacttt aatctactct
    40801 gtcaccgatc gacactggca attggtagaa gatgccgatc tttcttatct gccattgaag
    40861 tagatctatt tcttatcaaa aaataaaaag gaaacaagaa actaggacat gattctgtct
    40921 caagtttctt gcttcttttt tatttacagc tcctgtcgtt tatctggcac aaaaatcgaa
    40981 ggagtcgttt gttggatccc taataaaacg atgatcgtta caatagctgt actcaacccg
    41041 ctggcaccat tcattacgaa agaaaagagc caagaattca tcccccatag tgcatacgct
    41101 ccccagaaaa ccactcctgc aataaaatgc caaaaatatc tggaaagtgc gccaatcaat
    41161 gcaccaaaca cgatgctttt tctaatttgt ttcgtattat cgtctacata gcctttttgg
    41221 acatttgaag ccatgagccc tgctgcgcct gcaaaagtat aggcaatcgg gtactcaatc
    41281 aacacttgaa cgacacttaa ataataaact tgtcccaacg gaaaatgtag gatgccccaa
    41341 atgaaacctg ccagcatccc tgcctttgtc cctcttctta acgcaaaaag agtcaatgga
    41401 atctgcccta atgaaataga aaaactgctg ccgatctgga tcggaatcaa cgacaacacc
    41461 atcgctaacg ctgcaacaat cgttccttct acccaaactc tattttttcc cataaaaaaa
    41521 cttcctcctt tgaataaaaa agtcacaaag gaggaagcag ctttcgaaaa tagtcaaaca
    41581 gctgtttatt cacaattcct acgctcgcat aaccgataca ggtacgaagg gtttagaaat
    41641 agattcaatc tcagcccaat tggactcccc tttgtgagtt tatttattat ttattttttg
    41701 tttcaaacaa tggactaact ggtttgtttt catggatacg tttgattgca tctcccatta
    41761 gtccgccaac acttacttca tcgattttgt cgattttacg atcttctgga agatagatcg
    41821 agtctgtaac aactagacgc tcgatagctg aatcttctat tctttgtaaa gcagggccgg
    41881 ataatactgg atgtgtacat gaagcataca cactagttgc accagcttct ttcaaagcat
    41941 tggcagccaa tgtgatcgta cctgctgtat cgatcatatc atcgatcagt acacaagttt
    42001 tgcctttgac ttgtccaatg atattcatta cttctgcaac atttgctttt ggacggcgtt
    42061 tgtctatgat cgcaatcgga gatttcaaaa attccgctaa tttacgtgcc cgtgtgacac
    42121 caccatggtc tggtgaaaca acgacaacat catcgccttt gattcctttt tctaagaaat
    42181 aattggcaat aagtggcgca cccatcaaat gatcgactgg aatatcaaag aaaccttgga
    42241 tttggactgc atgaaggtcc aaagtcagca ttcttgttgc accagctttt tgaatcatgt
    42301 ttgctactaa tttcgctgtg attggttccc gtgcacgtgc tttacggtct tgacgcgcat
    42361 agccataata aggcatgact acgttgattg tttttgcact tgctcgtttc agtgcgtcaa
    42421 tcatgatcag caactccatc aagttatcat tgactgggct gctcgttgat tgaataacat
    42481 agacatgcga tccacgaata ctttcttcaa tgtttacttg aatttctcca tcactaaatt
    42541 gagtaacaga tgattttcct aactcgacgc cgactgctgc tgcaattttc tctgctaatg
    42601 ggcgattgga atttaacgca aaaattttta atcttgggtc aaagtaatgt tttgacatgg
    42661 ggacctccac tttctttttc acaactctag aattctacct aataaatagt agtcatattt
    42721 tttaaataaa tcaagtgatt ttgcaaaagt cttagtttag ataagggagt ttttttgcat
    42781 atccttcttt attgacttgt cttgctctcg caattgccag cgcatattct ggaatattgt
    42841 ctgtaattgt tgacccggca gcaatcgaac tgtttttagc tacctcgaca ggtccgatga
    42901 tattcgtgct agaaccaata aagctgtggt cgccgacagt cgtatgatgt ttgttctttc
    42961 catcatagtt gacgaagaca acaccacatc cgacattgat ttcttctccc agcgtagcat
    43021 caccaacata agtcaagtga ccgactttag ttcctttgcc gatttgagca tttttcactt
    43081 ccacaaagtt tccgatatgg acgttttcgc caatttcagc ttttggtcgt aaatgtgcat
    43141 aaggtcccac atctgcatgt ttcttgacat ggctgctttc aatgactgag ttttcaatga
    43201 cgacgtgatc ctcaatccta ctgtctacga tttttgaatg tgacccgatg acacaatcag
    43261 aaccaatgac tgtatttcct tggatttgta cacctgcttc gatcaatgtg tctggaccga
    43321 tttctacgcc tgcatcgatg tatgtcgttg ctgaatcgac aaagcttacg ccattgacca
    43381 tatgcatctg gttaattcgc tttctcatga tctcatttgc tttagctaac gcgatccgat
    43441 cattgactcc cattgattct tcaaaatcat ccgtttgata agcagcaact gtatggcctt
    43501 cttcttttaa gatttcgatg atatctgtta gatagtattc accttgagca ttgtttgttc
    43561 caactttgct taacgcatcg aacaaagctt cgttgtcaaa acagtaagtt cctgtattga
    43621 tttcttgtac aagagcttct tctggtgttg catctttttg ttccacgatt ttttctacga
    43681 tcccaatatg gtcacggatg attcgtccat atcctgttgg gttttctgct tgtgccgtca
    43741 agatcgttgc acttgcattt tttccttggt gatattcaaa aagattgttc agcgtttcag
    43801 tagtcaataa tggtgtatcg ccactgataa ctaacgttgt tccttttttt ccttccaaga
    43861 aagaagcagc ttgcaaaaca gcatgtcctg ttcccaattg ttctgcttgt aacgcatatt
    43921 tactgcgttc tcctagttgt gctttaactt gttctgctcc gtgtccaacg atcgtaatca
    43981 cttcatctgg tttcgtttca ctgacccgat taatgatatg ttctaccata ggtttaccag
    44041 aaacgggatg taaaacttta tataattttg acttcatgcg ggtacctttc cctgccgcca
    44101 aaataattgc ataacgtgcg tccaactgcg tcactcctaa atatagtttg ctgatttcag
    44161 tttatcccag tatacccatt ttttcaacaa aacaagtgat tttcttttat cccagcgttt
    44221 tctggataaa aaaatagata gaccataacg ggcctatcta tttggtaacc ggtgctctcc
    44281 tgccaactcc tcggtcacaa gtcacactac tcataaaaca tgaaaagctg ttttttgaaa
    44341 tcgtttcttg tgacttagag ttaaacggta ggcttacaac ctcttcatta aacgtttttc
    44401 aatcagctga ccttcggtat tagctcaata aacggcaaaa tatgaggagc aatttttccg
    44461 tttattgagc taatactcag gacaggacgc tgatttcaca acctctagat aaacggtgtt
    44521 caaaagccag tttctcggta ttaagccaaa tttatgaaaa aatgtggaaa gccattttca
    44581 caaaattttt cttactactc gaaactaagc ggctttttca caacctctta ttctgaaaaa
    44641 taatttcctg gcacaaccgt aatatttttc gtttgagtat ctacatcttt gacataaagc
    44701 agtgacgtat aatcatcgat ggcgcgatga ccgttgaatt ttgattcggc aaatacagtg
    44761 atgccaacaa gttctgattc gaattcttca atcaagctct tcattccgtt gactgttccg
    44821 ccgcctttca tgaaatcatc cactacaagg acacgtgaac cacgtttcaa acttctctta
    44881 gacagttcca tcttttcaat tctttcagaa gatccagaca catagttgac acttactgtt
    44941 gatccttctg ttatttttga gtcccggcgt acaataacga atggcgcatt cagataatag
    45001 gacacagctt gggcaatagg tacgcctttt gtggctacag tcattacagc atcgattttt
    45061 tcaccaaggt atttagaagc aatgattctt ccaacttgac gcagcagttc aggttctcct
    45121 aacaaatcag agagataaac atatcctcct ggaagcagac ggtcttgttc tgatagacgt
    45181 tctgctagag attcaatata ttttttcgcc tcttcatatg aaatttcagg gatgaacaat
    45241 acaccacctg cagcacccgg gattgtttcc aaggttccat accctcgttc tttaaatgtt
    45301 ttcttgatga ttcccaaatc ttcactgata gaagatttag cagattcata acgttcggca
    45361 aagcttgtta aggaaatcaa ttcatgcggg tgattcaata aatactgtgt catgtcaact
    45421 agacgttcac tgcgacgtac tttcacctat tccaactcct tttaagaaat tttatcgttt
    45481 tacattatat aagtttttct tcaaaaattc gagcatttta tgaaaaaata agaaaatagt
    45541 tcggtattta ttaaaataaa aagaagccta taaaaaattt ttcgttttta taaggcttct
    45601 tttctttata atttagttat tttttcttct gaaggcaacc aatattcgtt tgatgatatt
    45661 tacaatcagg aacaaagcaa taaagactaa tgtgattgtt gctcctggag gtgtatctag
    45721 ataaaacgag ctagttagtc ctgacagcat ccctagaaat cctacacaaa cactgatagc
    45781 aatcacgaca ttgaagcttt tgcctaatcg cataccgatt gctgcgggaa gaaccatgat
    45841 tgcggatatc aaaagtgcac cggcaatcgg gatcatcaca gcaatagcca caccagtaat
    45901 cacattgaac atcatcgaca tcaaatgaac gggtagccca tccacgtggg cggtatcttc
    45961 atcaaaagtc agaacataca tcggccgttt gaataaaaag aacaatatac cgatggcaac
    46021 gaataagatt cctaaaaaga tgacttgctc ccatgtaatg gtcacgatcg aaccaaacag
    46081 ataggattgg atacttgttg ctgaattccc tccgctcaaa ttcatcaata ctaacgctag
    46141 cgccaaacca ccagccatta aaatggcaat ggagatttct gaataggttc ggtagatcgt
    46201 tcgcagatac tccaatatca cagctgctaa tacaacgact agcatggtcg taagtgtagg
    46261 attaaggttc aaaaagaatc ctaacgctac ccctgctaaa gagacatgag aaagcgtatc
    46321 agccatcagc gattgtcttc tgatcactaa aaacacacct agcatcgggg cgattccggc
    46381 aatgaagata gcggcaagaa acgctcttct catgaattca tatgaaagca acgccattga
    46441 gaatcctcct ttctcaccag tcggatctgt ctgtccgcat actgtttgat atcttcatga
    46501 tcatgggtga tcattagaac tgatttccca tggacatgcg cactatgtcg gagaagacga
    46561 taaaattcat ttctggattc ttcatccata cctgttgttg gttcatcaag aacaaataag
    46621 tcagggtcag tagcaaaaat acgcgctaaa ctgattcgct gcttttgtcc gccagacaat
    46681 tcacctattc gccgatttcg catatcccac atccctacag cttctaaagc acgctgtaca
    46741 tgttgatgat ctttttcaga gagacgcttg aaccagcggc ctcttggata tcttcctgaa
    46801 cggactaatt cgatcaccgt actaggaaaa cctgcattga aagatgcaac ttgttgagga
    46861 atataaccga tacttaattt ttttccttct tgatttttct cagcaatctt tatcattcct
    46921 tttgaaggtt tcagtaatcc taacgatgct ttcaccaagg ttgacttggc tgctccattt
    46981 tctccagtta aaatgacaaa ttcacccgca tctacatgat aagagacatc ttctagtaca
    47041 ggttcatcat catagtaaaa ggtcaaatca gatatttcga tataacgcac cttacaacct
    47101 ccattctaaa acttaattga tactttcttt taaagctttc agattttttt ccatgacaga
    47161 aatataattt tcgcctgctt tgatttgttc attagtcaag ctttctaaag gattcaacac
    47221 ttctagcttc actcctgttt cattcgacaa tgtctcagct accttcgaag aggcattttc
    47281 ttcaaaataa atcactttga tgttgttttt cttcacaaat tcttttagct cagctaagcg
    47341 acttggtgtg ggttcctgat ctggtgaaac gcccgaaatc gctacttgtt ttaagtcgta
    47401 ttgattcgct aaataagcaa aagcagcatg ctgagtgaca aatgtgcggt ttgttgcatc
    47461 ttttagctca tcggagtatt tttgatccag tgcttcaagc tttttgatat aagcatcggc
    47521 attcttcgta aaagtttcct ttttatctgg atatttttcg cctaattctt cagcaatcgt
    47581 tctgacttct tttatagcta ataccggatc gagccaaaca tgtggatcgt attcatgtga
    47641 atgaccatgc ccttcttctg attcttcatg ttcgtctgct tcttgcgatt ctaaacggtc
    47701 gattccttta gctgcttcga tcatcaaggt ctgtttgcta tccactgaat cctttaacga
    47761 atccacaaaa aattccatgt ctgaactatt atacacgaaa acatctgcat cggaaatttc
    47821 tgctctttct tttgcacttg gttcgaaatc atgcggctcc gttccagcag ggatcaaaag
    47881 tttcacgttt ccttcatccc ctacgatctc ttttgtaaaa tcatacatcg gataaaaagt
    47941 cgtaacgatc gtcaaatcct cttttttgtc tgcttccttg ttcgtatttc cacatgctgc
    48001 aaacagtaaa gcacctatca ttaccgtagc tgtcaaaaga tattttttca tttatatgct
    48061 cctttcaatg aacaaatcgg aattttacga tttattaacg tgaactaatg tatcaaaata
    48121 aaaaaacaca gtcaatagaa atccatcaat ttctgattta agcatgtata ttcttgatta
    48181 aatcgtaaaa tggatgagtt gctgctcata
//
LOCUS       DACBZK010000012        47992 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.012, whole genome shotgun sequence.
ACCESSION   DACBZK010000012 DACBZK010000000
VERSION     DACBZK010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.012"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(22..1806)
                     /gene="pyk"
                     /locus_tag="IVD66_000763"
     CDS             complement(22..1806)
                     /gene="pyk"
                     /locus_tag="IVD66_000763"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HAP6145007.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(1880..2842)
                     /gene="pfkA"
                     /locus_tag="IVD66_000764"
     CDS             complement(1880..2842)
                     /gene="pfkA"
                     /locus_tag="IVD66_000764"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HAP6145008.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(3010..6324)
                     /gene="dnaE"
                     /locus_tag="IVD66_000765"
     CDS             complement(3010..6324)
                     /gene="dnaE"
                     /locus_tag="IVD66_000765"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HAP6145009.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            6555..6740
                     /locus_tag="IVD66_000766"
     CDS             6555..6740
                     /locus_tag="IVD66_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HAP6145010.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(6802..7998)
                     /locus_tag="IVD66_000767"
     CDS             complement(6802..7998)
                     /locus_tag="IVD66_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP6145011.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(8168..9604)
                     /locus_tag="IVD66_000768"
     CDS             complement(8168..9604)
                     /locus_tag="IVD66_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAP6145012.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            9897..10706
                     /locus_tag="IVD66_000769"
     CDS             9897..10706
                     /locus_tag="IVD66_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP6145013.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            complement(10892..13045)
                     /locus_tag="IVD66_000770"
     CDS             complement(10892..13045)
                     /locus_tag="IVD66_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HAP6145014.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(13440..14288)
                     /locus_tag="IVD66_000771"
     CDS             complement(13440..14288)
                     /locus_tag="IVD66_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP6145015.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(14512..16452)
                     /gene="thrS"
                     /locus_tag="IVD66_000772"
     CDS             complement(14512..16452)
                     /gene="thrS"
                     /locus_tag="IVD66_000772"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HAP6145016.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(16789..16968)
                     /locus_tag="IVD66_000773"
     CDS             complement(16789..16968)
                     /locus_tag="IVD66_000773"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HAP6145017.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(17015..18838)
                     /gene="cadA"
                     /locus_tag="IVD66_000774"
     CDS             complement(17015..18838)
                     /gene="cadA"
                     /locus_tag="IVD66_000774"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAP6145018.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            19116..21395
                     /locus_tag="IVD66_000775"
     CDS             19116..21395
                     /locus_tag="IVD66_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6145019.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(21488..22135)
                     /locus_tag="IVD66_000776"
     CDS             complement(21488..22135)
                     /locus_tag="IVD66_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145020.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(22314..23033)
                     /locus_tag="IVD66_000777"
     CDS             complement(22314..23033)
                     /locus_tag="IVD66_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP6145021.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(23164..24315)
                     /locus_tag="IVD66_000778"
     CDS             complement(23164..24315)
                     /locus_tag="IVD66_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAP6145022.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(24532..25272)
                     /locus_tag="IVD66_000779"
     CDS             complement(24532..25272)
                     /locus_tag="IVD66_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP6145023.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(25276..25599)
                     /gene="rsfS"
                     /locus_tag="IVD66_000780"
     CDS             complement(25276..25599)
                     /gene="rsfS"
                     /locus_tag="IVD66_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HAP6145024.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(25656..26249)
                     /locus_tag="IVD66_000781"
     CDS             complement(25656..26249)
                     /locus_tag="IVD66_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP6145025.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(26233..26880)
                     /locus_tag="IVD66_000782"
     CDS             complement(26233..26880)
                     /locus_tag="IVD66_000782"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HAP6145026.1"
                     /translation="MNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHLV
                     MAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIELA
                     RGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPGY
                     TTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(26893..27204)
                     /gene="yhbY"
                     /locus_tag="IVD66_000783"
     CDS             complement(26893..27204)
                     /gene="yhbY"
                     /locus_tag="IVD66_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HAP6145027.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(27220..28329)
                     /gene="yqeH"
                     /locus_tag="IVD66_000784"
     CDS             complement(27220..28329)
                     /gene="yqeH"
                     /locus_tag="IVD66_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HAP6145028.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(28326..28853)
                     /locus_tag="IVD66_000785"
     CDS             complement(28326..28853)
                     /locus_tag="IVD66_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HAP6145029.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(29033..29818)
                     /locus_tag="IVD66_000786"
     CDS             complement(29033..29818)
                     /locus_tag="IVD66_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HAP6145030.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(29811..30680)
                     /locus_tag="IVD66_000787"
     CDS             complement(29811..30680)
                     /locus_tag="IVD66_000787"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HAP6145031.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(30681..32060)
                     /locus_tag="IVD66_000788"
     CDS             complement(30681..32060)
                     /locus_tag="IVD66_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HAP6145032.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(32068..32487)
                     /gene="fabZ"
                     /locus_tag="IVD66_000789"
     CDS             complement(32068..32487)
                     /gene="fabZ"
                     /locus_tag="IVD66_000789"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAP6145033.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(32512..32988)
                     /gene="accB"
                     /locus_tag="IVD66_000790"
     CDS             complement(32512..32988)
                     /gene="accB"
                     /locus_tag="IVD66_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HAP6145034.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(32991..34226)
                     /gene="fabF"
                     /locus_tag="IVD66_000791"
     CDS             complement(32991..34226)
                     /gene="fabF"
                     /locus_tag="IVD66_000791"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HAP6145035.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(34245..34982)
                     /gene="fabG"
                     /locus_tag="IVD66_000792"
     CDS             complement(34245..34982)
                     /gene="fabG"
                     /locus_tag="IVD66_000792"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HAP6145036.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(34994..35911)
                     /gene="fabD"
                     /locus_tag="IVD66_000793"
     CDS             complement(34994..35911)
                     /gene="fabD"
                     /locus_tag="IVD66_000793"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAP6145037.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(36018..36242)
                     /locus_tag="IVD66_000794"
     CDS             complement(36018..36242)
                     /locus_tag="IVD66_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAP6145038.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(36295..37257)
                     /locus_tag="IVD66_000795"
     CDS             complement(36295..37257)
                     /locus_tag="IVD66_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HAP6145039.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(37267..37707)
                     /locus_tag="IVD66_000796"
     CDS             complement(37267..37707)
                     /locus_tag="IVD66_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP6145040.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            38013..38978
                     /locus_tag="IVD66_000797"
     CDS             38013..38978
                     /locus_tag="IVD66_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAP6145041.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(39035..39265)
                     /locus_tag="IVD66_000798"
     CDS             complement(39035..39265)
                     /locus_tag="IVD66_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HAP6145042.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(39351..40238)
                     /locus_tag="IVD66_000799"
     CDS             complement(39351..40238)
                     /locus_tag="IVD66_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAP6145043.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(40327..41550)
                     /locus_tag="IVD66_000800"
     CDS             complement(40327..41550)
                     /locus_tag="IVD66_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP6145044.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(41567..42646)
                     /locus_tag="IVD66_000801"
     CDS             complement(41567..42646)
                     /locus_tag="IVD66_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP6145045.1"
                     /translation="MLYYISEGGRKVKVLLYFESEKMLAKSGIGRALDHQKRALTEVG
                     ISYTLDEKEDYDILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQL
                     SPIVKKYLVGLYQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQ
                     KFREYFKLSPDQKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIR
                     KIVKEDHPENVLFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVR
                     DIPVYNGWLEDSKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEE
                     LKNVYESVLNEKVSSKLKKVNQVKD"
     gene            complement(42777..44504)
                     /gene="ptsP"
                     /locus_tag="IVD66_000802"
     CDS             complement(42777..44504)
                     /gene="ptsP"
                     /locus_tag="IVD66_000802"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAP6145046.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(44504..44770)
                     /locus_tag="IVD66_000803"
     CDS             complement(44504..44770)
                     /locus_tag="IVD66_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HAP6145047.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            45249..47483
                     /locus_tag="IVD66_000804"
     CDS             45249..47483
                     /locus_tag="IVD66_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAP6145048.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQKAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            47631..47951
                     /locus_tag="IVD66_000805"
     CDS             47631..47951
                     /locus_tag="IVD66_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAP6145049.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
BASE COUNT        13688 a        10309 c         8401 g        15594 t
ORIGIN      
        1 tttatttttt attaagctaa attagatagc tgttgtttcg ccacggtaaa cgatgccgcg
       61 acgtgaatca acggtaatca attcaccttc tgtaattgtt gttgttgcgc ctttagcacc
      121 aacgattaca ggaatatctt gtgcaattcc tacaactgca gcgtgagaag tcaatccgcc
      181 ttcttcaacg ataacagcag ctgctttttc gattgcaggc atatattctt tgtcagttga
      241 tggtacaact agaaccattc cgtcttttgc tttttttaca gcttcttcag cagatgaagc
      301 aataactgca tttgcaacga cagatttttg tccaacgcct tgagcttcta ataatttaga
      361 accaatcatt tgaattttca tcacgttagt tgttccgcgt tcaccaactg gtacaccagc
      421 agtgatcaag attaaatcgc cttctgatgc gaaacctaat tcaacagctt ttttagctgc
      481 tagttcaaac atttcatcag ttgttgatgg tttttcagca actgttgggt aaacgcccca
      541 gtttaacatc aaaccacgtt ttgtgcgttc gtcaaaagta acagccaaga tatctgcatc
      601 tggacgatat tttgaaatca tttttgcagt gtatcctgat tcagttgcag caacgattgt
      661 tttcacgcct agattttttg cagcacgagc tacagataaa ccgattgttt cagttacatc
      721 tgttttatcg aattcgttca attggaatgt acctaattct gataatgcat tttcagcttc
      781 ttggtcgata cgtgccattg ttgaaacagc ttcaactggg tagtccccgt ttgcagattc
      841 accagatagc attgttgcat ctgtgccatc aaatacagcg ttagcaacgt cagaagcttc
      901 cgcacgtgtt ggacgtgggt tttcttgcat tgattctaac atttgtgtag cagtgataac
      961 tgggatacca gcagcattac attttttgat aatgcgtttt tgaaccattg gtactagttc
     1021 agctgggatt tcaacaccca tatctccgcg ggcaatcata acaccgtcag aaactttgat
     1081 gatttcgtca atgttgtcga taccttcttg agattcgatt ttagggaaga tttgaacatg
     1141 agtcatgtct ttttcttcta agatttcgcg gatatctaga acgtcttgtg ctttacgtac
     1201 aaaacttgca gcgataaagt cgatatcgtt gtctaaacca aaacgaatat cgtcagcatc
     1261 ttttggagta atacctggca aactaataga aacgcctggt gcatttaccc ctttacgtga
     1321 tcctagcata cctgcatttt taacttctac gactaattca cggtttgctt cgtctttttc
     1381 aatgatttgc atatcgatca aaccatcatc aaataaaatg tgtccgccaa cgtgaacatc
     1441 gtcaaataat cctgggtaag taaccgcgat tttttctttt gaacctacat gttcaggatc
     1501 catagagatg cgtgtttgat ctcctacttc aaatttgatg tatcctgcac gaccaaaatc
     1561 agcttctgtt gtgccttgaa cagttgtacg gatttcagct ccttttgtat ctaaaagaat
     1621 accgacatct tttcctgtct ttttaactgc ttcacggacc atagtcatac gtgataattg
     1681 ttcttcatgg tcaccatgag aaaaattaaa gcggaagaca tttgccccag attcaatcaa
     1741 ttgagaaata atttctactg agttacttgc tggtcctaat gtactaacga ttttggtttt
     1801 tttcatttaa aaaactctcc cattcaattt tgtttattta aagctgtaca cagcttaaat
     1861 agcttggttt ctttcactct taaaatgaaa gtgaattatt tagatcatat agtgataagt
     1921 ctggtttatg tttgttgttt tcaagtgtat caatgatgtc agacgcaacg atttcgttgt
     1981 catggatacc gacacataat ccaccttttc cttcttgaag caattcgaca gcgtaagcac
     2041 cgaatttact tgccaacacg cggtcgcgtg cgcttggtgc tccaccacgg acaacgtgtc
     2101 ccaagataga tacacgtgta tgatagtcac caaattctga aagtttctca gcgaattcat
     2161 ttccgcccat tacaccttca gccaagatga tcaagcaatg tttcttcccg cgatcgcggc
     2221 cttcttggat ttttttagca actgaagcca tatcaaaatc atgttctggg atgatgattt
     2281 catccgctcc gccagccaca cctgaccata aagcgatgtc tcctgcattg cgtcccatta
     2341 cttcgataac gaatgtacga acatgagaag tcgctgtgtc acgaatacgg tcaattgatt
     2401 ctagtactgt attgattgct gtatcaaaac cgattgtgaa atcagtccca ggaatatcat
     2461 tatcgattgt tccaggaata cctactgctg ggaaaccgcg ttttgtcaaa gccattgcgc
     2521 catgataaga gccgtctcct ccgataacca ctagaccttc gattccgaat tttttcaatt
     2581 gttcgattcc ttttaattga ccttcttcag ttgcaaattc tggataacgt gcagaataca
     2641 agaatgtacc accacgttgg atcttgtcac ctacatctgc cacatcaaga cgacgaatat
     2701 ctccagcaac taaaccggca aaaccataat tgatcccgta tacttccagt ccttcgtaaa
     2761 tacctttacg aacaacggca cgaacagctg cattcattcc aggtgcgtct ccgccactgg
     2821 tcaaaattcc gatgcgtttc ataataaaca ttcacctcat taaaatactt tatcctaagt
     2881 atgacttagg tttacaacca tttttgcgtt aaccacgact aacattctaa cattattttt
     2941 ctcacttgtc ttgatttacg gataaaaaaa tgaaaaaaaa tgaaagcaag tagtattttt
     3001 taccgtaagt tatttgaaaa ccacattatc ttcgccaagc agataaataa gttgcccctt
     3061 tatactcttg ctgtcatcca cccaataagc atctgacaga actacttttc gttgcgtttt
     3121 ttcgtgatac ataactactg gtatatatcc tgggtgtttc tgaaaaatca cttgtaattg
     3181 tttcattatc tcgggatctt cccgttcttc tgtaatacgc aaatagcaag tttgtgaagg
     3241 atactgggct tctaactggt taggatcagc aaagctttct ccaattagtt gcagttcctg
     3301 attatatttg ctgatttcgc tccgcccttg aacaaagatc actcgatcaa cggcaaacaa
     3361 attacgatat ttacgataaa gagttggaaa aactgtgaca gaaatttctc cactactgtc
     3421 ggttccttca acaaaggcca tcagttctcc tttttttgtc cgaatttctc taacttcctt
     3481 gatcatcact aataaattga ctggttgatt agggacgata tctgtaatca gctgaacttg
     3541 tttagctaaa cgaagacgat caaacccttc tgcaggatga cctgacaaat aaatacctaa
     3601 gtactcctct tccagcttca agcgttcttc tagtgtatag tcagcgactt cttcttcttt
     3661 taatgccatg attcccagca agtcaagact tccaccactg taaacgatat tttggatttt
     3721 tccttcgaga tcaagcatca attgtttcct gttaggagat aattcatcaa aaactcctac
     3781 tgctgtcagt gattgcagta actctaattt cagccaacgc ttatcgatcc gtatgaggaa
     3841 ttgatccact gactggaacg ggccattttg ttttctttcg tttaatatat cttctacaaa
     3901 atcacgccga atacctttta tcgctgtcag tccgaatctg atttcttcct tattgaccaa
     3961 ctcaaaactg gaattacttt gattaatgga cggcgaggaa agtttgagtt tatttttacg
     4021 tgcttctgca atatattctt tcaattttga tgtgttatgc cgaacagaat tcatcaggct
     4081 ggtaaagaaa gcacctggat gatgggcttt tagatacgcc atttggaatc ccacgaatga
     4141 ataagcaaat gcatgtgacc gattgaatcc atagtttgca aatttttcga tatattcata
     4201 tacggtcgct gctgtttttt ccgaatatcc ctgttgtaat gctcctgata caaaatgcga
     4261 cttttcttca tctaatacgt cttttttctt tttactcact gcccgtcgca gaatatctga
     4321 ctgccctaat gtaaatccag ccatagtcga ggcgatctgc atgatttgtt cctgatagac
     4381 gatcactcca tatgtgtttt tcaaaatcgg gatcagtgaa tcatctgggt agcgaatggc
     4441 ttcttttcct ttcttcctgg caatgaaggt atctatattt tgcatagggc ctggtcgata
     4501 caatgcattg actgcggcaa tatcttcgat gttttctgga tctaatcttc gtaaaacgtt
     4561 ccggatacca gcagattcaa attgaaatac tcctgaggtt tcgcctcgtt gaaacaagag
     4621 cagcgttttt gcatcattta gcgggatctc ttttaatcgg atctcatacc cttctactcg
     4681 cttaacagct ttcaaagtaa aatcaataat cgataagttg cgtagtccta aaaagtccat
     4741 tttcaaaaga ccgattgctt ctacctcatt catcgtatac tgggtcagaa aagcttcatc
     4801 agaaccgcgt tggagcggaa ctagttcaag tagattctta tcgctgataa ctacacctgc
     4861 tgcgtgagtc gaaacatgtc ttggcaatcc ttctaaaatc actgcagttt tgaataaaag
     4921 ttggtttttt tcgcttgcct gaactaattc tactaattga tgcgaagttt tataagcttg
     4981 ggtcaatgtg attttcaatt gattgggtat tgcttttgac cagcggtttg cttcactttg
     5041 cgataaacca aacactctag ctgcatctct aagaaccatt tttgctgcca ttgtgccaaa
     5101 tgttgcgatt tgtgccatat gatattgtcc atacttttct cgaacataat tcaatacttc
     5161 ttcacgtcga ttgtcaggaa tatccaaatc gatatctggc atcgtaaagc gttcggggtt
     5221 taaaaagcgt tcgaacagca aatcatattc taatggatcc acatctgtga tttctaacac
     5281 ataggctact aatgaacccg cagcagaacc acgacctgca ccggtaacga ttttgtttct
     5341 atgagcaaaa gccattacat cccatacgat caagaaataa tcatcgaatc ccatttgatg
     5401 gatgacagat aactcgtagt ccaaacgttc ttggtattcc tttgtatagt cagtgattcg
     5461 gcgttccact tgcgaatagc ataactctct taaatattct ccagcttgtt ttccattagg
     5521 aactggataa tgcggaagta atttctgatg gaactggaat tcaaatgaaa tcgattcagc
     5581 taaacgctgg gcgcctatta cagcttggga aagacccgct ttttcgaatc gtttgatcat
     5641 ttcttgttct gaaagaagat agacatttgc tgttagtggt aaagatgcag ataaattttc
     5701 taaaggtatt tggcttccct ctttgatatg tttcatcact tcaagtgcaa aaagttcttc
     5761 ttgttgtaaa ctagcgatgg gatgtaatgc acaaagcgaa taattttctt ttatcacata
     5821 ctgataccat tcaggcaatt gatcaggcgt gttttctgtc aagccgatat aaaaatttct
     5881 agtaaaaaca ttttcaagta aaaactgcca atgaccgaaa aagttatcct ctttattgaa
     5941 agcctcagaa acagaatgat ttgccggaac aacaaacgct agatggtcgg tttctgtcat
     6001 ttctgcaagt tccaattttt cttggatcat ttttcggctg gaaagtttca tcagctgctg
     6061 ataacctatt tcatcttttg cgtacgcaag caagccataa tttttttctt cataagtata
     6121 actaagatgt aatccaatga ttggctgtac tccttcttct acacaaatac gatagaattc
     6181 aggtgcaccg tataagacat ctttatccgt tatggctaat gaagtgtagc cttgtttttt
     6241 tgcttcttgt acatattctc gaatacgtat cgtactttgt aaaagagaat aagaagtaat
     6301 tgtataaagt tgtgggaaaa acatcttgca ttccgccttt tttttcgtta aaattcacta
     6361 gcgttaaaag gtttgatcct tttactttca ttaagatagc aggcgctgaa gttgattatt
     6421 ccacttcatt tgcttgcttg taatctgtag gaatgagttc tttcgcaaga actcaaattt
     6481 tattgagatt tggtctcgtt tctttacatt caaagaaaat ctggtaaaat taagatagaa
     6541 aagaggtgtt ctttatgcga tatatcgtta cattattctg ggctgtcgtt ctaggtcaag
     6601 tagtcggtta tattggtgct gcattaacaa gcggaacata tgattttact ttgacaacaa
     6661 tcatttcatt cattgcgggt gtcattatcc ttttgattgg tgcagttgcg ccaagaaaag
     6721 aaacctctgc ccattcgtaa aaaaacagcc aagagcttga gatttctcaa gctctttttt
     6781 attttctact cctcaccacc attataatct gctgcgaaga actttacgaa agttgaataa
     6841 agaaagaaga atatttgaca gaacaaacaa acttgtcaca ataaaaacag cactgtaatt
     6901 ataagcatgc gcgactgtcg atcctagcat gggacctaaa acttgtccaa agttgctaaa
     6961 catctgattg tagctataga ttcggctgac tccttcttga ggcgtaatct tactgatcag
     7021 tgtattgaca gaaggcatca aagcgccagt tgaaaagcct aaaataaagc gaagtatacc
     7081 taattggagc ggtgtagtga cgaatgccat aggtaaataa cagcaaaatg ataaaatgag
     7141 tcctccaatt agaacttttt gattcccaat cttatcccct agttttccta gtttcggtga
     7201 agaaaagaca gcggaaacac cagctatcga aacaatcaag ccgctgacaa aaaggatatt
     7261 ttctgtactt ccgctcaatt cacgaatata taaggtcaaa atagggctga tcgtagtgat
     7321 tcctatctgt aaaatcaagg tcgtaatgaa gagaccgatc aaaatagaga gatgatccat
     7381 ttttgaaaaa atttctttgg tgcttatcag atcttttttc tcgattggat ggaaatcttc
     7441 tttgactaag aaaatggtca ataccgttgt gatcatcaac aaagcccctg tgatcaagaa
     7501 tacattttcc ataccaaacc actgagccag tgcaccgccc attgaaggtc cgatcagatt
     7561 tccagcaatc gctccggtag acaatgttcc taacgcccat ccgctctttt ctctaggtgc
     7621 ctgtgaagca atcatcgctg tggcatttgg aatatatcca gacaaaatcc cattccaaaa
     7681 ccgcatgatc aaaagccaat acgcgtttgg tacaaaagcc aaagatccca ttgttaatgt
     7741 catccctgct gctgcacgga tcatcatgag ttttcggcct tttcgatcag ctagatttcc
     7801 ccagattggt gcaaccacgg cagatgcaaa agcagtcaca gagattgcta gtcccgaaaa
     7861 caattcgatt tgatcttttg gtgttcctag ttgctcaaca taaactggta tgaatggcat
     7921 aactaaacta atacttgcac cagtgaaaaa acagccaatc cacgcaatca ctaaattttt
     7981 tctccaatta atctccatct atcatccctc tttcgtctct tttatcatac ctattttcga
     8041 ataaacaagc aacgatctcg ccagtaaaaa gagaaaaatc ccgcaaaggt cattttatat
     8101 gtaacgttct ttttatgtaa aacaaaaaga gatcagaaca aatactgttc caatcccttc
     8161 tctttagtta aattgttgct agaatgatga agttgataat gaataaaata tcaacgatcc
     8221 acaaagcaac agaaacttga ttgtattttc ctttgattac tttcacaatt gtatagaaaa
     8281 taaatcctgc tgcaatccca taggaaatgc tatagcacaa tcccataaag atcgatgcaa
     8341 agaaggccgg taaagcttct tccatatcta gccatttgat gtctgcaaaa gaagccatca
     8401 tcattactcc aactaaaatc aatgctggcg cagttgcttg atttggtaca atggcgatca
     8461 gtggagagaa taaactactt aatgcgaata gcactgccac tactactgaa gtcaaaccag
     8521 tacgtccacc ggccccgatc ccagctgcag attcgacata agttgttgta ttcgatgtac
     8581 caaagatagc ccccacagaa gtagcgatcg catcggcaaa tagtgcttta tccatttttg
     8641 ttttgaaccc acgaccatct tccaacgcga tctcgtcttc ttttgagaaa atacctgtgc
     8701 ggcgtcctgt accgataaat gttccgatcg tatcgaaagt atcagataaa ctgaatgcga
     8761 tgatcgtcat caatacttga ggaatcttgg aagaatcact gaataaagat tgcatgcctt
     8821 cagaaccaaa tgctgcaccg aaagttgttc ctaattcttt aaatgaatta cctaacgaat
     8881 tcgtttgcca atcaatggaa cttaaatcaa caacacccat aaaaatacca aggactgtgg
     8941 tcgctacgat accgataaga atagccccac ggacattttt tacaactaaa atggctgtca
     9001 gtaccaaacc aatcacagcc aataagatag gagcgttgtc aaagttggct aacgcaggga
     9061 cgattccacc atttatcgta acatttgtcg cttttccgcc ttcaacgaca gagctcgaaa
     9121 tagctgactg gtctgctgaa aaagataaga atcctgcatt tttgattccg acatacgcaa
     9181 cgaaaatacc gatcccgcca ccaatcgcat gttgaagact ttcgggaatc gcccgaataa
     9241 tcatttttcg aatatttgtg acagtaataa aaatattgat taatccgcaa ataaacacca
     9301 ttgccaaggc ttgttgccaa gaataaccaa gcccaaaaac gaccgtaaaa gtgaaaaatg
     9361 cgttcaatcc cataccaggt gcctgagcat atggtacatt tgcgaacaat cccattacca
     9421 gcgtaccaat aatcgatgca atgattgtcg ctagaaatac tgcttggaag ggcatacctg
     9481 atgctgacaa aatcgtcgga tttacgaata agatataact catggcaaag aatgtcgtta
     9541 ctcccgccat tatttcagtt gatacatttg tattgttttt ctttaaaccg aaaaactttt
     9601 ccataaaaag ttccactccc tgaatttttt tctgatggaa aactataata ataaaaaata
     9661 agtaaaatag ggcaaatcca tcgaacaatt tcaaattata tagacgtttc attcgctttt
     9721 caacgttttt ttaacaaaaa aagcgaaaat aatacttaac gttcgtgttt agcttatgtt
     9781 tagctattta tatagccata actgtagttt ttgttaggaa tagctgattg ctcttgttaa
     9841 ttacctaaaa tatgctagac taaaacaaat gctagttgag gaaggaagga cccttattga
     9901 ataaaaaatt aattgccatc gatctggacg gaactaccct caatcaagat tcgatgatta
     9961 catctaaaac aaaagagact ctaaaaaaag caatcaatgc cggtcatcat gtcagtattg
    10021 ctacaggacg cccattccga atgagccatc agttttacca acaattagaa ttaacaacac
    10081 cgatggttaa ttttaacggc gcattagtac acatccctaa tcagcactgg gatggtgaaa
    10141 gagaaacgtt gatcaatcgt gaaatcgctt ttgaaatctt atcgcaaaaa aagcagctaa
    10201 atttagattt tatcgctgct gaaaatcgtg atactttttt tattgacagt tttgatttct
    10261 ttgatgaaaa aatttttgct tcttctcgtc caggagagaa gaatttgctt tctcctaaaa
    10321 atttgacgac aaatcctaca tctttgcttg tccgaacaga caaacgtttt gcaggagctg
    10381 tatctgctga attaacacgt caatttggca gttatgtcga tgttcggaca tggggtggac
    10441 ctactgccat cttagagatt gtttcaaaag gaatccaaaa agcaaaaggc gtgcaagaga
    10501 ttgctaacta cctgtctatc gatcaaaaag acgtcattgc ctttggtgac gagcataatg
    10561 atttggaatt gttggattat gcaggttggg gagtagctat ggctaacggt actgaccaac
    10621 tcaaaggcat tgcaaatgat gtcactcctt tgagcaatca ggaagacggt ttagctgttt
    10681 atctggaaaa actacttaaa ctataataga gaattagatt ccacaaaaaa gaggttgtga
    10741 caatttttgt cacaaccttt tttgccgagt aaacggtgtt caaaagccag tttctcggta
    10801 tgaagtcaaa tttaagcaaa aatgtgagaa gctattttca caaaattttt cttcatactc
    10861 gaaactaagc ggctttttca cgacctcttt tttattttgc catgaacata tcataatacg
    10921 cgtccattat ttctttagca atcgtcaagt ttatgtggtc ttgttcgtct aataagttcg
    10981 gcaagacaac actgatggca atttccggat tgtctgttgg tccgtatgcc acgatattac
    11041 tattgactgt cgcaatatct ggatgacctt ccgcaaccgt ttctgcagtc cctgtttttg
    11101 cggaaaggtc cattttcgca ctggctaatg gtttggctgt tgtgtaagga tcggtaccat
    11161 ggacaacttg gtggaatcct tcacggagga tcgccatatt ttctgcagaa atattgaccg
    11221 tattttctac tgttgtgcca atttctttct tcacttcacc caagtttcca ttttcgtcat
    11281 tgccatagat cgctttgact aggtgcggct gtactcgttt cccgccatta gcgactgttg
    11341 aagcatattg agctaattgg attggtgtat atgtgtcaaa ctgtccaaat gccaaatcgg
    11401 taaagttacc tggagcatac cattctttgc cattatccgc attgaacttc ttcatataat
    11461 caacagaacg tgagatccca ggagattcat tcggcaaatc gatcccagtc gttgtaccaa
    11521 gaccaaactc tttgaaagag tctctcaatt gctgataagc tttagcttct tcatctaaac
    11581 taggtagtcc cattccaggt gtatagtcta gtcctaacat ctttaacgcc actttgatca
    11641 tatacgtatt agaagacaat tccgatgctt tgactgcatc aagagcaact tgtccgcttc
    11701 gattaaagac agagcttttt tctgaagcac cttgcagacg aatcggctca tcaatcaaaa
    11761 cttgatttcc gctgatcgcg ttacttgccc agcctgctgt caaagtacca gccttgacta
    11821 cagaccctgg atcaaaggcg ctagtaatcg tgcctaaagc attctcggtg atttctttgg
    11881 aaccttgttc atgactgaaa ccagtcattg ctagcacttc tcctgtctga ggattcatag
    11941 ccactgcata agcaccaggc gaatactgtg ctttgccgtt gttgatcaat gtttgataat
    12001 tccttttcaa aatttcttct acttttgatt ggaattctgc attcatagat aacattaaat
    12061 tagaaccttt ttccccagag aagatttctt tttgattcga aacatttcct tcattatcaa
    12121 gggaaacttc atattgggtt ttggttcctt gcaggacatc ttcatattgt ttttccaaat
    12181 aactttgtcc tacacggtca ttccgagaat aaccttttgc taggtatttc tctgcttcat
    12241 ctgctggaag tccttgcttt tcagtcgtca cactgccaag aatacttttc agtgaacttg
    12301 ctgcattata ttctcgtgtc cagtctgtgc cagtcgaaac tcctggaagt tcagaagcgc
    12361 gttctgccac aacagctaac tcttgatcag taacaccaga gtttttgata tagacagtgt
    12421 ttaattcata tgcactattc atccgtttaa agatggtagc aatttttaat tgctcctcgt
    12481 ttaaattaat ctcatcagct gtgactttat tgaccatcgc actatattgt tcgctgttcc
    12541 ctaattgctt ttcttttgcc gaaagtcttt ttgtggcttc tttcaaatgt ttgggatcag
    12601 ccagccaaaa atctttttta tctctatctg tcagattttc atctaccgga acatcgatca
    12661 gcgagttcag cttcgttgcg atttcaagca aatctttagc cgtaacttgt gttcctctcg
    12721 tatatgtgat ggcctgattc gctttattcg taactaaagc ttttcctgtg gagtcgtaga
    12781 tcattccgcg aggagtactt tcttggaccg taatcgtaga agtagacttc actcgcgcct
    12841 ccatctcttc gccgttcacg atctgcaaat aacccaatct agcaatcaac gcaacaaata
    12901 acgtaaatat aatgaaaaaa agaaaattta agcgaaaagg aacatgggac cggcgaaacg
    12961 ttttgttctt aggttcttgt gcaccttttc ttattttttc taaccaagaa gtatttaata
    13021 tttttttcat aaaatctttc atcatttcct atccttccgc ctatttacat tcatgcttca
    13081 ttgtacccaa aaacttctta ataaacaaga agtatttaat atttttttca taaaatcttt
    13141 catcatttcc tatccttccg cctatttaca ttcatgcttc attgtaccca aaaacttctt
    13201 aataaaaaag aaaaaatggg cggagcaaga aattctttac ctaatttcaa gataaaatca
    13261 actttttgtt tcacagcaat cacttaaagt tacatatcca actatttttt tcattaaaaa
    13321 ataaacttat ttttgaaaat tatgttttct taagtcgtga aacactttga tggatcattt
    13381 atttgtggaa aactacgttt tgttattcta aaaaacttat ataaaaaata gtaaggtttt
    13441 tatttcgaat ccataaaata ttcttggatt gcttctcgtg tttttttcac tttttcgcta
    13501 agcttttcgt ttttagccat atagaaataa aaaatgatat cgatcgtagc aaattgggcc
    13561 aaaagtgaat tagttgccgc acttcgattc gtgatttctt ttggtctaga tgtttgtacg
    13621 agtacatcgg ctatcttgct aagcgggtta tttccaaatt gcgtcaacgc aatgatttcg
    13681 atattcatgc ttttcgccag ctcggctaat gcgactacat ctgcacttct acctgagttt
    13741 gaaacaagcc aaagcacttt ctttttctca ttgctgacaa gttgcgggag caagacgtgg
    13801 atatcttttt caaaaatgat tggcttaccg acacgagacc atttttgcag aatatcttct
    13861 actactaaag aagaggcgcc aaccccatat aaaaaaacag tctctgccga ttccaaacac
    13921 tctacgactt tttggatcgt ttcttcttct agaatatcta ctgtttcttt tatcgctact
    13981 tgtgcattgt taccaagttt gtttttgata gagtaaaagg actcatttgc ttctatatca
    14041 ctaaaacctt catcgattcc agtctgtagt tctgttgaaa tcgtgatttt gaagtccgtc
    14101 agactttgaa aaccgatttt tttggaaaaa cgtacaactg tcggcgcact caacccggaa
    14161 gcttctgcta attcattagc tgtcattgta gggaccttct caatattacc gataatgtag
    14221 ttggccaact ttttttctgc tgaagaataa tcttccatca tactttcaat acgactaatt
    14281 acgctcataa gttcctccac ccttttaatg atagtctatg taagtatacc atatcagacc
    14341 cttattcacg gtcgtatact ggataaaaaa caaaaaaaca atccgcccaa cagaatatct
    14401 tatcccatca atcccacaga ttctattgag catctgtgtc tttgaggaat acctgttatc
    14461 tattgttcgg attgctttct atctactact tttttacagg aaatttacct attagttttc
    14521 tctgctgtaa tttttgactt ctgcttccat agcatcaata aagatattca aatcttctac
    14581 agctgtttct ttacttccat aacgacgtac gttcactgtt gcatcttcca attccttgtc
    14641 tccaacaact aattggtaag ggatcttttg tgtttgagag gcacgtatct tatagcccat
    14701 tttttcatta cgatcatcaa cttctacacg caaccccttc atttgcaaac gttctttgat
    14761 ttcataagca taatcgccat gtgcatcaac agaaacaggg atgattgttg cttgtatagg
    14821 tgccaaccat gttggaaaag cgcctttgta tacttctgtt aaataagcga caaaacgttc
    14881 cattgtagaa acaattccgc ggtggataac tactggacga tgcgtatttt ccccgtcttc
    14941 tccaacatat gtcaaatcaa agcgctctgg caataagaag tctaattgta tagttgataa
    15001 tgtttcttct gtaccaagag ctgttttgac ttgaacatct agttttggtc cgtaaaaggc
    15061 tgcctcgcct tctgcttcaa agtaatctag ttctaattca tccatagcgg ctttcagcat
    15121 tgcttgggct ttttcccaca ttgcgtcatc atcaaaatat ttatctgtat tgtttggatc
    15181 gcgatagctc aagcggaaac gataatctgt aatattgaag tcagcatata ctgccaccat
    15241 caattcaagc gtacgtttaa attcatcttt gatttgatca ggacgaacaa atgtatgacc
    15301 atcattcaac gtcatttctc gtacacgttg taaacctgac aaagcacctg atttttcata
    15361 gcgatgcatc attcctaatt cagcgatacg aattggtaat tcacgataag aatggatcgt
    15421 gtttttgtag accatcatgt gatgagggca gttcattggg cgaagaacaa gcatttcgcc
    15481 atctcccata tccattggcg ggaacatgtc ttcttgataa tgatcccagt gtccagatgt
    15541 tttgtacaac tcaacatctc ccattattgg tgtatataca tgttggtaac ctagactaac
    15601 ttctttgtct acgatataac gttcgatcgt gcgtcggatt gttgcccctt ttggaagcca
    15661 gaatggcaaa ccagaaccta cttctgggga aaccatgaac aagtcaagtt cttttcctag
    15721 tttacgatgg tctctttctt ttgcttcttc acggagacgg atatattctt tcaaagcttt
    15781 cttgtcaaaa aaggctgtcc cgtatacacg ttgcatcatt tgattgtttg agtttccacg
    15841 ccaataagca cctgccactg ataataattt aaatacttgt atacggccag tggatggaac
    15901 atgtggtcca cgacacaaat cgatgaattc gccttgttga taagcagtaa tcacttcttc
    15961 ttctggcaat tcactaatca gttctacttt gtacggatca cttgcaaaaa tttctaatgc
    16021 ttcctgtttt gaaagaacac ggcgttcgat cggcagattt tctttgacga ttttcatcat
    16081 ttctgcttcg attgccggca aatcttctgc agttacttgg ttttgtccat tatctgtatc
    16141 gtagtaaaac cctgaatcga tagctggtcc aacgccaaag tggatatttg gatagaggcg
    16201 acgcatggct tgggccatca aatgagctgc tgaatgacgg actaagccaa gtgcatcttc
    16261 atggtctggt gtgatgatct caatacttgc atcttcctcg attggacgag tcaaatcaac
    16321 gagttttccg ttcactttac cagctaaagc tttttttgct aagctttttg aaatgctttc
    16381 agcaattgcc aatgttgttg ttccagactc aaattctttg actgcaccat ctggaaaagt
    16441 aatttttatc ataatagttt cctccttgaa atgttttgat tgatcagatc atcaagctga
    16501 aaaacaaaaa aatcctagca tctcttgaaa agagatacta ggacgaaaag ttcgtggttc
    16561 cacctaatgt tcaaacgcaa atgcgttcct caagcgttgt aacggtccga ccgcccttgc
    16621 ttcaacaagg gtttcgaaag tggtcatcct ttggttttct cctggaaaag tttcagccta
    16681 gcttttcctc tcttatcgaa gactctcaaa ttcagttggc tttctcatca atcaattatg
    16741 tgtttattta accactaata aatagaaaaa tcaagtggga aactaaactt attttttcca
    16801 ttccccattt acaccgtatg ttcctttttt catctcattg atgatgacat ggatgtgttc
    16861 ttttggtgcc tgcgtgtttt tatgaacagc ttccgtgata tctttcatca tattttctaa
    16921 ttgttccgga ctgcgacctt ctactaattc gacatgtacg aatggcataa tgctctctcc
    16981 tctttctgat cgttcttttt tcaactcgat tctatcatac tatgtttgtc ttgggtactg
    17041 aatcaggaaa aatggctgga tctttttttg ctctcaaggc actcaaaata gagaccgtat
    17101 ccacgacttc ttgcaaaaca gctccgaata atgcggggat tagtcccgta cttgcaatta
    17161 acatcaaaaa aatacaaata aagatgccaa tcagtacaga ctgtttcgct attctcatcg
    17221 tatctcttga aatcactact gcttttgcta cacgcaagag atcatctttc aagatgaccg
    17281 catctgcact ttcactagca gctgtagaac catgagcccc cattgcaata ccgatatctg
    17341 cagcagcaag tgctggtgcg tcattcacgc cgtctcctac catcgcaaca ggtctttgat
    17401 ctttagggat actttctaaa atggtcagtt tatcttgagg caagctacgg gcatgtacag
    17461 aatctaattg gactttttct gcaatcgttt gagcaatggc agatccatcc ccggtgatca
    17521 tcatcaaatt tttcacatca agttttctta gctccttgat tgtctttgct gcttctgggc
    17581 gaatctgatc cgaaaatagg atcgttcctg caaaagatcg atcaattgtt acatagattg
    17641 ctgtattgga cgtttctatt tcttcagctg aaacaaaaga ggcacgtcca atctttactt
    17701 catgattatt gactactgct tggattcctt gaccggtcac ttctttcagt tgactaacag
    17761 gatacagttg gctgtttttc acgttgttca ctaacgaacg agctaagata tggctagatt
    17821 cctgttctgc actagctgca tacagaagta gctcttcttt ttttattcca ttgactggct
    17881 gaatcgcctc tacttccaat atccctttgg taagcgttcc tgttttatca aaagcaatcg
    17941 tttttgtacg tgcgagcttt tcaatcgttg ttccagtttt tacaacgatc ccgtttttac
    18001 ttgaacggct cattcctgca actaaagcaa tgggcgcagc tagaatcagt ggacaaggtg
    18061 atgccactac cagtacctca gcaaatcgta aagggtcttt tgagaaccac caagaaatac
    18121 caccgatcaa ataagcaatc aacgtgaaag ggactgcata acgatcagct aaacggacaa
    18181 atcgggcagg cttttctttt gattcttcga ctagtttaat aatcatttga tactggctgt
    18241 ctgcggcacg tttttcagcg atcatttgga tcgatccgtc tccatttaaa gaccctgaca
    18301 taatctgatc tccaggtttc ttggtttccg ggcgggactc acctgtcaaa gaagattcat
    18361 cgaccgaaga ttctcctttg gtcactcgac catctgcggg tacaagttcg ccaggcttga
    18421 ctagtaactg gtcatcaata tttatttcat cgattactat atcctgcaat tttccttctt
    18481 tgaatcgatg ggcaattctt ggggtgttat ctaacaaaga ctgcagttct ttacccgctc
    18541 gtttattcgc gtaatcctct agactatctc cgcccgtaag catgatcaat atcatcaaac
    18601 tagcccagta ttctttgacg gctaatgttg caaggattgc ggtaatcgct aatacatcta
    18661 cgccatatct tcctgaacgt aacgtcttga tcatttccaa aaacatcaag aaggcgagaa
    18721 tccctccagt aaatgcgaca atcgcaaatg caagggccgg ctggtgaaaa acaaattcac
    18781 ttaataaagc tatcccacca ataagcaaag taagtaaaaa ttttttgaaa tgtgtcattg
    18841 ttttttctcc tcttttatgt gacttagaga ggttagtaat aaatttccag ctgcctcttt
    18901 catcttaagc atagtccttg actagcactt tttaaaacaa taggccttaa ttgaaaacaa
    18961 ctatcactat cagcgtttcc aaaattcatc agttctacaa acaaaaatat tcagcaagga
    19021 ttactttttc gattcatcag ttaaaaagta ccttttttcg aaaaactatg ctatactttt
    19081 aattcgttat ttacggcgga aggagcaaac atgcgatgaa tgagaaacaa ctagaacaaa
    19141 cgcacgtgga tgaaacgatc gaactaatcc agatcgaaca aaatatgctg gatacaaaac
    19201 aacaagaatt gactcaggaa atgaatcatt cgacaaaaga cacagctaat cacaagattc
    19261 gagctggttc caatgaagct ttttatgaat ctgctgttga atatcgccaa catgagcagg
    19321 aattgctttt gaaataccat actcttgaag cacagcaaaa acgcctgcaa acgttgtctg
    19381 tcatgaaaga tagtccttat tttgcccgta tcgactttaa agaagaccgt gaaacagaaa
    19441 cattatatct aggtatcgct tctttaagag atctggcaga agaaacaatc gttattgact
    19501 ggcgcgcacc aattgccaat ctttattatg aaggtgagat tggtcccgca ttttatgaaa
    19561 ctgaaacaga tagaatagat gtcgatctgc agttgaaacg acaatttaaa atccaagaag
    19621 gacgtatttt atctatggta gatacgtcgg aagtaatcaa tgatgacttt ttgctagaga
    19681 tattggatga atcatcaagc aaccatatga aaaacatcgt ctctacgata caaaaagcac
    19741 aaaatgcaat cattcgggac acaacaagta aagtaatgct gattgaagga atcgccggaa
    19801 gtggaaagac atccgctttg cttcaacgta ttgcttttct gttgtatcat aatcgcaagt
    19861 ggctcgaggc tgaaaacgtt cttctatttt cacccaacca tttgttttct gattacatct
    19921 cgactgtatt gccttcatta ggtgaaagcg gcgtgcctac acagacattc aaaaattatt
    19981 tggtgcagct gctgccagag ttttctttac tagatgaaca gcaacaagaa agtggttttt
    20041 tgctagggga aaaagatccg atacaagtga tgaaaagcgg attgacctta gtcgatcaga
    20101 ttgatcgcta tatccaaggc atcacaaact acggtccctt gttccgtgat atgaaaataa
    20161 atggccgtac gatcctatca aaggaatcga ttcgccaatg gtataaagaa acaaatgaac
    20221 aattaccttt acatcataga ctttctctat tacaaacgaa gctcctgaaa aaattaggcg
    20281 gtctgcaaaa agacgaaaca cgtcagcaat gggtcaaaga tctggcggaa gaacagctcc
    20341 aagaactata cgcaacagat ccaaatcttg aatatacaga acaaaaggag cgttcattac
    20401 gtaaaaaact ggccaaccaa atcgtacgta aaagattccg tcgaatccat cgagggatca
    20461 tgaattatca atttgtcaat ataacgaaac aatatctcca ctttctacaa actgtgccac
    20521 tttctcttct aacacgacat aaaatcagcg agaccaggtg gcaggaacat ttgacaactg
    20581 ttcgtacaca cttgcgtcaa agagaattgc gtcaagagga tgctgtacta ttctttttac
    20641 tgatgcgccg aacatatcca gtgacggtta cacacaaagc tcgctatatc tttattgatg
    20701 aaatgcagga tttcgcacca tcacaagtgg cattgctgca agccttgttc ccaaaagcaa
    20761 atttgacttt ctgtggagat ctaaatcaaa atgtctttgg aaatgaaacg atcgttggat
    20821 cattggaaga ccttttcgtg gaccgtgaag tcactcgttt ccaattaacg acaagctatc
    20881 gctccacaaa agaaatcact gattttgcta atcattttat tgtgaaagaa catcaagtag
    20941 aaacaacagc aagaaaagga gaccttcctt tgctcatcca aggaacaaca gatgatatca
    21001 aattgaattg gttagcagat accattcgaa cgactcaggg aaaagcccgg tattggcgta
    21061 cagcaatcat agctaaaaca caagaagaat gcgaagctct ttatgctcaa ctgccagacg
    21121 agttgaaaca acaagtccag ctgattttaa atgagagtga ctttatgaag cgttccatta
    21181 ttttacttcc agccttttta gcaaaaggtc tggagtttga ccgagttttc ttgtgggatg
    21241 tagatgcaga acatttttct tctcagcaag acaaattgat cctttacacc atgtgtacac
    21301 gtgcgatgca tgaattgacc ctttttacct ccaataatga aagtcctttg ttaaacaata
    21361 tggatatttc atcttatgag aaaaaagtac tgtaagtaaa aagacaactg ctatcattaa
    21421 tgttagcagt tgtcttttta tttacaataa taattgcaga aaaagtaatt caatcattta
    21481 aggtcattta ttctatatat aaatccaaat ctgtttcagg atattttaat ttgacaagcg
    21541 aaataatcat tttcagttct tccatgtttt ctggatattc tgggtcaaat accttgctat
    21601 gacggccaat cccgccattg tcgatcaatc ggtaaattcg attccattca atgaattggt
    21661 caattgattg gaaattgctg attggatagc cgccacaatc caaaatctct gatacacgaa
    21721 atgctaggta tgcactatcg atcactttat tttttttcgt gtctatcttc tcatttcttt
    21781 cgataagaat tttttcagga cgatgtttca agctccactc taatagtaga aagaaagcct
    21841 ccatccgata ctcttcttca aataaccgaa aggctgaatc agaacgacga aaaagcagcg
    21901 gaatcagata attttgtcta taaatcagca ttggtgcgcg gtccaccata cactctaaat
    21961 aacggttcag ataccctgta ccgacatagt ttcctaatcg atagccttca acgccgaatc
    22021 ttgcgtattt ttgcgctaat tttgaacaat cagttacgtt cacagctaac tcttctactt
    22081 tgcggtaacc gcttaagata cgttcaaaag gttctaaagt gatttttgct tccatattct
    22141 tccccgtcca tcttccacat acttcatatc atttcacatg atacttatgc tctcatcata
    22201 ccacaggttg aattagaaaa gaaaataaat cacacaaaaa agcaagacaa tctgttagtg
    22261 agattgtctt gcttttcgaa aaagactgaa tacttttcgt taaaactggt tgcttagtct
    22321 tctaatgcca cattatggaa cacatgctgt acatcttcta gatcttccag tgcatcaatc
    22381 attttttcaa atgtttcttg atcttctgga gatagtgtta cctcgttttg agggatcatt
    22441 tggatctcag cgattgaaaa atcagtgatt cctttttctt ttaatgcttc ttgtatacta
    22501 tggaaatccg ctacttcacc gtaaacgatg atttgtcctt cttcttccat tacatcgcga
    22561 acatcgatgt ctttttccat taggtattca aggatctcgt cagcgtcttc tcctgcaaaa
    22621 gcaaagattg ctgtattgtc aaacatgtaa gaaaccgctc cggaaacacc catgttcccg
    22681 ccatttttcc caaatgctgc ccgtacgtct gctgctgttc gattcacatt gttcgtcaat
    22741 gtatcaacaa tcaccattga gccgcttggt ccaaatcctt catagcgcaa ttcagagtat
    22801 gtttcatctc ctgcaccttt tgctttttcg attgctcggt caataatatg ttttggtaca
    22861 ttataagttt tagcgcgatc aatgacgaaa cgtagttttt ggtttgcatg cggatcagga
    22921 tcacctgatt ttgctgccgc gtagatttca atcccaaatt ttgcataaat ccggctatta
    22981 ttagcatctt tagcagtttt ctttgctacg atatttgccc atttacgtcc catattttca
    23041 cttcgctttc tgatttgata gtttcataac gcaaaaacgt cctgttccat tatacttgtg
    23101 aatcacgatt ctgtgaagct ttttttcttt cttccttcat tcttctcatt tttagtcaat
    23161 tatctatact cggattggga tttgcccgaa attctgttcc ggaatattgc ctcccaattg
    23221 atagatttga tcacttctaa ctaacagttc cgcttcttgt gcctcttttt ttccgattcg
    23281 ggaataaata gaaatctctt ttttttcttt taagaatctt cttccagcat cggtaaatcc
    23341 aagtagtcga agataatttt tattttgttg gacaggaatc tcttgctttt tgatattcag
    23401 caagacataa caagataatc gttggatccg tgtccatgta tatctttttg tttttacctt
    23461 tgacacaaaa tcctcaaaac tatcagcagt tgcagctgct gttttcatgc gcgattctat
    23521 tccttcggtc atctgataga tatctgtcag ttccagcaaa gtagaagata acaaccgata
    23581 acgcaaatac ggccaataag attcccaagt ctgcagcgaa caagttgaaa gatcttcttc
    23641 tgtctgaggc ggcacaagtc cagctattct ttttccttct tctaacgcat ggcgaatggc
    23701 tgttgcactg gctatcctct gatctgtgat gattttttca tgatagcctg cacttttacg
    23761 tcggatcgga tgtaattcca tagggtggac atacttggca ttttcctttg cataacttaa
    23821 tcccaagata tgatttggcg aagaaaaatc aagcgtaata tcgggataca gactgcgaaa
    23881 aacctcagtc attttttgcg gataactata cgtttgatca gacagttctt gaaatgcctc
    23941 ttctatccta tcttgattct cttggacaaa gcgtccgaaa ctgctgtaat caaacgaagt
    24001 ctcttcttct gttccaaaac acaaactgtc acagtccagt gtttgcaaga tttttactgc
    24061 acctttagca aaatagtcag ctgactgaac cgcccattcg acgggaagct ccactactaa
    24121 atccacacca ttttgtaaag cttcattcgc gcgatgccat ttatcgatga tagccggttc
    24181 gcctctttgc aaaaaattcc cgctcattac agcaatgacg acctctgctc ctgttatttt
    24241 tcgtgccatt tccacatgat agcgatgtcc attgtgaaaa ggattgtact ctacgataat
    24301 cccgcagctt ttcatgcgca tcctccttca tagttatcga taaaaaagaa atagagacaa
    24361 gtaaaaaaag gcaaaaatcg gaaaaaatac ccgaactata taaactattc tcgcaaacac
    24421 aatacttctg cgacgaaaag ctgcactgca agagcaatgc ctatatcgtt cggatatata
    24481 atttatgttg aagatttatt cttttcttgt taactcgagc aggcaaaacc gctagtcttt
    24541 gtatgctaca aagaaccagc gctttgattt ctctgatgct gcttcgtctg taaaatcaga
    24601 aaatgcttcg actttcgaaa agccgctgtt ttccagcatt cttaaataac tttccaatgg
    24661 ataggtacgc tcttgatgta gttcatcttc acgaataaat cgaccagacc cttcttgttc
    24721 ttcaacgaaa aaggtaagaa aatgttcgat gctgtgtttc tcgcttcctg gataactatc
    24781 ccacaaaaaa gcaaaattat ccccttgata atgatagcta tattctggaa aaacctcatc
    24841 tacttgatag gtggagtgta cgtcaaataa aaatcggcca ttttcttcta acgcttgata
    24901 gacttcatca aacacttgct gtacctcttg tctatttttc atatagcaca gcgaatcaga
    24961 aaaacaggta attgcctgat attgtccgat ttctgataaa tcgagcatat tgccttccac
    25021 aaattggatc gatgcgtctt cttcatatgc tcgctggctg gcaatcatca acatctcttc
    25081 tgaaaggtct aaccctgtca ctttatatcc atcttttgca aaggcaaccg ctaatgctcc
    25141 agtaccgcat gccagttcca aaatattttt tgtgtcttct tgtaaatgac gtttcgaaaa
    25201 agctaaccat tgctgataaa gtgtttcgtc catcacttca tcgtaaatga aagcaaatgt
    25261 ttcataagcc atatgttaat ccaaccattc actaagatcg actagcggag catctgacca
    25321 tagtttttcc agattataga aatttcgttc tggcgcatgg aaaacatgta cgatcacatc
    25381 tccaagatcg atcaataccc attttccgcc ttcttttcct tcaatacgtt ttacttcata
    25441 tttgttttct tcttctttat caatgatttc ttctgtaatt gcgttgattt gacgttcgct
    25501 atttgctgaa cagatcatga aataatctgc caacaaggaa acatttcgaa cgtctaaagc
    25561 gataatgtct tctgcccgtt ttgaatctgc tgcttcaatc gcaattttta attgttcttt
    25621 actatctatg atgatttcct cctaatatga gcagcttatt tttttgctac ccagtaatta
    25681 tatgtttcga ttgtttttgg ataaatctgt tgttcttgcg caagcaaatg ggccaatgta
    25741 tgttttgttt caaatgctac agcttcgtct agatcagccc atgcaatggc tcgtgcatct
    25801 tgtaccccag gaaaatctcg acctggttca atatagtctg ctacataaat gattttgtca
    25861 aggagactca tcttagcagc cccagtcgta tgcacccgga ttgcatgaag aatctctgca
    25921 tcggtgattc ctaattcccg ctctacaaac gaagcgccaa caagaccatg ccagattgca
    25981 ttattataat tcaataactc cggatcaaaa ccgtctctta cgattaccat tttgaactcc
    26041 tcatctggtc gttcttttgc ataatcatgt gtcaatgcag caatactagc tttttcagga
    26101 gaagcaccgt attttttggc aagagccacg gctgtttctt ctactccaag cacatgcttg
    26161 aagcgttgtt cgctcattct catctgtatt ttttgcatca ggttttctct agaataagca
    26221 gtatattcat tactatagtc catattcata caacccttca ttttgaatat aatcaattac
    26281 tttatctgga acaaggtagc ggatagaaca gccttctttg atcttttgac gtattttcgt
    26341 ggaactgatg tcgatctcag gtacatctac ccaaattaca ggatatggag tatccgttgt
    26401 gtatcctggt cgacgtatac ccacaaagtt gaccatagaa gtcagctcat cgattttata
    26461 ccattttggc aaatattcta ccatatcccc accgataata aagtaataat ctgtatccgg
    26521 attgttttgc gtcaattcct tcatagtatc ataggtgtaa cttttcccac cacgagctaa
    26581 ttcaatcgtt tcaatctgca aaaaaggatt gtcttccacc gctaattcca acatgttgag
    26641 tcgatgtttt gcatcaatcg tctgtttctc atcaacatga ggtggctgat aagaaggcat
    26701 caaaaatacg cggtcaagac ctaaattccg gccagcttgt tcagccatca ctaaatgtgc
    26761 aaggtgaacg ggattgaatg ttccgcccaa gatccctact tgctttttct tctctaagaa
    26821 ttgaggcatt tcttcaggaa ataattgtga acgaacaaat gtcttagctt gcgtattcat
    26881 catggtcact ccttatattg cttttacttc ttttgatagc ctttgatact tttcttttgt
    26941 ggaaggtttg tataatacaa taacacgtcc aatgatttgg acgatttcgc aatctatttc
    27001 tttttctaat acttgagctg cttcttctgc aatctcatct gtattttgaa gtaacgatac
    27061 tttgatcagt tctctttttt ctaaagcttc ttcaatttga acgatcattg ctgaattgat
    27121 cccacctttt ccgatttgaa aaatcggctg aagatgatgc gctttgctac gtaaaaaacg
    27181 cttttgtttt cctcttaaac tcataatttt ccttcttcct taaatcaatg ctttgcgttt
    27241 caatacatct acaccctttg gcgcccagcc cgcaattact actggcgctg ttacagtgat
    27301 ccagcctaga ccggcaaaaa cgatgtctgt tttttctttc acagaaaact caaaacgaac
    27361 aagctccgga aatgcctcga cttcatcagg acgaggaggc tgtaataatc cacctacatg
    27421 tttttgataa aattcgtctg ctttttccag tttcgttcga tgaatattta catcatttga
    27481 cacataagca ataaatgaag cacgattgcc gctgataaaa tcaaatcttg caagtccgcc
    27541 caagaaaagt gtttgccctt cattcagctg ataaacttta ggtttgattt cttttaacgg
    27601 tgcaatgatc cgcaaatctt ttttacctaa gtagtgcgcc atttgatggc gatggataat
    27661 tcccggtgta tcaatcaaaa aatgcccgtc atctaaagga atctcgattt tatccaaggt
    27721 cgttcctgga aactgcgaag ttgtgattac atcttgtact cccgctgtat ttttgatgat
    27781 ttgattgata agcgtcgatt ttccgacatt tgttactccg acgatataga catcccgtcc
    27841 atcgcggtat tcttcgattt tttctaatag ttccgtcatc tcatgagatt tcttagcact
    27901 agttaataat acatctactg gacgaattcc tgcttcgtaa gcacgttcct tcatccattg
    27961 tgttaattta gtttttttca atgatttagg taatatatcc actttgttcc caactaaaag
    28021 tactggattg tcaccgacaa aacggtgtag tcctgggatt agtgaaccat tgaagtcaaa
    28081 aatatccacc acattgacga tcaatgcatc tttttgccct aattcattca gtaagcgcaa
    28141 aaagtcgtca tccgtcaatg agacatcttg ggtctcatta taatggcgta atctgaaaca
    28201 acgctgacaa tagacttccc cggaagctaa acctttttcc aaagccgttt gcggcgtgta
    28261 tcctaattca ccgggtttgt ttgtttgtat aacggcacca cagccgatac attgtaattc
    28321 ttctgtcatt cgattccacc tcgccagccc atatcagggt gttttgctaa tagataggcc
    28381 ataattcttt tttcccaaaa acgattaaat tgtgtcttcc aactatctgt tgcgataatg
    28441 ggttttacaa ggatgctacg tatccctgca cgattggctc cacgtatatc agtcataatc
    28501 tgatcgccta ccattactat ctcatcatct gctaaatcca attgtttctt tgctatgttg
    28561 atccctcttg ctaaaggttt cattgctcgt gcaacataca aaagatcaaa tttttcaatc
    28621 gctcgcgcga cacgttttga attattgttt gaaacaacaa caacagggat tcctgcattt
    28681 ttcatttcta aaatccaagt aagcaactct tctgttccat ctggattatt ccatgcaatc
    28741 aacgtattgt ctaaatcggt caatactgct ttgatgccta gattctttaa ttgggcaggt
    28801 gtaatctgat agatggcttc taccatccat gttggtttgt aatttgaaaa catgctgtct
    28861 cctcatctgc aaaaaatgaa ggagcacata aagtactcct caaccccgta ttatactgca
    28921 tatcagcaaa aaaaactacc tctatactcg ttcgtctttc agaaaaagca tttctttaca
    28981 aaatgaccaa aaataaagat tgatcacaga aaaatttaga aacaaaaaac aactaatatt
    29041 ggcggaacct cttgtatcgt ttttccagta atttatgctg atctaatcga acaagttccg
    29101 tcaatctttc aatcaacgct tttttcataa tgtgtgcgac tttatatcgt ggcaactgct
    29161 cgccgttgaa cgtttcagga ataactcgat caacgattcc taactcgcgt agttctggcg
    29221 cagtaatttt catcaactca gctgcttctg cggcgcgact accgtctttc cacaaaatcg
    29281 acgcaaatcc ttctggagaa agcacagcat aaatcgtttc ttccagcatc cagacttcat
    29341 ccgctaaacc tagagcaagg gcaccgccac ttccaccttc accaatgatg atggcgatga
    29401 tcggtacctt taaatcagac atttcgagca gatttctggc aatagcctct ccttcgccgc
    29461 gctcttctgc tcctacaccg caatatgcac ctgctgtatt gatcaaggta atcaccggtc
    29521 tattgaactt ttccgcttgt ttcatcagtc gtaaagcttt tcgatagcct tcaggatggg
    29581 gagaaccaaa atttctgcgg atattttcct gcagatcccg tcctttttga ataccgatca
    29641 ctgttaccgg tttgccatct aatcgagcga ttccaccaac aatcgcttcg tcatctgcaa
    29701 ataaacgatc accatggcat tcctcgaaag aatcgaagat ctcttcaaaa aaatccaagc
    29761 ttgtccatcg ttctttagct cttgctaact gaacgacatc atgtgctgtc ttatccacga
    29821 tctatccatc ctttctgtgt atgcaattca agaagcgtat ggattttctg tttcaattcc
    29881 atgcggggaa caatctgatc gacaaaacca tgagataata agaattcagc cttttggaaa
    29941 tcttctggaa gttcctgctt gatcgtctgt tcgatgacgc gtcttccagc aaaaccgatc
    30001 aagctttggg gttctgctag aataatatcg ccttccattg caaaactggc agttactcct
    30061 ccggtcgtcg ggtccgttaa aacagttaga taaaaaagac cttcattgct atgccgtttg
    30121 acagcagcag agatttttgc catctgcatt agagaaaaga ttccttcttg catccgtgcg
    30181 ccacctgaag ctgtgaacaa gacgactgga agactttcct ttgttgctcg ttcgaataat
    30241 ctggtgatct tttctccgac aatcgttccc atacttccca tgataaaatt aggatccatc
    30301 actccaataa tgaagggaat cccctgaatg gttgctttac cagtgaggac tgcttcatga
    30361 agtcctgttt tatcttgcat ttttttaatt ttttccgtat attcgggaaa tgctagcgga
    30421 tctttggtta caagatccgt atcccattct tcaaaacttt tttcatcaat aatcaaagct
    30481 agacgctgcc atgcaccgat tcgaaaagcg tatccgcaat gagggcatac tttttcttca
    30541 ccgatgtctt tcgtataaag gatatgtttg caatttggac actttgccca catgttatca
    30601 ggaacagatg gcgagttagc aggtttgctc tctctattag gattgatccg aatatatttc
    30661 tttttcttaa acagagccat ctatgcgcct cctatctccg tttctggtgt ccaattcggt
    30721 aaaaattctt cttgtaaaaa tgctgtgctg taatcacctg ctatgactgc aggatgacta
    30781 atcaaatcca tctgaaattc tgcgttcgtg atgattcctt ctgtgataaa ttcacttaag
    30841 gctcgctgca tcttcattaa tgcttcaaaa cgcgtatttc catggacgat tatttttgca
    30901 atcattgaat cataatatgg cgggatcgta tatcccgggt aaactgcact gtctactcgc
    30961 agtcccatcc cacctgctgg aagcagtaag ttttggatct tccctggaga aggagcaaaa
    31021 tggaaagcag gattttctgc attaatccgg cattcgattg cgtgtccttg gaatactact
    31081 tcttcttgac acacattcaa aggctcaccg gctgctatct ccacctgttt ttttactaaa
    31141 tcgattcctg tgaccatttc tgttactgga tgttccactt ggattcgagt attcatttcc
    31201 atgaaataaa aatcgccttc ttcatccatc agaaactcga tcgttccggc attttcataa
    31261 ttgactgctt tagctgctcg aacagcagcg tctcctagtg cttctctttt tgtttgtgag
    31321 atcactacag aaggagattc ttccagtact ttttgattgt tgcgttgtaa agaacaatct
    31381 cgctcgccta aatgaatgac atgaccaaat cgatcaccta agatctgaac ttctatatgg
    31441 cgagcaggat aaatgatttt ttccaaatac atatcatcat ttccaaatgc cgctgctgct
    31501 tcttgctgag ctgaagaaaa atgctgtggg agctcttctt ttgattgaac tttccgaatg
    31561 cctttcccgc caccacctgc agctgctttc agcatcactg gataaccaat tctgtctgct
    31621 atttccaatg cttcttctac tgtagataat acaccagtac ttcctggaat gactgggaca
    31681 tttgcttctt gcatcaattg acgcgcattg atcttatttc ccattgcatc gatcgttgca
    31741 cttttaggac caataaatgt gatattgcac tcttcacaca tggaggcaaa tcggctattt
    31801 tcagataaaa aaccaaatcc tggatgaatt gcttcggctt ttgtcacgat tgcagcgctc
    31861 agtacttcct gaacattcag atatgaatca acggcttttg ccgggccaat gcagattgct
    31921 tcatctgcta actgtgtatg aagtgcttcg gcatctgctt ctgaatatat cgctacggtt
    31981 tggatcccta gttcgcggca tgcacgaatg atacgtacag cgatttcacc gcggttagct
    32041 atcaatactt tagaaaacat atttcaccta tccaatcata aaggttaatt ccgcttcggc
    32101 tactttttta ccgtctactt tagcgattcc tttgcctatt ccggctgaag ctttcacttt
    32161 caatatctca acttcaaggt ataaggtatc tcccggtgta actttcttac ggaattttgc
    32221 tttgtccaat ccgccgaaat aagccgtctt tcccttgaat tgttcaagag aaagtaatgc
    32281 aactgctcct gcttgagcca ttgcttcaac aatcaatacc cctggcataa caggttcttc
    32341 tggaaaatgt ccttgaaaaa agggctcatt gatcgttaca tttttcttag caacgatccg
    32401 ttctccttca accatttctt ccactcgatc aatcaaaagc attggataac gatgtggaat
    32461 gatttctttt atttcttgta tgttcattgt tttccctctt tcctgctttg cttatttttg
    32521 ctgaatccta aagagtggct gtccatattc gacaactgac tcgttttcta caaggatttc
    32581 tgtgatcact ccgtcggcct cactagttat ctcattcatc agtttcatcg cttcaataat
    32641 gcagataact tctcctttgg caacttgatc acctactttt ttgaaagctg gtttgtcggg
    32701 cgctggttgc agataaacga ttcccacgat tggcgaaaca acctcgattc catcaaatac
    32761 tgccgattct ttttctttca ttatttctgg agcagttgtt gcttgttcag gtatgacatt
    32821 gactggctcc gaaactggca acgtttcgtt tgtttgaacc atattcatgc ctcgacttgt
    32881 tttattttta ttcatataca attcaaattg accttcacgc aaatcgaatt ccgttagcga
    32941 ggattgatca aattgactga ctaattctct gatttcattg atatccaaaa ttattcctcc
    33001 cagcgtttca tgcacagaac cgcattatgt ccgccaaacc ctaatgaatt actcattgca
    33061 taagtaaaac ttgcaggttt gctttcgttt ttgacaactg tcaagtcaat ctcaggatct
    33121 tgtttttcta cattgatcgt aggtgggata aattgatgtt ctaatgccag caaagttgcc
    33181 aaggcttcga tcccgccggc tgctcccaat aaatgtccag tcatcgattt cgtgctgctg
    33241 acgtaagtat ctctgaaatt ttcacctaat gcgatttgga ttgcttttgc ttctgcctgg
    33301 tcattggctg gtgtacttgt tccgtgagca ttgatatatc cgacttgttc cggctgtaca
    33361 ccagcttctt ccatcgcaag cttcattgct ttagatgcac cagaaccatc tggagtagga
    33421 gctgtcatat ggtaagcgtc acagtttgca ccgtatccaa cgatttctcc atagattttg
    33481 gcaccgcgag cttgtgcatg ttctaaagat tcaagaacta gaacgcctgc tccttcaccc
    33541 atcacaaaac cattccgatt ttcgtcaaac ggaatcgaac cacgattagg atcagttgat
    33601 tctgagagtg ctgttaaagc tgcaaatcca gcaatcccca tctcacaaat cgttgcttct
    33661 gttcctccag caagaatgac atcagaatag ccatgtttga tgttacggaa tgcttcccca
    33721 attgaattcg ttccgctagc acaagctgtt acgatagctg tacaaatacc ttttgcacct
    33781 acacgcaaag caatatttcc agctgccatg ttggcaatcg ccattggtac gaacattgga
    33841 gaaactcgtt ttgcaccttt ttcatgtaga cgaataactt ggttttcgat tgttggaaga
    33901 ccaccgatcc cagatccgat gatgacgcca aaccggtctt gattcatttt ttctttatct
    33961 aaaccgctca tctccattgc ttctaaagca gcgtagattc catagatcga aaacatatcc
    34021 attcgtttgc tatctttttt aataaaatat ttatcgtaag ggaaatcttt gacttcaccc
    34081 gctaaggtaa tccctgtttc tgaagcatca aatttagtga tcggtgcgat gccattcgtc
    34141 ccctctttta agctattcaa aaagctgtct gcgtcatttc caataggtga agtgactcca
    34201 tagccagtaa ttaccactcg attcatttgt ttgctctcct tttcttatcc gtgcatgacc
    34261 aatccgccat cgacattgat gacttgtccg gtgatatatg gattttgtgc taagaaaact
    34321 gctgtttgtg caatatcttc tacttgtccg aaacgctgca tcggaatttg cttttccgct
    34381 tgttccttga ctttgtctgc taaaacttcc gtcatatcag ttgtgatgaa tcctggcgca
    34441 atggcattac atgtaatgcc tctagttgca gcttctcgtg ccacagattt tgttaatcct
    34501 actacgccag ctttactagc tgcataattt gcttgaccaa tatttccaat caacccagat
    34561 acactagaga gattaatgat ggccccttct cgctgcttca tcattttttt caatacgtgc
    34621 tgcgtcatat tgaaggttcc aatcaaattg atatccagac attttttgaa atcttctgca
    34681 tccattcgca tcacaagttt gtcatttgtg attccggcat tgtttactaa cacatggatc
    34741 gatccaagct tttcttctgc ttctttgatc atttgtcccg ctttctcata atcagagatg
    34801 tcaccggaaa ctcctacgca ttttacaccg aatgcttcga tttcttctat cttttctttt
    34861 ggaatctctc cgcgaccatt caaaatgata tttgctccag cttttgcaaa agctaaggcc
    34921 atcgctttgc cgattcctct tgtactacct gtgataaata cattttttcc ttttacatcc
    34981 ataacgttcc tccttatagt attgctattg tttcatcaaa tgtctgctta ttctcaacac
    35041 gcagaactgg tattgtttta tcgatttttt tcataaatcc gcttaatact tttccggggc
    35101 cgacttcgat gacttgttcg atgccgattg tttttaactt atggatactc tcatagaaac
    35161 gaacaggttg catgacttgc tgttcaagta gtcccgcgat tgtttctttc ttcattattt
    35221 ccgttgttgt gttgcttatg ataggaaaag aaggttcaga gaattgaatc tgacttaggt
    35281 ccttcgccag tttttttgct gccggttcta aaatagctgt atgaaaaggc ccgctgacat
    35341 ttagagggat cattcttttg aacccttttt cttttaatag taaaacagct tcgtctactg
    35401 ctttttcttc gccaccaatc acgatctgct gaggtgtatt ataatttgca ggagatacga
    35461 tgccgtactt gctagcttca tgacagcttt cctcgatcgt ttcaatcggc gcattcatca
    35521 ctgcaaccat tttcccgctt ccagctgggg cagcttctgt catataagcg cctctttttg
    35581 ctactaacgc aactgcttca gtgaaggata gcgcattact agctactaat gccgaatatt
    35641 ctcctaaact cagtcctaaa gctgcatctg ggatgattcc atgctccttc aataagcgat
    35701 aatacgcgat gctgactgtt agaatagctg gctgtgtata ttgcgtctga tccaaacgtt
    35761 cattttctgt aaagcaaagt tcagccatat cgtagccgag aatctcactt gcttcatcaa
    35821 atgtctgctt tacaacggct tcttcatata aatcttttcc cataccttga tattgtgcac
    35881 cttggccact aaataagaat gctgttttca tgtttttctc caatatatcc agaatatatg
    35941 tttgattctt cctattcaaa aaggccgaga cattcctatt tcaggaaatg tcccagcccc
    36001 caacctaatt ttaatgatta tgcagtttgt ttttctacgt aagtcactaa atcttgaacc
    36061 gttttgattc cgtcttctgt ttcgattttc acgtcaaatt catcttcaat ttcattgatg
    36121 atttggaata aatccaagct gtcagcttct aagtcttctt ggatgtcagt agtcaatttg
    36181 atttcttcag tttcttttcc taattcttct gcgatgattt cttgaatttt ttcgaatacc
    36241 ataataatat attcctccga tattgtttgc tttttatttt tataatttaa cagtctacaa
    36301 ctccatgaga atacttcccc atgttaaacc tccgccatag cctgtaaata ttactttctg
    36361 ctgttttcct aaggtgatct ttccactaga aactgcttca tccaataaga tagggatgct
    36421 tgcagcagat gtattcccat atttatccat attggtcagg aacttttctt gcggcatctt
    36481 tacttttcgg gcaattttct caataattct gaggtttgcc tgatgcaaaa gcagataatc
    36541 aactggtttg tctttcatga cttcttggat attgtttgca acgtctcgta cggcaaaatc
    36601 aaaaatatct ctgccagtca tttgcaaata atacgaacct tctgaatctt ctgaatagaa
    36661 cggattttta ttttgctggt agccagcggt caatgagcta cttctggtac cgtcagctgc
    36721 taatttttct ttcagcaatt ttttctgtgg attcgcttct aagagaatcc cacctgctcc
    36781 atcgccaaac aacacagcag tcgtacgatc agaccaatcg attagcttag atagtgtttc
    36841 accaccaatc accagtccct tagttgagcc gcagcggatc attttttcag ccatgcttaa
    36901 cgcataaaca aatcctgagc acgcagcact gatatcaaaa gcgatagcat gagttgctcc
    36961 caatttccct tgtacttgtg ctgctacaga tggtgtcgtg taatcgggcg acattgttgc
    37021 tactaaaata aaatccaaat ctttagggtt tagatttttc tgttttatca atttttccgc
    37081 cactaaaatg cataaatcag aagtctcctg atttgttaca catcttcgtt cacgaatacc
    37141 cgtccttgac gaaatccatt catcagaggt atccatcatc ttggaaagat cattattagt
    37201 aataatcttt tcaggaagga cgctggctgt tgcagtaatc attccaaatt gttccattaa
    37261 atatcctcac ttatagtctt gcaagaagtc gtgcaagttt ttcagtgcat ccagcaaggc
    37321 atgctgttcc tccgtagcca ttccgtctaa gatgttcttg accatttcac gatgaaaatg
    37381 ctgatggacc cgaaatagta actttccttt tttcgttagt cccaacttta caacgcggcg
    37441 gtcatcttca ctgcggatac gttcgacata gccttttttt actaacttgt taatagcagt
    37501 ggtcaaggtc ccaacagtaa ttgatagttc tttggctact tctgaagttg tttttttctt
    37561 gtacatcccg attgcctcga tcgtgtgcat ctctgtgatt gacagatctt tgaattgaga
    37621 ttttttcagc tcagactctt cgattgtcaa aatatcattg aagacactaa caagataatc
    37681 atttactgtt tttaaatctg gttccatgtt ccaccgtcca ctaattagtt tgattatcaa
    37741 atcttttgat gttcaaacta tatcttaact tttttcaaaa tgcaacctta aaagatcatt
    37801 tttttactat atgagctttt tttaagattt tactcattta aaacaactga taaatcagca
    37861 tttataattt cttttattag aaaaatcatc tatctcacat attttgatta tcaaagtatt
    37921 ttctgtgaac agaactatag aattccctaa aacttgtcca ttatttcaaa atttgttata
    37981 gtctttttat tcaaagcgta aaaggagatc ctatgttaaa agaaaaaatg aaaactctcc
    38041 ccatgctgcc gggtgtctat cttatgaaag accgagatgg taaggtcatc tatgttggta
    38101 aagcaaaacg gctcaaaaat agagtaagca gctattttca tcagaataaa cagcattcaa
    38161 aaaaagtatt acgtatgatt catcatataa cagattttga tttcgtcgta gtagacacgg
    38221 aattagatgc tttattgctc gagtgtcaat tgatccaaca ttaccgtcct ttttataacc
    38281 gacaaatgaa ttatttcagt aattataatt atgtacatat taccaataag ggatttgtat
    38341 taacagatac tcctacggct cgaacatacg ggccttttcg tctctataaa aaaatgccgt
    38401 ctattttgcg tataatggaa gaaacttatc aaatgccttg gttgtctgaa attagtttgt
    38461 tagctttgcg agtccagctt cctgacctac aggaaatgac ttttgaacag aaaaaaaagg
    38521 aactccaagg gctgtttcaa ggccgaaata aaaagctact gacttacttg aaaaaaagac
    38581 aacaacattt catctatcag ttgaatttcg aaaaagccgg tatgcttcaa aaagatatcg
    38641 aattagttac ttattttatt agacggatcc aggaacaaaa gcagttttta agaacaccat
    38701 cgctcacctt cagcatgcca ttagcagcag atgagagtca gaaaaagcac tacctcgttt
    38761 gttatggtca acttgcagaa acaatgatta cctctggtga cgtttctcct gacttctatt
    38821 atgaaaagaa agaagctcat ttatctttga aacgtcaatt gtcaaaagaa gaaatcgatc
    38881 ctgtacaaat cttgatcagt taccgcaaaa aattagaaaa agaacagttt gaaattgaac
    38941 tgttaaacaa aaaagaagct gaaaagcaac taaattagtt gcttctcggc ttcttttagg
    39001 catcttcaac ttcaaatgtc aattatccta aaatttattg gattaagtca tagatttcca
    39061 tcgctacgat atcgatatta tcaaattcgt attgctgatg agtatctgtt tcagttaatt
    39121 caaatgtatc ggtcgcttta tcataagtta ctgtacactt ctctacgcct tctttttcaa
    39181 aacggcgaac ttgcagttca ttatctgctg actcgaccat agcctccagt cgttttatga
    39241 ttgcgactaa ttgtgaatgt gtcatcggag gtcctccttt tcttatttct gttatattgt
    39301 atcaaaagca tagcctactt gcattgattt tctctaaaaa aactcgtttt ttatgatttt
    39361 ttttctggta tttttccttc aggccaccaa agtttgatca aagcttgggt tccgtcattc
    39421 tcaaaacctt tatctgccaa ctcttcatat agtttcaatg cttgggtagt tgctggcaat
    39481 acaagatcca ttttttctgc ttcttctaat gcaatcttta aatctttgat aaaatgtttg
    39541 acaaaaaaac caggtgtgta atcttctttt aaaatacgag gagaataatt gcttaaagac
    39601 cagttagctg cacttccacc tgaaagcgtc tcaatcactt tctttaaatc aagtccgttt
    39661 ttttgtgcat agacaagcat ttccgtcatt cctgtcatcg tacctgcaat catgatctga
    39721 ttagccattt ttgtatgctg acctttccca gcagaaccat gcaatgtaaa tgtcgtacca
    39781 aattctttga ataaaggcag tacttgatca taaacggctt cttctccacc gaccatgatc
    39841 gtcagtgtac cattctttgc tcctaagtca ccaccggata ccggtgcatc taacgcatct
    39901 gcgccttttt cttttgctgt ttttgcaatt ttttctgcca ggcttggtgt acttgtagtc
    39961 aaatcaacta aaatatgtcc tgagatatct gcagaaaaaa tccccgactg tccatagtag
    40021 atttcttcta catctttggg gtaacctacc attgtaaaga gaatattact ttgttctgct
    40081 accgcttttg gtgtatctgc ccagatagct ccttctgtta ctaaaggatc agcttttgct
    40141 tttgtccgat tatagacagc tacttcgtgt cctgcttcta gtagatggcg tgcgacagca
    40201 cttcccatga cgcctgttcc gataaaacca agtttcattt tttcgacctc ctaaaaatca
    40261 aaaatccttg cttctatgct agtatacgct agaaacaagg attttttcat aaaaaatgtt
    40321 tgaattttat cttttaaatg aatttaattt tattttgatt cgttcaatcg agtcttcttc
    40381 ttcttttctt cgcatctctt cttcatgata aacaaccatg tcttgataaa attcgatcat
    40441 agcttcgccg aaatgtgtag atgaaatatc ataaagttta gcttctaaaa cttttggatc
    40501 tttaggaact tcactggaaa tataatcaat aagtgctggt gcaaagtctt cgtcggtttc
    40561 aaaagttttc cctaatgaag gatgatcgaa caatcggttc aaataagcat ttccttccac
    40621 gacacaaggt gttccggctg ccatcgcttc tgtataagta agcccttgtg tttctgaagt
    40681 agaagcactg acaaaataat ctgccgcttt ataataaagt gctacatcat tgttgtccac
    40741 ttctcctgtg aactgcacaa attcttctaa ctgcagttct gagatcaatt cctctaactc
    40801 ttctacataa ggtccttttc ctacgataac taatctggcg ttaggataag cggagatgac
    40861 ctgaggaaac ccattaatca aggcttggat atttttctca taagaaatcc tgcttaaaga
    40921 aagaatcatc aaatggtttt cctgaagacc tagtgactcc cttaatttgc tgatatcctg
    40981 ctgagtgata tcagaacgtt tgaatttttc aatgtcgata ccagtaggaa tcacgcgaag
    41041 cggtgctatt acaccatagc tgcgtaatgt atcaataaca cgttcacttg gacaaactac
    41101 acctgtcgta tgatttgcaa ataatctaga caagtatttt acatgggatt gcctgatcac
    41161 ttttccttta ccgatataat gaaggtagtc ttcatacatc gtatggtaag tatggatcag
    41221 aggtattttc aacttcttag ctaccatctt cccaagtatc cctgctccga attctgtatg
    41281 ggtatgaata agatctagtt ctagttcttt ggcaaccaaa taagcatacc acatgcctct
    41341 aacaacaact cttcgatcct tgaaagaaat aaatggtaca cttggcattc gaatcacatc
    41401 tttttccaac ttatccgcat taggatcggt cgttgtaaaa atatagactt catgcccatg
    41461 tctttctaat tcttgtttta atgttttgat cgatgtagca actccgctga cttgcggaaa
    41521 gtaggtatcg gtaaaaaagc cgattttcat gtttttcgcc tccaaactag tccttgacct
    41581 gatttacttt ttttaatttg ctagagactt tttcattcag tacactttcg tatacatttt
    41641 taagttcttc accgatttta ttgatacttc gctcttttgc tgtttgataa ccggcttgtg
    41701 tcgtactcgg tagttcttga ttggtaatct gttggatcag tcggataaat tcttcgtttg
    41761 tcttccccat atagcagttc ttgctatctt ctaaccagcc attatacact ggaatatctc
    41821 gaacaagtac gttttgtttg cttgctaaag cttctaaaac aacgatccct tctgtctctt
    41881 cataagaagg gaaaaagaat agatctgcac ctgaatacgc accttctatg atctctccac
    41941 gaatgtaacc aggaaacagg acattttcag gatgatcttc ttttacaatt ttccggatgt
    42001 tccgaggaat cgagtacatg ggaacatgac caaaccaaat aaatgtgtat tcgggcatct
    42061 tcttagcaat ttctacgaaa tcaatgattc ctttacgttc gaaaaacaaa ccgacacaaa
    42121 tgattacttt ttgatccgga gacagtttga aatattctct gaacttttgt tctttcattg
    42181 gatcagggtg atatttctct aagtcgatcc cattggaaat agcttgaatc ggcacacgga
    42241 taccatagct ttccaacaac tgttttgaat aaggtgttgg cgtgatcaga tagtccgctt
    42301 tttggtacaa tcctaccaga tattttttta cgataggaga aagctggttc gatccgataa
    42361 aggaatttcg gaaatcttcc tctgtagaat gcgcatgata gacaactttt tttccttctc
    42421 ttctggcttt attgaccata ttatgactat tgattccgta tgtattgatg tgcaggatgt
    42481 cataatcttc tttttcatct agtgtataag agataccgac ttccgtcaga gcacgttttt
    42541 gatgatcaag cgcacgcccg attccagatt ttgcaagcat cttttcactt tcaaaatata
    42601 ataatacctt caccttacgt cccccttcac ttatatagta taacatagcc tacaaactgt
    42661 cactcaaact taagccctat ttttgtctat tcttactgac aaaaacgttt tcttaaaaaa
    42721 gaacaaaaaa actggcgtag ctcttttaca agccacacca gcttttgata cgttgtttat
    42781 tttacatatt catgaacaag ttcaacgact tcttccatcg tatcgcattc tttcaatgca
    42841 cgatcagcaa gttcagccat tttcgctgtg tccaagcgtt tcattaaact acgcgtttta
    42901 agaatagatg tcgcactcat tgagaactca tctagaccca tacctactag caatggaaca
    42961 gctgtttgat ctccagccat ttctccacac atacctgccc attttccttc agcgtgtgct
    43021 gcatcaatta catttttgat caaacgtaaa attgatgggt tatatggttg gtacaagtaa
    43081 gaaacgcgtt cgttcatacg gtctgctgcc attgtgtatt gaatcaaatc gttcgtacct
    43141 acagagaaga aatctacttc ttttgcaaac ttgtctgcta agactgctgc tgctggaatc
    43201 tcgatcatga tgccgacttg gatcgtatca gatacttcct tgccttcact tatcaatttt
    43261 tgtttttctt cttcaaagat cgcttttgct gcgcggaatt ctttgagtgt agctaccata
    43321 gggaacatga tacgtaaatt accatgaaca gatgcacgaa gcaatgcacg catttgtgta
    43381 cggaacattt cgtcgccttg ttcagataaa ctgatacgca atgcacgata tcctaagaat
    43441 ggattcattt catgaggtaa ttgcagatat ggtagttctt tatctccacc gatgtccatt
    43501 gtacgaacaa ctacaggttt tccttccata ccttctaata cagctttgta agcttcatat
    43561 tggtcatctt ctgttgggaa gtctggagaa tccatataca ggaattcagt acggtacaga
    43621 ccaactgctt ctccaccatt attatggaca ccaactagat cttttggtgt tccgatgttt
    43681 gcagctaatt caaaatgctt gccgtcagct gtgacagttt ctgcattttt taatttttcc
    43741 cattctgctt tttgtgctgc gtaatctgca cctgcttttt caaattcagc tttttgttca
    43801 tctgtaggat cgatgattac atcgccttcg atcccgttga cagccaaaat atcgccttct
    43861 ttgactttag cagtaatttc ttttgtccca acgattgctg gaatttctaa agaacgtgcc
    43921 atgatagcag aatgtgaagt acgtccacca atgtctgtta caaacgcttt tacaaaattg
    43981 cgatctaatt gtgctgtatc acttggagtc aagtcatgtg caacaacgac cacttcttcg
    44041 ttgatcattg atggatttgg taaagtaacg cctaataagt gcgctaaaat acgtttagca
    44101 acgtcacgaa tatctgcagc acgctcttgc atataagcat tatcttccat tgcttcgaac
    44161 ataccgatat acatatccgt tacttctttt agcgctgatt cagcatttac gctgttgtct
    44221 ttaatatttt gcttgatttg acctaccatt tctggatctg aaagaaccat caaatgggca
    44281 tcaaatactt gcgcttctgc ttcacctaag ctttgcgctg ctttttcacg aatttgctgc
    44341 aattcttcag tagatttagc taatgcagca tccaaacgag cttcttcagc cgcagtatct
    44401 tctactgttg ccttactgaa tgttaaatcc ggttgaacta gcaggtaagc ttttgcaacg
    44461 gctacaccgt cactagcggc aatccctttt agcatttcaa ccattattca gataagcctt
    44521 ctttcttcat tgtttcaacg attgctgcca ttgcatcagc ttcgtcagca ccttctgcag
    44581 taatagtaac atcagaacct tgacctacac ctaaagacat aacgcccatg attgatttca
    44641 agtttactga tttaccttta tactctaagt ttacatcaga gttaaatttg cttgctgttt
    44701 gtactaatag tgtagctgga cgagcgtgga tcccagtttc tgctactacg tgaaattctt
    44761 tcttttccat attaatcggt ctcctttaag tgagtgttgt ttttatgtga gggttttctt
    44821 ttttagtaat tcagagaatc ctaacaaatg ccaccctttc atctgtaaag attaacattt
    44881 tttttcgtta gatacaacag ttttcattca atttcagata aaagtattca aattattccg
    44941 gattcttttt catccttttc ttcacatttt ataacaaacg tgtttatttc ctttttcttg
    45001 tcgctttctc ttctcctgac gtttatcatt ctttcctttg accctctttg ttttcatatg
    45061 aaacgaatta cttgcttccc tttttatttt tagtataata agagtcaaag gtcaggaatg
    45121 gtcaatagag atttcacctt ttctacctca taaatctctt aaaaaactag gggttattct
    45181 tttacctcat gaaaaacgag atgtaaaata tggatgtacc catttttgtg aaaggacgtg
    45241 aatgattcat gctttgtcaa aactgcggca agaatgaggc aacgattcac ttgtatgcca
    45301 ctgtcaatgg tcagcggaca caactcgatt actgtcagag ctgttatcaa aaaatcaaaa
    45361 atcaacaaaa tggaggtctg actaatatgg cccaaaatga tccatttgga tttggcagtt
    45421 tggacgatct tttccgttcc atgtctcgcc aaatgcaaca gcaaggaaat tatgagcaaa
    45481 caccaccaac acaatttggc ggaaacaaca acttcaatgg tggtcagcca cctcaaggca
    45541 atacagaagg tttattggga gaatacggaa tcaatatcac agaacaagca cgacaaggtg
    45601 atatcgatcc tgtgatcgga cgcgatgacg aaatcaaacg agtcattgaa attttaaatc
    45661 gccgaaccaa gaacaatcct gtcttgattg gagaaccagg tgttggtaaa acagcagttg
    45721 ttgaaggttt agcacaaaaa atcgtagatg gtgatgtacc gcaaaaatta atggacaaag
    45781 aagtcattcg tttagatgtc gtatctttag tccaaggtac tggtatacga ggacaatttg
    45841 aagaacgtat gcaaaaattg attgaagaga tccgtcaagc agaaaatgtg atcctattca
    45901 tagatgaagt tcacgaaata gtcggtgctg gttctgctgg tgatggaaat atggatgctg
    45961 gtaatatttt aaaaccagct ttagctcgag gagaattgca aatggttggt gctactacct
    46021 taaatgagta ccgcatcatc gaaaaagacg ctgctttaga acgtcgtatg caacctgtac
    46081 gggtagatga accaactgtc gaagaaacga tcagtatttt gaaaggtttg caaaaacgtt
    46141 atgaagacta tcatcatgta aaatatactg atgaggccat cgaagcagcc gcaactttat
    46201 ccaatcgtta cgtccaagat cgcttcttgc cggataaagc catcgatttg ctagatgaaa
    46261 caggttctaa gaaaaacttg acgatccaaa tcgttgatcc taaaacaatc gagaaaaaac
    46321 tgcaaaaagc agaagaacaa aaagttttag cttctcgaga agaagatttc gaaaaagcag
    46381 cttattatcg cgatcagatc aataaacttc aaaaaatgaa agaacgtcag ctcactgaag
    46441 aggaaacacc tgtgattacc gaaaaagata tggaaaaaat cgttgaacaa cggacaggta
    46501 ttccagtggg tgaattaaaa gaaaaagaac agacacaact gaaaaactta gcagatgact
    46561 tgaaagctca tgtcatcgga caagataacg ctgtagatcg agtagcgaaa gcgattcgcc
    46621 gaaaccgtgt tggattaaac aaacagaatc gtccaatcgg ctccttctta tttgttggac
    46681 caactggtgt aggtaaaaca gagcttgcga aacaacttgc ctacgaacta ttcggttcac
    46741 aagattcaat gattcgtttc gatatgtctg aatatatgga aaaacatagt gtctctaaat
    46801 tgattggttc tcctccaggt tatgtcggat acgaagaagc tggtcaatta acagaaaaag
    46861 tacggagaaa tccttacagt cttgtcttgt tagatgaagt agaaaaagct catccagatg
    46921 ttttgcatat gttcttgcaa atcttagatg atggtcgatt gacagatgca caaggaagaa
    46981 cggtcagctt taaagatacg atcatcatta tgacaagtaa tgccggaact ggtaaagtag
    47041 aagcaaacgt tggttttggt gcggcacgcg aaggtgttac tcgttctgta ttgaaccaat
    47101 taaacaacta ctttacacca gaatttctga accgttttga cgggatcatc gaattcagtg
    47161 cattatcaaa agaaaacttg atgacaatcg tcacactaat gctagacgat gtcaaccaaa
    47221 tgctggcagc acagcaactt cacatcgaag ttcctacgaa tgtcaaagaa aaattagttg
    47281 acttaggcta tgatccatct atgggtgctc gtcctcttcg acgcacgatc caagaacaaa
    47341 tcgaagatgg tatcgctgaa ttttatcttg atcacccttc tatccatgag ttgaaagcaa
    47401 aactggataa agatggaaaa atcatcgtta cttctaaacc agaacgtttg gctaaagaat
    47461 cagccgaaga aacggctgaa taaatccagt tttatagcgt gagacggtat ttctttgaga
    47521 aatgccgtct cattcttttt tcagaaaagt caaaatactg ttcattttat aaaaaagaaa
    47581 ttataataag agaaacaagc aattaaaaat acataaaaga ggtgagcgcc atgaaattgg
    47641 taaatgtaac aaacagccat tcccgtcttg tattaaacca gcttgaaaac actgatgccc
    47701 atctagtcaa ggtctacaca gccggaaata ccactattgt ctacactgaa gcccctgaac
    47761 ataatgaaat tctgctgatc aatgacaaac gtaaaatcca gccgaaagaa atcgaagatg
    47821 ctaaaaatta tttcttagat aaaatcaaag acgccgttta ccacgaggat gaaatcaaag
    47881 taatcgaatt ggcaggcctt gttgaaatct cgattccaaa acatgaatta ggcgctacat
    47941 tagccgtgta aacaaatttt gaacataata attaaagagc gtgggacaaa ag
//
LOCUS       DACBZK010000013        44952 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.013, whole genome shotgun sequence.
ACCESSION   DACBZK010000013 DACBZK010000000
VERSION     DACBZK010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.013"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            212..604
                     /locus_tag="IVD66_000806"
     CDS             212..604
                     /locus_tag="IVD66_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP6145050.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="IVD66_000807"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="IVD66_000807"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HAP6145051.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="IVD66_000808"
     CDS             3165..4775
                     /locus_tag="IVD66_000808"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HAP6145052.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="IVD66_000809"
     CDS             5067..5936
                     /locus_tag="IVD66_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HAP6145053.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="IVD66_000810"
     CDS             6101..7372
                     /locus_tag="IVD66_000810"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAP6145054.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /locus_tag="IVD66_000811"
     CDS             7369..8664
                     /locus_tag="IVD66_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HAP6145055.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="IVD66_000812"
     CDS             8763..9026
                     /locus_tag="IVD66_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HAP6145056.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="IVD66_000813"
     CDS             9471..9920
                     /locus_tag="IVD66_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP6145057.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="IVD66_000814"
     CDS             9977..11395
                     /locus_tag="IVD66_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6145058.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="IVD66_000815"
     CDS             11395..12255
                     /locus_tag="IVD66_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HAP6145059.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="IVD66_000816"
     CDS             12429..13202
                     /locus_tag="IVD66_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP6145060.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="IVD66_000817"
     CDS             13349..13714
                     /locus_tag="IVD66_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HAP6145061.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="IVD66_000818"
     CDS             complement(13862..15070)
                     /locus_tag="IVD66_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6145062.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="IVD66_000819"
     CDS             complement(15089..15367)
                     /locus_tag="IVD66_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145063.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15560..16216
                     /locus_tag="IVD66_000820"
     CDS             15560..16216
                     /locus_tag="IVD66_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP6145064.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16658..17455)
                     /locus_tag="IVD66_000821"
     CDS             complement(16658..17455)
                     /locus_tag="IVD66_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HAP6145065.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="IVD66_000822"
     CDS             complement(17452..18636)
                     /locus_tag="IVD66_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAP6145066.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="IVD66_000823"
     CDS             complement(18661..19908)
                     /locus_tag="IVD66_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virion core protein"
                     /protein_id="HAP6145067.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="IVD66_000824"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="IVD66_000824"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HAP6145068.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDMIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="IVD66_000825"
     CDS             21888..22202
                     /locus_tag="IVD66_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HAP6145069.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="IVD66_000826"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="IVD66_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HAP6145070.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="IVD66_000827"
     CDS             22887..23531
                     /locus_tag="IVD66_000827"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HAP6145071.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="IVD66_000828"
     CDS             23546..23875
                     /locus_tag="IVD66_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145072.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="IVD66_000829"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="IVD66_000829"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HAP6145073.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="IVD66_000830"
     CDS             24863..25687
                     /locus_tag="IVD66_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HAP6145074.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="IVD66_000831"
     CDS             25680..26027
                     /locus_tag="IVD66_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HAP6145075.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="IVD66_000832"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="IVD66_000832"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HAP6145076.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="IVD66_000833"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="IVD66_000833"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HAP6145077.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="IVD66_000834"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="IVD66_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HAP6145078.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="IVD66_000835"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="IVD66_000835"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HAP6145079.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31684..32451
                     /locus_tag="IVD66_000836"
     CDS             31684..32451
                     /locus_tag="IVD66_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6145080.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="IVD66_000837"
     CDS             32441..34483
                     /locus_tag="IVD66_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6145081.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="IVD66_000838"
     CDS             34764..34913
                     /locus_tag="IVD66_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HAP6145082.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="IVD66_000839"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="IVD66_000839"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HAP6145083.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="IVD66_000840"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="IVD66_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HAP6145084.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="IVD66_000841"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="IVD66_000841"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HAP6145085.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="IVD66_000842"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="IVD66_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HAP6145086.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="IVD66_000843"
     CDS             39330..40412
                     /locus_tag="IVD66_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HAP6145087.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="IVD66_000844"
     CDS             40412..41215
                     /locus_tag="IVD66_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAP6145088.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="IVD66_000845"
     CDS             41285..42025
                     /locus_tag="IVD66_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP6145089.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="IVD66_000846"
     CDS             42036..43040
                     /locus_tag="IVD66_000846"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HAP6145090.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44929)
                     /locus_tag="IVD66_000847"
     CDS             complement(43085..44929)
                     /locus_tag="IVD66_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145091.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT        14457 a         7838 c         9349 g        13308 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcgcgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagata tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg agcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 gtaaataaaa agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc
    44941 tttctaaaac tt
//
LOCUS       DACBZK010000014        43963 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.014, whole genome shotgun sequence.
ACCESSION   DACBZK010000014 DACBZK010000000
VERSION     DACBZK010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43963
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.014"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(1156..1554)
                     /locus_tag="IVD66_000848"
     CDS             complement(1156..1554)
                     /locus_tag="IVD66_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145092.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KVAVEKYFDSLEESAKEIFNGEKAGSYELDGIKFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
     gene            1770..2825
                     /locus_tag="IVD66_000849"
     CDS             1770..2825
                     /locus_tag="IVD66_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HAP6145093.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQNI
                     LSFSLANLARLEDQSDDVLTVNLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDESLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            2845..3198
                     /locus_tag="IVD66_000850"
     CDS             2845..3198
                     /locus_tag="IVD66_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145094.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQEHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(3380..3676)
                     /locus_tag="IVD66_000851"
     CDS             complement(3380..3676)
                     /locus_tag="IVD66_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145095.1"
                     /translation="MIEVKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAK
                     LKSDSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(3680..4498)
                     /locus_tag="IVD66_000852"
     CDS             complement(3680..4498)
                     /locus_tag="IVD66_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6145096.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAINENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWIVVNYEQLKEKYNLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            4724..4945
                     /locus_tag="IVD66_000853"
     CDS             4724..4945
                     /locus_tag="IVD66_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HAP6145097.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKELMKEHEENDQSISHEDMLKELGL"
     gene            4947..5213
                     /locus_tag="IVD66_000854"
     CDS             4947..5213
                     /locus_tag="IVD66_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP6145098.1"
                     /translation="MSYQVRYEREAQKTLKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            5326..5865
                     /locus_tag="IVD66_000855"
     CDS             5326..5865
                     /locus_tag="IVD66_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145099.1"
                     /translation="MYNISVNKLINFQKERFFMGWYGAYSSANKVIEEKKGYAKNGLE
                     IVDTKVTKTYGIILFKDAEGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFF
                     VGDQEKMVKRQLDRIKKESNKPKLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQ
                     DGSLTRFTRLSAGDVKEVS"
     gene            6023..6205
                     /locus_tag="IVD66_000856"
     CDS             6023..6205
                     /locus_tag="IVD66_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HAP6145100.1"
                     /translation="MINLFLLVTASTLFFTGISLIISYLIYKKAETYTSKATVLAVSS
                     FLTLLTFFVTLSFSFV"
     gene            6309..6593
                     /locus_tag="IVD66_000857"
     CDS             6309..6593
                     /locus_tag="IVD66_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145101.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGVVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKNSFIGKLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            6600..6845
                     /locus_tag="IVD66_000858"
     CDS             6600..6845
                     /locus_tag="IVD66_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145102.1"
                     /translation="MWTLEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTS
                     LECVWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
     gene            6867..7121
                     /locus_tag="IVD66_000859"
     CDS             6867..7121
                     /locus_tag="IVD66_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145103.1"
                     /translation="MNYTDEEQITLEYVFTNEKGEEIEKVLIISSKDLENALAYEPYE
                     STVTVNEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            7203..7388
                     /locus_tag="IVD66_000860"
     CDS             7203..7388
                     /locus_tag="IVD66_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HAP6145104.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            7455..7850
                     /locus_tag="IVD66_000861"
     CDS             7455..7850
                     /locus_tag="IVD66_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin HicB"
                     /protein_id="HAP6145105.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
     gene            7840..8217
                     /locus_tag="IVD66_000862"
     CDS             7840..8217
                     /locus_tag="IVD66_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145106.1"
                     /translation="MKSKKETEPMKATHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     ITFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKK
                     AKLLFEFQTDYHNELLAQSEILD"
     gene            8218..8613
                     /locus_tag="IVD66_000863"
     CDS             8218..8613
                     /locus_tag="IVD66_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145107.1"
                     /translation="MKQEKRKMKQTQTETINDTLADQLAGYYKLFEMSKAQRLIHYLW
                     KYKILFLFWEATLTFSVLFYKSDCYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVIS
                     DAGIDRNIKRVSFKITLNKPTDKKLSEAF"
     gene            complement(8919..9317)
                     /locus_tag="IVD66_000864"
     CDS             complement(8919..9317)
                     /locus_tag="IVD66_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin HicB"
                     /protein_id="HAP6145108.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(9508..10275)
                     /locus_tag="IVD66_000865"
     CDS             complement(9508..10275)
                     /locus_tag="IVD66_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAP6145109.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPNKLKKT
                     GEIVLPVKAIIKYMDVDQNLETELKNIVNTLQRQAVYEISNLDKEYKTYATVSAIDQI
                     HWDLEEQIITFNFSQEVIPLILSIKKKYPYFVFQDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LKIDFAKVRKGRNYNFAVQFNISSEFDEKPYREKKLG"
     gene            complement(10311..11534)
                     /locus_tag="IVD66_000866"
     CDS             complement(10311..11534)
                     /locus_tag="IVD66_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAP6145110.1"
                     /translation="MESYQFQVFKLVPSLERRGNRMKITEKNVNPKFEPTESNLKMFD
                     LTVTLSNQLVDSIVEMDAMPQKIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSS
                     SSKHSRLKQVIEKLHQQSVIKIQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSS
                     IMPLLTNLENHFTQYTFDQVVNLTSKYAISFFQLFTKNFNLYEANRDNLTWSTKSLDR
                     LKKPVFSIAELRKKFSIEKKYKAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTY
                     TDIKFLLTRTMSVPVPYKQEQRDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFL
                     ISSADLCDLKFMSRLQNKVYPLYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYL
                     EKSITSYLPYVNLYD"
     gene            12520..13323
                     /locus_tag="IVD66_000867"
     CDS             12520..13323
                     /locus_tag="IVD66_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAP6145111.1"
                     /translation="MSQEVTENVIDNDVDLVSDQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNVFRYLVKYDRREKDSFYSVLKALSDKLGTLTYRFE
                     DSDVYEQLWLFQKFRIDKQQETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFESFDYEKIYAKKGRKVDRLRFTFSEPESNLPSISMHNWLEED"
     gene            13930..14385
                     /locus_tag="IVD66_000868"
     CDS             13930..14385
                     /locus_tag="IVD66_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145112.1"
                     /translation="MDAINWHEFVNYMEKLLDDLKSFSIADAVKHGLPVSTTMKMRGL
                     KVPDEIIKLRTKTIIETAKIVDSMNLDLKGKKTTYEKDFVRFLKNVIGKYLGKKSFTE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIVEYLENKEQKKGTKKGR"
     gene            14504..15562
                     /locus_tag="IVD66_000869"
     CDS             14504..15562
                     /locus_tag="IVD66_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HAP6145113.1"
                     /translation="MEKDVNSASTKDQYNIIGGLLGDKDKRTRHGLRIMLATFLGVFL
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLTFARSGAEITISDVWTDKTRDVTVVKLG
                     YSGNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLDERAYQ
                     VFIANQVSLISGDYTADDDTKVNVNESDSVTKALSQYSMNDVDNEGVISFGKKAKPVN
                     TPDNINFRINPYSDTTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVNKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKTINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            15604..17553
                     /locus_tag="IVD66_000870"
     CDS             15604..17553
                     /locus_tag="IVD66_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAP6145114.1"
                     /translation="MENSTEFFKNIQTEFNHALTLMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAKRQRQEGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TIIPRLKEYERILKSEDKDNEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQL
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPEASLK
                     LSKKIPDELLEEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDIAKLEEELKSIKGQPVAVYTVTMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRKLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVNDTVSLSNAILFATTNAGAE
                     MYDSMNRYSSLSRVANQENSNEYSTELKREYRKVALEIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAHNEILKSAELVRKHLNVDLRLPPQKKHFYGQEFYADDLSMHLV
                     FDRASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSKAGGFEGKGDT
                     DAEIIAKPSIAESKENKFVFSVGGV"
     gene            17556..21245
                     /locus_tag="IVD66_000871"
     CDS             17556..21245
                     /locus_tag="IVD66_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145115.1"
                     /translation="MKFKKSLLQNRKIKRWVVRGLVIVGALAVTLGAPFGMNDPTSDD
                     QGNKQETVANTNVAYAESKPAEKGVWTLYARILMGDKEVNDSATKTGQMNLLGQGGIS
                     ADFPYSDISKQGNAIAGGNAGTQLASTLATYNYYGYIETVSGNAIASQASSFIGGIGR
                     TLGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGKGGSDVSNPVAKALTSLL
                     NNLGLNNQLFKAIASLSMLFFTAILGYQGMKLLSKEGVNSKGLSPVLEKWIVRIFVLF
                     VFLPVAGSLLGVYINGIQSAKEDGKLPTNVVGDYIINTRLWASTQNLAPSSDTGGNVP
                     NGKPTSEIKFVDTDYEPSKKSEMIRMINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NVNTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGNAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTTNNFDATQPWGVANNATFSTQSVALMLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFVRVWEVVLTGSLAAGAGVMAISLGVVTTSLIGLQLPIFLITFVRAFGDTAV
                     GFIPNTLLGDGVANIVRSAMVLGVGYLLVFKKGEKVNNNLINMLIGLPLEVAFGFDER
                     AKLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGRGSVKDMVAGGLGAVGAQGIAD
                     RLNNMGDSNADAKTIADKVVPETPASVPFNGGGVGGTINNTSFKDLVRQDQLRNNSQQ
                     YSDHLGRMVDEKGNFVDENGEVLKDSKFGKDAKGNFIDDKGRLVDEDGNLIDTNGKPL
                     EDNEDGNIGMDSQGRLIDDKGRLVDDEGNLVDENGRKLLNGDFGQDVNGRLVDDKGRL
                     VDEDGNLVDEFGKKLGKHSNGYNVNGDTVDEDGNIIDSRDALVADRNKELEQQQHTPI
                     AVAIPDDESDEVILDQAHQGLREEAKDKVVSDQAQEELKNKSNGEDVSNQYHQTAGNV
                     PVEGQSNELHNNFDNVADRNDTVLKEKESLRQETDKDQSKLKKTTIPTPIGSTVPKVN
                     QANDSETNTGLGMAKDNQSIREPKKTTESSKSNKSKSTSNKTGKSKEPSKAKSAVEYL
                     SKTGKNVYTSADKALAKAPKGSLAGMTYEAKNEAIKLGKGTAKVAKVTAKGATKTGKA
                     VKKSTMSVKDYIAKYSEQKPTDKKS"
     gene            21656..21994
                     /locus_tag="IVD66_000872"
     CDS             21656..21994
                     /locus_tag="IVD66_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145116.1"
                     /translation="MFDSIKNLVSGMTPEMKTLVQAILYLMATFFALKPGFTAMKHFG
                     DAKWGEGLKYVGAVVAIFIIPVITTVMLLTMGTKTGNDLNQKANMISALIPVVGIYLV
                     TKFPKEEQLG"
     gene            22106..22342
                     /locus_tag="IVD66_000873"
     CDS             22106..22342
                     /locus_tag="IVD66_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145117.1"
                     /translation="MDREKMLVHANEVLTSGFKGTDLAKIMNMNVNQFYDYRNGNKKI
                     EKARLETLIKFEKAYLYVLDKQKRTIDRKKGVLQ"
     gene            22342..24507
                     /locus_tag="IVD66_000874"
     CDS             22342..24507
                     /locus_tag="IVD66_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145118.1"
                     /translation="MAKFKDITESINYVAETVPVVVLSLKPQLLEVYQKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYVVIEDVQKLSSEEFPDEEDAILDSEKYVVLLKSSLN
                     YVVDLPEKFKEKLLAGVRFMDSNGQLLVIPDDPNMFEREVEEATDFYSAVDQLEVATK
                     GLERIAETFNSSDAVEFEAVAEAETEAVPDEEEALFEDNDEATEAGNQEASIEETQTE
                     TYQQPKIDEKPESQSDKENYVYEAEKIESESDVPKNLDADLLEKDFEQIIANKFQPVV
                     LDEVSDPVDLNEEMRSIAELKPLLFLAKESMNARISIANNKINSELNKTKEQLLLKGK
                     QMLADELLRIEEATSLSGQNQFTNTLSVAKESYEAEASKIDDLVMEKSSIIRKDYDMA
                     KQAYLEAELKKLEQRYDAEHLPEVKQQEDEFRKATEESLDQQYQEAIESIKNDALKQN
                     QEAKEVVVERIINSLKPEIEKSLTEVQEKTLEIVEKTKAENEAEFHDTKEKTTDVVVK
                     YFANKEEVEKLVAKDTNELESKLVAQQNIIEDYKNRVKEFKDLADGYKLNSQKLTEQS
                     EALREDLSRARNDLSQMAEKTKSLVVTTENQTESKRDFTSKKMATIIAVSAMACGTIL
                     GSSYFISHNHQEAQAQTETSISRVENSLGANTASTSTTDNNYEATPTTEFKVGEDVVI
                     SIDGKTTKAEVLSIDGDKAVVKAPDGNQYKIQAHLTEKN"
     gene            24519..24749
                     /locus_tag="IVD66_000875"
     CDS             24519..24749
                     /locus_tag="IVD66_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP6145119.1"
                     /translation="MREENIVYPVIENQANTKSSQLLQEVQVVYPVNELPQTNETVSK
                     SISLIGLLIVATALTVGVYRKLKVKGSISDGR"
     gene            24739..25605
                     /locus_tag="IVD66_000876"
     CDS             24739..25605
                     /locus_tag="IVD66_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145120.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVDWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLRFIFIPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNTARVTMGKKKPFRGTEILKVRQDGTIMYRDGSVALMFNLDGATSLTAFP
                     EEIIAQEGKSIQYQNARDRSLAEIKITSSQPQNTERQIRNMKVQKRNAKSNKAVFDIV
                     DQQERFVSEYIDGVKTTVIQYLILKSQSQMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSEIYALK"
     gene            25623..27581
                     /locus_tag="IVD66_000877"
     CDS             25623..27581
                     /locus_tag="IVD66_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145121.1"
                     /translation="MELMSRSKLLNFRKKKHKKEQNADSSKAVNNTYVSDLTSLVGYQ
                     FTPSYIRTGNRWGTIVKLVNTYGMNRNYEFGWMVKAIPEVKVEGVKAYLIEADKPVSQ
                     KDQQEIMHENVGGSTNSYENNLNDKNSDAEINKTVMRIIDLNTASLLDSTANKIIDWK
                     LEILLVSDSPDKISEQLIKLQRLYDEKMYGLKLMSFGGDQRDLFDRLLSEPVGSVYEY
                     TSMSSDFAGNDHAIRKGLDDADGWAIGTMSTSYASGVAFMAMDRSFKGKVLVASHKDA
                     TIKGYSEEISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGETFVAKPSLNSV
                     IEKINLAEEGLNSLELFGDRKDIGDLYRRNLDKLTQIFYLLADRELNPATRVLLKKEL
                     GNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEIDRII
                     VLKDTLRTALDSFSKMFNQRTTLKEIGKSDKLQIYYNLSDLRTEINVMEAQFLNTFDF
                     ITSQAKKGDIVMIHGFDRLSVETVGLIKKRLTMLEEDGVRLAFLFDTIGSGEDKDGIE
                     TADIFNTDGKIYQSFESDFNYTIIGKMTSEELMKYEKKVAPARKGEDDQKLSVDLRQY
                     LTSGRSNKFQIRRPVDLTNNFVIGEFII"
     gene            27763..28257
                     /locus_tag="IVD66_000878"
     CDS             27763..28257
                     /locus_tag="IVD66_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145122.1"
                     /translation="MNNLPEKNRVFRLKGDLSQFKLDENGEFFVWMRHEHCWCNPFEL
                     RKENEIRTKIENGEWDYLFRWSDESFIANNMDHAFVSFLDNTWGTWYDCYLKKLGFQN
                     IDIDAIECLKEVDNKYEEEPYYLLQQKLANDSAFQVEVWENEDGTYEGLAQEIPLSEK
                     KCSI"
     gene            28245..29354
                     /locus_tag="IVD66_000879"
     CDS             28245..29354
                     /locus_tag="IVD66_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6145123.1"
                     /translation="MFDLKKVYQHFLCISYITLFSFIFLFGVSVIVGTIFIWLTDEDM
                     SLKWFMCLLSCIMLVLLCLEVREFLPSHWQEKRKELREEIEIKTSDWMDHTWLPLKKN
                     IKQKEFWVLQLWALGKFCSYVALLIFDLIFYSIGIFGTAYYLLTDHNRLAVSDIFTVL
                     MTLIFVIQLSIFSQLLIRFIRQKITIDKLFRSLVDLLIISVILMTLTERIEQSGKTVE
                     GLKEFLTMFIQFVNGHMYLFVSGIILSMIGYVTTKLIKRSIEKEIEIDLIPTLSGYDY
                     YVNYGKFEELLHTNIVRTSIREFTNKEIKDSIHGEPTRKFIDRQKKVYNFYEVEAILR
                     YGIGKLWLEGRNIRQNKPYVFWKSGVLEQFPRRNR"
     gene            29375..29710
                     /locus_tag="IVD66_000880"
     CDS             29375..29710
                     /locus_tag="IVD66_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145124.1"
                     /translation="MKQYLNKWKVIEGSLVAQRIKGLPDCLEKDHLFQIREMLKKEQF
                     DPDQFLVVEYPTIGVYCCNHINDGKYFIIQEYEGQLTPFYTTWEMSEDGINNFPCESI
                     EESISQTEC"
     gene            29871..30059
                     /locus_tag="IVD66_000881"
     CDS             29871..30059
                     /locus_tag="IVD66_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145125.1"
                     /translation="MTSEELMKYEKRVAPARKAEDEQKVSVDLRQNLTSGQSNKFQVR
                     RPVYLTTNFVIDPQTFGC"
     gene            complement(30663..32258)
                     /locus_tag="IVD66_000882"
     CDS             complement(30663..32258)
                     /locus_tag="IVD66_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145126.1"
                     /translation="MFILDDEINKVKNPRIIPLLEEVRSSFYQGNYRSAIAVNYSALV
                     LDLIDKLSDLANIYEDDTSKKILEEIAKLRKKDPNSPRWEMELLEKTYNSTELIDSYE
                     YEDLKYIKDQRNYSAHPVVTYNGDTWELREITKETCQDVIRKSYEIVFLKNPILGKKV
                     TNEIIQYASRIHSMSVTPEEFHSALKNSYLKKLSEKAKENLCKTAFKFVFKLPYGNEE
                     VDRDRVSTFRLLDALIFDSKEFYLKILKKEISNYRFTAESREEINKSLGENQQITYTK
                     GFFLLTFIASHPELQRDFSEEIIQNLKISIKDFEPKQPITTHIEDYYRLRSLAVLGNT
                     KKELQEHLNRLLDPILQQNMRVSSLATSTLETIYNQYLYFGEKEMFLDFMIEHLTDSP
                     AFKFSDKDMEVLPWIYDKLNQDKFNKLLYNLNRNNQFYHNGYFSSFISNLLDFYKQKF
                     HMDLRTHYNGLLYPNAVTMDQKFQLKDKELKKLYELAESKSDTYPEILNDLKLNLITK
                     SEQYLGEKINSEEKLLDYIKQIK"
     gene            32380..32964
                     /locus_tag="IVD66_000883"
     CDS             32380..32964
                     /locus_tag="IVD66_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145127.1"
                     /translation="MGLKQSVYIWLYPDNPMSIMADIFVGSILLCLLYLIFFHNLIGY
                     MILDWKGMFDIERKPFNNKQTYTTFAGGDLEEKEVDVTHEIGLALSGIQDAVALGSMI
                     TDTGYNAYEVFYLMYFIWRDSQDIINGRAEKTIISNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
     gene            32975..33226
                     /locus_tag="IVD66_000884"
     CDS             32975..33226
                     /locus_tag="IVD66_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145128.1"
                     /translation="MKKIIDQPTNRLIVEGVIFVTMYFTVGNGISNTIIQKDPQYLLF
                     SLYAWIVQMLWVSLLMLLFYWIVRVILLVLNKAKKKKDR"
     gene            33233..33955
                     /locus_tag="IVD66_000885"
     CDS             33233..33955
                     /locus_tag="IVD66_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145129.1"
                     /translation="MKATKLKLVLFSTAVLLTLSACGTSKSADNTKDTKSSSTVVTES
                     SSAQTSTTMSSMTENNAEKFQKYKDVNQGKKPEEVYNEFISSVKNDESYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIQEGFSYAPTLMHDITIGKPAYEYHAVAVDITDGV
                     PEWVQNIPGLADENNQYHTPTLAVVTPKKIDGTLYWDLMGMTTNTSDEMIESTSNYYM
                     DLGAYKSYQQSEPVMDDQSTIK"
     gene            34085..34828
                     /locus_tag="IVD66_000886"
     CDS             34085..34828
                     /locus_tag="IVD66_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145130.1"
                     /translation="MKEISASEAHISQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKATSIRELRSEVEKIRLGLTSEEIAKLKGNNSFVIEKEKEKHLLYRELKIEEYYEI
                     DLPEKLRIIDQRSEEKWKTEIYPSLNDYKTSGKPMYNYTGFLTYTQYKYAFRKLKGIK
                     QAEIALYEMKKVDRLKLIQELVQNTWNQAIVELEKENGKILTNKYLIVNEIEELIGLF
                     SCEKGEVFLKSSPTYSILDSPYQFIQARR"
     gene            34834..35199
                     /locus_tag="IVD66_000887"
     CDS             34834..35199
                     /locus_tag="IVD66_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145131.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDRQFNQIHHNIILLVEQAKRRFEKAEYDLLDQGIVCLDKGLRRYYGAELKKQ
                     NVDRNALKHEILELIMQRI"
     gene            35215..35745
                     /locus_tag="IVD66_000888"
     CDS             35215..35745
                     /locus_tag="IVD66_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145132.1"
                     /translation="MSQNISAVKQLIEEDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAEEKSSILELSQ
                     NDKVIQVKCVDPTGKIIVGFDIERKSKIDFITQLKKINNLDILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFPNA"
     gene            35907..36296
                     /locus_tag="IVD66_000889"
     CDS             35907..36296
                     /locus_tag="IVD66_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145133.1"
                     /translation="MWNNRLKTGLLLIVISCAMMIGMRIQREQSYFEVSANNVIEKCY
                     YGQHYWSEEVRENIDREYVQRIVWDAYSIKDYPKSLTSRLFYSEKDNQKLSDLMMKKV
                     RKLAQSYLEEKAGAIKDKEEMEKFAIE"
     gene            36289..36678
                     /locus_tag="IVD66_000890"
     CDS             36289..36678
                     /locus_tag="IVD66_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145134.1"
                     /translation="MNEKTELFLKKVNFLVEKYFLTKHKIMYLIKGLIGGIILWILTF
                     FSLFGGFTNYKKLVDENVKQISASESLRHQAEDLVSNPLFIGGMVEVIIISFVIGYLG
                     MCIFQIIFDLIRGKVFQGFKFEKINLR"
     gene            36708..36932
                     /locus_tag="IVD66_000891"
     CDS             36708..36932
                     /locus_tag="IVD66_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145135.1"
                     /translation="MEQTNHITEETRKFICLESFYSEGRYCNKGETYTAYPIEGGFKL
                     VFENGDMNFTTELFECVVETWSDVLLEVTK"
     gene            36985..37245
                     /locus_tag="IVD66_000892"
     CDS             36985..37245
                     /locus_tag="IVD66_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145136.1"
                     /translation="MAYENLQLVVAGVSGDIYLAKAKDGIMDTNYRRVATDDVLSSAT
                     EWFRTNEESAVHFKGIDGNIHSLFYTKDKEKAKKILDILKES"
     gene            37584..39824
                     /locus_tag="IVD66_000893"
     CDS             37584..39824
                     /locus_tag="IVD66_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145137.1"
                     /translation="MSKYEFLDINVGSAFLINLDMFEAWAQSSGYNWAFSDDMIEFLS
                     RTMSWESYKVKQFLDVIAKPIYTSADDHWSGRELATLKELAEYNKNYNIPFQVSYTTD
                     DFSVIYALGKESRYLIPNRYLEIKMNSDYTNYTLGELKALRQSDSEEFSTLKNEVSTE
                     NFRISDIEELKKQQKQQLEKQKKLIEDIAYKRVDELAVQEAKIEKMRQELYEKQQSML
                     AEANKMRFELEKKVEELNTKIFYLETEIDAIEGYFGESTTFVQLRSGQKSLPEDPVVM
                     FQKVRYLDEELGRYFSMREVEGTADTMLTFEQALSSRDDLFDLFSPNKKSISMIRISK
                     SGYGYTNGQMESTNMLEKYKKYHGETLAILLRNGDNLWICWLDENKISFKDDLFYQNK
                     VTEQASETKNMVKEIDWTHTRNLEERLKDAKKQKRAVRGEFASRYILFSILQGVLDNG
                     TMMTLPEKVNVIQAINQKSPYFIASVADGWLEDTRLPSFSELIDKYSFYKETGEDRVL
                     EAEYELNPDKFENMRDYPHKQNDDIYVLYRLRGWSPTSANYTYYNSDNRSNSESGRDL
                     AYSIDLKDGIYQINLVKQGKFQKQMFSRTFVGVDSTTGENIYDYYYERETEYYIRGQK
                     AYNKSDYWGDKAKRLTANFRVYESEFINLTFLNSVFIDYVITTKRIGSYSSTYASLVP
                     MLNSMSRFLKEREEKELQYIKEIMPDFEMHEWQIALSDWKLTNKVRRITPFQAKRFLK
                     AMKFVQ"
     gene            39962..40759
                     /locus_tag="IVD66_000894"
     CDS             39962..40759
                     /locus_tag="IVD66_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145138.1"
                     /translation="MSEDLRELKLRKKQYDQYFSGLLNKHIEEGLDHDFGKDEYCLYC
                     ERYNEKMSEYLQLKKKIQKLEKKVHAWKYKDSMSGYGESQNKPRKKKQAYVLKMVNGE
                     ELIVLAYSKEEVRELVETPVRKKIETINEIDDSQYNSIYIETSHGGYKKLATFLRSSK
                     VGIISKKDISAVTDSFCTLSVPKAYLQYNSNRFERLEKFCRPYTVLKTKKFNKTKRVS
                     IKLPTGQISLGEKDYLIKVGKELIIKVPERLFKENFEIRETLVWKEE"
     gene            40799..40981
                     /locus_tag="IVD66_000895"
     CDS             40799..40981
                     /locus_tag="IVD66_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145139.1"
                     /translation="MAVNRKLQVLITDDFGGAEWFDVQSIDFEEEVVVIENVYGEEYS
                     YSLEGENVEDLRLIGE"
     gene            41025..41312
                     /locus_tag="IVD66_000896"
     CDS             41025..41312
                     /locus_tag="IVD66_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145140.1"
                     /translation="MINKKTGKRIFSSKDEVIRDLSENFEPIELFFHQLNLEIEKLLK
                     EPTEGRINKVLKLIACKDSHAYMLYPKWYADKNIAEINDYLASIKERNAIN"
     gene            41349..41636
                     /locus_tag="IVD66_000897"
     CDS             41349..41636
                     /locus_tag="IVD66_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145141.1"
                     /translation="MAEVKFGSKEWFEELNSMIQFPEKFTFYYNKRDNIIQVALLETK
                     GRLENTRWSMIKPSALRFHPKDLTAVVAVKEVQDSQEYYEVVKNLKDIWCK"
     gene            41727..41966
                     /locus_tag="IVD66_000898"
     CDS             41727..41966
                     /locus_tag="IVD66_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145142.1"
                     /translation="MKELEGIKKRNQERLELLNENRNRMFSYYESMRCLNKSRSEIIE
                     SSKYKQLMEERVSLIQEIETESIFPDHFPKVRFYN"
     gene            42094..42423
                     /locus_tag="IVD66_000899"
     CDS             42094..42423
                     /locus_tag="IVD66_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145143.1"
                     /translation="MKLEGSLQNRMMEGRTTNKEIVVGMGATELLYTDRNPYTVIEVK
                     SKNRILVQADGAINKATFPDQEWEYSRNPEGQILELIKTKNGWKVLKENTHFYIGDRE
                     KYYDPSF"
     gene            42476..43324
                     /locus_tag="IVD66_000900"
     CDS             42476..43324
                     /locus_tag="IVD66_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145144.1"
                     /translation="MFSQEEIISKSQPDKNGTITMKKKIPCYRCSGSGQYKFMSMGKI
                     TYGTCFKCDGDGFLVVTEKSFTPEYRAKLNALNKKRADRKIRITREKESQKNFDRYGF
                     EKGYIYVVIEENSYAIKDELHHQGATYDPLLGWFFKEKQEQYKTQKVFVEEFSVINDE
                     GIIELKLEEYSERQQEILRAKRREEGEFIGTIAQRLELDLKLTNTVTIDTQWGNVYLH
                     LFEDQNHNSLIWKTNKFLYYDEWDVGEIRKVKATIKAHDYYRDTKQTWVKNVKIQKNE
                     SEGIKV"
     gene            43321..43638
                     /locus_tag="IVD66_000901"
     CDS             43321..43638
                     /locus_tag="IVD66_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145145.1"
                     /translation="MKREEYKQRLNELLEEDETLTHGSPDEILYMIDNMVIFGGYELG
                     NRSVDHNILEFDDVSWEEILDWGILAVPETKTYISDTMVPFFEELDYKRLPKNENHIL
                     GGN"
     gene            43641..43874
                     /locus_tag="IVD66_000902"
     CDS             43641..43874
                     /locus_tag="IVD66_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145146.1"
                     /translation="MLSDLFILLIYLGVSEIIAYFLFVIANYGISSAIFQRFRLPVSE
                     LKKMMRLSAYLLMFLNVVTLIFVVIGVTFNLME"
BASE COUNT        15881 a         6409 c         8222 g        13451 t
ORIGIN      
        1 acttttgttt tgtgttaagt ttctttatat tactacgccc attatgtgta aaatttcttt
       61 attcatccca cgctccatgt tattttatat ttcctttttc atgttatttt tcgtcagaaa
      121 ccgatctagt ttttacctat tcccaaaatc catttattcg ttatttttta ccctgattaa
      181 ggataattat ttgatgctta aattagctaa aaaagcgatt tattgccgat ataatcatga
      241 tattaaagct gaattaggcg gaaaggcaaa atgttcgcaa aatcgaagtg tcaattatct
      301 tgttttttta taaattttta agtgaaaata tgaaaaattc tcttttaatt ggtataggta
      361 ttaaaattac ttttaatcac tcataaaagt atgcgctttc atcgtttttt atgagaataa
      421 tatcaataaa taacgatata aaaaccattt ttgatactgt tttataagga tataaattga
      481 tctaatttag aaaaataatt caaaatttaa aggttttaat attacaaata gaataatgtt
      541 atcgtaaaat ggtataaaat agctgaatat tttatttttg ttattttatt agcagaaaca
      601 tctaaataat tatacatgaa tccatagaaa tatattggtt tcaccttcag attaatattg
      661 gatcatatta atctgaatat aatatatgaa ctaataaata gcttaacctc gctattttgt
      721 tttttctgat cactacctac acagcattag taaatagaat ttaaaaaata aaaaaattaa
      781 gacaaaaaaa gtatcaacat aaacatatac atatacacgt ttatgttgat acacttaatt
      841 tgtcctttaa aaagcattaa ttattgaatt atgttatttt ataatttgat tacaagctga
      901 ttgttaggtg ttgtccttga attacatttt tcaacggtta ttttatcgtt taatttatta
      961 attatttttg atctaaaaat taccttaaca aatatataat taaccaaccg ccagataaaa
     1021 atgcgatcat tgctaataaa taagcaaaga taaaaatatg ttcgatcagc ttaaaccctg
     1081 atgcgattaa gcagaccaag taaaatagaa attctcttac agataatggt aattttctaa
     1141 ctagcatact cataattaac accccaaagt aatattgtat tttgaacatt ttacatccaa
     1201 tacagcatca atcaaccatt gccaatcaaa aatgcaaggc ttcattgaag tatgtttttc
     1261 agatgaaaag atataatata atttcttcgg aataatattt tcagttgttg ggatcaagct
     1321 aaatttaata ccatctaact catagctacc agctttctct ccattaaaaa tttccttagc
     1381 actttcttct aaagaatcaa aatatttttc gacagcaacc tttgaagctt ttactattga
     1441 agcatttccc ttttcgataa aatctgcttt tgttttaccg acaataagta attcttgatc
     1501 agtaaaatct tctaaaataa tagtagtgta attcttattt cttctcaatc gcatcaggat
     1561 cactccttaa tataatttat gtttttataa tatcataata tgataaattt gcaagtgttt
     1621 atttacacct ttttacttac actttattgt aattgattat acttttttga ttgcatttct
     1681 ttcttataaa cagttgcaac tattagtaaa taggtgtaaa ctattttcgt accgcaatac
     1741 cataaacaca aacagaaaga ggtcatacca tgaaagaacc attattgttt tccgttgact
     1801 tagggaataa atcagtaaaa gaaatgagta cacacgtttc tccactctcg cttccctctc
     1861 gtattttgaa caaaaatatc attaattcag gacgtttttc taatataggt tcctcattaa
     1921 aacgatcact aaacgtttct gaatatagcc tagtaaacac tactgaaagc tattattttg
     1981 ggaaggatat acacgagcta ggaaaagatg actacgtgat agaatcacta ggttttggga
     2041 tcagcagata caagcaggaa acctaccaaa atatcctatc tttctcttta gctaacctag
     2101 cacgtttaga agatcaatct gatgacgttt taaccgttaa tctagtttta ggtctgcctt
     2161 catccgacta taccgaaaca atcgtcaaat acgtgatgca acaagccaca cgacaacatt
     2221 cagttgaagt tgacggtaaa gcttataata taaacgtaga taccgtttgg gtactgccac
     2281 agccgattgg aacactatat aacctcctcc ttgctgatga tggtagtgta caagatgaat
     2341 cattgatcag tcagaagatt ggttttgttg atattggtgg tggcacgaaa ctttttgatg
     2401 ttgtccaaaa ttttgaaatt gacgaaaaca accgtgaaca aaaggatacc ggtattttta
     2461 ctttatataa tcgtatcgta aatatgcttg accttccgat cagtcctaat gctttccaac
     2521 ttgaaaagat tatccgagaa ggcaaagaaa aaggcgtata tctatttaag ccaagcggaa
     2581 atgaaagttt tgatatttca gaagtagttg aaagagaaat aaaaacatac accaatatgg
     2641 ttgttgcaga agttttagct acattcaaaa acttcacaac cttagataaa gttgtcttta
     2701 ctggtggtgg ggcttctatt atcgacaaac aacttgtaaa agataaaatt ccgcatacct
     2761 tgtttgttga agacagtgaa ttttctaatg taaaaggctt ttacaagttt ggtttaactc
     2821 aataaaacag cgaaggagat caacatgaat aagggaaaat cagagcgtta tgtagttata
     2881 atcaatagag aaaaggttag cgagttacct ttagcagagt ttcttgaatc tgaatatgaa
     2941 acactaggcg ttaaatactc tcagacgatc aaaaaagctt tgaatctata tcggcgtgta
     3001 aagaacaatg aagttacaat tattgaagca ggcaacgata gaaacgatag caaagtagca
     3061 gaagtaaaga ataaaccaac tgatcataac cctattcaac aagagcatcc ttcaacggtt
     3121 acatccgatc attcagcaaa gaaagaaaag ccaatgctaa aagggttcaa tgcaccaagt
     3181 aacaaagact tactttaaaa ataaaaaggc gaggttacaa tacctagcct ttttattatg
     3241 taaaaataca aacataaaca tatacgtata catgtatata aacatgtata cgtatatatc
     3301 cataaacacg tatacgaaat ttagttaagc tatacctaac cgcttattcc aataaaaaaa
     3361 gtgatcagct ttaaactgat cactcaccaa aaacttcatc atacaagtta tctatcattt
     3421 caccaagtaa agctgaatct gatcgaattc ctaacttttc gctgatttta gatagtttct
     3481 ttctttgtga tggttgaagc gtgaattgat aatttttctt cttttcagaa ctatcacttt
     3541 ttagtttagc taccaaagaa cttgttgttt ctttaggtgt ttgtttaggt tcttcaactg
     3601 cttcaaccac ttcaggaact tcttctactt cagcttcagc gaatttttta aatctatttt
     3661 ctttcacttc aatcactcct tattcttgtg ccgtatcaat tattttgttg tatagcgtaa
     3721 acgtgctttc aaagaaatcc ttattcttac gatagatatt cttatcctta gcgaactcag
     3781 caatattctt accttctaag ctagttgcat taagcaattc cttctcttgt acatatccaa
     3841 gataattaga taacgttggt accaattcta ggaactcacg acttgaatta gtattatgtt
     3901 tgatcctgct accgatcgta gcgtatttag tttccatcag tgtttcacca gtcttaatat
     3961 caatcaactg ttttgctagt gcatcaatat ctttaccaag cttcagtaaa gcttcaaaac
     4021 catctttaga tggatcagaa atgcctacga caagatcaga tacagcccaa gcattttgag
     4081 ctagtagacc tgcatcatta tgagtatcaa tcagaattag attatacttc tctttaagct
     4141 gttcatagtt aacaacgatc catctaaaca gtagggttct gttgttaggc atatcacgca
     4201 tttgcatctc aacttgtttt aaatcttcac ctgctactaa aatatccatg ttctcattta
     4261 tagctaaagg ttcagctgat ccatgaagat ataaatgatt gattgtattc tctcttttcg
     4321 ctttactgaa agcatcagga aagcgttttg ataggttttg cgacttatct tcatcaatat
     4381 acagcacctt catacctaaa ttttcgacag catatccacc tagattgtag attgttgttg
     4441 ttttacctgt tccacctttt tcaatgtttc cagtaatgat tgacaacttc ttttccatga
     4501 ttaaacctcc cttattaaac ttttgtaact ccattataca ctataaacac gtttatgcat
     4561 atgtttatat acataaacgt gtttatattt atatttgctt ttatattcta caacataaac
     4621 atatatatgt atatgtttat gtttatgtat atgttcatat atatagctat tgcatctgtc
     4681 atacaatcgt agtacaatgt aattgaaaag gagttgataa actatgccag taataagtat
     4741 tcgtgtatct aaagaagaaa aagattttct tgaaaaagtt gctgaattca acggagataa
     4801 catttctgaa tttatgcgta gtaattccct gcaaacagca gaaacgttag tagactttgc
     4861 cacctacaag gaactaatga aagagcatga ggaaaacgat caaagtattt cccacgaaga
     4921 tatgctaaaa gagttaggct tataagatga gttaccaagt aagatatgaa cgtgaagctc
     4981 aaaaaacgct aaaaaaaatg gataagtttc aggcaaaggt tatcctaaac tggatcgaga
     5041 aaaatcttgt aggcactgat gatccaagaa agcatggtaa aggtctaaca gctaataaat
     5101 caggctactg gcgatatagg gtaggtgcat accgtataat agctgatatt agcgagcatg
     5161 aagtgacaat tcttatattg tctattggtc acagaagtga agtttataag taacagacaa
     5221 gctgataagg cttgtctgtt tttttgttaa cccaacaaaa tcactgttta cgatcccact
     5281 ttacctaaaa aagaacaata tcctcttgtt attatacaca ccagtgtgta taatataagt
     5341 gtaaacaagc taattaactt tcaaaaggag cgatttttta tgggatggta tggtgcttat
     5401 tcatcagcaa ataaagtaat cgaagaaaag aaaggatacg ccaaaaatgg tttggaaatc
     5461 gtagatacca aagtaacgaa gacctatgga attatccttt tcaaagatgc agaaggaacc
     5521 tacgatattg acagcttcat ctttcgagat gaaatgtaca aaccaatcta cttcttaaat
     5581 gacagtcctg cttactttaa gaaaattcca aaaaaatggt tgaaattctt tgtcggtgat
     5641 caagaaaaaa tggttaagcg acaactagat agaattaaaa aagaaagcaa taaaccaaaa
     5701 cttgatgact tattagttgc aggtaaaact tactcaatct gggatggatc gtatgtcgct
     5761 gtttatcagt ataaactcaa acgtagcttt atttttcgac tacaagatgg atcactcact
     5821 cggttcactc gactatcagc aggagatgtt aaggaagtat cctaaaactt aaatacataa
     5881 acgtattagg tacgaacgct tttaaatgct tttctgggat ttgattttag ggtagggcta
     5941 aaaacatcac catctgatcc aaaacagctc agaaacgcat ttaaacgtat ctgataccaa
     6001 tattacagaa ggagtgtatc gtatgattaa cctatttctt ttagtgacag ctagtacatt
     6061 attctttact ggaatatcac tgataatttc ctatttgatc tataagaaag ccgaaactta
     6121 cacaagcaaa gcaaccgtac tagctgtttc atccttttta actttgctga ctttttttgt
     6181 tactctatca ttttcttttg tttagcacag ctgatccatc agcaaaaaac ctctctttac
     6241 attatacaca ccaatgtgta taatgtaatt gtaaacaagc taattaactt ttaggaagga
     6301 gtgacaatat gctaacagct acattacagc aacctactca cgttgctatt gcagaaagct
     6361 atacaattaa tgcaggggtc gttaaacagc tgatcaagga tcgagaattc aaaaagttta
     6421 atagtcgtca agcgtataac agacagttaa agaaagctat tctaaagcac aaaaattcct
     6481 tcatcgggaa attggaaagt gtggatgtta aaactgtttc aacggcattt tcagttgttg
     6541 aagtgactat tgacggtcgc ttgatttctc tatttgcttt tggaattaat tgatagggag
     6601 tgtggacttt ggaaggtaag acttttgcag aaatttggac tgaatttatt gaggtaccaa
     6661 ctcgcattga tccgataact tctgaaaagg tattggatgc agacttctac aatctcaaag
     6721 caggtactag ccttgaatgc gtttggatgt atttagaaga gcatttcaaa ggcgtaacgc
     6781 tcggtcacgt cttataccac aatggtgcgg agtgggatgc aattggaaat atccattttt
     6841 cttaatacaa gaaaggagaa cacaatatga attataccga tgaagaacaa atcactttgg
     6901 aatacgtttt cacaaatgaa aaaggggagg aaattgaaaa agtcttgatc atttcatcaa
     6961 aagacttgga gaacgcttta gcttatgaac catacgaatc aaccgtaact gtcaatgaat
     7021 tcttagatac ctatacttct aatgatactt gggaaattat gaatatttgc aatgctaata
     7081 acattcaatt tgctgaaaaa accaataaat cattttatta gttttgcaat aaaacatcct
     7141 ctttttctat tgattccata cacaacgatg tgtataataa gttttgtaaa gggagggtag
     7201 ctatgcctaa gacagcaaga gaaattgtaa aaattctcaa atctaacggc ttcaaaaaga
     7261 ctggacaaac tggcagtcat gcaaaatttt ataattccaa gactaaaaga acggtcgttg
     7321 ttccgatcca caatggtgat gtaccactag gaacagaagc taatatctgg aagcaagcag
     7381 ggctttaaca gccttgcctt cctatttggt attaggcata ctatcctctc ttacactaga
     7441 aaaggagcga ggaaatgaag acaaaaaata ttttttatcc ggcaatcttc gagaaagaag
     7501 gagaagctta taacatcgtt ttccctgact taccggaaat atctaccttt ggaaatagtc
     7561 ttgaagaagc atatttaaac gctaaggatg ctttaggatt agcgctatat agtgtaccag
     7621 atgcagaatt tcctaaacca tcagcagtgg aagaattaac tttgaaagcc aatcaagtgg
     7681 tagtaatcat ccaactaaac attaaacttt tccgaagaag cttaaataca aaaacaatta
     7741 gaaaaaatgt tagtgttccg gaatggttag ttcttttagg gaaggagaaa aacataaact
     7801 tctctcaact acttcaaaaa gcactagaag aagagttgct tgaaaagtaa aaaggagacc
     7861 gaacctatga aagctacaca cttaaactat ttctctcgaa cgttaatcaa taatctatta
     7921 aaagatacaa ctggcattag cgttagtacc aaacactttg ccaatgatct aattactttt
     7981 gaggataata acttgcgaat tgagatgttt attgaacagg caacccctaa ctcaatacct
     8041 gaattctgct atacgcacac tgaaaaaatg aaacatgcaa aatcagttaa agatgttgaa
     8101 gcattaagtg aatcactaac gaacgcttta aacctcgtta agaaggcaaa attgttattt
     8161 gaatttcaaa ccgactacca caatgagttg cttgctcaat ctgaaatttt agattaattg
     8221 aaacaggaga agagaaagat gaaacaaaca caaacagaaa ccattaacga tacgcttgct
     8281 gatcaattag caggatatta taaattattt gagatgagta aagcacagcg cttgatccac
     8341 tatctttgga aatacaaaat tttgtttctt ttttgggaag caacactaac attctcagtt
     8401 cttttttata agtcagattg ttataatcaa cacttagttt tagggagttt tttgcttatc
     8461 tacaccattt tgatgcttaa tttatatacc tacatcacac ttgaagaaca cttagtaatt
     8521 agcgatgcag ggatcgatag aaacatcaaa agggtatctt tcaagatcac gttaaacaag
     8581 cctaccgata aaaagctctc agaagcgttc tgagagcttt tgacattttc ttgtataatt
     8641 tatccaaaca cattacaaag cacctaattc gagcttatat caagcaaatt tgctatttat
     8701 tcctcaatac atatctaaaa attacttgat ggaaaactag atacatggta agcatgaaaa
     8761 gaaaatcaat ttgagcagat gcagtataat acatagcaat ttaaaagctc tcagaacgct
     8821 tctgagagct tttaatatat tctttgataa tttgtctttc ttaaatccat acgtcctaaa
     8881 acaagctgtt tttgcttaat atgatcatct gagagacatc aaatcaactt ttctctcaac
     8941 aaatcattca aagctttcga cagattaata ttctcttcag ccgctaaaac atttaaatag
     9001 tgttccacag tcactgattt tcgatcgtaa ttttgcttgt ttcgagcttt agcaactttc
     9061 gtattagctt ttacgacaaa taaattaaca ttctcagatc gcttgattct tgcatttaac
     9121 tcttgaacag gcgtaggcga tggaatttct ttttcttgca actctaaaag caccaagtat
     9181 ccttccaata cttcttgcgc catctcaaaa gcatcttcta aagtttcacc atgcgtatat
     9241 aagtctggaa aatctgggaa tttaactgca tattcatttc ctttccattc gaatactgca
     9301 caaaaaaagt atttcatcgc attgcacctc tctaattaaa aaataatttt tgctttttag
     9361 tttcaaaaaa agaatcgcct accaaaaaaa ttgataggcg atcacaagct aattaacctc
     9421 taaaggagat taataccttg ctcccaaggc actacatatc ttagcatacg tctgaagcat
     9481 cttcaaacga gtaagatata ttttgcatta acctaatttt ttttctctat aaggtttttc
     9541 atcaaactca ctagaaatat taaactggac agcaaaattg taatttctgc cttttctaac
     9601 tttagcaaaa tcaatcttca gcattgattt ttcattaatt tcctcaactg attcccttaa
     9661 aacacgtcta tcaaaattcg atattgtttt gtactcattt tctgttttcg taatctcacg
     9721 aattttaact atttcaatca ggggattctt atatatttca gctttctcaa aatctccttt
     9781 atttttggcg ataagatatt ttttataata catcgccaaa tatttgtata acacaatgct
     9841 atattttttt tgaaagcttg ctaaatcttg aaaaacaaaa tatggatatt tctttttgat
     9901 tgaaagaatt aggggaatta cttcttgcga gaaattgaaa gttataattt gttcttctaa
     9961 gtcccaatga atttgatcaa tagcagatac tgtagcataa gtcttatatt ctttatctaa
    10021 gttcgatatt tcataaactg cttgtctctg aagggtgtta actatatttt ttagttctgt
    10081 ttcaagattt tgatcaacat ccatgtattt gattattgct ttaacaggta aaactatttc
    10141 ccctgttttc tttaatttgt taggagagat ataactgaac agcaattgat aaagttcata
    10201 cgactttaaa tccattttca tgtcaattgt tgctaagaac tcctcgttgt actttgtcag
    10261 ttcatctttt ttcaaaagct tttccttcct tcacgcaagt ttttcagttg ttaatcataa
    10321 aggttcacat aaggtaaata actcgtaatt gatttttcga gatatttaac agtatttttt
    10381 attgtgtaat cctccttatg agtagcaacg taagatagat gattgacaac tgattcaaat
    10441 cctctatctt tggataaacg atcataaagc ggataaactt tattctgaag ccgactcata
    10501 aatttcagat cgcataagtc ggcagaactg atcaaaaagt ttttgattag taatttagtg
    10561 tatttgctat tcatagcttt caagtacgat tgattcattt tctctgtttt atcttctgca
    10621 ccttttaaat aagcagggtc tctttgttct tgcttataag gtaccggtac tgacatggta
    10681 cgtgtaagca agaactttat atctgtataa gtatgaccct tcttgataag ctcatagtca
    10741 attttaaaat cagtgtattt attcagttgg gcaatcggtt ctttaattac acgtctttca
    10801 aagtctcgaa aagctttata ttttttctca atactgaatt tctttcgtaa ctctgcaatt
    10861 gaaaaaacgg gtttttttaa tctatcaagt gattttgtac tccatgttaa gttatctcta
    10921 tttgcttcat acagattaaa atttttagtg aataattgaa aaaaactgat cgcatatttg
    10981 cttgtcaagt taactacttg atcaaatgta tattgtgtaa aatgattttc taagttcgtt
    11041 aacaaaggca taattgaact actaaattta atagatactg catcagaaaa atcattgaat
    11101 tcagtaattt ctagcggtga gatgactttg tattcagtct taccgttagg tttagttctt
    11161 tgaattttaa tgacagattg ctgatgtaat ttttcaataa cttgttttaa tcttgaatgt
    11221 tttgaagaag atgaactaga agacatcaac gcaaataaag cctttttaga tactttgacg
    11281 gtattattaa aaggcggatt tttaggatca agatgtccta tagcgtaaag ataaattttt
    11341 tgtggcatag catccatttc aacaatgcta tccacaagtt gattcgataa agtaacagtt
    11401 aaatcaaaca tttttagatt gctttcggta ggttcaaatt tcgggtttac attcttttct
    11461 gttattttca tacgattgcc tcttctttct aagcttggta cgagcttaaa aacttggaac
    11521 tggtacgatt ccattgaata agtatagacc tgttttcgat acgatacaat aagaaatgta
    11581 tcgtaaattt ataacataac tcaatctcag taaaacgcat tttattttta ttaatcaaat
    11641 ttcattgata agacagcaga aatcgctatt ttagaacctt tacaaaataa aaatcctttt
    11701 caaaaaaaat acgtaattat aaaaattcac aaaattaaaa aacaaatatt tttttagttt
    11761 ttagaaataa attcacatac tttgtctttt tttgtatata ttcggaatac cacatcgctt
    11821 tttgtccatg tttgcatcgc tttttgtcca cattcacatc gctttttgtc catgttcgca
    11881 tcgctttatg tccaccctaa aatctattta agattgatat aaagcctttt tggagattgc
    11941 taaagtttta aagattaaaa tatatattat aaatataaat aaaaggggaa gctgaagctt
    12001 cctccttttc ctttttttca attattcaaa attacacaag caaaataaac tgctagatag
    12061 tgttagtttt ggttttaagg tttttaattt ttgagatttt gaaataagag aggaggaatc
    12121 ctcctttatt aaatatctgt taatatatct gttaaatatc tgttaatata tctgttaggg
    12181 gggtcttaac cccttgggag agtaagtatt gaaggggtat gaaggtaaca cttttggaca
    12241 gtaagggtaa caaaagtgga cagtaagggt aacatttttg gacagtaaag gtaacaaaag
    12301 tggacatttg aggtatcaaa tcaggataag acgttacctt cggttttctt gatttgaaaa
    12361 tcgaaaaagt agaaaactag attagtaaca aatctttgtt gactgttacc tttagttgtg
    12421 atttaattta ggtaacaagc agaaaaaaag cgtttccttt aatttagtac caaattaaca
    12481 tgattaaagg gatgcaacaa gaagattgga gagtaatcaa tgtctcaaga agttaccgaa
    12541 aacgttattg ataatgatgt agatttagta tcagatcaaa caaatgcaat tgtgcgttat
    12601 aacaatggtt tgaacacaac agctttgcga ggatttaaac ctgtcgaaat ggatgtgttt
    12661 tgggctattt tatcaaaaat gaaacgtcaa ggaacagcag aagtaacttt tgatttcaac
    12721 gtctttcgtt atttggtcaa atacgacaga agagaaaagg acagttttta ttctgtgtta
    12781 aaagctttga gtgacaaact aggtacttta acctaccgct ttgaagattc agatgtctat
    12841 gaacagctgt ggctttttca aaaattccga atagataaac agcaagaaac agttacaatc
    12901 aaggcaaatg aggagtttga atttatctta aattcaattg gcaaaaactt tactcgtttt
    12961 gaacttgata actttacaaa actaagaagt agctacacaa aagagctgta tcgtcatctc
    13021 atgcaatata gaaataaaga gtggcgaaat ggctattggg tagtcaaagt tgaagatttt
    13081 agaagagcgt taagtattcc ttcaagttac agaatgacaa atattgacaa aagaatatta
    13141 gagcaggcga aagaagaatt tttagctcct gatgaaaatg gtatacaggt atttgaatct
    13201 tttgattatg aaaaaatcta tgcgaagaaa ggaagaaaag ttgatcggct cagattcact
    13261 tttagtgaac cagaatcaaa cttgccatcc atttcaatgc ataattggtt agaagaagac
    13321 tgaaaagaag caggttgtaa ttttaataca acctgcttct tttgaaaaaa gtatgggtaa
    13381 cacttttgga caataaatgc aagaagtttt tttgtgacca aactttatat tagattcctg
    13441 tgattttgtg tgttagaaaa gccctgatag aaaagcaaat tcaaacactt tttaatatgt
    13501 atgggtaaca cttttggaca tgtcaataat aaatatattt tctttcgtct tttgcctaac
    13561 taaaggtaac acttttggac agtatagttt tgtaaactaa ttagatcggg tttaatgaga
    13621 tatatcttag catttatgta agaatgaagg taacattaat ggacatgtca actgtttgaa
    13681 caaaaaaata tagaatattt tgatctgatt tttcattttt ccaaacgtta aaaaatagtt
    13741 agttatttta ttaatagata gtcatcctta atgtttgaaa tagcagaaaa taagatattg
    13801 tttgataaat gttgttgtta taaggaaaac ttgaatttgt taattgattt atttatgtta
    13861 ttatgatact ataataacat aaatgtgtta cgcccgaacc tcattttaca aaaatgaagg
    13921 ggtgagacaa tggatgctat taattggcat gaatttgtta actatatgga gaaactacta
    13981 gatgatctga aaagttttag cattgctgat gccgtaaaac atgggttgcc agttagtaca
    14041 acgatgaaaa tgcgagggtt gaaggttccg gatgaaatta tcaagctgag gactaaaaca
    14101 atcattgaaa ctgcaaaaat tgttgacagt atgaaccttg atttgaaagg caaaaaaaca
    14161 acttatgaga aagactttgt acgtttttta aaaaatgtta tcggaaaata tctagggaaa
    14221 aagtctttta ctgaattgag agacgaagag attgtaccaa ctccaatggt tagcaaaatt
    14281 cgcaaaaaca aagccgaggg aaattactat cttggcacaa tagcaaaaat cgttgagtat
    14341 ttggaaaata aagagcaaaa gaaaggaacg aagaaaggaa gatagttcgt gtgataaata
    14401 tgaataggga agaatgtacc gaaatgataa aaaaacccga acctagaatt accgaaaaac
    14461 tgactgattg cttgctcttt tacgaaaggg ggcaggcaaa ctaatggaaa aagatgtcaa
    14521 ttcagcatcc actaaagatc aatacaatat cattggagga ttacttggtg ataaggataa
    14581 gagaacacgt catggattac gcattatgct tgcgacattt ctaggggtgt ttcttttatt
    14641 aacaggcttg ggtagctaca tttatcaatt aggaaactat aattattatc ttgtcaacaa
    14701 tacaacacca atcggctcat cattgacgtt tgctcgatca ggagcagaga tcactatctc
    14761 agatgtttgg acagataaaa ctagagatgt aacggtggtc aaacttggtt actcaggaaa
    14821 cgcaagaaaa ttgctatcta cacaaggtaa aaattataac ttgtatatgg caacaaaaga
    14881 aaaagatcgt cctaagaagc ttgaaatgag ttatgggatg ttaagtaccg atggtgatgc
    14941 tttcttattc ctaaaaggta aattagatga aagagcttat caagttttta ttgctaacca
    15001 agtatcacta atttcaggtg attatacagc tgatgatgat accaaagtca atgtgaatga
    15061 atcagattca gtcaccaagg cactttctca gtattctatg aatgatgttg ataatgaagg
    15121 agtaatttct tttgggaaaa aagcaaaacc agttaatact cctgataata tcaatttcag
    15181 aataaatcca tactcagata caactaacgt atatcaagga agcttcctta ccaaagatgg
    15241 cgatattgat tactcaaaag ttgttgctgt gacaagtaag aataatgttg taaataagct
    15301 agaagaccag ttaaatgctt caaatactaa catcaagaaa atcgaagcca caaaagctga
    15361 gtatcttgaa cgtttacaac aaaatcctga cgataaagat tcgcaagaaa gtattcgtca
    15421 actagacagt cgaatggaga ccgaaattaa aacaatcaat gatacacaaa aattgattga
    15481 tcagtacaaa aatgctgact ttaacaaaga ttcttttgga gatatgaaga caacatttaa
    15541 gtacctaacc ctgactgact agaaacaaat tgttcttatt ttagaggaag tgaacacaaa
    15601 cagatggaaa atagtaccga gttctttaaa aatattcaaa ccgaattcaa tcatgctctc
    15661 acactaatga aaccaccgaa acataagtta gtggggcgtg atgacgaact ccatgagttg
    15721 tcactgatct taaatagacc ggaaacacca caagctatct tgttaggtga agcaggaaca
    15781 ggtaaaacag cactggcaag tgaatgggct aaaagacagc gacaagaggg gaagaaagta
    15841 caagtatata aattatcaat cggacaattg cgagttggag gagatgacgt cctccaaaca
    15901 cgtttggaaa ctataattcc aagattgaag gaatacgaac gaattttaaa atccgaggac
    15961 aaagataatg aatttgtcct ctttatagat gaatttcata aagttgtcag ttcatttggg
    16021 agcggtaata aaattggggg agattcgctg aaggaacctt tagcaaatga atcacttcag
    16081 ttgataaccg ctacaactag aaaagaatat gaaaactata tcaaacgaga tgatgcttta
    16141 ggtagacgac tacaaccgtt agaactcaac gaattaaaaa gtgatgtcgt tgtcgatata
    16201 ctaagacaat ggttgaatac atcatctgtc aaagatgatc ctgaagcttc cttgaaatta
    16261 tccaaaaaga ttcctgatga attgcttgaa gaaatcgtac aagcaaacaa gctttatcgt
    16321 gaggatttat ccgaaccggc taaatcaatt gccgtaatgg aagatttgat tgcgaaggat
    16381 cgtgtagatg gcaatgcgta taatcgagaa agcctgttac aaatatttgg aaaatataat
    16441 attcaactag attctgattt tgatatagca aaattggaag aggagctaaa gtccattaaa
    16501 gggcaaccag tagcggtata tacggtcacg atgttgttta aacgaatgaa acttggattt
    16561 gatcgtttta aagggcgaaa gcaaccaaaa gcaacggctt tgtttacagg atcaacaggg
    16621 gtcggtaaaa ctgcgatggc taaagctgta gcaagagggc tatacggtga tgaaaataaa
    16681 gtccttttag taaatatgcc agactataaa actaaagatg atgctatgcg gtttagaaag
    16741 cttatcggaa cacatgtccg gcatgatcca tcagcaatca ttgtttgtga tgaatatgaa
    16801 aaagcaggcg tagaaacact tgatgccttt ttatctattc tagatgaagg aagaatcagt
    16861 tttactgaaa gaggatggga tgatcgagaa gttaatgata ccgtctcact ttcaaatgcg
    16921 attttatttg cgacaacgaa cgcaggggct gagatgtacg attcgatgaa ccgatacagc
    16981 tcactatctc gtgttgctaa tcaggaaaat tcaaatgagt acagcactga gcttaaaaga
    17041 gagtatcgaa aggtagcatt agagattaaa caagctctaa ttggtgaagg tctaaaaccc
    17101 gaagtcatca accgatttgg acggattgtt ccattttggg ctttatcgga acaaactctt
    17161 ttggaaattg cacacaatga aatattgaaa agtgctgaat tggtaagaaa acacttaaac
    17221 gtagacttac gccttccacc acagaaaaaa catttctatg gtcaagaatt ttatgcagat
    17281 gatctctcca tgcacttagt ttttgataga gcttcacaag aagattctaa atcagggggt
    17341 gcaagaaata tcttgcatct ggtcgaatca gaatttgaag aagcaattac tgaagcaata
    17401 attacctatc ctaacgccaa aatatttgac gttaaattga gcaaagcagg agggtttgaa
    17461 gggaaaggcg atacggatgc agaaattatc gctaaacctt ccatcgctga aagtaaagaa
    17521 aacaagtttg tgttttcggt tggaggggtg tagctatgaa atttaaaaag tctttacttc
    17581 aaaatcgtaa aattaagcga tgggttgtaa gaggtttagt tatcgtgggg gcacttgcag
    17641 ttactttagg cgctccattt ggaatgaatg atccaacgtc tgatgatcaa ggaaataaac
    17701 aagaaacagt tgcaaatacg aatgtggctt atgctgaaag taaaccggca gaaaaagggg
    17761 tatggacact atatgctcgt atcctgatgg gagataaaga ggtcaatgat agtgccacta
    17821 aaactggtca aatgaattta cttggtcaag gaggtattag tgctgacttt ccttattctg
    17881 atatttccaa acaaggtaat gcaattgccg gtggtaacgc aggtacgcaa ttagcatcaa
    17941 ccttagcgac ttataattac tatgggtata tcgaaacagt ttcaggaaat gcgattgcaa
    18001 gtcaggcatc ctcttttatt ggtggtatcg gtagaacgct tggcagtttt atcggatcaa
    18061 ttagcttgat actttctaat attgctgaat ccatcaatga actccttgga aaatttttca
    18121 tgagtatgaa tatattttca cttatgggtt ggggtaaagg tggatcggat gtttctaatc
    18181 cggtagctaa ggcgttaact agcttactta ataatttggg attaaacaat caattattta
    18241 aagcgatagc aagcttatct atgctctttt ttacagcaat actaggctat caaggaatga
    18301 aactgttgtc gaaagagggt gttaactcaa agggattatc accagtactt gaaaaatgga
    18361 ttgttcgtat ttttgtattg tttgtttttc taccagttgc aggatcgtta ttgggagttt
    18421 atatcaatgg tattcagtca gcaaaagaag atggaaaatt accaacaaat gttgttggtg
    18481 attacatcat taatacaaga ctttgggctt ctactcaaaa tcttgctcca tcatccgata
    18541 ctggtgggaa tgtgccaaac ggaaaaccaa catctgaaat taaatttgtt gacactgatt
    18601 atgaaccatc taaaaaatca gaaatgatca gaatgatcaa tactagcagt tacgctagac
    18661 aaaataatga tctagattcc aattcagtcg gcatggcatt gttaaaagaa tggtcaagta
    18721 atgatacgtt taatgtcaat acttatgccg gtgatgtgaa tgtagctgaa aatgatgctt
    18781 atatgggaag agcgcctgct gtttggacag gctataattt aggggatgga aaagaaggaa
    18841 atgcaattaa gaaacctacc aatttaaatg gttatatttg gtcagctaat caaaacgtta
    18901 cagacgacaa tcgcaagcct gatggaaaag gaacaacgaa taactttgat gctactcaac
    18961 cttggggtgt tgctaacaat gcaacgttta gcacacagtc ggtagcgttg atgctccaat
    19021 cagcactgga tacatcaggg gctaagtttt atgcgtataa tatcgctcca tcaggaattc
    19081 aaggtagtgc taagaatatg tcaacagtaa agacagaatg gcgtacagct tctttagttg
    19141 gtcatggagc tatgggtaaa ttcggctcat ggttagcgat gaacgctgaa tcaatcgtat
    19201 tagcagtgct ttatctagct tgtgcttggg cgatgtttaa cgttaatatt gtaaaagcct
    19261 tcaaacgtga gtttgtgcga gtttgggaag tagtcttaac agggtctctt gccgcaggag
    19321 caggggttat ggcaatctca ttaggagtcg taaccacatc tcttatcgga ttacaattac
    19381 ctatttttct gatcaccttt gttcgtgcat ttggagatac ggctgtagga ttcatcccta
    19441 acacattact tggtgatggt gtagcaaata ttgtacgatc cgctatggtc ttaggcgtag
    19501 gataccttct agtctttaag aaaggtgaaa aggttaataa taatttgatt aatatgctta
    19561 ttggattacc acttgaagta gcgtttggtt ttgacgaacg tgctaagtta ttatttggca
    19621 atagaaatga tgctgttcga gttgtggatg gcgtttctaa agcaatcaaa aaaagccaag
    19681 gggctaaaaa tccttattat gatggtggca gaggatcagt aaaagatatg gtcgcaggag
    19741 gacttggagc agtcggagcg caaggaattg ctgatcgttt gaacaatatg ggagacagca
    19801 atgctgatgc taagacaatc gctgataaag ttgttcctga aacgcctgct tcagtaccat
    19861 ttaatggtgg cggagttggt ggaacaatca ataatacctc tttcaaagat ttagttcgtc
    19921 aagatcaatt acgtaataac tcgcaacaat atagcgatca tctaggacgg atggttgatg
    19981 aaaaaggaaa ctttgtcgat gaaaatggtg aagtattaaa agacagtaaa tttggtaaag
    20041 atgccaaagg aaactttatt gatgacaaag ggcgtttggt cgatgaagat ggaaatttga
    20101 tagatacaaa cggtaaacca ttggaagaca atgaagatgg aaacatcggt atggatagcc
    20161 aaggacgttt aattgatgac aaagggcgct tggtcgatga cgaaggaaac cttgttgatg
    20221 aaaacggacg taaattactt aacggtgatt ttgggcagga tgtaaatggt cgtctagttg
    20281 atgataaagg acgattagtt gatgaagacg gaaatctggt cgatgagttt ggtaagaaac
    20341 ttggaaaaca cagtaacggt tataacgtaa atggcgatac agtcgatgaa gatggaaaca
    20401 tcattgattc aagagatgct cttgtagcag atcgaaataa agaactcgaa caacaacagc
    20461 atacaccaat tgcggttgca atccctgatg atgaaagcga tgaagttatt ttagatcaag
    20521 cacatcaagg gttaagagaa gaagcaaagg ataaagttgt ttcagatcaa gcacaagaag
    20581 agctaaaaaa taaatcgaat ggtgaagatg tttcaaacca atatcatcaa acggctggaa
    20641 atgtacctgt tgaaggtcag tctaatgagc ttcacaacaa ctttgataat gttgctgatc
    20701 ggaatgatac agtcttaaaa gaaaaagaat cattaagaca agaaacagat aaagaccaat
    20761 caaaattgaa gaaaacaact attcctactc ctattggttc aacagttccg aaggtcaatc
    20821 aagctaacga ttctgaaaca aacactgggt taggaatggc gaaagacaat caatccatta
    20881 gagaacctaa aaagacgact gaaagtagca agtcgaacaa gtctaaatct acttcaaata
    20941 agacagggaa atctaaggaa ccatctaaag ctaaatcagc agtagaatat ctatctaaaa
    21001 ctggtaagaa cgtgtatact tcagcagata aagctttagc aaaagcgcca aaaggaagct
    21061 tagcaggaat gacctatgaa gctaagaacg aagctatcaa attaggtaaa ggaactgcta
    21121 aagttgccaa agtaactgct aaaggagcaa ctaaaactgg taaagcagtg aagaaatcta
    21181 cgatgtcggt gaaagattat attgcaaaat atagcgaaca aaaaccaacc gataaaaagt
    21241 cttaagaaga ataaaaagag ggagcattaa tatgctcctt cttttttgtt cttctcttca
    21301 aggggaatgt caagaaaaac ttaattgtct tcaaaaattt cttttttatt tggtagtaaa
    21361 tctatgaaat atttgctttt ttagttatcg gagaataaga gggcttatgc tagttagtta
    21421 aaatcaggta actagtcatt aaatgctgat aaataagcaa tttttacgaa aaaaaaagaa
    21481 aaaaatttga gggaaaatac ctttcaatct acaaaaattt atgttattat gataacataa
    21541 agatgtaaat atcggagcat cttttctgta ttccgatcat tgacaagtga acagagaaaa
    21601 gtttgcgatg atataattat cttgtgaaaa ataatcgaaa ggaaggattt ataatatgtt
    21661 tgattctatt aagaatttgg tttccggaat gacgccagaa atgaaaacgt tggttcaagc
    21721 tattctatat ttaatggcta cattttttgc attgaaacca ggattcactg ctatgaaaca
    21781 tttcggtgat gcaaaatggg gagaaggctt aaaatatgtt ggagctgttg ttgctatttt
    21841 tattatccct gtaattacaa ctgttatgtt gttaacgatg ggtactaaaa caggtaatga
    21901 cttaaaccaa aaagctaata tgatctcagc tcttattcct gtggttggta tttatctagt
    21961 tacaaagttt ccaaaagaag aacaattagg ttaaaaggta aattgagcaa atttggatga
    22021 tatgccgatt tgttcaattt actttttgct aaaaaactac actcgaagcg tagtttttga
    22081 agtgagggaa gacaatagat gtaagatgga cagagaaaag atgttggttc acgcaaacga
    22141 agtattgacg agcggtttta aaggtaccga tttggcgaag ataatgaata tgaacgtaaa
    22201 ccagttctat gattatcgaa acggcaataa aaagattgaa aaagccagac ttgaaacgct
    22261 catcaaattt gaaaaagcgt atctatacgt gttagacaaa cagaaaagaa ctattgaccg
    22321 aaaaaaagga gttttacaat aatggcaaaa ttcaaagata ttaccgaatc tattaattat
    22381 gtagcagaaa cagttcccgt agttgtactc tctttgaagc cacaattact cgaagtgtac
    22441 caaaaagaag aaaaagaagc gaaggcaaaa aaagctaaag caaaggtatg gaaagaattc
    22501 gatgcgttgc tgaccaaaga tttaccaaag aagaattacg tggtgattga ggacgtacaa
    22561 aagctcagca gtgaggaatt tccggatgag gaagatgcga ttctagattc cgaaaagtac
    22621 gttgttttat taaaatcaag tctgaattat gttgttgatt taccggaaaa attcaaagaa
    22681 aagctattag ctggtgtccg ctttatggat agtaatggtc aattattagt tattcctgat
    22741 gatcctaata tgtttgaaag agaagttgaa gaagctacag acttctacag tgcagtagat
    22801 caattagagg tagctactaa aggcttagaa agaattgctg agaccttcaa ctcttctgat
    22861 gcggttgaat ttgaagctgt agcagaagcc gaaacagaag ccgtaccaga tgaagaagaa
    22921 gctctttttg aggataatga cgaagcaact gaagcaggaa accaagaagc aagcatagaa
    22981 gaaacacaaa cagaaaccta ccaacaacca aaaattgatg aaaaacccga atcccagagt
    23041 gataaagaaa attatgttta tgaagctgaa aaaatcgaat ctgaaagtga tgtaccgaaa
    23101 aatttagatg ctgatttgtt agaaaaagat tttgaacaga tcatagccaa taaatttcaa
    23161 cctgtagttt tagatgaggt tagtgatcct gttgatttga acgaagagat gcgatccatt
    23221 gcagagttaa aaccattgct gtttttagct aaagagagca tgaacgctcg tatctctatt
    23281 gctaataata aaatcaacag tgaattaaat aaaacgaaag agcaattgct actcaaagga
    23341 aagcaaatgt tagcggatga gcttttgcgg atagaggaag caacatcact aagtggtcaa
    23401 aatcagttta caaatacgct atcggtcgct aaagaaagct acgaagcaga agcatctaaa
    23461 attgatgatt tagtgatgga aaaatccagt atcattcgta aagattatga tatggcgaaa
    23521 caggcttatt tggaagcaga actaaagaaa ctagagcaac ggtacgatgc tgaacatctg
    23581 ccagaagtta aacaacaaga agatgaattt agaaaagcaa ctgaagaaag tcttgatcaa
    23641 caataccaag aagcaattga atctattaaa aacgatgctt tgaaacaaaa tcaagaagca
    23701 aaagaagttg tggtggaacg gatcatcaat tcattgaaac cggaaattga aaaatcttta
    23761 acagaagtgc aagaaaaaac gttagagatt gtcgaaaaaa caaaggcaga aaatgaagct
    23821 gagttccacg atacaaaaga gaaaacaaca gatgtggttg tcaaatattt tgcgaacaaa
    23881 gaagaagttg aaaagctagt agctaaagat acgaatgagt tagaatccaa acttgttgca
    23941 cagcaaaaca ttattgaaga ttataaaaat cgagtaaaag agttcaagga tttagcagat
    24001 ggctataaat taaatagcca aaaattgact gaacaaagtg aagctttacg agaagattta
    24061 tctcgtgcaa gaaacgacct atcacaaatg gcggaaaaaa caaagtcact agtagttact
    24121 acagaaaatc aaactgagtc taaacgagat tttacaagca aaaagatggc gactatcatc
    24181 gctgtatcag caatggcttg tggaacgatt ttgggctcat cctacttcat tagtcataat
    24241 caccaagaag cccaagctca aacagaaacc tcaatttcaa gagtggaaaa ttcactagga
    24301 gcaaatacag cttctacttc aacaacagac aacaactatg aagcaacacc aacgacagaa
    24361 tttaaagtcg gagaagatgt tgtcatcagt attgatggga aaactactaa ggctgaagta
    24421 ctttccattg acggtgataa ggcagttgtg aaagctccag atgggaatca atacaaaata
    24481 caagctcact taactgaaaa gaattaagga gggctaaaat gcgagaagaa aatattgttt
    24541 atccagtaat tgaaaatcaa gcaaatacaa aatcttctca acttcttcaa gaagtgcaag
    24601 tcgtttatcc ggttaatgaa ctaccacaaa cgaatgaaac agtgagcaag tcaatatcat
    24661 taattggctt gcttattgtt gcaacagcgc taactgttgg tgtttatcgt aagctgaaag
    24721 tgaaaggaag tatttctgat ggcagataac tcaaactatg gatttaaaca taatttgcat
    24781 caaaaacctt ctgaaacaat agtcagagtt gattggcttg aaaaacatgt caacagcacc
    24841 tattctgtta cagcaaaaag actaattgtt tcagctattg ttgttgcagt tgttgttctt
    24901 ggttcaatcg tttatttggt ttccgatacg attaaattga gatttatttt tattccaacg
    24961 ctattgatga taattggttt tcttatactg attagtcagt atatgtttat tgatccatct
    25021 agcggatcac tgatctcagg ctctattaga ctgtttaaat cagtagttaa cacagcaaga
    25081 gtaacgatgg ggaaaaagaa accatttcga ggaacggaga ttttgaaagt tagacaagat
    25141 ggaacgatta tgtatcgaga tggtagtgta gcactaatgt ttaatttgga tggtgctacc
    25201 tcgttaaccg ccttcccaga agaaatcata gcgcaagagg gcaaatcaat tcaataccaa
    25261 aatgcaaggg atcgttcctt ggctgaaatc aaaattactt catcacaacc tcagaatacg
    25321 gaacgtcaaa tacggaacat gaaagtacaa aaaagaaatg caaagagcaa caaagctgtg
    25381 tttgacatag tagatcaaca agagaggttt gtatctgaat atattgatgg ggtcaaaact
    25441 acggtgatcc aatatcttat tttgaagtcg caatctcaga tggtattgga tgaaggcgta
    25501 gaacgtttag aaaattacac gagtagaggg ctttactata gcgttactca gttgtcagct
    25561 aaacaaacca aagaaatatt atcagaaatt tatgcactga aataatagag gtgagaaatt
    25621 taatggaact aatgagtaga tcgaagctac ttaatttcag aaaaaagaaa cacaaaaaag
    25681 agcaaaatgc tgatagttct aaagcggtga ataatactta tgtcagtgat ttaacatcat
    25741 tggttggtta tcaatttaca ccatcttaca ttaggacagg taatcggtgg ggaacgattg
    25801 ttaaattagt gaatacgtat ggaatgaaca gaaattatga atttggatgg atggttaaag
    25861 ctattcctga agtgaaggtt gaaggagtaa aagcttactt aatcgaagcg gataagccag
    25921 tttcgcaaaa agatcagcaa gaaatcatgc acgaaaatgt cggtggatca acgaacagtt
    25981 atgaaaataa cttgaacgat aaaaattcag atgcagaaat caataaaact gttatgcgaa
    26041 tcattgattt gaatacagca tccctgcttg acagtacggc aaacaaaatt attgattgga
    26101 agctagagat ccttttagtt tccgattctc ctgataaaat cagcgaacag ttgattaaac
    26161 tgcaacgcct atatgatgaa aagatgtatg gattaaaact catgtctttt ggtggcgatc
    26221 aacgtgatct gtttgataga cttttaagcg aaccggtggg aagtgtttac gaatacacat
    26281 ctatgagttc tgattttgca ggaaatgatc atgctattcg taaaggctta gatgatgcag
    26341 atggatgggc gatcggtacg atgtctacaa gctacgcttc aggtgtagcg tttatggcaa
    26401 tggatcgttc ttttaagggt aaagtcttag tagcatccca caaagatgca acaatcaaag
    26461 gctatagcga agaaatctca gcatcatcac tttgggggca attgattgct aataacgcaa
    26521 tggcaaatca taaacggacg tttcacatcg tattgaataa atttgactac tttggtgatc
    26581 cgacagggga aacatttgtt gctaagccat ctttaaatag tgtgatagag aagattaatc
    26641 tagctgaaga aggacttaat tctttagagc tttttggtga tcgaaaggat attggagatt
    26701 tatatagacg taatcttgat aaactaactc agattttcta tctgttagcg gacagagaat
    26761 taaatcctgc aacaagagta ttgctgaaga aagagttggg gaacttttat attagtcaga
    26821 agctttggga tattaactat gaagagcggt cgaaactgtt agtaaacagc agtgatacaa
    26881 tgccggttct tggggatttc atcagctatt taacaaatgc tgagacaaaa gcgaaaaaat
    26941 ccggtacaga aaaagaaatt gatcggatta ttgtattaaa agatacattg cgaacagcat
    27001 tggatagctt ctctaagatg ttcaatcaga gaactacatt gaaagaaatt ggcaagagcg
    27061 acaaattgca gatttactac aatttgagcg atttaagaac agaaatcaat gtcatggaag
    27121 cccaattttt aaataccttt gacttcatca cgtcacaagc taaaaaaggc gatatcgtta
    27181 tgatccatgg gtttgataga ttatcagttg aaaccgttgg attaattaaa aagcgactaa
    27241 caatgcttga agaagatgga gtccggcttg cgtttctctt tgatactatc ggatcaggag
    27301 aagataaaga cggtatcgaa acagctgata ttttcaatac tgatggaaaa atttatcaaa
    27361 gttttgaaag tgattttaac tacaccatca tcgggaaaat gaccagtgaa gaattgatga
    27421 agtatgaaaa gaaggttgct cctgcaagaa aaggagaaga tgatcaaaaa ctatcagtgg
    27481 atttgagaca gtatttgaca tcaggtcgaa gcaataaatt tcaaatcaga agaccagtcg
    27541 atttgacgaa caattttgtt attggagagt ttattattta agttctattc ttgtttttga
    27601 atatttatgg ctaagaaata acatgcttat ataggactaa gtaaacagtt ttagagaacg
    27661 tgatacctat catgaaacga gagctatagt aatttcacaa agtgaaaact tactgagaga
    27721 aagaattata gtggaggtaa aataatgaaa ggtggttgaa gcatgaataa tttaccagaa
    27781 aagaatcgtg tatttagatt gaagggtgat ctcagccaat ttaaattaga tgaaaatgga
    27841 gaattttttg tttggatgag acatgaacat tgttggtgta atccttttga gttaagaaaa
    27901 gaaaacgaaa ttagaaccaa aattgaaaat ggagagtggg attacctctt caggtggtca
    27961 gacgaatctt ttatagcaaa caacatggat catgcgtttg tttcatttct ggataataca
    28021 tggggtactt ggtacgattg ttacctaaaa aaattgggat ttcaaaatat tgatattgat
    28081 gctattgagt gtcttaaaga agtcgataat aagtatgaag aagaaccata ttatctctta
    28141 caacaaaaat tagccaatga ttcagccttt caagtagaag tttgggaaaa cgaagatgga
    28201 acctatgaag gtctagcgca agaaattcca ttatcagaaa agaagtgttc gatttgaaaa
    28261 aagtatatca acatttttta tgtattagtt atatcacctt atttagcttt atttttctat
    28321 ttggtgtatc cgttattgtc ggaacaattt tcatttggct taccgatgaa gatatgtcat
    28381 tgaagtggtt tatgtgtcta ctatcgtgca ttatgttagt tcttttatgt ttagaagttc
    28441 gtgaattttt gccttctcat tggcaagaaa aaaggaaaga gcttagagaa gaaatcgaaa
    28501 taaaaacgag cgactggatg gatcatactt ggttaccatt gaaaaaaaat attaagcaaa
    28561 aagaattttg ggttctacaa ttatgggcat taggaaagtt ttgcagttat gtggctctcc
    28621 ttattttcga cctaatcttt tactctatag ggatatttgg aacggcttat tacttattaa
    28681 ctgatcacaa taggcttgca gtgtcagaca ttttcacagt gttaatgaca ttgatttttg
    28741 tcattcaatt gtctattttt agtcaattac ttatccgatt tatcagacaa aaaataacaa
    28801 tagacaaact ttttagaagt ttagtcgatt tacttattat aagtgtcatt ctaatgaccc
    28861 taacagaaag gatcgaacaa tcaggaaaaa cagtagaggg attgaaggaa tttttgacta
    28921 tgttcattca gtttgtaaat gggcatatgt atttatttgt gtctggcatt attctttcaa
    28981 tgatcggata tgtaactacg aaacttatta aacgctcaat tgaaaaagaa atagagattg
    29041 acctgattcc gacactttct ggctatgact attatgtcaa ttatgggaag tttgaggagt
    29101 tgcttcatac gaatattgtt cgcacaagta ttcgagaatt tacaaacaag gaaataaaag
    29161 attccattca tggagagcca acaaggaagt tcattgaccg tcaaaagaag gtctacaatt
    29221 tttatgaagt ggaagcgatc ctacgatatg gtatcggaaa attgtggcta gaaggaagaa
    29281 atatccgtca aaacaaacca tacgtttttt ggaaaagtgg agttttagaa caatttccta
    29341 ggagaaatag ataaaataaa aggagcaaat ggttatgaaa caatatttaa ataaatggaa
    29401 agtgatagag gggtcattag tagcacaaag aataaaggga ttacctgatt gcttagagaa
    29461 ggatcatttg tttcaaatac gagaaatgtt aaaaaaagaa cagtttgatc cagaccaatt
    29521 tttagtagtc gagtatccaa ctattggggt gtactgttgt aaccatatca atgatggaaa
    29581 atattttatt attcaggaat atgaaggaca gttaactcct ttctatacta catgggaaat
    29641 gagtgaggat gggatcaata attttccatg tgaaagcatt gaagagtcaa tatctcaaac
    29701 cgaatgttaa ttgattataa ctataaaaaa ggattgaaca ttatgttcaa ttcttttttc
    29761 aataaaatgt tttccggcat ttcattattt ggtgtaaatt cgattttcaa cacagatgga
    29821 aaaagctatc aaagtttaat agtgattcta actacttcat tatcgggaga atgaccagtg
    29881 aagaattgat gaagtatgaa aagagggttg ctcctgcaag aaaagcagaa gatgaacaaa
    29941 aggtatcagt ggatttgagg cagaatttga catcaggtca aagcaataaa tttcaagtca
    30001 gaagaccagt ttatttgacg accaattttg tgattgaccc tcaaactttt ggatgctaaa
    30061 atgtgacatg agatgatttg tgtgcattat ggcacaaaaa ctacttcctg actgcgacga
    30121 aaggaagtag ttttttcatg acctagaata agaaaggcag tgaatgaatg gatacagcta
    30181 tattgtatat taatatactt ccatctatat cctttattat tactcttaca tttttcgtac
    30241 gtaaaaaaat tttttttaca gagaagaagc ttgtatgctt tttggtgaaa tgtggagtag
    30301 tatttctttt ttcttggtta tttctgattt tatcaactct aagttttcta attatattat
    30361 ttgcgactgt gtgtctttta gactttggtg taatagcagt agcagtaatg tggttttggt
    30421 taactagaaa acctaaaaaa aagaaaaatg gtttggagaa taaacgatta ttcagattaa
    30481 tggaaaatca ttgaagacat aggcatattg gacatattaa gagaaaaaaa ctaacaattt
    30541 cttgattttt tgaaaaagag tatatatatc aagtcaaaaa cataatgatt tgattttgtt
    30601 atattgaaat agatattaag aaaaagcatt ccttgttaaa acgcaaggga tgctttttat
    30661 cttcacttaa tctgtttaat ataatctaac aacttttctt cggaattaat tttttcacct
    30721 aggtattgtt cagacttagt aataagattc aatttaagat catttaatat ttctggatac
    30781 gtatcacttt tcgattcagc taattcatac agttttttta gttccttatc ttttaactga
    30841 aacttctgat ccatagtgac agcatttgga tatagaagtc cattataatg tgtgcgtaaa
    30901 tccatgtgga atttttgttt ataaaagtct agcagattag aaataaaaga agaaaaataa
    30961 ccgttatggt aaaactgatt atttctattt aagttataca acaatttatt aaatttatcc
    31021 tgatttaatt tgtcgtaaat ccatggcaat acttccatgt ccttatctga gaatttaaat
    31081 gcaggagaat cggtcagatg ctcaatcata aaatctaaga acatctcttt ttcgccaaaa
    31141 tatagatatt gattatatat cgtttctaag gtagaagttg ctagagaaga gactctcatg
    31201 ttttgctgaa gtattggatc aagtagtcta tttaagtgtt cttgtaattc tttcttggtg
    31261 tttcctagaa ctgcaagtga acgtagacgg tagtaatctt ctatatgtgt tgttattggc
    31321 tgttttggtt caaaatcctt tattgatatt tttaagtttt gaattatttc ttctgaaaaa
    31381 tcacgctgta attctggatg actagctata aaggtaagta aaaagaagcc ttttgtataa
    31441 gttatctgtt gattttctcc aagtgattta ttaatttcct ctctcgattc agctgtgaac
    31501 ctgtagtttg agatttcttt ttttagaatt tttaaataaa attctttgct atcaaaaatc
    31561 agggcatcta gtagtctgaa agtactcact ctatctctat ctacttcttc attcccataa
    31621 ggtaatttaa aaacaaactt aaaggctgtt ttacaaaggt tttctttggc tttctcactt
    31681 agttttttca gatagctatt ttttagtgca gagtgaaatt cttcaggtgt aacagacata
    31741 gaatgtattc gacttgcata ttgtatgatt tcgttcgtta ctttttttcc taatattgga
    31801 ttttttagaa atacaatttc ataggatttc cgtatcacat cctgacaagt ttcctttgtt
    31861 atttctctta attcccaagt gtcaccattg taagtaacta ctggatgagc tgaataattt
    31921 ctttgatcct taatatattt taaatcctca tattcgtagc tatcaattag ctcagtcgaa
    31981 ttataagttt tttctagtag ctccatttcc catcttgggg agtttggatc tttttttctt
    32041 aatttagcta tttcttctaa aattttctta gaagtatcat cctcgtatat atttgctaaa
    32101 tcagataatt tatcaattaa gtctaaaaca agcgcactgt aattgacagc tatcgctgaa
    32161 cgataatttc cctgataaaa actacttctg acttcttcta ataaaggaat aattctagga
    32221 tttttaactt tgtttatttc atcatctaat ataaacatat aactctcctt tttttgttga
    32281 tatgacaagt ttaccacaaa aaataaatta aaaaacgaga catatttatg ttattatggt
    32341 atcataataa cataaatata tggaatgaga tgatgaaaaa tgggcttgaa acaatcagtt
    32401 tacatctggt tatatcctga taatcccatg tcaataatgg ctgatatttt tgtaggtagc
    32461 attttattgt gtttactgta tctaattttc ttccacaatt taatcgggta catgatcctc
    32521 gattggaaag ggatgttcga tatagaaaga aaaccattta ataataagca aacttatacc
    32581 acctttgcag gtggagattt ggaagaaaaa gaagttgatg tgacacatga aattggatta
    32641 gctttatcag gaattcaaga tgctgttgca ttaggatcaa tgataacgga taccggatat
    32701 aacgcctatg aagtatttta tctcatgtat tttatatggc gagatagtca agatattatc
    32761 aacggtcgtg ctgaaaaaac aatcatttca aatactgaaa tttctttctg tatgggtgaa
    32821 ggggaaatga ttgtatataa agatggatca gcaaacatta aaaccgcctt tggtgatatt
    32881 gaaacaagta ttaaagagct tagggagtat gtacagaatc cctataattt tcaatactta
    32941 gcaggaagaa taaatttagt ttaggagtaa gaatatgaaa aaaattattg atcagccaac
    33001 aaatcgctta atagtcgaag gcgttatttt cgtaacaatg tatttcactg tgggaaatgg
    33061 tatttcaaat acaatcattc aaaaagaccc acaatacttg ttatttagtc tttatgcttg
    33121 gattgtgcag atgctttggg tgtctttatt aatgctgttg ttttattgga tagtacgggt
    33181 tattctttta gtgttaaaca aagcaaaaaa gaaaaaggat aggtgagtaa aaatgaaagc
    33241 aacaaaatta aaacttgtac tattttcaac agcagtatta ctaactttat cagcatgtgg
    33301 tacatcaaag agcgctgata ataccaaaga cacaaaatct agcagtacag tggtgactga
    33361 aagcagttca gcgcagacat ctacaactat gtcttcaatg actgagaaca atgctgaaaa
    33421 atttcaaaag tataaggacg taaatcaagg taaaaagccg gaagaagttt ataacgagtt
    33481 tatctcttca gtaaaaaatg atgaaagtta tgggaatgat ccattacaaa ataaaaatct
    33541 gactattgtt ctttacaaac ctgattgtcc tgattgccaa aaagcagaat ccaaaattat
    33601 gcaagaaata caagaaggat ttagttatgc tccaacatta atgcacgata ttaccatcgg
    33661 caaacctgct tacgaatatc atgcagttgc ggtagatata acggatggcg tacctgaatg
    33721 ggtgcaaaat atccctggtc tggctgatga gaacaaccaa tatcacacgc caacactagc
    33781 agtagtaaca ccaaagaaaa ttgatggaac actatactgg gatttaatgg gaatgacaac
    33841 aaatacatcc gatgaaatga ttgaaagcac cagtaactac tatatggatt tgggagccta
    33901 taaatcatac caacagtctg aacctgttat ggatgatcaa tctactatta agtagttttt
    33961 agggcgtaag ccctattttt ttaaaattat gcgataacaa attaatgatt tctgaaacaa
    34021 acgttcttac tcaactactc gaaacacaca agctaattaa ctagattata aaggagaatg
    34081 cgtaatgaaa gaaatcagtg caagtgaagc ccatatttct caaaagaatc aggttggtat
    34141 atataaggtg cttcatggtg aagggattta taaaatacag ttacttactg gttacaataa
    34201 cggtgcaaat gggaagtggt taaaggcaac aagtattcgt gaacttagaa gtgaagtaga
    34261 aaaaattagg cttggtctca caagtgaaga aatagctaaa ctgaagggaa ataattcttt
    34321 tgtaattgaa aaagaaaagg aaaaacatct actttatcgt gagctgaaaa ttgaagaata
    34381 ctatgaaatt gatttacctg aaaaattaag aattattgat caacgttcag aagaaaaatg
    34441 gaaaactgaa atatatccaa gcttaaatga ctacaagaca tcaggaaagc ccatgtataa
    34501 ctacacaggc tttttaacct acacacaata caaatatgcc tttcgcaaat taaaaggcat
    34561 taaacaagct gaaattgccc tgtatgagat gaaaaaagtg gatagattga aattgattca
    34621 agagttagtg caaaatacat ggaatcaagc gattgtcgag ctagaaaaag aaaatgggaa
    34681 aattttaact aataaatatc tgatcgtaaa tgaaattgaa gaattaattg gtttattttc
    34741 atgtgaaaaa ggtgaagtct tcttgaagtc atcaccaacc tattcaattt tggacagtcc
    34801 gtatcagttt atacaggcaa ggagatgagt tagatgtcta gcttgaaaga tgactatatc
    34861 caagcaaaac aagagtatga aaaaatacag atgttgaaat ctgagaaagt cgaattattt
    34921 ttaacacaaa aattagcaga ggatcatatt gctaacttag atgctaaaac tttagaggaa
    34981 tatgatcggc agtttaatca gatacatcac aatatcattt tgcttgttga gcaggcaaag
    35041 cgaaggtttg aaaaagcgga atatgatcta ttagatcaag gaattgtatg cttggataag
    35101 ggattgcgaa gatattatgg tgcagagtta aaaaagcaaa atgtagatag aaatgcacta
    35161 aaacatgaaa tcttagaatt gataatgcaa cgaatttgaa gggatagaaa gcaaatgtca
    35221 caaaacatta gtgctgtaaa acaattaata gaagaagatt tagagaccac agttcagaga
    35281 ttagcggaac gaatccattt tgcaaattat caaaccatct ctaactggtc aagcaggaac
    35341 agaaatccgg aagaaattcc aatgaaattt ttttatcgaa tcggaaaaga atatggtgtt
    35401 gatccgataa aaattttcga gaagaccatg atttattact atcatggaac acctaacgaa
    35461 gtgttagaac atcttttgga agaggcagaa gaaaaatcat caatattaga gctatcgcaa
    35521 aatgacaaag ttattcaagt gaaatgcgtt gatccaacag gaaagattat tgtcggtttt
    35581 gatattgaaa gaaaatccaa aatagatttt attactcaat taaaaaagat aaataattta
    35641 gatattctaa cgcttagacc agatcatgaa cagttgttta tgagttttaa aaaacaattg
    35701 aaagaaatac aaaaaagata taacaaggtg tttcctaatg cgtgaaaagc tcaaagaaat
    35761 cagagttttt tggataatta acaaagaatt tatcatctta tatactcttg gatttctcag
    35821 catgatcttg ttttggtggt tatatttaaa aaagtaattg gagagggtca agaggatttt
    35881 tatcaagata aggatgtgga aactgcatgt ggaataatag attaaaaaca ggattgttat
    35941 taatagttat ttcctgcgct atgatgattg gtatgaggat acaaagggaa caatcctatt
    36001 ttgaagtttc tgctaacaac gtaatagaaa aatgctatta tggtcaacat tattggagtg
    36061 aggaagtcag agaaaatata gatcgtgaat atgttcaaag aattgtttgg gatgcatatt
    36121 ctatcaaaga ttatcctaaa agtttaacga gtagattatt ttacagcgaa aaagataatc
    36181 aaaaactctc agatttgatg atgaaaaaag taaggaaact tgcacaaagc tatttggaag
    36241 aaaaagcagg agcaataaaa gataaggaag aaatggagaa atttgctatt gaatgaaaaa
    36301 acggaattat ttttaaaaaa agtgaacttt cttgtagaaa aatatttttt aacaaagcac
    36361 aaaattatgt atctaataaa aggattgatc ggtggaatta ttttatggat acttactttc
    36421 ttttctttat ttggtggatt tactaattat aaaaagttag tagacgaaaa tgtgaagcaa
    36481 attagtgcat ctgaatcatt aagacatcaa gctgaagatt tagtaagtaa tccattattt
    36541 ataggaggta tggtagaagt gataataatt agcttcgtta ttggttattt aggtatgtgt
    36601 atcttccaga taatctttga tctaataaga ggaaaagtct ttcaaggatt taaatttgaa
    36661 aaaataaatt tacgttagag ataataggct atgagaggag aagaatagtg gaacaaacta
    36721 atcatattac tgaagaaact aggaaattca tttgtttaga atcgttttat tcggaaggta
    36781 ggtattgtaa caaaggtgaa acttatacgg catatcctat tgaaggggga tttaaattag
    36841 tttttgaaaa cggagacatg aattttacca ctgagttgtt tgagtgtgtt gttgaaacgt
    36901 ggtcagatgt gttgcttgaa gtcactaaat aatcaatgtt atctagtaga attaagcaac
    36961 taaaaaagaa agaaggaaga aaatatggcg tatgaaaatt tacaattagt agtagcagga
    37021 gttagtggtg atatatatct tgcaaaagca aaagatggaa ttatggacac gaactataga
    37081 agagttgcga cagatgatgt gttaagctca gcgacagaat ggtttcgaac taatgaagaa
    37141 tctgctgttc actttaaagg aattgatgga aacattcata gtttgttcta tacaaaagac
    37201 aaagaaaaag ccaaaaaaat tcttgatatt ttgaaggaaa gttagttaat taactaacga
    37261 tataagagaa ggcgagacca agtatttgct tggtctctat cattttaacc actagtcaat
    37321 taaataaata tcaaaaatga gtatggctaa ccacttgatc acgaacagca tcgctacaaa
    37381 tactgtatca gtatttgata gaatacatat tctattttaa aaaaagaaaa gaaatttatt
    37441 gatgatatac acaatagtgt gtataataaa gaggaagaag tgattagaac tttgagcaac
    37501 tcaatcattg ctttcgtagg agaataatag aacagttcct aagaagtccg ttgttcagta
    37561 aatttttgag taaaggagac gttatgagca aatacgaatt tttagacata aatgttggtt
    37621 ctgctttttt gattaatctt gatatgtttg aagcttgggc gcaatcatca ggatataatt
    37681 gggcatttag tgatgatatg atcgagtttt taagtcgaac gatgagttgg gaaagttata
    37741 aggtcaagca atttttagat gtcattgcaa aaccaatcta cacatctgct gatgatcatt
    37801 ggtcaggcag agagttggca acccttaaag aactagcaga gtacaacaaa aactacaata
    37861 ttccgtttca agtttcttac actacagatg atttttccgt tatttacgca ttaggtaagg
    37921 aaagtagata tttaatccct aataggtact tagagataaa gatgaatagc gattatacca
    37981 actatacgct aggtgagtta aaagctctta gacagagcga cagcgaggaa tttagcacgc
    38041 tcaaaaatga agtaagcaca gagaattttc gcatatcaga tattgaagaa ttaaaaaaac
    38101 agcaaaaaca gcaactagaa aagcaaaaaa aattaattga agacattgca tataaacgag
    38161 tagatgagct tgcagtacaa gaagctaaaa tagaaaaaat gcgacaagaa ctctatgaaa
    38221 aacagcaatc aatgttagct gaagcgaata aaatgcgctt tgaattggag aaaaaagtag
    38281 aagagttaaa tactaaaatt ttttatttgg aaactgaaat tgatgcgatt gaaggctatt
    38341 ttggtgaaag tacaactttt gttcagttgc gttcaggtca aaagagctta ccggaagatc
    38401 cagtggtgat gtttcaaaaa gtacggtatc tagatgaaga attaggaaga tatttcagta
    38461 tgcgagaagt tgaaggtaca gctgatacca tgctgacttt tgagcaggcg ctatcctcac
    38521 gagatgattt gtttgattta ttctcaccga acaaaaagtc aatctcaatg atacgtattt
    38581 ccaaatcagg atatggctac actaacggtc aaatggaaag tacaaacatg ctagaaaagt
    38641 ataaaaaata tcatggagaa actttagcaa ttttactgag aaacggtgat aacttatgga
    38701 tttgttggtt ggatgaaaat aagatcagtt tcaaagatga tttgttttac caaaacaaag
    38761 taacagagca ggcatctgaa accaaaaata tggtaaagga gatagattgg acacatactc
    38821 gtaatttaga agagcgattg aaagatgcta aaaagcagaa gagggctgtt agaggagagt
    38881 ttgctagtcg ttatattctt ttttcaatct tgcaaggtgt tctagataat ggaacgatga
    38941 tgaccttacc agaaaaagta aatgtgatcc aagcaattaa tcagaaaagc ccatatttta
    39001 ttgcaagcgt agcggatgga tggttagaag acacacgctt gccgtcattt agcgagttga
    39061 ttgataaata cagtttctat aaagaaacag gtgaagacag agtattagaa gcggaatatg
    39121 agttgaatcc cgataaattt gaaaatatga gagattatcc acacaaacaa aatgatgaca
    39181 tttatgtgtt atacaggtta cgtgggtggt cgcctacatc agcaaattat acttattaca
    39241 acagtgataa ccgttcaaat agtgagagtg gacgtgactt agcatattcg attgacttga
    39301 aagacggcat ttatcagatt aatttagtaa aacagggaaa attccaaaaa caaatgtttt
    39361 cccgaacgtt tgttggagtt gattctacta caggagaaaa tatctatgat tactattatg
    39421 aaagagaaac agagtactat attcgaggac aaaaagccta caacaaaagt gactattggg
    39481 gtgacaaggc gaagcgatta actgcaaatt ttagagtgta tgaatccgaa tttataaact
    39541 taacctttct taatagtgtt tttattgatt atgtcattac tacgaaacgt attggaagtt
    39601 attcaagtac ctacgcatcc ttagttccaa tgttaaactc gatgagccgt ttcttaaaag
    39661 aaagagaaga gaaagagcta cagtatatca aagaaattat gccagatttt gaaatgcacg
    39721 aatggcaaat tgctttatca gattggaaat tgacgaataa ggttcgtaga ataacacctt
    39781 ttcaagccaa gcgctttttg aaagctatga aatttgttca atagaaaaat ccaccagaca
    39841 agctgatgga aactaaccca attactaaca gttgtaattg gtattagctt acaagttaat
    39901 tatggtgttt agtcaatccc aaattgtgaa acggcaccaa taattggaaa ggaaaaatga
    39961 aatgtctgaa gatttacgag agctgaagtt acgaaagaag cagtatgatc agtatttttc
    40021 cggtttgttg aataaacata ttgaagaagg acttgatcat gattttggaa aagatgaata
    40081 ttgtttgtat tgcgagcgtt acaatgaaaa aatgtctgaa tatctacagc taaagaaaaa
    40141 gatacaaaaa ttagagaaaa aagtacatgc ttggaagtat aaagattcca tgtctggtta
    40201 tggtgaatct caaaataagc caagaaaaaa gaagcaagcg tatgttctaa agatggtaaa
    40261 tggggaagag ttaattgtat tagcttacag taaagaagag gttcgagaac tcgttgaaac
    40321 tcctgtcagg aaaaagatag aaacaataaa tgagatagac gacagccaat acaatagcat
    40381 ctatattgaa acaagtcatg gtggatataa gaaattagca actttcctta gaagttctaa
    40441 agttgggata atttctaaaa aagacataag tgctgttacc gatagttttt gtactttatc
    40501 tgttcctaaa gcatatttac aatacaacag taatagattt gaacgcttag agaaattctg
    40561 tagaccatat actgtattga aaactaaaaa attcaataaa actaaaagag tttcaatcaa
    40621 gttaccgact ggtcaaatct cgctaggcga aaaagattat ctgataaaag taggaaaaga
    40681 gttaataatc aaagtgccgg aacgcttatt taaagaaaat tttgagatac gtgaaacctt
    40741 ggtatggaaa gaagaataat agtttggaag acatagcagg gtataaggag gaattaaaat
    40801 ggcagtaaat agaaaattgc aggtattgat tacagacgac tttggcggag cagagtggtt
    40861 tgatgtgcag tctatagatt ttgaagaaga agtcgtagtt atagaaaatg tatacggcga
    40921 agaatactca tattcgcttg aaggagagaa tgttgaggat ttacggttga ttggtgagta
    40981 gaaaatagca gaaatatcaa aatggagatg aaatcagcgt gtatatgatt aacaagaaaa
    41041 cagggaaacg tattttcagc agtaaagacg aggtaattcg ggatttgagt gaaaactttg
    41101 aaccaattga attatttttc catcagttaa atctagaaat tgaaaaatta ctaaaggaac
    41161 ctacagaagg acgaattaat aaagtattga aattaatagc atgtaaagat agtcatgctt
    41221 acatgcttta tccaaaatgg tatgcagaca aaaatatagc tgaaataaac gattatctag
    41281 ctagtataaa ggaacgcaat gcaattaatt aacaatagac gaaaaatgaa attaaaggag
    41341 ataggaaaat ggcagaagtt aaatttggat caaaagaatg gtttgaagag ttaaactcaa
    41401 tgattcagtt tccagaaaag tttacttttt actacaacaa aagagacaat atcattcaag
    41461 tagctttact tgaaactaag ggaagattag aaaatactcg atggagtatg ataaaaccat
    41521 cagcactcag atttcatcct aaagacttga cagcggttgt agcggtaaaa gaggttcaag
    41581 actcacaaga atactatgaa gtagtaaaaa atctgaagga tatctggtgt aaataattct
    41641 aaattgacca gttatttggt caaaaatagt atgtgattat ttcatccaat atggcatcat
    41701 aattggtatg aaaggggata aattatttga aagaactaga aggtattaag aaaagaaatc
    41761 aggaaagatt ggaactgtta aatgaaaata gaaataggat gtttagttac tatgaatcca
    41821 tgaggtgttt aaataaatct agaagtgaaa ttatagaatc atcaaagtat aaacaattga
    41881 tggaagagag agtttctctc attcaagaaa tagaaacaga gtctattttt ccagatcatt
    41941 ttcctaaagt ccgattttat aattaaacat taacaaatga aacgatgcta aataggcatc
    42001 gttttttatc tatttgttaa atttgtttat ttacaaaatg tgtatcggtg tgtataatat
    42061 atttgtagat aagtcaagaa aggatgatct gaaatgaaat tagaaggtag cttacaaaac
    42121 agaatgatgg aaggcagaac aacaaataag gagattgtag ttggtatggg agcaaccgag
    42181 cttctatata ccgacagaaa tccttataca gtgattgaag taaaaagcaa aaacagaatt
    42241 ttggttcaag cggatggggc aatcaataaa gctacttttc cagatcaaga gtgggaatac
    42301 agcagaaatc ctgaaggtca aatattggaa ttaattaaga caaaaaatgg atggaaagtg
    42361 cttaaagaaa atactcattt ttatataggt gatagagaaa aatactacga tcctagtttt
    42421 taaacaaact gaagatgagc gaggttttat cctcgctcag aaaggagtat gaaggatgtt
    42481 cagtcaagaa gaaatcatca gcaaatcgca accggataaa aatggaacta taaccatgaa
    42541 gaaaaaaatt ccttgctatc gttgtagcgg atcaggtcag tacaagttta tgtctatggg
    42601 gaaaattacc tatggcacat gctttaagtg cgatggtgac ggatttcttg ttgtaactga
    42661 aaaatcattt acgccagaat atagagctaa gctaaatgct ttaaataaaa aaagggctga
    42721 tcgaaaaata aggatcacaa gagagaaaga atctcagaaa aattttgatc gttatggttt
    42781 tgaaaagggt tatatttacg tggttataga ggaaaatagc tatgcgatca aagatgaact
    42841 gcatcatcaa ggagctactt atgatccttt attaggttgg tttttcaaag aaaaacaaga
    42901 acaatacaaa actcaaaaag tttttgtaga agaattttcc gtaatcaatg atgaaggaat
    42961 tattgaattg aagctagaag aatacagcga aagacaacag gagattttaa gggcgaagcg
    43021 tagagaagag ggtgagttta ttggtacaat cgctcaacga ttggaattgg atttgaagct
    43081 taccaatacc gtcaccatag atacacaatg gggcaatgtt tatctgcatt tatttgaaga
    43141 tcaaaaccat aattcattga tttggaagac aaataaattt ctttattatg atgaatggga
    43201 tgttggagaa ataaggaaag ttaaagcgac aataaaagcg catgactact acagagatac
    43261 caagcagact tgggttaaaa atgttaaaat tcaaaaaaat gagtcagaag ggataaaagt
    43321 atgaaaagag aggaatacaa acaaagatta aacgaactgc ttgaagagga cgaaacatta
    43381 actcatggtt cgcctgatga aattctatac atgattgata atatggtgat ctttggtgga
    43441 tatgaacttg gtaataggtc agttgatcat aatattttag aatttgatga tgtatcatgg
    43501 gaagaaattc ttgattgggg aattttggcg gtacctgaaa ctaaaaccta tattagtgac
    43561 actatggttc ctttttttga ggaattggat tataaaagac ttcccaaaaa tgaaaatcat
    43621 atactgggag gaaactaaca atgttaagtg acttatttat tttactgatc tatctaggtg
    43681 taagtgaaat tattgcgtat tttttgtttg tcattgctaa ttatggtatt tccagtgcaa
    43741 tctttcaaag gtttagatta ccagtaagtg aactaaaaaa aatgatgaga ttatcagcat
    43801 atcttttaat gtttttgaat gtggtcacgt taatctttgt agtaatcggt gtgactttca
    43861 atttaatgga atagagggaa atctataatg gaaaaaagag aaaagaatga acatattttt
    43921 tgaatcaata ttgttgatgg tttttgcgat cagcgcttac cag
//
LOCUS       DACBZK010000015        42800 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.015, whole genome shotgun sequence.
ACCESSION   DACBZK010000015 DACBZK010000000
VERSION     DACBZK010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42800
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.015"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(113..1819)
                     /locus_tag="IVD66_000903"
     CDS             complement(113..1819)
                     /locus_tag="IVD66_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin/fibrinogen-binding protein"
                     /protein_id="HAP6145147.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            2009..2632
                     /locus_tag="IVD66_000904"
     CDS             2009..2632
                     /locus_tag="IVD66_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145148.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            3082..4131
                     /locus_tag="IVD66_000905"
     CDS             3082..4131
                     /locus_tag="IVD66_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6145149.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            4128..5009
                     /locus_tag="IVD66_000906"
     CDS             4128..5009
                     /locus_tag="IVD66_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6145150.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            5012..5782
                     /locus_tag="IVD66_000907"
     CDS             5012..5782
                     /locus_tag="IVD66_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6145151.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKGARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            6061..6915
                     /gene="aroE"
                     /locus_tag="IVD66_000908"
     CDS             6061..6915
                     /gene="aroE"
                     /locus_tag="IVD66_000908"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HAP6145152.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            7093..8256
                     /locus_tag="IVD66_000909"
     CDS             7093..8256
                     /locus_tag="IVD66_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAP6145153.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            8373..8783
                     /locus_tag="IVD66_000910"
     CDS             8373..8783
                     /locus_tag="IVD66_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP6145154.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            8957..11185
                     /gene="topB"
                     /locus_tag="IVD66_000911"
     CDS             8957..11185
                     /gene="topB"
                     /locus_tag="IVD66_000911"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP6145155.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            11323..11640
                     /locus_tag="IVD66_000912"
     CDS             11323..11640
                     /locus_tag="IVD66_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145156.1"
                     /translation="MKKVHSFLNYLMGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAY
                     SPTLILSTLTAGAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQ
                     YFG"
     gene            11800..12036
                     /locus_tag="IVD66_000913"
     CDS             11800..12036
                     /locus_tag="IVD66_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP6145157.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            12033..12431
                     /locus_tag="IVD66_000914"
     CDS             12033..12431
                     /locus_tag="IVD66_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAP6145158.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQT
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(13098..14042)
                     /locus_tag="IVD66_000915"
     CDS             complement(13098..14042)
                     /locus_tag="IVD66_000915"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAP6145159.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(14338..15282)
                     /locus_tag="IVD66_000916"
     CDS             complement(14338..15282)
                     /locus_tag="IVD66_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6145160.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            15503..16717
                     /locus_tag="IVD66_000917"
     CDS             15503..16717
                     /locus_tag="IVD66_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6145161.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            16739..18754
                     /locus_tag="IVD66_000918"
     CDS             16739..18754
                     /locus_tag="IVD66_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HAP6145162.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(18837..20210)
                     /locus_tag="IVD66_000919"
     CDS             complement(18837..20210)
                     /locus_tag="IVD66_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAP6145163.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(20236..20520)
                     /locus_tag="IVD66_000920"
     CDS             complement(20236..20520)
                     /locus_tag="IVD66_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6145164.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(20522..22537)
                     /locus_tag="IVD66_000921"
     CDS             complement(20522..22537)
                     /locus_tag="IVD66_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP6145165.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(22716..23021)
                     /locus_tag="IVD66_000922"
     CDS             complement(22716..23021)
                     /locus_tag="IVD66_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HAP6145166.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(23110..24141)
                     /locus_tag="IVD66_000923"
     CDS             complement(23110..24141)
                     /locus_tag="IVD66_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAP6145167.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            24348..25223
                     /locus_tag="IVD66_000924"
     CDS             24348..25223
                     /locus_tag="IVD66_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP6145168.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(25375..26217)
                     /locus_tag="IVD66_000925"
     CDS             complement(25375..26217)
                     /locus_tag="IVD66_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP6145169.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(26309..28186)
                     /locus_tag="IVD66_000926"
     CDS             complement(26309..28186)
                     /locus_tag="IVD66_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP6145170.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(28183..29604)
                     /locus_tag="IVD66_000927"
     CDS             complement(28183..29604)
                     /locus_tag="IVD66_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP6145171.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(29607..32996)
                     /locus_tag="IVD66_000928"
     CDS             complement(29607..32996)
                     /locus_tag="IVD66_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAP6145172.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            33253..34644
                     /locus_tag="IVD66_000929"
     CDS             33253..34644
                     /locus_tag="IVD66_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP6145173.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(34717..35364)
                     /locus_tag="IVD66_000930"
     CDS             complement(34717..35364)
                     /locus_tag="IVD66_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6145174.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(35372..36058)
                     /locus_tag="IVD66_000931"
     CDS             complement(35372..36058)
                     /locus_tag="IVD66_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6145175.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(36064..37137)
                     /locus_tag="IVD66_000932"
     CDS             complement(36064..37137)
                     /locus_tag="IVD66_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAP6145176.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            37359..38033
                     /locus_tag="IVD66_000933"
     CDS             37359..38033
                     /locus_tag="IVD66_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6145177.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            38038..39378
                     /locus_tag="IVD66_000934"
     CDS             38038..39378
                     /locus_tag="IVD66_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP6145178.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(39527..40513)
                     /locus_tag="IVD66_000935"
     CDS             complement(39527..40513)
                     /locus_tag="IVD66_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HAP6145179.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            41237..42268
                     /locus_tag="IVD66_000936"
     CDS             41237..42268
                     /locus_tag="IVD66_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP6145180.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            42377..>42800
                     /locus_tag="IVD66_000937"
     CDS             42377..>42800
                     /locus_tag="IVD66_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAP6145181.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQI"
BASE COUNT        13200 a         7767 c         8058 g        13775 t
ORIGIN      
        1 aagaggggtt gtgacagaat tttgtcacaa ctcctctttt tgtagcaaac aatttataac
       61 taattgctgt tgtgggaaag tacgcaaata tgattctaga aacactcatt gattacctgt
      121 tttgtttcat agctgtaatt ttttcttctt ctggtgtcac gataatcgtc ttttggtttt
      181 cataaataac ataaccaggc ttggcgccat ttggttttcg gatatgcttt acctgtacaa
      241 gatcaaccgg cacttgggca gagtatcggt attttgaaaa ataggcagct aactcggcag
      301 cttctgtaat tgtttcatct gagggcttgt cacttttaat gatgacgtgc gaaccgggta
      361 tattttttgc atgaagccaa tagtcggttt ttttagctgt cttcattgtc agctggtcat
      421 tttgaagatt gtttttacca acaagaatga gcgttccgtc agaagaaaag tattgatcag
      481 gctgagatgg tttcttacgt ttttgttttt ttaagttctt ctttttcagg tatccttctg
      541 aagtcaattc ttctttaatt gcttcgatat ccattgggcc ggcaatttcc agttgagata
      601 agacagattc aagatattgg atttcatctt tggcttcttg gatttgttcg ccaatcagct
      661 taacagcgtt cttcagcttt tggtatcgat ggaaatattt ctgtgcattt tgatttggtg
      721 tcaatgccgg atctagtgct attttgattg gccgatcttc ttcataataa ttaggtaaaa
      781 caacttcttt tgcgccgcgt ggtacttgtg tcagaaaagt agtaagtagt tcgccatttc
      841 tacggtaatt ctcagcgttt tcggattctt tgagtgtttg ttcacgtttt ttcaatttat
      901 ttttatttcg ttttagttca ttttcgattt ttcgaatcag ttctccgcct tgttgttttg
      961 cccgatcttt ctctgctttt tcgtgataat agctatctaa taattgactg agtgttggat
     1021 aagctgttac agcagatgcc tgttcggaca atacctgata agcaatcggt gtgaaaaaat
     1081 ctttattttc cgtttcgtaa aaagtaggaa taggctgatg gctgatggct gagaaaaatt
     1141 cgtcccatac aaccatcttt tcattaggac gttccagtaa tcttttggtc agctcttgag
     1201 cgatatcgaa accgattccc tgaaactgac gttggattgc ttttggatct agttcagttt
     1261 gggaaagccg ctgaaagatt ttttctttct cggagctaaa tgggttcaag acctcttgtt
     1321 ttggcggagc aacatattct acaccaggaa gcaaagaacg ataagtgttt tgagagcttc
     1381 caatgtgttt gatcgcatcc agtatttttc cagtttctcg attaactaag acgatcgtac
     1441 tatgacgtcc cattaattca acgatcaata tgatattttg tagatcaccc aactcgtttc
     1501 gtttagcaaa gtggaaatgg atcactcgat cattttcgat ttgttcgatg tcttctaaaa
     1561 tagcgccatc caaatatttt cgaagcatca tcacgaagtt aggcggatta tcaggattct
     1621 gataatcgat ttgggtaatc tgtacacgag cataacttgg gtgcgcagat aataataatc
     1681 gatggttttt gccgcgtgaa cgaatcacca gcacgatttc attttcataa ggctgatgga
     1741 ttttcgagat ccggccagat agtaacgttt cacgcaattc gttgaccatc gcgtgggtaa
     1801 atacaccatc aaaggacatg gttcattcct catttctttt cataagtata ttcattataa
     1861 cgaaaaaaag aagaaaaacc aatttggccg aatagtaaag caaaagtcta gaaaaatctt
     1921 ggactaatta cataaaaaac agtgtttcta tcgttgaaat ccaaattttt aggtataata
     1981 aaaaatagga gaaaaagtag aaaagaaggt gtttgttatt tgggaagtag ttaaatcgag
     2041 agtacaagaa atgaatgaac atttctcagt gtcattcgca gaaaatccaa gtaagtattt
     2101 tcgacgtctt gtttttctgc tcatcttatc attgctgtta acagttgcaa tgtttttatt
     2161 gccggaaaaa atccgagaag agcaagtaaa tagtctcgtt tattcgtcca taccaaccag
     2221 caaattgaaa ccttttgatt acagcaaagc tgatcagaaa atcaaacaaa gccgggcgat
     2281 atcggtgatg ttcagcaaac cgaacgggaa aacctatcag gacatgcttg atgtttttaa
     2341 tgatcctgag cttatggaag aattgaatcg accgatcttt tattatccga tcgtttatga
     2401 tgtacatgaa ctggaacaaa aatataacat acgaacggat gaagtgacat ttattttctt
     2461 tgatggagga aaagaagcaa atcggataac tgcgggtaag ggaggaataa ctgattttga
     2521 taaggagttg atccctgaac tgaatcgact tccgttagcc aatatcaaac aattagaaga
     2581 agaattggat agaacgggag taacttccca aaattccgag attgctaatt gagacattgg
     2641 cgcgatgaaa cggtgggtct atatagcgct atttttaatt atcagaacaa gtgatgtttg
     2701 atcttcaaaa taacaaataa aaaattaaaa aatatagttg acgaaattca aaaattcgat
     2761 ttgacttaaa tcaattctta aggaaagggt gacctgtaat gaacttatca aaacgtattt
     2821 cagcagaaaa caaaaaaaat tggcgcagct ggcgtagata agttgtatta atggtgagac
     2881 tttcccatag atacaacttt ttagagtgca tttctaaagc ttgtatctat gctagacatg
     2941 aacattgact gccgcataga ttagaatcta tgcggttttt tgtgtaaaga caatgaccgc
     3001 tttggccatt gtcttttttt gtagactgga tacttgcctg attataataa ataaaaagat
     3061 tgactttgca ggaggaaaaa aatgaaaaac aaacgattaa taacagttgt agtaattatt
     3121 ttagtttatt tagcaggtgc atttatttat ggaaaagcct caggcgaaaa agaaagtact
     3181 tcgacgaacc agacaaaaaa aacaacagtt gttggggtat tgcaatacgt gagccatccg
     3241 gcattagatg agatttatcg aggaatcaaa gatggtctga aagaagaagg attaaaagaa
     3301 ggagaaaatc ttgagatcaa atttcaaaat ggacaagccg atcagagcaa gctagccaca
     3361 atgagtcaac agctagtaca atctgatcca gatgccttga ttggaatcgc aacacctgcc
     3421 gctcaatcat tagcaaacac gacttcatcg atcccagttg tgttaggtgc tgtaacggat
     3481 cctgtggggg ctggattagt cgcttcttta gagaaacctg gtggtaatgt aacaggtgtt
     3541 tctgatcagc cgcctgttac ttcacaaatc aagcttgctt ctgatttgtt gccaaatgca
     3601 aaaaaagtcg gaatcttgta tgcttcttca gaggataatt caaaatacca agtagcacaa
     3661 gcagaagaag ctgcaaaaaa agaagggtta gaatcagtaa aatatgcggt gccttccact
     3721 aatgagattg cacaaacggt tcaagtgatg agccgacaag tcgattttat ctatgttcca
     3781 ttagataata ccattgccaa tgcgatgcaa acagtggtaa aagaagcaaa caaagcaaat
     3841 atccccgtca ttccatctgt ggatacaatg gtggaacaag gtggactagc aacaatcggg
     3901 atcaatcaat atcaattagg gcttcaaagc ggtaagatgg cggcagaact tgcgagtgga
     3961 aaagaaaaac cggaaacgac gcctgtttat acatttgatc aaggggatac agtgatcaat
     4021 caatctcaag ctgatcgctt aggaatcatt gttccccaat cgatgaagga aaaagccaaa
     4081 atcattacag atgactcgca gcaagaaaca tctaaggagg atgacaaatg atcgtatcag
     4141 ctatttcaca aggcatgctt tgggcaatat taggattagg gattttcatg acttatcgga
     4201 tcttagactt tcctgatatg acgacagaag ggtccttccc attaggtgct gctgtctgtg
     4261 tgacagctat tactcatggg gtagcgccga ttgtagctac attattaggc gtaggtgctg
     4321 gcatgatagc aggactcgtt acggggttac tttatacaaa aggaaagata ccggttattt
     4381 tagcagggat tttagtgatg tcaggattga actcagttat tttgtttgtg atgcgaacac
     4441 caaatctttc tttattgaat catccgattc tacaagacag cttccatcgc tttgggttac
     4501 ctgattactt tgacacagtc cttcttggct tcatctcttt gggcatcttg attgctgtac
     4561 tgctattctt cttcaataca gatttgggtc aaggctatat tgcgacagga gacaacgaaa
     4621 cgatggctcg gtcgttaggg ataaaaaccg atcgtatgaa aattttaggt ttaactttgt
     4681 cgaacggtgt cattgcatta tccggtgcgc tgattgccca gaacgacgga tatgcagatg
     4741 taaataaagg gattggcgta atcgtcatcg gtcttgcttc catcatcatc ggtgaagtga
     4801 tcttccaaga attgacgcta gcagaaagat tgattgctat tgttgtcggc agtatcattt
     4861 atcagctatt gattttagta gtaatcaaac tagggtttga cacgacttat ctgaagttgt
     4921 tctccgctat catcttagct atttgtctga tgatcccgca attgaagaaa gcactgaact
     4981 taaaaacggg ttttgagaag gaggcatagt aatgactgat atattgacaa tcaaaaatgg
     5041 cagaaaagtc gtaaacaatg gaatgaatga agagaaagta ctattggatg aaattaacct
     5101 tacaatcaga gaaggggact tcatcactgt ccttggcggg aatggtgctg gaaaaagcac
     5161 actgttcaat acgatcgctg gtacgcttca actcagtcaa ggatcgatct cttttaaaga
     5221 tcagctgatc acaaaagatt cagaagaaaa aggagcacga ttcctttctc gagttttcca
     5281 agaccccaag atgggaacgg ctcctcggat gacagtagca gaaaatttgc tacttgcaca
     5341 aaaaagaggt caaaaacgga aattccgttt acgtaacttg aaaaatcaaa aagaagattt
     5401 tttcagacta tgtcaagaag tcggtaatgg cctagagcaa cacttggata ctccagcggg
     5461 tgaattatct ggtggtcaac gccaagcatt aagcttgctg atggcgacga tcacagctcc
     5521 tgagttacta ttattagatg aacatactgc agctttagat cctaaaacag ctaaagcatt
     5581 aatgcgatta acaaatcagc ggatcaatga acaaaaattg acttgtctca tgatcacgca
     5641 tcgaatggaa gacgccttga aatacggaaa tcgtctgatc gtactccaaa aagggaaaat
     5701 cgttcaagat atttctgaaa aagaaaagca acatttgaca atgggcgacc ttttgcagtt
     5761 ctttgaagaa gtagtggatt gatttcgaca gaaaaattcc tttcagtaga aggacttgaa
     5821 aactcattga catcttcctt tgattcatcc tatacttaaa acaataaaca attaaacata
     5881 tttgggtgtt ttgtaggatc acgtagtcaa tgattttaac aattaaatag aatattcttt
     5941 gctctgacaa gtaaacgatg agaaaagaat ttgctacttt gccacctaga cgtttcgtac
     6001 tttttcgtat caaacgctaa gtggcttttt ttattgaagt aagaacaaag gaggaataag
     6061 atgatttctg gacaaaccaa attagctggg ctctttgctg atccggcttc tcacagttta
     6121 tccccattga tgcacaatac tgcttttgaa gcaaacaaca tcgatgcggt gtatttagct
     6181 ttccaagtaa atccaatgaa tttgaagcaa gcagtcgaaa gtattcgaac ttttgatatg
     6241 ttaggtgtaa atctttcgat gccgaataaa acagcggtta ttccttatct ggatgaggta
     6301 agccaggaag cgcaattgat cggagcagtg aatacgatcg tgcacgaaaa gggtcgtttg
     6361 attggctata atactgatgg tgcgggcttc atgcaatccg tgcaagaagc tgggatttcg
     6421 atcaaaaaga aaaaaatgac tctactggga gctggaggtg cagcaaaggc agtcactgtt
     6481 caagcagcgt tagacggcgc tgaggaaatc gtagtttata aacgaaacaa ccaaacattc
     6541 gctcaagtaa aagaaacatt cgaacaactc agctatcgaa cttcttgtaa gataaaagtt
     6601 cgtgactttg ccgatacgca tcaattaaga aaagacttga aagaaagctg tcttctagtc
     6661 aatgcaacag atatcgggat gggaaagaaa atcaatcagt caccgctctt agatataagc
     6721 atgatgcatg agaatctagc ggtttttgat ttgatttatg cacctagaga aacacgttta
     6781 ttaaaagaag caaaaaaagt aggagcaaaa ggatacaatg gacttggcat gttgatctac
     6841 caaggagcaa tcgcgtttga attatggaca aaggaaaaga tgccgatcca tgtgattgaa
     6901 aagctgtttg attaaaaaag gataatagat aaagatcttt tattctcgca taaacggtct
     6961 caagaaaagt aatcctttat gtatcgaagc atttatttcg ttatttttta ttaaattatc
     7021 aaaaaatgat aggcttttgt cgattggtta tcgtatcctt tatttatcag taagaaacga
     7081 ggaggaacca caatgagtcg gatggatcgc tataaggaca tccataagaa ggcgaaacct
     7141 ctgaagcggg atacggggag tatttttgct agaagagaac gaaaacgaac gcgtatggaa
     7201 aatgaggaag atgctacccg tatttatgaa agagagcagc attcatttga acatttgaac
     7261 caatacgagc aacagatata cagagatgca ccaagagcag aagaacaaca aaaaaataaa
     7321 aaatttttca atcggcaaaa gaagaacaaa ccgttaaaac ctcgaagaaa gcgatcgtgg
     7381 aaaaaaatca ttctatcgat tttgcttgtt ttgatccttt attcaggtat ctcatttttt
     7441 attggtaaat atgtagctga acatgacaca agcttagagg cagcgacttc agaaaccttt
     7501 catgggcaaa aagcgacgaa tggtgcgcat aatattttga tccttggaag tgatacacgc
     7561 ggagaagatg ccgggcgagc cgatacgatc atggtcttac agttggatgg tccttcccat
     7621 aagccgaaac tgatttcttt tatgcgtgac agcttcgtta cgatcccagg ggtaggacaa
     7681 aataagatca attcagctta tgcatacgga ggagccgatc tagtgcgtca aactttagta
     7741 gaaaattttg gaatcgattg tcaatactat gcgaaagtcg atttcaaatc gtttgaaaaa
     7801 gtgatcgatg ccttattcat gaacggagtg aagatcgatg cagaaaaaga tctgaatctg
     7861 gatggtgtag atattaaaaa agggggccag aagatggatg gacatgttct tttgcagtac
     7921 gcacgtttcc gaatggatga acaaggagac tttggccgtg tcagacgcca acagcaagta
     7981 atgaacgcta ttttcagcca attgaagaat ccattgaatc tgatccgtgc accttatgca
     8041 gctggtaaag ctttaggata tacatccaca gatgtcactg cttggttctt gacgaaaaac
     8101 ctcttttcga ttgcacgagg agctggtggc attgatcgaa taagtgtgcc agtagacggt
     8161 tcgtggaatt atgggcaaag tgattatgct ggcagtattc ttgaaattga taatcaaatg
     8221 aatcaatctg ctattacaga ttttttgaat aaatgatcat aaaaaagatc aagaagaagc
     8281 tgcgcaaggc ttttgtcatg aatcaatcaa acgattcact cgtaaaaaac gctttcttat
     8341 ggtagattta accaagagag gagctgttta cattggatat ctatctgaac ttcaaaaatg
     8401 agtcgcgtga agccatcgct ttttatgaaa aagtttttca gactgaagca tcaggtatca
     8461 ccacatacgg tgaaatgcct ggaatagaac aaatgaactt gccagaagaa gcaaaaaatc
     8521 taatcacgaa tgcacggctg aacatttatg atacattagt tatgtttgca gatacgccag
     8581 aaggaattgg tcctgaatta gttgtgggaa ataatgtttc tttagtcatc cagacaagaa
     8641 atgaagaaga aacgaagcgc ctatttgaaa gcttagctga gggtggtaag attgagatgc
     8701 cactggatgc tgttccgtgg gctcagttgt atgggatggt aactgatcga tttggcatca
     8761 actggcagat taaccaagag tgacagctaa agatgaatat tttctggaaa catcaagcag
     8821 caaacggatc atcgtttgtt tgcttgatgt ttttgtgtct atttcgacta tacggtatct
     8881 tttttttatt gccagatgcg aaaatatgtt ccataataga gaagtccgca aaaaattaag
     8941 taacggaggt cagaagatga agacggtgat actagctgaa aaaccttcac aagcaaaagc
     9001 ctatgccgaa accttccaac agcaaaagcg gcatgaaggg tattatgaaa tcagcgatcc
     9061 attgtttgct ggtgaagtaa ccatcactta tggttttgga catttggtag atatggttgc
     9121 tccaggagct tatgaagagc gttgggcaaa atggtcttta gaaaatttgc ctattttccc
     9181 agaaaccttc cgttacgaag ttccaatgga caaacgtgca caattttcga tcgtaaaacg
     9241 agaattgcag tcagccgata ccatcattat tgcaacagat ggtgatcgag aaggtgaagc
     9301 catcgcgtgg tcgattattc gacaagcaaa cgcattttct aaggaaaaga actatttacg
     9361 tttatggatc aattctcttg aaaaagaagc aatctatgaa ggttttaaga atctccaacc
     9421 tggaaagaac tattttccaa aatataaaga agcgcaagca aggcagaacg ctgattggct
     9481 gattggaatg aatggaagtc cattatatag cttgctactt caacgaaaag ggattgatgg
     9541 cagtttttct cttggtcgtg tacaaacacc gacactctat atgatttatc agctgcaaga
     9601 agaaatcaaa cacttcaaaa aagaaacgta ctttgaagga gaaggtttaa ttacgacaaa
     9661 caaagggcag ttttctggaa aaatcgtacc aaaaaaagca tttaaaaccc aagaagagtt
     9721 aacgaaggaa atagaaaaac ttggagcgca tttaggtaag caaaacggac ggattcttga
     9781 agttacgaaa aaggaaaaga ggttgcatag tccacgttta ttttcgctat ctagtttgca
     9841 gacaaagatg aatcagctaa tgaaagcaag tgccaaagct acacttgatg ctgctcaagg
     9901 attgtacgaa agcaagtttc taagctatcc aagaacggat tccttttaca ttacagaaaa
     9961 tgagcatcag tatctggtta aacatctgca aaattataaa aaatttttag gaatagaaga
    10021 agtacagaca actgagatca aagcaaagaa acgatatgtc gatgcgaaaa aagttcaaga
    10081 acatcatgca attattccga caaagacgat tccgactcct gcacgctttg cgaagctttc
    10141 caaattacag caagcaatct atttgcaagt tttgcgcact actgtggcta tgtttgctgc
    10201 agattatatc tacgaagaga cgaccgtaat gacgggcgta cagcaattaa agctaaaaag
    10261 catcggaaag atcccattac agcaaggttg gcaggaaatc ttacgcatca agtcaaaaaa
    10321 gaaagaagct cagactcttc ctcctatcgt agaaaatgaa gaagcagaag tagaactgaa
    10381 aagtatggag aaagaaacac aacctccaaa accctatacc gaaggaacgt tgatcacagc
    10441 aatgaaaact gcgggaaaaa cgctggataa tgatgaagcg caagaaattc tcaaagaagt
    10501 agaaggaata gggacagaag ctacacgagc caatatcatt gaaaatctta agcagaagca
    10561 ttacatcgaa gtcaataaaa acgaaataac tgttacgcca aaaggaatca ctctttgtaa
    10621 ggcagtagcc aatgaaccat tactgacgag cgcagaaatg actgcgcgct gggaagggta
    10681 cttgagaaaa attggtaaac aagaggggac accatctgtt tttttagaga atatcaaaaa
    10741 attcatccta catttattgg cagaagttcc taatcaaatc gacaaggtag acttttcaga
    10801 tgagattagc gggacacgtc agataaaagc gatggagaag aaaaacgatc aattaggaag
    10861 atgtccaaaa tgtaaaaagg gaatagtcat gctttatcct aaaatcgcta catgcttgaa
    10921 tccggaatgc gacttcaaat tgtggccaac agtagctaaa aagaagctga ctaaaacgaa
    10981 tctcagagat ttgctttcaa aaggaaagac aagtaaagtt gtcaaaggtt ttactggtaa
    11041 aaaagggaaa ttcgatgcag ttttagtatt aaaagaagat atgacaatcg gtttttcttt
    11101 tccatggatc gaaaacagtg gaacaaaagc agttgatgga aacaaagaaa catcaagaaa
    11161 aaataatgaa aacgaagtag agtaaatgaa aacaatgaaa tagcggaata tttattccga
    11221 aaagtgagaa tataaatacc aataaaacta aaaaatatca gtgaatcaag caaaaacgtt
    11281 ggggtaggct gattttatat agatagcaag gagttttttt atttgaaaaa agtgcattca
    11341 tttttaaatt atcttatggg agcaatcacg attgtggctg tgtaccaagc atttctaaag
    11401 tatcctgatt acgggacgaa gttgttgtca ttgacgcaca atcaaacagc atattcacca
    11461 acgttgattt tatcgacttt gactgcagga gctaaaagcg ctacttattt ttttcataaa
    11521 acgacaagca tgctaaagcg aaagaaacag cgaaaacaat tgttggtggt ggtagcggct
    11581 atgatcatta tttattttct accagttatt acacaagtat ttcatcaata ttttggttaa
    11641 gaatacgaga gtttgtgaca aaagtcatgt cacaaacttt tttctttgtc attttttcgt
    11701 aagaaaaagc aaaataaaag tatatacatt gattaaaagt atatacttgg atataatgta
    11761 cttactatag aatgagaatg gtatagaggg tggcgaaata tgaaaaaaat gaaaaagtat
    11821 aaaattagaa aatctggcaa tagcgatgta acaactatcc caccagaagt aaaagaattc
    11881 atgggtgtgc agacaggtga cgcaatcagt tatgtttttc aatctgatgg ttctgtacga
    11941 atgatcaaag cacaagaaga acctgatatt gattcattag ttgattcgat catgaatcaa
    12001 tatgaagacg cgttaaaaga tttggttgat ttatgaggta tctttcgact aaagaaatta
    12061 tcaaaatcaa cgcgaaagtt attttacgtc actcgccagg cgaaatgatc ggtgtaaaag
    12121 atgcaaatgc attagatatg gccgtcaaac agccttcaca aacagtattc aatcaagaac
    12181 tctatcctga aatctatgaa aaagcggcga ttttagcaat taatttagct aaaaaacatc
    12241 cttttcataa tggcaataaa cgaactgctc ttgttgccat gttgttgttt cttcaattga
    12301 ataattgtcc agttgctttt tctcgtcaag aagctgttga ttttatcata atgattacca
    12361 ctagttcatt ggatttcgat tcactaaagt ccaagataac cagttattta cgacaaaccg
    12421 caataaaatg aacgaattaa aaactttatt tctcaattag atcagcatgt cattaaggaa
    12481 tatgctgatt tttttatgtt taatcataca aaatagtttt ttcataaaaa tatggaaaat
    12541 atggattaat tttgaaataa ttgatttaaa aggaatacaa aagagtgaat agtaggaaat
    12601 agtggtttag aactagtggg ctgatttttt atatatttta gtttacataa tatatattat
    12661 acaaagtaga tttaaaaaat gataaacctc tctcgaacgg ttttttatca aaaatcgtca
    12721 tttttccatc aaaatctgct tatgcaaaat tataaaaaaa ttttgcagtt tttcttactt
    12781 tttttgtcgt ttaattgaat gataaaaacc agtttcttta ttcagttaat caaatatgaa
    12841 cgaattagat atgaatcatt gtatttgccg ttgcggaagg attttttaat taaccacaga
    12901 taaacattga taacgattcg cttattgtaa tcaacagatt aaatttcata tgttcatatg
    12961 tacggataca ttttcggacc gattaatttt aaccattctg tttatttgct tacctattag
    13021 atatcaataa aaaactgctt aacagctatt tcagctgtta agcagtttta ggatttttag
    13081 ttcatattca ttgtttctta taatacagtg ttcaatactt ctcttaaagc acttgttgat
    13141 ttgctgaaca ttgctttttc ttcttcgttg attgataatt caacaacttc acgaacacca
    13201 ttttcgtcaa cgattgatgg cacacctgta aagatatctt tttcgtcgta ttcaccagtt
    13261 aaataagcag atacaggcaa tacagcttgt tcgttattca agatagcttt tacgatacgt
    13321 gcagtactca taccaatacc atagtaagtt gcttttttac gatcaatgat ctcataagca
    13381 gcattacgga ctttatcagc aatcacatct aattcatctt gggcaatacg atggtctttt
    13441 tctacaattt caaacactgg tttaccaccg acagttgtat gtgaccatgc agcaacttct
    13501 gaatcaccat gttcacctaa gatatagccg tggacgctgc gtgggtcaac ttttaatttc
    13561 aatgcgattt ctttacggaa acgagttgta tccaatgttg ttccagtacc gataacacgt
    13621 gatgttggca gaccagattc gttccaagcg atatatgtca aaatatctac tgggtttgaa
    13681 gcaacaacga taataccgtc gaatcctgat cccatgattt cttttacgat ttggcgcatg
    13741 attgacgcat ttgttttaac taaatctaaa cgagattgac caggtttttg gttgatacca
    13801 gctgtgataa caacgatatc agcatcttta cattcttcat agccacctga ccatacagcc
    13861 acattttcat cgccccaagc cataccatct aaaaggtcca atgcttcccc ttctgctttt
    13921 tcttgattca catcgatcaa tactaattca ttagagattc cttggttgat cattgcataa
    13981 gcgatacttg ttccaacaaa acctgtaccg acgattacta ctttacgact tgtttttttc
    14041 atgaataaac agctcctttt cataactatt tgttactttc atgaaaagta tagtcttgtt
    14101 tattcatttt atcaacatgt taattataat agttgttatt ataatttttg atggaaacga
    14161 attcctgaat acgcataaca gataaatgac aaatgtttac acctatatcc cctgataata
    14221 caaccaaaag tttagaactg aaaataaatc caaaaaaatt cgctgcaacg atataataag
    14281 acagcaatcg cacctaaaac aattttcctt catatgcttt agtgaaagat tttcttctta
    14341 atgtttattt ctccattcat tgggagtaca tgttgaatac ttcttgaata atttgaataa
    14401 agaagtcgtt tgtttatatc cgatacgatt agcgatttct tccaacgaaa aactcgtttc
    14461 ttgaatcagt tccaacgcaa agtcgaattt tttctttaga accagttctt gaaaggaagc
    14521 atcaaaatac attttcaatt tattactaag atagaccgga ttgtagccaa aatgagctgc
    14581 tgtttctttt aacgtacaag aagtaaaatg cttatcgata taatctaata ctctaagcat
    14641 ctcattttct gcgcatccat ctgctgatga aaagctttgt tgttctaata aatgagtcaa
    14701 ttcgatcagt aatagtgatg tatagagatt taacgaacgg atcttatgac tgtatgtatc
    14761 aaaataaatc aacagcatat tttcaatcaa atgcgtcaaa cgacttgttt ttccgccgcg
    14821 aaaatgaatg aattgtgtat gttccccttt ttcttttgat gcatttatca aaaaagaaga
    14881 aagtagatta tttgtgcttg ccaaatgatt caatatctct gtagataagg tttcttcttt
    14941 taataagatg ttgattaaaa tatcctcttg ccctgtgtat tcgattcttt gagtagcttc
    15001 tttatcaatg atcaccacgt cactttcttc catctctatc ctttctccat taataatttg
    15061 taaacatgta ccgctataca tataattgat ttcaacaaaa tcatgtgtat gctcgggaac
    15121 ttccgcatat cgacggtgtt tactgatatg aatatttccc tgttgaaata gatcccctcg
    15181 gtggattttt ggcggtgtct gaagatggta agctaagttt aaatcattga tattcattcc
    15241 ttgttcacgc tgcagagttt cgattgattc ttcgttacgc aaaaaaaatg tctaattcag
    15301 ctagttccaa ttgactccct cctttttgta agcggtttct ttcgcttatt agttcacgct
    15361 gtactgctat tatatgcaaa gctatttttg gtttcataaa gactttctat ggttgggaca
    15421 tgaacttcct gtgattccgc tattgagaga ataaccactt catactatat ttttgataag
    15481 cgcttacaaa aatgaaagga acatgcttat gaataaaaag atgatgaaat tttctctgct
    15541 gtcagtctct cttattttga cttctgctgg tgcagtcacg tctgcaattc ccagtatgtc
    15601 agctacttat gccacgcgtt ctttatctgc tgttgaatta ttaacgactg ctccctcttt
    15661 tatggtcact atttttgttt tgattagtag ttttattgct aggaaaatcg gacaaaaaca
    15721 aactgtgatc atcggattag tgattgcatc gatttgtggt atcctccccc tcttctcaca
    15781 aagttacagt attgtcttag cttcaagagc tggactaggt attggctttg gattgatcaa
    15841 ttctttggca gtcagcatga ttgctgcctt ttatcacgga gatgaacgag cctctatgat
    15901 tggttttcaa agtgcatttc aaggatttgg tgcagcttta atgacatttg ttgcaggaca
    15961 gctagtacag ttcggttggc aatatacctt tttagtctac gccatcagct tacctattct
    16021 tgtcttgttt gttttgtttg ttcctacacc tgaaacaact gaacttcaat cgcatggcac
    16081 agccccaaca agacaagtaa tcaaaacgaa tcctaaaatg attagttatg gtatttttct
    16141 cttgctggtc atcgtggtat ataatgctgt atcgattaaa ttagccacag tcctgacgac
    16201 ttattctcta ggaaacgaaa ctaatgcagc gaatatctta acaatcatgc aattggcaag
    16261 tatggctgcc ggagtttgtt ttggctggct tcagacaaaa gcacatcgct atatgcttac
    16321 actttcttta ctactgatgg gaatcggctt tgtattgatt gccactgtga taaacctgta
    16381 tgtgattggg tttggtgcga tcctaacagg aatttctttt tcgttattca ttccttactt
    16441 attcaaccaa gtaagtatcc aagcgcccaa gtacgcggag agtttcaata cttcaatctt
    16501 attggttggc gctaatttag gtactttcat tgcaccatat ggtttgctct ttctctcttt
    16561 tgcttctctt gggagtaaaa cacttgctgt tttcgtcaat ggcagtatct tgctgttgat
    16621 tagcgcgctt attagccttc tagtagtaca caggacgaat agaaagacag tgataagagt
    16681 agatgaagaa ataaaagaac aattgacaac aaaataaatt tgatggaggt cgtgtaaaat
    16741 gacaaatgaa aaacataaag atagatggct ttggtatcct ggagactttg agatccgcca
    16801 tggactgcta caaaatttcc aacgggaaga acgaggtttt gactggccag cgtactggta
    16861 catggatgat tgccatcgga acgtcaagtt taagagatat tactttcttg atcaaccttc
    16921 catgtttaaa gtgacgatcc aaggagttgg gtatgtagaa attaatggac aaaaacatcc
    16981 atgtggaaaa tggctgactt gtccagctgg taaagcaaaa attcgtatct ttgtaggaca
    17041 tacatcaggg ctaccagcga tgtttatcga gggagacgaa gtaaaatcag atattggctg
    17101 gacagcaagt aattttattg aagaatatcc agctggctgg agtccgcttt atgtcgatat
    17161 cgcaaaagat ccaaatcaaa tctattatca aaaagaatgc gtccatccag tcactgaaac
    17221 ggagattggc ggaggaatct tattcgattt tgggcgagca gtgaatggct gtgtagaact
    17281 aatatctctg gatgaccata tcgaatctat cactctatgt tatggagagt ccgatgtaga
    17341 agctatggat atcgattatt gctactataa gcaaatagga atgacaagaa aaatgaaagc
    17401 tcgtaaacgc gcttttcgct atttgtttat accagaggtt tctactggaa tggttcaact
    17461 tcaagttttt catgaatttt tatctctttc gaaacaagct gctttttcaa gcgattcttc
    17521 tttactgaat cagatctggt cagtatcaga agaagccttc aagttatgta gtgatttgtt
    17581 ttttatcgac ggtatcaaac gagatcgctg gatttggtct ggagatgcgt atcaatcatt
    17641 catgatcaat caatatcttt tttttgacga ggaaatcaat aaacgaacga tattagcatt
    17701 aagaggacaa aatgaaatca agcagcatat gaatactatc gttgactatt cgatcttgtg
    17761 gttgattggt atcgaaaacc actatatgat gacgaaagac tatgaatttt tacgcatcgt
    17821 ctaccctaag atgcaatcat taatgagata cttgatggag caaacgaatg aattagggtt
    17881 tatttatggg agagcaaaag attggatatt tattgattgg tctgaaatgg ataaagaagg
    17941 aacgcttgct gcagaacaag tcttattact gaaagcctat cattccatga tcacttgcgg
    18001 agatatctta gctgaaacat atggagagaa cgaaaattat catactcatc tctatcaaga
    18061 aaaatatcaa ctattgaaac aaaacctatt tgactacttt tgggatgaag aacttggcgc
    18121 ttttatcgat tgctatgaat ctgggagaag aaatgtgacg cgtcatgcga atattttcgc
    18181 tgttttattc gattttgcta acaaagacca acagcaatcg atcttaaaga atgtcttatt
    18241 gaatgacact atcacacaga ttactactcc atatttcaaa ttctatgaac aagatgcttt
    18301 atgcaaactc ggacagacga atatcgtcta ccaaacgatt cttgattatt ggggagggat
    18361 gttatctcat gatgcggtaa ctttctggga agaatacgac cctactcaaa caggaaatga
    18421 aaagtacagt atgtatggag atccttatgg aaaaagctta tgccatgcat ggggagcaag
    18481 cccaatctat cttttaggac gctattttat cggtttgtat ccaacaaagc caggttatga
    18541 agaatttatg atacaaccta atctagattc atttgaaaca ctgaattgta cgctacctat
    18601 caaagatgga aagatttcgc ttgaaaaaac aaaagataag atcgtgatta cttctgatag
    18661 aacaggcgga acagtgaaaa tgaatggtaa aagttatcct cttctagcaa aacagccact
    18721 tgtcttaaca agctattcaa aaataaatgc ataaaacaaa aaactgcttg cgacatatca
    18781 gaagacttta aatcttcttc tgatattgtc caagcaattt ttattttgaa gtttgcttaa
    18841 ttctgttctt tagaaacaat gtttgttctt tttccggcaa aaagaaagct agataatacg
    18901 acaagtaaaa agaaagcgat gattccaact gtcaaggcta tttgaccgta ttctcctagt
    18961 ttcccaagta caagtcctgg tactagataa tcagtatcgg caaatgtaga agaagcgatt
    19021 ttaagatctc ctaatactgg aaggataaat aatggcagcc aactaatcaa taagctattg
    19081 aaagcagaac ctaataccgc ccctcttcta ccgccagtcg agttgccgaa gacaccagaa
    19141 gcagctccgc agaagaaatg tcctactacc ccaggaatga taactgtagt ttgcaagcct
    19201 atcatagcaa acatggatag tgttcctaca aagaagctaa caaaaaagcc aattaataca
    19261 gcattaggtg catatggaaa aacgatagga acatctaatg ctggtttaga atcgggtacg
    19321 agttttttag caatcccttg gaatgctgga acgatttctg ccaacaccat tcgaacccct
    19381 tgaaggacga taacaaaccc agctgtgaat gttccagctt ggatcagtgc aaagattaca
    19441 gcgttgtctc cattgcttag ttctctttca acaaatccag gaccagctaa caaagcaagt
    19501 gcgacatata cgatcgacat caagagcatg atcgatacag tagaatctcg caaaaagctg
    19561 aaacttttag gaatctttat gtcctctgta gaacggtctt tgtttccaaa aaactttccg
    19621 atccatccac tagaagcata accgatattt ccggtatgcc ctaacgcaac ttgattgttt
    19681 ccagtgatgt tcttcataaa cggttgacaa agagcaggcg taatagttaa tagtgttcct
    19741 tcgaagaccc cgcctaataa gatcatccac aaatttgcag taaaccccgc gcttactaaa
    19801 atgactgctg ttagacaaga aacataaagc attgcttgac ctgtaagaaa aatgaattta
    19861 tatcttgtga atctagcaag taaaatattc acgatcatcc ctactagcat gatcaaagca
    19921 gtaggtgtac cgtattgttg caaagcaatc gccactactg cttcattgct aggaactact
    19981 ccttgagtat gcagagctgt ttggaacatc gaagcaaaag gggttagtga attactgatt
    20041 aaaccagcac cgccgatcag tactaggaat ccgacaaatg ttttgatagt tccttggatc
    20101 acttctgaaa atttcttctt ctgaagaacg agaccaagca gtgcaatcaa agaaacgagg
    20161 atggagggct gactgacgat tgacacaaac aaattcaaca atttatccat tgatagttcc
    20221 tcccttgaat catttttatt cttttgacaa gatcttcgtt actttttctt ttacttcttc
    20281 gctgtcaatg atcgattgca aaggtacgag cttttcatca ggtatagaag ttagcgtatc
    20341 tttcaaagaa tgctcaatga agaaataatc agccatatcg ctagatacac ttccaacatc
    20401 cgtatgactt acttcaaact cgtccacatc tgctccaaga tctgcaagtg cttgtttgat
    20461 gttcatctct accataaaac ttgttcctaa tccactttga catactgcaa aaattttcat
    20521 atcattcgtc tccttttctt atgatcgcta atatttcttc ttttgttgat gcgtgtaata
    20581 aatcttgaag attttgttta ttagaaagta gctttgttaa atttgccaaa gcccgaagat
    20641 gtgcctcatt atcgatagca gctaaacaga tgaacaaact aatgggatgg gctggattat
    20701 caagcagatc cacaggttgt tgaagtttca gcaaagacat ccctacttcg tttacgccat
    20761 cttctggacg agcatgaggt aatgcgatgt gatcgccaat atggataaac gcaccatact
    20821 gctccacgcg ctcgatcata gctttgatat aactttcttc tattttattt tctgataata
    20881 gcggctgtgc ggcaaatgtg attgcttctt gccagttttt tggttgatcc gataattgga
    20941 tcatttcttc tgttaataat tcagatagca taggacgttg atcctccttc ttttctaaaa
    21001 gtttgttcat tttacgattt aatacttgat agagcttttc ttcgtctacg ccttctttta
    21061 attcgatata aggcagtagc gccgacaaca attcttgggc agaaggcatt gaaaatcctg
    21121 gtatcagcca atctctttgt acttgattga tcagctgatt tttttccaag tcagtcatga
    21181 ttggatgcag aacatagaga gactttttct tatcagtaag tgtgagaggt acagtagaaa
    21241 aaataatatc gtaagaagtt tcgtcaacct cgtgtaagcg gtcagctgaa ttagtctctg
    21301 taaaaaagat catcgggaat aattgctgaa gttcactttt taagatcaat gaagagctaa
    21361 tgccacttgg acagacgatc acggctctta tttttctatt tctttcttct gcgtccgctt
    21421 ttctgatctc tccgccaaat agtatagtga aaaaaccaat ctcttcttca gggatgctct
    21481 tccctattcg tctttctaac ggaagtaatg cttttcttgt catttcgtag atggaagcat
    21541 attgatgctt aatttgatcg atcatcacat taggtaaata aaaagaatag gaaatacgaa
    21601 aataggcagg gaccaagtga taaaagacat tcatcaataa ttcacgaaac gaagcaaatt
    21661 ctacggccat caggaattcc atgcgatgga tgacttctga agaacattcc agcaaaaaat
    21721 caagtgcagg ctcctggaca tctccttcaa cgatcgatgc taagcaaaga gagaaaaata
    21781 taatctccga attttgatgt tcggaatagc caaggccagt caatacttgt cgactaatgt
    21841 cagtgactgc aagagaagcc aacagttcag catcttttac cagttccatg gatgtttttc
    21901 caattcgaat ggttgtcaaa ctcaaataat aagctaattc atccattcga tttggtgcga
    21961 atcgaagatc tgatagtgaa atcgttttat ctagcaaatc tctaactttg gcgtaataat
    22021 caatggaaag ggttgcggtt aaatacgtga gcccaaatct tccagcaagt gactgcatca
    22081 aacgagcagt gcgatttttt gcttctcttc ttaatattgc ttctgaccct agcagcctaa
    22141 aaccagtttt cctagtatac gacagctgac aatcttccac ttctaattca tttcttatct
    22201 ttttgatatc tgacaggact gtccctttag aaacctgaag aaaatcttga aaatgaaaaa
    22261 cagaaacaga cgttgcagtc gaataaacca tcaaataaag aagatctctt cgctcttgtt
    22321 cggtatacac agcttcaaat cgagtaatat ccaaaaattt ttctgcccag tcgattgctc
    22381 ggaatttctt tatacggata cgggtatcat ccacatattc ggcaaaagga gttaattgtt
    22441 tgatcgcctc gcttgtattt acttcgatga tctctgctgc tttttctaga ctgatttctc
    22501 ttggtgtttt caggagataa ctaattttgt agttcacagc gctgttcacc tcctacttat
    22561 attctagtat ggtagcgctt ttaaatcgag gggtgtttgg tacaacttac agttggattt
    22621 tttttacgac tgtaccgaac gatttctatc gaatggatac agaaaaaaag caggtgacca
    22681 aatgtctcct gcttttatga attgatttcg tccgatcaat gatgatcatg tttatttttt
    22741 gaggtcagtt cttcaaattt ttctttgaca tcttcaaccg ctttttcgat atctttttca
    22801 aagtgattgg gctcattagg ctttgtttcc tcttctacag aatttgaacc agataaagct
    22861 gtttctttat tttctgtttc accagagttt gtgccagcta atgattcttc tttgtcttct
    22921 gtttcaccag aattagttcc tgctaaagcc acttcttctt ctgttttagg ggccattgaa
    22981 cctcttaatc gtttgtgttt ttcaccgtca taatttgtca tgttggttcc tcctagtagt
    23041 tctatacttt ttcatcgtac aataagacag tttatgcgtc aaaaaacaaa cccgattctt
    23101 acaaatatgt catatttttc cttctgattc ttgaatgctt ttgattcctt cttccaaaat
    23161 tttcatttgt aagattgttt cttcatcttt gatgactttt tctgcgccat taactaatgt
    23221 ctcgtaaatc ccttcgtaga cacggctgta atcaccaacc tcggaaatta ctttttcttc
    23281 atgataactc ccttgttcat ctatataggt caatacacca taatgttcgg gcaaatcgat
    23341 accaaagtct tcatgatcag gcatgtaaaa cattttcaga tgttcttctt gtcgatcttt
    23401 tgtttgtttc acgaacatcc ctttttttcc gtaaacgacg aaacttggac gttctttgat
    23461 gcggaaataa ctggatttta tcgaaatttt catatttcca tagaaaaaat ccagatcgaa
    23521 gtaatcattc attcgtcctt tccctaaaag ttgacgtaca tcatagctga tatcatctgg
    23581 ttcgccgaaa taagaaagaa cttgatctac tgtatgacaa gcatgtccat ataaatagct
    23641 gttcgcagta gaaaattcat gcgtattttc tggtacttcc ggtctgaaat aatcataatg
    23701 catttctact tctaaaatat cccctaattt tccgctttcg attacttttt ggactgtcaa
    23761 gaagtcagaa tcgaaccgtc tgttttggta acattggata aatagacctt tttcttttgc
    23821 taatgcaaat aactcttctg cttcctttga cgtttctgca aaaggtttct ctactagtac
    23881 attcttacca tgttcgagtg ccatttttcc atattcataa tgaaattgac taggtgtagt
    23941 gatgacaact aattggatct caggatcatc ccaaagatca gacagctgat cagtatattc
    24001 gatgtcttcg aatgttttcc acactggttc agatggggaa aaaatttttt tgatattgat
    24061 tttgttcgta agttttcttg aaaaaggcaa atgatagcga tttgtactct ttccattgcc
    24121 aagataagcg attgtaagca tgagtggtgc ctccttttat tgatgttttc agtatatcct
    24181 agaaaagcgc agaaagtatt tataatagct attctggtaa aaaagttcag aaaaacactt
    24241 gttatcattc ggtttggtga aattaatgtt caaagtaagg ataaaaatca aaaagatagt
    24301 agcggaacca agtgtttatc agtaagatag aatttggagg tcagatcatg cttattgaag
    24361 aaaaactaac aaaacaagag ttgtttacca cgacagagaa acggattgtc gattacatcc
    24421 gtaggaatat cgaagctgca gtctacatga cgattgaaga attagcaaaa gctacgtata
    24481 cttcccattc agctatcatt cgtttatgca aaaaaatggg attcagcgga tttaaagaat
    24541 tccgtttcga gctggggcgg gaagttcatc aattgattgc tcagttcaat caaacgattg
    24601 atcctaattt tcctttttca agtgaagata gcactcagca aattgcaaag aaaatggcgg
    24661 atttatcgat ccagtcaata aaaaaagcac aattgcagat tgaacatgaa gatttagatc
    24721 aaatcggtaa agtattgaac aaggcacagc gaatctttct ttttgcaaaa ggtgattctc
    24781 aaatcacggc aaggaaattc cagaataaaa tggtcaagtt gaataagttt ttgatcatgg
    24841 ctgaagaata cagtgattct tcttggaatg cagccaattt gactagcgag gattgcgcca
    24901 tttttattag ctacagcggt cgcatccatc attatgaacg aataatgacc tatttgaagc
    24961 atgtagaggc ccctaccttg ctgattaccg gaaatcagca ttcagaaatg gccaaacagg
    25021 ctgatatgtg tcttgttata tcgcaggagg aatatgattt tgctaaagta gcgactttct
    25081 cctctcaaat tgccttcgat tacgtattaa atacgttatt ctcagtgata tattctcaaa
    25141 attttgaaga gaatatccgc aacttgaaaa acaaacaaga attgatgcaa aaaggccttc
    25201 ttaaagaata tcggaaaact taagaaaaga tcctcattta gtaataagaa agatagtgtt
    25261 tgataggctc tctttgatat catcataaaa acaggctgaa gttttctttt tcaaacctca
    25321 gcctgtttgt ttacggaacg attcgaatag atatattata gaaatgagga atagctaact
    25381 tctgtttctt attttgaacg attgacgaaa aagatatata agaaggagga aaatcagtat
    25441 acatgcagct aacaatccat acaggaaaaa tcgtttgttc tcggatactt tctgtacttc
    25501 tttttgaact tcttttgcat gataaggaac ccggtgccct ctgacaagta agcgatgact
    25561 gttgaccata taaggtgtac aagttaggag tgtcacgaaa tcctgccctt tttcgattct
    25621 cagatctttt gtatcagtcg gttctaccgt cttgatctga tcgacttgat aagcgagtgt
    25681 ccgtccattg atttcgatat agaaagaatc acctaaagtc agtttcggta agtctgtgaa
    25741 caactttgct tgaggcagtc ctcgatggct ggaaataacg gcatgtgtat tttctccccc
    25801 cgtaggataa gacgttcctt ccaataatga ggcacctttt tctagcagca cagtattcgt
    25861 ttcatcaaaa attggcaaat ggacattgat ctcagggatc gtcaaaatac cgatcgtatg
    25921 tttctcaaaa taggttctat cctttttcgc aggttctttt ttcttagtaa agggatctgc
    25981 acctggattt ccaccttctt ttgctaattg ctggtttttc tttgtcatgt tttcttggat
    26041 tttagccatg acttcttcat tttctttgac cgcttgttgc tgataatgag agatgatctg
    26101 ctgatccaga taattattca gcgcgtcgct aacaaatgga taagctagta tccctattcc
    26161 tgagagaagc aagaaaagca tcagcagatc tagaagtttc cttttctttg gtttcatttg
    26221 tgttctcctt gtgatgactg tttgataata aaagaaaaag gagcatttgc gtaatccgct
    26281 gctccttttt ccaattcttg caaaaagact aaatctgact gtgcttgcgt ctagcaaagt
    26341 acagtccagc aatcagtaga aggactactc ctgcaccgat atacacatag attcccttac
    26401 cgcctgttga aggaagtgta cctttgtgtt tatttggtat tttttcagga gaaatcaact
    26461 gtcctgctgt tacataagat tgttcatcga tagtaaatgc tacacggttt gttaatggaa
    26521 catatttttc tggcgctttc gtttcttcca gatagtacgt gccatatttt agacctgtca
    26581 catcgattaa accgttactt gtggttgtaa aaaccgttgc tgattctttc gccgataccc
    26641 agctgacggc ttttgtggat gggtcgatcg ataaatattt cgctgtgtca ctatcttgat
    26701 cacgaacgac gaattctgct ccagcaagtg tttggtctga tgtaacgtca ccatctactt
    26761 taacaaatcg tttgccccca gtaacgacat cgactgacgg tggtgtttga tcatttgtat
    26821 gcccgttatc gacatttgct tggttagaaa atcctttggt tggatctgct ttttcgttca
    26881 aatgcatata gtaaacgaat ttcaatgtac cgccaggagt taatgaagga atataattcg
    26941 gatcaactga aaccgtgaat ccgtctgttt gctcagtgac agaataattt actgggtcga
    27001 tttctttatt tccatcatat aaggcataag catacgttcc tgaagaatca ttatcaaatg
    27061 ttaaagcagc gtcatgagta tcgataagtt tgaatgttgt gtacttgttt tgcgttcctt
    27121 ctttatcagc gatacctaat gggatattga cagaaatctc atattgaatt ttttcaccga
    27181 ttgcgacatc ttttccattc aattgaggtg ttgttttatc aactttagac gtatcatttt
    27241 tgatggtctt ttctactggt gtttggctat ttgccaggat ctcaaaaggc gtgattgttt
    27301 gcttttcaat catttccgca ttatcaggag cttttacttc ttctaaatta tattttccaa
    27361 cttctaaatg attaacgatc aactggcctt tttcaataga tgcctcggca aagtcattgt
    27421 tgccgatgtc ataagaatga ccagtaatga aatgtttggc tttggtttga tcagttgtcc
    27481 aagtgtacaa tccatctgtg acactttgga tgtatttttt gacgcttggt gttccttctt
    27541 ctttagaaat aataaattct gctccattta gtgcttcgtt ttcggcagta ccgatttttg
    27601 taactttcaa cgttccatca ttaccgactg tatttttagg gtagagatgg atagtatcta
    27661 gttcttctgt cccgtattta taagagccat ctgcttgttt gatcatctca tatacaggga
    27721 aagctaaaac catgtttgcg gcagctgaca ctccgtcttt tggttcttct ttgatcgtgt
    27781 agactgcatc tttcccattt tgttttttag gtaaagataa agtgacattt ccatcagcat
    27841 ctgtcgttcc tgaagcaact ggtgtaccag gagtcaaaga ctggactgct tgttttgctg
    27901 catccacgga cgctccttta tctcgttgcg cataaaattc ttgagtgacg ttataaactg
    27961 aaaatgaaat atcggctaat ccttggtatt gatcgaattc gctcatttct ttcccgctgt
    28021 tttggattaa aggatcgggt aaatcagtca ttttcttttt atgaaggatg acttgagctg
    28081 ctgtctcctc tgcaaacact ttttttgcgc cgaagctgtt tgtgagtaat ggtaaaataa
    28141 ggaaaaggac tcctaacata acgtttattt ttttatgatt tttcattttt tcactcctgt
    28201 tctttttttg ataaacaacc agattgcaaa gcttgcgaat accataccaa caacgcctaa
    28261 aagtgtattt ttcgtttcgt ttgtttttgg aagaaatgga cggctatttt cttttttatt
    28321 gactactttc aatatactgt ccgcctcttt atcctcagaa agaaaagttg aaatggtaaa
    28381 cggaatttct gtttcactta aaatataacc agaaggtgct tcgatctctt ttaatcgata
    28441 acttcctgtt ttcaacccgg aaattgaaaa agcgccattt ttatcggaaa tcaggtgaag
    28501 cgcatctgat tcgttctttg tccacttgta tccgttggct gtttgctgga ggtaatttcc
    28561 tgctttgttt ttaataagga atactgcgcc agctaatcgt ttatctggtt tatttgtctc
    28621 gattttgaca aattgcttac tccctgtata tacagagact ttctttgtac tgacaccaaa
    28681 accaaaatcc agtgttccgt tgttgttgat ttccttgttc gcctgtgctg tactgcttag
    28741 ctgcatctga taagaaatgg tcagtttttt tccagcatat ttttccaacg aagggatcga
    28801 aaataaaaca tcaaatccgt gaggtttctt gtgtatgaca aagccttctg tcagcttttc
    28861 tccattcgat gaaatcgtta aactattagg taaaaacgtt aatgcttcat ccgcactatc
    28921 tgacaattcg aacttttgat agtcaaggat atttacagga attgtcgtat gcaaggaata
    28981 agtgattttt tcaccaatcg taaaatcatt tctaggctct tctaatacct tctcaaaagg
    29041 tggatcaggg tagtcgtttt cttcattttt aggatacaaa tggatagttg aaagtttttg
    29101 attgttttgt ccatgtacag gaagaacaac taccatattc tctgcctttt ctttgacgac
    29161 ttctggtact ttggattcaa tgaaaagata cgctttatct cttttttctt gatctttagc
    29221 ggccagagaa aaagaagcga taccatcttc gttgttaaga gttgtagttg ttgcttctgc
    29281 ggtaaacata ccggaagacg caccgttttt tgcgatctct gcttgtgctt cttctaccgt
    29341 tttgcccttt tcccgtagat ggtaaaaaga atctgtgaca tcataaactt ggaatgtgac
    29401 accatttaat cctcgatacg tttgtaataa agctttttct tgtccgtcat ttggatgatt
    29461 tttcggcagt tgcccgtttg ggaaaagcaa tttgtgtaaa gtaatctgaa ccatttctgt
    29521 ttctgtttct gttgctacct gagtaaaagc tggtttaaat agtaacaaga agagacacat
    29581 actaagccaa ccaagttttt tcatatttag ctgccccctc tttctttttt caaaaaaaga
    29641 taccaaatag aaaacgcaca accaatcatc cctactagat agattcctaa acggccaatt
    29701 cctcccgttt caggtaatgg tacttttgcc tgattcgtga tgtctaaaga aatctggttg
    29761 tttttggctc ctggtgacag aacagattca tgatcttgtc catccacttg aattgaccca
    29821 tcttcgtgta taactatagt aactggctct tttagacctt ggtatccttc tggtgtaaaa
    29881 gtttcggtca gcgtataagt tccaggtttt aaattttcga atagaaaggt atctgtttct
    29941 tgtccatctt ttggcgattc taagtccatt tctggtccct gcagtctgaa ttttgctcct
    30001 tttaatgtct gtccgttgtc ttcttttttg tgtaccgtta gatcaaacgc ttttagtcga
    30061 ttttgatgag tgagcgtcca tacattattt gtcatctcgg tattttttcc cgtgtaaatg
    30121 atttttccat atttatcgat ttggaattca taatttcccg gcgaagtatc atatccggca
    30181 ggaccagctg tttcaacgac tcgatattta ccaggtgtga gtgaatcaaa actggcaaga
    30241 cctttttcat tcgttgtttg gctgtcaatt ggctgataag taccatttgc ttcttttttc
    30301 tgtagggaaa atgctgctcc tttaagattt atctctttgt ccgtcccttg catcgcatac
    30361 ttacgtactg ctacaggaac ttcaacaaaa ggattttcaa tagtcaactg gatcgtatca
    30421 tcggaagtag tgactgtttt tccatcaatg gttaccgtac catcagaagc gatcttgatt
    30481 tcccaagtag tctttttgct taatccatgc ccttctggag cttttgtttc tgtcagcgta
    30541 taggtcattt ctttttgcaa tttgacattt tctggaagag aataggttcc gtcgccatga
    30601 tctgttagta aagtatcaat agaatctcct gttaatttga aaacagcgcc aataagatcc
    30661 ttttcacctg tagaggaatt tttcgttatt ttcaagttta acggtgtgaa ttgtttagta
    30721 tttttccatg tcattgcatc tatttgttga gaatcgtatc ctggtacagg taattctttg
    30781 attgtttggt aactgaatgc ttgaccttga ttattgtatt gaggtagtga taatatctct
    30841 tgataacttt ctccgctatt tgcagataat ttgtcaatgt ctgcacgttc ccacgtattt
    30901 gttgtatctt tagctggttt aatgattcga atatatccgt ttttccaagc tgcagcattt
    30961 gtcgtatgtt cccgttgaat ctcaaaagta acttgatctg gacgatcagc tagattgttg
    31021 tcaaattctt cccataactt tttgatgtga agactgactc cgggagcttt agcagatggt
    31081 ataccgaatt cagctaattc attggtatca atgtttggct ggaaagttgt cctgccgttc
    31141 atttgatacc agaaatttgg atggaagtcc tcattttctg tttggattct cacttggtaa
    31201 tggatttgga tttcttggtc ttttcctaaa tagatctgat tgctcttgat ggtatttcct
    31261 tctatggaaa tagatggagt gaccgttgta ggacttgtcc ccacactctt gactgaaagt
    31321 gtaccaggct gataaatgaa tggttctgcg attggatcat ttatttgtcc attgcttaca
    31381 gttgctgaga tctgtacagc ttttttggct aggtattcag agatatctgt tgcatgatca
    31441 gctgattcat agtaaagatc gcctttttca tctgatgaaa ccatttgtcg catacgagac
    31501 tctacttctg cttttgagag accagctgcc ggatcgcttt gaagttggat gccaagacca
    31561 tgtatttcga ttcctcgttc tttgagtgcc atcgcttctc cgatggttgc gataaacgta
    31621 ctgtcgattc ttctggatag attgttttgg tcaggtgcat catagattct tgagattaga
    31681 gaagtatttc ccggccgatc ttgcgtatta gaaaactgag ttccgtaata attgctgctt
    31741 gattgtgcgt gtacccgctg tactttatag gaaaatgttg gtacaccatc cgtcagcaaa
    31801 acgatcactt ttttatgtcc atttggaacg gatagcatgc ttcctgcatc tcttagtgct
    31861 ttttgtgtaa aagtaccacc atttgtccgt gaaggtgtaa tggattttac ttgatttttc
    31921 actgaatcaa atgaacccat ctgtactgca ccgttactgt agctatatcc ttcgcttgag
    31981 tagccgacat atcccatatt gattttgtct gtgataccgc tatctgctaa agtatcgaca
    32041 aaacgatcga caccaatctt tacttcaccg atccgattat tgtcgttcat acttcctgac
    32101 cagtctacga ccaatacgag atcaagaggc gtgatatctt tttgtacatt tccacgagca
    32161 ttcaaataaa catcaaacaa tccgggtgta cttgtttcct ttgcatactt tcgtatcgca
    32221 tagtctgctt gattaccggt tcctccatat tcgatatacg aatgggtccg atcattagga
    32281 tctccattcc aagaatttat accatcccat tgatttgttc cgtttttatt gccttgatga
    32341 tcaagaacat ttgtatttcc tgtaggttgc caactggctt taggataagt gccctgatca
    32401 tctgttgtat attctgtagg aatcgtttga ttagatggca cactcacagc tggcaaggat
    32461 aatgtaggca atgtaaatgg gctgacagaa ttttcgtttt cttttgatga ttcttcttct
    32521 atttcgtctg gctttggtac tgacacatct gtatctttct tattttctgt ctcatcaata
    32581 atgtcatatt ctttattatc gacgatcagc ttgtttgcct ggctgtggta aagtgctgga
    32641 tcgattggaa aactcagatc gatagtttgt ttagtgtttg atgagatttc caacgtaatt
    32701 ttcccgctat ttacctgata agcatagcca tctccttctt ttctttccac atcacttaag
    32761 taattttcga ctagaccaat ttctttttct atcttttcag cactggtgtt attcgcattt
    32821 agcttgatgt tcagtgcttt ttttccagac tgatccgaaa tgacttcagc tgaaattgtt
    32881 tctaaaactg ttggatcatc tgtagtgtct gctattgcag ataatggcac aaagtttgat
    32941 aaactcaata ttatcagcat gaaaataact ttcagtttct tccctgtggt cgtcattttt
    33001 cccctccttt ttcttttttt ctgttttgac gtgaatagtg aaaattatta aaataaacag
    33061 gcgttacata attttattta ttttaatatg ataattatta tacgaagggc gctaaaggga
    33121 atcacaccaa ttttcatacc aattggtttc atttatgaag ttgattcctt cgattaatga
    33181 gcgtttcatt gaaagaaaag ggttgaggga gaaaaacata tgatcaggtt gttggaacga
    33241 aactatagaa agatggaaaa aatcattcga attctgtcca tttctgacaa gtggatgact
    33301 aaaaaagaac ttgccaaacg aattggtagt tcagaatcta catttgtaag gtatatcgaa
    33361 gagatcaaaa tccgctgggg aacggatgta acgattcaat cttcacaaaa attggggtat
    33421 cgtcttgaac atttgaatgt accagcttat ttaaatgttc tgatggaaat gtcgcaaagt
    33481 tctacaaaca gtcgtttatt aaatgagatt attgtcaatc cgggtaaaac gattgagtat
    33541 tattgtgaaa aaatttccat cagccggtct tcttttacac gtaagttgaa acaatgcaat
    33601 caaattttag aaagctattt attaaaagtg atcgttgacc aaggttttca gttaactagc
    33661 cttaaaagtg agctccagtt gcgtatcttt gttacctttt tctttttaag ttactacgga
    33721 agacgcacgt tgccatttcc aatcgaaaaa aagaagatca aagaaattat ggtcaagaat
    33781 aattgtcaga tgaatttgtt tcaggaagaa agcccatatg agcaatcttt ctttattatg
    33841 tattttgttg tgcatctcat gagagaatcc caaggaactc catttgaatg gaaagctgga
    33901 gactcttatg tacagttgat aaatatcgat aaaaaagact tcttaatctt gaaaaatctc
    33961 ttaggaaaat tgaagtacag cagctatata aaagtagtga actattttgt caatacgatt
    34021 ttttcagaat tttcggagaa agaaaaaaat gaaatcagtg agcagatacg aaaaaatatg
    34081 tcctactgtt cgttttcatc cgctgattgc aaagaaaaaa acgaagaata tgttgttcaa
    34141 ttattaacgc aaatttattt tttctcccgt attttcccat acgatacgac tcatttgacg
    34201 atccgtgcaa cttactttgc acagcagatg caacaccgcc agatacgtct atatgctgga
    34261 tttcgtgcag aacttcaatt ttattccact ctactgaatc agaatctgat ttattattta
    34321 tctagctata tcttttggat gcttatcggt aatcctgaaa ttcaccatta tacttctgat
    34381 aaaaaaatac tgattatcag cgacttaagt cttcgacata gtcaatatat tgaagaatat
    34441 atcagtgata ttcttgctgt gcataaaatt cactctgaga caactgctat tactgaagat
    34501 cagctgtcga aatacaatct tctcgagtat gatctgatcg ttacgaatca acccattttg
    34561 aatgcccatg ttcctcatat attgattgat gatagtgtgt cattcgcaaa tgaagaagaa
    34621 ctcatccgct tattcgagtt atgaataatc aaaaaacagc tatgtataaa ccaccctgat
    34681 aaaaatttca ggacaaatac acatagctgt ttctttttat tgtattcctt cagcaatcca
    34741 acgagattta tagcgaaagt cttttaacaa ctcttctttt gtccaattat ttgcaatgag
    34801 atccgtcaaa gtgttcatta cgagggtcat ggaaaagtat aggaaactaa ctgcttcttc
    34861 cgacgattga atggagaaat gattgattct taataattcc agccattttt cgttcattgg
    34921 agaatcagcc gatagttctc tacgtttggt tgtctgctga tcatttcgct gggttaacaa
    34981 gtataacctt tgccaataga tactttcgtg atctaagtcg cagcaccact ctaaatattt
    35041 ttcgatcccc aaaaagaaat gttgtttgtt ttcgctaatg aattttaaga tatcttgatg
    35101 gactatgtga gaactgcttt tgatcgtata caaataagca tcttccaaat cttgaaaata
    35161 tttataaaaa gcaccgcgcg acatccccat cttgtcaacg atttctgaga ctttgacttg
    35221 gctgatgtgc tgtgagcaaa atatctccag taataggtca tcgattctct gtttctttgc
    35281 gttcgataaa ttgaaaaaag tttcttttgg catccacatc tctcctttat ctctgattat
    35341 acgtggatag cccttcattg tcatgaagga ttcattcctt ctttttctct tcttctgtca
    35401 agtacccatc ttccattcga taaacgcgat cactccattg aatcatacgg acatcatgag
    35461 taaccataat agtcgctttt tgtttctcat gagcttcttt aactagtaat ttgacgactt
    35521 catatgcatg atctgtatcc aaactagctg ttggttcgtc tgctaagatc aagcttggct
    35581 cattatataa agcgcgagca attgccactc tctgtctttc tccaccagaa aggtctttag
    35641 gataactatt tttaagtgac tggatatcta aagattgcag caaggaatcg atttttgttg
    35701 aatcttcttt ttttgaagta acttggtcaa ctagttcaaa ttgttccttt accgttaaaa
    35761 aaggaatcaa attagagctt tggagaataa atcctatttc tttaaagcgt aaatctgctc
    35821 gttttttttc tggaagctca gttagtgagt gaccgttgat cactatttct ccggaagtcg
    35881 gtgtttgcaa tcctcctgaa atggtaagga aagtactttt acctgaacca gaaggaccaa
    35941 tgatgctgac gaattctcct tcctttacat aaaaatcaat tgctttcaaa gctgagacct
    36001 ttgtatgacc agaaccaaat gttttggtaa cttttttcat cgttaatatt tttttcattt
    36061 ttattaacct cctattgctg taattgggtc tactttggtt atcgtacgta tcgaaaacaa
    36121 tccgcctagc attgcgacaa tgatcaaaat cccactatat agcaaccatt gtgaccaaaa
    36181 aacagcaaaa ggcatcgcgc ttggtaaaat cagactagtc aaataagcaa acaaaagagc
    36241 aagcagaacg cctaccaccc caacaataaa ggactgtgct actaaagatt tagcgatgaa
    36301 gaaatttttg atcccttgtg ctttcattac tccaaaaata gcagtcttct gaagtgtcat
    36361 cacgtacatg aaaataccga ccacggcagc aaccactaag aacaaaaagt atatcatcgc
    36421 atttaaggtc atattttggg cagaatagcc aggaatactt tcaatgaatg tcccaatagt
    36481 taataactgt agacccttcg atgctttttc tttcgaaatt ttagctgaat cctttattac
    36541 gatcccattg atcggctgtt cttcttcaga agcaaacggc tgttgtccat acttcaaagc
    36601 agtccacgta tctagggacg catagatgac gggagaaact gtgtaataag tttcaggaaa
    36661 gataccgaca atcgtcaaag gatcgtcgta actgccaatt ttgatcgtat ctccaatttt
    36721 atagcctgaa tcagccagat tttgagagat gatgatttca ttctttgttt taaattcatg
    36781 ccctttcgtg agttttggta ataaaaatgc ttctttcgtt gtgccgaaaa ctgtaacatt
    36841 ttctttgttt tttcctttga ttgctccgct gtacaatccg attggtgctt tctctcctcc
    36901 ttcaatgtat ttcagatctc ctcttgttaa ttgtgaagct gcaaatactt gatttgcatc
    36961 ctccgacaaa acaatctctt gtgcgtccca atcatcgatt gcttttttaa actcttctga
    37021 aagtccattc gctagtcctg acaacatgaa tacgacatac gcaatcaaga acataatacc
    37081 gacgatcaag ccatatcgta atttagaata gcgaatttct ttgatagcta gaaacatttg
    37141 tttttcctcc ctatgataga ttgatagtga caaaatgtca cttgttgaat agtgtaactc
    37201 taaagtgaca atttgtcact tgtgttgttt ttttcttatc aataaattgt ctaagacatc
    37261 tttcgataaa accttaacat gagtcataaa aaatttattt aagccttatt tatgctttcc
    37321 atgataaact aaagtgacca aatcaatgag gtgggaaaat gattaaacta ttagtagtag
    37381 aagacgataa agtattatcc aataatataa aagaaatact cgctgcaatc ggcgagataa
    37441 cacaagttta tgatggtagt gaaggactgt tcgagttgga aagtggagtt tatgatcttg
    37501 caatcttgga tttgatgatg ccggaaatga atggatatga agtgttagca aaaatacgga
    37561 aagaaaaaat acagactcca gtattgattt tgactgcaaa agatagtttg gaagataaga
    37621 ttgaaggatt tgaacgaggt gcagatgatt atctaacaaa acctttctat cgagaagaac
    37681 tgatcatgcg cgtgaaagca ttattgaaac gctcgctagg tctctttgat gaaaatgttc
    37741 tgaagtataa ggatatcagt tgtgatttaa aaagcaatga agtcttgtat aaagaacaag
    37801 ttttgcccat acaaggaaaa gagtttgaat tgctcgttta ttttttacaa aataagggaa
    37861 tcattttgac aaaagagcag atatttgacc ggatctgggg atttgattct gatacgacga
    37921 ttacagttat tgaagtttat atgagcaact tacgaaaaca tctgcgaagt actggattgg
    37981 ataaagaaat caaaacctta cgtaatgtcg gttatatact gcaaagggtg tgatgcaatg
    38041 aatggagata ttacacgaaa gcaacgtagt cgcttttttg cgacaaatgt agcagcattt
    38101 gcttttatct tttttctttt gggattcatt actttacaga tattaaacca atctgcatac
    38161 agagaaacag atctgtcatt agagaaaata aattttgatt ctcgaacagt acaattagag
    38221 atacaaagat atcagcaagg cgatcccttt ttaaacccga ctcaaacgga acaaaacaga
    38281 acaaacatgg aacagccatt aatggaacca tcaaatgacc gttttaacac tcaagtgatc
    38341 ttgtggtcta aaaatggtga gatattgaat aaagcagcta ttggtgggcg tttcaaccaa
    38401 atcaaagaat taaaaatgga tacgaaaaat ctgaatacca tccaaaatat tgaattaaat
    38461 gaagacagtg gctcatctgc cctctctttc cgttcgatta cgaaaaaagc ggagacgaat
    38521 caagatggcg ttgcctacat ccaaatttta gaaaatacaa atcaaatcaa gaattcatta
    38581 gcgacttttc gcacgattat gattttgtgt atgattgttt tttggattct ctctattggt
    38641 atcagttatt acttgtctag tctaagcatg cgccctatta ttctttcttg gagaagacaa
    38701 aaagaatttg ttgagaatgc ttctcatgaa ttgcgcacac cgttaacgat tattcaaaat
    38761 agtttggaac atctttttac caagcctaat catactatta ttgaagaatc cgaaagcatc
    38821 gctcaagcat tgtcagagac gaggcgcctc actggattga cttcggattt gctgacaatc
    38881 gctcggaatg attctgatca gcagctgctt tcaaagcaaa tgatcaatac acaagaatat
    38941 atcgaacaac ttgttaaacc atttcaagag atggccatca tagatggaaa agagtttatt
    39001 ctccataacg atgcaacatt agaagtacca attgatgaaa aaaaaatcca tcaagttttg
    39061 gttattttgc tggataatgc attaaaatat acgaatccag aagataagat cattttggat
    39121 tcatctgtta accataaaga atggctgatt cacgtaaaga atactggccc ttctatcagt
    39181 gaagaagatc aagcaaggat ttttgatcga ttttatcggg aagatcaatc tcgggcgaaa
    39241 gagactggcg gatacgggct tggcttggca attgcaaaac aggtaatcga acagcatcat
    39301 ggacagattt ctgtatccaa ttatcttcca caaggagtcg attttaaagt ccaattgccg
    39361 ttgaagccta aaaaataatg cttatcccta aaaaagggct gtgacaaaaa tcttgtcaca
    39421 gccctttttt gttgcgaata aacggtgttc cagaagtagc ttcttcggaa ataagccgaa
    39481 atttctttaa gctgaccact tctgtcacaa cctctttagc ttacgcttac gattttttat
    39541 tgcggtcttc aatgtgtaca tcaccgcttg tgtcaatatc caattcttct cggctaacat
    39601 cttctgtcac tttttcaaca tcttcatgtt cttctttatg aatcccaact tcttcacgaa
    39661 taactgtatg tttgcttaca tctacttgct cttctttgat tgggatagta atcgtgtcat
    39721 cttccaattt ttcgtctgtt ccctgtgaag attgatctgt tactggtttg cgttcgatga
    39781 cgatttcttc acgtttgacc ggtacttcta ccgtttcagt atcgttgacc acatgtttgt
    39841 ggatgtcgac ttctccagtt gtcacatcat gtgtatttac atctaatttt tcttctttta
    39901 gttgaattgt atcatcatct agatttggtt tgcgatcgat gtcttcagtc ttgcttgtac
    39961 ccattgtatc agtctcgcca ggtacgtcca tcggatcagt tcctggtgtc atattcaatg
    40021 gatccgttgt attttgaaag cctgtcgtgc cacctacgtc cattggatct gttccagtgc
    40081 cagtttctaa tccagtcccc attgtgcttg ctgggctaac agtatcttgt gtatccattg
    40141 tatcttctgt tgtttctggc tgacgatagc cttttactgt gatgacaaat tttccatcag
    40201 aaatatctcc tctatattga tataaaggat cattttctgg tgtagccgtc tcagaatcat
    40261 aggtatcaaa agaaaaagta tcttttattt tttcccataa agaacggtct tcttcaccat
    40321 ccatccgatt ttcatctgtt tcaacatcta taccagacaa tccgtcaaat cctagtctag
    40381 atgctgcttc atcagtagta taaataacga tatcatctcg ttcataccct tcgttacgca
    40441 accgttcaat tactgataat gcttcttccc tcgtactata gcttccgatg accgttaaat
    40501 ttttctcttc catgtaaatt cctcctagca aatagattta tgattggtat attgttactt
    40561 ataaatttat tctataggag acgattgttt tctacaaata tttagattgg aatttgatta
    40621 aaacaattta attgaaattt gaaaacattt atgttaatga aagtcatatt ctaataaaat
    40681 gtcatttgtt tctatatgaa tttttatgaa aaatttcata taatttccac tcgttgtgat
    40741 ggtttaattt atccaatcca tcaataagca aacaacttat ataaaaaagg attaattctc
    40801 aatataattg ctcctaccat agaataaatc ttcatgtaaa gtaatgaagt accaactatt
    40861 tctaatactt ctttaagaat tatcccaaca atatcgttag acaaaccatt attgaataaa
    40921 tggagagcca atcgattctg aaaaaatgtt ttctaatttt tcggaaataa aagaaagagc
    40981 ctcctgccat tagaacgaac caaatccatt tcattgctca tgaagtaacc acatagctaa
    41041 aaagaggata aatcaattaa aagatcaaaa gaatgactgc actaataaaa taactaaaaa
    41101 tgtatcttct tacttcatat cttttagcta gtacttagtt aaaaatttgc ttcctaagat
    41161 caagacaaac tgtctatctt catttgatga aatgcggtaa aatatagaaa atgaacacta
    41221 ttggagggaa tttgtaatgg acagcaaaac tagaaaacaa ctgcaagaaa agttaaagca
    41281 acgtacacac ttgctccctt ccgtctttca acagttttta gaagaaaatc gttcttccct
    41341 ttcattaggc agtcgctatg aatacgcaaa agattttcat ctgtttactg attatttgag
    41401 aaaagtattt tctgaagaag tggatgatca gctgattatc catttagaaa aacaagatta
    41461 tcagaatttc ttagctaaaa tctatcgaca tactcgttcg ttccaaacta cagcgaacca
    41521 agaaacggag caattgtttg aaaatagcta ttacgggatt tcaaggaagc aatattcatt
    41581 aaatcatttt ttacgatttt tgtatcaaaa aggactgatt gaagaagaga tttctctttt
    41641 gggtacaagt ttaccggaaa caaccaaagc agctccgcga tatatcgatg cagaactttt
    41701 caaagatttt gagcatttgt ttatcccgat tgaaggcttt caaacaagca gagaagctag
    41761 ctttgaagaa aagaatagac cgaggaacct tgcaattact gccattcttc tgtattgcgg
    41821 attaaagatc catgaagtag tagaacttaa acgtaaagat gtatctttga ccaagcagat
    41881 tcttaatctg aatagaaaag aaaacagact gaataaagta ccaataccaa aagaagcgat
    41941 gccatttctg gagaactatt ttaagttaac agcacaaaat acggacgaaa attcttttgt
    42001 ttttcgttcc tcacatgatc agcaaatttc tcctcggact attcgccaaa ttttgagcaa
    42061 aattacagta tataaaaacg tatcgccaga actatgcaga aaaacatatc gttattatgc
    42121 agaactatat ttagatgatg ctgacgcggt aaattattta tgtggtaatc gatacctctc
    42181 atcccattct tttcaagata tctgggaaaa gatggttgat ttttcttatc acgaattagc
    42241 ggcattcgtt cgggtttctt ccatataaaa caaatgtatg atcttttttt cacaataaac
    42301 tatgttatta tataaaggat tatgttacga ttatcttgaa tttgtatatt acttaacaaa
    42361 agataatgga gtgtgaatga tggagaccat aacgtattcc cctttgaact tatttacgaa
    42421 ttttcaagaa gctgcagcta acttttccga gaccccgatt atctttgatg agccactttc
    42481 agctttccca gaattaggac ttgaaacaac ttacaaaaaa tgctgcgaaa gtgtgttgaa
    42541 acgggcttat caattggctc atcttggagt gaaatccgga gacaaagtta ttatttataa
    42601 gagttccgct tttgacacat accttctagc tgtttctgtg tcttaccttg gtgcagtgcc
    42661 tgtcatgact tcttatcatc taccaacaac aacaatggaa gtatttatcg atcgtttaga
    42721 agaccctttc attttatttg atgatgagac aaaaaagcga gtgagagaaa tttcaaatgg
    42781 aacaaaatca aaacagattc
//
LOCUS       DACBZK010000016        41132 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.016, whole genome shotgun sequence.
ACCESSION   DACBZK010000016 DACBZK010000000
VERSION     DACBZK010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41132
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.016"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(79..1338)
                     /locus_tag="IVD66_000938"
     CDS             complement(79..1338)
                     /locus_tag="IVD66_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP6145182.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            complement(1440..3206)
                     /locus_tag="IVD66_000939"
     CDS             complement(1440..3206)
                     /locus_tag="IVD66_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HAP6145183.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            3595..4443
                     /locus_tag="IVD66_000940"
     CDS             3595..4443
                     /locus_tag="IVD66_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP6145184.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            4543..4977
                     /locus_tag="IVD66_000941"
     CDS             4543..4977
                     /locus_tag="IVD66_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP6145185.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            5157..5567
                     /locus_tag="IVD66_000942"
     CDS             5157..5567
                     /locus_tag="IVD66_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAP6145186.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            5624..6064
                     /locus_tag="IVD66_000943"
     CDS             5624..6064
                     /locus_tag="IVD66_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP6145187.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            6167..7246
                     /locus_tag="IVD66_000944"
     CDS             6167..7246
                     /locus_tag="IVD66_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP6145188.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(7372..8513)
                     /locus_tag="IVD66_000945"
                     /pseudo
     CDS             complement(7372..8513)
                     /locus_tag="IVD66_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            8661..10214
                     /locus_tag="IVD66_000946"
                     /pseudo
     CDS             8661..10214
                     /locus_tag="IVD66_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
     gene            complement(10322..11404)
                     /gene="uxuA"
                     /locus_tag="IVD66_000947"
     CDS             complement(10322..11404)
                     /gene="uxuA"
                     /locus_tag="IVD66_000947"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAP6145189.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(11395..13041)
                     /locus_tag="IVD66_000948"
     CDS             complement(11395..13041)
                     /locus_tag="IVD66_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAP6145190.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            13225..13887
                     /locus_tag="IVD66_000949"
     CDS             13225..13887
                     /locus_tag="IVD66_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6145191.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            14031..14594
                     /gene="ahpC"
                     /locus_tag="IVD66_000950"
     CDS             14031..14594
                     /gene="ahpC"
                     /locus_tag="IVD66_000950"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003756453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HAP6145192.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            14604..16133
                     /gene="ahpF"
                     /locus_tag="IVD66_000951"
     CDS             14604..16133
                     /gene="ahpF"
                     /locus_tag="IVD66_000951"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HAP6145193.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            16290..16640
                     /locus_tag="IVD66_000952"
     CDS             16290..16640
                     /locus_tag="IVD66_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HAP6145194.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            16739..17269
                     /locus_tag="IVD66_000953"
     CDS             16739..17269
                     /locus_tag="IVD66_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145195.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            17423..18574
                     /locus_tag="IVD66_000954"
     CDS             17423..18574
                     /locus_tag="IVD66_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAP6145196.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(18683..20722)
                     /locus_tag="IVD66_000955"
     CDS             complement(18683..20722)
                     /locus_tag="IVD66_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HAP6145197.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQATRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(20780..21535)
                     /locus_tag="IVD66_000956"
     CDS             complement(20780..21535)
                     /locus_tag="IVD66_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAP6145198.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            complement(21627..22757)
                     /locus_tag="IVD66_000957"
     CDS             complement(21627..22757)
                     /locus_tag="IVD66_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP6145199.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            complement(23298..23504)
                     /locus_tag="IVD66_000958"
     CDS             complement(23298..23504)
                     /locus_tag="IVD66_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145200.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(23520..24134)
                     /locus_tag="IVD66_000959"
     CDS             complement(23520..24134)
                     /locus_tag="IVD66_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAP6145201.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(24281..24964)
                     /locus_tag="IVD66_000960"
     CDS             complement(24281..24964)
                     /locus_tag="IVD66_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAP6145202.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(25073..25531)
                     /locus_tag="IVD66_000961"
     CDS             complement(25073..25531)
                     /locus_tag="IVD66_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HAP6145203.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(25615..27378)
                     /locus_tag="IVD66_000962"
     CDS             complement(25615..27378)
                     /locus_tag="IVD66_000962"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HAP6145204.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(27599..29059)
                     /locus_tag="IVD66_000963"
     CDS             complement(27599..29059)
                     /locus_tag="IVD66_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145205.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(29267..30193)
                     /gene="glsA"
                     /locus_tag="IVD66_000964"
     CDS             complement(29267..30193)
                     /gene="glsA"
                     /locus_tag="IVD66_000964"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HAP6145206.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(30216..31427)
                     /locus_tag="IVD66_000965"
                     /pseudo
     CDS             complement(30216..31427)
                     /locus_tag="IVD66_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            complement(31462..33075)
                     /locus_tag="IVD66_000966"
     CDS             complement(31462..33075)
                     /locus_tag="IVD66_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4368 domain-containing protein"
                     /protein_id="HAP6145207.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            complement(33187..33396)
                     /locus_tag="IVD66_000967"
     CDS             complement(33187..33396)
                     /locus_tag="IVD66_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HAP6145208.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            33487..33675
                     /locus_tag="IVD66_000968"
     CDS             33487..33675
                     /locus_tag="IVD66_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145209.1"
                     /translation="MAVREYHYLTVQVMAIKEDKSFTRTQIGFRSLLQGKGRGVFVST
                     ASCLSNVLNSFIQLSKND"
     gene            complement(34385..35599)
                     /locus_tag="IVD66_000969"
     CDS             complement(34385..35599)
                     /locus_tag="IVD66_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP6145210.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQP
                     LNDELREIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDY
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKEKYKAGECMSYFRMQKDYSGTEKCGSDLPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTAVPQENDGIF"
     gene            complement(35727..36197)
                     /locus_tag="IVD66_000970"
     CDS             complement(35727..36197)
                     /locus_tag="IVD66_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP6145211.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            complement(36194..36436)
                     /locus_tag="IVD66_000971"
     CDS             complement(36194..36436)
                     /locus_tag="IVD66_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HAP6145212.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            complement(36982..37512)
                     /locus_tag="IVD66_000972"
     CDS             complement(36982..37512)
                     /locus_tag="IVD66_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP6145213.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQETGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            complement(37694..38350)
                     /locus_tag="IVD66_000973"
     CDS             complement(37694..38350)
                     /locus_tag="IVD66_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005603505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HAP6145214.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            complement(38477..38950)
                     /gene="dfrF"
                     /locus_tag="IVD66_000974"
     CDS             complement(38477..38950)
                     /gene="dfrF"
                     /locus_tag="IVD66_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HAP6145215.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            complement(39369..39587)
                     /locus_tag="IVD66_000975"
                     /pseudo
     CDS             complement(39369..39587)
                     /locus_tag="IVD66_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(39618..40832)
                     /locus_tag="IVD66_000976"
     CDS             complement(39618..40832)
                     /locus_tag="IVD66_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAP6145216.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT        11981 a         8078 c         6967 g        14106 t
ORIGIN      
        1 attttccatc tcgctcttgc cacttttatc tgaagcacct gttccatttt ttataaaaat
       61 ggacggttat cattttaatc agtatttttg ttctatggct tcactgattg tttttactgc
      121 ttcatctgcg gattcttttg gtgtttttga acctgatgct gcatcgaaca tcaagttttc
      181 tgcacctgtc caaacttcgc ccatttctgg gatgtttggc atcgcttgag ctgtttcata
      241 ttgttcaatc acagctgttg ttaattcatc gtttttagcc tttgctgttt ccctagcttg
      301 ttggtttgca gggatttcat ttaccatttc aaagaatttt tcttgatttt cctgattcgt
      361 tacataatca agccattttt gagagaggtc tttgttttta gcataattgc tgactaccca
      421 tccttttcct ccgccaaacg gttgataagg ctgtccatta tttagagtag gaattttggc
      481 tacaccataa ttgatattgt tttctttgta tgtttgcgct tgccatggac cgtcaatgat
      541 tgctgcagtt ttattggaca tgaattgctg gctggcgaag tctcctgcac tttttatgtc
      601 ttgcattccc tttggccaaa catttttgaa ccaatctgtt gcataagaga ttccttctac
      661 agcacctgca ttattcaaac cgatatctga aggatttgtg ccatcatcac caaatacata
      721 gccaccgtaa cctgcaatta aaccatagga ataataaaag tcagtccatt tagctaaaaa
      781 tcctgtattt tttcctgctt ctgactcaaa agcaaaacga ctgtctttgg atagattctc
      841 caaatcttta aacgttgatg gtgctgtatc gactaaatct ttgttatagt acaaaacaag
      901 ggtctcgatt actgcaggtt ctccgtagat ttttccatca taagtcactt gggctttgtc
      961 tgtttcatcg taagctgctt catttcccag ttttacttcc gccagatgtc cttgctgtcc
     1021 taacgcaccg atccggtcat atgctgccat cataacgtca ggtccctttc cagcaggccc
     1081 atctaacgct aatgattcca actgatcgaa catgtccttt tctactagct tgattttcac
     1141 atcgttttct ttttcgaaag tgttttttat ttcgtttata taatctttat atccagaatc
     1201 aacggaaact gttaacgttt ttccttcatc ggcttcccct tctgctgaag agttaccatt
     1261 gccacaagcc gctaatccgc ctaagattcc taaagagatt aaccctaaac ccaactgttt
     1321 cacacttctt tttttcatct tcatttcctc ctttgtattc aacgtgctgt tacaccctta
     1381 ttataatggg cacaaatctt catttgcaaa cgctttcttg ttgttaccgg taacagtttt
     1441 caacacatga tcaaaaatcc gtattgtcgt atctctgctt tcccgtcttc taacaactga
     1501 caattttgac taagaatcac ctcattttcc tgttctacta cccaaggttc ttttgactga
     1561 ttaaagtaaa catagatgat ctgtccctct agtttccgtg tgaaatagag cttatcttca
     1621 cgatcattta ctattagcca ctgagtagaa ccttcagaaa taatcttaga caactgtttc
     1681 cttagagaaa caagttcttt tataaaaccg aatagctcta gatcttgttc ctccttctcc
     1741 catatcatac atttgcggca atccgggtca tcttcaccag tcatccctat ttctgtcccg
     1801 taatagatac aaggagaccc tttttgaaga aacataaagg ccatcacaga cttcatcaat
     1861 tctttgttac cttggcaaag ggtcaagatc ctggcagtat catgagaatc taataagttg
     1921 aatgttcctt cgttcacctg atctctgtaa agcatttgct gatgattcat tccactgacc
     1981 atttgtgaag ctgtgatttt cttttttgca aaataatctt taatcgaatc tgtaaatgca
     2041 taattcatca ctgcatggaa ttcatcccct tgcagccaag cttgagagga atgccaaatc
     2101 tctccaagga tatagatgtc tggtttgatt tctgtaactg cttctctgaa ttttttccaa
     2161 aaatgatgat cgacttcatt agcaacatca agacgccatc catcaatatc gaattctttt
     2221 atccaataag ttgcgatatc cagcaaatat ttttgcactt ctggatttgc tgtatttagt
     2281 ttcggcatga atggagtaaa agcaaaagta tcatatggga tattttcagc agtttctggt
     2341 aagtcagtca tctgataaga atctactggg aaaaaacgga tgtggaacca gtctttatag
     2401 atcgattttt ctccgttttt gagaacgtct tgccactgtg gtgaatggac acccatatga
     2461 ttgaatacag catcgaacat gatacgtatc cctcttttat gtgcttcatc aatcaagttt
     2521 tttaaaagtt ttttatcgcc aaaagcggga tccacctcat aataatcaat cgtatcgtat
     2581 ttatgattgg atgtggcttt aaatatggga caaaaataga tgccattgat gccaaggtcc
     2641 gtcaagtaat ccaaatgatc catcacacct tgcaaatctc ccccgaaaaa gtcttctcgg
     2701 tctggatctt tacttcccca aggtaaagtg tgttcggggt catttgcttt gtccccgttt
     2761 gcaaatcttt cgggaaaaat ttgataccat actgtttctt ttacccattc tggaatagtg
     2821 aatcgatcga tttgatgaaa ataaggtatt cgaaaataaa aatttggttc agtaatcaca
     2881 ttttctcgat aaggaaaaat tccttgatca ccgtaaaaac agtccgtgtt atcttcccca
     2941 acaacatgga acgcatactg taagcgactt gtttcgctcg tcacttcaat ttcccaataa
     3001 tcatgaacat tggtacttag acattttttc attggtcgtt gtttttgata ccatttttca
     3061 gttgttatgg tatatggatc tccacatagc acatatactt ttttgatatc atttttccta
     3121 gtacgaagcc gaatacgaaa tcttgtattc gtatatagaa atgcatattc actttccggt
     3181 cgatgataaa ttgcagctgt atccattgat ttcctccttg tgttttaata tgacgtcatc
     3241 actataagtg atagagaagc aaaagacaac gctttcaaaa atgttatcgg taacagtttt
     3301 ttgataccga atttttattt tttaaacttg ccaaatagat agacttaaaa cttttaaaag
     3361 ttttagtcta cttcctgtac tatttagtgt cctgaattta tcttaagcga tcaatttctc
     3421 caattttcta aagtaaaagt tttttaacag tttttggcgt agaagtatat tctagaagaa
     3481 tgaaacataa taatttagac tagcctaatt tttttattaa ttaaagttaa cttaaggtga
     3541 aaagtaagtt ataataagat aagagtatta ttaatgaatt aaggaagtga ataaatgaaa
     3601 gaaacgagac aatttatatg gacatacatt aagattattt ttgccctctt catattagga
     3661 gtcgctatca atatgttttt agggcctcat catattgctg ctggaggtgt cagcggtcta
     3721 ggaatattac tggaagctgc tttaggcttt gaccgagcta tagttatttt agtgttgaat
     3781 atcgttatgt tggtactagc tcttctattt ttaggtaaaa aacccttttt taaagtactt
     3841 ttcggaagct tggtttttcc tttaatcatt gcaatagttc cagaaacaat gattacttca
     3901 gatcggttgt tgtctgtcat ttttggaagt gcgatttttg ctttaggagt tgcgatttta
     3961 tataaaaaca actcttctag cggcggtacg acgatccctc ccctcatttt taaaaaatat
     4021 ttccacttga atacttcgat tggcttattt tttacagacg cattcgttgt ttctcttaat
     4081 ctgtttattt ttggaataga agagtttctt tatgctattt tatctattgc aatcacttca
     4141 attgtcatga cttatatcga aacaggtatc aatcgaaaga aatctgttat ggtcatgagt
     4201 gaacattatt tggaagacat ccgccttcgc ttaagtgctg agattggacg tggccttacc
     4261 ctgctagagg caaaaggcgg gtataatcga aagtcaaaag aggttttatt gatcgttgtg
     4321 actgatcatg aattttcccg aatgaaacca ttgatagaag aaatcgatcc aagtgccttt
     4381 gtcattgtca gcagcgtagc agaagtaatg ggacgcggat ttacttatca tccaatcgaa
     4441 tgagttggta agtaaatccg ctattttttt gaatgcgttt tctttagctg gtataataaa
     4501 agaatctagt aactgttcga ctgaaaagga gaggagatct ttatgcataa aggaacggaa
     4561 atcgattttg tattaaatga tagtttgaaa gcactagaac tgtatcaaac aatctttgat
     4621 gaaatacaac tgattgaggc aacagattac cctagaggca ataatgaagt catttttacc
     4681 ttgtatggta cgagattcca tatgctggat gaaaacacgt ctcttggttt gactgctcct
     4741 actgctgaac atccaaatac gatctggttc aatatcatcg tctctgatat cgaggacaca
     4801 cataataaag cattacgaaa tggctgtgta gagattcaag aaatgacaga aatgatggac
     4861 tttggtgtga ctaactcaat gttcagagat ccttttggtt atttatggat gcttcatcag
     4921 gtccatcgtg aagtaatttt tgaagaaaga aaacaacttt ttgagaaata tatgtaatgt
     4981 ttatgatgag attatttttt gtctctgata ttttttgtat atgtttgcta ttcgagaaag
     5041 cgcgtctgtt tcatgtgctt tctcttattt atcttatgcc aatccatttc tttgctttcc
     5101 acaattatat tgtgtaaaat tcaattgtat aaaatataat taaaggtggt aattttatga
     5161 aaaaaatgta ttctacgaaa atgatcaaca caggcggacg ctctggagaa gtgcataatc
     5221 ccgatcgtac attcgaattg aatattgcag ctcctggtaa acgcgtcgaa aatgcaacca
     5281 accctgaaca attgtttgca gctggtttca gtgcatgttt taacagtgca ttagaattga
     5341 tcaaacagca aaaaaatatc tctggggctt ctactgtcag tgcacaagtt tccctttatt
     5401 cagaaagtga aacgagcttt gtcttaggtg tagagattga aggatctatc gaaggtcttt
     5461 ctctggaaga aacgcaagaa ttattagagg cagcgcataa agtgtgtccg tattcaaaag
     5521 ctacagctgg aaatatagaa gttactctga aagcagttag tgaatagact tttttgtgta
     5581 aatccgctat gatacactat agtaaaacag cggaggtgga aaaatggaag atctatattt
     5641 agttaatcaa gtatgttttc ctttatatgc cgcctctaaa gaaatcatta gacactacac
     5701 tcccctcctc aagccgctga atcttaccta tacccagtat cttgtgatgt tagttttatg
     5761 ggaaaagaaa aagacttcag tgaaagagct aggaaatgat ttgtgtctgg attctggtac
     5821 gctgactccc ttactaaaaa agttagcaga aaaaaattat attaatcgtc agcgtgaaac
     5881 gggtgatgaa agaatcgtaa atgttacgct gactgctcaa ggtgctgcgt tgcaaaaaca
     5941 agcagaaggt attccacaaa agatcaagtc ttatcttcca cttgaacagg aagaattgga
     6001 tacactgcaa catctgaccc gaaaaatgct agataatttt catcaagacc agaaaaaggg
     6061 ctgaaactgc tagatgaacg attttatgag gaaaaccaac tcataagata acgtcattta
     6121 gcggtttttc tttttgctct ttcttatttt catattccat catataatga ataacgtgtt
     6181 tattttttgt tatttggagg ttgtcgattt gaccgtttat cagcgttttt tggcgaatga
     6241 aaaaatacgc cgtctcactg ttttattatt tgtcgttttt gttcttttct tagttagaag
     6301 tatgattaca accattttgc tcacatttat ctttacttat ttgatgattc atcttgttca
     6361 aatcattcag cgatttgtcc gaatccctac aggtgtttta gctatcatga tttatacact
     6421 gatcgtttac cttatctatc tggcattcac aaagtatatc ccgatgctta ttcatcaaac
     6481 atttgacatg atccagtccg ttattaattt ttacgagcat cagccaaaag atgcagatcc
     6541 tgttttacaa tatatccata cttatattga gcgaaacgat ttttttgaac agcttcaaaa
     6601 tggcgcttcg attgcgcttg gctatttaca ggatatagga aaaatggcag tggcgtttgc
     6661 tatgtcattc atcttaagtt tcttttttat gattgaaaag aaaaaaacaa ttgtattctc
     6721 aagattgttt ttaaaaagtg aattttcttg gttctttcaa gatatttact attttgccga
     6781 taagtttgtc aatacatttg gtttggtatt agaagctcaa tttgttgtcg ctcttttaaa
     6841 tacgttgctc actacaatcg ccttggctgt atttggcttt catcagctgc tgagtttagc
     6901 gatcatgatt ttcattttaa gtctgatccc agtagcaggt gttatcattt cttgtattcc
     6961 tctatctttc atagcttatt cccaaggagg catccgagat gttgtttata tcctgattac
     7021 gattttgatt gtccatctaa ttgagtctta tgtgctgaat ccgaagttga tgtccagcaa
     7081 aacagaactg ccgatttttt atacatttgt ggtcttactt gttagcgaac ggttctttgg
     7141 cgtttggggc ttgattgtcg gcattccgat ctttaccttc tttttagatg tattgaaagt
     7201 gaaaaagatc ccgaaccatc ttccaaaaga aacagatatc ccttaaaata aatatgaaga
     7261 aagataaagt atgaacgacc ccaaatatca gatttcaatc tggtattttg gggtcatttt
     7321 ctggatattt ctttttattt gaaaaatgcg ttcacagaca ttattcaaat gttagagaga
     7381 tctgttttgt ttaaatcttt ttgcagaaag cattgttgct atacttaata gaatgattcc
     7441 gctccacagt ataactttgt tttgtgactc tccggatttt ggtagctgtt tatttttcgt
     7501 ttcaggacag caaaggttgt atccttgcta ctttttaagg tttcagctga ttgggcgcta
     7561 tcaaatattc gtgatttttt attcagctgc tcttcattta tttttagaat tgctagattt
     7621 gattttttac tctctttttt tccatcctct tgaattgttt ttttgtttat tttttctggt
     7681 attccttggt ctcttgcgtc cgtatctggt tctggagtca catctggttt ttcttctgga
     7741 tctacctctg gtttttctgg attttcagtt tcattatctg tgtctggatt tgtttccggt
     7801 actgtttggt ttccagaatc cgtatctggt tctggagtta catctggttt ttctccaggg
     7861 gttatttcag gttttgattt attgtctggc tctggttgag tttctgtatc gggttcttct
     7921 ccaggttcta tttccggttt ctgttctccg tctggatttt ctgtaggcgg tacttctggc
     7981 ttattttcat tttctggttt atctgttggt tcttcaacaa gatctcctcc tgagtcgatg
     8041 gctgaatctt gctcaattgt ctgccgctga ctatacggcg ttaaatgatg atcgttcggt
     8101 agtccatctg ataccttgac agtaaaaagc gctggtttta acaagtcctg atttaatgta
     8161 acggtgaagg taaatatcgc ttgcttgtgt tggatagtca aagtgttctc gtcatagcca
     8221 atcgacaaag tgggatcaac attctcaaat gtaacagctg attgtagtat aggtgctaag
     8281 tctcccgaat agtcaatttt tgctttgatg gtcgctgttt gtccttttct taattttgcg
     8341 actcctgaat tgaaggatga aaattcatcc tgaaaggtaa ttcgattgac gttggcccac
     8401 ttggtttctg tccatttggc tgtttctgtc tcctctgtgt ggactgtctg atttatagta
     8461 agcgataagc ttaaggctgc aaatgttgat attaagatgg ttgaatatct cataactctc
     8521 tcactccttg atttttttgt atgcaagaaa taagatagta gagattctac ctatatgttt
     8581 actgtttttt tgtctaaatt tatgaaaaaa acagtaatat tttcaagttt taacaattta
     8641 agtaaaaagg agcctctttc atgcaaactc aagaagcgat taaaacgttt atcttgaaga
     8701 aaaaaagcaa tacaaaatta gatatttttc ttttcctatc tgaacatcgt ttctttatta
     8761 ctacacaata tttagcagat catttccata tgtctgaatc aaatttttta ctatacatca
     8821 aagaattaga acaagacttt gagcgtctca atctaacaga actgcatatt gataagcaaa
     8881 aacctttttt aaagttgaat tttgaaggaa ttgatccggc ttactgctat tatcgtctat
     8941 ttggaagata ctgcaacgaa tcagtcagtt atcagatctt gacttctttg ttcagctgtc
     9001 agacaaattc gattatcagt ttcagtcagc aaacaaacta tagtgcctct tatttgtata
     9061 cgaaaatgaa aaagattaat gcatttttag catagtacgg tttgtctatc tccttttcta
     9121 ataatggcag aaagtctttt tctggaaaag aggtacaaat tcaatatgca gcattagata
     9181 tttattggaa catcttttca agtactgcta cagaatttta tgatgaagat ccgcaagtag
     9241 tggcttttat gatgaatact ttttttaaaa aagaagtact tgaccgacta aatagcggta
     9301 tgatagataa attatatttt ctattaaaaa tatgtaaaga gaattttcct gcaacttctg
     9361 tgaaagacgt acaaaaagaa ttcacagagt atgaatatat tgactttttt attgatctct
     9421 ctgtagatat tttgcgacct aatctgccaa tttgtcgcga acaacgcatc ttagtgaata
     9481 ttttagctcg actttctatc acgaaaatcg aatcggaaga aacaagcttg gagcaataca
     9541 aacttttaaa aaaagcaaac gttcctcatg ttctttattc aagagaaatg gtggagtccc
     9601 tttgtactgt atttgatttg tttatacctg aaaaagaaaa gattctttac tcattggcat
     9661 tcgcacgaaa taaactttat aatggatttc ttaacttcaa tcaaccaaat acgccccttc
     9721 ctactttcat gctttatcaa gaacatagcg tattgaaaga agtccaaacc gccattgaac
     9781 aattttatat ggatttcaga gaacaaaatc aacacttgtt accagttatt ttagaaaagg
     9841 aaaatgtgca atggatggtt gaagacctag tacatttgta tgatcgctac aaaaaacagc
     9901 cgcgaattgt gattggtgtg aactatacgc gtgattttta tatcagtaaa gatctgatcg
     9961 ttaagataga acaaattttt tcaaatgaat cgatcaaaat acaaaatgat tttatggaga
    10021 actgcaacat cgttatcagc gactgccctt tgaaacaatt gccttctcat atcaaaaaaa
    10081 tctatatttt aaaaggaatc atcacaccag aagactggaa aaaagtgatt atgaggatct
    10141 cagaatatat ctttgaatta aaagaagaag cactcatgga tcaatcgaaa aaagaaaatc
    10201 aagttacttc ctagaccaaa taagatacat aaatccgaat gcttattaac aacctccgga
    10261 tttatgtatc aagaatttga acatccttct tatttacata ataaaattac agtttttttc
    10321 actaattatc tttacttttg tttccttttt cgattgcttc ccataatcca tttagataaa
    10381 cagcacctaa tgctcgatca tataagccgt atcctggtct tcctgtctca ttccagatca
    10441 ttcttccatg atcaggacgg atgtatccgt taaatccgtt gtcatacatt gtttttagta
    10501 tgcggtacat gtctaatgaa ccgtattcgg atttatgtgg tgcctcatag aaatctcgat
    10561 tagctaaaaa tttaatattt cgaacatgtg caaatgggat tcgatctctt tggcaaaatt
    10621 ctgctaaaat cccatataca tcattttctg gatcttctgc aatactccct gtacaaagag
    10681 tgattccgtt ataagggctg tctactatgc gacacaacca atctaaatct tctcgattct
    10741 ttacgattcg agctaatcca aaaatcgagt atggcggatc atctggatgt acagccattt
    10801 tgacccctac ctcttcacat gttgggatga ttgattggag aaaataggca aaattttctc
    10861 gaagtttttc ttcgtctact gatgcatagg cttcaagcaa ggatttgata ggagctaagc
    10921 gctcaggttc ccatcccggc aatccaaatt cattgctgga atgttcgatg cgcgcgacga
    10981 tttctcttgg atcatctgga atatcatcag atataaaagc taacgtggat gagccgtctt
    11041 ctaagcggta gtcaaggtca gatttcaccc agtcaaatac aggcataaaa ttatagcaga
    11101 tgacttctat tccatattct gccaagtttc ggattgtctg cttatagttt tcgatatact
    11161 gctcacggga aggtaatcca attttaatgg catcatgcac attgacgctt tcaattactt
    11221 ttagtgttaa cccacgagac tcaatttctt cttttagttc tttgatcctc tccctaggcc
    11281 atacctctcc tactggtata tccatcaatg tgcctacaat ccctttgacc gcaggaatct
    11341 gtctgatttc atctaaggta atcttttctt cctgtgatcc gtaccatcta aaagtcattt
    11401 ccatgataaa tttcctccat gttcttgtaa gtaatcctgt aatgtttttc gtacggcatt
    11461 tggtcctgct accatcttga tgaacatttc ttctattttt ctgccaagct ctgcttggta
    11521 aagatctaca ccaaaaattt ctttatttga caaaatagga gccattttct catgaatatg
    11581 tgatgtatct tgcgtaccca gttgaatatc ggaaagctta tgctgaaggt ctgtcaatag
    11641 tgggtctgga ctcgggatga atggttttcc ttgatcatca atgccaataa ggtatcgaag
    11701 ccaagcagcg agagtcaatg gtatgaatac aagtgtctgc gggtctttaa cttctatttc
    11761 catatatttt ttaatcgtct caccataacg aatcgccacc ttttgagagg tatccgtggc
    11821 gattcgctga ggcatattag gaatatttgg attagaaaag cgcacagtaa ttacttcttc
    11881 cagaaagatc tttggatcaa tgatacctgg agactccaca actgggaggc cttcattgta
    11941 cccgatttca gaaactagca gcgataaatc tggatctttc atctcctcag ctatgctcct
    12001 ataccccagt aaacaaccca taatagctaa agacgtatgc aaaggattaa ggcaagtcgt
    12061 caccttcatc gtatctgctt tatctaccgt tgcacgatca gtcaagaata ccccagcttt
    12121 ttcgaatttc ggacgtccat tgggaaaatg atcttccatg attaaataat ggatgtcctc
    12181 tgtattgaca aatggagcaa tattatttcc ttttgcggtt tggaaaatcg acatatttga
    12241 aaagccctct tttgccaaca ttttgctaac tgacaaggaa ggattcgggg tgatacgatc
    12301 aatcatcgtc catggaaacg caacaatttc ttcattcgat aagtattgga taaatgtatt
    12361 ttgtacataa ccttcctttt gccattcttt tgcgatcgtt agcaaagaag tacgtaattg
    12421 actaccgttt tgtgaaaaat tatctgtaga gacaagtgca atcggccaag ctccagataa
    12481 aaaacgttta taaagtagca cagcaagaat actcattgta tgtgatggct tctttggacc
    12541 attttttata tcgactgcaa tcggtcctat atatttatta tttgtatctt tcaatcgata
    12601 acctttttca gtaatagcaa aagtaactaa ttgtaaacta ggattttcaa agtgtcgaat
    12661 catcttatca aagtgttcag aacaatctgg atgacaatac agactgtcag ctgtcgcagc
    12721 taatatacgt ttgacgaact ctccactgct tggcatgacc acttcaagaa tcaaatcatc
    12781 aaaatcttgg taagcccttt caattatttc ttcatcgaat gtttcacaaa caatgacacc
    12841 agtggacaat tcgcctagat ccgctaaacg ttgagcgatt tctgcatgaa atcctcgata
    12901 aagatttccg ccaccgaaat ggatccagac aggatttttt tgtccatttt ctcttaatga
    12961 tgcacggtca aaatgaggta tttctacttc tttttgagat aattcaggga taaagttcct
    13021 ccagttgttt aaatcaatca tttttcccct cctaaactaa catattagtt tttgtattca
    13081 agtgaatttt atgcaataaa aatcgctatg tcaaccaaaa ttttactatt tatacaaatt
    13141 tactagttaa tgtgacatac cagattgttt ttcagacctc ttctgttata ctacgttcat
    13201 agaaatgatt ttggaggaat aaagatgaaa agcagcttgc aatcacaagc ttatcaagcg
    13261 attcgtaaac aaattatcta tgctgactta gaacctggaa ggaaaatatc tgaaaaggca
    13321 ctggaggaac atcttgctat cggccggact cccattcgcg aagcattgat tcaactacgt
    13381 cagcaagaac tcgtgtatac gatacctcaa agtggtacgt atgtttccaa aattaatctt
    13441 gtttctgcag aaaatgctcg ctttgtccga gaacagttgg aagagcaaat catgattgaa
    13501 tgttgttcca aattggacac acaaacacga atagtgctag aaacgatttt agaagaacaa
    13561 gaaaaagcag tcaaaataaa tgacgaacgc gcttttttcc gtgcagataa tttatttcat
    13621 gaagcttgtt tcgaaattgc aggaagaaaa gaagtttgga actggttaga tgaccataat
    13681 acccatttag aacgtttccg ctggttacga gtgaccattc aggggcttcc atgggaaacg
    13741 atcatggaac aacattatga tttactcaag gctttagttg ataaaaaacc agaagaagct
    13801 cgatttcaaa cgggattgca cttacacatg atgctgaaag aacaggaaac tgttactcaa
    13861 cgttatcccg agtatttcca gcagtagcat tttcttgcga cctcttctat ttttataatt
    13921 aaccttcgtt tttgagtaat ctttattaaa taacaaaata tccattgact ttgcaactcc
    13981 aactaaatta caataattat aaataaataa ttattattgg aggttttact atgtcattga
    14041 ttgggaaaaa aatcgaagaa tttaatgcac atgcttatca tcaaggagaa tttttagaag
    14101 tcagtgaaaa agatcttatg gggaactgga gtattctttg cttctatcca gctgatttta
    14161 cttttgtttg tcctactgaa ttagaagact tacaagaaca atacagtaca ttgaaatctt
    14221 taggtgttga agtcttttct tgctctaccg atacccactt tactcacaaa gcatggcatg
    14281 atacatcaga tgctatcggt aaaatcgaat acgtgatgat cggtgatccg tctcatcaga
    14341 tttctcgtat ttttgatgtt ttggatgaag agcaaggatt agctcagcga ggaacattta
    14401 ttattgatcc agacggaatc gttcaagcta tggaaatcaa tgcagatgga atcggtcgtg
    14461 acgctagtgc actgattgat aagattcgcg ctgctcaata tgtacgtacc cacccaggtg
    14521 aagtttgtcc ggcaaaatgg aaagaaagtg gcgaaacatt gaaaccaagt tttgatcttg
    14581 ttggaaagat ttaggtggtg gatatgttag acaaagaaac taaacaaaat ctcgaacaat
    14641 atttagcact gattgaatct cctattgttt tttctgttag tttggataat agtgaaaata
    14701 gtcaaaaact agctgaattt acgaaggaaa tagcagaaat gtctcctaaa atctcttggg
    14761 aaaaaagaga ttcgatgcgc acacctagtt tttctatcaa tccagttggc aaagaaagtg
    14821 gaatcgtttt tgctggtatc cccctcggtc atgaattttc ctctttttta ctggctatgt
    14881 tacaaattag tggacgggca ccgaaaatca gtgaatcttt gagtcttaaa atcaaaaaaa
    14941 taacacaaac attgcatttt gacagttatg ttagcttgac ttgtcataat tgccccgacg
    15001 ttgtacaggc attgaatata ttagctgtat taaatccaaa tattactcat acgatgattg
    15061 aaggtgggat gttccaaaaa gaaatcgatg ataaaaaaat catggcagtg ccaactgtgt
    15121 ttttaaatgg agaagaattt agtagcggac gcatgacgat cgaacaaatt gttgaaaaaa
    15181 tcactggccc tttgattgaa gaagagttgt ttgaaaaaga accttatgat gtattagtga
    15241 ttggcggtgg accagcagct agtagtgcag ctatctatgc agcacgtaaa ggaatccgta
    15301 caggacttgt cgctgattct ttcggcggac aagtcgttga aacactaggg attgaaaata
    15361 tgattggtac ctcttacaca gaaggtccaa aattgatgca gcaagtagaa agtcatgtgc
    15421 gtagttaccc tatcgacatt atgatgaatc aacaggccgt ttccttaaat aaagagcaac
    15481 attttattaa tattggctta gctaacggta tatcacttaa agcaaaaacc gccatcatcg
    15541 cgacaggtgc gcactggcgt tctatcaatg taccaggcga aaaagagttt aaaaataaag
    15601 gaattgctta ttgcccacac tgtgacggcc ctttatttaa aggaaaagag attgctgtta
    15661 tcggtggtgg taattctggt gttgaagcag caatcgattt ggctgggtta gcaaaacatg
    15721 tatatgttct agaattctta ccagaattaa aagcagatca aatcttacag gataaactag
    15781 tctctcttgc gaatgtcact gttatcaaac atgcagcgac gaaagaaatc agcggtacga
    15841 atcaggtaga atctctctcc tatatcgatc gccgtacgat ggagatgcat acactagctg
    15901 tttcaggagt attcattcta gtcggcttac tccctaatac ggattggcta gatggaacga
    15961 tcgaaatgaa tccaagaaat gaaatagtga ccgagaaaaa tggcgcaacg aatatccccg
    16021 gcgttttcgc agctggtgat tgtacagata gtccatacaa acaaatcatt gtttcaatgg
    16081 gttcaggagc tactgcagct ttaggagcat tcgattatct gatgcgcact tgagctatga
    16141 agattgtaaa aagtcagaga gcggaaaaaa ggatggtgac aagaattttg tcacaatcct
    16201 ttttgttttt ttgaataatc gctttttctt ctctttttct tatatactat aagtagtaaa
    16261 taatttgaaa aaaagaaagg tgactgatta tggcgcaaaa tcgtattttt acgacaagtt
    16321 ttgcaagcgt ttatcctatg tatgtagcaa aagcggagag aaaagatcgt ataaaagagg
    16381 aagtagatga aatcatttgt tggctgacgg gttattccca aacagaacta gaatatcaac
    16441 tacaaaaaca agtgactttc gaacaatttt ttgcggaagc ccctgtcccc aatccttcac
    16501 gttccttgat tacaggtgtt gtttgtggtg tacgagtaga agacatcgag gataacttga
    16561 tgaaagaaat tcgttattta gataaaatga tcgatgagct agcaaaaggc aaaaaaatgg
    16621 aaaagatcct cagaagttga tttttccaga gatattcttc tccttcgctc attttgtaac
    16681 atttaatttg gtaaaatgac tagttcacgt taaaataagt caaaggaggt tttcttatat
    16741 gtttgagacg attaaacaaa atattcaaaa atacgcctta ttaagagctg ctgtttatat
    16801 tatttctggg attgcgattg tgctaaaccc ttctgctgtt tttcatttta tcggttatct
    16861 gatcaccgcc tatcttgttt tgcttgggtt gttgaatctt tttgaggctt accgttttaa
    16921 aaggaaaaca ggttcttgga gtatcggtct gttcagtggt ctttttttcc tgatcttagc
    16981 tctgatcgtc tatgcttttg cacctgcaat cgtttctatc ctgccgattc ttcttggatt
    17041 agctgttatc atcaacagct tgttccagtt gttcttcagc atgaatacaa aagctaaaag
    17101 ttggagtgtt tatagtagta ttctgttgtt gattggcgga ttcgtcttat tgttcaatcc
    17161 attcaaaagt ttgatgcttc tattccaaat attcggcttt attttgattt tcatgggcat
    17221 ccaggagatt atcaatttca tcagaataag aaaaatgact atacgttaat catttttagt
    17281 tattaaaata gaccgtataa aaaccaacaa tccaaaaaaa tcttttggat tgttggtttt
    17341 tttgtgagta tattttccta ttttttcaat aatgtatgtt atgctaagtt cgggctatat
    17401 tttatacaaa ggaatgatga gaatggaatt tattggtatt ttatgcctga tattgatttc
    17461 aacaacgatt ggctcacata tctcgcggag attaggtatc ccagcagtga ttggacaatt
    17521 acttgttggt gttttgctag gccaagctgg attgaattgg gtcaaacctg atattctagt
    17581 ccatgacttt tcggagattg gtgtgatctt attaatgttt ttagctggtc tggaaagtga
    17641 tttatctctt ttgaaaaaat atttccgacc tggtatgttc gttgctttgc ttgggatcat
    17701 cttcccggtt gtttttggct ggttgacagg caaagcattc caagtttcgg gaaatgaagc
    17761 gattttcttt gggattattc ttgcggcaac ttctgtcagt atttcagtag aagtattaaa
    17821 agaactaaac gtagtgaata caaaagaagg atcaacaatt ttgggtgctt ctgtggtaga
    17881 tgacatttta gtcgttttag ttctaagttt cagcctatct tttctaacgg gggaagcttc
    17941 tagcaatgct tctttaccgc ttgttttgat tgaacagcta atttattttg tttttatttt
    18001 cttattagtc aaatggattg cgcctttcct actttcattt gcagaaaaag tgtacgcaaa
    18061 ttcttctatt atcatcgtat cgctagttat ttgtttagga atgtcttacg tagcggatct
    18121 tgttgggctt agctctgtca ttggtgcttt ttttgctggg atagctgtca gtcagacaaa
    18181 ggttaaagaa gaagtatacc acaatgtaga ggctttagga tatgcagtat ttataccagt
    18241 attttttgtc agtgtaggat tagaagttga tttttctgac tttagtgaac aactactctt
    18301 tatttctata ttgacgcttg tagcgatttt gaccaaattg cttggaggtt attttggtgc
    18361 tcagattgcc ggtttttctc aacatagttc attgatggtc ggtgctggta tgatttcgcg
    18421 tggagaaatg gctttgatca ttttacaaat tggacagcaa agtcaattga tcgaaccaca
    18481 gtactattca cctttagtta tcgtgatttt attaagtaca cttatttctc cacttgttct
    18541 caaatatttt acaaaaaaag tttatgaagt gtgagtaaat caaaaagaag ttgtgaaaga
    18601 gacatcgtga aaaccgttta tttgaaaaaa ggactgtgac gataacgcca cagtcctttt
    18661 actgtactta aaaagcaatt ttttattgat aattttggtt gaggtattgc aatagttccg
    18721 atgctcgttt ggttgctgaa tcatcatctt ctttattttc caacatgctg accatcatat
    18781 aaccttggtt atcaagattg aaagcaaaca agaaactgtt ctcttgcccc tttacatcct
    18841 gtttttcttt gatttccgct gtaccagttt tcgctgccaa cggaatccct aaagcagaaa
    18901 gagaatgtgc tgtaccattt acatcttgca caacttctct cagatctggc acgatcgttt
    18961 gtactgctgt ttcgctgatg acattcttct tatcttttgt ctctttatct gcaatcaatt
    19021 taggatagac aagtgtgcca ttgttggtaa aaacagaata cattgctgct tgctggatag
    19081 gagtaattag aagttcgccc tgtccatatc cagtatcagc tagcaagata tctgagttaa
    19141 agctatcttc attagaaatt tgtgctggat tcatactaat tggcaaatca aggtcttcac
    19201 caaaaatgaa tttatctaag cctgtacgaa attttttctc acccattttc aacgtttctt
    19261 gtgccgcata tatattatcg gaatagatca aagcagtttt taagtctact tgtgatacat
    19321 cactactgac acgcgttgct tgataagatc cccaagaact gtctttttgc catttaagcc
    19381 cgttgatcgt caacacttca tttggatcga tagtgccgtt gtcgagaccg attgctgctg
    19441 taatcatttt aaacgtagat ccaggagcat aacctgtcgc aaatcggctg atgaatggat
    19501 gttcaggatt ttcttcataa gctttgtaat cttcttgtga gatcccgttt gtcattttgt
    19561 ttggatcata gcttggagag ctagcaagcg caagaagatc accggttttt ggcgttgtcg
    19621 caacagttga tccagctttt cctcctagac tgtcaaaagc tgttttttgt gccttcgcat
    19681 cgattgtcaa tttgatatct ttgccatttt gaacttcatg ttcgatcaga acttttttct
    19741 ctacaccgtc tgcatctgta atgcttaatt tcccacctgt tgtcccacga agatccttat
    19801 caaaagccat ctccaaacct gagcgaccga tttttccatt actgcttaat tctggattct
    19861 tatcaatatc ttctgctgtg atatctccca cgtaaccaat cagctgagca gctgcttcac
    19921 ccaaaggata atatctgccg tctacttctt gaatggtagc tccagctgga agttctggcg
    19981 ttgctccatc aatgattttc aatgggacaa agtaatcggg ttgtacccag ctttgtgaaa
    20041 tcgcctgatt gatagcatct tctgttaagt cgaaggagga agcaatcgct ttgatattgg
    20101 ctgttttttc gcctccatct ccaagtttac ttggaacgac tcctaattgt tttagtttgc
    20161 ctgttgttgc taatggttca ccatttcgat ctataatatt ccctcttgct gcttcttgtg
    20221 tggtcaggct tactttgtca tttccttcca tttctggaaa aaccaagttg ggttgccagt
    20281 tgatcgtggt ttgaccatca tttctgtcta atgttccttt ataagaaaga tctttcaatt
    20341 cacctaatga ggtattcatc tttgctttat atgaaaaact gtaagtagaa tcgtcttttt
    20401 tatctacttt tagattcgat atctgaagtc ctttgacatc agcagcaccg tatatattct
    20461 ggtatttatc taagatctct ttttcagata atgcactttt atttgccgcc ttttttgatg
    20521 tcatttctgc agctttgtta taatctccct tgttcaaagc ttggacaaat tgctcaactg
    20581 tcttttctcc agcttctact gcttgggttt cttgatagtg ctggtagtaa aaataaccgc
    20641 cacccgcagc tgctattaag atcactgcgc cggcaatata agcgcctgtt cgatttttgc
    20701 cgtgcttgtc acttcttttc attttttcct ccttctcttg cttgtcattc ctttatttca
    20761 ctatttatac ctgtttattc taacatatgt ctttgaggaa atccatacca caatccagaa
    20821 gcacactttc tggaaggttc gtttggatac taccaagtaa tttcccaacc gctttgggta
    20881 gcttgaatat tgaagttacg tctttcagct gctgagagat agctttgatc acttgctgct
    20941 gccttctgat cctcccgaag tctccttctt tgtcttcccg aaatcgagca tactggagta
    21001 aagtattacc atccatcact tgctctcctt tgtttatata tacgccatct aaatctagag
    21061 atttttctgc atcgatcttg actccaccag gaaacagttc attaacgcaa tcgataaaat
    21121 cttgaaatgt gatacttgca taatagggag cttcaaattt gaaattttcc tttaatgttt
    21181 gatttaataa atcaactccc ccataagagt aagctgcatt tatcttattc attccgtaac
    21241 ctggaatatc gacatatgaa tctctcatga tagagatcag ttttgcttgt tgtgttttct
    21301 ggttgtattg tgcaaccaga agtgaatccg agcgaccgtt ttcgtctttc gaacgagcat
    21361 ctgaaccaat caaagccaca tttagtgtgg tagggatact tttcggctct acctttttca
    21421 cagttgaact ctgttttgca gacgaaaatc catggataaa ctcaatcgaa aaatagccaa
    21481 ctactaatgt aagcagtaac aaaatagata atatgatttt ttgagatact ttcattgcga
    21541 attcctcttt ctaaaagaac ctctcgcttg aaaaataaaa gattgtactt tatgataatt
    21601 caaactgaga gtttctcagt ttctctttat tgtttttcag gtcgatagag cgccaactct
    21661 tcggcctgta tctttgaaga aatattcaac gtgattccga ttcctaaaga aaggatcaga
    21721 taacttgttc ctccgtagct aacaaatggc aatggcacac cagtcattgg catcagcccc
    21781 gcgatacttc ccacgttcat tatcgtctga acgaatagca aagttccgaa tcctaaaaga
    21841 aacaatccag cttgctgatt tttacagcga ctgcttaaac aaaagattct catgcataat
    21901 gagaacaata agaaaagcac acacaatgca ccgattagcc caagctcttc tgtaataatc
    21961 gaaaaaataa aatctgtttc tgtctctgga agataccctt tttttgtgat actatttcct
    22021 aatccccgcc caaatatgcc accattatat agtgcataaa acgaatgggt catttgatag
    22081 cccgcaccat gactatcgat aaaagaatct cttaaagtcg cgatcctttc ataagcatga
    22141 ttaaacatct gtggaagcca acctttattt cctaaatata ataccccgcc tgctgctcca
    22201 atcagcaatg cagaaaaagt aacgattaga tagatccctt ttttaaatgg aaccgccgct
    22261 gcccaaaata tgacccacgc aatcgaaagg atcatcaatg ctccagcaat ctttggctga
    22321 aataaaatca gaaaagttat acctactgta atcaggaatg gtttttttag atcttttggg
    22381 ctactatttc cgtcacgaaa aaaccagctt aaataaaaaa tcaaaaaaag atttgccagt
    22441 tcagaaggct ggaattgaat gccaaacaga gagatccaac gttgtgcgcc gttgacagtg
    22501 acaccgaata tccctattct tactaatact aaaaagaaaa tcgataaggc taaaccgtat
    22561 cctgctattt tagggtgaag taaatagtgt agtttgactg aacgagctaa gaagatcacg
    22621 ctccaactca aaaatatgaa aattagttga cgcaataata gactttttgt attttcatcg
    22681 gcttgcaata aacgataaga actggcactg tatacttcta aaagaccgat catggacaaa
    22741 gtcaaataag gacccaaaat ccaccaatcg atcttttttc accgcatctc ctcctcacac
    22801 agcaatccac ttgtcaggtg aggagcgagt ttgtctcatc aaataagtca gtcacaaaaa
    22861 tataaagaaa aggtcagaaa ccttttcgaa caagaattct gacctagcat catctcatcg
    22921 tccgagtttt agcactatac aacgtaaaga aaacattctt agctattgga aaaagcctta
    22981 atccaacagt ttctgtttta cccattggcg actttcgacg tttctgggca acagcctatg
    23041 tttgtatagg agcctcacct aacaaggtta ttactatatt ctatttacga gttcatgata
    23101 gacttttcct aatgattagg caatggaatt tgaaatgaaa tagtgaaatt taacaatctt
    23161 taatattttt tagaaaaaaa taacaaataa gttgaaagaa tcccgttgca aattctttca
    23221 gttgcaccag gattctttga taatttttta gttttatgtg tttttttata tgttttttca
    23281 cttttcggaa taaatattta tttgttaaag taattaaaca atccgctaat cgtttgatct
    23341 ggcatttcta tttccttacc atctaaagta acagtagtaa cgacaaaatg gtcttgcaat
    23401 ggcggaactt ctaagtactg cccttgcaga aaatcattca ctgtttcata ttcttttttc
    23461 atttcttttg aatctgtcga tggtttatag cttattttta acataactag tgctcctttt
    23521 tattcgggac gtgcaatcgt gaaaatttct cctattgctg cataatcatt tcctgccaaa
    23581 cggcttacag cattcaattt tcttggatcg atccttcctg tcttatcatc atagactgtt
    23641 tcatttaaat gatatttctg tacttctagc aaaaataaat cagctgttac tttattttta
    23701 ttccgtatct cgacatgttc atataaggat gtttcaaaac gaacttttgc ttctgtcaat
    23761 gctggtactg aaatgattac tgaatcagtt aaagtcaagt cagtcaggta cagttcgctt
    23821 tcctcattag gcagattggc tgctgtttta tttacttctt ctacgttgtc ctcatcaagg
    23881 atatggataa cagcttctct tgtctcaaga atattctttg ctgtgtcttt tactgcatct
    23941 tgttttctct ggatcgccaa ggataagatg ggtcgattcg aactgacgat attgaagtaa
    24001 ctgaagggtg cgatattcac tatatctttt gctgatttag tcgttactac tgctactggt
    24061 ctagggatga ctgaaccaat cagcaacttg taattttcac gttctgtcaa ttctgaagga
    24121 ctccgttcaa acatggtttc gccttctttc tataaaattc gttaaaaagc agatcttgaa
    24181 gacaaaatga aaagtaatgc ttttttcatc ttcttagaat ctgctttaaa ctatctatca
    24241 atttttcttt tttgtcaaga atctgtgccg tgcgtgtttt ttagttattt gctttacttg
    24301 cggcttcgac atatctttta gtgatcaatt gcggacgggt gataatagat ccaactacga
    24361 ctgaaaaagc acctaattca tatgctttct ctacttgttc aggagagtca gtatgtcctt
    24421 ccataattac tgggatatcg acttgttcta tgatttgatt caataaatca aaatcaggtg
    24481 tctgcgtctt tcgtgaatat tctgtatagc ctgctaaagt cgtagacaaa agatcaaaac
    24541 catcttcttg cgcttgaagc gcttcctcaa aagtcgaaat atctgccata gctaaccgac
    24601 cgtgttcgtg aatcatttgg acaagttcag cagttgtttt ttctgtcgga cgtttacgag
    24661 aagttgcatc cagtgcaatg atttctgctt gcgtctccaa aagttcttcc acttcttttt
    24721 ctgtcgcagt aataaacact tctgacccat cgtaatctct tttgataatc cctattaccg
    24781 gtaaatcaac gattcgcttg atttcattga tatcttctgt cgtatttgct cgaataccaa
    24841 ctgctccgcc ttcttttgca gccaaagcca ttctccccat aataaaagaa ctgtgtagcg
    24901 gctcgttttc caaagcttga caagaaacga cgactccgcc tttgatttgt tccagtgtat
    24961 ccacaatatc tcctccagta atgttatata aaaatacagc ttcatataaa aatgtaaccc
    25021 ttttctattc aggagacaat aatgagctat ttctttcagc agacctttct tactaaaaga
    25081 aaattacttc aaattcttcg tatacgacca gcttctcttc tgtaaattct atgttcaacg
    25141 cttctttata agcatgttta aaaaactcag catggacttt ccgccaataa gctaatgtcc
    25201 gatccccttc tccttctttc caagcatgct ctttcgtgac ttcactaaaa ggcaagatgg
    25261 tcacatttat atttttgatg atacaaactg gttcattttt tccattcagg accacgtcta
    25321 attgaccaac ttttggtaaa ggctcattct cttgtttata cagatcgtaa ccacttgatg
    25381 taccagtctt tatctttttt acaactagtt cgctcaactc gtctgccatt ttttctgtat
    25441 ccccaaatga aaagaaacct aatttttctg attgataact aggatatttt tcttggaact
    25501 ttttgacata ttcttctact tgctgataca taacatccac ccctttgctt tttataatga
    25561 aaaaaccatc cagatactag tataaacaat tatctggatg gtgagcataa tgaattattg
    25621 aatattcaag acacgcagac tatcttcaac gatttgtttt ggtgttaaat gataacgttc
    25681 ataaagctgc cctacaggaa cgctatccgt gaattctttc tctgcaccaa aatttaatac
    25741 gttcattgaa gaatcaccat aataacgact gatattttcg ccaaatcctc ctgacaaact
    25801 accatcttct aatgtgatga ctaattcgtg tgtttctttt aatttatcta atgtttctac
    25861 gtcattttct gtgatcgttc ctggattgat caacgttgct tcgattcctt tttttctaaa
    25921 agcttttact gtttcttttc ctaattcaag aaaaccgcct aaagctaaaa ttgctacttt
    25981 tcctccatta tttactgttt gataggctgg aatactataa tcatttgcga tagctgtacc
    26041 atgttctaca ccatgtgtag gaattcggat tgctacaggc tgcgctgttt gttcgaacgc
    26101 ccaatctagc atagagatca tatcctcttt tgttgctgga gcaagatatt tgatgttcgg
    26161 gatacttgat aagtaaggaa tgtcaaatgt tccttggtgt gttcggtcac tagctgagat
    26221 cgttccgcca ccgactaaaa taatcactgg attctcgttg atcgctaaat catgtgataa
    26281 ttgatcatat gcccgttgca agaaagtact tgattggaag acgactggac gtactccctg
    26341 agaagccaaa gcagaagcga aagtgataga gtgctgttca gcgatcccca cgtcaaaata
    26401 atgatctgga tgtttttctt ggaatgtttt cagtccaaag gcgcctggta tcgctgcatt
    26461 gactgcggca ataggagctg tacttgtttg cattttctta tccaaataat ccatgatgat
    26521 catattaaat gtttctccag aagttacttg ctttgcctcc ccggtggaca gatcaaatgg
    26581 tacatgccaa tgatatttca ttttattatc gattgccggc tgataaccgc gacctttttc
    26641 cgtatggacg tgaagtacaa tcggatgatc aatatctttt acttcttcaa ataaacggat
    26701 caccgtttcc agatcgtttc cattatccac gtaacgataa tcaaatccca ttgctttaaa
    26761 taggttattg ctgcttttac cgttggtttg acgaagctca gctaagtttt tatataaact
    26821 gccatgattc tcatcaatag acatctcatt atcgtttact aatacgatta gattggattg
    26881 taaaacacca ccattgttca atccttcaaa agctaagcca ccacttaggg agccgtcacc
    26941 gataaatgct accacatttc ctgattcttt cttcagatct ctcgctttag ctaaacctgt
    27001 tgctaagctg atagatgtag atgtgtgccc cactgtaaaa tagtcatgtt tactttcatg
    27061 ttggttggaa tatccgctca cttcacggta atgtcctttt tcaaaaccat tttttcgacc
    27121 agttaaaagc ttatgaccat aagactgatg ggaaacatcc caaacgattt tatcctttgg
    27181 tgaatcaaat acataatgaa acgcaatcgt taattctact acacctagat tcggaccaac
    27241 gtgcccacct acatcgctgt ccttttgcaa gattttttgg cgcatctctt ctgccaactg
    27301 tttcatttcc tcaacagata attttttgac atctgcgggg ctattgattg catccaatac
    27361 atgtaatact gtactcataa tacattctct cctccgtact atcttctttt aatgaaaata
    27421 gatttgttac actttatcta ttctactact tagagttgac tctaagtcaa tagcatttta
    27481 aaaaaatttc agagaaagct tgttatataa gtagatcttc gcacgaatca ggactcaaat
    27541 aaaaaccttc tacagacaat taaaaagctt tgtagaaggt ctcctaatta aggtctcatc
    27601 aagaaatatg tttttttaat aggtgaagtt cctgagcaat atgatacaaa tggatgtttg
    27661 caccttttaa tgagattgga tagatctttg tcttttcagt ttctaatcca ttttgatagc
    27721 tagcagcatc gcacaaaacc actctttttt tcgcacatag acattcatca ggcaattctt
    27781 ctaatgaacg aaataaaata ggatttattt cagcgatgcc ttcttccgca tacaaatgaa
    27841 attgggttcg ataaaaaaat tgtttgactg aactttctga aacaacaaaa atttctattt
    27901 cctgtctccc cgcttgttca ctgttgatca aagaaagact tttgacgaat tttcgaatga
    27961 aattttcatt ccatcttagt tggatttgat ttttcttttt ccactcttcc aatatttcta
    28021 caatttttcc gtacagaagt tgttcttttt ctgatagaag atagatcctt tccggtaaaa
    28081 atacttgtcc atctgcccac aacgtacgga caaattgtaa aaaggattgc ttgaaaataa
    28141 aattttctgc atcgtcgatt tcagcgatac taataatctg taaaatcaat tcattcagtg
    28201 ataggtcatt gagaacaaaa tttttataaa caacttcgaa atcttttctt aacagctcca
    28261 tgttctcatt ggtataattt ctactgttga acaaagaaaa aatataatag acatcttctt
    28321 cttgtaagtc tagaattcct ttttgctctt ccaatccttg acagactaat tgaaataacg
    28381 gcttcgtttc tgcgcttttc ttatcttctt ctttcagtcc aaggggaaat gcctttcttc
    28441 cgattgcgat ctctatttct cgtatgataa aggacttttc atcttccgaa tatcttcttt
    28501 taaaaaaatg agtctctaca taatcaatca actcgttaca agcttcttct acatacggat
    28561 ttttattttc atagccttcc caattgacat aacgtactaa agctagcaag atgttccgcg
    28621 agtcaaattc tgggataatg atttctttat ttttcaaata atcattttct ttaaaaaaat
    28681 ccaatacgat ttttttgatt gtatatactt tactcaaaga aataaattca agatcagcca
    28741 gttctgtact cgtgaatata ccattaaaat aataacttaa aaactttaaa aaataagatt
    28801 gaccgtacag aaactgtgtg agctcagaaa gagcaatacc atgtttgaat acgagtttat
    28861 acttatgctt ctctcttact tgttctttta tacaatattc tagacactcg gctagacttt
    28921 ctagatcgtg aaggatcgtt ggtgtagtca cccttagaga aatagctgtt tgttcgatgt
    28981 ctatttcttg gaattcaaat aattgttcac acagatacac ttttctaaat atatttcgct
    29041 cgatgtaatt ttccagcatt cctgatacac gcctccagtt tttcttatga ttttatttaa
    29101 tcatatctgt aaatcgtatt tttgtttcct ttttatttag aaaagccctt tcaaaaacca
    29161 ataaaaaaag aaactgggac aaaagtcaaa caagctcaca atttcagcct cattgtaggt
    29221 agctttgagc cgtttggact tttaccccag cctctttcaa gaatggttat tcaaagatgt
    29281 cagcgtctag ttctttgact acatctttca acaattggat accagctgcg ctgttaccaa
    29341 atggatctag tgccgggctg aagacaccta tgccgtaacg atttggcaca gctgccatca
    29401 acccgccgcc tacaccgctt tttgcaggta caccaacatg gacggaaaac tctcctgatt
    29461 catcatacaa accagcagtt gtcataattg atttgacgat tgtagcactt tcttcagtaa
    29521 tgatttgttt gccattccaa ggagcaattc ctttatttgc cagcacagca gctaattttg
    29581 ctatgcctgt agcggtgaca ttgagggagc attgtctgaa ataagcatcg agtatctccg
    29641 gtacgtctcc ttcgatcatt tgattacctt tcatatagta agcaagagag cgattgatat
    29701 cacctgttct tgattcagaa tgatagattt cttcattcaa tgtgatatta ggatcatcac
    29761 agatctcttt cataaatgac aagattcgct caaatttttc atctgcatct ttaccggcaa
    29821 tcaacgaggt tgttgcaatc gctcctgcat taacaaaagg attcattgga tgtttgcgat
    29881 gattgatttc catattcatg atagaattga aggcaaaacc ggttggttcc gtgttgattg
    29941 tttgaaagac tttttctatt ccgttgtctt tgattgctaa taacaatacg ggaacttttg
    30001 acatgctttc gatggcaaag cgcacatcgg cgtctcctcc ctcaatcagt tgttttgtat
    30061 ccaaatcata aatcgccata cctaattgtt tgggatccac ttcagctaat gctggaatgt
    30121 aatccgccac ttgtcctgtt tgataatagt ggaaattttt tccaatcaat tgttctaatt
    30181 cttttacttc catttgaata accagctttc attttttatt tttctgcatg ctggaattta
    30241 tgacggcatg cgtagatcgt aaatggaata actaagacga taagataaga aacaatcaga
    30301 atcgtttcat aaatcccatg ctgtccagct gcgatactag caggtggaac aaatgagata
    30361 caaaaagcaa aaagtgaagt caaaagacct aaacaagcaa cgattacttt tacaactttt
    30421 ccgcctggaa cctgataggc tctttcaaga ctgtcatctt taaaaaccag cttcaaatag
    30481 cccgcgaaaa acataaagta caacatcagg tagattacaa cagtcaatga catcgctgca
    30541 agaaatgaaa gattattccc cccgccgctt aatgtaaaga cggctgccca gattgttgca
    30601 acgatcccat ttgcgatcat caaatgagca ggaacaccgt gtgtgttttc ttttgcaaaa
    30661 tattcaggaa gtaatccttc ttctgctgct acgtgaagtg cttttgaagg agaggttacc
    30721 caagaagcaa tttctccgat gacacctaaa caaacaagaa tcgcaagaat tttcgcaatc
    30781 catgcaagat ttggatcaat gtgtcttaat aggaattcta acgattgaat cacccctgta
    30841 ttaagagaca aaccatgttg aggtactgta gtagcgacgg tcaatccgcc aaaagtatct
    30901 aaaatgattg ccagaataac caatacaaac attgctaatg gataatcctt tttagggttt
    30961 tccatttcat ttgcatgact ggcagatgtt tctacgccca tatatgctaa aataaaggaa
    31021 acaaaaacaa ccagcgtagg caatttcgaa aaatcaggaa tcaatgtttt catagacagt
    31081 atcgtttgta gtggagcgcc tgaagcgaca taatggatcc ctaagccaaa caagactaat
    31141 gctggcaaca agataccagc tacaaaaccg atccgagcaa tcaatgaagt gtatttggtt
    31201 ccttttaact gtgagagtaa aatagcccag aaaataatca ataggattgc caatttcaga
    31261 tatttattgt tttgtatagc accaataccc gttgcatagg ataatgcacc agttaagaaa
    31321 tacagcatgg tcaagtagcc aactgttatc tcaaaccatt ggaaaaagat tgcggcaaaa
    31381 ccgaatcgtt ttcccaatgt gcgactgacc caagtataga caccgccggt ttcccttagt
    31441 taaaaatatt actcttgttg attactcaac tcttccaata aatcggtaat atatctcaat
    31501 ttcctgtatt ctttcgttat cctcattcgt tgttgcttca tgtatgagga ttttttctat
    31561 catggcattt aataatggtg ctgtcagttc ctttggtacg gaatattcct tgattaactc
    31621 aatccacttt tcagcaccta tcatatcctg ttccatttta cttagttctt ctcttaggct
    31681 tgttatctgc tgttccagtt ctatctgttc tttttggtac ttgctggaca acatcacaaa
    31741 atttcgctct gttatcttct cacaggctct atcttcatac attttcgcaa ataaacggtc
    31801 aatctcattt tgtctgttct cggctttctt caatgtactt gcctttttct tcttttcccg
    31861 tattctctct gcattgccag ctttctgtat cttgttcaat accttttctt cgtcctgctg
    31921 tactgcctta gcccaatact gcaagcgttc caatacggct tgatacagca catcataacg
    31981 aatgtagtgc atagaacaat tacctttgcc aaactgcccg tagtaactgc aagcataata
    32041 actgtaaggc gttttatttg tcttattcgt tccaaatctc atagaccaac cacaatccgc
    32101 acacttgaca agccctgcaa aaatcggcgt tgccttttcc tttgtctgtc tgcgtcttga
    32161 ttttatctgc tcctgcacac gatagaacac ttccttgtca ataatcggct cgtgagtgtt
    32221 ttctactcga aaccattcac tttcgggctt acgcactttc tttttgctct tgaacgatac
    32281 cgtagactgc atattgtgaa cactgtttcc gatataaacc tcacttttca atatcgcctt
    32341 gacatgagca atcgtccact cataacgctt actttcgggt tttccctcaa agatatgtgc
    32401 aaaagtaccg tatcttgtaa aatttagcca tgacgctgtc ggaacttttt ctgctcttaa
    32461 ctgctttgtg atttttgcac ttccgtaacc ttgataggct agggaaaaga ttttttcaat
    32521 aatccatttt gtttcatcat caaccaacag ttttcctttg atgtcagggt gtttcttata
    32581 tcctaacgga gcataagcac cgtaatgagc cccctccgca aactttgtct taaatgctga
    32641 tttgacttta cggcttgtat ctcttgccac ccattcattg atgatgttct taaatggtgc
    32701 aatctcactt tcgccttttt cgctgtctac accgtcatca atcgctatgt agcggacatt
    32761 atgactaggg aaatacaatt ctgtatattg tcctgtcata atataatttc tgccaagacg
    32821 ggaaaggtct ttcgttacaa cacagttgat ttttcctgcc tctatatcct caatcattct
    32881 ttgaaaactc ggtctgtcaa aatttgttcc cgaccagccg tcatcaatat attcatcaat
    32941 gacattcaaa tgatgttctt ttgcatataa acgcaacata cttctctgtg tggtaatgct
    33001 ggaactttcg ccctgtaatt catcatctcg gcttaaccta agataaagtg cagtattgta
    33061 aatctgttgt ttcattgtca gttatcctcc tttataacta acccgtgttt acaatacctg
    33121 cttgcaagta aagtataaca cgggtacttt ttgtcattca atctatttct tacaactgca
    33181 ccgattttat gcgattgtct gctttgcttt ttccagcatg acatcagtta gaagttcttc
    33241 cattgttttg cccttttcgg aaaaatgctc ttttactaca atctttgtct ttcctctgtt
    33301 gccaatgcca cacttgccat ttttcttttg aattgttttt acagcattat caataacaca
    33361 tacccccttt ctgtaaaatc tttctaagca attcaacggc ttttgtcata gcccacagga
    33421 gttccacctc tgcatagttc ttatgtagcc gtacccattg cgtgcgacgc tcttaatgct
    33481 caagctgtgg ctgtacggga gtatcattat ctgacagtac aggtcatggc gataaaagag
    33541 gacaaatctt ttacaagaac acaaataggt tttcgctcgc tcttgcaggg gaaaggtcgt
    33601 ggcgtatttg tttcaacggc tagctgtctg tcaaacgtat tgaatagctt tattcagttg
    33661 tcaaagaacg attgaaagaa aaaaatcgtc tttcctatat atcgcgttgg aaaagaggag
    33721 aaacgtaacc aaaatccaaa actttttcca ttattagtac aaatggaacg gttcattttg
    33781 gcaatcaacg gttgattttc tcctttttca ctactatctg tacagcaaac gtccatttgc
    33841 taagtttaaa tggaaaaatt ttaacttctt ttcatgcacc atatagggat agaaaatgtc
    33901 attttgctaa gttgatgatg aaaaaagaat attttccttt tcacacccta actacccaaa
    33961 ccataccgtt actgccaaca atagaatgaa atattttctt tgcaccatat agggaacgga
    34021 aaccttaaat tgttaagttg agaacaaagt attttcatct tttcacatca acactcaact
    34081 gctaatgcct gtttgaatac aaaatgatga tgtttttcct cttttcacag aagactgtcc
    34141 actaatcacg aatttccgtc attttttcaa aactattttc ttctttcact tcatataggg
    34201 acagcaagcc ccgatttaat gacctatttt caaaaaaagt ttagatttcc ttttctcgca
    34261 ccatatctgt acgcaagtag ccattttgtt gcagatttaa taaaaaattt atttttcttc
    34321 tttcacttca catagggaat gaaaacagct ctttgctgac taaatctgaa atttttcaat
    34381 tacattaaaa aataccgtca ttctcttgtg gaacagcggt atctatacgt tcttctatgg
    34441 ttgatttctc taattgtaat aaatgtttat gcttgtcttt tagttctgcc tgctcaatca
    34501 tatctttcag tatcgttgta cgattttctc tgtctaatgc ctgtaccatt tttatggttg
    34561 gtgcgacttg tctttgtagc caatgcaacg ctttttgtaa agtgtaaggc tctggctttg
    34621 tggttaagcg tatcggctct ctgttttccc ctacaaacca tgcccaatca tcatttgtta
    34681 tccattgact ttttggcttg tcgtcctctc tgtcaacaaa gcggacataa tgattgatga
    34741 tagaaaaagc ggtgcgttca gcgtcccgat aggtcagtaa atctacaacc gcataatagg
    34801 ctcgttcgtt cttcatgcgt atttcaaaac ggttcttaat ctccgtatct tcaatttctg
    34861 tgccattctt gacatactgc tcataatttt tctgataagc acacatatat aattcgctac
    34921 ttgttgaacc gagatataag gtttctcctg tattctttgg taaatcgcta ccgcattttt
    34981 ctgtaccgct gtaatctttc tgcatacgga agtaggacat acattcgcca gccttgtatt
    35041 tttcctttaa ctttggaata tccaatattc ctgctttatc attgatagcc aaatcaagcc
    35101 gtttcatcac accaccagcc gtcatacaat ccagcatgaa gtcataccat gagcgttcct
    35161 gtgccagcag ataacattcc atttgccgac agcctttgcc tttcagttcc aataaaacac
    35221 ctaaatgctc ctgcatggaa cacatgatat tgatgtcgcc aagtacatat ttgctttcat
    35281 atccgtattt tccataatct tcataaagca tgtaattaga tttcagttgt aatacatcac
    35341 ggataatcgc caatgcgtcc gtagtaggaa agcggacacg aaagtaatca atcaataaga
    35401 atagtggttc ttgcggattg aaacgctcaa tctgtttttc tatgatttct cttaattcgt
    35461 cattcaatgg ctgttttcct ttttcaatgc ggttgtaata ttcacggctg ataccacagg
    35521 caacagcaag ccttgtttgt gttactccgt attcctcacg cttttgtctt agttcttcaa
    35581 taaagttttt atcattcatt cttcaattcc tccaatcaaa aaaggcaact accataattg
    35641 ataattgcct gtcattaaaa atctgtatag aaaaagcagt caatcctaag actaactgct
    35701 ttgtgtgtat ggatataaaa ttgcttctaa tcttgaatag gtatccaaat ttcaataact
    35761 gaattatcac tattccaatg aaaacgataa tcgtattttt caaagtgtag gataatatct
    35821 tttataggaa tatacgatgt actaggaata atttcttcat aaatcttgcc ataagtttca
    35881 tatattttat ccatagcacc aatatgctcc acaaccaaat atttataaga cggtatttct
    35941 ttatacagaa agccctctgg ggtaatggtt ctttggggaa tagaacagaa ataataaagt
    36001 tttccatttc ttctttccat aaaagcatat tttacccaat ttcctgattg tgaaagatac
    36061 gcttttttca aactactgtt aaactttctc caaaactgtg tactaatctg aatattcttt
    36121 ttttgataat tagtcagttc tacttcctgc ccaataactg caaatgcgtt taattccttt
    36181 atagaaaaat ttatcatttt accttgtgag cagtgataac ggtataactg tacgcattta
    36241 ccgttataat acaattatca atcgttatat accagttttt tccttttctt gtgatttccg
    36301 cattagaaag gctaattttt tctttgcacc attcaattac attttctaca ttcaaagata
    36361 agttcttttt aattctaata acgccaagtt cagttgtgtg aagtcttcct aagttttcca
    36421 gtaattcatt ttccatattt tgatacctca tttttcagca aatttatttg tatgttttat
    36481 accccaatta taacattctc atatcagcac tacaataaaa ataattaagc accaataatc
    36541 ttattgaaca tctccaaccg taaatctttc acaccatcag tgataaacac tgagctgaca
    36601 gcaattacga caactaccat aattgcctgc acttaaattt ctgcaaaaga aaacgacaat
    36661 caatttctta ttttttgaaa tcaactgtct ttctcatatt tactattcaa ttttcatagt
    36721 gatataggta caatttatat cactactgta aaaatggggt tttgccttat aaatacagcg
    36781 ttttccgctt gttagtgtat agtgtttctt gttttttgtg ccccccttgt tagataacgg
    36841 gggctttgaa cggctcgcaa gctcgccgaa ccgccgaagc gaaccgcccc cttgcaagca
    36901 tggcggaaaa atcttaagga ttttcccgcc aacgtggtcg gatcgctccg tcggtttaac
    36961 agcttttctg tttctctcta gttatctacg catataaatc aaatcggtta ttccgttata
    37021 agtctgtgtt ttacaaagcc ttaactttat ttccctgtct atgttgccca aaagacgaac
    37081 cccatttcct aacagagtag gaataacaga aatgtaatat ttatcaatca tatttttgct
    37141 taccaactgc tgaacaagat ttgctccgcc acaaatccaa atatcctttc ctgtttcttg
    37201 ttttagccgt tccaataata aaacaggatt ttcacttgta aaatgaattt gttgggaaga
    37261 attgcactct ttatgtgtta atacataagt tgtaaattta ttatataccc attcttgcgg
    37321 agaaagttca gtaacaacct gatgagaagt attccacccc attaagacag tatctatatc
    37381 tttggtaaat tctgtataag tgtcgatgtt ttcattgtca tttccatgac catttagcca
    37441 agctactcca ccattaccgt ccgcaatata tccgtcaagg ctcatggcaa taaataaaac
    37501 tacttttctc attttttctc ttttataaat acaaacagga atttatttct cttttttact
    37561 cataagggaa caactgattg ctacaaataa acccattaaa atccatggaa atgctgctct
    37621 tataaaatca ctaaccatac tttattcctc cttaaattcc aatttcctta gttctacaaa
    37681 ctgaaatttt tgcctatgaa tgtatcttgt tctttatacg caaacaggct tctgtgtgca
    37741 taatccaatg tcttgaaaac ggcatttgaa ttagtccaca aatatcttta ttacaccaat
    37801 aatcaatcag ccaaattgct ttttcattgt cgtttactac attcaacgat tctaagtatc
    37861 cttttctttc tttcggtatt tttcttttca attcatcata agataaccgt tcaagcattt
    37921 tctcagtgct ttcccatact tcgaaaatat ataaatataa ttcttccaga ttaagctgtt
    37981 ttgaaaagtc tgcaatctgc tgtttcatga gttcatttcc tgttgtaatg ataggtgaat
    38041 tgatacgctc ttgataattg cctgcaaaaa atacttgttc atcttcattt atcactgtat
    38101 gcacaactat atcttcaatg cggaaaatat gccaaataga ataagcaatc gtcttactat
    38161 gataaccatc agcgtttatg aaggggattg agttaaaatc ttctctgcat aattcttctt
    38221 tgaaagatac taaggtttgt attaactgac ttcgtaaagt aagtaaagta tcaatacccc
    38281 tcttataagt atctttcttt tttatttgtg cctgcattgt tttattaagt tcagaccatt
    38341 ccttattcat attcaatcct ctctcaaatt ctgattttat cgccccatac aaactggaat
    38401 ttgtcttaca acaatttata tatgcataaa aagcaatata tttatgaaaa caccctaaat
    38461 ccaaaattta ctcaattcat tttttcctta cataaaatgt tctcgtatat ttcacttcct
    38521 caccaagtgt ttcccctatc aaaacttcaa aatcattgat atcaaattct ggaaagaatg
    38581 tatctccatc ttcaatattt aaatctactt ctgtgatata cattttatct actatttgca
    38641 aagcttcctt aaatagtcca tatccaccag atatgtatac atctcgtcct ttagccaata
    38701 ataatgcatc ttctaatgat ttaactgaaa ctaaattatc tccttgatac tctgttgtgg
    38761 tggaaacaac aatattcatt ctattaggca acggatgacc gatttcttca taagactttc
    38821 gccccataat aaccacatta cccgttgtta actctctaaa ttgcttttgt tctcccttta
    38881 ttttccatgg tatattacca ttcttgccta taacattatt ctttgacctc gcaacaatca
    38941 aacctatcat ctatttcatc ctccataata tgatgtcgta cctgtgattc catcaagtgc
    39001 accacatctt aacaaactca aaattatctc gaactaacca gctcgacaaa ttcctttttt
    39061 gtcttcatct gcattatatc atattgttat aagcattgcc atttcttttc tgcttttgaa
    39121 aagttactta tcagcctatg ttttgtaaag ggtgatattc agcatttctc acgcaacaag
    39181 cccttgacaa accatagact aataagtttt aaggtaatca agcagaaatg aaatagtctg
    39241 ctgtttcacg gcaacaaaaa agagatacca acacacttat gtagtatctc ttagtctagt
    39301 agcaatattc ttttgtttgc aagcaggtaa acatgggctg tttcttaata tctttttgtt
    39361 tgggaaacac ctttttccca tcctttcacc gttgccatct ctgctgcgca caatgccaca
    39421 gggataaacc atagcaaacc gcctaataac aagaaaaata ctaagctgaa gcctgaggtc
    39481 gcgaatgtgg gatattcata taatgaaacg accattgaga tggtcatagc caaaaagcca
    39541 aagaacgtta atttttttgc aggaattttc gttttgcttt gttgcatgaa tcttcctctt
    39601 ttctatttga atttgtttca attgagtttg ttgccaaaga agaaaaagtc caatccttct
    39661 tcttgttctt cttttgtagt agtgatcgtt gtaaagtgca tcgccgattt taaaatcact
    39721 gttgtcagca cataggcata cacggcagta atgatgacac caatcacttg aatccctaag
    39781 aagtaccagc tgcttggatt cgttagtaaa tggctgttag atgcaaagat ccctatcaga
    39841 atcgtacctg tgaatccgcc catgccatga acaccccaca catcaagtgc atcatcccat
    39901 tgtttctttt tacgaaaatc aacagcagca tgacagacga tacccgcaat gatcccaatc
    39961 agcatggcac tttttgcttc tacataaccg gcacaaggcg taatggctgc caatccagca
    40021 acggatcctg ttagtacgtc gacaaaatca aagccatttc cttttacttt tgcaatgatc
    40081 agccaagtaa tcatcgcaaa tgcaagagcg atgaatgttg aaccaaatgc attgactgct
    40141 tgttcatctg ctcgaagtgc accaccggaa ttaaaaccga accagccaaa ccaaagcagt
    40201 cctgtaccga tagcagctgc cataagactg ctatgctgac ttctttctcc taaaggaatc
    40261 tttctttgac caagtgtgag gatacatgct aaagagccga atccagctgt cgtgtggatg
    40321 actgctccac cagcgaaatc tctaaatccc atctgatcca aaaatccgcc accccatatc
    40381 cagtggcaaa cagggaaata aatcagcaga ttccaaaaaa taacaagtat aatatagcct
    40441 tttaaattca atctccctgc aaaagctcct gtcatcaaag gaacggtaat cacgataaac
    40501 atcagttggt aaagaaagaa cattaaaaat ggaatcgttg caccatgaaa catgttgggg
    40561 aagcttgtaa catgtctcat caaaaagaaa tctgccgggt ttccaataac accgccgata
    40621 tcccgtccaa aggccaatcc gaatccacca aatacccaca taatcgttgt tatcccaacg
    40681 gagagaaaag attgagacat gatcgttagt atattattct tccgtgctaa tccgccgtaa
    40741 aaaaaagcta gaccaggagt catcaggcaa accattgctg tacataaaat catgaatgct
    40801 gtatctcctg tattgatagg taatgtattc atttttttcg cctcctttct acgattacga
    40861 gtataaaaga aggtgtagtt gtttttttct tctgtttttt tgaattaata cttgcattta
    40921 taaaagacag acaattaata aaagcttgat gtgttgtgct ctttttcgtt tttcacacaa
    40981 ataaagacaa aaaataaacg gtcttctttt tatagaaaac cgtttatttt cgtctttttt
    41041 tatttttaaa gatatttttt cataaggaat aaagaatact tcatataaaa tatataaaaa
    41101 agaaccgcag cgagtgtcgc tacggttctc aa
//
LOCUS       DACBZK010000017        38600 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.017, whole genome shotgun sequence.
ACCESSION   DACBZK010000017 DACBZK010000000
VERSION     DACBZK010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.017"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(99..1229)
                     /locus_tag="IVD66_000977"
     CDS             complement(99..1229)
                     /locus_tag="IVD66_000977"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HAP6145217.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     gene            complement(1878..3080)
                     /locus_tag="IVD66_000978"
     CDS             complement(1878..3080)
                     /locus_tag="IVD66_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6145218.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="IVD66_000979"
     CDS             complement(3140..3343)
                     /locus_tag="IVD66_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP6145219.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEQLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="IVD66_000980"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="IVD66_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            4880..5692
                     /locus_tag="IVD66_000981"
     CDS             4880..5692
                     /locus_tag="IVD66_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6145220.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6716..6868)
                     /locus_tag="IVD66_000982"
     CDS             complement(6716..6868)
                     /locus_tag="IVD66_000982"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145221.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="IVD66_000983"
     CDS             complement(7059..7937)
                     /locus_tag="IVD66_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP6145222.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="IVD66_000984"
     CDS             complement(7976..9094)
                     /locus_tag="IVD66_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAP6145223.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="IVD66_000985"
     CDS             complement(9091..11190)
                     /locus_tag="IVD66_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HAP6145224.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="IVD66_000986"
     CDS             complement(11241..12062)
                     /locus_tag="IVD66_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP6145225.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="IVD66_000987"
     CDS             complement(12059..12868)
                     /locus_tag="IVD66_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6145226.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="IVD66_000988"
     CDS             complement(12889..13383)
                     /locus_tag="IVD66_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6145227.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13883)
                     /locus_tag="IVD66_000989"
     CDS             complement(13395..13883)
                     /locus_tag="IVD66_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP6145228.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13960..16656)
                     /locus_tag="IVD66_000990"
     CDS             complement(13960..16656)
                     /locus_tag="IVD66_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6145229.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="IVD66_000991"
     CDS             complement(17084..18157)
                     /locus_tag="IVD66_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6145230.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="IVD66_000992"
     CDS             complement(18154..18981)
                     /locus_tag="IVD66_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6145231.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="IVD66_000993"
     CDS             complement(18982..19788)
                     /locus_tag="IVD66_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6145232.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="IVD66_000994"
     CDS             complement(19800..20885)
                     /locus_tag="IVD66_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6145233.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="IVD66_000995"
     CDS             complement(20902..21444)
                     /locus_tag="IVD66_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6145234.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="IVD66_000996"
     CDS             21702..22691
                     /locus_tag="IVD66_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAP6145235.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="IVD66_000997"
     CDS             22688..23425
                     /locus_tag="IVD66_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HAP6145236.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="IVD66_000998"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="IVD66_000998"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HAP6145237.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="IVD66_000999"
     CDS             23989..24621
                     /locus_tag="IVD66_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP6145238.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="IVD66_001000"
     CDS             24706..25353
                     /locus_tag="IVD66_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP6145239.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="IVD66_001001"
                     /pseudo
     CDS             25358..26341
                     /locus_tag="IVD66_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
     gene            complement(26744..28258)
                     /locus_tag="IVD66_001002"
     CDS             complement(26744..28258)
                     /locus_tag="IVD66_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HAP6145240.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28396..29202
                     /locus_tag="IVD66_001003"
     CDS             28396..29202
                     /locus_tag="IVD66_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145241.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29377..29946)
                     /locus_tag="IVD66_001004"
     CDS             complement(29377..29946)
                     /locus_tag="IVD66_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6145242.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30029..32089)
                     /locus_tag="IVD66_001005"
     CDS             complement(30029..32089)
                     /locus_tag="IVD66_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145243.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32366..33844)
                     /locus_tag="IVD66_001006"
     CDS             complement(32366..33844)
                     /locus_tag="IVD66_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP6145244.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(34142..35077)
                     /gene="murB"
                     /locus_tag="IVD66_001007"
     CDS             complement(34142..35077)
                     /gene="murB"
                     /locus_tag="IVD66_001007"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HAP6145245.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(35150..36070)
                     /locus_tag="IVD66_001008"
     CDS             complement(35150..36070)
                     /locus_tag="IVD66_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP6145246.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            36183..36935
                     /gene="xth"
                     /locus_tag="IVD66_001009"
     CDS             36183..36935
                     /gene="xth"
                     /locus_tag="IVD66_001009"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HAP6145247.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            37799..38332
                     /locus_tag="IVD66_001010"
     CDS             37799..38332
                     /locus_tag="IVD66_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HAP6145248.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT        11576 a         7961 c         6542 g        12521 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagctgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatataa gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gtcaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttgccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactag cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatcaaaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    26401 aaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggaattt
    26461 cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg
    26521 tcccacgctc tttttccgaa taaacggtgt tcaaaagctt gcatctgcgg taataagtcc
    26581 aaccaagtta aaaacataag aagctgtttt tacttggctg ttcttattac ttgatgcagg
    26641 gcagcttttt cacaacctct tcactaaaca gtgttcaatc agctgaccct cggtattagc
    26701 tcaaaacgct gatttcacaa cctcttttta tttacgttct atttcattca ttttccgaag
    26761 caaatcgagc tgcttgtatg cccgcttgtc gcccaaaaat aatgatctcc gcaactgaat
    26821 ttccaccgat ccggttgttt ccatgtaagc cacctgtgac ttcaccagca gcatataacc
    26881 ccctaattgg ctggttttct ttatctaata cttcagtgtt cgtattgatt ttcacaccgc
    26941 ccatcgtgta atggattcct ggtgcgattt tgatcgcata ataattcgga gacgataagt
    27001 catgttccat ggctgtggca cggttgaatt gagcatcttt tttctccgca acatccgtat
    27061 tccatccatc aactgttttt gctagtgttt cttttggtaa atcgattttt tctgctaatt
    27121 cttccattgt ctttccagtt gtgacatatc ctttttggtc ataaaattca atagctgtgg
    27181 cacgatcacg cacgccttgg tcaaaaatca aataagctga tttttcaggc aatgctgtaa
    27241 ttgctgcaga tactttatcc cttgtatcca tttcattgac aaatcttttc ccctcttgat
    27301 cgaccaagat tgctccttct ccgcgaacaa cctcaccaat caagaccccc tcatcctgct
    27361 gcacagttgg atgaatttgt attttatcca tatcaacggt ttgtccacct aatttttcaa
    27421 tcatggtgat accatctcca gttgatcctt cttgatttgt cgtaatataa tcagctaaat
    27481 cgggacgata tttttcaata aattctttgc tggcaccaaa accgcctgtg gtaactacga
    27541 ttgcttttcc ggtgacctct tttggttctt ctccttgaac atgtacagtc acttcattga
    27601 ccgtttcccc atttttctta atgtctgtca catctgcgtt gacaaaaata gggatttccc
    27661 gctcatggac gttattcaat aacccctcca ctaagtatcc accaatagcc gagccatcag
    27721 acggacgatg tgtcctcttt tcactcatcc ctccagtgat cgttaagttg tccagtttga
    27781 taccgttttg atctagccaa tcgaccgcat cagcagagtg atcgacaaag tatcgaagca
    27841 tttctttatc attcgttcct ccaccacctt ttagcgtttc ttcatagaag gcatcattcg
    27901 agtctttgat tccttcttct ttttgaaatt ttgtttctga agcattcata ccgcttgatg
    27961 atttagatgt gtttcctccg gcaacaggca tcttttccaa aattactgga ttcaacccag
    28021 catcttttgc ttcgatagct gctgccatcc ctgcaccacc agctccaata atcacgacat
    28081 cataagattc tttcatttct tttggatctg tatatacttg ttcagaagcg cctgatgata
    28141 cttcggcaga ttccttcgta ctagaacttg tctgcgctgt atttttctga tctgcgccgc
    28201 atgcgctcat agcaagaagt gcaacggctg ttaataaacc agcaactaat tttttcattt
    28261 gtatccccct tttctcctta tactatatta agtgattttt ttcacaatat caactctgtt
    28321 tttctttaag tcatatagct ttggtaaaca cacgcttctt agtataatta aggatataca
    28381 tgaaggagtt attttatgaa tcatttgaaa acctttttta cgaacagtac aaaaactgca
    28441 ggtagaatca caaacggaat ctatatttta ttacgtatca tcgtcgttat tatgctagtg
    28501 gatcaggtct ggaaccaaca ctggggaaat acaatgcttt tattactgac attaatttta
    28561 tttgaaatcc cttattttct ggaaaagata ttaaagatac agattccaaa tatgctagaa
    28621 atcattttgt tatcttttat ttttagttca acagttttag gagagttaag tgatttttat
    28681 ggctattttt caatgtggga tacttttcta catgcattca gcggattttt agctgggggt
    28741 gtcggctttt cccttgttta tttgctcaat aaaaatacaa aaaccatgaa cttgactcct
    28801 ttattactag cagttgtttc cttctgtttt tcgatgacag ttggtgttat gtgggagttt
    28861 gtggaatttt cagcagataa attactgcaa ttcgatatgc aaaaagatac gatcatccag
    28921 caaatcaata gtgtggagtt aagtaaagac ggaaacactg tctatcatgt tccagatatc
    28981 actcggacaa tcattgaaag tcaaaatgca gatggtaaaa cagataaaac aatcatccaa
    29041 aatggttact tagacgtggg aatcatggat actatgaagg atttatttgt taattttatt
    29101 ggagcagttg ttttcagtgt atttggttac ctctatagtc gaaacgatta ccaaaaattt
    29161 acgttcatca agaattttat tcctaaaaaa atcaaacgat aaaacatgct aaaaaacaag
    29221 agaaggggca gtgacaatac ttttgtcact gccccttctt ttttgaatgt atggcatgcc
    29281 attagttatc cgatagtatt aactcaaaaa agtaagatat gaggaatgac tatttcgttt
    29341 tttatcccaa tactgaggac ttatttcacc atttcgttat ttatctaatt tacttaaaac
    29401 ctgcataact ttttcataat ctggattagg tgtgccgtct agattttcag caataaaagt
    29461 aaaacccatt tttttataaa gagcaatcgc ctgatggctc catgtctgtg tgtgaagata
    29521 gattggtccg tccgtatgga gggtaggaaa ttcttgcaag actctggcag tcaatgcttt
    29581 tgcgagccct tttccttggt aatctggttt cactgctaac caatgaaaaa ccggatacac
    29641 ttgctctctt gatttttttc gccaagcggt acaggttgct actttttctc ctttttttgt
    29701 ctctacaaaa aacatccttc tttcaagttc ttcaggataa ggagcaaagt tttgttgaaa
    29761 atactcaagt gcttcatctg tcgtttgaaa ttccccaacg gaagtctcaa tctccgccca
    29821 agcagattca tcttcttttt gataaaatcg aaattcaaaa ccttccgcta aaggcgtgat
    29881 tggaacattt tgttgaagtg gtcttgtcat ccagatttct gcgtaaggta acgttttatc
    29941 taacattttt ctatccctcc tcgtctccat tatgccaaat aacatatgac tcagctactt
    30001 atttgactat aacagataga gatataaatc agaaccagtc atctgcgtca aattcatttc
    30061 gattagcgta tacccatgtt cctgccatac ctcgcatgaa atctcctaaa gcagaagaag
    30121 gaatacctcc accaggtgcg ggtgttcccg gactaggaag tggtacttgc ggctgcagat
    30181 gctcatcggt ggaatcaata gttgacaagc gttttttctt cgtttccttc tggtcatctg
    30241 attccttctg atcttccgac tgtttagcaa caaattcttt ttctgattgt tgttttattt
    30301 taggctctaa aatttcattt tccaatccag aaacttgtgg ggccaaatga gcttcttgcc
    30361 ttatcgtttt attagattct gagatttttc tagatattct tgctaactct aggcttcttg
    30421 tttgttttac tttccctgtt ggagaaactg catgagccat ttgttgtttt ttttctgaca
    30481 agctttcttc ttgtcttttt tgttcttttt gatctatctg tttgtttaat ggtaaaacat
    30541 gtaatagtga ctgagcatgg agttcttgga gtgaatacgg gtcatgataa ctatacataa
    30601 tcgtaaaatc acctgtttgt ttggtcaaat aaccatcctc caatggtact tcattgattg
    30661 taaccgatac atcctttaac ggtacgggtt tacctaagga atttgttgct gattggatca
    30721 actcttcttt gtttattttt tcgtttggat gaacaataag atcatgacct tctaatgaac
    30781 gattgtctgg tatataaaca taagtaaagg taatttcccc tcctgattgc ttcctattat
    30841 tcatcagttc tgagtgaagt acttcaagga tctccgacca gtgacttttt ctgtctaatc
    30901 cgtttgcttg catccaatca gaaatagaag tgactttccc attttgttca taagtcgata
    30961 aatctatatt tggcactcga tcagaaaatt cagcaggtag gcgcaaatca ggaatacgat
    31021 ttacactact catatgtgtt tctgcttgaa gttctttatt tgtttgacta tctataaaat
    31081 gagtgatgac agtcgatgaa gcagcagatg cttctacata aactacagct gttgtttctg
    31141 ccacatttga tgttttcgag tctatataag ttaatacaac gggatattct cccggagttg
    31201 tagtatctac tgtcccgttc attttgattt cttctttatt tcctgaagtt ccatcgcttt
    31261 ttgttacata ttcaacaaga tctttagggg cgtaactctc tcctgttctt aagtgaagat
    31321 cttttccttt gatagctgtt tgatcagcac gaacatggat cacagcagat gcagtcattg
    31381 tttttaaagc aattggatca aaataggaca aggaaatagt agatgttcct gtattagtcg
    31441 tatccacgat attcccattg tttgaaatta ctttggacat atctccttgt gttccatctg
    31501 cgttcttcag cctttctacc agatcagata tcgaaacttt tgtccctgcc agaacatcga
    31561 ttttctttct ttcaaactgt gaataatctt tttcatatac ataagaaact tgtgcgcttc
    31621 caccgtcctt tatatctgtc aaagcatgat tcaaaatatc agtgatctgt tttaactgat
    31681 caccttttgt aggatcagtc atatcggaaa agatagaaag cggcacactg cttccggttt
    31741 ccgatgtcca taatgttttg ttaggaatta accagtagtg gtttatcgtt ggaggataac
    31801 tgactttatt ataggaagtc aatgcaggaa gtagctgttt tccatttgca tcagtgaaag
    31861 tatgagtaat agtgataggg gaatcagtgg tctcagaaac agaggtacgt acgaccttga
    31921 tggtttgtgt cgttgcctga acgggtacat gcatatagac acctacagat aaactgatca
    31981 gcatcgtgcg catcataaac ttaacgtagt gtttttcaga acacgaccgt tccttatcta
    32041 aacgacaagc gtgtttattt agttgttttg aacgtctttt tgaacacatt tattcttagt
    32101 cctccctact cttgtctaaa catgaagtag taattttcat aagatgattt cattatataa
    32161 ataaaatcaa aagaagatgg actattagga gagtattttt tttgattttt tattgtttca
    32221 agaaaatcgg aataataact tatgtacttt ttaattttgt taagtaatat atctagttat
    32281 atctagttat atctagttac cttttctttg aaaaaaacat aaatcagcta ataaatatgt
    32341 gagacaaagc tgccatccat aaatactagc tgattttttc agttaaatgt ctattttttt
    32401 ctctgatgat ggtatttcca aaatattccc agtcatctgg agtcggtgga tttttccaaa
    32461 ttatctgttc tttattaaat ttttcaagta aacaatcaga taaataaata ttcgtacgag
    32521 aagtgattcg actctcaatc acaatattgt aatttttaaa tcctttcact tgagaaataa
    32581 tgtaatcggt ataagcagat ccttgcgaaa aatcaataca gacatgaatc ggtgcttcaa
    32641 aatatgatac cggacaaata ccgaccaata aaaagagata atcataaaat aagcgaatca
    32701 tgaaacgttc atcttttccc aagaaatagc gtttattctc ttgtatgacc ttttggattg
    32761 ctgtactgaa tattggatac gtctcgaaga aaaactgtag ctgcttttta gacgtaaagc
    32821 tagtcatctc aaagtcgaat atccaatttt ttcgattgac atgcatcata cccatacgaa
    32881 gttcttttcg tatatatagt ctttcttctt cagagatttc aatcgaaaat ggtaattgat
    32941 caatcaattc cactgacatt ttttgactaa tcatgtggat atcatgaaaa tgagcttccg
    33001 caagtccaaa tgcgccatct aattcaaatt cttcttccgt gatcaaaaac aacatgatat
    33061 aagaaatctc atcaatgatc tgctctttag ggatatgaag aaaagaaata tgtgataaat
    33121 ccttgatgat cttcattcct tctgagctct taaagtattc atctgaaaag aaacgttttc
    33181 cgattggttg attcccatag gccctcaaca aactaatagt ggttagcaaa ttgaatttga
    33241 ttcgttttgt tgcagacagt tttaaattga acagatattc aaaatattgc acgatactct
    33301 ttgcttcatt catgacgctt tctctaaatg gcatagaaaa accattaaag accccgaaat
    33361 ataccccaaa taatacgttc cgtatgttta tttcttcccc aactaatatg tttttcttta
    33421 actttatttg atgctgttca agaaaagaga ctaattctct tctttttaca taggctcttg
    33481 atatgcttaa aaaatgattc tctgcaaatt tttcgatcgt tacttttgaa tccacgatct
    33541 ccgttaacag tcgagcaatt tttgatcgtt gaaagtagat tcttcttaaa tttttgatat
    33601 ccgtcaaatt cagacgttcg acatggatct ctgcttcttc tgaaatttgg atctctggct
    33661 ttgttttgaa ttcagtaaat tctttattta attctatgat ataatttctt gttttaaatt
    33721 tagacaaacc taatgtttca tataacttag gcagcactac ataattcttt ttctcaaatt
    33781 ctaaatatct agctagcagc agtttttctc tatcttcctc ttctataagg taatccaact
    33841 tcatatccta cacctcaaaa aatgcctcat accaattact tgatatgcag atgaaagttc
    33901 atcttttcac ctatactgat tttatgatgg attatgcttg ttttttcatc agttattctc
    33961 attttttatc ttttttttga gaatattgca aaaaatggaa aaatttatga ggaaatattc
    34021 tatatttttt gttttattgt gttaaaatgt acaagatttg cgccatttgc gtaaacaacc
    34081 acaaaaaaga gcaggacggc caccgtcctg ctcttttact tattttaagt tccattactt
    34141 attaattggc taaacttctg cttgtttctg atattgcttg tttttctcca atgatccgca
    34201 cttctgtttc taaagacaca tcaaattttt ctttgattac ttcttggatg tgcgcaatca
    34261 attcaatata atctgtcgct gtcgcatgat cgatattgac gatgaatcca gcatgttttt
    34321 cagagacttg tgcaccgccc catttcaggc cttgcaatcc tgcttgttgg atcagctgac
    34381 ctgtatagtg tcctactggg cgcttaaaga cacttccgca tgaagggtat tctaatggct
    34441 gttttgattg acgcaattcg gtcaactcat ccattcttgc tttgattgct tcataatccc
    34501 ctgtttgcaa actgaatcga gcttccaata cgatagcacg taattcttgg actttactgt
    34561 gacgataaga aaataccatt tcgtcttttg tcaaagtttt caatgttcca tcttcaagca
    34621 aaagatccac ttcagcaaaa acatctttga tctctccgcc atacgcacct gcattcatat
    34681 aaaccgctcc accgacactt cccgggatgc cgcaagcaaa ttcaaatcca gtcaatgatt
    34741 ctgccaaagc tgcataagtc gtatcaatca gtgaggcacc tgcttccgca atgaccatcg
    34801 ttcctttgac atgaatctgt ttcatttcag tcagcatgat gactacaccg cgaatcccgc
    34861 catcttgaac gatcagattg cttgcatttc ctaataccat ccaaggtata tcatggattc
    34921 ggcaataatc gatgatttgc tttacttctt cttgtttttt cgggaatgca aggacatcag
    34981 ctggtccacc tgttttcgta aacgtatagt tcatcaatgg ttcatcaaac aatatagtaa
    35041 tcgtggctaa gctttcaact atttcttctt tattcactga ggattttcct ttcttttctc
    35101 aaacgtcctc attattctat cacgcttaat acaatcttgc cagtcttgtt caaagttgat
    35161 gacggtagtg atctttaagc acttcctcac ataattcatg acttcttaca acttcttttt
    35221 gtttaagcaa ttctgtttcc gatttaccta aacggatctg agaaaagaag gcctctacca
    35281 ttggctcaaa cccgcgtttg actagcgtgt ttgtccagtc gccaaattct ttcacttttt
    35341 ttccatcagc atcttgaatg acaagctggg tcagatcgtt tacttcataa gtaccatttt
    35401 tacttgttac ttgatatttt tctatattag cgccacttgc taaatccatc gttaaaatag
    35461 ccgtttgatt ttgtgtttct aattgtaaaa tggcatattc caaaaattcc tttgtttctc
    35521 ttatctggta ttttgttctc aaaatgggtt catctaataa atacacagct gtatcaataa
    35581 gatgtaaaaa caaatcataa aggacgaact ctgtcgtttc ttttgccgct attcgatttt
    35641 tttgcaggtg gatcaaccgc ttatctggga tacgtttcaa ttcttctacc ataggagcaa
    35701 agcgccggtt gaaaccgatc atcaaaatta tttggttctt atcagctaat tcttgcaatt
    35761 cacgaacttc atttagatgg acactcagtg gtttgtcaat ataaacatgg ataccatttt
    35821 ctagacattt tttggctaat tcataatgta cttttgttgc tgcgtggatc atacatgctt
    35881 cgattttttc ttctaaaagc tcatcgatcg tttcatatag atgttggaac ccgtactctt
    35941 tttgaattct ttcttttgtt tctttatttc ttgttgcaaa ataaaaatca agtgttcctt
    36001 gttttttcgc ataagttggt aaatatgctt tttctgcgat attccctaca ccgattacac
    36061 caatcttcat ctactttcct cctggatcat ttagttactt tcatcttaca ccatttttta
    36121 ctaaaatgag gtacaatagt atcgcaaagg taaggaaatt aattcgaagg agtgtgcttt
    36181 tattgaaatt tatctcttgg aacgtaaacg ggcttcgtgc catcgtaaat aaaaattttt
    36241 tagaagtttt tcatgagtta gacgccgatt ttttctgtct gcaggaaacg aaactccaag
    36301 caggacaaat tgatttagat cttccaggtt attatcaata ttggaattac gcggaacgaa
    36361 aaggctattc cggcacagcg atttttgcta aaaaaccagc attgaatgcc acttacggaa
    36421 tgggtatcga tatccatgat acagaaggcc gtctgattac tttggaatat tccgatttct
    36481 ttcttgtaac ctgttacacg ccaaattctc aaagcgaatt aaaacgttta gattaccgat
    36541 tagaatggga agaagccttt tataattatt tggaaaatct aaaaaaacaa aaaccagtca
    36601 tcgtgtgtgg ggatctaaat gtcgctcatc aaaagattga tttgaaaaac tggaaaacga
    36661 atcaaaaaaa tgctggattc actccagaag aaagagcggc tctttctcga ctgttggata
    36721 acgggtttat cgatacattc cgttattttt atccaaccca ggaaggtgtc tactcttggt
    36781 ggaactaccg attcaattca aggaaaaaca atgctggttg gcggatcgat tactttttga
    36841 cgagcaaaga tttagagcca ggactagctg atgcaaagat ccatacggac attatgggca
    36901 gtgatcattg tccagtagaa ttagatttga aataaagagg ttgtgaaaaa gtcgtttagt
    36961 ttcgagtatt aagaaaaatt ttgtgaaaat ggctttccac attttgcata aatttggcat
    37021 aataccgaga aactggcttt tgaacactgt ttatcgagag attgtgaaaa agctgtcctg
    37081 catcaagtaa taagaacagc caaacaaaaa tagttcctca tatttttcgt ttggttgggc
    37141 ttattaccgc agatacaagc ttttgaacac cgtttattaa gaggttgtga aaaagctgca
    37201 ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatattttt cgtttggttg
    37261 ggcttattac cgcagatgca agcttttgaa caccgtttat taagaggttg tgaaaaagct
    37321 gcactgcatc aagtaataag aacagccaaa caaaaatagt tcctcatatt tttcgtttgg
    37381 ttggacttat taccgcagat gcaagctttt gaacaccgtt tattgagaag ttgtgaaatc
    37441 agcgtcctga cctgagtatt agagaaacaa atggcaaaat agttcctcat attttgctat
    37501 tttttgagct aataccgagg gtcagctgat tgaacaccgt ttagtggaga agttgtgaaa
    37561 aagtcgccta ctttcgagtc gtaagaaatt tttttgaaaa tggttcctca caactttgca
    37621 taaatttgac ttaataccga gaagtcatga tccccatcta actccaaatc acaaggaatg
    37681 agttcaaaaa ctagcttttc tcaacaaata ttacataaaa aattctatgt tttttgttaa
    37741 atttatttgc ttttttcaaa agtatgttac agtaatttcc caaggaggtt ttacagaaat
    37801 gaattttgtt gccatggatt ttgaaactgc caatcatcag ccttatagtg cttgttctct
    37861 tgcgctagtc atggtaaaaa atagccagat cgttgatgaa ttctatacat tgatacagcc
    37921 tgagactcct tttttctggc gaaatgtcca aattcacgga atccatcaag aagacgtacg
    37981 caatgcgccg aaattcccag aagtctggca aactatccaa ccatattttc aaaaaaatcg
    38041 tttagtcgtt gcacataatg ctgcttttga tacaaaggtc ttagcgggat gcttagatta
    38101 ttatcatctt gaacagccta attatctttc tttatgtaca gtgaaaagta gccgtcgcct
    38161 gtttcctgaa tttccaaatc atcgattgaa cactgtgtgc gaaaatttga acatccaatt
    38221 agatcatcac catgatgcat tggaagatag tcgtgcatgt gcggaaatcc tgctttatca
    38281 agaaaaaaaa ttcgggacag atccattgaa aaaacttgtg actataaagt aaaagaatac
    38341 ttatgaaaca cacaaagagg tcgtgagcct gccgtttcac tccgagtcac aaggagcaat
    38401 ttcaaaaaat agcttctcat gtttattaaa tattgtgact ggtgaccgag gagctggcag
    38461 gagaacaccg tttattggag aggttgtgaa aaagctgttc tgcatcaagt aataagaaca
    38521 gccaaacaaa aatagcttct catatttttc atttggttgg acttattacc gcagatgcaa
    38581 gcttttggac accgtttacc
//
LOCUS       DACBZK010000018        36914 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.018, whole genome shotgun sequence.
ACCESSION   DACBZK010000018 DACBZK010000000
VERSION     DACBZK010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.018"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            533..1081
                     /gene="aac(6')"
                     /locus_tag="IVD66_001011"
     CDS             533..1081
                     /gene="aac(6')"
                     /locus_tag="IVD66_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAP6145249.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            1627..3288
                     /locus_tag="IVD66_001012"
     CDS             1627..3288
                     /locus_tag="IVD66_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6145250.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(3358..3705)
                     /locus_tag="IVD66_001013"
     CDS             complement(3358..3705)
                     /locus_tag="IVD66_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HAP6145251.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            3789..4730
                     /locus_tag="IVD66_001014"
     CDS             3789..4730
                     /locus_tag="IVD66_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6145252.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            4731..5774
                     /locus_tag="IVD66_001015"
     CDS             4731..5774
                     /locus_tag="IVD66_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6145253.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            5780..6850
                     /locus_tag="IVD66_001016"
     CDS             5780..6850
                     /locus_tag="IVD66_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6145254.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            6840..7793
                     /locus_tag="IVD66_001017"
     CDS             6840..7793
                     /locus_tag="IVD66_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6145255.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            7805..8815
                     /locus_tag="IVD66_001018"
     CDS             7805..8815
                     /locus_tag="IVD66_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP6145256.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(9100..9921)
                     /locus_tag="IVD66_001019"
     CDS             complement(9100..9921)
                     /locus_tag="IVD66_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAP6145257.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(10018..10296)
                     /locus_tag="IVD66_001020"
     CDS             complement(10018..10296)
                     /locus_tag="IVD66_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145258.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            10564..12573
                     /gene="metG"
                     /locus_tag="IVD66_001021"
     CDS             10564..12573
                     /gene="metG"
                     /locus_tag="IVD66_001021"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HAP6145259.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(13052..13639)
                     /locus_tag="IVD66_001022"
     CDS             complement(13052..13639)
                     /locus_tag="IVD66_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145260.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            13814..15136
                     /locus_tag="IVD66_001023"
     CDS             13814..15136
                     /locus_tag="IVD66_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6145261.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            15291..16067
                     /locus_tag="IVD66_001024"
     CDS             15291..16067
                     /locus_tag="IVD66_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAP6145262.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            16060..16629
                     /gene="rnmV"
                     /locus_tag="IVD66_001025"
     CDS             16060..16629
                     /gene="rnmV"
                     /locus_tag="IVD66_001025"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HAP6145263.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            16622..17506
                     /gene="rsmA"
                     /locus_tag="IVD66_001026"
     CDS             16622..17506
                     /gene="rsmA"
                     /locus_tag="IVD66_001026"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HAP6145264.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            17957..18586
                     /locus_tag="IVD66_001027"
     CDS             17957..18586
                     /locus_tag="IVD66_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145265.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(18710..19819)
                     /gene="ugpC"
                     /locus_tag="IVD66_001028"
     CDS             complement(18710..19819)
                     /gene="ugpC"
                     /locus_tag="IVD66_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HAP6145266.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            20028..20450
                     /gene="mgsA"
                     /locus_tag="IVD66_001029"
     CDS             20028..20450
                     /gene="mgsA"
                     /locus_tag="IVD66_001029"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HAP6145267.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            20773..21309
                     /locus_tag="IVD66_001030"
     CDS             20773..21309
                     /locus_tag="IVD66_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAP6145268.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(21349..23112)
                     /locus_tag="IVD66_001031"
     CDS             complement(21349..23112)
                     /locus_tag="IVD66_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6145269.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(23115..24830)
                     /locus_tag="IVD66_001032"
     CDS             complement(23115..24830)
                     /locus_tag="IVD66_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6145270.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(25609..25833)
                     /locus_tag="IVD66_001033"
     CDS             complement(25609..25833)
                     /locus_tag="IVD66_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145271.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            26033..28801
                     /locus_tag="IVD66_001034"
     CDS             26033..28801
                     /locus_tag="IVD66_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6145272.1"
                     /translation="MLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNTVSH
                     YLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQPKDL
                     FSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLHDLL
                     EDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLDEVH
                     RLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRIPIR
                     IELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGELKNI
                     VKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLMEKQ
                     QPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHELLVY
                     WTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELEQQV
                     SQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIAAHG
                     YATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILVDMG
                     SLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPEWRL
                     LYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNSDPL
                     FSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQRII
                     RNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLIERL
                     IRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSEDTE
                     FLSIEEEF"
     gene            28882..29301
                     /locus_tag="IVD66_001035"
     CDS             28882..29301
                     /locus_tag="IVD66_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HAP6145273.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            29313..29783
                     /locus_tag="IVD66_001036"
     CDS             29313..29783
                     /locus_tag="IVD66_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6145274.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            29800..30579
                     /locus_tag="IVD66_001037"
     CDS             29800..30579
                     /locus_tag="IVD66_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6145275.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            30566..31387
                     /locus_tag="IVD66_001038"
     CDS             30566..31387
                     /locus_tag="IVD66_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP6145276.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            31404..32453
                     /locus_tag="IVD66_001039"
     CDS             31404..32453
                     /locus_tag="IVD66_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP6145277.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYIQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            32466..33470
                     /locus_tag="IVD66_001040"
     CDS             32466..33470
                     /locus_tag="IVD66_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP6145278.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            34103..35122
                     /locus_tag="IVD66_001041"
     CDS             34103..35122
                     /locus_tag="IVD66_001041"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAP6145279.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            35165..36046
                     /gene="galU"
                     /locus_tag="IVD66_001042"
     CDS             35165..36046
                     /gene="galU"
                     /locus_tag="IVD66_001042"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAP6145280.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            36346..36723
                     /locus_tag="IVD66_001043"
     CDS             36346..36723
                     /locus_tag="IVD66_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145281.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
BASE COUNT        12130 a         6440 c         7561 g        10783 t
ORIGIN      
        1 gttgaaacgg gttaaaattt taaagagtga tcgatctgac tgcggctgta gatggagtag
       61 aggtgaacct aagacaggat aagtgatgaa taaggtggca tgaacacctt gaaatcatca
      121 ataagtatcc taaaaacgaa caagtacaaa aacattgaaa acgacaataa tgaatttttg
      181 ttcctcttag tatttctacc gattcccttt gcttttttgt aattatctaa aaattctaaa
      241 aattaagatt attatatgaa aacaggtttt atttgtcaat tcataattgg ttttttttaa
      301 agcaaaagat aatctatatc atgatgaaca aacagagttt tttcctccaa ttgatggctt
      361 tcctgatctt tcctattttg aataaagtgt ttctgtataa tttttttatt ttataagtaa
      421 gataaataat gaaagaatag agatactgat tggtagctaa agatttttga gcgagaacat
      481 ttcgtttttt caaaaggact gttagaataa gcaagaacaa gggggaagac gtatgataat
      541 cagtgaattt gaccgtaata atccagtatt gaaagatcag ctttctgatt tactgagact
      601 gacttggccg gaagaatatg gagacagctc ggcagaagaa gtagaagaaa tgatgaatcc
      661 agaacgaatc gcggtagcag cggtagacca agatgagtta gtaggattta ttggtgcaat
      721 ccctcaatac ggtatcacag gttgggaatt gcatccatta gttgtagaaa gctcccgacg
      781 aaagaaccaa ataggtactc gattagtcaa ttacttagaa aaagaagtag cttccagagg
      841 aggaatcacg atttatttag gtacggatga tttagaccat ggaacaacgt taagtcaaac
      901 ggacctgtat gagcatacat ttgataaagt ggcttccatc cagaaccttc gtgaacatcc
      961 gtatgaattc tatgaaaaat taggttataa aatcgtaggt gtcttaccaa atgcaaatgg
     1021 ctgggacaaa ccggatattt ggatggcaaa aacgattatt cctcgaccaa attctcaata
     1081 ataaaaagag gttgtgacag aagtaatcag cttcaagaaa taagaaggaa tttacgaaaa
     1141 ttacttcttg aatttttgtg aaattccaac ttatttccga agaagctact tttggaacac
     1201 cgtgtaccag aggttgtgaa aaagtcgctt agtttcgagt agtaagaaaa attttgtgaa
     1261 aatggctttc tacatttttg cataaatttg gcttaatacc gagaaactgg cttttgaaca
     1321 ccgtttattc agataaggga ctgtgacaag acttttgtca cagtttcttt ttgtttattc
     1381 ttttttatct ttgtatggca ataatagaca atataacgaa aattatttaa tggcttttgg
     1441 aagaccatgg aaaaccttgt acaaagctat tttttctgaa aaattccttg aaacctcacg
     1501 aaaaaatcat tattttatga aaaagacaaa aaaaagtgtt gattttttaa taattattca
     1561 ttaaactctt aaacaacttc agaaaatatt aattattctg aaaattccaa taaaggggta
     1621 cgtaaaatga aaaagaaatt tacatttggt ttggttgcgg tatgcggcct tgtacttgct
     1681 ggatgttatg gcggcagttc agccacaagc agtagttcag caaaaagcgg ttcagcagat
     1741 ggaggaggcg tatttaactt agtcgtgcct caagaaatgc ctacagctga cttatcagtt
     1801 gcaacagata caatcagttt tacagcattg aataacgttt atgaaggaat ttaccgtctt
     1861 gatgaagaca gcaaaccaca gccggcagga gctagcgagt tggcagaagt cagtgaagac
     1921 ggattaactt acaaaatcaa attacgagaa gacgcaaaat ggtcaaatgg tgatcctgtt
     1981 acagcagcgg attacgttta tggctggcaa cgaacagtag acccagctac agcttctgaa
     2041 tatgcttacc tgtatgcgcc agttgaaaat gcagaagaca ttacagctgg aaagaaagat
     2101 aaatcagaac tagggatcaa agcagttggt gactatgaat tagaaatcaa attgacgaaa
     2161 caaacaccat atttccaata tctgcttgct ttcccatcat ttttcccaca aaaacaatcc
     2221 gtagtggaag aaaatgggga tgcctatgca tctgcaagtg ataaagctgt ttataatgga
     2281 ccattcacat tagaagattt tgatggacca ggaacagata cagaatggac ttataagaaa
     2341 aatgatcatt actgggacaa agatacagta aaactttctg aaatcaaagt cagtgtagta
     2401 aaagaatctt ctactgcatt gaacttattc aaagatggcc aagcagatga cgtgatcttg
     2461 tctggtgagt tagcacagca aaacgcaaac gatccagctt atacttctgt taaagaagcg
     2521 cggacaagct atatcgaatt caatcaacgt gaaaagaatt caccattcaa caatgtgaac
     2581 ctaagaaaag ctatttctta ttctatcgat cgtgaagctt tagtaaaaca agtactaggt
     2641 gacggatcag ttgtctctac aggattgatc ccatcagata tggtaaaaag tccaacaacg
     2701 aacgaagact ttgcaaaaga agctggaaaa ttagtttctt atgacaaaga taaagcaaaa
     2761 gaatattggg aaaaagcgaa aaaagaattg ggcgttgatt ctttagaatt tgatttgatg
     2821 gcttctgatg atgattcatc gaaaaaagta atcgaatatg ttcaaaactc aatccaagaa
     2881 aacttggatg gcgtaacagt caaaccaaca cctgttccat tctctgtacg tcttgaccgc
     2941 tcaacttcgg gtgattttga cgcagtacta ggcggatggg ctgctgacta tgcagaccca
     3001 agcagcttta ctgatttgtt tgtcacaggt aattcataca accgtggtcg ctggagcaat
     3061 gcagaatatg acgaagcagt taaagcagct tcatcaacag acgctggcga tgaacaagcc
     3121 cgttgggatg atttccaaaa agcaatcaag atcatctctg atgatatggg tgtcgttccg
     3181 gtgtaccaaa aagcagaagg tcacctagtg aatgaaaaaa tcaaaggtat cgttcaccat
     3241 gcggcaggcg cttcatggga ttacaaatgg acatacgttg aagaataatc gttaataccg
     3301 tgagcatgag aaaaaacgag gctgcggcaa atgtcgcaac ctcgttctca tattcactta
     3361 tcctaacaaa gaaaaaagca tgaaaatagc agaaagagca attagtattc cggcaatgat
     3421 cagccaaaag ctgtacatac cgtagctggc agacgagagc gaggaaaatt ctggtttttt
     3481 ctttcggttc cttgttcgtg caagatggac cgatcgctga aaatgatcga agaaacccga
     3541 agaaaagacc cataaaaaac cgccgataat cagaaacggc aatgaccata agaatagatc
     3601 attagataat tgaatgagtg taaaggaatg gttgatgaga ttttttatta aaataaccag
     3661 aatcagtaga aaagctactg cgtaggggat agattttttt ttcatttgat tgctccttta
     3721 tttttggttc attatctaat aatgtagcga aacatctgtc agaagtcaaa agctaggggg
     3781 aaacattagt gaatagttat atcaaatatg tattaaaacg tgtctttttc atgatcatca
     3841 cgctttggtt aattgcaaca atcacctttt tcttgatgca attgctgccg ggcacgccat
     3901 atacgaatca ggaacgtttg agtcctgaaa caatcgagat gctaaataaa caagtcggtt
     3961 tggataaacc agttatcgta caatatggga tttatctttc taatttgctt caaggagatt
     4021 ttggaatttc cttccaattt aaaaaccagc cagtcgcaca tttgttagct ggaagaatcg
     4081 gaccatcctt gcagttaggg ttacaggcaa ttatctttgg aacagtccta gggacgattt
     4141 taggaacgat ctctgccatg aagcaaaata catgggcaga tacatcttct acactcgtag
     4201 cgatattagg tcgttccatt ccaaactttg tatttgctgt tttattacaa tatatctttg
     4261 caatcaaatt acaagttttg ccaatcgcaa aatgggatgg ctttgtgtac acaatcttac
     4321 caacaattgc gttggccatg tcgccgcttg ctgactctgc tcggtttatc cgtacggaaa
     4381 tggtggaagt actgcatagt gattatgtgg aattagcaaa agcaaaagga ttgagccgtt
     4441 gggaaatcgc ctttaaacat ggtcttcgaa atagtttgat tccattgatg actttattag
     4501 gaccgttagc tgtagcattg atgaccggat cactggtggt agaaaatatc tttgctattc
     4561 ctggtatcgg ggaacaattc gttaagtcaa tcacaacaaa tgattatcct acgatcatgg
     4621 ctgtaacgat cctttactca tttatgctga tttttgttat tttgatcgtg gatctattgt
     4681 acggtctagt tgatccaaga attcgtgttt cagaagggag ccgaggataa atggaaatga
     4741 taccaaagcg ttatgaaaca gttgcagata tccctgcgga tgaatttctt ccattacaaa
     4801 aaaataccga agaagaacgt gaacagatta ctgcaccttc tttgaatttt atccaagatt
     4861 catggcgccg tttaaagaaa aacaaagctg ccgttatttc aatggtttta ctattggtca
     4921 tcattttgat ctctgtgatc acaatctttg tttctcctca tgatccaact gcccaaaacg
     4981 tggcttatat caatttgcct cctcgtattc cgggaatcaa tatcgatgga ttgaatggaa
     5041 aagcaatggt tggtggtgaa cttgttgata aatatgctca agcaaacgtc ccttcaaacg
     5101 taaatttctt tttaggaaca gacggtttgg gacgtgatgt attaagccgc ttatttatgg
     5161 gaatgagaat ctcgttgctg atcgcattta ttgctgcatt actagatgta acgattggtg
     5221 tagcttacgg gttggtttct ggtttgttag gcggacgtgt cgataacgtg atgcaacgtt
     5281 ttttggaaat cttatcagga attccaaacc tcgttgtcat gattttgatg ttggtcgttt
     5341 ttgaaccagg aattttttca atcgtggctg ctatggccat cacaaactgg ataccaatgg
     5401 cacgtatcgt tcgtgcacaa acaatgaaat taaaagatca agaatatgtt ttagctggat
     5461 tgacattagg tgaatcaaga atgaaaattg cattcaaaca tattttgccg aatatctcta
     5521 gtgtcattat tattcaaatg atgtttagta ttccatctgc tattttcttc gaagcctttt
     5581 taagctttat cggtttaggt cttacgcctc cgtcagcttc attaggaacg atgttgagcg
     5641 aagggtacaa gacattcctg tatctgcctt atctattatg gattccggca gtaactttat
     5701 cggttatcat gattggcttt aacttacttg ctgatggatt gcgtgatgcc tttgatccta
     5761 aaatgaaaga gtgaagacga tgacgaaaat tttagaagtg aaagacttag aaatctcttt
     5821 tgatacgtat gctggaaagg tacgagcgat tcgcggtgtc aattttcatt tgaataaagg
     5881 agaaacattg gcgatcgttg gggaatctgg aagtggaaaa tcagtgacga ccagaagcat
     5941 catgcgcttg ctgtcaagca acgccaatat agatgctggt caaatcctct ttaaaggtaa
     6001 cgatatcgtt ggaaaatcag aaagagagat gcaaaaaatc cgtggtaaag aaatagcgat
     6061 gattttccaa gatccaatga cctctttaga tccgacgatg cccattggga agcaagtcgc
     6121 tgagtccctt agaaagcata ataaagtttc aaaaaaagag ggacaaaaag ctgcattaga
     6181 attgcttaaa ttagttggaa tacccgaagc tgagaaacgt atcaacagtt atccgcatca
     6241 gttctcagga ggtcagcgtc aacggatcgt gatcgcgatt gcactggtat gttatccgga
     6301 aatcctgatt gctgatgaac ctacaacagc gcttgatgtg actattcaag cacagatttt
     6361 ggagctgctg aaagaaattc agacaaaaat cgatacatca attatcttta tcactcatga
     6421 ccttggtgta gtagcgaatg tcgctgatcg tgtcgctgtc atgtatggag gaagaatcgt
     6481 tgaagttgga acatcggaag aaattttcta caacccgcaa catccctata cttggggact
     6541 gcttggttca atgccgacat tagatagtgc gaacgatcga ttgtatgcta ttcctggttc
     6601 tccaccggat ttattgaacc cgccaaaagg agacgcattc tatccaagaa atgaattcgc
     6661 gatgaaaatc gatgcagaac aagaaccacc attttttgaa ctatcaaaaa cacacaaggc
     6721 agcaacttgg ctacttgctc cgcaggcacc caaagtgaca ccgccagaag aaatccaacg
     6781 tcgctgggct atctttaaag agaaacaaaa acatacttac ggtcaaggag gaattgctga
     6841 tgccaaataa actacttgaa gttaaaggat tgaaacagta tttcaatgta ggaaaaaaga
     6901 atgaagtaca tgctgtaaat gacatcagct ttcacattta tgaaggagaa acattcggtt
     6961 tagttggaga atctggaagc ggaaaatcca ctactggccg tacgatcatt cgcttgaatg
     7021 aacctactga tggtgagata ttattcgacg gtcaagatat aacgaagatc aaagataaaa
     7081 aaggtttgac gaaattccgg catgatgttc agatgatctt tcaagatcca tacgcttcgt
     7141 tgaatcctcg tatgaaagtc agagatatca ttgccgaagg aattgatgtt aatggactag
     7201 ctaaatcatc tgaagagcgt gcaaaaaaag tcgatgatct attgagaact gttggattga
     7261 atccaagcca cggtactcgt tatcctcatg aattttcagg tgggcaacgc cagcgtattg
     7321 gtattgcacg agcattggca gtaaaaccgc gttttatcat ttgtgatgaa ccaatttctg
     7381 cactagatgt gtcgatccaa gcccaagtgg tcaatttgtt gcaagatctc caaaaagaac
     7441 atcaattgac ctatctattt attgcacatg atttgtcgat ggttaaacat attagtgacc
     7501 gaatcggtgt aatgcataac ggcttgttat tagagatggg aacaagtgat gaaatctata
     7561 atcacggtgt tcatccttat acagaaagtt tgttatctgc tattcctcta ccagatccag
     7621 accatgagag aaaacgcaga agaatcaaat atcaacctga accagatgac ggacaagtac
     7681 gtcaacttcg tgaaatcgca ccagaacatt ttgtctatgc aactgagcag gaagtcccat
     7741 attacgcaaa aaaactaaaa cgacaaaagg aatctcttct ggttgctaac taggagggac
     7801 atagatgcta aaagctttta aattccgtat gtatccgaca gaagaacaaa aacagcaatt
     7861 gattcgtact tttggatgtg ctcgatttac ctataaccat ttgctgaaaa agcggcagaa
     7921 aagttggcaa caaacaggag tagccaattt ttcgctcaca cccgctacat taaaaaaaga
     7981 atacccattc ttaaaagaag tagacagtct tgctttagca aatgcacagc ttaatttgga
     8041 tcgggctttt cgcaattatt tcaagggacg tgccagcttc ccaaagctta aaacgaaaaa
     8101 aagtatgtgg caatcttata cgaccaacaa ccaaacccgt acgatctatc tggaaaatgg
     8161 ctacttaaag ttaccaaaac aaaaagaact aatcaagata aatcagcatc ggccagttga
     8221 aggatcgatt cgctccgcta cgatttctgc tcgatataat gaagaatttt atgtcgcact
     8281 actttgtgat gtttcgccag taaaaaaaga atctttagct aaatggatcg ggatcgccta
     8341 tcatccgaag acattgatcc aaacatctcg acctctagaa gtaactttac caaaatttca
     8401 ccagacagaa gaaaagctgc aacatgcaca gcggaaattg aatgtgaaag tccgctccgc
     8461 tcaccataga aagatcaggt tagatcaggc aagcaattat cagaaacaaa agagaaaagt
     8521 aatggatctt tatctgaaac aaaagaacca gcgagaagat tatcttgaac aattatctgg
     8581 gaaattggtc aaacaatatg actacttatt tgtagaatct tttccaaaag aagaggcaca
     8641 tgctgatttt tctattcacg actggcataa attaataaca aaattgcgtt ataagtccca
     8701 atggtataat aaaaaatttc ttttgatcaa taccgacgga gcagaagaaa gcaattccgt
     8761 aagaaagagc caagtagtag aaaaaatggg cagacattcg gttatcaagg gataaaaaat
     8821 gaatgaaact gataggagcg ttagggttag ccttgttaat aaaaagtctt aatgactttt
     8881 gtttctagga atttttcttt tgaagaaaag ctcactaatt atgacaaacc aataaaacaa
     8941 tagcagaaaa agttcgtacg agctttttct gctattgtta attttttatt cagaaagttt
     9001 acgaatacat caaaattctg aaacaaaaaa cgtaactcac aaagagttgt ttttgcgttt
     9061 tttcttgaat gattaggtct gaatcttttg ctcacaacct tattcatggt gccccggctt
     9121 gagctgatag atttttgaag gacggccgat tcctacagga cgttcaccga tctcatcgaa
     9181 atattggagc atagctttct taaaattgga atgatcgatc gttttataat cgatccctaa
     9241 gaatttagca aatacttttc gagcttccgt aatcgtgaaa tctttaccta aaacttgtag
     9301 aacttgcggc tcgtgttcca ttttattgac tacacggttg aatgctttca agatgatttg
     9361 actatggtca aaagccaaag tatctttgcc agaagactct ccagtgacta aatcaagcga
     9421 gatagccact tctccgctag ataaatggat cttgttacta tgacgttcta gtgtgaacca
     9481 gcgtacttcc ttggcatcat ctccggcgat tagcggttct tctccaataa aggctaagta
     9541 gctgactgtg acgacccagc ctcgcggatc tcgattaggc gtactgaatg tatgcagttg
     9601 ctcaatattt tcttttgaaa taaccacacc agtttcttcc tttgtttctc ttaagacgct
     9661 ttctccagtt gactcatcct tttggacaaa gccaccaggc aatgcccatg aatttcgata
     9721 aggatgccct tttctttgga tcaacaaaac tttcagctga tcttcttctt tgttatagca
     9781 catcagtacg atatcgacag tcaaagaggg cttgtcatat tctggacgtt cctgtttttg
     9841 ataccagtta agaaattctt cttcacttgc tttatgttca taatataatt tttcttcttc
     9901 tttagaagca aaacggttca tctgaccacc tccattgaca gtaaaagtac tttttacctt
     9961 attgtagcag actctgaaaa aaaaccaagg atttacttga aaaatctagg ttatcattta
    10021 aatatgaaaa ataaatggaa gtatgagatt gaataaaaag aaaagcagat aaaacggcaa
    10081 tactttatac cgctcttcac gaatggcaaa gaagccacaa ataacgatat atacgtcaat
    10141 gataaaacgc aaaatccaag ctgctgtcat aaaactgttc aaatgcccat ggaggttaaa
    10201 ataaccatac atacgaatat aaaaatagct gaatattaaa tgtgctaatg aaagaaaagc
    10261 aatactaagt gtaaaaaaaa gatgtttctt ctgcatgatt gttccagtcc cttactaaga
    10321 tagatagtct ttattatacc acgtgtgagg ggagaaataa aaagccgttt tttagtagat
    10381 atgaaacaaa acaaaaaccc gcatttattc aacctattca tccttttaaa ggatagattg
    10441 aacgtagata gaagtcgttt atccagtctt tttcattttg aaaaaaagct aacagcatgc
    10501 tttttttatg gtatactagc aaggaaacga attcgcatca tgcgataaag gaggaagagc
    10561 cccgtggcag aaaaggaaac tttttatatc actacgccaa tctattatcc aagcggcaaa
    10621 cttcatatcg gcaactcgta tactacgatt gcatgtgacg caattgctcg ttataaacgg
    10681 ttgatgggct ttgatgtgtt ttatctcact ggagtggatg aacatggtca aaaaatcgaa
    10741 acaaaagcag aagaactagg tgtaaaaccg caagaatatg tagataaaat ggcggctgat
    10801 gtcaagaaat tatggaaaac gcttgatatc agttatgata aattcattcg cacgacagat
    10861 gattaccata aagcagctgt tcaaaaaata tttgatcgtt tattagaaca gggagatatt
    10921 tacttaggtg aatatgaagg ctggtactct gtttctgacg aagaattctt tacagaaaca
    10981 caacttgcag aagtgtacaa agatgacgaa ggtaacgtga tcggtggtaa agcgccaagt
    11041 ggacacgaag tagaattggt aaaagaagaa tcatacttct tccgcatgag caaatacgca
    11101 gaccgtctat tggaatacta tgaagaacat cccgaattca tccagccaga atctcgtaaa
    11161 aacgaaatga tcaacaactt tatcaaacca ggattagagg atcttgcagt ttcacgaaca
    11221 acttttactt ggggagtacc agtcaagagt gatccgaaac atgtggtgta tgtatggatc
    11281 gatgcattat ccaattatat tactgcacta ggatatggct ccgaagatga aagtctattc
    11341 gaaaaatact ggcctgcaga tgttcagatg gtcggtaaag aaatcgttcg ctttcatacg
    11401 atctattggc caatcatgct gatggccctt gatttgcctc tacctaaaaa agtatttggg
    11461 catggctggc tattgatgaa agacggaaaa atgtctaaat caaaaggaaa tgtcgtttat
    11521 cctgaaatgc ttgtggaacg ttatggttta gatgcactcc gttattattt gcttcgtgct
    11581 gttccgtttg ggtcagatgg tgtctttacg ccagaagatt ttgtttcccg tgtcaattat
    11641 gatctggcaa atgatctagg gaacttattg aatcgaacga ttgctatgat caacaaatat
    11701 tgtgatggac tcgttcctga ctatgcctca cttgtcactc catttgatag tgaactgtct
    11761 acgacggctg ctaacgttgt cggacgttac catgatgcaa tggaaaaaat ggaattcaat
    11821 acagcattgg ctgaaatctg ggtgctgatt tctcgtgcaa acaaatacat tgatgaaaca
    11881 gaaccatggg tattagcaaa agacgaagaa aagaaagctg aattgaatag tgtcatgatc
    11941 catttagctg aatctttgcg tatcgcagcg atattacttc agccaatcat gacagaaacg
    12001 ccagagaaga tcttcaatca actaggattg gactctgaaa caatgaatct tgaaggatta
    12061 cactttggcg aatttccttc aggaacaaaa gtagttgcaa aaggtacacc aatcttccca
    12121 cgtttagata tggaagaaga agttgctttt attcaagaaa aaatgtctga aggtactcaa
    12181 acaaacgaag atacagtcaa atgggatcca gaagaaacag aacttgtttc aacgaaagaa
    12241 aaacaaatca aatttgatgt atttgaaaaa gtagaactaa aagtagcaga agtcatcaac
    12301 tgtcaaaaag tagaaggggc agataagttg ctgcaattcc gactagatgc tggagacagc
    12361 caagaccgtc aaatcttgtc aggaatcgct gaattttatc ctgatccaag cgaattgatc
    12421 gggaaaaaag tcgtcattgt agcaaatctg aaaccacgaa agatgcgtgg acaaatcagt
    12481 caaggaatga tcctttctgc agaagcacca gatggctctt tacaagtaat cgaagcacca
    12541 aaatccatgc caaatggctc agaaatcgca tagaaattca aagggggtat gacactagtt
    12601 gtgtcatacc ccctttttcc gaaatttgag aagcaatttt cgtaaattcc ttcttattac
    12661 ttgaagccaa tcatataata cagaaacaga gaactatcca aaataaatcc tagaaaaaga
    12721 agtacgagct tcgctgattt ttgttaattt agaataatac taataggaat cgtaaaaaca
    12781 gaaaaaaagc ataatgataa agggtcgggc agattttaat tgattcatct ggtactcttt
    12841 tttattgtcc ttacattcat aaagtttgaa tgcaatgact ttattacatc tatatttata
    12901 tctaacagta gcgttgatgt gttaattata agttctatca ctttatgttc aattagtttg
    12961 tgctcttata tgtgtgattg aaaatataga taaaaaaaca atcatcggct ttgacttcga
    13021 tgattgtttt ctttattttg taaaaatcct atcacttgat tttatggtaa ccttttattt
    13081 ttgtcttcaa acggcttggt aagagagcag taagcagtgc aaatgggatc gaaaagacat
    13141 accagaaaat cgtacgtccg ataccataat gttgatagag ctttgtcaac atcacgtgta
    13201 acaagatcaa ccctaaaagc aaggagccag ctataaacca atgattatcc caatgcatga
    13261 cttcactaag tgccatcact ccaaaaggat agaaataaaa atagatcccg actaaggtca
    13321 tccgccagtt ctttgtaaat gttccgatat tcaataaaaa gaaaatcgct gaaagcaaaa
    13381 taccgatagg cggaaaaagc ccaaccaaaa aggaatacaa catcccccac aagatcatca
    13441 caggaccttt gatcaatgca acgattgcga tgaacaaagt cagcaatatt agtttttgtg
    13501 ataacgttgc aacagtcatt aatccaaata aaattaatgt gaaccaatgc caatgggact
    13561 gctgttgttc tttacgggaa aaatcgaccc ggttggataa ataatctgct aatttcggat
    13621 aagaacgctt aaaatccata aactgttcct ccttcgtgga aaaggtaggt ttagtatacg
    13681 aaaaataaaa aagaaataca tccgtcttaa gagggagttt ttcactgaaa gtggagaaaa
    13741 aagaatggta aattaaaata ttctcagtta tactgaaaat tataccaaat ttcaaagaag
    13801 aaagaggatg ggaatgaaag gcaaactaaa acgagaaatc aatctgtttg gcgcattagc
    13861 taccgttatg ggaaccgtga tcggtgcagg cgtcttcttc aaaactgctg ctgttactgc
    13921 tagtactcag tctacaagtt tgacattgct agcttggctt ttgggtggtt tcttaacgat
    13981 ctgtgctgga ttgacagtgg ctgaattagc tacagcaatc ccggaaactg gtggagctgt
    14041 aaaatatatt gaagctgcgt atggaaaatt gcccagcttt ttattaggat gggcgcaaag
    14101 cttgatttac tttcctgcta atattgctgc attatcgatt atctttgcga cacaattgac
    14161 gaacttatta caattatcta ccgattatct tttgttgatt gcagtgatca ccgctgtttc
    14221 tgtgacaggg ttgaatttgt tagggacaaa agtcggtgct tctgtacaat cagtgacgtt
    14281 gattgttaaa ttaataccaa ttgctgtgat tgtcatatgg ggattattga ccccaggaca
    14341 aggaactgtc cagttatttc caatcgaagc tggaaaagat gttacttttg tcgaaggatt
    14401 gagcagtgcg ttgttagcaa cgttgtttgc ttatgacggc tggttaggtg tcggtgcaat
    14461 ggcaggggaa atgaaacggc cggaaaaaga tttgcctaaa gcaattattc ttggtttgag
    14521 ttttgtaaca gtcgtttatc tattgatcaa ttttgttttt ttgaaaactt tgccgattga
    14581 tcatcttgcc ggtaatttga atgcagcttc tgaagcatca gacgtcattt ttggaggaat
    14641 cggtggaaag ctggtcacta ttgggatctt gatctcggta tacggtgcat tgaacggtta
    14701 tacactaact gggatccgcg tgccttatgc gatggcttta gaagacgagc tacctttcag
    14761 taaacagctg acaaagcttt caaagaagtt tacggttcct tatgttcctg cggttttcca
    14821 gttagcagta gcttgtatta tgatgagcct tggttctttc gactttttaa cagacatgtt
    14881 gatttttgtg atgtggctat tcagtttact gatttttatc ggtgtcttta ttttaagaaa
    14941 aaaagcgccg gaattgccac gtccatataa agtaccactt tatccaatcg ttccgattat
    15001 tgcgattctc ggtgctattt tcattttagg tatgacgatg atgacgcaaa cgaaattagc
    15061 attgatcggt ataggtgtta ccttgatagg tatcccagtc tattatcaaa aaaagaaaaa
    15121 acgctcagaa gagtaaaata tttcaacaac agacagaaaa agtacgaact aggtcctcta
    15181 gatcttcgtg ctttttctat ttcaataaaa caagttcttc tattttgatt tttgctactt
    15241 ctgcaagtag tgcttatgtg ctaaagtaag aatgaaaagg agagataaac atgatatttg
    15301 attctcatac ccatttaaat gctgaacagt tcaatgaaga tattccagaa acgattcagc
    15361 gagcacaaga aatgggggta acgaaaatgg cggtcgtggg cttcgatacg ccaacgattg
    15421 aaaagtcttt gcaattaagc catgactatc caaatatata cagtattatc ggctggcatc
    15481 cgacagaggc tggcagttat acgaaagaaa tcgaaaataa attacaagaa caattgactt
    15541 taccaaaggt tgtagcatta ggggaaattg gcttggatta tcattggatg gaagacccga
    15601 aagaagtcca agataaagta tttcgcagac agattgctat cgcaaaagaa atgaacctac
    15661 caatcagtat tcatactaga gaagcacttg aagacacgta tcaaatccta aaagaagaag
    15721 atgttcgaga tatcggtgga atcatgcata gtttcagtgg tgattatgaa tgggcaaaac
    15781 gatttcttga cttagggatg catatttcat ttagcggtgt cgtcactttc aaaaaagcat
    15841 tagacgtcca agaggctgca gcaaatgtac caatcgaacg attacttgtg gaaacagatg
    15901 ccccttatct ggcaccagtt ccttttagag gaaagcgaaa tgaaccaggc tatactcgtt
    15961 atacagtaga aaagattgct gaacttcgga atcttccgac agaagaagtg gctgcccaaa
    16021 catggacaaa tgcgcaccga ttatttggtc taagcgaaca tggataagat gaagatccaa
    16081 gagattatag tcgttgaagg aaaagacgat acaagaaggc tgcgggaagt agttgatgca
    16141 gatacgatag aaacaatagg gtctgcaatc aatgaagaga tcctgatgca aattgaacat
    16201 gcccaagaga ctcgtggagt gatcgttttt accgatcctg atttttcagg agaaaaaata
    16261 agaaaaatca ttatggaagc tgttcctcag gcaaaacatg cttttttgcc gcgcacacaa
    16321 gctaaaccaa agaaaaaggg aagccttggt gtcgagcatg caagtgatgc tgctatttta
    16381 gaagcattga aaaaggtcgt gacgccagac atttcccaaa cggctgtttc tgaaatcact
    16441 agacaagacc ttttagacta tggtttaata gctggggcac aagcaaaaga aaaacgagaa
    16501 aaactaggtg acgagttgcg catcggttac acgaacggca aacaattgga aaaacgtttg
    16561 aagatgtttc gtattacgcc gaaagaactc gcccaagcaa tgaaaatagt ggaggaacaa
    16621 catgagtgaa tatcgtgaaa ttgcgacacc ctctagaaca aaagagattt tattgaaaca
    16681 tggtttttca tttaaaaaaa gtttaggaca aaattttctg actgaaccaa atattttaag
    16741 gaaaatcgta gaaactgcgc aaatagatga acatacgaac gtgatcgaag ttggaccagg
    16801 aatcggtgca ttgacggaac aattagccaa gcatgcaaaa caagtcgtag catttgagat
    16861 cgatgatcgt ttgatccctg tattggctga tacgatgcaa ccctatgaca atgtgactat
    16921 tgtacatcaa gatattttaa agaccgattt gtcaacagct gttagagaaa catttcatga
    16981 ggagcttccg ttaaaagtcg tagcgaattt accttactat attacgacac cgatcatgat
    17041 gcattttctt gaatcagatt tggttgtgga tgaactagtc gtcatgatgc aaaaagaagt
    17101 agctgatcgt atctctgctg aaccaggaac gaaagcttat ggttcattat cgattgctgt
    17161 tcaatattat atggaagcca gtttagcatt catcgtacca aaaacagtat ttgtccctca
    17221 gccaaatgta gattcagcga ttttgaaact gacaagaaga gatataccgg cagtcgaagt
    17281 gacagacgaa aaagcatttt tccgattgac aaaagcggca tttcagcaaa gaagaaaaac
    17341 gctttggaat aacttgcagc attcgtatgg caaagatgac cagacaaaag catggttagc
    17401 aaaaagcttg gaaacagctg gaatcgatcc aaaacgtcgt ggggagactt tgtcattaca
    17461 agaattcgcc gcattaagca atgcgatgtc agaaaatatg cagtaaaaaa agaggttgtg
    17521 acagaagttg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa caaaaatagt
    17581 tcctcatgtt tttcgtttgt ttgggcttat taccgcagat gcaagctttt gaacaccgtt
    17641 taagaaagag gttgtgggcc tgccgtttaa ctctaagtca caaggaacaa tttcaaaaaa
    17701 cagcttctca tgtttttgag ttagttggtc ttattacttg atgcaagctt ttgaccacta
    17761 ttatgccgaa caaggagatg tgacacaaat tttgtcacat ctcctatttt tgtttcttga
    17821 tcaaaaaatt cttatacttg atactcacac tcattttgta tggatttaga aaagaatatg
    17881 tgtcttgaca gttattagta agtgagttat actaagtcga catttatgtg tcaagacata
    17941 ttaggagaga gaaaaaatga gaaaaaattc agttcgaaaa ctaacgattt ctgctttatt
    18001 gattgggatg ggggtcatta tcccaatggt catgcctaaa atcatgattc caccagcttc
    18061 ctttactttg gcgtctcatg tgccattatt tattgcgatg ttttttacac caggagttgc
    18121 agtggctgtt gcgctaggta cgacatttgg tttcttttta acaacgccgg ttatcatcgc
    18181 attgcgagca ttgtcacatc ttgtgtttgc gttgattggg gcttggtact tgcaaaagca
    18241 tccgagtatc gttttaaaaa atggacagtt tacttttgct aattggcgtt tccaagggtt
    18301 caattttgtg atcggtgtga ttcattcttt agcagaaatg ctagtagtca gcatctttta
    18361 ctttattggt aatatgcctg aaacatatta ttctcaagga tatttttata cagtattcat
    18421 cttgatgggg attggtgggc ttatccacag tttagttgat tataatattg cttattttat
    18481 agcaggaaca ctcagcaaat attttgatat ccccgtattt acggcagcaa aaaaagaaaa
    18541 tcggaaagag tcgattcaag ggtacgcgaa gaaaacgaca tattagacat gatctctcaa
    18601 aaaaaaaact ctcatctagt aatggataat aaatcctcta agatgagagt tttttgtcct
    18661 aaaaagagct gcaccaacat cttctggcac agctctaaca gggggcaatt tatggaagtt
    18721 tgatgacttg ttctgtttct ttatcaaaga agtggccttt gctgatgttg aaggcaaggt
    18781 cgactatttc gcctggttta tggaaatctc ttgcatctac ttttgagatg aactcagtag
    18841 aaccagtttt tgtgtaaagc atcgtttcag ctccaagtaa ttcggaaacg acaacttctg
    18901 atttcactac ggcttcaggt gaagcttcaa gggctacttg ttcactgtgg atgtcttctg
    18961 gacgaatacc gaagataact tcttttcctt cataaccttt ttcaactaat actttgtttt
    19021 ttccttcagg aatacgaagc ttaagcccat gtccatctgt gataacacca tttttcaatg
    19081 tcacattaaa gaagttcatg gcaggagatc caataaagcc ggcaacgaac atattgacgg
    19141 gtgtatcata aacttctttc ggtgtaccga tttgttggat aaatccgtct ttcatgataa
    19201 cgattcggtc agccatagtc attgcttctg tctgatcgtg agtaacatag atggtcgttg
    19261 tttcaagacg ctggtgaagt ttggcaatct cagcacgcat ggctacacgt aatttagcat
    19321 ctaaatttga taatggctca tccattaaga agacttttgc atcccgaacg attgcccgtc
    19381 ccaatgccac acgttggcgt tgtccaccag ataaagcagc tggttttcgt ttcaagtatt
    19441 ctgtcagacc taagatctct gctgcattgt ccacacgttt tttgatgtct gctttatcat
    19501 atttacgtaa tttcaagcca aaagccatat tatcaaaaac agtcatatga ggatacaatg
    19561 cgtagttttg gaaaaccatg gcaatatcac ggtctttagg tgccacgtca ttcatgactt
    19621 ttccgccgat atttagttct ccttcagaga tatcttccag tcccgcgatc attcgcaaag
    19681 tagttgactt tccacaaccg gaaggaccaa caaaaacgat aaattcacgg tctttgattg
    19741 atagattaaa atcagttaca gaataatttt ctgcattgtc atatttttta tatacgtttt
    19801 tcagagccat ttctaccata atacgttcca cactttcttt tttagtttta ttaactattt
    19861 aaagtataaa tgaaagcgtt aactaacttc aatgtcatgt tgaacaagaa ttttttcttt
    19921 tttttgtcaa tgtgctagtt ttaagcttta ataaatatcc ataagaaata aaaactgata
    19981 cactggagta aataagtatg ttaacaatat caaaaggagt gtctcttatg aaaatcgctt
    20041 tgatcgctca tgaccgaaaa aaacctatga tggtgaaatt agcaacagcg tataaaacaa
    20101 tattggaaaa acatgaactt tttgctaccg ggacgactgg gcagaggatc acggaagcaa
    20161 ccggcttgcc gatccatcgg tttaaatccg gaccgttagg cggggatcag caaattggag
    20221 ccatgatttc ggaggatcag ttagatttgg tgatttttct tcgagacccg ctggctgcac
    20281 agccccatga accagatgta acagcactta tccgtttatc tgatgtctat gagattccgt
    20341 tagctacgaa tatcggaaca gctgaggtgc tactaagagg actggaagcc ggcttcctag
    20401 attttcgaag aatcgtccat gaaatagaca agcatccact ttcattttga tggataagcg
    20461 tatggaaaaa taacgtttaa tgttcgccta tatgtagcta taaaagctaa acaaactgat
    20521 aatatgcgat ataatacgaa cgtattggat aatataaaca ataatattag tttttcgtat
    20581 ttgcagtaaa tgtgaaaata tgctatagtt tctgtgggaa aagatcccaa aaataataca
    20641 gagtagaaaa taaagcgtta agtgctaaga ggatgggatg ttgcctcttg gacgaaggac
    20701 gtaatgttcg cggttttatt ttcgcattcg ctgcatgata cgatgtagca gctcttaaag
    20761 gagatgctaa aaatgaagaa acaccggtta gacgcacgta tgattgctat tatgggctta
    20821 ttgattgcat tgatggtcac tttgtcccga ctggtagcaa tcgagacccc atttattaaa
    20881 atcagtgtca catttattcc acaagtgatc atgggcattc tttttggtcc tttttggtca
    20941 gggataggcg cagttttagc tgatttagta ggaatggccc tcttctcgaa atctgcattc
    21001 tttattggat ttacattgaa tgcatttatt gaaggagcaa tctacggatt ctttttctat
    21061 cgaaaagaga tcacttggaa aaatgccatt ctggctacgc ttagtgtcac gctgatcatc
    21121 aacttatttt tgacaccatt atggcttgcg ttgatgtacc atgtgccatt gttcagctgg
    21181 gtcgtttggg cgccccgcct gttaaaaaca gtaatatggt taccgattca atcaattgcc
    21241 atttattacg taggacgtag tattccttac aaaaaaattt taagaagttt agcgatccac
    21301 gctaaataaa aaacaagcag tcttcccatc ccagaagact gcttgttttt attgtgctgt
    21361 gaattgtgct tgatagagcc gtcggtaata accatctttt tgaagcagct catcatgggt
    21421 gcccatttcg acaatagctc cctgatccat cactaatatc tggtccgcat ttttgattgt
    21481 ggacaggcga tgggcaatca caaaactggt ttttccttcc atcattgcta agaaggcttg
    21541 ttggattttt ttctctgtca atgtatcgac tgagctggta gcttcatcta agatcaacat
    21601 agggggatta ctgatcatcg ttcgagcaat cgtcaacagt tggcgttgtc catctgatat
    21661 ctttaaccct tgaccgccaa tcttagtatc taatttttcc ggcaaacgtt ctacaaattc
    21721 atacatataa gaggctttta gggcatcatt gatttctgcg tcacttgctt ccggattccc
    21781 aaaacgaaga ttttctcgca atgtactgtc aaatagccaa gtatcttgta acaccattcc
    21841 aaaactttta cgtaatgtat cacgttggat agagcggatg tcatggtcat cgactgtaat
    21901 tgttcctttt gttgtgtcat aaaaacgcat cagcaaatta acaagtgtgg attttccggc
    21961 ccctgttttt cctactatag caatggtttg acctggataa gcagtaaaat tgaaatcttc
    22021 gatcaaacgc tgcttggggt cataagaaaa agaaacatga tcaaaagaga cttttccttt
    22081 gatatttttg ggttccaagg cataggcatc tggcaaatca ggcttttctt ctggctgatc
    22141 gatcaaatca aatgctcgtt ctagaccaga aaaagcggtt tgcagttgtg tcgtgattcc
    22201 agaaagttcg ataaatggtt tagaaaactg acttgagtag atcgtaaagc tggaaatcac
    22261 accaacagtg attgacgaac cactcttcaa tgccaatagg ccgccaacta aaccaatcga
    22321 taaataagca aggtgatcta caaaacgaga agacgggttt gtcaaggaag aagaaaattg
    22381 tgcccgttgt cctttttcat atagatcagc atttagcagt tcaaattgct gttgactagc
    22441 ttcttcttgc tgaaaagctt tcacgatttt ctggttaccg attcgttcgg tcacaaagcc
    22501 cgagatatcc ccaataatcc tttgctgtct atcgaaattt gtttgtgaag cacgagcaac
    22561 gatccaactc acaaggaaaa taattggtgt agaacaaaga acgaccaatg tcagaagtgg
    22621 acttagacgc atcataaaaa taaacgaaag aatgatgatt gccactccag aaaataattg
    22681 attgaaggcc gcagaaattg caatggaaat attgtccata tcatttgtaa atcgactgac
    22741 gatatttccg tgggagtttt gatcataata acgaagtggc aatcgattca gatgagcaaa
    22801 tgcatctttt cttaattttg caacggataa gtaagctaac cgattgctta acacttggat
    22861 gagccattga ctgactacgt tgattaaaac gataccaccg aatagaataa gtaaatggaa
    22921 cagtcgattg aagcggacct gtccttctcc aatcatttga tcgatacttt gaccaatttg
    22981 taacgtcatc acaactgttg caatcccatt gatgattcct agtatcacag ctagccaaat
    23041 gtcttttgca taggcagtaa ggtaaggaat gaatcggcgg agcgtctgca aggataattt
    23101 ttttactttc ataactattc ttcctcctgt gatgcgacga tttcctgata ttctgctgat
    23161 tgagcaagta attcttcatg ggtaccctga gcagcaatct taccttgatc catcactaag
    23221 atatgatgtg cttcttgaat agagcggaca cgttgggaga taataatcac tgtactgcca
    23281 agataagtct gtagcgcctt acgcaaatcc aagtctgttt gataatccaa cgcacttaaa
    23341 gagtcatcta aaatcagtaa tgctggcttg gcaatcaaag ctcttgcaat cgtcagtcgc
    23401 tgtttttgtc cgccagagaa atttttccca ttttccatga cttttgtatc taaaccattt
    23461 ggaagctgac ggacaaattc ttctgcctga gcgattttca gagcttccca acattctttt
    23521 tctgtggcgt ctttcttacc ccattgaagg ttttcacgaa tagtcccggt aaatagtaca
    23581 gaagtttggg gaacaagagc aatttgctga cggagatgat ccagctgcca agaacgaaca
    23641 tccattccgt ccattataac tgtaccggaa ctgacatcat agaaacgcgg aatcaattgt
    23701 gtcaaagtcg ttttcccgct tccggttgga ccaatgattc caaggactgt atttcgcttc
    23761 agctgaaatg taatattttg gagagaaaga ccagaatcag gagtataacg gaagtcaaca
    23821 tggtcaaaag cgataattgc ttcagaagaa aaatcgggag tagtactgac ctcagcttca
    23881 agaatcgaat tttctgtgtc tagcacctct ttcacccgat ttcctgaagc ttcggcacgt
    23941 gtgaagatca cgacgaggtt tgaaacaacg atcagtgcca aaagcatttg attcatataa
    24001 ttgatcaaag caagaacttg tccttgttgc aagctaccaa tatttacttt gatcccgcca
    24061 actgtcagca aacagatgat cccgacattc atgatcaagg ttgtagcagg tgataatagg
    24121 gcagagatat tggaaacacg taaataattg ttcgctagat catttgtgct tttatcgaac
    24181 ttctctgttt ctttttttgt ctgcgcaaat gcgcggatga cacgaacacc gctaagattc
    24241 tgactaacgt gttcattgag ctgatctagt ttttcttgca ctttttggta gagaggaacg
    24301 gtttttttga tgataaaaaa taaaatgatt gagaaaatag gcaataatgc taagaaaaac
    24361 agacctactt cccagtcgat cacaaaagcc atgaccactg acccgatact taaaaacggt
    24421 gctctgatca ataaacgaat gaccattgct aaagctagct gaagctgatt gatgtcgttt
    24481 gtcattcggg tgatcaaggt atctgttcca aaatgattca actcgttgtg agagaaagta
    24541 ttgatttttt tgattagctg attacgtaac tctgtaccaa atccttgtga agctactgaa
    24601 gcatagtatt ggcaaatgat agcacaaatc agaccaatca cagacatagc gaccatccat
    24661 aagcccattt caatgatttt tcctcggtca ttcattttta gtccattatc gatcaaggaa
    24721 gccatcatta aaggcaggac aagttcgaag acagcttcaa gaaatttgaa gaacgggccc
    24781 aaaatgattt gcttacgata gtcttttgca taacgtaata actgaatcat atgattcctc
    24841 ctattattta tttgtccaca attgaaaaaa caagtactac cacattgtag cttaggaaat
    24901 ttagaatgaa aagagaacaa gccttttcat aaatgaaagt tttattatga agaagcttta
    24961 gaaattgaat agactatttt ttttaaaaaa aagaaaatga gaaaacatgc cagtctcttc
    25021 attcatagga acgtctattt tacttaattt ttctataaat gaattctgca taaaaaatat
    25081 atcaagtaaa tgtttataga tgaaactcta tttacttctt ttttaatttg ttcttgcaat
    25141 cttttttgct acgtaatttt tgtaaaaaag tgggttgaga gaaatctaat tgattttcaa
    25201 agaaggagta tgaaaatgag aaaaatattt attcgtttat tgtgggtact atcttagagg
    25261 aataaataat agtggagaaa actatggttt ggcgcagatt ctatcaggtt tgatggaacg
    25321 aagacaacct cccgacatca agtcaaaagc tacttgagat tttgatctga aaataaaaaa
    25381 agaaaacaag gtaggaacat caatgtttct accttgtttt cgtaatcaat gggaaaaaac
    25441 taagagtggt gtacgtaatc aataaaaagg atggtgacaa cagtacctct ttactctctg
    25501 aaagcatcat aactcgtttt tcctcattat gccaataaat tgttgttata ccacatataa
    25561 ggatttgtaa tagctaaaaa cagacaggaa agttgaaatc tgtgaatctt attttgtatg
    25621 gaaggattta tagaacgcaa aaatcaagat aaagatgaat aaaaatcctg tttcggctat
    25681 atattgcgta tctacgccaa taaaacgagt ttgttctgtc atagccatat aaagcaaagg
    25741 caaaaataca actacagcga gataagatcc gatgatttct cgaaaagttt tccaggaagt
    25801 atgtttcctg tttttatatt tatccgattt cattgaatag tcatagcctc cttattcttt
    25861 catatgttga aattccagta taaaaactgg aaggaactgt acgtttttta gaataaaaat
    25921 tataagggat aagtaggctg ctgtctataa taagatatat ttttcaattc tttattaaag
    25981 attttattga caaaatgaat ccgttttcta tgatggagga ggggtgaata agttgttgaa
    26041 gaaggaaatt ttatgttact tagagaacca gacagccttt ttcgatttag aacatatgaa
    26101 cgaggtcttt acagcacaaa ggttagctga tcattttggg gtaaaaagaa acacagtcag
    26161 tcattatttg aaccagttaa atgatgagca actactagtc aaaatcaatt ctcgaccagt
    26221 gatttatttc cacaaagaag cttttgaaaa acaatttttt aagttacgca cgaattttta
    26281 tttttctatc gatgatctca aagaggaaca gccttttttc gcgcaaccaa aagacttatt
    26341 ctcttttatg atcggatacg acgccagttt gaaagaaagt atcgaacaaa tcaaaacagc
    26401 tctttactat ccagatggcg gattaccact tttgattaca ggcgaaagtg gcacaggtaa
    26461 aagttattta gttaatttgg tctatcagta ttgtctgctt catgatctgc tagaagattc
    26521 tgcaccattc atcactttta attgtgcaca atatgcagat aatcctgaac ttttgactag
    26581 caatttgttt ggacatgtta agggagcgta cactggtgca gaagaaaata aaaaaggggc
    26641 ttttgaagca gcagatggtg ggatcttgtt tttagacgag gtacatcgct taacaccaga
    26701 aggtcaggaa aaactgttca cctatcttga tcaaggtgtg atttatcgta tgggagaacc
    26761 taatttgtca cgccggatca aaacacgtct cttttttgct acgactgaag agattactag
    26821 tcatttctta acaactttca ttcgaagaat acctatccga atcgaactac ctgcacttaa
    26881 tcagcgtagt cgtaatgaac ggctagaact gatttactct ttttttctcg aagaacaaag
    26941 aaaaatgggg agccctttgt cagtcagtgg accagctttg tcacttttaa caagtcagaa
    27001 attatccgga aacataggag agctgaaaaa tatcgtcaaa gtttcagcag caaaagcata
    27061 tgctgaacag cgtgaacagc ctgaaatcca tgtcacgatc catcatttgc aaaaagaact
    27121 acttgcgcag cctattacta aaaatacagc acagcaagga atctatatta cgcaagacca
    27181 gaccttagag caattaatgg agaagcaaca gcccgaacag cagcgaatcg ttaaaagttt
    27241 tgagcaaatc ctaattgatt tcaagaaaaa taactgtctg ctatattctt gcgaaggaaa
    27301 attaaagcaa gaagtgattc aattatttga ttttttgctg tttgagacca gtagacaaga
    27361 aaaacacgag ctgctggttt attggacaca atctatccga gagacctttc gacaaatgga
    27421 aactgcctat caaatcaaat tcgatggaaa cagtgtctat gccttgagtt actatctcta
    27481 tcagcgaagc actatcaaat ggttaccgga agaacatgat attatccaac taatcaaaga
    27541 attagaacaa caagtttctc agtcttatcc atctagttat cactatgtcc aacgaattct
    27601 ggaattaagt aagatcaaat tagatattga agacacaagt atggatcgga ttttactgac
    27661 gatctatcta aaaaaagcga aatggtcaaa agaaaaacga ctgccaaaag cgatgattgc
    27721 tgctcacggt tatgcaactg ctagcagtat ggcaaatgta gtaaatcgtt tattacaaga
    27781 ggatctattt gaatcatttg atatgccact agatgtcaca ccacagcaga ttgcttcaga
    27841 aatccttgat tattgcgaaa acagcgatgt ttcaaatgga ttgatcatat tagtagacat
    27901 gggatctctg aaagaaatcc atcagttttt taaaaaacag ttatccgtac cgcttttgat
    27961 tttgaataat gtgacgacac ctttagcaat cacagtaggg gaatgcctgc aaaaaaatgt
    28021 atcattagaa gagatagcag aagagactgt tcgacagatc cagccagaat ggcgactgct
    28081 ctatccagag gaaaacaaac ccaaagcact cattactact tgcttcactg gaatcggtac
    28141 ggcggtccac ttaagtgaac tgctagaaaa aagcttacct acggcttgtc agttgaaaat
    28201 catcccatat gaatatcagc aattaaaaga taagaaaaac agtgacccat tattttccat
    28261 atacgaagtc gtaggaatga ttggcaccac agatcctgat atcaccaata tcgactatct
    28321 ttcattagaa gacctcatct cgggggaaaa gatgtctgta ctagctgaat ggttggacac
    28381 tactatgaat gcttcagaga aggaaatatt caatcagcgc atcattcgta atttttcatt
    28441 ggaaaaagta ctggattccg tgactattct agatacagag aaggtgatgg gagaaatcga
    28501 tcattttatg agagaattag aggtgcagtt gaatcgaagc atcagcaatc ccaaaaaatt
    28561 agcgttgtat gtccatgtga gctgtctcat tgaacgattg atccgacaaa tgccaatcga
    28621 aacctatcaa ggattagaga aatggaagca gtgtcaaaaa gaagggttat ctgctattaa
    28681 atctgcgttt agtgtcattg aagagcatta tagtgtcatg atccccaatt ctgagattgc
    28741 ctatatctat gatattttga gtgaagatac agagtttctc tcgatagaag aagaattttg
    28801 aacataagca agttgttgcc actaattttg gcatgcaact tgctttttta gtatgtgtaa
    28861 gtgaaaagag gagatgaaaa agtggataga gaaattatct tagcttccca tggaaaattt
    28921 gcttcaggga tattagattc attagagctg atctatggga aaaatcattc tattactgta
    28981 ttcgattgct atactgatga gaattttgat ttagcggaaa cagtaaggca gctttttatg
    29041 aggtacaaag ataaagaaat cattgttctg acggatcttt ttggcggaag tgtcaacaac
    29101 gaattcttac aatatatcaa tcgggatcat gtctatctcg ttgccggatt gaatttgcca
    29161 ctattgattg agctagtatc tcggttggac gctgaagtag agacaactgt tttgatccag
    29221 caggtgctaa ctgattcaaa aaaaatgatc cagttttgta acgagcggct caatcagaaa
    29281 atagaagaag acgaatttta ggaggaagaa aaatgattgt attgacaaga gtcgaccatc
    29341 ggttattaca cggacaagta gctttttcat ggacacaaac aataggcgca gactgtattt
    29401 tgattgctaa tgatgatgta cctacgaatg agatacgaaa gacaacgatc aaattagcca
    29461 agccacaagg agtcaaacta gtgatcaaat caattgatga ctcgattgcc gcgttgaaaa
    29521 gcggggtgac agataaatat aagttattca tcgtagtgga atcgatcgag gatgcatata
    29581 agctggcaga agcgtatcca gaaatcaaaa ccatcaactt aggagggatc aaggcaaaac
    29641 ctggtactcg cagcatcgga aaagcggtaa atattttacc agaagaggag gaacgcttga
    29701 aacgattaat tgacaaacaa atagaagtag aaatccgtca agtaccagca gataaaaaag
    29761 tggatgtaag agaagttttg taagaaagga agaacctcaa tgattgtaca agcagtctta
    29821 ttaggaattg ttgcatttgt cgcacaatca gaatatgcac tagggacatc gttgctttct
    29881 cgtccgattg tgacggggct gtttacagga atcgtgttag gtgatgtaaa aactgggatc
    29941 attatgggcg caactttaga gttagcattt atcggatcgt tctcagtagg tgcttcgatt
    30001 ccacctgatg ttgtgaccgg tgggatttta gggacggctt ttgctattac agctggagcc
    30061 ggtacagaaa ccgcgctttt actaggtttg ccgattgcta cgttgacatt gatattgaaa
    30121 aatatttact tagggctttt gattccaatt atgaaccata aagcagacaa ttatgcagaa
    30181 gaaggaaatt ataaaggagt cgagcatatg cacttgcttg ccggtatcgg tctttccttg
    30241 atgcttggtg ttgtggtaat ggtttcttat atggtgggaa gcaatacgat cggaaatcta
    30301 ttaaatatga ttcctgactt cgttcaaaag gggttgtcag tagctacagg gttgattcca
    30361 gctcttggtt ttgcgatgct tgctcgtttg ctgatcaaca aacaagttgc accatatttt
    30421 ttcttaggtt ttgctatagc ttcttactta gagattcctg tgaccggagt agctattttt
    30481 ggtgcgattt tagcagttgt ggtagtcaat attatgaatg tccgtcaact accacttcaa
    30541 acaactgcag gggaggtaga agaagatgaa gaattctgag atcaaaaaca gcaaaataac
    30601 gaaaaaagag ctaaatcacg tattttggcg ttcttttcaa atggagtttt cttggaatta
    30661 tgaacgtcag atgaatatgg cttatgttta tgcaatgatt ccgattttga aaaagttata
    30721 tcagtcgaaa gaagaaatgg cagcagcttt gaaacggcat ctagagtttt ttaacacgac
    30781 cccacatatc gttacactga ttttaggaat cacggctgca atggaggaag aaaataagga
    30841 tgatcctgaa tttgatgtga ctgcgatcga tagtatcaaa acatctttga tgggacctct
    30901 tgcagggtta ggagattctt tcttttgggg aactttgcga ttgattgcca caggtgtggg
    30961 tacctcttta gccatgcaag gaaatatttt aggccctatc ttgttcattt tgattttcaa
    31021 tattccgcac attctgtttc gctatctagc aacaggttgg ggatatcgct taggaacggg
    31081 ttttttgaaa aagatccagg caaacggtat gatggaaagt ttgacattag gcgcgtctat
    31141 tattggactg atggtcgttg gagcaatgac tgccacgatg atcaccatca atattccttt
    31201 aaaaatcggt tcaggagaaa atgctgtgac tgttcaaagt atttttgatg atatcgttcc
    31261 aaatatctta tgtcttggag catttggcat agtgttttat ctattgaaga aagaagtgaa
    31321 accattaacg atcttgatcg gactagcttt ctttggaatt tttggttcgt ggatagggat
    31381 tttttaaaaa aggagcagag aaaatgttta cgatgcaaga ttatatctat gaagaaaagg
    31441 aagtactaag tacgatcttg aaaaagaatg atttttcgac aagagaacat atgaaaaaaa
    31501 cagtgaattt actgatctta gcaacgggtt catcttataa cgcttgttta gcagcgaagc
    31561 cagcattgga atcttatggt gatcttactg tcgatattca agaacctttt tattttttca
    31621 attatggaaa actttctcct tcaatcgata ctgtgattgc tgtgtcacaa agcgggaaaa
    31681 gtgcttctac tgttgaagca gtaaaaatga tacaaaaaca agggttacct gttgttgcta
    31741 tcacaaatga cgtgcaaagt ccacttgctt tagaagctgc acaaattatt gatttaggtg
    31801 ccggggtaga atcagtaggc ttcgttacaa aaggctattc tgcgactgtt ttacagttac
    31861 tactcttagg gataggaatt ggaataagta aaaataaaat cagcaaaaaa atagaacaag
    31921 actacataca acagttgcgc aaaataatca accatttacc agcgattatt caaaaaacgg
    31981 aagaattttt tgatggatat caaagtttat ttcgtttagc acagcgtttc gtcaccattg
    32041 gatatggtcc aaactgggga acagctaaag aagcagagac gaaattgact gaaacaatcc
    32101 gcgttccgtc acaaggattt gagttagaag cttatatgca cggcccatac ctggaggcag
    32161 atgcttcgca tttgctattc tttattgaag gggaaagtgt aaataaggaa cgttcgcaaa
    32221 agttgcaaag atatatgagt cggtacgttg gagagactct caccattacc acaaaaaaag
    32281 caagaaacga gaaaacactt ggattagcaa tagaatgtga tgaatatctg tctgtattag
    32341 cgcttgtcgt tccgtttcaa ctattcgctt ataaaaccgc agtagctaaa ggtattgact
    32401 tgaacaaaaa gatttttgaa gactttgata cagtcttgaa aagtaaatta taagaggtgg
    32461 aaatcatgct gaaattcaat gaagaagaac aaatcaaagc aataaaaggc gcactagctt
    32521 tacgtccgca agtagaagaa atcatcgata aactttatgc ggaaaaattt gacgctgtct
    32581 attatctagg aatcggtgga acgtatgctt cctcgatgca agctgtcact tatatgaatg
    32641 ggaaaagcaa cttgcctgtc tttgtacagc atgctgcaga atattacact actggaaaca
    32701 aaagattaac aaaagattct atcgttattt tgtcctctgt taccggtaca actcaagaag
    32761 tagtgaaagc agtagaacaa atcaagaaag taggagcgac actgattgga tttatcgata
    32821 aagcgaacag taagttgtct cagctatgcg attttgtggt cacttatcca gctcctggaa
    32881 cagaacaaat caaatttttt atggcagcag atcgattgat gtatttgaat ggagaattcg
    32941 aagcttattc agaatactat gaacagctcg aacgttattt accaacaggg ttagtggaag
    33001 cagagaaaaa agcagatgca tttggcttat catttgcaga aaaacatcga cgtgatagta
    33061 tgcattattt tattggagca gggaatcaat ggggagctgt ttattcatat gccatgtgtt
    33121 actgggaaga acaaagctgg cttccatcga aatctatcca tgctgccgag tttcttcacg
    33181 ggacgttaga gatcgtagaa gaaacaaccc cagtcacatt atttttaggc gaagatgaac
    33241 agagagtgtt atctgaacgt gtggctaaac ttttgccaaa aatttgcagc aattatacat
    33301 tgatagacac aaaagactat ccagtagaag gtatcagtga aaaatatcgc ggacgtgttt
    33361 tgtctttctt attgatgcat gtagtgacac aacgcatcga tgctcatgtg gagcagttga
    33421 actgccatcc attagagata cgccgctact atcgtcagtt tgattattag gatagactgg
    33481 ataaaaagaa tataaaaaat aaagagagca gcgataactg ctccctttat ttttttaaaa
    33541 tattggcatc aattacgtta taaaacacat tttttgcatt atctacagtt caacttataa
    33601 tctgtttaat gggacatgtg ggtgccaacc attttttgtt atgcaatagt actatttagt
    33661 tgttgcatgg atccgtagta aaagtccaag tacaacgagt tgcgccagtt tacatagcgt
    33721 tttgtatcca gaatgttgac taaaacaaaa gttcctatgt caaccgtcaa cagagacaat
    33781 ctgtccgttg caggacctga cagatttaga aatgttcaat ctgtctctta tgtattttaa
    33841 atcaatactc actaggagaa gtttcctaac ctcctaatag taatgctggt agtaacattg
    33901 tcaaaactgc ttcctcttag gaacaagcaa agcataacga gtgtaaaaat aaaatgtaga
    33961 ctattgtaac atatcattga ttatttcaag taaaaacgat aaaagaagta aacaaacact
    34021 taaaaacaat ggaaattagt cccaacttta agaaatgtat actataatgg aaattatcaa
    34081 ttatttattt ggaggaatat ccatgaaaca aaaaatcgca gttcttggtc ctggatcttg
    34141 gggcactgct ttagcacaaa cattggcaga aaacgggcat gatgtccgta tttggggaaa
    34201 tgtacctgaa cagattgatg aaatcaataa gtatcataca aatcagcatt ttttacctga
    34261 tttgacgatc ccagaatcga ttatcggata taaagaattg gcagaagcag tggataacgc
    34321 agatgctatt ttatttgttg ttccaacaaa agcgattcgt tcagtcgcac aggaacttat
    34381 tggtaaaatg aatactaagc caatcattat acatgcaagt aaaggactag aacaagatac
    34441 gcataaacga atctcagaag ttttggctga agaaattcca gaagaaaaaa gacaggcaat
    34501 tgttgtatta tctggtccta gccatgctga ggaagtggca gtacatgata tcacaacaat
    34561 tacagctgca agtattgatc aaaaagcagc agcctatgta caaaaactgt tcatgaatga
    34621 ttatttcagg atttatacaa ataatgatgt gattggcgta gaaactggtg cagcactgaa
    34681 aaatatcatt gcaattggtg ccggcgctat ccatggatta ggattcggag atgatgcaaa
    34741 agcagcaatc atgactcgag gattggcaga aatcagccgt cttggtgtcg cgatgggtgc
    34801 caatcctctg acatttatcg gtttgagtgg tgtgggggac ttgatcgtta cttgtacaag
    34861 tgttcattct cgcaattggc gtgccggtaa cttgttagga cagggacata agctggaaga
    34921 agttctagaa aacatgggaa tggtcgttga gggtgtggca acgacaaaag cagcagtaga
    34981 gctagctcaa cagctaggtg ttgagatgcc aattactcaa acaatctata atgttttgta
    35041 taatggagaa gatatcaaaa aagcagcaaa agaaatcatg ttacgtgacg gaaaaatgga
    35101 gaatgaattt tctcttcgtt aaatagatga tcaatagtta atcgtcgttt aggaggaaca
    35161 gcaagtgaag gtcaaaaaag cagtcattcc tgccgctggg ctaggaacac gttttttgcc
    35221 ggcaacaaaa gccatggcaa aagaaatgct tccaatcgtg gataaaccaa cgatccagtt
    35281 tattgtggaa gaagcattgg attcgggaat cgaagacatc ttgatcgtaa cgggaaaaga
    35341 aaaaagaccc attgaagatc actttgatgc aaatatcgaa ttggaaaaca atttgcggga
    35401 aaaggaaaaa acagaattac tcgctttagt tgaagaaacg actcaagtca atcttcactt
    35461 catccgtcaa tctcatccaa gaggactggg ggatgccgtg cttcaagcaa aagcatttat
    35521 aggaaatgaa ccgtttgtcg tcatgctggg ggatgatttg atgaaagatg atatcccatt
    35581 gactcaacaa ttgatgatgg attatgaaga aacacaagct tccgctgttg ccgtcatgcg
    35641 tgtaccagaa aatgaaacat ctaaatacgg aattattgat cctaaaacag atagcgaaaa
    35701 gggtcgttgc agagtaaaag ggtttgtaga aaaacctgaa atgggaaaag caccaagtaa
    35761 tttagccatt atcggacgtt atctactgac tcctaaaata tttgagatat tagaaactca
    35821 agaaccagga gcaggaaacg agatacagct aacggatgca cttcagactc ttaaccagac
    35881 agaggcggtc tatgcgagag agtttaaagg aaaaagatac gacgtaggcg ataagttagg
    35941 atatatgaag acaaatattg aatatggact tcaacattcg gaaattggga cttcattaag
    36001 tgcatatatt atccagttga gtaaaaagct aagaacagaa agttaactgg aaataagtgg
    36061 cctgctgaga atgaaaggct atttgttatt aaagcggcag cttgtgcgtc atttgcgcaa
    36121 ctgtcgtttt agttttttga ctctagatca gttgagtcgt ggaaaacgaa agatagaaaa
    36181 agactttcgt gaatagattc agaaaatatt atgctaatgg tttaattttt ttttaagttg
    36241 tataaaagaa aatgattaca taagagaaat gaaagccaag ccagaagatt catagtagaa
    36301 taaaaaggcg aattttttaa ttataaaaaa aggtgtgtgt tcactatggg aaaattagtc
    36361 gctgttgcac agtcgctgct tgatatactc aagtggctga tggaaggaag caattggata
    36421 tttgtgttgc cactattgct tattagtcta tttatcatgt ttcgcatggt cagaaaaaaa
    36481 gaaacgtttc tgatttttat ctggtatgca gcatccgttg gggttgctac cttgatggtt
    36541 gaattggcgt taggtagttg ggaagcttgc gtatttgctt tattttttgc tgtactgtat
    36601 ctaatcattt atatcccata tatgaaaaga aagtctcgga taggcagaaa aggtagacat
    36661 acaactactt tttctagtac agattctctc gaacaaagta gaagaacgag aagaagacgg
    36721 taatatttag taggtatacg caaaaaaaga taaaataatg gataaactat tgagatgaga
    36781 gatttattta attggtggaa aaaagctttt ttcacttata taaaagaatc ttttttaaag
    36841 gaatgcttgt tgtatcggga taagccattc ctttttttat gttatttata tatatataaa
    36901 tcataccaat gttt
//
LOCUS       DACBZK010000019        36069 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.019, whole genome shotgun sequence.
ACCESSION   DACBZK010000019 DACBZK010000000
VERSION     DACBZK010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.019"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..719
                     /locus_tag="IVD66_001044"
     CDS             <1..719
                     /locus_tag="IVD66_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145282.1"
                     /translation="KLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGYPETANYI
                     NINFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANNQNKLNFRVE
                     FDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVREELRLNKF
                     PDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMYLQHPQYL
                     NFGVEIATPLEEWKMEQGLD"
     gene            complement(736..1152)
                     /locus_tag="IVD66_001045"
     CDS             complement(736..1152)
                     /locus_tag="IVD66_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145283.1"
                     /translation="MNKKRKLSVLITLISILTILSGILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETGTTTKKDKSAEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            1545..2792
                     /locus_tag="IVD66_001046"
     CDS             1545..2792
                     /locus_tag="IVD66_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145284.1"
                     /translation="MNMKKNSLGMVLFASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPVENTEQENKKSETTKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTEADTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKSMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            3062..5452
                     /locus_tag="IVD66_001047"
     CDS             3062..5452
                     /locus_tag="IVD66_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HAP6145285.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMVLSTLIMPFSAIRAEADVTKPT
                     SAKFTETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     EFSYTATNTIKKGKIKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGAFKQEGITVKDDGQTFEYTATNTLKKGVVKVHKVDQDGKPL
                     ENAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPTGYTGAFKQEGITVK
                     DDGQTFEYTATNTLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDSNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQIFEYTVINHRVPETVRTGGIGTSAFLLVFLVAGLGMGLLYYREQRKVK"
     gene            5501..7336
                     /locus_tag="IVD66_001048"
     CDS             5501..7336
                     /locus_tag="IVD66_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP6145286.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSFGLGEQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGKPVSDIDNKGKEIALPNGVQPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPVQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANKTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     DYEKYVVKDVLGEELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTDSGMDKLQKKFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNRVTYLKQDPTTKAITWVEDKSKATEFVSGTDGKFQ
                     VEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSK
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            7405..8268
                     /locus_tag="IVD66_001049"
     CDS             7405..8268
                     /locus_tag="IVD66_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP6145287.1"
                     /translation="MSMKKKNIKLIILRIGMLLCLGVGLYPVITQAYTYYQTQQTLNA
                     YKEKYDEASEKENEEIFKKYSEINRKRKETEQTLVTIPEDNNNIPSNGNLQKDKLGEL
                     VGEILIPKINVDLPIYNGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKY
                     FTDLELLKLGDKFFINVAGKKLAYKVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVG
                     ENSHRLLVRGVRIPYKKNIVEKEKKKEDLKVKAQINWYPIIVVGVLSIIALIVIIKKI
                     VAKRRGMKNEE"
     gene            8258..9337
                     /locus_tag="IVD66_001050"
     CDS             8258..9337
                     /locus_tag="IVD66_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP6145288.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIDK
                     KQTPSKEEVAKNVGQILSNNENQKVNETQESDNESFDMDEAEGKVNPYTGDVFSKNQT
                     KDFEPSTYSGAVGYIYIPKINVLELLFLGASQEHLYRGVAQMSATSLPLSGKGHQTVI
                     AGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRSDVIKNYGQNSTLTDIPDL
                     DMLTLYTCHPFPQNYDRLLVRSLRDDKAKYITPQVTVGNTAYADAIDSESVSAKPETV
                     TSSNDLFEDVDRANKELDGNNDLNIPEQTSVEMQDRTFAEKASSIFTGITNKHQKMLL
                     VIWTVLGALASLKVLLLLIKEFRKA"
     gene            9676..10476
                     /locus_tag="IVD66_001051"
     CDS             9676..10476
                     /locus_tag="IVD66_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145289.1"
                     /translation="MVVISKTALDSLAKVFSSRFDGAEFVEYLSQNESGKTLIETLKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLMGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYADDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            10564..11370
                     /locus_tag="IVD66_001052"
     CDS             10564..11370
                     /locus_tag="IVD66_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145290.1"
                     /translation="MRGDQTMSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWIS
                     AVGEENIEFEIKNMDDLKAKFPFIASKLSQFAEEKSWNELVSFSEKIYDITQEDECVS
                     WEMNNQYKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYA
                     EYLKTERDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALS
                     QYSSDEEVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            11602..12471
                     /locus_tag="IVD66_001053"
     CDS             11602..12471
                     /locus_tag="IVD66_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAP6145291.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAVNSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVKAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            12491..12838
                     /locus_tag="IVD66_001054"
     CDS             12491..12838
                     /locus_tag="IVD66_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145292.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            12851..14113
                     /locus_tag="IVD66_001055"
     CDS             12851..14113
                     /locus_tag="IVD66_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145293.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            14193..15569
                     /locus_tag="IVD66_001056"
     CDS             14193..15569
                     /locus_tag="IVD66_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAP6145294.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTAMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMIIKLVNGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAESRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANSSSKEPSIEKKSTFALKLEKNKEEKEKQGAKTLEKLQAEKLEKVLKALDK
                     ADSEPQTSNNTNNEQPISSKTKPKTTDPKVSVNVTITTDKSEKKQVNGTTSPIMQKML
                     KAKKQVHK"
     gene            15566..16195
                     /locus_tag="IVD66_001057"
     CDS             15566..16195
                     /locus_tag="IVD66_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145295.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRTKKRDKKAVLTPKQMLDHGI
                     LGVKVLEVNKPFESNSAREKLLGAEADVAYFYHDKSKHQISIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRVQINKFEKKVRK
                     FNDRKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            16214..16693
                     /locus_tag="IVD66_001058"
     CDS             16214..16693
                     /locus_tag="IVD66_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145296.1"
                     /translation="MLELLEANRTGFNQKLEVGETIEYKDKNYIIIGIYNTRINRIGD
                     PRITSDLVCQSVNYSPDLTSRYKKYVLLEYRHKITDEIGVNNTRNIFKIGTVIPYSNN
                     EEKIFYQIYGIEKFEYEHVDLLVTYQMRLIEPWSQVEIDKAVKLNRLSKFNVLGNAF"
     gene            17195..17248
                     /locus_tag="IVD66_001059"
                     /pseudo
     CDS             17195..17248
                     /locus_tag="IVD66_001059"
                     /inference="COORDINATES: protein motif:HMM:NF019230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17252..17851
                     /locus_tag="IVD66_001060"
     CDS             17252..17851
                     /locus_tag="IVD66_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAP6145297.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGESIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLHSNIVSMGLSGGIFGWIALFAIAYIRFDSKKHLLLSVFVLLIIGIL
                     LVSTFESGETNVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            17867..18343
                     /locus_tag="IVD66_001061"
     CDS             17867..18343
                     /locus_tag="IVD66_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145298.1"
                     /translation="MPKKKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRIFEWLNTNTEQEPLRAISNL
                     FEFGMKHWFNAVEKDADLQEAFDTLSEDSKSMRDLLITYLNEHEFEQTKVKKKNKK"
     gene            18360..19262
                     /locus_tag="IVD66_001062"
     CDS             18360..19262
                     /locus_tag="IVD66_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145299.1"
                     /translation="MLFTLLGYLCLVLAFFGAIAIFVGQFQANNPIMRNIGIGIVIIS
                     LIVFGATKIFGSNDQQFGISGVDNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDDK
                     KASDDVLATIKPSQSQFEVFYTVKENNPVRKLTLVFNVDGEEYYKDVKINKASTKKIV
                     ESAKKEVATEESTTESSSTVEVELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQRINVTLFNSVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGADLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            19335..19526
                     /locus_tag="IVD66_001063"
     CDS             19335..19526
                     /locus_tag="IVD66_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145300.1"
                     /translation="MVVNKEKVRKYVTLKIASVKYLEKRAKEEERARGKKVTVSELLE
                     ELIENDQTIRRAFTNRSIR"
     gene            19690..20277
                     /locus_tag="IVD66_001064"
     CDS             19690..20277
                     /locus_tag="IVD66_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145301.1"
                     /translation="MENNNDIRHFSIGERVTTVSELSKDYRDKEGTIISLNKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNDGSHSIEKAILVYPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITNKEAKVEDVLTVRELQSLIEYRNKQITNPEYLKKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDNFKKIYLKEIEKD"
     gene            20277..21176
                     /locus_tag="IVD66_001065"
     CDS             20277..21176
                     /locus_tag="IVD66_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HAP6145302.1"
                     /translation="MWSVTLPFQPVSAPRPSARRNVSDATNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQGLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            21176..22090
                     /locus_tag="IVD66_001066"
     CDS             21176..22090
                     /locus_tag="IVD66_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145303.1"
                     /translation="MNNNEKILHVLDSFETIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKKAMELNEDRRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPSNSGIGIVLKAIDEEEIEAFIPPEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCESYEVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     EARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNATNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKKAE"
     gene            22142..22357
                     /locus_tag="IVD66_001067"
     CDS             22142..22357
                     /locus_tag="IVD66_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145304.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NPVVLKQFWLNNFSYKDFIKEKANTLY"
     gene            22548..22802
                     /locus_tag="IVD66_001068"
     CDS             22548..22802
                     /locus_tag="IVD66_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3034 family protein"
                     /protein_id="HAP6145305.1"
                     /translation="MKKEELIDIFQIVERANNMGIMFFDRISLKMDLSVAHQEFNLRL
                     KALLNSDDVNFAHDVVGIQNHIDRENKRMGDGFLPRYSSL"
     gene            22980..24023
                     /locus_tag="IVD66_001069"
     CDS             22980..24023
                     /locus_tag="IVD66_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyhydrolase"
                     /protein_id="HAP6145306.1"
                     /translation="MKKILVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGTPVYRLYNRYNGEHFYTIDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNIISRQGWKIEGTGWYAMPNS
                     APNPAPAPSNEKVLNVPVIWQGNTMLCEGASLLEGLHYKGVATNQNLTSFVNYMPRAN
                     DNNPYHGYSGEWRYNVNGTYQGMMPDPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGN
                     PVVTWITYNYATPEFKQMPWGRAVWNGHVVLVDGFKNGAYHVVDPVFGAKWINAGTYE
                     KSFNVTGMAVAVR"
     gene            24199..24429
                     /locus_tag="IVD66_001070"
     CDS             24199..24429
                     /locus_tag="IVD66_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145307.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEEEYKENIPENLQGS
                     ERYEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            24432..24689
                     /locus_tag="IVD66_001071"
     CDS             24432..24689
                     /locus_tag="IVD66_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145308.1"
                     /translation="MTNEDFRSEQKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEEIMKREGFQTDNDSKKVE"
     gene            24804..25775
                     /locus_tag="IVD66_001072"
     CDS             24804..25775
                     /locus_tag="IVD66_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145309.1"
                     /translation="MKTKGFNVKENAIGGNKIFKKDIYVWFNGKKYMTTNKRWSELVQ
                     NTVKKVMPDGYHFNYIQCSQTTESIYFSILNENRLYYFRVSSHHRKKREDNVTTFLSG
                     KYNGFKELSEAIGEYLKSNRFVRISDKHILILLLYLNNSFKLFWRDDTFYYIENGMDI
                     YSGINGTLKHYIKALLRYGVLYQEDLSNQIKISNSGKSLLAKYKKLLSPIYKGIDMEA
                     VNSETLFNLVVDEKFANEFFKSKKIESLNNLFPENAIKAYVDNNKSRLYNWFIPKRLR
                     GKIKIGDQVKVINLNHTKIVTVTELYIAEKEEITKMKPVIKILDNKE"
     gene            25785..26579
                     /locus_tag="IVD66_001073"
     CDS             25785..26579
                     /locus_tag="IVD66_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145310.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSRRLRITVEYGTNESATELKQRYLDTRREASKKYDDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLGLAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMDKYRV"
     gene            26608..27726
                     /locus_tag="IVD66_001074"
     CDS             26608..27726
                     /locus_tag="IVD66_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145311.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKKTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLKTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETNTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGNSKDEVKGVVIDDDFEFDFD"
     gene            27759..28079
                     /locus_tag="IVD66_001075"
     CDS             27759..28079
                     /locus_tag="IVD66_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145312.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            28334..29227
                     /locus_tag="IVD66_001076"
     CDS             28334..29227
                     /locus_tag="IVD66_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145313.1"
                     /translation="MRTHYIYLEDKIVDEIPAKSREQARKLFIEKYKEINGDSEVQKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIGTVIDELISGKYDYAFDF
                     ENEKDYRSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHEELSEGTEKYTIADMVNEVETLLASFFENGHVNDEWRKEEPKRVNAYI
                     ARLKRFIDKYKENSDKFSKDK"
     gene            29247..30881
                     /locus_tag="IVD66_001077"
     CDS             29247..30881
                     /locus_tag="IVD66_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145314.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNNGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYLNHGLYYR
                     VMSEISNKDKIFYLDNHVNMSLTIKRIYDLLYVYKH"
     gene            30853..32079
                     /locus_tag="IVD66_001078"
     CDS             30853..32079
                     /locus_tag="IVD66_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145315.1"
                     /translation="MIFYMFININEVLKLTTITMTKKIEVYVDGSQEERDSFFDFFWK
                     NSREYVKALNLVYKQLMFEELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKL
                     DKAKAELSKLRNEKNKEAREILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASK
                     DFGNDFIGIVTGQRTPRIYKNRSKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLG
                     SKPRKARDVASVLQHIMDGDYKLNQSNLIFDGRKLFFNLTISFEKRYNELEFKEGNEL
                     IVNFADLCSGECLVNNKSVMSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRK
                     LDQDRWEAIKKRESNFVKTYNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLK
                     EQLVNKGKRYGIEVRS"
     gene            32530..33855
                     /locus_tag="IVD66_001079"
     CDS             32530..33855
                     /locus_tag="IVD66_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAP6145316.1"
                     /translation="MFDYSREPVNDYFLIDMKSFYASVECIERNLDPMTTPLIVMSRS
                     DNTGSGLTLASSPTAKKKYHITNVSRATDLPYPLPKELHIVPPRMNLYIKKNMEVNQI
                     FRKYVADEDLLIYSIDESILKVTKSLNLFTSSGTRSERRRELAKIIKDEIQKETGLIA
                     TVGIGDNPLLAKLALDNEAKSSKEFIAEWSYETVPEKIWKINEMTDFWGIGSRMKKRL
                     NHMGIMSIEDLANWNPYTIKSQLGVIGLQLYFHTNGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPKDYTRREEVELVVKEMAEQVAIRIRQHNCKTGCVRLAIGTSILEEKSGFSHQMKI
                     PITDNTKELQNYCLFLFNKFYEGQEVRHIGVTYSRLVYTDSLQLDLFSDPRKKIAEEN
                     LDRIIDKIRQKYGFTAIIHASSMLEGARSITRSTLIGGHAGGLGGLHND"
     gene            33848..34195
                     /locus_tag="IVD66_001080"
     CDS             33848..34195
                     /locus_tag="IVD66_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145317.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFAELLKWSQI"
     gene            34546..35367
                     /locus_tag="IVD66_001081"
     CDS             34546..35367
                     /locus_tag="IVD66_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAP6145318.1"
                     /translation="MGLLVPRANTYTIPLTKRQLIAKRYQRITRAINREFWNSESDTA
                     HSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQVIKNAFQEILPN
                     SDIRADGQVVKINFHDGIKFEIVPAFNEKDYWGESKGFIYPDSNMGGNWKATNPKKEQ
                     EAMKLKNTKSNNLLYATCKHFRHVRDTEFTSYHLSGIVIDSFVYEAMGNWKFVENNSG
                     GQNISSVSYETALLEYYNSHKVMGGLNLYSPGSNQFVNSDSSIICLEKVLKKIAL"
     gene            35387..35947
                     /locus_tag="IVD66_001082"
     CDS             35387..35947
                     /locus_tag="IVD66_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HAP6145319.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNETHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
BASE COUNT        13764 a         4889 c         7234 g        10182 t
ORIGIN      
        1 aaaagttatt agaagaaacg tggaatccaa aagaatttag tgaatttttt atggagaatt
       61 ttgaaactga cttagcagtg attgttaaag atgctcttag agagcaaggg tatcctgaaa
      121 ctgcaaacta tataaacatt aattttactt tgtatactga aaataaagga acttgggatt
      181 tttgggctac tttagcaaat aaggagttaa gtgataaatc agacacagga attcgtaact
      241 tttttgaatc aaacagagat gattatatgt atgctaacaa tcaaaataaa ttgaacttta
      301 gagtagagtt tgatgaaaca cctgaagaat ttatagaaag acaaccgcct aaagaaaatg
      361 tagcaaaggt attggaagat cgttggaatt cagatgaaat agtttcaaca attagcgaac
      421 taggcggaca atatgaaccg ctagtagaag cggttagaga agagctaaga ctgaataagt
      481 ttcctgatgt tcaaaatatt gatgtttctc aaattgaaat aaacgtcaag atcacgaata
      541 aacttgatta tggtagttgg gcagatatag cattagaaaa atacatctac tcaacgttaa
      601 aagagtttat cgaaaataga atggatatca tgtatctaca gcatccacag tatttaaact
      661 ttggtgttga aatagctaca cctcttgaag aatggaaaat ggagcaaggg cttgactagc
      721 ctttgctcca tttttttatt ttacaaatga atacagttcg tcgtttttac caagaatgat
      781 tgtttgccca actttgagat tgtcaggtga tccttcagcg gtttgtaagg agaacgttcc
      841 attgaactta tcggataccg ttataggtag ctttaattct gatccttcct catctttgag
      901 aattgctgtt tttcgttcat caaaataaac agtctttatt aaataatttt tcgtagtgat
      961 ctcagcagat ttgtcttttt ttgtagtagt accagtttct ttagaattag aggtattttc
     1021 tacgactatt ccatctttgg catttgagct tgtgtttatt tgattgaata ttttcagcga
     1081 caagataccg ctaagaatag tcaatataga aataagtgta attaatactg ataatttcct
     1141 ttttttgttc attttttctt aacttccttt tttgttttga ttagttagat attccttatc
     1201 taacaagcat ttttaggcta ttaaatgaag atgaacccca aaaaaatatt gcaattatga
     1261 cagtgcaatg gtactattat tatacaataa attttgcgaa aggggtaggt ctaaatcgca
     1321 aacaaaaaga aattgaacct agacaaatac aacttgtata ccgcaaggga agcaagtttg
     1381 attttgggta aaggtagaaa ttatgttaca aacataatta actattatcc aaatcgtttg
     1441 cctaaaggtt cgttcaagaa agtgggtgac aaaacctata ttataacgga agaaggaata
     1501 gaagcattgc gatcacaaac agaaaataaa aacaaaaaga aggaatgaat atgaagaaaa
     1561 attcgcttgg tatggtttta tttgcatcag ctgtacttgc ggggttatca gtaccagtaa
     1621 cctcacatgc tgatgaatgg actgcaaaca caccggatca aatccaaatt acaacaggac
     1681 aatcaagtta tgcgttcaaa aaaggagata ctatttggtc aactgtagag aagcttaaaa
     1741 gcttaggtta caagactact gttgctgagt ttgccgaatt gaacaatgtt gatttggcaa
     1801 aaggagaaca acggactatc ccaattggac gaactttcaa catcagtaaa gatacattaa
     1861 cagttaagga agcagatggc gaagtagtta gtcaaactgt tcaaaaggat aaacctgatc
     1921 ctgttgaaaa tacggagcaa gagaacaaaa aatccgagac tacaaaagaa tcggaaccaa
     1981 cagcaaacac ttctgataag acagaaacaa gtgcttcaag tgttgatgga gcaagttcat
     2041 ctaatacaaa taattctaca agtgagaaag aagcatcaca gggaacaagt gaaagtagca
     2101 ctacggaagc tgatactgga acatcaacaa ataactcaca atcaacatca aatgatgcaa
     2161 atgaatcaac cagtacatct tctagtgatc aatcacaaac aggttcgagt gatgaaactg
     2221 acagttctac ttcaccaagt aaacccgaac aaccaactaa tgttgtgcta ggcgttccat
     2281 ttattagtca aggtaacaca atgctttgcg aaggaacatc tttgctagaa gcgttacatt
     2341 ataaaggtgt tgcaacaaat caagatttaa tgacttttgt taaatcaatg ccactatctc
     2401 ctgataataa tccaaataat ggtttttctg gtgaatggag acacaatgtg gatggaactt
     2461 atcaaggtat gaatccggct cctgtagttt catggggtgt tgctaatggc ggaaatgttg
     2521 tagatatttc tggttcatcg gtacaaggat taaaagatga gattgtaaat ggaaatcctg
     2581 tagtagcatg ggtaacttat gcctttgaac ctgctcaaca taaatcaatg ttttggggcg
     2641 atgctatttg gaatcgacat gtagtagccg ttgatggatt taaagacggt ttttaccatg
     2701 ttgtcgatcc tgtgtttggg gcaagttgga ttaatgcagg atcatttgaa acagcatata
     2761 acgtatctca attagcggtt tcggtacgtt aataaaagag atcgtttata tactaagtag
     2821 ttaagtatag tctttatttg cccttactta actacttaga aaacttgttg ctcatggtgg
     2881 gtagaactaa aaggggtgat gctatgaata atagagcgtt gaaacatctt gctttcaacg
     2941 aaaaaagtga ttaataggtg tggtgatttt aacttaggaa tgggcgcgaa ggtcattacc
     3001 acaccgacat atcgtggctc attttcttcg cctaactggt ataaagaagg agtaacgaga
     3061 gatgaagcat gaaaaaacga taattttaaa atcaaaaata atttattgtt ttgcgacttt
     3121 agtaatggtg ttatctacgc ttataatgcc tttttcagca ataagagctg aagcagatgt
     3181 cacaaaaccg acaagtgcaa aatttacaga aactggcgta aaaacagacg gttatattag
     3241 ggttaatatg ccgaatcatc caaatgaatg gatgatttca agtcaattta aagattctca
     3301 tggaaatatt ggatattgta tggattcaga attgccatcc ccaacaggaa gtggagccgg
     3361 aagcttgaag tacaagggag ctggcagtga tgagttctat cgtatgttta aaggtggttt
     3421 tccatcaaaa acagcaaagg aactgggtgc aggaaatgat acagaagcat ggtatgcaac
     3481 acaattagtt tcatgggttt tagccggaaa ctttaaagtt tcacagattg tatggtcaca
     3541 tccaaaccat accgccgcag aaacagctcg tgtaaaaaaa gcatttgaaa aaatttatga
     3601 ctatgctaag aatggaaaag atacgcccaa cactgagttt tctatcacag cttctaagac
     3661 agctgacgaa ggaaaatatc acactttcac atataaaaca gcatcaaata agactggtaa
     3721 tgcgaagctc acttttacat cagcaaaacc tgctggtatg aagatttatg atgcagatgg
     3781 taaagaaatt actaacaaca ctgtaaaatt aaattcaagt tttactatta aagtacctgt
     3841 gactacacca agtggtactt tgtcatttaa aggtactgct aatgttagca cgaccaatcc
     3901 ttttactttt gatggacgag gtgtgtatca agatgctgta gttatgatca ctacttcaga
     3961 aacaaaggac tctaaatctt tgagtgctaa atggacaaga gctgttggtc aggtaacagt
     4021 taagaaagtt gatcaagatg gaaatgcttt aaaaggagcg gagttcactc taactgacaa
     4081 taacaatgct aaatctgtta agacaaccgg agatgatggg ttagctacgt ttgatttgca
     4141 acaaggctta acatacagct tagaagaaac aaaagttcct gaaggttatc aaggttcatt
     4201 taaaaaggat ggtattactg ttaataccga tggacaagaa tttagttaca ctgctacgaa
     4261 cacaattaaa aaaggtaaaa taaaagttaa aaaggttgac caagatggaa aaccattagc
     4321 taatgctgaa tttaccttga cggatgattc atcccaaaca caagcagaaa aaacagatga
     4381 aaacggactt gcaagcttcg atattgtagc aaacaagacc tacagccttg aagagaccgg
     4441 agtaccaact ggttatacag gcgcattcaa gcaagaagga atcaccgtta aagatgatgg
     4501 acaaactttt gaatatacag ctacaaacac tttgaaaaaa ggtgtagtaa aagttcataa
     4561 agtcgatcaa gatggaaaac ctttggaaaa tgcagagttc actttaaccg atgaaaaagg
     4621 tgcaacacaa gtagaaaaaa cagatgaaaa tggacttgca agcttcaata ttgtagcaaa
     4681 caagacgtat agcctagaag aaaccggagt accaactggt tatacaggcg cattcaagca
     4741 agaaggaatt accgttaaag atgatggaca aacttttgaa tatacagcta caaacacttt
     4801 gaaaaaaggt gtagtaaaag ttcataaagt cgatcaagat ggaaaacctt tagcagatgc
     4861 agaattcacc ttaacggatg aaaaaggtgt aaaagaagtt aaaaagacgg atgcaactgg
     4921 tctggctacg ttcaacatta ttgcgaacaa aacttacaac ttagaagaaa caaaagtacc
     4981 aacaggttac acaggcgcat tcaaacaaga aggaattacc gtcaaagatg atggacaagt
     5041 ctttgaatat acagctaaaa acactttgaa aaaaggtgtg atcaaagttc ataaagtgga
     5101 tgatcaaggg aaagcattag caaacgcaga attcactttg acggacgaca aaggtgtaaa
     5161 agttgtacaa aaaacggaca gcaatggctt ggcaacattt aatattgttg caaacaaaac
     5221 gtacaaaatc gaagaaacac aaaaccctaa tggttacaca ggaaaatggt ctaaagaagg
     5281 catcactgtt gctgacgatg gacaaatttt tgaatatacg gtaattaacc atcgtgtacc
     5341 tgaaacagtc cgcacaggag gaatcggtac atcagctttt cttcttgtat ttctagttgc
     5401 aggattgggc atggggttgt tgtattatcg agaacaacgc aaagtaaaat aaaaaatcgg
     5461 taatggaaaa gaagtaaata tgaaaaaaga aggctgacgt atgaaatcga aaaaaatttt
     5521 ttcaaatcta atgctatttg gtacattgct aggagtggga ttgggcgcaa gctcaatctc
     5581 ttctagtttt ggacttgggg agcaagtagc atatgcacaa caaaactata attatcaagg
     5641 aactggaact attcatatcc ataaagtaac aaatactaat ggggatggga aacctgtctc
     5701 agatattgat aacaaaggga aagaaatagc tttaccaaat ggtgtacaac ctcttgaagg
     5761 cgttgagttc tcttatgtga aacttactaa agatgaagct aaatccttgg gatggacaga
     5821 tagtgatact acaaaaggtc aacatattga tgatgctaaa gcacgattat tactaaacaa
     5881 aaaatacagt gaagtaagta gaatgaagac tgattcacaa gggaatatag acatacctgt
     5941 acaagtaaat acagacgatt taacagataa cttgtatttg attgttgaaa caggaacagt
     6001 caaaggtgta gttgaagaag cgtatcctat gattgttaac gtacctgaac taaacggatc
     6061 agatgatcaa tactttaatt atgatgtaca tgtctatcct aaaaactatt tccaattaaa
     6121 ctcagcagaa cttgataaaa aagacgaaga tggaaaggct cttgccggaa ctgtttttga
     6181 attgcgaaaa gatgatgggt ctgatcaggt cgttggaact tataaaacag atagcactgg
     6241 taaattaact gtagacggtt tggaattagg tgactattat ttcctagaaa cagatttggg
     6301 aacggatgct aataaaacaa cctatttact agatggaaaa aaattcaaat ttagcgttaa
     6361 acgtggggag actgctaaag tagttcttga tgttaccaac tataaacgtc ctgtaattac
     6421 taaggtgatt gataaagaaa ctgttgatac tggtgaagat gttcagtata cattgaaacc
     6481 atctattcct ggtaatattg gagattacga aaaatacgtt gtcaaagatg tactaggaga
     6541 agagttgact tatgattctt cagaagtgat agaaggaatg actttagata ctgactacag
     6601 catcgagcgt gacggacaaa cgacaaacta tgtctttact gattctggta tggataaact
     6661 tcagaaaaaa tttgatgcag gggatcgctt ctttacaatc ttgatgaatg ctcacacgaa
     6721 tagtaaagct aaaatggata caccacttaa aaatgacgtt tcaacaatct acaacaatgg
     6781 atatgagcct gaagacgaaa cgccagttga tcatgcttat acaatcattg gtgaccacca
     6841 attcattaaa acagatgggg atacaagcaa agcgttgagt ggagcgaaat tcgtagtgaa
     6901 gaacaaaatt gatcctaaca gagttactta cctgaaacaa gacccaacaa cgaaagctat
     6961 tacttgggtt gaagataaat cgaaagctac tgaattcgta tctggtacag acggtaagtt
     7021 ccaagttgaa ggtttgcaat atacctatga tgtagatttt gataaacaag gtaatccaac
     7081 aattacagat aaaaaaatca atgattatgc tcttgaagaa gttgttgctc cttctggata
     7141 tacaccaaca cgaaatgatg ttccatttgt agtatctaat gatgatgctt caagtaaagt
     7201 gacagacata aaaaacctga aaactcctga aacagttcgt acaggaggaa ttggaacagt
     7261 agtattccta gtggttgcag gtgtcgcagg aacagggttg tatgttgttt acaaacggga
     7321 acaacataaa gcttaattat taaaaatccc ctagagtgtt tttggctcta gggtttcttt
     7381 ttaaaaagag tgtgaaaagt aggtatgagt atgaaaaaaa agaatatcaa gctaatcatc
     7441 ttaagaattg ggatgttgct atgtctagga gtaggtctat accctgtaat tactcaggct
     7501 tatacctatt accagactca acaaacgtta aatgcctata aggaaaaata tgatgaagct
     7561 tctgaaaagg agaatgaaga aatcttcaaa aaatattcgg aaatcaatag gaaacgaaaa
     7621 gaaacagaac aaaccttagt tacgattcct gaagataata acaatattcc gtcaaatgga
     7681 aatcttcaaa aggataaatt gggtgaatta gtaggtgaga ttcttatacc aaaaataaat
     7741 gtggatttac cgatttataa tggcgtaaac gattttcaat tatcagcagg agcaggaata
     7801 cttactggaa ctgattatcc gaccggtggg attggaaacc attctgtcat atcagctcat
     7861 tcaggtattc ctaataaaaa atattttaca gatttagaat tgctcaaact tggtgataaa
     7921 ttctttatca atgttgcagg aaaaaaactt gcttataaag tagatcggat aaaaacaatt
     7981 ctacctaccg aatttgagga tttgcttcct gtagcaggga aagattatgt aacgcttatg
     8041 acgtgtactc ctgttggaga aaattctcat aggttacttg ttagaggagt tagaataccc
     8101 tacaaaaaaa atattgttga gaaagaaaaa aagaaagaag acttaaaagt aaaggcgcag
     8161 ataaactggt atcccatcat agttgtaggt gttttatcaa taatagcttt aatagtcatt
     8221 attaaaaaaa tagtggcaaa gagaagaggg atgaaaaatg aagaataaaa tactactttt
     8281 tttgactctt atttgcactt tggttttaac aatttatcct gcaaatcagc tctatcatca
     8341 atttaaaacg aaagagaatg tggcggaaat ccaagagaaa attgataaga agcaaactcc
     8401 ttcaaaagaa gaagtagcaa aaaatgtcgg acaaatacta tcgaataacg agaaccaaaa
     8461 agtaaacgaa acacaggagt cagataacga atcatttgat atggatgaag cagaaggaaa
     8521 agtcaatcca tatacaggag atgttttttc caagaaccaa acgaaagatt ttgaaccatc
     8581 tacctattca ggagcggttg gctatatata tattccaaag atcaatgtgc tagagctttt
     8641 gtttctaggc gcttcacagg aacatttata tcgaggtgtg gcgcaaatga gtgctactag
     8701 cctaccgtta tcaggtaaag ggcatcaaac agtaatagca ggacatcgtg gaggttatac
     8761 gtcaccacaa tttctttacg ttgatcagtt agtagcagga gatcacattt atatagatta
     8821 tctcggcgaa aaagcagtct atacagtttt tcgatcagat gttattaaaa attacggtca
     8881 gaattcaacg ctgactgata ttcctgattt ggatatgtta acactgtata cttgtcaccc
     8941 ttttcctcaa aactatgatc gtttattagt cagaagccta agagatgata aagcaaaata
     9001 catcacgcca caagtaacag ttgggaatac cgcatatgct gatgccattg atagtgaatc
     9061 cgtttcagct aagccagaaa ctgttacatc ttctaatgat ttatttgagg atgttgatcg
     9121 tgcaaacaag gaattagatg gaaataatga tcttaatatt ccggaacaaa ctagcgtaga
     9181 gatgcaagac agaacgtttg ctgaaaaggc aagttcaata tttacaggaa ttaccaataa
     9241 acatcagaaa atgcttttag tcatttggac tgtattagga gcattagcaa gtctaaaggt
     9301 tcttcttctt ttaatcaaag aatttagaaa agcataatga agattataaa aattgataga
     9361 gtacagtaaa aaggtattga tactattatt gatctctttt ttattttgaa tagagctaga
     9421 ttcactttta aataaaatca aagctgatct taattccaaa gaaaaagtca agaaaaaaat
     9481 aaaacaattt ttttaatcag aatatttatc agaaaattat tagaaaagat aatcttaaaa
     9541 gcttaattta ataggattat tggttgtatt taaaaataat gtatggaaaa gctataaatc
     9601 aatagataag atgcagaaaa tcttatttgt gaatgaaaaa caagtcatcg taaaatatta
     9661 ataggaggtg tagtaatggt ggtaatatca aaaacagcat tagactcatt agctaaagta
     9721 tttagtagca ggtttgatgg tgcagaattt gttgaatatc taagccaaaa cgaaagtgga
     9781 aaaactctga tcgaaacact gaaaaaagac tatttgaatg aaaatgactt tccgacgtgg
     9841 acgaatattg aagatgctac atgggatgta gtgtgtacga tatattctcc ttgggtaacg
     9901 attgcagatt ttgttttaga taaaattgga ggggatacat accctgatgc caaatctctt
     9961 gctacaagtg actttaaaac gttctatggt tatctaatgg gtctaatagg caatggaata
    10021 gatttgaaag ttacgccaaa acaaacacct gaagaaattg aaaaagaaaa aggagaggtt
    10081 caaatggctt atgcagatga cagagaaaaa gtaaaattat tggaaggtaa attatctgaa
    10141 gaagaacttg gaaaaatggt gcaagaaatc aatgaagaca gcaactattt tcctgaattg
    10201 aaggtatatc aaaacgacga agatttcttt aatgaaatgt ttagtaatag tccatgggaa
    10261 gcagtgagta aaacaaattt aggagaatgg aactttcaag atgatctagt tgcatttagc
    10321 aatgatgggt atttacgatc atattcagaa agtgagtata gagctgaatt aaaaacgtat
    10381 gaaacggata ttctgatgag ctatttaaat ctattagaga gtggtcaggg agagttaaga
    10441 gataaagttg aagaactatt aaaagaagag ctatagggat tatttcaaca taaacacaag
    10501 cagaaaacta ccaaacaaaa cgtaccatgc aaaaagccgg ttaaaccggc tttttgctct
    10561 attatgagag gagatcaaac catgagtgca acaaccgata tggctttaga agcagtaata
    10621 aaagataata caggaaatgt cgaaaatgta gaagacttta gcgatattgc aatcaatctt
    10681 tcagcgtgga tttcagctgt aggagaagaa aatatcgaat ttgagatcaa gaatatggat
    10741 gacttaaaag caaaatttcc ttttatcgca tcgaaactaa gtcaatttgc cgaggagaaa
    10801 tcgtggaatg aattagttag tttttccgaa aaaatttatg atattacgca agaagatgag
    10861 tgtgtttcat gggaaatgaa taatcaatac aagaaaattg atgctttcgt caaatcacgt
    10921 atagaaggaa cagcttttga gtttgaaggt atagataccg cagataattg gttaaataaa
    10981 gaatccttta ttaaaagtat agcggatgat cttgaaaaac aatggtctaa ggaagactat
    11041 gcagagtacc taaaaacaga aagagataca gaggtgaaag aaaaactcac tgaggtatgt
    11101 ttggatgaac atattgatcc caatatcgta aaacaagaag actatgaagt ggttattgat
    11161 aaagttccta ctgattttga ggaagttgta aagtatatag ttgaagaagc attatcgcaa
    11221 tactcttcag atgaggaagt ggacgaagaa actgttcgta ccagagtttg gcaactggtt
    11281 tttgatgaca aagattataa atatttgagt gatcaaaact cggttaattg gagtgtacga
    11341 ttattaattg atcaaaatga tattgaataa aatagagctg aaaagctcta ttttttttga
    11401 taaaaaaact agctattttt ttaaaaataa tttggttcaa aatttatttt tttaacttga
    11461 taattttttg ccatcctttt ttaaattggc tatatatcaa ggtttatagt ggggataaat
    11521 aaaaatacat ttgacaaaat ttacaatata gtttattata tatttatctt attatgataa
    11581 cacaataaaa ggaatgatgg tatgaaaaag aagaagttta gtcgatcgtt gttaggaatt
    11641 ttagttttag ttgcggttgg tcttagtggc aagggttact ttcagaataa cagcactcag
    11701 gaacatgatt ttcagatcaa aagtagtgtt caggtaggta ataaagcaga cagtgaatca
    11761 aaagaatttt tagggatacg ttatgatcca aacaaatatc caaataatat cgtaaacatt
    11821 aatgatggga aatatacact gacaaaagaa gaccatgaag cattatcaga aaaaggcagt
    11881 caaacctttt gggtaaatta tgcagattta gatcaacttg gaagagcagg agatgttgaa
    11941 gcgttgatca cctatgatgc tgtaaattct cactcatcta aaaatgtgga acgtccatct
    12001 ttcaaaagtt ctgtccatat tgcaggagaa tacaaggatg gagtatttga tcaagagaga
    12061 gatacttggg tcggcaaaga ttcaaacaat gaaatcactc agctagaagg atataaaggt
    12121 tatctctata acaaaagtca ttcattagca tggtcgctag gaggagatat ggaggtacac
    12181 aatttaacac ttggaacgag agcgcaaaat gttgggaaaa atgatcagaa tggagggatg
    12241 gcttactcag aaacgattgt acgtgatgca atctataaaa ataagaatga aaaagtattg
    12301 tataaagttg atccaattta taaagggaat gaattggttc ctcgtggttc tcatgtcaaa
    12361 gctttctcag ttaacgataa tggaaaaacg gtaaacctta atgtttatgt atttaacaat
    12421 caaaaaggaa tcaacatcaa ctatcaaaat ggtacttggg taagagatta gaaattgaga
    12481 aggtgaagaa ttggaaacaa taagcatcaa tggattagat aaatcagttg caaatcgaat
    12541 aaaaaaagga aatggctact atcttctgaa gaagggtaaa tattcagttg ctagagagtt
    12601 agaaacaatg agtatcgtgt atgtagctaa gaatcatttt gacgtagaac aggctatttt
    12661 tgatccagat tctgaaatag ggaaatgtgt tgaattatca gagaaaactg ttagtacaaa
    12721 aggggcgatg atcattgaga gagaaatgtt agacgaaatc agagtaatca ttcctaaaga
    12781 tacgcagatg tgtgaggaca gcataagtga cgatgaacca aaatcagaaa gaaaataagg
    12841 agatattcag atgagcgaaa aatccattga attaaaggaa tataagcgaa gcgatggaga
    12901 aaaatattat cctgtagcca gtttttctaa atcagtatat ctggttggac gtgcattggt
    12961 agttggtgca attggcatat atattttgca ttgggtaaca aaggttgtac aactgcttgt
    13021 agatacctta gtaagtattc ttgtctcgtt aaatgatgtt aacggaacag atgatttagg
    13081 attaaaagaa atgtttaaag agttactcaa tgcgtttttt cccaattatt taagttattc
    13141 atataatgta caaagctttt ttgcaaagct acacttggta gacatctcta ttttagtatt
    13201 agaagcagga acggtattct ttgttggata tttggttact ttgatgttca ggcatcacta
    13261 tggagaacaa agaccatttt ttgatgatat ggaaagtaga aggttgaaaa gagaagctct
    13321 agaagctatg gatgtgaagt atgatccaaa caagattata ggagatgaaa cgaacaacaa
    13381 aaaaagaaaa cgaaacaaaa cgcaattaga atccgatgtg ctatcaacgc ttaaaaatat
    13441 caaaatttct gttcatacaa gacgtgatct aagtgtcaat gaagacattc gagaatatat
    13501 cgtaaaaatc ccgcaaccaa aagggaagaa agttagagaa acagttttac gacaaattca
    13561 agatttaggg tcgatcctga caagagcaac aagcggacga gccaaatttg gtgaaaaaga
    13621 agatgaagtt tcaggcgatt atttcatttt ccgagcatca gtaaatattg aaagagaacg
    13681 taaggaaaga gtaagtacca aaaacaaaga aacggaaaga gcaacatctt caatcgcagt
    13741 ttcaaattca caattttctt ttccaatcaa tctctttgcc gataattcca aaaatatcca
    13801 aaaccaaacc gaaaaagcta gaaaatatgc cgaaactcaa aagcaatctt tagaacttta
    13861 tctatcttct gctgacgtac ctgcaagtct aacagatatg cacgttggga atacatctat
    13921 tgaatatttg tttactttat ctcgtaccag aaaaattcaa ctaagctcaa tgaaagaaga
    13981 aattgaaact tacttgcata tatcaggtgt aatcgtgcgg atcaacgcag ggcgtattca
    14041 aattacttta ccattaggag aaaatgatcg tattccaatt gatgtaccat caatgatcaa
    14101 tagcgtgttt tagaagacat cacaaataga aacagaaaat acaaactacc agttcacaaa
    14161 cagaaaagta ccgagaaaag tgaggaatag aaatggctat gaaattatta gagaaagtca
    14221 aaaagagagc cgaaaaagct gaatctattt tgctagataa agaacctaat ataaagctta
    14281 atggaaaatt cagtgtcaat atgttgaaca caaaggctaa agatccgaca gatgctattt
    14341 ttggaattaa gcctgatggc acaattgctc atttttgcat cagcgaaatg ccacacatgt
    14401 tggttgcagg aacgacagga tcagggaaat cagtattact gaatgaaatt cttgttacag
    14461 caatgtgtca ctcaacgcct gatgaattaa aaataggaat tgtagaccca aaaagggttg
    14521 aatttggaag atacaaaaaa ttgccgttca tgttggctga tccaattaca gatatggatg
    14581 aagcttatga tttttttgaa tatcttgtga tcttgatgca tgaacgttac aaactgatgg
    14641 aaaaagcagg gttacaaaac atcacgctat ataacgaata tgccgaaaaa aatggattag
    14701 atagatttcc ctatgtgatc ttattagttg atgaatattc acagttggtt ggaacacata
    14761 aagaagtaga aggtttgatt gttcaattag gacaaatggc aagggcagca ggtattcatg
    14821 ttatcttagc tacacaatct cctcgatcaa cagttgtcac tggtattatc aaagccaatt
    14881 ttccgtcacg tgtttgcctt atggtagcaa gtgatttaga aagtaggatc gtattagatg
    14941 aaggcggtgg agaaagccta agtccaaagg gagatatgat tattaagctc gttaatggaa
    15001 gtatggttag agcgcaggga gcttacatca gtaacaaaga aattgaaaca attttcaatc
    15061 accttagaaa tactatgcca gaaccagaat atgttgatta ccgagcaatc gtagctgaat
    15121 ctcgtggtga gggtggagaa gacgaggatt ttggtggaat tggtaaagct cctgtaagaa
    15181 aatctgctaa aagaaatttg aacacacctt tagcaaattc atcatctaaa gagccatcaa
    15241 ttgaaaagaa gagtacgttt gctctaaaac ttgaaaaaaa caaagaagaa aaagaaaaac
    15301 aaggagctaa aacactagaa aaacttcaag ccgaaaaatt agaaaaagtt ttaaaagcat
    15361 tagataaagc tgattctgaa ccgcaaacct caaacaacac gaataatgaa cagccgattt
    15421 catctaaaac taaaccgaaa actactgatc cgaaagtttc agtaaacgtg accatcacaa
    15481 ccgataagtc tgagaagaaa caagtaaacg gaacgacttc acctatcatg caaaaaatgt
    15541 tgaaagccaa aaaacaggtg cataaatgat cattgtcagt tcttttttga ggtggcttac
    15601 gccatataaa tatacagatg aagtagttgt gaaacgaacg aagaaaagag ataaaaaagc
    15661 ggtactaact cctaaacaga tgcttgatca tggcatttta ggggtgaagg ttttagaagt
    15721 gaataaaccg tttgaatcaa atagtgcaag agaaaagttg cttggagctg aagccgatgt
    15781 cgcatatttt taccatgaca aaagcaagca tcaaatatct attaaattca atccaaaatc
    15841 ggcatggcgg tatcaagcaa gagatgactt gaaacgtagg aaacttagac caatgctcta
    15901 tccagaagga aaagaagcat ttgatagaac ccacatcgtt cccattggtt ttcatggtac
    15961 agaatcagat aaccgcctat tagtaggttg gaacagcaat caaaatagag ttcagatcaa
    16021 taaatttgag aagaaagtaa ggaaattcaa cgatcgaaaa acgatcctat ggtttgcaga
    16081 tatttgtaaa cagccggatg gaacagcaaa gtgggaagcg gtgatatttg acgaaaatgg
    16141 taaaaaagta atgtctgaaa catggcatga taaagctaaa tttgtttggc agtagcagta
    16201 gaggtgaaaa agattgctag aacttcttga agcaaataga acaggcttta atcaaaaatt
    16261 agaagtggga gaaactatag aatataaaga taaaaactat attattatcg gaatctataa
    16321 cacgagaatt aacagaatag gtgatccacg tataaccagt gacttggttt gtcaatctgt
    16381 taactattca cctgatctga caagcaggta taagaaatac gtgttattag aatatagaca
    16441 caagattact gatgaaattg gtgtaaacaa cacacgaaac atatttaaga tcggaacagt
    16501 gattccttat agtaacaacg aagaaaaaat attttatcag atttacggaa tagaaaagtt
    16561 tgaatatgaa catgtcgatc tgctagtgac gtaccaaatg cgtttaatag aaccttggtc
    16621 acaggtagaa attgataaag cagtaaaatt gaaccgatta tcaaaattta acgtattagg
    16681 aaatgccttt taaaaatcgc aatacacaaa cagaaaaata ccaaaaaatt agcaatgaac
    16741 gtaggtaaga acatgacaat aaataataat aaccctaaaa aatataatgc tcttgtccaa
    16801 tgctatatcg aaaacaaaat tacaatgcaa gaagtcgctg atgaattagg caaatcaaag
    16861 agcctagtat cacacgattt taagcacaat gtttttccga acccgattga gctgaggaaa
    16921 aaatttcaaa agagagttta tcaagaaata ggtaagtgga ttgatgaagg gaatgcaatt
    16981 gaccctttaa ttgaaaaata tcctttttta aaaagcaaaa ataaaattca aaggttaatt
    17041 cgtcaaggcg atattcaagc taaagaacct gttttgacaa ccaatgattt ggctaaaata
    17101 aatcttcata aacaaattat tgaagacttt gaaaaaaatc tttcaacaac tgaaatttta
    17161 aaaaaatata atattccgag aggaaagcta acatcgactc tttttagaga atatggagaa
    17221 tcggcagtta ctaaagcaaa ggaagtagcg aatgagagaa aaaaacaaaa atagtagtcg
    17281 atacctagta gcgactgtag tttttgtttg tgtattgatt ttcctgtttg attttttgca
    17341 gattggagaa agcataattg gaaatacatt gagtgcaaag gaaatggttg ctttaggtgg
    17401 tttgtatgaa ggacacttgt tcccgaatat attcatttct atcgtttctc atattaactt
    17461 gtaccattta atttctaatt tattgttctt agtagttctt gaagaagcgc tgaatgatca
    17521 gtatgagtgg ttaacattat tgatcgtttt aatcatatca ggatttctag gaagcttagt
    17581 tccttttctg ctacacagca acatcgtaag tatggggctt agtggaggta tttttggatg
    17641 gattgcttta tttgcgattg catacatccg ttttgatagc aagaaacatt tattactaag
    17701 tgtttttgta ttattgataa tcggcatttt actggtatct acttttgaat caggcgagac
    17761 aaacgtcttg tcacatgtaa tcggatttgt ctgtgggatg atcttgggat ttattctaaa
    17821 gaacgtttca ttgatcaaac aaaagaatta aaagggagtg ctaaaaatgc caaaaaaaaa
    17881 agaaaagaaa attccagtgt ttttgtctgt ctcagaaatg ttatcacttc aaatactgtt
    17941 aagaaaaaag attgaaacaa tagacgaaga agttagaaat aaaagggcta tgtacgaaca
    18001 acgtgaagcg ctaagagaac gaatccacta ttttgatgat atacacacta aaatctatga
    18061 agcacgtaca aatcacgaag acgaaagcaa attaggatta gctcaacaac gaatatttga
    18121 atggctgaat acgaatactg agcaagaacc gttaagagca attagtaatc tttttgaatt
    18181 tggaatgaag cattggttta acgctgtaga aaaggatgct gacttacaag aagcgttcga
    18241 tacactaagc gaggatagca aatccatgcg agacttattg atcacttatc taaatgagca
    18301 tgaatttgaa cagacgaaag ttaaaaagaa aaataaaaaa tagaaagttg tgatgtatca
    18361 tgctgtttac cttattaggt tatttatgtt tagttcttgc tttttttgga gcaattgcta
    18421 tatttgtcgg tcagtttcaa gcaaataatc cgataatgcg taacataggc attggaattg
    18481 ttatcatatc cttgattgta tttggtgcca caaagatttt tgggagtaat gatcagcagt
    18541 ttggtatttc tggagttgat aatagttatg ctccagattc attgggaaga gtagtgatag
    18601 atggaacgtt tgagaatgta acgagctaca aaaatgtttc attgacagtg aaagaagatg
    18661 acaagaaagc atcagatgac gttctcgcta cgatcaagcc gtctcaatca cagtttgaag
    18721 tgttttatac agtcaaagag aataaccctg tacgcaagct aacattagtt tttaacgttg
    18781 acggagaaga atactataaa gatgtaaaaa tcaataaagc atcaacgaaa aagattgtcg
    18841 aatcagcgaa aaaagaagta gctacagaag aaagtacaac tgaatcaagt tctactgtcg
    18901 aagttgaact accagataaa attgattttg atcctgaaaa agtcaaatcg tttgaatctg
    18961 tttctggttc tatggcagat cggtttaaca ctgaagtttt caaagctatc aaaactgtta
    19021 aattggatac tgaaaagcaa aggattaatg ttaccttatt caattcagtt gaatctatgg
    19081 atcaggataa aaaagttacg gttgcaagag aactaggaaa aagagtaatt ggtttgtatc
    19141 gtggtactgc taaaccagat tcagacggtg cagatttacc agttcatgta gtttatgaag
    19201 acggtaaagt ttttggagat tctacagcaa acgaagcatt aacgattaaa ttggctaaat
    19261 agccagaaag ttataataaa caaatgatgt cacaccaata atatataggt gtgacacctt
    19321 ggagatgata gctgatggta gtaaataaag aaaaagttag aaagtatgtg actttaaaaa
    19381 tagcttctgt taaatattta gaaaagcgag ctaaagaaga agaaagagca agaggtaaga
    19441 aagtaacagt ttcagagttg ttagaagaat tgatcgagaa tgatcaaaca ataagacgtg
    19501 catttactaa taggtctatc agataacaat ataattaata aaaaagaaag agtgatttgg
    19561 tcttagacta aatcactctt tttatataaa gtttctttac acttattccg aataatgtta
    19621 aaattcttta tacgatatat agttacttgt cagagaaaga gataaccagc aatattggag
    19681 ggataataag tggaaaacaa taatgatatt agacatttta gcattgggga aagagttaca
    19741 acagtaagtg aattatcaaa ggattataga gataaagagg gaacgattat ttctcttaat
    19801 aagaatcgaa gaggcgtttg gcaatatgtt gttgatttag gtgatggcgt tacagttgag
    19861 tgtaaagata gtcaactgat cagaaatgat ggcagtcatt ccattgaaaa agcaattctt
    19921 gtatacccaa aagtatcaag taagatcatg aatgactggt tgcttggaaa atttggtgag
    19981 tacaataaaa aagaaatcgc agaagtgatc ggcaaatctt atccaacagt attagggtat
    20041 ctaaaaaaga taactaacaa agaagcgaaa gttgaggatg ttttaacagt aagagaactt
    20101 cagtcattaa tcgaatatcg gaataaacaa ataacaaatc ctgagtacct taaaaaagaa
    20161 gatggtctat tgaaacaatt ggaacaggta aataaaatcc ggaagatgca aaaggtagct
    20221 cctttaagcc tagataactt taaaaaaatt tatttgaaag agatcgaaaa agactaatgt
    20281 ggagtgtcac tttaccgttt caacctgtat ctgcaccaag accaagtgca agaaggaatg
    20341 tttctgatgc aactaatgac gtagcagaga aaaggatttc aacctattat gataaaaagt
    20401 atctcgatta tttgaaaaaa ataaaaagct ttatcgaaga tcaaggtttg ttagatgatg
    20461 aattttactc gatcgtaaat gatccgatgg gtgcaattat ggaagtcgac ttttactatc
    20521 agataccaaa aagctataaa aaagtctata acattatgaa gacgacagcg ccagacttag
    20581 ataatttagt aaaaagtgct atggatggta ttttcaacat ctcagctata cgagatagcc
    20641 atatcacagg cttaattgct tttaaatata atgtggcgaa cgaaggaaaa acagttgtga
    20701 ggatcaaacg atattcagaa tttgagtggg atacttctga aggattgaac ggagatatat
    20761 gggaagctac atttgatttc aaaccagtag caacgccaag accaaagtct aaatttagag
    20821 gaaatgggat tatcacttac tatccaaaag agtacaacga ctatttggaa aatatcaaga
    20881 atacgcttaa agagaaagat ttggtaaatg atcaactgaa aaaggtaatg aatgctccta
    20941 tgggggttat agctcagata gattattttt accaagtgag aaaagataag aaaaagcttg
    21001 attcactgat gcgtacttca cagccggata ttgataattt agtcaaagga acattggacg
    21061 gaatttttaa caaggaaata ggcatcaaag atagcagggt tgtagggtta attgctttta
    21121 aatacaatac ttttgaaaag tcgaaaacaa acgtgagact acaggagatg ggctgatgaa
    21181 taataatgaa aaaattcttc atgtacttga tagctttgaa acaattcaag aagaactaaa
    21241 gaaatatcgg gatgttttgg aacaaagata tgattttgtc aatcagcaaa agagtaatca
    21301 catggatttc attctcaata tgaatgactt gaagaagaaa ttagttgaac gaaaagaaca
    21361 agaaaagttg atcaaagctt actttgaact cggtgaaaaa gaagttaaaa aggcaatgga
    21421 actgaatgaa gatcgcaggg ttttagatca gctgttagaa caattattgg tgatgtttca
    21481 aaaaggacga atagatgagg atttaattga agaagggttg agaaagtatc cttcaaactc
    21541 aggtatcgga atagtgctga aagcgattga tgaagaagaa attgaagctt tcataccgcc
    21601 agaggatttt gaatcggcaa tggaatatat aaaatattat agccaaggga tcactgcttt
    21661 tagagagttt gatcctgaag atgttattca tgacttgaac aacctaaaag aatggtgtga
    21721 aagttatgaa gtcgatgatt ccggattgga ctacttgatc agtattatgg aaatcgaaga
    21781 agagatgccg gataagcctg atccaacaga tattttagaa ttgatccatg aagctagaaa
    21841 tccaattgcc tatatttcta gaggatatac tgtattggaa tactataagc cttatatatc
    21901 agcgatgaac catttaagac gtgtattaag ggaaaaacgt gaataccgct cagtgttgaa
    21961 tgcaacgaat agattagaaa aagctgtttc agagctagat gcttattatc gtgaacatta
    22021 cctgcaagca ggtggtatgc caagaaatac gaaagcaaat atcagtaggt atataaaaaa
    22081 agctgagtag gcggagttag cccgtaaaat ggcaaaaggt aacctgaaag gggcattttg
    22141 aatgaaaagg gatgtttttg aattgtacgt attagaacgt ctagaagacg gcatgatggc
    22201 acaagagata attgatgaaa ttgatgatat gatcagcaga tttggtcaat tggagttgaa
    22261 tgacggaaac aaaaatccgg tagtgctaaa acaattttgg ttgaacaatt tttcgtataa
    22321 ggattttatc aaagaaaagg caaatacatt gtactgacta aattcacgag gagcagtgat
    22381 gagagcttat tgctaagagc agttaggctc ttttttttgt ttgtgtaaaa ttatttgttt
    22441 tacaatacac atttatacac aaaaaatatt gacggatagt acacaaatgt ggtaggatat
    22501 atttgtaagc aagttagatt aacaagttaa aggaaggaag agcagttatg aaaaaagaag
    22561 aactaataga tatatttcaa attgttgaac gagcaaataa tatgggaatt atgttttttg
    22621 atcgtatttc tttaaagatg gatttaagcg ttgcccacca agaatttaat ctacgattaa
    22681 aagccttgtt gaattctgat gatgttaatt tcgctcatga tgttgtaggc atacagaacc
    22741 atatagatag agaaaacaaa cgtatgggtg atggattctt accaagatat tcaagtttat
    22801 aatttgaaga aagattcaag agtatgtgtc attattgata ggtactcttg aattggaaag
    22861 gaggaatgaa tttaagacaa caacgattat gatcttaaaa caatcgttta tgtaattgac
    22921 aatcttacga ataattttca tgcaataatg acaataaaaa tgaaaagggg taaaatcaaa
    22981 tgaaaaaaat tttagtagga attctattca caatggggct agtgctatta tcaccttcag
    23041 tttcagcaga aagctctatt tccatgtatc gtatgtacaa tcccaatagc ggagagcatc
    23101 tatacactag aagcgttgga gaaagagaca atctgaaacg ttatggatgg cattatgaag
    23161 gtgtcgcatg gcaagctcca acaagcggta ctcctgttta tcgtttgtat aatcggtata
    23221 acggtgaaca tttttacacc attgatgccg gagaaagaga taagatttcg cacacaggat
    23281 ggacgtacga aggtgttgcg ttctattcct acaacggagc aaatagagtt cctgtgacac
    23341 gcttgtacaa caaatacgtg aattggcatc attacacgtt agatcaaaat gaaaaaaata
    23401 tcattagtcg acaagggtgg aaaatcgagg gaactggttg gtatgcaatg ccaaacagcg
    23461 caccaaatcc tgcacctgct ccaagcaatg aaaaagtgtt aaatgttcct gtcatttggc
    23521 aaggtaatac gatgttgtgt gaaggtgctt ccctgttaga gggattgcac tacaaaggag
    23581 tagcgacaaa tcaaaactta accagttttg taaactatat gccaagagct aatgacaata
    23641 atccatatca tggctattct ggcgaatggc gctacaacgt aaatggtacg tatcaaggca
    23701 tgatgcctga tccagtagtt aaatgggcaa aaaatgttgg tggtaatgcc gttaatatca
    23761 ctggttcagg aacgaatggg atcaagaatg aaattcgcaa tggtaatccg gttgtaactt
    23821 ggattactta taactatgcg acgccagagt tcaaacaaat gccttggggg cgtgccgttt
    23881 ggaatgggca tgttgttttg gtagacggat ttaagaatgg cgcttaccat gtagtcgatc
    23941 ctgtatttgg agcaaaatgg atcaatgcag gcacgtatga aaaatcgttc aatgtaactg
    24001 gcatggcggt tgctgtacgt taattgatag aattaataaa taaatgaaat aagagcttaa
    24061 ttactgaaat ggtaaatagg ctcttgtttt ttaggaaaaa actgcttttt gtaataagaa
    24121 tatataacaa aaaaattgaa tttagtacac aaaagtggta tattaaaacc gtagagatta
    24181 tgcgaagagg taattttgat gaaccaaaga agaagaaaaa gactagaaga aataagcgag
    24241 cgactatccg agttaaagga tgagttagaa gtaattcaag aagaagagga agagtacaaa
    24301 gaaaatatac ctgaaaatct acagggatca gaaagatatg aaaaagcaga agaatccgtt
    24361 gatcaacttg aagaagctgt tgatggttta tccgacatat tagaattgat tgaagatata
    24421 gctagctaga gatgactaat gaagatttca ggagtgagca aaaaatgatt gatatttcac
    24481 tgatagaaaa gctacttttt tcaaataagt acacagccaa agagctggct acaagatggc
    24541 aaatatccga atcagctatt aaagcctatc gtcaaaataa gggaagcgta ggatggcgtg
    24601 attggaaagg aatcagcatt ggaaaagcag aagagataat gaaacgtgaa ggatttcaaa
    24661 ctgacaatga ttctaaaaaa gttgaatagt ttaatagtcg ccaagaaaag taccagggcg
    24721 aaaggtagat tacaaaggaa aacactttta aataaacttc gcaaaagcat caggttatga
    24781 gtggctaggg ctatacgaat gagatgaaaa caaagggctt taatgtcaaa gaaaacgcaa
    24841 taggggggaa taaaattttt aaaaaagata tttatgtttg gtttaatgga aaaaaatata
    24901 tgactactaa caaaaggtgg tcagagctag tacaaaatac agttaaaaaa gtcatgccag
    24961 atggatatca tttcaactat atacaatgct cacaaacaac tgaaagtatt tatttttcaa
    25021 tattaaatga gaatagactc tattatttca gggtaagttc acaccatagg aaaaagaggg
    25081 aagataatgt tacgacattt ttatcgggaa aatacaatgg tttcaaagag ttaagtgaag
    25141 caattggtga gtatctaaaa agtaatagat ttgtcagaat ttctgacaaa catatattga
    25201 tcttgttact ttatttgaat aatagcttca aattgttttg gagagacgac actttctact
    25261 atatagagaa cggcatggat atttattctg gtatcaacgg cacattaaaa cattatatta
    25321 aggcgttact tcgatatggg gttctttatc aagaagattt aagtaaccaa attaagatta
    25381 gtaattctgg aaagtcatta ctggcaaaat ataaaaaatt gctttctcct atctacaaag
    25441 gaatagatat ggaagctgta aattctgaaa ctttatttaa tttagttgtt gatgaaaagt
    25501 ttgcgaatga attttttaaa agtaaaaaaa ttgaaagcct aaataacctg tttcctgaaa
    25561 atgcaataaa agcttatgta gataataata aatcacgatt atacaactgg tttattccca
    25621 aacggttgcg aggaaaaatc aaaattggcg atcaagtgaa agtaattaat ctaaatcata
    25681 ctaagatcgt taccgtaacg gagttgtata tagctgaaaa agaagagatt acaaaaatga
    25741 aaccagttat taaaatacta gataacaaag agtgagtgga atatatggta gcaaaaaaga
    25801 atactctaaa agaagcttct gaaaaatatc aagatatgaa aagacgagga ttaataccaa
    25861 aggacaaaaa aggtatatgg agagaatttg ttaaggaagt cagtagtgat cgaagtggcg
    25921 gtgactttgt tggacgatat acagcaaaag gttatagcag gcgcttaagg atcactgttg
    25981 aatatggaac aaatgaatca gctacagagc tgaagcaaag gtacttagat acacgaagag
    26041 aagcttcaaa aaaatatgat gatttcaaga gcagaggtct aattcctaag aagaagaagg
    26101 ggatttggcg tgagtttttc aaagaagaag atagcaatcg gaataaggga gacttcattg
    26161 gacgatacac agcaaaaggc tacactaaga atttagggat caaggttgaa tacggaactg
    26221 gtgaaagttc atgggaattg aggaaccgct atttaaatac attattggag aaatacaaag
    26281 cagaattatt agagctgttc gatgttaatg atttcataga gatggctgaa aaatatggtc
    26341 atgaagaagg ctttatgatc aatgacatta tggttattga taattttacg gacttattag
    26401 gacttgcgaa aaaagcaaga gatttaagag aaacacagat gtatctattc agaaataaaa
    26461 acggaagaaa ccggagaact gaatcgagcg agatcgaaga ttactatgat gcctttacac
    26521 acgatctagg agcctttgta gacgagatca gtggtgttat ggacaaatat agggtctaga
    26581 ataaaaaagc cggagatgag caaataaatg ggaaataata gcatatatac acctgaaatg
    26641 cagaataaaa ttaaaagact tgtcggatta gggtggatga caagaggtaa gttagattct
    26701 tttagtacga tcaaatatct tttgatggat atctaccgcc aaaacaagaa aacaggaata
    26761 cattttttgg gctatgataa gccggaagat gcgcctttct ttgttcctag ttcagcctat
    26821 agagccagta cttccggtag catgtataac ttggatttgt ttgaggaagg agcaaagatg
    26881 atcgaatatg attttaacga agcctattcg aggatcatga gaaattatcc tttgccgtca
    26941 aacacttatt tgaaagcaaa atataataca gatcaagcta ttttgagagc gataaataga
    27001 ccaaaagtaa gaccgtatga aaatttaaaa acgtatatgt tctttttggt taattttgaa
    27061 ggaacagcca aagaaggaac gtatgctaat ccaaaatcac agtcgatgtt tgcggattat
    27121 ggcgaaaatc ccaaaacagc taatgagcct atttggctat cggagattga gctaacacta
    27181 atccttgatt attatgatat caaagagatg gaagtcctcg atagtcacac atttttgacg
    27241 aaaaaaggat tactcaaaga atatttcgaa agaatcgaac cattaaaaac tgatcctgat
    27301 acgttgaaac tttataaaaa tcttagaacg aaagtatttg gtgctatcgg acaaaaatca
    27361 ttaagagaag gagaaacaaa caccttcgat aaatacagta tgtataatcg agcgtattcc
    27421 tccatggtag caggcgtatt tagagatcgt atggttaggt atgaacagaa atacgttcat
    27481 agcgcatatg ggctattaaa aatccgtact gatggattgt atttcagatc cgaagtacca
    27541 gagtttgaag agctgtataa acttggagta gttaagaaaa aagttcatac aatatccaaa
    27601 gaagaagtcg aaaaagcttt agaatttaaa aacaaaggat ttgaaaataa gggctccttt
    27661 gggaactcta aagatgaagt taagggtgtt gtgatagacg atgatttcga gtttgatttt
    27721 gactaaatac tctttggaaa agatggtagg aggtaaatat gaagaagaaa attgtggaag
    27781 gaaatgtagg tgttattatt ctaaaagatt caactgacta tgctaaatca atggcactaa
    27841 aagacgaaaa agttgcacgc atggataaag atttagttga atttctgatg gatgatacag
    27901 aaagattaaa aggggatcag tttttgagtt taatgaaaga caaaggctta aacacatatg
    27961 gtttatttga ttataagaaa ttagctatag agtgggtaaa agaaggagaa atatttttta
    28021 ttgaagaatg ggaaggtact gagaacttag ttcttcatca gtatcttttg aaagcttaat
    28081 ctaagtaaaa cagttctgac tagttatgct tgtcagaatt tcaaaggatg ttttccataa
    28141 ccatcatcat tcaaaaataa aggatttgaa aataagggtt cctttgggaa atctaaagat
    28201 gaagttaagg gtgttgtgat agacgatgat ttcaagtttg attttgacta gatttttttg
    28261 caatgtttaa gagtaaacaa ggtaagaact aagatcatga agattgagag taaagaagat
    28321 agaggacgaa tgtatgagaa cacactatat ttatttagaa gataaaattg tagatgaaat
    28381 tccggcaaaa agtcgagaac aagctagaaa attatttatt gaaaaataca aagaaatcaa
    28441 tggagatagt gaagttcaaa aagtggtcgt aacagttaga aaaaggcaaa caaaaaagag
    28501 aagtacgttt catgtcagcc ctgatatata taatcttata gagcgacata gaagtgaaga
    28561 taatatttct atatctcaat atattggtac agttattgat gaattgattt caggaaaata
    28621 tgactatgct tttgattttg agaatgaaaa ggattaccga agtgttgctg tctttcaatc
    28681 tgattttgag aagctaaaaa actatgctgg caggagaaat gttaattttg caagactact
    28741 agaagagttc tactccgaag agttgggagt aggaaatgaa tacaagagag aaacttatgc
    28801 gaaattgtct cataagttat cccaagcgct taaagaagtg acagaagtta aagcggaact
    28861 agatgctaaa cttgaagaag tgaaaaaata tcaaacagag aggaagaaca acatgaagaa
    28921 tcaagtggaa tttgacgaac agaaagaatt tgaaaaagca agaaaacgct ataacaaaat
    28981 tatgaatgaa cttagctatg aacacttaac agttcatgaa gaattgagtg agggtacaga
    29041 aaaatatacg atcgcagata tggttaatga agtggaaact cttttagctt ctttctttga
    29101 aaatggtcac gtaaacgatg aatggcgaaa agaagaacct aaaagggtta acgcttatat
    29161 tgctcgatta aaaaggttta ttgataaata taaggagaat agtgacaaat tttctaaaga
    29221 taaataagga gagagtgtga ttacatttgc cagaaatcga aggaatattt tcgccaaaaa
    29281 taggtaaaaa acagttagat ttcagcagtt ttccgagcgt aaatagagat tataatctag
    29341 gtgatgaggt acagatacta aatattgatt tcaaagaact agacttcgct gttgctgttt
    29401 ccaacaaacc caaggcgttg gaacgagtga aaaaaatata ccaagagaat gatcaaaata
    29461 tcaaaaatat gatcaaaaag tatagacgag ataattcaaa agttgaagac gttttattca
    29521 acggtacggc aaaacatgat ttgaatgttt atatggcatt aggagtggct ttgtactgta
    29581 attcaattaa tcagacagat attttggtta atatcgtgag gaatagctat caaaaaatat
    29641 taaaaataag tagcgaaaca aacccttatt atgcaatgaa atatcttggg gataatttat
    29701 taaatgataa aaaattgatg cacaacactg aagagctgtt atctaatttg gctgcgatta
    29761 actttctatt caaaacaggt tctgaagatt attttataga taacgtacta aaaggtgctt
    29821 acggaacagc attttatccg ctttacaata tgaaacagca taaagccgaa caaaaggata
    29881 acaaacttga aattaaaaag atgaaagaac tattaggtat aggatttgta aagcccaatt
    29941 caaaagtcac tattgcttcg ttagcaacta ctaacaataa tgggaaaata gtaaatgggt
    30001 ttgacgattc agatatagat atattgtcaa aatcatattt ttctttgtat ggagattttg
    30061 cagatttgat gggtattgat agttacttag tcaataattt tgagatcaag ggtagcgagc
    30121 tgaatgatat tgtgtatttc gttttaatct ctctatatgc aattgatcag aataccgagt
    30181 accgacaaat tgactatttg ctagtttttt atagtttgtt atatcagttc gttttaactc
    30241 ggttgtttaa aaatgctaag gaagaattga tcctgaattc tgattatgaa atagcaaaac
    30301 aaattgcaag tattagaaaa gaaaacaaat ctgaagtaat caaattaaga aaagaattaa
    30361 gtattgcgag taaagaaaac ggtcggttag aatctttagt caaatcggca aaaaaagaag
    30421 aggaactttt gaagcaagag attaaagaat taaaaggaat cagaaaagaa cttgaacagc
    30481 tgaggtttga aaataaagta ttaaagcaat tgcaggagca agaacataga caatcattaa
    30541 atggtaaaac tgaagagcct tcactgtctg aaatgatagc ttatctaaaa cataaaaaca
    30601 ttcttttagt gggaggacat gtaaattttc aaaataaatt aactgaacta ttaccaaata
    30661 ttaaaatgtt tgatgtaagc gaaaataatg gaaagatact taaaaatttg aatacgtgtg
    30721 atgcgatttt tctatataca gattacttga atcatggtct atattatcgt gttatgagtg
    30781 aaatttctaa taaagataag atattttatt tagataatca tgtgaatatg agcttaacaa
    30841 ttaaacgtat ttatgatctt ttatatgttt ataaacatta atgaggtgtt aaaattgaca
    30901 acaataacta tgacaaaaaa aatagaagta tatgttgatg gatcacaaga agaaagggat
    30961 tccttttttg attttttttg gaaaaatagt agagaatatg taaaagcgtt gaatctggta
    31021 tataaacagc taatgtttga agagttgata aaagatgcaa ttaaagaaat ggatcaaggt
    31081 tatgctgaga gagaagaaag tattcaaaat cggattgaaa agttagcata tactgatcca
    31141 atagatcaaa aaaaacttga taaagcaaaa gctgaattat ctaaattgag aaatgaaaaa
    31201 aataaagaag cgagagaaat attaacgcaa gcgatagggt tgaagagtca aacgagaaca
    31261 cgagatgtag caaaaaaatt agactttgac tttggagatt ttgttgattc cgcaaatatg
    31321 aaagctagta aagattttgg caatgatttt atcggaattg tgaccggaca aagaacgcct
    31381 agaatatata aaaatagaag taaatatgga ttattacctt ttagaggtcg agatattaaa
    31441 atccataaag atgataagtt ttatatttat ttacctaaag gctttaggtt taaagtgaat
    31501 ttaggtagca agccaagaaa agcaagagat gttgcttcag ttttacaaca cattatggat
    31561 ggcgattaca aattaaatca aagtaatctt atttttgatg gaagaaaatt attttttaat
    31621 ctaacaattt cttttgaaaa aagatataat gaactggagt tcaaggaagg taatgaattg
    31681 atcgtaaact ttgcagattt gtgtagcggt gaatgtttag ttaataataa atcggtaatg
    31741 tcttttggtg atagccaata tataagaaac ttcaaaagta aaattttagc aatgaaatca
    31801 aaagaacaaa gccgaggagt cttttctaaa ggcggtcatg gtcgaaaaag aaaattagat
    31861 caagatcgat gggaagcaat aaagaaaaga gaaagtaatt ttgttaaaac ttataataat
    31921 caatgttctg caaaaatcgt taaaactgct attcgcaata aagctcaaat tattcgtatc
    31981 attgaaccag ataaggctta tggcgaatgg gcttactatc aattgaaaga acaactagta
    32041 aataaaggaa aaagatatgg gatagaagtc agaagttagt aaagtaaaca atcgttgatt
    32101 tggcaacgaa atagtgaggg aaaatccact cactgaaggg taaactccgt caagttgtgt
    32161 gaccagacgg aaggacgagc gttgttgggg ttttagaacc atataaaaca gcatgtttct
    32221 caaatgagta ctttaaatta attgatggcg ttcctgcttt agaaccatat aaaacagcat
    32281 agttctcaaa ttgtttaaaa tgattgtcaa gttaaaaaaa tctgggatca tataaaatag
    32341 tatagttctc aaatatgatt agaaacccta ttaaagagca atattaagcc aacttactta
    32401 aatcgtttaa ttaagaacag taatctcttt tagtcagact tttagtctga cttttttgta
    32461 tttccaaaat ttattcttta caaaaacgaa catatgtttg tataattgct tgtgaatggg
    32521 ggaataaaaa tgtttgatta cagtagagaa ccggtgaatg actatttttt aatcgacatg
    32581 aagtctttct atgctagcgt ggaatgtatt gaacgaaatt tagacccaat gactacaccg
    32641 ttaattgtca tgagtagatc ggacaacact ggttcaggtc tgactctagc ttcttcacct
    32701 actgcaaaga aaaaatatca tattactaat gttagtagag ctactgattt accttatcca
    32761 ttaccaaaag aacttcatat tgttccacca cgaatgaact tatatataaa aaaaaatatg
    32821 gaagttaatc agatttttag aaagtatgtc gcagatgaag atttattgat ttattcgatt
    32881 gatgaatcaa ttttaaaagt gacaaaatcc ttaaatttat ttactagttc aggaacaaga
    32941 agcgagagaa gaagagaatt agctaaaata atcaaagatg agattcagaa agaaacaggt
    33001 ctaatagcaa cagtcggaat aggagataac ccattattag ctaaactcgc actggacaat
    33061 gaagcgaaga gtagtaaaga atttatagct gagtggtctt atgagactgt acctgaaaaa
    33121 atatggaaaa taaacgagat gactgacttt tggggcattg gatcacgcat gaaaaaaaga
    33181 ttgaatcata tgggaattat gagtatagaa gatttagcaa attggaatcc ctacacaatt
    33241 aaaagtcagt taggtgtaat cggacttcag ttatatttcc ataccaatgg aattgatcgt
    33301 acggatattg ctattccacc agaaccaacc aaagaaaagt cttatgggaa ttcacaagtt
    33361 ctaccaaaag attatacgag gagagaagaa gtagaactag tagtcaagga gatggcagag
    33421 caagtagcca ttcgaattag acaacacaat tgcaaaactg gttgtgtacg cttagcaatt
    33481 ggtacgtcaa ttttggaaga aaaatcaggt ttctcgcacc agatgaaaat accaattaca
    33541 gataatacga aagaattaca aaattattgt ctttttttat tcaataagtt ttatgagggg
    33601 caggaagtac gacatatagg agtaacttat agcagattag tatacacaga ttccctacaa
    33661 ttagatttat ttagtgatcc aagaaaaaag attgctgaag aaaatttgga taggattatt
    33721 gataaaatta gacaaaaata tggatttaca gctattatac atgcttcatc tatgttagaa
    33781 ggtgcaagaa gtattacgag aagcacttta ataggaggac acgcaggagg attaggaggt
    33841 ttgcataatg attgaatata acgatagagg acgtttaaaa tggtcgggat tttatttgtc
    33901 tgatcatact gaaagaatca atgcagacaa tgtacaacgt gctaatcata atttggcaaa
    33961 agaacaaatg acgactgaag agattgcgaa aatactgaga actgctgtca taaaaaatag
    34021 acccgtctgc attcaaaaag aggaacgaaa cgctgaaggt tactatccag atgatgtagt
    34081 aggaaaaatt attggatatg acgagcttgg tgtatttgtg gaagaagaaa aagttcacta
    34141 tgatgaaatt aggaatgttt ctttcgcgga attattaaaa tggagtcaga tatgaacatt
    34201 attaaaaaat acgaattcgg ttatattacg tatgaacagc taatagagga attatgggga
    34261 tatggtcaac aattaattaa tgaagtgggg attgattgct tttgtttcta tattgaatcc
    34321 ggagcaggat accataagaa cagatactat atatttccat atccaccaaa atagtctctt
    34381 agagattttt aaattttctc caaatacttt caattattgt gaaatatttc cttttaatta
    34441 atcaaatttt ttataaaagt aatatataaa ataaattgct tgaagtatta tatttagata
    34501 tcataattta tggaagaaaa attaattaaa aaggatgaga ttataatggg gttactggtt
    34561 ccgagagcta atacttatac tataccttta acgaaacgcc aattaattgc taaaagatat
    34621 caaaggatta ctagagccat caatagagag ttttggaatt ctgaaagtga tactgctcac
    34681 agtttatacg taggttctta tgggagagga acggcaatta gtactagtga tatagatata
    34741 atagttgaat taccgatggc agaatttgac agattcaaaa attatttatc aaatggcccg
    34801 tctaagttat tacaagttat aaaaaacgca tttcaggaaa tactaccaaa tagtgatatt
    34861 agagctgatg gacaagttgt taaaataaat ttccatgatg gaatcaaatt tgaaatagtt
    34921 ccagctttta atgaaaaaga ttattggggt gagtcaaaag ggtttattta tccagattca
    34981 aacatgggag ggaactggaa agctacaaat cccaaaaaag agcaagaagc catgaaatta
    35041 aagaatacaa aaagtaataa tttattatat gctacgtgta aacattttcg acatgtacga
    35101 gatacagaat ttacgagtta tcatctttca ggaatagtaa ttgacagttt cgtatatgag
    35161 gctatgggaa attggaaatt cgttgaaaat aacagtgggg gtcaaaacat tagttctgta
    35221 tcttatgaga cagctttatt agaatactat aactcacata aagttatggg cggtttaaat
    35281 ttatactctc ctggaagcaa tcaatttgtt aattctgata gtagtatcat atgtttagaa
    35341 aaagtattaa aaaaaatagc tttataaagt tttatggagg aacaacatgg gagacgaaaa
    35401 aaagcgcttg gaagttcaat tacgtgaagc atatggacga gtaacgtata cttacaccac
    35461 tcatttaaag caagccgata atattatttc tgacaataaa attttaaggt gtcttcaaat
    35521 tggtttgtca gcccttacta ctggaggggt acttagtacc attattactg ataatagtga
    35581 gttaaccttt gttgctggat tatgttcaac aatttctctt ggattaaact tatactttaa
    35641 gaactttgat cttgctgaag aagctaaaaa tcatcaaatt gttgccgata aattatggtt
    35701 gatcagagaa gaatacgtaa gcttactaac agatttaaat cgtttaagtg ttgaagatat
    35761 tgtgaaaaaa agagatcaat taatgaacga aactcatgaa gcatataaaa atgcccctaa
    35821 aacaaatagt aaaagctatg aatcagctca gaaagcatta aaatctgaag aagagcaatt
    35881 ttttacagaa gaggaattgg ataagatgtt accagagcat cttagaaaaa agagttctaa
    35941 atattgaact ctttttttat gcttaaaatt ctcttgtaat ttttctattc aatcaataaa
    36001 taatctatat ttaagaagaa atatgatgat agaaacatct cctgaagcca ccgcaagccg
    36061 ttctaagca
//
LOCUS       DACBZK010000020        35882 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.020, whole genome shotgun sequence.
ACCESSION   DACBZK010000020 DACBZK010000000
VERSION     DACBZK010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35882
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.020"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..1152
                     /locus_tag="IVD66_001083"
     CDS             <1..1152
                     /locus_tag="IVD66_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005236379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145320.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSA
                     EAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKED
                     IENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPT
                     RKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALT
                     ATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEI
                     NEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIV
                     NAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            1160..2566
                     /gene="lpdA"
                     /locus_tag="IVD66_001084"
     CDS             1160..2566
                     /gene="lpdA"
                     /locus_tag="IVD66_001084"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HAP6145321.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            2728..3003
                     /locus_tag="IVD66_001085"
     CDS             2728..3003
                     /locus_tag="IVD66_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HAP6145322.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            3009..3776
                     /locus_tag="IVD66_001086"
     CDS             3009..3776
                     /locus_tag="IVD66_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HAP6145323.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            3944..5773
                     /gene="typA"
                     /locus_tag="IVD66_001087"
     CDS             3944..5773
                     /gene="typA"
                     /locus_tag="IVD66_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HAP6145324.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            6034..7806
                     /gene="recQ"
                     /locus_tag="IVD66_001088"
     CDS             6034..7806
                     /gene="recQ"
                     /locus_tag="IVD66_001088"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HAP6145325.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGRNKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            7920..8222
                     /locus_tag="IVD66_001089"
     CDS             7920..8222
                     /locus_tag="IVD66_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HAP6145326.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            8225..9388
                     /locus_tag="IVD66_001090"
     CDS             8225..9388
                     /locus_tag="IVD66_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP6145327.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            9414..12842
                     /locus_tag="IVD66_001091"
     CDS             9414..12842
                     /locus_tag="IVD66_001091"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HAP6145328.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            12863..13987
                     /locus_tag="IVD66_001092"
     CDS             12863..13987
                     /locus_tag="IVD66_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145329.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            13977..14414
                     /locus_tag="IVD66_001093"
     CDS             13977..14414
                     /locus_tag="IVD66_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAP6145330.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            14398..14736
                     /locus_tag="IVD66_001094"
     CDS             14398..14736
                     /locus_tag="IVD66_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HAP6145331.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            14855..15415
                     /gene="rsmD"
                     /locus_tag="IVD66_001095"
     CDS             14855..15415
                     /gene="rsmD"
                     /locus_tag="IVD66_001095"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HAP6145332.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            15412..15903
                     /gene="coaD"
                     /locus_tag="IVD66_001096"
     CDS             15412..15903
                     /gene="coaD"
                     /locus_tag="IVD66_001096"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HAP6145333.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            15893..16936
                     /locus_tag="IVD66_001097"
     CDS             15893..16936
                     /locus_tag="IVD66_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAP6145334.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            17095..17823
                     /locus_tag="IVD66_001098"
     CDS             17095..17823
                     /locus_tag="IVD66_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HAP6145335.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            17939..18184
                     /locus_tag="IVD66_001099"
     CDS             17939..18184
                     /locus_tag="IVD66_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP6145336.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            18181..18399
                     /locus_tag="IVD66_001100"
     CDS             18181..18399
                     /locus_tag="IVD66_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HAP6145337.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            18535..19074
                     /locus_tag="IVD66_001101"
     CDS             18535..19074
                     /locus_tag="IVD66_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HAP6145338.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            19067..21340
                     /locus_tag="IVD66_001102"
     CDS             19067..21340
                     /locus_tag="IVD66_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HAP6145339.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            21378..22424
                     /gene="holA"
                     /locus_tag="IVD66_001103"
     CDS             21378..22424
                     /gene="holA"
                     /locus_tag="IVD66_001103"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HAP6145340.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(22513..22767)
                     /locus_tag="IVD66_001104"
     CDS             complement(22513..22767)
                     /locus_tag="IVD66_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HAP6145341.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(23167..23436)
                     /locus_tag="IVD66_001105"
     CDS             complement(23167..23436)
                     /locus_tag="IVD66_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145342.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(23906..24361)
                     /locus_tag="IVD66_001106"
     CDS             complement(23906..24361)
                     /locus_tag="IVD66_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HAP6145343.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(24499..26427)
                     /locus_tag="IVD66_001107"
     CDS             complement(24499..26427)
                     /locus_tag="IVD66_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAP6145344.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(26624..27457)
                     /locus_tag="IVD66_001108"
     CDS             complement(26624..27457)
                     /locus_tag="IVD66_001108"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAP6145345.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(27649..28353)
                     /locus_tag="IVD66_001109"
     CDS             complement(27649..28353)
                     /locus_tag="IVD66_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP6145346.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(28376..29002)
                     /locus_tag="IVD66_001110"
     CDS             complement(28376..29002)
                     /locus_tag="IVD66_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP6145347.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            29328..31703
                     /locus_tag="IVD66_001111"
     CDS             29328..31703
                     /locus_tag="IVD66_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HAP6145348.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKILYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(31727..32218)
                     /locus_tag="IVD66_001112"
     CDS             complement(31727..32218)
                     /locus_tag="IVD66_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HAP6145349.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            32405..33325
                     /locus_tag="IVD66_001113"
     CDS             32405..33325
                     /locus_tag="IVD66_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP6145350.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            33479..33823
                     /locus_tag="IVD66_001114"
     CDS             33479..33823
                     /locus_tag="IVD66_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HAP6145351.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(34013..34513)
                     /locus_tag="IVD66_001115"
     CDS             complement(34013..34513)
                     /locus_tag="IVD66_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6145352.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            35041..35124
                     /locus_tag="IVD66_001116"
     tRNA            35041..35124
                     /locus_tag="IVD66_001116"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35075..35077,aa:Leu,seq:cag)
     gene            complement(35448..>35882)
                     /locus_tag="IVD66_001117"
     CDS             complement(35448..>35882)
                     /locus_tag="IVD66_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAP6145353.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        11868 a         6262 c         7406 g        10346 t
ORIGIN      
        1 ccgtcacctg tcacagggac agttaaaaac gtgattgttc cagaaggcac tgtagcaaat
       61 gttggggatg tattagtaga aatcgatgct cctggacaca atagtgcacc gtcaactagt
      121 gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat caggttcagc aagtgtcgtt
      181 gaagctgccg atccaaataa acgtgtattg gctatgccat ctgttcgtca atttgcccgt
      241 gaaaaagatg tagatatctc acaagtaact gcaactggaa aaggtggcag agtaacaaaa
      301 gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg caccagcgaa atcagaagcg
      361 ccagaagcgg cagcaccgaa agaagcagct cctgcagcag aaagcaaacc agctgcacca
      421 gcaaaaccat tcaagtccaa cttaggagac ttggaagaac gtgtagcaat gacgccaaca
      481 cgtaaagcta tcgctaaagc aatggtcaac agtaagcata cagctccaca cgtgacattg
      541 catgatgaag tagaagtgtc taaactatgg gataatcgga aacgatttaa agaagttgct
      601 gctgcaaatg gtacgaaact tactttcttg ccatatgtcg tgaaagcttt aacagcgact
      661 gttaagaaat acccagtatt gaatgcatct atcgacgatg caaaccaaga aatcgtttat
      721 aaacattact acaatatcgg tattgcaact gatacggatc acggactata tgtaccaaat
      781 gtgaaagatg cagaccgcaa aggaatgttt gctattgcag acgaaatcaa tgagaaagca
      841 aaattagctc atgacggcaa actatctgca gaagatatgc gcaatggaac aattacgatc
      901 agcaatatcg gatctgtagg tggcggttgg tttacaccag tcatcaacta tccagaagta
      961 gctattttag gtgtaggaac gattgcacaa caaccaatcg taaatgctga aggcgaaatc
     1021 gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc accgtatcgt agatggagca
     1081 actgcgcaac aagcaatgaa taatatcaaa cgtcttttag ctgatccaga gctattaatg
     1141 atggaaggat gataaacaaa tggtagttgg agattttgct gtagaattag atacagttgt
     1201 aattggtgcg ggacctggtg gctatgtagc tgccatccgc gctgctgaaa tgggacaaaa
     1261 agtagcaatc attgaaagag agtatattgg cggtgtttgt ttgaatgtcg gctgtattcc
     1321 ttcaaaagca ctgatagctg caggacacca ttatcaagag tcactagatt ctgaaatgtt
     1381 tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa acacaagaat ggaaagaaaa
     1441 caaagttgtc catacgttga cttctggtgt tggtttccta ttaaaaaaac ataaggttga
     1501 aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca ctacgcgtca ttcatccaga
     1561 ttcagctcaa acttattcgt tcaataacgc aatcatcgca acaggttccc gtccaatcga
     1621 gattccagga tttaaattcg gaggacgtgt gttagattct actggcggat tagcattgaa
     1681 agaagtacct aagaaatttg tgatcatcgg tggcggtgtg attggtgccg aattgggcgg
     1741 agcgtacgca aacttaggag cagaagtaac gattcttgaa ggctcaccac aaattttacc
     1801 aacttacgaa aaagatctag taaaattagt agaagatgat ttcaagaaaa aaggcgtaac
     1861 agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac ggtgacagcg tgacagtgaa
     1921 atatgcagtg gacgggaaag aagaatccgt tactgctgat tatgtgatgg tcactgtagg
     1981 tcgtcgtccg aatacagatg atatgggctt agaacaagcg ggtgtcgaag taggagaacg
     2041 aggattgatc acggtggata aacaaggacg tacgaacgta cctaacatct atgccatcgg
     2101 tgatatcgtt ccaggggcgg cattagcaca caaagccagt tatgaagcaa aaatcgctgc
     2161 tgaagcaatc tctggcaaaa aagtagctgt agattataaa gcaatgccgg cagtagcctt
     2221 cactgatcct gaattggctt ctgtaggtat gacgatcaaa gaagcaaaag atgctggtat
     2281 cgaagcaaaa gcatataaat tcccattttc agggaacggt cgggcattat cgcttggtaa
     2341 aacagaagga ttcatccgtc tagttacgac gatcgaagat aacgtgctta ttggcgcgca
     2401 aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta gctttagcaa tcgaatcagg
     2461 aatgaatgct gaagatatcg ccttgacgat tcatcctcat ccatctcttg gcgaaatcgt
     2521 catggatgct tcggaattag cattaggttt accaatccat atttgatttg aataatacag
     2581 gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta gaattatcaa taatattatt
     2641 atgtaaactt aaaaatatga caacttcttg gtttattacc acttcctatg ctacactgaa
     2701 gaggaatatg aaataggaga gttgaagatg caagaatatc agtatccact tgatttagat
     2761 tggacaacag acgaaatggt cattgtaatg aagatgtggg aagatctgga acgtgcgaat
     2821 gaaaaaggga taaacaatga agcttttttg aagacttatc agcagtttaa aactgttgtc
     2881 aaatccattg gtgaggaaaa acgattggga cgggaatttg aaaaagcttc cggttattct
     2941 ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca aaactttgag aatgaacggg
     3001 tgagataaat ggaacagatg attgatcata tcaagtcctg gcttgaagaa gctggtgaga
     3061 aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa atcaaatcga acggatctag
     3121 taacaaatgt cgatcgaaac atccagaatt ttctaatcga aaaaatccat tcctttgatc
     3181 cagaggcgaa aatattggca gaagaagaag ggtgtaatca attatcggat ctcgatggaa
     3241 gagtctttat catcgatcct attgatggca ccttgaattt tgtgattgaa ggggaaaatt
     3301 tttgtattat gctcgctgtt tatgaatccg gcgttggaaa gcttggtttc atttatgacg
     3361 tgatgagaaa tgaacttttt tggggtggaa aaggaatagg cgtgtataaa aatgatgagc
     3421 cattgcctag accagcaaat aaatccttat cggaaggctt acttggtgtg aatagttatc
     3481 ttttcggtca taataaatat ggaatccgag aaattgcgga aagcagcatg gggacacgta
     3541 tgtacggatg cgctggtctt gaactagtgg caatcttgaa aggaaaccac attgcttata
     3601 tttcaaacct tagcccttgg gattatgcag cgggaaatgt cttattggaa gagtttggta
     3661 tggtaacaag cggtcttttt ggtactcctt tgacatttga aaaaagggaa tactatttag
     3721 cagggacttc ttgtgcatat gcagaaatcg cagacctttt gaaaaaagaa ggctgaaaaa
     3781 aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa agattaattt tctcgaaaaa
     3841 atgaaaacat tttactatat ttcatgaaaa aagtctgcta taattagcag tcgagtaaaa
     3901 tttgccctgt cataaagaac caataaaaaa ggagttagtt acattgaatt atagaaacga
     3961 tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga aaaacaacat tagttgatga
     4021 actattaaaa caatcagata cattagacgc acatacgcaa ttgcaagaac gtgcgatgga
     4081 ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta gccaaaaaca cagctgtaga
     4141 ctataaaggt attcgcgtaa acatcatgga tactccagga cacgcggact tcggtggcga
     4201 agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg gtcgtagatg cgtatgaagg
     4261 aacaatgcct caaacacgtt ttgtattgaa aaaagcactg gaacaacata tcacaccaat
     4321 cgttgtcgta aacaagattg acaaaccttc tgctcgtcct gagcatgtcg tagatgaagt
     4381 tcttgaacta ttcatcgaat taggagcaga tgatgatcag ttagactttc ctgtgattta
     4441 tgcatctgca ctaaatggta cgtcaagctt gtcagatgat ccagcagatc aagaaccaac
     4501 catggcacct atttttgata caattattga aaaaatccct gctcctgtcg ataacagcga
     4561 cgaaccatta caattccaag tttcattact tgactacaac gattatgtag gtcgtatcgg
     4621 aatcggacgt gtatttagag gaacaatcaa agtaggagac caagtagcat taattaaatt
     4681 agacggaaca gttaagaaat tccgtgtaac gaaattattt ggtttctttg gactaaaacg
     4741 tctagagatt caagaagcaa aagctggaga cttgattgct gtctcaggta tggaagatat
     4801 ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat gcgttaccta tccttcacat
     4861 tgacgaacca acattgcaaa tgactttctt agttaataat tcaccatttg ccggtcgaga
     4921 aggtaaattc gtaaccgctc gtaagattga agaacgtttg atggcagaac ttcaaacaga
     4981 tgtatcctta cgagttgaac caacaaactc tccagatgca tggacagttt ctggtcgtgg
     5041 agaattgcat ttgtctatct tgattgaaaa catgcgccgt gagggatacg aattgcaagt
     5101 atctcgtcca gaagttattg aaaaagaaat cgacggtgta aaatgcgaac cgtttgaacg
     5161 cgtgcaaatc gatacaccag aagaatatat gggtagtgtt atcgagtcct tgagcttacg
     5221 taaaggtgaa atgcaagata tggtccatac aggaaacgga caaatccgtt tgacattctt
     5281 aacacctgcc cgcggtttga ttggttattc aactgaattc ctttcaatga cacgtggtta
     5341 cggaatcatg aaccatactt ttgaccaata tctgccaatg cttcctggtc aaattggcgg
     5401 acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa gcaacgactt attctatcat
     5461 gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt acagaagtat atgaaggaat
     5521 gattatcggg gaaaacagcc gtgataatga tttgactgtc aacatcacga aagcaaaaca
     5581 aatgacaaac gtacggtctg ctactaaaga ccaaacatct gtcatcaaaa aaccaaaaca
     5641 attgacgttg gaagaatctt tggaattctt gaatgatgat gaatattgcg aagtaacacc
     5701 agaaagcatt cgcttgagaa aacaaatttt agagaaaaat gctcgtgaaa aagcatctaa
     5761 aaagaaaaaa taatctgtaa aaggatgaag agagaaacca gcttgttata aaaaatagct
     5821 ggtttctttt tttgtccaac tcttttctgt ggagaagtca tctttgtcaa tggacataaa
     5881 ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa aaacttattt ctagagagtt
     5941 tttgtttcat aataagataa tgtttcacga aaggagatca acttgtcctt cgaagaaaat
     6001 cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg acttattaaa acaatacttt
     6061 ggctatgatg agtttagacc tggtcaaaaa gaaattatcc agaaagtcat tgatcaggaa
     6121 aatgtattag gaatcatgcc taccggaagt gggaaatcaa tctgttacca gcttccagct
     6181 ttactattag atgggcttac tgtggttgtg tcccctttaa tctctttgat gaaggatcag
     6241 gtggacgcgg cgaatcaatt aggtataccc gccactttta tcaatagctc gttagatggt
     6301 tacgaaacag ctagacgctt ccaagaaatc gatagacagc agtaccgttt actttatatc
     6361 gctcctgaac gttttatcat gccggatttt atccaagcaa tgaagcgatg gaacgtccgt
     6421 atgatcgcta ttgacgaggc acattgtatc tctcagtggg ggcatgattt ccgcccaagt
     6481 tatttacaga tggcgaacca gctagatcaa ctgccaaatc gtcctgtaat tgttgctttg
     6541 acagctacag cgactgtgca agtagctgct gacataaaaa gacttttaaa aattccagaa
     6601 aacaaccata ttcagactgg ttttgaacga gaaaatctac gatttcaagt aattaaagat
     6661 caaaaaaaag aacaatatct aatcgaatat ttaaagatca acaaaaatca atctggtatc
     6721 atttatgcag caacgagaaa agaagtagac cgtctctatc atttgcttaa aaaattcgat
     6781 ttttccgtgg gtagatatca tggtggtcta aatgagaatg agcgaacaga aatgcaagaa
     6841 gcctttttat acgatcgctt gcagctgatt gtagcgacaa atgcatttgg tatgggtaga
     6901 aataaaagca atgtccgttt tgttatccat tatcaaattc ctggctctct agaagcatac
     6961 tatcaggaag ctggtcgggc gggaagagat ggtctttcca gtgaagccat cctgcttttc
     7021 tctcctcaag atatccaagt ccaaaagttt tttatccagc agtcccaaag agaagaaggg
     7081 caaaagcaaa aagaatatga aaaattaaaa gcgatgacag aatacgtgta tattgagtcc
     7141 tgtcttcagc aatacatcct aaactatttt ggcgagacaa gcagtccgtg caaccgttgt
     7201 ggtaactgtt tagatgacag agaaatagta gaagtaacga cagaagcaca gatggttctt
     7261 tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa tgctgatgaa agtcttagca
     7321 ggatcgaaag aacaaaagct gcaagcttta ggttttggac atttatctac ctatggactg
     7381 atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg aatatttgat atcgaatggc
     7441 tatcttctga ccatcaatgg tgagtatcct gttttgaaag taacagaaag agggatacaa
     7501 gtattgaaag gacaagaatc tgtttatcga aaggaaccca agaaagtcca gcagctatcg
     7561 gatgaagaaa ccgatacact atttgaagtg ctgcgggaac tgcgaacgga tctagcatca
     7621 gaagcaggcg ttcccccgta tgtcgtattt tcagattcca cattgaaaga aatgagccga
     7681 atacgtccat caagcagatt ggagatgctt cagataaaag gagttggcca aagcaagctt
     7741 gataaatatg gcgaagcctt tttatctcgg ataaaaaatg cggactctaa cgttctggat
     7801 aagtagaaag aacgaatacg taaaaatgaa taaaaacaac tggttaaatc tgtttttttt
     7861 gctccttatg aaaatcaaat atgttataat taaggaatta gaatgggagg taagcacaga
     7921 tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa tgatgaagca gaacggatca
     7981 aacgattaat ccgaaatcaa aacaacagtc tctgtatctc acaatgcaaa gccttcgaag
     8041 aagtggtaga tacacagatg tacggctttt cccggcaagt cggttttgct gtccgtatag
     8101 gagtaatcgg aaagaacgag ggccagctga tgttaagtga gctagaacga gaattgaatc
     8161 agttatatag tgaggtttac caagaaattt atgataaaaa agaagttggc aaggaggaat
     8221 agacttgcct aagaaagtga aaaaaaggca tctattagac tatagcatct tgattcccta
     8281 tttaatttta tgtgtattgg gattgatcat ggtatatagt tctacgtcgt atctattatt
     8341 agaaaacgga caaaatccgt ccgcatcagt cattaaccag agtatttttt gggtgcttag
     8401 cttgattgct atcgcactac tttataaaat gaaaacagat gttttgaaaa accagcgttt
     8461 gatcatggca gccatcgcag ttttgacgat tttgctgctg attgttgtgt tttttggtaa
     8521 ggagatcaat ggggcgaaag gttggctgca aattgcagga ttctcgatcc aacctgccga
     8581 atacctaaaa atcatttcta tctggtacct gtctctgact ttatctaaaa gacaaaacag
     8641 tgtacaaaaa gattttcttg ggactgtgaa acgtccactt gcaatggtta tcggacttac
     8701 tgcattagtc gctattcttc ccgattttgg taatgcggca gttatctttt tgattatttt
     8761 ggttctgctt ttagccagcg gagtcaatta tgtgtatact ttgattgtag gagtaggagg
     8821 cttttgtcta agtactttta cgatctggct gatcaatatc acaaacggaa agatcttacc
     8881 cggacgttta cagtatatct ataatcgatt tgctatttac caaaatcctt tctcagacga
     8941 attaaataaa gggcatcaac tagtcaacgg ctactatgcc atgttcaacg gaggactatt
     9001 tggcagggga ttaggtaaca gtatccagaa aaaaggattt ttacaagaag cacaaaccga
     9061 ttttatttat gcaatcgtag tggaagaact gggagtgatt atggggattt tgatattagc
     9121 gttgctattc tttatgattg tgcgcattgt ccttgtaggt atccgttcaa aagatccgtt
     9181 caattcgctt ttgtgcattg ggatcggcgc aatgtttttg atccaagtat ttgtcaatct
     9241 tggaggaatt actggcgtta ttcctttgac agggatcacg ttcccatttt taagtcaagg
     9301 aggctccagt ttgctgatgc tttcgatttg tgtcggcttt gtcctcaaca tcagtgcgga
     9361 tgaaaaacgc aagagcttag gtttataata aaaaaagatg taggagtggt tcgatgaaaa
     9421 aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt atttcgtgct tgtacagaat
     9481 taggaattaa aactgttgga atctatgcag aagaagatga atattccgta caccgtttca
     9541 aagcggatga agcatattta gtaggacaag gaaaaaaacc gattgatgcg tatctagata
     9601 ttgaagggat catttctatc gcgaaagaat gcggagctga cgctattcat ccgggttacg
     9661 gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga agaagaaggc atcatttttg
     9721 ttggacccaa actgcatcat ttagatattt ttggagataa aatcaaagca aaagctgcag
     9781 ctatcgaagc ggggattgct tcgattccag gcacagatgg accaatcgct tctatagacg
     9841 atgccttgga gtttgcgaaa caatacggtt atccgattat gatcaaggca gctctaggcg
     9901 gcggcggacg cggcatgcgt gtagctcacg atgaaaagag tgcaagagag ggctacgaac
     9961 gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga agtgtatgtt gaaaaataca
    10021 tcgctaatcc taagcatatc gaagtacaga ttctcgggga tacgcatgga aacgtcatcc
    10081 atctttttga aagagattgt tctgttcagc gccgtcacca aaaagtagta gaagtagcgc
    10141 cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg ccaggcagct gtccaattga
    10201 tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt tcttgttgaa ggagatgatt
    10261 tttactttat cgaagtcaac cctcgcgtcc aagtggaaca tacgatcaca gaaatgatta
    10321 cagatattga tatcgtaaca acgcaactgt tgattgctca aggtttggat ctgcataaag
    10381 aaatcggatt gcctcagcaa gaaggaatta aattaaatgg ttcagccatt caatgccgaa
    10441 tcactacaga agacccgttg aataactttt taccagacac agggaaaatc gatacgtatc
    10501 gttcacctgg tggttttggc gtacgtctgg atgtcggaaa tgcttacgcg ggctatgtag
    10561 tgacaccgta ttttgattca ttgctagtaa aagtatgtac gcatggtgct acctttgaaa
    10621 cagccattca gaaaatggaa cgttgcttga aagaatttag aatccgtgga gtgaaaacaa
    10681 acattccatt tatgctcaat gtcatcacac atcctgaatt ccaatcagga aatgcaaaaa
    10741 caaccttcat tgatagtaca gcaacattat ttgaatttcc tcgactacga gaccgcggaa
    10801 acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg ttttccaggt atcgaaagtg
    10861 gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga tctaatcaca agaactgatt
    10921 acgtaacggc taagaatgta ttagatgcga agggtgccga tgctttggtc gaatggatca
    10981 aaggacagga aaatttgttg ttgacggata cgacatttag agacgcccat caaagtctgc
    11041 tagcaactcg tgttcggaca aaggatttca agcagattgc acgtttgact ggagaaggtc
    11101 ttcctgaact cttttcaagt gagatgtggg ggggagcaac atttgatgtg gcttaccgct
    11161 ttttgaatga agatccttgg caacggttga gaaaaattcg ttctttaatg cctaatacgt
    11221 tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta ttctaattat cctgacaatg
    11281 tattggtgga atttgtcaaa gaagcagcag cgcaaggaat cgatgtattt cgaatctttg
    11341 atagtttgaa ctggactcca caaatggaaa aaagtatcca agctgtacgg gatactggta
    11401 aaatcgcaga ggcagctatt tgctatactg gcgatatcaa cgatccaagt cgggcaaaat
    11461 acaatgttca gtattataaa gacatggcaa aggaactaga acaactgggt gcgcatatca
    11521 ttgcaatcaa agatatggct gggctgctta aaccgcaggc agcttatcgt ttgattagtg
    11581 aattgaaaga aacgacagat ctgccaatcc atctgcatac tcatgatacc agcgggaatg
    11641 gaatcatcac ttattctgct gcttcaaaag caggagtaga catcgttgac gtggcaatga
    11701 gtgcaatgag tgggaatact agtcagccta gcatgagcag cttgtattat gcactggtca
    11761 atggtccacg gctgccagaa atcacgattg aaaatgcaca gaaattaaac cattattggg
    11821 aagatgtgcg catgtattac aaaccgtttg aaaacggctt gaatgctcct gaaacagaag
    11881 tatatatgca tgaaatgcca ggaggacagt attcgaatct acagcaacag gcaaaagctg
    11941 tcggattagg tcatcgctgg gatgaaatca aacaaatgta tcatactgtc aacttgatgt
    12001 ttggcgatat cgttaaagta actccatcat ctaaagtagt tggagatatg gcactattta
    12061 tggtccaaaa tgatcttaca gaagaagata tttatgaaaa aggcgaaaca ctaagtttcc
    12121 ctgaatctgt tgtgactttc ttccaaggag aactagggca acccgttggc ggatttccta
    12181 aaaaattgca aaagattatt cttaaaggca gacctgcatt gaatgaacgt ccaggtcttt
    12241 tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt ggcagaaaaa attggctatg
    12301 aaccaaaaca agacgaagta ttaagctatt tgatgtatcc gcaagtcttt ttggactatc
    12361 aaaaagcata taatcaattt ggcgatgtta cattactgga cacaccaaca tttttccaag
    12421 gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg cggaaaaacg cttatcattc
    12481 gtttagatga aatcggagaa cccgatatcg aagggaatcg cgtactgttc ttcaatttga
    12541 atggacaaag acgtgaaatc actatcaaag ataattcgat catcagtacg gtccaaaccc
    12601 gattgaaagc tgaaccgaca aaccgagaac aaattggagc aacgatgtct ggttctgttt
    12661 tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg tgatacgttg atgattactg
    12721 aagcgatgaa aatggaaacg gccatcgaag cacgttttga cggagaagtc gcacatgtat
    12781 atgtgtcttc aggagacact atttcgtctg gtgacctttt gattgaagtg actgagaaat
    12841 aataagcgaa aggtggggaa acatgaaaag actgggtttg ttttggctga ttctgctatt
    12901 agttattgtg gcattctaca tggaaccagt cttgtttccg ccaaaacttg aagtgaagga
    12961 aaactctgat caacaaatat caaaccaaat gacaacgtgg aaataccagg agcttaaagc
    13021 aactggtttt tctacttata tcggaaaacc gatcgatcag ctggaaaagg attttggcca
    13081 agcctatgat cgattaacta gcggatttgg ttttgaaaca agatattatg aaaataaagc
    13141 tagtcatctc acatttgaag cgaacatcca agacagcaga gtcacaactg ttaaagtact
    13201 gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg atgacgatgc aagatcttac
    13261 gaaaatcact actatctata ctaatttcac ttttgagtac catgatacag aagttggaat
    13321 cgaactaatg gaagaggata tgaattatcg tccgctaatt gcttttgata acgacacttt
    13381 tgctatttta ttttttgatc aaacaacaaa cggcctattt tcagttgtgt atttagataa
    13441 agatagtctt ttgaaactat tgccatatca agtgtttggt gaaggccttc cacattatca
    13501 agcagataaa tcggctgatt gggaatcaat caatcgcgtt aaagaacgaa aaagtacgac
    13561 tttattaaat atgcttagaa gagaagacga acttcccata tacaatcaaa cacttgcctt
    13621 tcaaaaccac agtcagctgc tactacatga ttttttgaca aggcctgagg aaatattgtc
    13681 agaggaacgt atggctgatt ggcaaaaatc gctaggcagt gctcaaacga cagtgaaatt
    13741 ctcactgacg aatgatgaat tggagaagtt aatcagtaaa caaaaattag aaaatactag
    13801 tgggctattt attcatccgg cgattgacgc tactttttcg tttttatatt ggtacagcga
    13861 tccttacaac catgaccgtt tcatggaccc gggaacggat tctgtaggca ttgctttttc
    13921 taaagaaaat atgttagtct tattgcaaga agaaaacgga gaaagtagtg atagcagtga
    13981 tcgttaacga agagctgttt caactggagg atcaatgcct ccaagtcgct gaaatgataa
    14041 aaaagagtaa aacgatggct tcttatcttg aacataaaca gtcaatggaa gaatctgcaa
    14101 aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga agcatttgaa aatgtagcgg
    14161 catatggtga gtatgcacct gattatcgtg aaaaaaaacg agctgttcga aaagcaaaaa
    14221 gacagcttga tatggatgag catgttgcag ctttccgata tagtgaaaca cagctgcaaa
    14281 gtctgttgga tcaaattgtc caagtacttg ccgaagaagt ttctaatgaa atcaaagtag
    14341 atgcaggtag cccgtttttt gaaacgaaaa aacactttgg atgcggaggt aattgtcatg
    14401 caattagaca atagtgaatt tgaaataaca aaacgacgcg ggctgatcgt atgggtctac
    14461 agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt tgcattatgt ctcaagaaga
    14521 atgaaatatg tcgtgcttta cttaaatgaa gagacattgg aagaaacaga agaacgaatc
    14581 cgtaaattac attttgttcg aaacgtagaa cgttcttacc gaccggatat cgaaatgaat
    14641 tttgccgaaa aaataggaaa caaaacagta ttaaaagacg aaggtttcga aattgaagag
    14701 ctaaatacag aaatccgatt agctgaacat ctttaaaaat ctcttatgag cagtttttaa
    14761 ataaaaaata acttggataa cgatcgattt ttgatcattg tccaagtatt tttttggtat
    14821 actagtacca gtaccatttc taaggagtga gtagatgcgg ataatatcag gaaattatgg
    14881 cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga ccaactacag ataaagtaaa
    14941 agaatccata ttcaatatga ttggaccata ttttgatgga gagacagtat tggatctgtt
    15001 tgcaggaagc ggtggtttag ctatcgaagc agtatctaga ggctgcagtc atgcggtatg
    15061 cgtagacaaa aattaccaag cgctaaaaat catcaaagaa aacatcgaaa ttacgaaaga
    15121 accagagaaa tttaccacaa taaaacttga tgcggacaaa gcaatcgaac ggctagcagc
    15181 ggagaaacaa caattcgact acttgtttct tgatccgcca tatgcaaaac aaaaaataat
    15241 cgatcaaatc cataaaatgg aagaactggg acttttttct aaaaccgcag ttatcgtatg
    15301 cgaaacggat aaaacagtcg aattgccaga aactgtggct ggattccatc aaataagaaa
    15361 acagatttat ggcataacgg ccgtaactat ctatagaaaa gagggaaatc aatgaaacgt
    15421 gcattattcc caggaagttt tgatcctttt acaaaaggtc acttagatac ggtggaacgt
    15481 gcggctaaat tattcgatga ggtagtaatt ggtgttttta tcaatacttc aaagaaaagt
    15541 ttgtttcccc cagaagaaag aatgacattg atcacaaaag ctgtttctca tcttcctaat
    15601 gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa cagcaaaaga gattggtgca
    15661 gatgcgttga tcagaggcat acgaagtatc aaagactttg aatatgaacg agagattgct
    15721 cagatgaatc atcatctata tgatgaattg gaaactgtct tcttattagc aaaaccagaa
    15781 tatagtcacg tgagttccag tattttaaaa gaagtactgc actttggcgg agatgtgagc
    15841 agctacttac cgccagtgat caacgaagct ttagctggaa agcgtgaatc aaatgaaagc
    15901 taaacaatgg ttgaaaacag tactgattat catatttgga atgttgatca ttggatttgt
    15961 agtagttccc ttgccgtatt atgtagaatc accgggagcc acgatcgatc tgaaagaact
    16021 aattacggtc aatgataagg aagataaagg ttctgggtct ttctctctta cctctgttgg
    16081 tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa atgacccctt ttgaagaatt
    16141 gatcagtgaa gaagaattga ctggtggggc gacaaatgaa gaatataatc aaatgcaaca
    16201 gtattatatg gattcttccc aaaatgcagc aatcgaacaa gcgttaaaac ttgcagacaa
    16261 gccttataaa atggaattca aaggcgtata tgtcatgagt gtagagaaaa catcgaattt
    16321 ctttggcaag ctttcagttg gagatacagt aacaaaagta gacgggaaaa gctttcaaag
    16381 tacagaagca tttatggatt atgtaaaaag ccaaaaagtt ggacaaacaa tcgaaatcag
    16441 ttatttgcat aatggtgaag aaaaaacagc ttctggtgat ctgatcgagt taccaacaga
    16501 taaaaaggca ggaataggta tcacgcttac tgaccatacc gagatcgaat cagatacaga
    16561 tgttcgtatt aattctggct ctatcggtgg gccatcagcg ggattgatgt tcactttaga
    16621 aatctatgaa caagtcactg gtaaaaactt gcgacatggt aagcaaattg caggaactgg
    16681 aacgatcaac agtgaaggag aagttggccg aatcggagga atcgataaaa aagtggcaag
    16741 tgcggataaa gctggcgtag agattttctt tgcaccagat gatacgattt cagacgatgt
    16801 taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa gcaaaagctg ccgctaaaaa
    16861 attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta caagaagcgc ttgactatct
    16921 agagaaaatg aaatgaaact aaataattaa agaggggttg tgacacgagt tctgtcacaa
    16981 cccctctttt tcgtcaaaaa tcttcacgat aaaaatgaaa acaaaagaaa aaattgacgt
    17041 aattagatgt tgaagggacg attttgccag agctcactgt ttcttcaatt ttaaatgaaa
    17101 ggagtaatga atgattttta ctggtcattc tttgaaaaaa gaacaatgat agaaaaaatc
    17161 agcaagaaaa tactagcttc acccaaattg atcatttgga tgtctatgat agttcttatc
    17221 ttttgtatcg caagtggttt tttattatca aatttgctat tttatagaga aacagaagag
    17281 actgctgcaa aagaaatact ttcttcgttt agttccagtg gagaagatcc atcagctgaa
    17341 ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt acaccgatat caaaggaagt
    17401 gtgaaggagc ctggtatcta ttccttttct tcagaagaac gggtctatga tgtactaaag
    17461 cgtgcaggtg gattattaga agaagcggat agcgatcgaa tcaacttttc tgcgaagata
    17521 gaagatcagc aagtcctata tatccctgct gtaggtgaag agctgccaga acatcttgat
    17581 cagttggcat cctcggaagg aaaacagcct acagcagatt ccgagcctcc caaaataaat
    17641 atcaatacag ccactccatc agaacttcag cagattcctg ggatcggatc agtcaaagcg
    17701 caagaaatca ttcgatttag agaagaaaac ggatccttcc agaaagtgga agacctgcag
    17761 gagatttctg gtatcggtga aaagacagtt gaaaaactaa aaaacttcgt tacaattaaa
    17821 tagaatgatt caaaatcgac tggcacgagc aataaatgga cgctaatgga tactaagaat
    17881 aatccaattc taagagcttg gcaggacgag gaggtagtat ttttggatag gaaatagctt
    17941 gattgttcgc aaagaaacat taaaaaaacc aatgctgaat gtctatctcc aaaataaaat
    18001 atctgggatt catattatga atacggctgt cagcggcaat aacagtcaag ctctacgaga
    18061 acgctttgcc aaagatgtac ttagctatac agcagataaa gtatttattc tcattgggac
    18121 gaatgatcta gcagagcata aacaactttc taaagaaacg taccaaaaaa tctgcagtgg
    18181 atgatagttc agctgaaaaa agactatagt tctgatcatg ctttctttat cacgccacca
    18241 gcagtcgatg agacaaaaca aaaatatcgg aataacaagt tgatcaaaga atatatctct
    18301 gttctcacag aagtagcaaa acgccatgat tgtgaagtat cgatttttat acggaatttc
    18361 ttgaacaaat ggattcgaag aatttttata atgggctaat ggatgacgga cttcatttcg
    18421 gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg ttatatttaa agaatatttt
    18481 gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg gaggaatata aaacatgtta
    18541 gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag ttactgataa gtcacataat
    18601 gaacgcattc cttgggacca gtactttatg gctcaggcag tactgttatc tttacgtagt
    18661 acgtgtacac gtttagaagt aggagcgaca ctcgttcgag aaaaaaggat cattgctggc
    18721 ggctataatg gagcagtcag tggagatgtc cactgcatag atgaagggtg ttacgtcgtg
    18781 gatggacact gcttgcgaac gatccatgca gagatgaatg cactcctaca gtgtgcaaaa
    18841 cttggtatcc cgacggaagg ttcagaaatc tatgtcacac attttccatg tttggcctgt
    18901 acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt atctccatga ctatcgaaat
    18961 gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat ctgtacacca agttgcttta
    19021 gactcacagc atttttcaaa acttcaaaat gaattaacag gaaaacatgt ctagcgtttt
    19081 agaaaggcat gttcgaaatc ggttgatttt tccggcaatt acgtcgatga ttatctgttt
    19141 gttgtattac actgacaatt ggggttatcg tttgcttctt gccggaattt ttttatggtt
    19201 ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt ttgtgtagca taacggtatc
    19261 catttcttat aggctacaag agtattcatt tttagaggaa aaaacaacat ctgcgcaaat
    19321 tactgtattt acagatacga ttcgtgcaaa tggtaatttt ttgacaatgg aaggaaggtt
    19381 atcagagaat aaacaaaagc tccagctttc ttatcaagta aacacagaag cagaattgaa
    19441 aacatggctt aacttccgag gaaagggaat agaattgact gctgaaggcg agttcatctc
    19501 tccagcaaaa aagcggaatc tttataattt tgaccaagaa gcttacttca ggaaccatag
    19561 aatttctgga cggttccaaa ttcaaaagat tgaacagatc accatgcaaa atcactggcg
    19621 aaactggctt cagagaaaaa gaggatcttt tatctccttt gtccaatctg aatttccgca
    19681 aaaaacaagt gtatatatta attctttatt atggggctat aaagatgcag gattcagaga
    19741 accagaagaa atttttaggg agagtggttt gctgcatctg ttcagtctat cgggtctaca
    19801 catccaattt tatttagggt ggctgtatta tttatttcga cgtatcggat ggccactaca
    19861 cgtcagtatt attccgttga gtctactaac tatctgttat gtttctattg caggaagttc
    19921 tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga ttgctagtca aattgctgaa
    19981 taagcattat tccaccatgg acttatttgc agttgtcttt tggcttcttt tactatttga
    20041 tcctcgattt ctttttcatg cgggtggaca gcttagtttt ttcatgagtt ttttgtttat
    20101 cctgatttct tttgatggag attggttgaa aaaaacggcc tctcacgtcc tgtttactat
    20161 gatcacgatg ccgttgattg tatggcattt ttatgagtgg cctattttag gtagtctttt
    20221 tacattactg attgcaccgg tattcaagtt tctttttctt cctggtgtgt tatttctcac
    20281 actcttcaat cgctggctgc cggaaacttt acttttgttg atagaagagg gattaatctt
    20341 atttgagcga ataatcgatt tttcttcagg gtcgtctctc attataggac gtttgcccct
    20401 tgtgctatct gggatgtata ttttcggatt actgatttgt atggataggt tgaaagaaca
    20461 acctgtgaaa cacttgtttt atgttggtct tttttctttt atttttttga ctttgccatt
    20521 tttacgcttt tcttcaacga tcgcttttat cgatgtcggt caaggagaca gtatcttttt
    20581 gcaaagtcct tttcgaaaag aaacgatttt gatcgatact ggaggtcagt tacactttga
    20641 aagagaaaag tgggcgcaag gtatgatacg tcctcctgct gaaagaaata tcgttccata
    20701 tctaaaaggt caggggataa gtgtaatcga taaactcatc ttgacacacg acgatacgga
    20761 tcatgtggga gaattaccca cgttatctca gcattttact atcaaaaaaa tttatatcgg
    20821 ttggggcgct ggacgaaatg agccattaca aaggcattta tctgaagctc aaaaaaatgg
    20881 tactgagatc attgaaatca aacatgggga caggatcagc ggttattatg atctttatgt
    20941 attgactcct tttgaaaagg gagagggaag aaatgaagat tcgattggtc tatggatgga
    21001 atataacaat aggcgctttt tatttttagg agatttgaat caagcaatgg aaaaacaatt
    21061 gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa ttaggtcatc acggtagccg
    21121 tacgtcaagt aacacagatt ttctttccca tattgaagca aaacatggga ttatatcctg
    21181 cggcgtaaat aatcgttatg gtcacccgca cagcgaagta ttggagacac tagaagaaaa
    21241 tcagataaaa acatggcgaa cggatcaaca aggaatgatc acctatcgct ggcatccagt
    21301 ttttcatcct catgggctag tggaaacaat gatagactag taattctcat ctgctcatgg
    21361 taggataatt tttgaaagtg gtgagtaatt tgagtataca agcagagtta caaaaaatac
    21421 gtaaagaaaa acttgcatct tgttacttga ttttaggaac agaaaagttt ctccaagatc
    21481 aagttcggac agaaattgtc aaaaaaatcc aattagaggg cgaagatgac ttaaattttt
    21541 taagttttga catggaaaat gcaagtttag atgaggtagt agctgaagca gagacgttgc
    21601 cgtttttcgg agatcaacgg ttagtattcg tagagaatcc ttatttttta acaggtgaaa
    21661 aagtaaacaa tggaatcgaa caaaatactg atttattgac ggcttatttg aaagaaccat
    21721 tagaatcgac tgtattagta ttctttgcgc catatgaaaa gttggatgaa cggaaaaaag
    21781 taacgaaaca attgaaaaaa acagcaatta tcatcaatgt ccaacagttg aatgaaaaag
    21841 aagtacgtca atatctgatg aataccttag agaattcctc aatcaaaatg gaacgaagtg
    21901 caattgattt attcttgagg ttgaccgact tagatttatc caaaatgatg agagagttac
    21961 agaaattggt cctttatgga caaaatcaac agcaaatcac ggtaagagaa gtagaagaat
    22021 tagttcctaa aacgttagaa cataatattt ttgacatgac ccaatatatt ttaaaaggga
    22081 agacggaaca agctttgcgt ttatacgaag atttagttat gcaaggggaa gaaacaatca
    22141 aaattaatgc gattttgctt tctcaattac gtttattttt acagacaaaa tttcttgtaa
    22201 agattggtta tcagcaggca aatattgctg aaacattgaa aatccatcca tatcgtgtaa
    22261 aacttgccat gcaggaagta aaaaaattcg atgaacattt gctggtacag ttgtttgatc
    22321 aattagttga gatggattat caaatcaaaa cgggacaaat cgaaaaagaa ttaagttttc
    22381 aactattcgt tttgcgcaca gggcagttgt taagaaatcg ataagaagaa agacgagggc
    22441 aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg acaaataaaa aaatcggccg
    22501 aagccgattc ttttatttag cgattttttt gcttaaacga gatttgtcgc ggttagcttt
    22561 gtttttgtgg attagacctt ttgattcagc catatcaata gctttaacag cttctttata
    22621 taacgcatct acgttgtcag cacctgaagc tacagcatct tcaaattttt tgattgcagt
    22681 acgcatagcg cttgtttgag atgaattttt cacattagcg ttttcgcttg tacgaacacg
    22741 tttgattgca gattcaatgt ttggcattag tttcacctcc gataacttaa gttcttacgc
    22801 gtgttaccgc ataattcaac attcattatt atacctaaag gcagcgtgct ttgcaatatg
    22861 aacatgacaa gtttttttcc ttaacagtct tttattagga ttttttttca gtaaaaacgg
    22921 atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg gaggcaatag cgtcaaacca
    22981 aactagattt ttatttatct atttaaacaa agtttgaatg ggaatgtttg gtactaagtt
    23041 attatataac aaagagaacc gtttgcaaag ttttttttga aaagggatac gattccctgt
    23101 tgttctttgt ttttctatta agaaactgca gttattttat aaccagtatc ctttgatcag
    23161 taaaggctat tctggtgtac cgattatttt aatgtattca tcgatatttt ttatcaacat
    23221 tttttttatg accaactggt tccgacggtt ccatttgcca cttacttcca gcacatattt
    23281 atttaggggc aaacgtaaga tatattttgc caaatagcga tctttaagca ggccattgat
    23341 cacacggtcc tcaagctgca agttgatccc agtcagcatc attggctgtt cttgtaaaac
    23401 gtacgtatca attaaaagac cttcaaaagt ttccacaagc gtcttccttt cttttcaaag
    23461 taacctgaaa acaggcacta attcttccat tttgatattc gttgaagtgg atgcgatcat
    23521 tctttctttt gtccactgta atctagtata acaaaaaaga gcagaagagc caaaaagaaa
    23581 aaagagcatc gaattctata ggaagtctca ttggcacggc ctaaattatt acaaaacatt
    23641 gattaaaaaa agcccctgca tcgcaggagc atcccctata tcgttttaat aggtcaatca
    23701 aaaagcagta tcaaacacat tttgtatcaa atcaggaaat aatagataag ctaagcccag
    23761 aatcaaaagt accgctagaa gaaaccagcc gattgttcct atgaaatact ttaatttttc
    23821 gaacattgta tcacctcgtt gtcagtatat cacggatcag taaattgggg gtgttaagaa
    23881 tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc aaatacttgt aagatacagt
    23941 aagtgatacc agaagcaatg accggtccgg cggcgattcc tcttaagaag acaacaccta
    24001 aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc agaagcaatc aatcctacac
    24061 ccttggaaga taagacagcc actagcccac cgcaaaaaac agctacccag ccaatagggg
    24121 atttaaaggc ttctaataga tcacgtagac cgatttctcc tgttgcgata gggattagaa
    24181 tagccgctgt gatgatcgtc accccaatat tgattccttt gccttgaagc caagggaaaa
    24241 aggaacggga ggctggtatg agcttcataa tcaaaacaaa agctgccgct atcatcagac
    24301 tttgattttt agctaaaatt gctacaagta aaataattcc taaaaaaagc caactttcca
    24361 tgaaatatat tcctcacttt cttcgaaaca atcataacat gtttttagaa agttacaaaa
    24421 gtaggaattc atccttcaag acctattcat aagctgtttt tttcataaaa taaacaaaat
    24481 cataaaaaaa cactttgctt atttgacaga agacagccgc gctttgtata gtggacaaga
    24541 cttacatttt tttgaagaat cagaaagatc aggtaaaggt cttagtaaac gcaagccatt
    24601 cagaataacc aatattgtgc ttccttcgtg tcctacaact ccaagaggta gatttaaaaa
    24661 ttgcaggaag ttagaagcaa tcaacaagag aataacaaga atcgaaaaaa taatattttg
    24721 tttgatgatc cgccgcattt ttaaagatag ccgatgactg tagacaaatt tatttaagtc
    24781 gcttttcatt aagacgatgt ctgcgatatc catagcggca tctgtccctt gccccatagc
    24841 gacacctaaa gaagcggctg ctaaagcagg cgcatcattg actccatcac caaccatcgc
    24901 atttacttgg taaagttcat tctctttttt gactagttgt gttttttctt ccggagtaca
    24961 gcttgcatag taatgttcaa tccctacttg ttcagcaatg gcctttgctg tgccagaatg
    25021 gtcgccggtt atcatacttg tatggatgtt ttgggattta aagtaggaaa ttacttgttg
    25081 ggtatttgct tttggaatat ctagcagacc taaaacagca attaactgct gatctttaga
    25141 aagataaatc acggttttgc cttgattttc caaacgttcg atcatttccg caatctcttt
    25201 gctgattatc atcgtctcag gatcatatgc gtgcttgcca actttccatt gcgcacctaa
    25261 ataggtagtt tgtaatccaa aaccagtaat ttcttctatt ggtaagtatt ggatttcttc
    25321 aggtattgtg caatcgaaat attgcaaaat cgcatgagca agtggatgcg tcgttttttg
    25381 ttccatagca acaagaagtt gttgtgccaa atccttttca tcaaagaaaa agctgtcagt
    25441 tacaactggt tttcctttag tgagcgttcc tgttttatca aaggcaatcg cttttaattc
    25501 agaaagcttt tctaaatgga taccgccttt gattaaaatc ccattttttg cagaatttga
    25561 aagagcagct agagaagctg gtgtagcaga tgcgacaagc gcacaaggag aagccacaac
    25621 taataatacc attcctcgat aaaagctttc atcccaactc caacctagga aaaagtgggg
    25681 gagaaggatc attagaggaa cagcaagcaa aatcaatttt acataattat tttcgattcg
    25741 ttcgataaat gaagctgttt gagttggcgt attctgcgct tcttctacta attggataat
    25801 cttagcaaag acagtttcgg aactcgtttt tgttactcga atcgtgatgg gatttccttg
    25861 attcagcgtt cctgcataca tctcatcgcc taaatatttt tctacaggca cagattcacc
    25921 gcttaatgca gactcatcga tcgttgcctg tgtgctttct aaaaagccat ctatcggaac
    25981 agctgctcct ttagcgacaa ataccaagtt atccaccttt agttgagaaa catctacttc
    26041 ttgcatttgt ccattttctt ttaataattg ggctttttgt ggttgaagat tcatcaaagc
    26101 agtaatttct ttttgacttt tattagttgt gtattcctct aatgcaccgc ttaaacaaaa
    26161 gatgaatgtc aacattgctc cttcaaagta attaccgatc aaacaggcac caatagcagc
    26221 taaagccatc aataaatcca cattcagtgt ccgatcattc cacaattctt tcaagccttc
    26281 cgatgtttgt ttatatccac cgatgataat ggcactgata taaaaaagtg gggtgatggt
    26341 aagagagaat cggtcgaaga taaaaccgaa gatcataaat aaaaggcagc cgattgttgc
    26401 tgcaaaagct tttttctgat tagtcatcgt tattagacct ccttgtcaaa acaaggatag
    26461 cataataaaa atgtaattga taataataac agctaaatga gaacgataat ggttatcatt
    26521 tggtgattaa gcttgatgtt gtttttatta tttataatga ttattattaa agaaaataaa
    26581 aaaccagaac atttctcaaa taagagaagt gttctggttt tttctacatt gcaataaacc
    26641 aataaccaat caaaatgata ccaaggataa tacgatacca gccaaaagcg gtaaagtcgt
    26701 ttttcttcaa atagcttagt aagaatttga tagctaagac ggaaaccaca aaagatacga
    26761 atgttcctac aagaagaaca acagtttctt ccattttgaa tgaattccct tcagctaaat
    26821 atttgacgat cttcaagccg cttgcgccaa acatgacagg aatccctaag aaaaatgaaa
    26881 actctgtagc gacaaaacgc gaagcaccaa tcaagataga tcctaggatc gttgcgccag
    26941 aacgggatgt tccgggaaca agtgccaaga cttggaataa cccaacaaga agagctgctt
    27001 ggtacgtaaa gtcattcaga gaagtccaac gaggtgtttt gtttttgttg cgtttttcga
    27061 caataataaa ggcaataccg taaacgatca aaacaatggc aactggtaag aacttgtgga
    27121 aatttgcttc taaccaatca tccaaaggca aaccaatgat gatggctggt atgcaagcaa
    27181 cgatcacttt aaaccaaagt gtccacgtat cttttttttc taccgttgat ttacttggag
    27241 aaaatgggtt taacttgtga aaataaagaa cgacgacagc caagatcgcc cctaattgga
    27301 taacgacatt gaacatcgac ataaattgtg aactggcatc cagtttgatg aattcatctg
    27361 ctaggatcaa atgaccagta ctactgatgg gcagccattc cgttattcct tcaataatac
    27421 cgagaatcac tgctttgata atatttgcaa aaaacataaa ttccttcctt cccaattaag
    27481 atacatctta tagtataccg ttattttttg agaaacccaa tctgtttttt aatattaaga
    27541 aaaacttgag aaataaagca gataagtaca cgaagagaaa aaagaagaca aagccctcgt
    27601 tcagactttg ccttttatga ttctctggta aaaattaaaa tatccccatt atagaaacga
    27661 gtcgcgacta tgtgttttcc cgttatcgat ataagacgta tcattgatgc cgtggataga
    27721 aaatcgaccg tttgcataag tgacctttgt tacgctgcca tttaaaagcc cagcacgaac
    27781 aggctgttta ggatcgatca gattaagcaa aaaggcgatc gtcaaaccat gagatacgac
    27841 taaaacattt ccaccaccat ttttttcgca gtgatgggcg atatcttcaa atcctgtcca
    27901 tacacggtct cgcaatgttt cataagtttc cgcccaccca gcggtatcta agttgtatac
    27961 agcattagca atttgttcaa aagaaacttc tgtggtaaac atttcatcat atgttttaaa
    28021 attcaataca cgagggatca caccccacat ttccatgtca tatccacctt caagagaccc
    28081 gaaacaccat tctctaatcc ttttttcaat aaaataagga atttcttttc ccttagaatg
    28141 ttctcctaga ataatacggg cagtttcgat tgcacgacca ctgtcactag aataagcaaa
    28201 tgaaaagtcg acatttttta acccgcgacc taaataatga atgccttctt gtccttgctt
    28261 tgtgaggggt gtatcacacc agccttgtac tcgttcaatt gtattgaaca tcgtttttcc
    28321 gtgtcgtacg atataaagtg tagtttctgt cattttattc tcctcctaag tcgttttaac
    28381 gattgaaaaa aggatttgtc cttttttcct gttcaatcgt cgttgcatcg ccatgtcctg
    28441 gatagactgc aaattcatca ggtaatacaa acagctgggt ccgaatacta tgaagtaatt
    28501 gttctaaatt ccctgtatac agatcggttc taccgatact tcctctaaac agggcgtcgc
    28561 cagaaacgac aaaatcatca aaaataaagc tgacgcttcc tatagaatgc cctggggtag
    28621 ggacgacgcg aaaagacatg tttcctaaag tataagtttt catttcaaat tcatattctg
    28681 caggcgagac aataacatca gcaatatcat catgtctacc gagtccagaa agattcaaaa
    28741 tcggatcacc tagccatttt tgctctagtg ggctgacata aactgggatt tgataatacg
    28801 cgcgtaaagg ttccactgca ccgatatgat cgtagtgagt atgggtaagc aaaatcgcta
    28861 ccggctgttg gtttgttttt ttgatttctt gtttgattcg ttccgcatct tctccagggt
    28921 caatgatcaa aagtgcttct tcgttgtaga ccaaataaca gttttcttca atcattcctg
    28981 tttttaatct ttcgatatgc atgtgcattc ctccttgata gccaaaactt ctttcatcca
    29041 ttagtataac gcattcattg ctaggaaaca aaaacaggta cttatttctc tttacttatc
    29101 tgaattatca gactatatga aaagtatttg gatattctaa agagaaggaa agtaagtttt
    29161 catagcattt taatatgtcc ttgttacatt agattcatcc aaaaatccaa attctatatc
    29221 ctatatccct gcctaatcag cagggtgttt ttttatgttt ggaaagagag ctctttttgc
    29281 taaactaggt tttttcaggt aatcttagag agaaagaggt ggtggaaatg atcaaacagt
    29341 caaaaatatc tgtgcggcac ttagtagaat ttattttgcg acgtggaagt atcgacaatc
    29401 gtaaaaaaag taaccatact gcattagaag gagcgagaat ccaccgcaag ctccaaaaag
    29461 atgcgggaga aaactatgaa aaagaagtct ttttaaaaac aacagttcaa ttagatgaat
    29521 attacctgat cgttgaaggc cgtgcagacg gtattttcaa aagagacggt atttattata
    29581 tagatgaaat caaaacctcc gaaccacgat ttgaagattt agaaccagaa caagtggaac
    29641 ttttctttca tcaagcaagg gtgtatgcct atatctatag tcaagaacat gatttacaag
    29701 aaataaatct gcaattgact tacttccaga cggcagaaga agtgatcacg agaaaggttg
    29761 aacatcagac aagagagcag ttagaaactt tttttaaaaa gctgactgaa gattataaag
    29821 aatggcttgt ttttcaagaa aactggcgca ctgtacgcaa tgcctctttg atggctttga
    29881 aattccccca tgatgagtat aggaaaggtc agcgtgaact agcggtagct gcttataaaa
    29941 cgatccgtac gaaacagaaa ttgtttgtag aagcacctac cggaacagga aaaacaatct
    30001 ctacgttatt ccccgctttg aaagctgtag gggaagaaga gggagaaaag atcctttatc
    30061 taacggctaa aacaataact agacaagtag ctgaagatgc tatgacagca ttaaaagata
    30121 caggagctga agtaaaaagt gtcactttga cggcgaaaga caagatctgc tttttagatg
    30181 agacgacctg taatccagat cagtgcccat atgccaatgg ttattacaat cggattaatg
    30241 aaggtttatg ggatcttttg aatcatgaga atcagatcac tcgtgaagtc atcgaaactt
    30301 atgcaagaaa gcatacactt tgtcctttcg aactatcatt agatgtcagt atctggtgtg
    30361 acgtaatcat tggggattac aattatttat ttgatccaac tgtttattta agacgttttt
    30421 ttgaagatga aaaaaacgag gactatctgt ttttgattga cgaagcacat aatttggtga
    30481 atcgttcccg agagatgtat tcggcagaac tatcttatga aaaaacgaaa cgaagtaagg
    30541 aagctatacc aaaggaattc aaaaaacttc atcgccgttt caacaaacta ttaaaagaat
    30601 ttgattcgat ccgagaaata gcaaaagaag atcattggga ttatcatcat caaaaagcac
    30661 cggctgaatc tttagtaaag gcaggttatc aattaagcga aaaaattaaa gaatggctgg
    30721 cagaatttcc tgagcaccca tcacaagaac aattgcttcc ttattatttt gatttgcttc
    30781 attttttgaa ggtcagtgaa ttttatgatg atcactacga aacaacagtc gaaaaaacgt
    30841 atcgcgatct gatagtaaaa gagttttgta ttgatccaag cttgtttctt gagcagtcgt
    30901 tggataaagg aaaaagcagt attctttttt ctgctagttt ttcaccactc tcttattatc
    30961 aggaaacact ggggggacaa aaaagtctgg cttacaaact gccgagtcct ttcccagaag
    31021 gaaaccagca agttttcatc gcaaattacc tagagacgac ttatcgaaaa agggaacaca
    31081 gtctggcaaa attagtagag acgattcatg cttttgctga tggaaaggtc gggaattatt
    31141 tcgttttctt tccttcttat caatatttag atcttgcggt ggaagcattc agacagcaat
    31201 atcccgacag caatgtgcta atccaagaaa cggacatgaa tgaggaagaa cgcgaacgat
    31261 ttttaacaaa atttcaaaca aatcccgctg aaacattgat tggattttgc gtacttggcg
    31321 ggattttttc agaaggaatc gatttgagag gggaccgatt gatcggcagt atgatcgtag
    31381 gtgtaggttt gccgcagatg aatcatgagc aggaactgat caaatcatat tatgatgaga
    31441 aggaacacct tggatttgct tacgcttatc agcttcctgg aatgaacaaa gtcttgcaag
    31501 ctggtggtcg agtgattcgt ggcatggcgg atcaaggaat cgttgtattg gcagatcaac
    31561 gattttctag tttttcttat cgacgtttat tcccacaaca ttggcaaaca gcaagagaag
    31621 tacgaagtgt tggggaattg gaagaaggaa tacagcgttt ttggttatca aaagaagcag
    31681 taaatcaaaa aaacgaggaa tgacagacgt cagcctcgtt ttttgattaa cgatagttag
    31741 tgaattgcaa ctcgattggt aagtcaagtt tacgtaataa agcaatcaca gcttgtagat
    31801 catcacggtt cttacctgtc actctaatct gatcttcttg gatttgtgct tttactttca
    31861 gtttttcatt tttgatagct gtagtgattt tcttcgcgtt ttcacgatcg attccgttga
    31921 ccaaatcggc agtttgtcga gctttgccac ctagagcgtg ttctgattcg gaaaaatgga
    31981 tatttttgat tggcacattt cttttgatca gcttaccaaa taatacatct ttgatctgtt
    32041 cgattttgaa atcatcatcg ctcaatacaa ctagattgct gttctctaat ttgatttcta
    32101 ctgtagaatc cttgaagtca aagcgattgg acaattcttt tgttgtttgc tgaatcgcat
    32161 tttttacttc ttctgtattg acttctgata caatgtcgaa gctagcatct tttgccatag
    32221 gaaccctcct gatatacata taaatattta ccatacatct atcttatcat aggattaggg
    32281 cagattctta cctgtttgct aaaattcttc tcatttgagt tcgaagtatt ttattttaat
    32341 agataaactg ttattcttac atttggaata ccaaagtagg ggagaggtgc ttgtgagtaa
    32401 aattatgact gcgtatcata aaaatgaaag attaaagaaa atagtggtta ttttgataac
    32461 cggattgacc gctgcggtcg ctttaaatta ttttttgatt ccagccaatg tcttttctgc
    32521 agggatgaat gggatcgctc aaatcatttc ctcgctttta tatgaatggt ttcatatcaa
    32581 gatagacaca ggaacattta tttttctttt gaatatccct gtgtttgtat tagggtttct
    32641 caaagtagga aaacgagcaa cgatccttag ttttgtgaat gttgtatgtg tatcggtgat
    32701 gacgatgctg cttccagtcg gacagatcac tgataatatt ttgatgaatg ccctagtagg
    32761 cggtgtttta ttaggtcttg gcgtaggatt atctttaaaa atgggcttta caactggtgg
    32821 gatggatatc atctctcttg tactttcaca aacaactgga aaaacagtcg gaaactacat
    32881 gctgattcta aatggtatca ttgtagtcat cgcaggcttc ttctttaact gggaaagtgc
    32941 cttgtatacg attatttcca tttatgcaat gactcaagta attgatgcca tccacacgag
    33001 tcatcaaaaa gtaacagcaa tgatcgttac cgtcaagcca gaagaggtaa cagaagaact
    33061 agcaaaacgg atggtacgtg gaatgacatt actgccgtct gtcggtggct attcaaaaaa
    33121 acaagggaac atgatcatga tggtcatcac ccgctacgaa atgtatgatc ttgatcagat
    33181 cgttcatgaa atcgacgacg atgcatttat caatatttta ccaactcatt cagtatttgg
    33241 ccggtttgca aatgaaaacg aacaaaaaat gtatcgaaca actggcgtat tgccagaaat
    33301 aaaaaatcgt tcacaaaaaa aatgaggaat caggtttatt ttagaataaa tttaatctat
    33361 tacatctaat aagaacattt ttataaattt aaacgagaat cttacttcta aattctcatt
    33421 tacaagcagc taaaaaaaga gtatgataaa taaaaatcgt gttaaggagt gtcgtacgat
    33481 gagcgaagca aaccaagaac ggtctggaca agaaatagaa ctaatcaaag aacgtattct
    33541 tgctgccttg gaaatggtga ttgatcctga attaggaatc gacatcgtca atttaggctt
    33601 gatttatgat atagaattca atcctgaaaa tggagaaaca gtcattaaga tgactctaac
    33661 aactatgggc tgtccattag cagatatttt aacagaatct atccatgacg cattaaaaga
    33721 agtgccagaa gtaacgaaag cagaagtcaa actagtctgg tatccagcat ggacgacaga
    33781 taagatgagc cgttatgcac ggattgcgtt ggggatacga tagaaatctt ggctgactag
    33841 ctatgagaag caaataggaa aaacaaaaaa gccttttatc ctttctagaa gaaaagagat
    33901 aaaaggtttc tttgtttata aaattttgtc tgctatatta taagttaatt aaataaatgt
    33961 gttctattga taaaggacat tcaaatccct ttccttttgg aatccttctt ttttacatca
    34021 gtttgatttt cgtatagtat tctttctcat cttcacgata aatcgcagcc ccattttttt
    34081 gttgtgcttt aagactgcca agattttttt tatttacaga caaaagtgcc tcatcaatgc
    34141 cgattttttt tgcctcttgt agtactaatg ctaatccttg tgtggcatat ccttttttac
    34201 gataattagg ggagatgccg taaccaatat ggccagcgcc gtttcttaat gtttcgttca
    34261 gtttatggcg caaattaaaa attcctacat actcatgttc atcactttct aaaataaaga
    34321 cggttgcggg aacgtaactc tcaggaagat cgattcctaa agacgttttt tcgcattttt
    34381 ttacataatc taaaaattca gcaaatgtat agccataagc attgttgata aatccactct
    34441 catttggtcc aaagctagtt tgtagctgat aagctttctt taaatctgct tcccatagtt
    34501 tgatcagttt catcgtattc acctctttaa gtaaccttat tcatttgttt tctactatag
    34561 cactattgtt gtaaatagcc atgcctattt ttatttattg tgtcatatcg tattaagaat
    34621 catcgaacaa tacaaatatg aattacaata aaaaaattat ttgaagttcg ttcattcgtt
    34681 acttatgatc tctagaagaa agaaaacgtg aattacttca gcgtctagaa ttccagaagg
    34741 atagtaatca acagaagaaa taatcaatat ccaaatgaaa gaagatagct gaatcgagaa
    34801 aaagaggaaa aaagaaatga agaaaaaaat aaaatagtta ctaatcccag agtcgttcgt
    34861 ttaacattga aatcgatcat atggataaaa cagatttttt caccaaccct caatagatga
    34921 tggagttgct cggatgaatt atttgtgtag atggcataag ggagggcgta cagaaatgaa
    34981 aaagaacaaa aatatgttct tgacaaaaaa cacatgtaat cctaaactaa aagatgtgat
    35041 gcggctatgg cggaattggc agacgcgcta gcttcaggcg ctagtgaggg tgacctcgtg
    35101 gaagttcgag tcttcttagc cgcataattt gtttttttat aaagagaagg tacacctgga
    35161 gcgatgagaa agaaaataac atattatcta aaagaatata ggaaaaattt taaacaacgg
    35221 aaccagattc aaataaatca aaaaaaattt gtgtgaaggt gggacagttt aaaacctaat
    35281 agattgattc aaatagtaga tttatagatt ctgatacaag aaatactggc aaacgatagt
    35341 taaggaataa agactaaact taaactcaaa aagaggtcat gcgaaagaat aaatcgcatg
    35401 acctcttact atattttgaa tgtgtttaaa cgttcaaata atgaatctta gtaccaaccg
    35461 tttgcttccc agaatgcttt cgccgcttcc caagaaccat aacgtgaagt aacatattgt
    35521 tctgctactc tttcttggtt tgcagcagag tagtcaccat ttaagtaaga agaatctaat
    35581 tggtaacggc cgatgtaacg tccgttcgtt gctgtgtaag aaccgcttga ttctttttgt
    35641 gcgatccatt cttttgcaga gcttgtactt gctggagtag cagcagtttc tgttacagca
    35701 ggagcaggtt gtgtttcagc aacaggcgct gcttgtgttt ccgtttgaac cgtttcttgt
    35761 acaacaggtt gttcagcttg aacaggttca gcttggactg gtgcttcttg aacggctgct
    35821 tgaggttcag cagctgcttg tgcagagcct tctgttggga ttgttaattg ttgtcctgag
    35881 ta
//
LOCUS       DACBZK010000021        35719 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.021, whole genome shotgun sequence.
ACCESSION   DACBZK010000021 DACBZK010000000
VERSION     DACBZK010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.021"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..705)
                     /locus_tag="IVD66_001118"
     CDS             complement(<1..705)
                     /locus_tag="IVD66_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAP6145354.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFI"
     gene            1393..1551
                     /locus_tag="IVD66_001119"
     CDS             1393..1551
                     /locus_tag="IVD66_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6145355.1"
                     /translation="MNKKQTCEFLGIDNNTLDKWIRIYNFPVIRIDGIVRFDIEDIKD
                     FMNTFKTI"
     gene            1623..2849
                     /locus_tag="IVD66_001120"
     CDS             1623..2849
                     /locus_tag="IVD66_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6145356.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGITSEKYQKVFPTRQLAIKA
                     ENAMKRKIETVLREENANSLELKGKIKFKEFYESKWLPRYELGQTTRSKRAPSYVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQCITAPKKIALEERRIREGNQALSSEELIAWIEAVNTDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFEKQTVRLKHALDKYQKKKFTKGRKDTV
                     IQVPEIVMALLSKWKSVQAEQLLRLKINQTPDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPELAHLSPHKLRHTYATIARQGGANMNQISSALTHSDISTTRIYVNTPDVV
                     DKTVFEAFQRGLNKCD"
     gene            complement(2938..3330)
                     /gene="rpsI"
                     /locus_tag="IVD66_001121"
     CDS             complement(2938..3330)
                     /gene="rpsI"
                     /locus_tag="IVD66_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAP6145357.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(3346..3789)
                     /gene="rplM"
                     /locus_tag="IVD66_001122"
     CDS             complement(3346..3789)
                     /gene="rplM"
                     /locus_tag="IVD66_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HAP6145358.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(4308..4775)
                     /locus_tag="IVD66_001123"
     CDS             complement(4308..4775)
                     /locus_tag="IVD66_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HAP6145359.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(4895..6433)
                     /locus_tag="IVD66_001124"
     CDS             complement(4895..6433)
                     /locus_tag="IVD66_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HAP6145360.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            6513..7199
                     /locus_tag="IVD66_001125"
     CDS             6513..7199
                     /locus_tag="IVD66_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HAP6145361.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(7400..7927)
                     /gene="msrA"
                     /locus_tag="IVD66_001126"
     CDS             complement(7400..7927)
                     /gene="msrA"
                     /locus_tag="IVD66_001126"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP6145362.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(8011..8688)
                     /gene="pgmB"
                     /locus_tag="IVD66_001127"
     CDS             complement(8011..8688)
                     /gene="pgmB"
                     /locus_tag="IVD66_001127"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAP6145363.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(8685..9815)
                     /locus_tag="IVD66_001128"
     CDS             complement(8685..9815)
                     /locus_tag="IVD66_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP6145364.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(9815..11998)
                     /locus_tag="IVD66_001129"
     CDS             complement(9815..11998)
                     /locus_tag="IVD66_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAP6145365.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(11995..13020)
                     /locus_tag="IVD66_001130"
     CDS             complement(11995..13020)
                     /locus_tag="IVD66_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP6145366.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(13065..13892)
                     /locus_tag="IVD66_001131"
     CDS             complement(13065..13892)
                     /locus_tag="IVD66_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP6145367.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(13889..14956)
                     /locus_tag="IVD66_001132"
     CDS             complement(13889..14956)
                     /locus_tag="IVD66_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HAP6145368.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(14982..15818)
                     /locus_tag="IVD66_001133"
     CDS             complement(14982..15818)
                     /locus_tag="IVD66_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6145369.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(15815..16684)
                     /locus_tag="IVD66_001134"
     CDS             complement(15815..16684)
                     /locus_tag="IVD66_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6145370.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(16754..18037)
                     /locus_tag="IVD66_001135"
     CDS             complement(16754..18037)
                     /locus_tag="IVD66_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP6145371.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(18051..19736)
                     /locus_tag="IVD66_001136"
     CDS             complement(18051..19736)
                     /locus_tag="IVD66_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HAP6145372.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            20011..21036
                     /locus_tag="IVD66_001137"
     CDS             20011..21036
                     /locus_tag="IVD66_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6145373.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(21631..25284)
                     /gene="rpoC"
                     /locus_tag="IVD66_001138"
     CDS             complement(21631..25284)
                     /gene="rpoC"
                     /locus_tag="IVD66_001138"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HAP6145374.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(25363..28980)
                     /gene="rpoB"
                     /locus_tag="IVD66_001139"
     CDS             complement(25363..28980)
                     /gene="rpoB"
                     /locus_tag="IVD66_001139"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAP6145375.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            29708..30676
                     /locus_tag="IVD66_001140"
     CDS             29708..30676
                     /locus_tag="IVD66_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6145376.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            30694..31599
                     /locus_tag="IVD66_001141"
     CDS             30694..31599
                     /locus_tag="IVD66_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6145377.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            31596..32402
                     /locus_tag="IVD66_001142"
     CDS             31596..32402
                     /locus_tag="IVD66_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6145378.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            32559..33527
                     /locus_tag="IVD66_001143"
     CDS             32559..33527
                     /locus_tag="IVD66_001143"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HAP6145379.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(33844..34368)
                     /locus_tag="IVD66_001144"
     CDS             complement(33844..34368)
                     /locus_tag="IVD66_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinB family protein"
                     /protein_id="HAP6145380.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            34655..>35719
                     /gene="scm"
                     /locus_tag="IVD66_001145"
     CDS             34655..>35719
                     /gene="scm"
                     /locus_tag="IVD66_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAP6145381.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        10272 a         7539 c         6612 g        11296 t
ORIGIN      
        1 aataaatata gtatctccat aggctttttt taaattctct tcattaaata cagattctac
       61 acttccgtga gcaattagat ttcgattcaa aagaataata ttatcaaaat acttctttac
      121 cttgcttaaa tcatgatgca caattagcac tgtttttccc tgatgtttca attcttttaa
      181 cgtatccata attattcgtt cactaactaa gtctatccct acaaatggtt catctaaaaa
      241 tatgaaatcc gcattttgag caagacatct tgctaaaagt acacgttgaa attgtcctcc
      301 agataattct cctatttgat gattagaata ttttcccata tcgacctttt ccaaagcctt
      361 tgaaactctt tgccattctg catttttaat tctttgaaaa actttcattc cggcatatgt
      421 tcccatagat acacattctt ttacttttat tggaaaagta aaatcaatat cagctttttg
      481 ctctacatat gcaatcttca ccagtttttt attgatatct tcattattaa tggagacctc
      541 tccctgatga gggataatat ttaacattgc tttaagcaat gtagattttc cagcaccatt
      601 tggaccaata atacctgtta aagcaccttc ttgtattttt aaagaaatct cgttcaatgc
      661 taaaaaatcg ttataacaaa cattaagctt tttcacttct aacataactt tctccttcta
      721 aatgataatg attatcacga tcatatggta tacaaaaatt atattttagt caaccctaaa
      781 ttttataatt tagatttttt tctgttgctg aagattagaa tgacaaaact atttgaaact
      841 acgcgtatag taagtagctt tcaaaatata taaaaaagga gcgttctcaa atgagaacat
      901 gctcctaaaa ctactttatt ggcgtatgga aaaattatac ttaaagtgga tagcgggttg
      961 aataagttga taagcatcaa aacatttata aaaattattc aagactatgt ctgttccata
     1021 tacaaatatg aaaatcagta aactccattt aacttttttc gtagtgtgtc tttttataca
     1081 tgtttatcgt tattaatagt gaataggaaa aaacctattt ttgatcattg acaattaaat
     1141 acaatttttg aataacgatc cctgctattc gagctagaaa ctcaagtacg ccatgacctg
     1201 attagcgaca aatacttaga gatttctttt tgttctggga aaacaaaatg ccatgacaat
     1261 agcagcaaat aatgatactt ccgtaaggct cgccgtaaac tggggagagg tgaaattcct
     1321 atgtgcttac ccaaagcaat tcaaaaattc taatcttttt taggagatga ttttataaaa
     1381 ttgagagtct acttgaataa aaaacaaacc tgtgagtttc taggaattga taataatact
     1441 ttagataagt ggattcgtat atataatttt ccagtaatca gaattgacgg tatagttcgc
     1501 tttgacatag aggatatcaa agattttatg aatacattta aaacaatttg aaaatttctt
     1561 ctcgccgcat atactaagaa tagcgaaata tactgcctta ctttttaagg gagtgaggaa
     1621 ttttgcctac aaaactttca aatgggaaat ataaaactaa tctgaggtat ccaaaaaaat
     1681 tcagagaaat cactggaatt acatcagaaa agtatcaaaa agtatttcca actaggcaat
     1741 tggctattaa agccgaaaat gcaatgaaaa ggaaaattga aacagtttta agagaggaga
     1801 atgcaaattc actagaatta aaaggaaaaa taaaatttaa ggaattctat gaatcaaaat
     1861 ggcttcctag atatgaacta ggtcagacta ctagatcaaa aagagctcca agttacgtaa
     1921 caattagtaa tactaaagat atattccgat tgcacatcct tccaatgttt ggtgagtatg
     1981 caatgaacta tctaaattca aatactgaga taatatcaga tgaattaaca aaaaaatcga
     2041 aagaatacgc aaatataaaa attatcaaag gatatgtccg ttctatgttt gatattgcag
     2101 aaatactaaa ttatattgaa tttaaccgaa ctaccaaaat tattcaatgt atcactgcac
     2161 ctaaaaaaat tgctttagaa gaaagaagga tacgggaagg taatcaagca ttatcgtcag
     2221 aagagcttat tgcttggata gaagcagtaa acactgactt gaataatcac ttgcttactc
     2281 ttcatgacta tactcttttc atgcttaccc tatatcttgg tgatagaaaa agtgagacgt
     2341 atgctttgca atggaaatat atcgactttg agaaacaaac ggttcgcctt aaacatgctt
     2401 tggataaata tcaaaaaaag aaatttacaa aaggtcgaaa ggataccgta attcaagtac
     2461 ccgaaattgt aatggcatta ctaagcaaat ggaaatcagt gcaagctgag caattgttga
     2521 gattaaaaat taatcaaaca ccagatcagt atctctttac ctatactaaa ccatccggag
     2581 aagtaaattg ccctgttcac gctgattacc taaactatcg aatcaattca attaaaagac
     2641 gacatcctga attggctcat ttatctccac ataagcttcg tcatacctat gcaactatag
     2701 ctagacaagg cggagcaaat atgaatcaaa tatctagtgc tttaacacac tcagatattt
     2761 ctacaacgag aatatacgta aatacaccag atgtagtaga taaaactgtt tttgaagcct
     2821 ttcagagagg attgaataaa tgtgattagt atgtgttctt aaatgtgttc ttaaacaaga
     2881 aaaagacact tttcaaacaa ttgaaaagtg ccttgaaaca ttgatatata aataatatta
     2941 acgtttagag aattgagatg ctttacgagc ctttttgaga cctggttttt tacgttcgac
     3001 catacgtgcg tcacgagtaa gtaagccagc acgtttaaga gctaaacgga agtcaggatc
     3061 aacttctagc aatgcacgag cgataccatg acggatagct cctgattgtc cagcgtatcc
     3121 tccgccgttt acgttaacaa atacgtcata tgcgcctttt gtttcagtaa cagcgaaagg
     3181 ttgattgatt acttcacgca agtcagcatg tggaatgtat tcttcaacat cttttttatt
     3241 tacagtaatt ttgccagttc ctggtactag acgtacgcga gcaactgcgt ttttacgacg
     3301 gcctgtgccg atatattgaa cttgtgccaa tgaaattccc tcctattaga ttaagtttgt
     3361 gatgtctaaa acttctggtt gttgtgctgc atgtggatgt tctgctccac cgtatacgtt
     3421 caattttgta aattgtttgc ggcctaaagt gtttttagga agcatacctt ttacagaagt
     3481 ttcgatcaaa cgacgagaat ttttagcacg caattcgcca gcagtgattg atttcaatcc
     3541 tcctgggtag ttgctgtgac ggtaataaat tttgtcagtc gcttttttac ctgttaattt
     3601 cactttgtct gcattgatga cgatgacgaa atcaccagta tccaaatgag gtgtgaaagt
     3661 tggtttattt ttaccacgta gtacagatgc aacaactgtt gaaagacgtc ccaatggaac
     3721 atcagttgcg tctactacat accatttacg ttctacttcg cctggtttgg ccatatatgt
     3781 tgtacgcacg ttattttcct ccaatttaag ttctgatgtt tgacatacac ttcgagtttc
     3841 cggggctctt tgtggggcaa acaataccat ttaacatatt acccgctaat ctagtcaatg
     3901 tcaacgtttt tctgcttgat tgaaaaattt atatgaaact ttacttcttt tctttctttt
     3961 atataaaagg gtcgtttcct gtcaaaatga aaaacaaaaa gaggctgtga caaaagtctt
     4021 gtcacaaccc cttattttga ataaacggtg ttctcctgcc aactcctcgg tcacaagtca
     4081 caatatccat aaaacataag aagctgtttt ttaaaattgt ttcttgtgac tcggagctga
     4141 acggcaggct tacaacctct tggtaaacgg tgttcaatca gctgaccctc ggtattagct
     4201 caaaaaacgg caaaatatga ggaactattt tgacgtttgt ttctctaata ctcaggtcaa
     4261 aacgctgatt tcacaacctc tttttcggtc aagttcaaca acagttttta cgcgtcgatc
     4321 tctggcgctt tgcccaaatg agcttggatc atccagatac gtttttctgt ggctgttttg
     4381 aattcgataa agatatcttg tgttggatcg tcgccttctt ctccagaaac ttcgattcct
     4441 ttttggtaaa gatctgctag ataacgatag cctgcaacaa gtgtttccaa acgttctgga
     4501 atagtacgat cccagcggcc aatttcatca gggatttttg tgttatctgc aaattcacgc
     4561 aatgtagaat aaggtgaacc gtctaatgtg atcaagcgtt cggatacttc atctaactga
     4621 gcgttcaaat catccatgaa ctcatccatc attgggtgca atgtaaggaa acctggtcct
     4681 ctcatgtacc aatgtgtttg gtgaacaaca acagacattt ggcttagatc tgcaactaat
     4741 tgatttaata cttctttggt ttgttggaat ttcatctttc ttgcctccta acattttctt
     4801 acacttaaaa taatagtaga ctttcaatga aaagtacaac aaaatcattt acctgagaac
     4861 gattttcagt tcgctttttt atccgtaaag ccaatcattt ttcagaatca gctaattctt
     4921 ctcgcagttg agcaaattgc tgataagtct gtgctaaatg cttttgtgtc gaaacaaata
     4981 atggatagat tttctgatat tttttatgat cagtttcttg tactccaact tgctctttca
     5041 attctatcaa ttcctgtgct tcactgatac tttggatctt tccgatgctt ctccagccta
     5101 aaatcacagc tcctaatgcg gatgcttctg tgacagtagg gaaaacaagc gggtaaccca
     5161 gtacatcagc catcatctga cgaaaaatcg gagattgagc aaacccgcct gtagcacgga
     5221 tctctgtgag ctgattttcc tggcaaactc cttttaaaat ccgataaagg ttgagacaga
     5281 tcccttctag aatcgccttc atcatttctt tttctgtatg ttgccgctgt aaaccgataa
     5341 aactgccaaa cgcatctgcg tcccaaagcg gtgctcgctc accaagtaaa tagggatgaa
     5401 aaatcagacc attggcaccc gctggcacaa aagcgatagc cgaaagcagt gcatcatatg
     5461 gattttctcc tttttcttta gcagattgaa cgacttcctg taaaaatgta tgccctgccc
     5521 aatcaaagat gccagcacca ttgctagtcg ctcctcccac tacccaatgt ttctgatcca
     5581 gaacataaca aaacgtctcc atttctggat ggaactgagg ctgagtagta ataaaacgaa
     5641 gtgctccgct cgttcctacg gtcaaagcgg cgatcgtatc accaaaagca cctaacccta
     5701 gattagaaag cggcccgtct gcccctccca aaacaaatga tatatcattt ggcaaaccta
     5761 gttctgctgc tgtttttgat ggtagacctg ttacttgata ggtggaagga aagacttgcg
     5821 gcaattgctc tattcgaatg ttcaagtagt caagcacttc ttctgcccat tggaattcat
     5881 ggatatcaaa atatccagtt cctgaagctg ttccgtagtc gctgatcagt tcgccaaaca
     5941 atctataaaa gatatagtct ttgataccga caaaataagc agtttttttg aataattcag
     6001 gttggctgtt ttgcagccac ttgattttgt tcaatggtgt cattggatga atcggcgtcc
     6061 cagtctgccg ataaaattct ttgccaagca cggtatattt cagtttttct gcttcgtccg
     6121 ctgctcggtt atctgcccaa gtgatcattc gagataacgg tgttttctct tcatccaaca
     6181 atatcaggcc atgcatcgca gaggagaagg agacaaattg aatgattgtg tctgaaggca
     6241 actgtttaat tacttctttt ataacggtgc agacaccttg aaagatcaat tcctgatctt
     6301 gttctgccat cccttgtgtt tcttggatca aagggtagcg aaaataagcg gatgctgctt
     6361 cttgggcttc atctgtgaaa gcaactgctt tggtttgtgt ggttccgata tctaatccga
     6421 ttgaaacgtt cattttttca cctcaaattt tatgtatgta caaaaattta gtttaagctt
     6481 gcgtatcttg gttttgaaaa gggggagatg gcgtgttact ttattttatc attggttgct
     6541 gtatcggatc atttttatgt ttaaccgccc agcggattcc gttaggtcac tctattattt
     6601 atcctagatc tcattgtgtc aaatgctgtc gttcgctttc ttggtatgaa ttgattccga
     6661 ttctctcgat catcgtccaa cgatttcgct gccgctattg caggtgtcgg ttgcccttct
     6721 actatttgtt ggcagaagcc ttatgtggtg gtctttttgc ctggttcttt actttttctt
     6781 ccgcaagaaa tttttcgacg ttcatatgga tgctttcggc tttgctattt tcgttgatgg
     6841 atttatttta cttcatggtc cattctcaca cgctattctg ttcttgggca attttatgga
     6901 ttttttggtt gcaggccggc gtcttccaat ggcaaagtgt gctgttaacg tttatcgtag
     6961 gcggtgtgtg ccttcgctat ggtcaatcct atctcggagc tggcgatact ctgttgatgc
     7021 tttcttggag tggtggcttg tctctagaag agttgcttca gatcttgttt cttgctagtc
     7081 tgtttggaat atccgttttt tctgtttact ttatctgtca taaaaaaaag ttggaaaagc
     7141 tgcctttcat tccttttttg agcagtgcgt tgctgattgt ccttcatctt aggtattgaa
     7201 aaaaggttgt gacaaacgac ttgtcacaac ctctgatata tagtgttctc ttaccaaatc
     7261 cttgtgactt ggagctaggc gacaggttca caacctctcc actaaatggt gttcaatcag
     7321 ctgaccctca gtattagctc aaaatgctgg ttttacaacc tctgatatac ggtgttccat
     7381 aagtagcttt ttcggcttct tatttcttga cgccccaatg tcgacgaagg aaacctgcac
     7441 gtccagaacc ttctcgataa agattgtaat ggagcttgtt tttcttgtaa taatcctgat
     7501 ggtaatcttc tgcaggataa aattcgcttc ttggttcgat ttttgtcacg attggcttat
     7561 cgaatcgccc gctgtcttgc aatgcttgtt ttgaacgctc tgcaatattt cgttcttctt
     7621 catcattata gtagatcact ggacgataag aatcaccgcg atcagcgaac tgtcctaatg
     7681 cgtcagtcgg atcggtttgc tgccaataga tttccaccaa ctgatcataa gaaataactt
     7741 ctggatcata ttcgatctct actgcttctg tatgccctgt tgtgcctgtt gttacttgtt
     7801 cataagttgg atttggtaca tgcccgccag tataaccgga tgtcacagaa atgatccctg
     7861 gctgctcttc aaatggtttg accatacacc aaaagcatcc gcctgcgaaa actgcttttt
     7921 ttgtcatata aaatccccct tttttctcat cataccttga tttccaaaag gaggataacg
     7981 ttttgcttgt gacagaaaaa acggaaacta ttatatacgt gatacggctt ctgataaatg
     8041 ccaaaacgaa cgtacttgat caaaaacggt taaatcagga atcacatatt cagcagaagg
     8101 aagatttatg ttttcaccta ttcccaatac atgcatgtta ccagccaaag ctgcttgaca
     8161 accagcttct gaatcttcaa tgaccaagca tgcatttggc ggtacattca attgctgtgc
     8221 tcctttgaga aaaacttctg gatcaggttt tgcttttgat acttgcgtgc cgtcaataag
     8281 gacatcaaaa taacttgtca aattcgtttt ttctaaaatg aggcgtgcat ttttgcttgc
     8341 tgatcccaat ccgatcttga tgtttgtttt tttcaagtac tcaagaacag ctattgcacc
     8401 aggcaaaacg gatgtttcat ccattttttg aatcgcttga agatatagat tgtttttttg
     8461 ctcagcaaag gctgatttct ctttttctga gaatttctgt tccatttttc caaatgacag
     8521 caatcgctct agtgactcgg ttctggatat tcctttcagt tgctcgtttt ctttctcagt
     8581 gaatggaatg gacagctggt tagctaaaac cagccacgct tcgtaatgat aacgagctgt
     8641 gtctacaaga acgccatcta aatcgaatag tgctgctttg attttcatcg attacctcct
     8701 tgaaaatgaa cgacttgaag taaagatgcg atgtttttag ctgtgcgatg aagattatca
     8761 gtggcttgct gtaaagcttc ttgtaaaggc acagctgcag gaaggatcgg aaaaacggcc
     8821 gaaatgccaa catctgctgc tttttcgctt cctttaccaa cacttccgca aatagctatc
     8881 acaggaacgc cctctggtac tcttctagca atcccaactg gcgcttttcc ttttagactt
     8941 tgtccatcta gacgtccttc gcctacgatt acgaggtctg cttgctgtac ccgtttatcg
     9001 aactccagta aatccaatac gtagtcgatg ccagagacta ttttccctga agcaaatgct
     9061 aacagtcctg cacccattcc accaccagca ctactgcccg atgcctcgat tacttgaggg
     9121 gcaaatctca tataaaaatc atgcatggct tggtcagcca ctgctaattc attttctttc
     9181 aagccttttt gtggtccgaa aacaaaagaa gcgccttctt ttccgcataa aagattagta
     9241 acatcagtaa tgacagtgat tttggcttta atcagctcaa taggcacgtt cgttttatca
     9301 actgtagcaa ttttacctag attttctccc agtgcttcta ctttttgatt atcttgatcg
     9361 taaaaagcat aacctagacc ttctgccatg ccgatgccgc catcgttggt actacttccg
     9421 ccaacgccga tgatgatgtg tcgaacacct tgttgcaaca attgtcgtat cagttctcct
     9481 actcctcgcg tggataacct aagtggctgt tgttggttta gtgggacatc tttcaatccg
     9541 acgatttctg ccatttcaaa aatcgcagtt tgaccgtctg aagcgtactg gatttctttg
     9601 tttttgccaa atgcattagt aacgactgct gtttgccgct tcaaccttaa actgtctgct
     9661 aatgatgaaa ccgttccttc tcctccatcg cctataggta gcagatcata ttcagcctga
     9721 acaaaaactt cttgaaaacc tgattgaatg gcttgtgctg cctctaaggc tgtcagactt
     9781 tctttgaaag aatctggcgc aatcagaata cgcattattt tcccctccgt tccaagatca
     9841 gttctttttc cagctggtat tggtctccat tgacaaaaat aggtaatgtt tctttcgtct
     9901 ctttttttat tactatttgt ttttttgtca aaacaaatag caacctgtga tttttccaaa
     9961 taaaaggaaa agaaattttt tcccatgctg aaggaagtct tggagaaata gaaagagttc
    10021 cattcgttac tgtaatacct gaaaaaccaa atataactgc tagccatagt gctcctaatg
    10081 aagcagcatg aattccgtca tctgatgaat gcggatctgg tcctaaatca atcaggcacg
    10141 cttcttggaa taaatgatac gcccattcca tttcttggat acggcaagcc tctatggcgt
    10201 gaatcgcttt actcaacgat gagtcgtgga ttgttttgtt ttcatagtaa tgcaaattct
    10261 tagaaacgat tggttgagaa aaatactcag gtaataagta taacagcatg acaagatctg
    10321 cttgcttgct gacttggagt tcatttactt cgctacgggc ataatcaagt aaaatagact
    10381 ggctgccagg acgttctttg taagtggtca aatcaataac tggcttactg agatacgtgt
    10441 catcttgcgg aatcagctgt tctttgttag gcactggcaa atataactta tctaaaaaat
    10501 tttgacattc tttcaaaaaa agcggatcgc cagcttgata tttaacagct aaggccacat
    10561 tataatgcgc cagatagttc gtatatgcat tattgtcgat atattctgtg tattcatctg
    10621 gaccaatgac tctgtgtatc tctaaatgat catcgacttt tacagctctg ctcagccaaa
    10681 aagctgctgt ttcatgaatg agcgtttttc cctttgtttc taaaaacgat tgatcctctg
    10741 ttgcttggac atactcttga acggcataag caaggtctgc actgatatga tgttctgcgg
    10801 cagctgaagc aacttcttgt cttgttccgg ttttgatatt caatgcagca aatttgggtg
    10861 tctcttcctg accagtgtgt gcgctttccc atgggaaaag tgcaccttga tagtgataat
    10921 ctcttgcttt ttgccgtgcg ccttctaatc gatcataacg gtacagcagc aaattctttg
    10981 ctacttcagg aaactgatat aaaaagaaag gcaggataaa aatttccgta tcccagaaaa
    11041 catgcccttt ataaccttcg ccagttagtc ccttcgcccc tacactaaca cttggatcat
    11101 tgcggggagt cataatctgt aaatggtaag cagcgaagtc catcgctaac tgatcgaaag
    11161 aagaatcgcc ttggatcgtt atccgatgct gatgccaaaa atctgtccaa taagacatcg
    11221 actgctctaa aatttctgta taactaacgc ttttctgggc ttgggcaata cttttcttaa
    11281 acgggtctgt ttgctgaaga gaggtagaga gcacgatgat cttctccagc gtaaaggacg
    11341 tattttttct gatcttttct gaaaaggaag cggtgatccg gcgatttttt gcttggaata
    11401 cacctgcttt attgaattta gctgcaatcc caatatcaat tttactttct gttgtctggt
    11461 aggatgcact gatcaaatcg tcaccaaata ctcgcagttc tttttcaacc aactgctgtg
    11521 taccaaaatt ggtttgctgt ccatcgatac ccgttttcac atctacttgg cagtcttcgg
    11581 tcaacggctt gatgaccact ttcagggctg cctgatggag attattttga tcagcaacac
    11641 gacaagtaat gacttccact ttttttcctt gagcagtttc aatgagcgca tagcgtttaa
    11701 gctctcccat ttctaaatct agtgcccgct cgtatgcaag aactttcatc gtctcaagag
    11761 aaaaatgttc accgtcgatt tttatttccc atctgatgac atctgggaga ttcactaact
    11821 cggctgattc tgctcctaaa ggtcggttat atacaccagc tgcaaacatt ccccttactt
    11881 gattccgata gtcttcctcc tggcttcctc tgataccaaa aaatccattt ccaatggtca
    11941 tctgactcgc atacttattg atatactcta aatcaaactg tttttcttct actttcataa
    12001 ggtaataact tctcctgttt ctgccgaacg atataaattt tccaccagat tctggatgac
    12061 atatccttgc cagccatctg caatcatctg agtctggtca ccgagcgccc gattcacaaa
    12121 atgagccata cttagttcat gtgggtcatt aactggcgtg gtcttttgta aggaaaccag
    12181 ctttccatct acatcttcga atagttcgcc tggatacaga ttagcacctg cctgatcgcc
    12241 acaaaaagcc acattcagtt tgtcttctct gatattcaaa gcaaacgaag tattcagttg
    12301 gatgatcttg ccgttttcta attccagtgt gccaaaaatt gcatcttcta ctgtgaattt
    12361 gcttggatcc catttcccga atttccctga attttttttc gtaccaattt tttggaagct
    12421 gtacgcccga acgcttttta ctttaggaaa tccagtaata tacatcgctg tatcaagcat
    12481 gtgaatgcca taatcgatca aaggcccgcc tccttgaagt tctttgtcga taaacgttcc
    12541 ccagcctgga acaccagacc gacgaagcgc attcgcttct acgtaataaa tatccccgag
    12601 aacatcaaga tgattcttga tcattgttgc ttcgtcagaa aaacgatgct ggaatccata
    12661 agccaaaatc tgcccgtttt tatcggctgt ctctgccatc tttcttgctt gatcagctgt
    12721 catagctggt ggtttctcgc acatcactga agcattagct tcgagggcag ccaatacatg
    12781 ttcgaagtga aagcgattgg gtgtacagac actcacgata tcgggagaaa tctcattcag
    12841 catttgtgta actgatgtat acgcatgaga aaatcctgta cgtcggcaaa agtcttctgc
    12901 tcgctggctg actggatcaa ccacagcggc caattctaag acatctgatc ttttttgata
    12961 ataagcagca tgtacttttt ctgctacttg tccagcgcct atgattgcta ctttcttcat
    13021 ttatttctct ctcctttgct tatttactta ttgttattct ttctctattc tttctctaaa
    13081 tcatttaaat gacgcgctgt ttccagacag tttttcaagt attgcaatga ttcctgataa
    13141 attttcactt cattttctcc tcgcaaacga cattcatata ccatataacc ttcatactca
    13201 ttttgaagta gcgtttgaaa atggcgagta aaatcaattg cgccagatcc tggttggtag
    13261 cgatgattat ctgctaaatg gatatgaccc acatactctt tttgcgtagt caatgctttt
    13321 gaaatatcat cttcttcaat attcatatga taaaaatcag cgatgatctg cacatgtttc
    13381 aattgattag agtcaatgta atgacgcgca tccgctaaca aattgatcat atggtcttgg
    13441 tatcggttca aaggctccaa ataaataacc gtacctgttt cttcggctac tttatctaaa
    13501 taacgaagtg attcgctgac tgctttatag tctccttctt tgcttcgggg tgaaaccatc
    13561 ggcggtaatc gataagtgaa cattccccaa gctgctggga taacgattcc tttgcctcca
    13621 acctcgctta gtgcacgcaa aatctcagca atttgacgta caccattaag acgccgttct
    13681 tcgataaagt caccgatcca cccatcgtag ccgttacaag ctgtcactac tgggatccct
    13741 gtttctttga ttgcctgttt gactgtgtcg atattttcta ttaacaactt accgtcgatt
    13801 tcgtattctt caaatccaca gtctttgata aatctaaatt tttctaaaat gtctcttggg
    13861 aaaaatgctt gatcttgcgt accgaatttc attgttctcc tcctcggact tgaacgccca
    13921 ttttgatact ttcttctggg tgctggtcta cataacgcat gtaagcttct gcgctttctg
    13981 caaatggcac aactggatca atgatttctt cacaatccaa gtaaccgttc atcaataatt
    14041 cccaacatgt gtcctcgatt cgtttacggt tccatcttgg gtaatctggg tttggttcac
    14101 tagatgctcg agcaaagacg atttttgcat tattgaaatg tgcttcgcga ccaagattaa
    14161 acccagctgg aaaaggttta gcaaaggcaa cataagaaat gatcccgcca tagccgatcc
    14221 ctcttaaaga agcttgtaat gcggcagcac tgccactcgt ttcaataact gaatctactc
    14281 cacgtttatc tgtcaattcc tttagacgaa aaccgacatc tgctttcata ggatctagcg
    14341 tgtaatcggc accgtatttt tctgctaatt ctctacgctg cgctatggga tcgatcccaa
    14401 cgatggtagt agcacctgct tttttagcta attgaatcgc aatttgcccg atagcgccta
    14461 aaccgaagat tgctacagca tcacctgctc gaacatgtgc ttcccggata ccacctaaag
    14521 cgaattgagc aggatcgtaa catactgcat ttttccattg atccaaccga tcaagtttac
    14581 gtagtttata attatcaaca ccgtttgtaa tcagcgtttc acgaatgggt ccataagtgc
    14641 agactaactc tcctttttga tactctgtca ccaaactgcc cgtttcttcg atcgtaccga
    14701 caatcatatt tcctaattga aattcgccaa ataccacacc gcgttggctt ccttcttctc
    14761 ttggcaagaa taggcgccat tcttctgaaa attcttcatc gataaatgga cttaatcctc
    14821 taaagtcgac aatttctgtt cctggttttg gagtagcgaa aattactcgg atacgtactt
    14881 cgttcttttc gatctcacgg tcttcgtaat ctttgaatcc ggctattctt ggttctaatg
    14941 caactaattt tttcatcttt tctttcctct ttcttttctt tttatccttt tacgccgcct
    15001 tcgactaaat cacctttaat aaatcgttca gataacgcat acataatgat gactggtaaa
    15061 gcggtcacca atgaagcggc catcattcgt ccccaaatgt agtctggtgt actgaataat
    15121 gtgttcaaac cgattggtaa agtaaatttt tcggaggtcg acaggaaaat cgaagcaaat
    15181 aaataatcat tccacgaaac cataaagcaa taaacgaaga cagaaatgat tccagaaata
    15241 gccaatggta taatgatccg aataatgatc tggatccggc taagaccatc gatcattgct
    15301 gcttcttcaa tatcagtcgg aatcgtgtca aaataacttt ttagcatgaa tatcgcagta
    15361 ggaagtgttt gaacgaccat cgtgataatc agtgctgtat tggtatcata caaacctaga
    15421 ccggaaatga ttttaaataa tggaacaacg atcaaaatac cggaaaacat ataaacggtg
    15481 taaaagctag cattgatttt cgagcgagct ttgaagcgta gttttgacaa agcgtatgcc
    15541 ccgctgatcc caatcactac tgcagttacg gaggctatca aggagatcac taaactattt
    15601 ttgaaataca tgatgaatgg aaaaatctca gcattgaaaa tatcctgata atgttcaaaa
    15661 gtccattctt tcggaaaaat agtttgtgtc gttgcaattg cttcttgtga atccttgaat
    15721 gatgtcatca gcatgatcaa aaatggaaac aaattgacag ctaatagcaa caaaatcgtc
    15781 gcgtaaaata agattttcct gctcttttta tttttcattt caagtccacc ttctttcgtg
    15841 agagcaagac gaccgctgca ataatgatga acaatagaat cgatatagct gctgcttttc
    15901 caagatcatt gaacgcaaag gctgtctgat acaaataaac gcctaagata ttgactttat
    15961 tcgtcagtag atagacatct gtaaacatat agaacatcca gatagatcgt aaaacaatca
    16021 cagttgctag tactggtttg attgccggca gtgtcacgat cttgaacttc tgccaagcat
    16081 ttgcaccgtc catttcagct gcttcataaa gcgttttgtc gactgtttgc aaaatagcca
    16141 aaaatgaaat aaacgcatac ggatagtatc tccagatagc aaacaaaacg accataaaga
    16201 agctagcaac tggctggtcg aaccacagcg gtgcttcgtt gaaaagctgc aacctatcta
    16261 ctaacagatc attgacgatt ccataactat tattgaacat atatttccaa gcaaaaatca
    16321 aagaaataga tggcgtaaca taacttaata aaatcagtga acgcaccgtt ttcctaaatc
    16381 tgaacttgcg gttaagcaaa atagctacgg ctaatcctaa agctgtactg cctgctacaa
    16441 ctaagaatgt gtaagcaact gttaaaccta aagaacgata aaattcacta tcacttaaaa
    16501 tttcaagata attgcttaat ccgataaaaa cggcgtctga gttaggattc agcggcatat
    16561 cgaaaaaact gatctgaata ttggaaagca ttggaatcag cactaaaaca gctaataaaa
    16621 gcatgcttgg tgctaaaagt cccatggcta attttaagtc agaatgtttc cttggacgat
    16681 tcattgaaac ctccccctga taatctgcca atagctatct acttttttcg aacaccattg
    16741 gcagaacttc ttgttatttc gtattttttt gtgcgtcagc taaagcttga tcgacatctt
    16801 cgtttccgac agttacttgg ttcactgctt ttccgatcac acctgagctt gtgatatctc
    16861 ccattttcgt gaaattcttt tccccgacta gtccaaagac ttgtacttca tcaaaagcac
    16921 tagcaatctc agatggcagc tcgccaaaag acttgatgac ttcattttct ttgtaaccat
    16981 ccagttcgac tacttgttta ttcactggtt gagcaccacc aggagacatc aagacccact
    17041 tttccatgtt tttcggttga gataagaaag ctgtgaatgc ttcagcagcc tctttttgtt
    17101 tctcgtctag accagaagaa atcgtcaatc cagatactgt gccatagaca gcttgatctt
    17161 tttgtgttgg gatagcaaaa ccgatatttt ctgagttccc cgcttcataa acagaaggca
    17221 aaatgtaagt tgaatagatt gccattggtg ctgttccatt catgaaagca tctttgattt
    17281 ctgtcacatc attagagcct ggcatcgtgt attgggataa gttttgataa aacgacaatg
    17341 cttctctcat cttttccgta tcgatcgtta cctcgccttc atcatccaaa acatttgctc
    17401 catttgacaa agcaaattga gagaacgctt gctcactcat tgttccttca gcagtaggca
    17461 tagcaattcc atattgttta ttctctttat ctgtgaaatg ttgagcaatt tttaaaatat
    17521 catcccaatt ttctggttct gaaaaaccag cttctgataa tttttctttg tcataccaaa
    17581 taccttgaac ccagccgcta attggtgcag caatatagct ttttccatct tctgaacgaa
    17641 caaggttttt ggctccgtca taataattat cttctccagc ttcctcgata acgttttgga
    17701 ctgccgtctg atcaatcagt tcatctttat ccatcacttt agcaaaatcc tgactgactt
    17761 ccattacttc tggtaattta ccggaacgag ctaacgtaac gatttttgta ttgaacgctg
    17821 attcttctac cggcacttgc ttgattttga tgtctggatt ttctttttca aaatcagcaa
    17881 ccagttcatt gatcacactt aatcgttcct gttcgacaga agagtgcatg aattgaatcg
    17941 ttgtctgttg tgattcgtta gagctttgac tttcaccaca agcagtaaga agaaatccag
    18001 tagctagcag acaggtagta acaataattt ttttcatttt tttccacctc ttattttatt
    18061 attttcagcc acatatattc atacggctgg aatatcaact ttcgttcttg actgcaatgg
    18121 ataatttgtc cagaaaacag gtctaggtaa tctccttttg gtaaaagata acctgctgat
    18181 tgattggaaa aattatggat aactaagact ttctcttcct tcgcttcgcg aataaaactg
    18241 ataaaagaat ctgctgagtc cagtaagtaa atcaaactat tcggatggaa ggctttttct
    18301 ttttttcgaa tagatagcat ctgggtcaat tcaccatata ctgctgttct taatggatct
    18361 gtctgcaact ctttctcaat atctgctaac aaaaattttt gccgattgat ttttcgattc
    18421 tctcctgttt tttctacgcc tttgtaatca tttcgacttc ccagcacact ttgaatataa
    18481 attgccggca cgcctggtaa cgttaccaaa aatgaatgag cagctaaaaa gcgtttgctt
    18541 ctccattccg tcgtatctgt tggagaactt aacgcatcta gatacgtagc gtttatctca
    18601 tatggactgg tcgttccatc tgggtttttc ttgtagttta ctcgggcacc ctctttcttc
    18661 agctgttcca ctaattcaag gatcgttttt tccggcagaa tacctcgtac cggattcaat
    18721 ccgataccgt catgggaggc taaaaaatta aaaaaagttg tttttttcga tgcgaaatcg
    18781 atggttttta accattcttt caacttactt gtattacccg aacgaatcgc ttgaagggtc
    18841 aaaggtggta gcgaaaactg atagaccatc tgtgcttcat tctcgccatt cccaaaataa
    18901 ctgatattat ctttgtgtgg cacatttgtc tcagtgatca ataccgttcc tggagctgct
    18961 tcatcagcga ttgcacggaa taattggatg attttatgcg tttctggcag gtgtatacaa
    19021 gaagttccta gttctttcca taaaaatccc acagcgtcca agcgaataaa tgaagcgcct
    19081 ttttctaagt aaaacaaaag aatatcgatc attttcaata aaacttctgg atttttaaaa
    19141 ttcaagtcta cttgatcttc gctaaaagtc gtccatacgt gtttttcttt cccgtttttg
    19201 tcaatgaacg ttgtaagtaa cgggctggtc cttggtctag tcacgctgct tgtatctgta
    19261 tccagtggca aatcaataaa aaaatctttg tacgtatcat tcaagtttaa atattcctga
    19321 aaccaagtac tttcggcaga catatgattg cagacaaagt cgaacattaa ccgtgtttcg
    19381 cttctcattt cttctatatc ttcccatgtg cccaaacggt cgttgattgc ctgataattt
    19441 acaacggaga aaccatcatc agatgtatat gggaaaaatg gcaagaaatg tacaactcta
    19501 aatgtatctg ccaaatactt ttgataaaat ttcttaaatg tacgcaaagt tggttgctgc
    19561 tcttcaaaaa attgatcccc ataagtaatc aagaaaatat cttcttcgtc ccaatgcagt
    19621 ttgcctgcct ggcctttctt ctgctgataa acactgactt tttgttcaat catagaggcg
    19681 gttttctcag acaaatctga gtcgcgataa atcgcttgta aaagttttgt atacatcgga
    19741 ttcccctttc ttttttggga gcgttcccaa cgatttgatc atattatgga aaacgcttac
    19801 tgtcaatagc atttttttaa ataattttga tatacacaaa aatacaaata agaaagctta
    19861 tgtatcaata attaatagct tcttaaaaaa atatggtctc tcatgatcat gcaagctatt
    19921 cctaaatttt caaaatcata gacaaaaaag aatgtctatt gtactatgga attattctaa
    19981 aacgctccca aaaaggaggt gcatataaaa ttgaaaccta ctatttatga cattgcgaaa
    20041 aaagctaatg tctcaaaatc aactgtctcc agagtattaa ataaccagcc aaatatctct
    20101 gataaagcaa aagcaagtgt acttcaagca atcaaagaat tgaattatga accgagcaaa
    20161 attgcaagag gactgtcagg aaatggtttt gacgcgattc tagcattatc tcatcgtact
    20221 tctcatacga cctatggcaa tccttttttt tcagatgtta ttcaatccat ttctgccgtt
    20281 tctgaacaaa ataacttcga cttgattcta caaacggcaa aaacaccaga agaagagcta
    20341 gaaaaatgcg cgaaaaagat ccaagaaaaa atgatccgag gaattattat tttaagctct
    20401 acgatggatg aaacacttct ttttgaattg gatcaataca atattcctat tgtggtaatc
    20461 ggaaaagtcg gaaacgacta cacgaacatc tactcagtgg acacggataa tttccaggat
    20521 agttacgatt tggtggaaac actgatcaag aatggacacc gtcatatcgg ctgtctccat
    20581 gctccgacag aagtttatgt atccaatgat cgtctcaatg gttaccgtca atgcttattt
    20641 gatcaccacc tagatatccg taatgaatgg attatagacg gcggctttcg cttagaagat
    20701 agcatggcag caatgaatga tttaatgaag ctacgagaaa gaccaactgc gattttttct
    20761 accgatgcat taaaatcatt gagtatttac aaagtggcag aacaatctgg aaagcagata
    20821 cctgatgatc tttcgatcgc aggattcagt gatcccttat tgtcctccct attttcgcca
    20881 cagttgactc ggatagacat tccgacaaat cagttaggaa tcaaagccac agaactttta
    20941 ttccaactaa tccaccacca ataccctgaa gaaaaaagaa tcattctttc aaccgagatt
    21001 actctcacag attcgatcca acaacaagaa atgtagaaca gaattataaa agaacagaaa
    21061 cactgaggat aagtcagtta ctctgttctt ttttcaatca ctcatccctc gttaccccct
    21121 cccggtattt tagcgaattt ttcttatttt ccatctgttt tagatagctg tggataacta
    21181 taatgtttgt gttaaactat tttttccaca gggaagaaaa aactattttt aaccacgttg
    21241 tgtataagtt tttatagttc gtttttttaa acacatttac ccttatttca atccatgtta
    21301 tttggggata cttatctcta aaacataaat agaataacag acatgtctac tggttttgtt
    21361 ttattcgagg aattattcaa taatagctag caaaatatta aaaataaccg ctctatcttc
    21421 ccatcaattt attttgcatt caaaaaatga tctatcttta cttttgttga ttgacttctc
    21481 ttggaagatg atcgttccga taccttaatt ggatacgaac cgatgttgtt aagatccttt
    21541 cccacttttc ttctagttag acaaattatt ttagacaaac caaaaaagag gttgtgacaa
    21601 taatttgtca caacctcttt tttaaaatat ctattttgtt tgattgttca ttgcgtcttc
    21661 tgcagccatt tgcgcttcaa tatctgaaat actgtagaca ttttcgcttg ctacaccgac
    21721 ttcttttggt tccatgtcac gataacgttg cataccagta ccagctggga tgatcttacc
    21781 tataataaca ttttctttca aaccaagaag aggatctttc ttaccgcgga tcgcagcatc
    21841 cgtcaagaca cgagttgttt cttggaatga tgcagcagat aagaaactat ttgtttctaa
    21901 tgatgctttt gtgataccta gtaagacagg tcgagaagtt gcaggaacgc ctcctgagac
    21961 tagcgtattg tagttttgat ctttaaagtc tgcgatgtct aataatgtac ctggtaagat
    22021 atctgtatca cctggatcca ttacacgaac tttacgcagc atttgacgaa ccattacttc
    22081 gatatgcttg tcgccgattt ctaccccttg catacggtaa acacgttgta cttcacgaag
    22141 caagtagttt tcaacagata atacatcgcg aacttgcaac aattgttttg gatcgattga
    22201 tccttctgtc aatggtgcac cacggtggat catatcgcct tctgctactt tcatacgtgc
    22261 tgtataagga acagtatacg tacgtgtatc tgtttttcct ttgattgtta cttctttggt
    22321 acgtgttgca ggatcttctg agatatcgat gacatcccct gttacttctg tgatcactgc
    22381 ttgccctttc ggattacgtg cttcaaagat ttcttggaca cgaggaagac cttgagtgat
    22441 atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc gtcaactgag taccaggttc
    22501 accgattgat tgagcggcga tcgtaccaac tgcttctccg acttcaacgt cagagccagt
    22561 tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt tttgtattac atgtgaagac
    22621 agaacggatt gtcactgttt cgacacctgc atcaacgatt tgttttgcga tgtcttcgga
    22681 aatcaattgg tttcctgcaa tgatcaattc atttgtttca ggatgacgta cttctttacg
    22741 ggtgtaacgt cccactaaac gatcttctaa tgattcgatg atttcatttc cctcgcggat
    22801 ggcttggatt tcaagacctc ggtcagtacc gcaatcttct tcacggatga ttacatcttg
    22861 ggccacgtca accagacgac gagtcaagta acctgaatcg gcagtcttca aggctgtatc
    22921 ggtcatccct ttacgagccc cgtgagttga gataaacatt tccaagacgg atagtccttc
    22981 acggaagttc gaaatgattg gcaattccat gattcgacca ttaggagcgg ccatcaaacc
    23041 acgcattccg gcaagctgtg taaagttgga aatgttacca cgagctccag aatcagacat
    23101 catgaagatt ggatttttcg cttccaaacc ttccatcagt ttttgttgga tgctgtcttt
    23161 tgcagcattc caaacagcaa tgacacgttc ataacgttcg tcatctgtga tcagaccacg
    23221 acggaattgt tttgtaatag tttcaacttg tttatgggca ttttcaatga tttcttgttt
    23281 ttcattcagt acactgatgt cagcgatccc tactgtgata ccggcatgtg tcgaatgttt
    23341 gtaccctaag tctttcatac ggtcaagcat cttagaagtt tctgttactt tgaatcgttt
    23401 gaagacttct gcgatgatgt ttcctaagtt tttcttcttg aacggtaata ctaattcttg
    23461 ctctttgata tgtgcaggaa tatcagtacc agcttcaaca aagtatttgt ccggtgtttg
    23521 gacggtcaag ttgaagtctg ttggttcatt cagataaggg aattcaggag gcatgatctc
    23581 gttgaagatg atcttaccaa ctgttgtgat catcgtacgt tctttttgcc attcagtaaa
    23641 tggtttttca cctaatgagt tagggttcac accgatacgt gaatgtaaat gaacatatcc
    23701 gttgcgccat gcgataacgg cttcgttttg atctctgaag accattcctt cgccttcgcg
    23761 tccttcttct tccattgtca agtagtagtt acctagaacc atatcttgag aaggagtaac
    23821 aactggttta ccatctttag ggttcaagat gttttgagca gctaacatca acatacgtgc
    23881 ttctgcttgt gcttcttcat tcaatggaac gtggacagcc atttggtctc catcgaaatc
    23941 ggcattataa gcttcacata caagtggatg caaacggatt gcgcgtcctt gtactaaaac
    24001 tggttcgaat gcttggatac caagtcggtg aagcgtaggt gcccggttca gcaatactgg
    24061 gtgttccttg attacgtctt ctaaaacatc ccatacttcg tcttcttgac gttcgatttt
    24121 acgtttcgca tttttgatgt ttgaagctag ttcgcgttga acaagctcac gcatcacgaa
    24181 tggtttgaat aattcaatgg ccatttcttt tggaagtcca cattggtaca tcttcaagaa
    24241 aggtccaaca acgataacgg aacgacctga gtagtcgaca cgtttaccta gcaagttttg
    24301 acggaaacga ccttgtttcc ctttcaacat atgagaaaga gatttcaatg ggcggttacc
    24361 tggtccagta actggacgtc cgcgacgacc gttatcgatc aatgcatcta ctgcttcttg
    24421 cagcatacgt ttttcatttt gaacgatgat tccaggtgca ttcaagtcta acaaacgttt
    24481 caaacggtta ttacggttga ttacacgacg gtaaagatca ttcaagtcac ttgttgcaaa
    24541 acgtccacct tctaattgaa ccattgggcg taaatctggt ggaataacag ggataacgtc
    24601 cataaccatc cagcttggtt gatttcctga agcgcggaat gcttctaaaa tatccaaacg
    24661 gcggattgca cgtgtacgtt tttgtccttg tgcagatttc aattcttctt tcaattcggc
    24721 tgcttctgca tctagatcaa cattatcaag taattgttta atcgcttctg cacccatagc
    24781 agcttggaat tcttgtccat attgttcacg tttttcgcga tattcgcgtt ctgtcaacaa
    24841 ttgttttttc tctaaattcg tatttcctgg ttcgatgact acatatgaag caaaataaat
    24901 gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga cccatacgtg aaggaatccc
    24961 tttaaagtac cagatatgtg aaacaggagc tgctaattca atatgtccca tgcgttcacg
    25021 gcgaactttc gaacgagtaa cttccactcc gcatcgatca caaacgattc ctttataacg
    25081 gatacgtttg tattttccgc aggcacattc ccagtctttt gtaggaccaa aaatccgctc
    25141 acagaacaac ccttcgcgtt caggttttaa ggtacgatag ttaatcgtct caggtttttt
    25201 tacttcaccg taagaccagc ttctgatttt ttcgggagaa gccaaaccta tttgcatact
    25261 ttcgaattta tttacatcga tcaaaagggg ttccctccat ttcatttaat ggcaaaccgc
    25321 aagacggctg atcttcgacc gccttgcagc tcatagaccg gattagtcta aattatcttc
    25381 tgcggtttca aagttttgga tgacatcgtc tttttcatct tccacttgtt cagcagcttt
    25441 cttttctaat tctttggcag tttgctgttc ggcaaatttt gtcaaagcat caacagtgat
    25501 caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc tctgtttctt cgatatccaa
    25561 gacacgcatg tccagaccta gtgattgcaa ttctttcacc aatacgcgga atgattccgg
    25621 tacacctggt tttggaattg gttcaccctt gacgattgct tcgtatgttt tcacacgtcc
    25681 gactacgtca tctgatttgt atgtcaagat ttcttgtaaa gtataagccg caccgtaagc
    25741 ttccagtgcc catacttcca tttcaccaaa acgttgtcca ccaaattgag ctttacctcc
    25801 caatggttgt tgtgtaacca atgagtaagg tccgattgaa cgtgcatgca atttgtcatc
    25861 gaccatgtga gcaagtttga tcatgtacat cacaccgaca gacacacgtc catcaaatgg
    25921 ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg ctggccatac cggcttcacg
    25981 aactgtttcc catacgtctt catcacttgc accatcaaat actggcgttg ctacgtggat
    26041 acctaactga cgtgcagcca tacccaagtg taattccaat acttgcccga tgttcatacg
    26101 tgaaggcacc cctaaaggat tcagcatgat atcgattggt gttccatcag gtaggaatgg
    26161 catatcttct tccggcataa tacgggatac aaccccttta tttccgtgac gaccggccat
    26221 tttatcccct tcatggattt tacgtttttg aacgatataa acacgaacta acatgtttac
    26281 gcctggtgac aattcatctc cagcttcacg agtaaagatt ttcacatcgt gaacgatacc
    26341 gccgccgcca tgtggtacac gtaatgatgt atcgcggact tcacgagctt tttcgccaaa
    26401 gatcgcatgc aatagacgtt cttctgcaga taattctgtt accccttttg gcgtgacttt
    26461 ccctacaagc aaatcgccat cttggacttc tgcaccaata cggatgatac ccatttcgtc
    26521 taaatctttt aatgcgtctt ccccgacatt agggatttcg cgtgtgattt cttcaggtcc
    26581 taattttgta tcgcgggctt ctgattcata ttcttcaata tggatagaag tgtatacgtc
    26641 atcttttacc aaacgacggc tcatgatgat cgcatcttca tagttgtacc cttcccaagt
    26701 catgaaacca actaaaacgt tttggcctag agccatttcg ccttgttcca tagatggtcc
    26761 gtctgccaga gtatcccctt tttcgacttt ctcacccaaa tgaacgattg gacgttggtt
    26821 gtagcttgtt ccggagtttg aacgacggaa ttttgttaca tcgtatttat ctaatgcacc
    26881 gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat tcaacgacac cgtcatgttt
    26941 acataacaaa gcagctcctg agtcatgcgc tgatttgtat tccataccag taccaaccca
    27001 tggtgcttga ggattgatca acggcactgc ttgacgctgc atgttggcac ccatcaaggc
    27061 acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg caactacttg
    27121 tttaggtgat acgtccatgt agtctacttt atcaatagat acttctaagt tttcactttg
    27181 agcacgagcc ataacaacgt cttgagcaaa tgttccatct tcattcaatg ggctgtttgc
    27241 ttgggctacg atgtaatggt cttcgatatc agctgtcaag tagtcgattt ggtcagtaac
    27301 acgacctgtt tcacggtcta cacgacgata aggtgtttcg ataaatccga atttatttac
    27361 tttcgcataa ctggacaaac tattgatcaa cccgatgttt gggccttcag gagtttcgat
    27421 cggacacata cggccatagt gggagtagtg aacgtcacga acttcataac cggcgcggtc
    27481 acgagtcaat ccgccaggtc ctaaggctga aagacgacgt ttgtgtgtca attcgccaag
    27541 agggtttgtt tgatccatga actgtgacaa ctgagaagaa ccaaagaatt ctttgatact
    27601 tgccacaact ggacggatat tgatcaattg ttgaggtgtc aatgtttcag tatcttggat
    27661 cgacattctt tcacgaacca cacgttccat acgtgctagc ccgatacgga attggttttg
    27721 taaaagttca ccgactgaac ggatacgacg atttcctaag tggtcgatat catcgacatt
    27781 gccgatacct tccatcaagt tcaagaaata gctcattgaa gcaatgatgt cggctggacg
    27841 aaccgttttt acagctgctt ctggatagcc gtttccgatc acgtttactt cacgttcagg
    27901 gtctcttggt gaaaatactt tgatgacttg gacagtcatt ggatctgtga ccacaccgtc
    27961 ttctgatgga tagtaagtca ctgaatttag gccattatca atgaaaggag ctagtgtttc
    28021 catgacttgg tgagtcagaa ctgttccttt ttcaacgatg atctcgcctg tttctggatc
    28081 aactaatgtt tcagctaatg tcagattcaa tagacgtgtt ttcaaatcta attttttgtt
    28141 tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt ggatcgaaga aacgagcatt
    28201 cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct ggacgcaaac gttcgtaaac
    28261 gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt ttatgcaagt ctttttcgac
    28321 tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag atcgtatcat cggaaccaaa
    28381 tcctaacgca cgaactaata cggttaaagg aatcttacgt gtacggtcga tacgtacata
    28441 agagatgtct tttgcatcag tttccatttc tagccaagct ccacggttag ggataacagt
    28501 agaaccgaat ccttcttttc cgtttttgtc gacttttcca tggaaataga cacctggtga
    28561 acggactaac tgagaaacga ttactcgctc tgccccgttg atgatgaatg ttccttgttc
    28621 tgtcattaat gggaaatcac cgaagaatac ttcttgtgct ttgatttcgc cagtctcgcg
    28681 gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag tttgcatcat gcgcacgagc
    28741 ttctgctact gtatactttg gttctttcaa ttcataatct acaaattcca aagatagatt
    28801 gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt tctctaagtc cctcatctaa
    28861 gaaccattgg taagagtctg tttgaatttc gatcaaattt ggtaattcca acacttcact
    28921 gattcttgcg aaacttctac gttcgcgatg ttttccgtat tttactacgt gtccagccaa
    28981 gctcttcacc cctctaaaat gtcattcaaa aagactaccc gatcaattgt tacaataata
    29041 tttcaaatat tatttttagg taacaacaga cattttttgc ggcttttagg caaaaaaaaa
    29101 ccaaaaatag aacattctct tgaaacctta cttcgtgagc ttctactttt gtttccttat
    29161 attaaagccg aaacggacaa tatttcgttt ctgccttttc ttcatcagat agtttttgca
    29221 acttcatata ctacacttat tttctataaa agtcaacact tcctggcgtt tcttctgctt
    29281 tttcgcaaca ttttcttaat gttttcaatt ttatgttttc aattatctga caattcttaa
    29341 ttgacagacc tttttatctc ggttatactt tagaaaattc attttgtgga ggaacttcta
    29401 tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa taacttttac tttagctact
    29461 ttagataggt ttgtattcat catgatggat acaaacgtta aacgacagtt tgtatctatg
    29521 atggctaaag aactttgtat tgcagcaaaa agccacgtag acaaaatgct aagtggctga
    29581 gcagtgaaaa tacaaagtaa aagtatcaag cattctactt tttcaattta ttttccgact
    29641 tttcaatcca tttggacatt ttgtctgaat ggattttttg tttcccaaaa ttaaggagga
    29701 aaaagaaatg aaaaaaaata taatcatcgg attaggcgct gccctgctac tagctttagg
    29761 aggttgcgca caaaaagaca attccgcaga ggcatcagat ggacaaaaaa caattggcgt
    29821 attgcaactt gtacaacata actcgttaga tgctgcctat aaaggattca aagaaggatt
    29881 agcagaagaa gggtataaag aaggcgataa tctaacaatc gattatcaaa atgcccaaaa
    29941 caatcaagac aacctgaaaa gtatgagtga gaaactcgtc aaagaagatc ctgatttgct
    30001 acttggaatc gccactccag cagcacaatc tttattaaat gaaacaacca ctatcccgat
    30061 gactgtcaca gcggtcacag acttggaaca agcccattta gtcacatcca atgaaaaacc
    30121 tggcggcaat gtgactggca cgacagatat ggtgccaatc gaaaaacaaa tcggcttact
    30181 gttaaatatc gtgccagacg ccaaaacaat cggcatcatg tataacaacg gtgaagcaaa
    30241 ctctaagatc caagctgatt tggcagaaaa agaattgaaa aaagcgggcg tcaaagtcaa
    30301 agtactgaca gcaaattcca caaatgatgt ccaacaagtg acgaaaagtc tagctaaaga
    30361 tgtagatgga atctatattc ctactgataa cacgttcgca agtgcggcaa gtgttgtcgg
    30421 tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc gcagttgatc aagtcaaaga
    30481 cggcggtcta gcaacagtag gaatcgacta cgaaagcttg ggcaaacaaa cagggatcat
    30541 ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt cctgtcgaaa cagcgaatga
    30601 tttggaactg tatgtcaata aagacatggc caaagcatta ggcatcaatc cagacagcat
    30661 caaagaagct gaataaaaca caggaggatt ctcatgacaa atttgctctc tcttttctta
    30721 tcatctgcat cgcaaggggt cttatgggcc ctacttgcga ttggtgtata cgtcactttc
    30781 cgtatcttgg acattgccga cttgactgct gaaggaagct ttcctttagg tgcagggatc
    30841 gcggcagtaa gtattacaaa tggctatcat ccattgacag cttgtcttct aggcttttta
    30901 gggggtgcgg cagcagggct tgtttccgga ctgcttcaca caaaattgaa aattcccgcc
    30961 cttcttgcag ggatcatcac catgactggt ttatattctg tcacatcccg tgtgatgggt
    31021 gcgccgaaca tctctttatt gggtcagcca acgatctttc attgggtcga gtcattcggc
    31081 ataacaaaag acaacgctgt actgatcgtc ggtctgcttt ttgctttgat cgttgtatgt
    31141 ttacttgttt tgttcttacg tacagaaaca ggacttgcta ttcgtgcaac tggcgataat
    31201 ctggcaatga gcgaagcaaa cgggatcaac acagataata tgaagatcat cggttatatg
    31261 atttctaatg gatgcattgc tctttctggc tccttacttg cgcaaaacaa cggctttgct
    31321 gatttaaatt ctggtattgg aacgatcgta attggacttg cttctattat catcgcagaa
    31381 gttttgttac gtaaccagcc actatttctc cgtctcttga ctgtcgtttt aggtgcggtc
    31441 atttatcgtt ttattttagc gttagtcttc gaactgaatg ttgaaccaag tgattcgaaa
    31501 cttgcttctg ctttcgtgct agtgatctgt ctttctttcc cgcagatcca gcaaaaattc
    31561 catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa tgacgtctta acattggaaa
    31621 atctccatca tacctttgaa aaaggaacga tcaacgaaaa tcatgtcctg aaaggcatta
    31681 atctttcctt agatcccggc gacttcgtga cgatcatcgg tggaaatggg gctggtaaat
    31741 ctactttgct gaacagcatc gccggtacat tttctgtcga tcagggtcaa attttattga
    31801 atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc gaaatccatc agtcgcgtat
    31861 tccaagatcc taaactaggg acagccgttc gtttaacggt agaagaaaat cttgctcttg
    31921 ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt caaaccacaa gaccgaacat
    31981 ttttcaaaga ccagctggtt cggctaaatt tggggttgga aaatcgttta tcctcagaaa
    32041 tcggtttgct gtctggagga caacgtcaag ctattacgtt attgatggcc acattacagc
    32101 gtccagaact gatcttatta gatgaacaca ctgcagcgct tgaccctgct acttccaaaa
    32161 cggtgatgga attgacagaa aagctgatca ctgagcagaa tctcactgct tttatggtca
    32221 ctcatgacat ggaagacgcg atccgctatg ggagtcgact gatcatgctg catcaaggaa
    32281 ggatcgtcgt agatatccag caagaggaaa aacagcagct cacagtgccc caattattag
    32341 cgttgttcaa acaaaacagc ggcacggcat taaaagacga tcaagtactt ttatcttcat
    32401 aatcagaaag aggatgggac aaaaaatgaa cgcccaccct cttctttttt ctctttcctt
    32461 ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga aaactatttt gttctctcct
    32521 tcttcctgat agaatggatg ggaaaggagc ttgatgccat gacaacgaaa gacaaggtac
    32581 ttcaattatt gaaaaagaca ccagattttc tttccggaga aaagttggca cagcaactgg
    32641 aagtttcccg gacaagtatt tggaaagcca tcaaagaatt ggaaaaggca ggctatcgtt
    32701 ttgagcacgg gcctacaggg tatcgttacc tgccctctga cgtactagat gcaaaagaaa
    32761 tccagcaaga gctacggtcg tttattcctg atttgaaagt acaaacgatg ttgacttctg
    32821 aatctacgat gaaagatgcc aaactggcag cagctcaagg agattctgtt tcgaagttat
    32881 ttgttgctga tacacaagaa caagctcgtg gacgttttgg acggcctttt ttcgctgaac
    32941 ctggacgagg aatctacatg agtctcttgc tccatccaga caaacggttt gatgaattgc
    33001 ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc cattgaatct gtaaccggtc
    33061 gttctgcttc gatcaaatgg gtcaatgata tctacatgga tggaaaaaaa gtctgtggga
    33121 ttttatctga agcagtcagt gatatggaaa gcggcaggat cagtcatatc atcattggga
    33181 tcgggcttaa tttttctgtt cctcaaaatc attttccagc tgatctccaa gaaaaagcca
    33241 tctctgtctt tcccgacgga caagctagtg tcacaaggaa tcagctaatc agcaaaatct
    33301 ggcaagaatt gttcacttat ctttctcacc cagaaaaagc gttggacttc tataaagaaa
    33361 aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa aggaacgact tatgtcggtc
    33421 ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca aacaaatgaa cagaagatga
    33481 gtttgtcttc tggcgaaatc agtctcacat ctatccgtac gcaataatta tcagatttca
    33541 caaaaggaca cctgatctca tacagtgtcc ttttttctga attctcttca aaagactctc
    33601 cttattctat cagctgacag tttctctatc ctctagaaaa aggtattcta aaaatatcta
    33661 taaagcatgg tacactttct ttaaatgaat caatgcaaaa aacaagagag tcatcagttt
    33721 acacgatcaa aagagatagc aggccgcttc ctttttcaat cttatagata gaccatgggt
    33781 aacgataaaa acaaaaaaga acttgcgact tattttgccg taagttcttt tttagctagt
    33841 gccttaatct cttaatccca acaaacgtct cgcatagatc acctgaccag agtgcatagc
    33901 agcatcatca ataatagaaa cgagacgcat tcctcgtgtg actggtggtg tccagttctc
    33961 gtcaattact tcatctagct cggaaggttc cagccttctt aagtaagaaa tagcaaaatc
    34021 agcagctcct cgcaagtatc ctagcagatc ttctatttga ttagcttgga tctgctttgc
    34081 ttgttccaga ctatgcttcc aatcttgttc gttatctgct atcgtcatcg gaaaccggct
    34141 ttcccagtct tgactatgcc aaattggaga agttcctgct aaatcagcaa tctggaaatc
    34201 taattctcga gcggtatgcc aagccagcca agtcattgat ttgatctgcg gggctctatc
    34261 ttccactgga aaacgattgg cctcctcaat agagacgcct tcaaacaaac gttcaaaccg
    34321 atcgtatgcc cgatccacac tctcgcatag catatctaaa taatccattt attttcctcc
    34381 tttttattta tcctacttac tttttcctaa ttctaggata cctacttata tgttactaca
    34441 cacccttatt ttttacactt taacagtcac catcatcaat agtttggaga ttgaaagaaa
    34501 aagatagtgt cgaactatca attgaacaag aagcaacaat atgaacgttt cattaatatt
    34561 ctttaaataa acaatgattt ttcaaacgaa cagtttaaga ctaggagaaa aagagtataa
    34621 taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa aaaagggcaa gtttactagt
    34681 cctagttgct ttgttgttca atatcttttc gtatggtgtg gccgtttcag cggaaacata
    34741 cattcctaaa gaccctggga atatttataa tgatctaact ggtaactatg gcttgttagg
    34801 aattgctagt caattccacg tatttgctaa aaataagaca actgtgaatg cacatacaga
    34861 cggaaatata gcaacacatg aacttgatgc aaaaaataat tttggtacag agcttcatga
    34921 aggtttattg aaccaagaaa taaattatat acaaaaaact gattctttcg ctaattcttc
    34981 aggcatacct acaggtagca caagaatgaa taaatttgtc gttggcagta acgtggatgt
    35041 agcacttcaa gatggtcatc ctacagtcaa tggatccagg cttgatcact taactccaga
    35101 tgatttttat aaagatcgtg ctgggcatga atatattgat ttcgagcagg aatttgctaa
    35161 attgaatgta gcagcaaatg atcttgcaac gatcactcca gctaaaacat atactgctgc
    35221 agattttcca gacatgaaca atcggacaat cgatttaact gatttatcag ataccgggtt
    35281 tttattggta aatatcgatg cagaagtgtt aacgatgaat acgccacttc aaatcattaa
    35341 tccaaatgat caagtagttg tatttaatgt catcaacagt tcttctgcat tgaacgtaca
    35401 gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca gaagattttt cggatgcgaa
    35461 tatctcttgg aattttggaa atgagatgac tgatttgaca atcagtgctc cttttcaagg
    35521 aacaatcctt gcgcctaatg ctactatccg cattactcaa aaccaagacg gaacgattat
    35581 aggaacaaat gtgattttag atgcagctac caatcgttgg gatcctaacg aaatatttat
    35641 cagcgacaat ggtacagata cgacagacac aagcgacagt acagatacat ctaccacaag
    35701 tgatagctca gattcatca
//
LOCUS       DACBZK010000022        35019 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.022, whole genome shotgun sequence.
ACCESSION   DACBZK010000022 DACBZK010000000
VERSION     DACBZK010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35019
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.022"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(56..2653)
                     /gene="adhE"
                     /locus_tag="IVD66_001146"
                     /gene_synonym="adhC"
     CDS             complement(56..2653)
                     /gene="adhE"
                     /locus_tag="IVD66_001146"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HAP6145382.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(2958..3338)
                     /gene="yajC"
                     /locus_tag="IVD66_001147"
     CDS             complement(2958..3338)
                     /gene="yajC"
                     /locus_tag="IVD66_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HAP6145383.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(3435..4580)
                     /gene="tgt"
                     /locus_tag="IVD66_001148"
     CDS             complement(3435..4580)
                     /gene="tgt"
                     /locus_tag="IVD66_001148"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HAP6145384.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            4798..5496
                     /locus_tag="IVD66_001149"
     CDS             4798..5496
                     /locus_tag="IVD66_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAP6145385.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(5664..8303)
                     /locus_tag="IVD66_001150"
     CDS             complement(5664..8303)
                     /locus_tag="IVD66_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP6145386.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(8922..9953)
                     /gene="queA"
                     /locus_tag="IVD66_001151"
     CDS             complement(8922..9953)
                     /gene="queA"
                     /locus_tag="IVD66_001151"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HAP6145387.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            10146..11321
                     /locus_tag="IVD66_001152"
     CDS             10146..11321
                     /locus_tag="IVD66_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP6145388.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            11325..11966
                     /locus_tag="IVD66_001153"
     CDS             11325..11966
                     /locus_tag="IVD66_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6145389.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            11963..12880
                     /locus_tag="IVD66_001154"
     CDS             11963..12880
                     /locus_tag="IVD66_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6145390.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            12877..13548
                     /locus_tag="IVD66_001155"
     CDS             12877..13548
                     /locus_tag="IVD66_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6145391.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(14089..14577)
                     /locus_tag="IVD66_001156"
     CDS             complement(14089..14577)
                     /locus_tag="IVD66_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HAP6145392.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(14778..15044)
                     /locus_tag="IVD66_001157"
     CDS             complement(14778..15044)
                     /locus_tag="IVD66_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAP6145393.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(15044..15307)
                     /locus_tag="IVD66_001158"
     CDS             complement(15044..15307)
                     /locus_tag="IVD66_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP6145394.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            complement(15300..15572)
                     /locus_tag="IVD66_001159"
     CDS             complement(15300..15572)
                     /locus_tag="IVD66_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145395.1"
                     /translation="MYWCCCIDSQALDSTFAKDDTLLPITLRLATASRKGVRSERGQR
                     SSLKRGLFLYVKKRKSLLNLSALLYFFDVLNQVRYNYIRKRRRDNG"
     gene            15783..15968
                     /locus_tag="IVD66_001160"
     CDS             15783..15968
                     /locus_tag="IVD66_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP6145396.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(16110..17933)
                     /locus_tag="IVD66_001161"
     CDS             complement(16110..17933)
                     /locus_tag="IVD66_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HAP6145397.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(18531..21236)
                     /locus_tag="IVD66_001162"
     CDS             complement(18531..21236)
                     /locus_tag="IVD66_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HAP6145398.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(21542..22489)
                     /locus_tag="IVD66_001163"
     CDS             complement(21542..22489)
                     /locus_tag="IVD66_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HAP6145399.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            22679..22948
                     /gene="rpsN"
                     /locus_tag="IVD66_001164"
     CDS             22679..22948
                     /gene="rpsN"
                     /locus_tag="IVD66_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAP6145400.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(23124..23486)
                     /locus_tag="IVD66_001165"
     CDS             complement(23124..23486)
                     /locus_tag="IVD66_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP6145401.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(23497..24618)
                     /locus_tag="IVD66_001166"
     CDS             complement(23497..24618)
                     /locus_tag="IVD66_001166"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HAP6145402.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(24634..24984)
                     /locus_tag="IVD66_001167"
     CDS             complement(24634..24984)
                     /locus_tag="IVD66_001167"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HAP6145403.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(25114..26625)
                     /locus_tag="IVD66_001168"
     CDS             complement(25114..26625)
                     /locus_tag="IVD66_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP6145404.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(26947..28299)
                     /locus_tag="IVD66_001169"
     CDS             complement(26947..28299)
                     /locus_tag="IVD66_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HAP6145405.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(28452..29528)
                     /locus_tag="IVD66_001170"
     CDS             complement(28452..29528)
                     /locus_tag="IVD66_001170"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HAP6145406.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            29724..31469
                     /locus_tag="IVD66_001171"
     CDS             29724..31469
                     /locus_tag="IVD66_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HAP6145407.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(31749..32186)
                     /locus_tag="IVD66_001172"
     CDS             complement(31749..32186)
                     /locus_tag="IVD66_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HAP6145408.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(32170..33543)
                     /locus_tag="IVD66_001173"
     CDS             complement(32170..33543)
                     /locus_tag="IVD66_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145409.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(33865..34353)
                     /locus_tag="IVD66_001174"
     CDS             complement(33865..34353)
                     /locus_tag="IVD66_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6145410.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(34375..34977)
                     /locus_tag="IVD66_001175"
     CDS             complement(34375..34977)
                     /locus_tag="IVD66_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP6145411.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         9919 a         7476 c         6466 g        11158 t
ORIGIN      
        1 ttttccaagt tctttttcat ctattttctt atcttttttc tacgctttct tttgcttatc
       61 cgttgtaagc atcaatgatg atctgtttca attcagagat caatggttct ttcggattag
      121 ctgtcgtaca ttggtcttcg taagctaatt cagccatacg gtctacggtt gtatctagtg
      181 tttcttgtgt gactccttga gcttttagac tcatgttgat gccgacagat tttcctaatt
      241 cataaacagc cgttgctaaa gcttcgacta attcctctgt tgtttcgcct ttcagaccta
      301 agaattttgc gatatctgcg taatctgtat ctgcacggaa atagtcatat ttagggaaca
      361 tcgcatgttt ttgtggatct tttgcattat agcggataat atgcggtaaa agaatcgcat
      421 ttgtccgtcc atgagggatc ccgtattccc cgccgatttt atgtgcgact gagtgacaaa
      481 tacctaggaa tgcgttagca aacgccatac cagccattgt agaagcgttg tgcatttttt
      541 cacgtgattc catatcaggt gtttttactg atttttctaa atagtcaaag actaacttga
      601 ttgcttgtag gctcaatcca cgtgtataat ctgaagccat gactgaaaca taggattcga
      661 ttgcatgtgt taacacatcc atcccggtat ctgctgtgac agatgctgga actgacatga
      721 cgaattgagg atcgacgatt gcgacatctg gcgtcaatgc ataatctgct aacggatatt
      781 tcacatgtgt ttcactgtca gtgatgaccg caaatggcgt tacttcagaa ccagtccctg
      841 atgttgtcgg gatacatacg aattgtgttt tttctggttt gtcgatctta tatgtccgtt
      901 tacggatatc caagaatttt tgttttgcac caaagaaaga tgtgtctggg tgttcataga
      961 acatccacat tcccttagct gcgtccattg cagaaccgcc tccaagagcg attactgtat
     1021 ctggcttgaa gtctgccatc agtttcgttc ctgcgtatac ggtatttgtc gatgggttcg
     1081 gttcaacatc tgagaagact tcgatcttca catcattttt acgtcgtgcc aatacttcac
     1141 gaactgtatc gcagtaaccg aattggacca taccagggtc acaaacgatc atgacacgtt
     1201 caacgttttc cattttctct aagtacaata gagagttctt ttcaaagaag atttttggcg
     1261 gtaatttgaa ccattgcatg ttatttctcc gtttcgctac agttttgaca ttgattaagt
     1321 ttacagcaga gacgttacga gaaacagagt tcttaccata agaaccgcat cccaaagtca
     1381 atgacggaat catttcgtta tagatatcac cgatgccgcc ttctgcagat ggtgtattca
     1441 ctaaaatacg acaagctttc attcgaagac cgaatttgac atgcaactct tcgttttctg
     1501 aatggataac tgctgtatgt cctaatcctc caagattcaa cataccttca cacaaatcaa
     1561 acgcatggtc cgtgttgtta gctttgatca tggcaagaac tggagaaagt ttttctcttg
     1621 atagcggata atctgggcct acgccttcca attcagcaat cagcattttc gttccttttg
     1681 gtacactgat tcctgccaat tttgcgattt ccatcgcaga atgtccaacg attgatggat
     1741 tgaccgcata ttttccttcg ttcatcactg catcttctaa tttttgcaat tcatctggtt
     1801 ttacgatata aacttggtgt gcttggaatt ctgcttttac tgctgcatag atttctttat
     1861 ccacgatcac agcttgttca gaagcacaaa tcattccatt atcaaatgtt ttcgaaacga
     1921 tcaaatcgtt cactgcacgt ttaatttttg ctgttttttc aatataagct ggtacgttac
     1981 ctggacctac acctaaagct ggttttcctg tagagtaagc agacttgacc attccagctc
     2041 cacctgtcgc taagacgatc gcgatacctg gatggttcat tagcatagaa gtcgcttcga
     2101 tcgaaggatg ttcgatccat tggatacaat tttcaggagc tccggcagcg atagcagcat
     2161 cacgtaccac tcgtgctgct tctgcagaag atttttgggc acttggatgg aaagcaaaaa
     2221 cgattggatt tcttgttttc aacgcgatca ttgatttgaa aatcgttgtg gaagtcggat
     2281 tcgttgttgg agttactccg caaaccacac cgactggttc agcaatttca atcaaccctt
     2341 tttggacatc ttcattgatc acaccaactg ttttatcatg tttgatatta tgccaaatat
     2401 attcggacgc atacatattt ttgattgctt tatcttcgta aacaccgcgg cctgtttcct
     2461 ctacagccat cttcgctaat ggcatatgtt gatccaaagc tgccattgcc atttcatgca
     2521 cgatatggtc tactttttct tgatcaaagc tttccatttc tttcaatgct gcatttgctt
     2581 tttctgccaa atcatcaatc attgcttgta cgtcaattgt cttcgttttt tctttttcta
     2641 ttactttagc catcattatc ctcctaatgg gtcatggtta tttgttaaat aattcacatg
     2701 tatatcatac aatatttatt tttctatgta aacacttttt tgtgattttt ttcacagtta
     2761 tttttaaata taaaattgct ttatttacag gtgtttgtat agaaaaatat ataaagttat
     2821 ttattattat ttatatgaca cacccgatta ttcaatattg agcaatatat cccatgctct
     2881 tatctctttc ttttttgaat aaaaaatgag gtaggacatc tttctgccct acctcgtctt
     2941 taaataagct ttgatactta tttttcttcc ttctcttctg tctcttccag cgtttctgtt
     3001 gtttcagttt ttacttcaac tgtctcagct ggttcttctg ttgtttcaac agtagtcgtt
     3061 gcatcatttg ttacgacagt ccctggtttg accgttttga ttgctgcacg atcgtactca
     3121 aggaagatcc cttcgcagtc taaaacaact gtccgtttgt cattgtcgat ttctgaaaca
     3181 actccatgta atccgccgat cgttacgact gaatcacctg gtttcatgct atctaacaag
     3241 ttttgacgtt cttgctgttg tttcttttgc gaacgtgaca taaaaaacca cattgctaat
     3301 agcgcgataa acatcacaag cattggtaat gttcccattt ttttcacctc actaattctg
     3361 tatctacaaa aaacacttta gcagaaaaat gctgataaca ctagtttttt acttaatttt
     3421 taaaagattt tcctttagaa gctttttgcg ttttctttat tgaacccgta ttcttcaaaa
     3481 aaggcttctc taaattcaag caaattatca tccatgattg cttgacgtac ttgtttcatt
     3541 agattcaaca agaagtataa attgtggtaa gaagtcaaac gaatcccaaa tgtttcatca
     3601 catttgatca aatggcggat ataggcacgt gtatagtttt tacatgtata acaatcacat
     3661 ttctcatcaa ttggacggaa atcatgggca tatttcgcat ttttcactac tagacggcct
     3721 tgagaagtca tacatgtgcc atttcgagcg attcgagtag gcaagacaca gtcaaacatg
     3781 tctactccac ggataacacc atcgatcaat gaatcagcag caccgacacc catcaagtaa
     3841 cgtggtttgt tttcggggat caacggtgta gtgaattcta atacacgatt catttctgat
     3901 ttaggttccc cgacagataa cccgccgatt gagtaaccag ggaaatccat cccgactaga
     3961 tctttcgcgc tttgacgacg aagatcttca aaccctgctc cttggatgat tccaaataat
     4021 ccttgacggt ctggattagc atgagctttc aatcctcgtt ctgcccatcg agacgtacgt
     4081 tctactgatt ttttcacgta gtcgtaactt tcatcgaatg gtggacattc gtcaaaactc
     4141 atcatgatat cagagcccaa tttattttgg atgttgattg ctttttctgg tgataaaaac
     4201 atacgcgaac cgttcaagtg atttttgaaa tgcacgcctt cttcttcgat attccgcata
     4261 tcacttaatg aaaaaacttg aaagccgcct gaatctgtta aaatcggttg atcccagttc
     4321 ataaatttat gcagtccgcc agcttcttct actaagtctt caccagggcg tagccataaa
     4381 tgatatgtat tacttaaaat aacgccagca cccatttctt tcaactcttc tggggacatt
     4441 gtttttactg tagctaatgt tcctactggc atgaacattg gtgtggggaa agttccgtgt
     4501 ggcgtgatca attcccctaa acgcgcgcca gtatgttttt ctttcttgat taaacgatag
     4561 cgaatggcag gttgcgtcat tcatttccct actttctata taaaatatct tgacaactcc
     4621 caccatcata atcgtttcaa gtgctttttg caagttccct cggcttcctt ctactttatt
     4681 taatattctt ttttttatcc tttttttatg aataacaaaa aaaagaaaaa cattatgaca
     4741 gaaatatttt ttgatacatg gtatattggt gttattaaag aaaaggaggg aaaaatcatg
     4801 caatcttctg cagaattaaa acgccaagca aaagagagtc taaaaggacg ttggggacaa
     4861 gctgttttac taaatctaat ccctacattg attggtattg ctactattct tcttattatg
     4921 attcctatta tcttgtttgc caccaccata tatgatggat cagcgagcgt ctcagaagcg
     4981 acaacttcag gaggcggtag ttcaggaggc ggtggcggaa ttatttccag catcattagc
     5041 gctttgttca tgagcggtat ttcttggact tatcttgata ttttacgtgg acaaaaagat
     5101 cagatcgaac cattcaaaga tgcatttcgt ggattcaaag gtttgtttat cggcggagtg
     5161 atcagcttag ctgtgctgat ctcgatcttt acaacattat ggggtttgct attagttatt
     5221 cctggaatca ttaaaagcta ttcttattct caaagctatt ttatttacta cgatatcgtc
     5281 caagaaacag gacaaacacc taaagtactg gatacgatca ctgcaagtcg aaaattgatg
     5341 gatggttata aaggacaact tttctggtta gatctttcat ttatcggctg gcatatctta
     5401 gcattagcaa ctgctggtat tggttatcta tggctcagcc catacatttc tgcaacaaaa
     5461 gcagcatttt atgaacaatt gccaaaagat atttaaaaga gagtgtgact tgtgaccgag
     5521 ggggtggcag gagaacaccg tttatcgaga ggcagtaaaa gaaacattca gcccattagc
     5581 aaaaaggagg tgtgacaaca ttcatgtcac acctcctttt tgtatagttc cagtaaaaag
     5641 aaaatcaact tagaaacagt taatcattcc tcttcttctg cttccggtaa tcgatggaac
     5701 ttgatcagtt cattcaccgc gattggtacg atagataaaa tccctaccaa gaaccagtga
     5761 ttcaaactga tgtgtactag gccgaatagt tcttgcgtaa atggcagcaa agcaacagcc
     5821 gttgtaatag ctaatgccag taacgccatt tctaccaaag ctttattggt cgctaaattg
     5881 actttgaaga tcgattggct gctgcgtaca ttgaacacat gcagaatcga tgaataagct
     5941 aagatcaaga atgcaacagt ttgaccgaca tgctgacttg cgtctaccca tgggctgata
     6001 gtatcgacat aactacctaa ataataacca aacaaggtta cgatggtgaa gacccctgca
     6061 tttatggcaa ttttttgcaa taaacctcga gcaaagatcc cttcattttt cggaatgggt
     6121 ggctgatcca tgatgccgtg ttccgctggc tctcttccta aagcaaatcc tggaagtcca
     6181 tcagcaacta cattgacaaa cagtagttgc acagctgtaa atggtgctcc ccatcctaac
     6241 agcatcgcaa tcaaaacaat aaagatctcc gaaatattac agcttagcaa aaagttgata
     6301 gctttacgaa tattctgata aaccgaacgt ccttgactga cagcgtctac gatcgtcgca
     6361 aagttgtcat ccgtcaaaat catatctgcg gcactttgcg ccacatctgt tcctgtgatc
     6421 cccatggcac acccaacgtt acttgctttc aacgctggtg catcattcac accatcccca
     6481 gtcatcgcta cgactgcacc cgtacgttgc caagatttga cgatccggat cttgtcttct
     6541 ggcgttaccc gagcatagac agagagagct ttgacacgcg catctaattc ttcgtctgat
     6601 aattgatgca gttctgatcc tgaaagtgct tctgacggat cattcaagat acctaattct
     6661 ttcgctatgg cactggcagt caccacatga tctccagtga tcatgactgt tttgatgcca
     6721 gcctttttcg ctcgcttgat tgctccttta ctttctggac gtggtggatc gatcattccg
     6781 atcagaccaa tcaaacgtaa gtctttttcc agtgcttcag aagaaatatc ttgcggttct
     6841 tcgtcataag tagcataacc aacagcaatc actctcagtg cccgtttacc aaagcgatca
     6901 ttaacgatcg ccgcttgttc tacatcgcct gaactaaagc gcggagcaag aacatcgaat
     6961 gctcctttgg tgattgagat gtatttttcg cccatttggt gaactgttgt catcattttt
     7021 cgttcagaat caaaaggaag ctcgtttact cgtggatatt tttcttctaa ttctgccttt
     7081 gtatgataat tctcttcaac agcccttacg atggctactt ctgttggatt acctttgata
     7141 acaaggtcgt catcttcttg ctcgaccgtc acatctgtac atagtgcagc cattttcaat
     7201 atttccatcg cgctgttcgt cattgaatct tcgatattcg ttacttcatc ttctttgctc
     7261 catacccggc ggacgcgcat ttcattttgt gtcagcgttc ctgttttgtc tgagcagata
     7321 acattagcgg ttcctagcgt ttcaactgct ggcaactgtc ggatgatcgc atgtttcctc
     7381 gccatcttct gcacaccgta tgcaagtgtc aacgtaacaa taacagtcaa ggtttccggt
     7441 acagctgcaa cagccaagga aatcgaagtc atgaacatct caaggagtgg ttctccttgc
     7501 agttcaccaa tcacaaatac taaagccgca gccgctaaag cgatcatact gattcgtttg
     7561 cctagctgat tcaatcggac ctgtaaaggt gttttttgca tagtattttc gttcaaaaga
     7621 tccgcgatct tacccatttc tgtagccatg ccaatggcag tgacgatcgc tttcccacga
     7681 cctgcagcaa ccgtacatcc tttaaatacc atattaagtt ggtcacctaa tgactcatct
     7741 tcttcagcaa taaatgctgc atctttttca actgcttcac tttctccagt caacgccgat
     7801 tcttctacac gtaattgtga tgcttcgatc aaacgggcat cggcagaaat agcatcaccg
     7861 gactctaaaa caagaatatc acccactacc agttgctctg actcaacagt ggtcactttg
     7921 ccgtctcgta tgacagttgc cgtttgttta ttcatatctt gcaaggattc cagtgctttt
     7981 tctgcgtttc cttcttggac aatcgccaat accgagttga tcacaacgat agcgatgatc
     8041 agcagtcctt caaataaatc cccatgttct gtagcaaatg cggtataaaa ggaaatcacc
     8101 gctgctacaa gaaggatgat cgttgtaaaa tcggacaagc ttcgaaagaa ttttttgatc
     8161 atcgattctt tcggcgcctc atcgaattta ttcaatccct gcttttttcg ccgttcatcc
     8221 acttcttgtg aagacaaccc agtatctgga tctgcttctg ttaccttctt tacttcttct
     8281 attgtctgct tgtattcttc catcctattc ctcctttaaa atcttcgtac aaaaaaaggt
     8341 acttatttta ctataacatc ctttttttat ttacttcaaa taaagggctt atcgattatt
     8401 tgttaagaaa gcgtaaaatt taaagtgctt atatttgcaa acgctaccaa aggatgctat
     8461 tatatagatg taaggaagga ggataccatc aaatagacag aagaatttct cgatagaaca
     8521 gtgtaagcaa acaaagttgt tagaagtaca ggtttcaccc agacatgcgt gtagagtaca
     8581 aacctataaa tagtgaatgc gtatggatgt ttggatcacg aagtatccga aacaagaagt
     8641 aatgcgatac gtaacaattg aataacgtaa acgtctgaaa attgaatagg aacaagagat
     8701 gtttcaaatg ttgaagatgt aacgaaaaca aaatttttgt ttaacatgaa gaaattcaac
     8761 accgtgcttt gcatgtatga tggaaagtta caatcatttc tgtttatttg aatccttccg
     8821 aggtacaaga aagccgagct tatcgagagc tcggcttttt ctttgtcata aaatctttgt
     8881 aaagcttttt tgttattcaa aactagcggc ttttcataac cttatttcac gaacatcgca
     8941 tctccaaaac taaagaaacg atagcgctct tcaatcgcat gctggtaagc agataaagtc
     9001 aattctcttc ctgcaaaggc actaactaac atgactaaag tcgattttgg caaatggaaa
     9061 ttagttgaga aagcttctac cactttgaat tcatagccag gcgtaatgaa aatatcagtc
     9121 catccgctgt ctgctttgat ttctccatta aatttcgttc caatcgtttc taatgttcga
     9181 attgaagttg ttccgacagc cacgattttc ccgccatttt tacgtacttg gttcaatcgc
     9241 tcagccgctt cttccgtcaa acggtagaat tcactatgca tatggtgttc ttcaatttta
     9301 tctacgctga caggtcggaa tgtacctaac cctacatgta gtgtcagata gactaattca
     9361 acaccctttg cttcgatctc atcaagtaat tctttcgtaa aatgcaatcc agctgttggc
     9421 gctgcagcag aaccattttc tttcgcatag acagtttgat agcgatctgg gtcttccaga
     9481 cgttctttga tatatggagg caatggcatt tctcccaatg attcaagaat ctctagaaaa
     9541 attccttcat actcaaagtc aatgatccgt ccgccgtgtt ccaattcttc tttcactact
     9601 gcttgcaatc tgccatcacc aaaagagatt cttgtcccaa ctttggcacg tttcgcaggt
     9661 ttgatcaatg tctcccacgt atctccttgt gtattcgtta gaagaaggac ttctaaatgc
     9721 gcaccagtat ctggtttttc tccatataaa cgagcaggca gaactcgtgt attattcata
     9781 actagcgcat caccaggctg taactcttca atgatttcat ggaaatgttt atcttccatc
     9841 tctccagttt tccgatccaa aacaagtaaa cgagaatgat cgcggtcttt taatggtgtt
     9901 tgtgcgatta attcttccgg caagtcaaaa tcaaaatctt ctgttgttaa catatcgtca
     9961 ctcactttct atcatgtgct tcatcattct atcatgtttt tcgttctgtt ggcaaaatca
    10021 gcactttttc acttctattt tttgttttcc taaataaaaa aactacccta tttgtatttt
    10081 ttcattgttt taggcatact agtaatagat agttcttcat tgaaaataga aaaagaggtg
    10141 gcaccatgat tgaatttcaa aatgtgtcaa aaatttataa aggtggaaaa gtcgctgtag
    10201 aggacgtcaa tctttcattt gaaaagggtg agttcatttg ttttatcggt acgagcggaa
    10261 gcggaaaaac gacgacgatg cggatgatca accgaatgac tgatccaaca caagggaaaa
    10321 ttttgattga tggaaaatcc atccaagaaa ttgatccagt ggaattgcga cgtcagatcg
    10381 gctatgttat ccaaagtatt ggattgatgc ctcacatgac gatccgtgaa aatatcactc
    10441 ttgtccaaaa attgttgaaa gtcagtcaag aagaacggaa taaaacagct gaaaaaatga
    10501 ttgatcttgt ggaattgccc cgtgagatgt tagatcgcta cccacatgaa ttatctggtg
    10561 gtcagcagca gcgtattgga gtcgttcgtg cccttgcagc gaatcaagat atcatcttga
    10621 tggacgagcc attcggtgcg cttgatccaa tcactcgtga ttccttgcaa gaccttgtca
    10681 aagatttaca agagcgtttg ggaaaaacga tcgtatttgt aacccatgac atggatgaag
    10741 cgattaaact agcaagccgt atcgccatca tgagtgaagg ccgtgtgatc caatttgata
    10801 caccagaaaa tattttacgt catcctgcaa acgatttcgt agaagagttg attggagaag
    10861 atcgcctact acaagccaag ccaaatgcga caagagtcgg cgaagttatg ctaaatacag
    10921 caatcacgat tacaccggaa aaatcattac aagaagcaat caaactgatg agggaaaaac
    10981 gtgtagatac gttgttagtt accgataatt cgaatgtatt aaaaggattt atcgatgtag
    11041 aaacgttgaa taaaaaacga ggaaaagtat ccagtgtcgg cgacattttg aataaacatg
    11101 ttttttacgt aaaagaatcc gcctatcttc gtgatacctt gcaacgcatt ttaaaacgcg
    11161 ggctgaaata cgtgccggtc gttgatgaac agaacaaagt cgtaggtatc ctgactcgtg
    11221 catcattagt ggatatcgtc tacgatgtga tttggggaga agatcccgca actactgatg
    11281 ttgcagagtc agctactcct gaagaatcta aggaggtctg acctatgcag cagttttttc
    11341 atcagcacgg ttcagaaatt ctctcaaaag gttttgaaca tctttatatt tcaggacttg
    11401 ctttgatcat tggtatcatc attgctgtac cgcttggtgt cttactgaca cgttttccaa
    11461 aagctgccac gattgtgatt ggcttaacca gtgccttgca gacaatccct tctcttgctt
    11521 tattggcatt gatgatcccg ctatttggcg taggtaaatt acctgcgatt atcgcactct
    11581 ttatttattc attattgccg attttacgta atacgtacat tgggatgaaa aatgtcgatt
    11641 ggaattatcg ggatgtggca aaaggcatgg ggatgactga gttccaatcc attttttccg
    11701 ttgaattgcc cattgctatg ccaacgatca tggctggtat tcgtttagct gccgtttacg
    11761 tgattgcatg ggctacactt gcctcttata tcggcgctgg tggtttaggc gatttgattt
    11821 ttagtggact gaataattac caaccagatc tcattttggc aggtacgatc cctgtaacaa
    11881 ttttagcact attggctgat tggcttctag gtctcttgga acaccggctg acaccgatcg
    11941 cacttagaga ggagaatgaa gaatgaaacg tatactaaaa atgaccatgg ttcttttctc
    12001 tcttcttata cttgcgagtt gttccttccc tggtcttgcc agcaatacag atgaagacac
    12061 catttcgatc acaggtggaa tcacttcaga agcacagatc ttagcaagtc tagttgccgg
    12121 aatggttgaa cattatacag ataaaaatac cgcaatcatc aacaatctgg ctactacaac
    12181 tatcaaccat caagcgatga tgaacggaga tgcttcaatt tcagcggctc gctacacagg
    12241 aacagattta acgactacat tgaaccttcc tcctgaaaaa gatccgaaaa aagcgtttgc
    12301 taccgtgaaa gatgaatttg agaaaagata cggtcaaacg tggttcccgt cctatggttt
    12361 tgaaaatacg tatgtctttc ttgttcgaaa agacaccgca caaaaatacc atctatctaa
    12421 agtcagcgat ctgaaaaatg tagcggatga attagtagct ggtgtagata cttcttggat
    12481 caatcgtaaa ggagacggtt atgacggctt ccaagaaact tatggcttct ccttcaattc
    12541 gatattacct atgcagattg gacttgttta tgacgcagtc gaagcaggaa aaatggatat
    12601 tgttcttggc tactctacgg atggacggat cgccagttat gatctagtca tgttggaaga
    12661 tgatcgtcaa ttcttcccac catatgatgc tgctccagtt gtagacaaca agatattagc
    12721 tgatacgcct catttaaaag aagccttaaa taagttaggt cataccatca gtacggaaaa
    12781 aatgcaggaa ttgaactacg aagcagataa taatctagtg gaaccatcag tagtagcaca
    12841 acgtttctta caagaaaacc actattttga agggaagtga agcaattgga taaaatgaat
    12901 gtctttcaac aatttttcta ttatttccag gaaaatggct cctatatctt tgcacaattt
    12961 atccgtcact tcctgatttc tatctatggt gtcctctttg cagcagttgt cgggattccg
    13021 gttgggatca tgatttctag gagacgtaaa ttagcaaact gggtgattcg tttggcgaat
    13081 atcatccaga cgatcccttc tctagccatg atctccattt taatcattgg attaggcctg
    13141 ggagtcaatg tcgtgattgt tactgtattt ttgtattccc tcttaccgat catcaagaat
    13201 acgtataccg ggatgatcca agtagacaaa aacatccttg atgtcggcaa aggcatgggg
    13261 atgactgcta gacaacgact attcatggta gagttaccac tctctgtttc tgttatcatg
    13321 gcaggcataa gaaacgcgtt agttgttgcc atcgggataa ccgcgatcgg tgcattcgtc
    13381 ggtgctggtg gtcttggaga tatcattatc cgaggaacca atgcaacaga gggcacatcg
    13441 attattttag caggtgcatt gccaactgca ttaatggcga tcatcacgga ctggctttta
    13501 ggtattttgg aaagacggct agatccagcc agccgtacat cacgctgatg ttattgtaaa
    13561 aaacaaaagc ttctgcgacc atttgttggt cgcaaaggct tttttagttc tgtcattttt
    13621 aaggcaataa tccactctga ttcttccctc cttatgggca aagagttgct tttcttagct
    13681 atttatccat tccgtatact ccaacttcat actgccaacg ggttcatatc tgcatccacc
    13741 gactaagttt ttttcttatc cgctaaggca ttttgccaat ccattttccc atcactcgtc
    13801 atggaattca taccacatga tctctaaata ctcgtctgct tgttctttga attgggcatc
    13861 aattcttaca tcctttggcg tggctttcat ttaagccttt tccatcagtc ctcgattgtt
    13921 cgatgccttc agctgcatca tcaaaactgg tgactgccgt atcggtaact tcgatcatct
    13981 tttatacaat cgggaacttg ccatcctcat ccttggctaa aaacatatct agccattcca
    14041 gcttctcgcc atgggaggtt tgcggttcct aaaaccggta cacgattctt atggactgca
    14101 tccgtcgcaa ctagacttgg cgatacgatg atccttcacc agaagagcac ccccgtaaac
    14161 caattgatcg atatattgcc aataagaaaa gacattggcg taaaagatat cgatccctcg
    14221 tgatgcattg ccgttgatac tgctattcat ggccgaaagc gccacgactt taacttcttc
    14281 cgtttgagtg acattcatgt tcggcaatgt cgctttggat acccgctctg ctaaaggaac
    14341 gacactggta ttgtatttcg tatctgtatc ttttccaaaa gaccatgcca acgaatcctc
    14401 tgggaaccaa taagacgact ccggttgatt gtccattgct tttttcaaca tacttttggc
    14461 tgtttctcga taaacgacat ttccaattgt cttcgcctca ctttggcgat aatcgatggt
    14521 cgttgccact gccaacacta acaacgatgc tccaatttta ctgattttcc ttgtcacact
    14581 tcttcctcct tgttttacat aaacccgtca acattccatt cctaaactca aacaatgacc
    14641 cttcaaaggt ggagatatag gaacaaatta aagaaatcat gcaataaatc caagaaggtt
    14701 ggttttagaa caaaaaaaga gtctcctttt tggggagact ctttgttaac tatctaaaaa
    14761 ggttggctct tctcacttca ctcataatgt gtccaggcag aataaatttc tacaacttta
    14821 ttttcctcat caactttgta aaccactcga tgctgtctat tcagcctgcg tgagtatctg
    14881 ccttcatgtg taggtctcag cttttcaaaa gactgcgtgg gcatatatgg atcttccttc
    14941 aatgtctgaa tcacttcttc aaattgtttc tttaaattcg tttgcttgat ttttcttaaa
    15001 tccactttcg cagagttttt gattgcgact gtatagttac tcatcaaaga gcttcccaat
    15061 caatatcatc gatattcgta aagctactgt cgtctttttc gcggtctcgt actttatcta
    15121 aagtacctgt ttgctcaaga aaaagggttt cttgaatcgc tctccagtct tccagcccaa
    15181 tcaatacagc attgtttcca ctacgatcac taataatctc gatttcagta tgattttcat
    15241 ttacctcttt caataactga taaaaatttt tacgagcagt gctaggattc atcgttgtat
    15301 tagccattgt ctctcctcct ttttctgata taattatagc gtacttgatt aagtacgtca
    15361 aaaaaataca ataaagcact taaattcagc aaacttttcc tcttttttac atagagaaaa
    15421 agaccccttt ttagggagga tctttgtcca cgctcacttc ttactccttt acgactagcg
    15481 gtagccaaac gtaaagtaat tggtaacaac gtatcatctt tagcaaaggt cgaatccaaa
    15541 gcctgtgagt ctatgcaaca acaccaatac acgaaggttc ctcgttgcag tgtgacttga
    15601 ttgatatctt gaataacctg aggatacgca cgaaagattt gtaacggtta ttcaaaactg
    15661 attttggccg tcaagtcttc tactgcctca aaaatgattg cctctttcgt ctcctgtcat
    15721 tcatgttcac tatcgatttg atacttgctt agaccgttgg gtttgtgaat caccaattaa
    15781 aaatggcact gagttatggt aacaaaaaat ggtcacttga cgaggctgag attcctactt
    15841 atgaagacac atggcactta agagtcgagg taaaggaaga agctgaaaat ataggaggct
    15901 gtacattatt tggcaaagga ttcggaaatt atgatcaaga catcaaaatc aaaatgtttt
    15961 acagctaaat aggaagaata ataacatttc atacgctgtt cccatcttta atggcttata
    16021 gagggcacct ttagctgaga ataagacaaa acagaccctc tagcttcaat taagagctag
    16081 agggtctgtt tttgatttta aaacttggtt tatttcttca aatggtagct ataggtgctg
    16141 acaacgatat tttcacgcca agacaatcgc aatcttaacc gcaaacttgt ttggttatgg
    16201 agaatattct gccagcgtct gtttggtaca aattgaggaa tcaacacagt agttgtatag
    16261 ttttgtttcg ctgcattttt acttacgata tctacataac ggataattgg attttcaatc
    16321 gagcgataag aagagtggac gattgaaaaa cggacatctg ggaaatgctt tttaaattct
    16381 gcttcgattt ctttttcttt ttcgacatct tcgtctagcg aaacatgcat cgcaacgaca
    16441 taatcaccga tcgaacgtgc gtaattcaac gcaccgatat ttacccgtgt cacattcccg
    16501 actaatacaa gaacggtatt cccgtcataa tcatgtagtt ttgcatcatt ttctaaacga
    16561 agctgttctg ctactttttt ataatgatca tggatcttat aaaaaatgaa cataacgatt
    16621 ggcataatga tgaagaaagg ccaaatgtcc cctaaccgat agacaaacaa aatcgcaatg
    16681 attgcatatg agatgaacgc acccgtaata ttggcaatcg atttgcttaa ccatcttttt
    16741 ccttcttttt tccatttgac gaccatccct gtttgagata aagcaaatgg aatgaacacg
    16801 ccgatagagt ataacggaat caagcgttct gttgagccat ggaaaataaa cagcaatacg
    16861 atcgaaccta gcgctagtgt gataatccca ttggaatagc ctagtcgatc cccacgatct
    16921 tgatacatgt gaggcatgaa tttatctttt gccagattgt atgcaagaac tggaaaagca
    16981 gaaaaaccgg tgttagcagc aactgctaaa atcagcgctg tagcaaattg aaggacgtaa
    17041 tacaaaatac catgtccaaa gacagcttta ccaatttgag acaaaacagt gacttctttt
    17101 tcaggaacga tcccatacca atagttgata aatgtgatcc ccacgaagaa gaaacctaag
    17161 atcaatgcca tcatcgtcaa tgtagcagcg gcattttttg ctcttggctt cttaaagaat
    17221 ggtacagcat tactaatcgc ctccacccca gttaaagagg aagaaccaga agaaaatgct
    17281 cgtaaaatca aagcgataga aacacccggc acagccgctc ctggaagtgc agtagcttgc
    17341 aatggcacag cacctgtcac gatattatat aaaccaacaa cgatcagtaa cgagatcaca
    17401 aggataaatg tgtacaccgg aaataatagg aacgatgcag attccctcag cccacgaaga
    17461 ttcagcatca tcagtagcaa aacgattgtc acagaaatag cgacttgatg accgtagagt
    17521 gctggcaccg ctgatgtgat cgcttcagca cctgctgaga cagatactgc tactgtcaac
    17581 atgtagtcga tcaataaaga gccaccggaa atcaagccag cattctttcc aagattctca
    17641 ctgctgacga catatgctcc cccgccatga ggataagcat ggatgatttg acgatatgat
    17701 agcgttaatg aaatcaataa aataataaca aaagcggcaa tgggtagcga ataccagatg
    17761 gctgcagcag acaaagcgac taaaacgaca acgatttgtt ccgtaccata tgcaatagat
    17821 gataacgcat cagacgacaa taatgccaaa gcagcaaatc gggttaattt gtgctcatca
    17881 ttttcagcag attttaaagg cttacctact aacaaccttt ttaagtaatc caatttctaa
    17941 actcctttac acacaatttt acttcaagtt ttatagtcga aaatttatag taaacaagat
    18001 gttatagtac gctcactgac cttaaaagtc aataaacttt aagaaaataa ttggaaaaaa
    18061 acagaaaaat atcaagcgct ttttcaaacg ctttaataca gcaaaaatct aacatttttt
    18121 tatgggcttt ttctttgaat tctataataa aaggatagaa cttgacttag aaaatcaagt
    18181 tctatccttt ttgatatctt aacttttgga agagagatgt aaggctgctt tctacccatc
    18241 attcttacta ctcgaagcat agcgcagttg tcacaacctc ttgataaacg gtgtttaaaa
    18301 gcttgcatct gcggtaataa gctcaaccaa attaaaaaca taagaagctg tttttatttg
    18361 gtcgttctta ttacttgatg cagagcagct tttttacaac ctcttggtac acggtgttca
    18421 atcagctgac cctcggtatt agctcaaaaa aacggcaaaa tatgaggaac tatttttcca
    18481 tttttttctc taatactcag gtcaaaacac tgatttcaca acctcttttt ttaatgaaaa
    18541 atatggctct catgcgccgc ttctttgaat ttcgtcattt tttcttcgat gaacggatag
    18601 attgccgttc ctacgattcc aaagacaaca aacaaaccga tcatgatcca gattgctttc
    18661 gtagcatttg gccaataaat tcctcctgca gattcccgta acaagtttac cgcatgagta
    18721 aatggcaaga acggattgat catttggaag aatttccctg agacttggat cggatagttc
    18781 ccgcctccgc cagagatcga cagtactaag atgataatag cgatcccttt accgacatta
    18841 tcgaataatg cagccaagac atagacgatc atcatgaacg ctaaggcgat caagacagca
    18901 aatgacacgc tgtagaccgg attttggaca tctactccta gtaagaaaat attccctaat
    18961 gtaacgatca agctttgcgc aatcgccatt gtcaaaaatg tcagcatacg agcaacgaat
    19021 tgttctcgtt tcgtaaaatt gtttcggtct ttctttccta aatagtattc tgtcgtagca
    19081 acacttgaaa gaagaacagc gccgacccac agacatagtg cagtataaaa cggggtgcta
    19141 gctgaaccgt tatttgcgat tggataaagc gcattggttt gtagctcaac aggttgtgta
    19201 aagaagtcac tttcttttgt tgcgtctagt ttcaataatt tgatgacttc gcctagatcg
    19261 acttcttgtt cgccttttcg gatcgcgtct gctgcttttt ggataccagc tttgatattt
    19321 ggccagtcat tgttgatcaa gtccgcagca gcgttcacag ctgtttcgac ttctggcatt
    19381 ttttcattta ctgttgtcaa tgtaccggtg atttcatttt ttagtgctgg ccaatcattt
    19441 tggataaaat cagcggccaa tcctaatttt tgctgaatga tcggtaattc attgttgtat
    19501 aggtctgccc cttcattgat gccattgacg atggtatcca tatttccatt cagcattgta
    19561 ttggcatcat ggatttcttg tccaattgca ggcatttctt tttgatattt ttctaaaatt
    19621 gccactgcat tcgttacagt tgctttcgtt gagctgagaa gcgaatcaaa gtcgatctgg
    19681 tccgctttgc tcagtgcgcc ttgtgcagtc ccaatcgtat cgatgacttg gtctagtaga
    19741 gaagtgacag tggaactgat ttgacctgta ttgataccag caatgatgcc attgatatta
    19801 ttaacaacgg catcaatttg atctagcaat tcatcaatag ccttcgtgtc ttcattttga
    19861 acagctgtgt tcaaagcaga taggcggttt tgcagattgc ttagcaaggg ttttaattga
    19921 tttagctgat caataattgg ctgtaatttc gtatttccag cacttgtttg caatttagtc
    19981 aggaactcga ccagtttatc gattgcattt tgttgttgag atattccgtc aataaagccg
    20041 ttcaatacat tgctgatgtt tttcttttca tcatcagtca gcttaccatc ttcaatagct
    20101 gttcttacag tatctattaa cgaacctgtc gttgttgcca cttgtccaat tgacttcaat
    20161 gtaacatcta cactgtttgt gatgcttggt atcgcatctt tcagctgaga ggcacctgat
    20221 tttgtttggt ttgctagatc acttgcctga ttttctaaat ttttcacatc tggcaagata
    20281 tcttgtactt gttggatgat cgtcaagcct tgttttgctt catcgattcc ttggttcatt
    20341 gtctcttgga tcgaagcaaa atcgccgtcg atctctgcta gttgcttacc ggcattttgg
    20401 atctctggga ttttttcttg caaatcaagg atgatttttg cttgatcttt caactcaggc
    20461 attttgtcat tcaatgcaac gactttttca cccatctcat ctactttagg gatgtaatcc
    20521 acgaattcat ttgctttatt cagtttttcc ttgatttcag gtagttgact ttgtaattcg
    20581 aggacttgtt ttgtgtagcc gtcgatcgtg tccaaatttt catctgttga taaaatcata
    20641 tctttaactt tattgatact tactaggttc gtatcgatgt cgtaacctat ctcattgaat
    20701 actttcaata aagtcgaact ggctgttttg ataaattcat ttgtgatttg cgattggatc
    20761 gaacttgctc ctttatcggt gattttcggt gcaatcgcat tgattttttc atttaccgta
    20821 tattcgattt ttggtttctt gatatcacca ctagtaaaac tcagcagatc ttctgagaaa
    20881 tcctttggca agtaaatacc tgcgtaatac tttccggaac ggactccgtc ttctaattgt
    20941 tcttttgaat caacgaattg ccatcctaat tgtttatttt tatgaagcga ttcgatgact
    21001 tgctccccaa tggccacttc tttaccttga aactctgctg gcttgtctgc actgtaaaca
    21061 gcaattggca gctctccagt atttccatat ggatcccata atgctttgat gttaaaccac
    21121 gcatatagcg aagggatgat catgatcgcg atgatcagaa gtgttgcaat cgggtttttg
    21181 aaaatccgtt tccagtcaag caaatataat cgaagcgtat ttttgattga ctgcatagtt
    21241 ctcccccttc ttcttttttc agctgaatta ctttaccatg tatttcatac ttttttcaat
    21301 cggctttttt caaaaaagtc gaatttttgg acatatcacg gcaattgtct cattgtaatc
    21361 tcttacatat tgagaaataa ttaaggatta cagcctttac tttatcatga aataaaaggg
    21421 aaagataatt ttatgccaaa gtttttatct attatacgta tacgcaaaaa agctaaaaca
    21481 ttttttgtct ttgcccctac aaaaatgttt cagctttttt cgttttttat tcctgtattt
    21541 cttatttttc gaatgacagg atgattttcc cagcaggagg atgtccttca actagctgat
    21601 gtgcttggat gacatgctta agtgaagcag acagattcat tgaaataaaa acatgaaagg
    21661 ctcctttttg gtaggctttg attatgccag caaaggcttc tgcatctaga tattcctttc
    21721 ttggaacaaa cgattcataa aagccttcct ttttttgccg caaatctaga tctgggaggt
    21781 catttaatgc aacatacctg ccgcctggtt tcatgatctg gatgccggtt tctcctttga
    21841 tacttccttt cgtcgcatcg attacaaggt ctgcctgatc agcaaattgc agacctggat
    21901 ttgttttatc ataagcagca aatgctgaag ctcctaattt ttttaccttt tcctcatttt
    21961 tactggatgc actggttaag attcggattc ccttttcatg gagaagctgg atcagacttg
    22021 acccgaccgc acctgatgct cctagtatca ttacagtatc tgtcggctgg atttccgtca
    22081 aatggttgat tagattataa gccgtaattc ctggcgtgac cattccggct gcttcttccc
    22141 aactcatttt atctggaatt tttgctactt ttgctgatgg caacacgact tcttctccgt
    22201 aagtcccgcc gactgcatgg acagctactc gatcacctac atgaacagtt gtgacatctg
    22261 aaccaatctc tgtcacaata ccagcgccat cattacctgg tacataaggg aatttcaatg
    22321 ttcgtatctc tttcatttct cctaaacgca aggcaacatc ataaggattc acactgaatg
    22381 cttttatttc tacacgaaca tgtccagaac cgacttctct gggatgagca tcgatttctt
    22441 caaaaacatc ttgtgcttct ccgtaaccgt taattgcaaa tcttcgcatg gtcaccatct
    22501 ccctttttct ttaagtttac gtttatgtct ttattttgac aaaaaaaatg tcttttcgtt
    22561 ttggcgcatg attcaaaaca aaatagttgt cttttttcgc gtaacgtgtt aaattattta
    22621 tctaaaagcg taaagattac gatttacgct aataaaaaat aattggagga atttgttgat
    22681 ggctaaaaaa tcaaagattg ccaaagcaaa aaaacagcaa gaaacgattg aacgctatgc
    22741 tgctttacgc caggaattaa aagcgcaaaa agattacgaa ggcttgcgta aacttccttt
    22801 agatgctcgt ccagaacgat tgaaaaatcg tgatttaatc gatggacgcc ctcgcggata
    22861 catgcgtaaa ttcgggatgt cccgtataaa attccgtgaa ttagcacata aaggtttgat
    22921 tccaggagta aaaaaagcca gctggtaatc caagtctggc tgtaatgtaa aggaggaggg
    22981 cgcatggacc actccttgga tcatcaaaaa agatacgttc gcttcttcta gcagaaatgc
    23041 tggtactaga agcagacgta tcttttttta cgcacagctg gtcctttttt atatgtaaag
    23101 gctgcatggt tacttcgcta tatttattta gtaacaggag tcagtgcttc gatacccaca
    23161 ctaattttca atgctcggtc aacttctgcc ataatgggtc gatccaaatg gcagaccttt
    23221 tctttcaatc ttgatttatc gatcgttctg atctgctcca acaggataac ggagtctctt
    23281 tctattcctg ttccagtagc tttgatccca atgtgagtcg gaagcttagg tttagccatt
    23341 tttgccgtta tggccgcaac aatgatcgtc gggctaaaat ggttacctag attattttga
    23401 ataaccaaaa ctgggcgtgt tccgccttgc tccgatccca cgactggaga aagatcagca
    23461 aaataaatat ctcctctttt taccatagga tcctccttat tcttgatatt ctcttggtat
    23521 ccgctgtcct aatccgcaag ccacttcata gtggatcgta cctaattgat ctgctatatc
    23581 ctgcatagtg atttctttgt ctgcattttt gccgataagc gtcacttttg ttccgacagg
    23641 aaattcttga ggcaatcgga tcatcagttg atccatacat acacgcccaa tcgtttcaca
    23701 gtagttccct tctaccaata gagaaaaacc ctgcatcttt cgtggccagc catctgcata
    23761 accgatcggt atcgttccga tccactctgc ttcaggagtg atatatgttt ctccatagcc
    23821 gattccttca cctgctggga gttttttgac ttgaatcaat tcagaaacca gctcaagtgc
    23881 tggctgcaat ggataaactt ccggtagtgc gtgcccagag ggattaagtc cgtacattgc
    23941 tactccataa cgaatcatat tgccgattgt ttcatcatgc cataaagccg ttgcactatt
    24001 gctgacatgt acatatcgag gaagttcggg aagttttttc agcacttcta taaagcgttc
    24061 tttttgcaga ttccaatatg tatcatctgc ctgatctgct gtagaaaaat gggtaaataa
    24121 accttcccat tctaatacac gactttcttt gatgaatgca gctgcctctt ttacttcttc
    24181 aggtgtacaa aatccgatac gacccatccc agtgtctgct tttagatgaa tcgaaagagg
    24241 cgtctctagc ttacttttct ctaaaacagc agctgctgct tgcaaccatt cccgtgtacc
    24301 tgcagttact gataaatcat gagcaacagc tacagtcagt gcgtcgtaag gaaccatatt
    24361 caagataagg atgggctgag taaatccagc ttctctcaac tcgactcctt catctaaatt
    24421 tgaaacacaa aagcccgaag ctccacctgc aactgctgcc tcagctgttt caatagctcc
    24481 atgaccgtat ccgttcgctt ttactactgc aaacaattct tttccttgcg gaagtcttgc
    24541 aacttcattt gctacatttt cagttatagc ttttttatgt atcactgctt tcgttgggcg
    24601 gtgccaagcg acaaccatcg tttttccttc tttctagtct tccaaaataa tttgtgcaaa
    24661 agctgtttca tttgtatgag taatactgac ccatacattg ccttcatgag gtgaacgcgt
    24721 cacaacaggc tgaccatttt cattttttaa aatctcgaca tcttgaaagg taacttttcc
    24781 gatcccagtt ccccaagctt tagagaaagc ctctttgcaa gcgtaacgcc cgcctaaaaa
    24841 ttctacttgg cgatgaaaag gcaaggactg gaatagtttc atttcatcag aggtcaagat
    24901 tcgtgcaatg aattttggtt tttcttcgat cagccgagtg atcctaggaa gttcgactgc
    24961 atcgatccca attcctttta tcatatgctt ttctcttttc aataaattta gaacactctc
    25021 attctaccaa attataacca ttttgccaca aataagtcca caaataacaa aaatgaaagt
    25081 ttctcttaaa aaagagaaac tttcatttta tgtttaatcg ttatttgaac ggattacaaa
    25141 tccgcgtttt ttatcattgt gacgtttacc gccatctttt tggctgttat tatttttgct
    25201 ataaccgcct tttgatttgt ttccacgata attaccgccg tcacgacgat tacggttgtt
    25261 tccgccacca cgtttgccat ttttattgta tccttttttc tgcattggca atgggcgttc
    25321 tggtgtgatc ttcactggca ctgcatcagc tggatctttt gctgtcgttt ttagcaaaag
    25381 tgcaactaaa tcttgtgcag aatattcttc taataattta tctgctgttt gcaggtattt
    25441 atctagacca ttttctgcaa gttttgtttc gatttgttca actgcagcac ctaattgacc
    25501 tttgaatgct tctttttcgg ttggtggacg taaagtcgtc atccgttttt tcgtcaagtt
    25561 ttcaatcaca tgcaagtagt ccatttcatt tggtgtaacg aaagtcacag acataccgcc
    25621 ttttccggca cggcctgtac gtccgatacg gtgaacgtag ctttctggat cttgagggat
    25681 atcatagttg tacacatgag tgacacctga aatatctaat ccacgtgcag caacgtctgt
    25741 cgctacaagg atatctaaat gaccgctctt aaatgaacgc aatacgctca ttcgtttttg
    25801 ttgagacaaa tcgccatgga ttccttctgc acggtaaccg cgtgcttcta atccgcgtgc
    25861 caattcgtct acacggcgtt ttgtacgtcc gaagacgatt gttaattcag gtgtttgaac
    25921 atcaaacaag cgagtcatga tatcgaattt ttcgtattct tttgcgcgga catagtattg
    25981 atcgatcaag tcagctgtca tttctttcgc tttgatcttc acatgatgtg gatttttcat
    26041 gaatttaacg ccaatattct tgatagctgg cggcatcgtt gctgagaaaa gtaatgtttg
    26101 tctttgatca ggaacttgtg aaatgatttt ttcgatatct tccaagaagc ccatattcaa
    26161 catttcatct gcttcatcca aaactaatgt ttgaacggtt ccaagtttca atgtgtggcg
    26221 gttaatgtgg tcaagcatac gtcctggtgt acccacaacg atatgtggac gatctttcaa
    26281 gccacggatc tgacggccaa tatctgctcc gccgtaaacg gcttgtacac gtactttttt
    26341 gtcgcgccct aaacgatata attcttcttg tgtttggata gctaattcac gtgttggtgc
    26401 gataactaaa ccttgtaatt cgtgacgatc tggatcgatt ttttctaaca ttggtaatcc
    26461 aaatgcagct gttttccctg tacctgtctg tgcttgtcca ataacgtctt ttccagctaa
    26521 tgctagtgga atcgtttctg cttggatagg cgttgcttct tcaaaaccag cgcgttcgac
    26581 tgatttcaac aattctggtg ataattctag ttctttaaat ttcaaatgaa tcctcctata
    26641 tggttgttaa ctgaggatgt agcttttttg ctaccccgtc gatttgttcg gtcaaagtgt
    26701 attgtttctt tttgacagtg gccacgcacg tttttatcca ttcttagccc ctgtggcacc
    26761 accgaaaaat cactttgcga agtttaggca ttagaaaagc caaacgggtc gcgttcagct
    26821 ttatcattat tatgacatct ggcttcaaca agttgtttct atggcaaaac cagtccaatt
    26881 tctcttcatc tttcggcaat aggttattct aacatagttt ttcgttttct gcaagtttac
    26941 agatttttat ttcatttgct gaagttgttc taccacttca aataagccca tgctgttgct
    27001 gccttttagc ataatactat ctgttgctgc aagattttgt ttgatagcat caatcaattt
    27061 attcttttct ttttcaaaat agaacacagg tagttggggg tatttttggt tcaattcttc
    27121 ttttagtgca tgcatttgtt ccccataaag gaaaatcatg gcgaatttct caggatcgat
    27181 atgttcactc atttgcgcat gcatatttaa agactctttc cctaattcca gcatatctgc
    27241 taacacagcg attctgcgtc cttttgttgg cagattttta aaagtatcta ataccagtcc
    27301 catggctgtt ggatttgcat tgtagacatc gctcaaaata gctgcaccat ttcctgccgt
    27361 tagccattcg gttctgtttt gagtgataga aacatgggcg agcccttggc gtatctcagg
    27421 tatggacagt ccaaagaagc gcccgatcgt atacgcaatc aaagcattcg ttacattata
    27481 acttccaggc agcgggatcg taaatgtttc tccttctact acaaaatcgg tttgtgcttt
    27541 tccttttgct gtcacttccg catgaacatc gccatttcca ataccgaatg ttgtgactgt
    27601 ttgtactaat gttgccgtta aaggtgtcag caacggttca tctgcgggca caacgagtaa
    27661 tccgtctgat acaagtccgt cagtgatttc cattttggct ttagcgattc cttctcgcga
    27721 cccaagattt tctatgtgtg cttcaccgat cattgtgatt gctgcagctt ttggttgagc
    27781 cataagtgaa agttccgtga tttcattggc gtgatccatg cccatttcca aaacgatctt
    27841 ttctgtatct tggggcatgt gcaaaatcgt gtaaggaaga ccaatattat tgttgtaatt
    27901 tccttgcgtc ttatatgttt tgtatttttc agacaagaca gacgcggtta gatctttcgt
    27961 ggtggtttta ccattgcttc ctgtaattgc aacgacttct gcgcctactt tttccaagta
    28021 ataggttgcc aattgctgca tggctttcaa aggatctgct acaggaataa ctggaaaatt
    28081 ttttggagct tgttcaacag gcaagctcca aaatgaagca gatgctccgt ttgtgatcgc
    28141 ttgctggata aattcatgtc catctcgcgt accagcaaga ggaacgaata aacttccttc
    28201 ggttatcttc cggctgtcaa attcgacatt ggtaatcttt gtcagtgcag agcattcgct
    28261 gcccacggct tgtgcaattt cttgtattgt tagattcatt gagatctctc ctaaaaaagg
    28321 ttgtgaaaaa agcgtttggc ctaaacggcg ggttcgcatg actctcactt ccaagtaaat
    28381 ttctctattc gtatttagaa gctagaatga acgcggttac gcaatcactc cagcctcttc
    28441 tttatttctc tttattcatt tttttcaaaa aaagattgac gctgatggta tcgattcatt
    28501 cctaactgga tcagttcttc aatcaaatca ccgtatttca agcccatatt ttcccataag
    28561 agtgggtaca tactgaactc cgtaaatcct ggcatagagt ttaattcatt caggaataat
    28621 tcatttttat ttgtcaaaaa gaaatcgcac cggctcaatc cgcttccacc taacatcgtg
    28681 taagctaact tcgcgtactc ttgcgctttt tgataaactt cttctggcac ttcggctgga
    28741 atctgcattt cgattttatt attgatatat tttgcttcat aatcatagaa tgctacgtct
    28801 tttacgactt caccaggcaa agtcgtccga acgtcttcat ttcctaatac agcaacttcg
    28861 atttcgcgcg cttcaattcc ttgttcaacg attgctcgag aatcatactg ataggctgtt
    28921 gctaaagcat tttgcagctc ttctcggttt tctgcttttg taatgccgac actagaaccc
    28981 atattcgccg gtttgacaaa catcggataa agcaaagaac cttcacattg atcaaatact
    29041 tttttaggat tttctttcca ttgattctta agtactggta cataaggaac ttgcggcaca
    29101 ccagcagctt gtaaaatata cttggtcatg attttatcca tggcacatgc actggtcaat
    29161 acgcctgcgc cgacataagg catattcaat gtctctaaga agccttggat cgttccatct
    29221 tccccgtttg gcccatgtaa aactggaaaa acgatggctc cttcttcttt gatttcgccc
    29281 ggattgatca cttttcctgt aaagccttcc tctgtctgtc cacttgggtc ccatgaaaga
    29341 tgcaagacat ctttgctggc aggtttttct gttagtaatg gacctttgac ccattgtcct
    29401 tcttttgtaa taaatacgag ttgaacttgg taataattat aataaatggc atttaaaact
    29461 gaaaatgcgg aaagaatgga cacttcatgc tctgcgctgc gtccgccata tagtaaagta
    29521 atcttcaaaa gattgtcctc ctgtattcta aatcgttcag tgatttactc tcatatttta
    29581 gcacaaaaca aaaataaacg aataacttat ttataaaaaa acgagccagc ttctaaaaga
    29641 acgagcgtca tttatttttt gtcagctaga ttatttgtcc cgttttttat aaaaagttat
    29701 gataaagaaa aggagggatg atgatggcgc aaacaaatcc acgcagccgc ttggcagaaa
    29761 tcattcgagt gttcatcaat tacaatgtag tgccaaactt tgtacagcaa aaaaatcccg
    29821 aacaggtaaa aaaagccttt gaagaactag gccccacctt catcaagata ggacagatgc
    29881 tttctgttcg agaagatttg ctttcttctg ccttcactca aacattcaaa acattacaag
    29941 atagtgtacc tagcgacaca ttttcaacgg tcaaaaagac gatcgaaaca gaactttctc
    30001 tttcattatc agatatattc gatgattttt caaaatcgcc ttttgcctct gcttctatgg
    30061 ggcaggctca tcgtgccaag ctgaagaacg gtgacgcggt agtcgttaag atccaacacc
    30121 ctaacatcgc cgaagagatc cgacttgatc ttcaactatt tgaacgagcg atccctttga
    30181 tcaaatacat tcctgaaact agcgtagttg atctaaaagg ggtactccaa gaagtaaaac
    30241 gttccttgat caatgaaatg gacttcttaa aagaaagtca aaatggcgaa caattctatc
    30301 aaaagaacaa tggctggaaa gagatccgca gccccaagat ttatgacgct ttttgttcga
    30361 aaaaagtgat cgtgatggaa gaaatgtctg gtaaaaactt gaatcattta atgaacgccg
    30421 aaaacaaaac tgaaactttt atcactggaa ttcaaaacaa gcagctgaaa caagaagttg
    30481 caaagctttt agttgagaac tttatgaaac aggtgtttga tgatggtttt ttccatgctg
    30541 atcctcatcc agggaatctg ctattccatg tactaacaaa agaagaacag acacaagcta
    30601 gccgaaaaac tgaaacagtc catgaaaaag agttcggttc ctttgctttt cgagcctcca
    30661 cttctgcaga agaccctgtt gcgccatata ccatcaacta catcgatttt ggtatgatgg
    30721 ggcatctttc tgcaggactt aggcaaaaac tcacacaagc cgttttagcg ctgtatacga
    30781 aagatgctta tcgaatcgaa aaagcggtcc ttcgactttg tcagcaagaa ggctcgtttg
    30841 atgaaagtcg gttccaccaa gaactgacaa gttttcttga acagtattat gattctccta
    30901 ttgatgaaat caacttgcaa gaagtattca cacatgtcgt gacgatttgt catcaaaata
    30961 atctgcagtt cgatcgtgat atcacgcttt tgctgaaagc atttgggaca ttagaagggg
    31021 tgatccgcgt cctcgatcct gaagtttccc tcatggaagt cgcttcgcct tttgctcaac
    31081 attattttct cactcatctg gatgtagaag atacattgaa acaaagcgga ttagacttat
    31141 tggaagggat gaaggctgcg cctaagatcc ctcaacagct ccaccatcta ttagaaatgt
    31201 ggacttcggg acaaggaaaa gtcaatttgg aattgaaaaa gcaagacaaa ttattgagca
    31261 ggatcgaaag tatgatcaat cggcttgttt tcggtatgat tttagctgca ttgatcgtag
    31321 ggtcctccct gcttgtccaa gcagcacctg tagaaaacgc agaggtcgtt tccttattag
    31381 ggatatttac gtatgctatt gccgcattcg tcattatttt tttggcaatc gatgcattga
    31441 tccaaatgta taagaagagg aaaaagtaga aaaaggttgt gacagaaaga atcagcttca
    31501 agaaataaga aggggtttta cataaattgt ttctcaaatt tttgtgaaaa ttcggcttat
    31561 ttttcgaaga ggctacttct gaaacaccga gaataaaaaa tgtgaaaaag ctgttctgca
    31621 cccagtaata agaacaatca aaaagggaac atggaacaca tttatcctgt ttccctgttc
    31681 cctttttgat gtattcgagc ataaataaaa taccttcgtt acctactatc ttctgtactt
    31741 ggtaaacctt agtcaattgc cttttttaac gcttgacgaa aagacatatg atctttctcc
    31801 gtaaagggtt ttggaccctt tgtccttatg ccagcttttc ttaactttcc actatgataa
    31861 cgttgttcta gaagcgtgcc gatattcgct tcgtcaaatt cttttccaga gtgatggaac
    31921 actcgcacac ccttcggcaa tacaagtgaa gctaaaccat aatcttgcgt gatcaaaaag
    31981 tcattcttct taaccatacc gacgatttta taatccgcac tatcagctcc gcggtctacg
    32041 tagacgattt ggacatgatt agcgtattct ttggtcgtat aatggtccac actggtcacg
    32101 ataaccacgt caagaccata ggattctcct aattttatga catcttcttt tactggagaa
    32161 ccatctccat caatgaatag cctcattctt tttcgccttc ttccataaat gataaacagt
    32221 tactaatccg ctcagtaaaa gaccaacatt gatccatttt gccaagataa gcagttgtac
    32281 actttctatc ggcactgatt catggttcag cgtgatcaat aatagatgga ttggctctcc
    32341 catttctttt gctaaaacaa acaaaagcgt catcaataaa aactggtgga tcacactccc
    32401 tttattttga gtagtatact tgacaacgat ccggcgatcc attggaatag ctgtatcagt
    32461 ttgataatat tccttattta gccagctgcc tgttactacg tgccagaaac taagcagaaa
    32521 gacacctatc gcaaaaccat ttggaatcaa gaggaccaat aaagaagaac tcagtccaag
    32581 caattgcata gccaatggag accatgttaa acgtttcaaa atccatggtc cgactatttt
    32641 tgctgcaatc aagcctgctg cataaggcaa atacataaaa atcgaaagtt tttctaatcc
    32701 gtacagtatg ccaacataaa aactgctaaa taaaaaaagg aaattcccta gcattccatt
    32761 tagaaaagta aacagattta gccagcttgg caacttccat tccttcttct ggtgtcctaa
    32821 aacaaacacg aacaagatga acagcagcaa gaaaccataa atagcaagat caaaaagcct
    32881 ttcatcgaat aacaatcggg catttctcaa aagaaacaat aagccaaaga atatcaaaaa
    32941 taaaacaagc tctcgcgtag ctaccagatt tcttttgatg tctttgaaat ccagttcgta
    33001 acgcggataa tgactaaccg tatggtaggc catgacgtaa aaaagtgtat aaatagtaaa
    33061 gcttgctgca atctgagtcg gtgcaggcaa ctcaatcgct tgatacagga gaaatagcca
    33121 gatagctgca aataagtact ttttcccatc catattgata aaaccttgcg tcttttcgtg
    33181 aaaattgacc gtggtattag caggtacaag ccatgctgca ctcagcccta gcaaaacact
    33241 tgaaaaataa aataaaggaa aataaaatac gcctaatatt ccaagcaatg aaccagcacc
    33301 accaatcagc agagcgatca tcagcaacgt gtaactatct agaccaaatc gtagactgtt
    33361 gactaaaaat agtccagtca tccgaaaggc ataaaacagc gtaaatggca aaatcgtcag
    33421 ccaattatgc gagtctgtta gtcccaaaaa taaaagataa ggaataaaaa taaccgtgtt
    33481 acttaagata aagggcgttg tttgtgtaaa attacgccca aatcgtttga gtttttcgaa
    33541 catgacaatg gctccttaaa cagtcttata actaatctgc tcttcgattt tagcattaaa
    33601 ggggaaataa accaatttta cagaatatat tcttgtaaaa aaaaatacag aaagaagcat
    33661 aagcttcttt ctgcattttt acggtacttg attactcaag cagacaagcc cttctccaca
    33721 aaagtcttgc ccgacacccc tgcatccggc aggtgataaa gatagaaatc aattatcctg
    33781 tgcctccaaa atcaattagg agctctgtaa accagagtcc ttctcgaccc gtcgcataaa
    33841 tttactttaa cacagttcct atgtttatgc gagagctttt ttcattttat aatcgaccat
    33901 ttgaaatcct tgaccgatat ctgaaataag ttcttctgta atctcaaatc cttcatgctt
    33961 ataaacctcg attgcttgat gattcccctg attcactcgc aaaaagatct ctctttcctt
    34021 tgtttgcgca gcaagttctt cataccagcg aaaaactgaa gaagtcaatc cttgaccacg
    34081 tactttattt agcaaatata atttacttaa ataaattttt ccatttatct cttcataagc
    34141 agtgtaaccg acagtctttt cttcgctttt taataaaaag taggacacac cttctgtcag
    34201 ttctttttga atctgttttt ttgactgata agttttcagc atgtaatcca cttgtttttg
    34261 accaatgatc ggcacaaaag cttccggcca tacttcttgt atgactgcca tcagctcatc
    34321 cagttcattt tctgttactt ttattttttc catacaccca cgtccttttt tacattataa
    34381 atgaccttgc gcttgatgga ataaaaagag catgatcatg ctatacacac ccaccgacca
    34441 tggtttcaag aaaatcacaa tctgcataaa ttccctaaaa gataatttcg tcaaaccagc
    34501 tactagacag atcaagtcgt ctggcgcaaa gggaagcagc aaggtaacaa ctagtacttt
    34561 tttaatatct ttcgtttttc ttgtcagcaa ttcatcaaat ttctgatact tttttggcga
    34621 taaaataagc tggacaaagg ctacgccata gtaacggaca agcaaaaatc cgattgcttc
    34681 cccaatcact aggccaatac aactatataa aagcccaaat ccattgccaa acatcagcat
    34741 gcccgctact gaggagatcc ctcccggcaa aataggaatg atcacttgga tcacttgcaa
    34801 cagaacaaat atcatcactg catacttgcc aaattgctgg ataaacgctt gcaaagacgt
    34861 gctcgatcga aaaatcccat gatgataagc ataaagaatc aacacaaaga aaaaaaacag
    34921 accaataatg ggcatgatct gaagacattt ttgtaaaact gatccttttt tagacatcta
    34981 tattccccac atcttttttc atttattaaa actgcctcc
//
LOCUS       DACBZK010000023        34636 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.023, whole genome shotgun sequence.
ACCESSION   DACBZK010000023 DACBZK010000000
VERSION     DACBZK010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.023"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            591..1280
                     /locus_tag="IVD66_001176"
     CDS             591..1280
                     /locus_tag="IVD66_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6145412.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="IVD66_001177"
     CDS             1267..2475
                     /locus_tag="IVD66_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP6145413.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="IVD66_001178"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="IVD66_001178"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HAP6145414.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="IVD66_001179"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="IVD66_001179"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HAP6145415.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="IVD66_001180"
     CDS             complement(6578..7273)
                     /locus_tag="IVD66_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HAP6145416.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="IVD66_001181"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="IVD66_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HAP6145417.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="IVD66_001182"
     CDS             complement(8472..8663)
                     /locus_tag="IVD66_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HAP6145418.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="IVD66_001183"
     CDS             complement(8684..9574)
                     /locus_tag="IVD66_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HAP6145419.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="IVD66_001184"
     CDS             complement(9561..10328)
                     /locus_tag="IVD66_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP6145420.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="IVD66_001185"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="IVD66_001185"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HAP6145421.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="IVD66_001186"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="IVD66_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HAP6145422.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="IVD66_001187"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="IVD66_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HAP6145423.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14944..15282
                     /locus_tag="IVD66_001188"
     CDS             14944..15282
                     /locus_tag="IVD66_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145424.1"
                     /translation="MSPFRSAALEEESDPRINDVVLSTGNINQKYIVRDIVFVVECLE
                     ADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQKKRDGKYFLELFAYGT
                     VIQFIQTTIG"
     gene            complement(15450..16208)
                     /locus_tag="IVD66_001189"
     CDS             complement(15450..16208)
                     /locus_tag="IVD66_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAP6145425.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="IVD66_001190"
     CDS             complement(16226..17044)
                     /locus_tag="IVD66_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAP6145426.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="IVD66_001191"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="IVD66_001191"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HAP6145427.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="IVD66_001192"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="IVD66_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HAP6145428.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="IVD66_001193"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="IVD66_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HAP6145429.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="IVD66_001194"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="IVD66_001194"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HAP6145430.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21063..21305
                     /gene="yaaA"
                     /locus_tag="IVD66_001195"
     CDS             21063..21305
                     /gene="yaaA"
                     /locus_tag="IVD66_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HAP6145431.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21292..22416
                     /gene="recF"
                     /locus_tag="IVD66_001196"
     CDS             21292..22416
                     /gene="recF"
                     /locus_tag="IVD66_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HAP6145432.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22413..24359
                     /gene="gyrB"
                     /locus_tag="IVD66_001197"
     CDS             22413..24359
                     /gene="gyrB"
                     /locus_tag="IVD66_001197"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HAP6145433.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24379..26850
                     /gene="gyrA"
                     /locus_tag="IVD66_001198"
     CDS             24379..26850
                     /gene="gyrA"
                     /locus_tag="IVD66_001198"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HAP6145434.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27086..27385
                     /locus_tag="IVD66_001199"
     CDS             27086..27385
                     /locus_tag="IVD66_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HAP6145435.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27435..27947
                     /gene="ssb"
                     /locus_tag="IVD66_001200"
     CDS             27435..27947
                     /gene="ssb"
                     /locus_tag="IVD66_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP6145436.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27973..28209
                     /gene="rpsR"
                     /locus_tag="IVD66_001201"
     CDS             27973..28209
                     /gene="rpsR"
                     /locus_tag="IVD66_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HAP6145437.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28352..30325
                     /locus_tag="IVD66_001202"
     CDS             28352..30325
                     /locus_tag="IVD66_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HAP6145438.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30331..30783
                     /gene="rplI"
                     /locus_tag="IVD66_001203"
     CDS             30331..30783
                     /gene="rplI"
                     /locus_tag="IVD66_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HAP6145439.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31057..32424
                     /gene="dnaB"
                     /locus_tag="IVD66_001204"
     CDS             31057..32424
                     /gene="dnaB"
                     /locus_tag="IVD66_001204"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HAP6145440.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33204..34496
                     /locus_tag="IVD66_001205"
     CDS             33204..34496
                     /locus_tag="IVD66_001205"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HAP6145441.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10554 a         6733 c         6844 g        10505 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tatattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg
    20941 tttaaatcac cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt
    21001 tttattgcga aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg
    21061 cattgaaaca acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag
    21121 aagtcacagt tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt
    21181 tagtcgatgg cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg
    21241 aagttccaga agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg
    21301 aataagctgt atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag
    21361 aacctcgtca tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc
    21421 tacgtattag ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg
    21481 actgacgatc aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta
    21541 gaaatcttat tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag
    21601 ttaagtactt acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta
    21661 gtaaaaggca gcccgcagac caggcggaag tttttagata tggaattagg ccagatcaat
    21721 ccaatctatc tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac
    21781 ttgaagcaat tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa
    21841 caactagcag cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg
    21901 gagttttggg ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc
    21961 gagtatctca ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa
    22021 tttctcgcac ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt
    22081 ggtcctcatc gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga
    22141 tcgcaaggac agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt
    22201 aaagaagaga caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat
    22261 gataatcgtc aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca
    22321 acaacgacac ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt
    22381 caacaaggga aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac
    22441 gcgctaaaga gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta
    22501 aacgacctgg catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg
    22561 aaattgtcga taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga
    22621 ttattgaaaa agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata
    22681 tccaggcaaa aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag
    22741 gaaaattcgg cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg
    22801 ttgttaacgc gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact
    22861 atcaagaata tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc
    22921 gccatggaac aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt
    22981 ttgatttttc aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc
    23041 gtatatcgat tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg
    23101 gcgggattaa aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac
    23161 ctgtatattt ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag
    23221 acggctacca ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggcggaa
    23281 cacatgaatc aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac
    23341 aaaagctgat gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga
    23401 cagctgttat ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat
    23461 tgggcaattc cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat
    23521 tcttgctgga aaacccaagt gtgggccgtc aaattgttga aaaaggatta ctagcttcca
    23581 gagctcgtct agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga
    23641 ttagtaatct gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat
    23701 tgttcatcgt cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt
    23761 ttcaagccat cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca
    23821 agatcttggc aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag
    23881 aagattttga tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg
    23941 tcgacggcgc gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta
    24001 ttgttgaagc tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga
    24061 agaatattac gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg
    24121 cttcacttcc tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg
    24181 atgatcatca actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca
    24241 gtgtggacga tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag
    24301 aaccccgtcg tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat
    24361 catgaaggag gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta
    24421 accagcgaaa tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca
    24481 cttcctgatg tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac
    24541 gaattaggtg taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc
    24601 atgggtaaat accatcctca tggagactat gcgatctatg agtcaatggt acggatggca
    24661 cagccattca gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac
    24721 ggtgacggtg ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa
    24781 atgctgcgtg atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa
    24841 aaagaaccag ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg
    24901 atcgccgtag gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct
    24961 atcgatttgc tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct
    25021 ggaccagatt ttccaacagg tggtttggtt atgggaaaat caggaatccg aagagcgtat
    25081 gaaacaggta agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat
    25141 ggtaaagaac ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc
    25201 gaacggattt ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac
    25261 gaatcttccc gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatct
    25321 gttatcttga ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg
    25381 ttggcgatcg aaaaaggtgt gccgaaagtt ttgagcttga aacaaattct tgaaaactat
    25441 atcgaacatc agcgcgaagt catcacaaga cggacagtct ttgaaaaaga aaaagcagaa
    25501 gcaagggcac acattttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt
    25561 gcgattatcc gcgggtctaa atcagatgac gaagcaaaag cgacgatgat cgaacggttc
    25621 gatttatccg atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt
    25681 ttggaacggg aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta
    25741 actgacattc tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac
    25801 ttgaatcaac gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt
    25861 ctggaagatg aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt
    25921 tacatcaaac gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc
    25981 caaggaatgg gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat
    26041 gatacattgt tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt
    26101 ccagaatacg ggcgcacagc caaaggaata ccaattatca atttactagg tatcgattcg
    26161 agtgaaagca tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc
    26221 ttctttacga cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc
    26281 cgaagtaatg gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta
    26341 ctgacagatg gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc
    26401 aaagaagaag cagtccgcga tatgggacgt acagcttccg gggttagagg aatacgcctg
    26461 cgtgaggaag attatgtcgt tggggcagcc ttaatgaagg aagatcaaga agtattagtg
    26521 atcacagaaa aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc
    26581 ggaggtaaag ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg
    26641 accactgttt ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt
    26701 ttcaacgtat cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag
    26761 atggaagctg atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa
    26821 acagttgaag aacaaggatc agaagaatag ccatcaagac taattgtgta agctagcaag
    26881 aatgaccgat taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct
    26941 taaaatattc gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataatcag
    27001 agcttgtgag tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg
    27061 aaagtccaca gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat
    27121 tcgtccaaac attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt
    27181 gaaagataac ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta
    27241 tgaaatgaac ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc
    27301 agcaaatgct gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca
    27361 catgattgtt aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag
    27421 aggagatgac tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag
    27481 atttgcgtta cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta
    27541 attttacaaa ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca
    27601 aatcagcaga aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac
    27661 gtatccaaac tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag
    27721 tagctgacaa cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg
    27781 gcggattcca aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc
    27841 aaacatctca atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg
    27901 gctcaagttc aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag
    27961 gagggaaata gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac
    28021 attgctgcta accatattga atatatcgat tataaagata tcgaattact aaaaagattt
    28081 atttcagaac gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa
    28141 cgtaaaatta ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc
    28201 gaagactaat aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct
    28261 ttttttctgt aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa
    28321 aatcaaatta gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc
    28381 gaaacctctc ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc
    28441 atttcgtttt gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg
    28501 gttgaaaatg aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac
    28561 tgtagctgaa accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta
    28621 tcagccatca agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca
    28681 aagtggatta acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa
    28741 aaaccaagtc tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt
    28801 tgtttatttt aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca
    28861 gccggtgatt ggtattttat ctattgataa ctatgcagat gccattgata aattggatga
    28921 caaagagatt tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga
    28981 ataccatgtc tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat
    29041 cgatctgaaa aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc
    29101 tgaaaaacag agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct
    29161 cgatgaaatc ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga
    29221 ccaagttgtc gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc
    29281 tgctaagaat gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg
    29341 gatttttgat gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc
    29401 tttaggctct gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat
    29461 cgttatcaac gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa
    29521 gcatcctgaa ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga
    29581 agaggacctc ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct
    29641 atatgagcaa tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc
    29701 aagtaaacct ctgctgactt atatcgaatc ttcagcttct tcagcttcag agctagtttc
    29761 tgagctgatc caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt
    29821 attgcttgca gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac
    29881 ttttgacgtt gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt
    29941 attgagctcg gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta
    30001 tgtgacttct gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat
    30061 agcagcaaaa acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat
    30121 tacaaagcgg acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt
    30181 ccaaatcatc atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact
    30241 ggaaaatacg acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat
    30301 gaatcaaata tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa
    30361 ggaaaaggta aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta
    30421 atcaaaaata acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa
    30481 aagaaagcac aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa
    30541 ttcttggaaa aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt
    30601 ttgtttggtt cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc
    30661 aaattagata aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac
    30721 gtacctgtta agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa
    30781 taacaaatct tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac
    30841 cgaaatttat ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag
    30901 attgatttcg gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa
    30961 aagagaacta tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt
    31021 gtaaaatgaa gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga
    31081 atcccaccgc aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca
    31141 gaaacgatca ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat
    31201 caaattattt ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt
    31261 actgtcaaag accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat
    31321 ctctcagact tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc
    31381 gttgaagaaa aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa
    31441 ggattcgagc aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg
    31501 gaggtttcgg aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc
    31561 acgattgaaa atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact
    31621 ggctatcaag gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt
    31681 gctgcacgtc cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga
    31741 acaaaaacag atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta
    31801 aatcggatgc tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt
    31861 tcggaagaag aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt
    31921 tttatcgatg atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta
    31981 gcgcaagaaa aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt
    32041 aacggtaaag agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg
    32101 gcgaaagagc tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag
    32161 cgacaagaca aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat
    32221 gcggacatcg tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac
    32281 gatgatggaa acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga
    32341 agcggtgcac gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg
    32401 ctttcgccaa gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct
    32461 ctcgtaagaa gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat
    32521 ctccaaaggg attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc
    32581 aatcagctga cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg
    32641 tttgtttctc taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt
    32701 gttctcctgc caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt
    32761 ttgaaattgc tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg
    32821 gtgttcaaaa gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta
    32881 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    32941 cggtgttcca aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag
    33001 caattttcgt acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt
    33061 ttaataacca ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata
    33121 aaaatcattc gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa
    33181 ataatataga acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg
    33241 atgaagggaa aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt
    33301 accaaggtgg cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc
    33361 atttgattcc ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg
    33421 tagtcaatcc taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa
    33481 caagtaattt gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg
    33541 accaattaca agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg
    33601 gacctgccta tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata
    33661 aagaaatttt tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa
    33721 aaatgtttga ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg
    33781 gacaacaaat caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg
    33841 caggcaaacg cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa
    33901 cttatccttt tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg
    33961 tagggccttc aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg
    34021 gtgatggacc atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag
    34081 gacgagaata cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag
    34141 ttatgcgcca ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg
    34201 tattaagtgg attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa
    34261 tctaccacta tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat
    34321 tgccaggctg gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg
    34381 cacgtaacta tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg
    34441 tcggacctga tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat
    34501 aaaaacgacg actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg
    34561 ataataataa cttgaacact gtttattcag aataagggac tgtgacaaaa accgtgtcac
    34621 agtccctttt tccgaa
//
LOCUS       DACBZK010000024        32078 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.024, whole genome shotgun sequence.
ACCESSION   DACBZK010000024 DACBZK010000000
VERSION     DACBZK010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32078
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.024"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            93..578
                     /gene="mraZ"
                     /locus_tag="IVD66_001206"
     CDS             93..578
                     /gene="mraZ"
                     /locus_tag="IVD66_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HAP6145442.1"
                     /translation="MGDCGRLILVSGGMGGLSMLMGEFQHNIDAKGRLIVPSKLREEL
                     GEKFVLTRGLDGCLFGYPMSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQ
                     GRINIPSTLRNYAALTKGCVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFG
                     L"
     gene            599..1558
                     /gene="rsmH"
                     /locus_tag="IVD66_001207"
     CDS             599..1558
                     /gene="rsmH"
                     /locus_tag="IVD66_001207"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HAP6145443.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            1563..1964
                     /gene="ftsL"
                     /locus_tag="IVD66_001208"
     CDS             1563..1964
                     /gene="ftsL"
                     /locus_tag="IVD66_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAP6145444.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            1965..4157
                     /locus_tag="IVD66_001209"
     CDS             1965..4157
                     /locus_tag="IVD66_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAP6145445.1"
                     /translation="MSLKNKIRRFMEKKNLNPINNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            4183..5145
                     /locus_tag="IVD66_001210"
     CDS             4183..5145
                     /locus_tag="IVD66_001210"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HAP6145446.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            5159..6520
                     /locus_tag="IVD66_001211"
     CDS             5159..6520
                     /locus_tag="IVD66_001211"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HAP6145447.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            6546..7634
                     /gene="murG"
                     /locus_tag="IVD66_001212"
     CDS             6546..7634
                     /gene="murG"
                     /locus_tag="IVD66_001212"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HAP6145448.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            7649..8869
                     /locus_tag="IVD66_001213"
     CDS             7649..8869
                     /locus_tag="IVD66_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HAP6145449.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            9025..10350
                     /gene="ftsA"
                     /locus_tag="IVD66_001214"
     CDS             9025..10350
                     /gene="ftsA"
                     /locus_tag="IVD66_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HAP6145450.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            10373..11614
                     /gene="ftsZ"
                     /locus_tag="IVD66_001215"
     CDS             10373..11614
                     /gene="ftsZ"
                     /locus_tag="IVD66_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HAP6145451.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            11631..12308
                     /locus_tag="IVD66_001216"
     CDS             11631..12308
                     /locus_tag="IVD66_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HAP6145452.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            12322..12921
                     /locus_tag="IVD66_001217"
     CDS             12322..12921
                     /locus_tag="IVD66_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HAP6145453.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            12936..13223
                     /locus_tag="IVD66_001218"
     CDS             12936..13223
                     /locus_tag="IVD66_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HAP6145454.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            13272..14054
                     /locus_tag="IVD66_001219"
     CDS             13272..14054
                     /locus_tag="IVD66_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HAP6145455.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            14075..14782
                     /locus_tag="IVD66_001220"
     CDS             14075..14782
                     /locus_tag="IVD66_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HAP6145456.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            15044..17842
                     /gene="ileS"
                     /locus_tag="IVD66_001221"
     CDS             15044..17842
                     /gene="ileS"
                     /locus_tag="IVD66_001221"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HAP6145457.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(17891..19417)
                     /locus_tag="IVD66_001222"
     CDS             complement(17891..19417)
                     /locus_tag="IVD66_001222"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HAP6145458.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(19432..20079)
                     /locus_tag="IVD66_001223"
     CDS             complement(19432..20079)
                     /locus_tag="IVD66_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HAP6145459.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(20263..20592)
                     /locus_tag="IVD66_001224"
     CDS             complement(20263..20592)
                     /locus_tag="IVD66_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HAP6145460.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            20769..21497
                     /gene="sfsA"
                     /locus_tag="IVD66_001225"
     CDS             20769..21497
                     /gene="sfsA"
                     /locus_tag="IVD66_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HAP6145461.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            21513..22526
                     /locus_tag="IVD66_001226"
     CDS             21513..22526
                     /locus_tag="IVD66_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP6145462.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            22526..23803
                     /locus_tag="IVD66_001227"
     CDS             22526..23803
                     /locus_tag="IVD66_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP6145463.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            23866..26568
                     /locus_tag="IVD66_001228"
     CDS             23866..26568
                     /locus_tag="IVD66_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6145464.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            26720..27037
                     /locus_tag="IVD66_001229"
     CDS             26720..27037
                     /locus_tag="IVD66_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6145465.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            27067..27387
                     /locus_tag="IVD66_001230"
     CDS             27067..27387
                     /locus_tag="IVD66_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP6145466.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            27495..28955
                     /locus_tag="IVD66_001231"
     CDS             27495..28955
                     /locus_tag="IVD66_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6145467.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            29023..29244
                     /locus_tag="IVD66_001232"
     CDS             29023..29244
                     /locus_tag="IVD66_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145468.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            29275..29457
                     /locus_tag="IVD66_001233"
     CDS             29275..29457
                     /locus_tag="IVD66_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HAP6145469.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            29457..29870
                     /locus_tag="IVD66_001234"
     CDS             29457..29870
                     /locus_tag="IVD66_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HAP6145470.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            29993..31174
                     /locus_tag="IVD66_001235"
     CDS             29993..31174
                     /locus_tag="IVD66_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6145471.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            31563..31636
                     /locus_tag="IVD66_001236"
     tRNA            31563..31636
                     /locus_tag="IVD66_001236"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31597..31599,aa:Arg,seq:cct)
     gene            complement(31673..31873)
                     /locus_tag="IVD66_001237"
     CDS             complement(31673..31873)
                     /locus_tag="IVD66_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP6145472.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT        10773 a         5504 c         6831 g         8970 t
ORIGIN      
        1 tcttttaaaa ggctttttgc agcttgattt ttaaaaaaat gtttatgaat aaaaaaagtt
       61 gttcccggat ttcccagaaa aggtggtaga aagtggggga ttgtggtaga ctaattttag
      121 ttagtggagg aatggggggg ctttcaatgt tgatgggtga attccaacat aatattgatg
      181 caaaaggacg tttaatcgtg ccctcaaaac ttcgtgaaga acttggcgaa aagtttgttc
      241 tgacacgcgg attggatggc tgtcttttcg gctatccgat gagcgaatgg gaaaatctgg
      301 aagctaaact gaacgaaatg ccgttggcta aaaaagacgc acgtactttt gtgcgattct
      361 tctattcggc tgccactgaa tgcgaacttg ataaacaagg acgaatcaat atacccagca
      421 cgttaagaaa ttatgcagct ttgacaaaag gttgcgtagt catcggtgta tctaaccgaa
      481 ttgaaatttg ggatgagaca cgatggcaag atttttctgc agcagcagaa gagaactttg
      541 acgaaattgc tgaaagtatg attgatttcg gactataaga ataggaagag gctgactaat
      601 gactgaaaca tttcaacact atacagtcat gttgaaagaa acggtagatg gattgaacat
      661 caaaccggat ggcgtttatg tagactgtac actcggcggt gccggacata gtgaatattt
      721 attaagccaa ctaagttcta aagggcatct gtatgcgttt gaccaagatc aaaaagcaat
      781 cgatcacgcc aagctgcgtt tagcttctta tgtcgaacaa ggtatggtca catttatcaa
      841 agcgaacttc agagaattag aagaacgctt gagtgagcat gtagataagg tagacggcat
      901 tttgtatgat ctaggggttt cctctcctca gctagatgaa gcagaacgtg gatttagtta
      961 tcatcaagat gcaccgttgg atatgcgcat ggatcagtca gctcctttat ccgcttatca
     1021 cgtaattaat gaatattcct accatgaatt agtaaagatt ttcttccgct atggcgagga
     1081 gaaattttcc aaacaaattg ctcgtgaaat cgaacgagta cgaaaaacaa aaccaatcca
     1141 aacaactggt gagcttgtcg aaatcattaa acaagtcatc ccagctcccg caagaagaaa
     1201 aggcgggcat cctgcaaaaa gaatttttca agctgtgcgg attgcagtaa atgacgaact
     1261 cggtgccgaa gaggcctctt tagaacaggc aatccggtta ttgaaagtca atggaagaat
     1321 cagcgtaatc acattccatt cattggaaga cagaattgtc aaaagtatgt ttaaagaata
     1381 tagtacggta caagatctac caccgggact tcctgtcata cctgacgaat tccaaccaga
     1441 actgaaagtc attactcgta aaccaatcct tccttcagag gaagagctaa cagaaaacaa
     1501 tcgatcacgc agtgcaaagt tacgtattgc agaaaaaata agaatgaaag aggagtagaa
     1561 tgatggcaga attaaagaaa atgcaagatt acgaatatga tttacctgaa ttggtggatc
     1621 agccggaaca acaaatgcct gattcttctt cgaatcaaga aatcattctt ccacaatcac
     1681 cggcaaaacg attaaagcag atttctgctt tggaaaaaat tgctgtggca agcgtggcga
     1741 ttgctattgt tgctttatgt gttttaacag ttatgctgcg cacaaatatc agcggagctg
     1801 aaaaagaaat cacgtcaata caaacagaaa tcaatgataa aaagcaagaa aaaacgagtt
     1861 tagaacaaga aaaaaacgaa ctttctcgta ctgaacggat taaacaaatc gcagaagaaa
     1921 aaggattgtc tattaatgac gacaatttaa ggaaagtgaa gtaaatgagt cttaaaaata
     1981 aaattcggcg gtttatggaa aagaaaaatc taaatccgat aaacaatcgc aaaaaagtag
     2041 gtatcatttt atttgctacg agtattggat tgttcttttt atttgccgtc cgtttctcgt
     2101 atatcgttat tggaggtcat gttgctggta cctcattagc tgaaaaaaca aaacagttgt
     2161 accaaggaag tgaagtagta aaagcaaaaa gaggaacgat ttatgatcgt aacggtgtgg
     2221 cgctcgcaga agatgcctcc tcttattcaa ttaaagcgat actctcaaaa acatatacct
     2281 ctggggataa aaaactgtat gttgaagaaa agaattttga taaaatagca gaaatcctgc
     2341 ataagaatct ttctatagac aaaaaagatg cactgaatat tttagaggac ggcgcaaaaa
     2401 aagagctgta tcaagttgaa tttggtagct atgggaaaaa tatctcccaa gaaaccaagc
     2461 aaaacatcga agcggacatg aaaaaagaag gtgtcgctgg tctttatttt gtcgaccatc
     2521 aggctcggat gtatccaaat ggcgtctttt cttctcattt tattggatac gcagttccag
     2581 acaaagatga gaatggctta gttggtaaac taggtttgga gtctgcttac aatgatatct
     2641 tgagcggtaa agatggtaag attatttatc aaaaagataa ttttcaaaat cctctgccag
     2701 gtacagtggc agaagaagaa aaagctgtcg acggacaaga tatctacacg actttagaca
     2761 gcagactaca aagttattta gaaacactga tggatcaagt aaatgaagaa tatcagccag
     2821 aagaattgac agcagtcctg atgaaagcaa aaaccggaga aatcttggca atgggacaac
     2881 gacctacttt caatcctgaa acaatggaag gattgactgg aaaagatgct atctggcgta
     2941 atttcttggt acaagatagt tatgaaccag gatcaaccat gaaagttttc actactgcag
     3001 ctgctatcga agaaggagaa ttcaacgaga atgaaacctt ccaatctgga aaaatccaag
     3061 tagaagatgc tacgatcaat gaccatgact ttggtgaaaa aggtgtgctg accatgcgtc
     3121 aagctctttc atggtcaagt aacgtcggga tggtcatact ggaacagcga ttaggcggac
     3181 gatggtataa ctatttacaa aaactgggat ttggacaaag tactcattct ggattagatg
     3241 atgaagtaaa cggtgcttta cctacattaa atattgtcga ccgagcaatg agtgcttatg
     3301 gacaagcggt aggtgtgacg aatttccaaa tgatgaaagc tttcacttct attgcgaata
     3361 acggtacaat gattcaacct cgatatatca gcaaagtggt ggatccccaa actggagaag
     3421 agcgaacaac tcaaacagaa gttctagggc aacctttttc aaaagaaaca acagaaaaag
     3481 tccgtgaata tatgagagat gttgtcgaaa gcgaaaacta cggtagtgct tatggtgtat
     3541 atagtgtacc tggatacaat gtatcggcaa aaaccggaac agcccaaatc gcttctgata
     3601 cagggggata tcaaacagga gatacagcct acctgtattc gattgtggag atggttcctt
     3661 ctgaagatcc agactatgtc ttgtatctaa caatgaaaca ccctaagaca tatgatcgaa
     3721 tggcattggc taaaatcgca aatccattga tgaaacgggc aatggatttt aaagaaactg
     3781 aagaagattc agatacagaa acaaaaacag aaaaagtatc cgtagccgat tatcgtaatc
     3841 ttgaagcgga cgttgcagca gctgatgctc aaaaaagtgg actgcaacct gtagtgatcg
     3901 gtaatggtaa aaaagtacaa aaacaatcta ctgccaacgg tgatcagttg atctctggag
     3961 aaaaactgat cctatatact ggtggtgata agctgatgcc tgacgtaaca ggatggtcaa
     4021 aagcagatat catgaagctg gggaaaatcc tcggtattga agttagtttt gatggagatg
     4081 gttattgtgt caaacaagaa cttgctccat atgaaaaaat cactgaagac aaacttagtt
     4141 ttactttaga agaataagaa gagaaatagg agagaaaaga gcatggaatg gacacaagca
     4201 ttgattccca ttgtcagcag ttgtgcaatg acaattgccg caatgccgct atttattggt
     4261 tattttcaaa tgaaaaagca aggtcaggcg attcgtgagg agggaccaaa gtggcacaat
     4321 agcaaagccg gaactcctac aatgggcggc ttagtgtttc tgatcggctc tattttgaca
     4381 ggaatttggg ttggagcttg gcaaaaacag ctaactccta ctcttttcat cttgcttttt
     4441 gtattagcgt tatacggagt aatcggcttt cttgatgatt ttataaaaat attcaagaaa
     4501 agaaacatgg gactgaactc gaagcagaaa ttgattggac agattctagg gggaatcatc
     4561 ttttatcttg tttaccgttc tgaaggttat ccaggtgtat tgaatttctt cggactagat
     4621 ctacctttag gaatcattta tggtattttc gctctcttct ggcttgttgg attttcaaat
     4681 gcagtaaatc tgacagatgg catcgatgga ttagttgctg gcttaggaag tatctctttt
     4741 gcagcttacg gtctaattgc ttggcatcag catcagtatg atgtattaat catttgctta
     4801 agtgttttag gaggtttact gggtttcttc gtctacaaca gaaaacctgc caagattttt
     4861 atgggagatg tcggttcatt agcgttgggc ggacttttag cggcaatttc tataatgcta
     4921 aaccaagaat ggacattgct tttgattggt ttgatctatg ttatggaaac agcaagtgtg
     4981 atgcttcaag ttacttcctt taagcttaca ggaaaacgaa tttttaaaat gtctccaatt
     5041 catcatcact ttgaaatgtg cggatggtcg gagtggaaga ttgatacagt tttttggttg
     5101 atcagcattg tgacttcgtt gatcacatta tggatcgttt ggtaggagat gacgggaaat
     5161 gaaaaaaata tcaacatatg aaaataagaa agtgcttgtc ttaggactcg caaaaagcgg
     5221 agtaagtgcg gccaaattat tacatgaatt gggcgcactt gtcaccgtta atgatggaaa
     5281 accttttgac gaaaatccgg aagcacaaga gctgctttct ttagggataa aagtaataac
     5341 aggtagtcat ccaatcgaat tgttggatga agaattttca ttgatggtca aaaatccagg
     5401 gattccctac agtcatcctt tagtagcaaa agcccaagaa atgggtattc cggtaattac
     5461 ggaagttgag ctagcttacg aagtagcgga atgcccaatt attgggatta caggaacgaa
     5521 cggaaaaaca acgacaacaa cgatgacagg actactactg aatgcaggag cagatcaagg
     5581 aattgcacgt ttagcgggta atattgggta tccagcaagt ggtgtagcgc aagaagcaaa
     5641 atcagaagat aaaattgtga tggaattgtc tagcttccaa ctcatgggaa tcacagattt
     5701 ccgccctcat atagcggtga ttaccaatat ctatgaagca catattgatt atcatggtac
     5761 aagaaaagaa tatgtcaaag ctaaatggaa ccttcaaaaa aacatgacag aaaaagatta
     5821 tctgatcctt aactggaatc agtcagaact acaagaatta gcgcaaagaa caaaagcacg
     5881 cgtactgcct ttctcgacaa aagaagtgtt ggaagacggt gtgtatgctg acgattactc
     5941 aatatactat aaaaaagaaa aaataatgga aatatctgaa cttggcgtac caggtaagca
     6001 taatgtagaa aatgcactag ctgctatttc tgtagcaaaa ttgtatggta tatcaaatga
     6061 agctatacga gaaacgttgc attttttcca tggcgtacca catcgtacgc aatatgtagg
     6121 agaaatccaa ggcagaaaat tttataatga ttcaaaagca accaatattt tagcgactaa
     6181 aatggctcta agtggatttg aaacgtctaa ggtcgtgtta ttggctggcg gattagacag
     6241 aggaaataca tttgatgaat taattccttc attaaaagga atcaaagcaa tggtcgtatt
     6301 tggccaaaca aaagaaaagt tgatggatgc tggaaaaaaa gcaggcatcg agacaatagt
     6361 aacagccgat tctgtagaac aagcagttcc tttagcatta gaaaacagta cagatggtga
     6421 tgtagtttta ttatcaccag cgaatgccag ctgggatcaa tacccaaatt ttgaaactag
     6481 aggaaacaga ttcatggaag ctgtgaaccg attaaaatag aaaaagtaga agcgagcgat
     6541 aaaaaatgaa aattttggtt acaggcggag gaacaggggg acatatttat ccagctcttg
     6601 cctttgtcaa ttatgtaaag actcaagaac cgaatgctga attcatgtat gtgggagcaa
     6661 aacgaggtct agaaaacaaa atcgtccctg atacaggaat gcctttccat accttggaga
     6721 ttcaaggatt taaacgaaaa atttccatgc ataacatcaa gacggtccga ttgtttctta
     6781 agagtatccg tcaagcaaaa aaaatcctca gtgattttca accagatatc gttatcggta
     6841 ctggaggata tgtttccgga gcggtagtgt acgctgcagc caaaatgggt attccaacag
     6901 ttatccatga acaaaacagt gtaccaggtg ttaccaataa atttttaagc cgatatgtgg
     6961 atcggatcgc tctttcattt aaagatgcgg cttccttttt tcctgaaaac aaagcagttc
     7021 ttgtaggtaa tcctcgagca caagaagtag cagatactaa aaaatcagat attttgaaaa
     7081 catttgattt ggatccagaa aagaaaacag tcttgatttt tggcggtagt caaggagcac
     7141 ttaaaatcaa tcaagcagta tcagtttttt taagtgaata tattccttct tcttaccaag
     7201 ttttgtatgc ttcaggagat agatattatg aagagatcct aaataaaata aatcctgaaa
     7261 tacaaaatat tagtgtccag ccttatatca aaaatatggc agaggtcatg gcttccagtg
     7321 atctgctggt ggggcgtgct ggtgcaactt cgatcgcaga attcacagct ctggggttac
     7381 cggcagtgtt ggttcccagc ccatatgtta cgaatgatca tcagactaaa aatgcaatga
     7441 gtcttgttca cgcaggagca gcaaaaatga ttgcagataa tgaactaaca ggtgaatcac
     7501 taagtcagac agtcaacgaa atcatgggtg atgaagaatt gcaaaagcaa atgtgccgag
     7561 cttctaaaga acaaggaatc cctgatgctt caaaacgtct ttatgactta gtaaaacaaa
     7621 taatcaaaaa ataaaggcgg tggtcttagt gagtaagaaa aaagaaccaa aaaaattgtc
     7681 tcatccgtct tctgatgaaa acaatttgac tccttggcaa aaggctaacc gaaaatatct
     7741 ggcagaacaa gagatgaaaa accaagagcc aaaaaaagaa gacataacat tagatacacc
     7801 cctttcagat tctgaagaag aaaaaacggt tcaagaggaa cagcaagaag aaagccagtc
     7861 cgagaaaaaa atcgaatttt ttgaagagat caagcaaaag aaaaacggtg gaccatataa
     7921 cggttctttt ttgaaccggc tgcccaattt aaaaagtcaa cggcacaaag tactatttcg
     7981 tcggttagct ttgatcatca ctgtattggg tataccgctg atttttttga tctattatgt
     8041 ttctccttat agcaaattac aagcagttgc agtatcaggc aataagacag tcaacagcca
     8101 agaaatcatc tctgatacaa aattgtcatt aggagaaaat gtttggggac agtattttca
     8161 tcgatctact tatatcgatc gccttaaaaa agcacagcca agaatcgaaa cagcaaatat
     8221 acatttcaaa gggatgaatg aattcgattt ggatgtaaca gaatataaag agattgcttt
     8281 gatcgcaaaa aacaatcaat actacccagt gattgaaaat ggaacagtat tagatgaaaa
     8341 agtagcaaat cctacaaaaa atctccctat cttggaagag ttcaaagact ctgcaaaaat
     8401 caaagaatta acaaagcaat acaatcagtt atcatcagaa ttacaaaaag caatttctga
     8461 aatcaagtac acgccaagag caagcaataa aaatctgatc caattgaata tgaatgacgg
     8521 caatcaagtt attgtaaata tcaataatct tgcgaaccaa atgaaatatt attcgcaagt
     8581 agccaaagat atggatgaaa aaggtgtgat cgacatggaa gttggtatct tctcgcatcc
     8641 ttacggtagc actcaagaaa cggaagaatc gggccaatcg gaagaaacaa ctgaaagtga
     8701 agaaaatgcg gatcaaacaa acgaatcaag tgaagaggca gaaacgcaaa aagcacaaac
     8761 acctggatcg tctagcacaa acggatcatc tgattcaaat gattcaagtg aaacaagtca
     8821 aatagaagat aatccaagta caactccgtc aagtttaaat gaaaattgat aaaacaactt
     8881 taaaaagtaa gaatgtactt tctaaaaacc agtaatttat ggtagaattg gaagcagtga
     8941 atatatctat taataagtat attttaaaac ggacgctagt tgttcgcttg tatatggaat
     9001 agtaagtagg agggaatccc attcatggca aaaacaggaa tgtatgtagg ccttgatatt
     9061 ggaacgacat ctgttaaagt tgtcgtggct gaatatatcg acagccaaat gaatattatt
     9121 ggagtaggaa acgcaaaatc agaagggatt aaccgaggca ttatcgttga tatcgataaa
     9181 acggtccaag cgatacaacg agcagtacga caagcagaag aaaaagcagg tatccagatc
     9241 aaaggcgtaa gtgtcggttt gccagcaaac atgcttgaag tagaaaattg ccagggaatg
     9301 attgcagtta acggagattc aaaggaaatc accgatgaag atgtcagaaa tgtggcttca
     9361 gctgcccttg ttcgttcaat acctcctgaa cgtcaaatcg tgtcaatatt gccacaagat
     9421 tttactgtcg atgggttcga gggaatcaaa gatcctcgtg gaatgatcgg cgtaagatta
     9481 gaaatgtacg gtctgttgtt tacaggacct aaaacgatca tccataacat acgtaaatgc
     9541 gtggaaaatg ccggattaat cgtcaacgaa atggtgatta ctcctttagc gctgactgaa
     9601 tcaattcttt ctgacggaga aaaagatttt ggtacgatcg tcattgatat gggtggcggc
     9661 caaacaacaa cggctgttat gcatgataag caattgaagt ttaccaatct tgaccaagaa
     9721 ggtggcgaat ttgtcactaa agatatctct attgtattaa atacgtcatt taacaatgca
     9781 gaagcgttga aaataaacta cggggatgca tacccagaac ggacatcacc agatgaagaa
     9841 tttccagtag atgtgattgg tcagtcagaa ccagtgaaag tcgatgaacg ctacttgtca
     9901 gaaattattt cagctcgaat ggaacagatt ttcaacaaag caaaagatgc attggaccaa
     9961 atcgaagcat tagagttgcc aggtggcgtc gtattgacag gcggagctgc tagtcttcct
    10021 ggtgttgtgg acttggcaca agaaatcttc ggcgtaaatg taaaattgta tgttccaaat
    10081 cacatggggc tgagaaaccc ggtatttaca aatgtaataa gtatcgtgga ttattcagca
    10141 aacttgagtg aagtgtatca attggcaaaa attgctgtta cgggtgaaac ctcagcagct
    10201 cgtcaaatgg tagttgaaca agaaacaaca aacacatatg agagctatga agcacctgaa
    10261 gaaacaatct acgatgagcc ggaaccaaaa gagtccggag aaaatgtaaa aaataaaatc
    10321 aagggtttct ttacaaatat ttttgattaa ttcatcctgg gaggaataag atatggaatt
    10381 ctcaattgat aataatatca atgacggcgc agtaatcaaa gtcatcggag tcggtggtgg
    10441 cggtggaaat gctgtaaacc gaatgattga agaaaacgtt aaaggtgttg aattcattac
    10501 agccaacaca gacgtgcaag cattaaaaaa ttcaaaagct gaaacagtta tccaattagg
    10561 ccccaaatat actcgtggtt taggtgctgg ttctcagcca gaagttggac aaaaagcggc
    10621 agaagaaagt gaacaatcct tacgcgaagc tttagacggt gcagatatga ttttcatcac
    10681 tgcaggaatg ggtggaggaa ccggtacagg tgctgcacca atcgttgcag gtatcgcgaa
    10741 agaattgggc gcattgactg ttggtgtcgt gacacgtcca ttcacttttg aaggaccgaa
    10801 acgtggccgt tttgctgcag aaggtatcgc tcgtttgaaa gaaaatgtgg atacattatt
    10861 aattatctca aataaccgtt tattagaagt tgtagataaa aagacaccga tgcttgaagc
    10921 tttccgtgaa gcagataatg ttttacgaca aggtgtacaa ggtatctctg atttgatcac
    10981 agcgccaggt tacgttaacc ttgactttgc tgacgtgaaa acagtgatgg aaaaccaagg
    11041 tacagcattg atggggatcg gtgtggctag tggagaagat cgcgtagtag aagcaacgaa
    11101 aaaagcaatc tcctctccat tgcttgaaac atctattgat ggagctgaac aagtacttct
    11161 taacatcaca ggcggtttgg atatgacatt gttcgaagca caagatgctt cagatatcgt
    11221 agcaaatgca gcaactggcg atgtaaatat cattctaggt acatctatca atgaagaaat
    11281 gggcgatgaa atccgtgtga cggtcatcgc aacaggtatc gatgaatcaa aaaaggaacg
    11341 caagtctagc cgaccagcta gacaagcaca aatgcaatca cctgctcaaa agactgtatt
    11401 agatatggat caagctaaac caacttcttc agaagaagaa aacagttttg gcgattggga
    11461 tatcagacgt gaacaaaatg ttcgtcctag agttgatgat tccaattttg acaatatcga
    11521 aaaaaaagaa tttgatacat tcaaccgcga agaaacaaaa tctcatggcg atgatgaatt
    11581 aaatacgcca ccgtttttcc gtcgtaaaaa ataaaggaga ggaagagcac atgattgctg
    11641 acaacttgca gaaaatcaag caagaaattc aggattcgtg tgctcttgtt catcgtgatc
    11701 cgaaagaagt tacattagta gctgtaacaa aatctgttga atccgctcaa gctgaagaat
    11761 tggttagagc tggcgttatg aattgtgcag aaaaccgagt agataaatta ttagaaaaga
    11821 aacaagattt atttgatttt cctgaaataa agtggcattt aattggtaat ttacagcgca
    11881 gaaaggtaaa attgattgta aatgaaattg attactttca tgcgttggac agtttaagat
    11941 tagcagaaga aatccagaag cggttagaga aagaattatc ctgttttatt gaagtaaatg
    12001 tttctggtga ggaatcaaaa catggaattt caccagatga gcttttaccg tttgtggaat
    12061 ctttagctgc ctgcacaaaa atcaaggttg ttgggttgat gactatggcg cctaaagaag
    12121 cttctgatga gcaaatccat aaagtgtttg gtacgctgaa agaattgcgt gatcttgttc
    12181 aagcaaaagg ttatgcccat gcaccatgta gtgaattaag tatggggatg agtcaagact
    12241 ttcaaattgc gattgaagaa ggtgcaacat ttatccgtgt aggaacagcg ctattcaaag
    12301 acgaataaag gaggaacaaa aatgccgctt ttaaacagag gagcaattgc taattttttc
    12361 ggattagctg atgaggaaga gtacgaatac caagattatc ctgaaacaac aaaaaaggct
    12421 gtacagccaa ctaaaaaaaa tacaacacag aatcaatcaa ctcattctgt atctgctgcg
    12481 aatactcatg aaaaacaaaa aacggcgact tcacgtcctg taacgcatga aagtattcag
    12541 ccggctgaaa agaaaaaagt aattgaacta catcaatcac ctacaaaaac tgtagcgaaa
    12601 gaaagaacag cttcaagaac ctctacacaa cctaaagcaa atcttgctgg aaaaatcact
    12661 gtaatggaac caagagctta ttctgaagct atggcgattg ctaaacgaat cattgctgga
    12721 gaagcaacct tagtgaattt tcatttagta gaagaaaaac aagcgagaag aatcgttgat
    12781 tttctaacag gaacagttta tgcactagat ggagatatca aacgtgttgg agatgagatt
    12841 tttctttgta caccgactgg gatggagatt gacagttcaa ccgctcaatc ttttgcagat
    12901 gcgaatttgt ttgatctgta agaggaggaa ctacgattta tactattgca ctattacttc
    12961 atttacttca acgggcagcc tatttctata gcattatctt gatggtatat gcattgctct
    13021 cttggtttcc aggcgggtat caatcagggc taggacgatt attagctaag atctgcgaac
    13081 cgtatatcag tttgttcgat cgtctgcctt tgaggattgg acccttggat ttcacaattt
    13141 taggggcaat cctgatcttg aacttagccg tacaaggttt agcacagatc gttatatgga
    13201 taactgtcca tttagtttat tgattgaagc aacaaaatct ttattctcag aatagatagg
    13261 aggggaaaat tttggatgca aatgtatacc agcactttcg ggcagatgaa cgtacattta
    13321 tcgattcggt aggcgattgg attgaacagg ttcaaggaca atatgcaccc tatctgaccg
    13381 aatttcttga cccaagacaa tcctatattt tagaaacact gattcgacaa agcagtgatt
    13441 tgcgtttcat gttttatggc ggatatgaac aggcagaaag aaaaagatgt ttgattttcc
    13501 ccgattatta cgaacctgta gaggaagatt ttgaaacagc attgtatgaa atccattatc
    13561 ctagcaaatt tgccagccta agtcatggga aaatccttgg aactttagtg ggaacgggga
    13621 tcaaacgctc ttactttggc gatatcatct cggacggtga tcgctggcaa gtatttattg
    13681 caaatgaggt ggatcatttt gttgctgcac aagtaacaaa gattggaaag gttgctgtac
    13741 gcttggaacc aatcaaatac acagaaatga ttatgccgaa agatagctgg acacaagaaa
    13801 gaggaacagt tagttccatg cgactagaca gtgtgatctc tgagatttat aatatttcca
    13861 gacagcggtc caagcagctg atcgaagctg gtaaagtaaa agtgaactgg acagaaaata
    13921 caagacctga ttttgtactt gaactattag atattatttc agtcagaggt tatggcagag
    13981 tccagatcca agaacttgag gggaagacga aaaaagaaaa gtacagggta ctgttcggtg
    14041 tattacgtaa ataaaataaa aaggtggttt actcatggct ttaactccat tagatatcca
    14101 aaataagaca ttcccgacaa aaatgcgggg atataatcaa gacgaagtag atgatttctt
    14161 agatttagtt gttcgtgact atgaggaatt gactcaaaga aatcgagaat tagaaaaagc
    14221 agtcaaacat tctgaagaaa aacttgagta cttcaatgaa ttaaaagatg ctttgaacca
    14281 atcaatcatc gtagctcaag atacggctga taaagtaaaa acaagtgcaa gcaaggaatc
    14341 cgaagtgatc gttacttctg cacaaaacaa agcagatgag ttagttgcga acgctgaaaa
    14401 acgtgcacat caattaacaa ctgatgcaga agaaaaagca agaaaaatct tgacagatgc
    14461 aacagaaaaa gcaagacagc ttgcgacaga aactgaagat cttaagaaaa aaacacgagt
    14521 attccatcaa cgtatcagct tgatgcttga gtctcaatta gaacaagtga aaagtccgga
    14581 atgggatgaa attttacaac cattctccag ctacgtgact gacagccatg aagtgatcaa
    14641 agaagtttta gcaaaacagc ttgacaatga aaatgatact gatgtaaact cagacacagg
    14701 agtcatagaa gcacctatga cggcatttga tacacaggct attgatatct cgatcgtgcc
    14761 tggtgaaaat gaaaacgagt agaacagaaa agcactttgt tattcttaaa gcgagccgat
    14821 gagagtggaa gttcggtaag acactgcatg gtgaaagatc ctctacttga gacctgcttt
    14881 tccgaaatta gagtaagaag cagcggctga cctcgttatt ggtcacagag agtttgcact
    14941 agatagatgc aactaaattt gggtggtacc acggcatgtt cgtcccttgc ggctgaacat
    15001 gcttttttgt gtccggaaaa caaataaagg agtgtatggt tgaatgaaaa tgaaagaaac
    15061 cttgcaatta ggaaaaacaa aattccctat gcgtggtaat ttgccaaacc gagaaggcga
    15121 gtggcaaaaa gaatgggaag aaaatcgaat ctaccaaaaa agacaagagt tgaacgaagg
    15181 aaaacctagc tttgttcttc atgatggacc tccatatgcc aatggtaata tccatttagg
    15241 acattcattg aataaaatca gtaaagacat tatcattcgt tcaaaatcaa tgtctggcta
    15301 tcgtgcacca tatgttccag gatgggatac acatggattg ccgattgaac aagtattggc
    15361 taataaaggc gtgaaacgta aagaaatgtc catggcagaa tacttggaaa aatgtcgtga
    15421 atatgcactt tcccaagtag ataagcaacg agcagatttc aaacgcctag gagttgcagg
    15481 agattgggaa catccttatg ttacattaga tccttcttat gaagctgcac aagtacgcgt
    15541 atttggtaaa atggctgaaa aaggctatat ttacaaagga ttgaaaccaa tttactggtc
    15601 tccgtcaagt gagtcttctt tagcggaagc tgaaattgaa tataaagatg taaaatctcc
    15661 atctattttt gtagctttca atgtcaaaga cggcaaagat attcttgatg aagatacagc
    15721 ttttgtcatt tggacgacaa caccatggac attgccagca aaccaaggta ttgctgtaaa
    15781 tccaaaattt acgtatgtat tggtggaagc cgatggccgt aagtttgtcg tagcgaaaga
    15841 tttgctagaa acagtccaat cagaaatcgg ttgggaaaat gtaacagttc taaaagaatt
    15901 tgctggacaa gaaatggaat atatgactgc aagtcatcca ttctatgaac gtgaatcact
    15961 tgtgatttta ggcgatcatg ttactttaga cgctggtact ggattagtcc atactgctcc
    16021 aggacatggg gaagatgact atatcgctgg tagcaaatat aaactatctg tagtgtcacc
    16081 tgtagactca aaaggattgt ttacagaaga agcacctgga tttgaaggta tcttttatga
    16141 caaagcaaat cctatgatca ctgatctatt aaaagaaaaa ggagctttgc tgaagctaga
    16201 tttctttact catagttatc ctcacgattg gcggacgaaa aagcctgtga tctatcgggc
    16261 aactccacaa tggtttgcat ctatcgataa attccgtcag aatattttgg atgaagtaga
    16321 aaaagtagag tgggttatcc catggggtaa aacacgtttg tataatatga tccgtgaccg
    16381 cggcgattgg gtaatttccc gtcagcgtgc atggggagta ccacttccga ttttctatgc
    16441 tgaaaatgga gaagcaatca tcacaccaga aacaatcgaa catgtggcaa aattatttgc
    16501 tgaacatgga tcaattatct ggtttgaaaa agaagcgaaa gaacttcttc ctgaaggatt
    16561 tacccaccca ggttctccta atggcgaatt tacaaaagaa aaagatatca tggatgtctg
    16621 gtttgattct ggttcttctc atgaagctgt tttacgtcag cgaccagaat tatcattccc
    16681 agcagatatg tatttagaag gatcagacca atatcgtggc tggttcaact caagtatcac
    16741 gactagtgtg gctatcaatg gtgtagcacc atacaaatca gttatttctc aaggatttgc
    16801 tttagatggt gaaggccgta agatgagtaa atctttagga aacatcattg caccagaaaa
    16861 agtgatcaaa caatttggtg cagatatcct tcgcttatgg gtatctagtg tagattatga
    16921 agcagatgtt cgtgtttcta tggatatctt aagtcaagtg gcagaagtat atcgtaaaat
    16981 cagaaatacg atgcgtttct tattagcgaa tacagaagat ttcgatccta aaaaagatac
    17041 tgtttcgtac aatgatttac gttctgtaga caaatatatg accgttcgat tgaaccaagt
    17101 aatcaaagaa atccgagaag aagggtacga caaatataac ttcatgcata tttaccgtac
    17161 agttatgaac ttcttgacgg ttgatctatc gtcattctac ctggattttg ctaaagatgt
    17221 agtttatatt gaagcagaag atgattatca acgtcgttgc atgcaaactg ttttctatca
    17281 aacagctgta gctttgacaa aattattgac tcctatcatt ccgcatacag cagaagaaat
    17341 ctggtcattc ctgaaagaag aagaggagta cgttcagtta agcgagtttc ctggttatga
    17401 agagtttgca aaccaagaag aattgatgga tacctggact gctttcatgg acttccgtga
    17461 taatgtctta aaagcattgg aagaagcaag aaacagcaaa ttgattggta aatctttgga
    17521 agcaaaacta actgtttatc caaaacaaca agttcgtgaa atgttaaaag ctttggatgc
    17581 agatattgca caattattga tcgtttcacc agactacttt gaagttatgg cagcagatga
    17641 acaagtgcca gataacgcta tggtatttga tgatgttgct attacagtgg aaaaagcaga
    17701 cggggaaact tgcgatcgct gtcgccaagt tcgtaaagat gtaggagtag atgaaaaact
    17761 tcctcatcta tgcggtcgtt gtgcaaaaat cgttgaagac ttctatcctg aagctgtagc
    17821 tgaaggattc gaagaaaagt aaaagggaaa agggggtgtg acatgttctt tgtcacaccc
    17881 ccttttgtta tcaatcgttt aattttccac gttcacgata ccagttatct ggttgccaga
    17941 tccattcgaa tccgtctttt tcaagtagtt cgaaagctgc tttaggtccc attgatccag
    18001 ctttgtagtt gggaaaatcc ggttgtgttt ggtcccaagc ttttcgaatg acatccacga
    18061 tatgccaaga ttgagcgact tcttcccaat gagagaagtt cgttccatca ccattcaacg
    18121 catctaatag taatttttcg taagcttctg ggctattttc aaccatttct gcactatttc
    18181 taaattccaa tttgattggt tccgtttcaa atccttgccc tacttctttc ccattcaagg
    18241 ataaagaaaa tccttcagtt ggctgaatat agatcgttag aacattaggt ggaagtgtcg
    18301 tatcgtcaca tggttcatcg acagatgttt tgaatacatt aacaggaact tgtttgaata
    18361 cgatgttgat ccgagtccct ttttcagtca aacgtttgcc tgtacgtaca tagaaaggaa
    18421 cacctgacca acggaagtta tcgatagtga atttgcctgc gacgaatgtt tcagtctctg
    18481 attgagcatc cactttgtct tcttcgcgat agcccttgaa ttgtacacca tccaattcac
    18541 cttgagcata ttgcccgcga acgaagtttt ctaacacttc ttcttcgtta taaatgcgga
    18601 tagctttcaa tgctttgatc ttttctgtac ggatttcttt ttcggaaaat gctactggcg
    18661 gttccattgc aagtaatgct acaacctgta aaatatgatt ttgcaccatg tctttaagtg
    18721 cgccactatg atcgtagtag cccccgcgat cttctacacc gaggttttcg ccaaaagtaa
    18781 tttggatatt gtcgatatag cgattgttcc attgagcctc aaaaatatta ttggcaaaac
    18841 ggatagctga gatgttttgg atcatttctt ttcctaaata atgatcaatc ctgaaaatat
    18901 cttgttctgg gaatacttct ctgatttgct ggttcaattc aaaagcagac tggtaatcag
    18961 aaccgaacgg tttttctatg atcaaacgat tgaagccatt ttttgtcata atattttgtg
    19021 atttcaaatg agaaacgatc gttccaaaaa attgaggtgc catagccaaa taatagacac
    19081 ggttaccgtt taattgatag tgtccatcta atcggtcaga caattctttt aatgtctgat
    19141 aatgcgttga atcatttaca tcatgggatt gatagtaaaa atggcttgca aaggtagttg
    19201 cttcttcatc tgaaggattc aatgcacgga ttgtttcttt gacaacttca cggtagtgct
    19261 catcgctcca gggacggcga gcggttccga ttacagcaaa atgctcgcct aaatttcctt
    19321 ttctgtaaag gcggaacaaa gacgggtaca atttacgctg ggctaggtca cctgtaccgc
    19381 cgaatatcgt aaacaataca tttttttcat tagacatgtg gatacactcc tttatatttt
    19441 atcgacaaaa atcgtgctgg ccgccttaaa gctgacgggg attttctttc tatcattttg
    19501 gatagtgatc ggtccttcat aagctgcgat gtcaacgatc tcatattctt cgttgatatt
    19561 caggtcaata gtgactaagt aatccaacaa ttctttttca tcaagcactc gtgcgatacg
    19621 cacttttgta ccgacaggat aggactccaa tgtttgtcgg cgttcttcat ggacaacttc
    19681 ctctttttta ggaatcgatc ctccatgagg acaatgttca ggatgattca aatagttttc
    19741 taaatgatct gcaagatgtt ccgaagtcac atgttccaat acttcagcat catcatggac
    19801 ttcattccag ctatagtcta aatgttcaac taaaaaaact tcccataagc gatgtttgcg
    19861 aatcagactg ctagcttttt gcagtccgct tgcagtcaat tgtacacctt gataagggga
    19921 atgttctaca agctcttctt tcacaagttt agaaatcatt tcactgacag atgcagctga
    19981 gacatctaga ctagatacga tttgtttatt gttgactttc gttgtatctc cacctagttc
    20041 taaaatgatt ttcaaataat cttctcgatt tggtgtcata ttcgatcatc ctttcatggt
    20101 aaaaaaccat cattagtaag tgtaacaaaa aaaacgttaa ttgactattt ttctaaataa
    20161 aaaacaaagg atttttagac gtttttacaa caaaaaacga aagatgatag agaagactca
    20221 ttctttcgtt tataaaggat atatatatac attgggaggg atctattttt cagataacaa
    20281 cttatatgaa gtgtctgcag attcgtcata aagagtttgt tcgggataag aaaagataag
    20341 ataaaaacca tactgatcac gtacgactaa acgatattca tctatttcta ccacagatgt
    20401 gccaagagac tgaccgttga tcaaaaacgt gtaatcagat gtaatctgta attgttgttt
    20461 ttgctggcta tcactaaaga accatgtacc ttgatacttt gagagtcctt ctgacttttc
    20521 cgcttgtttt ttctttttca agtaaataaa acttgagaga acggtaatga gtgaaccaag
    20581 aaaatagatc atttttttta tcaccaaatc actcctttat gagaaaataa tcgcatagac
    20641 atattctttc ttctttattt cattgtaccg aataaaagct aaaatttctc taagactttc
    20701 gactggtttt tttactgttt ttctacaaat tatgatagga tacatagtag gaagaaaggt
    20761 gacataattt gaagtatcag caagtggaaa tagctttttt tattgaccgc ccgaatcggt
    20821 ttatagcaca ttgtatgaaa aaagacggag aaataattat tgcgcatgtc aaaaatacag
    20881 gtagaggaaa agaggtcctg ataccaggcg ctgaagtggc tattgtattt gctcctggac
    20941 ctaaacggaa aaccgcctat gatctgattg ctgtaaaaaa gaagggtgac tggtttaata
    21001 tcgatagtca attgcctaat cggctggcaa ttgatggtat tttagacggc acgatccttt
    21061 taccaggatt aactggtcca tttacggtat acaagcgtga agtaacttat cttcactcca
    21121 aatttgatat ttatttagag acggtggtcg gacaaaaagc atttgttgaa gtcaaaggta
    21181 tgacacttga aaataaagcg attggtgctt ttcctgatgc gcccacactc agaggattga
    21241 aacatatagg agaattaacg tatgccgcac aagatggtta tgccgcttat gtcttgttta
    21301 ttgctcagtt cgaacatctt catctggcaa cgatccatga agaaatgcaa ccagcactag
    21361 ctgatatggt tcgacatgcg cagcaaagcg gagttcaaat cctcgcctat aattgtcaag
    21421 tatcggcaga tgaggtaact gtcaagcagg ccattccatt tgatgtagat atcccttttg
    21481 aagatcctat acaatagaaa gaaggtaaaa taatgatcaa cttaggtatt atcggaacaa
    21541 attggattac tcatcaattt gtccaagcag ctttaagcac aaaaaaatat gaattgacag
    21601 cggtatattc tagacatttg gaaaaagcac aggaatttgg ttctcattat gaaggggata
    21661 tcgaattcgc aacagatttg aagacttttt tcaatattac tcatatggac accatttata
    21721 ttgcttctcc gaatagtctt cactttagtc aagctaagca agcaattttg gcaggaaaaa
    21781 atgtgatagt tgaaaagcca gctttttcga cgccaaaaga aatggatgaa atcatccatt
    21841 tggcaaatga acacaatgtg tatttttttg aagcagcaag aaatatccat gaatcaggtt
    21901 ttaaaaagat tgccgattac ttaccattaa aagacgagat aatcggtgca aatttcagct
    21961 atatgaaata ttcttcgcgc tatgaccaag tattagatgg agaagaaccg aatatcttct
    22021 cgactcattt ctcaggtggt gcattgatgg atttaggtgt ttaccttgta tatgcagctg
    22081 ttgcttggtt tggaatgcca aaagaagtcc attatttccc aagaaagatt tctactggtg
    22141 tagatggtct tggatggggg atcttacgtt atgagaattt tgatgtatcg atccagccag
    22201 gtaaaatcgg tgattcttat ttaccgtcag agatttattt tgactcagga acgctagtga
    22261 tgaatggagt caatgcaatt gaacaagcac aatttcatga tcgcgcgcat aaagaaatca
    22321 ttgatttggc ggtaacagct gcagaaaatc caatggcaga tgaagcagag gattttgcca
    22381 atgtcatggc tcatccgaaa gatccagctt ggggattgtt gtatgaagag tggatcgagc
    22441 tagctagaaa tgtgaaccaa gtgatttatg atttaagaaa aaatggcggc atcaaattcg
    22501 atgcagataa tgaggaagat ttttaatgaa cgaatttgta caagtatttc ccgaaaattg
    22561 gcagaaaaaa tatgaggata aagggtttat ctcaccttct cttattcaac gagcagtttt
    22621 tcagccacta agtaataaac aaagtatagt agcggtttct cctacaggtt caggtaaaac
    22681 actggcttat ctttggcctc tactactaaa cgtggaacca ggtgaagcaa gtgcgttggt
    22741 catttttgct tcttctcaag aactagctat tcaagtagca gatgttgcac gtgaatgggg
    22801 aaaagacaaa gagttgaaag tccaatcttt ggtgggcgga gccaacgtca aacgtcagat
    22861 tgagggtttg aaggaaaaac cagaaatctt gattggtaca ccaggaagaa tattggaatt
    22921 gatgaaagca aaaaaaataa aagcacatca agtgaaaaca atggtatttg atgaagcaga
    22981 ccagctattt gacgctggga acagccaaat cattgatcaa attcttcatc aagctccaac
    23041 agagtatcag ctagcttttt tttcagcgac agcagatcgt tcccttgaaa gcattgaaaa
    23101 aatcactggg aaaacgtttg agacaattga cgtgacagca gaggacgatt ctcgaaaagg
    23161 actgagacat tactttttac gtgtaccgat acgaaagaaa gatgactact tgagacgtct
    23221 cacgcatata gaagattttc atggtctgat tttctttaat caactgactg aattaggcgt
    23281 aatggaagaa aaattgctgt atagaggtgt accggtagga agtctggcct ctgatcagaa
    23341 caagctactc cgaaaagcag cgctagaaca attcaaaaag aaaatggtca gagcactttt
    23401 gaccacagat gtggcggcta gaggtttaga tattacaggt cttccttatg tagtgaatgc
    23461 agaagttccg ttaagtgaag aagcttattt gcatcgttcg ggaagaactg gtcgaatggg
    23521 taatgaagga atagtaatta cactcgtaca agataataat ctaagagatt taaaacggct
    23581 tttacgtcca tcaaatataa cacttgaaga gattttttta tacggaggta agctgcaaac
    23641 tgagcagcca accaaagaag atgcagctcc tgcagtaaat aaaaagtatg cgaaaacttt
    23701 ttctggaaag gagcagaacc cagaatataa caaagaaaaa ataagaaaaa aagttaaaaa
    23761 taaatcaaaa aaagagagaa ataaaggagc aaggcgcaaa taagcgcctt tttatgctat
    23821 gattatgaaa acgggaacaa aattggttgc cagaggaggg gttatgtgaa agaacgtcaa
    23881 gaagagatct tgcagctatt gacagaaaac caacaaggat tgacagcaag tgatgtagct
    23941 gagcgcttaa ctatcgatcg aagcaatgca agccgatatt taagtgaact atacaaggcc
    24001 catcatattg taaaaaccgc tggccgacca gtcgtttact ctttgccaac ggaaaagtca
    24061 aaatctgatg aagtgcatgt cgactcttct acgcaagtga cttttgaaac actcgttgga
    24121 gaaaatgatt ctttaaaagt cagcatacag caggcaaaag ctgcgattct ttatccaccg
    24181 cgggggttgc atacgattat ttttggagaa actggtacag ggaagtcgat gtttgctgaa
    24241 tgtatgtatc attttgcaat cgattcagag atgctttctg cagatgcgcc atttgtttct
    24301 ttcaattgtg cggattatgc tcaaaatccg caactgctct ttggacacat ctttgggatc
    24361 aaaaaagggg cttacacagg agcagctcaa gatagtcccg gtctaatagc caaagcagac
    24421 ggcggtatat tgtttttaga tgagatccac cgtttaccgc cggaagggca ggaaatgctg
    24481 tttactttca ttgataaagg tatttaccgt ccgcttggag aaagtgcaca agtacatgaa
    24541 gcatctgttc agatcattgg ggcgacgact gaatcttcag aaagtttctt atctacgttc
    24601 aatcgacgga ttcctatggc aatcaccttg ccgaatcttg cttcacgttc actggatgag
    24661 cgttatgaaa tcatctctct ttttatcaaa caagaagcga atcgtttgaa tcaacgtatc
    24721 gatatcgaaa aagaagcgat tcttgccttc atgctttatg atgcggaagg aaatatcggt
    24781 caagtgaaac gagacttgaa actagtctgt gcaaaatctt ttttacatta ccgtactcat
    24841 catgagaaaa agctaatcat tcgaaaagaa gaactttccc ttcaagtaca aaaaggatta
    24901 ctgaaaatca aggaaatacc ggaacgtctc gaccgattca tggacagcaa aagtcagtat
    24961 ttgacatttg aaccaggatt tgctgatgtt gtctggtcac aagatccaga acgaaacatg
    25021 caggtctata acgatattga ggaaaaagtc acttctcttt ccgaaaccgg tgtggagaac
    25081 attgatctag agaccctcat ttcaaaagat gtggatgctt atttccagac atatgtcaaa
    25141 gaattgacta aaagttcgat tcccaaagat cttttgccag atgaaatctg gcggttaacc
    25201 aatcaattgt atgatgtggc tgaaaaacgg ttagaccgta tttataatga aaaagctcgt
    25261 tttgcttttg ctttgcatct gcaaagtaca ttggatcgtg tgagagaagg tcatatgatc
    25321 gtccacccag atttgaataa cgtacggaaa aattttaaga gggaattcca ggtagcaatc
    25381 gatctttcaa cgatcattga agaagaagaa caagttgaga ttccttttga tgaaatcggc
    25441 tttattagta tgtttctttc tatcaatcta ggagaaagtg agcctgttaa agaaaacaaa
    25501 gtagatgttc tcatattgat gcacggcaga cagactgctt caagcatgtt ggagatggca
    25561 caagaactat taggaacaaa agtagggaaa gcttttaata tgccactggt tatggaagtt
    25621 caaacaatgt atgaagaagt gttacaatat gtcaaaaact atcaagagca tttgacgaat
    25681 ggcctactct tgttaacaga tatgggatca ttaaacacct tcagtgattt gatttatgaa
    25741 gagactggca ttcggacgaa agctatcacg atgacaagta ccatgattgt gatagaagcg
    25801 atacggatgg caagtgttgg aagaagctta gaagatattt atcaaaatat ccagctttcc
    25861 tttgaatcga tcgtacgtga tcagttcaaa gcggaaaagt ctgaaacttt acagcgtaaa
    25921 aaagccgtaa tcgtgacatg ctttactggt gaaggagtag ctgccaaatt atatcagcgt
    25981 attatgccag tgattaatca aaataaggta gaactgatcc agatgcagtt tttagaacgt
    26041 gaatcattca aaaaacacat cgatgcctta ttggaagaat atgagatcaa agcaattgcg
    26101 ggaacagttg atgttgatta tcaaaatatc ccattttttt cagcctatga cgtttttgat
    26161 gatgaaaaac taaatatttt aaagcgtata gctgatgatg agatcccgac agctaaaatt
    26221 gtcgattcac ttgctggatc attaagcgat gtcttttcta ttgatgaact gatccgttca
    26281 ttgcaaaaga cagttcagca gatccagacc gatttgtcga ttatcgtgga acctggagta
    26341 gatactggaa tcgttatcca tttagccttc atgttagacg gattgatcaa acaagaaagc
    26401 catcggcaat ttgagaaact gtctattttc tcaaaaattt atcgtttgga aatggatatc
    26461 gttcgggcaa acttgatggc actagaacga aaatatcagg taaaaattcc agaagatgat
    26521 atcgcatttc ttacacaaat gtttcttgaa aataaaataa aaaaatgaac acactaatca
    26581 tactgtttac acactaaaca tctgtgtgcg cactataaaa aagagctaaa aagcatgaaa
    26641 acgctatttc agctcttttt tttattggca tgcttcttgc gttatataaa agtgtaaaaa
    26701 aataaaagga gtgttaaaaa tggcaaaaaa aacaatcatg ttagtttgtt cagcagggat
    26761 gagtacgagt ttattggtca caaaaatgca aaaagcagca gaagaaaaag ggatggaagc
    26821 cgatattttt gcggtctctg cctcagatgc agataataat ttagaatcta agaatgtcga
    26881 tgtattatta ttaggtcctc aagtacgttt catgaaagct caatttgaac aaaaacttgc
    26941 gcctaaaggt attccattag atgtcatcaa tatgcaagac tatggcatga tgaacggaga
    27001 aaaagttctt gcacaagcag aaaatctaat gaaataaatc aagtatgcag ttgggggtat
    27061 aacaacgtgg aagatcaaca aaatctagaa gccatcatgg ggttaatcat gtttggcggt
    27121 aatgcaaaga gcgatgcaat ggaagcgatt gcggctgcta aaatcggtga ttttgagtta
    27181 gcggatagga aaatcgctga tgcagaagaa tcacttatac aagcgcatca tgcacaaaca
    27241 gacatgttga cacaagaagc acaaggaaat catatgcaag tgacattatt gactgttcac
    27301 agtcaagatc acttaatgac atctattgcg tttactgatt tagcaaaaga aatcatcgaa
    27361 ctttatcgtc gcgtatacag cgaataaata caacttcttt tttgaacgga agaagaaaaa
    27421 tttttgaacg gattttttat tttgttataa ggagaactct ctttatataa aaaacttata
    27481 ggaggaagta aaaaatgaac ggactatcaa gttggatgga gaaatacatc ctgccggttg
    27541 ccgcaaaaat cggagcgcaa aaacatttag ttgctttgcg tgatgctttt atcggcacac
    27601 tgcccgcaac aatggcggga tcagtcgctg taatgatcaa tgcaattatt cgtgatttac
    27661 cgcaacagtt taacagtacc tatgctgaca gtttagcagc agacaaagga atctttgccg
    27721 tattgaatgt catcatcgga atcaatggtt ttgtctggaa cggtacacta gcaatcgccg
    27781 gattgatctt tgccttttct tgggggtata atcttgcccg agcttatgga gtaaatgatc
    27841 tagctggggg gatcgttggt ttagctacct tgattcaagg tatttccttt ggtccagcat
    27901 tatcagcagc attagatgtg aatgttcctt caaatgtcgc agatgcaatc aatagttctg
    27961 agattggtgc aacgattgca gatggcacac tgtcagttgg attatggggt tggctaaaac
    28021 tagatcattt gaatggaaac gcttatttta cagttatgat catgggagct atttcagtca
    28081 ttattttttg taaattgatg cttgccaaca ttacgatcaa aatgcctgat tcagtaccac
    28141 cagcagtatc taaagcattt gcagccattt taccagcgac gatcgcttta tacgtcattg
    28201 ctattatcaa ttatatcgta ggtcgtgtag ctgatgggca actgatcatt gatttggtgc
    28261 aaaaatatat tgcagaacca ttcctaggat tatctcaagg gttgggagca gtattgatcg
    28321 tcacagtatt tgttcaagta ttctggttct ttggtattca tggaccaaat gtattggcac
    28381 cagtgctaga gggaatctgg ggacaagcac aactaatcaa tattgatatt ttccaaaaag
    28441 gttataacgg aaaaactggt acaccagccg tgttagatgc aatcgaagat ggaaaagctt
    28501 atatgtgggt ccgcggatcg ttcgatgctt ttgcatggtt tggcggatca ggcggaacga
    28561 tcgtcttact gatagctatc ttgattttct ctaaacgtgc agattatcta acagtagcta
    28621 aattatccat tgggcctggt atcttcaata tcaacgaacc agtgatgttt ggtctgccaa
    28681 tcgtattgaa tgcaatcatg tttatcccat tcttgattgc tccagtagta gcaacagcaa
    28741 ttggatggac agctacttat cttggcctag tcgctccggt atcgcagcaa gtcacatggg
    28801 tagtaccgcc gttcttattg tcattcttag caacaggagc ggattggcgg gcaccgatcg
    28861 taacattagt atgtatggtc gtgactttct tgatttgggc accatttgtc atctctgcaa
    28921 acaaaatgga ccctgccgca ggcgaacaac aataagatga acgtgaggag cgggacgctt
    28981 taagtttcgt tcctcataat gaattttcta ggaggaactg aaatgattac aattgccagt
    29041 gcaatgcaac aagatgaaat caaagaattg ttagaaggat acaatgaaga aggaatgact
    29101 tttacattta aagaaaaaca aggaatcaag ctgttctttg aaacaagtgc agaagatccg
    29161 gaagttgcgg ctaaaaaagc aaaggaacta atcaaagcac agccttgggg aacagtcctt
    29221 tattttcaat caacagctgt ttagaaaatg gtttaaaaag ataggatggt tgagatgata
    29281 aaaaacggtt tatttttatg tagtattggt tctttgatcg tgttgtatag tttgaatcca
    29341 cattcgcaaa ggtatgattt gtatagtatg gtcacaggtc tttttctaac aggattagga
    29401 atctatttct tcatgaaggg gaaaaaaaga gaagaagcaa aggagaaaaa taactaatgg
    29461 aaatcacgaa aaaattaaat attccagcat cgttttttta cgataaagtt atggactctg
    29521 tccttttcga tgtacgtaaa gcgaccggca aatcagtaac tagaaaacag ctgaaaaatt
    29581 tggagtacgt caaacaattc tcgcaaaata accgggctcg cataaaaatc gaagaagtca
    29641 ttgaaaacca gtcttataag tttcgtacat cgacaacgaa gaatgaattc gtcgttcatt
    29701 atcaaatcaa accattggac gattcgacct gtgaggttca ttacacagaa aaaatggagt
    29761 cttatggcat gcttcaaaag ttgaatgata tgcttttagg aacaatcttg atgtatttta
    29821 aacggagacg tttcaaaaaa atgctagata tgatcgaagc aacgtattaa atcaatgaaa
    29881 catggtacta tttagttatt gaaaaatgaa gtaagctaga aggaattttt cataggaaga
    29941 tagatctttc ctgcgaatcc tcactagctt ttttgtagga aggggcagca aaatgacaaa
    30001 caaagtaaga gagctaggtg tatcttcgat tgaggaaatg tttgatttag ccacttatgc
    30061 atttaatggg gcagatacac ctgaaaggcg agaacgtttt cgtacacttg cggagaattc
    30121 ttggaattac ggattttttg atgaggagga tcggctaaca agtcaagtca tggcgacccc
    30181 ttttccagtg aatttttacg gacaagagta cctaatggcc ggcattggct atgttgcttc
    30241 ttatccagaa gcaaggggac aaggcgggat caatcagatc atggaaaaga tccttgaaga
    30301 ttgccgtgat cgtaaagtaa gcttatctta tctggcgcca ttctcctatc ccttctatcg
    30361 gcgctatggc tatgaacaat catttgataa aatcagttat caactaaaca gtcgtgatgt
    30421 gccgtttatc aaaaaaaaat ctggaaaaat aaagcgtatg gattttgaag atgcaaaagc
    30481 tgcaatcaga agaatttatg aacagatgcc ggaaaaccaa cgagctggtc tgaagcgcga
    30541 agactggtgg tatacgtata aattcaagca aaaaggcaat taccagtttg ctttgcattt
    30601 tgatgataat gaggaagcaa cgggatatat cgtttatcag cttgcaacgt cttcctttat
    30661 tattgcggag tggggatttt tggatcatga tgctttttgc agccttgttc gcttcgtaag
    30721 ttctcacaat ggtgcttttg aaacatttga atattcatgc ggctacggcg gtaatgatca
    30781 aaattatcta ttagaaaatc catttgcttc tgtaatgatc acaccttata tgatggcgag
    30841 gatcgtagat atttctttgt ttttggaaaa ttatccattt aaaaagagac aagctgcatt
    30901 tgccctacaa atagaagaag atcattatgc gaaatggaat gaaggaatcg tggaagtaac
    30961 aatcgaaaat ggaaaaaatc atctctcaaa agtagaacaa acaaaactcc caatcgttcg
    31021 aggaagtatc caacatatca cgcagctatt attagggtat cgtaaagtgg aagagttggt
    31081 attccaagaa agaatacagg tgacaaaaga atatgaagaa acgttaagct caatcttgcc
    31141 acagcaacag ccaattctta atgactattt ttgataaaaa acgggtgatg acaatatttt
    31201 tgtcaccacc cttttgtttt tcatttggca tttgaaggaa aatgttaaag taaatcctct
    31261 tttttcgtaa atttgaattt tttgttttct tttgttttag ggttttcttt tttgtggtct
    31321 tggattgctt ctttcgtaat cttttcccga ttttttttag atgaatctaa gcgttctgcg
    31381 tatacttttt cttttggctt atcattcatt ggaaaggacc tccctacatt atttcattct
    31441 acctctagtt tatcatctgt taaggactag tggaaacgtt ttgcctaact tataagctga
    31501 tttttttagc agataagctt gcaagtaaaa aacaaacaag ctacaattga tttattgaaa
    31561 ttgttcctgt agctcagtag gatagagcaa tcgcctccta agcgataggt cgctggttca
    31621 attccagtca ggaacgtaca aataacccct gtatcctttg cggtacaggg ggttattttg
    31681 tataagtaga cattgtagtt tctaaactgc tatgtcctaa acgtttcgat acgctaagta
    31741 tatttactcc ttgataaagt aaaatagatg catgcgtatg tcttagtcca tcaataaaca
    31801 gtcgaagaga aaatagggaa aaattgatta ctaaagaaaa acttactagg tcgacggtgt
    31861 agttgatttt catacttcaa tagattcgaa ttaaacgatt tcgattggct tataccagtc
    31921 ctatccaacg aaagatatat cgttcttaac tctagcggta taacttgaag ctttacgtaa
    31981 agccaatggg aatgaactgg agatgacttt ttattatttt tagtaatagc tgatgggtta
    32041 atacttacaa ctttcctttt caaagtacca tataaaaa
//
LOCUS       DACBZK010000025        30886 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.025, whole genome shotgun sequence.
ACCESSION   DACBZK010000025 DACBZK010000000
VERSION     DACBZK010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30886
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.025"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(27..725)
                     /locus_tag="IVD66_001238"
     CDS             complement(27..725)
                     /locus_tag="IVD66_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobyric acid synthase"
                     /protein_id="HAP6145473.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(718..2070)
                     /locus_tag="IVD66_001239"
     CDS             complement(718..2070)
                     /locus_tag="IVD66_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HAP6145474.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2293..3693)
                     /locus_tag="IVD66_001240"
     CDS             complement(2293..3693)
                     /locus_tag="IVD66_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HAP6145475.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3854..4591
                     /locus_tag="IVD66_001241"
     CDS             3854..4591
                     /locus_tag="IVD66_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HAP6145476.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4716..5195
                     /locus_tag="IVD66_001242"
     CDS             4716..5195
                     /locus_tag="IVD66_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HAP6145477.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5192..5959
                     /locus_tag="IVD66_001243"
     CDS             5192..5959
                     /locus_tag="IVD66_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145478.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6189..6758
                     /gene="lepB"
                     /locus_tag="IVD66_001244"
     CDS             6189..6758
                     /gene="lepB"
                     /locus_tag="IVD66_001244"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP6145479.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6862..7464)
                     /locus_tag="IVD66_001245"
     CDS             complement(6862..7464)
                     /locus_tag="IVD66_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP6145480.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7570..8039
                     /locus_tag="IVD66_001246"
                     /pseudo
     CDS             7570..8039
                     /locus_tag="IVD66_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8145..8729
                     /locus_tag="IVD66_001247"
     CDS             8145..8729
                     /locus_tag="IVD66_001247"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAP6145481.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8732..9805
                     /gene="prfA"
                     /locus_tag="IVD66_001248"
     CDS             8732..9805
                     /gene="prfA"
                     /locus_tag="IVD66_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HAP6145482.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9798..10637
                     /gene="prmC"
                     /locus_tag="IVD66_001249"
     CDS             9798..10637
                     /gene="prmC"
                     /locus_tag="IVD66_001249"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HAP6145483.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10630..10809
                     /locus_tag="IVD66_001250"
     CDS             10630..10809
                     /locus_tag="IVD66_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145484.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10831..11856
                     /locus_tag="IVD66_001251"
     CDS             10831..11856
                     /locus_tag="IVD66_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HAP6145485.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12031..13275
                     /locus_tag="IVD66_001252"
     CDS             12031..13275
                     /locus_tag="IVD66_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HAP6145486.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13428..14375
                     /locus_tag="IVD66_001253"
     CDS             13428..14375
                     /locus_tag="IVD66_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP6145487.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14509..15138
                     /gene="upp"
                     /locus_tag="IVD66_001254"
     CDS             14509..15138
                     /gene="upp"
                     /locus_tag="IVD66_001254"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HAP6145488.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPGGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15277..15519)
                     /locus_tag="IVD66_001255"
     CDS             complement(15277..15519)
                     /locus_tag="IVD66_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145489.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15640..15712
                     /locus_tag="IVD66_001256"
     tRNA            15640..15712
                     /locus_tag="IVD66_001256"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15673..15675,aa:Thr,seq:cgt)
     gene            complement(15831..16469)
                     /locus_tag="IVD66_001257"
     CDS             complement(15831..16469)
                     /locus_tag="IVD66_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP6145490.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(16592..17224)
                     /locus_tag="IVD66_001258"
     CDS             complement(16592..17224)
                     /locus_tag="IVD66_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAP6145491.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            17575..17874
                     /locus_tag="IVD66_001259"
     CDS             17575..17874
                     /locus_tag="IVD66_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP6145492.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            18369..20534
                     /gene="acm"
                     /locus_tag="IVD66_001260"
     CDS             18369..20534
                     /gene="acm"
                     /locus_tag="IVD66_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HAP6145493.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(20806..21291)
                     /locus_tag="IVD66_001261"
     CDS             complement(20806..21291)
                     /locus_tag="IVD66_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HAP6145494.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     gene            21771..22412
                     /locus_tag="IVD66_001262"
     CDS             21771..22412
                     /locus_tag="IVD66_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP6145495.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     gene            22431..23066
                     /locus_tag="IVD66_001263"
     CDS             22431..23066
                     /locus_tag="IVD66_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP6145496.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            23084..23899
                     /locus_tag="IVD66_001264"
     CDS             23084..23899
                     /locus_tag="IVD66_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6145497.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            24218..25654
                     /locus_tag="IVD66_001265"
     CDS             24218..25654
                     /locus_tag="IVD66_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP6145498.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            25843..28290
                     /locus_tag="IVD66_001266"
     CDS             25843..28290
                     /locus_tag="IVD66_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAP6145499.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            28520..29587
                     /gene="rlmN"
                     /locus_tag="IVD66_001267"
     CDS             28520..29587
                     /gene="rlmN"
                     /locus_tag="IVD66_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAP6145500.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(29780..30883)
                     /locus_tag="IVD66_001268"
     CDS             complement(29780..30883)
                     /locus_tag="IVD66_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP6145501.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
BASE COUNT        10591 a         5287 c         6283 g         8725 t
ORIGIN      
        1 ttgtcacatt cccctttttc gaataactag gctgtttgtc cttcaagata gggcagatcc
       61 aattctttac cgtaacgttg ttctaaagct aggcggatca aacgagctgc caggttctca
      121 tttcttgcaa ggataggtcc atggaaataa gaaccgaaga catttcggta aatgacacct
      181 tcagattggt cttcaccatt atttccttga ccttgtacca ctttccccaa aggtcgttca
      241 ccttcaccta agaaagtccg accattgtgg ttttcaaatc cataataagt ttcattgaat
      301 tcttcgttat ggataacgat atcaccgata aaccggttat tttcctgact taacgtgtag
      361 tgatccagtg cactgattcc ttggatcttt tctccattag ctcccatgta gtagtgacct
      421 agcaattggt agccaccaca aatggctaac atgacgccat cattttcgat atagttgatc
      481 aaagaatctt tctttttctg gatgtctttt gaaatgatta attgctcaaa gtcttgacca
      541 ccgccaaaga aaaccaagtc atatttatca gcatcaaaag gttcatgtat actaacgatc
      601 tccgtatggc aagaaacccc cattttttct gctatatatt tcaacatcaa aaggtttccg
      661 ttatcaccat atgtgttcat caaatttcca taaaggtggg cgatattgag ttcataatta
      721 gccacggttc attcctcctt tgataaatcc ttgagcagct agttctttac gaagctgcaa
      781 tacagcagtg taagtagcta aaatatagac atgctcagtt ggcaattctt tgattttttc
      841 gattacttct ggtaattctt ttgtttctgt caatttattt tctggaatcc cggcaacttt
      901 tagacgtaaa gtcatatctg tatgacggtc tcctccagaa ataacagctg ggatatccat
      961 atcggcaaag ttttcaaaat taccatccca aatccagctg acatcgattc cgtctgcgta
     1021 attggcattt aataaagcca ctaaagaaaa tggataagga gctagaccaa tcatatcgat
     1081 tacttgattg atacctacag gatttttgac aagtactaat gtacattttt tcccattgat
     1141 attgatgact tcttgtcggc cgaatacttt ctcgtcatat cctaaacctt gtttgatttt
     1201 atcaggatcg acattgaagt actctgccac tgcagtagct gctaaagcat tgtagacatt
     1261 atacataccg ccaacttcga ttccgtattc atgaccatcg atcacgaaat ctgctgacac
     1321 attgtccatc cgtaccatat cagttaatcg ataatccaat tcaggacgtt tgaagtcaca
     1381 atttggacag taatatttcc ctaagtttgc ataagtgatc attttataat gcaagatgtg
     1441 atgacaattt ggacataaga caccgtctgt attgtaatga gccatttgtt cacgatcttc
     1501 ttcatggtca aagccataat attttctagg attgactgtt tcgatagaat tgaagattgg
     1561 tgaatcaccg ttactgataa tcgttgcatt tggtgacttt gcggcaccgt ctacaatcat
     1621 tttataggtc gtatagattt ctccataccg atccatttga tcacggaaaa tatttgtaaa
     1681 taagaacagt tctggtttca tatattctgt gactttgctc aaacttgctt catctatttc
     1741 taggacagca aactttttct gtcctttttt tggttttgcc tgcaagaaag tcgatacaat
     1801 tccctgtacc atattcgcac cagtagggtt ggttagaact tcatcgaatt gctggcgcaa
     1861 aatattgact gttaaagcgg tagtcaatgt tttaccgttt gttccggtga caacgacgac
     1921 ttggtagtct tttgccaaac tatctagtat atgtggatcg actttcagcg ctagtttacc
     1981 tggtaaactt gatccgcctt taaaaaaagt ttttaatgcc cattgcgacg tttttccaac
     2041 tgcaatcgca aaatgactgc gtattcccat tatgtaacct ccaaaaacga tttgctgacg
     2101 aataaattca actaatcata ccatatgttg aaaaaaaggt taaattgctt ttcttattct
     2161 taagaaaagg ttacggctga aagtgcatga aatcggacaa aatcgcatga tttaacaaaa
     2221 aaacagcttg aaacaaaatg attgtttcaa gctgctgtga ttttattatt ccctcttacc
     2281 tatattccca ttttaaccga taataatttt ctcgcttgga tattcatagc ctagatctcg
     2341 tgtttctttt ggcacgaata acatcaatgt atatagcatt ccgatccgcc caataaacat
     2401 cagtgtagca atcgtgattt tgcccacaac agacaagtct ccggtaatcc ctaaagataa
     2461 accagttgtt ccaaacgcag aagttacttc gatgatgatc gagatcagcg tttgttcttc
     2521 tgtagcagat aaaaaaacga tacaaaagaa acacatacca agagaaagca taaagacaac
     2581 gactgatttt cgcacatcat cttgatcgat tctccgtcca aaaatattga tgttatcttc
     2641 acttttgagg aaggaatata gatacaaacc gatgattgct acagtagttg ttcgaatccc
     2701 gccgcctaca gaactaggac tgcatccgat aaacatcagt aaagaaaaaa tgatcagtgt
     2761 tgtgatttga aaatcaccca aatcgtgaat ctgcagacca gcattacgag tcgtaatcga
     2821 ataaaacatc gaattgatcc atttgacact catattggaa tcttggaata aatggtcctt
     2881 ttccaataga taaatcaaga cagttcccga aacaaacaag ataacaaaag ctaacacagc
     2941 taatttggta aacaaggaaa aacgaaacgg aagcttcgca ttggaacgtt tgtataatag
     3001 ccattcccgg cactccatca atacaggaaa accaattcct ccgacaaaaa tcaaaaacat
     3061 gatcaggatc aagaaaaaat agtcatgtgc aaagggcttg atggaatccc cagtgacgtc
     3121 aaacccagag ttcgtgacag ccgatatcgc ctgataaaaa ccgtaaaaaa cggcatcacg
     3181 ccaacgatca aaatagcctc tgtaataaaa ataaatagaa aagaatgtcc caaaaagtaa
     3241 ttgaaaccag attaaaatag caaaagtgat ccgaatcagt cggacgatac cagacaaacg
     3301 cggttgattc atatccgtca tgatcagctg tcgctgtttc agtgtgatcc gtcgtttaga
     3361 aaaaatgaca aaagcagtag aaatcatcat gatccccaaa ccaccaactt gaaataatat
     3421 ttccagcagt ataataccgt tatcattgaa cacagaattg atatcaaaag tcgatagtcc
     3481 agtcacactc actgtactga ttgccatgaa cagcatgtcc acaaaagaaa catggctatc
     3541 tggttcgcga aaaatcggca tataaaatag aacgagtgat aagaccgtca tcaatatata
     3601 ataaaaaacg atgatttgga tcgatgagaa atgattggca gcaaacttct gtcctcgccg
     3661 ctgcagcctt cgaaagaata aatcaacatg cacagtacta tcctcctgac aatagtcgtt
     3721 tctaccagta tacaagggga attaggaata ctcaaagaaa ttatcaaaca gataacaata
     3781 cagctttcga ttaaaataga aatggcttat aataaggaaa atcctagaaa aaagaaggag
     3841 gaggaataac aaattgatta atgctcaaca aatcgtagaa aaaatgaaaa atcaaaaaat
     3901 aaattatgat acagttctga aaaaaatgat catgcaatgg gagaaagaag aagtaaagcc
     3961 taagatatta atacatacat gctgtgctcc ttgcagtacg cacacattgg aattcatgtc
     4021 tcaatatgca gagatcacgt tatttttttc aaattcgaat attcatccta aaagtgagta
     4081 tttgcgaaga ttacatgaac aaaaacgatt tgtagaccaa tttaatgaga aaactgacca
     4141 tcatgttgcg ctaatcgttg atgaataccg tccaaatgaa ttcaccaaaa tggttttaac
     4201 aaaccatctt gaaaacgaaa aagaaggtgg tgctcgctgc agtgcatgct tcaatatgcg
     4261 attagatctt gttgcgcaaa aagcgcaaga actaggatac gattactttg gaagtgccct
     4321 gaccatctcg ccaaagaaaa atgcagcttt gatcaatcag atcggaatgg atatccaaaa
     4381 gatttacggg acacaatact tgccaagtga tttcaagaaa aacaaaggct atgaacgctc
     4441 tttgcaaatg tgcaaagagt atgatattta tcgccaatgt tattgtggtt gcgtgttcgc
     4501 tgccaagcag caaggatgcg atctgaaaga aatcaatcgg gaagcaaaag cttacttaaa
     4561 aacatcaacc gtagtttttg aggaaaatta aagaaatctt tcggaaaaac gtaagaaaaa
     4621 aataaagaat ttatggtaga aataaggtag actgtataat ttgtccgtag taaagtaagg
     4681 aaacaagaat aaatttcaat gaaggaagag ataagatgcg aaaagtagca cctattttga
     4741 agccaatcgc tgtattaaca atctcgacga ttgtcgcgac tactacaggt attgtgaata
     4801 gttccagcta ccgtgcacca agttcaagtt ctagtactgt agaagaaaca acaccaacta
     4861 cttcagtctc gacatctgaa ccaacaacaa cggaaagttt gaatgaaacc actacgacaa
     4921 gtacatggga cgatacaaca actagttcgt cgtatgatga gacatataca actgacagct
     4981 caagcgaaac aagtaatacg gtaccagatg gcactccatc ggattcaacc aatccaagta
     5041 caagtccgga tacaagtgct agctccgaaa cgataccaag cagtacgact gtagatgata
     5101 acacgcaaaa tgatgatgca gcacgtacag cacagcaaaa ccaagattca ggaaataccc
     5161 aaacgtataa ccagcaagca ggtgattctc aatgacattt ttactagacc ttatcaacgg
     5221 ggtgcataaa ttccttggct atttagacat cagtcctaaa tatcttaacc gtggatatac
     5281 gattttaagt gtgattccca cgctttattt attgagaatt gtttatggac tttggcaaaa
     5341 ccaaaactat cttcaatttt tcttatatgg acttgcattt ctagtgcttg tttattttac
     5401 tgttttaaat gtattttatt actttttaga taaaaacacg aaagccgatg tcactcagct
     5461 ttttgtgaag tatttacctg atgaagcgtt caacatccag acagaagaat cgatagataa
     5521 tggaaattcg atcgataaag tgaatacaca agaggtcatg gtttcttatg acgaagatta
     5581 tcaattgaaa ttagccgaga atatgcggta tttgattgga aatggtgaga tcaaaacaaa
     5641 tgaactcggt cgcatggatg gatttctggt cgatagaaat acattgtatc cttattacta
     5701 tgtcaagaaa acaggagaga aagagtatgt tctaaatatt ggacgaagct actcggacat
     5761 ggaaaaagta gggaccattc gacttgactc aacagaagac acattggaac ctgtcggatt
     5821 gttcatcgtc ggcggtgatt ttgtcaaaga cgggttacgc tatcatgagc cttatcgtct
     5881 gaaattgatt gcaaaaaagg cacagtcgca ggaagaacca gtggtttata gtcgtagcca
     5941 aagaagaaga cattcataat gtgatgaaac gccgtgtatc agtggttgcg ataaaaacgt
     6001 ttattcggaa taagggggat gtgacacgtc ttttgtcacg ttcctttttt atataacgag
     6061 aaagataaga cgaacacatc acttattctt tcctttcatt tataaacatt gtagaataaa
     6121 gaaagtacaa cgaagtattg tgaaaaaacg taataaataa cgaggaaaat acaagtagga
     6181 ggtaagctgt gaaagaattt ttgaaaaatt gggggatttt gatccttgta ttagcggcta
     6241 ttttattagc tagagtgtac gtgtttacac cagttactgt aaacgggcat tcgatggacc
     6301 ctacattaag tgatggacaa cgattgattt catctaagat ctcaaactat gaacgaatgg
     6361 atattattac tacaaaggaa ccgggggatg aagaacggat gattgttaaa cggatcatcg
     6421 gtatgcctgg agatacagtc aagatggaaa atgaccagtt gaccattaat ggcaaaaagt
     6481 atgatgaacc ttatctggat gagttcaaaa aagaattttc agaagataag ttacaaggag
     6541 aatatgctta tagctcagga ttccaagcac aagcagaaag ttcatccacc tttacgagtg
     6601 actttgaata tactgtgcca aaaggaaagt atcttgttct aggcgataac cgcttgattt
     6661 caaaagacag ccgaatgttt gggttagtcg acaaagatat gatccaagga aaagttgttt
     6721 tccgttattg gcctctttca gaaattaaaa tcatgtgatg aaaaaataaa aagaagctgt
     6781 gacatgtttt ttgtcacagc ttctttttcc gaaaattcct tcttatttct tggagttgct
     6841 cacttttttt gcaatctcat tttaagcttt ttggctgatg gataagaaaa gcgaagcgtt
     6901 tttgttcata aatagctttt ccccacgatg gaaggtatga ctagtagcag agacaaagcc
     6961 cgttttttcc aatcgattat tcaattcttc ttggctaaag ccattatgga ctttcggatg
     7021 actaatttgt tcattcttgt caaagtctac gatgatcaat tgaccgccag gagctaaaat
     7081 ttcataaagt tttgtaagaa tattctccgt atcaggaatg tgtaaaagta caagtgatag
     7141 aaggatgaga ttagcttgga cagcaggaaa ttcgacagaa gcatcagcgt ggatcgttcg
     7201 gacatttttc agatctgctg cttggatctt ttcttctgcc attttcagca tagtttctga
     7261 agcatcggca atgatcagtt ctttgaatct ttccgcaagc ggtaaactaa caagcccagt
     7321 tccgcctccg taatccagca ggactttttg gtggctgtcg cgcggtagat aagtagttag
     7381 ttcttcgcga ataatcttgg ctaatgcttg acggtcaggg gaatcataat ggttagcgat
     7441 ggaatcaaaa atattttttg tcatcaaata gctccttacg taaaactttg aaattttaac
     7501 ttattatagc acgtgaaaag aaagaaagca tgctatactc aattcaaaaa gggagaatct
     7561 agaaagaata tgccgatatc gtttgtaaaa gatagagagg aaaaaggaaa gtgtgtccga
     7621 gaaatattac tagacttgcc tgagtggttt gggcttcctg aatcaacgga aaaatatatc
     7681 gaggaatcaa gtaaactacc tttatggtgt gaaaaaagaa aagaagaata tttaggcttt
     7741 atcactcttt cacagacaag tgaagatact gccgaaatct attctattgt atgggaataa
     7801 aaaaagacta tcatcaccaa ggattaggaa caaaactttt taaagaagca gaaggttacg
     7861 cagcaaaaca ttacaaatat ttgcaagtga agactgtaga cgaggggcac tactctatat
     7921 atgatcaaac tatttgtttc tacgaatcat taggattttc aaggttggaa gtttttccaa
     7981 atttatggga tgaatggaac ccatgtttag ttcttgtcaa aaaattggaa caaaagtgag
     8041 caatagattt aatactaatc tgtgcttgat gaaaattctc actgtaaaaa atgctgaaaa
     8101 tcaagtataa taccatagga acaaactgga aggtgaaaaa gagcatggca caactatttt
     8161 ttaagtatgg cgcaatgaat agcggcaaga cgatcgagat cctaaaagtc gcacataatt
     8221 atgaagaaca aaataagcca gttgtcttaa tgacaagcgg tattgataca agagatggtt
     8281 taggcgttgt ttcaagccga atcggactga aacgtaatgc gatgccgata tttgaagaaa
     8341 cagacgtatt tgacgtaatt cagaaaatgg aaagcaaacc ctattgtgtg ctgatcgatg
     8401 aagcgcaatt cttaaaaaag aaacatgtca ttgcttttac gagaattgtg gacgaattgg
     8461 atattccggt tatggcattt ggtttgaaaa atgattttcg aaacgagtta tttgaaggat
     8521 caaaatattt attgctttat gcagacaaaa tcgaagaaat gaaaacaatc tgttggttct
     8581 gccacaaaaa agcaatcatg aatttacatt atattgatgg aaaccctgtt tatgaaggcg
     8641 atcaagtgca aattggcgga aatgaagctt attaccccgt ttgtcgaaaa cattactttc
     8701 acccatcaat gattacagaa ggagaataag catgtacgat caattacaag caattgaaga
     8761 ccgttatgaa gagcttggag aacttttaag tgacccagaa gtgatttctg atacaaagcg
     8821 ttttatgcag ctttcaaaag aagaagcaaa cacgcgcgaa acagtcgaag tttatcgtcg
     8881 ttataaagaa gtagtacaag gaatcaccga tacagaagaa ctgcttggtg aaaaactgga
     8941 tgatgaaatg gctgaactag caaaagaaga attatctgaa ttaaaaaaag aaaaagaagt
     9001 cttagaagaa aaaatcaaga tcttgctttt accaaaagat ccaaatgacg ataaaaatat
     9061 catcatggaa atccgtggag cagcaggcgg agacgaagca gcattattcg ctggcgatct
     9121 tttcaatatg taccaaaagt atgctgaagc acaaggctgg aaaacagaag tgatggaagc
     9181 taacgttacc ggaatcggtg gatataaaga agtgatcatg atgatcaccg gagacaacgt
     9241 atattcgaaa ttaaaatatg aaagtggtgc gcaccgcgtc cagcgtgttc cttcaactga
     9301 atcgcaaggg cgtatccata cttccaccgc aacagttgtc gtgatgccag aagctgaaga
     9361 agtagagatc gatattgaag acaaagatat ccgtacagat atctatcatg cttcaggtgc
     9421 tggcggacag cacgtcaata aaacagcatc tgctgtacgt ttgactcact taccaacagg
     9481 gatcgttgtt gctatgcaag atgaacgttc tcaaatcaag aaccgtgaaa aagcaatgaa
     9541 aatcttgcgt gctcgtgtgt acgataagat ccagcaagaa gcacaaagcg agtatgatgc
     9601 caatcgaaaa tcagcagtcg gaactgggga tcgttcagaa cggatccgga cgtataattt
     9661 cccgcaaaat cgtgtgactg atcatcgtat cggattaact atccaaaaat tagatcagat
     9721 tttagcaggg aaattagatg agatcgttga tgcattgatc atgtatgatc aaacatcaaa
     9781 actggaagct atgcaaaatg ggtaaaatga cctatcgaga agtcctgtca cgggcttctt
     9841 cttttttaga ggatcatggg aaagaagcat atagtatcca atttttattt ttggaacgaa
     9901 aacaatggaa aaaacttgat tggctccttc atatgaacga agagatttca gaagaagaac
     9961 agcggttgat cgaaaccgat ctgcgacttc tgcttgcaga tcatccacct cagtatttgc
    10021 taggatatgc agatttttat gatcatcggt taaaggtaac tgaagcaaca ctgatccctc
    10081 gaccagaaac agaggagtta gtcgaatggt gtttagacga gacgcctggt gtaccgttag
    10141 aagtgataga tattgggaca gggactggag caattgctat tagtttgaaa gcagcaagaa
    10201 aaaattggca tatatctgct gtggatcttt cagaagaagc attagaagta gcgaaagaaa
    10261 atgctcagaa agaaggaacg aaaatcagtt tttatcatgg agatacatta ggaccagtaa
    10321 tggatcagca atttgatgtg attatttcta atccgccgta catcagtcgg aatgaatggg
    10381 aactgatgga tgaaagtgtc cggtcattcg aacctaaaat ggcccttttt gctgagaacg
    10441 atggattagc tatttatgaa aaaatagcag ttgaagcacc aagcgtacta aaatcaaatg
    10501 gaaagatttt tttagaaatc ggatttcgcc aaggtgaagc agtaaaaaaa atatttcagc
    10561 aagcatttcc agataaaaaa gtggcgataa aaaaggatct ttttggcaat gaacgaatga
    10621 tccaagttta tggttgaagt tgtggatgaa aaatttttta tttgtttttt tattataaaa
    10681 aaacacttat ttgacaagga tgtaaacgac tttttggttt atcaacaagt ttatccacta
    10741 ttgacaaata gattatccac aaacagtgga aaacttgagg ataaactcag acaaaataag
    10801 aatgtatgaa aaaggggttg tggataaact gtggaaacga aacgatatga tgaaacagaa
    10861 ttgcaagagg cagccgaagc actgaaagaa ggagaacttg ttgcttttcc taccgaaaca
    10921 gtatacggat tgggcgccaa cgctctttta ccaaacgctg tcaagaaagt gttttctgta
    10981 aaagggagac cgcaagataa tccattaatc gtccatgtcg cctcttttga acaagtaaaa
    11041 gagtatgtgg acaactttca tccggcagca gagaagattg tgaagaactt ctggcctgga
    11101 ccattaactt tgatatttaa gatcaaaaaa gacactttgc cctcagttgt gacgggagga
    11161 ttatccacag ctgcatttcg tataccggat aacaaaaaaa cactagaagt aatcgaactt
    11221 tccggtgttc cgcttgtcgg tccaagtgca aatacgtcgg gaaaaccaag tccaacgact
    11281 gcagatcatg tatatcatga tctacaagga aaaattaccg ggattattga tgatggagct
    11341 acgcgaattg gtgtagaatc cactgttctt gatttaagtg atccaacagc catgcctatg
    11401 attttacgac caggtgcagt aacgaaagaa caaatcgaag cagtcatcga atctcctgtt
    11461 gctattgatc agcatcttgt aaaagaaaat gaaacaccaa aagcccctgg gatgaaatac
    11521 aaacactact cacccgatac acgtgttctg atggtcagag atggcgattg gtcaactgca
    11581 gttcaatggg caaaaaataa gaagatccgt gcaggtgtca tagcaagccc cgaaattgcg
    11641 gatcaagtgc ggacagatac tgcagctgtt tatatgtata acgacaactc agtagaagcg
    11701 gcggctaaag gattgtttgc aggtctaaga ggattagatg aaccaacact tggattagat
    11761 ttgatttttg tacaagtgta tccagaaact ggattgggga atgcttacat gaatcgcttg
    11821 aaaaaagcag caggacaaaa ttattttgaa aaatgatcaa ttggttattg tcgcattctt
    11881 ttagtatgat acaatgctat caagtaaatc ttctatcagt gaacgaaaaa ctaagcgtaa
    11941 ctaatcgtaa tagaagagat acgaatattt ggcaatttgt ttttgatggg aaaaataaaa
    12001 ttgtaggaaa ataaaaagga gctgttgttt gtggtagatt acaaaacgtt tgaccctgat
    12061 ctttgggctg cgatcgccaa agaagaagaa agacaagaac ataatttgga gctgattgcc
    12121 tctgaaaact ttgtctccga agcagtgatg gctgcacaag gaagtatctt gacaaataaa
    12181 tacgcagaag gttatccagg gcatcgctat tatggtgggt gtgaatttgt cgatatcgtt
    12241 gaaaatttag cgattgaccg tgcaaaagaa ttattcggag cgaaatttgc gaacgtccag
    12301 cctcactccg gctctcaagc caacacggct gcttatctcg ctttggtaga accaggggac
    12361 acgatcttag gaatggatct ttccgcaggc ggacatctaa cacatggatc accagtcaac
    12421 ttcagtggca aaacctatca ctttgttgct tacggtgttg atccgacaac agaagttatt
    12481 gattataatg tggtacgtat tttagctaga aaacatcaac caaaattgat cgtagcaggt
    12541 gccagtgctt acggacgaac gatcgacttt gcgaaattca gagaaatcgc agatgaagta
    12601 ggcgcaaaac tgatggtaga tatggcacat atcgcaggat tagtagcagc aggacttcat
    12661 cctaatccag ttccttatgc agatatcaca acgactacca ctcataaaac attgcgtggc
    12721 cctcgaggcg gcatgatttt gacaaacgat gaagcattag caaaaaaaat aaatagtgcg
    12781 gtatttcctg gtattcaagg cggccctcta gagcatgtga ttgcgggtaa agcagtagca
    12841 ttcaaagaag cattagatcc tgcatttaaa gaatatagtg aacaaatcat cgccaatgca
    12901 aaagcaatgg tcaaagtttt caatcaagca attggaacca gagtcatttc aggggcgaca
    12961 gataatcatc tgatgttgat cgatgttcgc gagttaggta taaatggaaa agaagcagag
    13021 agcattttgg acagtgtgaa tatcactgta aataaaaact cgattccttt tgaaacacta
    13081 agtccattca aaacaagcgg tattcgaatc ggcacgccag caatcactac tcgcgggttc
    13141 aaagaagaag atgctgtaaa agtggctgaa ctagttgtca aagcattaca agcaaaagat
    13201 gataacgctc aactagacga agtcaaaaca ggtgtacgcg aattaactga aaaatttccg
    13261 ttgcataaaa aataaaaatt taaattccat tagtaaacag aaaagttcaa tgttgggctt
    13321 ttctgtttat tttttgggaa aacggattct ttgacaatat cggtgatgct ctctagtata
    13381 tgaggtgtaa ttttagtctt cacactaaat ctcagggagg aaaagtcatg actgatcgta
    13441 tctcgttaga aaaggaagca gtagcattca gtgatgcaaa tgcgcctcat ccgcgtatct
    13501 atgaactagc accggaagaa ggaagagttt tactagaaga agtacaagaa tcacctgtga
    13561 acaaatattc cgtcgatatt gaagacttga tggtggatac tggcgaatgg ggaaaactca
    13621 atattcgtct cgtacgacca gaagggaata tggataaatt accagttatt ttttatattc
    13681 atggagcagg ctgggttttt ggcagtgctc aaacccatga taaattgatc agagaacttg
    13741 cggttcgtac gaattccgtc gttgtctttc cagaatatag tcgatcacca gaagcaaaat
    13801 atccaacagc aattgaacaa aattatgctg tgttgcaaca gctgaataaa ttagccaagt
    13861 caaaaaatct ggatctcgag aatctaatcg ttgcaggaga ttcagtaggt ggtaacatgg
    13921 ctacagtcat gacgatctta acaaaagaac gaaagggcct cccaatatcc aagcaattgc
    13981 tgtattatcc agtcacaaac gctgattttg atacagattc ctatcatgaa ttcggagaaa
    14041 actatttttt gacaagagaa ggaatgatgt ggttttggga ccaatatacg acgaatgaag
    14101 aagagcgtgc tgaaatcaca gcttcgcctt tgagagcaaa tataaatgaa ctaaatgatc
    14161 ttccttcagc aatgatttta acgggagaag cggatgtatt aagagatgaa ggtgaggctt
    14221 atgcgcgcaa acttcgtgat gcaggggttc ctgttacaca agtacgcttc caaggaatca
    14281 tccatgattt tgtcatggta aatgctatgg atcagacaaa ggcaacgcgt gcagcaatgg
    14341 cattatctac ttcttggatc aagaaaaaag aataagcttt gcttgtccgc aggaaaactt
    14401 cttttcaaaa acggattttc ttaggaaaaa tggcgagttt gactagtcaa tcacttgatt
    14461 ttgttttaca attaaaaaga aacgacagaa caaaggagag cttaaaaaat gggcaaattt
    14521 caagtgatcg atcatccatt gattcaacac aaactaacta ttattcggga caaaaactgc
    14581 ggaacaaagg tttttcgtga agtagtcgat gaaatcgcta tgttgatggc atatgaagta
    14641 tcacgggata tgccattgga agacatcgtg atcgaaacac cgatcactga aacaacacaa
    14701 aaaacgttgt ctggtaaaaa agtagcgatt attccaatct tgcgcgcagg tattggaatg
    14761 gttgacggta tcttggaatt gattccagct gctaaagtgg gacatatcgg tctttatcga
    14821 gatgaagaaa cattggaacc acatgaatat ttcgtcaaac ttccagaaga cattgatgca
    14881 cgtcagttgt ttgtagtaga tccaatgttg gcaacaggcg gatcagcaat catggcaatc
    14941 gatgcattga aagaacgtgg cgcgtcgaac attaaatttg tttgtttggt agcagcacct
    15001 gggggagtaa aagctttgca agaagcgcat cctgatattg acatctatac agcttctcta
    15061 gatgaaaaat tgaatgaaca tggttatatc gttcctggac taggggatgc gggtgaccgt
    15121 ttgtttggta caaaataagt aaatacgaaa aagggtgtga cacaactttt gtcacatcct
    15181 tttttggtca tttttaacgt ttgatgcaga acagcttttt cacagctttc gtttgcatat
    15241 aaaaaaacca tcccaaaaat gcagagatgg tcaaattcaa atctttttta gttctttgta
    15301 gttaacgatt actacaccct tactttgcgt catcaagttc gcattttctg cagtttcatc
    15361 aatctcaaca acagcggaat ttttcaattg ctttgaaatc gttccagttt gcgacttgcc
    15421 gtgaattgtg aacattacgt gagtattgat cttgaatttt tcaccaattt ccgatggtac
    15481 gatagttgta tcaaattttc caaaagttgc cattttcata aaacctgcct ttcacatcaa
    15541 ttataccacg ttttatgaaa aatatcatga aattaaacta attttccatc ggactcttta
    15601 caatcagcca aatagagtat ataatttctt ttggataagg ccagcttagc tcagttggta
    15661 gagcaacgca ctcgtaacgc gtaggtcgta ggttcgatcc ctatagctgg cattaaaaga
    15721 gaagacagat atatcaagga tttttaatcc attgatacat ctgtcttttt gtttaaagga
    15781 aataaagtat gctttcttag caatagagca tgtattattt ctataaaaat ttaggagaat
    15841 aaaacgacta gcaatatagc tgtgaaatca aatatcacat gaactgccca acttgtaatg
    15901 atcgagttgc ttttaatggc agcttggttg aataacaatc ttgccacccc ttgtatcaaa
    15961 aggatgtgtg ctacagtgtg taaaatattt ccattatcat aagtactgta atggataaat
    16021 ccaaagatga ttgctgacaa gaaactagcg acaggaatgc tgaacttact agaaaaaata
    16081 gcgagaaaat acactgagaa caattcttct ccaagtatca tgataggcaa aataataaat
    16141 aataacgggc tgaaagcctc atttattgga ttgcctgtta aaccccattt caaaatttgt
    16201 tgcaaaaata ccgagactgc ggcactgatt actacattga taaaaaaata tttggctata
    16261 tttttgacag gagcgacagg tttcgagaac atttttttcg tatctttttt accaaaaaca
    16321 agtgtaaatg ctataaatcc agtgatagtt aaagaaaaaa tgctaataat ggatggcgca
    16381 aatagcaacc ctaacaaacc gagtacaacg acaatagtgc ccaatatccc ttttttaagt
    16441 tctatttttt ttcctaaaat gttattcatg ataataactc ctactattca gtttttgaag
    16501 atagagtcag tatacatgaa gagttaaaat aggcaatgtt tttttatgga tatttgtatt
    16561 gctaaaaatt tatcttatat attcattttg attatactac ttttatttgt aaaaattttc
    16621 tagcaaaacc aagtgcttgc aactgattaa gcgtacaatt ttttagatgt tccgagcgta
    16681 cttcaatcat ttcaaaggag ttgctactta aatcgatatt ttttaaatca gtatcaaaaa
    16741 agctagcatt ttctaaatca ttagtagaaa acattatttt agtgagggaa cagtctacaa
    16801 aatctgcgct tgataagaca gagtgctcaa aggtactttc ttttatgttt gaaccagata
    16861 aatttacata gtccatttta caattctcga ataacgtgtt cccaatataa ctttccatca
    16921 atttagtacc tgttaattta caattgacaa atttcacgcg atgcaacatg ctttttgtca
    16981 atatacagcc tgaaaaatca cagttttcga atatacagtc ggtaatctcc attctttgaa
    17041 aatcattgga agcaaaaaat gcatacttga aaatagattt gtaaataatt ggatggcaga
    17101 ttatttggtt ttcgatgacc tctttttgtg aaaggatatt atacagttca aaatcttcgt
    17161 tttcatagat atgaaaaaag gatcctttat tcaagcttgc ttcattaact ttaggaaaaa
    17221 tcatatttaa ttacctccat tttcataaag tcatattaac aaaagctaaa ccaacttaca
    17281 ttagcagaaa atgagatagg ttttcgcctt tttcgataac gatagtgtcg ctatctcttg
    17341 aaacgttctt agaattgccc tgagagacac aaattaggcg taattctaat aaaaatctta
    17401 gaataaaaat ttttactgat ttaatttaga atgtttttaa aataaaaatc gttgccataa
    17461 cagtgtattg aaaggtttta acaatccagt aatgatttaa aaaaatctag atgtagcgta
    17521 tactttgttt atagaatgta gtgggaagaa atatattttt gggaggaaat cgtgatgtct
    17581 aaaagtgaag aaatagaaaa catggtacta aaattatatg atctcgtttt aaatccagag
    17641 atcaaagaaa aggaacgtat acttttgata gacgcaaaga caggcttaga aaaaggtcag
    17701 tattatccta aagtcataaa taatttggaa cgtagtttac gtccgttagc aatcagggga
    17761 gaattgtcta aaccagtatc accgttttat atggagatat caacaatagg aaaatttgaa
    17821 aaagaattag gtcgaggaat ggcttcggca ccgattactt ttgggcattt ataaaaacga
    17881 gttattcatc tcaatgaatt aaaaagtata gtcaatctca taatgcaggc taggttcatt
    17941 tatttgaaca gagtctgtat ttttttattc taaataaaga aacagatgtt tctttatatt
    18001 gtattttatc ctttaattaa cacaaaaaca gctagtataa actaataatg ttaattaaaa
    18061 gtgtatttta tgaaactatc gttatttatt aatgttgcat ttttgtaagt taaaaattgg
    18121 aaatatagat tgaaaaaatg aaagcaataa gtaaaataaa atgaatatat gcgaaaaaat
    18181 aatttacatt aggaaaaacc ttgtaaaaac agttttttgg catatttatt ttttataaat
    18241 atttgtaaaa taactatcaa ttttttagtt aaaagattgg aaatgagtgg gggaggaatt
    18301 gaagaaagga tttttgagag atgatatagt aggttttatt tttagttaaa ataggggaga
    18361 tagaaaaaat gaaaaagtgt agaaatatta ttttatcaat gttatttatt attactaata
    18421 taacatcact gattcctgtt catgtctatg cggatgcagg cagagatatc agcagtaatg
    18481 tcacttcgtt gaccgtggac ccaacgaata ttacagatgg aggaaacata aaagtaaaat
    18541 tctcgtttga cgaaaaaaaa caaaatatcc aaccaggtga ttatctttgg atcaattggc
    18601 caagtgaagg aaatattcgc ggtgaaggat tccaaaaaga aatcccatta atgattgaaa
    18661 ataaaaatgt tggaacttta acggtcagaa aagattctgc gcaggttgtg tttaatgaaa
    18721 atattaaaaa cctagactca gtagaaggtt gggggcaatt tgagatacag gccagaaacg
    18781 taaccgatac cggtgaagaa aatacgggac cattcaccgt gacgagcggt gataaaacag
    18841 ctactgtaaa tgtgacaaag ccagcttctg gttcttcttc tagcgttttt tattataaaa
    18901 caggagacat gctacctgaa gatactaagc acattcgatg gtttttgaat attaacaata
    18961 acggcactta tgttgaacaa ccagttaaaa tcagtgatga aatccaaagt ggacaaagat
    19021 tagatccaag tacgtttgaa attaatcaaa tacacttagg tgaacagaag gtttatagag
    19081 gagaagaggg aatccaacaa tttttacaag atttccccag cgctacattt aatttttcag
    19141 taactgataa ttacattgaa ataactatac caaaaaactt tgtcaatctt aggaaaataa
    19201 tggtgagtta taagacgatc atagaaaacc cagaacaaat aaattttgag aatcattcgg
    19261 aagcttggtt taaagaattt aataaacctg ctgttgatgg agaaagtttc aatcatacag
    19321 ttaaaaatat ttcagcttct ggtggagtca acggtacagt tagaggcgaa ttgaagattt
    19381 tcaaatatat caatgacaca gagattggta tcccaaatgt gactttcgaa ttaagacgag
    19441 cagatgaaca gcctattcaa ggacagtcta gtatcctgtt gacttcgaat gaacagggag
    19501 aagctagtat caaaggcctg caagtaggag actatgttgt aaaagaaaaa gaagcaccca
    19561 attggattga ttttgatcca ctaagttcaa atgaactcaa attctccata aacgaaaatg
    19621 atacagaggg agtcagttta cctatttata acaagaaaaa ggttacgaac atcacagcaa
    19681 ctaaaatttg gaacggtgga accactccaa gaccgagtat ttattttaaa ttattcagag
    19741 caagtacaaa caattgggaa ccagttcctg atgcagaaac aaaacgatta gacaatggaa
    19801 taacttcagt gacttgggaa gatatccaac agtatgatga tagtggaaac gaatatacgt
    19861 ttaaagtgca agaagtagat caaaacggaa atgattatgt cccttcaggt tatcaaaaaa
    19921 ttgaaaacgg gctagtcgtt acaaatgaga ataaagaagt catttcagtc tcaggacaaa
    19981 aaacatggga agacaatgag aaccaagacg gcaaacgacc gacgacgatc acagtaaatc
    20041 tattagccga cggtcaaccg atccaacaca aagaagtaag tgaaaaagat gattggcgct
    20101 atcgtttcac aaatctgcca aaatacagag acgggcaaga aatcatctat actgtaacgg
    20161 aagacaacgt gcccgaatac agtacgacga ttgacgggta taacatcaaa aacagttata
    20221 caccggaaaa aacaaatata tctataccag gtagccatat aacaccgtgg aaaaattttc
    20281 cagagaagac agagagagag aaaattagaa atctattctc tcaaaaattg caaatatttg
    20341 ctcatacagg agaatccagc gaacaaagaa gcaattatat tagtaagaga gctgtaccta
    20401 aacagataac aaataaatca aaaagcattc ttcctaaaac aagtagtaaa aaatctagtt
    20461 ttgctgtaat cattggttta ttgatagtaa ctatctgtgc tgggatattc ttacaaaaat
    20521 ataaaaaagt ttagttagaa tataatattt tttgttaaat atgactgaaa tcaaaagaat
    20581 aaaattccga tttataatcg aaaaaagaag catttttata tatgcttctt ttttcgtaga
    20641 atcaataaat atggatttgg ctaactatgg aagaatactc gtattagttt tcagcgttca
    20701 tactagttgt tacattgttt gattggccaa aagaatttct gatatatttt gtgctaaata
    20761 aagaaaaaga cgcttgaatt gggaaataag aaaactactc tatcattaca aattttcata
    20821 aactggcaga tgttctaagt aaacaagtat cttttcaaag tcggaaaaat ccataatcaa
    20881 cgtagtggta ttgatatttg gatgaaagcc tacggtatct tgacgatcaa tagcagcatc
    20941 gatcacgact tggatttttt tctctttgtc gtgcatcaat gctaatggag tcactgtacc
    21001 tgctggaacg cctaggaggt caggaagctg ttcttcagaa acaaaagata agcgcttttc
    21061 ttttaattgt tcagctagtt gttttaaatc ggcgtgcttt tcatcaggca agatgacaag
    21121 atagatttgt tttccttttc ttgatttcaa taatagattt tttacttgcg gaccaggtag
    21181 ggaaaaaggg acatttttga ctgacgtaat cgcaggatga tcgacttttt gaaaagagat
    21241 acccagtttt tttagtagtt cataagcttc ttgttcggtt gcacgactca tcgcgcatca
    21301 ccctcctttt tttattagtg tatcataaaa aagagttgac aaatgaaaaa taatcatgta
    21361 aattacacgt aaagttaaaa caaatgacat cgaaaagaag agtagccgtt aggtgttttt
    21421 agagagtctc tggttggtgg aaagaggcag cagttaaccg tgaaacacat cttggagtcg
    21481 attttctgaa gcgtatagta ggaaaatccg gggagcccgt tacagctgcg gtcgttgcta
    21541 gatgaccaga taaggctggc ttttccgtga ggagtcggta aaaaaaggtg gaaccacgtg
    21601 attaacgtcc tttgatcttc ggatcaaagg actttttgtt ttcatctgaa cggcaacgac
    21661 tgtgtgaggt tttttctgca aggaaaaaat aaacagaggt ggaaccacgt ataatacgtc
    21721 ctcttggcat ttgccaagag gattttttta ttttaaagga ggaaaagaag atggagtatt
    21781 tgattgaagt tatgccgcaa ttattagtag gagcactcac aacattgaaa ttatttttat
    21841 ttaccttgat tggctcatta ccattaggga ttgttttagc attaggattg tctttgcatt
    21901 ttaagccgct acgctacttg cttcaaacat atgtatgggt tatgcgggga acaccgctgt
    21961 tgttgcaact gatttttatt ttttatgggt tgccgacgat tgggatcgtt tttgatcgtt
    22021 tcgaagcagc actcattgcc tttatcttaa actatgcagc ttattttgca gagatctttc
    22081 gtggagggat acaatcgatt cctcaaggtc aatatgaagc agcgcaagtt ttgcaattaa
    22141 gtccctttca aacggtgacg aaaatcgtca tcccacaagt gacaaagatt gttttacctt
    22201 ctgtagggaa tgaagttatc aacttggtca aagattcttc cttgatctat atattaggtt
    22261 taggtgacgt aatgcgtgct gggaaaatcg cgatggaacg cgacgcgact ttactgcctt
    22321 tgctaggcgt ggcaatcatc tatcttacat tgactggtat tctaacaatc ataatgaaac
    22381 aagttgaagg aaaattaaat tattaccgct aactgatagg aggaagaaat atgattgaat
    22441 tgaagaaagt gaacaaagca tttggtgaaa aaaaaataat caaagatttg aatctaatca
    22501 ttccagatgg gaaaacatta gctatcgtag gtccttccgg tggcggtaaa accacgcttt
    22561 tacgtatctt ggctggctta gaaagttctg acagcggaga attttattta gacggtgtac
    22621 cgttcaaccc attcgagctt aaaatgaaag aacaagttgt aggagtcgta ttccaagact
    22681 tccagctatt tccacatctg aatatttttg aaaacattac cttagcacca aaaatggtat
    22741 tgaaacagac aaaagaagaa tacaccaaaa aagcagaaga attagcggct tcattaggga
    22801 ttagtgattt attgaatatc tatccttatc agctttctgg cggacaaaaa cagcgggtag
    22861 cgattgccag agcattggct atgaatccac gggtattggc ttatgatgaa ccaacaagtg
    22921 ctttagatcc tgaattacgc cagcaagtcg agcgtttgat cctatcattg aaagaagatg
    22981 gggtaaccca aattattgtc acccatgatt tagtatttgc agaaaatgtc ggtgatcaat
    23041 tactaaaagt ttccccaatt cattaagaaa ggagaagata gagatgaaaa aaaccagttt
    23101 tctattcgct ttgatcgcag gtcttcttct ttttgcaggc tgttcgaaca aaaaaacttc
    23161 agcagataat tgggcgacta tcaacgaaga gaaaaaaatc gttataggtt tagacgatac
    23221 atttgttcct atgggattta gagataaaga cgggaagctc acaggatttg atattgattt
    23281 agccaaagca gtctttgaac aatatgggat tacggtagac tttcagccca ttgactggtc
    23341 aatgaaggaa tttgaactga acaatggaac gatcgatttg atatggaacg gctattccaa
    23401 aacgccggca agagaaaaga aagtgcaatt tacaaaacct tatatggaaa acgatcaagt
    23461 gctgatcaca cctaaagaat caggaatcac aaactttgga caaatgaata ataagagatt
    23521 aggtgcgcaa aatgggtcat ctggttatga tgtatttacg aaacaaccag aagtattaaa
    23581 agagatagtc aaaaaccaag atgctgtttt gtatgatagt tttaatgaag cattgatcga
    23641 tctgaaaagc agacgggtcg atggtctgct gatggataaa gtatacgcag actattattt
    23701 gaaacaaaga aacgaactag aagacttcaa cataacaaaa ggttcttatg agagtgagga
    23761 ttttgcagtt ggtgcacgca agtcagatag tacattagtg aaaaaaatca atgaagccct
    23821 agatcaacta gagaaaacag gtgaattcca aaaaatatcc gataaatggt ttggcgaaga
    23881 tgttacgccg agaaattaac aaatagggga ctgtgacaaa agacgtgtca cagtcccttt
    23941 ttccgaataa acagtgttct cctgccaact ccttgtgact cggagctgaa tggcaggctc
    24001 acaacctctt ggtaaacggt gttcaaaagc cagtttttcg gtattaagcc aaatttatgc
    24061 aaaaatgtag aaagccattt tcacaaaatt tttcttacta ctcgaaacta agcgactttt
    24121 tcacaacctc ctttacataa ttttattttg ttgtggaagg ggtttcgtgt tattctaaaa
    24181 gaggaacgat tgaaggttat aggaaaggaa gagatgaatg gaacacaaag aacttacctc
    24241 atttccaaaa gattttctgt ggggctctgc ttctgcagcg tatcaagtag aaggagcttg
    24301 gcaagaagat gggaaaggag aatcagtctg ggatcgattt gtacggatac ctggaaagac
    24361 atttaaagga acgaacggtg atttggcagt agaccactat catcgttata aagaagatat
    24421 tgctttaatg aaagaacaag gtctgaaagc ttaccgcttc tctgtagctt ggacacggat
    24481 ttttcctaat ggacgaggag aagtcaatca agctgggctc gctttttatg agagattgat
    24541 cgacgaattg attgaaaacg atattgaacc tatgttgact ttatatcatt gggatcttcc
    24601 acaagcattg caagatgaat ataatggttg ggaatcacgt cagatcattg aagatttcac
    24661 tcattatgca gaaacattat ttgaggcatt ccgcgggaaa gtccattact ggattagttt
    24721 gaatgaacaa aatatcttca cttcattagg ttatttgtta gcagcacatc cgccaggtgt
    24781 gacagacccg aaacgaatgt atgaagttaa ccatattgct aatttagcaa atgcatctgt
    24841 catcaataaa tttcacgagt tagaaatgcc tggaaaaatc ggaccaagct ttgcgtatac
    24901 gccaaattat ccaattgaca gtaatcctga aaatgttctg gctgctgaaa atgcagaaga
    24961 cctgatggcc aattattgga tggatgtcta tatgtgggga aaatatccga ttgctgccat
    25021 gaggttctta gaagaaaaag gatgggcacc aacgattgaa gctggcgatg cagaattgct
    25081 agaatctgct aaaccagatt ttcttgggat caattactat caaacggcga cgaatgcatt
    25141 caatccatta aacggagttg gtgctggaaa aatgaatacg acaggaaaaa aaggttcatc
    25201 agaagaaact ggagttcctg gaatgtataa aaaagttgag aatccatttg tcgaacgaac
    25261 aaattgggac tgggagattg acccagaagg attaaggatc ggactgcgtc gtatcacaag
    25321 ccgttaccgc atgccggtac tgattacgga aaatggctta ggagagtatg acaagttgac
    25381 agaagataaa caaatccatg acgactatcg aatcaattac ttacaaagcc acgtcaaagc
    25441 catcaaagaa gcaatttcgg atggagcaga agtcctaggc tattgcacct ggtcttatac
    25501 agatttgctt agctggctga acggttatca aaagcgatat ggatttgtat atgttgatca
    25561 agacgaaaca caagaaggat ctttggaacg atataagaaa gacagttatt actggtacca
    25621 aaaactgatt gaagaaaatg gagagaacct ttagttcaca tacttaaaac aagaaggtac
    25681 ggctggatat ggccgtgcct tttcttgata aaatcattta gaaattaaga aaaactgtaa
    25741 aataagctga aaaatgaaag aaagcgtcag ttctttcaaa caaaacttta gttcccttac
    25801 ttttttttgt ataatgaaac ttgatgaaat gagggataat aaatggcaca aaagaaacgg
    25861 cctactaaaa aaaggaaaaa gacgaaaaaa acgaaaaagc aaaaacagca gcaggaacaa
    25921 atgctgacga ttggtgttgg gtttgccttg attttatttg ctgtcttcgg ctttttaaaa
    25981 ttaggttttt taggaatatt gattgcaaac ggctttcgga tcattgcagg aaatacttac
    26041 caaatcctct gtcttttatt agccgtatta ggattttgga ttgtcattaa gaatacagag
    26101 ttttcaattg gtaaaaaccg acgctggttt ggcggcatac tcttttattt cggtatctta
    26161 ttattgttac atgcccattt atttggcaaa ctccatactg gggaaccaaa tatcatgggg
    26221 acgacatggg atttgttagc cagtgatata aaacaaagtc aagtagacaa taacgttggt
    26281 ggtgggatga ttggagcaat cctttatcat tttacttact tcttgattgc acagcctgga
    26341 agttatttag cagcagtgct attactggca ggaggagcat tcctgttcag taatctggaa
    26401 ggctatcagc tgttaaatgg tatccaatca attggagaac gagtacagga attattggaa
    26461 ggtgatcctg ccaagcaagc tcgaaagcaa gcggcaaagg aagagagaat gaaacagcgc
    26521 gcagaagcga aagaagcaag gcgcttagct gcaaaagaag ctgcagaaaa agaagctgca
    26581 gaatatgaga agaaaaaagc ggtgagccag caaagggaaa atactgctga tgaatggcag
    26641 gaaccagaaa atacagagcc ggagcagcta agttttgttc caatcgacag ttttcaagaa
    26701 aatatccatc ctgcgaatct agagaaacca gtaccagata caccaaaaca gaccaataca
    26761 gcagaaggtt tttcagatga gttgccagag gatgacggta cctcattaga atttgagatt
    26821 gaagcagaac aggaaaatca agactatgaa ttaccgacag ttgatttgct tgattctata
    26881 ccaactgtgg atcaaagtga tgagtataaa aaaattgaaa aaaatatcgg cgtattagaa
    26941 caaactttcc aaagtttcgg tgtcgatgcc aaggtcgtca aagccagctt aggaccatcc
    27001 gtcacaaaat tcgaagtcca gccggctgta ggggtaaaag taagtaaaat tgtgaactta
    27061 acagatgata tcgcgcttgc tttagcggcg aaagatgtcc ggatggaagc accgattcca
    27121 ggtaaatcac tgattggtat tgaagtacca aatggaaaga tcagtatggt ttcctttaga
    27181 gaaatcatcg aagcacaacc aaaccaccca gataaattac tagaagtacc tttaggacgt
    27241 gatgtttctg gacgggtaca aacggctgat ctttcgaaga tgcctcactt actcgtggct
    27301 ggttcgactg gtagtgggaa gtcagtagca attaatggga ttatcacaag tatattaatg
    27361 cgtgctaagc cccatgaagt aaaactgatg atgatcgatc cgaaaatggt tgaattgaat
    27421 atgtacaacg gcatacctca tctgttgacg ccggtcgtga cgaaccctag aaaagcagcg
    27481 caagccttac aaaaagtagt acaagaaatg gaagaacgat atgaaaaatt cgcggcaacc
    27541 ggagtaagaa atatttctgg ttacaatgaa tttgttcaac agaaaaactt ggaaaacgga
    27601 acgaaacatc caaccttacc attcatcgta gtgatcgtag atgaattagc tgatttgatg
    27661 atggtagcca gcaatgaagt tgaagatgcg attattcgtt tagcgcaaat ggctcgggca
    27721 gcggggattc atatgatcct agctactcaa cgtccaagtg tggatgttat cacaggaatc
    27781 atcaaagcaa atgtaccttc cagaatggca tttgcggtat caagcggtac agattctcgg
    27841 acgatcattg attctaatgg ggcagaaaag ctcttagggc gaggagatat gctattcttg
    27901 ccaatgggtg agaataaacc gatccgtgtg caaggagcat tcatttctga ccacgaagta
    27961 gaacgggtcg ttcaatttgt tacagatcag caagaagctc attatgaaga gaaaatgatg
    28021 ccgacagatg aagttgaaac gacaggtgct ccagaacagc cacaagatga gctgtttgaa
    28081 gaagcaaaag cacttgtcgt tgaaatgcaa acggcaagta tttcccttct ccaaagaaga
    28141 tttcggatcg gttacaaccg agcagcacgt ttagtagatg aactggaagc tcatggagtt
    28201 gttggcccgt cagaaggaag caagcctcgg aaagtattca ttgagcagga agaaacatca
    28261 gaaacgttgc cggacgataa tgacatgtaa aacttgtgtg atgaagggtt gaaaaacgaa
    28321 taaccaataa aaagacaagg catgatgata ccaaaagaaa aaatggtttt tttccatctt
    28381 ttctaatacg gtatgatgtc ttgtcttttt agtttttgtg agattaaagt tctattcgat
    28441 ttatttgtga agtattgcat taaggaaatg aatcatgtat agtatgtagc gaaactttga
    28501 gaaaaagagg gaaaatactt tggaaaaaca gtccatttat ggcttgacga atgaagaatt
    28561 aatcaattgg tttatagaaa acggcgagaa aaaattccga gctgcccaag tttgggaatg
    28621 gttgtatcaa aaacgtgtaa gtaatttcac agaaatgacg aatctatcga aacaattgat
    28681 cgaaaaatta tcggagcatt ttatcatcaa tcctctaaaa cagatggtcg tccaagaagc
    28741 ttcggatggt acagtaaaat atttgtttga actccctgat aaaaacatga ttgagactgt
    28801 actgatgaga caagaatatg gcttgtcagt ttgtgtgacg acacaagtag gatgtaatat
    28861 cggctgtacg ttttgtgcaa gcgggctgct caaaaagaac cgtgatctga ctgctggaga
    28921 aattgttgca cagatcatga tggtccaaca ttattttgat gagcgcaatc ttggcgaacg
    28981 cgtttcacat gtcgttgtaa tggggatcgg tgagccattt gataattacg acaatgtaat
    29041 ggactttttg catatcatca atgatgccaa aggattggca attggtgctc ggcacattac
    29101 agtttccact agtggattag cacacaaaat caaggaattc gctaataacg gcttgcaagt
    29161 caatctggct atttccttgc acgcgccgaa taatgaggtg cgaacatcga tcatgcggat
    29221 caaccgaagt ttcccaattg agaaattgat ggaagctgtg gatgagtatt tagagaaaac
    29281 aaaccgtcga atcacgtttg aatatatcat gttgaatcaa gtaaatgata gaccagagca
    29341 tgcgcaacaa ttagcagatc tattaaaaga taagaaaaaa ttagcatatg tcaacttgat
    29401 tccatataat ccagtcagtg aacatgatca atattctcgc agtccaaaag ctgatgtatt
    29461 gagattttat gatgtattga agaaaaacgg cgtaaactgt gtgatacgta aagaacatgg
    29521 tacagatatt gatgcagctt gcggacaatt gcgaagcaag caaatgaaaa aaacagttgc
    29581 caaataatcg tatcctactc gttttttcaa ttaccataaa aggagcagtt ttcttaatta
    29641 aggaactgtt caacttaaat aagagaaaag attctatagc gaaagctata aagctttttt
    29701 tgacaagaaa aaccctcatc aagcaaagaa atgtcctcaa tttgatgaca gcctgcttga
    29761 tgggggtttt agcaattatt taactgattt tcttatatcc ttgctggctt tcttgtgtag
    29821 catgataagt ttctacgtca agaatggcct gtttaaattt ttctcgggtg atttcataag
    29881 gcacatgttt aatatcattt gttgccatgg ctttatctaa gattgcttct aaatcggtcg
    29941 tgacattgag attcatgtcg gttaacgata ctggaagttg gttctttttc ataaacacat
    30001 agattttatc aaacaaatcg aactgctgat ccatcatcaa taaggtcagt acaccataac
    30061 tgacagatgc tccgtgaagg tatccctcca ttttttctag aacagtcgta ccgtaataga
    30121 atgagtgtgc catagcagaa ttatagttat tgttaactaa aacagaaacc aatccggtag
    30181 taacaatgat atccgaaacg acttgttcaa ttgcatatga gggacgatcg tcggcactat
    30241 ctttcaatgc ttgcgtacca taagtcaaga gacgatcaat gcacattttt ccgatttgga
    30301 ttcctaatct atccgtgtag cctagatcat cgccacgagc agaaaaagta gattcgactt
    30361 ctttggataa agcatcgcca atacctgccc ataagtattt atcaggtgct tcggcaataa
    30421 ttgctgtatc aatgaaggtg tgtacaggtg gttttgaagg aaagaagagt ccgtccatta
    30481 cgccttcttc gttatagatg acacataccg cagtgacggg cgaacagttc gaaccaatag
    30541 tgggaaaggt gaagactggt ttagctagtt tttcaccaat gacttttaca gtatcgcaag
    30601 cacggccacc accgactgca aacaggacgt ctgctttttg gacactttca tgctggatca
    30661 actgttcaat atttccataa gttgaattac ccccgtacca gagactggcg acaacctcta
    30721 tttcctgtgt caaagctact tttattttgt tttctgcctt tgaaagtgca gtcttccctc
    30781 caatcagcac tacttttgtc ccatattctt tgacgattcc atttgctttt tcatacgcat
    30841 ctgttccaat ggtataattt ggtaagaaaa cactttgact catatt
//
LOCUS       DACBZK010000026        30260 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.026, whole genome shotgun sequence.
ACCESSION   DACBZK010000026 DACBZK010000000
VERSION     DACBZK010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30260
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.026"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            135..1454
                     /locus_tag="IVD66_001269"
     CDS             135..1454
                     /locus_tag="IVD66_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HAP6145502.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            1895..3535
                     /locus_tag="IVD66_001270"
     CDS             1895..3535
                     /locus_tag="IVD66_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HAP6145503.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            3689..5011
                     /locus_tag="IVD66_001271"
     CDS             3689..5011
                     /locus_tag="IVD66_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HAP6145504.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(5073..5504)
                     /locus_tag="IVD66_001272"
     CDS             complement(5073..5504)
                     /locus_tag="IVD66_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6145505.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(5568..6404)
                     /locus_tag="IVD66_001273"
     CDS             complement(5568..6404)
                     /locus_tag="IVD66_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAP6145506.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(6594..6896)
                     /locus_tag="IVD66_001274"
     CDS             complement(6594..6896)
                     /locus_tag="IVD66_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HAP6145507.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(6922..7353)
                     /gene="ruvX"
                     /locus_tag="IVD66_001275"
     CDS             complement(6922..7353)
                     /gene="ruvX"
                     /locus_tag="IVD66_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HAP6145508.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(7350..7616)
                     /locus_tag="IVD66_001276"
     CDS             complement(7350..7616)
                     /locus_tag="IVD66_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HAP6145509.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(7870..8595)
                     /locus_tag="IVD66_001277"
     CDS             complement(7870..8595)
                     /locus_tag="IVD66_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HAP6145510.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(8961..9031)
                     /locus_tag="IVD66_001278"
     tRNA            complement(8961..9031)
                     /locus_tag="IVD66_001278"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8997..8999),aa:Gly,seq:ccc)
     gene            9148..9900
                     /locus_tag="IVD66_001279"
     CDS             9148..9900
                     /locus_tag="IVD66_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HAP6145511.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            9916..10395
                     /locus_tag="IVD66_001280"
     CDS             9916..10395
                     /locus_tag="IVD66_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HAP6145512.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(10646..12226)
                     /locus_tag="IVD66_001281"
     CDS             complement(10646..12226)
                     /locus_tag="IVD66_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HAP6145513.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(12219..12962)
                     /locus_tag="IVD66_001282"
     CDS             complement(12219..12962)
                     /locus_tag="IVD66_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6145514.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(13138..13914)
                     /locus_tag="IVD66_001283"
     CDS             complement(13138..13914)
                     /locus_tag="IVD66_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6145515.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(14162..14998)
                     /locus_tag="IVD66_001284"
     CDS             complement(14162..14998)
                     /locus_tag="IVD66_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HAP6145516.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(15009..15938)
                     /locus_tag="IVD66_001285"
     CDS             complement(15009..15938)
                     /locus_tag="IVD66_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAP6145517.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            16131..16484
                     /locus_tag="IVD66_001286"
     CDS             16131..16484
                     /locus_tag="IVD66_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAP6145518.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(16558..17214)
                     /locus_tag="IVD66_001287"
     CDS             complement(16558..17214)
                     /locus_tag="IVD66_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAP6145519.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            17440..19374
                     /locus_tag="IVD66_001288"
     CDS             17440..19374
                     /locus_tag="IVD66_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP6145520.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(19460..20683)
                     /locus_tag="IVD66_001289"
     CDS             complement(19460..20683)
                     /locus_tag="IVD66_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
                     /protein_id="HAP6145521.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(20677..22575)
                     /locus_tag="IVD66_001290"
     CDS             complement(20677..22575)
                     /locus_tag="IVD66_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HAP6145522.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(22569..23687)
                     /locus_tag="IVD66_001291"
     CDS             complement(22569..23687)
                     /locus_tag="IVD66_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAP6145523.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(23770..24603)
                     /locus_tag="IVD66_001292"
     CDS             complement(23770..24603)
                     /locus_tag="IVD66_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6145524.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(24596..25513)
                     /locus_tag="IVD66_001293"
     CDS             complement(24596..25513)
                     /locus_tag="IVD66_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6145525.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(25740..26864)
                     /locus_tag="IVD66_001294"
     CDS             complement(25740..26864)
                     /locus_tag="IVD66_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP6145526.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            27047..27955
                     /locus_tag="IVD66_001295"
     CDS             27047..27955
                     /locus_tag="IVD66_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6145527.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            28096..29709
                     /locus_tag="IVD66_001296"
     CDS             28096..29709
                     /locus_tag="IVD66_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP6145528.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKIKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT         9426 a         5947 c         5173 g         9714 t
ORIGIN      
        1 attaaaacca tgtgaaactg cctcacggca gcttacaatt actttttcat cttcacccgt
       61 taagtgatga aaaaagaacc cctttctgct atggttaaag tgactaaacc aaccaaaaga
      121 aaggagttct tttcatgact agcttacaca aaaaccaagt aaaattcaat tcaaatatca
      181 ctatttctca tacaggtggt caattatcga gtgattcggg tctcgtccta gtgaaagagc
      241 tgatgaacat ctttggtttt tctgaactgg ctaagcaaca cattcacatt gaagacgaac
      301 gagcgtattt tactcatgac aacttatcca tacttgagca gttcattatg caattaattg
      361 ctggttactc agctgattct gcagctaatc tcctgagaca agatcctgtg tttaaagctg
      421 ttttagatag gaaagaactc gcttctcaat cttcactttc ccgattttta gatcgactat
      481 ctgaggagaa tatccatgaa cttcaagctt tgaaccaaga acttatcgat aaagcacgcc
      541 tcatccgtaa tgatacggaa ttaatcattg atttagattc gacccattca gatacatttg
      601 gtcaccaaga acaaacgaat tataatacac actaccaaac ctatggttac catccattgg
      661 tagcttttga cggattgact ggtgacttct taaaagctga actacgttca ggaaatcaat
      721 atacatcaaa aggcgtaaag gagtttctca cacctttatt agagcactat aatcactctc
      781 taccaaacac tgacatcttg gttcgtggag acagcgggtt cgctacacct ggtgtgtatg
      841 attcgtgtga atcaaaaaag agtcattatg ttattcgact gaagaataat cgtagactag
      901 gtcaaatagc tgagaaatca gtactttatg gcgataatca aaagtgggaa gaacgagaag
      961 ttcagtactt ctcgaccact tatcaagcac aatcctggtc acaaagtcgt cgcgtgtgta
     1021 tacgctcaac acgtgaagcg ggcgaactac tctttcgaca tgaatttatc gtgacgaatc
     1081 tatcagaaaa tgtttctcct gataccatct tttctatcta tgccaaacgt ggcacaatgg
     1141 agaacttcat taaagaagcg aaagctggct tttactttga caaaacagac agtcctcgct
     1201 ttttggagaa tcatgtccga atgatgctca gcttgatagc ttacaactta gtcaacttct
     1261 taagaacgat tggctttgaa gaagtccaaa agggaatgac cattcattct attcgattga
     1321 agtttctgaa agttgctggg aaattagtcc aaacgggtag acgagtctat ctcaaattat
     1381 ctagttatca tgtgtatcag aatgaattct acagggtctt tgctcgcctg aggcgagcca
     1441 gtcaatggat ctaatccaac aatctaacga tttttttact gggaagttat ccagggagaa
     1501 gtatgctcaa aatgccttac acccaaaatt tattcctcaa tatttttgaa cagtgaatgt
     1561 ttgaagtaac tttttagtca aaatcagttg atagggatat tagtgataca tatttcaata
     1621 aaatgtgcca aagaattaaa gctatgaatt attcaggatt ctatttatct atctaacata
     1681 tcctttattc ttctactttt ctttctttag catataagag atacgcatag taatcaagca
     1741 aggattgttg atataaaaag aacaaatacc gctattttga tttcttttga ctctattact
     1801 catataaata aaatttatta tacctgctct ttttgactat atcctcatct gactcctata
     1861 cttcgtttgt attaaaactt aggaggaatc attcatgctt acagggctaa acttattaaa
     1921 taatcctttt ctaaataaag gaacagcttt tacaaaagaa gaacgggcaa aatacggaat
     1981 cactggtatg cttccaagta ctgtccaaac attggaacaa caatctgtcc aagcttacgg
     2041 tcaatactta agcaaacaga ccgatttgga aaaacgtatc ttcttaatga atctattcaa
     2101 tacgaaccgg acattgtttt ataaattgat gggcgaacat ttagttgaat tcatgcctgt
     2161 cgtttatgat cctgtcgttg cggattcaat cgaacaatac aacgaaattt tcttgaaacc
     2221 acaagatgct gtatttcttt caatcgacga accagaaaat atcaaagcaa gtttgaaaaa
     2281 cgcagcagat ggacgcgaca ttcgtttgat cgttgtgaca gatgcagaag gaatcttagg
     2341 tatgggtgac tggggtgtga acggtgttga catcgctatc ggtaaattga tggtctacac
     2401 tgccgcggct ggtatcaatc ctgcacaagt cttgcctgta tcaatcgacg ctggtactaa
     2461 taacgaagaa ttattgaata atccattata cttagggaat cgtcatgctc gtgtagaagg
     2521 cgaaacttac tacgaattca ttgatcaatt cgttcaatca gctactgaat tattcccaga
     2581 attgttatta cattgggaag attttggacg aggaaatgct gcaacgatct tagaaaaata
     2641 cgaagataaa atcactactt tcaatgatga tatccaaggc acaggaatcg ttgtactagc
     2701 tggtgtatta ggtggattga atatatcagg tgagcaattg aaagatcaaa cgatcttgac
     2761 atttggtgct ggtactgctg gtgtaggtat cgcaaacatc cttttagatg aaatgatccg
     2821 tcaaggtgta cctgaagaag aagcacgcca acatttctat caagtagata aacagggttt
     2881 attgtttgaa gatacaaaag gattgactcc tggtcaaatc ccattcgctc gtaaacgctc
     2941 agaattcact aatgctgatg aattgacaaa cttagaagca gttgtaaaag caatccatcc
     3001 aacgatcatg atcggtactt ctacccaacc tggagcattc actgaagaaa tcgtgaaaga
     3061 aatggcggct cataccccac gtccaatcat catgcctttg tctaatccaa caaaattggc
     3121 agaagcaaaa gcaaaagatt tgattgaatg gacggacgga aaagctttag ttggaacagg
     3181 tatccctgct gctgatgtgg aatataacgg tgtaacttac caaatcggtc aagcaaataa
     3241 tgcgttgatg tacccaggtt tagggcttgg tttgattgct tcaacagcta cacgagtaaa
     3301 tgctgaaatc atttctcaag ctagtcgagc attaggcgga atcgttgatg taacaaaacc
     3361 aggagcagct atcttgcctc cagtagcaaa aatcactgaa ttctctcaaa cgattgctga
     3421 aactgtcgca aaatcagttg ttgcacaaaa attgaatcgt gaagaaatca cggatatcaa
     3481 agaagctgtt gaatctgcta aatgggttcc tgaatataaa tctttagaag attaagattg
     3541 ttatagtaaa agaacataca gaaactttgt atgacgtcta aaaagaaaaa agcgactgcg
     3601 gcaaaacagc agccagccaa ctactgctct tttgccgctt ctctttggct tttttcatac
     3661 gatacagaat aagaaaggat ctgtaaaaat ggcacaaaaa acaacaaccg caactgcagt
     3721 tgaggaaaag aaaaaagaag ggttttggtc aacaaaaatt accggcgtaa gtttgcccct
     3781 ttatttgatc atggtccttg tcctgatcat tgcaatggct ttaggaaaat taccgacgaa
     3841 tatgattggc ccaatcgctg ttttggtcat tttcggtaat ttatttcatt ttatcggaac
     3901 aaaaatccct atagtcaaaa gttatttagg tggtggctcc gtttttgcga tctttgcctc
     3961 tgccgcgatt gctacatttg ggatcttacc tgagtatgta gtaaaatcca cagaaaactt
     4021 tgtcagcaat atgggctttt tagactttta tattgctgcc ttgattactg gtagcatcct
     4081 tggtatgaac cgtaatctat tgatgaaagc ttctgttcgt tttattcccg ttgcacttat
     4141 ttcaatggtc gtctcctttt ttgccgtagg actcgtaggt atgcttatcg gaaatggttt
     4201 tgcaaattcc gttttatata tctcattgcc cgcaatggct ggtggtgttg gagccggagc
     4261 tgtaccttta tcaacgattt atgcaaatgt tttaggtacg gacgcttctt ctatcatttc
     4321 ccgcctgatt cctgcgacag caatgacaaa tgtcctagct atcattggtg cagcgttagt
     4381 tgctcgtgcg ggacaatcaa tgccaaaatt caacggtaat ggtaaattaa tggaaaaagg
     4441 cgaccttggc gatggaaaac ctagaaatgt aaaaccttcc attccacaat taggtgtcgg
     4501 tttgatggta tcattgactt tcttcatctt aggacaaatc tgtaactatt ttgttcctaa
     4561 agtccatgct tacgcattca tgatcattat cgttgttatc tgtaaaatcg caaacctatt
     4621 accagaatat tacgaagatg cagctatcat gttcaacaac ttgattgtca aaaacttgac
     4681 agcagctgtt cttgccggta tcggtattgc gttattgaat ctaaatgtat tggcttctgc
     4741 tttgacatgg caatttgttg tcttatgttt gacaagtgtt atcgcgattt cagtagtttc
     4801 aggatttgtc ggtcgtttgt ttggtttata tccaatcgaa tcaactatta ctgctggctt
     4861 atgcaacaac tcgatgggtg gtacaggaaa tgtagctgtc ttatctgcag ctaatcggat
     4921 ggaacttatt gcttttgctc aaatgggcaa tcggcttggt ggtgccatcg ttttgatcat
     4981 ctcaggtttc ttgatgcaat tactttctta gtcaaaaaaa atacctgatc atcaagtatc
     5041 ggcttgatga ccaggtattt tttgataaaa atttacagga ttttcaaaaa tcttttttgc
     5101 attttatcgg aatgataacc gatgcgttca taaaatcggt gtgcttctac tctgtattct
     5161 gcagaattaa gtcttattgc tgatattcct cgtcttttcg cttcttctac gccagtcatc
     5221 aaggcctttc cgattcctct tttttcagca tgtttagaca cagcaagtgc cataatattg
     5281 aacatcggat cgctgaaaat cgattcatag gactccgctt gtacatagcc agctgctttt
     5341 ttagaagtag gatcttcata gaccaagaaa aaattttttt ctggctcctt caacagtttc
     5401 ttcatttgtc tcaccgtaac ggttaatggt acatcatatc ctaattgttc cgcattgatt
     5461 tctcgtagtg cttctgcatc tcctaaacgc atttcccgca acatccaaat caccagccaa
     5521 tttttatttt tttaaatgaa tttttttatc acagtatact ccttttttca cttaaaaaaa
     5581 gacttttcag tgattttgac ttgcttgaat ccagatcctt ctaatgtttg caagatgacg
     5641 aaagcattgt aaagattgat caaaagaacc acgatgacaa tcgcttgaaa aataaaggtc
     5701 actttttttg gagacaaaac cctgctaaat cttgctcccc acaaacctcc aataacagca
     5761 gcggggataa cataaaacaa catagataaa tcaaagcgca taaagctact tgttaaagca
     5821 atcgttacca attttgccag ttgagaaaag aaaatcgtag atagagaata tagtgttgct
     5881 tcttttattg gcaatgcaaa catcagcatc aacaaagaaa cattgactgg tccaccacca
     5941 atacctaaaa aactagctaa aaagcccaga acccccccac atataaggta ccaagtccat
     6001 gacgtcaaat gaaattttgg ctgatgatgc ttggtgtaga agaacgcaaa aaccaaggtc
     6061 aataccgtca aaaaaatttg gatcagctgc acatgcttct cgttttcaaa taactgtaaa
     6121 aaaacttcga atacaatgtt gccgactact cctccaacaa cagctccact agatacccaa
     6181 ccgacaatct gccaattcag tgatttcccg cttgatactt gtcgcacagt cgaaacaatg
     6241 gacatcgtga ataccgcaac tgttgagtaa aaagaaatcc ctgcaacaga atgggcgccg
     6301 ataagatcaa gaatcggttt gatcaacacg cctccaccca tcccggaaat agcgccaact
     6361 gtgttcgcca gaacgatcac cacaaaataa atcagaccaa tcatcttgta tttcctttct
     6421 cttgtttata tcttttagcg attgttactc ttttctttta ttatacagta aaagaaacaa
     6481 acgaggcttc gaaagctttt ctacttttta aggaaattta gtgctaaacg aaaaaaccgg
     6541 gctctacttt tcagagagtc cagcttttct tacaccttat cgattctttt gttctattct
     6601 tcttccgcca tgaatgtatt gaatacttct tcgatcatat cccattctgc gtctgtttcg
     6661 atttgttcta actcgccttc tgttccatct tcgttttcga tgtatgcata agcttgtaat
     6721 tctacatctt catcttctga aacaccagct ggatataaaa gaacatagtt acgtccaaat
     6781 tcttcttgtc cgtcaactgt tagcaagatt tcgtataatg tttcatttcc ttggtcatcc
     6841 accaatgtga tgtgttcgtg tccttcgtgt tcgtgggaat ggttatgttc tgtcataaga
     6901 ttacctcttt tctttttatt attaaaataa ttgcttacct gagccgtcta aataattttg
     6961 taaaatcatc acagctgcta atttatcgat gacttttttt cgtttcgctc ttgaagtatt
     7021 tgcctgctct actagcatac gttctgcctg aacagtggtt agtcgttcat cttgataatc
     7081 aaccggcaag gagaatagtt ctttgatctt ctctccatat gacatggaag cttctgccct
     7141 tggtccgatg gaattgttca tattcttagg taatccaact acaaaacggt ctacttcgta
     7201 ctgcgccact aattccttca accgatcaaa accaaactct tcttctgcct cattgattcg
     7261 aatgatttct actccttgag ctgtccagcc aaagggatcg ctcacagcaa cgcctactgt
     7321 cttagaaccg acatccaagc ccattactct cataaattca ctccatgatt tgagaggtag
     7381 tctttgacaa ttacttccat gatttcatcg cgttcgtgac ggcgaatcaa atttcgtgca
     7441 tcacgataac gaggaatgta ggccgggtct ccagaaagca agtagccgac aatctgattg
     7501 attggattgt agcctttttc ttccaaagcc cgataaacaa tcgctaatgt ttcgctcact
     7561 tcttttttgc gactatcgtc aaaaccaaaa cgtacggttt catctgtaaa acccatgatt
     7621 ctacacctct ttcccgcaag gtaattccag cttaccttct acacccttat tttactcgaa
     7681 gaaagggaaa actacaaaca aatattccaa acttctgaat aaattaagaa acacgatttg
     7741 tctgattttt ccttttttct gtggcttttt caaaagccct ctttccataa agtatacgct
     7801 atatttcttt gaaagtatgt ttttacacaa ttttttcata aagttcataa aaaattcgaa
     7861 ttgctgctac taatttttcg ttttcgttgc ttgccctgtc tcataattga tggtgtagcc
     7921 atcttgaaca ttgtagataa agacattgaa ttcaattttt ttgtcttcaa tgctttctgc
     7981 ttccaactgc acacctcttg ctaccagttc atttccctcg aaatgaggag tgacacgata
     8041 gcgtacatga tgatttgttt ccttgatata tgccgcaata tcattttcgt gggcaagcat
     8101 gtacggagca ttcaacgaac gtgtccctgt cattaagttt ttaatgttat tattttgacc
     8161 agtcaactgg aaaccaatca aatggctgcg gttgtataac cattgtccgt cacttaattt
     8221 cttttgtttc caacctgtcg gatcaatata caaaggttct ctcttttcag taggaaacaa
     8281 gtcttttccc aacatcgcat tggcttgtcc tactctgttc aatttgtcta tatttgaata
     8341 gctttcccat gtccctttgg aaagactaag atcctctttt gtaaactccg gctgattccc
     8401 attgatttct atttcttgat gttttccatc atattctggc acatccgcta cttgagaagc
     8461 ttgcggtgtg gaatcaaaaa tggttgtaat ttgttggaag atatctgaat ctttttgtgt
     8521 ggtggaaata ccgagtgccc ctgcaatcac agcagcgacg atccccacga tcgccttggt
     8581 tgtttttttg ctcatttctt tactccttta ctaacagttc cctaaatctt aacatatgtt
     8641 cccctataaa taaatactgg aaagaaatag aaacagtaaa aaaataaaac cagtttttag
     8701 acggcttaag aatacaaaaa aagagacgga ttcatcgtct ctactcaatc acaaaacact
     8761 atttacaagg tatttattat cattcaaaaa atttttctta atactcaaaa ctaaacggct
     8821 tctgtacgac ctcttggtaa acagtgttca aaagcttgca tctgcggtaa taagtccaac
     8881 caagtcaaaa acataagaag cttttttgct tgactattct tattacttga tgcagggcag
     8941 ctttttcaca gcctctttta agcgggtgac gggaatcgaa cccgcgacat cagcttggga
     9001 agctgggatt ttaccactaa actacacccg cgatacaaaa acagtatacg cctctttcac
     9061 tccttcctca agttttttta ttctttacgc ttccgatatg ttttgtagta aaataaaact
     9121 aatcaatcaa ttattggaga agatgctatg acgggaaaag aattagatct gttgctggac
     9181 acttgtttac tcgctgggaa aatcatgatg gaaagcaatg cggagatgta tcgggtagaa
     9241 gatacgatga gtcgaattgc tttagcttct ggaaatttcc gtttggtcag ctatgtcact
     9301 caaaccggtc tctttattgg tcttgatcgt acctcgacca tccgaatgga acaaattacc
     9361 aaccgttcga ttaatttaga aaaagtagta aaagtaaatg atctttcacg taaatatgtt
     9421 gcttcagagc taacattaga agaactttac tgcgaactgc aagcaatcga ccgagaccgt
     9481 tctttctttc ctgtctggtt gcaaatcgtt agcgcggcag tgatcagtgg aacaattatg
     9541 gtgttatttg gcggaaagat gaccgattta cctgtgactt tagtcattgg aggattggga
     9601 tacgcagctt atctatatag tttgaaattt tttagaatca aatttttatc ggaattttta
     9661 tcttctttat tgattggcat agccgctatc tacagcgtac gttttggctt aggaagcaat
     9721 caggatctaa tcattatcgg atgtgtgatg cctttagttc ctggagttca aattacgaac
     9781 gctatccgtg atttgctagc tggacattat gtctcaggag tttctcgcgg aacagaagcg
     9841 atgatgactg ctacgatgat cggttttgcg attgctttta ttttccagct tttttattag
     9901 gaaaggaaca caagtatggg gacgatattt attcagtttt cttttagttt tttagcgact
     9961 gcggcatttg ccgttattac aaatgtacct aggcgttcat tgatttgttg tggtctttct
    10021 ggtgcttttg gctggatgat ctactggatc tgtgttcaaa taggcggatc tgctgctttt
    10081 ggttcattgc ttggttcttt aggagtagca ttcatcagcg atcttttctc taaacgtttg
    10141 aaaatgcccg taacgatttt caatattccc gggatggttc ctctagtccc tggtggttta
    10201 gcttatcaag cggttcgaaa tctcgttact gaatcctatc gagaagcggc tcattatgcg
    10261 gtccaagcaa ttatgattgc tggagcaatc gctttaggtc ttgtattatc agaagtcttt
    10321 aaccataaca tccgtaattt caaagtaaag cgtgacgcaa tcatgatgaa acgaaaaaaa
    10381 cggcttttta aataaacgaa gtgtaacaaa gaaaaggttg tgaaagagac gttcagcctt
    10441 gagcgatgac aaaatatctc acaaacattg cgacaagtaa ccgcaggagc aataagaagt
    10501 aattatgagt attaaaaaaa gttttgtaaa aatagcttct cacattttta cataaaattg
    10561 acttaatact gagaaactga cttttgaaca ccctctatct gtaaaaaagg ggctgcgaca
    10621 tgatttttgt cacggcccct cttctttatt caaatttttt ccaaaacgtt cgttgataat
    10681 aaacgatcca tagagcggaa agtattagaa ctaaaccgat cacaggaata ttcactaacc
    10741 aaaatggata aaacaaagcc aacattccgt ataagacgat aagaataata ctgatgatca
    10801 atgaacccat catagttgcg actaaaccca aacttcctga acctctgtta aataattggt
    10861 taatattggt ccagttcagc agcagcaacc gataatctct agcgaaataa cgtagtgaca
    10921 ataagtagca gccgaataaa gaaccaaata gcaagctagg gataaaaaac aaaggcagct
    10981 gaaaagacag tccgcttaat aatgcgatcc caccagttaa aaaactctgc aatatccatc
    11041 cgaatctgaa cttttctttt aaatattggt tcatagagat tggcaaagaa cggataaaca
    11101 gaaaattttc ttgatccaaa gaaataagat tgctgataaa agaagtctga ttaactgtta
    11161 agaaagccaa tgcgatccct accaggaaaa caacaccgat taacttatta tctaaatcag
    11221 ttaattttat ttcgcctcct agggcaaaag caagaataaa aatgattgga gttaacaagg
    11281 aagaagaaag aacttgcata atcaaattag gttcttttac taattgagca ttgtaactaa
    11341 ataaaagctg atgcacattt tggttctttt tatgggttct ttttattttg aactcactgt
    11401 ttgaatcagt cagttgctct gtaagctttg gtactatcag ctgttttaca gcaaggaaaa
    11461 atcccagagc cgtgatagct agtattcccc aacccaataa accttgttga gaaagtggct
    11521 gactggcagc atcatagaat ggcaataata tcgaaatcgg atgccgatct gttaactcat
    11581 tttcaatagt ccccgtttga tgattcatcc acatgattcc agcaaatgcg atcagcatcg
    11641 agctgccaag caagatacta gaaactgttt ttctatgttt tttaaacact gctgttcgag
    11701 ccaaaccaaa aacaatcaaa ctagccagac aaaaaagaat aatcaaaaat agagaaaaca
    11761 aaaggattga gataatgata gtaagcaaaa tccctagatc agctcgccat ccggttaaaa
    11821 taaacatgac tagaagcgga aaaacaaaag gaatgatggt caaagcaact accaaaatct
    11881 ttgctgaaaa aacctgttct tgtccaaaag gcagaggcaa aaatacttgc aggtcatttc
    11941 cttcaaaaaa gatattataa atgactgata tactttgagt taaacctaac ataccaaaaa
    12001 gtgccacgta ataagtaaag aaacctggca atttaacaaa gttcatagca aacatagcaa
    12061 atccgtaaat cagtaaaaaa atcagccctg aaaaaagatt ttgagacaaa agatagatag
    12121 ttaatcgctt tccctttttt cctttctctc ttgctttatt cgtgagctgt ggattaacat
    12181 ataaaagatt aactcgaatt aattctaata attgtcgctt atacatacgg tccatctcct
    12241 gtcgcttgcc ttccagccat tttcaaataa atcttttcta gcgtttcatc aggtgagcca
    12301 ttcaataatt cactaactgc cccctgataa atcaattcac ctttcttcaa aatagccagt
    12361 ttatcgcata actgttgtgc ggtatccaat acatgtgtag aaaaaatgac tgtttttcct
    12421 tttgcggcat gagccttcat catttctttc aaatcaaatg ctgcttgagg atcaagtcct
    12481 tgcaaaggtt catccaatac ccaaatatct ggatctggca gcaacgtgcc gatcaaaatc
    12541 gttttttgac gcattccatg tgaaaaactt gcgattgttt cattttgatg actatacata
    12601 tcaaaaagcg ctgtcaattc tgctaaacgc ttttcttttt tttgtgtgtc taattcatag
    12661 gcagctgaaa tcaagtccca atattctcca gccgtcaatt gtaaaaaaat atctggggaa
    12721 tcaggcacat aaccgatttt ttgtttgata ctcaatcgat tttccgtcaa tttcattcca
    12781 tctactaaaa tcgttcccga tgatggttca ataatactaa ctaaactttt aatcgtagtt
    12841 gattttccgg caccattatg tcctaaaaat ccaaaaattt ccccttgtct tatcgagaga
    12901 gacaagtctt ttaatgcttg ttttttcccg taacttttac ttacattgat gaattcaatc
    12961 atttctgtac tccttttgtt tgttattact ttttattgta cccttcgtta ttggtggagt
    13021 aaatgtcaaa aagagtgcat aacaaaaaag gatagaaacg actaggctgc tacttgggtt
    13081 gttctcttct acaggaaaac actcttctaa caggtaagat atgagtcttt gttttcttta
    13141 aaatgattca ttttctatct tttcttgcat aaaattcttt agtttatcaa tacttctctt
    13201 tcccatctct agttgttctc catttgcaaa tgttactatt tcgtttactc tgctaataga
    13261 tgtaatgttt tcagtattaa tgatataagc ttttaaatct ttacataaat actcatattc
    13321 gagtgatttt ttatattttt taattgtgcc gtttacgaga atctcttcat ctttcaatac
    13381 taggcctatt ttatttttat aacctggcat gctcattaga taaaggattt catcgtaatg
    13441 gatatagtga tcgctattac cataacggac agttgtccac ctttttttcg tagcatgttg
    13501 aacaggatag ttttcttttt ctttcaataa gtaactttgg atgctttttt tatttttttc
    13561 ataagtgaat tcttttatca aataaccact aggcgtaatc tttcgattaa taacagttat
    13621 tgctttattc ggatgagacg ttagataaac aattttacac ttttcattct tttctctaag
    13681 catttcgcct agttcgatac cgctataata ggcgttcaaa tcgatgtcta ggaaaaaaat
    13741 atctgaggaa tagatttcat tatttttaat gaattcaaca aattgtataa cgttcaatcc
    13801 ctgaacgatc tcaaatttcc aaggacttaa taaaattctg gattcttcca aaatttctac
    13861 tagcattttt tcaaaaacca aactatcatc caaaataaat atacgcgtta ccataaaaag
    13921 tacctccact cgatatttta ctatcaaaat catttcatac aacttttcaa catacatgtt
    13981 aggaataaat tgtaattctc ttcacaatct tttccaacac ctttgaaacc gatatcaaat
    14041 actttcagga tgctgcttct aaaataaata tcaaacaaat gaatacatca tgcaaaaaaa
    14101 gccagacaac cgacgtcctt gcgtgtcagc tgtctgagct atgtttattt attttgttct
    14161 tttaaaaaga acgatacaca tactgatttt tcggagcaga gactttctca gcgtttgtaa
    14221 caactacaga tgggatttca cgcttgaatg gttgataata gtctgattgg atggttcctt
    14281 ctattttata ccattcatca tttttaaccg ttactccttc cggcatatgc gtcaacaaac
    14341 caaagactcc tgaatctgcc acacaatgga taatgccgaa tcggaacaag aagatatctg
    14401 tattgctatc gttcggtgtt tggtaaacaa atccttcata gctgattttt ttgccaatga
    14461 attcgctagg gtaattataa attagctcca taacttctaa atagttttca tctgtgatct
    14521 tgatagtttg cttatcccca tacttttctt tcaactcatt catttggtct aagtagtctg
    14581 atttgttgaa ataaatactg gtatccggct ttaagtattg tgtctgcatc tccggatccc
    14641 ctactgattc tttacttact gggaaattaa atcctttggc ttctacgatc gtagtgtcga
    14701 gactaactgt tggaaacaac gtccccacga ttactggcaa agctagcagt acataagcga
    14761 ttccacgttg ataaggtttt gacaacccat ggtcatgatc gtgctcgtgt gccttttctt
    14821 ctgcttttcc gtttttgacc cacaaataca gctgaactaa agccaaaaga gcagataaaa
    14881 tcattgaaag aatagctaag tagcgataat ggacattgat atattgatcg agtttgccag
    14941 aaacttgcaa gtacatcatc aattcgaaat acccagataa aatcaaaaac cgcagcatat
    15001 tttccctcct aaataaataa tgtgaatcca ataacgctaa gggcaatcag tccgatcagc
    15061 gataaaataa agcgtcctgt aaaatatcgt ttcatcatca gtagattttt gatatcgacc
    15121 attgggccaa agaccaaaaa ggcagctaca ggtgctgtgc cgaacagact taacaaagaa
    15181 gatcctataa acgcatctgc ttctgagcaa agagacatcg taaaggccaa taacagcatg
    15241 atgataatgg ctaaaatctt tgttgagccg agcgttagca taattctagt tggtaaataa
    15301 gtctgcatcg cagctgcgat taatccgcca atgatcaaat aacgacctgt atcaaaaaat
    15361 tcgtcgattg aatgtgtcaa cacatgccca gtttgatgga tcagctgatt ttttggttca
    15421 ttcttctcac tttgttcttc ttcatggaca tgatgatggt gattttctgc tactttagac
    15481 gtgatttttt ctttcaatac agcgtctttt tgaaaatagg caagccagac accaatcaca
    15541 agggcaacaa aaaagctgcc tatcacccgc cagcttgcca tctgccaaga attgccaaat
    15601 gcgataaaag tggaaaaaat cacgattgga ttgatgatcg gagcagtcag cataaaagca
    15661 aacgctgtgt gaactggtac gcctttttta acaaattgat gaacgatcgg tacgatgccg
    15721 cattcacatg aaggaaagaa aaatcctaag atcgaaccag taaaaataga gaagatacga
    15781 ttttcaggaa gccatctctt cacacgttct ggggtcaaaa atacttgtaa ggcgcctgag
    15841 ataagacagc ctaataatac gaaaggtaat gcttcaataa cgatcgataa gaaaatcgta
    15901 ctcatctgca aaaccgaatt tggaataaaa gaaaacatga gtttcctcct ttttatttct
    15961 agttcattcg ctttgcaaat atacgctttt attcaaaaaa aaacaagttg ctctgtaaat
    16021 ttttacacaa ctcttatttt ttaccaaagc acttcaattg actttttctg ttattcccat
    16081 taaattaagg tctcatacat atcacttcta tcataaaagg gagaataaaa atgaaacaaa
    16141 ccactaactt gactgaagtt caagacatac tgcaacagtc atccgttgcc gtcatttatc
    16201 tttcgatgcc taattgcagt gtttgtcacg ctgttcgtcc acgactagag gaacttctca
    16261 cacattatga tattccggca cttcatttgg atgcatttga aacaccagaa gtagctagta
    16321 aatttgaagt gctgactgcg ccagttgtcc tgatttttca tcaaggaaaa gaagtctttc
    16381 ggcaagcacg gttcatcgac tttaaaaaaa tccgttatct actagatgaa ctgacagcag
    16441 aagatgattc cctttcttat gaagaaatct tccgaacaaa ataatcgttg tccaaacaga
    16501 aaaaagcgat tgaacaagtg aaagttttgc cttcatttgt tcaatcgctt tttattttta
    16561 ttctgctgta ttttcggaat gcgcatttgc gtcagaatgc aagaaataga tcaaggtttg
    16621 caattcattc gtcaaatcaa cattttggat caatacatct gacggagcat tcaatcgagc
    16681 agcggtaaag ttcaagattc ctttgattcc tgcttccgtt aactgattga ctacttcttg
    16741 tgctctttca gcgggtatcg ttaaaattgc tacttcgatt tgttggatct tgatttgttc
    16801 tgacatatct tccattggat aaacggggat accgtctacg atgcgcccaa cgatttcctc
    16861 attcacatca aaagcacaac tgatacgtat gctattactt tgatggaatt tgtattttag
    16921 taaagcactt cccaagttcc ctacaccgat cagcgcaaca tttgtcaatt gatcgtcgtt
    16981 taatgtcttt gcaaaaaagt gcataagatc ttctacatca taaccatacc cacgttttcc
    17041 taattcgcca aaataagaaa aatctcgacg gatcgttgca ctatctactt gaacggcttc
    17101 acttaattca gttgaagaca cttttttctt tccagcatta tttaaaatcc ttaaatagcg
    17161 ataatacaaa ggcagtcttt tagctgtcgc ctttggaata atatgatctt tcacgaaatg
    17221 acctccacgt attgtctaat tacatctttg atttctccat catagcagta tttataggaa
    17281 aaaatcaatt ccattgctca gatattgtga aattttattc tttattcatt tatttatcat
    17341 ttctgcaaat ctcgcagtat aatggaattt atggtagact actaattgaa aaatagtttt
    17401 ttatttgagg agaattcaca aagtagaaaa gaggattcca tgatattatt acaagccaat
    17461 cagattgctc gccattttgg tgcagaagtc ttatttgaaa acatacattt agaaatcagt
    17521 acaggcgctc gtgtcgcttt agttggcaga aatggcgctg gaaaatcgac tttattaaag
    17581 atcattgctg gaattgaagc acctgatgaa ggaaagatcg ctaaaaataa aacagcgact
    17641 ctcggatacc tcgctcagga cacaggactt gattccaatg aaacagtttg gaacgagatg
    17701 ctgaaagctt ttgaacaagt tagacaaatg gaagagcgga tgcgcgagct agagattttc
    17761 attagcgaag gtacgccaga cacacctgct tatagttctt atttaaaaga atacgaccgg
    17821 ctgcaacacg atttttcaga tcgaaacggc tatggttatg aaaatgaaat tcgttccgta
    17881 ttgcatgggt ttaaattcga ttcttcattt tatgatcaga aaatcgatac tttatcaggc
    17941 ggacagcgca cacgtttagc tttagctcgc atgcttttgc aacaccctga cattttgatt
    18001 ctagacgaac caacgaacca tttagatatc gagacacttt cctggcttga gaattatctg
    18061 caaagctata ctggtgcatt attgattgtt tcccatgacc gttatttttt agataaagta
    18121 gtcaatgaag tctatgaatt aagcagaaga aaaatgcgcc attacaaagg taactattcg
    18181 aaatatctag atttgaaagc agaacagtta gcaagtgaat ggaaggctta tgaaaagcag
    18241 caaacagaaa tccataaatt agaagacttc gttgctcgga accttgttcg cgcctctacc
    18301 acaaaacgag cgcaaagccg cagaaagaca ttagaaaaaa tggaccggct ggatcgtcct
    18361 caaggggatg aaaaacaagc aaactttcta ttcagtatag aaaagccttc tggaaatgta
    18421 gtcttgcaaa tcgaagatgc cgctatcgga tatgataatg tcaccttatc tgaaccaatc
    18481 aatctagata tccgtcgtca agaagcgatt gctctagtag gtccgaatgg tatcgggaaa
    18541 tcgacgttgc tgaaatcaat cattcaccag atccctttta tccgtggaaa agaaacgcta
    18601 gggacaaatg tcaccatcgg ctattacgat caaggtcaag ctgatctgca tacaaacaag
    18661 acgatcctag cagaattgtg ggatgagcat cctaccactc cagaaaaaga gatccgaagt
    18721 gctttaggtg ctttcttatt ttctggcgaa gatgtagaaa aaccaatccc tctgctaagt
    18781 ggcggtgaaa aagcacgggt tgctttagcc aagttagcga tgaacaaaga aaattttttg
    18841 attttggatg aaccaacaaa ccatttagat attgacaaca aagaagtatt agaaaatgca
    18901 ttgatcgatt atgacggcac actgcttttt gtttcccatg accgatattt catcaatcgg
    18961 atcgcgacaa aagtcgtcga actctctgaa aatggcagca aagtctatct aggagactat
    19021 gattattatt tagagaaaaa gcaggaagaa gaagaaatcg ccgaattgtt ggcacaagat
    19081 gagccagaat ctgctcctgc tcccacgaac aaatctgatt attaccaaag caaagaacag
    19141 caaaagctta tccgtagcct tcaacgaaaa attactcagg ttgaagaaga aatggcgcgg
    19201 atcgatgaat ggatcgatca gttggaacaa gaaatggtcg cgccagaaaa cctggaagat
    19261 cacgtaaaac tcaatgagct gaaccaagat ttagaagctg ctagacaaga tcaagaaaca
    19321 aaattgacgg aatgggaaga actaagcttg gaattagaag aatatgaaaa ttaacgaaaa
    19381 aaccaaaaca gaaaccattc atgctgtttt ggtttttctt tttttatttt atcaaacaaa
    19441 aattccatat ttaccttttt caccaataag aagaccaatt actagtcatt ctcactaaag
    19501 cttctaaata atagtaatca ccccaaatac aaggtgtatt taccccatta tttttgggct
    19561 tattataaac agactgtgtt aaaaagccat cttcttcttc cgttgtagca tatctttctt
    19621 tcaattgtcg cataattttc caaacagcag actggtataa gttcttttct gttttgtcta
    19681 atagacctga ttctattaat tctaataatc cacaaaccat gatcaccata ctagatgtat
    19741 ctttttcttc tctgctagaa tcatcaaaga tcaaatccca ataacaaatg gtatcttctg
    19801 gcaaccgatt cataaaataa ttggctaata ttttgcttaa atcaaaatat ttttgttctt
    19861 tcaaataacg ataacttaat gcaaaaccgt aaatccccca tgcttggcct ctagcccaac
    19921 aggaattatc actataacct tgatgcgtac ttccatatct tggttttcca tctttgacat
    19981 ccatataaaa tgtatgataa gttgaaccat cttctcttac taaataatct gctgcatttt
    20041 gaatatgagc ctgagcagct tttttatatt tttgatttcc agtttcttca ctcgcccaat
    20101 acaataatgg aagattcatg caacaatcca tgatcattct accttgttgt gaaggatcac
    20161 taggatctcc ccaagcttgt ataactcctg ccttctccca aaaacgctga agtaatgttt
    20221 ctgcagcatc aattgaagct tccttcattt ttcgatttcc cgttatttta taatctgcta
    20281 cggttgataa agaatacaaa aaaccaagat cgtgatgatt agtgataatt tgacagtcaa
    20341 tcctgtggat aaaatctata tctgcttttt cagctgtttg ttgaaataaa ggatcacccg
    20401 tcttctcaaa taacaaccaa ttaattcctg tccaaaatcc ttctgtccaa ccaatattgt
    20461 ctcttaatgg ataacgtcct tttataggac actcgcttgg gaattgatac tgactgttac
    20521 tgatacgttt gattaacctc tccgtgtgtc tgcgacaacg ctcgatctca ttattccatt
    20581 ctttttccat taattcttta taacattcat ttatccattt ttctggatgt attatctctt
    20641 caaacatcac tttatcaagc atttccccac cagcctttag cataatttta gtcttttttt
    20701 attgttttta ttttggatag ttagcccggt tgtcccatca aaatcaattt tgggacgatt
    20761 gttccatact tctaaactat aatcccgatc ttgatgagca accactcctg ttccgagcca
    20821 atgggttcct tttccaaatg taccctctaa tccaggaata aaagtgtttt cccatgtcat
    20881 caagtttgta ttgggcaaac ccataatagc tgtggatttt cgtttaatag tatcgtcact
    20941 taaacagata atacctgaaa agccagcttc actcacccta tagttttcct tgtcttcttc
    21001 tatgattatt ccttctttct caggagaaca ttcaatagca aaccctgtct catatagaac
    21061 atattctgta tctaattcta ctttgtgtac gcgaatctgc cagccttcaa aaggaataag
    21121 ccaagttctg atttttgcct gtaaagtagg ttcccatgta gaggcaagta cctctttctt
    21181 acatacaatg tctcgtacat tatttcgaac gatgaactgt ccataggttt tgatgctctc
    21241 attcttaaaa ctggtcgtga tatatgtgtc cgctcgctga atccctagca ttgaatccat
    21301 tgccatttct gctttcaatt gattcgctcg cggtatcgaa aaaccaaatt gactagaata
    21361 agcaaatttt aaatattttt cattggtcaa tgtatggaaa tttggcccta attgtcccgc
    21421 attcaaaaaa aatgtatgtc cattatcatg ttgtatgagc aaattggctt ctgaaagaag
    21481 tttagttcct tcacgaatag gcataggcat ttctttagcc gtccaatact catggtcttc
    21541 aggtagcgcc aacaataaaa aaatcttatt cagccataat ggagataacg tactattata
    21601 gggttcagtc aatgtcaatt gagggtaggt ataaccaata ttcaggatac ctttttcatc
    21661 aaatatttct ttttgcatcc accatcttat attccgattg actaacccct tgatttcacc
    21721 taatttaaaa ggcaaaagat cggcccacaa catagctgac caaaagcttg aaactgcaaa
    21781 acgataaatc atgcttcgac caaaaggcac atttgcacca tcttccgcaa aaaaatgaat
    21841 atagtctcta gaaaaatcaa tagctcggtt cttatatatc tggctaatgg gcttttctgg
    21901 ttctagtacg ctataaatca aaccataata atgaaatgca aaaggattat aataatcttg
    21961 gcgacctctt gaactgtctc gataccagcc attttgaaga taacaatttt ctatattatc
    22021 aaatgcttct ttcagtgctg attctttaac tggataacca aatttttgga taattgttcc
    22081 gacaattatc ttaaaaaatt gccaattacc atctgcacat tcatattcaa aaatttgcga
    22141 gaaccaatga ataatctggc ttttttctcc tgtatctaat tttttccata ataattgttc
    22201 atgatgatat aacgctaata acattgcggg catttctacc atacgctggt ctctttcatg
    22261 tatttctccc caataatcgg gatgggaagg atctgttcca gcttttattc ctgatagaat
    22321 taatttcaac catcgttcat ctaattggtc aattgcgggc cccgctcccc ataaaacccg
    22381 agagaatcct tccattcctg caattttatt tccatatcct accccttgat gtatataatc
    22441 aatttgtgcg ccacttgctc gataaaacgg ctggagtggt tgatttatct ttttaaataa
    22501 gtcaaagtaa tcctgtctgg tccttaatag tggtactgga tgtttcattg tattttctcc
    22561 tctttttact accaaatagc taattccgac tgttctaatc gaagtaagcc ttcaataaaa
    22621 aaataatcag aatagatcag tggcacatta taagtcagtt ctctatggta tgcttctgct
    22681 ccgcctccaa tgatcccatc ttcatccata ttccaatttg catagtgctt ttctgtcttt
    22741 tggagtatat tgatagcagc ttcatgatac atttttgatc gtacagagga aacatatcct
    22801 gctaattcca gaagaccgca tgcagcgcat actccagcac tggtatcaat attcgaatct
    22861 tttacagcaa aatcaatgag aggaatataa ccagtttttt cgattttctg aataaaattt
    22921 actgctatct tttctgctat agctagatag tacggatttt ttgtgtaacg ataacttaac
    22981 gcgaatccat ataaagccca tgcatttcct ctgctccaac aagaattctc attgtatcct
    23041 tgcccgccaa gtaaccgaat atatttccct gattctgcat caaattctgc gatatgcccg
    23101 gttgatccat ctttcctcac tagatactta gctgttgtat ctgcatgctg ccgagcaatt
    23161 ttagagaacc tcggatcacc agtttccctc gaagcccaat acagtaatgg taaattcatc
    23221 atactatcaa taatcatcca accaggttta tggtcattcc atgctactaa atagttccct
    23281 gaaatattat agcgtccagc aagtaccgta gctgcatgta accctagttg tcgactatgt
    23341 ttgttttgag actgttgata atgtgcaata gccgatggta agaataaaaa acctacatca
    23401 tgatgaacgt ctgaaaaatg gtacagggca gattctaata attgttcttg ttgtattgct
    23461 gcctctttga acttttctcg ttttgtcttg tgaaagagct gccataaaat accactccaa
    23521 aaaccattgg tccaccagtc gattcctctg tcctttatta cgtctgtata ttttccgttg
    23581 taagaaatat atggaatttt attccccatt ctgtctaatt ccgcatctat cttttcagaa
    23641 gctacattca aaatttttct tgaccattcc ttcgtctgtt cattcatgga tatcccgcca
    23701 ttcttttaat ttttatgaat gtggagttgc tcctagaacg aactagatgg ttaacattcg
    23761 ttattttttt tacttatttg cagctccaat gtcattctcc ttaaatttag actgcgccca
    23821 cacataaatc aagaccattg ggatcactga agttgctaaa attagcataa ttgcgccata
    23881 attaattggc tcacctgtac tagaaaccgt catatttttg ataattaagg gaaccgtata
    23941 tttatcttta tctgaaagca tgactaatgg aaatagatat tgattccaac ttcccataaa
    24001 gataagtaaa ccactagtaa taatcgtagg tgataaaatc ggtacagcga ttttcgtaaa
    24061 aatcacccac tcattggcac catcgattct ggcagcctcc atcagtgctg taggaaattg
    24121 actgctatat tgtcgcatca taaacactga agttgtactg gcaatcgaag ggatgatcac
    24181 acctgcataa gtattcgata atcctaaacg actcataatg taaaataaag gaatcaatgt
    24241 ggtaaaaaaa ggcaccatcc tagatagcat aactgtattg aacaacagtt tattccccat
    24301 aaaacgatac tttgctaatg cataacccgc cattgtagaa ctggctgtag ctgaaactgt
    24361 actgattaca gcaataacaa tcgaattcca aataatcaag ggataattat atctcgccat
    24421 gatggcttgc cagtttttta atagcatatc cccaaacttg aaattgattc cgccacttaa
    24481 aatttcttga ttactttgcg ttgaagctac aatcatatat aaatatggca tcaaaaatat
    24541 taaggcacca aacacaataa tgacgtacgt aaaaattctg ctttgtatct tttgtttagt
    24601 catttttatc acctccgaat ttaaattgaa tagccgataa tataacagat acaaacacca
    24661 tcgtccaggc aatagcagag gcttttccaa aatcaaccat ttcaaaactt gttttatata
    24721 aattgactcc tacgaccaaa gctgaatttt ctggtccatt ggaagtccca aagaatatat
    24781 ttgggatatt gaaattaccc aagccattga tagtggctaa aactgtggcc attaaaatga
    24841 ttggctttag catggggatc gttaataaaa agaattgccg aaatttcgat gctccatcta
    24901 tttcagcact ttcgtatatc tctttagaaa tcccttgaag accagctaaa aataaaatag
    24961 tgttatatcc tacactaagc caaatcatcg tgatgatcat tgatattcgt atccaaaaag
    25021 gatttgttaa ccactgtaca ccgttaattc ctagcgcatt caaaaatcca ttgaataacc
    25081 cagtcggatt gaaaaaagtc atgaatacgg aagctacagc caccgttgat gtaatggttg
    25141 gaatataata gacagttcta aaaaatcctt ttccttttaa ctgtgctgaa ttcaataaaa
    25201 cagcaaagta aatagctaat agcatcgtta ttggaattga tcctgccatg ataatcaaaa
    25261 cattcgtgta agatttaata aacaatggat ctcggaagat agctagataa ttgtcaaatc
    25321 caacaaattc aaatgagtag ccaattttca taaaactaaa agcaaacgag ataatgatgg
    25381 gaatcaaaat cgtcacaata aagaaaataa caaaaggtgt gaccaatcca taagcacttt
    25441 ttttatgaga cgtatctgtt gcttttttct tgctgttctt tattgtcttg cttggtaacg
    25501 aagattgcat catcgttaag tcctcctaat attttttaat caccagttaa ttttacgccg
    25561 tacttatgag caaaattttc tgcttctttt agatatgaat tttcaaaatc acctgtttgc
    25621 caatagttat atgcagcggt agtcaaataa gacgtagcat ctgaataagt ggctggtaaa
    25681 acagtatttg atgtattttc attgatttta ttcaatagtt catagtattt ttgtcctcct
    25741 tagtagtcaa actttttctc agctgcttct gtttgatagg ccaatgagtt agatgtagcc
    25801 acgcccagct ccagtgcgtt ggctaagcat tcttcatctg tcagcataaa tgtaagaaat
    25861 tgttgtgcca cttgtggatt tttggcatct ttagggacat aaaaacttga tcctcctgat
    25921 actgcacctt ttcctggatt ttcttttgaa aaaggaatca gtggagccat gcgccatttg
    25981 tcagatgcat caggaaaatt caaagacata ttcgtagcat accagccgcc agcaacaaac
    26041 attgcagatt cttgaaatgc tttctcagca tcttgtgcac cgtagaaatg tacaatatct
    26101 gagtcgatca tttctttgat taactttgca gcatgtttcg cttctttagt attcagacgg
    26161 atatttcctt cttcatcaag caaagattga ttctgctggg ctagcatgtt gataaacaat
    26221 tcttggtccc cagattctgg caaggcaatt ccaaaactac cagttttttc ttttaatgct
    26281 tttgccacct ggatatattc ttcccaagaa ctgatttctt caaaatctac acctatttca
    26341 gcaaattttt ttggttgata ataacaaagt gctggggtaa aatcactagc ccaaggaata
    26401 atcgtttcat tactcgtttg ttgacgcaaa atattcaatt tttgatcata aaactgatcg
    26461 ccatatttgt cataaaatcc atattcatca gcactataaa aagcatcttg aaatttttcc
    26521 agcacacctg ctgctgaagt gtctgccatg gagataatat ccggcatatc ttcgtgtgtt
    26581 accaattttg gggtgatcat ttgtactgtt gctgttcccg aagctacatt cacaattttt
    26641 aagtcaatat ttgctccagt tttgcggtta tagatttttg cagcattttc aacatagttt
    26701 gtcagtttgc cgtttgcgac atatacttct aatgtagtgg ctttttttat cattggatct
    26761 gcgatgtttg ctgttacttc ttcgttagtt tttccacatg cacttaagct gaataatagg
    26821 gtaatgttta gcaaagctat caccaatttg tatctttttt tcatgtctat cccttctttc
    26881 ttttcaagtt cttatataaa acgctttcac ttatgtatat taacggaatt agtaacacaa
    26941 atatttatat aaaaaaatat tttacttgtc gttttggctt ttcatttttg ttataatagt
    27001 cattaattat aaatagaaag ctttttatat aaaaagagaa aggaaagtgg ttcttttgtt
    27061 aacaaacaac caatcctcca atcttgtcaa aaaaacacta acctattcca tagataccca
    27121 tcttcattta tctgctgctc cctattttcg actactaata aatgaaagcg ctaatttata
    27181 tgctgaattt gcacataaat ctatagaact agataatcct tcccttttat tcattgataa
    27241 acagcaagaa gtccaaatct tttctactca aaaggaaaca caaactttta tcattatcca
    27301 gttttatttt gatgagcaat tattagcaca tattacggga caatcttttt ctatagatca
    27361 agaaataaca tctatcatta cttttctgaa aaatgaacag ttcaaaattg attatctaaa
    27421 acatagtaag ccagctattt cctatgatca ggaaatcaat tcttttttca tactatgcca
    27481 acagatgagc attcatttgc tttccttatt agttacttat tgtctgcaaa aaattcaatt
    27541 gtcttcctta ccaaggcatt atcaacagga acttgcttta ttgacaatac cttcaaatga
    27601 gaaagtcatt cctaaaaaaa agcatattct ttattcagat gaattagttg atccaatcat
    27661 acgatattta gaagaacatc tttcagaaaa ttttttgctt gaacaattag cccaaatttt
    27721 ttttatcagt ccagccagct taaaaaaaca ttttagaaaa gtgaatggaa aaagtgttat
    27781 tagctatttt aaagaactaa aaatggaaaa agcaaaacgt ctcgtgctag aaaatgaatt
    27841 aacctataca gaaattgcag atatattagg atttcattcg atccatcatt tttcttcagc
    27901 ttttaaaaaa tatacagggt tatccccttc aaagtattat ctatccttaa aatagaaaaa
    27961 aatttttagg ttttatccac aaattatttc tctatatttt ctgtctattc aaaataaaca
    28021 ataattttcc ggcacaatta tttgctgttt tttaccataa catagtacga tcaacgtaga
    28081 aaaggagatg tttttatgaa agttgttgtc attggcggtg tagctggcgg tccttcattt
    28141 gccactcgtt tccgtcgatt gaatgaagcg cacgaaatca ttatctatga acgcggagaa
    28201 aatatttctt atgcaagttg tgctttgcct tattatttag gaggtgtgat cactgaccgt
    28261 gactcgctga tcgaacgtac accagaaata ttgaaaataa aaaacaacat cgatgtcttt
    28321 actaaacacg aagtaacagc aatcgatcct tctactaagc gattaacagt taaagaccta
    28381 tccacaaatg aagaaataaa aacagattac gataagttga tcatctcttc tggtgctaga
    28441 ccagattatc cggatattcc cggagttttt gaagcagaaa acggctttgt cctccgtagt
    28501 gtgacggatg cggatcgaat caaatcgttc cttgaagaaa aaaatccaca acatgtcgtc
    28561 attcttggtg caggtgttat gggtctggaa ttagctgaga atttcaagca tcgcggctta
    28621 gacgtgactt taatcgatca attgccacaa gtcgctttcc cttatgatcc agaaattgct
    28681 aatttagttt atgacaaatt gctgaaagaa ggattagccg ttcatttaga aacaagagtt
    28741 actgagatcc gtgataaagg tcgagaaata gtattatcag atggctccgt cctttctgct
    28801 gatatgctaa tttttgctgt tggtgtttct ccgaagaatg aagtggtgaa agcaaccggc
    28861 atacaattat cagatacagg tcagatcatt gttgatgacc agttacaaac caatctgccg
    28921 gacatctatg cgattggcga tattatcgaa acgactagtg tagtgactgg tcagccgatc
    28981 caaagtatgc tttccagtgc ggccaatcgt caaggacata tgctggcaga tattttaaat
    29041 ggtacgccta tgcgctatcg cggatatatt ggtgcaggtg tcgcaaaaat ctttgatcat
    29101 acagcaagtt atgcgggaat gacagaacat gaattaaaag catcaggcat aacaaattat
    29161 aaaactgttt ttatcactcc ctttgaccat gcctatttct atccagaagc tacaagatta
    29221 aatctaaagc tgatttttga tgcagatagc ggtcgtattt taggtggaca agcatttgga
    29281 gaaaaaggtg tcgataaacg gatgggagaa ctttctgtag caatcaccgg aaacttgaca
    29341 gtctttgatt tgcctgattt ggagttgcct tactctccac cgtattctac tacccgtgac
    29401 ccgttgaata tagctggtta tgtcgcaatc aatcaaatga cgaatatcgt agaaacgatc
    29461 aaagcaagtg atatacccga aaacgatttg aaagaagcgt tctttttaga tatacgtgaa
    29521 cctaataaag caccttctgg cagtatctcg gcaacaaaaa atattccaat gaatgagtta
    29581 cgagatcgaa tcaatgaaat cccaaaagat aaaaaagttt acattacttt cagaagagga
    29641 ttgaatactt atacttctgc ccgaatcttg gcaggtttgg gtatcaaagc gattttgatt
    29701 gaagaataaa aaaacgaccg cggtgggtag ccgcggtcta ggagttattt ttacttgagg
    29761 agtaaaaatg aaaaagtata tagggttgtt ggttggtatg tatatagaat agaagataaa
    29821 tgtgaagaaa ttgtgcatta tttcttcaca tttattaggt tatagtttaa gaaagtttaa
    29881 acattgcgca atttaattat tttagctgtt tcttttcata aaaaaacatg ttgtgactct
    29941 gagacaaatc atagtccata gtgatgtctc tagagtaact acgcctaata ttacgaggca
    30001 tcatattaat ctatcagcac tagtacctaa actagcatcc ctttcgaata ttttttctta
    30061 tataataaag tttgctttca ctcctctaat ctcaccaaat cgactggctt gcgttgtgtg
    30121 atactaggaa ctgattggtt tagaacgact tttctattgt aatcatattt ttcgccatcc
    30181 tcgttgtctt ctaatccttc aatgaatgat ccctaatgtg tgtattaaat aatttaattt
    30241 ttttgttcct atttatttaa
//
LOCUS       DACBZK010000027        29154 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.027, whole genome shotgun sequence.
ACCESSION   DACBZK010000027 DACBZK010000000
VERSION     DACBZK010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.027"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..1030)
                     /locus_tag="IVD66_001297"
     CDS             complement(<1..1030)
                     /locus_tag="IVD66_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6145529.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="IVD66_001298"
     CDS             complement(1112..1801)
                     /locus_tag="IVD66_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP6145530.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="IVD66_001299"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="IVD66_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HAP6145531.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="IVD66_001300"
     CDS             complement(2328..2831)
                     /locus_tag="IVD66_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HAP6145532.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="IVD66_001301"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="IVD66_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HAP6145533.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="IVD66_001302"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="IVD66_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HAP6145534.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="IVD66_001303"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="IVD66_001303"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit beta"
                     /protein_id="HAP6145535.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="IVD66_001304"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="IVD66_001304"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HAP6145536.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="IVD66_001305"
     CDS             complement(6443..7462)
                     /locus_tag="IVD66_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAP6145537.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8522)
                     /locus_tag="IVD66_001306"
     CDS             complement(7635..8522)
                     /locus_tag="IVD66_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP6145538.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="IVD66_001307"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="IVD66_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HAP6145539.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="IVD66_001308"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="IVD66_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HAP6145540.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="IVD66_001309"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="IVD66_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAP6145541.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="IVD66_001310"
     CDS             9753..10397
                     /locus_tag="IVD66_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP6145542.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="IVD66_001311"
     CDS             complement(10453..10956)
                     /locus_tag="IVD66_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAP6145543.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="IVD66_001312"
     CDS             11553..12518
                     /locus_tag="IVD66_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAP6145544.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="IVD66_001313"
     CDS             complement(12617..13789)
                     /locus_tag="IVD66_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6145545.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="IVD66_001314"
     CDS             complement(13776..14921)
                     /locus_tag="IVD66_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6145546.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="IVD66_001315"
     CDS             complement(14935..15867)
                     /locus_tag="IVD66_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6145547.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="IVD66_001316"
     CDS             15984..17063
                     /locus_tag="IVD66_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP6145548.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17689
                     /locus_tag="IVD66_001317"
     CDS             17060..17689
                     /locus_tag="IVD66_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6145549.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17799..18026)
                     /locus_tag="IVD66_001318"
     CDS             complement(17799..18026)
                     /locus_tag="IVD66_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP6145550.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18129..20717)
                     /locus_tag="IVD66_001319"
     CDS             complement(18129..20717)
                     /locus_tag="IVD66_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HAP6145551.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20737..21396)
                     /locus_tag="IVD66_001320"
     CDS             complement(20737..21396)
                     /locus_tag="IVD66_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP6145552.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="IVD66_001321"
     CDS             complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="IVD66_001321"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HAP6145553.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22169..23035)
                     /locus_tag="IVD66_001322"
     CDS             complement(22169..23035)
                     /locus_tag="IVD66_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP6145554.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23144..23785
                     /locus_tag="IVD66_001323"
     CDS             23144..23785
                     /locus_tag="IVD66_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HAP6145555.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="IVD66_001324"
     CDS             complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="IVD66_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HAP6145556.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25226..26125)
                     /locus_tag="IVD66_001325"
     CDS             complement(25226..26125)
                     /locus_tag="IVD66_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAP6145557.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26127..26924)
                     /locus_tag="IVD66_001326"
     CDS             complement(26127..26924)
                     /locus_tag="IVD66_001326"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HAP6145558.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26902..27606)
                     /locus_tag="IVD66_001327"
     CDS             complement(26902..27606)
                     /locus_tag="IVD66_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HAP6145559.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27737..28312
                     /locus_tag="IVD66_001328"
     CDS             27737..28312
                     /locus_tag="IVD66_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HAP6145560.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28430..29107
                     /locus_tag="IVD66_001329"
     CDS             28430..29107
                     /locus_tag="IVD66_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAP6145561.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8582 a         6173 c         5242 g         9157 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga
    17221 catccgcatg cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc
    17281 caaagccatc cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt
    17341 ttccatcggt gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt
    17401 caaatccgct tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca
    17461 aatgatgaag aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga
    17521 gcttgcaatc atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt
    17581 gtacttgagt gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt
    17641 acgggatcgc acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa
    17701 cacaaaaaaa cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt
    17761 caattgtccc gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca
    17821 ggattcgttg gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt
    17881 tctagttttg attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat
    17941 tctttttcca tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct
    18001 aatttatctt cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca
    18061 tatcacactg aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat
    18121 ctttaaaatc aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca
    18181 atcatcggat ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa
    18241 acagcaggtt ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt
    18301 tccactgttt ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt
    18361 agcttttctt ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt
    18421 ccgaccaaag aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca
    18481 ttatccatga tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa
    18541 gtgacatagg cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc
    18601 gtgtagagca aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc
    18661 atcttgaatt cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta
    18721 ttccattcgt ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc
    18781 actttatctt cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg
    18841 aatacattca attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg
    18901 gtgtcgttcc aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc
    18961 attttattta acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata
    19021 tcttgtgcac ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca
    19081 atttgataag catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt
    19141 ggcagacgtc cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc
    19201 cgataaatct gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt
    19261 acttgaccag gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata
    19321 ttcgtcggaa tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca
    19381 tcaacaatca aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt
    19441 ccattcagcc ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt
    19501 cgtttagctg ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat
    19561 tttgaaggat ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc
    19621 acagtagttt tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct
    19681 tcagcgatag cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc
    19741 cgaatattct tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg
    19801 cgctggatcg aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta
    19861 gtctcttctt gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga
    19921 tcaggctgga tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat
    19981 gtctccgccg gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag
    20041 atagctgctc gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta
    20101 tctgcacgtt tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg
    20161 atgatatcca aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg
    20221 aacccgtaac gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc
    20281 tcagcaagca tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga
    20341 tcagcaatga ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt
    20401 ttcttcccga ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt
    20461 gttggctttt cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc
    20521 actaattctc cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg
    20581 actacaatct ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact
    20641 ttgtaaaaat tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc
    20701 atttcttctg gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt
    20761 ttcagttcct aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca
    20821 aggctcttca gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa
    20881 ctcacttagc tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc
    20941 tacgaataaa agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat
    21001 acgtgtgatt gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa
    21061 atgattacgc aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg
    21121 accttctaaa gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg
    21181 acgagcaagc tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga
    21241 ataaattgct ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta
    21301 actttgtggc aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca
    21361 ttgtgtcttc ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt
    21421 ttattttact ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa
    21481 ttctaaatta gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt
    21541 cgataaattc aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc
    21601 gttttcacgc ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg
    21661 ctcttctcca tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa
    21721 atgtagttta cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat
    21781 atttacatca ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa
    21841 acctagtggc tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt
    21901 tccagtgttt gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc
    21961 tctcatattt atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt
    22021 atcaactcgg tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt
    22081 tatcagaaca ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc
    22141 ctcaactttt ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag
    22201 ttccttttaa taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg
    22261 ctttgattcg ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat
    22321 tttcctctgg tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt
    22381 cagcaaactt ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat
    22441 aaaaagcctg acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc
    22501 catcttctga gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa
    22561 ccgcgttgaa tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg
    22621 cttcggcaga ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag
    22681 cattttgaat ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa
    22741 catctaatag cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat
    22801 acatgccaga ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt
    22861 taaccgcatg ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat
    22921 ttttgcatat caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga
    22981 acagctgatg attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc
    23041 cccctcattt ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg
    23101 atacaatgcc tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg
    23161 cgctgaaaac tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt
    23221 gtgtgacaac ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt
    23281 aagttatgct ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga
    23341 cttcgtctat aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa
    23401 attagggacg gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga
    23461 ggccttagaa ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt
    23521 tgacagtatt cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt
    23581 tgaccgtatc ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg
    23641 gcttaaagaa ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt
    23701 cactgcagag aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac
    23761 caaaatcgtg gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa
    23821 tgcttattgc aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata
    23881 ttgaaataaa tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct
    23941 actgctggat caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc
    24001 gccactgtga ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt
    24061 ttccaaaaac ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg
    24121 gtcaagactt cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca
    24181 agtcgacgaa cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc
    24241 agcgaaatga agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt
    24301 aaagaagcgg tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac
    24361 gctgccttta ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa
    24421 tcgctagcag cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac
    24481 aaatgatcat cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt
    24541 gccacatctt cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca
    24601 gaaatcattg cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc
    24661 tgaccttctt gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc
    24721 ttcagcacgt acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt
    24781 gtcatgatcg cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca
    24841 tcgtctgccg acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc
    24901 aagtcaacag cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc
    24961 atttcatcta ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc
    25021 gctaattctt taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat
    25081 tggtagaatt gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga
    25141 atattatttt cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt
    25201 tcatccaaac caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt
    25261 ctgcggctaa aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca
    25321 gatcataaca atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat
    25381 catcaccgag cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc
    25441 ctgtatgcag ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact
    25501 cagtctgtgc cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc
    25561 gggcgatcgg caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta
    25621 aggcctgata ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg
    25681 caaatccatg ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca
    25741 catggattac ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca
    25801 ttgtcccatt tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta
    25861 ccagaacgtg ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt
    25921 catgttctcc ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca
    25981 agacattttc tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta
    26041 acagaccctt tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt
    26101 tctcataatc ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga
    26161 tgccaaaaat gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa
    26221 taaattgagc ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct
    26281 tctgtatttt ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc
    26341 aaagtacgaa acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata
    26401 ctaggatgga tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta
    26461 gaaatcgtca atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg
    26521 gctaccatcg tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg
    26581 tccggtgttt catccaaata actgatccga acatccagca agggataact aacactttgt
    26641 tcccggttcg ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg
    26701 taaaacccta aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg
    26761 tagtgatgga acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc
    26821 tcatgatcat ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact
    26881 tctatagtct ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct
    26941 ttcgctttct ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg
    27001 ggagaataac cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa
    27061 ctgataggca gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc
    27121 ttgatattta taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg
    27181 aatctggatt tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat
    27241 caccagatga taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg
    27301 gagaactttc atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac
    27361 aaactgacac atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat
    27421 tggaatatgc cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt
    27481 gacaaattca atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag
    27541 tttcactttc aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg
    27601 ttccatagct gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa
    27661 gttttttcgt actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca
    27721 aaaaggagtc gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa
    27781 gcaagagtac gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca
    27841 gactaatatt tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg
    27901 gatccgtttc gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg
    27961 tctcgaaaca acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg
    28021 tctgcctcgt tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc
    28081 attaatccaa accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact
    28141 tttagctatt gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt
    28201 aggggatgca tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc
    28261 ttatcgtcct gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt
    28321 cattttcaca aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg
    28381 aaagaatcta gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat
    28441 ctatttattt gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca
    28501 atttatcgaa gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc
    28561 tttggtcaat ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa
    28621 tcttgaggaa cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc
    28681 ggcgcagttt caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt
    28741 cggctgtaat gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg
    28801 cggcgatttg aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt
    28861 ttctgatcaa aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta
    28921 caattatgcc tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct
    28981 ttggagaatc acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga
    29041 acatttacat acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc
    29101 taattaaaaa aggctctttg tcaaatgatg ttggtaaaga gaaatcttag aata
//
LOCUS       DACBZK010000028        29141 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.028, whole genome shotgun sequence.
ACCESSION   DACBZK010000028 DACBZK010000000
VERSION     DACBZK010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29141
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.028"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..680)
                     /locus_tag="IVD66_001330"
     CDS             complement(<1..680)
                     /locus_tag="IVD66_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6145562.1"
                     /translation="MKRVALYMRVSTEQQAKHGDSLREQKETLYEYIEQHKDLKVVNE
                     YVDGGISGQKINRDEFQKLLQDVKENKIDLILFTKLDRWFRNLRHYLNTQEILEKHNV
                     SWNAVSQQYYDTTTAYGRTFIAQVMSFAELEAQIDSERIKAVMANKIAQGEVVSGKTP
                     LGYSIENKKLVINDDAPIVIDIFNYFLSSGSLRKTVYYLGSQYGIVRDYQSVKNMLTN
                     KKYIGELR"
     gene            complement(746..2035)
                     /locus_tag="IVD66_001331"
     CDS             complement(746..2035)
                     /locus_tag="IVD66_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HAP6145563.1"
                     /translation="MGVLLFLVGIVLIIMGSSKLSEAKKLKDKTSALESKVKEYSQEL
                     NARETFISEKEKNISKLNKNLSTLENKIDILNAESQRLDDEINQKYDTSLVTIYKSVI
                     IPNIDETSSSEIKNKLSLLKIKEKDFILDGAINIPSYLNNREANNIKKKMLIPLESEI
                     TGLLNKLTISNVDSTREKIIRTFDKINKLFKNDEAEFKKELLELKLQELELNYSYIVK
                     VNDEKEQQKAIKEQMIEEEKVRREIEREKKRIDKEERQFNSEITKLMAYMQKASADVE
                     KELYADKIKELEEKLRELETVKEDVLQRELNTRAGYVYVISNIGSFGEDVYKIGMTRR
                     LEPMDRIKELSSASVPFEFDVHAMIFSEDAPTLENQLHSHFRKNEVNKVNQRKEFFKV
                     SLDEIEKVVLENYNGTVSFTKLAQAEQYRRSLELTDV"
     gene            complement(2122..2826)
                     /locus_tag="IVD66_001332"
     CDS             complement(2122..2826)
                     /locus_tag="IVD66_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HAP6145564.1"
                     /translation="MFAENLKFLREKYNIDQQELAEKLGRKSSSSISEWEKGKYTPKL
                     KTLNEIAKIFNVDIDDLMNIDLSISNQIYNILPIYNQLNDENKVATYEFASNRLEEQK
                     QENVLDFPKKEKIPTVHNSASAANPTELTYGDTVVEEEEFERVPSAADFAVPIIGDSM
                     EPVIRNGQFVFVKEQPDVEDGEIAIVELGGDGVTCKEIYKDYENQTIILRSINDLYED
                     RIVSPEQIRIIGKVVF"
     gene            3026..3292
                     /locus_tag="IVD66_001333"
     CDS             3026..3292
                     /locus_tag="IVD66_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6145565.1"
                     /translation="MDTAKKEKYTLRQLRALKGYSKEELSRKSKVTSRTIFIYENDVD
                     KMRNGKYATLEKIAKALGVRVSDIFLDPDSEKPKSITGETKQVS"
     gene            complement(3460..3690)
                     /locus_tag="IVD66_001334"
     CDS             complement(3460..3690)
                     /locus_tag="IVD66_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAP6145566.1"
                     /translation="MGKNQWVSPRNGKWAVRGEGNSEDTKLFDNKSDAVEYGKKISKK
                     QQSEFIVQKKNGQIQSKDSFGNDPIPPRDKEH"
     gene            3762..3917
                     /locus_tag="IVD66_001335"
     CDS             3762..3917
                     /locus_tag="IVD66_001335"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145567.1"
                     /translation="MSNKPKITLNGTPNLQRLADEMARIRSRHWGVTVVATIIEQKEK
                     PTQPASK"
     gene            complement(4226..4450)
                     /locus_tag="IVD66_001336"
     CDS             complement(4226..4450)
                     /locus_tag="IVD66_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004401476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAP6145568.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            4717..5052
                     /locus_tag="IVD66_001337"
     CDS             4717..5052
                     /locus_tag="IVD66_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145569.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            5285..6226
                     /locus_tag="IVD66_001338"
     CDS             5285..6226
                     /locus_tag="IVD66_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAP6145570.1"
                     /translation="MSKSTLEMSHQEWLEDRKRGIGGSDVATVLGLNKYKSPYQLWLE
                     KTGQIELKDLESEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPVIDGSGATADFLKEKYADVEENQTA
                     LPSRFDELIEQKRELKRTKKEIESSIRQVDNEIISELGKREASIGITQRNIISWKLVR
                     TRRMNTKKLAEKYPDVANDEEIYNVTESRRLTEKEIK"
     gene            6228..7118
                     /locus_tag="IVD66_001339"
     CDS             6228..7118
                     /locus_tag="IVD66_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HAP6145571.1"
                     /translation="MATNESLKNQLAEKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            7161..7961
                     /locus_tag="IVD66_001340"
     CDS             7161..7961
                     /locus_tag="IVD66_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAP6145572.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWSLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            7976..8827
                     /locus_tag="IVD66_001341"
     CDS             7976..8827
                     /locus_tag="IVD66_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP6145573.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            8824..9141
                     /locus_tag="IVD66_001342"
     CDS             8824..9141
                     /locus_tag="IVD66_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145574.1"
                     /translation="MNLTKQEKRICRQIMLQIIGDRDMDELSQQESRMVRKISKLIGA
                     DTMDRSKPLPKLNFESFTFEKYSHLREVGYSVNAIRKALGVGSSVWAKWRKENVNEVN
                     QND"
     gene            9134..9316
                     /locus_tag="IVD66_001343"
     CDS             9134..9316
                     /locus_tag="IVD66_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145575.1"
                     /translation="MIKLIGKETLKVYYVAETKAEVSRWLLKMFNKTRANASVSQKAS
                     VSETGMPEAMWISRRN"
     gene            9318..9788
                     /locus_tag="IVD66_001344"
     CDS             9318..9788
                     /locus_tag="IVD66_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145576.1"
                     /translation="MAMIPKFRAWDREKDRMIYPSTTGVCFEMNDDGISVLDIDVDYP
                     NDYGFPKIASILMQSTTLKDKNGVEIFEGDIALITHKSTNYADTYWHSYVEVFRAKNG
                     AYRIRGEHIYETELYSNRKQLTVAGNVYNSPELLKRDRFMTTTENPELLKEEQR"
     gene            9785..10327
                     /locus_tag="IVD66_001345"
     CDS             9785..10327
                     /locus_tag="IVD66_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HAP6145577.1"
                     /translation="MNKQELIDKYTAEISRLRPYCPNRHLISDQLKYGLYKEILEDLK
                     QLDEPQKPAVPKFVAEWIEYAKKKGDSLAISFKPWNLYGVEYSKTDRWIEDNQGTFAR
                     AWLIGYEVEKEPLYYVKLPVVYFNHWDLETYLMKDDRGNITIADNNDFDDMKFTESEI
                     KAIDERYWPFAVPVEEVAEG"
     gene            10324..10707
                     /locus_tag="IVD66_001346"
     CDS             10324..10707
                     /locus_tag="IVD66_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145578.1"
                     /translation="MSNLKVGDIVFYKGDEGIIREVMTDGKENFYRVDVSRKSILYLY
                     EDELDLGTQKLNDNQKMVFDYLKSNVEQGGKSVMYSIFLLGDWDSRIGAARNVDIAYC
                     GLNGKQEAEVLSAFAQWGLEQEEAE"
     gene            10704..10934
                     /locus_tag="IVD66_001347"
     CDS             10704..10934
                     /locus_tag="IVD66_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145579.1"
                     /translation="MKYEIPLSEADVQSIINGREVNKKLPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSIDDTFRLGS"
     gene            10941..11144
                     /locus_tag="IVD66_001348"
     CDS             10941..11144
                     /locus_tag="IVD66_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HAP6145580.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASNAIRKFGISILNDDRKWEEMR"
     gene            11141..11437
                     /locus_tag="IVD66_001349"
     CDS             11141..11437
                     /locus_tag="IVD66_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145581.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWTAKSKENLAVVRLVDIELINDK"
     gene            11514..11927
                     /locus_tag="IVD66_001350"
     CDS             11514..11927
                     /locus_tag="IVD66_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HAP6145582.1"
                     /translation="MQLLREVAFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            11940..12326
                     /locus_tag="IVD66_001351"
     CDS             11940..12326
                     /locus_tag="IVD66_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145583.1"
                     /translation="MWKDYVSLKELKKDLIFKKIVEWSESELILEDGTKMEVVCSESD
                     CCAWAEGEFKNVKLDAVITDIKIFDKGNRLYNGDGHSSYAEVVVYHNRNEIAKAECTA
                     NDGNGGYYYSVCALKVKEKLCVVTDA"
     gene            12818..12890
                     /locus_tag="IVD66_001352"
     tRNA            12818..12890
                     /locus_tag="IVD66_001352"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12851..12853,aa:Lys,seq:ttt)
     gene            13276..13536
                     /locus_tag="IVD66_001353"
     CDS             13276..13536
                     /locus_tag="IVD66_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145584.1"
                     /translation="MNHEKFIEKCKAIVRERIENEIADLSGAVPEFSVFIVWSCKTLQ
                     NSKALVSASLKGAPYFEITLNGDKGEIYVDTYLKKSNECIKV"
     gene            14141..14974
                     /locus_tag="IVD66_001354"
     CDS             14141..14974
                     /locus_tag="IVD66_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HAP6145585.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELKSNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFETLSDEEKDIYSSLNDNPSFVLSEEIRLLKIRQFRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKNPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            14967..16382
                     /locus_tag="IVD66_001355"
     CDS             14967..16382
                     /locus_tag="IVD66_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase B"
                     /protein_id="HAP6145586.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPENMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTTVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            16394..17923
                     /locus_tag="IVD66_001356"
     CDS             16394..17923
                     /locus_tag="IVD66_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAP6145587.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKDPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            18015..18893
                     /locus_tag="IVD66_001357"
     CDS             18015..18893
                     /locus_tag="IVD66_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HAP6145588.1"
                     /translation="MMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            18895..19212
                     /locus_tag="IVD66_001358"
     CDS             18895..19212
                     /locus_tag="IVD66_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145589.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            19261..19962
                     /locus_tag="IVD66_001359"
     CDS             19261..19962
                     /locus_tag="IVD66_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HAP6145590.1"
                     /translation="MVEWWGATIKTQSNAGRENESWGERRMSMKHKSLMPMNLQYFAE
                     GDDQKFSFDDFKSFVESNEEAQKFIQSQSQSVADKQLEAWKQNNLDKIKQDTIKEYEE
                     SKKNKSPEQIQLEKLQAEFEAEKALRVTSDNKAFVAEQIAGLELDGELKESISQFMLN
                     NLVSSDTDFTKNAVEGFTSVLNAINEKHADALKELQMKSAFGGTQQSNNQVQQNNETL
                     TNPEEQLGQILQQFN"
     gene            19977..20867
                     /locus_tag="IVD66_001360"
     CDS             19977..20867
                     /locus_tag="IVD66_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HAP6145591.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLFGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            20890..21105
                     /locus_tag="IVD66_001361"
     CDS             20890..21105
                     /locus_tag="IVD66_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145592.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            21117..21458
                     /locus_tag="IVD66_001362"
     CDS             21117..21458
                     /locus_tag="IVD66_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145593.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            21458..21829
                     /locus_tag="IVD66_001363"
     CDS             21458..21829
                     /locus_tag="IVD66_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145594.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            21822..22217
                     /locus_tag="IVD66_001364"
     CDS             21822..22217
                     /locus_tag="IVD66_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAP6145595.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            22219..22596
                     /locus_tag="IVD66_001365"
     CDS             22219..22596
                     /locus_tag="IVD66_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145596.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            22597..23205
                     /locus_tag="IVD66_001366"
     CDS             22597..23205
                     /locus_tag="IVD66_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP6145597.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            23205..23546
                     /locus_tag="IVD66_001367"
     CDS             23205..23546
                     /locus_tag="IVD66_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145598.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            23788..26577
                     /locus_tag="IVD66_001368"
     CDS             23788..26577
                     /locus_tag="IVD66_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HAP6145599.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANSFVLIIGAVVGAI
                     AVFGYFMATNEEFRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNEIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            26567..27307
                     /locus_tag="IVD66_001369"
     CDS             26567..27307
                     /locus_tag="IVD66_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP6145600.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYRNVTRKIECYYKAPSIDVVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            27304..>29141
                     /locus_tag="IVD66_001370"
     CDS             27304..>29141
                     /locus_tag="IVD66_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145601.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCEIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLAEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRLIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     SLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFTSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSAGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWR"
BASE COUNT        10360 a         4251 c         5923 g         8607 t
ORIGIN      
        1 tttcttaatt caccaatgta ttttttgttc gtcaacatat ttttaacact ttgataatct
       61 ctaacgattc catactgaga gcctaaataa taaacagttt ttcttaaact accactagaa
      121 agaaagtagt tgaatatatc tatcacgata ggagcatcat catttattac taatttctta
      181 ttttctatag agtagcctaa cggagttttc ccgcttacta cttcaccttg tgcaatttta
      241 tttgccataa cagctttgat gcgttctgaa tcaatttggg cttccaattc agcaaaactc
      301 attacttgtg caatgaaagt tctgccatac gctgtagttg tatcataata ttgttgagaa
      361 acagcattcc aagaaacatt gtgtttttct aaaatttctt gagtgtttaa ataatgtcgt
      421 agatttctaa accatctatc taattttgta aataaaatta gatctatttt attttctttt
      481 acatcttgta atagtttttg aaattcatca cgatttattt tttgaccaga aataccaccg
      541 tctacatatt cattaactac tttcaaatcc ttgtgttgtt cgatatattc atagagggtt
      601 tctttttgtt ctctaagact atctccatgt ttggcttgtt gttcagttga tactctcata
      661 tataatgcta ctcgtttcat gttatctcct ttcgaatgta tgttcttatc gttgtaaaag
      721 aaaagcccga aggctaatct ttttactaca catctgttaa ttctaatgat cttctgtatt
      781 gttcagcttg agctagttta gtaaaagata cagttccgtt ataattttct aaaacaactt
      841 tttcaatttc atcaagagat actttaaaga attcttttcg ttgattaact ttattgactt
      901 cgttttttct aaaatgcgaa tgtagttgat tttctaatgt tggtgcatct tctgaaaata
      961 tcattgcatg aacatcaaat tcaaaaggta cagaagcgct actaagttcc ttaattctat
     1021 ccataggttc taaccgtcta gtcattccta ttttatagac atcttcaccg aaagatccga
     1081 tattactgat gacataaaca tagccagctc tagtattaag ttctctttgc aatacatctt
     1141 ctttgacagt ttctagttct cttaatttct cttccagttc tttaatttta tcagcataga
     1201 gttctttttc aacatcagca ctagcttttt gcatgtatgc cattaactta gttatctctg
     1261 agttaaactg tcgttcttct ttatcaatgc gtttcttttc acgttctatt tcacgtctta
     1321 ccttttcttc ttcaatcatt tgttctttta ttgctttttg ctgttctttt tcatcgttaa
     1381 ctttaactat gtatgaatag ttgagttcta attcttgaag ttttaattca agtaattctt
     1441 ttttgaattc tgcttcatcg tttttaaaaa gcttgtttat tttatcaaaa gttcttataa
     1501 ttttttctct agttgaatct acgttagaaa tagtaagttt attgagaagt ccagttattt
     1561 ctgattctaa tggtataagc attttctttt taatattatt agcttctcta ttattcaaat
     1621 aagaaggaat attaattgca ccgtctaaaa taaaatcctt ttctttaatc tttaataaag
     1681 aaagtttgtt ttttatttcg gatgaagaag tttcatctat attcggaata attactgatt
     1741 tatagatagt gaccagagat gtgtcatatt tttgattaat ttcatcgtct aaccgctggc
     1801 tttcagcatt aagaatatca attttgtttt ctagcgttga caagttttta ttcaatttac
     1861 ttatgttttt ctctttttca gatataaacg tttccctagc atttaattct tgagaatatt
     1921 cctttacctt actctctaag gcagaagttt tatcttttaa ttttttagct tcagataatt
     1981 tgctactacc cataattatt aaaactattc caactaaaaa caatagtact cccattcaaa
     2041 acgcctcgct tcttttataa aataattgtc aaaatcatat aaacccttac cgaagttgac
     2101 ggctccggca tgggaatttt tttaaaatac aacttttccg ataattctaa tctgttctgg
     2161 cgatacaatt ctatcttcgt ataagtcgtt tatagaacgt aaaatgattg tttgattttc
     2221 gtaatcttta tatatctctt tacatgtaac tccgtcacca cctaattcca caatagcaat
     2281 ttccccatct tctacgtccg gttgttcttt aacgaatacg aattgtccat tcctgataac
     2341 aggttccatt gaatcgccta taataggtac tgcgaagtca gcagcacttg gaactctctc
     2401 aaattcttcc tcttcgacaa ccgtatcacc gtaagtaagt tctgttggat tggcagccga
     2461 agccgaattg tgaacagttg ggattttttc ttttttagga aaatctagga cattttcttg
     2521 tttttgttct tctaatcgat tacttgcaaa ttcataggta gcaactttat tttcgtcgtt
     2581 aagctgatta tatataggaa ggatattata tatctgatta gatatagata aatcaatatt
     2641 catcaaatca tctatatcaa cattgaatat cttagctatc tcatttaagg tttttaattt
     2701 tggtgtatat tttccttttt cccattcgct tattgaggat gaactttttc ttcctagttt
     2761 ttcggctagt tcttgttgat caatattata cttttctcta agaaacttta gattttcagc
     2821 gaacatagta acacctcctt gagttaattg taacaccgtt tcggaaaaaa tgtaacaggt
     2881 ttcttagaaa atattttagt gtttttaaag aagtatttac gcaaaataga aatcgatttc
     2941 aggaaaactg aaatatgcac ttgacttcgg aaaaaccgaa gtatataatt tagtcagaaa
     3001 gttaaagaga ggaggcgaat aaaatatgga taccgcgaag aaagaaaaat atacattgag
     3061 acaattaaga gctttaaagg gttattcaaa agaagaactg tcaaggaaaa gcaaagtgac
     3121 atcaagaaca atatttattt acgaaaacga tgtagataaa atgaggaacg gaaagtacgc
     3181 cactctagaa aaaattgcta aggcattggg tgttagagtt tccgatattt ttttagaccc
     3241 tgattcggaa aaaccgaaat caataacagg tgaaacaaaa caagtcagct aggaggtgtg
     3301 aatagtggaa gagaagaata taaaagtacc gactcttgaa gaatatacaa aaattgttgt
     3361 cgaaacagac gagcagaacc cgaaaacaat cgcagttatt acggcgaatg atattgaatc
     3421 atgcgaaggt tttcgagttc gaatgacccc tagatatgat taatgttctt tatcacgtgg
     3481 aggtatagga tcgtttccaa aactatcttt tgattgtatt tgtccattct ttttttggac
     3541 aataaactct gattgctgtt ttttagaaat ctttttacca tactcaacag catctgattt
     3601 attatcaaat agttttgtat cttcggaatt accttcacca cgtacagccc atttgccatt
     3661 tctaggagat acccattgat ttttacccat aacaattcac ctcgctttca agttaattct
     3721 attaagaggt gaaaagaaaa caaactgatg gaggtgagat tgtgagtaac aagccaaaaa
     3781 tcactttgaa tggcacacct aatcttcaaa gattagcaga tgaaatggct agaatacgtt
     3841 ctagacattg gggagttact gtggtggcaa ccataattga acaaaaagaa aagcccacac
     3901 agccggcaag caagtagtgg gcaccataga acaataatat tatatcacac actcgccact
     3961 tccgaaaaga ggagttgctg ctctcctttc aagtttgcca aagtccacgt ttcttcattt
     4021 tggcaactcc tcttcttgga ggtggtgacg gcgagagacg aaggagggat gacatgaagg
     4081 aagaatcaaa aatagggatt ttgaatgaga acaattacac aagattaatt attgaaacag
     4141 aagaagggga aaaagtagca gaagttacat tgaccgatgc aactcctgct gacggttatc
     4201 gtattcgatt aactcctaaa tatgattaac cttttggtgg gtgtggatcg tttccgtgac
     4261 tatcacggct ttgaattttt ccatctctgc catgaataaa tagctcagat ccttgatttt
     4321 tagaaatctc tctagcgatt tttactgctt ctgattttgt attagtatgt gcagtcgctt
     4381 tagaatttcc agcacctttg acattccaac caccattgga attaggtaca acatgttgat
     4441 tttttcccat agttttcacc tccatttcta tagaaatatt ttatcaaata gaaatggaga
     4501 aattcaataa acgaaaggag ggatcaaatg acattacaag agcatcaaca cttgatgcga
     4561 aaactaaatc aggaatacca cgaggaaatg aaacctagat tgctagggga acaatggcgt
     4621 gaacgccaga agaagtggtt agaaataaaa aagtgactca gccgtccaaa gcaatgagtc
     4681 acaaaccaaa aattatacct aaggagattt tatcacatga ataagaaaat tgaaaatctt
     4741 atcgaagaat tgaaacgtga atgccaaaag caaggtgttt ctattatttg tacagcccaa
     4801 aaagaagggg aacttaaaag tctcgtttat ggtgagacaa cagaaatttt actttgtctt
     4861 gctatgcaag aagaacattt agatgaaaat ctcccattgt cagcacatat tatgcgtaga
     4921 attgctgtgg atgcttacga acaagcgaaa aatgaagaag aaaatcaacc ttcaaatcat
     4981 acttttgtta ttaataacaa ggaagattta gctgatgtga tgactcgtat tctcaagggg
     5041 gaatttcaat gatgaatgaa aaaacaattg atctactcat tattttattt ttcacgttag
     5101 tgattgtagc gaaaagttat gtaatctttg gcttgttatt cgcaattacc atgcttgtgc
     5161 tttgcgtgtt agcaagcaga aaagaggtta aacatgaacg agttagcaaa tcttgacaac
     5221 tatttaactg atcctgatta tgctaaacca ccatatgaag cgccaattga tgaggaggat
     5281 gaagatgagt aaatctacct tagaaatgag ccatcaagaa tggctcgaag accgcaaaag
     5341 aggtattggt ggctcagatg ttgcaaccgt acttggatta aacaaataca aatctcctta
     5401 tcaattgtgg cttgagaaaa cgggtcaaat tgaattgaaa gatttagaaa gcgaaccagc
     5461 ttattggggt aatgttttag aagaagtggt tgctaaagag tttcaggaac gtacaggcaa
     5521 aaaagtacgc agaagaaacc aagtatttga acatccatta catccatttt taagagcaaa
     5581 tattgatcgg gaagtagtgg gagaaaatgc cattctggaa tgtaaaacag ccaatcaatt
     5641 tctcggaaaa gagtgggaag gtgaagaggt accgcttagc tatctctgtc aagttcagca
     5701 ttacatgaac gttttaaaca aagactattg ttatatcgct gttttgatcg gtggacaaaa
     5761 attcatttgg aagcggattg aacgagatca agagctgatc gatacaatca ctgaacaatt
     5821 agtagagttt tgggaaacga acgttcttgg aggtatcgag cctgtaattg acggaagtgg
     5881 agcgactgct gacttcttaa aagaaaaata tgcagatgta gaagaaaatc aaacagctct
     5941 accatcacgt tttgatgaac ttatcgagca aaaaagagaa ctcaagcgga cgaaaaaaga
     6001 aattgaatca tctattcgtc aagtagacaa cgagatcatc agtgagctag gtaaacgtga
     6061 agccagtatc ggtatcacac aaagaaacat tatcagctgg aaacttgttc gtacaagacg
     6121 gatgaacacg aagaaactag cagagaaata tccagatgtc gcaaatgatg aagagattta
     6181 taacgttact gaatcaagaa ggctaaccga aaaggagatc aaataatatg gcaacaaatg
     6241 aatcgttaaa aaatcaattg gcagaaaagc cacagaaaca agttgcacca ggacagttag
     6301 ggcttaaagc tctaatgaat acaccaacaa tgagaaagaa atttgaagaa gtacttcatg
     6361 acaatgctaa tgcttttatg tcgaatgtta tgactcttgt atctaatgac agttatcttg
     6421 cagatagtga accgatgtct atcatgagtg gtgcgttaac tgctgcaaca ttaaatcttg
     6481 ggctagataa gaatttaggt tatgcatatt tagttccatt caatagtaaa aacaagcaaa
     6541 caggaaaatg ggaaaagaaa gctcaattca tgcttggcta taaaggatat atccaattag
     6601 cccaacgatc aggtaaatac aaagcattaa atgtgatcga agtttacgaa ggagaactaa
     6661 aaagctggaa ccgactgaca gaagagtttg agtttgatcc aaatggtaga acgtctgatg
     6721 aagtcattgg atatgttggc tatttcgagt tactgaatgg attcaaaaaa actgtctatt
     6781 ggaccaaaca agaaatcgaa gctcatcgga ttgctaacaa taaagatcgc gataagacaa
     6841 agttaagtgg tgtgtgggca tctgattaca atgcaatggc acgaaaaact gttttgagaa
     6901 atcttctttc taaatgggga atcttgtcca tcgaaatgca agaagccacc acatcggatg
     6961 agagagtcca aagggttcaa gaagacggca gcattattgc tgaaacagaa gttgaagaag
     7021 atattcctga aagaaaagaa gcagaggtta tatctgaaga aaatgaagat gtacaaactg
     7081 gattatttga tgcatctaat ccgccgttaa acaaataatg agggagcttt ctcccttgct
     7141 tttctagagg agaaatacga atgaacacag gatatgtcaa attacatcga aaagtgatga
     7201 attcattcgt ttggaccaat ccttatatgt ataaattatg gagcttgtgt ttgatgaaag
     7261 cgagtcatga gaatcgcaag atacttttta atggaaaaga gatacaagtg aacagcggag
     7321 aattcgtcac agggcgcgat gctatcacat ctgagatgaa cgaaggcgtg aaacgtgaac
     7381 atcaagtgaa cagcggttct gtatggagat ggctaaaaca atttgaaaaa aacggaatgt
     7441 tgaacatcaa atcaactacg aaatacagcg ttatatcaat aaaaaactgg tctttgtacc
     7501 aaagcagtga acaacaaatg aacatcaaac gcacaacaag tgaacaacaa gtgcacacaa
     7561 acaagaatga aaagaattat aagaatgaaa agaataataa aacatcatcg tcgcaaccac
     7621 gcaaaaagcg tgtttacgac accgactcag tttactacat tctcgcggag gagttattca
     7681 aacagatttg tcagaatcag gaaatcaaaa agccgaatct gcaaagttgg gcagataaca
     7741 ttcggaaaat gatcgagatc gacaagcgga ccgaaaacca ggtacgggga atgattgaat
     7801 ggagtcagca caatgtgttt tgggcatcga atattttatc tgctaaaaaa ttgcgagaaa
     7861 aatacgacac aatggcagcg caagcaaatc gtgattataa aacaaaacaa actaaaacgc
     7921 ttgaatacga gaaatttagc acagatgagt tgcctatttg agaggaggcg taggcatgga
     7981 aactgttggg gaaatcatgg aaaagctgat acagaaagtg cttgtccaac gtggcgaatg
     8041 tcctgaatgc ggacagcctt tgtatggatg gcgtacgaag aaccctgatg gctcagaacg
     8101 ttgtaagcca acctgtatgc aatgtgggta taaagcattg cgagttcagg aagacttaca
     8161 aacagaacga atttacaacg agagcctgaa agcaagagca atcaattttt tcaaaggtgg
     8221 ttctgttgtg cctaatcaag cgttgtttga ttgcacattg cagaattatc aaattgtcga
     8281 tcaagaaaca agacaagcgg ttgaagtaac caaacgcttt gttaattcag tcttgttagg
     8341 aaatccaagt caccttgttt taactggaaa acaaggaaca ggtaaaagtc acctagcgat
     8401 ggcagcggct tgggaagtct tgaagcgatc aaactacgat aaaaaaatct tatttatcgg
     8461 gttacaggaa atgctggatc aaatcaaatt ttcgtacaac aatcctgaac tcagaaaaac
     8521 gattgaggga tcgttgattg cagatatcaa aacagcggat ttagtcatca ttgatgatat
     8581 cggttcagaa ctaggaaaag atgcatcaga tagtcgagcg tttggcataa acacgctaaa
     8641 ttcgttcttg gatgcacgac agaacctagc aacgattatc acaacgaact tgcttggtga
     8701 agaactgaaa aaagcttacg gtacgagaac aatatcaaga atgtttgtca actctgatgg
     8761 atttacgatg gtattttctc aaacagcaga caagcgcata aaaccagtca aaggagcgat
     8821 cgcatgaatt tgactaaaca agaaaaaaga atctgtcgtc agataatgtt gcaaattata
     8881 ggtgatcgtg acatggacga attatctcaa caagagagtc gaatggttcg gaagataagt
     8941 aagctaatcg gtgcagatac gatggatcga tccaagccat tacccaaact gaattttgaa
     9001 tcatttacgt ttgagaaata tagccatctg agagaggtag gctatagtgt aaatgctatt
     9061 cgaaaagcac ttggggtagg aagtagtgta tgggcaaaat ggcggaaaga aaatgtaaat
     9121 gaggtaaatc aaaatgatta agctaatagg caaagagacg ctcaaggttt actatgtagc
     9181 ggaaacaaag gcagaagtca gccgttggct attgaaaatg tttaataaga ctagagccaa
     9241 tgcttcagta agtcagaaag caagtgtatc agaaacaggc atgcctgaag caatgtggat
     9301 ttcaaggagg aactgagatg gcaatgatac cgaagtttag agcgtgggat agagaaaaag
     9361 acagaatgat ttatcctagc acgacaggag tttgttttga aatgaatgat gatggtataa
     9421 gtgtgcttga tattgatgta gattatccca atgactatgg ttttcccaaa atagcttcaa
     9481 tcctcatgca atctaccact ctgaaggata agaatggtgt ggagatattt gagggggata
     9541 tagcgcttat cactcataaa tcaacgaact acgccgatac ttattggcac agttacgtag
     9601 aagtttttag agcaaaaaac ggagcctaca gaattcgcgg tgaacacatc tacgaaacag
     9661 aattatatag taatagaaaa caattgacgg tagcggggaa tgtttataat tcaccagaac
     9721 ttttgaagag agatcgattt atgactacta ccgaaaatcc agagttattg aaggaggaac
     9781 agcgatgaat aaacaggaat tgattgataa atatactgca gaaatatcta gattaagacc
     9841 ttattgccct aatagacatt taattagcga tcaacttaaa tatggtcttt ataaagaaat
     9901 cctagaagat ttaaaacaac tagacgaacc gcagaaacca gcggtgccta agtttgtggc
     9961 ggaatggata gaatacgcta aaaagaaagg cgatagtcta gctatttcat tcaagccgtg
    10021 gaacctctac ggtgttgagt atagcaagac tgatagatgg attgaagata atcaaggaac
    10081 gtttgctcgt gcttggctaa ttggctacga ggtcgagaaa gagccgttgt attatgtgaa
    10141 gttgccagtt gtgtatttta atcattggga tttagagacg tatctaatga aagatgatag
    10201 aggaaatata acaattgcag acaacaacga ttttgatgat atgaaattta cggaatcaga
    10261 aataaaagca attgatgaaa gatactggcc atttgctgtg ccagtggaag aggtggcgga
    10321 aggatgagca atcttaaagt tggagatatt gttttttaca aaggtgacga aggcatcatc
    10381 cgagaagtta tgacggatgg aaaagaaaat ttttataggg tagatgtcag cagaaaatct
    10441 atactctacc tgtatgaaga cgaattagat ttaggtactc aaaaactcaa cgacaaccag
    10501 aaaatggtgt ttgattatct taaatcaaac gttgaacaag gtggcaaatc agttatgtat
    10561 tcgatattcc ttctaggtga ttgggactct cgaattggag cagcaagaaa cgttgatata
    10621 gcttactgtg gattaaatgg taagcaggaa gcagaagtcc tatcagcatt cgctcaatgg
    10681 ggattagaac aggaggaagc ggaatgaaat acgaaatacc actaagtgaa gcagacgtcc
    10741 agtcaattat taacggtcgg gaggttaata aaaaacttcc tgatggtact gaattagtca
    10801 tcagacaaag ttatttgaaa gatatggcag ctccagtatt aattgatcgt tttaacgtga
    10861 ctgattctgt ggtagagaac catttaaaag aatttcgatc aagtatagac gacactttca
    10921 gattagggag ttgattgaca atgaacaaca gacatcgcag aataacaaaa ctaagaaaac
    10981 aggaactgaa tgtactaaag acaaagtttg aaaaagaata tggaatttca gcagaagaaa
    11041 catataaagt ggcaagtcag tgtgttgctg atgcgagtaa tgctattcgt aagtttggga
    11101 tttcgatatt aaatgatgat cgtaaatggg aggaaatgag atgaaactaa aagacggatt
    11161 ttacgctagt agtcacggca tcggcggttt aatgctagat atgccgacaa agaatcctaa
    11221 aacacgtaag aaaccaaaag tcaaagtcgg tgacatggtt cgctgcgaag cagaagggtt
    11281 catctatcca tttcgtggat atgtagaaca cgtctataat cactcagcaa tcattcgtat
    11341 tgaaaacacg atggaatgtg ataaatggac agctaaaagc aaagagaatt tagcagtggt
    11401 gagattggtg gatattgaac taatcaatga caaataaaaa agccggatcg ctccgactga
    11461 ttcaataaat tccacaagtt tattatatca cataaaaggg gcggtttgac ttgatgcaat
    11521 tgttacgaga ggtagctttc aaacagacaa gatgtaatgc gagagatgtg ctgaagaact
    11581 ttcggcgttt ggagcggatg gcaggtcgct ctttgataga tattaagtcg ccgattatta
    11641 cggacatgcc gaaggcaccg aagcacggca ataaggcaga agacgcgatc attcagatga
    11701 tggatataga agcagagaga gacgcgattt tagcggcttt gatggcgctt agtctgatta
    11761 gtcgtcagat actctactac agcttttgtg tgccagatag cttctcaaac tacaggatta
    11821 gccgtgaagt gggttattca gaaagaagca tacaacggat gaagtcggaa gctctgatag
    11881 agtttgcaga agcatataaa catgggaaaa taattgctta taaataggag gactatataa
    11941 tgtggaaaga ttatgtatca ttgaaagagt tgaaaaaaga tcttattttc aaaaaaatcg
    12001 tagaatggtc agagagtgaa ttaattttag aagatggaac caaaatggaa gttgtatgta
    12061 gcgaatcaga ttgctgcgca tgggccgaag gtgaattcaa aaatgtaaag cttgatgcag
    12121 tgattacaga tataaagatt tttgataaag gtaaccgtct ctataatggc gatggacata
    12181 gttcttatgc cgaagtcgtt gtttatcata atcgaaatga gattgctaaa gcggaatgta
    12241 cagcaaacga tgggaatgga ggctactatt acagtgtctg tgctttaaaa gtcaaagaaa
    12301 aactttgtgt agtgactgat gcataaaaaa tggcggtttt ttggcggaat gatggcggtt
    12361 tttagctatt taccagtgat attatggtag tgtcgaaaga ttagtgatag gtctgagaca
    12421 aaataaaatg taagggagga aatctccctc atcgtttaat taagcttcga tagacagcag
    12481 cggaaatatt aagaataagg atgtgaattt taactccttc taaattgttc ttattatcta
    12541 tcatccgttg ctgtctattg ttattatgtc actgtggcgg aaagggtaga cgcttaaaaa
    12601 taaggtcaat acgtcgaggg atagccttaa cgttttatga tttgaccatg caaggttcga
    12661 ttccttgcca gcgacttaga cgaaaggtag cttaaatatt aaccacatca acatcgtcag
    12721 cgagttgata aaggtaacta gcagactcta ggatttaagc cagtcttacc gattagtctg
    12781 ttatagtagc aagcttgcta gaggtagctc ctctggttga cgtgcagctc agttggtaga
    12841 gcgcctgact tttaatcagg aggtcgccgg ttcgaatccg gtcacgttaa taaagaacct
    12901 acggaaacaa tcaatcttat cggatgccga ttggttggct gaattaagca gtgtgtctgt
    12961 gaatcagtta ataggcataa aatactagca cagacgtgtg ccactctcag gtgtaggtta
    13021 ggagagaaac attagcaacc gagggttgga aatgggcgct caaagtacac gagcaaggcg
    13081 aggtcgatag taatcgatgg aatcggtgta ggttgctatt acataattga ttgggttaga
    13141 ttgagttttg ggattcggta caaatgaatc gtcaaatgac tcaagcacag gatcggaaac
    13201 gtccctgcct gtgcattaca tattagatca ctcgttgagt ggtcttttta ttttagaaaa
    13261 gagaggattt tgaaaatgaa tcatgagaag tttatcgaaa aatgcaaggc tattgtacgt
    13321 gaaagaattg agaatgagat tgctgaccta agtggagcag tacctgagtt tagtgttttc
    13381 atagtctggt catgcaaaac actacagaat agcaaagcat tagtcagcgc tagcttaaaa
    13441 ggagcaccgt attttgaaat tacgttgaac ggggacaaag gtgaaatcta tgtagatact
    13501 tatctcaaaa aatcaaatga atgtatcaaa gtctagcagg tgctaggctt tttctttaca
    13561 taaaggagga atgatctcat gaaacaatat accgctaaag atttcgagga aatgaagcga
    13621 ttaaagaagg actatgaaga agttgatatg gagctaactg ttggagtcat tcaacgaaga
    13681 ctgcgggtcg gattagagac agcaaaggct atttacaatg atctaaatgc tattgaagag
    13741 aagaatggct aatgaggaac tactggtata tatcgctaac taatgaatat cctcgaacca
    13801 ttgatgattg ttcagtgcgt gttgtgcgtt ctgtacaaat caaagggaag tactctattg
    13861 tcgaaatggg gagagaagca gaaccatgtg agattgatgc gtgcaagctc gtttattgcg
    13921 gtcatggttt ctatgatgaa ccaaacattc aaaataatat taacaagaat ttgagggatt
    13981 agaatgcaag aaatggctta aaaatctcca atcaggacaa atcaagttag acaaagtttc
    14041 cgatttaaag atattaattg aagcagatct aatgttgaaa gatattgaaa attagaaaac
    14101 aaaactcaac ctaagaagat tgcgaggtgg tgtgtattga atggcaagac aacgtgatcc
    14161 aagacgtgat gaagccaaaa gaatttggtt agaatccaac ggagaaaagc agttaaagga
    14221 aattgcatct gaattaaatg tttcagattc tcaggttaga aaatggaaat cgcaagacaa
    14281 atggagcgct gaattgaaaa gtaacgttac caatggcaaa agtaacgtta ctaatcaagg
    14341 tggcgctcct attggtaatc aaaatgctaa aggtaacaaa ggaaatagcc gagcttctcc
    14401 gccagtgggt aataaaaacg ctttgaaaac aggcgagtat gaaaccatat tttttgagac
    14461 actaagtgat gaagagaagg acatctattc tagtctgaat gataatcctt cttttgtttt
    14521 gtctgaagaa atacgtctac ttaagataag acaatttcgt atgatgaaga gaatccaaca
    14581 agctgaagct ggactaaatg atgaagaagt cgaacgattg cagcagctaa gaaagattaa
    14641 aaatccgatt gaaaaaaatg gtaaaaagct agaaatcaag cgtgaggtta tgcaagatgt
    14701 gcagattagc agaaaaaaac atcgcaaaat tgatgatatt ctttcaattg aagattcatt
    14761 gactcggatt agcaaccagt tagctaaagc catcaagcaa atgaatgaac tttatatgaa
    14821 tgaatacaga actgatttaa ttaaagctca gactgataag atccaagctg agacaaatga
    14881 aattggcgga aataattcag gtgaagaaat agaagaatgg aaacaggcag ttttaaatgc
    14941 cgcaaacaaa cgggcggtga aagaaaatga ataatgaatt tattcctttt gctgatattg
    15001 gttctgccat tgattattac tatgataaac cagtagcttt ttgccaagat attttgcatt
    15061 tgaatcctga tgaatggcaa gaaaatgttt taaatgattt agctgaattt tcaaaggttt
    15121 ctgttcgttc tggtcaagga gttggaaaaa cagcattaga agcaggagca atactttggt
    15181 tcttaacgtg tcgaccctac gctaaagtaa tagcaacagc tccgacaatg aagcaacttt
    15241 acgatgtact ttgggcagag gtagctaaat ggttaaatga tagcttgatc aaaaacttac
    15301 tgaagtggac aaagaccaaa atttatatgg ttggtgattc agagcgttgg tttgctacgg
    15361 ctagaacagc gactaaacca gaaaatatgc aaggttttca cgaggaccat atgttgattg
    15421 tggtagatga agcttctggt gtgtctgatc caattatgga agctattctt ggtacgctat
    15481 caggttttga taataagctg ttgatgtgtg gaaaccccaa taatattgaa ggtgtttttt
    15541 acgattccca caattcagac cgtgataaat acagagttca taaagtatca agctatgata
    15601 gtaaacgtac aaacaaagac aatatagaaa tgattcttaa aaaatatgga aaagaaagtg
    15661 atgttgctcg tgtccgtatt tttggagaat ttcccaaagg tgcgttggat tcatttatca
    15721 gtcttgaaac ggttgaattg gctacagaaa aacaaattag tgattcttta gtcaataaaa
    15781 caacggttgc tcatattggt gttgacgtag ctcgatatgg tgatgattct acgattctct
    15841 ttcctagaat tgctaccagg gcattggagt atgagaagta ttcaaaacgt agcaccatgg
    15901 aaacaacagg atatgtcatc aacatggcca agaatctaat gagtcaatat ccgagtattg
    15961 ataaagtgat gattaaagtc gatgacactg gtgtcggagg tggtgtaacc gaccgcctag
    16021 aagaacttat agaagacaaa cattatcctt ttgaggtgtt tggagtgaat aacggttcaa
    16081 catcagaaga cgatttttac gataatttag gtactcaact atggggaaac atcaaggaaa
    16141 tgttagaaga aaatatgaca gcaaatctta acggagaaca gcctgttatt gaattgcctt
    16201 ctgatagttc gttaatcaaa gaattaagta ctcgcaaatt caaaatgaca agtagaagtc
    16261 gtatacgttt agaaagtaaa gatgatatga aaaagcgaaa tattggtagt cccgatattg
    16321 ctgacgcact ggctttagcg ttttatgagc caccaagtca ctatcaattt attcaatttt
    16381 aggaggtgag cttttgatta gtacagtatt atctttagag agatataaga agctacgtgt
    16441 taaatatgca acacaaattg aagatggaat gtttgatccg aatggtttta tagaagatat
    16501 gaaaccattt tttgctgatc gcgaaagaaa atatctagct tatactagcg aaaagaatga
    16561 aatagataat agaccaaagc ctaacactga tattgtaaaa gttaataata aacttcatgc
    16621 tggtatgtat tcaattgtcg tagaccaagc agtcaatcat tttactggta tacctatcaa
    16681 atgggattac gatgtatcgg aacaaaaaag aacactcatt caaagattaa aagataaatt
    16741 cttaaaaaat gatatagaac ttccgacagt tccagaagct tttaacaaat taacaagcaa
    16801 tcttgattcc atgagattcg caatgcttga ttctgaaact gcaacttttc aaggagcttg
    16861 tggagtagct ttccgattgt tagagcctgt ggaagaagat gatggttgga agttaagagc
    16921 aagtaatatt gaaccttgga gagcagaaag atatggaaat gccggaatct atatcaaaga
    16981 aaagtatgac tcttaccaga aaaaattttt tcaagaaatg aaagttatga caagaaataa
    17041 aattctgaca tatgcttgct atggtgattt gaattttgtt acaagcggaa cgttcaaaaa
    17101 aattgatgag accgataacc ctttggggac gattaccttg gcagaattta aaaataatac
    17161 gaatcgttat tgtgattttg aagtagctga ggaaattgga gatgcaattg atcgtgcttt
    17221 gtctgatcaa caaaacgaaa tcgaacaatt taagcttgcg tacatgcttg ttactggcac
    17281 aacaatgagc aaaggcactg ctaaagaaat gatgaatcag ctagggatta tcaacttaaa
    17341 agaccctact gcaaaagctg aatatgtcac aaaaaattta gcaaaagatt tcaatgaata
    17401 tcatatggat ctattgaaaa aacagtttta caccatttgt aaagcaatcg attttaacga
    17461 tgaggtgttt aaatcaaaca gttctggaga agctcgcaag tggcaaatca ttagcctaga
    17521 agcgaaaaca aatactaaag agcaatattt tagagaagga ttgaaagaat gcgcagaaac
    17581 aattgctgct tttcttaagt ttcatgacaa agtagaaatt gagcctgaaa aaattatttt
    17641 tactttctct agatctttgc caactgattt aagttattta gctgaagctt tacctaaact
    17701 tgcaccatac gtatccaaac gaactattca gagccaaatt ccatttgtaa cagatgttga
    17761 ttatgaaaat gaaatgatgg aattggaaag tggaagtgct tatccagata gtgaatacaa
    17821 ttttggcgga ggtggcaata gtgacgatag aaacgaagta ttggaccaaa cgtcgagaac
    17881 tggaggatca agcaaggctc aaacaagaaa atcagacact taaaaaatta actagtgtat
    17941 ttcctgaagc actgaaagag atacaagcaa aactattatc acaagctgac ttacacaata
    18001 tcacttatcc agaaatgatg gagttttata gtacaagtaa tcagaaaaaa tatcgtgaat
    18061 atgtggaaaa aaattataag tcattaaaaa tgtatgatgc aaaatacaaa gagtttatcg
    18121 atgaattttt tccaccattt gactatgcaa aagtcaatcg cttattacaa atacgatcag
    18181 atgtatttaa aattcttgca gaatatgcga tggatgcaga tgtgaatcaa tatttttctg
    18241 atcgcttaga ggaaattctt caaagaacat attcttctaa tgctaatgtt tttgttcaac
    18301 ttttaaacgt tgatatacca aattatttac cagaaaatga aattaaacat tatttgaact
    18361 atccatggtc aggaaagaca ttttcaagaa gactttgggg aaatatttca tcgcttgaac
    18421 agaaactctc taatgctatt gtaaaaagtg ttgctagtgg agaaggcgtt atacacgcat
    18481 taaacaccat gagattagac tcagaaattt gtgacatgtt taagttagaa gaatcaaagt
    18541 ataacaaagc gatagaaaat ctcgttcgaa cggagtatgc aaaatttgca caagatggta
    18601 ttgaaaaatc atatttagaa acaggtattg aggaatacaa cgtattgact gcaaaagatg
    18661 agagagtttg ccggatttgt ggaggaaagg caagtaagaa tccctataaa ctgaaagatg
    18721 ctgtcatagg tgaaaatcga gcacctttcc atagtcgttg tagatgtacg gatgttccta
    18781 atttaccaaa attaggaaag gatattgatg aagaatatga ccgtttattt ggcgatttat
    18841 tagatgagtt tgcacatgat tcttttggaa ttaatttgaa acggaggaag tagaatgaaa
    18901 gatttttttg aagcagtact aacaattaat gtaaatgctg atattgcaga agcctacaaa
    18961 acagctattg agtctgagaa ccatcctaat ggcttgagag accattggaa tggcaattat
    19021 gcctacgtgg ttattggcga tcaaactgtt aattatcaag ataatactcc agttgataag
    19081 aataccgtta atttaacgat tcaattatta tctcattcat taccaaattt aaaagaaaca
    19141 gttgattggt atgaaaagat gggatgtatt gttgttagaa ctgactacaa agaaggaaag
    19201 tctagtaatt aggctttttt attttgtccg aaatgacgtt aaactagcgc aatactgggc
    19261 ttggttgaat ggtggggcgc aactattaaa actcaaagca atgcggggcg tgaaaacgaa
    19321 tcgtggggcg aaaggagaat gagcatgaaa cacaaatcat taatgccaat gaatttgcaa
    19381 tactttgccg aaggtgacga tcaaaagttt tcttttgatg acttcaaatc ttttgtggaa
    19441 tccaatgaag aagctcaaaa atttattcag tcacaatctc aaagtgttgc cgacaaacaa
    19501 ttggaagctt ggaaacaaaa taacttagat aaaattaaac aggataccat caaggaatat
    19561 gaggaatcta agaaaaacaa gtcacctgag caaattcaac tggaaaaact acaagctgaa
    19621 tttgaagcag aaaaagcgtt gcgtgtgaca agtgataata aagcatttgt tgcagaacaa
    19681 attgctggat tagaactaga tggagagtta aaagagtcta tttctcaatt tatgctaaat
    19741 aatcttgtta gttcggatac agatttcact aagaatgctg ttgaaggttt tacaagtgtc
    19801 ttgaatgcaa ttaatgagaa acatgcagat gcattaaaag aactacaaat gaagtctgca
    19861 tttggtggaa ctcaacaatc gaataaccag gttcagcaga acaatgaaac attaacaaat
    19921 ccagaagaac aattaggaca aattcttcaa caatttaact aggagagtga aaaattatga
    19981 aaaaaacatc tttaaataat ttagagtatt tggatatttc accagcgatt aatgctatgc
    20041 aagtaccaaa tacacctttt ttaagctatt tatttggtgc tggaaaaaca gagccagcaa
    20101 actcgacaga aattaaatgg cgtgaatatg atatcaacaa cgatgattct tctgaaaaac
    20161 ttgagggcgg agaatatcca gatgctgaat caggtcgaac ttggtttaac aactatactg
    20221 aaatttttag aaaatcaacc tctgtatctg gtacattaga tgctattaat gtgaatggag
    20281 tcggaaatga attaactaat caagtagcac tacgtggtat ggaaatgaaa attgatttga
    20341 accgaaaatt gattactggt gtaaaagctg atgaaaatgg ttctaaaggt cgtcgaatga
    20401 atgggatttt gaacttgatc aattcagcaa ataaggcaga aacagccact gcgggtgcag
    20461 taacaagaaa agatatcgat actttattta aattgatgta tgaaaaaggt tatatgggag
    20521 aaaaactatg cttgatttct ccagatatgc aggagttaat gactgatgag ttagatggaa
    20581 aatcaacaaa aattgttcag ttcggggaaa gagtaacttt tggattgcaa attggaaata
    20641 tcgtgtctaa ttacggtaca ggtattgctc tactagaacc atcattgcca aaaggaacaa
    20701 ttgccgcaat cgatactaat tatgtgaaac tacgtccatt acgtgaatgg agagcagaag
    20761 aacttgcaaa aacaacggat tctagacgta tcggtcttgt aggtgaatac tctcttgaat
    20821 acaatgcttc aaactctggg gcaattttaa atttaaagtc tgaataaaag ggagttagta
    20881 ctcccttttt tgataggagg aattacagtg gtaaaaaaag atgaaactaa aaaagatgaa
    20941 gtcgtgaaat atagagtagg taaaactaaa aattttgttg ggtttgttca tcctaaaact
    21001 cgtagattta tcacagcaga ttcaaataac gaatttatca tttctataga tgataaagaa
    21061 gcaattgcaa ttttggaaga tgcaattgat gttaatgaaa tttaggaagt gatctgatgg
    21121 atgaatcgct aaaaacggaa atcattgagt ctacaaaaga agattttcca gatttgagtg
    21181 aagaacgcat aactaattta ttagaaataa ttttgctaga aattgaatca tacaacactt
    21241 gtaaaaatga tatttcatgg gaaaagttaa aaagcgtgat tagtgaagtg ttgtataaaa
    21301 taataaaaaa tgaatcagaa aaaacagtat cttcagttag acgtggcgat acaacgatta
    21361 gttatgcttc aacaacaaat gatgttagtg agttacttct aggctatggt gatttgatac
    21421 gaagagttat tggttgtgga ggattggagt ttttttaatg aatgaagcag atattttaga
    21481 aactacttat gaagatagtt gtattattga aagactgacg gacattgaag attctaatac
    21541 aaatattact attcaagatt acaaaaaagt atatgataat cctatttctt gcgctctttc
    21601 acaaggtcaa atcgatggac tagcagtcat agaagatgga gagatggtaa atgtttcaac
    21661 tgacacatat aaattatttg ttcatcctaa gattaaacta aaaaaaggag atcgaataac
    21721 aataactcaa aaggccagtg gcttaatttt ttctctattt gctactaagc ctttttacta
    21781 tcctagtcat tgtgaagtga atttgatagg aagtgagaaa aatgggtaat ctcaaatatg
    21841 aatcaaatgc agaaaagatc attgagaatt ttaaaaatat gactgtaatt gctcaaaaag
    21901 aaggaatatc cttcgttaac gattcaatga ataaagtcgt tagtttagct aaaccattaa
    21961 ctcctgtaaa atcaggtaat ttaaggcgag gatatcgtgt agtaaaagct agaaaactat
    22021 caagcggtcg aattgttgga gcagttataa acaatgaaca ttattttaaa tatgtagaag
    22081 aaggtcatag gactaaaaat ggtggctttg tcaaagggaa attcatgtta actcgtgcaa
    22141 cgaatcttgc aaatatgtct tatattcctc gaagatttaa acaaatggca ataaaaatcg
    22201 ttaagaaagg aaagtaacat gaaagatgaa atcattgctg caatcagtag caaattaaaa
    22261 gaaatctatc ctgatgggac aatatatctt gattcagtta tgcagtcaac taaagatttt
    22321 tatttcgttt tatcagtaat ggaatctgga actgaaaatg taggaattga tattcaaaat
    22381 gtttctttct taattgatat tgcattgatt gataataaac ctaatagaaa tttaattaat
    22441 gaattagtct cacgttgtgg gacttttttt aatacgatta caatcgatga gcaaatatta
    22501 tttccaaaag cctatttacc tgatgaagca gatggtgttc aacatattcg ttttacatta
    22561 gaatttccac aatatattga atggagtgaa agataaatgg gagaaaaaag aagtaaaacc
    22621 ggaattattt ctgtcgaaaa acctacttgg tttcctttgg aagatgagac agggaatttt
    22681 ccggtatatg gtactgcgtt gccaatggga acagcagtaa gtatcaaacc aacagctaat
    22741 tatgaaacaa cacaagatta tggggattca gtggttcaag atcaatttac agcttttggt
    22801 ggtgcagaag ttgaactgga agcaaatgga tatactcata aagttttatc tacaattact
    22861 ggagggaaaa ttgttaaagg tggtgccttg cgttctggag aagatattgc gcaagatggt
    22921 gcgtttgcat atagacgtaa aaaatcgaat gggaaatacc gttatacggt cttttataaa
    22981 ggacagtttg ctctagattc agatgaaaca tcaacgattg aaggaagtaa agtaagtttt
    23041 actcatccaa cttggaaggg ttcatttgta gatgtaccag gacttggata tatgtattca
    23101 gttgatgaag atgatgaagg cgtggataaa gcaatgatcg gaaattggtt tacaaaagta
    23161 gcaattccaa ttgaagaagc agaactttca ggaggtacag aataatgtca aaatatcaaa
    23221 caacgattaa attaacgaaa aaagatgaag aaggtaaata tgagcaagta caatttaaat
    23281 ctgctgaatt tttaccagga acagttgtag aagatgctgc aggagttatg gaagaaatgc
    23341 aaacagcgac tgataaacaa tcagttaaaa aagctttaag tcgtgcttat tcatttattg
    23401 cagatacttt atttgaggga caatttactg gtgaagatta ttgcaaagga attgatgctc
    23461 gtgagattgc ctcattgaca ggaaaattat tgaagtctgt tactgcaggt tttgatgaaa
    23521 cttatacaga gacgaaaaaa aagtaagtga ggcgctcaag tcaccttcat ttaagtattc
    23581 gattacttac cgagaattag atataaagac gcaattactc gaagcaggtt ggacgttacc
    23641 agaaattgaa cgtactgact tggatgagtt aatgcgtctt tttgctttta gagatgcggt
    23701 aaaagagcat gaagatgttg agtactatga taatttcact caattttagg aggtgatact
    23761 ttgaataacg atgacctaat tctgaagatg atactagatg aatctggttt tactgccggt
    23821 atgaataatg ctgtcaaaaa gttgaactct tttgatgaaa caatcgaaag aaaaagtaga
    23881 aatagtggca gttcattagg tagtatttgg aaaatatttg ctggaagttt tctagctagc
    23941 ggagtaacta gaatcgtagg agctggcttt gatctaatca agggttccat aagtggagcg
    24001 gttgatcgag tagatacgat gaataacgct ctacgaaatt tccaaaatat gggatttagt
    24061 aattcagaaa ttatgaagaa tatcggaaag aatgggcttt tatctcaagg tattcaagga
    24121 cttcctactg ctttgaatga tgcgataagt catgttcaac ttcttgcttc ttctacaggt
    24181 gatttaactc gttcaactca aatatttaaa gctttaaatg atggaattct tggtttcggt
    24241 ggttcaactg atcaagttaa tgaagctgtt attcaattat ctcaaagttt ctcaaacgga
    24301 aaagtagacg cacaaacttg gaactcaatg atcaacgctc aacttggacc tactctttct
    24361 gctattgcta aaaagatggg aattacaatg ggagatctga aagaaggttt gtctcaaggt
    24421 aagatttctg ttgaagaatt ccaaaatcaa ttaatagaaa tggataccaa aggtggcgga
    24481 ggacttaaat cattaagtca aatcgctaaa gattctacta agggaattaa aacctctata
    24541 caaaatgcaa aaacagctgt tacacgtggt gttggtgagg taatagaagg attaaataaa
    24601 gcattagtag attcagattt aggtggattt aagggaatta ttgataaagt gggcagttca
    24661 atggaatcgt tcttaaaagt aattgctgca aatattccta cagcagtatc atttttaagt
    24721 aatttattta acgaaattca aaaatttggt tctgctttga aattcatgat gccctttctt
    24781 gttcctgcag ctaccgcttt tggagcgttc atgtttcaac ttaaaggtat accagcaata
    24841 ataaaaagct tcaataattt taagaatgcc ataattggcg ttggaaattc attaaagatt
    24901 atgggggcaa tagctgctgc taattcattt gttttaatta ttggtgcagt cgttggtgca
    24961 atagctgttt tcggttactt tatggcaacc aatgaagagt ttagaaacaa ggttatatct
    25021 atttggaatg atgtgaaaga ttccgtaatt ggtgtattaa aaaatataaa ggactgggga
    25081 attgatactt ggaattctgc taaagaaatg gcatcaaatg cagttgaggg tgtcaaagat
    25141 gcttggtcag gaacaaagga atggttttct aacacctgga aaggtattaa ggatggggcc
    25201 acaggtttat ttgataaaac agtagagact tcaagaaatg cagtcgatag tgtaaaaaat
    25261 gcatggtcta atatgaagaa atggttttct gatacttggc aaagtataaa agattcagcc
    25321 agagaaaaat ggaatgaaat taaaggttct attatgtcgg ttgctggtcc attgattaca
    25381 ggtataaaga atgcattttt acatgttact ttttatctag agaccttatg gaataattta
    25441 gttgagattg gtaaaaacgt ctttgagatt ttaaaaaatg ttatacttgc gccggttttg
    25501 tttattacct ccatgatttc tggtggatgg gaagaaacaa aaaataatat gattgctgtt
    25561 tggaataata ttaaagaaag tgccataaat atttgggaat ctataaagaa tatatttgta
    25621 agttatttta caaatattta ttttgctgca ctcaatattt ggacagggtt caagcttaca
    25681 ttgataaata tttggaatga agtggtaaat caagctaaat cgatttggtt aaacataaag
    25741 tattttttta ttaatctttg gattgatata aaatattttg caattcagaa atggattgaa
    25801 ttgaagtttt ctattattca aacttggatc gatttaaaat ataatgccat tactacttgg
    25861 aataatatta aacagttttt caaagatact tggaaaaata ttaaagatac ggcatacaat
    25921 acgtggattt ctataaaaaa taccatgatt aatacatgga ataacattaa ggactctttc
    25981 tggaatattg ttactggaat tgttaattct gctgaaaatg catggacaaa tctaaaaaat
    26041 ggtgtttcaa atgctattaa tcgggtaaaa gaaatcttta attcgttaag ggaagtcaat
    26101 ttatttgaaa ttggcaagaa catcattgat ggacttataa atggtgtaaa agaaaagtgg
    26161 aatgctttga aagatactat caaaggtatt gcaggtaata tcaaaaattg gattaaagga
    26221 gctttagata ttcattctcc atcaagatgg atgcgtgata tggttggtaa aaatattgtt
    26281 caaggtatta tcgttggtat tgataaagag caaagtaagt tagatcaaac catgacaaat
    26341 ttagtaaaaa caccgtctgt tcaacctgta gtaaatggaa taagtcacct accaattaca
    26401 caaacaaagc aaaatatatc tgctagtgaa acaaaagaaa ttcatttaca tttaaatgtt
    26461 tatggagatt tacctgattc aatggttcgg aagattacca caaaaattaa aacagaattg
    26521 acaagacaaa tgaaacgaga tgctggtgca gtaggaggaa cattatatgc aacttaagag
    26581 aggacaattt tttattaatc aacattattc ttctgaattt aatgtgtata ttcaaaacag
    26641 gcctgcttct gtttcagcta gtcgagtaat tgaattgaga gagcgagaag gaaatgattc
    26701 tatcattatt gataaaggct attacagaaa tgtgactaga aagattgagt gttactataa
    26761 agcaccttca attgatgtgg tgcaggagtg ggaagatcga atcactgaat ggttagatat
    26821 gtcgtcttat agtgatttta ttctttacta tgatgaacaa tatatttatc aagctgtagt
    26881 aatagaagga cctgaattta aaggaacaag aaaaacagga aatattgtcc cttttgaatt
    26941 tacagtgagc attcgaccat ttaaggaaaa ttacaatggt agatttacta ttcgacaaac
    27001 agaaactttt gaaatttata acccagagaa gtattcttca aaaccgctta ttaaattgag
    27061 tggttctgga gatgcttctt tttatattaa taaggacaaa tatgatttga aatcgttgga
    27121 cagagaatta tttatagatt ctaaattaga agaggcttac cgaaaattag atggtaattt
    27181 agaacatcag gatcaagtca ctttattttt agattttcca tttttatatc ctggaaaaaa
    27241 tgaaattaaa tggacgaaaa atattcattc atttgaaata atgcctaggt ggtggagaaa
    27301 agtatgaaac caagaatata tagtcctact gaaacagatt tctcaacgaa tggcttagga
    27361 attttaaagg attgtacaag atgtgaaata tatgaagtag ctaatggaaa atatgaatta
    27421 gagttggatt atcctttagg aactagattt gatgaatatt ttgaaaatga ctatcaaata
    27481 aaagcaaagc caaacgatca agaagagtat catatctttt ttattgatga taaagatata
    27541 gatacttttt taaatacagt aactatttat gctcagagtc gtacaaatcg acttggaaga
    27601 cgggtagtca ctcttgcgga agtagactct aaaactggtc aagaagcgat atcaattatt
    27661 gaaaccaaaa tggataaaaa atctgacata cgactttatt ctgatattac ggccgtttct
    27721 agcacaatct ttgaagcgag aaatgtttta aattgtattg ctggtgaaca aggatcattg
    27781 cttcaatatt ggggtggaga aattaaacgt gaaccattta agctttcttt gttaaagcga
    27841 agaggtcgca ataatgttgg aacgattcgg tatggaaaag atatgtctgg tttaaaggtc
    27901 aaattagatt ggacaggtat aaaaacaaga cttattccat atgctgatcc tcaaagtgag
    27961 gtaggtacga ctaatcgaat ttatggttcg ccagtagata gtgcctatat taataactat
    28021 cctgatgtgt atacagagca tgttcagttt acagaagaac aaggagtaaa agacattaag
    28081 agcttaaata aaatagctaa aaattacttt aaaacgatca atcctggctg tgataagcct
    28141 aaagtttcta ttacggttga atttgataag ttgactgata gtgaagaagc gaaagaattt
    28201 gcgaagatta gaaattatgg tctgtttgat acatttaaaa tatatcataa aaaatataat
    28261 atttatcttg aatcaaaggt tagtggacta caatacgatt ctttatctga aaaaactttg
    28321 aaattagaag caggagacat tcaagttgct ttttatcagc aacaagctgt aactattcag
    28381 gataaattaa aagattatgc aacgaataat tatatgagtg attttaatga ttatgtttct
    28441 tcaatgatta caggtcaagg cagtgcagga ggatatgtaa gtttatggcc aaaagaaaaa
    28501 ccttccaaca tctttattat ggataatcca gatttagaaa aggcaagaga agtactaaga
    28561 atgaataaaa atgggattgc tttttctaag aaaggatggc gggggccttt tacttcagct
    28621 tggacattag atagtatatt taatgccaat tttatacaaa ctggattaat caaagcagat
    28681 atctttcaaa attcttttaa caagactgga gatgtattga aattagttaa tggactactc
    28741 caaatttgga acaacaaaaa gaaaataatg gagttaacta aaaaaggaat ggaattttgg
    28801 aattctaagg gttcaattgg aacgattgga acaactgatt ctgctggtaa tccttttcct
    28861 ggggcttcta ctccaacccc tattgaagat aattctttag ttattcgtac aaatggagac
    28921 ggcaaatata ttttgatttc tcctaaagta ggaaaaggat tagttttatt aggaaatggt
    28981 aaagcaattt attttggaga cttagatgta caaggaaaac ttacagttaa aggaaaagaa
    29041 ataattcctg gacaaggtgg tggtccatcg ggaggtggag aatctactgg tgggtatcct
    29101 agtgaattaa aaacagatgc agaaaagaga gcttggagaa t
//
LOCUS       DACBZK010000029        29043 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.029, whole genome shotgun sequence.
ACCESSION   DACBZK010000029 DACBZK010000000
VERSION     DACBZK010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29043
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.029"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(105..629)
                     /locus_tag="IVD66_001371"
     CDS             complement(105..629)
                     /locus_tag="IVD66_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6145602.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="IVD66_001372"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="IVD66_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HAP6145603.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="IVD66_001373"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="IVD66_001373"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HAP6145604.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="IVD66_001374"
     CDS             complement(2351..3031)
                     /locus_tag="IVD66_001374"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAP6145605.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="IVD66_001375"
     CDS             3157..4026
                     /locus_tag="IVD66_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP6145606.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="IVD66_001376"
     CDS             4052..4567
                     /locus_tag="IVD66_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145607.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5177)
                     /locus_tag="IVD66_001377"
     CDS             complement(4614..5177)
                     /locus_tag="IVD66_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6145608.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="IVD66_001378"
     CDS             complement(5232..5411)
                     /locus_tag="IVD66_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145609.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="IVD66_001379"
     CDS             complement(5488..5997)
                     /locus_tag="IVD66_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145610.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="IVD66_001380"
     CDS             complement(6093..6473)
                     /locus_tag="IVD66_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP6145611.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /locus_tag="IVD66_001381"
     CDS             6803..7552
                     /locus_tag="IVD66_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HAP6145612.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7736..9013)
                     /locus_tag="IVD66_001382"
     CDS             complement(7736..9013)
                     /locus_tag="IVD66_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145613.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCHYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="IVD66_001383"
     CDS             complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="IVD66_001383"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAP6145614.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(9935..10879)
                     /locus_tag="IVD66_001384"
     CDS             complement(9935..10879)
                     /locus_tag="IVD66_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAP6145615.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(10881..11567)
                     /locus_tag="IVD66_001385"
     CDS             complement(10881..11567)
                     /locus_tag="IVD66_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAP6145616.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            12041..12361
                     /locus_tag="IVD66_001386"
     CDS             12041..12361
                     /locus_tag="IVD66_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAP6145617.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            12515..13420
                     /locus_tag="IVD66_001387"
     CDS             12515..13420
                     /locus_tag="IVD66_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6145618.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            13417..14190
                     /locus_tag="IVD66_001388"
     CDS             13417..14190
                     /locus_tag="IVD66_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP6145619.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(14371..15795)
                     /locus_tag="IVD66_001389"
     CDS             complement(14371..15795)
                     /locus_tag="IVD66_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6145620.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            16006..16452
                     /gene="nrdI"
                     /locus_tag="IVD66_001390"
     CDS             16006..16452
                     /gene="nrdI"
                     /locus_tag="IVD66_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAP6145621.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(16517..18499)
                     /locus_tag="IVD66_001391"
     CDS             complement(16517..18499)
                     /locus_tag="IVD66_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6145622.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(18513..19409)
                     /gene="murQ"
                     /locus_tag="IVD66_001392"
     CDS             complement(18513..19409)
                     /gene="murQ"
                     /locus_tag="IVD66_001392"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAP6145623.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(19412..20473)
                     /locus_tag="IVD66_001393"
     CDS             complement(19412..20473)
                     /locus_tag="IVD66_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAP6145624.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(20684..21211)
                     /locus_tag="IVD66_001394"
     CDS             complement(20684..21211)
                     /locus_tag="IVD66_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP6145625.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(21278..22780)
                     /locus_tag="IVD66_001395"
     CDS             complement(21278..22780)
                     /locus_tag="IVD66_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAP6145626.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(23038..24159)
                     /locus_tag="IVD66_001396"
     CDS             complement(23038..24159)
                     /locus_tag="IVD66_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP6145627.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            24285..25226
                     /locus_tag="IVD66_001397"
     CDS             24285..25226
                     /locus_tag="IVD66_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAP6145628.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(25376..26272)
                     /locus_tag="IVD66_001398"
     CDS             complement(25376..26272)
                     /locus_tag="IVD66_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAP6145629.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            26541..27881
                     /locus_tag="IVD66_001399"
     CDS             26541..27881
                     /locus_tag="IVD66_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6145630.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            28099..28542
                     /locus_tag="IVD66_001400"
     CDS             28099..28542
                     /locus_tag="IVD66_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAP6145631.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
BASE COUNT         8365 a         6014 c         5220 g         9444 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct attttttata
     7741 gtaattcctt cagatacttt cttgcctcat cattgaaacg cagtgattct tctaacttct
     7801 gataatattc caacgcttgt ttctgagctt cagtaaaacg ataatgtttt cctttccatt
     7861 tgtcgattgt ctcttgcaca tttccagatt ggatatcttt cactactagt tgccattttt
     7921 cttttgagac tgtacggtct ttcttatcag cagattgtat agcttctcgt tctttacgca
     7981 atacttttaa aaaaccattt ctgactatcc gaggaatgct gtcgaagaac ccttctgtaa
     8041 aaccatagtg acaatattgc ttccaaataa atagatagat ttttggttgg atgaatcgtt
     8101 ggtttttcgc aaaatattcc atctgagcag tgacttctgg tgttcgttga cgttttgtct
     8161 ttctcaacac ggaaataaat gtttcaaaat aagcattagg atgtactggc acttcttcat
     8221 atacgatgga ttgccaatct ttacgtaaaa atgcgcgata gttgatcaag aattcttcta
     8281 catcctttac taattcttct gcaaagtcgt caaatagttc tttttttatc tgtcgctttt
     8341 ttgactgccc attgatgtgt tcacttattt tcttgatttc attttccaat gcttgataat
     8401 ccgctatgta aatcggcatt tctacttggc gaaattctgc gagccgctga gctaatttta
     8461 tatccggtaa atatggctgt ttcatccgac gattttggta caagacaaaa cagtattttt
     8521 gccatagtcc ttcaggaaaa tcgatattct tctgcttaag ccataataat tcgtctaagg
     8581 ccagatcaac ttttgtcatt ccctgatgga tcgaagctgc cactgtcgga gagacatgca
     8641 ggtgatcggc aaagtggttg atgcctagtt ttaggatctt tccggttttt ggcgatttaa
     8701 cgatgtattg cacttttaat tctctaccac actcacaata caatttttgc tggcttcgtt
     8761 ttgttcgaaa aaacggattg atcttgaagt cagaaaacac ccaatctgtt gcagctaaat
     8821 aatgttcttc cataaaacga gagctgatta gatatcggcg gtgcttatcg actagttccc
     8881 gctgtttttt cgttaatttt gcatagatct cccaacgttg actgcttgtg tattgtttag
     8941 aaattttgat gggatagctt ttgctgattt cttttggaaa ccattcttca aagacggatt
     9001 gccattcttc cacggctgtt tctttccttt ctaattacaa aaagctggct actaacataa
     9061 cgttagcaac cagccagtgt ttcttgctaa attagtgagt tgttccggca tttccggaaa
     9121 tatcttcttt attttctact gctgcttcaa ctgcataagt caaagaagaa gcaatgtctt
     9181 ctaaagacat agaaggcgta cccactggac gatcgatcac ttgatcgggt gagaatggca
     9241 cgtggatgaa cccacctcga attgccggga attgtgtttc gatcaaatga agcaaacgat
     9301 acatgatatc attgcagaca aatgttcctg ctgtataaga gatgtacgct ggtagaccat
     9361 gatcttgtac attttttgtc attgctttga ttggcaatga ggtaaagtaa gcggctggac
     9421 cgttttcttc taaagccgta tcgaatggct gatttccttc attatcaggg attcttgctt
     9481 ctgctagatt gattgcgaca cgttcgaacg agactgctga ccgcccacct gcttgtccga
     9541 cacagatcac gacatctggt tggtgctgtt ggatggcttc tttgactact tgactgcttt
     9601 tttcgaatac ggtcggtact tccactttga tgatttcagc accgctgatt tcatctggca
     9661 ttttttttac tgcttcatag gctggattca ctttgtcccc accaaatgga tcaaaacctg
     9721 ttactagtac tttcatctgt tgttcctccg tccgattgat ttaacatatg gttatctttt
     9781 atcataccat tttccttgaa cagcgtaaat aaaggaaaca atagtttaaa taacataaca
     9841 gatcaaactt aatatattct tataaaaaaa tagtgttcca ctacaatgtt agaagaggtt
     9901 gcgacaatta ttctgtcaca acccctctct tctattattt aaatagaatc atataagcaa
     9961 tttggaaaac tagcataaat aacgcaataa acaactggtt tttgatcact ccgtatttgt
    10021 ctttcatctc cagcatcgct acaggcacga tattgaagtt agcagccatc ggtgtcagca
    10081 gggtcccaca aaaaccgcaa gtcaatgcaa ccattcctat taacgctgga ttcgctccat
    10141 gactaaatac gaatggtgca ccgatcccaa ccgtcatcac ggtgatggcc gcaaatgcat
    10201 tccccatgat taccgtaaat atcaccatgc caagagcgta aatgatgatg ccgatgttca
    10261 catttccttc tggaacgatc gtacctactg cattggaaat cactgtccca actccagcgc
    10321 ttgtaaatac cgcacctaga gaagctaaaa gcattggcaa catgcttaac ggccctactg
    10381 tgcccagcat atctgctgca tcatctaaaa atgtacttgg tcgattatct cgagaaaaga
    10441 acatcaagat tagcatggct gcaaaaacac cgacgcccac gccgactaaa gcacctaaat
    10501 tggtaaatag agcaaacaag atcgcaaaga caccgatact caaagctgga ataaaaattt
    10561 tcattcctag tttgtctgac attttttcca tatattcttt tgatggaagc cggctttctc
    10621 ctttgctgac tttcttagca attgctggta tggtcatcgc aaagatcaag ccaccgttca
    10681 cgattgccgg aagccatctt cctcctgcaa taactacccc taagaccgtc cagaaaaagg
    10741 ctgacccata acgatgagga ttggttttat ctgttaaatt tcttactcca gtgtaaatca
    10801 atacgagtcc catcacgata taaaggatct ccagtaattt atcgcctaat aaaatatcag
    10861 gatttgtaaa aaagtccatc ttattgcccc tttcctggat aatatttctt cgctaatttc
    10921 ttttctttaa gatagaagta gacacttgcc acaactaaag ccgtgatagc cactggaact
    10981 tccactaaag caagctgtcc caatgttacg tcatatccta gatctttcag tgttgattgg
    11041 actagcaacg cccctgctcc tccgatgaat agtacttggc caaagaacca gcagacattt
    11101 tccatagctg aagccatacc ttttagttct tcttcatgct taggatggac ttctaaccct
    11161 tttgattcga tggtccccaa tgccatcggt aaaatgattg gacgaacaaa tccagcaact
    11221 ccaccaaaac tcacgttaaa agccgcaaag atcattcgaa agatcccata aatatctaca
    11281 atcataccag cagatacttt cttgaatcgc ttgatcaagg aagccgctga ttctttcaga
    11341 ccatttcttt caagcgttcc tgttgccaac ataatgatga taaaaatcgc catcccgcga
    11401 ttgtttacaa aacttgtacc taaaagttct aacattcctt gaatgccaag accgccagtc
    11461 aaagctgtaa caactaaagc aaccattacg atcaatatcg agtctaattt aaatgcaaac
    11521 ccgagaataa caatcaagac gcctaaaagg ctaagataat tttccatata ttttcctcca
    11581 taaaatgaca atattttttt aattataaag caaaacacat aaaaaatata gttgttttct
    11641 cacgaaatag acactatttt taaatatttt tcgttatttt tttatcacaa aaattatctt
    11701 acttattgta aggtaaagct ttttttaatt tattgcccga taatatatag aaataaggtc
    11761 tagttactgt tttttttaaa tgattaataa ataacaactt ctttctatga aattgcaaag
    11821 cattcatctt cttttccgct aacgatatat ccgtcagtgc ttggtacact ttactaaaaa
    11881 gtatgagatt gccgatatct ggataggtgt gctatactac agaaaaagat atacaatctg
    11941 ccaccgggta ggataaagag gatgatcatt ccattaggtc tttgaaggga tgattttcct
    12001 ctttttgtgt atttttttat agttaaggag gaatgtaagt atggcatgga tggaattaat
    12061 catagcagga attttggaag tattctggtc aacgatgatg aaatggagtg atggtttttc
    12121 taaaatcaat tattcttttt acacagtgat tggcatgatt gctagttttt actttttgtc
    12181 aaaggcaatc aaaagtttgc cgatgagtct ctcttatcct atctggacag ggattggcgc
    12241 agttggttcg gtcataattg gtgtggtctt gtttcatgat aagctgaatc tttccacttg
    12301 gttctttgtg gggatgctac tcatcagtat cattggcatc aagattacta gcggccacta
    12361 gacacttgga ataagtactg atcagaaaaa ataagccttt ttatttaata ttcaattttt
    12421 ttatgaaaaa ataagaaata agtccaatga cctagcgact tctccactca tcaggtgtat
    12481 gcttgtacta tctatagaaa aggagtgaat atttttgaaa agtctttcgg tccaagaatt
    12541 atccaagaac tttggtcaca aacaagccct cagcgatgtc agttttagct tatcccctgg
    12601 caaaatcgtt ggattagtag gtcctaatgg cgctggaaaa acaacgatca tgaaagctat
    12661 tttaggactg atccattact cagatggaac aatctgtatt ggtgaaaatg agatttctcc
    12721 ctctagtcat aaagggttgg aacaagtagg agcattgatc gaatacccgg gtatctatcc
    12781 attcttaaca ggctatgatc atctgaagtt attctctgaa accaacgatg tatctgctat
    12841 cgacactatc gtgaatcagc tcaagatgga aaagtacatt cacaaaaaag cgaaatccta
    12901 ctcgttggga atgaaacaaa aattgggaat tgctcttgcc ttactgaacc atccgtctat
    12961 cgttatttta gatgagccga tgaacggttt ggatccacaa gcaacaagag atgtgcgaaa
    13021 aatcattacc gacttggcta ctcagggcac ctctttcttg atctccagtc acttactcag
    13081 cgagcttgaa aaaatggtcg atgagctgat cctgatcaat caaggaaaga tcatcaaaca
    13141 atgtacaatg gctgaattga accaaacagc gcaagatttc atcgttatct ctacaacaaa
    13201 tgatctagct gctcgaacga tcttgacaga agctggatat actttggaag atcctgataa
    13261 aatcaagctt ttaaaagaaa acgaagaatt attaggaacc gtgatccagc tattgtctgc
    13321 acaaaatatc catgtgacag acgtccagca tctgacgaat gatttggaat cttctctatt
    13381 ggaaattctg gattcagtaa agggggaaga agaaaaatga cattgcttgt aaaacaagaa
    13441 ttatttaaat tgatcaagaa aaagtcaact gctgttttat ctgttctatt agttgttttg
    13501 ctcataggaa cagcacttct agccaaaaaa tacacgacga tcattgatcc agttgaaatg
    13561 actgctcagc tttttagtgc cacatcttgg attgtcttta tcatgattgc agctgcaagc
    13621 acgatcattt cgatggaagc acaatatggt acattgaaaa atctccttta tcgaaagtat
    13681 tctcgaggag aaatattagt aagcaaatgg atcacattag ttatttattc tgtttattta
    13741 taccttttag ctattattgt cactgtgttg atgaaactga ttcttttccc ttcgatttcc
    13801 ttcacggaga aggtttctac tggtcaaaca ctgatccaaa gcttgttcac ttatactttg
    13861 ggtagttata tcggtttatg gctgatttta agtttagtgt tgatgattgc ttgctttatc
    13921 aatagttccg gcgcatccat ctcagcagga atcgtctttt attttgcttc gtcaatcata
    13981 tctggtatcc ttattgcact catccaaaaa tgggagtgga tcaaatggaa tccgatcagt
    14041 atgttgaatc tgcaaaacca aattggaaac gaagagatca tgaagcaatt gactcatctt
    14101 tctactaatc aaatgctatt cggtaattta gcttacatcg ttttgttctt agcattagga
    14161 tatctcgtat ttaagcgaaa aaatgtatga tgactcatca aaaaagaggc tgtgaaagag
    14221 acgttcagcc ttattgccga ttggctgtct cttaaacacc gtttattctg aaaaaggagc
    14281 tgtgacaaca tttgtgtcac agctcctttc ctagtatgtt tttgaataaa cgacaggctc
    14341 acaacctctc tttatacttc ttttatactt ctatacgtga agcatcccag tggcaaataa
    14401 aaccattgca atcactccga ccatcgtcac acctataagt aaaatcttat ctaagtggat
    14461 atgttgtaca ggctcgtttt gctccttacg tgctttgagg taaaaataaa tgcctggcaa
    14521 gaaaagaaca agaacaagca ttacttcatt aaaggctacg actagcatag cccatacttg
    14581 aaaggcactt gctaaaagcc ctactaaaaa ttggacccat tctttccgct gataagaaag
    14641 tttcatttgg tacaatccta agaaaagcca cgtgaagaaa atagctgctg taccaagtgt
    14701 gtaagcaaag ttataagcac tgtcagtgaa taataatgaa agtaaaaaga cattcgtaca
    14761 taacgtcgtc aatacgatag cataagttgg tgccccattt ttgttgagtt ttccccatgc
    14821 tttaggcaaa agtccgtctt cagccatgtt tcccattgtt tcaatcggta agatcgtcca
    14881 tgagagccaa acaccaacta aagaaatgat caaaccgccg ttgatcacga ctgctcccca
    14941 tttaccaacc atcatttcaa acacatagcc catagcaggc tgcgccttga tcgtttgcag
    15001 ctgattcatc gtcattgtcc catatggaag catggaaacc aagacgtaaa taataatcaa
    15061 gccgaatatc cctagaatcg ttgctttccc aacatctgat tgtttttttg ctcgtgaacc
    15121 tacgacagag gctccttcaa taccaacaaa tacccaaagc atcaccatga tgcaactcaa
    15181 tacttgactg gaaaacggga tcggctgtcc attcgcattc aatataatgt cgctagaaaa
    15241 gttatcaatg aattgttgga tcgaaaacgt gctgatagct actacaataa ataaaaataa
    15301 tggcactaat ttacagaatg tgacgatagc attgacgaaa ctagcatttt cgactccccg
    15361 attcactagc catgcatatc cccataaaaa gactgtactc atcacgatcg atgccagatt
    15421 ttgcccacct tcaaatactg ggaagaaata tcctaatgcg ctcatcaaca atgttgcaaa
    15481 agctacgttg cctaaccagc atgtgagcca gtaaccccaa ccgctgataa aaccagcgaa
    15541 acggccaaaa ccttcttctg cgtaactaaa gatcccgcct tttaaatctg gacgtttttt
    15601 attgatatta ttgatcgaca aggagagcat caacattgct gttcctacga gtacccaact
    15661 gaaaatagct gggccgccag ccgatccgga gatgtccgtc ataataccaa atacgccacc
    15721 tccaatcgct gaaccaatta ctaaggcagc aagtggaatt aaaccaattc cttttttctg
    15781 ttgctctgta tccatgtaag catcctccaa aataaaaccg cttttatcaa aaagtataac
    15841 aaaccttttt tatttttact taattaataa aaactttaat agaaatataa ttctaccggc
    15901 ttttttctca ttatacaagc aaagcgccta gtccctttcc aaattacacc accaaaaaac
    15961 ttaaaaaaga tgctatacta aaaggaaaga attggaggat gatccatgaa cattttatat
    16021 atatcgattt caggaaatac gcgtgccttt gccaaacatc tagcagaata tgctgaaaaa
    16081 atgcatgcag aagatcctgt caatcctgaa gttactttaa aagaaatcca tgaaaatagt
    16141 gattttacga aagaaacaga accatttttt actttcgttc ctacttattt agacggcgga
    16201 aatggtttag ataacggtga tacagaaatc ttgaccgaaa cgatgcgtga atatctggaa
    16261 catgaagaca atcataaact ttgtcttggt gtagtcggta gcggaaataa aaacttcaat
    16321 aatcagtatt gtctaacagc caaacaatat gcacaaacat ttggctttcc tttcttggca
    16381 gattatgaat tacggggaac accatctgat gtgacacgaa tttatcagat tttagcagaa
    16441 aacaataaat aataaaaaag aagaagctga aaaatagatt tcagtttctt ctttcgtttc
    16501 tattgtttct atcatattaa gctttgacat ccatcacagg tgcttttgct tttgctttac
    16561 ctgttttttc caagacaaag ttttttacac gatccatatt ggttaccaag acgatcatgg
    16621 atgtttcttt gcctgctgct ttgatcgctt ctaagtcagc ttctgctaca agcgtatcag
    16681 gtgtcacttg ctgcccttct gttactttca catcaaatgg cgtaccgcct aagtcaactg
    16741 tgttgattcc catatgaagc aagatttcta aaccatttgg cgttgtgatc ccaatagcgt
    16801 gtttcgttgg gaagacagag ctgactaccc cagtaactgg agaatagata tgtccgtttt
    16861 ctggttctac aaagtagcct tcacccatca tcttttgtgc aaaaactgga tcacttgctt
    16921 tatctaaaga aacaactgtt ccgtcagcaa ctgatgagag gatagtcaca ctttcagctg
    16981 aagtttgagg tactactttt tcaggcactt catttactgt ggctgtttca gtcgctaatt
    17041 cttctttttc taaacggtct ttaggaatac cgaagaagaa tgtagcaacg aagccaccag
    17101 cataagctgc caataatcca aggatgtagc ctaaccattt accgtcagag atcaatggga
    17161 tcaaagcggc tcctgaaggt ccaatagcga tagccccgac atttccgatc attccgatca
    17221 ctgccccgcc gatacctcca ccgatacaag cagtaataaa tgggcgtcct agaggtaatg
    17281 ttactccgta aatcaatggt tcgccgattc ctaggatccc gactggtaaa gctcctttga
    17341 tcatttctgt taattcttta tcttttttgc agcgaatcca taatgccaat gctgcaccca
    17401 cttgtcctgc accagccatc gcaagaattg gaagcaatag cgtacgacca gtttcatcaa
    17461 tcatttgcac atggattgga gtcaaaattt gatgcagtcc gaacataacc atcggcaaga
    17521 ataatgtgcc tagaacgaag ccggcaaatg ctccaccaac gccaagtacc cagttgatcc
    17581 caccgaccat gccatcagaa atgaaacctg ctaaaggcat gatgaagaaa atttcaatca
    17641 gaccgatggc aatcaacgaa agagttggtg taacgatgat atctaccgca tcaggtacta
    17701 ctttatgcag ttttttctca acgattgaca atagccaaac agcgaagatg acacctagga
    17761 tcccaccttg tccagctgca agagcttcac cagtaaataa gtttttcagt ggtgcttccg
    17821 gattcatccc tgtcagcatc acaacggccc cgataactcc accaagagtt ggtgttgcac
    17881 caaaaacttg tgcagcattg atacctgtat agataactag gtagctaaac atcccgtttt
    17941 tcaagatgtt catcacatcg atatattgtt gccatgttgc tgcatcaagt gttccggctg
    18001 tgactaagtt tgctaaaact gcggcaatcc ctgccacgat cccagtaccg acaaatgcag
    18061 gaatcattgg cacaaagata ttagaaatgt cttttaatac cgatttgatt ttagatggtt
    18121 tttgtttcga tttttgtgcc gctttcattt cttgtgcccg ttcgtttaca cggtcttttc
    18181 cagatgctga tgaatttgct gtagctgtac ttacagaaga aagtttttct cctaatttca
    18241 cgcctgccaa atcaaccatt tgctgtgcta ctttgttcac tttcccaggt ccgatgatga
    18301 cttgaagctg ttcatcttct actacaccaa gcactcctgg aatcgctttt aattcagaga
    18361 catttacaag atcatcattg atgatcttca tacgcacacg agtcatgcag tggacaatgc
    18421 tttctacatt gcccatgccg cctgcccctt tataaatttg ttttgccagt tcttccaaag
    18481 tcagttcgtt ttttgccatg gtcttttccc cctcataagg tcccttttac aaatccgttt
    18541 gcttcagcta attttgcttg agcttcctct ttatcactat ttgtcaaaat catgacgata
    18601 gccagcttaa cattttgatc tgcttcttca aagtactttt cagctgtttc gtaatcagct
    18661 tctgtcgctt gcatgatgat tcgttttgag cgttcgatta gtttttcatt tgttggtttg
    18721 acatcgacca tcaagttatt gaatacttta cctataccaa tcatactgat agtagaaatc
    18781 atattcaaga taagtttttg tgctgttcct gacttcaatc gagtagagcc tgtcaaaaat
    18841 tctggacctg catcgacttc gattgggaaa tccgcgtgtt tactgatttc ggcttgttta
    18901 ttgcaagaaa tcgttcctgt gacagcaccg atcgattttg cgtaatctaa tccaccgatc
    18961 acatatggtg tacgaccgct agctgcgata ccaataacta tatcattttt tgtcaaattc
    19021 agcttgatta gatcttcttg ccctagctca taagaatctt cggccccttc gacagctaca
    19081 gtcattgctt cttctccacc agcaattaga cctatgacca tttccggttc tacaccgaat
    19141 gtcggtacgc attcagcagc atctaacaca cctagtcttc cacttgttcc ggctcccata
    19201 taaatcagac gtccaccttt tttaaaggac tcaatcgtgt tagcaatcac tggttcgata
    19261 cttgtcagtt ctttttcaac cgcagcggcc actttctgat cttctttgtt cattagttga
    19321 acggcttgag aaatactcat ctcatctaat ccaaaagttt cttggtttct gcgttccgtt
    19381 gttaggttct ctaaattgat tttgctcatt tttatcttcc ttcttttctt ataaattgat
    19441 agttcatacc agctttgatt tggttgatca atggtagctc ttctttgata actttagcta
    19501 ctacattcac tttttcatcc gctggcaaat catatttggt taattggatc tcacccatat
    19561 agcgcaaata cttttcgtta tctaaagtaa tagacccttt catacgcgta gctgtatttc
    19621 ttgctgggat aggcggaatc tctcgaaaac gtgcatctac gcttcgtatg acatctcttg
    19681 catcgtcttg ccgattcgta tgcttcccta atatatattc gtaaaattct tcatctacag
    19741 gttccgtatg gagcaagact gtctgttctt tttggaaaga agcaaattgc tcctgaacgt
    19801 tttctgacag acctgcatct ccgatgtaaa caatatccgt gttacttgct aatagatcta
    19861 gagcgcctgc aagaggatgg atccctcgat gttcttccaa agttggcaat ccttgatata
    19921 gtgggcctct caactctgta tctcctggta caaaaccttg gacaaggaga ccttgaattt
    19981 tgagccattg attttttttc tgataccatt ctttgtccag ccctgtttcg ggacgtggat
    20041 aataattatg ccaagcttca atctgtgaga aatcagcttc tgcttctttc aattcatcga
    20101 tatctttagg cgtgatcgtg ctagcattca aactgatttt caattgatgt gaccagtcgg
    20161 caatctgctg attggaaata tgataatcca ttcttaaacc tgttacacca attgctttca
    20221 aaggcgttag atcttctaat gaaaaacccg ctcgttccaa tgcctctcct gaaatatcga
    20281 ccatcaattc tagtttattc tttttcgctt cgcttcctag ttcgatcaat cgcttttgat
    20341 atgccgaaac atcatcttct ggtatatgca tggaagtgaa aataccgaca aagccattgg
    20401 atgccatttg gcggatatac tgtttcttct cttctgacaa agaatcgttc ataaatattg
    20461 aaaagccaaa catattatcc ctctttttct gtatccgtct tcatttctat gactagagta
    20521 tatatctaaa gaaacaaaat ttcaatactt ttattaaaat aattaaattt catttctaaa
    20581 ggttgagttt atattatcaa aagaattgtc ataacctaaa aaaggcactg ctaagcaaaa
    20641 gcagtgcctt gaaatatttt atttaaataa cacaaaaaca taattactca taagaaacca
    20701 attctgtatt atctaccatg aatgtaaaga acccctcatt aggcatcgga tgaaaataag
    20761 cattgatcac tcttatcaag gcattatggc aaactaacag atagacattt tcttcgtctt
    20821 cgatgcattc tttcaataaa ggaacgatcc gtgcatacac atctaagact gactccccat
    20881 ttgggaatcg tacagcgaac gctaaacgtg ctttttgaaa gttctcatct ttgcttggca
    20941 gtccatcata atccccaaaa tccatttcta ccaatcgttc atcaacggtc agcggcaagc
    21001 tgagacgatc agcaactgct tgtgctgtat ctcttgctcg ttgaagaggg gaatggatga
    21061 ttttcgtgat tggaacaggc aaatctacta ccttttctgc tagtttctgt gcctgcatct
    21121 gtcctttttc agtcagcggc acatctgccc gtccgcaaac taatccttgt gcgttccaag
    21181 ttgtttctcc gtgtctcgtt acataaagca tgtgattctc tccttcgttg gcaaagttcc
    21241 ccttaaccat accttgttgt tcttgagatt acaagggtta gattctctca agagaaataa
    21301 tctcagtaga tactttatcc aggaaggttt gatcatgttc cactagtaac atggcaggtt
    21361 tcacgttcaa gatcagttgt tctaattgtt cttgattgaa gacatccaaa taattcaatg
    21421 gttcatccca tgtatatagt tcagctggct gtgataaaga tttagccaat tccacttttt
    21481 tccgttggcc catactcatc tgctcgatct tgttatgaaa aacatctctt tccatcccaa
    21541 gctttcggag gttgttcaaa aatgcttggt agtctacttg gtttttctct gcaaattccg
    21601 ccaacgttcc tcgattgtct tcataatttt ggcttgcata actaatgctc agatgttttg
    21661 gctggtattt ttctcctata accttgccgt tgaatgcccc cagaagataa tggataatgg
    21721 atgactttcc tgcaccgtta ggacctgaaa tcgccacccg ctgatgaggc tcgattgtaa
    21781 aatgaattgg ctcgaataac agattttcat accctaattg aagatcttct acgcttaaaa
    21841 gtcgcttatg gtgagacgct tggctattca tcgtcaaaga atcgatatat tcgatatctt
    21901 ttaatagttt ttctttctcg ctgatctggg tctccatccg attcacgatt gctttggatc
    21961 gtttcatcgt ccgtgcagca tcagcaccca ctgctccttt attcactcgt ctagattcag
    22021 tatcgatgaa tccgacttgt ttctttgttt tatctccttc tcgggaacga gaccattcgg
    22081 ctttttcagc tgctgttttc tttagcctac tgacttcttt tttcaatttt tcattttgag
    22141 ccatttcaaa ttcatcacga agttttttct gttcttcata gatagagaaa ttcccttgat
    22201 aaagttccag ttgacttttt tcgattgcta aaacatggtc cactacttca tcgataaatc
    22261 cccggtcatg gctgaccacg atgaagcctt gttttttctt tttcaaataa gccgctactt
    22321 gttttctacc agagatatcc aaatgattcg ttggttcatc gattaacggg aaatgagtgt
    22381 catccacaaa taaaagtgcc agtaggactt ttgtcttctc tccccccgat agtgtgctga
    22441 attctctcca taagatttca ggatctgttt gcatcaattg gagctctctt tcgatttccc
    22501 atatctcaaa atccgtaata tcatttaaca cgtaataggt taaacgttct ttatcttttg
    22561 tctgttgcgg gaaataggca aattcttgct gatggattac ttgcccttga taaggtagtt
    22621 tgttttgtag aatattcagt aaagttgtct ttcctcgacc gtttcgtccg ataagtccta
    22681 gtttccattg tgtgtcaaaa tttagatttg cttgttcaaa taataatgtg ccttggctgt
    22741 cgtagccgaa tgtcagattt tttatttcga ttttagacat tttccatcac ctcgtaaaaa
    22801 aagaccagtc ctattttcag aactggctaa agaggatgca agggttggat acacacaaaa
    22861 agacccatac atcgaaaaaa ccaagccaat cccgaaaatc tgcacactgc ttccttgtct
    22921 ccacaaggta cagtctgaat gcagctttca tcaatcgact taatttttca atgcacggat
    22981 ccctcacttt gtcctatatt tgaaattacg atagcataaa gaaaatgatt ttgtcaacta
    23041 cttcgggagg atggtgaaaa atctgctaag tgtctgtcct aagatttttg ttttttctaa
    23101 tgtttgcctg tgttccattg cttcttctaa acctattgga cccaaatgaa tacttaagac
    23161 aattgggaga aaatcagaaa gtccttctag ctcttggtct ctacttccgc aaatagcgat
    23221 tattggtttt cgatattttt ttgcaagcac tgctacaccg tatggaactt ttccgtggat
    23281 cgtttgctga tcgatccgcc cttctcctgt aatgatgaca tctgcttgtt cgatcttttt
    23341 ttccaatcca gtgatttggc tgactaaatc gaaaccagaa accatcttcg ctcccaacaa
    23401 aaaaagggct ccaccaatac cgcctgctgc tccacttcct ggaatatcat ctaaatccac
    23461 ctcccagaaa tcttttattt gctgagcaat ctttcctgct tgtttatcta agaaagctag
    23521 cgtcgtatct attcctcctt tttgtcttcc aaattgccaa gcagctcctt gttgacctgt
    23581 atatggattg gtaacatctg cagcgataat caattttact ttagaaacaa gaacgtttct
    23641 tcgatcaaaa tgaagttttt tagtagataa taaaggattt ccttctgtgt acccttctaa
    23701 agaagcaccc aaggattgga gtaatcctag accaccatcg ctacacccgc ttcctcctaa
    23761 agtgacaata atttgttcta cttcttgaag cagtgcatct ttaataagtt ctcctaaggc
    23821 ataactggaa gcaagtcgga tagtttgatc cgttggttta tcaagtagat ctaaccccaa
    23881 tgcttgtgca gattcgatga ctgcggtgtt ttttccttgc caagttgtca ataaatagct
    23941 gatttttcgc tgacggaata agagatccat cccatcaatg gtacgccatg ttcccctgag
    24001 cgcgtaatag attgcttctg cagtattttc tccgccatct gcaatcggca cattgatttt
    24061 tcttccttta cgatcttccc agccatttag aactgcctga tttagttcaa atgaagaagc
    24121 acttccttta aatgaatcaa ttgccgccaa aatatccatc tgtatccctc actttcttct
    24181 taagtaagac actttttttc atttttttca aacaaaacaa tgctattttc ttccattttt
    24241 ctatatacta aaagggaact cattgaataa aggagagaaa aaacatgaaa atcgcaatag
    24301 ctggggccgg agcaatgggc agccgaatcg gattgatgct acatcaaagc ggaaatgagg
    24361 tcctcttgat cgatcgttgg cctgctcaca ttgaagccat tcgtacaaat gggttgattg
    24421 ctgactttaa cggtaaagaa gtggtcgcaa aactgccaat ctattcacca gaagaaatca
    24481 tcgaaagcaa cgaacacgtg gacttgatcg tagcattaac aaaagccaat caattagatg
    24541 atatgttttg ttcgatccaa tccattatta ctgacaatac ttatgttttg tgtttactaa
    24601 atggattagg tcatgaagat gtactggaaa aatatgtgcc aaagaaaaat atcttatttg
    24661 ggatcacgat gtggacagct ggtctagctg gtcccggaaa agtcacattg ttaggtgatg
    24721 gagaaatcga actagagaac ttggaaccag aaggcgaagc atttacaaaa aaagttgtag
    24781 aagtctttca agaagcaaat ttaaatccga tctatagcca taacgttcgt tattccattt
    24841 ggcgaaaagc ttgtgtaaat ggaacattga atggtttatg cacgattttg gattgtaata
    24901 ttgctgaact aggcgcgcaa aaagcggcag agagcatggt tcgaacaatc gtatctgaat
    24961 ttgcttctat cgcagcaaaa gaaggaatca tactagatca agaagaagtg taccaacata
    25021 ttgcttctac ttatgatcct gacaacatcg ggttgcatta cccatctatg taccaagacc
    25081 tgatcaaaaa ccatcgtttg actgaaatcg actacatcaa tggtgccatt tggcgaaaag
    25141 gacaaaaata tgatattgct acaccatatt gtgccttttt gacccaatta gtccatgcaa
    25201 aagaaggaat ccttggcgca gaataaaagg ctctctgatg agaatcagct gaatcagcag
    25261 ctggttctct ttttttaagc ccaataaaag atcaaaaaga aaacacaact ctcatgatgc
    25321 cataagaatt gtgcttgttt gtttcagtac ataatctctt caaaatgtag gttttttatt
    25381 tgttttcaac agaggagagg tcatattcgt attgctcata aatagtggaa tcgttagtga
    25441 taaatcgttt tgcccaattt tctgcatcat aaaattccaa tagctctgat aggattggct
    25501 taaatggtgt atgcagaaat tccggtaatt catctaaatc acgttctcga agcaaaaaaa
    25561 tattttcagg acgataaaaa tgataatgag caatcgcttg attatccgtc actagtttct
    25621 tttgaaaata catggattca aatgtccgca aagtcactcc ttgctgaccc tcccgcaaca
    25681 gttccagaat cccgcgcgat tcccctgttt ttttcaggta ctcttcataa gtaagatatc
    25741 caggttgttc attccctcga tgtggaagaa tgaaatagtt ggtcgtaaca tctcttttta
    25801 taaattcctg cttatagctt tctgctcgtt cttttctccc attattcgtt gcaccaaaaa
    25861 atagatccgt ctttggttcg ctagaagaaa aattcatatg tttcgaataa aatgaactat
    25921 tatgtttcag cccaagttct tttgcttcca aaaaatcaaa atgataaatc tcatcgattg
    25981 ccggttcatc ttgtgcctgc ttcagcatcg cctcgtgttc tgctttgaag tgattccaaa
    26041 aaaataacac aatttttgca ttggtaaatg ggcgcacgcg tcgagccatc tccatatcaa
    26101 atccataatc taaaaaaacg atcagctgat aatttgccaa ctgttgtcta gctgatttaa
    26161 tgaattccga ctgtagtaaa tcttttccgg accaaacatc taaagagcgg atggaaggca
    26221 aaaaataaag tgatttattt tttgcaacta gcagtacgtc atttttgttc atcttttccg
    26281 cctcactttc tctgtcactt tttcctatga tagcctgttt aaatagtaaa aagccagtaa
    26341 aacgtttcct atatttgtat gaaaatttaa catttgtatg aaaatatgat gaaataaatc
    26401 attcttctat taaaattcgc ctaaaagttt tctgaatagt tgtaattgtc tgaaaatttg
    26461 ttatcattag tcattgttaa atattgctat ttattcttaa tataaatttt gattgtgaat
    26521 ttaaaagaaa gaggtcattt atggaagata aaaaattgaa aaaacaactt agctccagac
    26581 atatcaccat gttagcttta ggtggagcaa tcggtgcagg tctatttaaa ggaagtggcg
    26641 aagcgattgg gatcgccggc ccttctgtat tgattgcttt tttgattggt gggctgattt
    26701 tatatatcgt gatgaaaggt ctgggaaaaa tcgttttaag cggtggcgac acgcatcacg
    26761 gattatctgg tttgatacgc ccttatctag gtgctcattc tgctgatttt actgattggg
    26821 tctactggtc tatgtggatt atcaatatca tcgctgaagc tgttgcagct gcttcctttt
    26881 tgcagttgtg gttcccgcac attccagcct gggtatttgt ttttatgttg gctgttttaa
    26941 ctacgatcat caatctttat tcggtacggt tattcgcaga aacagaatat tggctggctt
    27001 ttgctaaaat cagtgtcatt atcttactga tcatttttgc tacttatctt gtcggtcagc
    27061 aaatgttggg cacaggcgtt ttccctaccc ttcagcaatt gactgaccat ggtgggttta
    27121 ctcctcatgg tatgaaggga atcatcagtt ctttgcttgt agttatctat tcttacggcg
    27181 gttctgaact gattgctatc acggtaagcg aagcagatga tcctaaacgt gcgattccta
    27241 aagcaatcaa aggtgtcatg ggaagaatca tttcctttta catcattcct ttgtttttgc
    27301 ttttgattct ttttccttgg aatactttag caggcacgaa tgtcagtcct tttgtgatgg
    27361 tatttgaaaa aatgaatatc ccatttgcag cggatatcgt caattttgtg attgtccttg
    27421 ctttgttctc atctatcaat tcgggtgtgt atgcatcttc aagaattttg ttcttccgtt
    27481 tgaaggatcg aaaaggttcc tctagaaaac tagctgtttt aaacaagcat caagtaccgc
    27541 aacgtgctgt tttattttgt accagtgttc tttatcttgg tgtagctctt tcttattttg
    27601 tcggtgacaa attatttggc tatctggcag gttccctttc gtatacagta ttattgatct
    27661 ggatcattat cagtgcggca tcctttgtac tggcactaag aaaaggaaca ttatgggata
    27721 aaggaatcag cttttttgca ttagctgtct taggattgat tttccttggt atcctgttca
    27781 cgaactccat tggggtaact gtattgactg gcctgcttta cctgttcatt tatttcagtt
    27841 atcaaaaaaa gaatgatgcg ttcgtattga cgaatgaatg aaatcgatag aaaattttat
    27901 tttatttatg tggaatagat ggagctattg aagaaaggag ttgtgacaaa agtcttgttg
    27961 caactccttt ttccgaataa acagtctcat gacctcttgg taaacggtgt tcaaaaaccc
    28021 tctgtgcaaa ataattgatt gttctccatg ctcatgacat gatagaagaa aggaatgaaa
    28081 aaaaggagtt tgttttaaat gaaaaagtat tggaagtttt tgttgatgat cggtgtttca
    28141 acggtagtta tgtttggtat gatgtacttg aatgtctatg cgctcgatca tatcttcttc
    28201 agtcgtacac gagtattcat ggcgttgatg atgggtgcag tcatggcagt catcatgctg
    28261 ttgttcatgt ggaaaatgta tgaaaacaaa aagataaatg ttatgatctt agccgctagt
    28321 cttcttgttt ttgccggttc cttgtttatg gtacgaagcc aaactactgt caacgacaca
    28381 gcttggatga aggccatgat tcctcatcat tctatcgcta tcctggcaag taaacgagct
    28441 gatttaaaag atcctgaagt aaaaaaatta gcggaagaaa tcattcaggc acaagaagaa
    28501 gagatcgaca aaatgaaaaa aatgatcaaa gaaatggaat gaccattatc cgtccaaata
    28561 aaaaaagagg atgttccaga agttatcagc ttcaagaaat aagaagaagc tacttctgga
    28621 acgccgtgaa taaggggttg tgaaaaagct gccctgcatc aagtaataag aacagccaaa
    28681 caaaaatagc ttctcctatt tttcgtttgg ttaggcttat taccgcagat gcaagctttt
    28741 gaacaccgtt tattaagagg ttgtaaaatc agcgttctga cctgagtatt agagagacaa
    28801 atggaaaaat agttcctcat attttgccat tttttgagct aataccgagg gtcagctgat
    28861 tgaacaccgt ttatcgagag gttgtgaaaa agtcgcttag tttcgcgtat taagaaaaat
    28921 tttgtgaaat ggctttccac atttttgtat aaatttggct taataccgag aaactggctt
    28981 ttgaataccg tttattcgta aaagggattg tgacaaaagt cttgtcacaa tcccttttta
    29041 tgt
//
LOCUS       DACBZK010000030        28684 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.030, whole genome shotgun sequence.
ACCESSION   DACBZK010000030 DACBZK010000000
VERSION     DACBZK010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28684
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.030"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(23..1189)
                     /locus_tag="IVD66_001401"
     CDS             complement(23..1189)
                     /locus_tag="IVD66_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP6145632.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(1201..1554)
                     /locus_tag="IVD66_001402"
     CDS             complement(1201..1554)
                     /locus_tag="IVD66_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAP6145633.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            1682..2704
                     /locus_tag="IVD66_001403"
     CDS             1682..2704
                     /locus_tag="IVD66_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HAP6145634.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            complement(3143..3577)
                     /locus_tag="IVD66_001404"
     CDS             complement(3143..3577)
                     /locus_tag="IVD66_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145635.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(3687..5546)
                     /locus_tag="IVD66_001405"
     CDS             complement(3687..5546)
                     /locus_tag="IVD66_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP6145636.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(5664..6823)
                     /locus_tag="IVD66_001406"
                     /pseudo
     CDS             complement(5664..6823)
                     /locus_tag="IVD66_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
     gene            complement(7130..8554)
                     /gene="araA"
                     /locus_tag="IVD66_001407"
     CDS             complement(7130..8554)
                     /gene="araA"
                     /locus_tag="IVD66_001407"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HAP6145637.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(8570..9268)
                     /locus_tag="IVD66_001408"
     CDS             complement(8570..9268)
                     /locus_tag="IVD66_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAP6145638.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(9225..10886)
                     /locus_tag="IVD66_001409"
     CDS             complement(9225..10886)
                     /locus_tag="IVD66_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HAP6145639.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            11104..12504
                     /locus_tag="IVD66_001410"
     CDS             11104..12504
                     /locus_tag="IVD66_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HAP6145640.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(12756..13835)
                     /locus_tag="IVD66_001411"
     CDS             complement(12756..13835)
                     /locus_tag="IVD66_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6145641.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(13921..14880)
                     /locus_tag="IVD66_001412"
     CDS             complement(13921..14880)
                     /locus_tag="IVD66_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HAP6145642.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(14892..16415)
                     /locus_tag="IVD66_001413"
     CDS             complement(14892..16415)
                     /locus_tag="IVD66_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAP6145643.1"
                     /translation="MDEEVKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHE
                     TADGDGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIE
                     PNSFGLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQ
                     KKPFGVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPR
                     LPSYPEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFD
                     RQIEEIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMED
                     TLLFGSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAK
                     GQVLKQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLL
                     DQGEHYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(16425..16988)
                     /locus_tag="IVD66_001414"
     CDS             complement(16425..16988)
                     /locus_tag="IVD66_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAP6145644.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(16994..17857)
                     /locus_tag="IVD66_001415"
     CDS             complement(16994..17857)
                     /locus_tag="IVD66_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6145645.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(17871..18767)
                     /locus_tag="IVD66_001416"
     CDS             complement(17871..18767)
                     /locus_tag="IVD66_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6145646.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(18942..20213)
                     /locus_tag="IVD66_001417"
     CDS             complement(18942..20213)
                     /locus_tag="IVD66_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6145647.1"
                     /translation="MKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTLTFWNGF
                     TASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFIALNYPD
                     FAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMYMYWNND
                     LFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLANGGKLV
                     NDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIEINGPWL
                     NNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFLKYWNTT
                     EIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQISAINNDI
                     INPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(20203..21720)
                     /locus_tag="IVD66_001418"
     CDS             complement(20203..21720)
                     /locus_tag="IVD66_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAP6145648.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            21918..22808
                     /locus_tag="IVD66_001419"
     CDS             21918..22808
                     /locus_tag="IVD66_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HAP6145649.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(22881..23705)
                     /gene="nadE"
                     /locus_tag="IVD66_001420"
     CDS             complement(22881..23705)
                     /gene="nadE"
                     /locus_tag="IVD66_001420"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HAP6145650.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(23717..25189)
                     /locus_tag="IVD66_001421"
     CDS             complement(23717..25189)
                     /locus_tag="IVD66_001421"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HAP6145651.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(25826..26188)
                     /locus_tag="IVD66_001422"
     CDS             complement(25826..26188)
                     /locus_tag="IVD66_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAP6145652.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            26411..27163
                     /locus_tag="IVD66_001423"
     CDS             26411..27163
                     /locus_tag="IVD66_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP6145653.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(27303..28226)
                     /locus_tag="IVD66_001424"
     CDS             complement(27303..28226)
                     /locus_tag="IVD66_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP6145654.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(28241..28513)
                     /locus_tag="IVD66_001425"
     CDS             complement(28241..28513)
                     /locus_tag="IVD66_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145655.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT         8478 a         5986 c         4883 g         9337 t
ORIGIN      
        1 ttttcccatc tgtctctttt tgttattctt tctgcttttt caacggattt tcttcataaa
       61 gagaagagat tgttgtgtac cattcaaaaa catgagtaat cactacttta gctgctgcat
      121 aaacaggaat ccccaagatc acaccgatga ttccgaacaa tttcccagaa gtcagcagaa
      181 ctaataaaat cgttactgga tggattgcta actgattccc tagtactaat ggagagatca
      241 agcgtccttc tattgtctgc tctactgcaa aaacgatcag tactttgatg atcatgaatg
      301 gacctgctac aatggctaaa aagatagccg gaatcatcgc taaaaatgat cctaagtaag
      361 ggatcaggtt taaaaaaccc gcaataatcc ccaacgtgac agcatactct aaaccaatga
      421 ccgcaaaacc aatcataaac atgattgcca cagcaaaagc cacagttagt tgtcctctta
      481 tataagaaga aacttgacta ttcatttcac tcagcacatt caacgtcggt ttttgcatgc
      541 gtgtcggtaa aaatttgaca aaataaggtg ctaattgttt accgtctttc aatagataaa
      601 ataagataaa cggcatcgtc agcagagcca ctaaaatagt cgctaccgcg ccgacaaaac
      661 ttccaagact ctgaactgta ctcttagata tatcttggat catatcgcct gccgaattca
      721 tgaacttatc acctgctgtt tccaactgtt cgcgaaattg gttgaacagc gggtcccgca
      781 aaatctcggt taatttatta tcaatcgtat ctacatattg agggaagtta ctgatgaagc
      841 tcactgtttg ttcctgaatc ttagggatga tcactacgct cccccatgcg attagtgcaa
      901 caaccaaaac aaacagccca atgatactgt aaagccttgg tacttttcgc ttttcaaagt
      961 aatcaactac cggattcatc aagtaataca agattcctgc taaaatgata ggcagaccta
     1021 cgattgctaa aaattgccag attggtgcaa acaaatatga aacttttgta aataaaaaga
     1081 cgatcagcaa tattaacaat acaacaagta aggctgtgac tacttgatta tttaaaaacc
     1141 agcgccaaaa ccacgatacc ggtctgttct tcttattttt tccttccata attcctcctg
     1201 ttagttataa aaaatttggc ttcccaaacc aatagcaggc agtctatgcg gatgaagata
     1261 gattccattt gcaatttgtc cttcttctgg acaagcatca aaaatcaatg atacgtgagc
     1321 tactgtcttt aaattcccat tggccatcgg accgacataa tcgatcgtat atacctgatc
     1381 atcaaaagca attgttccgc ctgctttcaa agaaaaaggt tcgtcttttg atacttcttg
     1441 aatcaccgaa tattttcgta aggcagctgt tgctgtttta tcgaacaaaa tcagcatggg
     1501 ttcttccttg tttattgctt ctgtcccaat ttctgtaatc tttgcctgaa tcattgcact
     1561 ctctccttta attgctttca aaaacagtat aacacattct cattctttag ccgtgtggaa
     1621 taattatgtg atagaataaa aacgaaaact atttcattac aattaggagg aatcagctca
     1681 tatgatcgaa aagataattt taggaaccta tacgcgtcgc gaaagtaaag gaatctatac
     1741 gatcgacctt gatacagaaa aagaagaatt agccaacctt tcattagctg ttgaagaaaa
     1801 tagccctacc tatgtagcaa aaagtaaagc tggcaatctt tacacagtta ctagtgtgga
     1861 tggattaggt ggtgccggtg cgtacgataa ggattttcat tttttgaatg cggtaacaga
     1921 gtctggcgct cctttgtgtt atgtagcggt tgatgaagca cgtcaattac tatacggggc
     1981 gaactatcat aaaggtgaag taaatgtcta ccatatatta ggagatggcg aactgaaagc
     2041 agcagattca atattccatc aagaagcgac aggtcctcat aaaaaccaag atcatgcgca
     2101 tgtccactat acggatctga ctcctgacca acgattagtc gtatgtgatc ttggtacaga
     2161 tcgtgtgtat acttatgatg tgtccgaaaa cggcaaattg aatcttgtaa ctaccttcac
     2221 tgcagagcca ggaacaggcc ctcgccatct tgtctttcat ccaaatggac aattcgctta
     2281 tttatttggt gaattagaca gcacagtccg cgtgctttct tataataaag aaacaggtgc
     2341 ttttgaagaa ttacagaaaa tatcgacctt gccagaagaa ttcgacggtg aaaatggagg
     2401 ggcagctatc cgcatttcaa atgatggcaa gttcctttat gcttctaacc gaggacataa
     2461 ctcgattgct gtattcgcag tttttgaaga tggttcccac attcaaaaca agcaaatcat
     2521 ctcaacagaa ggggattttc cccgcgattt cgcactagat ccaagcaata attttgtcgt
     2581 gtgtgccaat cagaacaccg ataatctgac attatatcgc cgtcatcctg aaacaggatt
     2641 actggaatta ctgaaaaaag atgtctatgt accagaatgt gtctgtgttt attttgatcg
     2701 ttagtaagaa aaggagaatg aaatgaatca gcaagacgta ttagacagac tacgggaaga
     2761 actaaatatt cctttctttg atgggaaaat cgaagataaa gagtatagcg aagaggaata
     2821 tcagaaactc aaagccgatt tacagaacta ctttgaacaa tatgtacaga atgtagaaaa
     2881 ctaatcagct ttccatacta tctgaaaaga acatcaggac aagacttttc cgtctatcct
     2941 gatgttcttt tctacaaata aaaaaccgcc gagatggtta gactcgacgg aaaaggagta
     3001 tttactcgat tttgagtaag tacaaggttg ttgttggtta taggtatgtc attatcataa
     3061 aggattttga tcactctatc ataaaggtaa tattacattt atattagata actctagttt
     3121 ttattgttat caaagatttc ttttattttt tcaacaacaa attagtcatt ttttggatgg
     3181 cagctgtcaa ttggtctgtc gcttggtctt gttttgcttc agatgtattg aatagatctt
     3241 catctacccc tgattcaaga tcgatacttt ggatcatttc ttcacagcct gctacatatg
     3301 aaagataagc tttttcaaaa tttttatgaa tgcccattgc ttttgctggt ggacgcaaag
     3361 tactgacttt cataagcatt gcccgatatt tttttgttcc ttcttcaaat aacaggatga
     3421 tctcttcaag agtcgatttg tccagttcac ttgtttttcc ttcatcaatt gcgtttctga
     3481 tcacttcata tttcggatgc attccttctc cgattgcttc tgtttccttg acgatttgat
     3541 cgatggactg cacataatag ccaatattcg gtaacatgtt cgttttccta ctttctccat
     3601 tgttgttatt atttattcta cttgttttta tcctcaaatg acaagtactt gaaaaaattt
     3661 aatggtttct atacagctcg ccattcttat tcgtgctcaa agaaaccatc tgctaaacta
     3721 tattgtttcc ctgcgacaat gtcatattgg atcaattgat attcgtcgta aatctcttgt
     3781 tgcgagcgat tgaattgcgc ttctttatac cactgtccgt tttgatagta cagttctcgt
     3841 tcaaacgccg gaagttcctg ttctaatgat aaaagcagct gataaaagcc atttgttgtc
     3901 tgattcgtct gttccattag attcgctgca aaataaaacg gactggtgat tgcatcgtga
     3961 gtcgtttgct tttctaattc tcctttactg tcgaacataa gaaattgtgt ttcatgcaat
     4021 gtttgtttgt cattttttgc ttggatcgta tctgaataga tccctggaag atgatccccc
     4081 caaaaaacaa ctaaagtcct tctagaaaga ttcttcaatt cttccgtgaa ctgcttcagt
     4141 gccgtgctgc tataggaaat atcttgcaga taattctcta agtcaagtgt cccacttcca
     4201 tctgaagttt ttgcaggata gtctagatta tcatactttc catcgtaggg catatgtgtc
     4261 tgcatcgtga ctaaatgaat gaactgaggt gttttttctt ccttgagaag tgtcattact
     4321 tctttgtaag ctgactcatc agaaatatat ggattattct ctatcgtatc cgtataggtc
     4381 atcgtacgct cgctgatgaa ctggtcaaat cctaatgtct gataaacatc ctctctttta
     4441 tacatcgaag tattgtatgg atggatcgct gtcgtctggt atgattgtgc gtttaacgct
     4501 gaaacgatag aaggaagctg atccattttt ggtacaagca tcgtgtaagg ggtggtgagt
     4561 tgcgcattaa ataacgccat agaaaaacca gtcaatgctt caaattcgat atttgctgtt
     4621 ccaccgccat agttttgaga aagcatattg ccactatatg tttgatcagc tacttcataa
     4681 taatctgcca atggctcacc agatacttct acgccgttta atcgactagg atctgagaaa
     4741 ctttcactca tcacgaacac gatgttcggc gactcttcct ctacagtttt atttttttca
     4801 tcggctagct tctggtattt ttcagtgatt tctttgatct tttctttcga atatccttca
     4861 ggttcatcca ttggttctac cttcagattg tacaaaaacc caccgataaa accagtgtta
     4921 tagtagttca ttttctggct gtaaggtatc catagtgccg ttttattata tgcttttcgc
     4981 aacaaattat cgggattgtt gaaattactg atatacccta gcagtccaat tgccacaagc
     5041 agtgtcgtta atcggatcaa ttggaatcgc cttccttttt tcaggcttcg aaacatgtac
     5101 cagcaaaaca atcctatcac ggttcctgcg gcagctaaga tcactgtaaa cagcatagtg
     5161 ccggtcatat ctttcagcaa tccgatttca gtgatcatct tcaaatcgtc tggataaatc
     5221 ggttcttgcc gataactcat tttcatataa tttgcaaaac ctaatacacc gatggctacg
     5281 acatacgtaa gggaacctaa agggacagat cctgctagtg caatcagaaa aataagaata
     5341 atcagcaaga cgagacaggc taagaagaat ttttccgtat gccaagaaaa agcaaatttc
     5401 aacgcaaggt ctacggatag atcattttga caccactgca aaaataaatt actaaaaaca
     5461 acaagaaaaa agatactgat gattgctgct gttcctttta aaatcttttt ctgtttggtc
     5521 gaaagtctgc ttatatatct tttcaaatgc ttgctccttc atttctatca ataaaagaat
     5581 gttgcttctc ttattttagt tgtacgaaat tcgaaagtaa agaacggaaa gaagaattaa
     5641 tgaaatccaa atattctctt tctttatggc ctttctggtt tctttaataa gcggaccttt
     5701 cgtactccag aaattttttc tagctgttgt ttcacttgat tgagctgttc aaaatcagta
     5761 ctgtctatgt caatcaatat gtagacatgc tcattcttat ggttacgcga tatatctgcg
     5821 atcgctagct cgttctcatt cagcagagaa aatatctctg ctaatatatt ggttttcttt
     5881 tgataaaata tagtgaatcg aaacggcgct tggaaaaaca ttcgtgcgga tggataattg
     5941 accgcttctc taaccgtacc gaacaaaaga taatctttta aggcttcaac tgccaaacgt
     6001 ccgctgtctg ccaaagcttc ctgagtcgat cccctagatg aggcaacata agtatacggt
     6061 cattttctaa gaactcttct tctggaaaat cagtcaagta tttagccaga tgttgttttt
     6121 ccaatgcttg cataacagca tatttatcaa caatttcact tcttcctaca ttgataagta
     6181 cagcatcttt tttcattttt tctatattcg cctgatcgat caatcctttt gtatcttctg
     6241 tcaacggcag catgactacg atgtaatccg aggtagaaag aactgtttct aaatctgctt
     6301 gccgaacata atccaactgg gcatcgcgga tagaataacc caagacatcc atccctaagc
     6361 tatagcaact tagcgctact tttgtgccta tcgctccaag accaagaaga ccgatggttt
     6421 tgccttgcaa ttctcgtccc acataagcac ttcttttgtt ttctgcctgt tctaaaatat
     6481 taggacctgt tagtgtttgt accatacgac ttgcttcgat tatcggacgg gaagataaga
     6541 gcaaacagca caaaacaagc tcttttactg cattagcatt tacacctggt gtattcatga
     6601 cgatcgtccc gttttcagaa gctttttcaa cgttgatcgt gttcacccca acaccagctc
     6661 ttgaaattgc tagcaaatct ggtgtaagcc attcatcttt cactttcgta ctacgaataa
     6721 ctattccttc ggctggcaaa tcatctatta ttttgaaata ttccccttgt aacttttcta
     6781 tctcttgttc tggaatagca tcaatcaaat gaacgtgata cataaaaccc cctccttact
     6841 aacaagtatc tcgaaatttc tgcaattaga caactgttta ccatttgact tcctagaagc
     6901 aaaaagagca gttagagcag agtaggctga gtgataaaaa taaggctatg acaagttact
     6961 gccataagcc ttattttcga gagcaaaata ttgagggtga gatatcttga taaatggtgt
     7021 tccgttagct gacattgata ataagactaa atttcaaaaa agttgaaaag caaatttcgt
     7081 caatctcttc ttatttctta aaactaagtg gctttttcac aacctctttt tatctaataa
     7141 ccactgtttc caactcaact aattttgccc acgtttcaat ttgatctgtt gttagattta
     7201 gcgagacaac ggtatgatga ccgccacctg cctgaatcca tgaatggaca ccttcatgga
     7261 aattcggttt agttttccat aacacacgtg caacaggtaa attaggtgct tcagtcgttg
     7321 gttcaaaggc ttctacttca ttgatcagca gtttataatg cgtaccgaaa tctgccatcg
     7381 atacgactac cccttctcct gctttcccat caaatacaag acgcgccgga tcttctctat
     7441 ctcccattga taaaggagaa acaacgattc ttggtttcgt cgcagcaagc gtcggatcta
     7501 cttccatcat atgggattcc aagattgctt cttggccact agctagctcg taagtataat
     7561 cttccatgaa tcctgtatct ttccctcgag ccatgatttt cagcaaccga tcaatcgctg
     7621 cagttttcca gtcgccttcc ccagcaaaac cgtatccttc tgccatcaaa cgttgtacag
     7681 ctagtccagg tagttgtttc attccataca ggtcttcaaa attagtcgta aaagcgttat
     7741 agcctccttc ttctaagaaa cggcgaatac cgatttcctg ctgagcttgt acttttacat
     7801 gttcctccca tgtcttttct tcataatcac catagtcgaa ggtatacaat tccttgtact
     7861 cttcaaataa ttgatcgact tcttcgtctg atacgcgatc gattacttgt acaagatctc
     7921 cgataccaaa ataatcaaca gtccaaccaa attgaatctg tgcttccact ttgtctcctt
     7981 ctgtgacacc cacgtttctc atgttgtcac caaaacgagc cacttttatt ccaaaacttt
     8041 cattataggc tactgcaaca tccatccaat cagcaatctc tttttggatc tcaggtcgtt
     8101 tccagtagcc aacgacgatt ttattttgtt tatttaatcg agcattgatg aacccatatt
     8161 cgcggtcacc atgagcggat tgatttaaat tcatgaaatc catatcgatc gttttccaag
     8221 gaatgctttc gttatattgc gtagctaaat gaagcaatgg tttttgtaga agctttgtcc
     8281 cgcggatcca catttttgct ggtgagaaag tatgcatcca agtgatcaca cctgctactt
     8341 cttctcgata attgacctct ttcatgattt ttgtgatcgt atcagcagta actgctaatt
     8401 cttgaaggcg gattggataa ggcaattggc cattttcatt cagttcatcg accatttctt
     8461 gtgcatgttt ctttacttct cgcagtgctt cttccccata taaatgctgt gatcctacaa
     8521 caaaccaaaa ttctttttct ccaatattca acataattag ccactccttt tatttgtttt
     8581 gtccgtaata cgcatttttt ccgtgttttc gtaaataatg tttatctaaa atccgttgag
     8641 gcagctcttc tgaaaatgaa ttgagctgtc tggtaaataa attcatcttg catacttcat
     8701 ctagtacgac tgcgttcatt accgcacttt gcgcatcttt cccccaagta aatggaccgt
     8761 gtccgtgtaa aagtacccct ggaattgcta agggatcaat tttgcgttct ttgaatgttt
     8821 ctatgataac ttttcctgtt tcatattcgt acccgctgtc gatttcctgt tgtgtcaaaa
     8881 atcgagcaca aggtaccgat ccataaaaag tatctgcatg cgtcgtcccc atcgcaggaa
     8941 catccaatcc tgcttgtgcc cagatcgtcg cccatgtcga gtgagtatgg acgattcctc
     9001 cgatttgagg aaatgaacga tataaaacag catgagtagg cgtatccgaa gagggattga
     9061 gtttaccttc aatgatatga ttgtccaagt ccacaacgac catgtcgtct gctgtcatct
     9121 cttcataact gactccgcta ggtttgataa cgaaatatcg tgtttcagga tcaaaagcgc
     9181 tcacatttcc ccatgtatat ttgacgagtc cgtgtttagg caagtcaaga tttgcttggt
     9241 atacttcttc tttcagttgt tccagcattt tctatcactc ctttttcttg caattgatga
     9301 atcgctgttt tttcaatgtc gatcccctca cggtaacgtc tcataaatat ctgatagcct
     9361 gctatttctt ctgctgaagg tgtgatggtg attccttggt cttgtccaaa cacgtcttct
     9421 gccaagaagt tttctaaaga cttcccatgt cgatccatca tataggctgc taataacgcg
     9481 attccccacg ctccaccttc tccggctgtg tccatcactg taactggtgc ctccatagca
     9541 gatgctagaa tccgctgtcc aacttctggt gttttaaaaa tccccccatg ccccactaaa
     9601 cgatcaattt ggacattctc agatttcaat atatccattc cgattctcat tgcaccaaaa
     9661 gcactggcta aatggatccg catgaaattc gctaaatcaa aacggctacc tggtgtacgt
     9721 acaaataatg gccttccttc atttactcct gtaatgtttt caccggaaaa ataaccataa
     9781 gaaagtaatc ccccgcaatc cgtatcgcct tctagcgctt tgttgaataa taccgtgaat
     9841 aatttatctc tgcttatctc catacccaaa gaattggtaa attcttcaaa aatactgacc
     9901 caagcattga tatccgaaga gcagttattc gtatgaacca tgcctactag ttctcctgaa
     9961 ggtgtagtga ccatgtcgat ttccggatgg acattttcta gttctttttc taatacgatc
    10021 atagcgaagg cggaagtacc agccgaaatg ttccctgtcc ctttggctac actgttcgta
    10081 gcgaccatac cggttcctgc atccccttct ggcggacaaa ccgggattcc tggtctcaaa
    10141 tttcccgtag ggtcgatcag ataagcccct gattcgctta acttgccagc ttcttctcct
    10201 gctactagaa ctttaggcaa aatgtgatcc aagtcaatcg ctacgtgcgc tttttcgatt
    10261 aactgaccaa aaatattttt catttcttga tggtaggttt tcgttgaagg atcgatagga
    10321 aacatgcctg atgcatctcc tacgcctagt actttctcac cagtaagctg ccaatggaca
    10381 taacctgcaa gcgttgtcaa aaaattaatt tctttcacat gttcttcttt attcaaaata
    10441 gattgataca aatgagcgat actccatctc tgcggaatat tgtattgaaa tttttccgtt
    10501 aatattcgtt ctgcttcttc agtgattgta tttcgccaag tacgaaatgg tactagtaac
    10561 tgttccttgc tatcaaatgc tagataaccg tgcatcattg cactgaaccc aatcgacccg
    10621 attgtcgtaa gattctcgcc atagatttcg aatacttctg ctgccatttt tcggtaactg
    10681 acgcgcagtc ctttccaaat atcttctaat gaataggtcc agataccatt ttctagtttg
    10741 ttttcccact cataactacc agcggcaata ggagtaaaag atgaatcaat caatacagct
    10801 ttgatcctag ttgatccaaa ctcaatccct aaagatgtac gaccatctat gacatctaac
    10861 atactttgcg catttacttc cttcataatg atttaactcc ctccttctcg tcaaacctga
    10921 tcaaaccgtc tttttagtag cgcttacaat gattattgta tacttttgta cgtacatgtc
    10981 aagcagttat ttacaagaat acaataaaaa acacttgttt tgtacgtaca taagttataa
    11041 aatgaaattg cttacaaaat ctgatcaacc gccttctcga aattctagaa ggagagaata
    11101 cttatgaaaa aagaaaaaaa agtttcctca tcgtttattt atttttttgg cgcatttggc
    11161 ggcattctat ttggatatga tattggtgtt atgaccggcg ccttaccttt tttacagcat
    11221 gattggggtt tggcaggtaa agcttctttg ataggatgga tcacgtcttc ggtcatgtta
    11281 ggtgcgatcc ttggcggctc tttatctggt cttctttctg ataagcttgg acgacgaaaa
    11341 atgattcttc tttctgcact tatttttatg gctggttctg tcctttctgc atctgcccct
    11401 cacaatggtt cttattttct gattgcagca aggattcttc taggtttagc tgttggcgct
    11461 gcatctgccc tagttcctgc ttatatgtct gaaatggctc ctgctagact aaggggaaga
    11521 ttgtcaggga tcaatcaagt gatgattgct tctggcatgc tcctttccta tgttgcagat
    11581 tatttgctaa aagggttgcc tgaaacgatg gcttggcgcg tgatgttagg gctcgctgct
    11641 gtccccgcgc tgattttatt tttcggtgtt ttagctctac cagagtcacc gcgttttctt
    11701 atgcaatctg gccgcttgga agaggcaaaa agagtattga actatattcg gacaccaaaa
    11761 gaagctgaac aggaattcga acaaatccag ctgaatgtca aacaagaaaa gacaaccgga
    11821 acttcttggc atactttgtt tttagaaaaa tatcgttcct tagtcattgc cggtattggt
    11881 gtagcagtat tccagcaatt tcaaggagct aatgctattt tttactatat tccgctgatc
    11941 gtagaaaaag cgactgggca tgcagcgagc gatgcattga tgtggccgat catccaagga
    12001 atcattttag ttgctggttc tttgctcttt ttggttattg cagacaagtt caatcggcga
    12061 actttattga aaataggcgg tagcgtgatg ggactttctt tcatcctacc agctgtttta
    12121 ggaactgtac tggatgctca tacaaattcg ttgttgattc tcttgttttt atgtatttat
    12181 gtcgcatttt attcttgcac atgggctcca ctgacatggg taatcgtagg cgaaatattc
    12241 ccactagctg tccgcgggcg agcatctggc ctagcctctt cttttaattg gattggttct
    12301 ttcctagttg gcttgctttt tcctgtgatg actgcttcta tgtctcaaga aatcgttttc
    12361 ggcatttttg ggatcatctg ctttttaggg gttttattta ttcaagagat cgtaccagaa
    12421 actcgtggga aatctttaga ggaaatcgaa caaagtgcat ctaaaaaaac ttatcctaaa
    12481 cgtatttcta tccatcattc ttaaagaggt tgtgacagaa gtggtcagct tcaagaaata
    12541 agaaggaacc gcttagtttc cagtcacaag gaacaatttc aaaaaacagc ttctcatgtt
    12601 tgatgaatat tgtgacttgt gaccagttgg taggagaaca ccgtttagtg gagaggtggt
    12661 gaaagaaacg ttcagccttg agcgatgaca aaagctctca caaacattgc gacgagtaac
    12721 cgtaggagca ataagaggcg gtaaaaaccc gtctcttatt tttcgttttc tttcactgtt
    12781 tcccgttcaa ctagtacagg ttcatagaga atatttggct gtgcctgtcc tttttcaatc
    12841 gttgtgacga tccaccgtgc ggcatcttgt cccaactttt cttttggatg cgtcaatgtt
    12901 gtcaattttt tattccctaa atggcttaaa gaagaatcgt ctgttcctac gatcgatagg
    12961 tcatctggaa tatgatagcc attttctgtc aacttatcta gcattaaact agctatttga
    13021 tcgttatagc aaatgatgcc atctaaagct tgttcttctt tcaaccgttg tactgttttt
    13081 tcagcgattg tttctcgtgt ttccgtggtg aaagtaatga tatcttccgt caaaaaacgc
    13141 acattatact gttcacacgc gctgataaaa cctttcatcc tgtattttcc ttgaagatcg
    13201 tcgatttttg tgatgaacaa cagacgctga tgtccttttt ttatcaaata ttctgctgcc
    13261 ataaaaccga ctttcacatc atctaaacaa atataagagg catttaactc ttcataagca
    13321 gcattgatca tcaccatcgg aatgccttgt tctctcaaag caacataaag tgctaagttt
    13381 gggttatact gattactttt cgtaggctca acgatcaaac catctacccc ataagcaatc
    13441 attttcttca aacactcttt ctccaattcg tgatcgttat tcgtactggc taaaagcaat
    13501 gaatacccag attctcgtaa ttcattttcg attcctcgga taatcgacgg aaaaatataa
    13561 tcagagagat atgtggtgat gacaccgatc gtttttgttc tgttcaatgg tgttttttct
    13621 ttcttatagc tgtcatctac atatgtgccc gacccttttt ctttacgcag atagccctca
    13681 tttaccaaca cagcgattgc ttgccgaatc gtatgtctgc tgacgtcata tatttcttgc
    13741 agcttgaatt ctgagggaat ggttgtattt acttcgtatt cctcacgaag gatcttttgt
    13801 tttatctctt ctgcaatatc ttgatatttt gccatttgcc ttgccccttt ttatttgtac
    13861 gtacatatat cataacgagt ctgcaaggtt tattcaagca aaaatcaagg tttcttgtgc
    13921 tcataaggca tacggaacag gttcaccaaa ttctggaaat ccttgctcat tccacgtaaa
    13981 gcattgcgcg ttcgcgtgcc gattaggatt gtctaacgga tccccttttt ggttcttctc
    14041 tggtcgagca tgatagatca aaatatcaaa gcacccgtct tctgaaaccg taaacgagtt
    14101 gtgaccagga ccaaattgct tatttttttc agaagaaacg aatactggct ccgataattt
    14161 atgccatgat tcttttaata aaagattctt gtgctcatca gcccacagca ggcccatggc
    14221 atagttttca tctgttgcac taccagaata cgtaatgaat attttcccat tgcgagtaag
    14281 gactgctgga ccttcattta ctgaaaaacc ccgtttttcc cattcatact caggtataga
    14341 aaggaggatc tgcttcccct ttaacgtcca aggattatcc atttcggata gataaagatt
    14401 agaattccca gtaatttcag gatcttgttg ggcccacaca taatatagct ttccttgaga
    14461 agagaaagtt gttccgtcta aactgaaagt ttcccttttc gtttttattt gtcccttttc
    14521 tatccaatct gtattcattg gatctatatg ctgattttca agtacgaaca tgcggtgatg
    14581 atgagattca tcacgtatag ttttatgatt gcttgcagca aagtaaatat accattttcc
    14641 attgatataa tggacttcag gtgcccagat caattcactc atcggtcctt cttcatgagc
    14701 ctgccataca atcaggcttg cagcatgttc taattcattc agtgactttg cccttcttaa
    14761 ttcaatcact tggtagcctg gaaccgatcc tgtaaaataa taataaccat ctgtatgttt
    14821 atatacccaa ggatctgccc gttgccgaac gataggatta ttataaagtg tcttcatcat
    14881 aacaaatttc ctcacatttt ctttattcta attacattcc aagagtattt ttctatccct
    14941 acatttaatt cgtcatgttt ttctattgaa aaatagttta tttcaggttt tattttttct
    15001 ggttcttcac gtgtattttt gtccaacaga tcgctactgg ttaatgtgta gtgctctcct
    15061 tgatctagca aattgaaatc atgttcaatc gttatctttt gttgttcatt tgtgcgattg
    15121 atcaagaaaa tagtcagctg attgccgtta tctacgatca cactgtccac ataaggaaca
    15181 ttttttatct tttcacaatc ataaacaggg caaatgattt gttgtttcaa tacttgacct
    15241 ttagcatatt tcgataagtg ttgcatcaca taataagttg gattcctcca tgcttgtcct
    15301 ttagcatctg tcagtattaa aggtattgtg tttactaaca atgattgaca actaatcttt
    15361 acgcgatctg cgtgtcgtaa aatagccagc cctaatgaac caaataataa tgtatcttcc
    15421 atagtaaagt aacaccaatc gatgggacta ccgacttcaa aatccctatg tcttttttcc
    15481 ggttgggcat gtacattcca ttcatcaaac gctagataca ttgttttctc acttctcaaa
    15541 tatcctttta cataatcaca agtagcaacg atttcttcaa tttgacgatc gaatcgataa
    15601 gcttttgcaa ggtatgtcgc tgtatcatca cgctcatttt taggaggttt agtcaagtct
    15661 tcttcatcat acttatcaat atagttatgc aaagctaaat aatctacatt ctcataagct
    15721 tcttctaatg cgatacgatc ccattcaggg tacgatggta aacgtggcgt agagcttcca
    15781 actaagattg tttcaattga atcatccact aacttcatga cttttgaggc ttcatttgct
    15841 aacctaccat attcataagc actcttagcc cccacttgcc atggaccgtc tagctcattc
    15901 cctaaacacc ataatttaac gccaaaaggc tttttttgcc cattttttat tcttaaatca
    15961 ctccagaagg ttccttttgg aaaattacaa tattctacta aattttttgc ttcatcaatt
    16021 ccttttgttc ctaaattcac cgtgaatatc ggtttcgctt gtacatgact gatccattta
    16081 aaaaattcgt ggagtccaaa agaatttggt tctatacctc gccatgctaa atcaattttt
    16141 tttggtcgtt gttctttcct acctacagta tccacccaat cataaccaga tgtaaagttt
    16201 cctccaggat agcgaatgac acctaattct aattccttta cataagagag gacatcttgt
    16261 ctaaacccgt caccatcagc tgtttcatgg cccggttcat aaatccctgt atagacgaca
    16321 cttcccatat gctcaacaaa tgagccaaac agccgagaac tgatctctcc taccgtaaaa
    16381 tcctctctga tttttacttt cacttcttcg tccaacagct ttccctacct ttcatttcct
    16441 atagtcaaga taatagatac aagtttccat acgccaccag caaagataaa aataaaagga
    16501 gggaaaagaa atatgagcag tacaaatcct aataacaata cgcaacaaag aatatttctc
    16561 aaaaaatcaa aaaatacttt ccatgcactt tgttcaaaaa tttgtaaaaa tgtgatatct
    16621 ttgttttcag aaatcacata tatccaggat aaaagaaaca tggaataaat aagtaaaact
    16681 acatatccac taattgaaag tacgattgtc tgttcttcta ataattgatt aacaagaaaa
    16741 taaataatga tcgttaacag actaaggaac aagttcttac caaaatgttg ctttattcct
    16801 tgaaagaaaa aataaatgat atttcctgat ccctcacctt tccattgcgc cattacataa
    16861 aaaacagcac atgtagcagg cacgatagta ataacaggca aacacacgat tacccagaga
    16921 atacctaata agatgtaatc agaaaccaca atcaactgtc cataaagttt agtctcaact
    16981 attttcatct tcctcactct ttcattccag acatagctgt tccttgaaca aaatatttct
    17041 gtgcaaaaat ataaaccact agtaatggca gcattgaaat aaccgttcca gccattacag
    17101 gtccataaaa agaaatgttc tgccctgtaa ataaagctaa ccctgctggt aaagttctca
    17161 tttttgaact acttgtcaat atcaatggat aaagcaagtc attccaacta ttcatcagcg
    17221 tgaaaatccc taatgataaa agagtaggtt tgctcaatgg caacatgatt ttcaaaaaaa
    17281 tattaaactc acttaatcca tcaatgcgtg ctgcctcttc caaagaatct ggtaaagtaa
    17341 taaaaaagga acgcatcatg aagataccaa atgcagttgt catacgagga atgatcaaac
    17401 ctgcataagt atcaagcatg ccaagcaaat tgacttcaat aaatagagga atcatgaaga
    17461 cttggaatgg gatcatcatt gtcagcaaaa cgaaatagaa caaaactgat tttcctttga
    17521 aacgcatacg agcaaatgca taccccgcaa gagaatcaaa gaatacagaa gtgatcactg
    17581 tccctccagc aaaaatcact gtatttttga tgtaatctaa taaagggatc gttgtccaaa
    17641 ccttaatata gttatctagg gtatagctat ctgcaaatat tctaggcgga aatgagataa
    17701 tgtctttttc gtgtttaaaa gaagaaataa tcagccacaa aaaaggaaac gcaataacca
    17761 acaatataac tagcatacta atcgttcgaa tgattttttt accactaact gcttttcgac
    17821 tattcacagt aactgtaatc gagctttctg gtgccataca ggtttccctc ctatttcatt
    17881 tgtttttctt tccgtgacat gtacacatta gtggagatag ctatagttgc aacaatgata
    17941 aacaaaaccg aagacagtgc tgatgcatag cccaattcat aaggtgctgt aaatcctcga
    18001 ctgtaaatat attgaacagc tgtttctgtc ttaaattgtg ggccaccagc ggttgcaaca
    18061 tatacttggt caaacacttg catcgaacca atcagattcg ttaaaataca aaaacctaag
    18121 gagggaacga tctgaggtag cgtaatgtta aaaaactgct gtcgatttgt tgcaccatcc
    18181 atttgagcag attcatacaa agagggagag attccctgaa tagcagtcaa gagaatcgtc
    18241 atagtaacac caaaattctt ccaaacagtc atgatggcta ccgtcggcat agcaagggtt
    18301 ggatcgcgaa aaaattgagg gatcggcaag ccgacttgtg aaaacaagta aggaatcgcc
    18361 cctacattcg gatcaagcaa catagaaaaa ataatcgcaa ttgacgtcaa tgaacaaata
    18421 actggaatgt aaaatgtcga acgacaaaaa cgattgaatc tggtattttt agataatgct
    18481 actgctgcta ataaaccaac gataatttgt gttggcgttt cgagtacggt gaaatataaa
    18541 gaatgaatca acgaattaac tgctcgttca tcactaaata tacgtgtgaa attttcaaaa
    18601 cttacaaaat ttcttgatgt aaagaaaata ttcaaatctg taaaactaat agcaaatgtt
    18661 cctaaaagcg gtatgacagt aaataataat aaaactaaaa aagatggagt taaaaacaaa
    18721 tacgcagcac gatcaggacg attccaatat ttggtgaatc cgttcatata gtccacctca
    18781 tctttcattt tgataaaata tacaatcttg gtttaaacga atctgaataa gatatccgaa
    18841 caatcgctgt gatttttgca ataacaccta tctgcaaata ctaggtcgat cattcagata
    18901 tctgtatctt gccaacagtc tatcctgtat aaagttctgt actatttttg cagtaattga
    18961 ttgatggcat catctgcatc gttcatgagt gtctcaggat cttctcctgc taataatttt
    19021 tcaatcagtg gattgatgat atcgttattg atcgcagaga tttgggtaaa acctggtaaa
    19081 tatggctctg catagtccat ttgtttcgat aattcagata caataggatc attttttact
    19141 tcttcatctt ttgctactga atccaagtag gcaggaaaac cattttcgat actccatttt
    19201 ttaccaattt cagttgtatt ccaatatttc aaaaactcat agacagcttc ttttttatta
    19261 ttatctgtac ttgccggaat ggcatatcct acgccatcta aaatagctgt ttttttgtct
    19321 gaatcactcc cttgtggtaa ggtagtcaca ttataatcaa tctcgtttgc tttcaatccg
    19381 ttatttaacc atggcccatt gatttcaatg gctagttgac cagcattcat taaattgtcc
    19441 atttcggcgc cagaaatcga ttctggacca gtcttgtcta catggatcat tttttggatc
    19501 gcttttaacg ttttaaggtt ctcaggagac gcaaattcag acttagtata atcatcgttc
    19561 actaatttac cgccatttgc taacatccag ttatataacg gtgcagttcc atccttattg
    19621 aagacaaaac ctgatacatt tttactacta tcagttaatt ttggtgccat ttctgtcaat
    19681 tcttcccaag tagtaggtgg ttgttcagta tctaatccag cttgtttaaa caaatcatta
    19741 ttccaataca tatacatgcc ttgtacctgc atggggacaa aatactgttt accttctact
    19801 tcacctaatt caatagccgt ttctttaaaa tcagatttat ctactccatc atattcccag
    19861 aaatcgtcta atggttgtac cgctccgttt tctacatact gtgcaaaatc tggataattt
    19921 aatgcaataa agtcaggtgc ttttttagaa gaaatcgctg taggaagttt ttcattcaaa
    19981 ttggcccaag tcatgatatc catttcaatt ttgatgtttt tatcatttgt tttattaaat
    20041 tcattaacga tttcttgcaa tatttcacca tcagatgcag taaacccatt ccaaaaagtc
    20101 aaagtcactt ctttatcaga atcagattct gctgaacttc cgccaccgca agctcctaaa
    20161 atacctgttg cagctaccaa caaagagcca attaaccatt ttttaccttt cattttttgt
    20221 tcctccttca tctgataaac gacatctgac cacattccaa gatagcggtt tcaataaaca
    20281 attgattttc ccatcttcag cttttacatt tgttgaatga cttggtttta cttgttcact
    20341 tttaggaaga ttagttgctt ttgtatcaaa tccactcatt tcagaaaaat caatcactcc
    20401 ctctaatgat aattcagaca agtgaacagt tagattcatt tcttcttctc cacggttaac
    20461 tgcaaatatg acaagttctt tgtcatttat tacggctata ctttctaaat acggcacttc
    20521 ttcaaaatct tccgtcgcat agtttgctga acgaatttgt gggcttaaca cctctccttg
    20581 tccatacaca gcagcttgca taaatggata atagatcgtc tgtctccaag cttctccgtt
    20641 tgtttctgtc ctgattggtg caataacatt taccaattga gcaagacaag caatctttac
    20701 tctatctgca tgtttcaata aagtgattaa tagacagcct aatagtaatg catcttcaaa
    20761 attatagtta tcttctagta aaggaggagc aatctgccaa ggcgctgctt gctcatcttg
    20821 ttccgctgaa tgataccaaa tattccattc atcaaaggac aggttgatct gcttcttact
    20881 atgtttcttc gccttgactg tatcgcacat cgctgtcact tcagaaatga accgatccat
    20941 gtctaaggaa cgtgcaagat aatgagaaag atcatttttt tggttgccat aatattgatg
    21001 cagagacaaa taatctattt gatcgtacgc ttgatcaaga actgttaact cccaatcacc
    21061 aaatgtaggc atttgccgat tcgaacttcc gcataaaacc acctcaattg aatcatctac
    21121 gagtttcatc gccttagccg tttcctctgc taaccgtcca tattcttccg ctgttttatg
    21181 tccaatctgc caaggaccgt ccatttcatt ccctaaacac catgtcttaa ttccaaaagg
    21241 gctctcttga ccattcgaac gccttaaatc actccaataa gttcctttag gaaaattaca
    21301 atattcgact aaattacgag ctgcatctac tccacgagta cccagattga cagccatatt
    21361 gatttcggcc cccacatgct gacaccagtt ataaaattca tgaatcccaa cttcattcgt
    21421 ttcaattgtc cgccaagcta aatccaacct tctaggtcta tttgctatgg gcccaatact
    21481 gtcttcccaa cgaaatcctg acacaaaatt tccaccagga tatctaatca tgggaatgtt
    21541 caattctttt accaagtgaa tgacgtcttg gcgaaatcca cttttattag ctgatggatg
    21601 atctggctga taaatccctt catatactgc tcgtcccata tgttcaataa atgaactgta
    21661 caaccgcgga tcaactttgc ctacacgctt gacactacta atcaacattg tggcttccat
    21721 aactgacctc ctttaattta tacatgaata atacacctcg ttgaaagcgt tgtcaataat
    21781 ataaatgtta aacttactta ttttttatcg attttaatta accaaaatat taataatgat
    21841 taaaacaaat aatttaatat aacttttatt aacaaatatg ttaatatata agaaaaacct
    21901 tttaagaggt gatatatatg caactacaaa taaacgaaga atccttaccg gtatatgaag
    21961 cattagctag taaaacaagg atcaagatca tccagctact ttccaaaaaa aagatgaatg
    22021 tcaaagattt ggcaaaagaa cttggagtga gcagtgctat cacgacgatg cacgtgaaaa
    22081 agctagagga agcaaacatc atcaaaacag aaaaagtagg acaacaaaaa atttcgagcc
    22141 ttcgtgtcga taaaatcgat atcagttttc cagaaaaaat attcaatgct tttgatacga
    22201 aagaaacatc gatacctatt ggtcactata caaattatgc aattgaacca acatgcggtt
    22261 tagctacgat ccatgatttt atcgggaaag tggatgaacc acgctatttt atggatcctc
    22321 gaaggatgga tgcccgcatt ctctggttta ccagcggatt tgtcgagtat caggcaccta
    22381 attttttaaa tacagaggat acattggaga tgttggaagt ttctgtggaa atttcttctg
    22441 aatttccttt ttcaaatgac aattggcctt cagatatcac tttcagccta aatggtgtgg
    22501 agctaggaac atggacgagc cctggagatt ttgctgatat ccgcggtaaa tatacgcctg
    22561 attggtatcc agataatctt aatcaatacg gcttgctgaa gacgatccga attaccaaac
    22621 acttgacgaa tatgaatgga gaacccttgt caaacatcac gatcaacgac atccctaaag
    22681 agcaagacac ttggcatttg cgaatcgaag tgaaagacga tgccaaacat gtggggggct
    22741 gtactttatt tggtaaagga ttcggtaatt acgatcagga tatcaaatta aaagtttact
    22801 acagctgata tttttctttt ctattttata aaacaaaaac agccaatccc tatgaaggga
    22861 cggctgtttt tgctttattg ttatttccag aaatcatcca aaacggaaat tggcaaatgt
    22921 cgtttatgtt gtgtcttgtt ccaccatgct tcgatttttt cttgtgcttg agcgggaact
    22981 tcttttcctt ctagataatc atcaatttca ttatatgtga cacctagtgc gacttcatct
    23041 gcaatcattg gtttcccatc ttcaagatct gcagtcggaa tttttgtgta taatttttcc
    23101 ggtgcattca atgcttgaag caattgtttc ccttgtcgtt tgtccaaacg gaataatggc
    23161 aaaatgtcgg ctccaccatc accaaatttc gtgaagaatc cagtaatgtt ttctgcagca
    23221 tgatctgtcc ctaatacggc tcctgctctt tctccagcta cggcatattg cgtaatcata
    23281 cgttgacgtg ctttgatatt tcctttgtta aaatcgctga ttcccacacc tgcttcgctt
    23341 aatacttgta cttgtgcatc aacagctggt ttgatattta ctcgcagact aacatcgggc
    23401 tggataaagt caagagcagc ttttgcatct tcttcatctg cttgttcacc ataaggaaga
    23461 cgaacagcga taaattgata gttttcatct tttgtttctt cacgcatttc ttccatcgtt
    23521 agttgcgcca aacggcctgc taaagtagaa tcttggccgc cgctgatacc tagtacaaaa
    23581 gttttaagaa acggatattt tttcaaatat gctttcataa agtcaatact tttacgtatt
    23641 tcttcttttg gatcaattgt tggtttgaca cctaattcat tgataatttc tgtctgcagg
    23701 ctcatttatt ctcctcctat gcttctgtat gaagttctgc tacgcttttt ttcattcgtt
    23761 ccatgatagc cattttatgg ttccagcatt cagtagacag atcgactggg tatttttgcg
    23821 gattcaagtc tcgtttatac tcttcccata gtgaatctag attttctttt gtatattctt
    23881 tgatttcgtt tagtgcaggt aattcgtaaa ctctttttcc ttcgataaag atatcttgta
    23941 aaactgggcg agctgtaaag tctcgaacag ttttattgat aaacgtatgc actggatgga
    24001 acatgaagat agcttcttct tctcgagggt cttcatccca taatgtcacg tagtctcctt
    24061 cagatttccc atcaaaattt cgagtgatgc gccacacttg ttttttccct ggagtagtta
    24121 ctttttctgc attgcttgat aacttgatcg tatccatcat ttttccttca tcatcttcga
    24181 tcgatactag cttgaatact gcaccaaggg ctggctgatc ataggctgtg atcaattttg
    24241 tcccaacacc ccatacatca attttagctt tttgcatctt taaattcaaa atcgttgctt
    24301 catccaagtc attcgaagca tagatttttg cttccgtaaa tccggctgca tctaattgtt
    24361 cccgaacacg cttagatata taggccatat ctccactgtc gatgcgtacg ccttggaagt
    24421 tgattttgtc acctaattct ttcgccacgc gaatcgcact tggcacacct gatttcaacg
    24481 tatcataagt gtcgactaag aacacgcagt ctttatgggt tttagcgtag gccataaatg
    24541 cttcataatc atttccataa gattggacta acgaatgagc atgggtcccg ctagctggta
    24601 tcccaaatat cttcccagca cgtacattgc ttgttgcatc tgctccgccg atatatgccg
    24661 ctctagttcc ccagactgct gcatccagtt cttgtgcccg tctagttcca aattccaata
    24721 gtggatcttc tccgatgaca gatttgatac gagctgcttt tgtcgcgatc aacgtttgga
    24781 aattgaccat attcaacagt gctgtttcta ctaattggca gtgcgctaaa ggcccttcca
    24841 cttggattaa tggttcattt gcaaaaacta gttctccttc acgagcagaa cgaactgttg
    24901 ctttaaattc aaaattttgt aaatactcca aaaaaccttc aggatagact tctaatccac
    24961 gcaagtaagc aatatcggaa tcattgaacg tcagattctc taaataattg actaaccgtt
    25021 ccaatcctgc aaaaaccgcg tatccgtggt taaaaggcat ttctcgaaag taacattcaa
    25081 aaacagcatg taaatcagct cgacctaatt cccagtatgt ctgcatcata ttgatttgat
    25141 atagatccgt atgcagcgtc aaactgtcgt ctgggtaagt attattcatc ttgtattact
    25201 cctcttggca agttttcatt tcctacccat tataacaaaa aaaattaata ggaaaagaaa
    25261 tcttccattt tttctgaaaa agcacatgtt ttacggatat ttcttgctaa aaatgaactc
    25321 catctgctaa aactatcctt tcttattggt atttaaccta aacgagaaag aatacttatt
    25381 ttattcaatg tatccgagac acgaagaaat tagcgttttc tatttttctt acttgataaa
    25441 ataagtagat tttcctacta caatcgtagc cgttaagata ccgatgattg aacaaatata
    25501 accaaatgtc tctacaacat aatcaatggc aaaagttttt gaagcaataa tacgtctttc
    25561 cttttttgct tcttatcccc aaagaaacgg atataactta ttatgtattg aatttttttg
    25621 gaaaggcgaa ttatgacaag atataccttg cgttgaaaaa actcgcggaa aaaatatcac
    25681 acgtttttaa aaagatacaa agtaagaaag cagctgtcaa tagaatggaa acaaaaatgg
    25741 cgagacatca atcagtctcg ccttgttttt tattgtatac attagatatg gagcaggtta
    25801 ccataaagat gattattagt cgttattaaa tagaatcctt cgtatttttt tgttctatca
    25861 ctacaatatc tttatttgga cgtttgaatt gtattccggc acgttctagc tcctgtttca
    25921 ctcctacatg gactttgaca tcttctcgtg tcatttttaa aacgtgatga atcgcatagt
    25981 cgatttcttg ccttgtgatt tttttcttcg tattgatcat cacgacttgc tttttatcat
    26041 atgtgtctac caatagcagt tgtgttcgat ctaacgaaaa taatttgtaa taattaatag
    26101 ccgtattccc aaaaaagaat tccactactt taggataaaa tgtcttaata tttaaattac
    26161 tattcacagg tgtttcgatt agcttcatct cattcctctt ttctatatag tcgatttaga
    26221 tccaatctta agttatgtta ccatctttcc tagcattaag gaatcggtta caattgaacc
    26281 tttaaagaca aaaggattta ccttttatca cttaatagta taacataatt tcgtgagaaa
    26341 aaaatacaat tttttcttga ccatctcgtt acgtaaagga ttatgcttac atttgtcagg
    26401 aggaaaaata atggagtaca caataaagaa aatgtcagag atatcaggag tcagtccgag
    26461 aaccttgcgc ttttatgatg agattggact gctaaaacca gctaggatca attcttcagg
    26521 ttatcggatt tatggcaaaa aagaagtcga tcgtctgcaa cacatcttat tttatcgaac
    26581 aatggcattc aagttggatg atatccaaga ggtcttagac aatccatctt ttgaccacca
    26641 gaaagcttta atcaagcatc agcaaatgtt gctggaaaaa cgggcacaaa tcgataccct
    26701 cttgacaact gtccaacaga cacttgatat gtacgaagga ggaagaaaaa tgagtgacaa
    26761 agaaaaattt gaagggttta aacaacaaaa gttgaaagaa aatgaagaat cctatggaca
    26821 agagattcga caaaaatacg gaaaaaaaaa ggttacagca tccaatgaaa aatggatgaa
    26881 tatggataaa gaaacgtatg aagaaatgca aactgttgaa aagcagatgt tatttgatct
    26941 cactctttac ttaaaagaac cagaagatga aagcttagca gaccgtatct tccaagctca
    27001 taagaagtgg ttctcttaca gctggcctga atatcagcca aaagcgcata aaggactagg
    27061 aatgatgtac gaagccgatg aacggttcac tgcatattat gacgagcgaa gtggtcatgg
    27121 tgcagcaaaa gctttaaatg aaattatcca aaaaaaggcg taatctttta catgatccaa
    27181 caaaaaagta cacgtaaaat gacctaataa caaaacagca gacacccaag ttagattttt
    27241 atgctaactt ttggtgtctg ctccattctt tcacaagttt tttcatccta ctttaaatat
    27301 attcatcgtt gaataaacgt ataaggtatt ttcactttat cctttttttc tgtaagaaac
    27361 aattgaaatg ccatttctcc gcaagcttcc agatggtggt cgatggttgg gaaaccaaga
    27421 agctcgctga tcagcaaatt atcgcgtcca atcaccactg gtgtcttatc ttgcagatag
    27481 ctttgcaaga tgcctgctgc aaccatatcc gaatttgtaa agacaccatc aactccaagc
    27541 tctttaaaaa agaagcctgc ttgttttcct ttctctgcat ctatacaatc ccaaaaaaca
    27601 agtgattcat caaaagatgg aaaaagttga tgacatagct gcaaagtgat ttttgagtta
    27661 taacttagcc tgccacttcg ccccaacgtg atgcccaatt gctttatacc ttgctgcttc
    27721 aaataagtaa gaccttctgt aattgattgt tctcgatcaa taaagacaca gcttgcctgt
    27781 tttcccttga tttcttcaca aaaaactaga ggtccatatt tttgatatgc caataaatca
    27841 tctagtgtat tggcacgaga cgtaatgatc aatccatcga aagctttagc tgcaaattct
    27901 tcaagatacc ttcgctcttt ttctttatga tagcccgtcg gtaaaagtgt cactttgtaa
    27961 tcataatcaa acgctgcttc aatgatccca ctgatcaact gatcaaaata cggatgattg
    28021 gtataaggca gaatcactcc aatgcttttc gtttttccat aacttaactg tctggcattt
    28081 gcattaggga tataatcgac ttctttcatg accgcaagta tttctttcct tttttcctca
    28141 tctacatatg gatgtccatt gattacacgt gaaatagtag aaactgaata acctgtgagc
    28201 tttgcgatat ctcgaatgtt tgccactgct gcttcgccac ctatacaaaa agattttctt
    28261 gtaaatagtc taccacagct ggaccgcatt caaaaaactg atacattttt ccttcatgcg
    28321 aaaaactgat ccgctgcccg ccccaatata tatcttttgt caaattttcg atttcattca
    28381 ttggtatttc ttttactata ttcctattca acccttgaaa actgtacaac gttaatacgg
    28441 atcccttgaa ctcgacaaac gcataaaaat aattgttcgt tgtgccatct gttatctcta
    28501 cataagtatt cattgcaagt cctccttttg atactttgag tatagtgtat gaaacgcgtc
    28561 tcatagcaag gagtttgttt tgccaaagaa aagttttatt cctctttcat tattaccaaa
    28621 gtctcttatt ttaaattgaa tacattataa tgatactgta aatatatctt tattattagt
    28681 gaat
//
LOCUS       DACBZK010000031        28683 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.031, whole genome shotgun sequence.
ACCESSION   DACBZK010000031 DACBZK010000000
VERSION     DACBZK010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28683
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.031"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            172..516
                     /locus_tag="IVD66_001426"
     CDS             172..516
                     /locus_tag="IVD66_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HAP6145656.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            517..936
                     /locus_tag="IVD66_001427"
     CDS             517..936
                     /locus_tag="IVD66_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAP6145657.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1028..1378)
                     /locus_tag="IVD66_001428"
     CDS             complement(1028..1378)
                     /locus_tag="IVD66_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145658.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1344..2675)
                     /locus_tag="IVD66_001429"
     CDS             complement(1344..2675)
                     /locus_tag="IVD66_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HAP6145659.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2931..3497
                     /locus_tag="IVD66_001430"
     CDS             2931..3497
                     /locus_tag="IVD66_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6145660.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3642..3729
                     /locus_tag="IVD66_001431"
     tRNA            3642..3729
                     /locus_tag="IVD66_001431"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3674..3676,aa:Ser,seq:cga)
     gene            complement(3781..4986)
                     /locus_tag="IVD66_001432"
     CDS             complement(3781..4986)
                     /locus_tag="IVD66_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP6145661.1"
                     /translation="MAKKEIDKRIKKHLTKKGEEKYQFSLYLGVDPLTGKKRKTTRRG
                     FSTPLAAERALKRLEADIQEKGLQASTAQKSKKFEYVYGLWFENYKKTVKESTWSSTK
                     QIFDTHILKVFGDKFIDKIDVFFCQEAVNTWSDSHPKIFKKIKNYTSNVFDYAASLQI
                     ITSNPMKLVSIPRGEALDIEDKNIEFYTKEELIEFLEAIRNDDDERYLFFSLLAFTGI
                     RKGEAFALTWSDIDFKSKTLNINKTVTRGYQGRLIVNTPKSKSGKRKIYLDNDLISLL
                     RKYYTKNKTIVTIQSENLIFHHDGLLYNPTVSRSWLNVIYKHHPELTKRITTHGFRHT
                     HASLLFESGASLKDVQERLGHADIQTTSNIYTHVTETQNKKVINNFVAFMKNSTQGES
                     KGESKNILG"
     gene            complement(5124..5564)
                     /locus_tag="IVD66_001433"
     CDS             complement(5124..5564)
                     /locus_tag="IVD66_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145662.1"
                     /translation="MKFIKFGIIGLLVVTVMGGCGTSTAETKESKNYSETNSTIKEVD
                     SDQTAEFATIAEKHIKEIYSIDNLKMDLKSIKVTQFPDDKNAETGEEYKNVYNGTGDF
                     TWQDKKYNFSLIYSKKDATNYTVLYLYSNLDPNKGVDTPLESDQ"
     gene            complement(5650..5850)
                     /locus_tag="IVD66_001434"
     CDS             complement(5650..5850)
                     /locus_tag="IVD66_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145663.1"
                     /translation="MKIGMRKPSIKKSISARTTGKAKRKVKKAVIPGYGKKGSGWIKD
                     PKKAAYNKVYKKTTFSFWDLFK"
     gene            complement(5879..6301)
                     /locus_tag="IVD66_001435"
     CDS             complement(5879..6301)
                     /locus_tag="IVD66_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAP6145664.1"
                     /translation="MYLPQIDNKINKLVKLYQTRNPFRIARELKILVLEEDLGEIYGY
                     YSKFKQIKMIHINSSLDEMGKWITCSHELGHCVLHPNENTPMLSKKTLVSELKIEKEA
                     NYFATHLTIDPTLDGFDHMTKYEKLVCFGLPDEFDRFL"
     gene            complement(6318..6740)
                     /locus_tag="IVD66_001436"
     CDS             complement(6318..6740)
                     /locus_tag="IVD66_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6145665.1"
                     /translation="MTTFERIKELAKNKNKNLQQVAKDLKYGENYFYSLNAGKQPTAE
                     KLQEIADYFDVSVDYLLGRTEKKRYYDLTEKDERDIQQELQSLIDDLSNADGMAFSKK
                     DNEMSEATREALIISLENALRIAKIEAKKKYTPKKYRD"
     gene            7029..7220
                     /locus_tag="IVD66_001437"
     CDS             7029..7220
                     /locus_tag="IVD66_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145666.1"
                     /translation="MSNLDNGRAAIKEFMKENGITMDDLATAYGHTRVRMQQILDGHW
                     SGPKANRTILEIIRDYRIR"
     gene            7231..7497
                     /locus_tag="IVD66_001438"
     CDS             7231..7497
                     /locus_tag="IVD66_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145667.1"
                     /translation="MNILSEEFLTRLRIAIVEVVKDALNQLSKKNLSETRYLKKIEAR
                     KYVGGVNDQGFEKLIAHGLKEIRIDGFLRYDKKDIDELMAKYKI"
     gene            7684..7869
                     /locus_tag="IVD66_001439"
     CDS             7684..7869
                     /locus_tag="IVD66_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145668.1"
                     /translation="MEIIYFYKDEENNIPIVVEHTNNLSSSLLNTEEFNEMIKQFPEA
                     KNNLYVLVGRTEFKLNA"
     gene            complement(7858..8247)
                     /locus_tag="IVD66_001440"
     CDS             complement(7858..8247)
                     /locus_tag="IVD66_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2513 domain-containing protein"
                     /protein_id="HAP6145669.1"
                     /translation="MKLNQDCVRDILLLIEDEISFGSFLRLDFFLASEKLSKYDSETI
                     KYTLAKLDETEFLKSNTRWVNNDLASFSTGMITWKGHKFLDTIRDEKVWSNTKSIISK
                     FSSVSISMVESIASNVITQLIEKQLRV"
     gene            8300..9025
                     /locus_tag="IVD66_001441"
     CDS             8300..9025
                     /locus_tag="IVD66_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAP6145670.1"
                     /translation="MQELVILKNKEAVTTSLQVAEAFEKKHKHVLEAIESVKRSVENS
                     ANVEDVLNFEKMFVEGNEPDTYGRSRRVFFMNRDGFSLLAMGFTGSKAISFKLKFIEA
                     FNEMEDVIRKNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNM
                     KVMEVLGGKESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLP
                     ETAIRMEIDQLNRQQRLFGDDNE"
     gene            9202..9441
                     /locus_tag="IVD66_001442"
     CDS             9202..9441
                     /locus_tag="IVD66_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145671.1"
                     /translation="MKKELSTLDQYLADPDWGKSNLQLVANKYEKSIDEAIVALTDAA
                     SITADDSKWTKRDLGILKRGVNWLEDQYREETKEK"
     gene            9447..10133
                     /locus_tag="IVD66_001443"
     CDS             9447..10133
                     /locus_tag="IVD66_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145672.1"
                     /translation="MFKPLIDSYSAVLKKFKGNDIGATINEEVNIERLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGREISLK
                     DESNTTVSDANILANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            10136..10966
                     /locus_tag="IVD66_001444"
     CDS             10136..10966
                     /locus_tag="IVD66_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAP6145673.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLSSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            10983..11834
                     /locus_tag="IVD66_001445"
     CDS             10983..11834
                     /locus_tag="IVD66_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP6145674.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALEKAKSYTNEVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNTELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            11831..12190
                     /locus_tag="IVD66_001446"
     CDS             11831..12190
                     /locus_tag="IVD66_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HAP6145675.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQA
                     PLILAKKYRNTFKEERF"
     gene            12205..12366
                     /locus_tag="IVD66_001447"
     CDS             12205..12366
                     /locus_tag="IVD66_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAP6145676.1"
                     /translation="MTTEEVIQMRIRNIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            12363..12668
                     /locus_tag="IVD66_001448"
     CDS             12363..12668
                     /locus_tag="IVD66_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145677.1"
                     /translation="MSVDKKATMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RKTPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            12668..13024
                     /locus_tag="IVD66_001449"
     CDS             12668..13024
                     /locus_tag="IVD66_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HAP6145678.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            12984..13229
                     /locus_tag="IVD66_001450"
     CDS             12984..13229
                     /locus_tag="IVD66_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145679.1"
                     /translation="MIKKLVQFSMDLYDIESGATLSVESDHLIINFGGKRQIILWVVD
                     DVLFPEIVHDFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            13250..13339
                     /locus_tag="IVD66_001451"
                     /pseudo
     CDS             13250..13339
                     /locus_tag="IVD66_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293000.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            13414..13881
                     /locus_tag="IVD66_001452"
     CDS             13414..13881
                     /locus_tag="IVD66_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HAP6145680.1"
                     /translation="MVLFDVKKYETPSAKDVDMDRTKHNVGVFLSAYLSARCRVGQPR
                     EPKVTASYSLVPPSTANHDFEAERMLIDKEEAQEEFEYLHKLFIRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            14206..14349
                     /locus_tag="IVD66_001453"
     CDS             14206..14349
                     /locus_tag="IVD66_001453"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145681.1"
                     /translation="MRIGNVYLISKVPYQKLLYSCKVRFIASDLRNLRKQFILSDADE
                     LAD"
     gene            14654..15040
                     /locus_tag="IVD66_001454"
     CDS             14654..15040
                     /locus_tag="IVD66_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145682.1"
                     /translation="MNDFHEAVLTFDVPTGMGQVYKKAIEDDNSRRWIKNEIKDADGN
                     IVISDIKPSWNGNHCSVSIDNSLTIEKYSGAIIDRTERKTHLTIALISRTLPNLKEQV
                     EWYERMGAKVISTNYKGENQNGNNQN"
     gene            15021..15422
                     /locus_tag="IVD66_001455"
     CDS             15021..15422
                     /locus_tag="IVD66_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145683.1"
                     /translation="MAIIKIRTSITGTEYWDSEKKKTVAVPKGQEPKFDTSEQTDMTV
                     VAKSIVGDGVLFKSGEEIHLSGEELDSDGNTAADFDGEKVTDDQFDGTTDELEDMTAK
                     ELRAYAKKHGIDIPGAVRAKGDIINLIREAE"
     gene            15419..15799
                     /locus_tag="IVD66_001456"
     CDS             15419..15799
                     /locus_tag="IVD66_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAP6145684.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            15911..16363
                     /locus_tag="IVD66_001457"
     CDS             15911..16363
                     /locus_tag="IVD66_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HAP6145685.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            16360..18087
                     /locus_tag="IVD66_001458"
     CDS             16360..18087
                     /locus_tag="IVD66_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAP6145686.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            18151..19338
                     /locus_tag="IVD66_001459"
     CDS             18151..19338
                     /locus_tag="IVD66_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAP6145687.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            19304..19879
                     /locus_tag="IVD66_001460"
     CDS             19304..19879
                     /locus_tag="IVD66_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HAP6145688.1"
                     /translation="MEMKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWD
                     DLSEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDT
                     TVARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYED
                     TEAALRSRDELEKNVEERKKLIKKINQALEA"
     gene            19892..21265
                     /locus_tag="IVD66_001461"
     CDS             19892..21265
                     /locus_tag="IVD66_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAP6145689.1"
                     /translation="MDTELLKKMKARREQRLTELREKVESGELREADLEAITKEIDAV
                     VDELNGIKSELSEADGSDEGSDADEGTGGSDGSTGSDENRSGEDNDQEEDSDSEDSSE
                     NRSGMITQQQRDGLLGSIKNGLEARAKMTNKQKDQQLRKAFANFVVGNISEAEARALG
                     IEAGNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVNKADANVNKKE
                     RSTDIAETAIQFDEILLDPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEIN
                     YMFNGDDAGNENPGALAKKAVAFEKPLDLTAAGAGQKLYDALIEFKNTPVTEVMKKGR
                     FIINRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPV
                     LYFGDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYE
                     ITKPVGG"
     gene            21267..21545
                     /locus_tag="IVD66_001462"
     CDS             21267..21545
                     /locus_tag="IVD66_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAP6145690.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            21526..21852
                     /locus_tag="IVD66_001463"
     CDS             21526..21852
                     /locus_tag="IVD66_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAP6145691.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            21842..22180
                     /locus_tag="IVD66_001464"
     CDS             21842..22180
                     /locus_tag="IVD66_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145692.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            22170..22535
                     /locus_tag="IVD66_001465"
     CDS             22170..22535
                     /locus_tag="IVD66_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAP6145693.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            22542..23168
                     /locus_tag="IVD66_001466"
     CDS             22542..23168
                     /locus_tag="IVD66_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP6145694.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            23168..23632
                     /locus_tag="IVD66_001467"
     CDS             23168..23632
                     /locus_tag="IVD66_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145695.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            23827..26136
                     /locus_tag="IVD66_001468"
     CDS             23827..26136
                     /locus_tag="IVD66_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAP6145696.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGGVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            26148..26852
                     /locus_tag="IVD66_001469"
     CDS             26148..26852
                     /locus_tag="IVD66_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP6145697.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            26849..>28683
                     /locus_tag="IVD66_001470"
     CDS             26849..>28683
                     /locus_tag="IVD66_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145698.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWR"
BASE COUNT        10013 a         4583 c         5918 g         8169 t
ORIGIN      
        1 ataaaaaaag cgttagcaac tatgcttaaa aagcatatcg actgaataaa ctaagcattg
       61 gacaggctga aagactacat ttaaaatgaa atgcgaagaa acaatagaaa ataaagttgc
      121 cttagaacca tagttgaatc acctaacagt cgtgaaggga gaataagaga aatggcagaa
      181 aaacaaaccg caggacgaga tcaattagga gattttgcac caaaatttgc agaattgaat
      241 gatgatgttt tatttggaca agtatggtcc agagaagaat tatctgctca tcagcgtagt
      301 atcatcacca tatctgcatt aatttcagga ggaaattttg aacaattgcc agctcatctg
      361 aagattggca agcaaaatgg cattactagt gaagaaatag cagaaatcat tacccattta
      421 gctttttatg taggatggcc aaaagcttgg tcagctttta gtttagcaaa agaaatctat
      481 ttagaagaaa atagcgaaga taagaaagag gcgtaaatga cgacaaaaca cgaagaaata
      541 cacaatggcg tgatttttcc agcaggtgaa aaaaacgaag cttacgctca agtatttacc
      601 gggcaaagct atctgaatat gttagtgaat gatcccgaag tttctgttgg tgtaggtaat
      661 gtaacttttg aaccaggttg tcgcaatcac tggcatgtcc ataaagacgg ctatcaaatc
      721 ttacttgtga ccggaggaga aggctggtat caggaagaag gaaagccagc aagacgatta
      781 atggctggag atgtcgtcgt aacgcacaaa gggattaaac attggcatgg tgcgacaaaa
      841 gacagttggt ttgaacattt ggcgatcact gctggtaatt cagagttttt agaacctgta
      901 acagatgaag tgtatgaagg attggaaaat caataatgtc aagcttgaac agctcctgaa
      961 agtagatttt aatcgaactt tcaggagctg cttttttgat tcagtctttt ataaatagaa
     1021 aatagggtta ataataggaa tgagaagcac gtcgaaagat cttaatattg ataatcggct
     1081 gggcatacat gatttccacg tcatcaatca aactacctaa cagatgataa tcttcccgat
     1141 catgtcgggg attacctaat agttcttgat aatagatttc catactaggg tcccgaggat
     1201 tgttcagcaa atcagcaagt acatctaaat cttctggctg agtttctgcc gtaccctgta
     1261 tctctatgaa aagcccttcc tcagcaaatt ctactccaat acgtatttca gttatttcat
     1321 gggaatataa ataagtaaga agctcatcga tgattctttt tgataattct ttttccaagt
     1381 gtcttttttt cctttctgac agcggtaaag ttatctagta tcggtacaag gatacctgca
     1441 acgaaaccag ttgaaaaacc actgttatat agatttagtc ctccgtgcaa agtgctgacg
     1501 ttatggacaa gagcaatatg tagtacacca gctattacac cgtaaaaact gccgtaaaaa
     1561 ccgcttatgg gcgcgagacc tgtcccaaac acagctgcaa caagcatgcc agtactggtg
     1621 atctcatgaa aagttccaaa caaagaagca ataaatattc cgactagtat cggaaaactg
     1681 ttttttaaat gacaaccaaa agcactgaaa cccaccgcag ataaaatagc accgatgaca
     1741 ggtccattta actgaccgcc aaccagcaaa acataagaag acagcatcag accaactaag
     1801 cctatgttga tcaaagtagc accaatacca gaattagcaa tgaaatcagt tgtcaatttt
     1861 ccagatgaat cgaaaatttc tcgaatcccc aaaagccgaa aggaattata atagaaacca
     1921 attccgactg tcagcgaaaa aaagccaaaa ataatccaaa tgagaggaaa gtgatattca
     1981 ttgaaaacca atgtattttc gacgattgaa tagctgaata acctcaaaac agcagtaaaa
     2041 gtcatcgcaa tcaacccaga ggtgaatcca atattataaa gtgtgaatcc acgatggaaa
     2101 actaaagttt gagcagctaa gggcggaaga agtagaccaa ttgctatgcc agctaaattc
     2161 cccaataaaa tacctatcag taaaggaaaa cgcataccaa aagtgatata actaacgacc
     2221 ggtgataatg cgctaccaaa cagtccgatc atgatgtact gagaaaaagg tttattgaca
     2281 aatacagcgt atagatacac acctaaaatg attgagatag aattataaag gtttttgcca
     2341 aaaaaagaga aaccggtaac tgttagaatc gaagcaaata agggaccgtt taaaatcacc
     2401 ttgtgccgat aagctaaaag cacagaaagt aaggtcaaaa tccctacatt tatgaatgcg
     2461 cttccgaaac cgcctaaagc aaaataatct gtcaaaagat tgcttggcga ggtaagaata
     2521 gttagcaatc cactccaatt atcagtagga gtattagaaa gcaagccaat aaaaagaaaa
     2581 aaaacacctg taaaaccaag ataaaaatac tttcttttct gtgaaacgat tcgtttttga
     2641 ggatgaatat aaataacgtc agtttcgttt tccattacac accttctttt tcattttctt
     2701 taactataac ttgaaatgaa agatttggac aactatcatt taggtcaaaa ctaaaaatgt
     2761 aagggaaccc attgaattta accaaatttt tttaattttg caaaaaaaag ttaaagaaga
     2821 ctgaaaaaaa atttaaaata taacgttttg agtaaaatgt ttgcaaaaaa tgctaaaaat
     2881 agggtacaat aaaacaacat atactgcagt aaagaagtgg gggagtttta atgagaagaa
     2941 aagtctatac caaggatcaa attctaaaag ctgcttatga tgttgttgca aaggaagggt
     3001 ttaaaggatt tactgcgaga aatattgcta aaaagatggg gatttcgaca cagccgattt
     3061 atctggaatt caaaaacatg gaagatttaa aaaatacgtt gctggattct atctttgaac
     3121 aactaaaaga agatgttttc cctattgaac gtactggtga taaaatcatt gatctcggtt
     3181 tgaactatat ctactttgca aaaaagcatc atagtcttta catggcattg tacattgatg
     3241 aacatgggga cggaaagaaa atgcatgatt tttcatacaa ttatttccgt gaaatagtta
     3301 aagaagatga aagatacaat caattatcgg atgaatatgt cgatgctctg catactggta
     3361 catgggtagc agtgactggc ttagcgtcat tgatgtcatc aaacatcatg catccaacag
     3421 aagaacaaat cattgcactg atcaaacgga caattgactc gattttagca ttagataatc
     3481 ctgaaataat cagatagtgt tctatcagta tgaatttgat cggtaagtcc gttggctgca
     3541 aactgtcaat ggactttttt gctaaaaaaa gcgatttctg ttatttatct attagaaata
     3601 ggcttgacat ttcgtgaaaa aagtttaaaa atagtactta cggaaggttg gcagagtggt
     3661 aatgcaccgg actcgaaatc cggcgaaccg gctaataccg gcgcgcaggt tcaaatcctg
     3721 taccttcctt atatatcaac gattagacgc gatttcgatc gtgtcttttt ttgttgtaat
     3781 ttagcctaaa atgttttttg actccccttt tgactccccc tgagtactat tcttcataaa
     3841 tgctacaaaa ttattgatga cttttttgtt ttgagtttca gttacatgag tgtaaatatt
     3901 tgaagtagtt tgaatgtctg catgccctaa acgttcctga acatctttta aagaagctcc
     3961 tgattcaaaa aggagagagg catgagtatg tcgaaaacca tgagtagtga ttcttttagt
     4021 caattctgga tgatgcttat atatgacatt aagccacgaa cgtgaaactg tagggttata
     4081 gagaagacca tcatggtgaa aaattaagtt ttcgctttgg attgtaacga tcgttttgtt
     4141 ttttgtataa tactttctca ataaactgat caaatcattg tccagataaa tttttctttt
     4201 tccagatttt gatttaggag tatttacgat caatctccct tgataacctc ttgttacagt
     4261 tttattaata ttgagtgttt tgctcttaaa atcaatatcc gaccaggtca gtgcaaaagc
     4321 ttctcctttt cttatacctg taaaagccaa tagggaaaag aataaatatc tttcatcatc
     4381 atcgtttctt attgcttcta aaaattcgat taattcttct ttagtataaa attcgatatt
     4441 tttatcttcg atatctagag cttctccacg tggaatagaa actaatttca taggattgct
     4501 agttataatt tgtaaagaag cagcgtaatc aaaaacatta gatgtgtaat tttttatttt
     4561 cttaaaaatt ttaggatggc tatcggacca agtgtttact gcttcttgac agaaaaaaac
     4621 gtctattttg tcaatgaact tatctccaaa cacttttaag atgtgtgtgt caaaaatttg
     4681 tttggtggag gaccaagtgc tttctttaac tgtcttttta taattttcaa accataagcc
     4741 gtaaacatat tcgaatttct tgctcttttg agctgtagaa gcttgcagtc ctttttcctg
     4801 tatatctgcc tccaatcttt ttaaagctct ctcagcggct aatggcgtac taaaacctcg
     4861 tctcgttgtt tttctttttt ttcctgttag cggatcaact cctaagtaca gactaaactg
     4921 atatttttct tctccttttt ttgttaagtg ctttttaatt cgtttatcaa tttctttttt
     4981 tgccatcttt tatctttcct ttcgtacgtt tgttcggttg tacagcggat ttcgagatgg
     5041 taaaataggg tacaacaaat agacctactt taccgtagct ctttgcacat ttgcgttctt
     5101 ggtcgggcgg caaatgtgct tttttattga tcgctttcta atggtgtatc tacaccttta
     5161 ttagggtcta gattgctata tagatatagg acggtataat tagttgcatc ttttttcgaa
     5221 taaatcaaag aaaagttgta ttttttgtct tgccaagtaa aatctccagt accattgtag
     5281 acatttttgt actcttcacc agtttctgca tttttatcgt caggaaattg agtaactttg
     5341 atagatttta aatccatctt caaattatct attgaatata tttctttaat gtgtttctcg
     5401 gcaatagttg caaactcagc ggtttgatca gagtctactt ctttgatagt actgtttgtc
     5461 tcactataat tttttgattc ctttgtttca gctgttgatg ttccacatcc tcccataact
     5521 gtcactacta gtaatccaat aattccaaat ttaataaatt tcattttcta ctccttatct
     5581 ctatgatatt attttattgg ggaatcttag aaataaggtt tcgagtccgt gttgctgcac
     5641 gggctttttt tatttaaata agtcccaaaa gctaaacgta gtctttttat aaactttatt
     5701 gtaagcagcc ttttttgggt ctttaatcca gccgctacct tttttcccat aaccaggaat
     5761 aactgctttt tttacttttc tttttgcttt tccagtggtt ctagcgctta tggatttttt
     5821 tatacttggt tttctcattc ctattttcat ctatatcctc cttacgttgt attataattc
     5881 acaagaaacg atcgaattca tctggtaatc caaagcagac gagcttttca tattttgtca
     5941 tatgatcaaa gccgtctaaa gttggatcaa tagtcagatg agttgcgaaa taatttgctt
     6001 ctttttcaat ttttaattca gatactagcg tttttttaga caacataggt gtgttttcat
     6061 tcggatgcaa aacacagtgg cctaattcat gactacaagt tatccatttt cccatctcat
     6121 ctaaactaga atttatgtgg atcattttta tctgtttgaa tttactatag taaccataaa
     6181 tttctcccaa atcttcttct aaaactagta tcttcaattc tcgtgcaatt ctaaaaggat
     6241 tgcgtgtttg atatagtttt accagcttat taattttgtt atcaatttga ggtaaataca
     6301 taaacaacgt actcctttta atcgcgatat tttttaggtg tgtatttttt cttagcttct
     6361 attttagcta ttcgcaaagc attctctaaa gaaataatga gagcttcacg tgtcgcttca
     6421 ctcatttcat tatctttctt cgaaaaagcc attccatcag cattagataa atcgtcgatt
     6481 aatgactgta attcttgttg aatatcacgc tcgtcttttt ctgttaaatc atagtatctt
     6541 tttttctcag tacgtcctag caaataatct acagatacgt cgaagtagtc agcaatttct
     6601 tgtaactttt cggcagttgg ctgttttcct gcatttaaac tataaaagta attctctccg
     6661 tacttcaaat ctttagcgac ttgttgaagg tttttattct tgtttttcgc tagttctttt
     6721 attctttcaa atgttgtcat tccaacgttc ctttccaaca cgaaaaaata atttacgaaa
     6781 aagagtaaaa atagctttac aattttacga tatagagtta ttatttatcc gtaagttaat
     6841 ttgatagaaa aaagcaaact aaaaacacac cttatagcat aaagtttggc gaccaagtgc
     6901 aaataaaagg ctttgttata ggcttatttc tctatgtatt cattttactc tatagtgtaa
     6961 aaatgtcaat ggaaattata tttttctatc actttaactt acaaatttat aaaaaaggaa
     7021 gtgggttaat gtcaaacttg gataacggtc gtgcggcgat caaagaattt atgaaagaga
     7081 atggaataac tatggatgat ttggctactg cttatggtca cacgcgtgta cgaatgcaac
     7141 aaattcttga tggacactgg agtggaccaa aggcaaacag aactattcta gagatcatcc
     7201 gtgattacag aattcgatag gaggctagtc atgaatattc taagcgaaga gtttctgact
     7261 cgtttgagaa ttgcaattgt tgaagttgtg aaggacgcac ttaatcagct ttcaaaaaag
     7321 aatctttcag aaacacgata tttgaaaaaa atcgaagcta gaaaatatgt gggaggtgta
     7381 aacgatcaag gctttgagaa gttaatagct cacggtttaa aagaaattcg tatagatggc
     7441 tttttgagat atgacaaaaa ggacatcgat gaactgatgg ctaaatacaa aatttaaagg
     7501 aggaaaaaca tgggaaagtt taatcgaaca ttagtattca gcgcaccgct aatcatctac
     7561 gctttaggac tttggggaaa tagacaagcg ttgataggaa cgatcgttta catggtttgg
     7621 atttttatag ggctggatga agctgagtat agagcgaaaa agccagtcgg gagggactga
     7681 ctaatggaga ttatttattt ctacaaagat gaagaaaaca atatcccaat tgttgtcgag
     7741 catactaata acctatcatc aagtttatta aacactgaag aattcaatga aatgataaag
     7801 caatttcctg aagcaaaaaa caatttatac gtactggttg gaagaactga atttaaatta
     7861 aacgcgtaac tgtttttcta taagttgagt tattacattg gatgcgattg attctaccat
     7921 gcttatagat acgcttgaaa atttagagat aatcgatttt gtatttgacc aaactttttc
     7981 atcacggatt gtatctaaaa atttgtgacc tttccacgta atcattccag tagaaaaaga
     8041 tgctaaatca ttatttaccc atctagtatt tgatttcaga aattctgttt catcaagttt
     8101 agcaagtgtg tattttatag tctcactatc atatttcgat agtttttcag aggctaagaa
     8161 gaagtctaat cgtagaaaac ttccaaaaga aatctcatcc tcgattagaa ggagtatgtc
     8221 acgtacgcaa tcttgattta atttcattat aaacaccacc agtttttacc taaattatac
     8281 caaaaggaga gaaataaaaa tgcaagaatt agtaattttg aaaaataaag aagctgtgac
     8341 tacgagcttg caagtagctg aagctttcga aaagaaacat aagcatgtgc tagaagcaat
     8401 tgaatcagta aaaagatcgg tcgaaaattc ggccaatgtt gaagatgtgc tcaattttga
     8461 gaagatgttt gtagaaggaa acgagccgga cacgtatggg agaagtcgga gagttttttt
     8521 catgaataga gatggatttt ccttgttagc tatgggattc actggaagta aagcaataag
     8581 tttcaaactc aaatttattg aagcattcaa cgagatggaa gatgtcattc gtaaaaatac
     8641 tgttcctcaa acgattgaag acatgatgat ctaccaatta gaagaaatga aagatgtaaa
     8701 aaaagatgtc tccatgctta aagatactat gcgaattagc ggacaacaag agtttgaaat
     8761 taagcaaaaa ggaaatatga aagttatgga agttttagga ggtaaagaaa gccgagctta
     8821 tgaagaaatc agcaaaaaag tattctcaaa attttggtct gaatttaaac gtaccttttc
     8881 aatcccaaga tatggcgagt tacctcgtaa gagattcgat gatgctgttt catttattga
     8941 aatgtggttg ccagaaactg cgatccgtat ggaaattgat caactgaaca gacaacagag
     9001 actttttggt gatgacaatg aatagagctg aagcgctaag aatagggacg gtaattgcta
     9061 atcgctggtg gagacataac aaaccaatca tcctaagcca acaacaaatc gacaagaaaa
     9121 aggcatggca acaaataaaa aagtgactca gccggcaagc atagagtcac atacaaaata
     9181 catctaagga gatgttacca catgaaaaaa gaactttcca ctctagatca atatttggcc
     9241 gatcctgatt ggggcaaatc gaatttacaa ctggttgcta acaagtacga aaaatcaatt
     9301 gatgaagcaa ttgttgcatt gactgatgca gcttccataa ccgctgatga cagtaaatgg
     9361 accaagagag acttgggcat tctaaaacga ggcgttaatt ggcttgaaga tcagtacaga
     9421 gaagaaacaa aagagaagtg atatgagtgt ttaaaccact aatagattca tactcggcgg
     9481 tactaaagaa atttaaaggt aacgacattg gtgcaacaat caacgaagaa gtaaatatcg
     9541 aacggctgaa aacgatgtat gacggatatg atggcgatcg agtcattgaa attcgcttta
     9601 ttgatccacg acggttcaca gtacagcaaa gaaacttcat ctatgcgctc ataggcgata
     9661 ttttcatcga tacaggcatg ccaacggact tctggaagga attcttctac ttccgttttg
     9721 aaggtgtcac agggcgcgaa ataagcctca aagacgaatc gaatacaacc gtgagtgatg
     9781 ccaatatctt agcgaatatc atcctagatt tcatctttga acatcatatt cctttcaaag
     9841 aaggatatga gattttacca gcgaatcaag agtattactt ctacaaatgc attacaaaaa
     9901 gagtctgctg catctgtggc aaaacaggag ctgatatcga tcactttgac aaagcgctgg
     9961 gaagacgaaa gcgcaaagaa gttgatcatt cagagtacac atttgcagca ctctgcagaa
    10021 tccatcacac agagaaacac aaaataggtg tgatcaattt caaaaataaa tatcaaatca
    10081 aagggatcaa gttaaaccag gaaacaatta aaaagttaag gataggagga taaatttggc
    10141 tgagataagt tggatcaaac ttaaaactac tatgtttgac gatgaaaaaa tacgattaat
    10201 ccaagctgtt cctgagtcgg atgccatcat cgttatatgg attcgattac tagttttagc
    10261 aggaaagact aacgacgatg gtctgatata tatccagagg aacatgcctt ataccgaaga
    10321 aatgcttgct acattgtttg gcaaaaacgt aaatacggtt cgcttagcgc taactacatt
    10381 ggcaaatttc aacatgattg atctaagcag tgatggacta attgccatca gtaattggga
    10441 aaaacatcaa aatatcgagg gtatggataa agtaaggcta aaaaatgctg aaagaaaccg
    10501 taaatacagg gaaagaaaga gacaggaacg tctcaaattg gaaaatgacg ttagcgtgac
    10561 gtcacgtgac ggtacagata aagatataga agaagataaa gatatagata aagaagaaaa
    10621 gaaaggtaag tattctgacg aacacttacg ccttgctaaa aagttgcaaa gtaatttaac
    10681 tgaagatttt ccaaaagaaa tgaacaaagt agatatcgaa aaatgggcag acacaatcag
    10741 gttgatggaa gaaagagata aagcatctat agaagcgatt gagtatgtga tcaattggct
    10801 acctacaaat gaattttggt ttggaaatat tagaagtgct aagaaattga gagaaaaatt
    10861 tgagaagctc aaattcgaaa tcaaagcaga caagaagaat cataaaaagc aaagtcaaaa
    10921 actacagtac agcaatccta gtgaatatga cgacttgcca atttaaaaag gagatgcatc
    10981 acatggaaag cctagcaaat gctatggaga aactaataag aagagtatta gtgcaaagcg
    11041 gaaaatgtcc agaatgtagc gaacctttgt atagttggcg agctaaaaat aaggatggtt
    11101 cagaacgttg taaaccaaca tgcatgagtt gtggttataa agcgttacgt gtgaaagagg
    11161 atatacagac cgaacggata tataacgata gcttaaaagc acgagcgttg agtttttttc
    11221 aaaatggttc ggtattaaca gataaaactt tgtttaaatg caaaatggaa aattatcacg
    11281 tagtggatca agaaacaaaa atcgctttag aaaaagcaaa aagctatacg aatgaggttc
    11341 tgctgaacca tcctgcacat ttcattctat cagggaaatc aggaagcgga aaaagccact
    11401 tatcaatggc cacagcttgg gaaatacttg agcgctcaaa ttatgacaag aaaatacttt
    11461 ttataagcta tcaagaatta ttagagcaaa taaagttttc ttataacaat actgaactga
    11521 gaaaagaaat tgaaggatcg cttatagccg atattaaaac aactgatttg gtggtttttg
    11581 acgatattgg agctgaatta ggtagtgggg tatcaaatag taggcagttt acaaacaaca
    11641 cgttaaacac gctcttagaa gccagacaga acaaggcaac gatcatcaca acaaacttat
    11701 ctggtcctga actaagagaa gcctacggtg aaagaattgt ttctaggata tttaagaatt
    11761 cagaaggtta tgcgctgaaa ttccaacaaa cagcagacaa gcgcataaaa ccagtgaaag
    11821 gtagtatcgc atgaataaat accgtaataa aaaaactgtt catcgaggta tcaagtttga
    11881 ttctatcgca gaagcagagt attacgatct agccttgtgg caagctgaag caaatggctg
    11941 gaaagtaaaa cttcaggaaa gatttgagct gatgccgaaa tttgaactag acggaaagaa
    12001 gtatcgcaag atcgagtata ttcccgactt cacattttat aaaaacggca aacttgtcaa
    12061 agtcgtagat gtcaaaggaa tgcagacaaa agactttaag atcaaggcaa agttgttctg
    12121 tcatcaatat caagcgccgt tgatattagc taaaaaatat cggaatacgt tcaaggaaga
    12181 gcgtttttaa cgaggtggtc catcatgaca acagaagaag tgattcaaat gcgtattcga
    12241 aacattcagc gtgaaattga cgatctagaa cgaacaaagg cagtgatggt caatgaaacg
    12301 gcgagaaagg caatcgattt gcacatagag aacttaagaa gggaaattcg tagattggag
    12361 gaatgagcgt ggataagaaa gcgacaatga aacgaattgc tgaattaacc aagtcagaat
    12421 cttggcagga agacaaagaa atagttgcag aagtccaaaa gctcggtaaa tcaatgtgga
    12481 ctgaaaagcc taaacggaaa acgccgagaa aaattgcaat ctggcatggt gatcgaattc
    12541 tagtaacagg tacagctgaa cagttatctg aaattactgg attaagcaaa aacattatct
    12601 gggatagagc taggagctta tggattgatt caaaaggacg acagtttagg tatgtggagg
    12661 agagataatg gatctcatta cacaatacag tgacatcatc ctcaagaaaa tcatgatgaa
    12721 gattcagaaa gacaaaaaat caaaagaacg agctgaatta gttaagttag aaatggctga
    12781 aacaggagca ggagtgcgaa gtagcaggca ttggaaagca gcagcaaaca ttgaatttta
    12841 ttacaacgaa attcaaaaag ggttcgatca gatgcgtgag ctggatcggc aaacaaattg
    12901 gagcaagaaa cttcatcaag atcgtttcaa atttgtagag aagtataaag aaatattaga
    12961 agagtatttg aggaggacag caaatgataa aaaaactcgt tcaattcagc atggatttat
    13021 atgatatcga atcaggagca acactatctg tggaatcgga ccatctaatc ataaattttg
    13081 gtggaaagcg ccagattatt ttgtgggtag ttgatgatgt actgtttcca gaaattgttc
    13141 atgatttcga agaatcaaaa gcggttgagt ttgaaatagt gaaaaaagta atggaattga
    13201 ttgaaaaata cgaggaggac agcgaatgat accgaagttt agagcgtggg atagagaaaa
    13261 agacagaatg aaggcagtag ctttggttga atttgctgag gcgtataaat caggagaact
    13321 catttcacgt acaaaataaa aaaagtcgga ttcctccgac tatgaataat atttccgaca
    13381 taagtattat atcataattg ggggaatcag aggatggtac ttttcgatgt aaagaaatat
    13441 gagacaccaa gcgcgaaaga tgttgatatg gaccgcacaa aacataatgt tggtgttttc
    13501 ctttcagcat atctatcagc tagatgtaga gtagggcaac ctcgagaacc aaaagtgaca
    13561 gcatcatact ccttggttcc accatctaca gctaatcatg attttgaagc cgaaagaatg
    13621 ttgattgata aagaagaagc acaagaagaa tttgagtatt tgcataaatt gtttattaga
    13681 ggatactctg ctatacagca tccgcacaaa cccgatgtga ctgaaaggcg caagaagata
    13741 ttctatgatc gttatatcaa tggtctgccc atttatgtaa ctgctcaaag gaataatact
    13801 agcgaagaat cggttaaagt agaatcaaac agaattatca tccaatttgc ttcatcgtta
    13861 gaactggttg ctttcaagta gccagttttt acacttttta taccctttta ttaccaattt
    13921 ggtttccatt ttataccttt tttataccaa tcacttacct attcaatgtt gtattatgat
    13981 agtgtcgaaa gattagtgat aggtctgaga caaaataata ataaaaggaa catcgtttta
    14041 ttattgtttc acaattaagc ttcgatagat agcgacggaa atattaagaa taaggatgtg
    14101 aattccaact ccttctaaat tgttcttatt atctatcatc cgttgctgtc tattgtcatt
    14161 atgtcattgt ggcggaaagg gtagacgcat tgagggagag agtacatgcg tatcggaaac
    14221 gtatatctga tatcaaaagt cccttatcaa aaattattgt actcatgcaa ggttcgattc
    14281 attgccagtg acttaaggaa cctacggaaa caattcatct tatcggatgc cgatgaattg
    14341 gctgactagt cgggatgcta ctagcagtta gaaggcataa aatactagcg cagacgtgcg
    14401 ccactctcag gtgtaggtta ggagagaaac attagttggg gttattagga atacgataac
    14461 ctgcttgcga caaagctttg tactgtcgcg ttggtcatga acagagacgg tattctgttt
    14521 cagtattcgt tagcaaccga gggatgtggc agtggtgagg cgcaggaagt attagacttg
    14581 tctgtgtgta ggttgctatt acatattaga tcactctttg agtggtcttt ttattttgaa
    14641 aggagtttta tctatgaatg attttcatga ggctgtactt acttttgatg ttccaacggg
    14701 tatggggcaa gtttataaaa aagcgattga agatgacaac agtagacgtt ggattaaaaa
    14761 tgaaataaaa gatgccgatg gaaatattgt gattagcgat atcaagccaa gctggaatgg
    14821 caaccactgt agtgtcagta ttgataatag cctgactatt gaaaaatatt ccggagcaat
    14881 aattgataga acagaacgca aaactcacct aaccatagca ttgatttcta ggaccttacc
    14941 gaatttaaaa gaacaggttg aatggtatga gcggatgggc gcaaaagtaa tcagtacaaa
    15001 ttacaaagga gagaatcaaa atggcaataa tcaaaattag aacatccatc acaggaacag
    15061 agtattggga ttcagaaaag aaaaagactg ttgcagttcc gaaaggtcaa gaacctaaat
    15121 ttgatacaag tgaacagact gatatgactg tagttgccaa gtcaatcgtt ggtgatggtg
    15181 tcttgttcaa gagtggtgaa gaaattcatt tatcgggaga agaattagat agcgatggaa
    15241 acaccgctgc tgactttgat ggagaaaaag ttaccgatga tcagttcgat ggaacaacag
    15301 atgagttgga agatatgact gcaaaagaat tacgtgcata tgctaagaaa catggcattg
    15361 atattcctgg tgctgtccgt gcaaaaggag acatcatcaa tcttatccgt gaagcagaat
    15421 gaagtactgt cagtttgacg gatgcacgaa caagatagca aagggtatct actgtactga
    15481 acacaagaga tcaagcagat cacgcaagaa gaagcagcaa gcaaagtctg tttatcatca
    15541 tgagaacaaa ccattctatc gaacgcaagc atggaaagat atgcgtcaat ttatttatga
    15601 aagagaaggt ggtcattgtc agcggtgtgg tcagttcata tttggaaaga gagcacacgt
    15661 ccatcacatt gtaccaatca aagacaacga actgcttaag cttgatccaa acaatctcat
    15721 gctattatgt tcaaaatgtc atccaattgt tgaaaacgaa acggaagaca aaaaagtttt
    15781 tccttcgtat ttcaattgaa gcccccctat tcattttcaa aattttttcg cgtggggaga
    15841 tagggtagcg gggagtcacg cgcatcgtta ggtcaaattt ttcaaaaaac aaaggggggt
    15901 gtatacaaaa atgacgacta aagcgcaacg taaagcgatt attgatgaaa aagtaagtgc
    15961 tgaaaaagct cgtatcttag aaataatgaa tttgtctgat ttgtacacca tcactcttga
    16021 tccattaatc gaatcatact tggatatttt tgaaatttac caacacaaat atttattgtg
    16081 gaaggaaaaa ggatttccgg agacgcaaaa attcacgaat aaatcaggag ctactaatca
    16141 atcaaaacat ccattggcac aacaagtaga aacttgggca gataagaaga tgaaagctct
    16201 agatttatta ggattaacaa acaaagcaaa aactggtaga ctaattgctg gaggatcgac
    16261 cgcaagaaaa gatgaagaaa ttacacgccc agaagtaaag ccagtagatg aactagcagc
    16321 gcacagaaat aaatggcgta agaaggcagg tgctgaaaaa tgattgaacc tggtgtaaat
    16381 tatgctgatt tatttgcaaa agaagtaaga aagaaaccta agaagtatcc taagaccgtt
    16441 cgtttagcaa tagatcgctg gtatcagtgg aaaaaaagaa aagatatttg gtttgatgta
    16501 gatcgcgcga atgaaatgat ggattgggta gaatcattta ttgttcacac aaaaggagaa
    16561 atggtgggaa aaccgtttct tttagaaccc tgggaaaaat ttatttattc ttggatttat
    16621 ggttgggtta aagaaaatga aaaaggccaa attgtacgcg ttactcgtga ggcttatgtc
    16681 cagattccaa aaaagaatgg taaaacattg attgctgtcg gttcattagg atatgcaatg
    16741 tacggagaag gggcgttatc agttgattgc tatgcttgcg catctgattt tgctcaagcg
    16801 caatatgctg ccaaaccttt tgcagttaca atcttaaaca atccaatcct acttgaagga
    16861 actaaaatat ttagggggcc aaagggaact gtttctagta ttacttatga ctatattcat
    16921 gaagatatgg cttactcaaa taaatttatt gttcaaacca agaatattga taatatcgag
    16981 ggatccaatc catattttgt attgaacgat gaattgcata aacaggagaa aatggaacag
    17041 tatgacaatt ttaagtctgc tcagatatct ttaccacagc cattgatgtt taatatctca
    17101 actgctggga aaggttcgtc gtctgttgga atgcgtgtat atcgcgaagc aaaagaagtg
    17161 ttgaaacgtg atgataatga ttcaaacttt gttctaatct atgagccaaa taaaaattat
    17221 gattggacgg atagaaaagt ctgggaaatg tgcaatccta actggggaat atcagtcgat
    17281 ttatctgctt tagaatcggc atttaaaaca gcgcaacggt cagctcattc caaagctgaa
    17341 tttctaacga aacacttgga tgtatttgtg aacggcgcgg ataatttctt tgaacaggat
    17401 caagtagagc catgtttagt taccacacaa gaacttggtg atttaagtgg cgaaccatgt
    17461 tatatcggtt tagatttatc acgtacacga gatttgacct gtgtatcttt aaacttccca
    17521 acatgggatg aagatggtaa agcggttctt aaagtaaagc aactttattt tattccgaat
    17581 gaagatttag agtttcgaga aaaagaagat aatgttcctt acagtgattt ggctgaacaa
    17641 ggtttcgttg aattttgcga cggaaaaatg attgatcaag atcagatttt gcagtacata
    17701 gaggactgca tgaatttata tgatattcag caagtgaatt atgatccagc gatgagtgac
    17761 aaacttgttg agaaattaga aaacttagga ttggaatgcg ttgaagttgc tcaatatcct
    17821 aaagtattga atgctccttt tgacgatgtc gaacggttgt tttatgagaa acgaattcaa
    17881 tttgataatc cattattcct ttattgcact ttgaacgttg tagcaattac taacatcaat
    17941 ggacaaaaag cgccaagtaa acgtcaatca aagaaaaaga ttgatgggtt cgtggcgttt
    18001 ttgtgtggtc ataaggaaac gatgaatcaa atgacagata ttgattcaga tgagttagat
    18061 gattacctaa gttccatcta tagataaata gaaaggcggt gaaaaaaatt gaaattacgt
    18121 gatcggttat cgaatgcagt ctattctttt atggaaaaac gtggatatat cgaggatatt
    18181 tttggacact acacacgtta tggtcaaaga tatgtgacgg attcatctat catggaatct
    18241 tctgatgttt atgaattagt tcaagacata tctaatcagg tggcattggc cacaccaatt
    18301 gttattggtc ccgacggcaa cgaagtcaaa gatcatcact tactaaatat tttgaagagt
    18361 cccaatgatt atttgacagg attcgaattt accaaattgg aaacaaatac tttattgatc
    18421 aatggtgaga cattcccatt aacggatagg gatcagcttc atttggcgta cggtgtaaca
    18481 actaaaatca atgaacgact tcaagaagaa tttgaaatga atggtcaaaa aatacctggt
    18541 caaatgattc gacacattaa gaacatcgga actgattcat taaaaggtgc tggaataatt
    18601 gatcttgcaa gaaacactct agaaggcgtt ctgagcgctg aaaaagtttt gacggacaaa
    18661 tatactaaag gcggtttact tgcgttcatg cttaaactag acgcccacat caatccaaat
    18721 aatagcgccc aaacaaaaat tgtcaaagct atattggatc aactggaagg aacgcaaaat
    18781 gagagtgatc attctgttaa gatgattcct ttgggaaaag gatattccat cgagacatta
    18841 aaaagtcctg ttgatgacgc ggcaattttg aattatttag gtgtttacaa aaaagactta
    18901 ggaaaatttc taggaatcaa tgttgatacg tatcaatcgc tgatgaagac agatattgaa
    18961 aaagcgatga tgtatctgca caacaaagca atcaaaccaa tattgaaaaa caagagcgaa
    19021 cattacaccg ctcttttttt tatgcctaat tctggctata gagtggaatg gaaaattaat
    19081 attttggatt ttgttcctta ctcaacaaaa acaaatattg gctacaacat cgttcgtacc
    19141 gggattacaa gtccagataa cgtggcagaa atgcttggtt ttcctaaaca gaatactcca
    19201 gaaacacaag ctatctatat ttcaaatgac ttatctagga ttggccagaa aaatgcaaca
    19261 gatgattcct taccaacgaa tgatcaagac ttgaaaggag gtgatggaaa tgaagaagaa
    19321 ggaaattcgc acgattgaca tcaccaatct ttcaacacgt tccgatgaag aaactcatac
    19381 gaggaccatt agcggctacg ctgctgtatt caacagtcaa acacttttat gggatgactt
    19441 aagcgaagtg attgttcctg gtgcattctc aaaggcaatt agtaattcgg atgttcgttg
    19501 tttgttcaat cacgattggt ccaatgtgct aggacgtact aaaagcggaa cccttcgcct
    19561 tgaagaagat gaacgtggtt tgaaattcga agttgattta ccggacacaa cggtagcaag
    19621 ggacttagtt aaatctatgg aacgaggaga catcaaccaa tgtagttttg gttttgtgcc
    19681 gactgaagaa acgtgggact acaattctga accaatgctt cgaacaatcc atgaagtgga
    19741 attatacgag gtttctattg tgcctttgcc agcatacgaa gatacagaag ctgcattaag
    19801 aagtcgtgat gaattagaaa aaaacgtcga agaaagaaaa aaattaatca aaaaaattaa
    19861 tcaagcgcta gaagcgtagg aggaaaaata catggataca gaattattga aaaaaatgaa
    19921 ggcacgtcgt gaacaacgat tgactgaatt acgtgaaaaa gttgaatcag gagaattacg
    19981 cgaagctgat ttagaagcta ttacaaaaga aattgatgcc gttgttgatg aattgaacgg
    20041 aatcaaaagt gaactaagtg aagccgatgg atcagatgaa ggttcagatg ctgacgaagg
    20101 aacaggtgga tcagacggct cgactggaag cgatgaaaat cgttctggtg aagacaacga
    20161 tcaagaagaa gattcagaca gtgaagatag ttcagaaaat cgttctggaa tgattactca
    20221 acagcaacga gatggattac ttggatcaat taagaacgga ttggaggcac gtgcaaaaat
    20281 gaccaataaa caaaaagatc aacaactacg aaaagcattt gctaattttg tagttggaaa
    20341 tatttctgaa gcagaagctc gagctttagg gattgaagct ggcaacggct cagttactgt
    20401 cccagaagta attgcatctg aagttattac ttatgctcaa gaagaaaatt tacttcgtaa
    20461 atacggaaca gtggtgcgaa catcaggaga tgtcaaatat ccaattcttg tgaataaagc
    20521 agatgcgaat gtaaacaaga aagagcgttc aactgatatt gctgaaacag ctattcagtt
    20581 tgatgaaatt ttgcttgatc ctgccgaatt cgatgctttg gcaacagtaa ctaaaaaatt
    20641 actaaaaatg tctggtgttc cagttgaaga tattgttgtg gaagaattga aaaaagctta
    20701 tgtgcgtaaa gaaatcaatt atatgttcaa tggtgatgac gctggaaatg aaaatcctgg
    20761 tgcattagcc aaaaaggctg tagcatttga aaaaccttta gatctaactg ctgcaggtgc
    20821 tgggcaaaaa ttatatgatg cattaatcga atttaaaaat acaccagtga cagaagtgat
    20881 gaaaaaggga cgctttatta ttaatcgagc tgctttgact gctattgaaa aaatgaaaac
    20941 agatgatgga tttcctttgt tgcgtccatt tacacaagca gaaggtggaa taggttacca
    21001 attagttggc tatcctgtgg attggacaga tgcagcagat aaaaagggtg aaccagacac
    21061 gccagtttta tattttggcg atttttctgc atttaaaatt caagaagtta ttggtgcctt
    21121 ggaaattcaa aaacttgttg aaaaattctc tggtaaaaat caaattggat tccaaattta
    21181 caacttgcta gatggtcaat tggtttattc tccatttgaa ccggcagtat atcgctacga
    21241 aattacaaaa ccagttggtg gttaagatgg aagagcaaac taaagaattg tctttagagg
    21301 aaaaattcaa atcacatatt cattttgaag agggcatgga tgattctttg ctctcttttt
    21361 atttaaatat ggcaaaagat tatgtcaaaa cagcaactgg tggccaacaa gaatatctta
    21421 ttttgatggt tgctggcatc gcctacgaat accgagtatc tgaagatgag ttagacaaag
    21481 ctatgaatgc catgacgcca tttatcgtgc aaggagcgat tcaaaatgcc gaagagacag
    21541 actaataatc tcagatggaa agccgaattg ctagacatca aaacaggaac agacggaaac
    21601 gatcgtccaa ctacaattta cgaatttaag cgtctaatat tctatgaaga actcggtgtg
    21661 acttctcaag aaaaatattt atcacagcaa gccaagacag acgttgtcag acgaattaaa
    21721 gtcagatggg ataaatccat cacagagaaa ttaagtgcgc tcaaaattga ttctgtaacg
    21781 tataacatta ctcgcattta tacgaatccc gatgcaagag aaatggagtt gagtttagct
    21841 tatgtcgatt agctttgatg aattgaaaac agcgctgaaa tcaacaaagt tagcagtgtt
    21901 cagagacaaa gccagattag ggacgatgta tccatacatt gtgtactcaa atgtgagtaa
    21961 cagcaaaaaa atggcatccg gtaaagtcta taaaaaatta ccttattacc aagtctcttt
    22021 ttttacactt ggaacagaac aggatttagt tgttattgaa caagcgctgc aaaatgctgg
    22081 cattccatat tcagatttta caggtataca aggtgatgag aacgacgata ccgtaaccaa
    22141 ctattacaca tatgtgaggt gtgtggaaaa tgccaagtaa taagaatggt ttttctgaaa
    22201 tatcggatta tttaggaaac ctttcaaaag ttgatccgaa aaaattatcg ttggaatctt
    22261 tagaagaagc agctaacttt tatctaaagc agttgcttcc taatattcct aagtcgctct
    22321 taaaaaagaa acatatgcgc gatcaaataa aagtagtagt tgaaaacgat caagtgaaag
    22381 ttcaatttga agagacggcc ttttactggc gctttgccga aaatggcaca acaaatcaac
    22441 gtgcccaaca ttttgcaagt ggtacgtatg aacaaaacaa agaaaaaatt gaagaaatta
    22501 tgactagaaa aatacttgat ttatgggaag ggtgatttta attgggaaaa caagatactt
    22561 tttattttga aggattggac gacattttaa ttgcgatgat ggcaacgcca gattctgttg
    22621 gaactgcacc gacttatagt gaagttttac gattgccaat tgccacaaaa atcggtgtca
    22681 aagggaatgg aacagcatta gaaaaatggg catccagcaa aatgtttcgt cgtgtgtcgc
    22741 gagaaacaaa acatgaactt gcgttggatc acgtgggtat tccgatagaa gtgatggatg
    22801 aaatcaaagg attagttgct aaaagcggag taacgtttag caaaaatacc gcacgagaat
    22861 ttccgtactt cgcctttgga tttattggaa atattgaaaa tggcggtaaa aaagcagttt
    22921 ggtatcctaa tacacaacta tccaatgtga ttgacgaaga gtatgccact gcagaggaag
    22981 aaacaaaaat tgacgatgta actgcaaatc tggtttccat cggactgaaa tacaataatg
    23041 tgatgtatgc aagttttgat tcaaatagag acggagcttc tctagaatta tttaataaat
    23101 tcattgctca acctgtatac gatgaagaac agtggaaaac attggctaaa gttggaggtg
    23161 cgggttaatg gctcggttat ctgattatgg aattcacgtt gaagacttaa aaaattctgc
    23221 tgttgtaatt attcaaggcg cagaattccc tatttcattt actatgcaaa cgatggaatt
    23281 tatagcagat gtgtatggtg gagattattc gcaatttgaa tctgatatga acgccatgct
    23341 atctaaaaaa gaaggacaaa tttcttctgc taacttatcg cctagtgatc taaaaatcat
    23401 gcgtgccttg atttatgcca tgctgcgtac tggtggttta gaggaagatc cagaaactat
    23461 tttcaaattt ttgggaatga gtggagaggt gttgtctgct tatagtacct gtatggaaat
    23521 ttttgctagc cagacatttc aggtggaaga cctaaaaaaa tccaagaagc cacaagactt
    23581 tcaaaaagcg caagcaaaaa gaaagaaaaa caaaaagaat cggaagagat aggaactcct
    23641 tggagttttt atatttacgt tgctctcact ctattgaatt ggagtgagag tttcttttta
    23701 aagtctacac ctaacttgtg gctcaaatct tatttacagt ggttacaaca aaacaccgat
    23761 tttgaaccac ctcaatctgt aactatggat aaatcgcctt ggtggtagaa aggagcgcta
    23821 agataaatgg ctggtaaaga atctgatgtc gttcttaatt ttaaaacgaa tggcgaagtc
    23881 agttattcga aaacaatcaa agaaatcaac aaagaaatga acttagccgc tgccgagtac
    23941 aaaaaccaag tgtctgcgat ggacaaggat gcaactcaaa cagaaaaatt gcgagcggct
    24001 aaacaaaaat tagaaaaaca attaggattg gctgaacaac gatctcaaat gctgagagag
    24061 gaatatgaaa aatctgtcaa agaaaccggt gaatattctg ctgaatcaga aaaactttat
    24121 aaacaattac tcaattctga aaccggagaa aataaacttc gtacagcatt agaacagacg
    24181 aacgatgcac ttaaagaaca aggtgacgtt tctgttgata cagcaaaaaa actccagaaa
    24241 atcgaagaaa caggtgagaa agtaaaaggc gttggtgaaa aaatgtctgt tggagtaacc
    24301 gcgcctattg tagcggcagg agcagcagga cttgcagcat ttggtgaagt tgacgaggca
    24361 cttgatacca tcattacaaa aaccggagca acaggtgatc aagctgatag actttcacag
    24421 tctttcaaaa acgttggttc aaatactcat ttacctttac aaacggttgg ggaagctatt
    24481 ggtgaggtaa atacacaatt tggattcatg gataaaaaac tggaagattc aaccaattat
    24541 ctcctacagt acgctgaaat caatgataca gatgtttcgc aatcagcaat atctgctcga
    24601 caagctattg atgcttatgg actagaatat gatgatttga attctgtcct tgatgtaaca
    24661 acgaaaacat cgcagaatac tggtcaatct gtagacgact tgatgcaaaa agcaattgat
    24721 ggcgcaccac aaattaaaca attagggttg agctttggtg aaggggtcac tttacttgga
    24781 caatttgagc aatctggtgt tgattcaagc gcagctttaa gtagtttatc taaagcaaca
    24841 gtggcttatg cgaaagacgg aaaatcttta agtcaaggac tagaagaact acaagacaag
    24901 gtaaaaaatg caggttctga aacagaagcc atcaatgcag cagcagaagt attcgggact
    24961 aaaggcggtc ctagaatggc cgatgcaatt cgtagaggta ctttgaacct ggaagattta
    25021 gcaaaaactg ctggagaaag tgggggagct gtaggagaca cattcgatgc tactctcgac
    25081 ccaattgatc aagccgatca agctatgaac aatgcaaaat tagcaatggc tgacgtaggt
    25141 gaagcagtcc aagtaagcct tttgcctttt tttgaaaaag caacttcctt attacaggaa
    25201 ttctctaaat ggtgggggtc tctagatcaa gatacaaaga attggatcat aacaattgct
    25261 ggtatagcgg cagcagttgg accagtacta atcgttcttg gttcgctgat gggatctgta
    25321 acaaaaatcg ttgggggagt taaaagtttt ataggagttt ggcaaggact tgctggttta
    25381 tttggaatgt ctggtggctg gtttgcatta gcagttatag ctattggcgc attagttact
    25441 ggactaattt gggcatataa taacgttaaa tggtttcatg atggagtgaa ttctttcttc
    25501 aaaggtgttt cagatgtagc tgttgaaata tttaattttt taagtggtta ttttggtgga
    25561 tttttcgatg gtgttatagc aaatttcaat aatttttata atgctggaaa acgaattttc
    25621 agtggttttc tagattttat cactggagta tttacaggga attggtcaaa agcatggcaa
    25681 ggtctagttg atatttttgg aggtattttc gatggtattg ttgctgtagg gaaagctcct
    25741 attaatgcca tgattggatt gatcaatgga tttattggtg gattgaataa tataaagata
    25801 ccaaaatggg ttcctggtgt aggtggaaaa tcattttcta tttcaaaact gccttattta
    25861 gcacaaggcg gtcatctaat caatggacaa gcgattgttg gtgaagctgg acctgagtta
    25921 ctgactgcca agaatggtaa aaccacagtt actccattat cagacgaaga aaaacgcaaa
    25981 gggatcagtg gaagagtttc tggaggtagc attgaacagc atatacacat tggcaaagtc
    26041 gatgcaaaca atccatctga gttagatcgt atgaatcgta aatttgctaa agcaaacaaa
    26101 caggctattc gtgatttggg aggtgttcct atttgagtcg acaatttatg aatccagatg
    26161 aaccaaattt tatttggaaa aatcggaatg cagtaattga tatgaattgc atcattgagg
    26221 cagagcttcc agatattatg ccgaacaagc gatacgaaac ttacacgatt cagggccgaa
    26281 gcggagaatt gacggagacg tttgatgact atgaaccttt tgatttggaa atagaaggga
    26341 tcactattcc acattcgaaa ctgagagaag tcaaacgatg gctcactggt aaaagccaat
    26401 taatcacaca taatgatcca gacaagtatc tagaggctat ctgcagcatg gataaagaag
    26461 tccctttcga aaacgagtgg ggcttctttt atacattcga tgttactttt cgttgtcagc
    26521 cactcaaaag aaaaatcggt gaagcaccta aaatttttca ttctagtgtt atggatattt
    26581 ttgatcatgg tgacgaaatt gcacatccct atctggaaat agaatcgaac ggaggagata
    26641 taacgatcgc tgtcggtgat aaaagcctaa caatacttaa tacgttagct gcaacaatcg
    26701 tggttgatac tcagcttgga aaagcaatac aagaaggttt gaatttattt acgcgtggtg
    26761 attggccagt attgcagcct gaatggaatc aggtaaaaat atccggaaaa tttaaagaag
    26821 tgcggttttg gaataggagt gtgtatctgt gacgcaagaa tttatttatg cttataaaaa
    26881 aatgccagat gatttgagcg tgaacggagc gtcgttagtt gattgggaag atttgccaga
    26941 aatcaatcgt gtgctgaatg gccaatatcg tttttatggt aactattcaa gaagcggaca
    27001 gtatcgctct tatttaaaaa aaggaaattt tataaaagcg aaggtaccag atggatcatg
    27061 gcaatatttt gaaatttata atgtcaaaaa gaatttgacc tccgtttctg taacagctcg
    27121 gcatattggt tttatggcca ataagaactt tattgtcaag tcgtttacgg ataacggcaa
    27181 tgggtctcag atcatgacca atcttaaaaa cagtttggca tttgatcaaa aatttaacta
    27241 tctttcgaat gtagggacaa cgcaccaatt tacagcaaga caagtcgcgc cagttgaagc
    27301 aatcattggt tcaaataacg gtaatcaaaa tttgactggc gtgactagcg cggaacttga
    27361 tatggataac tatgatttga aactggtaaa acagattgga tcagataatg gttttcggat
    27421 tgattttggc atcaatttag aagcaatcga agaagaaatt gatgaagaat caattgtcaa
    27481 tagtttgtat ttggttggcg gtgttcctga taacgattat gatgaagaca aagaacctat
    27541 cgaatatggt tatttagaaa ttgatggagt aaccaacgag aatcgacgta ttgccaaacg
    27601 tgaaaacgga gattgtaaaa cagttgatga attgatcaaa tggggcaaaa ccttatttga
    27661 caatgatcgt atccatgagc caaaagctac tcatacagtc agtatggtgg cgttggaaca
    27721 cacactcgaa tacggtgaca tgtatcaaga gctagcgtct ttacactttg gtgatgtcgc
    27781 tcatgttagg gcgaaagagc tagatatcga gataaaagag cgtatggtcg aatacactta
    27841 tttcccaacg cttgggaaat ataaggatat tgttttaggt aatgatttat cactgtacac
    27901 ttcggcagta aatactcaag cacaagaatt gaaaaagaaa atcgacaatc gaacagaaac
    27961 gttagttcaa aatgtgttga atgcgacggc atggatcact ggtaattctg gtgggcatgt
    28021 cgtttttcgt ccagaaaaag ctccatcaga gattcttatc atggatactc caaatgtggc
    28081 gaatgcaaag cgagtgtggc gttggaattt aaatggctta ggttattcag acaacggagt
    28141 aaatggcccg ttcggtattg ctatcacatc aaaaggagaa attgttgctg acttcatcaa
    28201 agtaggaaca ataaatgcag aagtattcga aacttccttt aatgcttatg gtgatgtgtt
    28261 aaaacttgta aaaggcacgc ttcaaatttg gaatgaaaac aaaaaaatca tggagctaac
    28321 caaaaaaggt atggaattct ggaatagaaa agaatccatt ggaacgatcg gaacaacaga
    28381 ttcagcagga aatccatttc caaatgctgt aacacctaca cctcttgagg aaaattcttt
    28441 ggtaatacgt acaaatggcg atggaaaata cattttaatt tctccaactg cagaaaaagg
    28501 atttgtgtta ttaggaaacg gaaaagcata ttatttcggt gatttagata ttcagggaaa
    28561 acttactgtt agaggtaaag aagtgatacc aggacaaaat ggcggtccat ctggcggagg
    28621 agaaacacct ggtgggtatc ctgatgaatt aaaaacagat gcagaaaaga gagcttggag
    28681 aat
//
LOCUS       DACBZK010000032        27753 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.032, whole genome shotgun sequence.
ACCESSION   DACBZK010000032 DACBZK010000000
VERSION     DACBZK010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27753
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.032"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            6..623
                     /locus_tag="IVD66_001471"
     CDS             6..623
                     /locus_tag="IVD66_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145699.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCGEMKID"
     gene            1643..2812
                     /locus_tag="IVD66_001472"
     CDS             1643..2812
                     /locus_tag="IVD66_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP6145700.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            3285..3839
                     /locus_tag="IVD66_001473"
     CDS             3285..3839
                     /locus_tag="IVD66_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP6145701.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(4012..4485)
                     /locus_tag="IVD66_001474"
     CDS             complement(4012..4485)
                     /locus_tag="IVD66_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP6145702.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            4497..5033
                     /locus_tag="IVD66_001475"
     CDS             4497..5033
                     /locus_tag="IVD66_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP6145703.1"
                     /translation="MPARIHHISIVNRFIRPTFDFYHNILGLKLLMKTINQDDHTMYH
                     LFFSDNHHRVGTELTFFEVQEGNNQFFGTNTIERTILKVPSEASLHFWEIYFETQGVC
                     HYGIESFSGRPILRFEGPDATRLALVPLREFEDIDDYFPYVTDQIPTEHAILGIDAIQ
                     LRVQYSDATERELLSVGW"
     gene            5073..5444
                     /locus_tag="IVD66_001476"
     CDS             5073..5444
                     /locus_tag="IVD66_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP6145704.1"
                     /translation="MTILDNQDTQFYQEVQIIQDRENPVAIEGIGSVHHVAFGVENKS
                     DLQRIDKQLQERNFINSGIKDREFFVSLYYRDPNQLLIEIATGEGNLDAKAYENQSPR
                     FEEIPLFLPQYLNFIREQVEQ"
     gene            5728..6999
                     /locus_tag="IVD66_001477"
     CDS             5728..6999
                     /locus_tag="IVD66_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HAP6145705.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            7244..8269
                     /locus_tag="IVD66_001478"
     CDS             7244..8269
                     /locus_tag="IVD66_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6145706.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            8563..9672
                     /locus_tag="IVD66_001479"
     CDS             8563..9672
                     /locus_tag="IVD66_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP6145707.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            9755..10651
                     /locus_tag="IVD66_001480"
                     /pseudo
     CDS             9755..10651
                     /locus_tag="IVD66_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008378728.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            10667..11491
                     /locus_tag="IVD66_001481"
     CDS             10667..11491
                     /locus_tag="IVD66_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002579255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6145708.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            11523..12833
                     /locus_tag="IVD66_001482"
     CDS             11523..12833
                     /locus_tag="IVD66_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HAP6145709.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            12981..14240
                     /locus_tag="IVD66_001483"
     CDS             12981..14240
                     /locus_tag="IVD66_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP6145710.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            14250..15122
                     /locus_tag="IVD66_001484"
     CDS             14250..15122
                     /locus_tag="IVD66_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6145711.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            15134..15964
                     /locus_tag="IVD66_001485"
     CDS             15134..15964
                     /locus_tag="IVD66_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6145712.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            16004..18187
                     /locus_tag="IVD66_001486"
     CDS             16004..18187
                     /locus_tag="IVD66_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAP6145713.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            18248..19468
                     /locus_tag="IVD66_001487"
     CDS             18248..19468
                     /locus_tag="IVD66_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HAP6145714.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            19465..20925
                     /gene="gtfA"
                     /locus_tag="IVD66_001488"
     CDS             19465..20925
                     /gene="gtfA"
                     /locus_tag="IVD66_001488"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HAP6145715.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            21002..22108
                     /locus_tag="IVD66_001489"
                     /pseudo
     CDS             21002..22108
                     /locus_tag="IVD66_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            22430..22639
                     /locus_tag="IVD66_001490"
     CDS             22430..22639
                     /locus_tag="IVD66_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP6145716.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            22632..22781
                     /locus_tag="IVD66_001491"
     CDS             22632..22781
                     /locus_tag="IVD66_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HAP6145717.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            22816..23600
                     /locus_tag="IVD66_001492"
                     /pseudo
     CDS             22816..23600
                     /locus_tag="IVD66_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922412.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(23884..24969)
                     /gene="xerS"
                     /locus_tag="IVD66_001493"
     CDS             complement(23884..24969)
                     /gene="xerS"
                     /locus_tag="IVD66_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HAP6145718.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            25303..25536
                     /locus_tag="IVD66_001494"
     CDS             25303..25536
                     /locus_tag="IVD66_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HAP6145719.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            25533..25940
                     /locus_tag="IVD66_001495"
     CDS             25533..25940
                     /locus_tag="IVD66_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAP6145720.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(27077..27595)
                     /locus_tag="IVD66_001496"
     CDS             complement(27077..27595)
                     /locus_tag="IVD66_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HAP6145721.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         9530 a         4173 c         5107 g         8943 t
ORIGIN      
        1 gaaccttggg ttttcaagtg ctttttggtt cattaatctt aaccatagtg tttttaaagt
       61 ggaaaacaag caacaaaaaa agtatgtgga gccttgtagg aatagttctt attattttta
      121 ctgtgactgc agcaacagaa gcaaattatt cgcataaaat tcagtcgtat aaaggtcgtt
      181 tagttatgac caaaaaagat gttacacgtt atacatcctc aagaactgga ggcctatatg
      241 actatgcacc attagatgca ttgaaatata aagatcattt aaagaaacat gaagtaaaag
      301 ttggtgatcg gtgggagaat gcatctcata aagcatataa ttccaaaata gtctatacag
      361 tagaagatgc cgatgagcaa aatatcacat tacctgtatt caattattgg ggaacagttg
      421 tgaaagtaaa tgggaaaaag agcactatag aaaatgacaa tggtttagtg tctattaaag
      481 gtacggggaa aagaactata gttgaggttt catctacgta tccaactacg atgattctat
      541 ctttattaat tagttcaata acttttatat tcttatttac acgttattta ataagatgct
      601 gcggtgaaat gaaaatagat tagatagata ttataaatat gttgattcta ttttcatagc
      661 aatggagaaa atacattagc aatatataaa agaaggtatc aagagtcaca gtgaatttat
      721 tccgaaaagt gaaaagagca aatataaaat ttaatgaaaa tatagaacta aataggaaaa
      781 cgtagacgta attttctacg ttttcctttt catatatatt aaatattacg gaaaattata
      841 taaactaatt tagtgttttg tttgtaattc ctaattttgc tccactttta gataattttt
      901 aggtctattt aactcatcag acattctatg ctcatttttc tccaaatttg tttcaactct
      961 ttcgtactta attttgcgta tttgaaaatt cttcttttag agtactttta ttacgatact
     1021 agtatgatat atatctatag caaacagtta aaatcttcct aaaataagcg aatagcattc
     1081 ctaaaaccta taaaattttt agatgaagcg acaagtggac aattaataaa ctacttgaac
     1141 atgaaattat ggatcacctt tcaaatttag aaaatggaat tcttatactt attgcgcaac
     1201 atttattgat tgcaaaatta tgtgacaaaa aaaactagta gaagaaagaa taatggcttg
     1261 ataataaagt actacctatt aaaggtagta ctttatttaa tttagtataa attaacatac
     1321 tactatattt taggtttcat attatataaa ttaataatat actaccattt gttggtagta
     1381 taatttaaag gtaataagtt attcttttat tactatgttt gggttttata gcaaagaaag
     1441 tttaataaga gtttggacct agcaaacaat attaatgagg tcattaaatc ttattatctt
     1501 tagtgatata acgaaatatc tacacagaca aaatgatagc gtaaaatatt ttgtgtaaat
     1561 agatatttag ggtagaaaaa aagaaagtcc attctgtaaa attaaagtta ccacaaccga
     1621 aattttatag gaggactttc tcatgcccaa ttttactaca gaaattatgg aaacactaat
     1681 caataaaggt gatttagatg aattatttcg atgtcattta gaattagctg ttaattcatt
     1741 attgcaggct gaattaacag cttttcttga ttatgaaaaa tatgatcgtg ctgggttcaa
     1801 ttcaggtaat tcccgtaatg ggaattattc acgttcattc agaacagagt atggagaatt
     1861 aaatttggta attcctagag atagaaatgg taagttttct caacaaactt tacctgctta
     1921 taaaagaacc aatgactctt tagaaaccac tattattcag ctatttcaaa aaggaattac
     1981 tatgtctgaa atctctgaat tgattgaaaa aatgtacggg catcactata cgccacaaac
     2041 catttcaaat atgactaaaa tagtttctga agatattatt gcctttaaag aaaggtcctt
     2101 agaatccaga tactctgtca tttttatgga tgctactcac attcctttaa aaagacaaac
     2161 tgtttcaaaa gaagcagttt atattgtaat tggcattcga ttagatggaa ccaaagaggt
     2221 tcttgggttt agtcttgctc caactgaatc tgcttatgtt tggaaagaga ttcttcaaga
     2281 cctaaaagac cgtggtttaa aagaggtttt attagtcgta actgatggtt taagtggcat
     2341 taacgatagt attcatagtg tttatccaaa tgctcaattt caacaatgtt gtgtccatat
     2401 atctagaaat atcgctcata aggttcgtgt tagtgatcga caagaaatct gtagcgattt
     2461 caaattagtt tatcaagcaa gttcaaaaga agaagcaaat aatcaaataa ggtttatgat
     2521 agataaatgg aaaaagcagt atccacgagt ggttaaattg ctcatgaatc ctgctatatt
     2581 aaccttttat aatttccctc cgtcaatcag aagaactatt tattcaacta atttgattga
     2641 aggttttaac aaacaattaa agaaatatac caaaagaaaa gagcaatttc ctaatgaaga
     2701 atctctggag agatttctag tatctcaatt caacaactat aatcaaaagt ttctatgccg
     2761 agttcataaa ggttttaaag aaatacatga tacattagaa tcaatgtttt aacttgatca
     2821 acagaatggg cttttccatt tacacaaaat tattgacgct cccgacaaaa ttatgatctt
     2881 gcgtaaagtt ataaaatatt aataaaaata ttttattaat gaaaagcttg gtagcacggt
     2941 tattcatatg ctaatttatt tcactttata gtaaggggag ttcttagtat attgttcaaa
     3001 cttaaatttc atataattta attatgtaaa ttagctattc taagaacttc tacggataac
     3061 tgcccgtcta aaatttaaat aagagcttag aatcttcata taagtaaggt taattttttt
     3121 gtacaaaaaa gtcggaatat tctgagttac tgaaatgata taaaatcata aactaaaccc
     3181 cttgattttc ttcactttta acagagtata tatataagtt catgattatg gtaaaatata
     3241 tacataatca ttaactcaga atatttttaa gaagggaaac aatagtgagc tataatgtac
     3301 aaccgttaag gacaaatgaa gagatacaag attttcagtt ttggctaaga agaacaagta
     3361 atccggaaag agatagtttt ttatttttgt ttggaatcaa taatgggtta cgtatgtcag
     3421 atattatagg attaaaagtt ggagatatac gaggcaaaag taagcctatt attgttgaac
     3481 ataaaacagg taagcgaaaa ccgattttta tagataattt gagagaagaa attttattat
     3541 atactgaagg taaagaagaa aatgattggt tatttccgag tcggcaacaa ggtcgacata
     3601 taacaaggga tcgtgtctat cagatatatg cagatatagc agaaaaatta ggacgagatg
     3661 atataggaac acatacatta agaaaaactt ttgggtatca ctactacaag aaaactagag
     3721 acattgctac cttaatgttt atttttaatc atagctcgca agcaattaca aaaaggtaca
     3781 ttggtataac tgaagatgaa ataggagcat cacttcgtgg atttaaacta ggtgtataat
     3841 ttaaaaattt ttataaacag taaagacaaa gattaaaagc tatttttatc tagaacgatt
     3901 ttatttcata aagttcgcgg aataaaagct ggggttactg gtacttggta taggttcgtg
     3961 ttatataaac taagtaatta aataacattt ttaggttgga aaaggatgaa attaaaaaaa
     4021 gagaatcaat acggtctcaa aaacgcaaac gctgcggaat aagaaaaata ctgataactc
     4081 aacgtttagc agactatcta atagggatag tctgcttttt tcgtttttga ccatactttt
     4141 gaccttctgc aaacttcctt gcttttcctc tgtagaactc atgaaatctg caaaacgaat
     4201 tgccgtttcc tctgtctgct ttttcgcgat atgggtgtat atatcatcca tagtggtttt
     4261 aatatctgta tgtccaagtc gaacatacac ttctttgaca gacgcaccag attcaaagag
     4321 cagactacaa tgggtatgac gaaaaccatg aagtgtgata tgttttaagt tattctcttt
     4381 aatgatgatt ttcaaattgt gatttacata gtctaaataa aggggcttat tttcttctga
     4441 tgaaaacaaa agttgttcac catcttttat aggtttgatt ctcattttta gatattatgc
     4501 ccgcacgtat tcatcacatt tctattgtga atcgctttat tcgaccgaca tttgactttt
     4561 atcataatat actcggttta aaattactaa tgaaaacaat taatcaagac gatcatacca
     4621 tgtatcacct gtttttttca gataatcacc accgtgtggg aactgaactg actttttttg
     4681 aagtacaaga agggaacaac cagttttttg gaaccaatac gattgaacga acgatactaa
     4741 aagttccttc cgaagcatca ttgcattttt gggaaatata ttttgaaaca caaggcgttt
     4801 gccattatgg aatcgaatca ttttctggac gacctatctt acgttttgaa gggccagatg
     4861 caacacgatt agctttagtt cccttacgcg aatttgaaga tattgatgat tatttcccgt
     4921 atgtcacaga ccagatccct acagagcatg ccattttagg aattgatgcc attcaactac
     4981 gcgtacaata ttccgatgcg actgaacgag agttattgtc ggtaggctgg tagcacaaag
     5041 aatacgtcag tttcttttcg ggtcatcaac gagtgacaat cttagataat caagacactc
     5101 agttctatca agaagttcag attattcaag atcgtgagaa tccagttgcc attgaaggga
     5161 ttggtagcgt ccatcatgtt gcgtttggcg tagaaaataa atctgattta caacgcatcg
     5221 acaaacaatt acaagagcgc aattttataa attcaggaat aaaagatcgt gaattttttg
     5281 tatcacttta ttatcgtgac ccaaatcaat tattgattga aattgctaca ggggaaggaa
     5341 acctagatgc aaaagcgtat gaaaatcaaa gtccacgctt tgaagaaatt cctttatttt
     5401 taccgcagta cttaaatttc attcgtgaac aagtggagca ataattagct aatcaaatcc
     5461 atgacgaaga gtaagaggtt gactcataag tcaaaaaata aagaaaaacg catcaaatcc
     5521 attctaaaga atgttgattt gatgcggttc ctatttttat aaactatcat tttcgactaa
     5581 taaaactact tatgagtcag cctctctttt tttcttgatt tttatacctc tttctaggta
     5641 aactaaacat ctgccaaaaa taccgtgtct cattgaaaca ttctcaacta tttcaaaata
     5701 aaggggagta ccaaatgaac gagtatattg aaattatcca cgcaagagaa acaacttaaa
     5761 aatgtcagtc tcaaaattcc caaaaataaa attagtattt ttaccagcgt atctggttca
     5821 ggaaaatcat cgattgtttt tgatactatt acccaagaag ctggtcgtca actgaatgac
     5881 acctatgata gttttacccg tttattttta cctaaataca gtcgtccaga ggttgatgag
     5941 attgataatc tttctacggc gattgtggtc aatcaaaaga agattggtgg cagtgcgcgc
     6001 tcaacgttag ggacgattac taacatcaat gcgttatttc gtgtgttgtt ttcatgtttt
     6061 gcaacaccta gtttaggata tgcaaatgct tattcattta atgatcctag tggaatgtgt
     6121 tctgtctgtc agggaatcgg taagacgatt gcatttttaa taggattgct ttatttttcg
     6181 gctattgata atgctgattt tgtattttct gatccattta ccgcagaagt tttgtctgga
     6241 attgaggaac aggcaaagaa tcatggttat tttgtattgg tgcataatgt taattcagca
     6301 gaagatgtta aaactattca gagaaattgg cgttttgagg ggttcattgt tgttggtgta
     6361 cgtgtaaaag aatttttgga attaaataac gtttttgatg gtcctgttgt ttatattgat
     6421 acgcatcttt caaaagagac attaagagaa cttgaacaac aaatgaatcg tttatttgta
     6481 aatacaaatg attaccaagc tagtacattg gcagtggaac atttgattca ttatggtcat
     6541 gagaaaatag cgtttctttc ttttgactac attgtaggtg aaccaagtgt tattcaagaa
     6601 cgacatcaag cttatatcga tacattaaag aaatatcatt taacctttaa atcgcattgg
     6661 atatataaca actctgaatt tgagcgaatt tatcaagaat tagctgaatt tactgcaatt
     6721 gttgttactg gagattattt agcggctaaa ttagtaaaat ttttaaaaaa taagaataaa
     6781 cgagtgatgg aacaattatc gattattgga tttgatgata ttacttttgc agaattaatg
     6841 gatcctgcgt tgacaacaat acgactaaat ccaggtaaca agggggcgat tgcttttcac
     6901 caactgattg gactggccaa acaagaagaa ataaaaaatc aagtactact attagaggga
     6961 gaattgattt ctcgagactc tgttcacaaa atcaaataaa aaagctctgt gaaataagta
     7021 tagttaacaa taaaatatcc gaacgataga gagaatgaac tgtgatctag cagttcctcg
     7081 tcgcaaattc actagaatta gcattattta ctctaaattg ttcggatatt ttttcttgtt
     7141 tttaattatg attacagtgc ctatttttaa cgaaatttgc ttattttcaa aatgtatgat
     7201 tatatgttag taaacacttt caaatatgaa aagaggagct attatggtag gaattaggga
     7261 tgttgcaaaa cgggcgggtg tgtccattgc aacagtatcg cgcgtgctaa atgaggatcc
     7321 gacactttca gtaaccgatg aaaccaaacg aaagattgca gaatcggtta atttttatca
     7381 ttatgtcaaa aaaagtcccg ttgcaaaaaa tttaacaaat attgcattaa taacgacagt
     7441 ttctgaagta gatgagttgg aagatcccta ttttcgaacg attcgcagag ggattcaagt
     7501 cgaagcagaa caaagcaaag tcaatttgaa gaaaattatt cgtttgtcag aaacaccgtt
     7561 ggagcaagac gatttgctaa aatgtcaagg tgtgttgatt attgggcagg tgctatcttc
     7621 tgtgattgaa gaagtatcag caattaattc gaatgtcgta gtgattgatg accctagtat
     7681 tgaagctgaa gtagatgcag tttatactga tttaacaaaa gcaacgaatc agcatttaga
     7741 tcgattgtat aaaaaaggac accgaaacat tgcgtttatc ggaggaggac gtgttcgttt
     7801 agatagccaa ggaaataaac acgtgtcaga tgatgattat cgaaaaatag cctatgagac
     7861 gtggatgaaa caaaaaggat tagaaaaata tagtcaaatt tatttagaag gctggaccac
     7921 acttgacgga atgcaggcag cagatttact tttgaaaaaa catgctaaag ataagttgcc
     7981 gactgctatc atggtaggaa atgatcctat tgctgtgggg gtttatcgtt cacttcaaaa
     8041 aaatggtcta catattccag aagatatttc gattgtgagt tttgataata ttgaagttgc
     8101 tgaattttta acacctgcat taaatacggt gaatgtgaat acagaagaaa ttggaaaact
     8161 agcagttcgc atggttaatg aacgaataaa agaagttaga aatgtttcga tcaaagtgat
     8221 tgtttctaat aatattattg ttagagaaag tgaaaaaaat atcgattaaa aaagtaaaca
     8281 tccaaaaaag ggtgtttact tttttgttta ctaatatttt tagtaaaaaa tctcgacaaa
     8341 acattaagta aacagttatg gtgttgttaa caaaaagaaa acgcattcaa aacaggagga
     8401 attaagatga aacatttcaa aaaaatagct ttaacaggga tagctgtttt aactgggaca
     8461 ttactcgcag catgtggtgg gggagatagt aattctaaag acgggcaagt aactttaagc
     8521 tatgcgagtt gagatactga ccaagctcca ggactaagaa aaatgttaga tgaatttgaa
     8581 aaacaaaatc ctgatatcaa agtagaaatg gagacaacgc cttgggatca atattgggtt
     8641 aaattagaag ctgcaacaac gggaggtaat atgccagatg tagtaaccat gcactctagc
     8701 gaatcctata aatatatgtc acagaatgct ttgatgggac ttgatgatgt tatcaaagaa
     8761 aatgatattg acatgggaaa ctttactgaa ggaattgctg atttctatac gcttgaagac
     8821 gaactatacg caatccctaa agatgcttct gtagtggggc tatggtacaa caaagaatta
     8881 tttgataatg caggtgtcga ttatccagat gaaacatgga catgggaaac actcagacaa
     8941 gctgcaattg atttaacaga tgaatcaaaa ggcatctatg gttttgcatc acatattgga
     9001 acagagactg gctactggcc atttatttat caaaatgggg gagaagtatt tgccgatgac
     9061 aatacaaaat caggtttgaa taccccagaa gcacaagaag ctttagcttt ttatcgagat
     9121 attgcacttg ttgatcatgc ttcaccaaca attacagaat tacaagatcc tgataagtta
     9181 agtcgttttc aatcaggtag attagcaatg atgattgaag gaaactggtt tgcaccggga
     9241 tttttgaaaa atgactatct agttgaaaat gttgcttctg ccgtgttacc taagggaaaa
     9301 gttaatgcaa caattacaaa tggacttggt tgggctgcca gtgcgagtac aaaataccca
     9361 gaagaagtga aaaaactaat ggcattttta gctagtgagg acgccaataa aatccaagcg
     9421 gaaacggggg catcaatccc agcactaaaa ggctttgaag acgagtgggc tgcttcttca
     9481 gatacaattg atttgagtgc ttttggaaaa atgttggagt atggagtccc tcgtccatac
     9541 aataaagatg gattacgagc tgaacaagca gaagttcaaa ttattaaccg tattctgtct
     9601 ggtgaagtaa ctgttgaaga tggaaccgct caaattgaaa aagaagtcaa tgcgatattg
     9661 agcggaaatt aaattagtta attatacaat atacaggcga aaggattcta tttcgtctgt
     9721 atattaatgg atgaatacca aaaaggggga tattatgaaa aatcgaattt ttggaaaata
     9781 tcgtaaagat caagtgatat ggggctatat ttttattttt ccaacggcat taggattaat
     9841 tttattaaat atatggccag caattcaaac agcaatttta agttttcaaa aaacggtagg
     9901 gttcggtgat actgaatggg tcggattaag aaattaccaa aaaatgtttg cagacggtga
     9961 agtttttcag tctttattaa acacattaat ttatgcagtg gtttcgatac ctagtattgt
    10021 tgtattatcc ttgttggtgg cagttttaat gaatagaaaa gttaaaggat tgtcgattta
    10081 tcggacaatt tattttctac cagtcgttgc tgcaccatcc gcagtcgcaa tgatttggcg
    10141 ctggatgttc aataatgatt atggactgat taataacatg ttggctaaaa taggtctcga
    10201 tggaccagca tggttaacgg atccatcgat tgcgatttat tctattatca ttgtaggagt
    10261 ttggagtgct attggttata acatggtgtt attactagcc ggcttataag aaattcctaa
    10321 agattattat gaagcagcgg aaattgatgg tgctagtcca atccagcagt ttttcaacat
    10381 tacgttacca ttagttacac caacattatt ttttgtagtt gtaacaacag ttatcaatgc
    10441 tttccaagta tttgatgtta tttttatgat gattactcct aatagtaccg ccatgtttaa
    10501 atcacaatca ttagcctatt tattctataa acattcattt attttaaatg acaagggata
    10561 tggttcggca atcgttatgt tccttttagt gattatatta attattactg caattcaaat
    10621 gaagttgcag aaaaagtggg taaactatta aggaggctat caaattatga aaaataaatt
    10681 tttttcaaat gcgccaatcc atatcatgct tattttaggt ggtattgcaa tggcattacc
    10741 ttttatttgg atgattttaa cttcagggaa aacgttggtt gaatctaccc aaattccacc
    10801 tacaattttc cctgagaaat ttcagctaag taactatcaa caagtacttg atttattacc
    10861 attcatggct ttttatatca atacattttt aatggttgtt ggacgagtga ttggctcggt
    10921 tttattttca gcaatggctg catatgcttg tgcgcgtcta agttttccag ggaaaaatat
    10981 ccttttcagc ttagtactta ttcaaatgat gattcccggt tccattttta ttactccaca
    11041 gtatttatta gcacaaaaat tgggtatttt aaatacaatt ccagcattaa tattaccagg
    11101 ggtagttagt gcgtttggta cgtttttatt aagacaattt ttcttaggtt tacctgatga
    11161 attggaggaa gcggcctatt tagaaggtgc caatatttgg acgatctttt tcaaaattat
    11221 gttgccgctt gctaaatcag gattggttgc acttggaata ttcacagcgt tgtttgcatt
    11281 taaagattta atgtggccat tgattgtcaa tacttcaatt gataagatgc ctttagctcc
    11341 gggattagca aacttacaag gacaatatgc cacgaacttc ccacaattaa tggcaggttc
    11401 gttattagca atttggccaa tagttgtgat attcatcgtt ttccaaagaa aattcattga
    11461 aggaattgct acaacaggta gtaaattata aaactattaa ttagtgattg gagagtaagt
    11521 acatgacaaa aattacattt attggtgcag gaagtactat ttttgcaaaa aacgtattag
    11581 gcgatgcgat gttaactcca agtctacaag atgcacatat tgcattgtac gatattgatg
    11641 aaaaacgact aaaagaatca aatttaatgc ttaaaaatat taataaaaat tcgaatgaaa
    11701 atcgtgctga tattgtttct tattatgatc gcaaagaagc gttaagagag gctgattttg
    11761 ttatcaatgc tattcaagtg ggtggttata aaccttcaac agtgattgat tttgatattc
    11821 ctaaaaaata tgggttgcga caaactattg gtgacaccat ggggattggt gggattttta
    11881 gaaccctacg gacactacca gtaatgttag actttgctaa agaaatggaa gaagtttgtc
    11941 caaatgcttg gttattgaac tatacaaatc cgatggcgat gttaaccatg ggtgttttaa
    12001 aagcgacgag tattaagact gttggtttat gtcatagcgt tcaagtatgc gtaccagaat
    12061 tgtttgagca tttaggaata gccgatcaat atgacttaaa tgactttcaa tggaaaattg
    12121 caggcattaa tcatatggca ttcttgttgg aaattacaaa aaatggggaa gatttctatc
    12181 caacaattcg tcagttagct gcagaaaaac caaatccaca tccagattct gtacgttttg
    12241 aattgttgaa acgttttggt tactatatta cagaatcaag tgaacacaat gcagaatacc
    12301 atccatactt tattaaatca aaatacccag aattgattga cgaattaggg attccgttgg
    12361 atgaatactt acgtcgttgt gaacaacaaa ttaatgattg ggaaagcatg cgagaggaca
    12421 ttgtaaataa tggggagtta acacatacga gaagccgtga atatgcttca tatatcatgg
    12481 attctattac gacaggaact ccgtcagtga ttgcaggaaa tgtcttaaat aaaggcttaa
    12541 tcacaaactt accgacagat gtttgtgtgg aagtaccttg tttagtcgat aaaaatggcg
    12601 tgcaaccaac ctatgtcggt gaattgccaa cacaattagc tgctttaaat cggacgaata
    12661 tcaatgttca agaactgaca gtagaagccg ctttaacact agataaatca aaaatttatc
    12721 aagcagcgta tttagatcca catctatcat ctgaattgtc tttaacagat atcaaaaatt
    12781 tagtggatga tttaatcgaa gcacatgggg actatttacc tgaatataat taaaaagaag
    12841 ctgaaagagt aaggaatttt caattcctta ctcttttctt agttaaattt agtaaaaata
    12901 ttgacaaaac acttagtaaa cagttacatt agtgttaaca aaaagaaaac gcattcaaat
    12961 tgtataagga ggagcataaa atgaagtggt ctaaaaaaat tattttagct tgtatagcac
    13021 taggagcaac gatctctttg actgcttgtg gaaaaaatca ggaagatgca agcggtaagg
    13081 tagaaataga gttttttaat caaaaaaaag aaatgactca aacgattcag gagattgcta
    13141 aagattttga agcaaaaaac cctgatattc atgtaaaagt tgtggatgta ccgaatgctg
    13201 gtgaagtaat taaaacacgt atgcttgcag gcgatgtacc agatgtcatt aatctttatc
    13261 ctcaaagtat agaattgaaa gaatgggcga aagctggtta tttagaggac ttaaccgaag
    13321 aaccgtattt agagaatatc aaaaatggat atgcacaacg ttttgctatt gaggatcgtg
    13381 tatatagcat accattaacc gctaatgtct atggttttta ctataacaaa actgcttttg
    13441 aggaaatggg gattcaagca ccagaaactt gggcagaatt tgaaaaaata gtagctgaga
    13501 ttaaagatca aaacaaagta ccgtttgcga ttgcaggagc agaaggctgg actttaaatg
    13561 gttatcacca actagctata gcgactgctg ctggtggtga agaggaagcg aacaatgttt
    13621 ggcgtttctc agaagttaat ggaattaatg ctgaaagcaa agaaatgcaa aaagatttta
    13681 atcgattaga tttgttaaga gaaccaaaag ctttgcaaaa caactggcaa ggtgccggtt
    13741 ataacgatac agtagttact tttacaaaag gtgatgcgtt gattatgccg aatggttcat
    13801 gggcaatgcc gatgattcat tcacaaaatc cagattttga agtaggaact tttccttttc
    13861 cagcagatga agcaggtcaa agtctaacga ttggcgcagg agacctagcc ttatcagttt
    13921 ctgcaacttc tcaacataaa gaagaagcca aacgttttgt agaatatatg acaacacctg
    13981 aagcgatgca gaaatattat gatgtagatg gtgcaccgtg tgctgttgag ggcgttatcg
    14041 agaatactca ggattcacca ttaagtggtt taactgaact tgcttttact gatcgtcatt
    14101 tagtttggtt agccaaagat tggaatagtg aaaatgattt ttatacctta acaacaaatt
    14161 atttacacaa tggcaatcaa aaagccatga ttaacgcatt aaatgctttc tttaatccaa
    14221 tgaaagctga cggaaggtag gaaaataaaa tgaaaataaa agaaatttta aatcgttact
    14281 gggcaatcat ttttgtagca attccaatta ttttgcagat gatttttttc tactttccaa
    14341 tggttcaagg tgctttttac agtttaacta attggactgg tctgacttat aattttgatt
    14401 ttgtgggttt gaacaattat aagattcttt tttctgatcc gaagtttatc aaatcgattg
    14461 gcttcacttt aattgtgacg ctttgcatga ttgctggaca aattggtttt ggtattttga
    14521 ttgcgcgggc gttgaacgca aatattaaag ggaaaacatt ctttagagca tggttctttt
    14581 ttccagcggt cttatcgggc gtggttgttt ctttagtatt taaacaaatt tttaactatg
    14641 gtttaccaaa aattggtagt atgttaggca ttgaattttt acaaaccagt cttttaggaa
    14701 caacatgggg agcgattttt gcagtaattt ttgttttact ttggcaagga attgccatgc
    14761 cagtcatcat tttcttagcg ggttttcaaa gtattccaca agaaattatt gaagctgcta
    14821 gaatggatgg ggcgaatgat aagcaaattt tttggaatat tgaaatcacc tacttattac
    14881 caagtatttc aatggtattt attatggcat taaaaggtgg cttaacagca tttgatcaaa
    14941 tttttgcttt aactggtggt ggaccaagcg atgccacaac atctttgggg ttacttgttt
    15001 ataattatgc ttttaaaaac aatcagtttg gttatgcgaa tgctattgct ttagtcttat
    15061 ttatcttaat tgggattgtt tcactggcac aattaaaatt atcgaaaaaa tttgaaatct
    15121 aggaggtttc ccaatgaaaa catcaaaaga aaaaaatatt tctaaatact tgcttttatt
    15181 attagggggc ttcatgattt tagttccctt agtttcaacg ctattcggtt catttaaaac
    15241 aacacccgat attatgaata atttctttcg ttttcctaat ccagcgactt tggaaaattt
    15301 ccgaagattg ttagcggatg gaattggtca ttacttttgg aattcggcaa tcatcacaat
    15361 cattgcagta gttgctgtga cagcaattat tcctatggct gcttattcac tagcaagaaa
    15421 aatgactcgt gggaaagcat acggattgat gtatttattt ttaattttag gaatttttgt
    15481 tcctttccaa gtaattatga ttccgattac cgttatgatg agtaaaattg gtttagcaaa
    15541 tatgtgggga ttaatcttac tctatctcac ttatgccgta ccacagacac tatttttata
    15601 tgttggtttt attaaactaa atgtgcctat cagtctggat gaggctgctg aaattgatgg
    15661 ggctagtcac tttacaactt atttcaaaat tgttttccca atgttaaaac caatgcatgc
    15721 gacgactatt attcttaatg ctctatggtt ttggaatgat ttcatgctac cattattaat
    15781 tttaaatcgt gattctaata tgtggacact accattgttt caatataatt atacgggaca
    15841 atattttaac gactatggtc caagttttgc ttcctataca gtaggaattg tcacgattac
    15901 actagtttat cttgctttcc aaagaagtat tatagctgga atgagcaatg gagcagtgaa
    15961 ataaccaata aattattctc attataaagg agttcataaa cttatgatta tatttgacaa
    16021 tcacacacaa acatttcatt tacaaaataa aaaaattagc tatctattag gaatcgaaga
    16081 aaataattat ttaacgcatc tttattttgg aaaaaagatt acgcactatt ctggtgggta
    16141 tcgctacccc cgaacagatc gttccttctc acccaacaat gcaaatgcgc aagatcgttt
    16201 attatcttta gacacattac cattagaatt tccaggatat ggacatggtg attttagaga
    16261 accggcgcat aatattaaat taggaaacgg tagtcgtgta aatgattttc gttatgatag
    16321 ctacgaaatt caaaaaggaa agcccagctt agcgggattg ccagccttat atacggaaga
    16381 tgatgatgaa gctgaaacgc tgattattca attgaaagac gcgattagtg gattgacttt
    16441 acagttgttc tacacaattt atcaaaatca cagtgtaatt attcgttcta cgcaattagt
    16501 aaataatagt gatgaaacag tggagattaa ccgcttagct agtcaatcaa ttgattttcc
    16561 aaatcgtcca ctcgagttaa ttcatttaaa tggtacctgg gcaagagaac gtcaaatgac
    16621 tagagaaaaa attcatacag ggataaaagt attagatagt aaacgcggat caagcagcca
    16681 tcaacaaaat ccgtttgttg ctttagtaga tgccaaaaca gatgaatttc aaggagaggc
    16741 atatggattt aatttagttt atagcggtaa tcacgaaacg gtgattcaaa aagatccatt
    16801 tgaccaaaca cgggtcatta tgggaattaa ttcatttaat tttggttggc aactaaaaac
    16861 tggcgactca tttcaaacgc cagaagtcgt gatggtttat agtaatgaag gtctgaatac
    16921 gttatcacag acgtatcatg aattgtataa tcaccgttta attcgtggaa actatcgttt
    16981 aaaagaacgt cccacgttaa tcaacaactg ggaagcaacg tattttgatt ttaacgaaga
    17041 aaaaatcatg aatattgtcg atgatgcgaa gaacttgggc attgaaatgt ttgttttaga
    17101 tgatggttgg tttggcggtc gtgaaaatga cttcacttca ttaggtgatt gggttgaaac
    17161 agaaggcaaa cttgcttgtg gtttggaaaa tttagccaag caagtgcatg ataacgggat
    17221 gaaatttggg atttggtttg aaccggaaat gatttctgaa gatagtgaac tatttcgagc
    17281 acatccagat tgggcattgg gtattccagg tcgtgaccgc tcaattagtc gaaatcaata
    17341 tgttcttgat ttttcaagac aagatgttcg tgataatatc tatcaacaaa tgacggcgat
    17401 ttttgatcgt gtaccgattg attatgtgaa gtgggatatg aatcgaaata tgacagaagt
    17461 ctattctgtc ttgttggact caacgatgca aggtgaagtg gctcatcgtt atatgttagg
    17521 gttatatgaa tttttagaaa agttaacaac gaattatcca actattttat ttgaaagttg
    17581 ttcgggtgga ggcggtcgtt ttgatgcagg tttcttgtat tacatgccac aaacttggac
    17641 gagcgacaat accgatgccg tggctcgtct gaaaattcaa tatggaacca gcttagtgta
    17701 tccaatttca agtatgggtg cgcatgtttc agcagtccca aatcatcaaa caggaagaga
    17761 aacgagttta actattcgtg gcaatgctgc gatggctggt gtttttggtt atgagctaga
    17821 tctaacgcaa ttaacttctg aagaaaaagc agaaattaaa gaacaagttg ccttttataa
    17881 aaagcatcgc caacttttgc aatatggaac tttttatcgc ttggaaagtc cgtttgaagg
    17941 caatgatact gcatggatgt ttgtctcaaa agaccaaaca gaagccatgg tcttttattt
    18001 ccgagtatta gcagaagctg cgcatccatt agtcacattg aaattagcag gattagcaga
    18061 agaagcaact tatcaaatgg aagatgtaac atttgctggc gatgaattga tgaatctcgg
    18121 tttttatatt gactcagaac tacatggtga ttatgcgaca caacgctttt atttgaaaca
    18181 gatatagtag cttgaattta caatataagt gcaacaccaa aagagactca ttccaaacga
    18241 agaaaatatg ttttatttac acgcatttac taaaaagcag cctgatttga attgggaaaa
    18301 tgaagaagta cgtgaagaaa tctatgcaat gattaactat tggttagata aaggactagg
    18361 cggatttaga atcgatgcga tattaaacat caaaaaaaaa ctagagtatg gcatctttga
    18421 atctgatgga gaagatgggt tagccttcat tgggccctgg attcttaatc agtcgggcat
    18481 tgaagtgtgg ttaaaagaaa tgagagagcg gacatttaaa ccacataata gtatgacggt
    18541 agcagaagcc gatgttccta atgaacgttt agatgaatat attggtgaag atggctatta
    18601 ttcgatggtt tttgatttta gttatacgga tattgatgta cctgaaactg gtgaatggtt
    18661 taaagatagc caatggacat ggacggatat gcgtaccaat atttttacga atcaattagt
    18721 tacgcaagat aaaggttggg gcgccttata tttagaaaac cacgatcaac cacgttcaat
    18781 taataaatat attccagaag aatggatcaa tgattatagt aaaaaaatgt tggcgacgct
    18841 ttttatgtta ctaagaggta ccccttttat ttatcaagga caagaactag gaatgaccaa
    18901 catagaaatg gcatcattag aagattttga tgatgtagct acgcattctc agtataaacg
    18961 ggcattagaa tatggattgg caccagagca agcattgaaa gctgtcaata aacgaagtcg
    19021 ggataattct cgcacaccta tgcaatggaa tacgcaaaaa aatgccagat tctcaacttc
    19081 tgataatgta tggttaaaag taaatcctaa ttatccagaa ctcaatgcag aagctcagtt
    19141 aaccaatcaa cagtcggtat tcaattatta tcatcaatta attaaattaa gaaaaaatag
    19201 tgtatacaaa gacgtgctaa tctacggaca atttctacca gtgaaagata aaaatgaaca
    19261 tattttgctt tatgaacgcc aattagaaga taaaatcgta ttagttatct taaacgttac
    19321 agcaacagaa caagaatatt atgtagatga acagtaccaa caagtattaa tcaataatta
    19381 tgaagatgtt ttattagatc aaagtcgaaa attgcgttta cgaccgtttg aaagtattgt
    19441 attagctaat tatggaggac aattatgaaa attaaaaacg aagcaatgct catcacctat
    19501 gcagatagtt taggaaaaaa catgggcgaa ttaaaacaag tcttagacaa acatttacaa
    19561 ggtgttattg gtggtgtaca tctgttgcct ttttttccat cgacaggtga tcgaggcttt
    19621 gcgccgagtg attatacgac agttgatcca gctcttggaa catgggaaga tgtggaagca
    19681 ttaggtgaag attattattt gatgtttgat tttatgatta atcacatttc tcgtgaatca
    19741 aaatttttcc aagatttcaa aaaaaaccat gagcagtcac catacaaaga aatgtttatc
    19801 cgtattcatg aatttttccc agaaaatcga ccaacacaag aagatattga tttaatctac
    19861 aagcgtaaag acaaagcgcc gtttcaaacg gtagaatttg cggatggtac gacagaagag
    19921 gtttggaata cctttgggga agaacaaatt gatttagatg tgaccaaaga agttgtgaaa
    19981 gaatttattc gagaaaccat caaagatatg gcgaaccatg gctgttcttt aattcgatta
    20041 gatgcgtttg cttatgcgat taaaaaatta gataccaatg atttcttcgt ggaaccagat
    20101 atttgggaac ttttagacga agtgcgtcaa gaagcagcga aatatgacgt cgaattatta
    20161 ccagaaatcc atgagcatta ttccattcaa atgaaaattg ccaatcatga ttattatatc
    20221 tatgacttcg ccttgccaat ggtcactctg tattcacttt atagtggaaa atcagaacgt
    20281 ttagccaatt ggttgaaaat gagtccgatg aagcagttta caacattgga tacgcatgat
    20341 ggaattggtg ttgtggacgc tcgtgattta ttaacagatg aagaattgga ttacacctct
    20401 gaggaattgt ataaagtcgg ggcgaatgtg aagaaggtct attcaagtgc caattacaat
    20461 aatttagata tttatcaaat taacagcacc tattatagtg cattaggcga taatgaccgt
    20521 agctatctgt tagcacgtgc gattcaagta tttgcgccag ggattccaca aatttattac
    20581 gttgggttat tagcaggaaa aaatgatatt gaactgttgg aagcaacgaa agaagggcgt
    20641 aatattaatc gtcattacta tgatttagcc gaaattgaag aagaagtgca acggccagtg
    20701 attcaacaat tatttgcact tttaaaattt agaaatgaat ctgcggcgtt tgatttggat
    20761 ggaacgattg aagtagcaac gccatcagaa tcagaaatag tgattacacg taaaaataaa
    20821 aacggtagtg atagtgcaac attaacggct aacttggata cgaaagaatt tatcattgag
    20881 tctaaagata taaaaatttt cactagtgtt gcattaaaat tttaacctat tccatagaac
    20941 aaaaaatcct ttatactagc acttggatga cttatccaag accaataaaa aggactcata
    21001 catggataag tataaaacaa atacagcatt taataaatgg ttttctgcca taaaattagg
    21061 aaaactttct gtcaactccc aaaaatgtat ttttgattac aattcgtatc gtaaaaaact
    21121 gtcttttgaa gctgtgctca agctctttct ctacgcagtt aatgaagaaa aagaaagttt
    21181 gcgtgatttg agtacagctc ttatcgaccg atcgctccaa ctagaaaccg atgtgtcatc
    21241 gattagtcat acccaattgt ctcgagcatt taatgcactt gaacctaaag tgttagaaga
    21301 aatttttcaa caactgttag aaaaagttca acatcaaatc aaaccaacca agcgaaatca
    21361 tctgtatctg attgattcca gtacgttttc gcttagttta aaacgtcata agtgggcgac
    21421 tttccgtcaa acaaaatcag gtgtcaagtt acacttaaac tattgttata tggacgatac
    21481 tacgatgtat ccaactgatt ttaccttaac aaatgcccat gaacatgatc tcaatcaact
    21541 accagtattg gtgaatcaac cagaggcaac ttacgtgttt gatcgtgggt attaggactt
    21601 tgaaaagatg gatcagatgc attgggatgg ctatttcttc gtcactcgga ttaaaaaaaa
    21661 caccaaagtt cacgtgatag atactctgga aacatcgcca gaaacagaaa ttctacgaga
    21721 cgagctggtt cgtttaggat ctaaaaccta tctaaccgcc aatttccgac tagtcactgt
    21781 tcaagataag aacggacgtg tgtttcaatt tatcaccaat cgaatggacg tctcttcaaa
    21841 agaaatctct gatatgtatc acgctcgttg gcaaatcgaa ttgtttttca agcacatcaa
    21901 acaacacatg accattaaaa ccttcttttc tcaaagtgaa aaaggcgtgc agaatcaatt
    21961 gattttaacg atgatttccg ctctcctcac gtttctcatc aaattggaga cgaaaacgga
    22021 aaaatcagtg ttccaaatca aacgattctt tcgttattta ctgtttcagc cctttgaatg
    22081 ttgtctagaa aaattaattc ccacatgaga aaaaagaaat ttggctcgtt acttttggtt
    22141 ttcagttgaa taacagataa aaaattttct ggaaaaagtc atcctctgcg tcagcacagt
    22201 tttttttgac ttattttcag aggaaatagt tttcagaata ttctaaaatg ttttatgcaa
    22261 cactagtgat attttttaga attagatttc taatgtgcat tttttgagta ttaaggagca
    22321 agtatacaaa gatttataaa gctgattaaa tttgaataaa aatatgcagg aacgctacta
    22381 tttttagtag tgttcttttt tatatttgaa taaaaaatgt ggtggttaaa tggtggttat
    22441 aacaaaaaat gaattaatga aattaggtta tgggaagtat cagtctgaga gaatcatacg
    22501 acaggcaaaa gcaattatgg tttcaaaaag ctatacctat tacgaaaata gaagattagg
    22561 actagtacct gttgaatctg tagaagaagt tttaggtatg aagatagagg tagaggagga
    22621 ttttcagaat catggttaat tttaaaaaag ataaaaatgg gaaatatcat tttactgcta
    22681 gtttgggatt cgacaaacga acagggaaaa gagtacaaaa aaacgtagag gggttaaaac
    22741 agttaaagaa gaaaaaaagc gtataccgaa cttgtttcta attatggaaa agaagcagaa
    22801 acttctcaaa gtactatgtt gtttgaggag tttttttata aattattcct accttattat
    22861 caagggaaag tagaagaaag aacatataaa aatcggttat ctacaatcaa aaaaactttt
    22921 cttatttctt taaaatggag ttaagagaaa tacgtccaat tgacattcaa aagtggcaaa
    22981 ataatttatt gagcaaatat aaaaattctt atgtaagaaa catgtatggg atttttcaga
    23041 tgtcattaga tcgagcagtt gttttgggac tacttgaaaa aaatcctgca aaagttattg
    23101 gaaatgtgaa gaaaaggaaa actacagttg atttttggac aaaagaagaa tttacaaaag
    23161 ttatttcaac tttttatatt gatgatttgt accaacattt tggttttatt tgtatgtggt
    23221 tactttttat gaccgttatg cgtttgggag aagccactgc attaacttgg aaagatattg
    23281 attttgaaaa taaaaacttg cgtgtgaata aaacactcta ttataagaga gccaaaacct
    23341 atgagtttgt agaacccgaa acggcttcta gtattcgtac aatcgaacta gacgacaata
    23401 caattacctt tttaaaagct tggaaggagc gtcaagtttc aataggaggc atgtcgtttg
    23461 tactttctta taatggaaca cctactcaga aatatacaat ccgtcatatt atgagaagac
    23521 atgcaacgat cgttggtgtt catataatcc gcatacacgg attaaggcat agtcatgctt
    23581 ctttgcttat atcacaataa aaagatgcac ttcgaattaa agaaaggtta aaacatgctg
    23641 atgtacaaac gactttagga acttatggtc atttgtatct aaattcattg agagagataa
    23701 caaatgatcc cacagattat atccaaacta atttttctaa aatcaaaccg acacctattt
    23761 acgataataa aaaataaatg ataaacaaaa gtaggatcac accaaaagaa acacactaga
    23821 aaaactataa tacaggcttt tctagcgtgt tgtttcttat ttccgcctat ttatacatta
    23881 tactcataaa gcatttaatg catcgatcgt agccgcattg tctatatggg tatataaagt
    23941 tgttgtattg gtacttgaat gtcccaattg ttgggcagtt aataccaatg aatttgtctg
    24001 ttggtagagt ctagtagcta atgtatgacg cagtttgtga gggctgactt gaattctaaa
    24061 gccttttgaa tattttgcta ccatccgttc gattgcaata ccggatatac gcttggcttc
    24121 tccttggtaa attgctagaa ataaagcttt ttcgttttct gttactttat atcgttcttt
    24181 ccgaatagct agataattag ctaaatattc cattgcgaat gctgctatat tgacagcatc
    24241 tcttttattt ccttttctag ttactaccac attattctta tctaaagata ggtcatctaa
    24301 attaatattt ataacctcgg agagtctcaa tccagatcct aaaatcagtg cattgatcgc
    24361 caggtctctt tctacatctc gttgataata gatcaaagct cgtttactca aagtattttt
    24421 atattcattg gcaatataat ctagataatt ttgtgtatcc ttatctagaa ataatttttt
    24481 ctcaatggca ttggcacgtg cagctaacgt agttttatct gtgatggttg ctacttgatc
    24541 cataggatta ttgtctaagt atggttttcc tagaggatta ttggaacttt tcgaaagata
    24601 tttaaataga acctttaatg ccgtgatatt tctattgata gtagaagtag atagacctaa
    24661 gttattatta tctttgagct tagtttttgt tgtctctttt tttacatttt cttttgtgcg
    24721 acgtttcaaa tgagatttgt acaagtttag gtcataggca gttaactgtc ttatcgaggt
    24781 gatagaagta tcaggaacga tagactcact cagaagccat tcataaaaga gcttataatt
    24841 ttttagatat tctaaagtgg ttcgaggtga ttgatcttta tcctcacgat cttgaacaaa
    24901 atcttttata taatcgggca tatgaagtat gattgtatct attttttgat atatttctgt
    24961 atttttcatg tcattcatcc tttcaataag taggggagaa gagtatctct ataattggac
    25021 tataccaatt atagagtgtt ttgtcaattg gtatgctcta aaatttatta atttgtttca
    25081 aaaaaagcat ataaacaggt atacgtttaa taatttaaaa taaatggtat acataaatag
    25141 ggaaggaaat agaagggagc aatctaaatt ttttgaattt tcttaattaa ttatatagaa
    25201 agaacaatct ttctatagag ttagacatga gagggactat gcttgattta aaatcaacaa
    25261 gcgtatatac tgtatataca aagaaaaagg agggagaaga ctatggcaat taaagaaaga
    25321 aaatttaggg aagtggggaa ctcagtagta ttaactattt caaaggagtt tcttaaagaa
    25381 aatgggttaa atcccggaga tacggttttt ttagatgaag aaaaacttcg agcggcaatt
    25441 acaaaaaaac aagccttatc tgatgaaatt gatttagcaa tatctcaagc attaactgaa
    25501 tatgatacta cttttagaga gcttgtcgat aaatgagtat tcattaccta gaagccaaag
    25561 atattataaa aatgaatgta atccaaataa aaaaatactc tcctaatgaa ccccttggtg
    25621 taaaggatgc gaatgcttta gaaatgtgtg tagggcaact tcgagcctca gcttttggtg
    25681 aagaggttta tccttcgatt tatgaaaaag cagctatcct acttatacaa ttgataaaga
    25741 aacatccttt tcacaatgca aataaacgta ctgctttctt agctactttt gtctttttga
    25801 aaatcaatgg acagctttta gctattgatc aaaaagatgc tgtaaattta gcggtatata
    25861 ttgctacgta tgataaggat ttcgatcaac taaaatatga agtgatcaac actataaaga
    25921 cacatacgca gcccatttaa ggagttactg tatgtgtctt tatagggtta ttagctgcta
    25981 tagcgaaata attgaagtaa attacaaata gctataattc aaatccaact atatagaaaa
    26041 cgtaaatttt ctatatagtt ggattaagat aacgactatt tattttatca tatttttact
    26101 ataccctata cttttacttg gtatatttat gaataatcgc aaatttaccc ctatactact
    26161 agtttgtaag ttagattaat aaaaatacta aagttatttg ttcttttatt aaatacacct
    26221 acaacttata aattgatggt atttagataa cacgaaagaa taaaaataac agctgatagt
    26281 aaagtttgtt gacgattgct actcaatcga aagtgagtta gtgcgtatga acttgcttct
    26341 gaaaacttat gaaatgaaag accttttaca tcttgcagaa atcggtactg ggattaaact
    26401 aagcaataaa aactaatgtt cccctcattc tttgaacttc tactatttga tttatttatt
    26461 ctgataaatg acgatttcac cttcaggatc ttcaaatccc gtatagaatt tatttaagat
    26521 ctcttcagta tcagtaatag gataggcgat aggccacata ccctttgatg gttagaataa
    26581 actgctcaaa atctgtatcg tatgttggct ttagcatatt aacaaaggct atctccaaat
    26641 tataaaccat aagcgttgaa tcgttcttaa caatttcaat tcttcctaac ccaaagtcag
    26701 aagatataat taccggactt gccttaccct tcatgtgggt tgttgagatt ccatatttaa
    26761 agggaattgt cggtactatc ggcggtctga aaaacatccc aaaaataaaa aaatctttcc
    26821 cctgctagtc tcctaagtcc ctttgtagcg gatatggcac cataatctca ttttatcgaa
    26881 gtgagtcatg gtttatctgt tggccaacca aaattgatac aatctaacga tgcaccctct
    26941 acggcattct aggggagtgc acttgcattc acccaataaa aaccggcagt tagcaaagaa
    27001 cttatgtagt cgtatgttct tactgttaac atacaagagg tctcctttcc acaattgctt
    27061 agcagtaaac gggaatttac aaagctaatc tcttccattt tcttatcttt gttctaaaag
    27121 tcccaaatgg agcaactgta tttacatgaa taaatttata tacttcccat acagccgttt
    27181 tggttgcctc gtctgcccat tttcttttgt gtgcagtgaa tagatcttca tcactcattg
    27241 aatcaatcat catgttaata tcatcaatat tacgattgag aatttcctct aattctttca
    27301 atggtagatg tgcataggta tttgtaaacc acttatataa ctctcctaac tgattccatt
    27361 taaattgatc agaaggcgtt ttaacagata atccatttct ttcatcattt tcccatttta
    27421 gaattaaatt cgtccaacca acttgatatg ctaaattttc agcaggtgtt ctatccactt
    27481 cctcaactct tttatccttc aattcttcag gaatagtttc aaattctaaa atatatttag
    27541 tataagtcct atttatttct ttttttaatt cttctttatt tttatatgtt ctcattatat
    27601 tacctccata aattcctaat tgtctccttt aattcatcta taatttcatc cacgatattt
    27661 taatccgttc tacaatgcat atctgatatg cattgactgt ctaactcata tgtgaatgat
    27721 ttataaaata tcccaacgtc tcatctaaag aaa
//
LOCUS       DACBZK010000033        27415 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.033, whole genome shotgun sequence.
ACCESSION   DACBZK010000033 DACBZK010000000
VERSION     DACBZK010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.033"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(106..1293)
                     /locus_tag="IVD66_001497"
     CDS             complement(106..1293)
                     /locus_tag="IVD66_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP6145722.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
     gene            1615..2457
                     /locus_tag="IVD66_001498"
     CDS             1615..2457
                     /locus_tag="IVD66_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAP6145723.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            2454..3404
                     /locus_tag="IVD66_001499"
     CDS             2454..3404
                     /locus_tag="IVD66_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAP6145724.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            3419..3652
                     /locus_tag="IVD66_001500"
     CDS             3419..3652
                     /locus_tag="IVD66_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HAP6145725.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            3983..4567
                     /locus_tag="IVD66_001501"
     CDS             3983..4567
                     /locus_tag="IVD66_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6145726.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            4698..5365
                     /locus_tag="IVD66_001502"
                     /pseudo
     CDS             4698..5365
                     /locus_tag="IVD66_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
     gene            5367..6791
                     /locus_tag="IVD66_001503"
     CDS             5367..6791
                     /locus_tag="IVD66_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP6145727.1"
                     /translation="MKELFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSG
                     KSTLLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQNPRGQFFTTN
                     TTSELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLS
                     LNSKLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVK
                     NRTVKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDIN
                     FDVKVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQF
                     FTESVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSK
                     TNLFLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGG
                     IKKDIKLRVEDSTLIEQIFNDITK"
     gene            6809..7378
                     /locus_tag="IVD66_001504"
     CDS             6809..7378
                     /locus_tag="IVD66_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HAP6145728.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVVSWVLMQLGSAAGQWIPIWFFTDRFRQDWIDRGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            7488..9242
                     /locus_tag="IVD66_001505"
     CDS             7488..9242
                     /locus_tag="IVD66_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6145729.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQYLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHRVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            9196..10968
                     /locus_tag="IVD66_001506"
     CDS             9196..10968
                     /locus_tag="IVD66_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002841847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6145730.1"
                     /translation="MRMQMIGGLTMKNFYKKKFALTDQGAEALTKASISSFFVYCINM
                     VPAFIIMMLIDELVLENAKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLR
                     VQIADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVM
                     LLVGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEI
                     NSFNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLL
                     TGEVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSP
                     LKSFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDY
                     DEGCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAA
                     RLANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLD
                     AENEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSE
                     IYKNLIKKTKLSEKFVYEKEAQSR"
     gene            11491..11760
                     /gene="rpsN"
                     /locus_tag="IVD66_001507"
     CDS             11491..11760
                     /gene="rpsN"
                     /locus_tag="IVD66_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAP6145731.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            11775..11954
                     /gene="rpmF"
                     /locus_tag="IVD66_001508"
     CDS             11775..11954
                     /gene="rpmF"
                     /locus_tag="IVD66_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAP6145732.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            11986..12363
                     /locus_tag="IVD66_001509"
     CDS             11986..12363
                     /locus_tag="IVD66_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145733.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            12384..12533
                     /gene="rpmG"
                     /locus_tag="IVD66_001510"
     CDS             12384..12533
                     /gene="rpmG"
                     /locus_tag="IVD66_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003550836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAP6145734.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            12557..13540
                     /locus_tag="IVD66_001511"
     CDS             12557..13540
                     /locus_tag="IVD66_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAP6145735.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            13570..13692
                     /locus_tag="IVD66_001512"
     CDS             13570..13692
                     /locus_tag="IVD66_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAP6145736.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            13710..15233
                     /locus_tag="IVD66_001513"
     CDS             13710..15233
                     /locus_tag="IVD66_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAP6145737.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFRDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            15257..15496
                     /locus_tag="IVD66_001514"
     CDS             15257..15496
                     /locus_tag="IVD66_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145738.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(15689..16150)
                     /locus_tag="IVD66_001515"
     CDS             complement(15689..16150)
                     /locus_tag="IVD66_001515"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP6145739.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(16345..16563)
                     /locus_tag="IVD66_001516"
     CDS             complement(16345..16563)
                     /locus_tag="IVD66_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6145740.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            16681..18297
                     /locus_tag="IVD66_001517"
     CDS             16681..18297
                     /locus_tag="IVD66_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAP6145741.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            complement(18538..19878)
                     /locus_tag="IVD66_001518"
                     /pseudo
     CDS             complement(18538..19878)
                     /locus_tag="IVD66_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(20154..20309)
                     /locus_tag="IVD66_001519"
     CDS             complement(20154..20309)
                     /locus_tag="IVD66_001519"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAP6145742.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            complement(20605..20937)
                     /locus_tag="IVD66_001520"
     CDS             complement(20605..20937)
                     /locus_tag="IVD66_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP6145743.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            complement(21451..21642)
                     /locus_tag="IVD66_001521"
     CDS             complement(21451..21642)
                     /locus_tag="IVD66_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6145744.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            complement(21736..22122)
                     /locus_tag="IVD66_001522"
     CDS             complement(21736..22122)
                     /locus_tag="IVD66_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP6145745.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            22816..24021
                     /locus_tag="IVD66_001523"
     CDS             22816..24021
                     /locus_tag="IVD66_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HAP6145746.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            24038..24472
                     /locus_tag="IVD66_001524"
     CDS             24038..24472
                     /locus_tag="IVD66_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145747.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            25089..>27415
                     /gene="esp"
                     /locus_tag="IVD66_001525"
     CDS             25089..>27415
                     /gene="esp"
                     /locus_tag="IVD66_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HAP6145748.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
BASE COUNT         9407 a         4020 c         5132 g         8856 t
ORIGIN      
        1 caagtaaaaa ttagccaaat caaaaaatat tttataacag ataattccga aaaaagggta
       61 caacaaataa gcttcttacc attagttttt ttgaatgttc aatagctaat cagaaacaat
      121 tatataaggc tcgtttttag tcaaaatagc atgaatcacg taacaaagct tacgagaaac
      181 cgcacctaag gcagttagat gatgttttcc ttcggaaact tttttctggt aaaacgcact
      241 aaaaacagga tcacattgag aagctactaa agccgccgaa aacaaggctt ttcgcaaata
      301 tggagaccct cgtttactca taacattatg cgttgcctca tattgccctg attgtgtcac
      361 ggaagcgtct atcccagcgt aagcaacgag ttttttcggg ttagaaaatt tttgaatatc
      421 tccgatctca ccaagaatag tcgcaccgtt tataggacca attccaggaa ttgtgagaat
      481 aacagaattt aaagtgtcca ttatgtgctt gatttctctt tccgtttcct ttatttggct
      541 ttcaatgaat tttaattgtt caatcattga acgtagttgg aaggtgaacg cttcttgagc
      601 aaattttact ccaaaggagt tagaagctgc ttgcttcaat tggtccgctt tttctgcctt
      661 gattcggttc ctgcttaact cagctaagta ttgggccaaa gtttctgagg aaatgttttc
      721 taagtcgatc ggggcactaa acgccagcaa taactcttta gaagcttttc cgaaaacgcc
      781 ctgcttggta aaaatcgtcg cgtattctgg aaagacttga tccaatacgg ctataatttt
      841 tcttttgaag tcgctcgctg tacctactaa ataagttcgg taacgagaaa gttgtttcaa
      901 agaaaaaaca ttttcatcgg ataagaccgt ttcgacaaat gagccatagc gcattaagtc
      961 agcaatcaaa acagaatcaa taatatcgtt ttttcgtttc cgtatttctg tacctttacg
     1021 ccatccgtct gtttgaaggg gattcacaac gtgaatcaaa taatctgatt cgtgaaggta
     1081 tgaaaagatg gacagccaat agtgccccgt ggcttccatc cctataacaa agtcactggg
     1141 tgctccggaa tagtcgacca ttcgctcaat taatgactct gctccttcag tggtgttagg
     1201 aaatgaaaaa ccttttagta atacctttcc ttcctcgttc atgatagaag caacgtgagt
     1261 gcgtttaccg atatcaatgc ctaaaaagta catgtatatc tgacctttca aaaaaagaat
     1321 tttggattga aatccactca actgaaaagc gtcactacct tgtacgagat acggagtaaa
     1381 gtaaggactt tcaacatcta actcatacgc aatccactta tcagagagag gagccagtct
     1441 ctcgagtgcg ggttcaatgg cccaaggggg gaacggctta gcctctcaat ccaataaata
     1501 tattatctca aaagaaatga gttaatacca aattaaaata acgatggttc atagggttat
     1561 ccaatcaaaa ccggaaggtt aaaaccctaa ctctaatata caagggggaa taatatgctt
     1621 caaaatttta ttaatggtct gtatgacttt cactttttac agaatgctct aattacatct
     1681 gtagttatag ggattgtttc tggaacagta ggttgtttta ttattttaag aggaatgtct
     1741 cttatgggtg atgctatttc tcatgctgtt ttgccaggag tagcaatttc ttatatttta
     1801 ggtattaatt tttttattgg tgcgattgta tttggtctat tagcttctat cattattact
     1861 tttataaaaa gcaatagtgt aataaaagga gatacagcaa ttggtattac tttcagttct
     1921 tttttagcat taggagttat ccttatagga gttgcaaata gctcaacgga tttatttcat
     1981 atcttatttg gaaatatttt agctgtacaa gatattgata agtggattac aattggcgtt
     2041 tctgttttag tgttggttac agttgttcta ttttttaaag aattattaat cacttctttt
     2101 gatccattaa tggcaaaagc aatggggatg aatgtcagtt tttatcatta tctattaatg
     2161 attctattaa ctttagtagc agtaacagct atgcaaagtg tgggaactat attaattgtt
     2221 gcaatgttaa ttacaccagc tgctacagca tatttatatg caaacagctt aaaaactatg
     2281 atatttattt cggcgacagt cggagcgtgc tcatcattgc taggtttgtt cattggttat
     2341 agttttaaca tagcagcagg atcaagtatt gttttaacag cggcattctt atttgtaatt
     2401 agttttctaa tctcaccaaa acaaaaattt ttaagaaaga aggagagaaa gttatgatga
     2461 gaaaatggaa agcagtactg ggaagtctgg ggattttgat tgctcttttt atattcgggg
     2521 catgttcaac aaatagtaaa gacaaagata cagtggcttc gaacgaaaaa ttaaaggtag
     2581 tagttactaa ttcgatttta gcagatatta ctgaaaatat agcaaaagat aaaattgatt
     2641 tacacagtat cgtacctatt gggaaagatc cccacgaata tgaacctttg cctgaagatg
     2701 ttcaaaaaac ttcaaaagca gatttgattt tttataacgg tgttaacttg gaaactggag
     2761 gaaatgcttg gtttacaaaa ttagtaaaaa atgcgaacaa agaggaaaac aaagactatt
     2821 ttgcagcaag tgatggcata gatgttattt acttagaggg tcagagtgag aaagggaagg
     2881 aagatcccca tgcttggtta aatttagaaa acggtattat ttacgctaaa aatattgaaa
     2941 aacagttagc ggaaaaagat cctgataata aaaaattcta taaagaaaat ctagataagt
     3001 atattgaaaa attggattct ctagacaaag aagctaaatc taaatttgct tcaattccga
     3061 atgataaaaa aatgattgtt acaagtgaag gatgctttaa atatttctcg aaagcgtata
     3121 atgtgccttc tgcttacatt tgggaaatca acactgaaga agaaggaaca ccagatcaaa
     3181 taaaacactt agttgaaaaa ttacgcacaa caaaagttcc ctccttattc gtagaaagca
     3241 gtgtggacga tagaccaatg aaaacagtat caaaagatac caatattcct atctattcaa
     3301 cgatttttac tgattcaatt gcagaaaaag gacaagatgg tgatagttac tatgcgatga
     3361 tgaaatggaa cctggataaa attgctgaag gcctttcgaa ataatttgga gggtaggtat
     3421 ggtacaaatt aaaacgacta ctatactaat ttatttacta gcaattcagg aattatcaaa
     3481 aagaaaaaag aaattaaaaa ataatgattt agcaaaagtt ctaagtgtta gtccagcatc
     3541 tgtaagtgag atgctggcta aacttagata tgaggactat ttagatatag gatttcaatt
     3601 aactgataaa gggaaaaaat ttattgacga ttacaaaaaa ggttttaagt aaaagacttt
     3661 atttttaggg aggataagaa aatggctatt ggagtgatta tgataggact taccctaata
     3721 gctggatata atttttttaa atctttctcg gattatttta gaaaaggtga atgatttaga
     3781 tgagtctatt aattcttgta ggattgcttt ttgtatcagt tattttgctc tttctcatta
     3841 gtttagctct aaggaatgag ttcagtaata gacgttaacg attgaaactt caagtcctgt
     3901 gtaagataat atagttaatt catcttatta ggaggaagta cccatagaaa ccagagatta
     3961 tattacaact caccaaaaat taatagaaag tggactaagc cattttgaaa aagaaggatt
     4021 tcagcaaact aagataaggc aactgtgctt gaccgcaggc gtaactacgg gtgcttttta
     4081 taaacatttt acttctaagg aagcgttatt tgaagaaatt attcagccgc atattaatgc
     4141 gcttattaat atgtataatg aagagtttac caaatacctc ttaaacttag aaaatataga
     4201 tatagagaaa agttggagag agaacttcaa tgaattagat ccatttatta attatatttt
     4261 tgagaataaa cgtatattcg atttggtttt attccaatca gctggaacca aatatcaaga
     4321 tattgttgaa aaaattacat catttgtgac aaaaaagaca gtctgttgtc tagataagtt
     4381 aaagactatc ggaatgatca atcaaaattt agtctttaat gaagaagaaa tccacttcta
     4441 catttactca ttctacgcta cattctatga tatattgaag catagctatt caaaagaaaa
     4501 gactatgcta ttaaccagaa gattgtatca attttctgtt cctgggtgga ttgaattact
     4561 gagttaatta aaaaaaagct tgcattgaga attgttctca gttatgcttt ttgataagat
     4621 cgcactgtta tctgaataac ggtgcatttt tgtcagctta agataacagt gcgatcttat
     4681 tttttggagg tgaaagagtg tcaaaaatca atccgttaac cttgattact ttaaatattt
     4741 ttttccggtc attatttttt taggaaaggg aaatatattt caagtggggt gtttcattat
     4801 tgctacagtt ttagtattga tgtttcgtaa aataaagaca tgtatttatt tcatcttgat
     4861 ttattcagtt ctgtttttag taatgaaaat tattgatgct atcaagatag agttttttac
     4921 tatatttttt gggacatcct tatatattgt atttcgaatg ttgccggtcg taatgatctc
     4981 atggttgttg gttagtgtct atactagcaa tgaattatta tcctctttag aaaaaataca
     5041 tttaccgaaa aaaataatgt taagtattac agtagtgatc agattctttc cgacttatcg
     5101 ttctgaaata agaatgatta aagaatcttt aaaaatgaga aacattcgct tgtctttttt
     5161 tcagcctctg caatatttgg aatttctgtt agttcccgtt cttatacgtg caactatgat
     5221 tgctgaagaa atgaccgcta atgcaataac aaaggggata gaatctcctg tgaaaagaag
     5281 ttcttactat aaaacaaaca tgagcttatt agactatatc atcctgtttt ccgttactat
     5341 ttttttctta agtattttga tttgaggtga aagaattgtt tgaatttaac aatgtttctt
     5401 tttcatataa ggatgttaag gaacaagcgc ttgttgacct taatttttca ataaaaaaag
     5461 gcagtcttac attgattact ggttcttctg ggagtgggaa atccacacta ttaaagttaa
     5521 tgaatggact tattccaaga ctttatgacg gaaaattggt tggggaaatt ttatttgaaa
     5581 ataactcgct acaatcctta acacaagaaa gtatatcaaa aaatattggc tacgtaagtc
     5641 aaaatcctag aggacaattc tttacaacaa atacaacgag tgagttagta ttttcgatgg
     5701 aaaactttgg atttacaaaa gagcatatgg ataaaagaat caatgaatta gctgaattat
     5761 tagatctttc aaatatatta gataaaaaca ttttttcgct atcaagtggt gaacggcaga
     5821 aaatttctat tggatgtagt ttatcgctaa actctaaatt aattatattg gatgaaccgt
     5881 cttcaaattt ggacttcaaa gcgactaaga aacttgctga cttactttgt gatttaaaaa
     5941 ataaaggatt tactattgtt atagctgaac atcgttttta ctatttgaaa gaattaattg
     6001 atcaagttct atttgttaaa aatagaactg taaaaactac aactattcag ttgttaaaaa
     6061 ctgaaaacaa taacgcatta aggaaatttg acatttttaa tagttcgatt gaagttccct
     6121 atatcgaaaa ggtaagtgca gatgtattaa aagttgaaga aattacttat gaaaatattc
     6181 taaaagacat aaattttgat gtcaaagttg gagatgttat tggtttggta gggaaaaacg
     6241 gtgtggggaa aacaacctta ctaagaatac tcatgaagat tattcgccct accaaaggaa
     6301 agataatcga aaataaaaaa aatttgtcat cgccgttttt agtaatgcaa gaaatggatt
     6361 accaattttt cacagaatca gtgaggagcg agttagccct ggggaatgaa atagttagta
     6421 aagatcagca agaaaaaatt ttaaaaaaaa tggaacttta taaaatgaaa gatcaattac
     6481 cgtttgattt atccggtgga gaaaaacaaa gattattggt ttctatagct tcattgtcaa
     6541 aaactaattt atttctattt gatgaaccta caagtgggtt ggattatatc aatatggaaa
     6601 ggattgctga ccttattaaa gacttaaaag aaaagggtgc agtagttata gccactcatg
     6661 atccggaatt tctttataaa acatgcaata gaattattta tttaaaaaat ggtggaataa
     6721 aaaaagatat aaaacttaga gtagaagatt caactttgat agaacagatt tttaatgaca
     6781 taacgaaata gaattgagga gaatatatat gaaaacaaaa gattatattt ttattggttt
     6841 agctacagtt atttccctag taatttactt tttttcaata atggttagta gtattggtgg
     6901 ggcgtttggt cacagcatat ccccagggat ttttggatta ttatctggaa tcatatttgt
     6961 ttatattagc tataactacc ctagaaaagg aatttttact atttacacaa ttgttttatt
     7021 gttatttttt acgttaatgg gcggggcgta cttaccttgg tttatcagtt cgattagtat
     7081 ggcgatctta gctgatatta ttctatctgt atttggatat gatcgagcaa ttcctcaagt
     7141 tgtgtcttgg gttctaatgc aactaggcag tgctgccgga cagtggattc ccatatggtt
     7201 ctttacagat cgttttcgtc aagactggat agatagagga caatctgctg caacaatgga
     7261 tgcaatgatc cactacgcgg tgggtatatg gggaattatt tcagtgttag ttgtagcaag
     7321 tttatctatg attggtgtat tgattggaag aaaagtctta aaaaaataca aaaaatagaa
     7381 cgtagtttac cttctatctg tttgtacatc tctaatttac gctattacgg aaagcattaa
     7441 cagttgtaaa cgaataagag aagaaattga atgcggggga ggaaaaaatg aaagtataca
     7501 aaaaattatt tagttatgtc cctaaaatga aatactacgg atggttagcc actttatttt
     7561 ctgatttttc tgtcgtatta acagtctatg gatattacag tatttacaaa tttcttcagt
     7621 ctctaattat tgtaggagat gaatatttag ctaagagtta tgcggttcaa actgttgctt
     7681 ggttaacttt aggagcttta ttttatattt tttctggctt attttctcat atccttgggt
     7741 ttcgcttaga gactaatttg agaaaaaagg gaattagcgg tttaacagaa gcaagttttc
     7801 gtttttttga tttaaattct tcgggatata ttcgaaagac aattgatgac aacgcggcta
     7861 aaacacatat ggcaattgct cacttgattc cagatagtgc tcaagccata gtaacacctg
     7921 ttttatcagt tgccttaggc tttttcatta actttaaaat tggattggtt ctaatcgcca
     7981 tgttagtaat tggtgtattc ttgttaaaga aaatgacaga gaatacaaat tttattcaaa
     8041 aatatcaaga atcgttagat gtgttaagct ctgaaacggt agaatatatc cgcggaattc
     8101 aagttataaa gatatttggt gctaaagtaa catcatttaa agccttgaat aaagcaatta
     8161 acgattatgc taagtttgca tataagtatt ctttgagtgg gaaaacacct tttgttcttt
     8221 ttcaatggct attttttggc atagtttgca ttttgatagt tcctataacc ttttttataa
     8281 cttctcttac cactcccaag atcttagctg ttgacttgtt gatgttgttt tttttaagtg
     8341 gaattatttt tgtttctttc atgagaataa tgtatgtaag tatgcacttg tttgaagcaa
     8401 gatatgcagt cgaaacacta gactcccttt atttagaaat gaagcaagac caactaaaat
     8461 atgggaacga gacacagatt aaaaattgtg acattgcatt tgaaaatgtc agcttttcat
     8521 acaaagaaga gtgtgtttta gaaaatttca acttagtttt agaacaaaaa agaatttatg
     8581 cattagtagg aaaatcagga agcggaaaga gtacgatagc taaactaatt tcaggtttct
     8641 acaatgtgga taagggacag attaaaattg gtggtaagcc tttaaatcac tattcaaaag
     8701 acacaattat taacacaatt gcttttgtct ttcaagatac gaaactattc aatcagagta
     8761 tttacgataa cgtttctata gcaaatcctc aagcgccagc aagtaaagta tttgacgcgc
     8821 taagattagc cggttgcgaa tcgattttag aaaaatttcc cgaaagagag cataccttaa
     8881 ttggtagtaa aggagtttat ctgtcaggag gagaaaaaca acgtatagct attgccagag
     8941 caattttaaa agatgcaaag attgttatta tggatgaagc cagtgcatct attgatccag
     9001 ataatgagta tgaactacaa aaggcttttc aatatttgat gaaagaaaaa acagttatta
     9061 tgatagctca tcgattatcc agcattaaat ctgtagatga aattcttgtc ttgtcagaag
     9121 gaaaaatagt agaacgtgga aatcataatg aattaatggc taaacatcga gtgtataaac
     9181 aattggtcac taattatgag aatgcaaatg attggaggct tgacaatgaa aaatttttat
     9241 aaaaaaaaat ttgctttaac tgatcagggc gcagaagctt taactaaagc ttctatttct
     9301 agtttttttg tatactgcat taatatggta ccagcattca ttataatgat gctgatagac
     9361 gaattagttt tagaaaatgc aaagccccgt tggctttatt ttgcagtatc gtttgttact
     9421 ttgcttttca tgtattggtt gttagatagg gagtatgaaa acttatataa tagtacttat
     9481 aaagaaagtg cgcatttaag agtgcaaatt gcagacgatt tgtcaaattt accattatcc
     9541 tatttttcaa aacataattt atcagattta tctcaaacta tcatgtctga cgttgaaggt
     9601 attgagcatg cgatgagtca tgcaatacct aaagccggcg gtatggctct gtttttccct
     9661 tttatttcag tgatgctttt ggttggtaat gtcaaaatgg gattagctgt tattttgcca
     9721 acgttattta gttttgtctt aatcttgtta tcaaagaaat cccaaacgaa agccaatact
     9781 aaatattacg atactttgag agaaaactcg gaagaatttc aagaaactat tgaattgcag
     9841 caagagatta atagctttaa tctatctaaa aaagttcaag acagactttt caaaaaaatg
     9901 gaagagagtg aaaggattca tttaaaggta gaattaagta ctttttcagt catggcctta
     9961 tcctctattt tctcatatgt tagtttagca gtagtcattc tagtaggtgt tcacttactg
    10021 ttaacgggtg aagtgactat actctacgtc gttggttact tactagccgc aataaaaata
    10081 aaggattcct tcgattctat gaaagaagca gtgcttgaaa tattttattt agctcctaaa
    10141 atacagcgaa ttagagctat gaaggaaacc agtatccaag agggatcaga tagtcctctg
    10201 aaatcttttg acattgagtt gcgagatgtc tctttctcat atgataacaa taccccaatt
    10261 ttagatcata tctcttttac ggctaaacaa ggagaagtga ctgcgttagt aggtgctagt
    10321 ggttccggga aaactagtat cttgaaatta gtgtctagac tgtatgatta tgatgaaggc
    10381 tgtattttaa ttgatgggta tgatattaaa cgtgtatctc cagcttcttt gtttagcaaa
    10441 atcgctattg tttttcaaga ggtaactttg tttaatacaa gtattttgga aaatatacgt
    10501 attggaaata gtcaagcgtc agatgaggaa gtgaaaaaag cagctcgttt agctaactgc
    10561 gaagacttta ttgaaaaact acctgacggt tatcatacat tggtcggaga aaacggaagt
    10621 tcactttctg gaggagagcg acaacgccta tccatagcac gggctttttt gaaaaatgcg
    10681 ccaattttaa ttttagatga aattactgcc agtttagatg cggaaaatga aaaacgtatt
    10741 caggaaagtt taaatcgttt aatacaagat aagacagtac taattatatc gcatcgcttg
    10801 aagtctattg aaaaggtaaa taaaattgta gtgatggatc aaggaaaact agttgatcaa
    10861 ggtactcata atgagttgta tcgaaggtca gaaatataca aaaatctcat aaagaaaact
    10921 aaactatctg agaaattcgt ctatgaaaaa gaagctcaat cacgatgatg aaataggctt
    10981 taaattaacc tacaattttt gggatatagt tataattctt tttcaaaaag aataatttta
    11041 ttaaacagca tctaattttg aatacacgaa agaatcagta tgattgaatt agttcactta
    11101 atgtctattc ttataatata aggaataatc aaagttttaa aaaattggcg ataaaccagt
    11161 taaacataaa agattgaata aaaagttata gtttctttca tattgccgtt ttaagtagag
    11221 gaaaagctac ttaaaacggt atttgtgttt gattggacta ataaaagtga attcttattt
    11281 ttcagagcct aaactgcata ttcttttaaa tgatttgatt atctctatgt accgataaat
    11341 tcgttttcaa atagttatct attcatatga gttttatttc atgttattta ttgttgacaa
    11401 gagcaactct tgttggtaaa gtatcagtgt caaaacgtaa cgattacgat ttgaggtgtc
    11461 taaatcaaaa taaaaggagt ataaaggtat atggcaaaaa agtcgaaaat tgctaaagca
    11521 aagaaacaaa tggcgatgat tgaaaagtat gcagataaac gtcaggaatt aaaagccgca
    11581 ggagatcgca ccgctctcgc taaattgcca agagattcaa atccgaatcg tctgaggctt
    11641 cgtgatcaga cggatggtcg tccaagaggg tatatgcgaa agttcggtat gtcccgtatt
    11701 aagtttagag aacttgccca tcaagggttg attcctggag taaaaaaagc aagttggtaa
    11761 aaggaggaaa tatcatggca gtaccagcaa gaaaaacatc taaggcgaag aaacggttaa
    11821 gaagaactca tcaaactgta gtaaaaccag aaatttcatt tgacgaagcg aatggtgatt
    11881 atagacgtag ccatcatgta tctttaaaag ggtactataa tggaaagaaa gtaattaaag
    11941 gagcttcaaa atagtttaat atataacttt taggagggaa tcaaaatgga aattatttac
    12001 ccacctttag ttgaagaagg attaaagtat tatcttgaaa cgacccagca atcgctagat
    12061 aaatgcactt tttatcgttc gatggtagag agaggaatta ttactgaaac gggtttaccg
    12121 acccaacagg caattgaaaa tggattagtc aaagattact atgaggacca aggcttatca
    12181 tttgatgatt ttttaagaat ctatccaatt tttgaagagt atgacgagga gttatttcaa
    12241 tgtatcgatg gttattggga gatacctgtt gatatgaaag aaaatttagt ttcacaattg
    12301 gaatctggcg agttaacttt tgaagatgca caacaaattc aagcatatct tgaagatcga
    12361 taagtattga aggaggaaga tttatgcgtc aaaatattat tttggaatgt gtcgaaactg
    12421 gagaacgtct gtatctcacc agcaaaaata aacggaataa ccctgaacgg ttagaattaa
    12481 aaaagtattc gccaaaattg cgcagacggg caatttttaa agaagtgaaa tagctaagtg
    12541 gtaaaaaggt gacaaaatgg gcataccagt tacaatcgtt tctgggtttt taggggctgg
    12601 aaaaacaacg ctaatcaatc aagccttgca agtctcaccc taccccaggg aagaaattat
    12661 tataattgaa aatgagtttg gtgaagttgg gattgatcac aaattattag ttcatagcga
    12721 ggaacgggtg ttacaactaa ataatggatg tatgtgttgc agtcttcgca gtgatttatt
    12781 agcaatattg atttctttac tggaaacaat agaagaacat caacaaccaa tttcacaaat
    12841 catcattgaa actacaggta tagcagatcc ccaaccaatc attcaaacac ttttaacagc
    12901 gcctcaacta agaggaagag tatatatcga tagtttattg actgttattg atagtgacag
    12961 ttttgaactt attgaaagag aaccacaagc ccttaagcaa cttgtcatgg cagatcgcat
    13021 ttttgtgtct agaaaacaaa acttgaattt atctgcacta aaaaaattac agagagaaat
    13081 caaaagtatt aaccctttat ccgatattcg aatgttcaca catagtgaaa cgattcaaaa
    13141 aaaggatttt tataatttga aaaaatttaa tcatccctta gtttttgaaa gtgattcatc
    13201 agaaaatcac tataatggca aatactatca tcaacaccat caagtacatg agtttaaatc
    13261 aattctctta acttcagatc aagacataaa aaaagatttt ttactccaat ggattgactg
    13321 gctgatttta accaaccaag ggagcctgta tcgttttaaa ggattgattg ctttacaaga
    13381 gcaggatttt atagttgcca tgcaagaggt aaacgaacag gttaattttc aatacaccac
    13441 tcgacaaaaa gaccaaacca ctattattct aatcggaaaa atgttggatg aagaaaggat
    13501 caaacagagt tttgataaat tactggcgga aagcaaataa tgataagtag tgattggggg
    13561 taatttctaa tggagaaaac ggatatatct agtgcatatc gacgacttaa aagcccgaat
    13621 attaaaacta gaaaaagggc attaaaaatt atcaaagaac ataaacgaaa taaaatgaag
    13681 aaattagcat aattaaggaa ggaaaaagaa tgaagaaaat cagtgtagga cttattggga
    13741 tagcagctct aggattattg ggagcttgct ccagcactaa tgatgcaaaa gtatcgaatg
    13801 ataaagatgg aaaattagaa attgtaacaa cattctatcc aatgtatgat ttcaccaaaa
    13861 acatcgtcgg cgatgaagcg aacgtggatt taatggttcc agcgggatca gaacctcatg
    13921 actatgagcc ctcagctaag gatatggcaa aagctcatga tgctgatgtt tttgtatatc
    13981 ataacgaaaa catggaatca tgggtaccaa aagctaaaga aagttggaag aaagctgggc
    14041 ctaatgtagt agaaggaaca aaagacatga ttttattgcc aggtagtgaa gaagaagatc
    14101 atgatcacgg agaagaagat caccatcatg aactagatcc tcatacgtgg gtttcaccca
    14161 aaatggcaat taaggaagtt tcaaatatca aggatcagtt agttaaattg tatccgaaaa
    14221 aagcaaaagt atttgagaca aatgctgaaa agtatttgac taaactgaaa cggttggatg
    14281 ctgactatac cactagtctt aaagaagcga aacaaaaaag ttttgtgacg caacacgcag
    14341 cctttggata tttagctttg gattatggat tgaaacaagt tcctattgct ggactaagtc
    14401 ctgaagaaga gccatcttct ggtcgattag ctgaattaaa agagtatgtt aaaaaaaata
    14461 agatcaatta tatttacttt gaaaagaatg ctaatgataa aattgcaaaa actttggcca
    14521 acgaagctgg gataaaattg gaagtactga atcctcttga aagtcttaca aaagaacaaa
    14581 tggataatgg tgaagattat gtttcagtaa tggaagacaa tctaaaagcg ttagaaaaaa
    14641 caactatggt tgctggtgaa gaggtagttc cagaaaaaga agcgaaggat gaaaagacag
    14701 ttgctaatgg gtactttaga gatgccgatg tgaaggatcg cgaattgagt gattatacag
    14761 gcgaatggca atctgtttat ccgttgttaa aagatggaat tttggatgaa gttttcgatt
    14821 acaaagcaaa aatcaataaa gacatgacag ctgccgagta caaagattat tatactactg
    14881 gctataagac agatattgat actatcaaca ttaaagacaa caccattgat tttgtagtca
    14941 acggtgaaca tcatcaatac acatacaaat atgttggata caaaattttg aattatgaaa
    15001 aaggaaaccg tggtgttcgt tttaattttg aaactgatga tgcaggtgct ggtcgtttta
    15061 aatatattca atttagtgat catggaattg caccaagtaa ggcagagcat ttccatattt
    15121 tctttggtgg agaaagtcaa gaaaaactct ataatgaatt gcataattgg cctactttct
    15181 atccagcttc attgtctaaa catgaaattg ctcaagaaat gatggctcat taaaattcaa
    15241 tttttggagg aaatacatgg taagaaaagt attattgtct atggattcca agaatattga
    15301 tgcttatcgg cgttatcgat ttgcaaagca aatgagatta aatgggagta cattagctga
    15361 tattgctgca actttacatg ttagtattga cacagttcat agagtattaa aacgggatcc
    15421 tgattgttgt tttatcaagg tcaatactgg aagaagtaga cgtttagcaa aacggcataa
    15481 tagcttggcc aattaattga taataccaga gtagatcatt tttcccttat ttggatttga
    15541 tctgcttttt attatgtctt gaattgtcaa atcaagcgca acactttatc aaagaagact
    15601 tcataaggtg ttctccaatc taaacacttt ctaggtctgt tattcagttt ttcaatcatc
    15661 tgatttatcg ttgagttatc taccgtagct atctctttcg attttggcaa gtattctcga
    15721 atgagtctat tcgtatttta atttgttcat tgttgccaag ggcatgagga tctggaaaat
    15781 aaaagggcat attattcaat gcttctgtaa ctgcgaaatg attggagaat tcttttcctc
    15841 tatctggagt gatcgttttg accgcctcat ttggaatact gcttaaaagt tcaatcattt
    15901 tctcgctcac ataagcggct ttctttctgg ggaccttctt tcctgctaaa aggaagcatg
    15961 attttctgtc tgtcaaagtc actaaacaag taccaccagt tttgccagct acaatatcgg
    16021 ctttccaatg accaaaatca cttctatcat ctgcggattt tggacggcca tggatcgaat
    16081 gagtaaggca aatctttcca cgagactcga catgattttt tgtatgtctt gtttttcctc
    16141 gatggtgcaa tgaacggatc aggcctttat tgccgtgtga gaggggttct gtatcgaaaa
    16201 gatcattgca aattgcacgt tagatcgtga taaaactaat tgaaaagtcc atatgttcat
    16261 gcttcaaacg attcgagatt tcctctggcg accactgaaa atcgacaaat aaatgacgaa
    16321 caattgacca aactcacgga tcatttagaa tgtgataacg tccgcatttt tttcttcgat
    16381 aagcataatt tttttccgct ttggaaggtg aatagttttt ttcttgtttc ttctcagttc
    16441 atgtaaaata gtaaacgggc tatgctgaat gtcgttgcca attatactaa tagaaaatcc
    16501 ttcttcgtga agcagaaaga ttctttctcg ttcgagtata gtaagatgac gatactggct
    16561 cataattatt ttccttctag gagtgttctc gacaaactta tactagttgg atatcgatta
    16621 tgactcattt ttatgtgttg cacttaaagt gtaaattcaa ggtatagaaa gaggttccct
    16681 atgaaaaaaa tacctattac aatcttaact ggctatcttg gttcaggaaa aacgatactt
    16741 ctaaatcata ttctgtacgg tgatcacgga aaggaaattg ctgtcattgt aaatgacata
    16801 ggggaagtaa atgttgatgg ggtattagtc gacaagaaag gttttaaaag aactggagaa
    16861 aaacttgttt cgatgccgaa tggatgcatt tgttgtacat tacgcgaaga tttgattgtt
    16921 gaactagatc aattagtgca attttctgac ttgaatcaaa ttgttattga agcttcagga
    16981 atcagcaaac caattccaat tattcaagca attatattag ctaaaaaccc tttagacatt
    17041 gatttgaccc aacgattaga gattggtgcc attattatag tagtggatgt aaaacgtttt
    17101 tgggataatt tcgaaacggg tgaaaagatt caggaaagaa aagctgaagg taatgtagtt
    17161 gaagaagaac aggatattcg tggcttgtta attgatcaat tcgagtgttg taacatatta
    17221 cttttaaata atagtgactt agtgtcaacc aagacgattt acaaaattaa cggtctaatt
    17281 gctaagttac agtccaatgc caaaataatt aggacaatta aaggtgaagt agacttatcg
    17341 aaaattctaa atacaaatct ttttaatata gatgagactt cctattcagt gggctggttc
    17401 aaagagttag agcttggcta tcaaaatcat attcctgaaa cagaagaata tggtatctca
    17461 agttttatct atcgaaatcg gttactcctt gacgcacaaa aatttgccca tcttacggat
    17521 aaaaattttc ctggcaatat tacaagagca aaagggtttc tttggtttgc ccaacatagt
    17581 gatttttcga cgatctttga aacatcgggt agctataaaa gtattgaatc attaaattat
    17641 tgggtagcta gtttacctaa aattgagtgt caaatgatta tacaaaaaaa tcccgaattg
    17701 aaggaagcct ggcatccgtt gtttggtgaa cgcattaata aactagtttt tattggtatg
    17761 aagatggatc aacaatgtat taaggaacaa cttgagggtt gtttaactga ttctcttaat
    17821 gcagataatt tccgaaaaat ttcaccattt ccatggaaaa agtctaatat gtttagccag
    17881 atatcgttaa tgaaattttt aagaaaagct ggtgtcaaga taggcgatgt cataattatt
    17941 ggcattttga ttattacctc ttttattccc ttatttgtat tctctataga aaaggagaat
    18001 gaaacaactg aagatgctat caaatatgcc atcgttcgaa ttgatggcaa ggaaatggat
    18061 cgcttcgatt tggataagat caatcataaa ctcgtgaatt atcatcctgc gaagggacaa
    18121 tataatattg ttgagattaa agatggaaga attcgagtta aagaagataa tagtcctgat
    18181 caaatcgcgg ttagaactgg atggatctca aaacccggtc aaacgagtat ttgtttaccc
    18241 cataagttag ttattagtat tgagaaaaaa gaaagcacag attactacat ttactaatct
    18301 ggaaatagat gaggaggttt ttaataagaa aaagatatta ttattaataa tagcaggggc
    18361 tttattaagt gtgttaagcg cttgtggaca agaaaaagaa gcggtgacaa caggcacaag
    18421 tatctttaac gggacctgca atggtttagt taacagtcgg ttagattact tattttggct
    18481 cttcgtcaat gagtgttggt gaagaaattc aatagaataa tcgagatact cacacggcta
    18541 gacagctatc ttgtctagcc gtgttgttgt tctggcttta gtcagttggg tagtattctt
    18601 agttttctta aaatattttc ctcgatataa aaagattcgt tctcggtagt tttgaaagtt
    18661 tctatagcca taggcaattc gttttagtac tttgatatgg ttattcaaac attctatagg
    18721 gccgttggaa tagggaacgc gcaacgctcg tttgatttct gtttggtatt tcttgaaggt
    18781 cgtgaacact ggttggtagt gctctggcaa ctccttgtag tcttctttta ggagcgcgac
    18841 gaattcagga acatcttgtc ttctgataac ggaaagaaaa tcctggtaga cttcgtagcc
    18901 tcgctttaag gaatcatcat aagataatag ccgatcgact atctctgctt ctgtcagatg
    18961 atctcgaaat gacggacgcc agtagcgatg ctgacctttc aattcccacg cattcttttg
    19021 aagtagtttc cagtatttct ttaagtgctt cgaccgacga tccccttttt taaaggtctt
    19081 cattacttga attcggtggt tggtaaaagc ccgaccaatg tgttggctaa tatgaaagcg
    19141 atcggcgacg attcgggcat tcggaaaaca ctctttcacc aatgtgcgat agggtgtata
    19201 gaaatctgaa accactagac gcacttgttc acggactttt atagggtagc gcaagaaata
    19261 gtcgcgtaaa ggattgagtt gccgattttc cacaatatca atcagttgat gggtcttgcc
    19321 gtccatcatg acaaagctca tggctcccga gacatttttc actgatttga attcatcgaa
    19381 acacaccact tctggtaaca gctggctcaa agaaatggtt ttaggccgaa ggctgcgaag
    19441 tattcgaatg acagtggtcg gagaaatgtg cttcatacgt gcgatcaaag acatagaaag
    19501 aggttcgctt aatagctcaa gaatggcttg tttgactctg cgagcaatgg agcagcgacg
    19561 atcactaact gaatcttctg ctaaaaaagt ctttccacag tgtttacatt tgaagcgctg
    19621 tttgttaatc cgcagaatgg tcttgtagtt actgacatca ttcaataaga tggatacttt
    19681 tttccagccc tatttaatga tcgtttgttc attttgatag tggcgatgaa agcattcctc
    19741 cggttgatag gtcaatgtgc catcaaaagc aaaacatgtt tcgtcattga tgcgctcttt
    19801 gcgaaaggca tcctcatgaa aggtaagatt taggtctaga atatctagta actctttggt
    19861 aaactctgaa taggacatct tgaaacacta ctttgaatgg tttttgtcga ctttattcta
    19921 aaggatttta aggtgtctgt ttgcgtttat tagaaaaaag aaaaagtatt ggcaacagaa
    19981 ggcgtcacca acactagata ttatagatcc cttattttct tcgcttcaaa ttgtcaagga
    20041 gtcatcataa attttgtatg gattcttttg tttgggtagt agtcttctaa ataatcttgg
    20101 attaacacct tcatctctat tttactttta tatttgttgg agtcgattaa ttctcatttg
    20161 attgatcgat gaaacgcttc aattactgca ttgtcaacag gagtcccagt ttggctcact
    20221 gaatgtgtga tgtggtggtc gttcaacagc tcttgataaa taaaagaccg atgctggcta
    20281 cctctatcgg aatgaattac cgtaggcaat tctccttaat aaatttgtaa tggacggacg
    20341 acaatctctt tttttatgtg tgaatctacc atatagtaac gtagaatacg agttgctaag
    20401 tcaatatagg tggacaaata gaggcgaccg tcattacatg gaatgtaagt aatatccatc
    20461 acccaaacag catcaatttg gttctgttca aattatcgat tcaacatttt tttaccattt
    20521 ctttgattgt tttttctcta ccatgagaag atttgcgtcg atgaaatcct cttgtgcata
    20581 aattcatttc acgcataaga acagctacaa cacgtttatt gatttcgatt ccttcatcgt
    20641 aaagtttttg agtgatccct ggagatccgt atcgatcttt gtgttcgtag aacactcgtc
    20701 ttcctctttt agtcgtttat tttcctgttc aagaatgtag aaatctgctt tatcaggtaa
    20761 tctttttcct tgtccagcaa aagcattttt cccgtatcga cgatattctg aaacccatcg
    20821 ggaaattgtt ggacgagaga tattgtattc ttcagcaatt ttcttggtag ttactttttt
    20881 ctcaaggata tcctgtgaaa tctttagttt aaatttacga tcatatgttt ttctcaatag
    20941 agttcattcc ttccggtaac gtaactgata gtcaagaaaa gtgtatcata gcccaactta
    21001 gtatcagggt ttgtcaacta aactgtggaa gttgatagat aagagttttt aacaaccaaa
    21061 attctcttga ctatttttga aatcagacaa attttgattg gacacatagt tgaataaatc
    21121 taccgtcgtt acggaaggta aatcgcatgc ttttcaattc tagaggagaa gtcctcgttg
    21181 aagtaccata gcccagttct ggattcgacc tcctgcccac ttcatacgta aataaagtaa
    21241 ttttaggagt gagactgtga caaaagttat ttttaagcta aaaacgaatt aaaaaacgtt
    21301 gataattaaa atcattcgtt ttagattcta tgaatcatta tagaacgctg taaaatcgat
    21361 actttataat tataaagaag atagtttcaa atttattgtt cgaaatttga aactatcttt
    21421 ttacttatgt cacagactcc cttagttgag ttattcttta atttcgaatt tcgagatagc
    21481 tagatatatt gcaagcatac attcttgata acaatcttga tcatattttc cagttctcca
    21541 ggattgctta tgaatcaaag agctaaatct tttgagaatt gcctcaacag cttcttcatt
    21601 tccagccttt gctaaaatga aatcttcttt taaagaattc ataaatctac cttcttccca
    21661 tggacttata atctatttct ttgggaagga ggagaacgag caaagaagca tacaaaatta
    21721 gttattatgc agatattaaa ccagcatttt ttgaattttt ttgtaaagtc gatgttttaa
    21781 atttgtcgca ccctgtcttg taatccccag aacctttcca atttctttat cagttttatc
    21841 aaagataaat ttttcgataa gaaaaatttg ttcaggttct ttcaacaaag gaaggatttt
    21901 tgctaatttt atatcttcaa caaggagagt cacatttaaa acattaatcg gttgtttaaa
    21961 ttttatagta tctttagtaa acaaatatgg tgggagttga tcaagttgtt catgtttttg
    22021 aatttcttct tgttttttat aataagtatt agcggtgttc aaaatgacct tttcaaagaa
    22081 tcgaatcaac tgggcattta cgcgttcgtc gttatctgac atattgcaca cctcctccat
    22141 taagatttaa agggaaaaga ggcaaaaaac acgaaaagaa gctaatgcaa ttatgctgcg
    22201 ctgcgaataa cttctataag ctcacatgca ttgataggac tgctgatgtt tattttcaaa
    22261 aatgtttttt tagttgataa tggatagtta tctttatact tagaaaagaa aattcatata
    22321 tcttcttaaa tatcaaacat gtccttatgg ctaagaaaat gtcttgagct ttttacgtat
    22381 aataaatctt ttctaaaacc tccttttgga taatattctt attcgtgtat agattgtatt
    22441 ttttatttct tcccccttca taattaacaa ctagaaaaga gttcgaatag acacgtattt
    22501 gaacgaaaat ttttattgga ttcccaaatt ggaatattta gaaacgaaaa attcctatta
    22561 tctgtatagt gcttagataa taacggatca taataattat tgtctttgaa ctagatatat
    22621 gtaaatagta ttcatcatga tgaaaaatga tgagttctcg gtgataaaat gtacttttta
    22681 cggtggaata tacatgaaag cgataagtgg atattttata atgaagtaag ttagcttatt
    22741 ttgacagagg aatagtattt tagataacgt ataaaatact atttaatgat gtagaaagga
    22801 aagagagaaa caaaagtgtt ttcagataaa gaagtcttat taaagtctct tcatgtttgt
    22861 ttaaagttac ctatcgtggt ttttaattcc gaattcagta ttataaaaga gtatcgctca
    22921 gatagaacta cttatttttt ttatgattat aaaaagttac taactgataa tattaaaaaa
    22981 actaaagatt tccatttctt tactggtgat tttaatgaga tgtttcttct atacatgttt
    23041 aaaaccagat attacttatt tggtccattt agagcaaata atattgataa agtttttttt
    23101 aaactaaaaa tgaacaattt gaatgttgca atggctgata gagaacgact ctataattca
    23161 ttgcaaaatt tgactttgta ttctttagga gacattcgag atattctgat tttagttcat
    23221 tattttttta ctggaaaaat agaagatcta ttccatgaac cgttaattga atatacagaa
    23281 aatctaagta aaactatcga gcaaatcaaa atagataatc tgttatcaca aaattacgat
    23341 ccagaaatat atctgtttct ttatgaaaat aaaatactgg aatatgttaa aaatggagat
    23401 attcgaaatt tagaaaacat ggtttttaat ctgagtaatg gaataattcc aagtgttagt
    23461 ggagatacga ttcggtctga aaaaaattat tctatcattg tttttgaaaa gttagcacaa
    23521 acgtctataa cattaggaat ggatataata gaagcgtatc aaagtagaga tgctttgata
    23581 caagaaaacg aattagctgt atcgttacct gaggtcttaa aagtgaggga ttctgggatt
    23641 gtttattata ctaaggaaat cggaaaaact aagatagagc atctttctcc cttaatttct
    23701 tctgtcgttc aattcatcgg cttaaatatc tataaaagaa ttactgtaaa ggaaatagct
    23761 aattattttt ctgtaagtga aactaaatta agagaaagct ttaagaatga aatgcatatt
    23821 acgatttata attatatctc taagcgaaaa atttctacgg ctaaaataat gttgaaatca
    23881 aaccatacta tcagtgaagt ttctttaggt ttaggatttt cagattcttc acacttttcg
    23941 agagtattca aaaagtacgc aggtgtatct cctaagcaat atcaattagg tttagtggac
    24001 aatttcaaca acattagctg agaggtttta ttttattatg agactatatc atttacgtag
    24061 tttggaggag ttgaggaaat tggattttaa caaaaaattt ttttgggaaa tttctgattt
    24121 gagttgtttc gtagaatctg agcgtctaag taatggtaat aatagtgtgt taaatgaata
    24181 tgacaaagta gtaattaata aagtaaaaag tttatgtgaa gaagctagag aatctatcag
    24241 tcatattaat ggtagcaatt ttaaacaaac attatttaat ctgattaagc tagatgctaa
    24301 aatatcaagt tatttattct ttttgataca tgatgaattt atggattatc aaaaattgga
    24361 tcagttaatt gaaagagaaa gctgggaaga ttattacgtg ggtctaactt tttcagaaaa
    24421 gttaaacaac tacaagttaa tagattataa gtatttgagt gaaagcaatt aattattcat
    24481 gtagagtact agacacttta aatatggaca attcaattat aaagaaaaag aatcaataat
    24541 ttaatgaggc tgtgacaaat gtcatttttt gtttcgctaa aaacgagtga aaaaatgttg
    24601 ataactccaa tcattcgttt aagattctag gaatcattca gaaatgctgt gaaaccgata
    24661 ctttataatt ataaagaagg tgatttcaaa ttccgaagaa ggaatttgaa gtcacctttt
    24721 tacttatgtc acagtctcat tcagtaatgc gggataaggc tccttattcc gttatttgaa
    24781 tactctgaag tttaatctaa gaaagggtaa tattttgaaa acatgcttca tcgcatagaa
    24841 atgaacttaa tttcagaaag aatacataca tatcttttta tatgttttca gctgctgaat
    24901 ggttaaaaag cacaaatatc cgaaaaaaac atgaagaaat gtactttttt tgttgtaatg
    24961 ttcatgaaat tctctaagta aattagttaa cataaggtta gtaagattcc tattctgtga
    25021 ataatacgta tcagatttat cttttattct tactaggaaa gtaattatta agggagttga
    25081 tttgaataat ggttagcaag aataataaga gagtatttct agaaaaaaca aagaaacgag
    25141 tattgaagta cagtatcaaa aaattaagtg ttggggttgc atctgttttg attggtgttg
    25201 gtcttgtctt gggaacaact gaactagtta aagcacaaga tgaaatttct ccaagcagcc
    25261 cacttgaaac agcgataagc tccgtacaag taggtgacaa agtagcttcg gggaatactt
    25321 ttcaggagaa tcctggttat acgaaaaatt ataacttttc ggatttacaa tttagtcctc
    25381 aagaactaac tggagacaca ctaaaaggca atacaattgg atttgaagtt tacggaaaac
    25441 ataatattgc agcatcaact aaaaactggg aaatccgtct tcaattagat gaacgattag
    25501 ctaaatatgt agaaaaaatt caggtcgatc caaagaaagg aattggatct tctagacgga
    25561 cctttgtaag aattaatgat tcgctgggta gacctacaaa tatttggaag gtcaattata
    25621 ttcgtgcaag tgatggatta tttgctgggg cagaaacaac cgatacgcaa accgctccta
    25681 atggggtaat tacgtttgaa aagagcctag atgaaatttt taaagagata ggcatagaca
    25741 atctcaagac cgatcgttta atgtatcgaa tctacttggt aagtcatcaa gacgatgata
    25801 aaattgtacc gggtattgat agtacgggct actttttaac agattcagat gatttctata
    25861 atagcttaga tgtatctgaa aataatcctg accagtttaa acatggatca gtaagtgcaa
    25921 aatatgagaa acctaatact caaacaaaag atggttcagg atccacaggt gctaatggag
    25981 ctataatctt agatcataag ttaacgaaaa attataattt ctcatattca tcttccgcaa
    26041 agggcacgcc ttggtatgct aattacaaaa ttgatgaacg attagttcca tatgtagcgg
    26101 gtatacagat gcacatggtt caggctgaca aagtaacata tgatgtttcg tttgaatccg
    26161 gaacaaaagt agctgattta gcaatcgagc gacgggaagg tcatgaaaat tatggcatag
    26221 gttcaataac taataatgat ttaactaaac ttatcgattt tgctaatgca agtccacgtc
    26281 cagtcgttat tcgatatgtt ttacaattga ctaagccatt agatgaaatc ttagaagata
    26341 tgaaagcaac agcacaagtt gaagaaaata aaccatttgg tgaagatttc atctttgatt
    26401 cttggttgtc ggatacgaat aaaaaattaa tccagaacac ttatggaaca ggttattatt
    26461 atttgcaaga tattgatggt gatggaaacc ctgacgataa agaagagagc ggagacacga
    26521 atccatatat cgggaaacct gaattagaag aagtatatga tgttgacaca acagttaagg
    26581 ggaaagtatt catccacgag ttagcgggaa caggtcacaa agcccaactt gttgataaag
    26641 aaggtactgt attagcagaa aaaactatcg ctccaaatga aaaagatggg gctccaattt
    26701 cagatactgt agaatttgaa tttacgggtg tagattcaag taaattaatc gcgaaagatg
    26761 aattaaaaat ccaaatcgtt tctccaggtt ttgataaacc agaagaaggt tcaaccgtta
    26821 ttaaggaatc accaaaagcg gttgataaac aaaccgtggt agttggattt aaaccagatg
    26881 ctaaagaatc aattcggaat aataaaaact tacctgaaga tgcagagtat tcatggaaaa
    26941 cagagcctga tacttctaac gttactgata gtacgaaagg tattgtaact gttaagatcg
    27001 gaaatcgaac tttcgacgtg gatgtagagt ttgctgtaaa agcttctcaa gctatggaaa
    27061 atgatgcaac atacgtacct ataacaacaa ctccagaaac gacagttcaa agtggaaaac
    27121 ctacatttga taaaccagat gttcctttag ctaaagatgc cttttcaatt tcagatgtct
    27181 ataataagga cttcggtaat gcaagtgttg atgcaaacac tggtattgtt acattcactc
    27241 cagctaaagg tgtaggagaa tcggagccga ttactggaac aattcctatt aaaattgttt
    27301 accaagatgg ttctgtaggc acgaccgatt tagcagtaac tgtaagtaaa gatatttatg
    27361 aaaatccagg agaaaacatt cctgcaggct accacaaagt aaccttcacc gcagg
//
LOCUS       DACBZK010000034        26027 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.034, whole genome shotgun sequence.
ACCESSION   DACBZK010000034 DACBZK010000000
VERSION     DACBZK010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.034"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(43..681)
                     /gene="plsY"
                     /locus_tag="IVD66_001526"
     CDS             complement(43..681)
                     /gene="plsY"
                     /locus_tag="IVD66_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HAP6145749.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            808..1242
                     /locus_tag="IVD66_001527"
     CDS             808..1242
                     /locus_tag="IVD66_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HAP6145750.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            1408..3453
                     /gene="parE"
                     /locus_tag="IVD66_001528"
     CDS             1408..3453
                     /gene="parE"
                     /locus_tag="IVD66_001528"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HAP6145751.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            3465..5915
                     /gene="parC"
                     /locus_tag="IVD66_001529"
     CDS             3465..5915
                     /gene="parC"
                     /locus_tag="IVD66_001529"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HAP6145752.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDRSIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            6192..8423
                     /gene="pflB"
                     /locus_tag="IVD66_001530"
     CDS             6192..8423
                     /gene="pflB"
                     /locus_tag="IVD66_001530"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HAP6145753.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            8667..9428
                     /gene="pflA"
                     /locus_tag="IVD66_001531"
     CDS             8667..9428
                     /gene="pflA"
                     /locus_tag="IVD66_001531"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HAP6145754.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            9513..10439
                     /locus_tag="IVD66_001532"
     CDS             9513..10439
                     /locus_tag="IVD66_001532"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HAP6145755.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            10621..11514
                     /locus_tag="IVD66_001533"
     CDS             10621..11514
                     /locus_tag="IVD66_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HAP6145756.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            11648..11773
                     /locus_tag="IVD66_001534"
     CDS             11648..11773
                     /locus_tag="IVD66_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6145757.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(11907..12539)
                     /locus_tag="IVD66_001535"
     CDS             complement(11907..12539)
                     /locus_tag="IVD66_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145758.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(12687..13229)
                     /locus_tag="IVD66_001536"
     CDS             complement(12687..13229)
                     /locus_tag="IVD66_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HAP6145759.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            13364..13753
                     /locus_tag="IVD66_001537"
     CDS             13364..13753
                     /locus_tag="IVD66_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145760.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            13757..14521
                     /locus_tag="IVD66_001538"
     CDS             13757..14521
                     /locus_tag="IVD66_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP6145761.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPNIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            14650..15597
                     /locus_tag="IVD66_001539"
     CDS             14650..15597
                     /locus_tag="IVD66_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6145762.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            15727..16467
                     /locus_tag="IVD66_001540"
     CDS             15727..16467
                     /locus_tag="IVD66_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145763.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(16758..17426)
                     /locus_tag="IVD66_001541"
     CDS             complement(16758..17426)
                     /locus_tag="IVD66_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP6145764.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            17560..17847
                     /locus_tag="IVD66_001542"
     CDS             17560..17847
                     /locus_tag="IVD66_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145765.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            18263..19801
                     /locus_tag="IVD66_001543"
     CDS             18263..19801
                     /locus_tag="IVD66_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HAP6145766.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            19798..20763
                     /locus_tag="IVD66_001544"
     CDS             19798..20763
                     /locus_tag="IVD66_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6145767.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            20750..22072
                     /locus_tag="IVD66_001545"
     CDS             20750..22072
                     /locus_tag="IVD66_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP6145768.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      22135..22239
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            22313..23056
                     /locus_tag="IVD66_001546"
     CDS             22313..23056
                     /locus_tag="IVD66_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6145769.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            23071..24063
                     /locus_tag="IVD66_001547"
     CDS             23071..24063
                     /locus_tag="IVD66_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6145770.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            24075..24812
                     /locus_tag="IVD66_001548"
     CDS             24075..24812
                     /locus_tag="IVD66_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6145771.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            24802..25524
                     /locus_tag="IVD66_001549"
     CDS             24802..25524
                     /locus_tag="IVD66_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAP6145772.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(25608..>26027)
                     /locus_tag="IVD66_001550"
     CDS             complement(25608..>26027)
                     /locus_tag="IVD66_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAP6145773.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         8955 a         4425 c         5428 g         7219 t
ORIGIN      
        1 atttgtcaca ctcccgtttt atctctttgg aatgaaaaag tatcaggatt ttttcttgct
       61 gctattcaaa ccaaacggga ttcgactttc agtatggttt ctgatacgct tgatattgtc
      121 tttatgccga taaaagataa aggaagaaac taaaaaggca atgatcgtca gtaaccaatt
      181 gggcttagcc aaaatcacag gagctacata aggaaggacg atcgtagata aagtgatcaa
      241 tactgcactg atcatactgc tcaaactcac catacttgta caaaataaac taacgataaa
      301 gatgatacaa gaataaacaa aaaatacagg attaaatcct aaaagcattc ctgcacttgt
      361 cgcaacagct tttcctcctt tgaacccagc aaaaatcgga aatgtatggc caagaatggc
      421 gcatacccca aaccaaagag ggttaatccc agaaaggtgg aagatcatcg gcaaacaagt
      481 agccaatgta ccttttaaaa tatccataag caggacaaca atcccggctg ttttgcctaa
      541 tacacgaaat gtattggtcg ttccagtatt accgctcccg tgttgtcgga tatctttttt
      601 gaaaaacaat ttgccaatcc agacaccgga aggaatagaa cctaaaagat atgctaaaat
      661 aagtaataag atcaatttca ttttttaccc tctttcaagt tgaaaactat cctttatttt
      721 agcatgaata ggtaacagga acaattgaaa aaatgaaaga tacaagtata atagatggaa
      781 taaaaagaaa agcaaggggt ggcagaaatg tctgtaaaaa atccaacaca agaaacgatt
      841 ttcaactatt tggaagaagc aaaaaatatt gccgtcgtag gcttgagcaa taaaccagaa
      901 cgaacaagtt acatggttgc acaggtattg caagacaatg gatataaaat cataccagta
      961 aatccattat tggctggtga agaaattcta ggcgagaaag tctatgcgaa tttgacagaa
     1021 atcgatgatc caatcgatat cgtagatgta tttagacgga gtgaattttt acctgaaata
     1081 gcaggtgatt ttttgaaaac tgatgctaaa gtgttctggg cacaattagg gattgaaaac
     1141 aaagaagcag ctgagatgct aagaaaagca ggacgtacag atatcgtaat ggatcgttgt
     1201 attaagattg aacttggtaa gttgaaagaa aaccaaaaat aaaaatgacc acaaagaaga
     1261 gatgatcgat agaggggaat gtcgaaaaag cggttaggag ataattaaaa ttgatttctc
     1321 gtctaccctc ttttttttca cgaccttttc tagtatgata atcgtggtgc ggttttgccg
     1381 caaagtatta ttgaaggagc gtttgccttg gcaaaaaaag taaacaacga atacaatgac
     1441 tcgtccatcc aagtattgga aggattagag gcagttagaa aaagaccagg gatgtacatt
     1501 ggatccactg acagccgagg cttgcatcat ttagtctatg aaatcgtcga taatgcagtt
     1561 gacgaagcat tatcaggtta tggcagtgag attgatgtga ccatccatga agacaatagt
     1621 ataactgttg cagatagcgg acgtgggatg cctgtaggaa tgcatgcttc cggaatacca
     1681 acagttgaag tgatttttac tgtgctgcat gctggcggaa agtttggtca aggagggtac
     1741 aaaacttctg gtggactgca cggtgtagga gccagtgtgg taaatgcctt atcgaaatgg
     1801 ctaattgtaa cgatcgttag agatggcgta gagtatcagc agaaatttaa aaacggcggt
     1861 aaacctgacg gtactttgaa aaagatagga aaaacaaaaa aagcaaacgg gacgactgtc
     1921 cattttttac cagatgatac aatattcagt acaacgaaat tttcatatga aattttagcc
     1981 gaacggttaa gagaatctgc ctttcttcta aaaggcgtta aaatctctct ttctgatctt
     2041 cgtggagaag aaccagtcaa ggaaattttt cattacgaag aaggaatcaa agaatttgtt
     2101 gattatctga atgaagaaaa agatacattg acaccagttg tttatttttc aggagaaaaa
     2161 gaaggtatcg aagtagaggt cgcttatcaa tacaatgacg gttattcaga aaatgtttta
     2221 tcttttgtca ataacgttcg gacaaaagat gggggaaccc atgaagctgg tatgaaagcg
     2281 gcgatgacga aatcttataa tgaatatgcg agaaaagttg gtttgctgaa agaacgggac
     2341 aagaatctgg aaggtagtga tttcagagaa gggttagctg ctgtactttc tatccgtgta
     2401 cctgaaaatc ttctgcaatt tgaagggcaa acaaaagaaa aacttggtac gccagttgct
     2461 cgtaccgtag tagataacgt catcagtgaa caaatgggct tttatttgca ggaaaatagc
     2521 gaaatgagcc agatgttggt ccgtaaagca atcaaagcca gagaagcgag agaagcagca
     2581 cgtaaagcca gagaagaaag ccgaaatggg aagaagcgta aaaaaggcga atctcttctt
     2641 tcaggaaaat tgacacccgc acaatcccga aaccctaaga aaaatgaatt gtatttagtc
     2701 gaaggggatt ctgctggcgg atctgctaaa caaggaagag acagaaagtt ccaagcaatt
     2761 ctacctttac gaggaaaagt catcaatacc gaaaaagcta aaatgcaaga tatcttgaaa
     2821 aatgaagaaa tcaatacgat gatctatacg attggtgcag gagtcggtcc tgagttttct
     2881 atcgaagact gtaattacga caaagtaatc atcatgaccg atgcggatac agacggcgcc
     2941 catattcaag tattactgct tactttcttt tatcgttata tgaaaccgct gattgaagct
     3001 gggaaagtat atatcgcgtt accgccttta tataaagtat ccaaaggaca aggaaagaag
     3061 caagtcattg aatatgcgtg gacagatgac gaattggcag caatgattaa aaaagtcggc
     3121 aaaggatata tgctgcagcg atataaagga cttggagaga tgaatgcgga acaattgtgg
     3181 gaaacaacga tggatccgac ttcccgtacg ttgatccgcg tccgtatcga tgatgctgcg
     3241 caagctgaac gtcgagtaac cacactgatg ggtgacaaag tagaacctcg aagaaaatgg
     3301 atcgaaaatc acgtgcaatt tacgctcgaa gaagatggca gtatcttaga taaaaaagag
     3361 gatactgaaa tctctccttc agtttctaat gatttattag atgaagaacg agcagataaa
     3421 aatgaaaaca atcagttatt tgaagtagaa taggaggtca cctgatggaa aatcgacaag
     3481 aagtacaaga attaacttta gaagaagtga tgggtgaccg cttcggacgt tattccaaat
     3541 atattatcca agaacgtgca ctgcctgata tccgtgatgg attgaagcca gtgcaacgcc
     3601 ggatattatt tgccatgaac aaagatggca atacgtatga caaaggattc cgtaaatcag
     3661 caaaatctgt cggaaatatc atggggaatt atcatcctca tggtgaccgc agtatttatg
     3721 aagcgatggt ccgcatgagc caagactgga agttgcggga agtactgatc gaaatgcacg
     3781 ggaataacgg gagtatggac ggtgatccac ctgctgcgat gcgttatact gaagccagat
     3841 tatccaagtt aagtggagag atgctagcag atatcgagaa agaaacagtc gatctcgtgt
     3901 ggaattttga tgatacagaa aaagaaccaa cagtccttcc agctcgatac ccaaaccttc
     3961 tcgtcaatgg atcgacaggt atatctgctg gatatgcaac agaaatcccg actcataact
     4021 tagctgaagt gatcgatggc acaatctata tgatcgatca tccacaagcg agccttgaaa
     4081 aattgatgga atatattcct ggacctgact ttccaacagg agggatcttg caaggaaaag
     4141 atgaaatcaa aaaagcttat gaaacaggac gaggaaaagt tattcttcgt tcgaaaacaa
     4201 agatagaggc aatgaagggt aataaacagc aaatcgtgat cacagaaatc ccatatgaag
     4261 taaataaagc gaccttggtg aaaaaaatgg atgagatccg tttgaataag aaaatcgatg
     4321 gaatagctga agtacgagat gaaagtgata gaacaggtct gcaaattgtc gtcgaattga
     4381 aaaaagacgc caatgctcaa ggaattttga attatttgtt caaaaacact gagctacaga
     4441 tcaattacaa tttcaatatg gtcgctatcg accatatgac tccgcatcaa gttggactga
     4501 aagacatttt aagaagttat atcgagcatc gaaagcaagt cataacaaaa cgtagtcaat
     4561 tcgatttagc caaagctcaa aaaagacagc atatcgtaga aggattgatg aaagctttat
     4621 cgattctgga tgaagtaatc gcaacgattc gtgaaagtaa agacaaaaaa gacgccaaaa
     4681 agaatttagt cgacgtcttt caatttacag aagaacaagc agaagcaatt gtcacattgc
     4741 aattataccg tttgacgaac acggatatca cagagcttca aaaggaatcc gaaagcttga
     4801 ttgcgcaaat cacagagttg aataaaatcc tttcaaatga caaagagctt ttctctgtta
     4861 tgaaaaaaga attgcgagaa gtgaaaaaaa attattcttc cgctcgtcta acgacaatcg
     4921 aagacgaaat cgaagaaatc aaaattgata cgcaagtctt agtggcacaa gaagacgtaa
     4981 ttgtcagtgt gacgcgagaa ggctatgtga agcgaacaag ccttcgttct tatagtgctt
     5041 ccaaaccaga agaaatcggg atgcgagaag gcgactactt gctatactca ggtgaattga
     5101 gtacattgga ccatgttctt ctgatcacaa ataaagcaaa tgtgatctac cgccctgtcc
     5161 atgaactacc cgatttgaaa tggaaagatg ctggtgagca catttctcaa acaatctcca
     5221 atctgtctgt agacgaatcg attttagctg ttttcccata tcaaaaaatt caagcagaga
     5281 aaacatttgt attcatcagc aagaatggat tgatcaagca aacacgaatg acagagttcg
     5341 aaccatggcg cacctataag agccgtccgc tcagctgtat gaagctaaag gcggaagaag
     5401 atgaactgat tgctgtgtat ctgaaagaag atcagccagg cttagatgtt ttcttagtaa
     5461 cgcatcaagg aatgggtttg cgctatcctt taacagatgt tcccgttgtt ggagcaaagg
     5521 cagctggagt gaagtctatg aatttgaaag atggagatag gattatcaac gggctgcttg
     5581 tgttagcaga aggtgatacg ccgatcgtaa tcgttactca gcgaggagct gttaaacgca
     5641 tgcttgctca agaaatcagc caaacttcac gtgcgaagcg gggagtgacg gtcatgcgtg
     5701 agctgaaaaa aaatccgcac cgtattatct atatgtcgga aggaagatca aaagaaataa
     5761 ccttgatgaa tcaaaaaggg cagcagttaa cgattgaccc aactgatttc cctataggtg
     5821 atcgaacatc gaatggatca tttgcgatgg atgagaaaaa aggtggagaa gtcatcgaag
     5881 ttatcgatgc tcctgagatt ttcatcgagt cgtaactgtt gtagtatttt aatgaagaga
     5941 cgccatctgt attaatacag gtggcgtctc tttttcattc atttttaata aatccttata
     6001 cgtttgcaaa aaaagatgaa agtgttcaca atgcttaaat gttggtatgt caacgttgat
     6061 ttaaatatat gtaaataaaa cataaaaatt gttaaataaa aaacaagaaa acccttgcaa
     6121 agatagggtg ctgtgttata ctaatcacgt aaaaactgtt acataaaaca gaaatttagg
     6181 aggtccatac aatggagcaa tggaatggat ttaaaggtac caaatggaaa gaaggcgtag
     6241 acactagaga ctttattcaa aataactaca ctgaatatcg cggtgatgac agctttttgg
     6301 aaggcccaac agaagcaaca gaaaaattat gggatgaatt gcaaaagtta aatgatatcc
     6361 aattcgagcg taacggtgtc tatgatatgg acacagaaat cgtatcaact attacttcac
     6421 acgatgcagg ctatttggat aaagatttgg aaaaaatcgt cggtctacag acagacaaac
     6481 ctttgaaaca agcattcatg ccgttcggcg gaatcaatat ggctaacaat gcgctaaaaa
     6541 gcaatggcta tacaccaaac gatgaattga cacatatttt cactgactgg cgcaaaacac
     6601 ataatcaagg tgtatttgac gcttatactg ctgaaatgcg tgctgctcgt aaaaacaaaa
     6661 tcattacagg gcttccagac gcttacggtc gcggacgtat catcggtgac tatcgtcgtg
     6721 tggcattgta tggaatcgac tatttgatgg aacaaaagaa aaaagatcat gatatgactg
     6781 gttatcatac aatgagtgaa gaagtgattc gtttacgtga agaaatcact gaacaatatc
     6841 gtgcattagc gcaaatgaaa gaaatggctg cgaaatatgg ctatgatatt tctaaaccag
     6901 ctgcaaatgc aaaagaagct gtccaatggc tatacttcgg atatttagca gcaatcaaat
     6961 cacaaaatgg tgctgcgatg tcaatcggac gtatctcagc attccttgat atctatatcc
     7021 aacgtgattt ggataatgga gtaatcacag aaaaagaagc acaagaattg atcgaccact
     7081 tagtaatgaa attacgtatg gtcaaattcg cgcgtacacc tgaatataac caattattct
     7141 caggattccc tatctgggct actttatcca ttgcaggtat gggattagat ggtcgttcat
     7201 tagttacaaa gaatgatttc cgtctgcttc atacattaac aaatatggga ccttcaccag
     7261 aaccaaactt gactgttttg tattctgaac accttccaga aggattcaga acatatgcta
     7321 gcagaatcgc tatcgaaagt tcttcgattc aattcgaaaa tgataatcag cttcgtgaac
     7381 aatggggttc tgatgattgt gcgattgctt gctgtgtatc aggaacagtt gtcggaaaag
     7441 acatgcaatt ctttggcgct cgtgctaact tggctaaaac actattatat gccatcaatg
     7501 gcggagtcga tgaagtgact ggcgcccaag ttggaccaga atatcgtcca atcacatcag
     7561 aaatactaga ctttgaagaa gtgaaacata acttcatgaa tatgatggat tggttagcag
     7621 aactatatgt caatacgttg aacatcattc attatatgca tgataaatat tcttatgaag
     7681 cagctcagct ggctttgatg gattctgact tgcaacgcac atttgctaca ggtattgctg
     7741 ggatctctca tgcggcagac agcttgtcag cgatcaaata tgcaaaagta aaagcaatcc
     7801 gtaatgaaaa aggaatagca gttgattttg aagtggatgg cgacttccct aaatacggaa
     7861 atgatgatga ccgtgcagat gaattagttt catggatctt ggaatacttc atgggacaaa
     7921 tcaaacgtca taaaacttac cgcaactcaa aaccaacaac ttcattattg acgattactt
     7981 caaatgttgt ttacggtaaa aatacaggaa atactcctga tggccgtgaa gctggaaaac
     8041 cacttgcgcc aggagcaaat ccaagttaca atgcggaaca aagtgggtta ttagctagcc
     8101 tgaactcaac agctaaaatg aattacggct gtgcattgga tggaatttca aatacccaaa
     8161 caatcaatcc ttcaggtctt ggaaaagaac aagatacaag aatcgaaaac ttgcgtaatg
     8221 tcttagatgg atacttctca aaaggagctt atcatttgaa tgtcaatgta ttcagtaatg
     8281 atttattgcg tgatgcaatg gaaaatccaa tgaaatatcc gaacttgacg atccgggtat
     8341 ctggttatgc agttaaattc cgtgacttga caagagaaca acaattagat gtcttgatga
     8401 gaacttcaca cgacagaatg taaaaagttc gtgaaaaaag tttttcgact tagcgtcgaa
     8461 aggacgttga atagccatcg catcaaaatc gaataatcag tatgcttatt tgaaagaaac
     8521 gatttacagg ggcaggactt gtatgttccg tccctgtaaa ttttacacat aacgaagcgg
     8581 caattgcgaa aaattttgtt cagaaagctt cgcttcgaca gctaacttgt acttaaaatg
     8641 aaatcaaaga aaagatgtga acttaaatgg aagaaaaaac aatcggctat gttcattcta
     8701 tcgaaacttt cggttcagta gacggacctg gactgcgctt tgtcgtgttt atgcaaggat
     8761 gccgcatgcg ttgccaattt tgtcacaatc cagatacttg gaatattggc ggagggaaag
     8821 aatacacagc agatgaactt ttagataaag cagaacgctt cagaccttac tggggagata
     8881 aaggtggtat tactgttagt ggtggagaac ctctattgca gatcgatttt ttgatcgaac
     8941 tatttaaaaa agcaaaagag cggaagatgc atactacatt ggatacatgc ggaaaacctt
     9001 ttacgtatga agaacctttc ttttcacgtt ttcaagaatt gatgaagtat acagatttac
     9061 tgttatttga catcaaacac atcgataatg aagagcataa aaaactaacg cattgggaca
     9121 atgaaaatat tttagaaatg gctcaatatt tgtcaaaaat caacaaaccg gtttggattc
     9181 gccatgtact agttcctgag cgaagtgatt atgatgaata tttgatccga ctagacaact
     9241 ttattcaaac cttgtcaaat gtagacagag tagagattct tccttatcat acgatgggaa
     9301 aatacaagtg ggaaacactt ggtttgaaat atccattaga agggatcgaa ccacctacaa
     9361 aagaacgtgt cgaaaatgct aaacgattgc ttcatacaga agagtataca aaatatttaa
     9421 cgcgataggt cgcatcggaa agaagataag tattgcttct ttccgttttt ttgctattat
     9481 taaataggag aaatcacaaa ggagcgaatg acatgtcaaa aattttagtt tttggtcacc
     9541 aaaatccaga tacagatgca atcggggcag ccattgcgtt ttcacacttg caaaatgaat
     9601 taggtaaaga aacagaagca gttgctctag gtacacctaa tgaagaaaca caatacgcat
     9661 tagaccactt tcagctatct gcaccacgag tagtagagtc agctaaagca gaaaatgcag
     9721 atgtcatgct tgtggatcat aatgaattcc aacaaagtat ttcagatatc agcgaagtaa
     9781 atattttagc tgtagtagac caccatcgta ttgcaaactt tgaaacagct aatccattgt
     9841 actatcgtgc agaaccagtt ggatgtacaa gtacgattat tttaaaacta tataaagaaa
     9901 accaagtaac aattcctaaa gaaatcgcag gaatcatgct ctcagctatc atttcagata
     9961 cattgttgtt caaatcacca acatgtacgc ctgaagatga agcagctgca aaagaacttg
    10021 cagcaatcgc tgaagtcgat ctaaacactt atggacttga aatgttgaaa gcaggaacaa
    10081 atctaagtga taaatcagct gcggttcttc ttgatttgga tgcaaaaagt ttcccaatgg
    10141 gcagttccaa cgttcgtatc gctcaagtca atacagtgga ccttaatgaa gtgatggatc
    10201 gacaagcaga gctagaagca gcaatggaag atgaaatgaa agcaaatggc tacgatctgt
    10261 tcgtattagt tgtcacaaac atcttagaca gtgattcaga attacttgtt gctggtaaag
    10321 gaaaagaaaa agtagaagaa gctttccaaa caactttgac caacaaccgt gctttgctta
    10381 aaggtgtcgt ttcacgtaaa aaacaagtcg tacctcaatt gacggctgta tttagctaat
    10441 caaatggtag tatgaagcat tcaaaatgaa tggataagcg attgatataa aaagaaacat
    10501 agaacatact aaaggccgaa gaaatggagg agaataacag tcaattatga ctcttgttct
    10561 tcctcctttt tacgtaaaag ccttttaagt aaaataaaac ggatagaaaa gagaacatat
    10621 atgaactatt attcaaaaaa taaggaaaac ttttatcaaa aactgaccga tgatccgctt
    10681 ttttcttcat tgaccgatta tctatatgaa catcgagaac aagaaacgat tctaagagaa
    10741 ttgaaaaaag aattttcgca aaataaattt tcccattttc ttgatttatt gatcgatgca
    10801 ggattaatca agagggaaga acgaagatat catttgaact ttccaatatt tgatcctaaa
    10861 gattacttgc aacaagccac ttcggctgct gaaaccatag ctgaacaatt gaagagactc
    10921 tctgttgatg aacaaaaatt agcgatggga gaagttattt gggcgtattg tttcgaagat
    10981 gaacggaaag aagcgtattt ttatggagta agaaacagcc gagagacaga attgctgagg
    11041 acaactgcag gaaatgagaa gtaccgtttt atcacacttt cctctataga acacttcccg
    11101 cttactttgg ctaattactt ttttgtacag aagaatcagc ttcctgtaac gaaggcattc
    11161 aaagaattag ccgaacttat tggagacgta aatgaatcgt acttttttga tcaaatagaa
    11221 gttatcgttg acaggatacg taagaataaa tataaaaatc gccggcctag tattttccat
    11281 cagtctctac ttgtgacgaa tactataaag gaagaagaat cattcacatt agaattacct
    11341 attgtcgaaa aaaacaattt tgagattgaa ttaccaacat tggatccttc attgacaatg
    11401 gaggaaatgg cctttcttaa acgacaaatc ttttctgagc tgagcaagaa atttataccg
    11461 catgcatttt cttatatcaa agaatatgga acagttttag tgagtaaaac ctaagagagc
    11521 agtaagcaaa aattatactg actcttgcag gaggagcctt tctcttcctt tatggttaaa
    11581 agaattattt gagtattttg cctatctacc acctattaga ttcactacat ggtctggaaa
    11641 caaaggaatg caaaaaaatg gtgagaaatg tggaatgaca aaggaagtag tgataagaaa
    11701 agttagattt ttaaataatc aatattatga ttcagtcaag tatggcattt tatgggaaga
    11761 actagctgat tagattagga agtccatttg ataatccaga atcactaaga aacgaatggc
    11821 gagtcattaa taatttatcc aatcttgggt tattctttta gattgaagtg tttaaaacta
    11881 aaaaagcatt tatgaagtcg taatagtcag gcttcaaaat gctttttatt ttgtttgttt
    11941 tttctttgcc acataaatac acctagactg acgatgaaga gcatatccaa cagatttcct
    12001 gcgacttgga tcgtcgaagg gttggtcagt ggcattaaag caaggacaaa aaaggaaaac
    12061 aagctgtaaa taaaacaggt gacaggaact aatcgaaaga agagcggaca tttcaattgg
    12121 ctaaaaatga gtgaaaaaat aaaataagta aaaatggata aaatcacgac taaaccattc
    12181 atgataaaga agaaaagcgt attgtgatta aacgaataaa aaagaattgc taaaaaagaa
    12241 aacgttttaa atgcaatcaa tacgcttgaa gcttcgttta acgtaccagg atgtcgatga
    12301 aaaaaatagg caccgaaata aacagaaaac agtaagccgc aaagagaaga caaaatcaaa
    12361 aaaaacggat tttcttcggc ttctgtgata tcagaatgat ccaaaagcaa ccagcctaat
    12421 gcactagaag gcgcatgtga ggtcttaagg tatgaataac atagaaaaaa taagatcgtc
    12481 aaagttgcaa aaaaagagcc taaatgtaaa aaattagtgg ttctacgttg aatttccata
    12541 atatctccaa attaaattga taagtatata aagtataata acaaattgat gagtatatgt
    12601 cgatgttttt taatcaaaat aataaataaa aactgtctaa catttaaaat ttaatttaga
    12661 tattagacag tttttaagtt tgtgagttat tttccttgtc gttttctcac ttttttagtc
    12721 cagaaaccac ctgaaatata ttttggctca taagaaatga taaaagcacg ctcttcgatt
    12781 tctttgatca ggcgatacag ttcacgttcg ctttttctag gagaaagtat ttcgagaact
    12841 agccgctcac cttccagccc cattgcagaa gtctgtgtca caccataacc gtgttctctc
    12901 agtatacccg gcaaactttt atcttctgcg ctatttgctg gcaaaatcgt tgtgaccatg
    12961 atgtatccta atgccaattt gtcttcaatc aaaattccga cactgatacc tactgcgtaa
    13021 cctaacgcat agacaaataa attcagtgga ttatctaaac gatctaaaac aagggataag
    13081 ccgacgatat aaatcgtgat ctcgaccata ctgacaagtg gagcaatcag tcgatagcct
    13141 ttcattgtca acatgaaacg taacgtgttc agagtgatat aagcaaaatt aatgaggaag
    13201 atcatcccca acatttttgg atcaatcatt tgtaaaactc ctttcattta tataacaaca
    13261 atatcaaaaa aaatcgtaag tgaagaaaaa ttgaaacttt atacatacaa aaaaatgata
    13321 aaatgattat aatagaatta taaagatagg ttaggtgatt aaaatgaaaa cggtcaatcg
    13381 tgtgttttgt gccagccacg tgctaagtct ccttctcagt atatacttag gtgtctattc
    13441 gattcaacag ccaattgagg tagagaacat tgtttttcag atgtcgctga cagatggttt
    13501 aattttaagc gtttttttct ttttgatact gtttattggt aatattttcg gtagcgttgc
    13561 cagttttttg aatttttcta tttatccact cctttcgcta gcattaggag tggtgggact
    13621 ttgttctctg tgcttatttc ccgagccatt cagtcctgca tttatattat ttggtacact
    13681 gaacctgttc cagacaactg ttggagcatg gttgctatgg cgatcaggaa atttaatgaa
    13741 aataggtgag taacaattga atccaattat attgaaacgt tctgtccatc atattccagt
    13801 gttagaagtt gttctgaaag aattaagaga ggaacgtatt cccgttgtca tctattatca
    13861 cggatggcag acaagtaagg agttagtttt gacgcaagga agaaaaattg cgcagcaggg
    13921 cattcgtgtg atcctgccag atgcgatgaa tcatggggag cgcaaacagc cggtttcttc
    13981 tattccatcc tatacatttt gggatagtat ctacggaaat ctgtttgaat ttgacacact
    14041 tatcaagcat ttagaaaaaa gaggtcttct acatgatcag cttgcagttg gcggggtttc
    14101 gatgggggga atgacaacat gcgccttgtt ggctaaacat cctaatatag tagcgggcgt
    14161 gtgtttgatg ggttcccctg cacctttgga atatggaaaa gaaatcgtaa ggcgcgcatc
    14221 ggaatataat tatgtcgtac caaaagacta ttttgatttg atttcatggg ttaagagcta
    14281 tgatttgtca ttgcagccgg aaaagttagc tggacgtcct ctgttctttt ggcatggaca
    14341 agctgacgaa aaaatccctt atatacaaac ggaacgattt gtagaaaaaa atcggcataa
    14401 gtcttacgga aaagaaattg tttttcgttc ctcaaaaaca cagcgacata tggtacaaat
    14461 accactaatg gaagaagctt ccactttttt agcaaaaaat ttgataaaaa agtataaata
    14521 attgaaacgg aaaatcactc atgacgatag aggattttcc gttttttatt ttgggctata
    14581 ataaactctg ttaggaaaat ttggtataat tgatagtaag aatgacaaca tgttagaaag
    14641 gaagagagca tgcccacttt agcagatgtt gcaaaacgtg ccaatgtttc aaaaatgacg
    14701 gtctctcgag tcatcaatca tccggaacag gtgactgacg aattgaaaga gttagttttc
    14761 tcagcaatgg ctgaactgga ttaccgtcca aatattgctg caaaagcact tgtcacgaat
    14821 cggtcgcaga tcatcaaatt atttatactg gaagaaatcg acacaactga gccctattac
    14881 atgaatttgc tgatgggaat cgctaaacgg atcggtaaag cgcattattc tctccaatta
    14941 gttacaaatg atgccttcga cgtcggttct tgtgatggat acatcatcac aggtgtcaga
    15001 aaaaaagact tcgattggat cgaccgtttg gaaaaaccag ttgtcttgtt tggggaaaat
    15061 tctgaaggat atgattatgt agacagcgat aatgaatatg gtacagcaaa agcaacgcaa
    15121 tatgccttag aaagagatta tcaaacgatt atttatatcg gtatcgaagt ggacgagcct
    15181 tttgaaattt caagggaaac tggttattta tctgtgatga aggaagttga tcttcctagt
    15241 aaaatcttgc ggtttccaaa tcattcgaca gaagtagaaa gatatatgac agaaaactgg
    15301 gcagatttta cagataaaac ttgttttgta tgtagttcag atcggctagc actaggagca
    15361 gtaagaggga ttataaatgc tggaggacac ttgcccgaag aatttggtgt gattggattt
    15421 gatggggtat ttttagacca aatcagttca cctaaattga caacgatcaa gcaagatatt
    15481 atacgtatgg gtgaagtatg tggagaaatg ttgttaaaaa aaatagaaga aaaaggggcg
    15541 agtcaaggtt atcgtcgttt ttttcctgaa ctagttatca gagagacaac gaattaagtc
    15601 ttattactat atatatattt atgaaattca tcgctatttt cttaaaataa tcagcgcatt
    15661 gctactgaaa acaatgaatc tgtgctatta ttgagaaaag ttccattttt gagaaggatg
    15721 gtttgaatga aagaaatcag acgaaaacat ttccgttttc ctgcgtacga tgatgagtta
    15781 ggcgtaaaat taaccaacga caagaagcga gtattatttg acggacaaga agatcttttg
    15841 actgaacaga atcagtcccc gtttgaacag atgaaagaat ttcatttcac gaacacgaac
    15901 accgagaaaa tccgtcgcaa gcgtcgtgca acaaatggat tgaagtcagc tccgcgtaag
    15961 gaaaatttgg aaaagcataa aggaaaatta ccggattata ccggccatta ccaatcagaa
    16021 atcacatcga caggacgaaa aaaacttttt ggtgattcct ctcgttctgt cagacaaagt
    16081 gaaacaagga cagagtccaa gcatactaca cgaaacgcat ctgttgacac gaaggtgcgg
    16141 gagcgttctt attttgttcc taaatatgta cccgcatcga ttatcccaga ccctagagaa
    16201 agcaaaattt ctgaggatca tttaatcgaa tcgatgaaaa aaacggatga ctcttatctg
    16261 ttgttcgata cagaaccgac gccgtatcaa gaaaaaagaa atggtgagcc gtctgtacga
    16321 acattcaatc gaacaaaaac gttagaggaa acaaagcagt cagaagaaaa aaaatcgaaa
    16381 aaaagccatg gtatcttaga acgctcatta caaggattga tcgatgatca aggaaactct
    16441 ttgggagaaa atagctattt taaataagtg atatacaaat ttatattcgg ctacagttgg
    16501 aaaggaaacg ctgcggcgtt tccttatttt atactctatc cgaaagttta tatcgtatcc
    16561 tcaaattttt ttgagtttaa gcgaattttt tctcccaata agtaagaaaa taatggcaaa
    16621 ataaaaaaac aaactatttt cgcagatcgt ttgcaaaaat agtttatttt tttataaaga
    16681 agattttact gaataatatc attttagttt acataatgat atttctgtaa attaaataaa
    16741 gtagtgaaaa ataagaatca gtgctctaac tgttcaagag gatcaagtgg ttcaaatgtt
    16801 tctgtagtct gttttgcttc caattggggc aaaacagatc caatttccag atacttcact
    16861 ttattcaatg tataagatag aatagaacag ctaagtaatg tatacagaaa atgtgtgaga
    16921 tccaaataaa gcaaggagac aactaaaata ccaaaagtaa tcaagaaaag acttttgcca
    16981 atcttaatat gaaaatattt ttcaatggct tgataaatga tatctgttcc gcctgtgctt
    17041 ccgccgaatc gaaagacgag accgcaacca atgccagaaa gaatacctgt catcaaacta
    17101 ttgatcagta gactatctac agcaaaatgt atatgaaggc tctcccataa atgtaaaaag
    17161 aaaactagcg caaatgttcc gacgatcgtc cggagaaaag cgtgttttcc aaaaagaaac
    17221 aatgagataa gcaataaagg taaattaaaa agcagtgaag tgacagaagg agcgaatcca
    17281 aaaagattat gcaaaagcaa agcaatacca gtaaccccac catctgccag cttagatgga
    17341 atattgattc ctgtcacagc taatccgtag attcctgcgc ctaaaatgat tccgcacaat
    17401 tctgtaaata aatttaattt tttcatttct agcctctttt cttttgaaaa ttttcagcaa
    17461 cttctttatt atactgactt atactcttac ttcaagagga aaatgaaaaa aaattatttt
    17521 tggctgtttc tttttattta tcaaataagg agtggaaaaa tgcgagcagc agacttattg
    17581 acaattctta caaaatcacc caaaaaaaca gagtatcaag gagttttttt ggctcaagaa
    17641 caaaaactgg tgcctgtgac aatggtccag ataaataaag caaatcaatt tatcttttta
    17701 tttgaacacg gcaaagcacc acttgctatg aaagacatct ttcttttttt gatgaagaac
    17761 cgtgagaaag ctgtttatta tcagtcaaaa gaagaactca ttcctcttta tggagtgaaa
    17821 gagatagaaa ataaagtggt gatataagta aaaataagaa aacaagacgt ttatgatgtc
    17881 aaaacaacca ttttttacat ttttggcaaa aaagtgtcat gatacagtat aatattcgtt
    17941 gaacaggcca ataaaggtgt tctcccccac gagatttcta ctttattggc tgtttctttt
    18001 tattaaaata aaagttgtgt gtgtaaaaaa gatatagctg attccaagtg acaatttcgt
    18061 atagattttt atggtattcg tagtgaaaaa acgagaacca aaaagttgat ccgactttgt
    18121 tgcttggatt ctttttttgt cagcatattt agaggtattt ttttcttttt tttgttcgtg
    18181 ctgtaaggtt aaggcaagac aagttagttg ggaaaaagga aagaaatgtt tatacttaaa
    18241 gaataacaga aaggaaggtc gcatgaataa ttttatacaa acattaagtg aaagaaaagg
    18301 cgagttgctg gaagctgcat ttcaacatct gtccatttct ctcatttctt tgctgattgc
    18361 agcactgatt gctattcctt tagcgatttg ggcagccaat cataaaaaaa tggcagaagt
    18421 cttattgcag atcacgggtg tgctccaaac gattccttca cttgccttat taggtttact
    18481 tatcccattt gtagggatcg gaactgttcc agcattgatt gcacttgtta tttacgcttt
    18541 gcttccgatt ttccaaaaca cgtatattgg tctagctgaa attgacccgt ctattgaaga
    18601 agcagcggta gcatttggta tgtccagaat gagacgcttg ctgaaagtag agcttcccat
    18661 cgcattacct gtcattatct caggtatccg aactgcctta gttttaatca tcggtacggc
    18721 tactttggca gcattgatcg gagcaggtgg attagggaca tttattttgt taggtattga
    18781 ccgaaataca cctgttttga cattgattgg tgcgatcagt tctgccttgc ttgcaattat
    18841 attcagcgga ctgattcgct ggttgcagca taagaaacct cgatattcca tcattacttt
    18901 agcagcagtg gtgtgtttat ttggcggcgt ttctttatat cagtctgcct tgtttaaaaa
    18961 tgaaaccatc acgattgctg gaaaattagg agcggaacct gaaatcctga tccaaatgta
    19021 taaagaattg attgaagaca acacaaaaac agaagttgaa ttaaaaccga attttggcaa
    19081 gacgagtttt ttgttcaatg cactggatca aggtcaaatc gatatctatc ctgagttcac
    19141 aggtactgtc ctagaaagct tggtgaaggt acctgaagca atgaaaagtg ctgatttgac
    19201 aaaagaaaaa acatatgacg aagcagaaga attattgaat aagcaattcg atatgacatt
    19261 attaaaacca atggcttacc aaaatacgta tgccttggca gtcaagagat cttttgcgaa
    19321 cgaacatcaa cttaaaaaga tttccgattt ggcagctatc tctgatcaga tcaaagcggg
    19381 attcacactg gaatttattg atcgttcaga tggatataaa ggaatccaag aagcatatgg
    19441 cttgaatttt tcaagtgtac aaagcatgga gccaagtttg cgttaccaag caatcaataa
    19501 tggagatgtc aatattgtgg atgcctattc cacagatagc cagctcaagg agtacgatct
    19561 agtgactcta gaagatgatc gagggttatt cccagcttat caaggcgcac cgctgatgaa
    19621 aaaagatttt gctaaagaac atcctgaaat cgttaaagca ctgaataaat taagcggaaa
    19681 aataacagag gatcaaatga ttgatatgaa ttaccaagtc aatgtcgaaa agaaaaagcc
    19741 gacagaagta gcacgaatct tcctgaaaaa tgaaggatta gtaaaggagg aagatcagtg
    19801 actaaattaa tcgagttcaa acatgtgcaa aaaaagtatg atggaaagta tgtcatcgat
    19861 gacctaaatc tggcaatcaa aaaaggagaa atctttgttt tggttggtcc ttccggtagt
    19921 ggaaaaacaa ctactttgaa aatgatcaat ggattatcta aaccatcagc aggagacatc
    19981 tacttcaaag gaaaatcgtt aaatgaatat aatctgcaga aaatgcggtg gaatatggga
    20041 tatgtgctgc agcaaatcgc tttgttcccg accatgacag tcaagcaaaa tattgaagtc
    20101 atccctgaaa tgttaggttg ggaaaagcag aaaagagcag accgtgtaga tgaacttctt
    20161 caaaaagttg gcttatctcc tgatatttat cgagatcgta tgcctagaga gttgtctgga
    20221 ggagaacagc aacggatcgg gatcatccga gctattgctg caagcccaga tgtgattttg
    20281 atggacgagc catttagcgc attagatccg atttcaagaa actcattaca agaattggtt
    20341 ttgtccttac acgaagaatt gggcacgacc atcgttttcg ttacgcacaa tatggaagaa
    20401 gcaatcaagc taggtgatcg tattgcattt atgaaggatg gagaaattat ccaatgtgac
    20461 acaccagagc agttattgat gaatcctaaa aacgactacg ttcggcattt ctttgatgaa
    20521 ccgaaacaga cgaaagagtg gcgagtagaa gatttagtcg tcaatggata tttcttaaat
    20581 gaaataccag aaaatgctcg tcaacaagtt tgctttgata cgcctatgaa agaagtatat
    20641 tcgcttcttt cggtgtatcc aagcattgtg atagtagaaa agcaaagaag tattgggtcg
    20701 ctgacaagta aagaaatctt tgctttttta agtcgagagg aggaaggaaa tgaaaacata
    20761 tgatgcaatc atcatcggtt caggtgtgag cggcttaagt gctgcttatg gattgaaaga
    20821 agcaggtaaa acagtactag tggtcgaaga agatctatgg ggcgggactt gtcctaaccg
    20881 tggatgtgat cctaaaaaag tcttgttaag tgcagtagag gcacgtaatc gggtaaaaca
    20941 attgagtgga aaaggtttta acgagatccc aactgccaac tgggaagaac ttcaaaaatt
    21001 caaacgaaca tttacggatc cagtcccaga aagccgaaaa aaacaattag cagaagctga
    21061 aatcgatcat ctttcaggaa ccgctcgttt tttggatgat tcatctattg aagtcaacga
    21121 agaagtcttc catgcggatt acttagtttt ggcaaccggg caaagaccta cgatcttacc
    21181 agtggaggga aaggaatact tgaaaactag tgcagacttt ttatcattgc ctgtactgcc
    21241 taaagaaatc atttttatcg gtggtggtta tattgctttt gagctagcta cgattgccaa
    21301 tgctgcaggg agcaaagtaa ccattgtcca tcataatcaa cggccattaa aagaatttga
    21361 ggcgtctttg gtagaggaag ccgtccatca aatggaagca tctggcattc agtttgcttt
    21421 tggtgttgaa acccaaaaga tcatttcaga aggtactcgc tatcgtttag tcggaaaaga
    21481 gacggaatta gtagcagata tgattttttg tgcgactggg agacagccga atacagaatc
    21541 tttagcactt gagcaagcga atatcgtctt tgataaacac ggaattgcag tcaatgatta
    21601 tctgcaaacg agcaatccaa aaatttttgc gtgtggagat attgtttcaa ggaaaacccc
    21661 aaaattgaca ccagtcgcca cttttgaagg aaattatgta gctaagcgga taacggatgc
    21721 aacaagcgaa cctatcaaat atccgattat acctacgatc gtctacgcca gtcctaaact
    21781 tgctgaagta ggagttacaa aaagtcacgc ctcttcgtca gatcaagtgg tagagatgga
    21841 tcttaccagt tggttcacct atcatcgtgt caatgaacca gttgctaagg ctgaattgac
    21901 ctttgaccag caaaattatt tgattggtgc tgcagtgatt agcgagcaag cagacgaatt
    21961 gatcgatgat ttgacactcg tcatcaatca aaaattgact aaaaaagagt tggatagcta
    22021 tatcatgggg tatccgacat tggcaagtga tctctcctat ttattgaaat aatcagcatg
    22081 ataactaaag cgcttgttgc tttttccttc ttgtgctaca ctttaaaaaa tgaatacctg
    22141 tttctgggga tgtcgtagac gacatgagag taagttgtga acttagaccc attgaacctg
    22201 tcagttaata ctggtgaagg gagaaacata gcagacgctt gaagcgggtt actatgtcgt
    22261 gcccatttca agcgtttttt gttattcata ttagaagaaa ggaggtaaca aaatgaagaa
    22321 aaatctttat ccagcagtca gtatggcatt cattttaatt atttggcaga ttgttgtcat
    22381 agtttggaaa atacctgcct ttattttacc cggacctgct gctgtatttt ctgcattagc
    22441 ggcagatgca caagtattac tttcccattc tgtcacgaca ttaaatgaag cagtgcttgg
    22501 tttggtaata gctagcgttc tttcttttat tactgccttg gcaatggatt attggaagtt
    22561 tttagaaatg tctttttatc cgttactagt gatttcacaa atgttgccaa tcatggtgtt
    22621 agggccatta cttaccctat ggtttggttt cggtatgctt ccaaaagtga tccttgttgt
    22681 cttgataagc tattttccga tcgtagtttc tttttcggat acattgagga aagtatcaaa
    22741 agagcaaatc atctttttga aaacgatggg ggcagataca gggaagattt atcgaatata
    22801 taaaatacca gcgggtttat ccggcttctt ttccggttta aaagtggctg ctacttattg
    22861 tgtcagcgga gcagtcgttg gagaatggct aagcgctcaa gcaggcttag ggtattacat
    22921 gatacgcgta aaaaacagct accagatcga taaagttttt gctgcgatca tttgtgtcat
    22981 tctattgagt ttattgctga atggcgcttg ttcattattg aaaaaagggt attatcgtat
    23041 gctttatatt ttttaagaga aggggatcaa atgaaaaaat tatggctttt attaccgcta
    23101 ctgttgcttt tatccgcttg tggcactgca aaagaaacaa gtagcaaaca agaaataaag
    23161 gatttgaaaa aagtgacact tgttttggat tatgtaccga atactaatca tactggcatc
    23221 tacctagcaa aagaaaaagg ctattataaa gaggctggtt taaatgtcca aatcatcgaa
    23281 ccaggagata attcgacaag tattggtcta gtaggtgcgg acaaagcaca atttggtgta
    23341 agttatcaag aagatgtcac ttatgctcac gcagatggac agaatatacc agtcaaagca
    23401 attgctacag tgatcaaaca taatacttct ggattcgcca ccctatcaga cagtaacatc
    23461 cattcaccaa aagattttga aggaaaaaca tatgcaggtt ggcaaagtcc aagtgaagaa
    23521 gctgtcttaa aagctgtgat ggaaaaagac ggcggggact tttcaaaact gacaatggta
    23581 ggaagcaatg gagaagggcc agaaagctta ggaaaatcct cagatatcca atggtacttt
    23641 gaaggttggg atatgatcaa agcaaaagaa gcgggtattg aactaaacta tatcccattg
    23701 aaagaattag atgaacggtt agattactat actccggtaa ttattacgaa tgatcaactg
    23761 atcaaaagtg atccagaatt ggtacagtct tttatggatg ccacgaaaaa aggctatcag
    23821 gaagctatta aggatccaaa tgacagtgct aaactgttgc aaaaatatgc aaaagaaaat
    23881 gatcggacgt ttttagaaga atcacaagca ttcttgtcaa aaaattatac ggatgatcct
    23941 gagaattggg gattgatgga agaaaaagtt tggcgcaatt atacagcttt tatgcaggaa
    24001 aacggattga tcaagcaaga tgtaccttcg caagaactat tcactaatca gtttataaaa
    24061 taggagtgat agatatgtca atccaaatca gccacttgaa tgtagtcatt gaaaacctga
    24121 aaatattaga agacatccat ttcactatcc ctaaagatac ctttacatcg attgtcgcgc
    24181 caagcggagc cggtaagtca acattgctga aaactttaac aggagtccag cctatgactt
    24241 ctggaacgat caaagtagac gatcaaaaag taactggtct ccatacagca tttagttata
    24301 tgccgcaaga agatatgtta cttccttggc tgagcgtcta tcaaaacgtt acgttatatc
    24361 aaaaaatcaa tcatctaaca atcaatgaag aacaagtaag ggattatctg gatatctttg
    24421 ggttaaacgg ctatgaacat tttttgccgg aacaattatc tggcgggatg aagcagcgaa
    24481 cggccttgtt acgaacaatc atgaatcctt cttcttactt gcttcttgat gaaccatttg
    24541 gagcgttaga tgctatgacc agagggcaga tgcaagactg gatgttgaag ctgcctaaaa
    24601 aagcaaagcg gactacttta cttgtgacgc atgatatcga agaagcaatt tatttatcag
    24661 acaggattct tgtgctttcc gcccgtccgg cacatgtgat tgctgagatt caagtgcctg
    24721 aaaaacgacg gtcacgtgaa tggctactgc agcaatcaga gttgaagcaa acgatttatc
    24781 agttattggc aggtgaatta gatgttaagt gatgctcatt gtcatttaga tgggagtcag
    24841 agtttagcac tccttcagca ggaacacacg attttgacga tcatcaattg tgattcgcca
    24901 gaagaatgga aggaaaacag acagcttgca gcaagtaaga ctcaagcctt aagttacggt
    24961 atccatcctt ggaaagcaga tagctatacg tttgaacaag ttgagccttt tttgaaaaaa
    25021 gcaaggatca tcggtgaaat agggttagat aatatttgga cgaatgtacc gatgactaca
    25081 caaaaaaaag tatttgagcg acagcttgct tttgcagcca taaatgagaa acctgttgta
    25141 ctgcacacaa aaggatgcga aaaagagatc ttaaattata tccaagctta ccctaatcac
    25201 tatttgatcc attggtattc ttctttggac tatcaacaag actatattga tttaggctgt
    25261 tatttcagca ttggtcttga tttgaaaaag aatccagcag tctggcaact agctaaagca
    25321 gtcccaatcg accacttact tattgaaacg gatggactac atgcagcaga gtgggcttta
    25381 ggggggattt tttcagaaaa agattatgtc tcactgcttg aagaacagtt aaagacaatc
    25441 gctgagatca aagagctatc agttgaagaa gttaaaaaaa atacttatca aaacttggaa
    25501 cgtttcatta gattaggtaa ataaaaaaga gatgtgacac aactagtgtc gcacctcttt
    25561 ttggctttct ttgtataaaa gtaaactgtt tgattaataa atgaatctta gtaccaaccg
    25621 tttgcttccc agaatgcttt cgccgcttcc caagaaccat aacgtgaagt aacatattgt
    25681 tctgctactc tttcttggtt tgcagcagag tagtcaccat ttaagtaaga agaatctaat
    25741 tggtaacgtc cgatgtaacg tccgttcgtt gctgtgtaag aaccgcttga ttctttttgt
    25801 gcgatccatt cttttgcaga gcttgtgctt gctggagtag cagcagtttc tgttacagca
    25861 ggagcaggtt gtgtttcagc aacaggcgct gcttgttttt ccgtttgaac cgtttcttgt
    25921 acaacaggtt gttcagcttg gactggtgct tcttgaacgg ctgcttgagg ttcagcagct
    25981 gcttgtgcag agccttctgt tgggattgtt aattgttgtc ctgagta
//
LOCUS       DACBZK010000035        25694 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.035, whole genome shotgun sequence.
ACCESSION   DACBZK010000035 DACBZK010000000
VERSION     DACBZK010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.035"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            126..3653
                     /locus_tag="IVD66_001551"
     CDS             126..3653
                     /locus_tag="IVD66_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAP6145774.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3650..7372
                     /gene="addA"
                     /locus_tag="IVD66_001552"
     CDS             3650..7372
                     /gene="addA"
                     /locus_tag="IVD66_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HAP6145775.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7441..7782
                     /locus_tag="IVD66_001553"
     CDS             7441..7782
                     /locus_tag="IVD66_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6145776.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8091..9134
                     /gene="pheS"
                     /locus_tag="IVD66_001554"
     CDS             8091..9134
                     /gene="pheS"
                     /locus_tag="IVD66_001554"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HAP6145777.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9139..11559
                     /locus_tag="IVD66_001555"
     CDS             9139..11559
                     /locus_tag="IVD66_001555"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HAP6145778.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11729..12739)
                     /gene="trpS"
                     /locus_tag="IVD66_001556"
     CDS             complement(11729..12739)
                     /gene="trpS"
                     /locus_tag="IVD66_001556"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HAP6145779.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12993..13730
                     /locus_tag="IVD66_001557"
     CDS             12993..13730
                     /locus_tag="IVD66_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP6145780.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13744..14559
                     /locus_tag="IVD66_001558"
     CDS             13744..14559
                     /locus_tag="IVD66_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAP6145781.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14572..15219
                     /locus_tag="IVD66_001559"
     CDS             14572..15219
                     /locus_tag="IVD66_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP6145782.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15235..15891
                     /locus_tag="IVD66_001560"
     CDS             15235..15891
                     /locus_tag="IVD66_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP6145783.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16053..16874
                     /gene="racE"
                     /locus_tag="IVD66_001561"
     CDS             16053..16874
                     /gene="racE"
                     /locus_tag="IVD66_001561"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HAP6145784.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16877..18232
                     /gene="rph"
                     /locus_tag="IVD66_001562"
     CDS             16877..18232
                     /gene="rph"
                     /locus_tag="IVD66_001562"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HAP6145785.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18233..18751
                     /locus_tag="IVD66_001563"
     CDS             18233..18751
                     /locus_tag="IVD66_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAP6145786.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18858..19358
                     /locus_tag="IVD66_001564"
     CDS             18858..19358
                     /locus_tag="IVD66_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP6145787.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19638..20558)
                     /locus_tag="IVD66_001565"
     CDS             complement(19638..20558)
                     /locus_tag="IVD66_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HAP6145788.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20723..21736
                     /locus_tag="IVD66_001566"
     CDS             20723..21736
                     /locus_tag="IVD66_001566"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HAP6145789.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21846..22601)
                     /gene="fabI"
                     /locus_tag="IVD66_001567"
     CDS             complement(21846..22601)
                     /gene="fabI"
                     /locus_tag="IVD66_001567"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HAP6145790.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22821..23261
                     /gene="fabZ"
                     /locus_tag="IVD66_001568"
     CDS             22821..23261
                     /gene="fabZ"
                     /locus_tag="IVD66_001568"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAP6145791.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23376..24137)
                     /locus_tag="IVD66_001569"
     CDS             complement(23376..24137)
                     /locus_tag="IVD66_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP6145792.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24326..25420
                     /locus_tag="IVD66_001570"
     CDS             24326..25420
                     /locus_tag="IVD66_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAP6145793.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            complement(25506..>25694)
                     /locus_tag="IVD66_001571"
     CDS             complement(25506..>25694)
                     /locus_tag="IVD66_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP6145794.1"
                     /translation="NSNGILRRNGLPKSMDFRKVNQTFISSVSNQRNHIPRKSLNYRT
                     PIEIFLSYVQEAFYSSLI"
BASE COUNT         8509 a         4454 c         5416 g         7315 t
ORIGIN      
        1 gtatacttaa aaaagtagaa atatcagaac cttaaaagga tataatttga agaatataga
       61 acaaatgttc agtatttttt gatataataa aggagcaccg tatcatgtgt tgaaggagga
      121 aaagcatgtc tttacaattt attcttggaa acgggaaaaa agatcaccgt caagtcttga
      181 tcgacgaagc atccgcttgg ctcgaccagg atgcaagtaa ccaagtattt ttccttgttc
      241 ccaactacag caaattcgaa caggaacaag aaattttagc ggagatgcga agaagaagcg
      301 gaaaaaaaac tttcagcaca acaaacgttc aagtatttag tttttatcgt ctggcttggt
      361 atttgctgca acagacaact cttcttacag gaaatgaatt atcagaatca ggatctgcaa
      421 tgatcttgcg acagatttta gaaaaaaatg aggaagaatt aacaatcttt cgcggagaaa
      481 tcaataaaag agggtttatt cgtcaattac aagaactcta cagtgaattg cgtacaggaa
      541 atattcaacc agaagacctg atgcttttat ttggtgattc acctaatgca gaagaccagc
      601 aacttaaaat gaaagacttg aagctgattt tttcagctta tgacagcgaa ttgactcaac
      661 gtgcactaac aaatgaagat gcactatcta tactagcaaa ttatatgcag acacaagatt
      721 tcaacaacgt caaatttatt gtcagtggtt tttctcgaat caatggtcaa gagtatcaat
      781 tactgcaggc aatgatggaa aaggggcaat tggttgtcga tttattgctg gatcgtcctt
      841 atacagcgga tcttccagaa gtacttacgc tctttcatga gactggaaag ctttatttcc
      901 gtctttttca aagtgcaaga gaacggaaag tccctatatt agtggaccga tttgcaccag
      961 agcagactcg tccgacagag cttcaactgc tgcaaacaat gtgggaagag acatctagcc
     1021 aaaagaaagc ggcagtacac aaaatagggg gacaagagca tctccatttg tgggaagctg
     1081 aaaatccaac tgaagaagtc cgacaattag ctgttgaaat cagacgacta gtcagtgaag
     1141 aaaactaccg ttatcgtgat atccaagtgc tgacaaaaaa tatgtcttta tatggaaata
     1201 tccttcggcc gatctttcaa gaaatggcaa ttccttttta tatcgatgaa gaacaaatga
     1261 tggaaaatca tccgctgatc gaatggatca acagtctgtt cgctcttgac cgctattctt
     1321 atcggctaag tgatattatg cgttttttca aaactgaatt atttctgtcg acggaagcag
     1381 aaaccgaact tgatgaatgg aaacaagagc gagatgaatt caggaaaaaa ctggacatca
     1441 ctgaaaatgt agcacttgct tacaattatc aaggaactta ttggactcgt gaaaaagact
     1501 ggcagtttgt ggcgtatgat tttgaagcag aacagattga agacgtacag tatttggaag
     1561 aacagtcaaa tacgattaga cgattatttc agaaagctgt accagtattt ttgaaaaaaa
     1621 taaagaaaag caaaacagga caagaggccg caaatgtttt ttatcaattt ttgatccaaa
     1681 gtggcgtaca gcaacaatta ttgttttggc gtaatcagga agtagacaga ggaaacttag
     1741 aagcggcaag aaaccatgag cagacatggg gagcgctgat tgatctgttg gatgaatatg
     1801 tagtaattta tggtgaatcg gcttttgact ggtcactgtt ccaagaaatc attacaagtg
     1861 gtctagaaaa tctaagttat ggtaaaatcc ctaccgcaat cgaccaagtg cgaatcaatc
     1921 gtttggaatt agttcgacca aatcaagctg ccgtcacttt tgcattaggg ttgaatgatc
     1981 aagtgtttcc agaccgaaaa gagacaaaag gattgttgtc cagtgaagaa cgagaagtat
     2041 taaatcaggc cttgccagat ggacagtttt tattcgaccc atcaaaggaa agtatctctt
     2101 ttgagccttt ccaagcctat cttgtttttc tttccggaac agatcgatta tatcttagtt
     2161 atgcacaaag ctatgacaca gatggttcgc tgaagatgtc tccttatttg cgtagaatca
     2221 cagaatattt atctgttccc gtcgagagaa aagagcattt gacgatcgaa agcgacccta
     2281 attgttatgt agggacttac agaagcggaa tcaatacagt caataggatt tatcgattag
     2341 ctttagatga aaaaaaacct gtaccaaagc actggcaaaa gctcaaagaa ttagtactga
     2401 attcgtcatg gcgaaatttt gctttacaga tttttgaaag tcaggaacat ttaaatgttc
     2461 ctgtttcgat gccagaaaaa atggcggaag agctttatgg aaaagagatt tatacttcaa
     2521 tttcacgtat ggagaatttt tataattgtg aatacaaata cttcatgcaa tttggtttga
     2581 aattgaaaga acgaactgtt tatggtctaa ctccagcagc aactggtgat ttttatcatg
     2641 aatcattgga tcgtttcttc aagctactgt tttcaaacca attatcctta gtgaatatgt
     2701 ccgatgcgca gcgtagagac tttactgaaa aagtgctgca ggaagtattc ggagaacttc
     2761 ggtttgagat attggatagt tctgcaagaa tgaactatat ccgctaccag ttaggacaga
     2821 cgattcaaaa agtgacatgg gctttgcaaa aacagagcaa aaatacaggc atgcatcctc
     2881 ttcagacaga gattctattt ggtcagattg ctggagcaaa aggtatcaca ggtctggaat
     2941 taccgttgag taatggtgga aaactccatg ttcgagggaa aatcgatcga atcgatgtag
     3001 cttctgaaca agaagatact tggctaagcg tcgttgatta caaatctagc ggacgttcat
     3061 tcgatgtcac agaagcttat tatggcatgg ctatgcaatt attgacgtat ctggacgtag
     3121 cattgatgga tgcggtacgt ttgactggaa aggcggctgt taaaccagca ggatcatatt
     3181 atttacatgt tcataatcct gtattgacgg agacagatga tgtagagaag aatacattga
     3241 aaaaatttag ttatgatggc gtttttgtcg atgatcccgc tcttttagaa gtactagatc
     3301 attcactgga agcaaaagaa caatcactga tctatccagt gaaaaaaaat gcgaaagatg
     3361 aataccaaaa aggtagtttc agtaaagaca aatttttcac ggaagaagaa ctgcaactat
     3421 tcatggcgca taatcgggaa aatatgcggt tagctggaga tgcgattact tccggagaaa
     3481 tcaaactaaa tccagcttat aaagataaac agcggattgc ctgcgaattt tgtccattca
     3541 gaagcatctg tacgtttgat gtgatgctga aagaaaataa ttaccaccgt ctggagaaaa
     3601 tagataagga agaagcactg cgtagaatat tgaaaaggag tgaagaagag tgaatcaaat
     3661 tcctttaaaa ccgcaaaatg aacgattcac agatgatcag tggcaagcga tttttgatca
     3721 aggagataat ctattagtct ctgcgtctgc cggatcaggt aaaactacag tgcttgttcg
     3781 aagagtgatt gaaaaactaa aaatgggttt tgatatcgat gaattattga ttgtgacatt
     3841 tactgaagct gccgcaagag aaatgaaaga aagaattcaa gaggcattac aagaatccgt
     3901 caatagcgaa agtgaccctg tacgtagaca gcattttact aagcagttag ttttattgcc
     3961 cacagcgaat atctcaacct tacatgcttt ttgcctgaca gttattcgac gttattatta
     4021 cttaattgat attgatccag tctttcgcat gttaacagat gaaacagaaa cgatcttgat
     4081 gaaggaggat gtgtgggacg agctgagaga agcactttat gcagaaaatg atgaacgatt
     4141 tttccaatta acaatgaatt tttctaatga tcgttcagat gacggcttga cgaatctggt
     4201 gttttctctt tatgagtttg cccgtgccaa ccctgacccc caaaaatggc tagaacagtt
     4261 aagcgataat tatcgtttgc ctgaggggct agcgaaatct cgattatatc aaaaacaaat
     4321 ccgtccttta gttttggcag atatatacca atgtgtacag ttatatgaac agatgactca
     4381 gttagcacaa ggtgaaggat tagaaaaaat gcatgagcaa gtagctggag aacaacagca
     4441 gatcaagaat atctatgaag cgttctcgca agatcggtta gaagaagctt atgctggttt
     4501 ggaacaacta actttttcaa cttttaagag cagtcggaaa gcagaattga aagaaatttc
     4561 caatgaagtc aagggcatga gggataaagc aaaaaaactg attcagcaga taagtaaaag
     4621 ttattttcct gtttccccaa gccaaatgga agaattaacg gacaaagcac taccgttagt
     4681 cgaagaaatg acaaaagtca cgcaaagctt catggacggt ttcagtatgc gtaaacggga
     4741 aaaaggtgtg ctggatttca atgatctgga acatttagcg ttgcagattc tcacagaaaa
     4801 aacgaaagat gtatggctgc caagtgaagc ttcaaaacat tatcgaaaaa aattcaaaga
     4861 agtaatggta gatgaatatc aagacgtgaa ccaattacaa gaagccattt tatactggct
     4921 aagagaaccc gatgatacaa aaggaaatat gttcatggtt ggggatgtca aacaatccat
     4981 ctattctttc cgtttagcag atcctagttt atttatcggg aaatacgaga atttctcaaa
     5041 gaaagaaggc ggacgtcgaa tcgttttggc tgagaacttc cgctctagaa aagaagtcct
     5101 ttcttttacg aatcttattt ttgaacaact aatggatcca gcagtgggtc aaatcaatta
     5161 tgacgaagca gccaaactga tccaaggatt ttcagacttt ccagagaatg aacagtttga
     5221 gccggaaatc atgatctatg aaaaagaaca ggaagaatca gagattgaga ttccgacgga
     5281 tgatatactg gaagacaaaa cagaaggcga actttttatg acaggactaa aaattcgtca
     5341 attaattgat tcctccttta tgatttatga taaaaaatca aaaaaaagtc gtccgataga
     5401 gtacaaagac attgttctct tgacacctac aaagaagaac aacttaacga ttttagagat
     5461 tttcaaaaca ttggatattc cattagagat gaatgatgct caaaactatt ttcaagcgac
     5521 agaaattcgc acgatgatct cgctgctaca attaatcgat aatccctatc aagatattcc
     5581 gcttgcggct gtattgcgct caccgatcgt gggtctgatt gaaccagaat tagccagcat
     5641 tcgattagct aaccgtgcac atacttacta tgatgctgtg cttgcttatc aagcatcaaa
     5701 cgaagatgaa ttagcagcta agctggaaca ttttggcaag caactagagc attggcgaga
     5761 acttgctcgc cgttcttcga tcactgactt gttatgggat atctattatg agacgggata
     5821 tctagagtat gtggtcggtc tgccagcagg ggcacagaga caagccaatc tttatgcatt
     5881 ggttgatcgt gccaaagctt acgagcaaag ttctttcaga ggattatacc agttcgtgcg
     5941 tttcattgaa aaaatgcaag aaaaagataa agacttagca gaaccagtca tttcaataga
     6001 agataatgct gttcgcgtta tgacgatcca tgcaagtaaa ggcttggaat tcccagttgt
     6061 atttttgtta gatatgacaa aggagttcaa cttacaagac ttgcgcaatc ggtatgcttt
     6121 tgaagaaaaa cttggagcag gaattcgcta tatggatcct gaaacacgag tgttatatga
     6181 tacgttaccg tttcaagcca tcaaattggc aaagcaaaac aaattgttgt cggaagaaat
     6241 gcgtaaattg tatgtaggat tgactcgggc agaacaaaag cttttcattg tcggttccta
     6301 taaaaataaa gagcaaatga tccaaacgtg gtctgaagca gctgatcatg aggagttagt
     6361 ttttgatcct gcgctacgtt tgaagggcag aagcagcttg atgaattgga ttggttacgg
     6421 attgatccgt catcctgaaa tgcagaaata cttagaggaa gaaatttcga cttctcttct
     6481 tcaacattca aatgcacagt tttctatttc atggatgaat cagcaatcga tcattgaaca
     6541 aagacagttg cttgctgaaa aagaactggt taacttagat cagcagatga aagaagatga
     6601 aactttatta gcagattcgt tacaaaaacg tctggcatat gaatatcctt atcaagcttc
     6661 ttcacaaacc acaagttatc aatctgtatc tgaaatcaaa cgattattcg aagatccaga
     6721 tgatacacaa gaatcacgtt tgactctgga aagcagtcag aacaaagcag catcccgtca
     6781 atttcgttat acgcaagaac aactagcaga accaaaattt ttgcaaaaag atcggcaagt
     6841 gtcagcagct gctgttggaa ctgctacgca tgctttgtta caattactgc cattagagat
     6901 gccaactaca gagagtatcc atcaaaaatt acaggaattg gtaaggaaac ggttagtaga
     6961 cgaaaaagtc gcgaaaaaag tagatgtttc ttctattata tggttctttc aaacagaact
     7021 tggtcaacag ctgattgcca acaaagaaaa cgtaaaacga gaacaacctt tttccatgct
     7081 gcttcctgct gacgaagtat ttcaagacta tccaaatcaa gaagatgaac tattaatcca
     7141 cggaatcgtc gatggatacc tagaagaaaa agatcatctc aatatctatg attttaaaac
     7201 agattttatt ttacatccgg atgatccagc agaaatagat gcaatcgtcc aaaaatatca
     7261 aggacagcta agactttacc aacaagcaat gtcagaagct ttgaataagc cagtagaaaa
     7321 tgttttccta attttgcttc gagtgaaaca aattataaac attaacaaat aattataatt
     7381 gagcaaactt gacttatgtt ttgtaaggat tatgctatac tctgggaaga ggtgagtatg
     7441 atggagctaa cacagacaga attcgtttta tgccctaaat ttgaaaaaac attctctatt
     7501 ttaggaaaaa aatggaacgg attgattatc gatgtactac tcgaaaacgg tccgcaacgc
     7561 tttgttgagc ttgcggcaaa aatcccgatg gtcagtgatc gagtattagt cgaacgcttg
     7621 aaggaattag aaaaagaagg aatagtcact cgaaactttg cctgtagcga aaagagccgt
     7681 tcagaatatc tcttgactga aaaaggagca gacttgcaaa aagcgatgcg tcaaatacaa
     7741 gtttggagcg aaaaatggat cacagaggaa gaatgcggtt gattttgtaa aaaaaatctt
     7801 gtaaactata gtccatacga ataagtaaag aacgatgacg aaaaagagta gtttggctaa
     7861 accagttcag ggagatctgt cgcagactga aagcagatcc tgtgtttgaa aaatgaagtt
     7921 cactttccga gttcgtctga taaaatcaga ccggcaattg tcgttaacga agtaagagtg
     7981 cggtgtaagt catttatccg caaattagga tggtaacgcg aagacctcgt tccttaacag
     8041 gaatgaggtc tttttgtttt gtatttggaa tttaaaggag gaacaagcac atgtctctac
     8101 aagcacaatt agagagcttg aaagaagcaa cgctcgtcaa aatcacagcg gcacaagatt
     8161 taaatgaatt aaatcaaata cgtgttgaaa cgttaggaaa aaaaggaccg atcacagaag
     8221 tattacgtgg gatgaaagat ctaagtccag aagagcgacc aaaagtcgga agtttcgcaa
     8281 atgagatccg agatcttttg acagaagaga tcgagcgaaa aaaacaagta ttagaagaag
     8341 aagcgttaaa tgcagctttg gcaaaagaaa caatagacgt gacactacct ggtagaaaag
     8401 taaaacatgg tacacgtcat atcgtgacac aaatcatgga agaaattgaa gatatttttg
     8461 tgggtatggg ctatcagatc gtagaaggat atgaagtaga atctgatcat tacaatttcg
     8521 aacggatgaa tctgccaaaa gatcatccag caagggacat gcaagatact ttctatattt
     8581 cagacgagat attgattcgg acacatactt caccagtcca agcacggaca atggaaaaac
     8641 atgatttctc taagggtgct ctacgaatga tctcgccagg gaaagtcttc cgcagagata
     8701 cagatgatgc gacccacagt catcagttcc atcaaattga agggctagtt gttgataaaa
     8761 acatcacaat gggcgacctt aaaggaacat tagaagtcgt aatgaaaaaa atgtttgggg
     8821 aagatcgtga aattcgtttg cgtccaagtt atttcccatt tacggaacca tcagtagaag
     8881 tagatgtcag ctgtttcaaa tgtggtggtg ccggttgtaa cgtatgtaaa tacactggat
     8941 ggatcgaaat tttaggagct ggcatggtac acccgaatgt gttgaagatg tcaggaatcg
     9001 atccagaaga atattcaggc tttgctttcg gccttggacc agaccgcgta gctatgttgc
     9061 ggtatggagt gaatgatatc cgtaatttct atcaaaatga cttacgtttc ttaagtcagt
     9121 tcaaggggga gtaagaaaat gttagtttca tataaatggc tcaatcgtta tgtagattta
     9181 tcgaatgtaa caccaaaaga attagcggat aagatgtctg tgacaggaat cgaagtagag
     9241 ggagtaacgg ttccagaaga aggcttgaaa aaaatcgttg tcggtgaagt caaggaatgc
     9301 gtaccacatc cagattctga tcacctttct atttgtcaag tcgatattgg cgaagacgaa
     9361 ctgtctcaaa tcgtttgtgg agcgcctaat gtgaaggttg gaatcaaagt gattgttgca
     9421 cttcctaact cacgtatcgc tggtaatgta aaaatcaaaa aaggaaaaat gcgtggccaa
     9481 gtatcaaatg gcatgatttg ctcattacaa gaaattggct attcagatag tgttataccg
     9541 aaagaatacg ctgaaggtat ctattatatg ccacaagaag ctgtaaatgg cgatccagtt
     9601 tttccttatt tggatatgga tgattcgatt attgaattat ctatcacacc gaatcgtgcg
     9661 gatgcattgt caatgcgtgg cgtagcttat gaagttgggg caatttatcg tcagactcct
     9721 acattcgatg acgaaaagct ggtagaatcc tcacgtcctg ctagcgataa aattcaagtg
     9781 gaagttgaag ataaagaagc agttcctgct tatcaaatca gaatcattga aggagtaaga
     9841 atccagccaa gtcctcaatg gctgcaaaat cttttgatga acgaaggcat tcgtccaatc
     9901 aacaatgtag tagatgtgac gaactatatt ttgcttttat tcggacaacc actacatgca
     9961 tttgactacg acaaattgaa atcaaaagag atctttgtcc gccgtgcaaa agaaaatgaa
    10021 acattagtaa cactagatgg agaatctcgg gaattgacaa ctgacaatct cgtcattact
    10081 aacggcaaag aaccagttgc tttagctggt gtcatgggag ggttagactc agagatcacg
    10141 aatgaaacaa caacagttgc actagaatct gctttatttg atccaatttc gattcgtcgt
    10201 acagcaaaac aatttaattt gcgtagtgaa tcctctgcac gttttgaaaa aggaatcaac
    10261 catgcgactg ttggagaagc cagtgaggtt gctgcagcaa tgatcgtttc tcttgcgggt
    10321 ggggaagttc tacaaggcgc ggtcaaaggc tcagagatca aagcagaaga cgtatcagtg
    10381 aagatttcac ttgaacgcat caatcaatat ttaggaacat ctcttgtcgt taaagaagta
    10441 aatgagattt ttgaagcact tggatttagc tatgaagaaa aggagtatgt ttattccgta
    10501 gtagtaccac caagacgctg ggatatccaa atcgaagcag atattatcga agaagttgct
    10561 cgtatttatg gatacgacca gttgccatct acacttccaa gtggagaaac ggttgctgga
    10621 agcttgtcaa aagaacaaga aactactcgt aaaattcgta caatctttga aggaagcgga
    10681 ttgagcgaag caatcagtta tgcattgaca acagaagaaa aatcaagaca gtttgttata
    10741 aatgaaagta atattacacg tttggactgg ccaatgagcg aagaacgttc tgtattacga
    10801 atgaatttga tcagcggact attagatgat atcagttata acactgcccg aaaaaataca
    10861 gagattgctt tatatgaaat tggtcgggtg ttcttccaag aaaatgatcc acgtacacat
    10921 ctgccgcaag aagtaaaaca tgcagcaatc gctatttctg gtatttggga agaaaaagat
    10981 tggcagacga aagctcaaaa tgtagacttt ttcaccatca agggtctttt agaaaactta
    11041 tttgaacaac taggcatcac tgaagatgtc cattatcaaa cagtgacaga aatgaaggaa
    11101 atgcatcctg gaagaactgc tgcgatttac cttggcgaaa aatttattgg ttttgtcggt
    11161 caagtgcatc caacgattac aaaaagttat gatattccag aaacatatgt tgctgagttt
    11221 gatttatctg ctatagtgga agctgctcaa aaagggatcg ttttcgaagc agtgacaaaa
    11281 ttcccagcag tcagccggga catcgctttg cttgtaaaag aaactgtgac aaatcaggaa
    11341 ttaacagaag ttatccgttc tgctgccgga agatttttaa cagatatcca attatttgat
    11401 gtctatcaag gagaaaacat tgaaaaagga cataaatcca tggcgtatag cctgacattc
    11461 gtcaacccag aagcaacatt gacagatgaa gaaatcaata aagcaatgga aaaagtcgaa
    11521 aaagcgttgg tagaaaacct agaggcaagt attcgctaag aaggaaaata tagtaagtaa
    11581 cgatcaagta gcttttgaag accatacatt tgaaaaaaag atgtgacaca acttcgtcac
    11641 atctcttttt ttgattttaa aaaaggaata gcacagagac gagataaaaa aacaggcctt
    11701 tacagcctgc ttttttagag taaatgaatt aatggaagta attgattccc attgctgatt
    11761 ttacttcaga aagtgtttgt gcagctactt tagcagcttc ttcactacct ttacgtaaga
    11821 tttccataac agctgaagga tctttttcca attcttctcg gcgcgcacgg atcggtgcaa
    11881 attcagcttc caatacatca atgaggtatc gtttgatctt tacatcacca agtccgccgc
    11941 ggcggtaatg agctttcatt tcttcaattg cttctttatc tgttccgaat acatccaagt
    12001 aggtgaagac catattccct tctacttgtc caggatcttg tacatggatg tggtttggat
    12061 cagtatacat actcatgact tttttctgta agacatcggc aggatcggag atataaatac
    12121 cgtttcctaa cgatttactc attttgccat ttccatcgat tccaggtaat ctacccattc
    12181 cttttggtgg gaatacgcct tttggttcca ccaagacttc accatatgta tgattgaagc
    12241 tttgtacgat ttcctgtgtc tgctctagca ttggtttttg atcctcacca acaggtacaa
    12301 gattcgcttt gaatgcagtg atatctgctg cttgagaaac aggatagata aagaatcctg
    12361 taggcacgct ttcaccgaat tttttttgtt cgatttctgt tttgacagtc ggattgcgcc
    12421 gaacgcgtcc tacgctgact aagttcaaat aatacatggt taattcagct aattccggaa
    12481 tttgtgattg gataaataaa gtagattttg caggatctaa tcccacggct aaatagtcta
    12541 aagcaacttg caagacattt gatgaaacct tctcaggatt tttagcatta tctgtcagtg
    12601 cttgcatgtc agcaatcatg acaaacagtt ggttgtcttc atctgcctgc atagccactc
    12661 gggtttttag agaaccgacg taatgcccta aatgcagctt cccagttggt cgatctcccg
    12721 ttaaaataat atttttcaaa aaagacacct ctttacgatt tgtaagtctg agcacttaat
    12781 atcttaccgt ttttcctgaa aagaaacaac agttcctaag gaaaaaacaa ggaaagagga
    12841 taaaataact aatagattag aaatggaaga aatatttatg ggagaataaa cgttctaaga
    12901 aactttacaa attactaaac tatcagatat aatgtatttt attatacatc tttaaaagaa
    12961 atcttactaa ataataatgg gagtgtaatt ctatggcaat gattaaattt gatcacgtgg
    13021 ataaatatta tggcaagttc cacgcattaa aaaatatcaa tctcgaattc gagaaaggag
    13081 aagttgtcgt tgtcattggt ccttctggtt caggaaagag cacgatgctt cgctgtatca
    13141 atggattaga gacgatctct tcaggtaagc tgctgattaa tgatactgac ttgcatgata
    13201 aaaagacaaa actgacagaa gtccgaaaaa acatcggcat ggttttccaa catttcaatt
    13261 tgtacccaaa taaaactgtt ctggaaaaca tcaaattagc accaatcaaa gtgttgaagc
    13321 aagaccaggc aactgcagtc aaaaacgcgg agaaattttt gaaaactgtc aatatgttag
    13381 ataagaaaga ttcttatcct tccatgttat ccgggggaca acagcaacgg gtggcaatcg
    13441 ccagaggttt agcgatgaat cctgagatgc tgctgtttga tgaacctact tctgctttgg
    13501 atccggaaat gattggtgat gtattagacg ttatgaaaaa attggctcat gacggtatgt
    13561 caatgattgt cgtgacacat gaaatgggct ttgccaaaga agtggcggat cgtgttatct
    13621 tcatggctga tggagaagta ttggaagaca gcagaaatgt gagagacttt ttcgaaaatc
    13681 caaatgaagt ccgagcacag caatttatca gtaaagttat caatcattga taggaggaaa
    13741 aagatgcgca ggttaaaaaa aatacgcctg attttccttt taggcattgc ttttcttgca
    13801 ctagccggat gtaaaggaaa tgggttggca aatgaagata ttttagagcg aagcaaatct
    13861 accaatgaaa tcatctgggg tgtcaagtat gatactcgat tatttggaat gatggatatt
    13921 gagagcagaa ctgtacaagg atttgatgta gatattgcaa aagcaatcac taaaaagatc
    13981 cttggtgaca atggaaaaac agaatttgtt gaagtcactt ctaaaactcg gattccatta
    14041 ttgaaaaacg gaaatatcga tgcaattatt gcaacgatga cgatcacaga tgaacgaaaa
    14101 aaacaggttg acttttcaga tgtctatttc gatgctggcc aagctttgtt ggtaaagaaa
    14161 ggaagccaaa tcaaaagtgt agatgatttg aatgcttcta caacggttct agcagtcaaa
    14221 ggttctacat cggctgcgaa tatccgacag catgcaccag atgcaaaaat tttagaatta
    14281 gaaaactatg cagaagcatt tactgcttta caatctggtc agggagacgc gatgactacg
    14341 gataatgcga ttttgttagg gattgcagat gaaaatccag agtatgagtt agttggtgga
    14401 acgtttacta atgagcctta cgggattgcg atcaacaaag ggcaagaaaa cttcttgaaa
    14461 gctgttaacc aagcgctaga ggaaatgcat gcagatggca catacgataa aatctatcaa
    14521 aaatggtttc caaatgaaac tgaaggaaaa gtagagtaag ggggagaggc aatgagcgaa
    14581 ttgatacaaa cttatggacc aatctttgtc gacgggttca agatcacatt gttttcgagt
    14641 gtcttagcac ttgtgtttag tttgattatc ggaacgttaa tggcaatctt ccaattatca
    14701 aagaataaag tagtgagcgc cttagcaaag gcatatgtag aattttttag aaacattcca
    14761 ttattaatca tcgtgatgtt tttttatgtt gtcgtaccga tttattggtt taatctagat
    14821 ggattccaag caggtacgat tggattaacg atctatacat ctgcttttat tgctgaaaca
    14881 gtacgttcag ggattcaaac cgtaccaaaa ggtcaaacag aagcaggact atcttctggt
    14941 tttacctatt cagaaatcat gcgttatatt gttttaccgc aagcattcaa aatcgttatc
    15001 ccgccattag gcaaccaatt tatcaacctc gtaaaaaact catctatttt agcaatcgta
    15061 gctggtttag atttgatgta tcaaggagac ttgatcgcta gtgaaacatt caataccttc
    15121 gatacgtata tcatcgttgg gttattttac ttagttatca cgctaccgtt atcttactta
    15181 atggtttatc ttgagaaaaa atgggcggtt cgttcataga aggaggggaa atacatggat
    15241 tttagcggcg ctttttcatg gatgaatatc cgttttttat tggaaggatt aaaggttact
    15301 gttgaagttt cattgttttc gatcattttt agtttcttga tcggtggtct gacaggtgtg
    15361 attcgttttg cgaatatccc tttcttttcc aaaatccttg gtgtagtgat tgatattata
    15421 cggaatcttc cattattatt gatcattttc ttcacttact ttgccttacc tcaaatcggc
    15481 attcagatga acatcttctg gtccgctgtc gcagcattaa cgatttttga gtcagctatg
    15541 ttgtcggaaa ttttccgagc tggactcaat gctgttccaa aaggacagat ggaagcagga
    15601 ttatcaacgg gactgactta tgtagaatcg atgcgaacga tcgtgttacc gcaagcattt
    15661 aaatcaatga tcccggcaat tgtgagccaa ttgatttcac tgatcaaaga tacttcatta
    15721 gcagtaatca tttctttacc tgaactttct catcaggcac gtattattta tggacagaac
    15781 accaattatg tgcttccgat gttcatcatc atgacactta tgtacttcgt ggtatgttac
    15841 gcgctttctc tgctttccgg ttacttggaa aagagacggt acagttatta atagatgatt
    15901 cttttagcgg ttgtggcaaa ctaaagtcac aaccgctttt cctctttcca ttcgaaaaaa
    15961 agagatttcg attgttttaa gcaagtaaga gcacttgaaa attcacgcta aaaagtacac
    16021 aatagggagg atagaattta ttgaaaaaaa ggatgatacg attgacagat aatcgcccta
    16081 tcggatttat tgattcaggt gtcggcggct tgactgtagt aaaagaagcc ctgaaacaat
    16141 taccgaatga aaatatttta tttgtaggag acacagcacg ctgcccatat ggccctagac
    16201 ccgcggaaca ggtaatccag tatacttggg aaatgacgga ttatctggtg gagcaaggaa
    16261 tcaagatgct ggtgatcgcc tgcaataccg caactgcggt ggctttagaa gaaatcaaag
    16321 ctgctctttc tattccagtc atcggtgtga tccttcccgg tactagagcg gcagtaaaaa
    16381 aaacacaaaa taaacaagtt ggcattatcg gtacgattgg tacggtaaaa agtcaagctt
    16441 atgaaaaagc actgaaagag aaagtaccag aattgactgt gacaagtctt gcttgtccca
    16501 aatttgtttc agttgtcgaa agtaatgaat accattcatc ggtggcgaaa aaaattgtgg
    16561 cagaaacatt agctccttta accactaaaa aaatcgatac attgattttg ggatgcaccc
    16621 attatccatt attacgcccc atcattcaaa atgtaatggg agaaaatgtt caactgatcg
    16681 attctggagc agaaacagta ggtgaagtat ctatgctgtt agattatttc aatttgagca
    16741 attcaccgca aaatggtcgg acattatgcc agttttatac aactggctct gccaaacttt
    16801 tcgaggaaat agctgaagac tggcttggaa tcggacactt aaatgtagaa catatcgaat
    16861 tgggaggaaa ataaggatgc gtcatgacgg gagaaaagcc caagagcttc gcaaactgga
    16921 gcttcaaaca aatgttttca aatatccaga aggatcggta gtgatccgtt ttggtgatac
    16981 aacagttatt tgttctgcaa caatagaaaa ttctgttccc ccttttttga gagaaacagg
    17041 aacaggatgg gtgacagcag aatatagtat gctgcctcga gcaacgagta cgagaaatcg
    17101 tagagaaagc agcaaaggga aactttctgg tagaacaatg gaaatccagc gtcttattgg
    17161 tcgttccttg cgtgcagtag tagacttgga aaaattagga gaacgtagta tcatcgtaga
    17221 ctgcgatgtg atccaagcgg atggcggtac tagaacagca agtatcactg gggcatttgt
    17281 ggcattgaaa ttagccattg aaaaactttt aagagaaaaa gaattgtcag aagatccaat
    17341 aaaagaacat cttgctgcag ttagcgtagg aatcttacca gatgggactt gcgtcacaga
    17401 tttggattac caagaagatt ccgcagcact tgtagacatg aatcttgtaa tgacagaatc
    17461 tggaaaattc gtggagattc aaggaactgg agaagaagca acgtttgatg gtgaacagtt
    17521 gaatgaaatg ctcttttttg gaaaaaacgc gattgaagat ttgatcaaag agcaaaaaca
    17581 tgctttgcta acagagtttg ctcaaaatga tgagcggata gaagaaacaa aaacaatcat
    17641 cattgcgaca agaaatccag gaaaagcaga agagtttcga aatatgttca aagaagcggg
    17701 atatcatgta aaaacattac ttgactatcc tgaattgcca gatgtggaag aaactggcag
    17761 cacatttgaa gaaaatgccc gattaaaagc agaaacgatt gcacaattgc ttgatcagcc
    17821 agtcttagca gatgattcag gtttgaaagt ggatgcttta ggcggtatgc caggaatcta
    17881 ttctgcacgt tttgcagggg aacaaaaaag tgatgcgggg aataacgcca aattattata
    17941 tgaattgaca gatgtgccgg atgaaaaaag aacagcacaa ttccattgta cgttagtatt
    18001 cgcggcaccc aaaaaagaca gccttgtagt agaagcggaa tggcccggtc gagtagcccg
    18061 tataccatct ggcgaaaatg gctttgggta tgatccttta tttatcccag aaggtaagaa
    18121 acaaacagca gcagaattat cgagcgaaga aaaaaacaag atcagtcatc gggctcaagc
    18181 aatgaaaaaa ttgagtgccg agtggaaaca atggctggaa ggagagagat agatgcggta
    18241 tttagtagta agtgataatc atggagacag agatatcctc gttgacttag tagatcgtta
    18301 tcgttctgaa gtggatatct ttttccattg tggtgattcg gaattagaag cttctgaccc
    18361 attatgggat acattccaag tggttcaagg taattgtgat tatggaccag gattcgaaca
    18421 gaaaaaagtg atccaaactg gtcaggatac agtattcatg actcacggtc atttatcgaa
    18481 tgtccgattt ggtttgacac agttagcaat cgaagctcga gctgcaactg ccgatatggt
    18541 gttttttggt catacccatc aaataggctg tgagatggat cagaaaatcc tgtttttgaa
    18601 tcctggtagc atttctcagc ctagaggccc gatccaaatc ccatcatatg ctcttatcga
    18661 aagtttagat gaccaaattt ctgttcaata ctataaccgt gcccatcagg cagttgaaga
    18721 gttggccttt tctttttcga gagagcgctg aataaaaaaa ctctaatttt taataaaaat
    18781 aagctttatt ttatgaattt tgcatccggt ttcggtaaaa tagtagtgtt gaatgaaata
    18841 gaaatggagg ccatcagatg attggaccta tagtaagaga aatgctgctg gaaaatcagg
    18901 aaacgttttt gattcctgca gaaaatgtgg caaatgttat gtatcatcat ccattgtccc
    18961 atggtttact tgtgttatcg aaggtcggtt attccaaaat tcctgtatta ggaaaagatg
    19021 atcactttgt aggactagta agtttatcag atgtggtcaa taaaatgatt gacttgcaaa
    19081 caatcagcat ggacccgtta gaaggactaa cggttgctga tgtgacagaa acagatgttc
    19141 cgacaattga tgaaaattgg gaactagaag aagtactcca tttgttagtc gattcgcctt
    19201 ttttaccggt tgtcacagaa gatcggattt tcaaaggaat cattacaaga aaagagctgc
    19261 ttaaagccgt aaacttcatg gtgcatgaat tagaacgtcg taatatattg tctccgaaaa
    19321 tcgaagaatt aaaagaacaa atcgatatcg tgagctaaag aacgagaaac taaaagataa
    19381 tcaaaaaata agtagaaaaa acagcgtacc agttttgact ttatcttgaa aaagaggctg
    19441 ggacaaaagc gtttaactcc aagaaataag aaggaattca cgaaaattgc ttttcaaatt
    19501 tttgtgaatt tcagcttatt tccgaaggag ttgcttctgc ttccgccgtt tatacgtgtt
    19561 tagagcgtgg gacaaaagtg ttctttactt ttgtcccacg ctctttttag tgagattcgt
    19621 tgcatcgttt gtccaaatta ttttccgaca gcaattggac tgttcggaat cgtgaaacca
    19681 gaagctgtca attctttgac ataggagctc aagaactctt cttttaaggc atattgtttt
    19741 ccgttcaatg cgtagcagac cgtacgaatc gcaaaattgc tgtttccaag atccactaat
    19801 ccaaagatag aaggttcagt ttggagctct tcttggtatt tttcagctaa tgtacgattt
    19861 actcgatcaa tgatctcata gattttgtca tatccttctt caggaacaat ccgaatatct
    19921 aaaagtactt gcatatttgc acgagagaga ttgctgatcg tggtgatgtt tcgattcggg
    19981 atgaaatgga cagtaccatc cgttgctttc agctgaaggg tacggatacc aacagatacg
    20041 acggttcctt caatcgttaa gtttgctagc ttgatgtagt ccccaacatc catctgttgt
    20101 tccatgataa taaaaaatcc ggtaataaca tcactcatga acccttgggc accaagaccg
    20161 attgccacac ctgcaattcc ggcaccagcc aaaagtgatc cgatcggcac accgatagca
    20221 gataaaattg catagataaa aaagaaacca agggtataat gaaaaatagt atttaaaaga
    20281 ctatgtaaag tctttaagcg gctctcgttt agaatggctt ttttagaata ctgattaaaa
    20341 gacttatcaa tcagatattt tcccacacgg tgaagaatcc aaaaaaggac gatcaaaaaa
    20401 atcagatata aacttttttg gataaaggca gccaaaatgg cgtcccaatc aatcccgtcc
    20461 caaaaccgct gaaacgcatt tactttgctg acagcttgat ctgtcaatgt ctcgccagaa
    20521 gagtctgtcg taccggcagt tgctaataat gaaaacataa aatcctcttt tctaaaattt
    20581 gattctttct gtattgtacc aagaagtttt caaaaaagga aatagcaaaa ataactataa
    20641 tgaaggaaaa aagctgaaaa taaaatgaca aataatatgg ataatgataa aatgtggaga
    20701 aaataacgaa ggtggtaagt atatgcaaat cgattggaac aatctaggtt tttcttatat
    20761 caaaactcct tggcgtttta ttgccaaatg gaaagacgga caatgggaag aaggagaatt
    20821 gacagaagat aattacctga cgattcatga aggctctcca gcgcttcatt atggtcagca
    20881 atgttttgaa ggtctaaaag cttatcgtcg aaaagacggc aaggtcaatc tctttcgacc
    20941 tgaacaaaat agtcgacgga tgaatcaaag tgctagacga ttgctgatgc caatggtccc
    21001 tgaaaagatg ttcgttgatg ctgtcaagca agtggtaaaa gcaaatgaag attttgtgcc
    21061 gccctatgga acaggcgcta cattatactt gcgcccttta ctgattgggg tcggtgaaaa
    21121 cattggtgtc catccagctc cagaatattt atttgtcgtc ttctgtacgc cagtaggagc
    21181 gtatttcaaa ggtggactaa aaccaacgaa ttttattgta tctgattacg atcgtgctgc
    21241 tcctaagggg actggtgcag caaaagtcgg cggaaattac gcagcgagtt tacttccagg
    21301 aacagaagca aaagaactgg attactcaga ttgtgtttat cttgatccag ccacacatac
    21361 gaaaatcgaa gaagtaggtg cagcaaattt ctttggaatt acaaaagacg gaaaattcat
    21421 cactccgcaa tcgccctcta tcttaccaag tatcacgaaa tattccttgt tgcagttagc
    21481 tgaagaacga ctaggactgc aagcaattga aggagatatt ttcattgatg atctagatca
    21541 atttgcagaa gctggtgcat gtggtacagc ggctgttatt tctccaatcg gtgggattta
    21601 tcacaataac aatcttcatg tattttatag tgaaacggaa gtaggaccag taacaaaacg
    21661 gttgtatgat gaattgacag gtattcaatt tggagacata gaagcaccag aaggctggat
    21721 tgaagtcgtg gaataatttc aaagtaatga gttgaaaaaa acgtaaaaag aaaaaatcag
    21781 gaagagactt taaaaagttt tttcctgatt tttatatgtt ttactttaaa gaatgcaaca
    21841 aaagtttatg aaagatggac acctttgtca acgtagataa tatcaccgat gattccgctg
    21901 gaaagtgggc tgattaagaa agcacaagca ttaccgactt cttcgatcgt cacaccttgc
    21961 tgatcaggcg tacgagattc agataactgg atcagttttt gatagtcttt aacacctgtg
    22021 acagctaatg ttttgattgc cccagctgag attccattga cccgaattcc tttaggcgag
    22081 aactcagctg ccaaataacg gatagcagct tcaagagaag ctttcgcaat acccatcatg
    22141 ttataattcg ggattgcgcg ttctgaacct agataagtca tgctaacgat cccgctgttt
    22201 ggtgcaagaa acggttgtgc gtattttgat acagcaatta aagagtagct gctgatatct
    22261 tgagctaatt gatagccgtc tctggaaata tcagacacat ttccggacaa ttcttctttg
    22321 ttggcgtaag caactgcatg gacaaggccg tggatctccc cagcatattc accgatggca
    22381 ttcattgctt tttcgatgct ttcgtcgcta gaaacatcac attctacagt gaatgcttct
    22441 tcgccgacca atttgactaa tgattttttc attcgttcat tttggtaagt atagataatt
    22501 tctgcccctt gtttcaacat tgcttcagca caaccccaag caatgctttt tttgttagcg
    22561 acgcccataa tgacgatttt ttttccttct agaaatgaca taatgactct cctttgtttc
    22621 tgataaaaat ttgatagtcg taaaaaaata gagaataata gctaaaataa cttcttgatt
    22681 tcttaattat tagtcaaaat gttttgattg tcaaactatt ttttcttaaa ttaaaaaaag
    22741 attgctaaat atttaggaat atgatacttt gatagtcaaa gtaatgaaaa tggcaattgc
    22801 ctgaaagaag gagtttaatt atgtcttacg tattatctgc tactgaagta atggaattga
    22861 ttcctaatcg ttatcctatt tgttatattg attatgtaga tactttagaa ccaggaaaaa
    22921 agatcgttgc gacaaaaaat gtaacaatca atgaagattt tttccaaggt cactttcctg
    22981 acaatccagt gatgccgggt gcgttgattc tagaaacact ggcacaagca ggttcgatac
    23041 ttatcctaaa atcagaagag tttctaggaa aaagagctta tatcggtggg atcaataagg
    23101 ccaaattccg tcaaaaagtt gttccaggag atgtgctgaa atgtcatttt gaaatcacca
    23161 aaatgaaggg atcagtcggt acagcgttat ctgcagcata tgtagatgat aaaaaagtct
    23221 gtgagtgcga gttcacgttc atcgtcaacc aaaatgcttg actataaaac ctgatatagc
    23281 aaaacaaaag gaagcttact tgctttttat gtaaaaagaa gacgcctgaa tcctagcata
    23341 cgttgtcatc tatgcaggat tcagacgtta tttttttatt tttgttttgc ttcttgcagt
    23401 atattgattt tatcgatttt tacttcttct tttggtttgt ctgaactatc tgtttcgata
    23461 tttgcaatag catccacgac atccattcct tcaatcactt ggccgaagac agtataatgg
    23521 ccatctagtg aaggataacc gccgttttta taagcgtcga tgattgcttg aggatagtcg
    23581 tcttttaaaa gaccatcatg catatcatct gtattttgaa cgataaagaa ctggctgccg
    23641 ttactgttag gatcttgtga gcgagccata gataacgcac ctcttatatt ataaaggtgg
    23701 ttgttgatct ctgtttcaaa tccttctccc caaatgcttt cccctccagt gccatcgcct
    23761 ttaggatcgc caccttggat catgaaatct ttgatgacgc gatggaaagt cagtccgttg
    23821 tagtaaccgt cttttgcatg tgtcataaag ttttcaaccg cttttggtgc gtgttcggga
    23881 aataatttga ttttgattgt gcctttattc gtcaccattt cgaccagatc ttcattttcg
    23941 gcgacatctt tcgtcaattg tggtaattcc aatgcgttca aatcgacgct actggcagtc
    24001 gtgctttccg cagtagatgt actttttgaa ctttctgtag acgaactaga agaagtcgtg
    24061 ttgtttgcag aacaaccagc agcaaacagc aatgctgctg ctaaactaat acttaaaata
    24121 actttatttt tcttcataac tgttcctttc caatttacta ttttgttatc tttaatgata
    24181 acaaaataga gggaaaatac ctacttaaat tattggaatt tatcatttat tttaaaagaa
    24241 aaagaaaagg tgtagaccat ttactttgtg tttgctataa tgtaagtgga tacaaaaacg
    24301 aaaagatgca ggaggaaatg gtaatatggg aaaattagga atctcgattt atccagaacg
    24361 gtcaacattt gaaaaggaca aagcgtactt ggatttagct cataagtatg ggtataaacg
    24421 ggtttttacc agtttgctgc agatcaatga tgataaagaa aaagttcttt cagaatttaa
    24481 agaagtagtt gattacgcga atagcctagg catggaagta atggttgata tcaatccagc
    24541 gttatttgaa cagttggaga tttcttacga tgacttatct tttttccata agatgggtgc
    24601 ctacggggtc cgcttagata tcggattcac aggagcagaa gaagcaaaaa tgacgcgcaa
    24661 tccttttggt atcaaaatcg agatcaatat gagttcgggc acgaattacg ttgacaacat
    24721 catgagttat tcgccaaaca cggataattt attaggttct cataattttt atcctcatcg
    24781 atactctggt ttaggatacg aacactttgt tttttgttca gaaaaattca gaaaatataa
    24841 tttgaatacg atggcattcg tcaattcgca atctgctgag tttggccctt ggcctacgca
    24901 agatggcttg tgcacgctgg aagaccaccg agatcttgaa attgcgacac aagtgaagca
    24961 tttaatcctt acaggattga ttgatgatat ttctattgga aatgcgtacg caagtgaaga
    25021 agaattgaaa gaaatggcag aagcatttaa cgcggattat ccaacattga aagtagatac
    25081 ggaagaaggt attacagaaa acgaacgaat ctgcttgttt gataaccttc atagttatcg
    25141 aggggatcgc tcagaatata tccttcgttc aacgatgact cgtgtatact acaaagataa
    25201 agatttcccg cctcataata cgcgagatat gcatcatggg gatgtactga ttgacaatga
    25261 agggtacggt caatacaaag gagaaacaca aatcgccttg aaggatatga aaaacgacgg
    25321 acgtgtcaat gttgtaggaa gaatctccga tgacgaatta ttcctccttg actttttgaa
    25381 accatggtca agctttaaat taattgaaaa taaaaaatag ataattagtt attgcagaaa
    25441 taatccgcta gaaatagcca gttatttctg cttttttatt ttgttttttt ataggttatg
    25501 atttgtcaaa ttaagctaga ataaaatgct tcttgtacat agctcaaaaa tatttcgatt
    25561 ggtgttctgt aattcaatga ttttcttgga atatgattac gttgattgct gacactggaa
    25621 ataaatgtct gattcacttt tctaaaatcc attgatttcg gcagtccatt acgacgcaga
    25681 atcccgttag aatt
//
LOCUS       DACBZK010000036        24552 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.036, whole genome shotgun sequence.
ACCESSION   DACBZK010000036 DACBZK010000000
VERSION     DACBZK010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24552
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.036"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(129..800)
                     /locus_tag="IVD66_001572"
     CDS             complement(129..800)
                     /locus_tag="IVD66_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145795.1"
                     /translation="MIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGITFIVES
                     LLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWDKILHA
                     VSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLCDQFLG
                     MNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFESYKLE
                     KVKNT"
     gene            complement(793..1287)
                     /locus_tag="IVD66_001573"
     CDS             complement(793..1287)
                     /locus_tag="IVD66_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAP6145796.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(1307..2527)
                     /locus_tag="IVD66_001574"
     CDS             complement(1307..2527)
                     /locus_tag="IVD66_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6145797.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            2674..4509
                     /gene="lepA"
                     /locus_tag="IVD66_001575"
     CDS             2674..4509
                     /gene="lepA"
                     /locus_tag="IVD66_001575"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HAP6145798.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            4706..5617
                     /locus_tag="IVD66_001576"
     CDS             4706..5617
                     /locus_tag="IVD66_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6145799.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGQLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEISKESNRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFNKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            6615..6866
                     /locus_tag="IVD66_001577"
     CDS             6615..6866
                     /locus_tag="IVD66_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145800.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFVESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            6949..7221
                     /locus_tag="IVD66_001578"
     CDS             6949..7221
                     /locus_tag="IVD66_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145801.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            7311..7550
                     /locus_tag="IVD66_001579"
     CDS             7311..7550
                     /locus_tag="IVD66_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145802.1"
                     /translation="MIDISIPEDLKPDPATIGNSGMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMIFGDGEVANKAGIPIGKWTVDFHEAGSFFVL"
     gene            7697..11992
                     /locus_tag="IVD66_001580"
     CDS             7697..11992
                     /locus_tag="IVD66_001580"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HAP6145803.1"
                     /translation="MYAKTKMNWLKALALVALSQFCFLVGTAQAHAEETTATQPTVEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPVT
                     SQPVEETASITTPASETSTPEGEKAAEATPSVKPESSEKQAEEKQRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKLNKESTASIEDQKKKEQDIPKTGTPTLLVTVP
                     TNRSVRVRRATNTAVLGGRKIDWGENIGVTSSPNNPNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALENYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLLNNFDVRATFHNQTHTIKIGETLKVKSGNDFLQRV
                     KGIQKPKGINVSIHGNEAWITVTKEAPEKAKIHFNQIEVLGTPLAYRRPGAQTIGILN
                     PFEPGDSVVNLTILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KNMNGKVQAEIKDLDPGKYVLKEIKAPKGYALSDETIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKIANKDLVDSTNPDNKPKLAGIEISLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKERYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVT
                     FTLYNGKGQAIGKYTTDQNGEILVKGLVANNYYFTENVPLESFQPNTGKQAFTITFRQ
                     NAPDDGETLLVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQEGKEITSILTFIADKANGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAVHVDINDDNQSVRVNNPTVHTTAVFEDGLTIADPTGLFTLNDTVEINE
                     ILPGKAYLVKGILMDKATGEALLVHGQPVESAVGFIAKAENETVIVPFTFDLTGLNGR
                     EMVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLIVGKTYTVNGVLMDKVTEKPVLVDGKEVSSTLTFVAETTDGTVNLDFILD
                     AHALRSKEVVVFEDLFREGVLLASHADITDKDQTIKIVSPTITTKATNANGGKEILAL
                     PNQKVVEWVQVNGLAIGQIYKLIVQGYLTPDGTPFEGTHAEKVFMADKEMMEFLFEFI
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQFVEAPKPPQPVK
                     PNEPQPVKEVKQAAMVPMLPKTGSEDNVLWIMIGMIFVLAAGLIGYDLYKVRD"
     gene            12708..12953
                     /locus_tag="IVD66_001581"
     CDS             12708..12953
                     /locus_tag="IVD66_001581"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145804.1"
                     /translation="MEEIFFCMMVEFLFVSIGFLIMGEAIMIYLFPFDSKDECIFSSI
                     IIFFILACVWILAREIYHQFVLEDGKGIITWFLQKRK"
     gene            12970..13164
                     /locus_tag="IVD66_001582"
     CDS             12970..13164
                     /locus_tag="IVD66_001582"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145805.1"
                     /translation="MEKKNINICFLSGKECTYEECTDISVHERDGMLIVDMSPSDEPF
                     VVKHYFPLCNIESFRIDCEF"
     gene            13181..13546
                     /locus_tag="IVD66_001583"
     CDS             13181..13546
                     /locus_tag="IVD66_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145806.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIEEVL"
     gene            13548..14000
                     /locus_tag="IVD66_001584"
     CDS             13548..14000
                     /locus_tag="IVD66_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145807.1"
                     /translation="MGLKFPNNYDITEALDETCIGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNSNPKQSQEKGLDQKQPSADSKEKEKK"
     gene            14066..14422
                     /locus_tag="IVD66_001585"
     CDS             14066..14422
                     /locus_tag="IVD66_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145808.1"
                     /translation="MNLDKTNQTLREIMVCCQNIQQLIEYFGDNPTIFIQTNEYICAV
                     IGQCMFLRDLVRFSLPYQWKQDHQEVVWIRVVRICNMCAHPYKNRLNLFRLWFFIKCD
                     IPVLVAFCQKFLAQEK"
     gene            14612..15910
                     /locus_tag="IVD66_001586"
     CDS             14612..15910
                     /locus_tag="IVD66_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAP6145809.1"
                     /translation="MYLIPGISIVMYLLLVSGLILGLMRWSRLKEGYFASVYWRQLLA
                     RMLIDNRFVYTKKQVGEKQTKEKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGS
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     LLISGAIGGGKTYLLYSLIKACLDVGTVDICDGKAADLAALGDIDVFKGHVFYKTNEE
                     MIICLRNALQEMNQRYTYMKTMKEPKYEPGKNYAYYGIPPHFIFFDEWAAFYGSLDME
                     TRNKVDKLIQPLVLKGRQAGMYVILAMQRPDAEYFPSGVRDSLTFRISVGRLSPIGYL
                     MTFGDDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIEEFKKFDTMIVQD
                     FSVLKEEAFTSYEEQIDRQAQSLKGNTKTNGVDEESYTLL"
     gene            15932..16246
                     /locus_tag="IVD66_001587"
     CDS             15932..16246
                     /locus_tag="IVD66_001587"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145810.1"
                     /translation="MGEVLYRVSSAAGEISPDFAVRRLYEWINKVEYYTKGSYVFRRI
                     ERETLFVTRNQIVLTKEDILRFRQVYRLCKEKNIQLRLAILQCFAPEQYKELQEKEDS
                     LV"
     gene            16609..17865
                     /locus_tag="IVD66_001588"
     CDS             16609..17865
                     /locus_tag="IVD66_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP6145811.1"
                     /translation="MTPIELRNYRKKLSAIHASGGGKKLLSQKRFAQLLGCSVDYIKK
                     MEQGKKKIPEDFEKRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKIVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKQTVTQNVLVQFSGQGCREYEEVMREQRTD
                     WRTWLYSIWKNQGKLEAGYKRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKKFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISEIEAL
                     TKYGIYNRYELRLANEKATQAVEAFILDHSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDERWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIENAELNDEQQSYLEWMGTSGGKIA"
     gene            17862..18407
                     /locus_tag="IVD66_001589"
     CDS             17862..18407
                     /locus_tag="IVD66_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145812.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGTLKFIRFYRFSLPVPAILAVK
                     KGCDKMKIYENCVAALSNEKPLVEEISLATVTWEMNRQPTEEQTYLSLEEIELELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            18408..18908
                     /locus_tag="IVD66_001590"
     CDS             18408..18908
                     /locus_tag="IVD66_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145813.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPKEYPIEKRELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPINFLKKC
                     HLRILP"
     gene            18988..19545
                     /locus_tag="IVD66_001591"
     CDS             18988..19545
                     /locus_tag="IVD66_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145814.1"
                     /translation="MSLEFLGEPIEKEEFVSHYMDLFIRVIKKLCTIDEFYPREQDYL
                     AAERIKISLLWEKFTDENNRPPDYRYLSDCLTNNVLSKEYLFHKREKNQMSAEHFCDC
                     YIALLRSQQLLTVERYGAEFGYVMQAERHRATRCYEKEDQVIDGYEELCIRNNRYLQQ
                     RLYEKLMMDFSDLYRGYECSVIQER"
     gene            19565..19909
                     /locus_tag="IVD66_001592"
     CDS             19565..19909
                     /locus_tag="IVD66_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145815.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLGPRTERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            19928..20839
                     /locus_tag="IVD66_001593"
     CDS             19928..20839
                     /locus_tag="IVD66_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP6145816.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLSDVETELNGGTTEKPAEPEHLQPEKPEKEPVAPEPEIPESTLPTDPIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSETNTDSSSTEQPTMSFTSEEPKEEPKQPAEKSEAIPK
                     ENKPIVPAKEVTVSVTPNGEITTNNSQGMSVPIVTSNVEELTHIPTPTTPLKAEGGQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEVKTADGKTKVLPKTGEEIHVVLS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            20918..21910
                     /locus_tag="IVD66_001594"
     CDS             20918..21910
                     /locus_tag="IVD66_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP6145817.1"
                     /translation="MKKRQLRRKEKVYTEKVPNQRKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSQSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQEILKKEFYAQNFIQEPGSVSGIRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMDPENKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKTFIVKATVVFRDGDTSLLQKEQMTLVITKKTNQYYVEKLTHNWLDRKGDERK"
     gene            21907..22125
                     /locus_tag="IVD66_001595"
     CDS             21907..22125
                     /locus_tag="IVD66_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145818.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            22138..22548
                     /locus_tag="IVD66_001596"
     CDS             22138..22548
                     /locus_tag="IVD66_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145819.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFFIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYVV
                     RMMNGDCVYYNWDKVSNNALEELLFANKYVYLED"
     gene            22602..>24552
                     /locus_tag="IVD66_001597"
     CDS             22602..>24552
                     /locus_tag="IVD66_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAP6145820.1"
                     /translation="MVLVKEPVKALKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFYDVLNLIWLDVAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRMPKEHKGLLQLEDELGTSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEYKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATIIQQLHTTIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAIGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVEYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLD"
BASE COUNT         8355 a         3788 c         5171 g         7238 t
ORIGIN      
        1 aaaaaagggg tctgacacaa ctagtgtcag acctcctttt ttcaaataaa cagtgttcca
       61 gaagtagttt cttcgaaaaa taagccgaaa tttcttgaag ctgcccgctt ctgtcacaac
      121 ctcttttatt aggtattttt cactttttct aatttataac tttcaaagta acgctcatct
      181 tttttacttt gagaccatgc aaacaatccc attaaggcag cacctatcgt atttgtcagc
      241 aagtcgccca tcgtatccat caatgctgct cgtccgacaa acagtgtgcc atcagaagca
      301 gcaaaacgtt gaagattcat gcctaagaac tggtcgcata agaattccca gaactcccaa
      361 aacacgccgc aaagtccagc aaacgcaaag ccgaataaga ggaacaacca aggactggtt
      421 tttgatatct cagcatcttt catcaagtaa ccaatcaatc catagccaag agctgtcagg
      481 accattggac tcaccgcatg taagattttg tcccaaaaag agatgatact gatcaaatgc
      541 atccctgtgc ctaaaaagac agagatgaac aagaaaaacc agtaaaacaa aacgattgct
      601 gctggtattt taagtttgaa aactttcaaa atgacttgtg gcatgaaaat caatgcaatc
      661 cctaataaag attccacgat aaatgtgatt ccttgagaag tcgaatattt ttgtgtgata
      721 aattcataaa aattatagca gacaacgaat acaccaaaag caagtaaagc tatttgcacc
      781 tttttgattt ctttaatcac tgaaagtccc tccatctaaa aatcttttta cttctgaaag
      841 caactcaatt tctgaagaaa ccacttttcc gttcaatttg atcaaaccta ttgtatataa
      901 gttcaggtag tgaaattgat tttcagctgt ttcttgtagt gcagcgattt ttttcgggtg
      961 ggttccgcct tgctgtcgag tatcagtata taagccgatc actgggatgc ctttcgcata
     1021 agccacaccg atttccgatg ctaccccggc atcgatcgtc agcccatcta gtaaagcaat
     1081 cattaaatca ctagccaaca ctttttctgt gtcagcaaga gcaatcattc gactgtctgc
     1141 ataagcagtt ttgtcattga ttgcttcatt ttcttgagga agatagatcg aaagctcaga
     1201 agagagctct ctgatttctt taactaactg ttggttatat aacaaatcac ttttagcaaa
     1261 cattggtgcg gcaaaataaa ttttcatcta aacatcatcc tttttatcaa aaataatcgc
     1321 taaagtaagc ttccatgttt ggaatgatac gctctagtga cttcagtgtt tcttcatctg
     1381 tttctaaccg ttcgattctt gccaaataag aagcacggcg ataattcatc atcaagcaag
     1441 tcaatgtttg gatatccagt cgaacggatt ttcctatagg ttcatttaag acacggactt
     1501 gtccctgttc atcccatgtt aaagcgaaga caccattatt ccaaggagcg acaggatctt
     1561 caatgatgaa atgaaaagca tcagctgttc caacaaacgg aaaccgttga aggaattctt
     1621 ttacatcaac gatccgagcc ataaaatatg gttcgatctg ctctttgatc tgactatctt
     1681 caatcaaaaa tgctaaaggc tcatttttat aaatatctcc atgtacccag tagatcatgg
     1741 aaaaatgtgc ggaaataaag ttccataagc catttcgagc ttcttgatca agatagaaca
     1801 tttcttttac gtgaaatatt tcttcagcta cccagtagaa cagaacacct cttggttcat
     1861 ggttgctatc gtagtagaca gcggctgtgc gctcatcttc attttcgaaa cgccaatact
     1921 cttcccaatg aaaatcactg cggaataaag caccatggtt ttgttgggca aatttgtcat
     1981 aaacggaaaa tacgtctgga tgatcaactg gtaatcgctc aaccatacca cttactggga
     2041 tttgtttagg tagctgtgta tctctgattt taaaggaaag tttatcagac atgatttccc
     2101 atcctttacg ccgatagtag gggatactgt aaggatacaa ataagagatc cattgcttat
     2161 tcttgcgcat attatccaat gcaacgataa ttagatcttg catcaatcca tggttagcat
     2221 attctggata agttccaact ccagtcacac cacccatttt ataacgtgca ccgtgaatat
     2281 tgacttcaca aggatagata gcgatttgag agatcagttt attttcgtgg aaccatccga
     2341 acactttcga tacttccaaa atcggttttt tggaacggat aaaagctcgt ttattctcaa
     2401 acccgctttc ctcgatgtct gcttcagtca cttggaacac ataggaaagc aattcattga
     2461 attgatcgat atgttcttga gtgaccggtt ttaattcaag attttctcta aaatcttttt
     2521 gatccatttt ttcatctcca tttattagct tgataacagt atagcaaaat tctacaaaaa
     2581 aaacttctat agctgactaa ttaaaaactc tttaaattac tgcttttcgt tggtataatg
     2641 gaaagtgctg attatatgaa aagaggagac gctatggata taaagaaaat gaaagaacgc
     2701 caagagcaga ttcgtaattt ttcgatcatc gctcatatcg accatgggaa atctacattg
     2761 gccgatcgta ttttagaaat gacgcacact gtgacgtctc gcgaaatgca agatcagctg
     2821 ttagactcga tggatttgga acgtgaacgt ggaatcacga ttaaattaaa tgctgtagaa
     2881 ctcaattaca cagcgaaaaa tggagaaaca tatatctttc acttgattga caccccaggg
     2941 cacgtcgact tcacctatga agtctctcga agccttgctg cctgtgaggg tgccgtttta
     3001 gtggtcgatg cagcacaagg aatcgaagca caaacattgg ccaatgttta tttagcgtta
     3061 gacaatgatt tggagatcct gccagtcatc aataaaatcg acctacccgc agcagatccc
     3121 gaacgtgtcc gtcaagaaat cgaagacgta atcggaatcg atgctagtga agctgtatta
     3181 gccagtgcca aatcagggat tgggattgaa gatattctcg agcagatcgt ggaatatgtt
     3241 cctgcaccaa gtggagactt agatgcaccg ctaaaagctt tgatctttga ctctatttat
     3301 gatagttacc gcggtgttgt tctaaatgtc cggatcacgg acggtatggt caaacccgga
     3361 gacaaaatca aactgatgag taatggcaaa acatttgatg ttacagaggt cggggtcttc
     3421 tcgccaaaag cagttgctag agactttttg atggtcggtg atgtcggtta tatcacagca
     3481 agtatcaaaa ctgtccaaga tacacgagta ggggatacag taacgttagc agacaatcct
     3541 gccgctgaag ctttaccagg ttaccgaaaa atgaatccga tggtttattg tggtctttat
     3601 ccaattgata cttctcgtta caacgatttg cgggaagctt tagaaaaact gcaattgaat
     3661 gatgctgctt tacaattcga accagaaacc tctcaagcat taggttttgg gttccgctgt
     3721 ggattcctcg gacttcttca tatggatgtc gtccaagaac gcttggaacg ggaattcaat
     3781 ctagaattga tcacgactgc accatccgtt atttaccatg ttaataaaac ggatggtacg
     3841 actgctacag tagataaccc ggcagatttt cctgaacctg taacgattca ggatgtagaa
     3901 gaaccattcg tcaaagcaca gatcatggtc ccaaatgatt ttgtcggtgc agtaatggaa
     3961 ctttctcaac gaaaacgggg agaattcatt acgatggatt atttagatga ttaccgagta
     4021 aatgtcgtct ataatattcc gctttctgaa attgtctttg actttttcga caaattgaaa
     4081 tcaagcacga aaggctatgc ctcattggat tatgaaatgt ctggttatca aaaaagcaag
     4141 ttagtgaaga tggacatctt gctgaatgga gaaaaagtcg atgcattaag ctttatcgtt
     4201 caccgagact ttgcctatga acgtggaaaa gcaatcgttg aaaaactgaa aaaactaatc
     4261 ccacgccaac aatttgaggt gccaatccaa gcagctattg gacaaaaaat cgttgcccgt
     4321 tcagacatca aagccttgcg taaaaacgtc ttggctaaat gttatggtgg agatgtttct
     4381 cgtaaacgta aactcttaga gaaacaaaaa gaagggaaga agcggatgaa acaaatcggc
     4441 tccgtcgaag ttccgcaaga agccttcatg gccgttctga aaatggatga gcaagatagt
     4501 gtgaaataac ttataatcaa tcgaaaaacc tattaaatca acctttttga gtagatgcaa
     4561 cactgaggat tatctgtata aaagatttta aactgtcatt tggttatcac ggcgatacta
     4621 aaattaacaa aattggaata ttttttcttg aagattttta gctgtcagta tatgatgaaa
     4681 gcatctcata ggaggtgctt ttttcatggt tgataattca agtggaaggg ttcttaaatc
     4741 tctaagaaaa gagaaaaaac tatctcaaaa aaagttagct gatttagcag gtatttcaca
     4801 aagtacttta gttaaatatg aaaaagggtc aagaaaaatc cctaaagacg tagataatac
     4861 tctaagcaag attttgaata tagaaactct aataaaagat gaggaagata agattgagat
     4921 tctcatcggt caactaattg catacagaga tatgaataag ttacttaaca aagagttagc
     4981 tgataatata ggaattagtg aagtattact cagttatgtg ttaaatagaa agagaaatcc
     5041 gtcaaaagaa atgcaaaaaa aaatcgatat ttttctatta agtaatgaaa aagaaatttc
     5101 gaaggagagt aatcgtgata gtgagatatt tagtttatca aaagacgata aaattgttat
     5161 gggaaaaaga atacgagaag tccgaaagaa ccgggaagag acgcttgaaa aatttggtaa
     5221 aaactttacc atctatacag gcaaaaatgt tataagtaga tgggaaaaag gtattaatat
     5281 tccagatatt gaaaaactaa tgaatattgc ctatcttggt aaggtcactg ttccttacct
     5341 tatgtacgga gaagattata agaatatact tccaaaagat gaaagagtta gcgattttaa
     5401 caagataaat tcttttagta tgggattaag gatgaggaaa attaggaaag attattatct
     5461 agaaagggag gagtttggaa agcttttttc tccttcaatt tcaaaatggt ccatagatag
     5521 gtatgagaat ggtagagata tacccaatac taatcgaatt atccaatatg cttatatagg
     5581 aaatctttct ttagaatttt tgatttacgg gatataaaaa tagtttacgt cgatacttat
     5641 taagttatcg acgttttttt attatagaaa aatttataaa aggaggtttc ttgatatgat
     5701 aagaaacaaa aagggtttgt tgaaagttgc tttactggca gcttttttct aagtaacttt
     5761 ttgacaagct caatggcaac acaagcggaa gaagtaatac aagaaataac tgttatgaat
     5821 accagctaga taaaatgggc taggtatgtt atccaacaat ttagtaatca ctagaagcct
     5881 agcgaaagtt cgcttgataa gttatagatg agtattgatt tgtagtcttt ccaaatcaaa
     5941 agggtacaga gccacatgaa atatgttgtc ctctgcagcg tcaggatggg aatccatacc
     6001 atggaaattc ggagatctgt gagggaatac ttacgtggtt aatatgtcgg ttgtgttgga
     6061 cgtagtaatg gtcatagtgg gtagattgac tgaattctta tatgagaaaa tgaaaccaac
     6121 aagaagatag ggttatttat acagaattgg ggatcttttc tagaaaagta atcggacaat
     6181 gcgagattcg tacggtcttt tttaaatttc tcttaaaaaa acggcatcga atgggttggg
     6241 tgattgataa gcaatgaatc atagactgat atagaataaa aaaatgattc tatttatctt
     6301 tttacatcta tcgttttttc aagtaaccgc aaattgtatc agcattcaac aatttttgta
     6361 tacaagttct agtaaaagga tctgaagaaa aagttggttg ttgtgaagat aaaaaaagaa
     6421 tcaggtttta ctgagttttt cttcaaaatt tgtgttatta ggttaggaca aagataagaa
     6481 gaagtatgaa gatttaaaaa aggaatgagg aaaagatagt aatttccgat tattggagtt
     6541 tttttatttt ataaagaaga agcgaacaag ttgtgattcc tagatttcgc gcgtgattaa
     6601 ttaatgagca aaaaatgcgg aaagttttag tgtttaatac acgaggacaa agtttcttag
     6661 gtattgaagg cacacgtgta acggttgatg ggtggtgtga ttgtttcgag gttggaaaac
     6721 atgttgaact tatggcattt actgagctaa aagataagaa caacgtggaa tttgtcgaga
     6781 gtgatattgg ttgggacgat catgaagaag tttatggaaa atttattttg cggaagggaa
     6841 attcttatac gaatggggaa gcataagtag cgatttgtta gagatcattg ataggattga
     6901 aattgtcggg aatatttatg agaatctaga gttatttgag gtgatagaat gagtgatggt
     6961 tttgaacaag tatcaataat taaaaatcaa gttcgggaga ttcttagaaa aaaaggctat
     7021 ttggtagata gttattttga aggagattac gaaacatggg taggtgtcta tgctcgtcca
     7081 gagaataaac ctacctattt agatcctacg acgtcagaag atgcctattt acaaaatagg
     7141 tatcgagtag atggttttaa gcaagacttt gcggagtggt ttgaatggga aattgaaaac
     7201 ggagaagtaa aagaagaata agcgtacttg ttgtatcaaa ataagtcagt agaacaacca
     7261 aaccagtagc tagtaatgac aataatactg gggaatcgga tcattatggt gtgattgata
     7321 tttctattcc agaagatctt aagccagatc ctgcaacaat tggcaacagt ggcatgattt
     7381 ttgattcgtt agatgaagct atgtcatatg gttggaaaga aattaaggat gaaggtagta
     7441 attggtatgg catgatattt ggtgatggtg aagttgccaa taaagctggt attccaattg
     7501 ggaaatggac agttgatttc cacgaagcag gttctttttt tgttctgtaa ttatagtggg
     7561 agggtaaaat cattgatgaa atgtgttcag ataagagcgc cagataaaaa tagaagagac
     7621 agttcacgtc gttatcactt ttggtaacgg tgttttgttt tattatataa aattctcagg
     7681 aaaaggagga attcttgtgt atgcaaaaac gaaaatgaat tggttgaaag cactcgcatt
     7741 ggtggcctta tctcaattct gtttcttggt gggaactgct caagcacatg cagaagaaac
     7801 gacggctaca caacctacgg tggaagccat tgcccaagtc gcttctgaag tgacagaagt
     7861 ccaaccagca gaagccgggg tcccagctgg tgaagccact gttgaacagg cccctgtgac
     7921 agaagcgcca acggttaatt ccaaaacgac tctcgatcag acgattgggg aaacacaaca
     7981 cccagggaat agtcctgtta cttcacaacc agttgaagaa actgcctcaa ttacaacccc
     8041 tgcttcagaa acgtccactc cagaaggaga aaaagctgcc gaagcaacgc cttctgtgaa
     8101 gccagagtct tctgagaaac aagcggaaga aaagcaacga atagaagaaa cagtggaaca
     8161 accagcggct actgctgaca aagaaggaaa aaatgaggaa aacgttgaaa aaacaatctc
     8221 ttcaaccgca gctagtcaaa atcaaccaac gaaactaaac aaagaatcta cggctagtat
     8281 tgaagatcaa aagaaaaaag agcaggacat tccaaaaaca ggtacaccta cactgttagt
     8341 aacagtacca accaatcgtt cggttcgtgt tcgccgtgca accaatacag ctgttttagg
     8401 tggtcggaaa attgattggg gcgaaaatat tggtgttact tctagtccga acaatccaaa
     8461 cttcacttta aattatatgg ttcgttttga gattaatgga caagtggcgt tttgtattga
     8521 gcctggtgtc tcagccgcag aaggtcaagt ttatacagct actgctttgg aaaactattt
     8581 gaaaaattca aatgtacgga aaaaaacaag cttgatctct tatttaggat atgtcacaaa
     8641 taaagacaaa tccgatgaac aatacattgc ggcacaattt atgatttggg aagctttggg
     8701 cacaaaaatc ccaatcaaaa atatccgtgt tgattatgat cgtcgaaaag cagaaattca
     8761 acgtctgctt aataattttg atgtaagagc tacttttcat aatcaaacac atacgataaa
     8821 aattggcgaa acgttaaaag taaaaagtgg caatgacttt ctacaacgtg taaaaggcat
     8881 tcaaaagcca aaagggatca atgtatctat tcatgggaat gaagcatgga tcacagtcac
     8941 aaaagaagca ccagaaaagg caaaaattca tttcaatcag attgaagtat tgggtacgcc
     9001 attagcgtat cgtcgtccag gtgcccaaac aattggtata ttgaatcctt ttgaacctgg
     9061 tgactctgtt gtcaatttga ctattttgaa acagggaaac attcgtgtct ttaaagaaga
     9121 tgcagaaacc ggtgtgaaag cacaaggcgc agcttcttta gaaaatgcgg tgtatggctt
     9181 gtatcaagca gatgggaaaa agatcaaaga aattaccttg aaaaatatga acggcaaagt
     9241 acaggcagaa attaaagatc ttgatcctgg caaatatgtt ttaaaagaaa tcaaagcgcc
     9301 gaaaggctat gcactttctg atgaaacaat tgaaattgtt gttgaaccag gaaaaactgt
     9361 caatgcgacc gcaaaagatc aagtgatcaa aggaaccatt gatttagtga aaattgctaa
     9421 taaagattta gtcgattcaa ccaatccaga taacaaacca aaattagctg gcattgaaat
     9481 ctctttgacg tcaaaaacaa ctggcaaagt ggtgaaaacc gttgtgacag acaatgatgg
     9541 ttacgctact tttggtaaaa atactgttgt ctttgatacc tacattcttt ctgaaaccaa
     9601 aggaaaagaa gggtataaac tatttgaacc acttgaagtc acaatttctg aaaatgggca
     9661 aactttccat tatgttttag aagataaagt aattgaacaa cgtcttaaag tggtgaaagt
     9721 ggatcaagaa acaggaaaag tgattccact tgccaataca gaattcaaga tttttgatac
     9781 tttagccaat cgttatgtca caatggagat tccaaatgat acagaaacaa cggatatctt
     9841 taaaaccaat gaaaaaggct ttttcctaac taacggtaca cttacttatg gaaaagagcg
     9901 ctatcgtttg gaagaaatca aagcacccgt aaattacgtt ttgaatcaaa acccattagt
     9961 gttctcgatt accaatgata cagaaccgat caaagtgatc cattttgcga accgtcaagc
    10021 acggaaaagt gtaaaattgt tcaagtatga agaatggaac aagaagaaaa caccacttgc
    10081 cggtgtgacg tttacgctat ataacggaaa aggtcaagca attggtaaat ataccaccga
    10141 tcaaaatggt gagattttag taaaaggtct ggttgccaat aactattact ttaccgaaaa
    10201 tgtaccatta gaaagtttcc aaccaaatac aggcaaacaa gcattcacta ttacattcag
    10261 acaaaatgcg ccagatgatg gggaaacgtt attggtttct gtacgtaact atttgattcc
    10321 accaaaatta gaaacacaag cgtcaaataa agccgatggt gaaaaagtgg ttgatccatt
    10381 agaaactatc gtcattaaag atagtgtttc ttataccaac ctgtttgtcg gcaaagaata
    10441 cactatttca ggtgtattga tgaacaaggc aacgaatgcg ccaattttac aagaaggcaa
    10501 agaaatcaca agtatcttga cctttattgc agacaaagcc aatggcacaa aagatcttga
    10561 atttgtggtt aatgctagtg ttctgaaagg tcaaacaatc gttgtctttg aaaaactttt
    10621 ccgtgatggc attgaagttg cggtacatgt ggatatcaat gatgacaatc aaagtgttcg
    10681 ggtaaacaat ccaacggttc ataccacagc tgtatttgaa gacgggttga cgatcgcaga
    10741 cccaacgggg ctgttcacct taaatgatac cgttgaaatt aatgagatcc ttccaggaaa
    10801 agcttacttg gtcaaaggaa tcttaatgga taaagcaact ggtgaagcct tacttgttca
    10861 tggtcaaccg gtagaaagtg ctgttggctt tattgccaaa gcagaaaatg aaacggtgat
    10921 cgtaccattt acctttgatt tgacaggttt aaatggtcgt gaaatggtcg tgtttgaaag
    10981 tctttttaga aatgacgaag aactagcaaa ccataaagac atcaacgaca aaggtcaaac
    11041 ggtacgagta acgaacccaa gtgtacgtac aacggctaca cataaaccca ctggcttgaa
    11101 agaggttaat ccattaacga aagtcaccat tacagacgct gtgaaatacc acgatttgat
    11161 cgttggaaaa acatacacag tcaacggtgt tctaatggac aaagtaacgg aaaaaccagt
    11221 gctagtagat ggaaaagaag tctcaagtac cttaacgttt gtggcagaaa caactgatgg
    11281 tacagtcaat ctagacttta tcctagacgc acatgcgttg cgaagcaaag aagtcgtagt
    11341 ttttgaagat ctgtttagag aaggcgtatt attggcttct cacgcagata ttaccgacaa
    11401 agaccaaacc atcaaaatcg tcagtccaac cattacgaca aaagctacca atgcaaatgg
    11461 tggaaaagag atcttagctt taccaaatca aaaggttgtc gaatgggttc aagttaatgg
    11521 gttagcaatc ggtcaaattt acaaactgat tgttcaaggc tacttaacac cagacggcac
    11581 cccatttgaa ggaacacatg cggaaaaagt ctttatggct gataaagaaa tgatggaatt
    11641 cttgtttgaa ttcatcgttg acggtcgcaa ccttgcagga aaaggattga gttttgcgga
    11701 atggctccaa gccaaaacag aagatgaaaa agaaacgttt gaagaagtcg caaaacataa
    11761 cgtcgatcta acaaacaaag atcaaacggt tcaatttgtg gaggcaccaa aaccaccgca
    11821 accagtaaaa ccaaacgaac cacaacctgt aaaagaagtg aaacaagctg caatggtacc
    11881 tatgttgcca aaaacaggct ctgaagacaa tgtattatgg atcatgattg gtatgatctt
    11941 tgtccttgcg gcaggattga ttggttatga tttgtataaa gtcagagact aaagaggacg
    12001 aacaagcggt taggcaacta gccgcttgtt tagtttttag aaagaatttt ttatcaaagg
    12061 caaataaatt attgtgttga gtagtaaatg atcatgagga tacaccaaga aatactgagt
    12121 gtaataaata agaatttaag gatccaaaag agatagaata taattatgtg ataatacagt
    12181 ttcttttttt ctatagaaga aatcacgttt agctactcct aattgctttc ttactttatt
    12241 tagttctgct aggtagcagt atgagaattc aaaatacatt ctttgtactt tgaagaggat
    12301 ttttttcgaa tgtttatttg tgttaattat tttttgtatt tctttggcaa aataaataag
    12361 ttcataaggc aaataaaagt ctatattttt attttcaact gtttggatta gatgttgaat
    12421 tgtttgtttt cgttctagaa tattttttct tgtaattttt tgaaatagat aattttcaat
    12481 tgaagattta aatggaataa acatttcttt tgttagggtt tcagtgcttt tcttttttct
    12541 tgtatagcga tgttttaaat aaaagctaga aatggaccaa acaatagtga cgattgaaac
    12601 tatacttgag atgataatgt gtaattcatt tgaaaatagt tgttgaataa aagtgtttat
    12661 aaaaataatc tcctttttta taaaaagtta gaaaggatgt aaaagagttg gaagaaatat
    12721 tcttttgtat gatggtagag tttttgtttg tatcaattgg tttcttaatt atgggggagg
    12781 caattatgat atatcttttt ccgtttgaca gcaaggatga gtgcatcttt agtagtatta
    12841 ttattttctt tattttagca tgtgtgtgga ttcttgctag ggaaatatat catcagtttg
    12901 tgttggaaga tggaaaagga attattactt ggtttttaca gaaaagaaaa taatggagga
    12961 aaaaagaata tggaaaagaa aaatataaat atttgttttt tgagtggaaa agaatgtacg
    13021 tatgaggagt gtactgatat ttctgtgcat gaacgagacg ggatgttaat agtagatatg
    13081 tctcctagtg atgagccatt tgttgttaaa cattactttc cattgtgtaa tatagagtcg
    13141 tttagaattg attgtgaatt ttaagaggag gaaaaatgat atggcagaaa aagcattgcg
    13201 tatgaagaaa gagtttttag gtcaggtatt tttattgggt tcacgggaac ctaatccacc
    13261 aaaggaaatt aatggtgtgt ctgggcgata tgttcaatta caagcagaat gttcgcgaga
    13321 agaacagcct gctttttttg tttatctcac agctgaagag gataaaagat tacgattacc
    13381 agaaaaagag gtacgtattt catttgaaga agcttatttt gtttttcgta aagaaagagt
    13441 gaatagtcgt gaaacaaatg atatgggaca aacagagcgt cgaacaactg gctatcaaga
    13501 tgtcggtgtc tttttaactg gtgtaaaaat tgaggaggtt ttgtaagatg ggattaaaat
    13561 ttccaaataa ttatgatatt acagaagcat tagatgaaac ttgtatagga gccgtacgct
    13621 ttggcgcatt agaagagtcc gatcgtgtat ttgataatga aacaggcgat tatacgggag
    13681 aaattcgatc acagcgagca caattagttt ttggaaatcc agatgaacca aagattgcac
    13741 gacgagttaa atttccagca gatgtagatt tgactggttt taaacgacgt gatcctgtga
    13801 aattaattga tccagaatat catgtggtat atattccagc acaagatggc aatcgtgaat
    13861 attcagattt agtgatttat gcgaaaggat tagagaaagt agaagctcca acaaataatt
    13921 ctaatccgaa acaatcacaa gaaaaaggtt tagatcaaaa acaaccaagt gctgattcta
    13981 aggaaaaaga gaaaaaataa gttttttaaa gagtaggagg aagtcttcct actctttcta
    14041 tttaaggtag aaggaagggg agattttgaa tctggacaaa accaatcaaa cacttcgaga
    14101 gattatggtt tgttgtcaaa atatccaaca attgattgag tattttggag acaatccaac
    14161 gatttttata caaacaaatg agtatatttg tgcggttatt gggcagtgta tgtttttacg
    14221 tgatcttgtt cgtttttcat taccgtatca gtggaaacaa gaccatcagg aagtggtttg
    14281 gattcgtgta gtacgaatat gtaatatgtg tgcacaccca tataaaaatc gattaaatct
    14341 ttttcgatta tggtttttta ttaaatgtga tattccagta ttagttgctt tttgtcaaaa
    14401 atttttagca caggagaagt aaaaacagaa aggaggaatg tgacaattgg aacctcattt
    14461 ttttaagtat cgtggtcgac gaattcgtta tttcaatcgt tatttatggt tttgttatta
    14521 tggtttcttt ctgttaccat ttttgattct attaagttgg tttagttgga aagtatttta
    14581 tcctcgttta aatacgtatt cgaattggca aatgtatctt attcctggaa tcagtattgt
    14641 gatgtatttg ttgctggtta gtggattaat tttaggtttg atgcgttggt cgcgactaaa
    14701 ggaaggatat tttgcttctg tttattggcg tcagttactt gctcgaatgt taattgacaa
    14761 tcggtttgtt tatacaaaga agcaagttgg tgagaaacaa acgaaggaaa aaatgagatt
    14821 accaaaagtt tatttttatc aaaagaaaca agaattagtg gtttcttttc ctttagatgg
    14881 tggccgtttc cacgaacgat ttttaaaaat gggtagctta ttatccgaag tatttttgcg
    14941 tgatttaatt cgtgaagaac gagaaaaagc ccgaatcaat tatgtatttc tttccgattc
    15001 tggtcggatt cctattgatc aatgtatagc agaaaatgga cgtattcatt taatgaaaac
    15061 attggattgg gtatatgatc aatcgccaaa tctattaatt tctggtgcga ttggtggcgg
    15121 aaaaacctat ttattgtatt cattgatcaa agcttgttta gatgtaggga cagtagatat
    15181 ttgcgatggg aaagcggcag atttagcggc attaggtgat attgatgtat tcaaaggaca
    15241 tgtgttttac aaaacgaatg aagaaatgat tatttgctta cgaaatgcgt tacaagaaat
    15301 gaatcagcga tatacctata tgaaaacgat gaaagagcct aagtatgaac cagggaaaaa
    15361 ttatgcttat tatgggatac cgccgcattt tatctttttt gatgaatggg cagctttcta
    15421 tggttcgttg gatatggaaa cgagaaacaa agttgataaa ttaattcagc cattagtatt
    15481 aaaaggtcgt caagcaggca tgtatgttat tttagcgatg cagcgaccag atgcggaata
    15541 ttttccaagt ggtgttcgag atagtttaac gttccgtatt tctgttggcc gtttatctcc
    15601 cattggctat ttaatgactt ttggagatga ttttaagaat aagccgtttt ataacaaaga
    15661 tcaacctggt cgtgggtatg cttttcctgg ttttgatgtg cctgtagaat tctttgcgcc
    15721 atttgtttac aaagactatc actttattga ggaatttaaa aaatttgaca caatgattgt
    15781 gcaagatttt tctgtactga aagaagaggc gtttactagt tacgaagaac aaattgatcg
    15841 tcaagcgcaa tcgttaaaag gaaatacgaa aacaaatggg gtagatgagg aaagttatac
    15901 acttttataa tttagaagga agtggtgaag tatgggtgaa gttttgtatc gtgtttcttc
    15961 agctgcgggt gaaatttcac ctgattttgc ggttcgaaga ttatacgagt ggattaacaa
    16021 agtagaatac tacacaaaag gttcttatgt tttccgacga attgagcgcg agacattgtt
    16081 tgttacgaga aatcagattg ttttgacaaa agaggatata ttgcgttttc gtcaggtata
    16141 tcggttatgc aaagagaaaa acatacagtt acgtttagcg attttacagt gttttgctcc
    16201 tgaacagtat aaagaattac aagaaaaaga agattcattg gtttagatat cggggtggct
    16261 ttcataggga ctatgggaga acacattgtc cgagtatgtg ctgccgcggc ttgtgtcggc
    16321 gaagccaccg agaccagtcg tggcagcaca tgcttggcat gtgtgcccac aaagaggtcg
    16381 tgcgcttgcg cacggcctct ttgtgtaaag ccccccgata tataatatgg ggggcagaaa
    16441 taacataaca caaataaaaa agtgtattta aatcagttat atcaaggctt tagctaaggt
    16501 tagaaggagt actccttttt agaaaaatta gggggtacca cctgttatat cgggatttct
    16561 agcagattaa gaaaatcgaa atttgttatt ttataaagga ggtagaatat gacacctatt
    16621 gaattgcgaa attatcgaaa aaaattgagt gctattcacg cttcaggtgg agggaaaaaa
    16681 ttactctctc aaaaacgttt tgcacagtta ttgggatgct cggtagatta tataaagaag
    16741 atggaacaag gaaaaaagaa aatcccagag gatttcgaaa aacgaatcaa ggaacgcttt
    16801 cgattgtata tgaaaagcgg aatagatctt cgagcaatga tcgactattt gcgtctctcc
    16861 ttttttggga cagactacaa aatagtgatt caacgtgtgt tacgaatgga tctaacagaa
    16921 tttgaaacac gtccgacggg cttgtatctt tttgattgtc tttctgttcg tggaaatatc
    16981 tgggtattct ggcattcaaa acaaactgta acacaaaatg tacttgtaca gttttcgggt
    17041 caaggttgcc gagaatatga ggaagtcatg cgtgaacaac gaacagattg gcgaacatgg
    17101 ctatattcca tttggaaaaa tcaaggaaag ttggaagctg gttataaacg agtacaatgt
    17161 agtcgattcg atattgcgtt agatgaactt tggggattgg aaacagaaga acattttgat
    17221 ctctttgaat tactagaaaa acaaaaagca ggtttattag aaatggactt taagaaattt
    17281 cagaatattg gcggttgttt tttagatgat ggttatttcc gaagcgaagg gttatccttg
    17341 tattttggat cgcgaaagag tccattgttt ttcaatttct acgaaaaacg ttttgaaatt
    17401 gcgaatcgtg agaaaatttc agaaatagaa gcattaacga aatatggcat ttataatcga
    17461 tatgagttac gcctagctaa tgaaaaagca acacaagcag tagaagcgtt tattttggat
    17521 cattccccta aacgtttagg agagattggc gttggtttaa ttaatgcaaa acttattgtt
    17581 tgggatcgac tggaaagtga tgcacgaatt gttgatgaac gatgggcaaa attgtttcgt
    17641 tcgatggaag aattggattt taccgtaaag ccagaaaaat tctcattaga tcgttcagaa
    17701 cgctggtttt tgaaacaagt agctccgaca ttaaagttat tacaagaagc agatcgtatt
    17761 ttaggaagag actttgtaca agaaggaatt gagaatgctg aactaaatga cgagcaacaa
    17821 agctatctag aatggatggg aacgtcagga gggaaaattg catgaatgca tatacgacaa
    17881 cagaatggct gcgtcttttg gatttaaagg ctgcaattga agcattaaat gaaaagatgg
    17941 ttgatttgtc ttattttcgt tttcgagttc cttatattga acaagcggta aaggctggac
    18001 gttatcagga aaaagaaaac tggcaagaaa ttgcacgctt attagaagtt cgtaaggggt
    18061 acgaacaaga actcgaagag ttggaattta gccgaagaaa aggaacgcta aaattcattc
    18121 gcttttatcg attttcattg ccggtacctg cgattttagc ggtaaaaaaa ggctgcgata
    18181 aaatgaagat atacgaaaac tgtgtggcag cacttagcaa cgaaaaacct cttgtggaag
    18241 aaatctcgtt ggcaactgtt acttgggaaa tgaatcgcca gccaacagaa gaacagacgt
    18301 atctttcttt agaagagatt gagctggaat tagaggaaat cggccgctat gccacttgtt
    18361 ctacctattg tggatcggtg attagtattg ctggtgtgat tgtctaaatg aaaaaaatta
    18421 tgatttatgt tggtgcgtat tggtcgcgtg atccaacagt attagaaaat ccagaagcag
    18481 tacactattg cttgcgccaa ttattctatc tgtataaaga acgattggaa tcattgattc
    18541 gtcagttgcc atatactgac agacgtttgg atgaacttct tctaaggtat ccagcaatgt
    18601 ataaacgacg aaaaaataga ttgttaccaa aagagtatcc cattgaaaaa cgtgaacttg
    18661 aagggcgatt tgtggcttat ttctatgatg atgttcgtat gcgcttagta gaacaacgaa
    18721 tggaaataga aaatgatcgc tactatttta tcaattattg taagaagcgt aagtatcaag
    18781 taactgatga tttttatgat tgtattttac aagatgggga agtgattcta tctaaaattg
    18841 ctccaagttt tcgtgaactt gtgccgatta attttttgaa aaaatgtcat ttgcggattc
    18901 ttccgtaaaa aagagctata aaaggaaaga aaagtagaag ccaaatcggt ttctgctttt
    18961 ttatttttta aggaaggaga agatggtatg tcactggaat ttttaggaga gccaattgaa
    19021 aaggaagagt tcgtttcgca ttatatggat ttgtttattc gggtgataaa aaagctttgt
    19081 acgattgatg aattttatcc acgcgaacaa gactatctag ccgctgaacg aataaaaatc
    19141 agtttattat gggaaaaatt cacagatgaa aataaccgac cgccagatta tcgctattta
    19201 tcagattgtt taacgaataa tgtgctttct aaagaatacc tatttcacaa acgtgagaaa
    19261 aatcaaatgt cggctgaaca tttttgtgat tgttatattg cattattgcg tagtcaacag
    19321 ttattaacgg tagaacgata tggtgcagag tttggttatg tcatgcaagc tgagcgtcat
    19381 agagctacaa gatgctatga gaaagaagat caagtgattg atggctatga agaattatgt
    19441 attcgaaaca atcgctattt gcaacaacgt ttatacgaaa aattaatgat ggatttttcg
    19501 gatctctacc gagggtatga atgttcggtg attcaagaaa ggtagaagaa aagggggaat
    19561 ttttatgtgg cgattattat ttttggtggt atgtggtatg gcattgttct atgtgtatcg
    19621 tgtctatctc ggtccacgaa cggaacgatg gacaagttgg tatagagatc ctttaaaaca
    19681 acgaaaagga ttgaagcggt atcgttatga attacttgtt gaattttcgg atgggcgaca
    19741 agcacagtat tatttttttg caaactatcc aaaatacaac accagtgaac tattgattca
    19801 attattcaaa aataatccat atgttgggtt agaagaaaac ggacgggagt tcttttatcg
    19861 ttcagataat attagtgcgg cgtctatgaa caaaacacga attgcataaa aaattggagg
    19921 aataatcatg aaaaaaacaa cattagcagt cgtaacaaca ctaggaattt cattattttc
    19981 gtttcaatta gggagttcat tggtttatgc agatgaaact gtagaaacac ctaagtcaga
    20041 aattgtagaa acattgccag gggaaggatt atcagatgtt gagacagagc taaatggagg
    20101 aacaacggaa aaaccagcag aacctgaaca tttgcagcca gagaaacctg aaaaagagcc
    20161 agtggcacca gaaccagaga ttcctgaatc aactttgccg actgatccaa ttgaagaaga
    20221 aggtgtgcac agttcaacaa caacggattc aagtatagtc acaactccag aacaatcagg
    20281 aacaaccagt tcttctgaaa cgaataccga ttcgtcaagt acggaacagc caacgatgtc
    20341 gtttaccagt gaagaaccaa aagaagaacc gaaacaacct gctgaaaaat cagaagcaat
    20401 tccaaaagaa aataaaccta ttgttccagc aaaagaagtc acagtatcgg taaccccaaa
    20461 cggtgaaatt acgacgaata attctcaagg aatgagtgta ccgattgtca ctagtaatgt
    20521 agaggaattg acccatattc caacaccaac aactccacta aaagcagaag gtggacaaac
    20581 aattgttggt gtaaaagatg gaattccatt aatccaagat agtgaaggga atttggtaaa
    20641 ggatttgtcg attcctgtaa agaaacttcc aagtggcaat attgaagtca aaacagcaga
    20701 tggaaaaaca aaagtcttac caaagactgg tgaagaaata catgttgtac tttctgttct
    20761 aggaggagtg ttgacaagta ttgctggatt tgttggatat aaaagaaaga gaaaaggaat
    20821 agaaaatgag ggtaattgaa tggactattt ttcagaaaaa caagcttatc gttgtcaatc
    20881 gtacgtacta gtaaaaacat actagaagga gtagcttatg aaaaaacgac aactacggcg
    20941 gaaagaaaaa gtttatacag agaaagtacc gaatcaaagg aaaatccatt caaaaaaagc
    21001 agtgaaatgg atttggtgtt tggttttatt tctttgtttt tcagggggct tggcattttt
    21061 tcaatccatg aaaacgaagg ttcaagtgtc gtttttgaaa gatgaaatcc aacaattaca
    21121 aaagaaagaa gtacaaagtc agtcagaatt aacgtacaca cctgaaattg aatcctttat
    21181 gaatcgtttt gttgctttgt atatgaatac attcgataat catgaacaag aacaacaacg
    21241 tcaagaaata ttaaaaaaag agttttatgc acaaaacttt attcaagaac caggaagtgt
    21301 ttcaggtatt cgaaaattaa ctgctgcttc gtttattgga ttaaaagaaa ttgaaaccat
    21361 tccaacagct agttataaag taacttatga tattcgctcg atggatccag agaataagaa
    21421 agaaacaagt gtgacaatca cacaagtact caatcttccc ttttctattt caaacaaggg
    21481 ctgtcgtatt attgcttatc cttattttac ggcactacca aagaatacag aaaaacaacg
    21541 aatgattact tatgatgaca cattatacga aacggttgat gcgtcggaag cgaaagatgt
    21601 ggaaggattt gtggaagatt tcttagataa gtatgcgaaa aacaatgcaa aagatatgtc
    21661 atacatgatg aaagaacctg aaggactcaa tcagacagct aaagttgatc aagtagagat
    21721 gaaagtattg cgttataaag aaacgaaaaa aacttttatt gtaaaagcaa cagtcgtctt
    21781 tcgagatggt gatacgtcac ttttacaaaa agaacaaatg acgcttgtta ttacgaaaaa
    21841 aacaaatcag tattatgttg aaaaactcac acataattgg ttggatagga aaggagacga
    21901 acggaaatga cactgaaggg aattgtagat tttatattaa cgcaaggtgg ctatttttta
    21961 ataatggtgg ttgtttatct gggattgcga aattttatga aatcaaaagt aggaaatgca
    22021 ttaatatcta tcgcagcagg tgccgcagtc tatttcttct taaatgatcc aacgcgtgta
    22081 tttgatgcgt ttggtaaaat cattgaaaaa ttatttatgg attaggagga tagtgaagtg
    22141 gattgggaac cttacgatta ttcgattgtt tatgcggagc cttatcgcgt acaacagatt
    22201 acaagcaatt ggcgtcttcc atttccagtt gcattagtca atgcagcaac ttttttattg
    22261 gtcgtaatct ttgaatattt atttttacgt tcatttattg gttgggttat ttcttttttt
    22321 ccaccagcag gggttgtttt ttttataggg ctaccctatt tatgtgtgtt agcactggca
    22381 aaactaaaac ctgatggaaa aaaagtgcat ttttatttat gggattggtt ttgttatgta
    22441 gtgcgtatga tgaatggtga ttgtgtgtat tataactggg acaaggtatc aaataatgca
    22501 ttggaagaat tactttttgc gaataagtat gtttatttag aggattagaa aaagggacaa
    22561 tcaactggtt gttccttttt ttaattggga ggtgagatct attggtactt gtaaaagaac
    22621 cagtgaaagc attaaagaaa aattgtttgt taaatggcga ggattgtatc tgggcctact
    22681 atcatgtttt tccacgaacc atttcaaaaa acacaccaaa aaagacacag gaaataaaag
    22741 aaatgatggc tcgtttactg ttacttttag cagattatga agatgtggag ttggtgatgt
    22801 atccacgaac aatgaattta cggacgaaat ttgacacatt aggaaaggga ttttctcccg
    22861 atagtcaagc aattggtgcg tattatgcaa aagaaacagt gacattgttg gaacgagaag
    22921 gtcaagtcta tcgtccttcc tttattttag gaatcaaagt caaagaaaaa gcaaccgtgg
    22981 agagttttta tgatgtacta aatctaatct ggttagatgt agcaggaagt ttagcacgct
    23041 tatttggatt agaagtagat gatttagaaa ctttgttttc tgaaagtgat ccttatgtaa
    23101 aagaagtgac acaattactt tatagctttt ctattcgtcc cttagtaaaa aaagagctgt
    23161 tgtatctcaa tcgtctgcaa tatattcgag gaatggctca taaagtagaa gaacaaaata
    23221 attgggaagt actgaaagac aatcaaggaa cgtatgtacg tatgccgaag gaacataaag
    23281 gccttcttca attagaagat gagttgggga ctagttattt agcgttgtta cctattggag
    23341 aaacacctga aaatatgaga aactgtgatc tatttcaatt tgcacaggat ctttctttcc
    23401 cagcagaatt acgaatgaaa attcactatc cacgcttgaa aggacaggga ggtattggtt
    23461 taaaactaaa ttggctatcg gaacggttca aaacagaata taaggaattg gttcaaaacg
    23521 atgaagaacc tagcgaacgc ttattaactg ttcggggatt agtaaaacat ttaaagcaac
    23581 gagtagataa tggccaacct gtcgtcgatt ggatcgcatg ttttattgta tacggtcaaa
    23641 cggttgaaga agttcgtcaa aatagtgcaa cgattattca acagcttcat acgactatcc
    23701 atatccaccg tgcaaaaaat gatcaacgag aattgttcta taaatgttta ttagggcaac
    23761 cattgggtcg acagttgcat tggaagcacc gaacaactgt agaagcaatt ggcgaatggt
    23821 tgttttcagc agtatcagaa ttaggtatgg aatccggctg gtatattggt cggcaagata
    23881 cattagggga tggtggttct cgaggagaaa aaacaccatt agaagaatta atttatgcgt
    23941 caaatcgttt tgtctttttg aatcttctag ctattgcgga aggaatcaaa ggtgcgttgt
    24001 ttgatgcgcc tcatgtagca gtaactggaa aaaccggtaa agggaagacc tttttagttg
    24061 gattgctctt tttgtatagt tcgtttatga atgtacaaag tttatttgtg gatcccaaag
    24121 gagaaaagcg caaatggttt acgaaactca ttcaagaccc gtattatcag aaacattacc
    24181 ctttgtttgt ggaacatttg caaaaaatga gttatgtcac gttagatgct acaaatcccc
    24241 gtaattatgg cgtattagat ccaattgttt gtttatcccg agtagatgcg aaacaagtag
    24301 cccaggatat gattgatgag ttaagtccgt taggtaccaa tcacctttta aaaggggcgg
    24361 tattaaaggg aatccaagaa gttttagttc aaaaagaagc cggacaacaa gttggcttga
    24421 tgcatgtggt cgagtattta gaacaaatgg aacaaaaaga ggttcgagaa tatggtgagt
    24481 ttttacgctt gacggtagaa gattcgattt tacgtttagg attttcttat ggagaaaacc
    24541 cgggattaga ct
//
LOCUS       DACBZK010000037        24324 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.037, whole genome shotgun sequence.
ACCESSION   DACBZK010000037 DACBZK010000000
VERSION     DACBZK010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24324
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.037"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(16..1170)
                     /locus_tag="IVD66_001598"
     CDS             complement(16..1170)
                     /locus_tag="IVD66_001598"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HAP6145821.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            1355..3796
                     /locus_tag="IVD66_001599"
     CDS             1355..3796
                     /locus_tag="IVD66_001599"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HAP6145822.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(4126..4830)
                     /locus_tag="IVD66_001600"
     CDS             complement(4126..4830)
                     /locus_tag="IVD66_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145823.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(5017..5262)
                     /locus_tag="IVD66_001601"
     CDS             complement(5017..5262)
                     /locus_tag="IVD66_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145824.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(5279..6130)
                     /locus_tag="IVD66_001602"
     CDS             complement(5279..6130)
                     /locus_tag="IVD66_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAP6145825.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            6296..7300
                     /locus_tag="IVD66_001603"
     CDS             6296..7300
                     /locus_tag="IVD66_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAP6145826.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(7541..7897)
                     /locus_tag="IVD66_001604"
     CDS             complement(7541..7897)
                     /locus_tag="IVD66_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP6145827.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            8265..9452
                     /gene="tuf"
                     /locus_tag="IVD66_001605"
     CDS             8265..9452
                     /gene="tuf"
                     /locus_tag="IVD66_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAP6145828.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(9640..12231)
                     /gene="mprF"
                     /locus_tag="IVD66_001606"
     CDS             complement(9640..12231)
                     /gene="mprF"
                     /locus_tag="IVD66_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAP6145829.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(12257..12976)
                     /locus_tag="IVD66_001607"
     CDS             complement(12257..12976)
                     /locus_tag="IVD66_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP6145830.1"
                     /translation="MKKEKKYAKMPDGSEIYYEKSGQGFPLFLLHGNDGSGRFFSEQV
                     PVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEKIDQADFLGFSDGAN
                     LALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVWLLSLFRPSLRKNLL
                     VIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKTIPKASFVLVKEQGH
                     ELARKDPERFNREVLQFLSET"
     gene            13296..13817
                     /locus_tag="IVD66_001608"
     CDS             13296..13817
                     /locus_tag="IVD66_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HAP6145831.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            13876..14736
                     /locus_tag="IVD66_001609"
     CDS             13876..14736
                     /locus_tag="IVD66_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HAP6145832.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            14843..17236
                     /locus_tag="IVD66_001610"
     CDS             14843..17236
                     /locus_tag="IVD66_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP6145833.1"
                     /translation="MFLILEHARLKHVIIFESWRKMEKKKMNGLTQQEVVQKMASGQQ
                     NDYQEDASKSTKQIFSDNILTLFNFLNFGIGICLLFVGAYSNMAYLAIIVVNIVIGIY
                     QEIHARNLVRKLSIVSQSEVLVIRDGKEQSISTKELVLGDLVKIGAGEQIPADLQVIS
                     GRAEANEALLTGESDLIVKETGAELLSGSFLTSGSVMAEVIRVGADNYAVRLTSEAKT
                     HKAIRSELVDSIRKVSKFTSFVIIPLGIILFLEALFIRDASIKISVIASAAALLGMLP
                     KGLVLLISIALTTGVTKLAKKRILVQDMYSIETLAHVDTLCLDKTGTITEGKMSIQRV
                     EALHPLYEKAIPEIMGTYLAESSDNNITMRAMRDYFELSNRYDVTNKVAFSSDRKWGA
                     MEFPELGVVYVGAPERLVEEDRLPDSLKTAQANGYRVLMLGIAPNQQLNEEKPAFVEP
                     VALFEIDDPIRKNAQETLAYLHEEGVDLKVISGDNPFTVSNIARRAGLPNYDAYVDLS
                     QITEEMEVREAAHRYTVFGRVSPQQKKLLVNELKESGRTVAMTGDGVNDVLALREADC
                     SIAMAEGDGATRQIANLVLLDSDFTTLPEVLFEGRRVVNNVTKVSGIFFIKTIYSFIL
                     SIICAVTAIGFPFIPIQITLIDLAIEGYPSFFLSFEQDKRKITYRYLPTALINALPNA
                     LLVVVNIIAVYLLGKTFAWGNAETTTLMYYLLIGISCMAVVKACYPFNPLRIFLAVTT
                     IVGIYVAAMLFHGILEVNLGLGESVGYFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            17418..19259
                     /locus_tag="IVD66_001611"
     CDS             17418..19259
                     /locus_tag="IVD66_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HAP6145834.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRLMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            19283..20392
                     /gene="rpoD"
                     /locus_tag="IVD66_001612"
     CDS             19283..20392
                     /gene="rpoD"
                     /locus_tag="IVD66_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HAP6145835.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            20612..22711
                     /locus_tag="IVD66_001613"
     CDS             20612..22711
                     /locus_tag="IVD66_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAP6145836.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            22907..23770
                     /locus_tag="IVD66_001614"
     CDS             22907..23770
                     /locus_tag="IVD66_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP6145837.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            23875..>24324
                     /locus_tag="IVD66_001615"
     CDS             23875..>24324
                     /locus_tag="IVD66_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAP6145838.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEK"
BASE COUNT         8128 a         4301 c         5035 g         6860 t
ORIGIN      
        1 ctttttatga ttttattata ttttgtagta acgaatatca ttttcgatct ttgtaatcga
       61 aaaaggtaca tctgaagtat attctgcaca ttctccgtgt tcaggaagcg tctcactgaa
      121 aatcgtttca tattcgtcaa cagtgatccg tgttcgagaa tctagcatct cttgatgaga
      181 ttgtgcgaag agatattctt gatagttttc ttccagataa cctgtaaaaa attcacttac
      241 tgcaccagaa ccgtagctga atagaccgat gcgatctcct ggctgtagtg atttcgaatt
      301 ttccagtaga gaagttagcc ccaggtataa tgaaccagtg taaagattac cgattcgtcg
      361 gctgtaacgg atgctttctt catagcgagc cataagacgt tcctgatttt cttcgtctgt
      421 ttggtctaat acgctttgca atgccttttt tcccatctta gtatacggaa tatggaaagc
      481 aatcgcctga taatcttcga gtcctcgacc cgacaattct ttatgtcgat tccaaacttt
      541 ttggaatgat tcgatatacg tagaattaga taaaggacca tcaacaacag gaaattcgct
      601 ataatctgga cgccagaaat catagatatc ttctgtcaga aatacgctgt cgtcttcaat
      661 cgataaaata cgcgggtttt gagtgatcat catcgcaaca gcaccgacac cttgcgtcac
      721 ttcaccaccg cttgccaagc cgtaacgagc aatatcactt gctatgacta gtacttttcg
      781 ttctggatga tttttgacat attctttcgc catgtgcaaa gctgcggtgc caccgtagca
      841 agcctctttt acttcaaaag aacgagcaaa agattggatt ttcagtaaat ggtggataat
      901 taccgcactc gcttttgaat gatcaatccc ggattctgtt ccgacgatga ccatgtcgat
      961 tagctcacgg tctttttctg ttacgatttt gctggcagca tttgctccta gtgtaatgat
     1021 gtcttcattt gcacgattga ctgccatttg gtcttgacca atccctatat ggtattttgc
     1081 aggatcatcc ccacggcttt ctgccaactc tgtcatatct aaatataaat taggaataaa
     1141 aaaggaaaga cgatcaatcc ctattttcat ttcaacacct ctttacttat gataaaaaac
     1201 ttactttact aaggtatcat aaaaagatta aaagaaatat aaaaaagaga atatttaagg
     1261 attgttaaaa tttaatctta gaaaaaaata actggaacaa gagctatttg tttttacagc
     1321 aaagaatggt atatttttgt aggaggtggc ttacttgaaa gaagtcgtta tgatagatgc
     1381 tgcaagaacg ccgataggaa agtatcgcgg aagtttaagt ccatttactg cagttgaatt
     1441 aggcacactt gtgactaaag gattattaga taaaacaaaa ctgaaaaaag ataaaatcga
     1501 tcaagtaata tttggaaatg tcctgcaagc tggtaatggt caaaatgttg ccagacagat
     1561 tgctttgaac agcggtctcc ctgtagatgt cccagcaatg acgatcaatg aagtttgcgg
     1621 atctggtatg aaagcagtga tcttagcacg ccagctgatc caattaggtg aagcagaact
     1681 tgtgatagcc ggcggaacag agagtatgtc tcaagcacct atgctgaaac agtatcagtc
     1741 agaaacaaat gaatatggtg aaccaatttc cagtatggtc aacgacggat tgactgacgc
     1801 attttcaaat gcacatatgg gattaaccgc agagaatgtt gcaacacaat tttctgtgag
     1861 cagagaagag caggatcgct atgccttgtc gtcccagttg aaagcagcac atgctgtcga
     1921 agccggtgta ttttctgagg agatcatccc agtcaagatt tctgatgaag acgtgttatc
     1981 tgaggatgaa gcagttcgtg gaaatagtac attggaaaaa ctgggcacgt tacgtacagt
     2041 attctcagaa gaaggaactg taacagcagg aaatgcttcc ccgttgaatg acggtgcctc
     2101 tgtggtgatc cttgcatcca aagaatacgc agaaaataat aatctgcctt atttagcaac
     2161 catcaaagaa gtagcggagg tcggtattga cccaagtatc atgggaatcg ctccaatcaa
     2221 agccattcaa aaattgacag atagatcagg aatgaattta tcaacaatcg atctttttga
     2281 gatcaatgaa gcatttgcag cttcttctat cgtagttagc caagaactgc agttagatga
     2341 agaaaaggtc aatatatatg gaggagcaat cgcattaggc catccaattg gtgcaagcgg
     2401 tgcacgtatc ttgactacat tagcttacgg attgcttcgt gaacagaaga gatacggtat
     2461 tgcttcatta tgtattggtg gaggtttagg cttggcagtc ttgttagaag cgaatatgga
     2521 gcaaacacat aaggatgtgc aaaaaaaaaa gttttatcag cttacgccat ctgaacggcg
     2581 cagtcaatta atagaaaaaa atgtattgac acaagaaact gcgttgattt ttcaggaaca
     2641 aacactttct gaagagctct ccgatcacat gatcgaaaac caagtgagtg aagtggaaat
     2701 cccaatgggg atcgcgcaga attttcaaat caatggcaag aaaaaatgga ttccgatggc
     2761 aacagaggaa ccatctgtca ttgcagctgc aagtaatggt gcaaaaatct gtggaaatat
     2821 ctgcgcagaa acacctcagc ggctgatgcg agggcaaatc gttctatcag gaaaatcgga
     2881 gtatcaagca gtgatcaatg cagttaatca tcgaaaagaa gagctgattc tttgtgcaaa
     2941 tgaaagttat ccttcaatcg tgaaacgcgg gggcggtgtt caagatatct ctactcggga
     3001 attcatgggg agtttccatg catacttatc tattgatttt ttagtggatg taaaagatgc
     3061 aatgggcgct aacatgatca actcgattct tgagagtgtg gcaaacaagt tacgggagtg
     3121 gttccctgaa gaagagattc tattcagtat tttaagtaat tttgctacag aatcattggc
     3181 ttctgcctgt tgtgaaatcc cattcgaacg cttagggaga aacaaagaaa tcggtgaaca
     3241 aattgccaaa aaaatccaac aggcagggga atatgcgaag cttgaccctt accgtgcagc
     3301 aacgcacaac aaagggatca tgaatggtat agaagctgta gtggcagcta caggaaatga
     3361 tacacgtgcg gttagcgctt cgatccacgc ctacgcggca agaaatggat tataccaagg
     3421 attaacagac tggcagatca aaggggataa actagttgga aaactaacgg tgcctttggc
     3481 tgttgccaca gtaggcggag cttccaatat cctgccaaaa gcaaaagcat ctttagctat
     3541 gttagatatt gattcagcca aggaactagc acaagtaatt gctgcagtag ggttagctca
     3601 aaacctggct gctttgcgtg cattagttac agaaggaatc caaaaaggcc acatgggact
     3661 tcaagctcgt tcattagcga tctcaattgg ggctattggt gaggaaatcg agcaagttgc
     3721 gaaaaaatta cgtgaagcag aaaagatgaa ccagcagaca gctatacaaa tattggaaaa
     3781 aatccgggaa aaataaaaaa gcaatatctt tagaagaata aagcaagatt tacagttatt
     3841 ttatttactg cagatcttgc ttttttctct atcagaaaat atgtttatta ttagaatttt
     3901 ttatagttaa ggttaggcat cttaagaaat caggcaactc caagatatct tcaggtagaa
     3961 gagaagtcgc ctaacattgt aggatcatag gtgatttgtt ggacaggtca agctgatatt
     4021 tgagcctgat gttagaagga atttcttttt acttgctgta gaaattatta tatgactaaa
     4081 aaggctggga ttttaaatcc cagcctttta tgacaaatag aatttttatc gatcagtaat
     4141 cgctgtcgct gcaaattgtt cgatcaaagg aatcaaagtc aatttgactt tgtatttccg
     4201 ttcgagtgct ttttcgataa cgaactcatt ttcagtagtc atagaaatag ttgctaattt
     4261 acgaggttca tcagcatttt tttcattaat aactacttca tgttcatttt gttctgtgta
     4321 aaatttagga tactcagcaa cggcttttga aaaatcagca aaacttaaag cggcattcgt
     4381 atcagttgag cgtgtatttt cagttgtgtc cgcttttggt ttttccgttt tttcttctgg
     4441 cacactgact gtttcttctg taactggtgt cgcaacagct tgcgcagttg gttcatcgtt
     4501 tttcaatcgt tgatcattcc agtaagacac gatttcaata agaagattgt cacggaatcg
     4561 ttcgaaaatc ccgttttctc ctgaacgaat tctctttaat acagtattga agttgtcatc
     4621 gattggcacg ttgatccgtg tatcttcatt tgttttccca gctaatccga tcgttaagat
     4681 ttgacggttt ttgggatcaa gcatgacttg taacggcaaa ccataacgtc gcaagctctc
     4741 ttcttctaga gaacggaata attgtcctct tacaccatcc aatgaaggac ggaattgatt
     4801 taataatttt tgtttctgtt ttttcttcat atgttctctc cttcgctcat accctttcga
     4861 ttataagaaa aaaacagcca aatgaaaagg agtaatgcaa aaaaacttgc gtatacgcaa
     4921 attacaacag aaaaatttgc gtattttccc gttttttgaa agaaaaataa aaaatggaac
     4981 ggattatgta tatatacata atccgttcca ttctttctat tttttcggta tcaaggcaaa
     5041 aacaggtagt tcaggtgaat aaatgacttc atgttcgtgc cagggtttga ccattagcga
     5101 atgatcgaac cgttttttca gttcttcgat gatttgatca tgtgtccagt ttcttgcagg
     5161 aaaatgttgg attttctctg catcgatcaa aaagacaaaa tcggaatgaa aagtctgggt
     5221 aacttcttcc gagagagaat tcaagcgttc gattggatcc ataaaatcac ctttcgactt
     5281 aaaattgggt agtatctggg tcttttgctt tgccgactac accatctaac tgatcgattt
     5341 gtttcatttc ttcttctgtt aattcaaaat caaataattc agtattttct ttgattctgc
     5401 ttggtgtcac tgacttagga agaggaagga attcgtgttg cagcgaccaa cgcaaagcaa
     5461 cttgtgcaat cgtcttgtca tgtgcttcag cgatttgttt catttcaggc acatcgaaga
     5521 ttttaccagt gcctaatgga ctatatgctt cgaggatcat atcatgtttt tttgcatact
     5581 caactacagt tgtctgtaat tcgcctggtg caaggaaaac ttgattgacc atcggcataa
     5641 tttttgctgt ttttgctagt gtatctagat ggtggggtaa gaaattgctc acaccgattg
     5701 ctttgatttt acctgcttca tacagttctt caaatgctcg ccatgtatct gcatttgctt
     5761 gttcccaatt atcacgaaaa gcaacagggt ttggccagtg gatcaaaaac agatctaaat
     5821 aatctgtttg gagcttcttc aatgattctt caaaagaaga catcacaagt tcatagctgt
     5881 ggtttgcatt ccataatttt gttgtcaaga atatctcttc tctaggaatt ccactttcct
     5941 taatcgcttg gccgacgctt tcttcattct tgtatccttg ggcagtatcg atatggcgat
     6001 aacctgcagc cagcgcttct ttaacagagg aaacagcgac atccccatca ggtgtttgcc
     6061 atgtgccgaa tcctactacc gggatttcgt aaccatttga tagacgataa gtgcttgtta
     6121 atgaattcat actttcagct ccttttttat tcgttcaact ataagtgtag cgcatttttc
     6181 gaaaaaaaga atccattttg tttctactct tgaaattttt gtttaaaaga aaatgatttt
     6241 gattctggta tttttgattt tttttccgta aactaagaca gaagggaatg agaaaatgga
     6301 tatctattta aaaaaagcaa ttctgcatat tattgacaga gaaactggtt ctccagtctt
     6361 ttcacaaaaa gagctggatc tgacaaaaga atatattcgt gattttcttc aaaagaagat
     6421 ccaaaaaatc tcttctgctc aaacaaaaac tggacaacta gcagaagaaa gcatgatcgt
     6481 tgaatcactt aaaatcgctc aagaaaattt tgtggaagca agtgaagcaa tcgttcagcg
     6541 gtggttcgat atctaccaag aaagtgaaga agcacctagt gcagatgtat ttgttgtctt
     6601 gtatgaatta gatacagtga tgtacttatc tttattgaaa gtcaattatc gtgaggctta
     6661 cactcacttt gttgaagcag acgaagcagg gatcgacaac cgcttgattt tgaatcgagc
     6721 aattctaggg gcgaaaacac aaaaagcaga tgaagcattc gctgtgaatt tgactgattg
     6781 gacctacgaa ttaattgaaa aaaaatatga gttttctggc aaaaaagagc tttatttttc
     6841 tggaagagtg atcgaaagtg ttcctgcacc ttctttagaa gaaaatgtaa aagtgatcca
     6901 aaaagtagcc aagcatcttg gaaaaaaatt tgagacagaa gaatttgata tcatggctga
     6961 tttgaaagaa gctgtctatg atacgataga agaaaaaggt cggttggatc atgagatgat
     7021 tgcggaaaaa gtcttcaagg aaaacatcac ggcaaaaatg gcttttaaag aagaagtaca
     7081 agagcaagga tttgtcccag aagcacctcc tgtaaaagaa gtacaagaaa tttctgagaa
     7141 aaaatttgga aaacaaaaat tcaagctatc aaacgggatc gaactgatcg taccagtaga
     7201 tgtatatcgc aacccagatt tgattgaatt tgtgaataat ccggatggta cgatatccgt
     7261 gatgatcaaa aatgtggatg aagtattgaa tcgtttataa aaatgactag aatattaggt
     7321 gttcaagtac cagtgatcag ttaaatgaat tgtgtcaaga gaaggatcgg aaaagacgaa
     7381 tataacaaaa aaagagcgtg agacaaaagt aaagaacact tttgtctcac gctctaaaca
     7441 cgtataaacg gcggaagcag aagcaactcc ttcttatttc ttggagttaa acgcttctgt
     7501 cccagcctct ttttatctaa taaaatttta agaccattta ctaattatcg attttttctg
     7561 ccgcattttt aggcacttca gaagccttta tttcttccca gcttaataca cctttacgag
     7621 gattgacttt gagtttaaga tacgcattca tctttaatgg atgttctctt tcttcgcgaa
     7681 gcgtcacctg ttttttttca ccatctttat tataagccgc ttgcttgtag gtataagtcg
     7741 tgaatttctc tccgttatct gcttgggtag ctgacatttc gccattcgtc gtgatttttg
     7801 tataataagc ttcgccgccg taaaaataat gataagctgc aaaacttccg ccgagaaata
     7861 tgcctaaaac gacaagtacg ccaattaatt ttttcatgta cttcacctct ttccttatta
     7921 ttaacgaaat agaagatttc gtctattgaa agttgttggc aacagctgaa ttttaaactt
     7981 ttcctcattt tgttcttatt gcttcaaaag aaagttaagg actatcttga agtttttctc
     8041 aaaaaacaca tttttttatt tataaaaggt acttttttcg cgtataagac agacgagtgc
     8101 tcttagttga ctttgaccaa tattgacgta taataagctt agttcgaatc ttacaaaaag
     8161 taagtcggac gtattctttt tgatttagtc aaaaaaagac tataataaaa aggtgagagc
     8221 tgaaattttt cagtgatcta tattatttag gaggtttgta aattatggca aaagaacatt
     8281 atgacagaag taaaccacac gttaacattg gtacgattgg acacgttgac catgggaaaa
     8341 ctactttaac tgctgcgatc actacagtat taggcaaaaa aggcctagca aatcctcaag
     8401 actatgctag tattgatgca gctccagaag aacgtgaacg tgggattacg atcaataccg
     8461 cacacgtaga atatgaaaca gaaaaacgcc actacgcgca tattgatgca ccaggacacg
     8521 cggactatgt gaaaaacatg attacagggg cagcacaaat ggatggtgca atcttagttg
     8581 tttctgcaac tgacggtccg atgcctcaaa cacgtgaaca cattttattg tcacgccaag
     8641 ttggtgtaaa atacctgatt gttttcttga acaaagttga tttagtcgat gatgaagaat
     8701 tgatcgattt ggtagaaatg gaagttcgcg agttattgag cgaatatggt ttcccaggcg
     8761 atgacactcc tgtgatcaaa ggttccgcat taaaagcatt gcaaggcgat ccagatgctg
     8821 aagctgctat tatggaattg atggatacag tagatgaata tatcccaaca ccagaacgtg
     8881 atacagataa accattacta ttgccagtgg aagacgtctt ctcaattaca ggtcgaggaa
     8941 ctgttgcctc aggtcgtatt gatcgtggtg ctgttcgtgt cggtgatgag gtagagatcg
     9001 tagggatcaa acctgaaaca caaaaagcag ttgtaacagg tgtagaaatg ttccgtaaaa
     9061 cgttagatta cggggaagct ggggataacg taggcgtgtt gttacggggg atccaacgtg
     9121 acgatatcga acgtggacaa gtacttgcta aaccaggttc cattactcca catacaaaat
     9181 tcaaagcaga agtgtacgtg ttgacaaaag aagaaggtgg acgtcatact ccattcttca
     9241 acaactatcg tccacagttc tacttccgca caactgatgt tacaggaaca atcacattgc
     9301 cagaagatac agaaatggtc atgcctggtg acaacgtgac gattgatgtt gacttgatcc
     9361 atccaatcgc tgttgaaaac ggaacgacat tctcaattcg tgaaggcgga cggacagtag
     9421 gttcaggtat cgttacagag atcgaagcat aagaaacgcg actcgaatat tttggtaatg
     9481 aaaaatgttt aaaataaaag agcggtccaa acaggatttc tgtttggacc gctctttgtt
     9541 cttcaattgt ataagaagag attgtagaag catgaacttt cgttttactt cagtctcttt
     9601 tattcatcat gagagtgttc atctatcggt atgcagtttt taatactttc ttcgtatcca
     9661 ttttttcaaa ccacttattc taccttgtgt ctgctcaact ggcgcattat caataatcag
     9721 caaagcaatc ataacatatg caatccaact atctctagaa tatagagtat aacgtgagac
     9781 ccagtttgta gcgtacttgc ttttatattc tcttaatcca tggaaagaat aaaaatgaga
     9841 accaaactcg taaaccaagt atgcaatcct ttcctgtaaa aaactctttc tggaagttcc
     9901 gacatttgaa agaggggcca tccctaaatt gaaccattgg atatgttctt ctttcatata
     9961 ggcaaacaaa tgcaagaaca agaaatccat actgccagaa ggtgcttttt tagaatcata
    10021 tcgcatcaga tcaatcgttc ctactttatt gttcgtgtaa gtaggcatga tcgttgcaaa
    10081 agcgacaatt tcttcttggg tatttttgac aactgcaata ggcgctcttt gtagataatc
    10141 ttcagagaaa aagcctaaag aaaacccttt ttcctttcgt gaacccaacc aattatcaga
    10201 gatatttttg aaagtactca tttgctcagt agaaaatggt ggttgtaaga catcaaatgt
    10261 aaatccttct cgttcgatcc gattcaagac agcacgagtg cccttcattt ttttccctga
    10321 agttgtaaaa ctattcaggt ctacataagc ttcttccccc atcttaatga aatcgtagcc
    10381 gaattcatgc aaaatcataa caatctcttc gcttgtttcg tagaaaactg gtaaatagca
    10441 tagtcgatct gtttcttcga taaaagcttc gattgcttct ggaaaatctt ctttcttacc
    10501 agaaggatca cccattacaa tacatttatt attgaagcaa gcgaattgga gaagaacagt
    10561 tggttcaccg tctttttcat aggcaaacat ccgcttatct tttaagaaga tcaattgact
    10621 atcggagttt cctccataag ttgtaaggat cttcagggcc ttttcttcat taaaggcttc
    10681 gccaatctgt ttcttttctc cttgaaggaa atgaacaaat agaacgatca tgaaactaac
    10741 agcgatgatg gccaacaatc ccgaaaacca aatcttttca gaaggaaata agaaaaagga
    10801 aataaaatgg tgacgccgat gagggaaatc cggcagattg tataccccaa taacgatgta
    10861 aagcaaggac agtgcaccaa taatgattcc atcgatcgta cgccactccc atgaatagat
    10921 caattgttcc cgaaataatt cgtttttaga agcaagaatg atcagaagca gaatagacaa
    10981 gaaaaccacc ggtgtgaaac taaaatcact taataaaaca taaagtaaag ctagaacaat
    11041 caagaagatt gtaggcaaat atgctcgttt cacacgtgct gcgatccctc tgcccataat
    11101 gattaaaaga aatcccaata gtatactagg aaattggata ataaaatgaa atttcaatgg
    11161 gttcaaacta tgaagccagc gaaactctgt aaaagcttgc gggatagtgg cagaaagtac
    11221 tagcatgatt ccagaaaagt ataataagac aaccacgatt ttatgcgcaa tttctgttgc
    11281 taattgttta gggataccag aataacgctg atcaaaagtg gaaccgatat ttttgaagaa
    11341 aaagacgatt ccaatcaaaa acggaatgat gtagtagaac aggcgataga gcaagatcca
    11401 cacaacgact atttctcttg gcacaccaat agcggacaac ccgataatca tcattacatc
    11461 gaaactccca atttctcctg gaatcataga cacgattcct atcactgaag cagcaatgaa
    11521 taatggaatt gtttgccaca gatcaatccg gatttccatt aaataaccaa cagaaaggaa
    11581 actaaacagg acaccggtcc attccaacaa tgaaactagc aatagctgtc cttgagtttt
    11641 aagtgaggta ccaccaagga atcctttctt tttgaaagta gtaaataaaa agacgacagg
    11701 aaaatataga ccgccgccga tcaaccatat ccaatattgc ttcaaaaaag gagcaactgg
    11761 cgtgaagact acaagtaaaa aagaaagcag actgtaaata gaaagtccag ccatcaaaaa
    11821 caagaaaact ttcgataatg cttggatcac gtttctgctc tctttctttt gtccatatag
    11881 ttcagagcga agccccacac taacaaaccc gccgaaaccg gcaatattgt tgatcgtatt
    11941 gatcagccag cttgtctcaa acaggtaacg aggattctgc ttttgttcaa gcatccgatt
    12001 caaaataata tcataaccaa ccataggtaa cacagagata agaccaatca atagcattag
    12061 tccgcttttc catacaggta tagtggcaaa cgtttctcct aattgctgga tagatagagt
    12121 tttaccgatg gacatcaatt caccgacaat aatgacaatg acagaaatca aaaagattgt
    12181 tttgaacagt cctaggtggt ttttcagcca ttgtatggta ttttttaaca aataaatcac
    12241 cttctattcc taatagttat gtttcagaaa gaaattgaag aacttctcga ttgaagcgtt
    12301 caggatcttt tctagctaat tcatgtcctt gttctttcac aagcacaaag gaagcttttg
    12361 gtatagtttt agctatatac aaagaatgtt ttagcttgat tacatctttt tttcccacga
    12421 tgatcaaagt gggggagttg atttttttta aatcattttc tgtaagcccg atgtcatgca
    12481 gcaaaagttt gataactaaa agatttttgc gaagacttgg gcgaaataaa gagagtaacc
    12541 atacccatgc ataatgaata ttactgatga ctctggcaga aaaacgaacg cctttaacaa
    12601 gcgtgtttcc agaatttaaa atcaatcgat gaactttttt agggaagctg ctggcaaata
    12661 ccagtgctag atttgctcca tcactaaatc caagaaaatc tgcctgatcg attttttcca
    12721 gcaacatgat cgtattcaga tcctcggcca ttaactgaaa attcaacata gatgcttcgt
    12781 ttgtcgaacg accatgtcct cggctatcta ctagatacac ggtatagtag cgttcgagta
    12841 cagggacctg ttctgaaaaa aagcggccgc tgccgtcatt gccatgcagt aaaaagagag
    12901 ggaagccttg accgctcttt tcatagtaaa tttcgctccc atctggcatt tttgcatatt
    12961 tcttttcttt tttcacataa tcacctactg tgtaaagtat aacgattata tcagtcattg
    13021 ggcaattgtt tttactgaaa aacaacgatc attttcgtaa gatgtcaaaa aatacaggaa
    13081 aattcatttt ttcttaaggc gtacacagaa atcaaggaag aaatagccaa gaagataaag
    13141 aaatagtaag ataaaaaaag atgtcaaaat aactaggtga tgaaatgaag cgaaaacgat
    13201 tatctattat ccgtattctt ttttacatga tcattctgac ggttattggt gcggtgttgt
    13261 ttttatgagg aagaacttat cgttcggtaa aacgagtgga aagctatcaa atagaaataa
    13321 caacagctgc aaaaaattat catatggaaa actacgagaa tttgatcaag gcgataatat
    13381 tgaccgaatc aaaaggaaaa gggacagatc tcatgcagag ctcggaaagt ctgcatggag
    13441 aagctgagat cattgataat ccagctgaca gtattgatca aggtgtcaaa tatttggcgg
    13501 aaatgatagt agaagcaaag aaacaaggat gcgatttatg gacagctgtc caagcatata
    13561 attttgggaa agattatatt gcctatgtaa aaaatcatgg cggagaaaac acagtagaat
    13621 tagcagaagc gtattctaaa gatgtgctga gcccactttt aggaaatgag gaagggaaac
    13681 aataccgata ttggcggatc cagtccttgc tttacaatgg cggctatctc tatcataatg
    13741 gaggtaacat gttttatcct gatattgtca aaatgaatga aaaaataata gagacctatg
    13801 aaaaagtctt taagtaaaat agcaggaaat gttcaatcat gaataaaatt aaatgaaaga
    13861 aggagtgcgc aaatagtgga aaaaaggcaa aaaatggaaa atcaagaagt ggggtacaca
    13921 accaaagact ggatgttacg gtttgtgaag ggaatgttta tcggttcagg atttatcttg
    13981 ccaggagtca gcggtggtgc attagcagct gtctttggca tgtatgagcg gctgatttct
    14041 tttttagccc accttacaaa aaatttcaaa gaaaatgttt tgttttttct gcctgttggt
    14101 ctaggcggag tgacaggcat ctttctactt tcttttttag tcagtttttt attaggtgcg
    14161 tatgaaacaa cgatattatg gttttttgtc ggatgtatcg ctggaactgt tcctgcgtta
    14221 tggaaagaag cagggaaaaa aggaagagat acttctgatg tgatcatcat ggttgttact
    14281 tttgttctgg cttatttgtt tttattatac ggcgctcaat tatttgacgg gcaagtcgat
    14341 cagaattttg gaacatggct gattgccggc ggattgattg gtttgggtat gatcgtccca
    14401 ggattgagcc cttctaattt tttggtgtat atgggattgt ataaagcgat ggctgacgga
    14461 tttaaagaag tacgacttga agtgattgtg ccgatcggaa ttggtgggat tctttgtgtt
    14521 cttggattgt caaaaatcat ggattacatt ttctcaaagg catatagcaa gctattccat
    14581 ttcattttag gtgtagtttt tgcttcaacg attatgatca ttcctaccga ttacgcggga
    14641 ttgggagttg ctggggtact agcttgtcct gttcttttta tagccggtac agcactaggt
    14701 tggtggatga gccgtttgga ggaacaatat aagtaaagat agattgataa taaaaacagc
    14761 acacgggtga ttcaaacaaa aaggttggca tcttttttgt aaaatcattc gtgtgttttt
    14821 ctataaattt tataaaaaca agttgttttt aatcttggaa cacgctagac ttaaacacgt
    14881 gattattttt gaaagttggc ggaaaatgga gaaaaagaaa atgaatggac ttacacagca
    14941 agaggtagtt cagaaaatgg cttctggcca gcaaaatgac taccaggaag atgcatcaaa
    15001 aagtacaaaa caaatattca gcgataatat attgacgtta ttcaattttc tgaactttgg
    15061 tattgggatt tgtctgttat ttgtaggtgc gtattccaac atggcgtatt tagcaattat
    15121 tgtcgtcaat atcgttattg gaatttatca agaaatacat gcaagaaatc ttgtacggaa
    15181 attatcgatt gtttcccaat cagaagtact agtgatccgg gacggtaaag aacaatcgat
    15241 ttctactaaa gagctggtat taggagattt ggtaaaaatc ggagcaggag aacagatacc
    15301 agccgattta caggttatat ctggacgggc agaagcaaat gaagctcttt tgacaggcga
    15361 atctgatttg attgtcaaag aaactggagc tgaattgctt tctggaagct ttttgacaag
    15421 cggttctgtc atggctgaag ttatccgagt aggtgcagat aattatgctg tccgcttgac
    15481 tagcgaggca aagactcaca aagctattcg ttctgaactt gtagattcga ttcgcaaagt
    15541 atccaaattc actagtttcg tgattattcc tttggggatc atactatttt tggaagcact
    15601 gttcatccgc gatgcttcta tcaaaatttc tgttattgca tctgcagcag ctttgttagg
    15661 catgcttcca aagggtttgg tattgctaat aagtattgca ttaacgacag gggtaaccaa
    15721 actggcaaaa aaacgaatcc ttgttcaaga catgtattca attgaaacgc tggcccatgt
    15781 cgatacatta tgcttggata aaacagggac cattactgaa gggaaaatga gtatccagcg
    15841 ggtagaagca ctacatccgc tgtacgagaa agccatccca gaaattatgg ggacgtatct
    15901 ggcagaaagc agtgataaca acatcactat gcgggctatg agagattatt ttgagctttc
    15961 taatcggtat gatgtgacaa acaaagtcgc attttcttct gatcgcaaat ggggcgcgat
    16021 ggaatttcca gaactgggag tcgtgtacgt aggagcgcct gaacgtttgg tggaagaaga
    16081 tcggcttccg gacagtctaa aaacagccca agcgaatggc tatcgcgtac ttatgttggg
    16141 gatcgctcca aatcagcaat tgaacgaaga aaaaccagca tttgttgagc cggttgctct
    16201 gtttgaaatc gatgatccaa tccgaaaaaa cgctcaagaa acactagctt atcttcatga
    16261 ggaaggtgtg gatctgaaag tgatttctgg agacaatcct tttactgtct ccaatatcgc
    16321 tagacgtgca ggattaccga attatgatgc gtatgtcgat ctttctcaaa ttactgaaga
    16381 aatggaagtg cgagaagctg ctcatcgcta tacggttttt ggacgagtga gtccgcagca
    16441 aaagaaattg ctggtaaatg aattgaaaga aagcggcaga acggttgcaa tgacaggcga
    16501 cggtgtgaat gatgttttgg cgttaagaga agcagattgc agcattgcta tggcagaagg
    16561 tgatggagca acacgtcaga ttgcgaatct ggtattgttg gactctgatt ttactacatt
    16621 gccagaagtc ctgtttgaag gacgccgagt ggtcaacaat gtgacgaaag tctcaggcat
    16681 cttttttatc aaaacgattt attcatttat tttatcgatt atatgtgccg ttacagcaat
    16741 tggatttccg tttatcccta tccaaatcac gctgattgat ttagcgattg aagggtatcc
    16801 ttccttcttt ttatcttttg aacaagataa aagaaaaatc acttaccgtt atttgcctac
    16861 agcacttatt aatgctttac caaatgcctt gcttgtagta gtgaatatca ttgcggtgta
    16921 tctacttgga aaaacattcg catggggaaa tgctgaaact actactttga tgtattactt
    16981 gctgattggg atcagttgca tggcagttgt aaaagcttgt tatcccttca acccattgcg
    17041 catcttccta gcagtaacga cgatcgtagg gatatatgta gctgcaatgc tgttccatgg
    17101 aattttggaa gtaaacttag ggttgggaga gagcgtagga tacttctttg tattcatgct
    17161 cgtaaatatt gttcttcgag tattgtactg gaaggctgat attcaaaatc agttactgaa
    17221 aagagtagca aattgatgct taatgagata gaaatgtgtt atacttgaaa aagcaatgaa
    17281 atatgataca atcaaacatg tataattgtg tcctttaaaa tcgcactgat ttcagttagt
    17341 gcgatttttt accggttatt ctcctgaaat atcttctgtt aaacccaaaa gatatcaata
    17401 gagcaggggg tgaaaaaatg gctcaacgga ttcctcaaga ggttatcgaa acagtacgca
    17461 gtcaaacgaa tatcgttgag gtgattggac aatatgtcca gttgaaaaag tctggtaaaa
    17521 attacttggg gctgtgtcct tttcatgaag aacgtacacc gtctttttct gttgcagaag
    17581 acaagcagat ttttcattgc tttggttgtg gtaaaggcgg aaacgtgttt acttttcttc
    17641 aagaactaga aggtctaagt tttccagaag cagtggtaaa agtggcagac ttcgaacaga
    17701 taccgttaga agatcaatgg cgtcagcgta ctatagctgt ccaaaatcct gaatctgcta
    17761 cggggaaact gattgctgct catgaaaaag cagcggaaat ctatcatcac atgctattgc
    17821 atacaaaagc tggacagcca gctttagaat atttgcaaag tcgtgggttg tctttagaat
    17881 taattgaaga attcaacata ggttttgcac ctaatgagcg ttcttttctt cagcaagtat
    17941 tcaagaatga atcaatttca aatgaattgt tagaacgctc tggattgttt gtcacgcatg
    18001 atgatggccg tatgtctgat cgtttttatc aaagactgat gtttccactt cgtaattctc
    18061 aaggccagac gatcggtttt tcaggacgct ggcttgcacc tgaaaaaggg caggaaaaag
    18121 atcagcccaa atacttgaat agtccagaaa cagaactgtt caataaaaga caagttttat
    18181 ttaatcttga taaagcaaga agcgatatcc ggaaaaacgg agaaattttg ttgttcgaag
    18241 ggtttatgga tgtgattgct gcatggcagg ctggtatcaa aactggatta gcttctatgg
    18301 ggacaagtct aacagctcaa cagatccaac aaatggaaaa gctgacgaaa gaattggtct
    18361 tttgctatga cggagacaac gcaggttttg aagcaaccaa tcgagggatt gaattgcttc
    18421 ggcaaaacag tcgattagca ctttctgtcg tagtcgttcc agaaaagctt gatcctgatg
    18481 aatatctccg taagtatgga gaagcatctt tccaagaatt agtggctcat gggcgcgaaa
    18541 cagtctttac ttttaaatca cgttatttaa aacaagggaa aaatttagat aatgaaaaag
    18601 acaagatcga atacctcgaa gaattactag ttgaacttag ccgagttgtt tcaccaatcg
    18661 aacaagatat gtatctatct caactgtcaa cagagtttca gatcggcaga gagacgatac
    18721 aaaaacaact gcgcgatctt cgaaggacaa atcagcaaaa tcgtcaagaa cctcaggaaa
    18781 gtcaacacac tcaggttacg agacaagaaa ctgcacggaa aaagagacct ttgacgcaag
    18841 tagaaaaggc agagcagatt ctattatatc gtgcatttaa agaagtttct gtccgtaata
    18901 ttttaaaaga acgagaattt cagtttattc atgatgcata tgcagaagtt tattttttat
    18961 tcgatgcata tgtctcacaa cattatgaat tcaaccttgc agagttttta gactttttgc
    19021 aagatgaaaa tttaaggcgg ttggtggtgg aaatcgaata tttaccggtg gcagaagaaa
    19081 gttcgccacg agaaatccaa gacttgctag atgtgatcag caaatctggc ttagctgatg
    19141 aaataacatt aaaaaaacaa atgcagcaag aagccagacg aactggaaac aaacagcttg
    19201 agcttgaatt gacgattgaa atcatcaatt taacgaaaca gttaaaacaa gccaaatagc
    19261 tactcaaggg gggccttctt ttatggcaaa tggaacagat aaaaaaacgt atgaagcagc
    19321 agtagcagct ttcatcaaag aaaacaaacc caaacgacaa gttgtatatg atgatttatc
    19381 caatcagctt gctacaccat tcactttgaa tgcagatgaa atggacaaat tgatccaaaa
    19441 gattgaagac gcaggtatca gtgtggtgga tgaaaatggt gatccatcaa ttcacagctt
    19501 gaagagtgct gagaaaaaag ctgaacaagc aaaaacagaa gatctttctg cgccaaccgg
    19561 tgtaaaaatc aatgacccgg ttcgtatgta tctgaaagaa attggccgtg tctccctttt
    19621 aactgcggaa gaagaagtag cgttagcatt gaaaatcgaa gaaggcgacc aagaagcgaa
    19681 acagcgtctg gcagaagcaa accttcgttt agtagtaagt atcgctaaac gttatgtagg
    19741 acgaggcatg cagttccttg acttgatcca agaaggaaac atgggactga tgaaggcagt
    19801 tgaaaaattt gactaccgca aaggatttaa gttttcaacc tatgctacat ggtggattcg
    19861 tcaagccatc actcgagcaa tcgctgacca agcacgtacg atccgtattc cagttcatat
    19921 ggttgaaaca attaataaat tgatacgtat ccaacgtcaa ttgctgcaag accttggaag
    19981 agaacctacg ccagaagaaa tcggtgcgga aatggatctt ccaacagaaa aagtccgaga
    20041 aatcttgaaa atcgcgcaag aacctgtttc ccttgaaacg ccaatcggtg aagaagatga
    20101 ctctcactta ggtgatttca tagaagacca ggaagcaaca agtccagcag aacacgcagc
    20161 ttatgagtta ctaaaagaac aattggaaga tgtactagat acattgactg atcgggaaga
    20221 gaatgtcctt cgcttacgtt ttggtttaga tgatggccgg acgagaacat tggaagaagt
    20281 agggaaagta tttggtgtta ctcgggaacg tattcgtcag atcgaggcta aagcattaag
    20341 aaaattgcgc catccttctc gttcaaaaca attaaaagat ttcttagaat aagcgtggac
    20401 tattgaccag aagagaaatc agtaaaactg tttggtttat tttaaaagaa aaaaagcttg
    20461 agactacgca gtctcaagct tttttttcta taggaaggaa attcattcat tatttttaag
    20521 taaatcctaa aaataagcta ttggcgtgac gtatagaata tgatagatta aatggtagcg
    20581 taaacctagt aaaggagccg atcgctaagt gatgaaaaaa tgtccaaatt gcggatcgaa
    20641 aaaaatggag cagaatacta tctgtccaga ctgcggtcat caaataactg cagaagatca
    20701 gcaaataaaa gaatcaattg aagaaacaaa tacagatgca gctatgcagg ataaatcaac
    20761 tgaagatgca gtctttcctg atacagaatt aaacgatcca atcgaatggt cggaattgaa
    20821 agatttacct ctagaatctg taatggaatt attcgaaaaa gcagaaccag aagacgaaga
    20881 accacctgct cacgatcaag taactaatat agagaaaaat gaacagaaga aagcaactgt
    20941 tcatgagact tcggaagaat caggaaagaa tcaagaagaa acgcttgaat caaaacaaaa
    21001 aagaagagta gctgaactga aagaaatcgt cgataatgag gaagaaaatt cgatactatc
    21061 cgcttatatc aaagcacatc gtgaagatac aaaagaagag cacgcgaaag agctgctcaa
    21121 aatgatcagt gaaaaaattg cacaggaaaa caaagtagag ccagaaaagg aacaagaaac
    21181 tgaaaaagac tctgatagag aaaacgccac aggtaaagaa acagtaaaaa taaaagacgt
    21241 aaaaacggat atcacagaaa aaactgaagt atttactgaa aaacaattag aaaaggaaaa
    21301 aacgaataaa ctgccggaag cagagaaaaa agaaatactc gaaaacacag acaaaaagtc
    21361 aacagagccc gatgaaataa atagtgaatc cgatgctgaa aatcaatctg taagcaaaga
    21421 gggtactgat cttgaagcaa aaatagaaaa agaagagaac cagcctaagc tgtttgaagc
    21481 agaagcgaaa tcaataacaa tcgtgccaga tactgaaaaa acacatcaag aatcaaactt
    21541 agaaaaaaca gatccagata aagcgcaaaa gaaaaaatca aaaaaagtac cttatctcgt
    21601 tttagcagca gtacttctac tcggtggagg aagctgggct tattatgacc atcatcaaaa
    21661 agtagaagcc gaagtagcag cagaagcaaa aagacagcaa caaatggaag aacttcatga
    21721 gaaacttgct gccttttata cagatgatca ccatcaattt attcgtgcag atatgattca
    21781 tcaagattta tcaaaactaa aaaatgattt atccagtctt aagaatgaaa aaggatattc
    21841 agagttagaa acaacttacc aagatatcca atctaagatc cgagatatcc aaaaagtgaa
    21901 tgagtggttc atagcacctg ccatcgtcga tgatcatcta gcagatgaca tcaagttgaa
    21961 agcagataaa gagatccaag caatcgaaac ggataacaca gattttggaa aattgattca
    22021 acaagcacaa acagaagcta aaaatcaata tgctgaattg caaacagcta aagaaaaaac
    22081 agctatagtc tttaaagacg gaaaagtagt ggattcagca acacgcgacc aatacaagac
    22141 ggcaaaagaa gcagtagaaa aagtgaaaaa tacagatcta tctgctcagt tgaatgaaca
    22201 attgaaacaa gtagataaga tgctcactga taaagagaaa aaagaagaag aggaaaagaa
    22261 aaaagcagaa gaagcgaaaa aagcagctga agaacaagca aaacaagccg ctcaagcagc
    22321 agctgcagct caagccgctc aacaagctgc ggtcgcacaa gcagcacagc aagaagcggc
    22381 atcctcgacc ccttcctctt caaactcagc gaatcagcca atcaaatctg ccagagcaag
    22441 tgatattgcc gatgcatcta atccagcatg gacgtgggca ccaggtgtcc aaagcaaagt
    22501 gattgctaca tgtatccaac gtggatatat cgttgaagga ggttacagat tagaaaaagc
    22561 cagaatcgaa aatggggaag gctattataa tctatatgcc acttcaacaa aatctgcatt
    22621 gatgaaaggc attggagaaa gtgctttgcc attttacatc gtaaccatca actgtaaaac
    22681 tggatggttc ggaggaaatg ggagcaatta attttaggca aatgaaagag gctgtgagcc
    22741 tgccgtttaa caccgtttat tcgaaaaagg ggagtatgac acaactgttg tcatactcct
    22801 tttttcacct ttccaaacca aggctcagct attcaagtag ataacattat gttatgatag
    22861 caaagaaatg tattaagaaa acctttcact atagagggag aaaaaaatga acgatttatt
    22921 agcaactata tttacaggta ttattattga tgaaaatgaa aaaaactact ttgtccaaaa
    22981 aaacggacaa acctttggct taagcaaatc agaaggtgaa cacaaaatcg gtgaagcagt
    23041 tgaaggattc ggttaccaaa atcaaaaaca tgaaaatcgg atcactacac aaattcctaa
    23101 aagccgtatc ggtcattacg cttttggaat cgttactgct acacgaaaag atttaggtgc
    23161 gtttgtcgat atcggtcttc cagataaaga ctttgtcgta tctcttgatg aattgccgac
    23221 aatgacagag ctatggccta aaaaagggga tcgcttgatg atttccctta gagttgatgc
    23281 aaaagaccgt atttggggca gtttagcaga tgaaaaaata ttcaaatctt taagcaaata
    23341 tggaacagaa gaaatgaaaa acaaagatgt gataggaaca gcataccgct tgaaattaac
    23401 aggtacgtac gttttaacgg aagatttcta tcttgggttt atccatcctt ctgaacgata
    23461 taatgaacct cgtctaggcg agcagataaa aggtcgagtg attggtgtcc gaccagacgg
    23521 tgtactgaat ctttcattga agccaagagc atatgaagct atatcagatg atgcacaaat
    23581 gattttaacc attttagaac gttctgcaga tcagcaaatc aactttacag ataaatcgga
    23641 tccagaagaa atcatgaaag cttttggtat cagcaaagga gcatttaagc gcgcattagg
    23701 taatcttttg aaacaaggat tgattacaca agaaaacggt gtgacaaaac tagtcaaaaa
    23761 atctaattga gaatcccttg catgtttttc ttaactagct tataataatt ttaattaaca
    23821 tagtgttata tcttttttta tttgtaatta ttataaattg ttggggttga gtaaatggtc
    23881 atgaatgcta tttcggcgat gaaaaaaaca aaacagcagc tacatgaagc ggggtttaag
    23941 ctgacaccgc aaagagaagc tactctgctt gtgcttttgg aaaatgagaa agagcattta
    24001 tctgcagaag aaatcttctt tttagtgaaa aaaaagagtc cggaaattgg acttgctact
    24061 gtttatcgaa cccttgaaat cttgacagaa ttgaaaattg tcgataaagt aagttttaat
    24121 gatggattag cccgttatga tttgagaaaa gaaggcgcca aacatttcca tcatcattta
    24181 ctatgcttga actgcggcac gatcgaggaa gtagaagagg atcttttact tgaagtggag
    24241 caagtagtag aagaacgtta tcatttttta gtaaaagatc atcggctaac gttccatgga
    24301 atctgtcagg aatgctatga aaaa
//
LOCUS       DACBZK010000038        23801 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.039, whole genome shotgun sequence.
ACCESSION   DACBZK010000038 DACBZK010000000
VERSION     DACBZK010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23801
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.039"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..1248)
                     /locus_tag="IVD66_001616"
     CDS             complement(<1..1248)
                     /locus_tag="IVD66_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1476 family transposase"
                     /protein_id="HAP6145839.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQVILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMNSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTLEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYL"
     gene            1521..3992
                     /locus_tag="IVD66_001617"
     CDS             1521..3992
                     /locus_tag="IVD66_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP6145840.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(4095..5831)
                     /locus_tag="IVD66_001618"
     CDS             complement(4095..5831)
                     /locus_tag="IVD66_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HAP6145841.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(5828..6532)
                     /locus_tag="IVD66_001619"
     CDS             complement(5828..6532)
                     /locus_tag="IVD66_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6145842.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDLHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            6663..7166
                     /locus_tag="IVD66_001620"
     CDS             6663..7166
                     /locus_tag="IVD66_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HAP6145843.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            7126..7464
                     /locus_tag="IVD66_001621"
     CDS             7126..7464
                     /locus_tag="IVD66_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HAP6145844.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            7485..8903
                     /gene="ffh"
                     /locus_tag="IVD66_001622"
     CDS             7485..8903
                     /gene="ffh"
                     /locus_tag="IVD66_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HAP6145845.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            9015..9593
                     /locus_tag="IVD66_001623"
     CDS             9015..9593
                     /locus_tag="IVD66_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HAP6145846.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            9597..10118
                     /locus_tag="IVD66_001624"
     CDS             9597..10118
                     /locus_tag="IVD66_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP6145847.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(10197..10751)
                     /locus_tag="IVD66_001625"
     CDS             complement(10197..10751)
                     /locus_tag="IVD66_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP6145848.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            11004..11279
                     /gene="rpsP"
                     /locus_tag="IVD66_001626"
     CDS             11004..11279
                     /gene="rpsP"
                     /locus_tag="IVD66_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HAP6145849.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            11291..11542
                     /locus_tag="IVD66_001627"
     CDS             11291..11542
                     /locus_tag="IVD66_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAP6145850.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            11667..12458
                     /locus_tag="IVD66_001628"
     CDS             11667..12458
                     /locus_tag="IVD66_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145851.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            12628..13149
                     /gene="rimM"
                     /locus_tag="IVD66_001629"
     CDS             12628..13149
                     /gene="rimM"
                     /locus_tag="IVD66_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HAP6145852.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            13139..13900
                     /gene="trmD"
                     /locus_tag="IVD66_001630"
     CDS             13139..13900
                     /gene="trmD"
                     /locus_tag="IVD66_001630"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HAP6145853.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            14036..14383
                     /gene="rplS"
                     /locus_tag="IVD66_001631"
     CDS             14036..14383
                     /gene="rplS"
                     /locus_tag="IVD66_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HAP6145854.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            14756..15418
                     /locus_tag="IVD66_001632"
     CDS             14756..15418
                     /locus_tag="IVD66_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145855.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            15497..18724
                     /gene="fss3"
                     /locus_tag="IVD66_001633"
     CDS             15497..18724
                     /gene="fss3"
                     /locus_tag="IVD66_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAP6145856.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGHETQGKAEFKRAEYTL
                     FTVKDGKAVKWTENFKPELLKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDSEKNAVITRDVAAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            18838..19152
                     /locus_tag="IVD66_001634"
     CDS             18838..19152
                     /locus_tag="IVD66_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP6145857.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            19165..19539
                     /locus_tag="IVD66_001635"
     CDS             19165..19539
                     /locus_tag="IVD66_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP6145858.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            19549..19893
                     /locus_tag="IVD66_001636"
     CDS             19549..19893
                     /locus_tag="IVD66_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAP6145859.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            19964..21109
                     /locus_tag="IVD66_001637"
     CDS             19964..21109
                     /locus_tag="IVD66_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAP6145860.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQCATCF"
     gene            21824..23683
                     /gene="ltrA"
                     /locus_tag="IVD66_001638"
     CDS             21824..23683
                     /gene="ltrA"
                     /locus_tag="IVD66_001638"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP6145861.1"
                     /translation="MNKVKTNKTLRHSEYYGMTQIFDELYVKSDKKEVFTELMTIIMS
                     DENIRLAYRNIKNNKGSYTASTDKKSIRDIKTLSEDTFLTEVKVLFRCYKPRAVRRVE
                     IPKPNGKTRPLGIPSIWDRLIQQCILQVLEPICEAKFHNYSYGFRPNRSTHHAIATCN
                     RLANRGKLHFVVDVDIKGFFDNVNHSKLLRQMWTIGIRDKWLLGIIRSMLNAPIVLPT
                     GKVEHPKKGVPQGGVLSPLLSNIILNELDWWVASQWQNTTIETEKIMDRRDKGKGIDK
                     TNQYRALRRTNLKEIYIVRYADDFKIFCRKRSHADKIFHATKMWLKERLSLEISEEKS
                     KIVNLKKGKSEYLGFELKLIKKGKKYVVESHMSKKSMTRVKIQLKKQLRKVARPKNHC
                     EQAKEIGLYNSMVIGIHQYYGIATCVNLDCSKIAYTLKPFINHKLPTKKHGKILNTFI
                     KSKYGKSKEMRWLNNVPIVPLNYVQFRLAVPLSEGTCKYTESGRSKIHSKLKLDLALL
                     LHMMRNSNYERSIEFVDNRISKYSAQKGKCAITGKFLEYEEIHCHHIVPVKQQGTDKY
                     SNLIIIHKNVHALVHAIEEKIIHKYLNVLNLTNEQIEKLNELRVKAGNSVLTV"
BASE COUNT         8092 a         4210 c         4936 g         6563 t
ORIGIN      
        1 taaatagatc cgtgcccgaa agttataaaa gttgcgataa ccaaacgcaa ttcgtttaat
       61 cagcttgatc ttgttattca gcccctcagt gacgccgttt gagtgggaca ccttaaaggc
      121 atttgaaata cccgattggt agcgatggaa gatcgtgaat ttctttttaa acgactgagg
      181 taacgtagat gaaattgttt taagggtttc ttgaaagcct tccgtacctc gtttaacgaa
      241 ataatagcgt aataattgac aaaaatgata cgcagttcgc aattcttcgt tgtagcttaa
      301 cagctcatca acgatttctg tttgactaat tggtcgttta aacagtcgat gataatgccg
      361 tttgagtggc tccaatgtcg tggaatcttt gagtaagagt ttccaatatc gcttgagccg
      421 acggtacttc ttctgatttt cagagtgtga ggttcgaaaa cgattcatga tctggacacg
      481 taattgattg aagctgcgat tgatgtgttg gacaatatga aagcggtcag ttacgatctc
      541 cgcatttgga aagactgttt taagcaactg acaatagctg gcattcatgt ccatcactag
      601 gtacttgacc tttaaacggg cctttctagg aaagcgcagg aagtattgag ttagtttgta
      661 aagtctgcga tcttcaagga tcgtaaatag ctgattggtt gtcccatcaa cacaaataaa
      721 actcatggaa ccagaaacag aattcattga tttgaactca tccatacaca acaccgtcgg
      781 aaggaagttc atacgtggct ggtaatgctt cgttgcttca cgcaagatcc gtgtcaccgt
      841 cccatccgag acgaagtact tcttagcgat tagtttacgt gattgatttt cgtacagttc
      901 catgagaatc acctgcttca gttcctttgt tagttgatga tgttcatcaa ctaagtccgt
      961 tttcgcagaa aaggtccttc cacaatcatg gcagagaaaa cgggtacgtt ttaattctaa
     1021 aatagttaac ttttctttga ctttcaacat ctgagtgcgt gtcgtatagg aaccgttgcg
     1081 gataatacga accgatcgac agtgttcaca ataggaagaa gagtcatcca attttccttt
     1141 aataaactgc gcttgaacgc ctttatattc tttttcaatc agccattctt catcaaaaaa
     1201 taaatgttta tctgttaatc cgagtaattt tctagtatga ttatccattg agagactcct
     1261 ttggtaggat gacgttttgg tcgactaaat tttaccaaaa gtgagtctct ttttgagttg
     1321 aaacgaagaa aaagtgttag tagaaaatcg ccttcgattt tccaccaaca caaaatatta
     1381 tagaaccctt tttttttgct atatgacagg aatgaaaggt gtttgcaagc ttaatgtgag
     1441 gaacactttc catatctgtt ctatactgga taggagaagt ttggaaatat ccagaaaacg
     1501 aaatcaatcg aggtagccac atgaagaata aatggataaa tcgaagtaaa aaaaagaaag
     1561 taacacaaag atcatcagat aaagtcatcc gtctttttcc atcgtataaa gaaggattaa
     1621 cggcagatca agtcaaggaa cgaatagaaa aaggtgcagc aaataattca gtcgatccca
     1681 cattcaaaac aaatcagcaa atcgtattgg aaaacatatt tacgtatttc aatttgatct
     1741 ttcttatctt agccattttg ctttgtttag tagaatccta taagaacttg acttttttac
     1801 cagttatcat agccaataca ggaatcgcca tttttcagga aattcgatcc aaaaagatct
     1861 tggacgaact aaatgtttta aatacagcaa aagtcaatgt catacgagac gggatagaac
     1921 aaacaataga tatagaagac cttgtaatag atgacattgt tattttagag actggatatc
     1981 aaattccagc agatgcagag gtcgtggaag ggaaactgca agttaatgag gctttattga
     2041 caggcgaagc agatgaaata accaaagaaa taggtgatcc attaatgtcc ggcagtttca
     2101 ttgtttccgg aaaagcttac gcccgattag acaaagttgg agcagattcg tatatttccc
     2161 agctgacagt caaagccaag acaatgggag aaggagaaca gtcggagatg attgcttctc
     2221 ttaatcaatt gatcaaatgg attgggatca tcattattcc tatcggtatc ctgctttttt
     2281 ctcaaagtta cttttttaat ggaaacacga tcaaagaaag tgtcgttgca atggaagcag
     2341 cattgatcgg tatgatacct gaaggactgt acttgctgac gacgattgca ttagcattaa
     2401 gtgcgactaa actagcaaag caaagagttc ttttacacaa tatgaaaagc attgagacat
     2461 tggcaagggt aaatgtcctt tgtgtagata aaacaggaac gatcacagaa aataaaatgt
     2521 ctgttcaaaa aatgatcgtc tctaaaaaac aagaaataat cagtcagtca gatcaattgg
     2581 aagcatgcat tgctgactat gcaaaagcga tggcaggaga caatgcaaca atggaagctg
     2641 ttaaagcata ttttacaaaa accactgatc aatcctatca ccatgttatt cctttttctt
     2701 ctgtccaaaa attcagcagt gtagcgttgg cagacaaggt gtatgtttta ggagcgcccg
     2761 aaatggtttt gcgcgatcaa ttgccggaat atgcggaaga gtttgtttct ttcgctgaaa
     2821 aaggctatcg cgtgttggtc tttggtgtgt acgatgggat tcttgaagaa ccagtattga
     2881 cagaagcagt cacaccatta ggctatattc tgattgctaa tcctatcaga aaagaagcaa
     2941 gagccacatt tgattacttc aaaaaacagc aagtagccat caaagtgatt tctggagata
     3001 atccgctcac cgtatccaat gtagctgtcc aagcagggat ttcacatgct gatcagtacg
     3061 ttgatgcatc taaattatca gaagaagaat atgaagcagc tgtcgaaaaa tatacagttt
     3121 ttggacgcgt caagccagaa caaaagaaaa tcttcgttca attgataaag cgtaacaata
     3181 cagtagctat gacaggtgat ggcgtgaatg atattctagc catgaaagaa gcagactgca
     3241 gtatagcgat ggcttccgga aatgaagccg ccatgcaggc ctcacaagtg gtcttacttg
     3301 attctgactt ttcacgcatg ccagaagttg ttgcagaagg acggcgcgtt gtgaacaata
     3361 ttgagcgatc agccagcttg tttttagtga agaatatttt ctcctttttg ctctcactgt
     3421 tttcagtgat ctttgctctg acctatcctt tagaaccatc acaaatcaca ttgattagtt
     3481 tgtttactat cggacttcca tctttcttgc ttgctctaga agaaaacaaa aagcgaatca
     3541 gagggaaatt catcatgaat gtgatggaaa aagctgtgcc aggtggacta acagatatga
     3601 tcgtagtcgg tgcgttggtg atctgcgggg tgactttgaa tctaaataaa acagatgttt
     3661 ctacagcatc taccatgctt ttgattgcag tagggttcct cgttctctat aaaatctgtt
     3721 caccgctgaa taaattcaga agtcagatca ttcttttctg tgctagcggt aacttttttt
     3781 cggtcatctt tttgcataag ctgttttcaa tcaccggtat ctcagctgta tcacttttgc
     3841 tgttgagcat tctatttttc tcggcagatt cgatttttag gcatttgacc acattggtag
     3901 aatatttgtt tgaacgtaaa aatgaaaaag agcaaaagcc gtttagtcgc gtagctaaaa
     3961 aatttctatc gatatttaaa cgagaaaatt gacgaaaagt atctcaaaaa agagtaaaaa
     4021 agaacaacca ctcgtgtatc tttcgaagca ggatgagtca tccaacttta aaacgcacga
     4081 gcagttgctc ttttttacat tttcggaatg gtaacggtga aagtcgaacc tgttccaaga
     4141 tgactgtcta cagtaatcgt accattaagg agttgcacgt agtcttttac aatcgctaac
     4201 cctaatccgg tcccgcctga atgtcggctt cgcgccttgt ctacgcggta aaaacgctca
     4261 aagatccgtt cctgatcctc aatgtcgata cctataccaa agtcttggac agaaaacgat
     4321 agatcatctg ttgcctgata gcggataata atctcgctgt cgctttttga atattggaca
     4381 gcattttcaa ttagattttt gataattgga taaaggatat ctgttttagt agtaaatggt
     4441 tcgttctttc caatcaatcg aatcgtcaac cgtttctttt cgatgattgg ctgataattt
     4501 tgaacgattt gctggaaata aggttctgta taaattgtct ggatctcgta agaattctcg
     4561 ccatcttttg acagctggat gatttcccga atcagtttat ctaaccggat cgcatctttt
     4621 tgcatgatct caagaaaaga agtcagagtt tgcgggtcat cttttgcacc atccagtaaa
     4681 gtctcggtaa aaccaatcag tgaagtcaca ggagttttta attcgtgaga gacgttgcca
     4741 acgaaatcct tttgtagctt ttctaaacgt cgcactttcg ttaagtcata cgccacccct
     4801 agaatctgtc cggtaccttc tgaattagta aagtagcgca aactcaagtc taatgtctgc
     4861 cgaccttctg taagggtgat ctcctgatgg atcagcggat gctcaggagt cacttgatga
     4921 atcagctgaa tgagttttgg ctcttgaatg acttctgtgt accgctgttc aggttgatag
     4981 cttaccacgt ttaaatgtag ctgcatcttt ggattaagca gtagtaaacg agaatcagca
     5041 tcatcaatca ggaatacgcc aatcatcagt tcgttcagta acgtatataa ttgctcttct
     5101 gtggtagtac acgcccgata catcttactc atttgttcgc tcaacgcatt aatcgtctga
     5161 tacaattctt cccattgatc gggtgtttgc atgattactt ccgcctgatt aggattttgc
     5221 accatttttt ttagtacggg cagcacggtt ttcaatggct ggtttttttg atagatcaga
     5281 taatagatca ttcctgcaag aacaaggaag aaagacagaa agaagaaaaa gacccaacgg
     5341 cgaaaactct cagttctcgg taaaaaaccg cttgtcggtt ctgcgatacg taaaatggct
     5401 tctaactggc cacttttttt gactggtaat gcgacatata aaagatcctc attcaaagta
     5461 gtacttttgc gcaaagcgct acctaggttc ccaccattca atacggcttt gatttcggga
     5521 cgggagtttc gctgttcatt caatgtttca ttgtttgtgt caaataagat ctttccagta
     5581 gcatccatta aagtaatccg ttcgttcgac tgatggacga attcttccaa agcagttttg
     5641 ttttgcgctg cttggaggtt ttcgacatct aattgccgga tcagcagttg tgcttttttt
     5701 gtcaggtagc tttcttgctg ttccacgatc tgctgttgaa aataatggga aatcaattgc
     5761 cagccaccaa aaaacaaact aactaaaaga ataagaaaga agagacgttc ataaattttt
     5821 ttccatttca tcgtttgggt tcctgaaact tatagccaaa tcctctaata gtcaccaagt
     5881 actttgggtg ttttggatct cgctcgattt tttctcgcaa atgactaacg tgtaaatcta
     5941 cgattcggct ttgtcctgcg aagtcaaaat tccaaatgcg gtctagcaat gtgtctcggt
     6001 cgatcacacg gtcttttcgt ttcatgaaat aaacaagtaa ttcaaattct ttcggtgtta
     6061 gttcaatcag atggtcgtct acggtcactt gataattggt caaatcagca gtgatttgtc
     6121 caatcgatag atattcaggc tcagcttcat cttttgattg cttacgaggt tcaattcgtc
     6181 tgaatattgc tttcatacgg gctaatactt cgcgaggact aaatggtttg gtcaaatagt
     6241 cgtcagcacc tatttctagg ccaatgatcc gatccacttg gtcatcttta gccgtcagca
     6301 tcaaaatcgg tgtttcattt ttttcttgac gcagccgctg agtgatctcc atgccatcca
     6361 tcgttggaag catcacatct aaaatgatga aatcaaatga ttgttctaat gctaattcta
     6421 atccttcgcc tccatctgtg gcactggtta ccttgtagcc ttctttttcc aaattgaacg
     6481 tcaagagcgt tacaatagaa ggttcatcat caacaactag tatttttttc attcaaatct
     6541 cctttaaata ggtttcattc tgtttatatt ttagcataga atcagtacaa agggctattt
     6601 tacaaaagaa ataaatggta taataggaag gcactttgct gaatagaaag gaagagcagt
     6661 caatgattgg aatcagtgca tgtttaggcg gtctggcctg tcgctatgat ggacagaaaa
     6721 aagaagtacc agaattgatg gaactagttg aaactggaga agctgtcatg gtctgtccag
     6781 aagtgatcgg cggattacca attcctagag atcccgctga aatcattggt ggaaatggat
     6841 tcgatgtgtg gaaagatcaa gcaaaagtat ggacgacaag cggcgaagat gtaacggaag
     6901 cgtacaaaaa tggcgcgatc aaagcctatc aaaaattgca ggaaaaacac attgatctag
     6961 tcatcatgaa ggaaaaaagc ccttcatgcg gaacccattc gatttatgac ggaagttttt
     7021 ccggaataaa aaaaaatggt gccggagtgg ctactgctta ttttattcag caaaaaatga
     7081 ctgtgctctc tgatgaagaa tggctgaaaa ctagaggtga gcagaatgga aatcgaaaag
     7141 accaatcgaa tgaacgcgct ctttgaattt tattcgacct tattgacaga aaaacaaatg
     7201 aactacatgg aattatatta tgcagatgat ttttcattag gtgagatcgc ggaagaatac
     7261 gaagtaagcc gacaagcagt atatgacaat atcaagcgga caagcaagat cttggaggat
     7321 tatgaaaaaa aactccatct tttttctaat tatattgttc gagaacaggt attggaaaat
     7381 atgactgcat atattacaga taagtacccg gaagataaaa aactacttga atatgtacag
     7441 caaattcaag caatcgaaga ataaataaaa ggaatgaaga aaatatggca tttgaaagct
     7501 taactgaacg tctccagcag gcgatgggaa aaataagaaa aaaaggaaaa gtatcagaag
     7561 ctgacgtaaa agaaatgatg cgggaaatcc gccttgcctt actagaagcc gatgttaact
     7621 tgcaagtagt caaagatttt actaagcgcg tacgcgaacg tgcggtaggg gcagaagtgc
     7681 tggaaagttt atcacctgca caacaaatcg taaaaatcgt tgatgaagaa ttgacgatca
     7741 cacttggttc tgaaacagca gagttaaata aatcaccaaa aataccaact gttatcatga
     7801 tggctggtct tcaaggggca ggtaaaacga cctttactgg taaattagcc aattatttaa
     7861 agaaaaatga aaatgctcgt ccgctcctaa tcgcagggga cgtatatcga ccagctgcga
     7921 tcgaccaatt gaaagtatta ggtcaacagc tagacgttcc tgtatttgat atgggaactg
     7981 aagtcagccc ggtagagatc gtccgtcaag ggatggagtt agcaaaagaa aagaaaaacg
     8041 actatgtatt gatcgatacg gcaggacgtc tgcatatcga tgaaacattg atggatgagt
     8101 tgaaacaaat caaagaattg acgcaaccaa atgagatttt gcttgttgtc gatgccatga
     8161 ctggtcaaga tgccgtcaac gtagctgata gcttcaacca gcaattaggt attacagggg
     8221 tcgtcatcac taaacttgat ggggatactc gaggcggggc agcactatcg atccgctcag
     8281 tgacaggcgc accaatcaaa ttcatcggtt ctggtgaaaa attgactgac ttagaagtat
     8341 tccacccaga tcgtatggct agccgtatcc ttggtatggg ggatatgctg acattgattg
     8401 aaaaagcgca gcaagactac gacgagaaaa aagcggaaga acttgcacag aaaatgcggg
     8461 aaaattcatt cgatttcaat gactttattg aacagcttga tcaagtgatg ggtatgggcc
     8521 cactggaaga tctaatcaaa atgatcccag gaatgaatca agtccctgga atcgaaaacg
     8581 tcaaggtaga tccaaaagat gttgaacgca aaaaagcgat ggtttattct atgacgccag
     8641 cagaaagagc aaatcctgat ctgttgaacc caagccgtcg tcgccgaatt gctgccggtt
     8701 ctggaaacag tgttgttgaa gtgaatcgaa tgatcaaaca attcaaggaa tcaagaaaaa
     8761 tgatgcagca aatgtccaaa ggggatatga acatcccagg tatggaccaa atgtttggtt
     8821 caggcgtcaa aggaaaacta ggcaaaatgg cgatgaatcg aatgatcaag aaaaataaga
     8881 agaaaaagaa aaaacggaaa taagatgaaa aaaacagctt cggtacagac tgaaaatgtc
     8941 tactgccgga gcttttctat cagcaatttt tattctttac taatacaatt actctaaacg
     9001 aagaggtggc acagatgaga tgtccgtgga gtgaacaaac agaaagtatg cggcaatatc
     9061 atgatactgt ctggggtgtt cctgaatatg atgaccaaaa gctgttccga aaattgatgc
     9121 ttgatattaa tcaagccgga ttgagctggc agacgatttt aaataaaagt gaagcattcg
     9181 atgaagcata tgatcgattc gatatcaaaa aagtcgcaaa ttatggagaa acaaaaatca
     9241 gtgaactaat ggaaaacaaa ggaattattc gtaaccgaag aaaaatcgaa gcagccgtcc
     9301 aaaacgccaa agcagtcttg aaaattcaag aagaaatcgg cagtttttca gagtatcttt
     9361 ggtcgttttc taatggaaaa atcgttgatt cttcttatca ttcacaagaa gaagtcccaa
     9421 caacaagtcc tctttcagat gaattagcaa aagatctaaa gaaaagagga tttaaattta
     9481 tcggaagcac aacaatctat gcttttttag aagctgtcgg gatcatcaat gatcaccttg
     9541 acagttgttt ccgcaaagaa gaggtcgtac gtatcggcag aaagggcgaa taaagcatgc
     9601 gaaaaatcat attttatggt gctataagtt tagatggcta tttggcaacg aaaacggatg
     9661 atcttcaatg gctttttgac actccaacag gtaagcaaac tacttatgaa gctttttatg
     9721 aaacaatcga tacgaccatc atgggcagaa aaacttatca ggaagcaaaa aaatatttgg
     9781 agaccgaagc aatttatcca gagaaaaaga atttcgtttt ttccacccac gcacaattac
     9841 aattgccaga tgctgaggtc gtaaacgaag atcctgttgc ttttctaaaa aatctacaaa
     9901 tgacagaagg aaaagatatc tgggttgtgg gtggcggtcg attgatcaaa ccgctattgg
     9961 aacatcaaat gattgatgaa tggtatatcc agattacccc tgtattatta ggggacggga
    10021 ttcctttatt ccaaaaagga acatatgaag cgcgttttga aatgctagac acgacacgat
    10081 tcggtgaatt tatcgaattg cattatgtac gaaagtagaa gtaaataaaa taaaaaaggc
    10141 aactatatgc agaaatgtcc tgtacatagt tgcctttttt attaccgtta tgctttttac
    10201 tctgttaatt tgttagaaaa atctagatac gcatctaaaa tcgtttggaa gaaacttaat
    10261 gttccttcaa cgatattacc attttcatca attagattcg caacgtttcc gatatatgct
    10321 tccggttgct gcaaggttgg cacattcaaa aagacaagtg attggcgtag atggtggttt
    10381 gcgccaaagc cgccgatccc acctggtgat gcagtaacga ctaaacctgg tttatgatcc
    10441 caaacactgt gtccataagg tcttgagcct acatctaaag catttttcaa tactgctggc
    10501 acagaacggt tgtattcagg agtaacgaaa acgacaccgt ctagtcccct cacttcctca
    10561 cgaaaacgag tccattcagc aggagcctgt tctggagttt cgagatcctc attgtaaaat
    10621 ggcagatcat cgatttttac aaatacactt tcgtaccctt caggaagcaa tttcgcaaaa
    10681 gcttctgcta cttttttgtt gtaagaatct tttcttaaac taccaataaa aaatccaatt
    10741 ttttttgtca tacgattttt cctccttcaa actatctata ataatcttac aaaagataag
    10801 taactggagc aaataaaaac acttactgac aaaagctaca tagaagatag attacttatt
    10861 tttaacaaaa aagaagtcta aaatcttcta ttttctaaaa aaaatcgaat ttaatcaagc
    10921 tgtaaagaaa aaaagcttta cagggtaaaa aaaaactgtt acactacatc ttgtgaataa
    10981 aacaatggag gtggaaataa ataatggcag ttaaaatccg tttaaaacgt atgggttcta
    11041 aaaagagtcc gttttaccgt atcgtcgtag ctgattcacg ttctcctcgt gatggacgtt
    11101 tcatcgaaac tgtaggtact tacaatcctt tgaaagaccc tgcagaagta gttttaaaag
    11161 aagacttagt tcttgactgg ttatcaaaag gtgcacaacc ttctgacact gtacgtaaca
    11221 tcctttcaaa agaaggcgtt atgcaaaaac accacgaagc taaattctca aagaaataag
    11281 gtgaccggat atgaaagatt taagcgactt agtcttaaca atcgttcgtc cgctagtcac
    11341 ttatcctgat caagtcaagt tagacgtcgt agagtcgaaa gacttttacg agtacaatct
    11401 aacagtggct cctgaagata ttggccgtat cattggaaaa caagggcgtg ttgctaaagc
    11461 aatccgcaca atcgtttacg gtgttcggat caatgcaccg aaaaaagtgc gtttgaatat
    11521 catcgatgat aaggaaaagt aaataaacgt gctgtactcg aattttcgag tgcagctttt
    11581 ttgttttttt tattaattga agaaatgatt atttggcaaa acaagcaaga aagcgtatcc
    11641 ttataggagg agggagtgaa cagccaatga gaaagaaaat gttatttatt ccatttgctc
    11701 tattgttaag cgcttgtagt tcggttactc aagaatcaga caatacacat ctatcaagca
    11761 gtatatctga aactgttacc agtccagaaa aaagtagtac caaaacggct tccaccactg
    11821 aacaaacaat ggctacctca aataatgaga aaaagactgc tttagaccag ttgaaagaac
    11881 aacagccaaa tgttcccatg cctctagatg taccagtctc ttcaggctat ctcaatatcg
    11941 cagcgacaca tacaaagcaa ggttattcta ttttatatta cagaacagat cgtcccctcg
    12001 ggttgaatgc tgacgaattg aatcaagaaa cgcctattgc aacctatcta tatcaatatg
    12061 ggtttgcttc tagtcaagaa acaatccaag ttttgcagcc atttgagatc gacacaaatg
    12121 gtcagcaagt ggacttaggt tctcgaatca cagggtatca gcaaggtgca gcaggttcaa
    12181 gttttcttga atggcaagaa ggaaactggc gtattcgaat ccgtgggaat aatatagaag
    12241 gccaagatcc cttactatta gctaaagaaa tcgtagctta tttggaagaa aacagtctac
    12301 cagcacctga acaatttggt aaaattactg ttgatatggg tgatacgacg aatcgagccg
    12361 tagaagtaag ctggcaagaa ccgaaaaatg cctatacgat cactcatcaa gatcctatgt
    12421 ctgcgttgaa gatggcagtt tctatgaaga ggttgtgaaa tcagcgcgct gatctgagcc
    12481 catcatttaa ctccaagtca caggaagtaa tcaaaaatag cacgccgcat ttttgcataa
    12541 ttttggctta ataccttaaa agaaaactag aattgcctct tcacacatgc taaaataaaa
    12601 cagacaaaaa agaaatgggg atataagttg actgaatact tgaatgtagg aaaaatcgta
    12661 aacacacaag gtatcaaagg cgaagtccgt gttatctcaa caacggattt cccagaagaa
    12721 cgttacaaaa aaggaacggt gctaacacta ttccaagacg gaaaagcacc tgtggaatta
    12781 acagtcaaaa gtcatcgcaa acataaaaat tttgacttat tgagttttga aggacatcct
    12841 tctatcaatg atgtggaaaa atatcgggat ggcatattaa aagtgtcaaa agacaactct
    12901 gtagatctag ctgaaaatga attctattac catgagatca tcggtctgca tgtattagaa
    12961 gatggaactg agttaggtaa agtaaaagaa atcttgtcac caggtgccaa tgatgtttgg
    13021 gtcgttcaac gtccgaaaaa agctgatata ttgcttccat atatcgcttc tgtcgtcaaa
    13081 gaagtcgatt tagaagctgg agtggtccgt gtagaaattc cagaaggact gattgacgat
    13141 gaagattgat gtattgactt tatttccaag aatgtttgaa ggtcctatgg gggaatccat
    13201 catcggtaag gctgtagata aaggattatt agatatcaat atctctaact tccgcgatta
    13261 ttcagataac aaacatcaga cagtagatga ttatccatac ggcggtggag caggtatgct
    13321 gctcaaagtc cagcccatct atgataacat ccaagccatt gaaaaagctg caccggatgt
    13381 caaaaaaaga gtaattcttc ttgacccagc tggtaaacga ttcgatcaga aaatggcaga
    13441 agaattttca caagaagaac acttagtatt catttgtggt cattatgagg gatatgatga
    13501 acgtatccgc acattagtga cagatgaagt ttccttagga gattatgtcc ttactggggg
    13561 agaattaggt gcgatggtca tgatcgatgc aacagttcgg cttttgccag atgtgttagg
    13621 gaatcagact tcagctcaaa cggattctta ttcaaccggt ttattggaac atccccaata
    13681 tactcgcccg gcagaatata aagggatgaa agtaccagaa gtattgacaa atggaaatca
    13741 taaattgatt gaagaatggc aattaaaaga atcactaaga aggacctatc aacgtcggcc
    13801 tgatcttttg gaaacacttg aatggacacc tcaaatgacg aaatttttag aagaaatcaa
    13861 gaaagaagaa caagaaaaaa cagcagatga agccaagtga ctttttctaa aatcttcttt
    13921 acagtaggtt gataatatgt tagtatttta tggtgagtgc aaaagcactt aactattacg
    13981 atattccgct gtgagaaaag ctcataagaa tatttggaat aaggagaaga aaaccatgaa
    14041 tccattaatc gaagaattaa caaaagaaca attacgttct gacatcccag cgttccgccc
    14101 tggtgacact gtgcgtgttc acgcaaaagt tgttgaaggt actcgtgaac gtatccagtt
    14161 atttgaaggt gttgttatca aacgccgcgg tgctggaatc agcgaaactt atacagtacg
    14221 taaagtttct aacggagtgg gcgttgaacg tacattccca ttgcatacac cacgtgttgc
    14281 aaaaatcgaa gtagttcgct acggtaaagt acgtcgtgca aaattgtact acctacgtgc
    14341 attacacgga aaagctgctc gtatcaaaga aatcagaaga taaacacgga aaacttcctt
    14401 ggaaatctga aatttgtgaa aagtccttgt atatcaaggg ctttttcttt tttctctatc
    14461 acagttttaa gccatttttg gctgttttgg accatttttc aatcatattc ccttaaaaat
    14521 tgtcctagat tgtccgacat tgactatcag tgtcgtcaaa atagggcaaa atttagtagt
    14581 cagcttgacg acaaatataa tacgaaaaat accaaaacat ttaccgaatt tagcaacttt
    14641 tgaacccaag tttctcaaag ggtcagctat tagcaaaaaa gacaaaacat gtacttttct
    14701 actaaaaagt tgatgtgata ggcttctatc taaataacta ttaggagttt ttatcgtgaa
    14761 gcaaaatgat ggacgtatca tttggaaaaa tcaaagtgag ttaaaactga ttttaacaat
    14821 taatgaattc atcgaaaaac acggaattac atctagccgt caataccaga aaaagctatc
    14881 agaaaatcca aattctgcac caagtatgtg gttcattaac aaaaaatatg gatcatggga
    14941 gaatttattg attagtatag gacgagaaaa tactgggtat ggaaaatggg ctagaatgtc
    15001 agaacaagaa ttattggaaa tagtagaagc ctttattaag tgcgagaaga taacctctca
    15061 acgaatgtac gaacaaaaat cagtagggaa gaatattcct tcacttagta ccattaaaaa
    15121 gatgttagga gatatacgtc cactttttaa agaaaaaaat gatggatctc gatttactga
    15181 tttcgaactg ctgttagaac taaaaaatga aataatccga ttaaaactac aggatgattt
    15241 atcaatgaca aagtttcgaa aactagttca atccccaaaa ctaccatcag ttgatacaat
    15301 tatgaaaaga acgaacaaaa attgggagga attgatggca gagattggat ttgattatcg
    15361 aagaatcaaa atttataagc agagaaacaa cctatccaag acaaagaaaa ctaaatagta
    15421 tcactctaaa tcagacgttc aaaattaaaa tttggacgtc ttttttatta cccaaaaacg
    15481 aaaggagatt tattttatga aaaagccaag atttaagaat tggcgtttgc tcgcaacact
    15541 gagtctatta tgccaaacaa ttggtggatc gcttggccca acgattgcct ttgctgatga
    15601 aattactcat ccacaaacgg taactgtgga attggatttg gctcaccagt atgctgtcga
    15661 aggtacattt agcgatggtc gtcccatgtc agaagttacc gttccgcact atgcagttta
    15721 caatggtgtg aagcaagata ttttctgtat tgagccaggg gtgccgattt acaatgagtt
    15781 cactcctggt tatgagaaaa atccattgcc tgatatgtcg gagaaagcga aattagtttc
    15841 cgttttatgg aaggaagctg gtacggatgt ggatacacat attgtggccc agaagatgat
    15901 ttggcaagaa gttaatggct acacgcttca ctcaattaaa cgttctgatg gtagtgcagt
    15961 aaatatcgca gccattgagt caaaaatcaa tcaagccatt gcggattatc aaaagaaacc
    16021 aagcttccat aactccacag tgaaaaccgt gttaggtcaa tcgactactg tgacagatac
    16081 gaacggcttg aatttatcgg agtttgatga agttgtcgag aatatcgcaa atattgatta
    16141 tcgtgtgaac ggcaatcaac tagtgattac tccaaatgcc aattcaaaag agagtggtga
    16201 attaacccta aagaagtcag ctaatacagg aacaccggta gcttataaaa tggctggtca
    16261 acaaactttg atggcggggg caattgataa gcccaatacc tacacaatca aaattgatgt
    16321 ggaaactgag ggttctttga agattaaaaa agtcgataaa gaaacaggaa atgttgtacc
    16381 gggaaccgtt ttccatttag actttggaaa aacattacct gcaaaagacg tgaccaccga
    16441 taaagaaggc attgcgacat tggatgagat tcctcatggc gcgaaagtaa ccattactga
    16501 aaaatcagtg ccagctcctt atacgattga cactacacca atcaccgcaa ccattaaatc
    16561 tggtgagact atttctgtga cttcaaaaaa tactcgcgaa aaaggtcaaa tcattttgaa
    16621 taaaatgggg gtggaaacag gaactgatct ttggaacgac aaatactcat tagccggaaa
    16681 tacgtttgcc attcgcaaag acagtccaac cggtgaaatt gtccaagaaa tgaccacgga
    16741 tgaaaaaggt catgcggaaa caccaaaaga gattgccaat gcgttggaat tgggaaccta
    16801 ttatgtgacc gaaaccaaag ctagtaatgg ctttgtgaat acctttaaac cagtaaaagt
    16861 cgaattgaat tatgtcaatc aaaccgtggc tcttgttacc agtaacgtaa aagggcaaaa
    16921 ccaagaaatt actggtgaaa ccactttgac aaaagaagac aaagataccg gtcatgaaac
    16981 tcaagggaaa gctgagttta aaagagctga atacaccttg tttactgtta aggatggaaa
    17041 agcggtcaaa tggaccgaga actttaaacc agaattgttg aagggaacga aagcttctga
    17101 tgaaaccgta actttgactt tagatgaaaa gaatcaagtt gccgttaaac acttagcgat
    17161 taatgagtat tactggcaag aaaccaaagc gcctgaagga tataccttgg atgaaacaaa
    17221 gtatcctgta tccatcaaaa aggtggatga tagcgaaaaa aatgctgtga ttactcgaga
    17281 tgttgcggca aaagaacaag tgattcgctt tggctttgat ttctttaaat ttgctggatc
    17341 agctgctggg actgccgaaa ctggcttcaa tgatctgacc tttaaagtat cgccattgga
    17401 aggaaccagt gagattacag gtgccgaaga tgaagcaatt acagcttata acgagcaact
    17461 aggttttgat ggctatggca agtttgaaaa tcttccttat ggggattatt tacttgaaga
    17521 agtagaggct ccagaaggat ttcaaaaaat tacgccatta gaaatccgtt ctacttttaa
    17581 agaaaataaa gcggattaca ctaagagtga atacattttt acgattaccg aaaaaggaca
    17641 aaaacaacca attaaaacgg tgaccgttcc ttacgagaaa ctgacgaata aagcattttc
    17701 tgttagcttg aatcgtttga tgctctatga tttacctgaa gaagaagata gcttaacttc
    17761 tcttgggact tggaaagacg gaggcaaaga attgacagac cttgattcta ccgagctagt
    17821 tgataaattg agctataact tgcatgaaat caaagaagac tggtatgtgg tagcgcaagc
    17881 cattgatgtg gaagcgacaa aagctgccca agaaaaagat gaaaaagcca aaccagtggt
    17941 aattgccgaa acaaccgcaa cgttggcgaa taaagagaaa acaggaactt ggaaaatttt
    18001 gcataaatta accgcagaac aagttttgga taaaaccatc gtcttattca actatgtgta
    18061 tgaaaacaag aaaccctatg aagcaggtga tgatccagta gcgaaagatg ctagcttgaa
    18121 caatcaagcc caaactgtca attgtacggt ggaacgccat gtttccatcc aaacaaaagc
    18181 ccacctagaa gatggttcgc aaacctttac tcatggggat gtggtggata tgttcgatga
    18241 tgtgtcgatt actcatgatg tactggatgg ctcaaaagaa gcttttgaaa caattctgta
    18301 tgcattactt ccggataata cgaccaaaga aatttggaaa tctggcaaaa ttgattatga
    18361 agtgaatgac aaagaattca ctaaaaccgt acttgcggaa aaagtggaca caagtaaata
    18421 tccagaaggt acaagtttta ccttcaaaga aattaactat ggcaaagacg gaaacatcaa
    18481 tgggaaacac aatgaggatc taaaagaaaa aactcaaact ttaacaccta aaaaagttcc
    18541 gacaacacca agtgcaccag aacaaccgga aataccaact gttccaagtg actctcaaga
    18601 atctagtcct acagtaaaga cattcccaca aacaggggag aaaaattcta atgttctgct
    18661 gtttattggg tttaccttga tctttgcgac tgctgggtat tatttctgga atcgccgaaa
    18721 ctaaggtgat gtgatgaaac aactaaatag gaaaaaccaa cgtgcgcgac cgcctcctaa
    18781 aaaaagtggt cgcgctattt ttgtatccaa aactaaaaat gaaaagagga aaagaagatg
    18841 gaattgaaat ttgttgtgcc agatatggcc gaaacctttg gaaagataag gtatgccggc
    18901 gaaggcgaag ttttaactga aggatatggg cggaatacta cagtaattgg tcgtagttat
    18961 catttgtatt ccagtaagca acgagccgat gatattgaag tggtggtagc tgcggaagcc
    19021 ggcgaaaagg attttgatca agatcaacca ctaaaagccg tgaatcccca tttggttgcc
    19081 aaaggctatg agattgagaa tcgtgggttt accgactacg tgttgtatgt cgatgattta
    19141 gtgaaagcat aggaggaaaa gaagatgaga ttaacagaag gtattgttgt agattcagga
    19201 ctaacgtttg ggaaattacg attttccgca ttacgccgag aagtacggaa gcaaaatgag
    19261 gatggaacgg ttagtaacga ggtaaaagaa cggacttata atttgaaatc ctctgcgcaa
    19321 ggtcgaatga tccaagttag tatcccagca aatgtaccct tacgcgagtt tgcctatgac
    19381 gcagaggtag agttggtcaa tccaatcatg gatacggtcg ccaattatgt tttccgagaa
    19441 ggaactactg tcaattggtt cattaaggcc gatgatttag tcttgaaacg acaaccagat
    19501 cagggaaatt ctacaaacca aaatgaagga aagaaatagg tgaagcgtat ggaaattaat
    19561 gttgaacata ttttagattg tctcgatcaa tatggaaaag gtgagctaac ggaggaacaa
    19621 ctcactaaag cattaaccta tgatgaaaaa atgtttctga ttatgcatca agggttactg
    19681 gaagtaggta acgatgccga agaagatttt gatgtactga attggttagg ggaagaagag
    19741 tccttcttta tggttatcga agtaaatgaa agtctatgtc gagaagccga aaccgtattg
    19801 gaagaaattg gtgtggaaat gccggatgcc attgaagttt ttttaaagca actagtggaa
    19861 acgaaacaac tccctatagc agtaaatgac tagcataact gcttgaaatt ggatcaatga
    19921 aatcctatga agcttttttc gattggaggt ggaaaccata aaaatgtaca aagggcatcg
    19981 tatacgggca ggagatcagc acttggttta tcactttgtt cttggctggc tactcgctct
    20041 gttcatcggt tggatgagcg tcttttattt tcaagagctt agacaatttg atatttctaa
    20101 gctatcactt tctactatag aaatcgttcg ttctataaaa gatttaatct atttgctagg
    20161 aagtctcgtt ctttcaggaa gcacgatgtt gctttatata cacttttttc aggatcattg
    20221 gcgcagtttg tggcatcgac aaaagctagc ccggatgatt ctagaaaatc attggtacga
    20281 agtaaaacaa actcagagtg aaggattttt caaagacctc aatagtagtc gaaccaaaga
    20341 gacaatcagt tacttcccca aaatctatta ccgtatgaag gatggtttac tttctattcg
    20401 cgttcaaatt tcactgggaa aatatcaaga tcagctttta aagctggaaa agaagttaga
    20461 aagtggtcta tattgtgaac tagtagaaaa ggaactcaaa gactcctatg tggagtacac
    20521 tttactgtat gatataattg ccaatcgaat tgggatagac gaagtagtgg cagaaagtgg
    20581 ggctttgcga ttgatgaaaa atcaagtatg ggcttatgat tctttacctc atatgttaat
    20641 cgctggcggc acaggtggtg ggaagactta ctttttactc actatcatcg aggctttatt
    20701 aaaatctgat gccgagcttt ttgttcttga tcccaaaaat gcggacttag ccgatttagg
    20761 tacggtaatg cctcatgtct attcccaaaa ggaggaaatt tctgcttgtg tggaagattt
    20821 ctatgagcgc atgatgactc gtagcaaggc aatgaaagaa atgcccaact acaaaacagg
    20881 agagaattat gcgtttcttg gacttccacc aaacttttta atctttgatg aatacgtggt
    20941 ttatatggaa atgttaacga cgaaggaaag tgcggtgatt ttgaataagc tcaaacaaat
    21001 cgtgatgtta ggtcgtcaat ctggtttctt tctgattcta gcttgtcaaa gaccggatgc
    21061 gaaatattta ggagacggga ttcgcgatca atgtgcgaca tgtttctaac tgaaaaggtt
    21121 aggcacttaa aagaagaaaa cataagtttc cttttaagga gaactgatat tttgagcagt
    21181 ggaatgatgg ggtaacgccc tgaaacgctc ccttaatact ccgactggct gtttaacata
    21241 tagctgttag atggtcagaa gctcggtgaa gtcggctgaa agttaccgta aatatgataa
    21301 attcatatac gaaagttgtt cagaggtgaa tgatgtaacc tataggtcgg aggtctataa
    21361 aatactcacg gtgagaatgt aagtaatact actgacgaac ttgcgaatga aagaatctat
    21421 acacggactg tatagaaatg tacaggattc taccgtatca acggaacaga atgtatgttg
    21481 tggtttagta agattattgg ttatgaacaa ccatgcaatg ttacaggcat tggaaatata
    21541 caggttcaaa gcaagcacct aaaagtatat ataaagataa aaatatcgaa acatgggaag
    21601 ctggcaatgt ggaggaaact atattccatt gaaacatttg tgacgaagaa taataagcac
    21661 atttatgcca gtgaaagtgg tggcacagta ccaatgagga tatagaaata tatcggagga
    21721 atagccacta gtcaaaagaa atcgttaatt aaatgatgta tttcatagaa tcgagtaaga
    21781 caaaataaac actacaacct aagtaaacaa aggtagtggt gctatgaata aagtaaaaac
    21841 aaataaaaca cttcgtcata gtgaatacta tggcatgaca caaatatttg atgaactgta
    21901 tgtaaaaagt gataaaaaag aagtttttac agagctcatg acaattatta tgagtgatga
    21961 aaatattcga ctagcataca gaaatatcaa gaataacaag ggcagttata cagcgagtac
    22021 cgataagaaa agtattcgag acattaaaac actgtcagaa gatacctttc taactgaggt
    22081 taaagttctt tttcgctgtt acaaaccacg agcagttaga cgtgtagaaa ttcccaaacc
    22141 aaatggaaaa acacgccctc tgggcattcc atcaatctgg gataggttaa tacaacagtg
    22201 tattttacaa gtcttagaac cgatatgcga agctaaattt cacaattata gttatggatt
    22261 tcgaccaaac cgttccacac atcatgcgat tgctacctgc aatcgactgg caaatagggg
    22321 gaagctacac tttgtagtag atgttgatat taaaggattc tttgataatg tcaatcactc
    22381 taaacttttg cgtcaaatgt ggacgattgg aatccgtgat aaatggctat taggtattat
    22441 tcgatccatg ctaaatgctc ctatagtcct accaaccggt aaagtcgaac accctaaaaa
    22501 aggtgtacct caaggtggtg tcctatcccc tttactatct aatatcatat tgaatgaatt
    22561 agattggtgg gttgcttcac aatggcaaaa taccacgatt gagacagaaa agattatgga
    22621 taggcgagat aaaggcaaag gcattgataa gactaatcag tatcgggcat taagacgaac
    22681 aaacttaaaa gaaatataca ttgttcggta tgctgacgac ttcaaaatct tttgtagaaa
    22741 acgaagtcat gcagataaaa tatttcacgc aacgaaaatg tggcttaaag aacggttatc
    22801 acttgaaatt agcgaagaaa aatccaaaat tgtcaatctc aaaaaaggta aatcagaata
    22861 tctaggattt gaattaaagc taatcaagaa aggtaaaaaa tacgtagtcg aaagtcatat
    22921 gagcaaaaaa tcaatgacaa gagttaaaat ccaattaaag aaacaattac gtaaagttgc
    22981 cagaccgaag aatcattgcg aacaagcaaa agaaattgga ttatataatt ctatggtgat
    23041 tggaatccat caatattatg gaattgcaac ctgtgtaaat ctcgattgca gtaaaatagc
    23101 ctatacacta aaaccgttca tcaatcacaa actgccgaca aagaaacatg gaaagatatt
    23161 aaatacattt atcaaatcga agtatggaaa aagtaaagaa atgcgatggt tgaataatgt
    23221 gccaattgta ccgctcaact atgttcagtt tagacttgct gtccccctat cagagggaac
    23281 ttgcaagtac actgaaagtg gacgaagcaa gatacacagt aaattaaaat tagacctagc
    23341 ccttttactt cacatgatga gaaatagtaa ttatgaaaga agtattgaat ttgtggataa
    23401 cagaatatct aaatattctg ctcaaaaggg aaaatgtgct atcacgggta aatttctcga
    23461 atacgaagaa atccattgcc accatatcgt accagtaaaa caacagggta cagacaaata
    23521 cagcaacctc attattattc acaaaaatgt tcacgcatta gtccatgcta tcgaagaaaa
    23581 aatcatacac aaatacctga atgtattaaa tctaaccaat gaacaaatag aaaaactaaa
    23641 tgaattacgt gtcaaagctg gtaatagtgt tttaacagtt taacttgaaa aatatatcat
    23701 acttaacatt cttttgatgg aacgccgtat gaagtgaaag tttcatgtac ggtgtgaagc
    23761 gggggaaaat ctggagatga catcaaagga ttacctatcg c
//
LOCUS       DACBZK010000039        23578 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.040, whole genome shotgun sequence.
ACCESSION   DACBZK010000039 DACBZK010000000
VERSION     DACBZK010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.040"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            44..676
                     /locus_tag="IVD66_001639"
     CDS             44..676
                     /locus_tag="IVD66_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAP6145862.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(678..1583)
                     /locus_tag="IVD66_001640"
     CDS             complement(678..1583)
                     /locus_tag="IVD66_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAP6145863.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(1668..2321)
                     /locus_tag="IVD66_001641"
     CDS             complement(1668..2321)
                     /locus_tag="IVD66_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAP6145864.1"
                     /translation="MIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFYAN
                     PEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEVRV
                     YDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYDYY
                     KELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVAI"
     gene            2643..3587
                     /gene="mvk"
                     /locus_tag="IVD66_001642"
     CDS             2643..3587
                     /gene="mvk"
                     /locus_tag="IVD66_001642"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HAP6145865.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            3580..4557
                     /gene="mvaD"
                     /locus_tag="IVD66_001643"
     CDS             3580..4557
                     /gene="mvaD"
                     /locus_tag="IVD66_001643"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HAP6145866.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            4570..5655
                     /locus_tag="IVD66_001644"
     CDS             4570..5655
                     /locus_tag="IVD66_001644"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HAP6145867.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            5652..6716
                     /locus_tag="IVD66_001645"
     CDS             5652..6716
                     /locus_tag="IVD66_001645"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HAP6145868.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(6965..7768)
                     /locus_tag="IVD66_001646"
     CDS             complement(6965..7768)
                     /locus_tag="IVD66_001646"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HAP6145869.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(7788..8630)
                     /gene="kduI"
                     /locus_tag="IVD66_001647"
     CDS             complement(7788..8630)
                     /gene="kduI"
                     /locus_tag="IVD66_001647"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HAP6145870.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(8646..9653)
                     /locus_tag="IVD66_001648"
     CDS             complement(8646..9653)
                     /locus_tag="IVD66_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAP6145871.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(9660..10304)
                     /locus_tag="IVD66_001649"
     CDS             complement(9660..10304)
                     /locus_tag="IVD66_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAP6145872.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(10404..11162)
                     /locus_tag="IVD66_001650"
     CDS             complement(10404..11162)
                     /locus_tag="IVD66_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HAP6145873.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(11289..12440)
                     /gene="fucO"
                     /locus_tag="IVD66_001651"
     CDS             complement(11289..12440)
                     /gene="fucO"
                     /locus_tag="IVD66_001651"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HAP6145874.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(12522..12833)
                     /gene="rhaM"
                     /locus_tag="IVD66_001652"
     CDS             complement(12522..12833)
                     /gene="rhaM"
                     /locus_tag="IVD66_001652"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HAP6145875.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(12835..13680)
                     /gene="rhaD"
                     /locus_tag="IVD66_001653"
     CDS             complement(12835..13680)
                     /gene="rhaD"
                     /locus_tag="IVD66_001653"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HAP6145876.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(13694..14950)
                     /gene="rhaA"
                     /locus_tag="IVD66_001654"
     CDS             complement(13694..14950)
                     /gene="rhaA"
                     /locus_tag="IVD66_001654"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HAP6145877.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(14947..16407)
                     /gene="rhaB"
                     /locus_tag="IVD66_001655"
     CDS             complement(14947..16407)
                     /gene="rhaB"
                     /locus_tag="IVD66_001655"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HAP6145878.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            16560..17429
                     /locus_tag="IVD66_001656"
     CDS             16560..17429
                     /locus_tag="IVD66_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP6145879.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(17555..18454)
                     /locus_tag="IVD66_001657"
     CDS             complement(17555..18454)
                     /locus_tag="IVD66_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP6145880.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(18619..19443)
                     /locus_tag="IVD66_001658"
     CDS             complement(18619..19443)
                     /locus_tag="IVD66_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP6145881.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(19454..20749)
                     /locus_tag="IVD66_001659"
     CDS             complement(19454..20749)
                     /locus_tag="IVD66_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HAP6145882.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(20765..21244)
                     /locus_tag="IVD66_001660"
     CDS             complement(20765..21244)
                     /locus_tag="IVD66_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HAP6145883.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(21250..22278)
                     /locus_tag="IVD66_001661"
     CDS             complement(21250..22278)
                     /locus_tag="IVD66_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HAP6145884.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(22295..23401)
                     /locus_tag="IVD66_001662"
     CDS             complement(22295..23401)
                     /locus_tag="IVD66_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAP6145885.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
BASE COUNT         6779 a         5200 c         4239 g         7360 t
ORIGIN      
        1 tcccgcttct ttgctatact aaagaaaaac gaggtgaacc cacatgaaaa aaatcgaacc
       61 tattccacct tctcttcctc ttcttacaaa gggagagttt tatttagaag atgaggagat
      121 cttctctggt cttctgatca acgggggtga ccaaagctat ctcgatgcca aaaatatggt
      181 attaagagag agtcatatcc aaaaacttac gatgcaaaaa acagttttac gtcattttga
      241 atgcagtaat gtcatttttg aaaaatgtga tttttccaat ctggagtgga ttggtggcag
      301 tttccaccaa gtcgtgtttc atcaatgtaa attaacaggt acgaattttg ccgaaagtta
      361 tcttcgagac tgtactttca ctgattgtat tgcttcgatg gcttccttta gtagtacaaa
      421 cttgaaagct gtctccttcg atcattgtca attagaagac agcgaatttt atgaggtcac
      481 ttggaaaaac ctttttttgt ctgacaatca gttgaccggt tcgaactggt ttcgaacttc
      541 tctgaaggga ttagacttta cgactaattt cttcacagca atcgctttat ctcaagattc
      601 tttggcggga ctaatcgtca accaagagca agcacttgtg atcgcccaag cccttggttt
      661 gcagatcaaa gactagatca acgaatccgc cgccacagtg caataagcat ccaaatagat
      721 aagaccaaac tgatgatcaa ggcgattccc catccgaaaa cggaatgggt aaagggtaac
      781 tggagattca ttccgaagaa tcctgtcaca atagttggaa cggtcaagat cagcgaccag
      841 accgtcaaaa atttcatcgt gtcattcaag ttgttattca gcaaattatt ataagtgcca
      901 gagagctggt ctaaaatctg cgaagctaag ttcgtcattt caactgcttg tcgtgcttcg
      961 atcagcgcat cgtccaactc ttctttttcc ttttctgaca acttgcgata aatagccaat
     1021 gccttgattt gttctaaaag tactacattt tgttttgttc ctgtaactaa gtaaaccaaa
     1081 ccgatctcta aatctgaaag ttgcagcaga ttcttgttcg ttgttttttc tcttaatttc
     1141 agattaagcc gctgacgttc actattcact tcctcgatta aaggaaaaaa ggaatcagaa
     1201 atcaaaaaca atgtacgaaa caataaactg tatacactca tgtctggcat tcgttccaaa
     1261 agcgatcgaa ttagtcgaat cacgtactcg gtattcggcg tggtaaatgt aaacaaaccg
     1321 tcttctttta aaataaaagc gataggacta gtttcataat gattatcgac tttttgctgg
     1381 tgcggaacat ttgatacaag cagtaacgct tcatcaaaag aatcgtactc tacgcgcgcc
     1441 cgttcatttt tatctagaga ataagtcagc atctcgtcac taatgccata ttcttctttt
     1501 aagtttttaa cagctagcac atcgttttgc tgtacattga tccaaaaatt acggtcttga
     1561 ttaaaatagt gtttttcccg catactctat cctcctgaca tttgtttcca gtataaagaa
     1621 aaaagtcgct caaataaagg tttacccttt atttgagcaa ctgtaaatca aatggctact
     1681 ttggtttggc gaatctctgc taatttttct tcgatcattt tcaagacttc ttcttttgct
     1741 tgaggatctt ccacaaaatt atagcggtct ccatcgattt ggatttttgg actttctttg
     1801 tattcttcat accattgatc gtaacgtctg ttcaattctt tgtaataatc gtatagactt
     1861 ggatcaaagg acaattgttc atacgaacga ccacgttttt cgatacgctc caacatcgta
     1921 tcaaaagata cacgaatatg aactaataaa tccggatgtt ttttatgggc agcataggga
     1981 agttcttcca tcatgttttc cagcagttca tcatacacac gaacttctgt ttctgttgct
     2041 cttcctagat ctgcatttag atggaaaagc agtgaatctt cataaatcga acggtccaat
     2101 acattattgt catctttcat tgcttgtttg atgcttgcaa aacgtttatt caaaaaataa
     2161 atttgcagca aaaaagcata ctgttcaggg tttgcataaa ataagggcaa gacttcatta
     2221 tcatcaatcg attcataaaa tgcctgacta tcaaagtgtt cagccatcat ttctgttaaa
     2281 cttgattttc cggcaccaat tgtacctgct aaaacgatca cgctcattta cctccagctc
     2341 acttcatcac taaatattgt gtttaactcc aaccttttta aatatacccc caatatctag
     2401 tagtgtcaat tgtatttttt tctagtcaaa gaagaaaaaa agtcaaaaaa ttcttaagaa
     2461 aaaagtgttt tttctttaga aaacgtattc ttagttttac ttctgagatg gttttagtaa
     2521 aataaaggag gaatgttttt tgagaccctt agtggacaaa aaaattcgtg aagcagcgca
     2581 actcgttttg ggcgctttat tttttgctta aaaatcactt ttacgtgaga aggagttaga
     2641 ttatggcaaa ctatggccaa ggagaatcaa gcggaaagat catattgatg ggcgagcacg
     2701 cggttgttta tggagaacca gcgattgcct ttcctttcta tgcaacaaaa gtcaccgcat
     2761 tccttgaaga gctggatgca atggacgatc aactggtttc ttcctactat tcaggaaatt
     2821 tagccgaagc tcctcatgca ttaaaaaata tcaaaaaatt attcattcac ttaaaaaaac
     2881 agcatgacat ccaaaaaaac ttgcaactga ccattgaaag cacgattcct gctgaacgtg
     2941 gaatgggatc aagcgctgca gtcgccacag cagtcactcg tgctttttat gattacttag
     3001 catttccttt gtctcgtgaa atactattag aaaatgtcca gctttcggaa aaaatcgccc
     3061 acggtaatcc tagtggaatc gatgcagccg ctactagcag cttgcagccg atttatttta
     3121 caaaagggca tcctttcgac tacttttctt tgaacatcga tgcttttttg attgtcgctg
     3181 atacaggaat caaaggacaa acaagagaag ccgtcaaaga tgtcgctcac ctctttgaaa
     3241 cccagcctca tgaaactgga caaatgatcc aaaaattagg atacttgacg aagcaagcaa
     3301 aacaagcaat cattgaaaat tcaccagaaa cgttggcaca gacaatggat gaatcacaat
     3361 cacttctgga aaagctgaca atcagcaatg attttcttaa tctattgatc caaacagcaa
     3421 aagataccgg ggcattgggt gccaaattaa ctggcggtgg acgcggtggc tgtatgattg
     3481 cattagcaca aacaaaaaca aaagcccaag aaatcagtca agcacttgaa gatgcgggtg
     3541 ctgctgaaac ttggatacaa ggattaggag tacataccta tgtttaaagg caaagcacgc
     3601 gcatatacca acattgctct aatcaaatat tggggtaaga aaaatgaaga actcatcctt
     3661 ccaatgaaca acagcctttc gttaacattg gatgcatttt atacagagac agaagtcatc
     3721 ttttctgata gctatatggt agatgaattt tatctagatg gcaccttgca agacgaaaaa
     3781 gcaacaaaaa aagtcagtca gtttcttgac ctttttcgta aagaagccgg cctctcacta
     3841 aaagcttcag taatcagtca gaatttcgtt cctaccgcag ctggattagc ctcctctgcc
     3901 agcgggctag ctgctttagc aggcgcttgc aatactgctc ttaagcttgg attagatgat
     3961 ctctctcttt caagatttgc tcgacgcggg tctggttcag cttgccgaag tattttcggt
     4021 ggtttcgtcg aatgggaaaa aggccatgac gacttaagtt cttacgctaa gccagtccct
     4081 tccgattctt tcgaagacga tttagcaatg gttttcgttt tgatcaacga ccagaaaaaa
     4141 gaagtgtcca gcagaaatgg gatgcgtcgg acagtcgaaa catccagttt ttatcaaggc
     4201 tggttagatt ccgttgaagg ggatctatat caattgaaac aagcaatcaa aacaaaagat
     4261 ttccaacttc tcggagaaac gatggaaaga aacggactaa aaatgcatgg aacgacttta
     4321 gctgcccagc ctccattcac ttactggtct cctgacagct taaaagcgat ggatgcggtg
     4381 cgacaattga gaaagcaagg cattccatgc tactttacga tggatgctgg ccctaatgtc
     4441 aaagttttag tggaaaacag ccatttatct gaggtacaag aaacatttac caaattattt
     4501 agcaaagaac aagtaattac tgcacatgct ggtccaggaa ttgcgattat tgaataaagg
     4561 gagattttta tgattgaagt atctgcacca ggcaaactct atattgccgg agaatatgca
     4621 gttgttgaaa caggccatcc agcagttatc gctgcagtcg atcaattcgt gacagtcact
     4681 gtagaatctg cacgaaaagt cggaagtatc caatctgcac aatatagtgg gatgcctgta
     4741 cgttggacaa gacgcaacgg agaattagtt ttagatattc gggaaaatcc ttttcattat
     4801 atccttgctg ctattcgctt gactgaaaag tatgcacaag aaaaaaacat tcttttatcc
     4861 ttttatgatc tgaaagtaac aagtgagtta gacagttcaa atggccggaa atatggattg
     4921 ggttctagcg gtgccgtgac cgttgcaacg gtcaaagcct tgaatgtttt ttacgcgttg
     4981 aatttatctc agttggagat tttcaagatt gcagcactag ccaatttagc agttcaagat
     5041 aatggttcct gcggcgacat cgctgctagc tgttatggtg gctggatcgc tttctcaacc
     5101 ttcgaccatc cttggctcca agaacaagaa actcagcatt ctatcagtga gttacttgcc
     5161 ctggattggc caggtctatc cattgagcca ttgattgctc ctgaagattt acgtttattg
     5221 attggttgga cgggtagccc tgcctctact tctgatttgg tcgatcaagt tcaccgttcg
     5281 agagaagata aaatggtggc ttatcagctt ttcttaaaaa atagtacaga atgtgtcaac
     5341 gaaatgatca aagggtttaa agaaaataat gtaacgttga tccaacagat gattcgaaaa
     5401 aaccgacaat tactgcatga tttatctgca atcactgggg tcgtcatcga aacgcctgct
     5461 ttgaacaaat tgtgtaattt agctgaacag tatgaaggag ccgcaaaatc ttctggtgca
     5521 ggtgggggcg attgcggaat cgtaattgtt gaccagaaat ctggcattct tcctttaatg
     5581 agtgcatggg aaaaagcaga aatcactcca ctgccgttac atgtctatag cgatcaaaga
     5641 aaggaaaacc gatgaatcga aaagacgaac atgtttcact agctaaagcc tttcatgata
     5701 aacaaaaaaa cgaatttgac ttcgtacgga tcatccataa ccctttgccg caaatagcag
     5761 tttctgatgt cgatctaagt acacaggcag ttgggtttac actaagcagc ccattttata
     5821 tcaatgcgat gactggcgga agcgaaaaaa caaaaaaaat caaccaagat cttgcaatcg
     5881 tcgcaagaga agcagatttg atgattgcca ctggttcagt cagcgctgcc ttgaaagtcc
     5941 cttctttagc cgatacttat acgattatgc gacaagaata tcctcacggg aaaatcattg
     6001 ccaacatcgg tgcagggact tctgtcgaaa gagccaaaga agctatccga ttgtttcacg
     6061 cagatgcctt acagattcat ttgaatgcac ctcaagagtt ggttatgcct gagggagacc
     6121 gtgattttac caattggaaa gtacttattc aagaaactca aacagccatt gacgtccccc
     6181 tcatcgtaaa agaagtcggt tttggcatga caagagaaac gctcaatgat ctagctgctt
     6241 taggagttca tacagttgat atcagcggtc gaagcggaac aagcttcacc cagatcgaaa
     6301 acgcccgtcg ctccaagcgg gaactgagtt atttagctga ctgggggcaa tcgacagtct
     6361 cttcattgct tgaagcaaat gaagcagaca cttctatgga aatcctagcc tccggaggta
     6421 tccgcaatgc ctatgacata tttaaagccc tttgtctcgg cgcaaatgcc gtgggtactt
     6481 caggaaccgt actgacgcat ctgatgaatc acggcgtaga agaaactatt atactgatga
     6541 agcaatggca agaagagctt cgtctgcttt atactatggt cggcgcaacg aataccgcgg
     6601 ccctacacca acaatctctg atcttttccg gaccagtgaa ggattggtgc gaagcaagag
     6661 ggatcgactt agtgaagtat ggaagacgca cagaaaagag cgtgggacaa aagtaaagaa
     6721 cacttttgtc tcacgctcta aacacgtaca aacggcggaa gtaaaagcaa ctccttcgga
     6781 aataagctga aattcacaaa aatttgaaaa gcaattttcg tgaattcctt cttatttctt
     6841 ggagttaaat gcttctgtcc cagcctcttt tttcgaataa atgatgttta atcagctgtc
     6901 cttcggtatt cgttcaatcc gctgatttca caacctctcc actaaacagt gtactaaagc
     6961 tcttttaagg ttgttttccg atataggcaa gtatgcctcc gtccacatac aagacatggc
     7021 cgttaacgaa atcagatgcg ctagaagcca agaagacaga tggtccagcc aaatcgattg
     7081 gctcgcccca gcgtgctgct ggcgtacgtc caacgataaa ttgatcgaat ggatgacgtt
     7141 caccgttttc ttgtgtttcg cgtaatggag cagtttgcgg tgtagcaata taacctggtc
     7201 caattccatt acattggata ttgtattgac cgtattcaga agcgatgttt ttcgtcagca
     7261 tttttaatcc gccttttgcc gcagcataag cactgaccgt ttcgcgtcct aattcactca
     7321 tcatggagca gatattgatg attttaccgc cgcctttttc gatcatatcc ggaataactg
     7381 cttttgaaac gatgaatggg gcatttaaat ccacgtcgat tacttggcgg aagtctgccg
     7441 catccatttc gatcatcggt gtccgtttga tgatccctgc attgttgact agaatatcaa
     7501 ctgaacctac atcttctttg atctgttgaa ccatcgcttg aaccgcttct tcatcggtca
     7561 catcgcagac ataacctttt gcatcgatgc ctgcttcttt ataatgcgct ataccttcat
     7621 caactgattc ttgattcaag ttattaaata cgatttttgc tcctgctgta gctaaagagc
     7681 gtgcaatctc aaatccaata ccatagacag caccggtgac taatgctact tttccatcta
     7741 aacgaaacat atccatacta aattccatca ttttctctcc cttatgctta ttttaattga
     7801 tccatttgca ccatatccat gtctgtatag gtgatatttt ctccgcacat tgcccagatg
     7861 aatgagtaat tgcttgtacc tacacctgaa tggatcgacc agcttggcga aataatggct
     7921 tgttcattgt ctacaactaa atgttttgtt tcatctggtt tgcccatcat gtggaacaca
     7981 cgtgtatctt cattggcata atcaaagtag acataagctt ccatacgacg ttcatgtgta
     8041 tgacaaggca tcgtattcca agcgcttcct ggttctaaaa tcgtataacc catttgtaat
     8101 tgacagcttt cgcatacatt tggatggatg tattggtaga ttttacgttc attcagtgtc
     8161 aggccttcac cagtctccat tggttttact tggtcgatac tgatttttac atttggatat
     8221 ttatgatgag ctggaacaga actaatatag aatttagctg ggttttcagc atcttgagaa
     8281 gaaaatacaa catgtcgtgt ttcttttccg atatagtatc cgtcttgttt tttcatttct
     8341 tctttttgcc catcgatctc gatgaatcct ggtccaccga tattgatcac acctagttca
     8401 cgacgctcta agaagtaatc aacacctagt tctttgtcta atgtgatttc taattctttt
     8461 tcagtaggtg tcactccacc aaagatcatt cgatcgttgt gcgtataagt caaactgatt
     8521 ttccctggtt caaatacctt ttctactaaa aattcttttc tcaattgttc cgttgaataa
     8581 tgacggatat cttctggact gtgtgtataa cgtgtttcca tttcttgcat tttcttctac
     8641 tccttctatc gaatgatttt tccagagccg catgctaaaa attgtgcgac ttcttcttga
     8701 ctaaattggt tgcagtcccc atggatcgta tgcttcaagg cagaagctgc cgtagcaaaa
     8761 tcaatgattt cttgcggaga catattggat aaaatcccat ggagcacgcc acctgcaaaa
     8821 gcatctccgc cacctactcg atccacgatt ggggtgattc tatggacttg ggattccaca
     8881 tattcatggt tcatccacaa tgtccccttc aattcatttt cacttgctga atgaacggta
     8941 cgcttggtcg aataaaacac ctgaatattc gggaactttt cctgcatttt ttgataataa
     9001 taaattagag gttgttcttc tgcttctggc gctttctcga tacctaacaa ataaagagca
     9061 tccatttttc cagctgagca gatatctact aaaggtaaaa gctgatggat tacttcgctg
     9121 gcttcttgct gtgtccataa ttttccacga tagttgatat cgaagctgat caggcagcca
     9181 gctttttttg cagcttctat cacctgtttc gtcatttttt gccatttttt agacaaagct
     9241 ggggtgattc ctgaaacatg aaatatatct attccttgga ataactcctc tagcgaccat
     9301 tccaaatgat ccatttcagc aaaacttgat ccggcacgat catagatcac tgaggcggcg
     9361 cgttcgccac taccagtttc catataataa gtacctagtc ttgatccacc agataatacc
     9421 tgtttcgtat ctactccata acattgcaag tgctttttga ctgcttttcc caatgcgtta
     9481 tcaggtactt ttgtagcaaa aatcgcttca tgtccgtaat tagctaaaga aattgctacg
     9541 tttgcttccc ctccgccata atgggcagcg aatcgttcac ttgaatcgat acgggttccc
     9601 tgctctgtgg acaatcgcaa catgatttct ccgagtgtca ctacttttcc cataagcagc
     9661 tacctcttga tttctttcat ttttgctgca tactgttgcg cgacttccgt tactttgtca
     9721 aaatctcctg tagctgcggg tgctaaaagg ttcccaccta ctccgactgt tacgacacca
     9781 gcatcgaacc actctttcat attgtccaga ctcacaccgc cagttggcat gatattgact
     9841 tgaggcatcg gcgccttgaa ggcagaaatg atacttggtc cataagcgct tccaggaaat
     9901 agtttgacga tatctacccc gcttttcagc gctgttttga tctcggtaat agtcatacat
     9961 cctggtaagt aaggaatttg atacagattg cacatctctg ccgtttcttg atcaaaggaa
    10021 gggctaacaa tatactctgc gccagctaag atagccaagc gagctgtgac agcgtctaat
    10081 actgtgcctg cgccaatcac tatttctggt tggtctttgt agaatgacaa aagttctttg
    10141 attacttgat ctgcttgagg gactgtaaaa gtcaactcaa taccagttag accacctttg
    10201 atgattgcgt ggcaagcatt caaagcttct tctttgcttt ttccgcgtac caccgcaatc
    10261 actccggcgt ttttcaatcg agataaaata tcaatttttt tcatcttctc cacctatttc
    10321 ctatttagaa attttatttt ataacttgga aatctatacc catattatac ggcagaaaag
    10381 aaaaattgca aacgcttttt tcattatttt tgaattcttt gctcgatttc gctttttgtt
    10441 tgcttgaggg cactgattat ttgttctttt gtctcatctg ttaaacgata tttcggcata
    10501 cttacactaa atgcaccaat gatttgttcg tttttcacga ttgaggctcc tatacaaaaa
    10561 atatcacgtt cgatttcttc atcgtcaaat gcgatgtggg tttcttttac cgtttggatt
    10621 tcctttttca accgtaatgc attggtgatc gtatattctg tgtaagggat caacggatgc
    10681 ttttcaagat aatcagtgta ctgctcttca ctgaattctg ctaatacggc tttgcccatc
    10741 gcagaattgt ataatggtcg ggtgattccg atttttgaag acatgcggat cgtttgatgt
    10801 tttggatcta gtttgttcac gtacaagatc tcattgttgt ccaatacccc taagtggata
    10861 gtctcatcga tcttttgctg cagctgttct aaaaacggta aagtcaactc taccaaatcg
    10921 atttgttcaa tgtttttatt cgcgtagcga ataagctttg cacctaaacg atagtttttc
    10981 tctgaatttt tatttacgta gccgatcatc aacaaagtat ctagtatttt caagactgta
    11041 gaagaggtca ttcccacacc ctttgcgatc gtctgcaaag agacatcttg gttttccgct
    11101 aaatagtcta gtattttaga ggctttgatc aatacagttc cataaggctt tttattttcc
    11161 atataatatt ctcctatttc tttataagaa aaattatagc ggaaatacca tcaatttaaa
    11221 agagatatcc agatataaac taccatttct ctttacaggc aatttaatgt tgaagatccg
    11281 cttcgttttt acatcaaact ttgatataaa gcaatgattt cttctactgt cgtttctctt
    11341 ggatttcctg gtgtgcatac atctcgcaaa gcatcttctg caattgctgg aatatctgct
    11401 tcttttacac ctaattcaga aatggtttct gggattccaa ccgctttgct caaccgatcg
    11461 atctcaccac aagccgcttc tcttacatct tctaaagaca tttcagctgc tcctttaatc
    11521 cctagaacaa gagcgatctc acggtacttt tctccagtat attctttgtt atatttcatg
    11581 acagttggca aaagtgctgc acacgctacg ccatgaggaa tgttgtacca tgcacttaac
    11641 gggtgagcca tcccgtgtac cagtcctaaa ccgacatttg agaagcccat tcccgcaata
    11701 tactgtccta atgccatttt ttctcgccca ttttgatcgc catctacaga agcttccaaa
    11761 gaatggccga tgatttcgat tgcttttaaa tgcagcatat cagtcatttc ccaagcgcct
    11821 tttgtgataa acccttcaat agcatgcgtc atagcatcca tacctgttga tgcagccaat
    11881 tttttcggca ttcccatcat catatcgctg tcgatgaacg cgacgattgg gatatcatga
    11941 ggatcaacac aaacaaattt tcggtgattt acttcatctg tgatgacgta gttgatcgtt
    12001 acttctgctg ctgttccaga agtcgttggt atagctaata taggtaaaca tggatttttc
    12061 gtatcagcaa caccttctaa actaatgacg tctgaaaact ctggattcgt caaaataatc
    12121 ccaatggctt ttgccgtatc gattggcgaa cctccaccga ttgcgatcaa acagtctgcc
    12181 tctgcctctt taacaaaagc cactccatct tttacatttt ggatcgttgg attaggtacg
    12241 atcccgtcgt ataaagcata agcgattgct gctttatcta gaagttctgt tacttttgtt
    12301 gctataccgt gctcgatcaa tcctttgtca gtaatgacag ctgctttgcc gaatcctcgc
    12361 tgctgaaatt cagggacgat cgactcaatc gctccttttc caaaatacga tgtttcattt
    12421 aaaatcattc gattactcat tttctattcc tcctaatttg tattattttt cacaataaaa
    12481 acgaaagaac cccaagcaac cggttgccca gttgcttgtt gctacagttc aaagactggc
    12541 atcaattccc aactgactgg agaggcatct ggatttgtct ccatgatatc ttccatgtac
    12601 ttccaccatt tttgattgat agatgtattt gccatttttt cccataactt ttcatcttcg
    12661 atcactaagt aaccaaataa caaacttgta ctcggatcaa gatagatcga atagtcgatg
    12721 accccgtgtt cacgaagtgc tgtacgcatt tctggccaaa gttcatcatg tctttttttg
    12781 tattcttctt gtttttctgg gtaaactttc atgcaaaaag cttttttcac catgtcagac
    12841 acctgctttc gtatgaactt cctccaaata acctgctttt ggagtgacac caaacgcatc
    12901 tgctaaatgc cacaggtttt cgtccgtgat tgtttgcaag attggtcctt gcgctttgac
    12961 gtacgtatag acttctgctg ccttttctgc tgtctcgatc aaaccaaaga cttcatccat
    13021 gtcttttcct gacccgtaga ttccatgttg tggccataaa accaatcgag tttctttcat
    13081 tttttcagct gttgcttccc caatctcatt tgttcccgga accatccacg gaatgatgga
    13141 aattccttct ggaaaaacaa ctaagcattc cgtacacatt tgccatagcg tacgactaaa
    13201 ggaacgttcg tctaattcat gcgtaaaact catcgctaat agatgactag catggcaatg
    13261 cataacgatc cgattatctg ggtctacttc taaacgggcg atatgactca tgaaatgact
    13321 tggcaactcg cttgtaggaa ggcattcgtt ttccagcccc cacaaaagtt ccagtgtttt
    13381 gccatcttca gcaactcgaa cgattccaag attctcggca ggttcgctcg ctacattttt
    13441 aaaatatctt cctgaaccag ttacaataaa atagcatcct gctaaacggc tggcatcaaa
    13501 aatcatcgag atgcggcgga tcactttttc aggatccaag aacggtgtga tctcttcttc
    13561 ttttagtaaa taagaaatat tcccgccatt tctttcatcc catcccaagc gataaagatt
    13621 cgacgtcgtt tcgatcattt ctttcacata aggcgcttgt aaaatatcta tttttttcaa
    13681 tatagccaca ctcctatttt cttaattcca acacgtcttt ttgatattcc tggacttctt
    13741 ccagccaatc caaaccaact ggaacttgat ttttgtaaca gaaataattc catacatcgg
    13801 catacgggaa atctttcaat tcttccgtat aagccattct tgaagtaaag tcaaaagcca
    13861 gctccatttc tttcaatcgc tcaactggtt ccagcatagc tttcagcagt gctttttgtg
    13921 tatttctcgt accgatgacc caagcagcga tacggttgat cgttgcatca aagaaatcca
    13981 gaccgatatt tgttttttcc aacaattcgt tacggactaa ttctttagcg atttcctgca
    14041 attcatcatc catcaaaacc acatggtctg aatcccaacg cactggacgg gaaacatgca
    14101 acatgattcc tttgctgaat aaagctaatg aagataattt attggaaatc acttctgttg
    14161 gatgaaaatg tccagcatct agacaaacaa gtttgtcacg agtcaacccg taacccatat
    14221 aaaattcatg ggaaccgact gtataagctt cagcgcctaa accaaatagt ttgctttcta
    14281 ctgcatcttg tacataccgt tcatctaact cttctgtaaa aatttcatcg agtgattcca
    14341 ttaaacgttc ccgtggggta aaacgatcaa tcggattatc tttcatccca tcaggtaccc
    14401 aaaagttatt gatacttgtt tgcccagttt ctttcccaaa gtactccgcg attttgcggc
    14461 ttcttttccc gtgttcgatc cagtattcac gaacttcttt atctggatga gccaatgtaa
    14521 agccgtcttt catcattgga tgcgaaaaga aagtcggatt gaagtcaaga ccgatttctt
    14581 ctttttttgc ccactctacc catttttcaa aatgtttcgg ctcaatttca tttagatcga
    14641 cagattcttc tgtatccaaa tagatagcat gaaggttcaa tttgtgtttg cccggtatca
    14701 acgaataagc cttctccaga tcttgtctaa gctcttcagg tgttcgtgcg gctcctggaa
    14761 aattccctgt cgccatgatt ccaccggtca attcgccatc cggtgtcaag aaacctttga
    14821 catcatctcc ttgccagcaa tgcatagaaa ttttgatgtc ctgtatcttt tctagtacag
    14881 catctgtatc tacaccgata gttgcatatt tttcttttgc ttgttcgtaa tttctttcaa
    14941 tcgtgttcat acgattactc ctttgatttt attcacgtac cattccatcg tgttttgctt
    15001 attttcatct gggtaaaaag tttcacatgg aaacgactgt ttgattacat ttcttgcttg
    15061 ttctatattc gaaaactgac ctgtactgag catttgcatg gcaacattcc cgattgctgt
    15121 ggcttcacta ggtcctgctt ctacaatgat tccggcataa tctgctgtca attgattcag
    15181 tagacgatta ttcgatccgc cccctacgat gtgcagcttt tccaatttcg ttccagttaa
    15241 gtgttctact ttgatcagct cttgtgcgta acaaagagca agattatcat acacacaacg
    15301 agcgatagct cccgatgaga cagggactgg ctgctctgtt tcaaaacagt attgctgaat
    15361 ctcttctatc atatttgggg gattcaaaaa tcgagggtca ttgatttcca tcacttgctg
    15421 cagcggtttt tcttttgcag caagctctgc caattccgca taactgtact cgtactcttg
    15481 cattcgggca acttcctgga tcaaccacat ccccatgatg tttttcaaaa aacgcaccgt
    15541 gttatgggca ccccattcat tcgtataatt ttcagaaaaa gcattgcgag aaacattggc
    15601 gatctttgtt tcaatcccta aaagcgacca tgtcccactg ctgatataac cccaacgttc
    15661 tccttgacct ggcgttccta atacagctga cgccgtatca tgacttgcta ctgtgataaa
    15721 ggtcacatct ggcaaatcat attttgaaaa ttgttctttt tgcagatctc ctagtatcgt
    15781 tcccggctct gtcaatggtg gaaataattc cttcgagaca ccgatttttt caagaagttc
    15841 tatttcccat tcttttgtcc ctgcattcag cagctgcata gtagatgcat tagttttctc
    15901 cgtcaccatg ttaccagtaa agacataccc taaataatca ggtatcagta acaatttatg
    15961 tgcttttgcc aaattttctt tttcttcagc aaacaattgg aacaaggtat tgaaaggctg
    16021 gatctgaatc cctgtctgct catacaactt atctagagaa tagatttcag aaaactgttc
    16081 tactgctcca ttggtacgct tgtcccgata agcaatcgga tcatttatcc gatccccttg
    16141 ttcatcaatc agacagtaat cgactgccca tgtatcgatc cccgcaaaaa ggcgatcaat
    16201 ccctgtctgc tttaattttt caaatccaat caaaatctct ttgataagat aatcgatctt
    16261 ccagcgatcg tgaccgtctt tgttccgaaa gccgtttttg aaccggtgta cttcttccaa
    16321 gatcaaagaa ccttttgcat ccctcgtact tttcattagt cgtccgcttg atgcaccgat
    16381 atcgatggca acaaatgttg gattcatttc tccacctctt ttactttatt gttgattagc
    16441 actttattaa taaagcgtta tcatttatta acaatgctat cataatacag aatcttatat
    16501 tttgcttcac actattttgg tatataattg cattatcttg acaagttggg agtgtttaca
    16561 tggattactg ggaaaaagcc aaccactcat ggtcggaaga ctcaaaaaga gtgatcttga
    16621 cgcctacaca aagaagcagg aatttatttt tttatatcca agaaatcggt tacttcaaag
    16681 caccaatccc ttactatact gaacgagcac atttaccttc ttacttgata aagtttactt
    16741 tgtctggcaa aggttcgctt acatataatg ataatcagca acagctaaaa gctggagact
    16801 tattttttat tgactgccaa gaatatcagc gttatcaaac gatcagcgaa gaaccatggg
    16861 aaatggattg gatccatttg aatggtcaga acgtccaatc attttatcag gagttcacaa
    16921 aagacggcca taacaccttc cattcaacag gggatccatc agaaaacaag atccaccatt
    16981 tgatcacaga attgatccac atgcaacaag gcacgaatgc ccgtaccgat ttccagtcct
    17041 ctgtagctat ccacgagttg ctgaatgaac tgattttgca aaagtatcag ctagatttcg
    17101 aagaagagga tattcccgcc tacgtttaca aactgaagca atacttagac gaacatttca
    17161 aagaaacgat tacacttgat caattagaac aacaattctt attgaataaa tatcagctga
    17221 gcaaagattt ttccaaattt atcggttctc caccaatcga ttatttgatc agcaaaaaac
    17281 tttcttacgc taaagacctt cttcggtata cagaatttac ggttcgaatg atttccgaag
    17341 aaatagggat tgagaatttt gcttacttta gccgcctgtt caaagcaaaa acaggactat
    17401 cgccgagaga ctttcgtaaa ttcagctgat tcatataata tgtacgtcat tttttcaaaa
    17461 tattttgaaa tatatagata aaaataaaat aaccgcagtt tctgcttcta tgtaaacaac
    17521 agcagctact gcggttattt tttagtgatc attctcattg ttcatcttca aaatgttcat
    17581 aatgaaccaa ctgtttctgt gtatcacgtt tcaaaaattc tttaggcgtt atgccgaact
    17641 ctctcttgaa tgctttcaga aaatgcggat aagaagaaaa accactttta ctatatacag
    17701 cactagagct gcggtattct cgcaacaagt gcttggcata gatcagcttt ttcttcatta
    17761 catactgatg aaacgtaaat ccagtgtact ttttaaattc tcgtgtgata tggtatttgc
    17821 tgacaaaaaa ctgcttttcc atttcctcta aagaaagcgg atgagataaa ttttttgaga
    17881 tatattgtaa catttgttcc acacgctcat taggaactac agcattctgt tcttgcgcac
    17941 tctcttcttt ttgtacaact tgattgagaa aaatcaagta ttctaccaga gcttgttcat
    18001 attttatgtc ttcaccgtaa atttttttat caggaggatg gtcgataaat gataattttt
    18061 gcttcaatac ttcctgttct atttgcaata cacgactcct cttctctccc attggttgaa
    18121 agcaagccga tagattagac catggcgtgg aacgactttc tagaaaagaa ggggtgacaa
    18181 agatatagac acgctcgaat acatctgaag attggcggac gatacgatgc aaatcattgg
    18241 aatggatgag cagcacactt cctgctttga tcgtaaattg tcgtccgttc aaataaaaag
    18301 tcgcttctcc ctttaatgta gcatggatct catagaaatc atgatgatga tagatcgttt
    18361 tattttggct gacgacatct ttgacatgat agatttcata ctgatcagaa accatcgtat
    18421 tgacttgttc accgctgatt ttcttttgga gcatgtgccg cacctccttt tgttcactta
    18481 tgcacaattt tattatacca cgttttttgt aatcaaaaag agctgctttt atatactctt
    18541 ataaaaaaga agagacgtgg catcttctag ccccgccccc tccattctaa atattagtta
    18601 accaacgtct tctttacatt attcaagaag acttcttcca taacgaatcc catcatcttt
    18661 tgtttcttca agaaccacat acaggtacgg acgattcttc atgatgattt ctttgatttt
    18721 tgtgtactcg atcacaccgt ctcccaaatt taccggcacg attttttcct gttcgacacg
    18781 aaaatctttc aaatgaaccg cacatatctt ttcaccaaaa cgttcaaaag cttcttctac
    18841 caattggact tgttcttgat aatcactact tgtgatcaaa ttggtcggat ctaaaatgat
    18901 tcctagatag tccgaatcta ctgcttggat cagctgctct acccttgcta aagaatacac
    18961 cggatgattc aaacctggtt ctatccccac catcatttgg tatttttctc cagcttttac
    19021 caagcgacgg ataacggaca cagcttcagc aaatgcttca tctgtgaaat tttcttccgt
    19081 atattggatt tccggcaaaa cacatccagt ttccgaagca accatcgacg caccaaagga
    19141 agaagcatag cgaagatact gctcgaactt tgtcagcaac tcttgtcgta tcgttaaatc
    19201 tggatgaatc atattgatat agcaacttaa aattcctacg gtcacttctt gcttttctaa
    19261 aactcgtttg acataatttc ccatcccaga attgatctca tttgcgccag aaggtatttc
    19321 aggaaacgaa agacctaagg cgagctgcag tgtatgaatc ccttgttctt ttgttttttc
    19381 tgcaagatct tctatcgttt ggacttcgga aagatcatgt cctctaattg taatgttcaa
    19441 cataactatt ctcctaactc agcatattgg gtagccacat gacgatttgc gggaagtaag
    19501 taatcaaaaa caagacgact aagataaccc cataaaaagg aagaagcggt ttcagcattg
    19561 cctctgcttt tacgcctcct acacttgcac cgacatatag tcctgtacct actggcggcg
    19621 tgatggagcc tacacacaga ttcatgattg aaaacaaccc gtaatgtaca ggatcaaccc
    19681 ctacacttgt gacgattggt aaaaatattg gtgtaaaaat caagatagca ggcgccacat
    19741 ccataaacat acccaccagt aataacacaa gattgactaa taacagaata ataaatttat
    19801 tatccgttac gcccataatc aacgaactaa ttgcctgagg aataccggta aacgccatgg
    19861 cgaaagacat catggaagaa gtagccaata agaacatgat cgtccctgac attgctactg
    19921 attgaaacaa catattaggt atatctttta gttttaccgt tttatagtaa aacatagcaa
    19981 tcaacaggga gtaaatgaca gctatcgctg aagcttctac tgctgtaaat atccccgtca
    20041 agataccacc gataatgatg acaatcaata gaaggctagg aatcgcctct tttattattt
    20101 ttccagcatg agccatctgt cctttttcga caacagggta tttattcttt ttagcaacga
    20161 tgaatgctac tagcatgatt cctagcgccc acaaagcgcc tacgagataa cctcccataa
    20221 acaaagcaga gatcgaagca ccaccagcaa caagtgaata catgataaaa gcagtacttg
    20281 gaggaatgac catacctgtc ggagctgacg cgatattgac cgctgtcgca aacttccggt
    20341 catatccttc ttccacttgc tgagggatca acactccgcc aatcgcggta gaagcggcaa
    20401 tggccgagct agagatggaa ccaaataaag cattccctaa cacattcgta tgagccaaag
    20461 cccccggcac gcgcccgacg aacaacatcg caaaatccac tagtttctta gctatccctc
    20521 cattattcat gataatgccc gagagaacga aaaacggaat agcgatcagc gaaaaactat
    20581 tgatacttcc caccattttt tgagctgaac taaaagcaga aacatcaaac ggtataacta
    20641 acaataaagt catcatcgat gagaatgcaa tacttatagc aatcggcatc cctaatacaa
    20701 gcaacacaac aaatacaaaa aataacacta atccggcttc tattgccatt ttattcctcc
    20761 atttttatat tttttcttga attgctggct tgttgcttaa tgtatcgatt agattgatca
    20821 ggctatagat aatgatgagt acccccgata caggtactga cagataaaca tatcccatag
    20881 gaatacttaa agaaggcgag atctgcccca ttgtcaatgt gacagcattc catccgccat
    20941 acaccatgat catcgcagca aataccagaa ataaactttg aacaacaact tctaaaattt
    21001 tacttttttt gccagttaat ttttcactta aaaccgttac ggctaaatgt gctttttgtc
    21061 ccacaacata cgcggaagac aacatggcaa accagacaag accgaatcga acaagctctt
    21121 ccgtgaccgt atttggattt cctaaaaccg ttctggaaaa tacttgccat aaaacaacag
    21181 cgaccatccc aacaagcaaa acagctccca ggatctctaa taccttgttt aaaatcattt
    21241 tcatcacagc tacgctcctt gctcttggat cttttgataa aggtctttgt aggtaggatc
    21301 gtttttgaat atatcatgaa gtggggcaac tgcctctcga aacggtgtat tatctacatc
    21361 attgaattgg actccatgtt cttcttgtgc taaagctttt tcttcttcaa ttgcttttgc
    21421 aaaagcttca atttcaaaaa ccgttgattc tttcgctgct tcttcaatgg ctttttcctg
    21481 ctcatcagtt agctgttctt tgatggcatc attcatgatg atgatatctg gcacacgtgt
    21541 atgctcatca taggaatagt atttagccac accaccatgt ccagctgtat acaagacaaa
    21601 ttcattgttt tctgatccgt tgatcaaatt ggattgaaga gacgtgtaca cttcatcact
    21661 tcccataggt acgggcgaac cgcctaaaag ctctaccatt ttgatagcgg tttcgctttg
    21721 catcacacgg atcttctttc ccttcaaatc ttccggcgta tggatcggac cgtctaccat
    21781 ataaaagctg cgctgaccag aatcataata ggtcaatccg gtaaatccta aatttttggt
    21841 cgattggtag attggctcca ttatttcttc attatccatc accttaaaga aatgttcttc
    21901 atcattgaat agataaggaa ctgaaaaaat cgaataatct ttagagaaac tttccaacgc
    21961 tgaggcactt acttttgtga aatctactgc tcctgactgt gtcaattcga tcagttcacg
    22021 ttctccaccc agttgtccat ctgggaaata ctggatctgt acggaaccat ctgttttttc
    22081 ttttactaaa cgcccaaatt cattcattgc atcaattact ggctggctgt tgcttgcata
    22141 agcaaagcgc aaggtaacta tctcatttac atctgcatct gcgacagttg ccacactaga
    22201 attatttccg cagccgctta gacctagcag acctaggcta agcgaacttg ctgcaaacag
    22261 cagtgatgtt tttttcatat gggtttcctt tcttttaaca ataagagacg agcaattctg
    22321 tcaaacaaag caccgttaac gactgtccat aaggcattgc tgtgattccg atattccgat
    22381 aaaaatctaa actgtccccc attcctgtcc cgattgaaac gttttgaact tctccttttt
    22441 catcgatttg ttcaagcaat ccttggatag cacgataagc gacttcttta tattcttgtg
    22501 gtaaataacg tttatggacc gctttcaaaa taccgtaagc aaatcctgca gttgcagaag
    22561 attctacgta agaagaagga tcatccaaca acgtatgcca taaaccgctt tcagactgat
    22621 aagtttttaa tgcacgcact tgtgcttcaa gtgtttcgat caataatttg cgcaatgcat
    22681 cttctttcga taattctaag atttcaatga tctctggaat agcaatcgtc aaccagcagt
    22741 ttccacgagc ccaaaatgct tcggcatagt tatgatttcc ttcaaacgtc cagccgtgat
    22801 accacaatcc tgttcgttta tccatcaagt atttgatatg gatcataaac tggtaacgag
    22861 cttcttctaa atattctggg cgattcaaca gtttcccgat ttttgccaaa ggaagcactg
    22921 tcatcatcaa tgtatcgtcc cacaactgat tcttattttc cggtccatat gtggcatgct
    22981 gtaacccgtc ttcatttgtc cgaggcatgt cattcatgac ccattctgcc cattgttcta
    23041 aataaggcaa atagcgtgaa tctttcgtgt cttcatacaa gtaagccata gtcaatagcg
    23101 gtgccattgt attgacgttt ttgggcggag cgccttcttc catacgatcc tcaaaccatt
    23161 cattgaccac ttgataagcg cgaggatttt ttgtcatctg gtaattttta taaataccat
    23221 atagaccgac accttgtggc caattccaca ctgtccagct tttgtcatct actttcagtc
    23281 catcaaagtc caacaaaaat tcaccattat cgtctttgat cgttgtcagg ttttcaacga
    23341 gcaggtcaat tttttctttc actaattctt taggtacaaa aatctcttct ttaataatca
    23401 tctttacgcc acttttttaa acgctttcat tttatatcct taatatagca gtaataccgt
    23461 ccactataaa tatcgctttt tgaacaaaaa ctgtctaaaa ttgacctaaa tgttaaataa
    23521 caaaagtaac tttcagttac ttggaaatta aaaaaagaac ttggagaaac aacgtttt
//
LOCUS       DACBZK010000040        23571 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.041, whole genome shotgun sequence.
ACCESSION   DACBZK010000040 DACBZK010000000
VERSION     DACBZK010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.041"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="IVD66_001663"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="IVD66_001663"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HAP6145886.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="IVD66_001664"
     CDS             complement(1172..1867)
                     /locus_tag="IVD66_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="noncanonical pyrimidine nucleotidase, YjjG
                     family"
                     /protein_id="HAP6145887.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="IVD66_001665"
     CDS             complement(1880..2596)
                     /locus_tag="IVD66_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HAP6145888.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3531
                     /locus_tag="IVD66_001666"
     CDS             2926..3531
                     /locus_tag="IVD66_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HAP6145889.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3856..4179
                     /locus_tag="IVD66_001667"
     CDS             3856..4179
                     /locus_tag="IVD66_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAP6145890.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4361..5731
                     /locus_tag="IVD66_001668"
     CDS             4361..5731
                     /locus_tag="IVD66_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAP6145891.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5861..7162)
                     /locus_tag="IVD66_001669"
     CDS             complement(5861..7162)
                     /locus_tag="IVD66_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAP6145892.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7392..9383)
                     /locus_tag="IVD66_001670"
     CDS             complement(7392..9383)
                     /locus_tag="IVD66_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HAP6145893.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9527..9793)
                     /locus_tag="IVD66_001671"
     CDS             complement(9527..9793)
                     /locus_tag="IVD66_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP6145894.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="IVD66_001672"
     CDS             complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="IVD66_001672"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HAP6145895.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="IVD66_001673"
     CDS             complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="IVD66_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HAP6145896.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13137..13700
                     /locus_tag="IVD66_001674"
     CDS             13137..13700
                     /locus_tag="IVD66_001674"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAP6145897.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13953..14474)
                     /locus_tag="IVD66_001675"
     CDS             complement(13953..14474)
                     /locus_tag="IVD66_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HAP6145898.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14477..15319)
                     /locus_tag="IVD66_001676"
     CDS             complement(14477..15319)
                     /locus_tag="IVD66_001676"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HAP6145899.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15312..16037)
                     /locus_tag="IVD66_001677"
     CDS             complement(15312..16037)
                     /locus_tag="IVD66_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HAP6145900.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16213..16509
                     /locus_tag="IVD66_001678"
     CDS             16213..16509
                     /locus_tag="IVD66_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145901.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17077..18669
                     /locus_tag="IVD66_001679"
     CDS             17077..18669
                     /locus_tag="IVD66_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750719.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP6145902.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18682..19422
                     /locus_tag="IVD66_001680"
     CDS             18682..19422
                     /locus_tag="IVD66_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP6145903.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19590..20939
                     /locus_tag="IVD66_001681"
     CDS             19590..20939
                     /locus_tag="IVD66_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6145904.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21067..21657)
                     /locus_tag="IVD66_001682"
     CDS             complement(21067..21657)
                     /locus_tag="IVD66_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAP6145905.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            21804..23156
                     /gene="brnQ"
                     /locus_tag="IVD66_001683"
     CDS             21804..23156
                     /gene="brnQ"
                     /locus_tag="IVD66_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAP6145906.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         6750 a         4746 c         4490 g         7585 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcgaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 agcacaggtg aaggtggcga accagaagtg atcggttcaa cagaagaata atactgaaac
     3541 aatcaggtgg tgttagaagc ggcgggtcag cagcttttaa cacgcctttt ttatttctaa
     3601 tcgtttattt tcatatgggg cttccacttt tgtaaatggc tttacaaacg aaaaatccta
     3661 atttaccaag cttttcctcg catactttta tcgtaccttt ataaaaattt atactttgaa
     3721 aaaaagtatt caattattgt tgcatttttc ctgattcttt attagaatga accctcgttg
     3781 aagtaagtat ttctagttta tcctaggatt aattataaaa ataaaacatt cgttgattcg
     3841 aaggaggtta aacagatgtt tgaaagtttt gatagcagcc gcaaccgtta cgcttcagtt
     3901 ggtgtcgtat caagtttgcc agatgaattg attgacagta tatggtttat tattgaccta
     3961 gatcttaagg gagtcattcc attagaaaat atattaacct ttgatttgat cgaaaatcgt
     4021 ggaaaagtga cgatgcattt ttctcaagca ggaagcaatg tggaaatgga tattgatttg
     4081 ccgtttgcct attcgaacca atttcctgct caagtatacg cctatgatga cggtacgaga
     4141 gaaacgatcc ttttaccaag tgagattaga caatattaag gtgatagata aacgtggatg
     4201 tcccttattt tacagaccag gccaagttgt tgattctttg actcaattct tggcttcttt
     4261 ttatggagtt tcataaatta tcattgattt ctaattggta ttctcaggat aaacgctata
     4321 tactactaac taaattttaa agatataagg agtttaaaag atgcgcgatt taacaaaagg
     4381 aagccccgct aaactgattt tgatgttcac tgttccttta ctgatcggaa atgtttttca
     4441 gcagttctac aatatgatcg atatgatcat cgtgggtcag acgctaggta aaaatgcgct
     4501 ggcagcggtt ggtgcaactg gaagcctgac atttttgatc attggctttg cccaaggttt
     4561 aacagctggt ttagccatta ttaccgcaca acgttacggt gcaaaagatt atcggggtct
     4621 gaagaaaagt tttgctgcta gtgttgtcat tagtcttgtc gtcactgtga ttttaactgt
     4681 cctaagtctc ctgtttattc gtccgatgct tcaattgatg caaactcctc ctgaaatact
     4741 tgatcaagca caaacattta tttcaattat tttattaggg atctttgcat cagtcagttt
     4801 caatttgctt tctaatgtca ttcgcgcact tggtgacagc cgcacaccac tattctttct
     4861 gatcattgcg gtcatcatca acgtcgtact tgatttgatc tttattatct attttggcat
     4921 gggtgtggaa ggtgcagcta ttgctacagt aatcgcacaa gtttcttcca gcgtactgtg
     4981 tctagtgtat atcaagaaaa aaatgccttt gttacagtta cgcaaaaaag atttcaaatt
     5041 tgaaaaagaa gagtttgctg tacacctaaa tgctgctttg ccaatggcgt ttcaatcttc
     5101 gatcatcgct gttggtgcta tcgtgttaca agcagcacta aatagtctag ggacagatgt
     5161 cgtagctgct caagccgctg ctggtcgtat cgaccaattt gcaaatcagc cgatgatgtc
     5221 atttggtatt gcaatggcaa ctttcactgc acaaaactat ggtgcgaaag aatatggccg
     5281 aatcttgcaa ggggtacgtc aaactttact gatgagtgtc ggatttagtc tcttagcagg
     5341 tgctatcgtc attttcttcg gtcatttctt tgttcaattg tttgttagcc catcagaaac
     5401 acgtgtattt gaattagcac aaacctactt caatatcaat gggtctcttt actggatctt
     5461 agcagtcctg ttcattttac gctacacact tcaagggctt ggacaaagca agatccctac
     5521 gatcgccggt atgatggaat tgcttatgcg ttcttttgca gctatcgttc ttacaggaat
     5581 gtggggatac ccaggagcag cagcagcttc tcctttagct tggatcggtt ctgttgccgt
     5641 gttgctttac tcttatatgc gttcgatgaa acaattgaaa cacatgggtg aagaggaaca
     5701 tttcacatta gaacatgcag aagcaagata gccttgatta aaagaaatcg ttgcggctaa
     5761 aaatgaaaac ttttattgaa aatatcttct tcgtttaccg aaaacaggtt ttttagataa
     5821 caaaaaggct gtgacaaaaa atgtcacagc cttttttctt ttattctatt tttctttccg
     5881 tggactctac tttgaaataa tcgatatgtg catgctggta ttctaatacc gtgaaacgga
     5941 atgatgcaat ctcaatgatt gttcctgctt ttatttcttt atatcggcta gaagcaaagc
     6001 ccgcaagtgt agtaaaattc gtttcttcaa actctggaat ctctacatga aaataacgct
     6061 ggaaatcatc taatgttagt ttgccggaga tgatataaga gccatctgac tgttccgcta
     6121 tcaatgcttc gtccaaatct gtctcatctc ggatttcccc gacgatttct tctaaaatat
     6181 cttcaatcgt cactaagccg cttgtccctc cgtattcatc ttttaagata gcaatatgct
     6241 ttcccttttt tcgcatgatc gtcaataatt tttttatagg gatcgtttca gttgttacga
     6301 tcggctcttc aatcaactgt tctactgtca gctggtcatc tttataagat tgcttgatca
     6361 aatctggcaa ggtgacataa cctaaaacat tgtcttttga ttctaagata accggatagc
     6421 gagtatgtcc ttgttcaatc gaagctttta tcgcttcttt gacggtttct gaagcttcga
     6481 atacttgcat ggacgtacgg tctacttgta tatcttttgc caaggtatca tcaaattcaa
     6541 acacgttttc caaataatga tattcttctt tggtcaactc tcctttttca taagaattca
     6601 atgcgactaa tgtcagctct tcttgagaca atgtctcttc tccttcagat acgagacgca
     6661 cacctaatag cttccctagc cctgcagctg aatgattcaa tacccaaata aaaggaaaca
     6721 ttactttata aaaataatga agtggtttaa ctacgaacaa gacgaccttc tccgtattga
     6781 cgatactata gctcttagga agcagttcgc caataaccac atcgatatac gtaactaaaa
     6841 taaatcccag cgccacagag attgtactgc taatagccga actaaaaggt agtttaccga
     6901 tcactggttc tagtaaagcc gcgacagatc cttcaccgac ccacccgatg atcaaaccgg
     6961 ttagcgtaat tcctaattga ctagctgata aatagttatc taaatggtgt gtaacatgaa
     7021 gagctagctt ggcgttcttt acattttcct tttctagttg ttccaatctt gatcgtctga
     7081 ttttcactaa agcaaattca cttgctacaa aaaatgaagt aattgcaatc atcaaaaata
     7141 aaataatgaa attgataacc atattctccc gcctttctct ttttctattg tacccttttt
     7201 ctacaaaaag attgaaaata atgcgtattc atatttagga ataaaaaagg agatgcggca
     7261 tttttcagcc acatctcctt atcacttcaa aatcattgcg ttacttgttg ctaaacagct
     7321 ttttcatgac ctctgataaa cggtgttcaa gtagctgaca ttcgacatta gttcaggtca
     7381 aagcgctact ttcacaaccg ctctttcaac catgttttcc gagtatttcc aatgataagc
     7441 ggaacagttt catgttttac ttcgctgtac tctagcccaa accatgtttc tggcgaggta
     7501 gcgatttttt tgattgccag ttttgcctgc atgatttgac gttgccattt tcctagagtt
     7561 gtcacattgg aaactacttc atcaatcagg acaaattgga aatcgccaac ttctcgccct
     7621 ggtgtcagag agtatctttg tggctgtttt ggcaaacggc cttgtttcat caaatcatgg
     7681 atgacttggc gaacatatac gttgatttcc tgttggaccc tgaaacctaa gaacagattc
     7741 acttggacaa taaaatcagt gtccatcata tctacttgat attctttcgt atatggctca
     7801 tccgtcactt ccacatgaac aaaccaatag actcgtgctc ttttaggccg tttatctaaa
     7861 atcgaataga tgaactgtcg gccaacttta tcttcagcca tatcaggaac caagaagacc
     7921 acatttgtct gatagattgg taaagaagta tcatcacgta attctctaag ctgcgggata
     7981 taatctctca aagacacatc ctcggttgac gattcgcgaa taatgttccc ttgttcccaa
     8041 ataaacatca cgactaagat gatcaaacca atcagaacgg ctacaaaacc gcctcggaag
     8101 aatttgacaa cacttgagat aaagaaaacg acttctatcg caccgaagaa aaaggtaact
     8161 aaatatgcaa gccaacgaga atgcccattt tggataagat aaaagtaaag cagtgctgtt
     8221 gtcatcaaca tcgtcacagt gatcgataga ccgtaagcag cttccatatg atgagacgtt
     8281 cggaatgtga caaccactag agaacaggcg atccataaaa tcagattgac tgctgggata
     8341 tacatttgcc cgatactgtt cccaggatac atgatcttta accgaggcag cagtttcaac
     8401 ttgattgctt ctgaaactag cgtaaacgaa cctgtaatca atgcttgcga agcaatgact
     8461 gcagcgactg ttgcaaaagc aacgccgatc acgatccaac tttgaggcat catttggaag
     8521 aatggattca ggttcttgat ttgctgtgct tcagggtttt gataaacatt caacaaccac
     8581 gcagcctgcc caaaataatt gataaccaaa caaattttga cgtaaggcca gctcagacga
     8641 atatttcgtt tgccgacatg tccaagatcg gaataaagcg cctctgcacc tgtcgtagcc
     8701 aggaaaatat ttccaagaat gaacaagcct aatttgttat ctgcactaaa aagcagctgg
     8761 atagcataat aaggattcag tgcacggata actgtccagt cttgactgaa gttcattaat
     8821 cccattacgc ctaaaaaagt aaaccaagcg aacatgattg gtccgaatgc ttttccgaca
     8881 atatctgtac caaagcgttg gaccatgaat aaaacaaaaa taataactaa agtgataatg
     8941 acgatcacgt tctggttatt accgaaccgg tcaaaaaact gcggaattcc tcgcaagcct
     9001 tcaatcgcag tcgttaccgt cacagcaggg gtcaataccc catctgctag taaggcagct
     9061 cctccgatca ttgcaggaat gatcaaatat ttcccacctt ttcggacaag tgtgtagagt
     9121 gagaaaattc caccttcacc atggttatct gcattcaatg caatcacgac atatttgatt
     9181 gttgtcagta gagtcaatgt ccaaaaaatc aatgagactg atccgataac aaaatcagga
     9241 ttgattcctg acaatccgcc attatcttca acaatcgatt tcataacgta aagcggactt
     9301 gtcccgatgt ctccgtagac gactcccatc gctacaagca ggccagccat tgatatcttt
     9361 ttggtattgt gcgttgttgc cacgtttttc cctcatttct tgttatatgg atatccttta
     9421 ggtaagcttg aatgatagat gatattctta tccatgacac ccgctttcct aaattgcttc
     9481 taattatcca agtaacacac tgaagtgtca acttatttga ataaaattat tctttctttg
     9541 gacgttctct gatacgtctt gccacaaatg aataaagagc aaggcaaaaa attgcaccca
     9601 ataatgctgg tatcaaataa aaaccgccga gttccggtcc cagtggtcct agtaaaaatt
     9661 cgccgagcca actacctaaa aaaccgataa tgatatttcc agatacgcct cccgggactt
     9721 cctttcctaa aattgcgcca gctatcaaac ctaatatacc gccgataaat aacgaccata
     9781 aaaaattcag catctccttt ccctccttta tccatatttc tcacttttat tttacgcttt
     9841 attcagaagg actccaaaaa tatgcgccaa gaaactccag aaaaaaagaa gttgtaacaa
     9901 aagtgttcag cttatttccg tagaagctgc ttctggaaca ccgtgaatca gaggttgtga
     9961 aatcagcggt ttgacctgag tattagagaa acaaacggaa aaatagttcc tcatattttg
    10021 ccgttttttg agctaatatc gagggacagc tgattgaaca tcgtttattg gagaggttgt
    10081 aaaaaagctg ttctgcatca agtaataaga acagccaagt aaaaacagct cctaatgttt
    10141 ttaacttggc tggacttatt accgcagatg caagcttttg aacaccgttt attcgaaaaa
    10201 aaaggactgt gacacggctt ttgtcacagt cccctttttt cgaataatta ttgtccccct
    10261 gtcaccttca cgatcacaag tacattattc ctatgaatta aattattttt cttcattttt
    10321 cgttgaacca tcttcgttca acattgcttt tcttgacaga tttacgcgtc cttgtttatc
    10381 gatttcagtt actttcacaa ggatctcatc acctagttta acaacatctt cgactttatt
    10441 gacacgatcg tttgctaatt gggaaatatg gacaagtcca tcttttcctt tgatcaagtt
    10501 gacgaatgca ccgaattttt cgatacggac aactttccct agataaactt caccaacttt
    10561 gacttctttg gtcaaatctt cgatgatctt gatagctttt ttgatcattt ctgcatcagc
    10621 tgaagcaata cttacttttc catcttgatc gatatcgatt ttcacaccag tttcatcgat
    10681 gattccgttg atcgtatcgc cgcctttacc gataacatct ttgattttag caggttcgat
    10741 ctggatcatt tcgatttttg gtgcatattg gcttaattct tcacgtggag cagcaatcgt
    10801 tgaagtcaat tcttctaaga tttccatacg tgcttgtttt gcttgagtta atgcttcagt
    10861 taggatttgt tctgtgattc cttgaatctt gatatccatc tgtaaagcag tgataccatc
    10921 ttttgtaccg gcaactttaa agtccatatc gccaagatga tcttccagcc cttggatatc
    10981 agttaggatc gtatagtttt caccatcaga aacaagtccc atcgcaatac cggcgactgg
    11041 cgctttgatt ggtacacctg catccatcaa tgctaatgtg ccagcacaga tacttgcttg
    11101 ggaagaagaa ccatttgatt ccaatacttc tgctactaaa cggatcgtat aaggaaattc
    11161 ttcttctgaa gggattactt gtgctaacgc acgttcacct aatgcgccat gtccgatttc
    11221 ccgacgccct ggagagcctg cacgtcctgt agaaccaaca gaaaattgag ggaaattgta
    11281 gtggtggatg aatcgtttgc tgacttccac ccctaaacca tcaatgattt ggtgctctcc
    11341 tagaggtgcg agtgtacaag ctgataaagc ttgtgtttgt cctcgtgtga acaaacctga
    11401 tccatgtaca cgtggcaata agctgacctc tgatgacaat ggacggattt catccaattt
    11461 acgcccgtca ggacggatct tatcgatggt gatcaattca cgtacgacat ctttttcaag
    11521 atcttctgtg atttgtttaa cttctttcaa caagtgatct tcatcttcat gacctgcaaa
    11581 tttctcagca taagcttcgc ggatatcgat cttcacctgc tcgatattat cttcgcgagc
    11641 aagtttttct tcagtcatta ctgctgcttt cattgtagcg taagaagcat caaagatttc
    11701 ttttttcaat acttcatcaa cttgcagtaa agtcacttcc attttttctt tccctactgc
    11761 ttgaacgatt tcttcttgga aagcaactaa ctctttgata gcgtcaaaac caaacagcaa
    11821 tgcaccaagc atgtcttctt ctgaaacttc tttcgcgccg ctttcaacca tattgatggc
    11881 ttgtttcgtt ccggcaacag tcaattcgat atctgtttgt tctgcttgtt ctactgttgg
    11941 attcaagacg tactcgccat ttacacgacc aacttctacg cctgcgattg ggccgtcaaa
    12001 tgggatatct gagattgata gtgctaaaga agaacctagc attgctgcca tagctggcga
    12061 gcagtctgtt tctacactca tcacgatgtt cgttacttgg acttcattac ggaagccttc
    12121 tgcaaacatc gggcgaattg gacggtcgat caaacgggca gtcaatgttg cttccgtact
    12181 tggacggcct tctcgtttga tgaaacctcc agggattttc cctgctgcat acattttttc
    12241 ttcataattg atcgttaatg ggaaaaagtc tgtatctttt gcttctttag aggccacagc
    12301 tgcacttaag actactgtat ctccataacg gactaaaacg gctccgtttg cttgttttgc
    12361 tagctgaccg acttcgattt gtaagggacg gccgccccat gtcgttttga atacttgttt
    12421 ttctgacata acttctcctt ttccttctcg tgaaagcaag acgctactaa acaaatgaaa
    12481 actgccgaaa gccgtctttt gagcagcttt catttggtta gtaggagtcc atctagcttg
    12541 atcacggaat tttacttaat tgatatacga gtaaaaaaag tgagattcat gtgaatccca
    12601 ctctttttga ctaaaattaa cgacgcaagc ctaaacgttt gatcaattcg cggtaacgtt
    12661 gaacgtcagt tttacgtaag taagctaaca agttacggcg gtgaccaact tttttcatta
    12721 ggccgcggta tgaatgatgg tcttttttgt gcacgcgtgc atgttcattc aagtggttga
    12781 tttcttcagt taatacagcg atttgtactt ctggagaacc agtatcccct tcatggcgag
    12841 cgtattcgtt gatgatttca ttcttgcgtt cttttgaaat tgccatttct ttcacctctt
    12901 tcgattattc ccctgcgact gagtaaaacg ttggtgattc gcttaaccaa gtggcaggtc
    12961 atgtgcctag agcacacagc tatactttac ctgaaaccgg gttgaaaatc aagtagttaa
    13021 tcattaagaa aaggtagttt tcaaacaatc ttactactac ttttccattt ttgtggtaaa
    13081 ctataatgcg aaaatagact tgaaacacag tcttttaaga aaggggtaca tattccatga
    13141 ttacaatgga tgatatcatt cgtgaaggaa atccgacctt acgcgaagtt gcaaaagaag
    13201 tttctcttcc attaagcgaa gaagatatct ctttaggaaa agagatgctt gagttcttaa
    13261 aaaacagcca agatccaatc aaagctgaag aactacactt acgaggcggt gttggcttag
    13321 ctgctcctca attagatatt tctaaaagaa tcattgctgt tcacgtacca agtcctgacc
    13381 cagaggcaga tggaccttct ctaagtactg ttatgtataa tcctaaaatt ttgagccatt
    13441 ctgttcaaga tgcttgttta ggggaaggtg aaggctgttt atctgttgat cgagaagtac
    13501 caggatatgt tgttcgccat gccaaaatca ctgtgtctta ttatgatatg aatggtgaaa
    13561 aacacaagat tcgtttgaag aattatgaat cgatcgtcgt tcaacatgaa atcgaccata
    13621 tcaacggtgt gatgttctat gaccacatca acgatcaaaa tccatttgca ctaaaagaag
    13681 gcgtattggt gatcgagtag agaattggca ggttccttcg atactatgct acaagaaagc
    13741 tttataaaaa aggggagtgc tcaaaagctg cacttccctt ttttatgttt ctccactaat
    13801 cgaaatttag atagacatct agaaatcgca attccaaaaa attctgtgta ttggatacgc
    13861 atcttttctt attttttctt atttcttcca tatgggtgtt tatctcagag atgatagaat
    13921 agtttctagg ataaaaagta gcagctacga tgttatcctt cgtagaggat tcctgcttca
    13981 gctagttttt gtttgatgtt tttcagcata tgcttttctg ggtagcggat cgtatgcaga
    14041 tggatgccgc ctgttaattc ggataacaaa gtagcattac ttttttgata acgtctcata
    14101 aaggaatcga tatcttgtgg cgttttgatg tgcaaagttc ctgctaactc accgtaaagg
    14161 ggatgttcca caattacatc aatgatttca ccaccatttt caacgattag tctcagttct
    14221 tcttctgttt gatcttttcc atgctggaca gcgattttac tgatgtgccc agtattggtt
    14281 tcttctgttt cgaggatata acctcttgct gttgccacga tacttttacc tgcagctcgt
    14341 agtaaagcaa tatcgcctac aatgatctga cggctgactc caaaagtttt cgcaaacttg
    14401 ctagcactca ctggtttttc tgtatttgcc aaggtttgca tgatttgttt tcgccgtgtc
    14461 tctccttcga tcacacttat tcctccttca ttttgttttg gtattcgcgc gagtgtttca
    14521 tcaaatcaac atacgtgtct gttattgttt ccttatatcc cttatttttc agcagactaa
    14581 caactttatc caatacttgc tgctctcttt ttgcatcata aactgcttgg ttttcttctt
    14641 ttttcacttg tcctatttta gttaccgtat ccattctttt ttctaataaa gcaaccaact
    14701 ctcgatcgat catatcgatc ttatgacgta atgtttcaag agactcttct gttagttctt
    14761 cctctactgt cttgatgata cgagcaggat ttcctgcaat cactacattg tcgggaaaag
    14821 atttggtcac aaccgaacct gcgccgacta ctacgttgtc ccctagagtg acacccggcg
    14881 tgacgataac tcctccgcct aaccaaacat tattaccgat tttaatgggt tttgcgtact
    14941 ccagaccgct gttacgtttc actggatgta gtggatgcgt cgccgtgtaa agctggacat
    15001 tcggagcgaa catgcagtta tcaccgattt caatcgtgct gacatctaaa aatgtacaat
    15061 tgaaatttgc ataaaaattc tccccaacaa atatattata tccgtaatca aaattgataa
    15121 ctggctccat atagattttt ttccctgtac ggccaaaagt ctctttcaac aattgggatc
    15181 gcagttccgc tgattctgct tggttgatga tttggctttg acttcttgca aacatacggt
    15241 cggcaaccag ctcaggatca ttggcaaaat aaagctcgcc tgcaatcatt ttttcttttt
    15301 cggttttgaa ttcagtcata atctgctcct aattcttgta tttttttgaa aacaaccgct
    15361 ccgtcttctt gaataaacgt ataaggctcc gctaaataaa caggcgtttg attgattact
    15421 aagattttgg ctgacggctg gcgaaactgt accagatcac aaaacggatg aacttgaaaa
    15481 ctcgttccaa caatgacgat cagctctgct tggctgacgg cataagccgc ctgctccatg
    15541 actccatctt gaaacccttc accatataac acgatgtctg ggcgtatttg tcctccgcat
    15601 gcttgatgtt tgtcgctgtg aagatattct ttccagtcta ccgtttgttg acattttcga
    15661 caatgacatt gatacagact cccatgaaaa ttgacgagtt gcgggctttt agcctttgcg
    15721 tgcaaaccgt cgatgttttg ggaaacaacc caaacatttt tttctttcgc tagatgtgct
    15781 atttccaaat gaatgatatt gggttttgct tcaggatgat aaatcttttt gacaaattga
    15841 tagaatttat ccggttcatt caccattgct tgatgactca gcaagtattc cggctgctcc
    15901 atcccgtggt agattcctga caaagatcga tagtctggca ctccagaagg tgtggatacc
    15961 cctgcaccgg tcaaaaatgt aatttgctga taagctaata tctcttttgc tgcttcgtct
    16021 actgttaatt gtttcatgtt ttgtcacctc actttccatt atagcccata ctcgaacaaa
    16081 tttattgttg aaaagtcaga aaaatgggaa taaaaaagtg ttatgggcat ttgagcaatt
    16141 tatcacaatg ttcactgaca aaagaatgaa aacgtgttac aatactgctg tataaaagtg
    16201 aggtgaatcg atatgttacc attctttatt tattggggcg ttattctggc ttgtatcgcc
    16261 tggttagcgt taagcgttta tttctctgtt ttttatcttg tacgcaaaga aaatggaaat
    16321 ctttgggctt ttgctttatt caacgtgatt gccgcaattg ttttagccat tacattagcc
    16381 gtatatcgaa catggggctg gggaatcacc caatactcaa gtttgattta tctaatatta
    16441 gccatttatg gcgtcgttgt tcttttgcaa gcgatcctag gacgtgagcc aaagaaagcg
    16501 gcagcttaaa tgatcgagat ggaactggac acaggaaatt ttctgttcta gttctttttt
    16561 tattgtatta catacatttt tgtgtataat tatactatcg tttgcaatgg atagatgatt
    16621 cacattttga ttgttttttc ggtaaaagta aagatttcta tatttatcag tattttttca
    16681 aaaaccagca gttatagatt gacaaagcct ctcgagtatc gtaaactttt tttgtataaa
    16741 taactgaata cgagatgcct caatcaatga ggtagaggtc gcgagaatca ttaaccctgt
    16801 ggagtgaagc aaacatggag aagcaggaat agggaggatc gccgaaatgt gcactttttt
    16861 gcttggagtg tatgttggga cgcaagttaa gagcttgcgg actgtcttag cagtgatgct
    16921 aagttgcgct atgttttgtg agaggtttat caccttatgg aattttagcg gcctttttat
    16981 atctataaat cggtcgcttt ttattttttc agataaagct ttaccgcatt tcatctagac
    17041 cgctcgtgta tcatataatc agaaagggag aaaaaaatga aaaaaaatat ggtttcagtt
    17101 gccgtactat ttgcttttgt cttctcacta ttcagtgtgg gatctctggc aaatgcagat
    17161 gaaaaaacac cgagcgatga gtttcgcgta ggtatggagg ctgggtatgc acccttcaac
    17221 tggtctcaac aaacagatga gaataatgcc ttgccaattc aaggccaaaa tagttacgcc
    17281 ggcggttatg atgttcaaat cgctaaaaaa gtagcagatg gtttagggaa aaaattagtc
    17341 atcgtccaaa cgaaatggga tggtctggct cctgcccttc aatcaggcaa gatcgacgcg
    17401 atcatcgccg gaatgagccc tactgctgaa cgacgaaaag aaattgattt taccgatcct
    17461 tattacgaat cacaattagt agtagtagtt caaaaagata gcaaatatgc aaaagcaaaa
    17521 agtttagcag atctttctgg agcaaagatc actgctcagt taaatacatt ccactatact
    17581 gtgatcgatc agataccaga tgtgcagaaa caacaagcaa tggataattt ctcagcaatg
    17641 agaacagctt tagcttctgg aatgatcgat ggttatgtca gcgaacgtcc ggaaggtgta
    17701 acggcaacta gtgtgaacaa agacttggaa atgcttgaat tcagcggtgc agatggcttc
    17761 cagacaaacc cggaagatgt tcagatttct gttggtatgc gtaaaggcga cccggatatc
    17821 caaaaagtaa accagattct ttctggcatc tctaacgatg aacgaaccaa aattatggac
    17881 caagcagtca aagatcagcc tgctgcaact gatagtgaag aaaaacctgg catcatttct
    17941 gatttcacta cgatttggaa acaatacggc aatatgttct tacgaggtgc tggacttacc
    18001 ttgttcatcg cattgatcgg gacagttgtc ggtactacac ttggattact gattggtgtc
    18061 ttccgttcgg tacctgaatc aggaaatgca ctgactcgct tcttccaaaa aatcggaaat
    18121 gcacttcttt ctatctatgt cgaagtattc cgcggaacac cgatgatggt acaagcaatg
    18181 gtcatcttct acggtctggc actcgctttt ggcatttcat tgaaccgaac gattgccgct
    18241 ttgtttattg tctctctcaa tactggagct tacatgacag agatcgttcg tggggggatt
    18301 tttgcagtag atgaagggca gttcgaagct gcgcaagcca ttggtatgac ccatggccaa
    18361 acgatgagaa aagttgttat tccacaagtt ttacggaata tcttgccagc aacaggaaat
    18421 gagtttgtta tcaatatcaa agatacagca gttttaagtg taatcggcgt agctgatttg
    18481 ttcttccaag gaaactctgc ttccggtgcg aatttccaat tcttccaaac atttacgatc
    18541 gtcgggatca tctacttagt catgaccttt acgatcacca gaatcctgcg ggcggtagaa
    18601 aagaaaatcg atggtccttc agcttatacc aagcttgaag aaatcgacaa ttcaaatttg
    18661 caggaataag gaggaagaat catgaatgaa aaaattattg aaatcaaaca tctaagaaaa
    18721 agcttcggtg aaaatgaagt attgaaagat atcagcgtaa cagtcaataa aggtgaagtt
    18781 gtgacgatca tcggttcttc cggttctggt aaatctactt tcttgcgctg tatcaattta
    18841 ctggaaaaac caacaggcgg cgagatcatt tataatggag aaaatgtatt agctcctaaa
    18901 tataatttac ctaaatatcg aacgaatcta ggtatggttt tccaatcctt caacctgttc
    18961 aacaatatga atgtcttgga aaactgtatg tctggtcaaa caactgtcct gaaacgagat
    19021 aaagaaactg ccaaaaaagt agcaatcgaa aatctggaaa aagttggtat ggatcgttat
    19081 atcgaagcca aaccagcaca attatctggt ggacagaaac agcgtgtcgc aattgctcgg
    19141 gcattatcaa tgaatccaga tgtattgcta ttcgacgaac ctacttcggc gttagaccct
    19201 gaaatggttg gcgaagtgct taatacgatc aaagacttag cacatactgg cttgacaatg
    19261 cttatcgtga cgcatgagat ggaatttgca aaagatgtat ctgaccgtgt catttttatg
    19321 gataaaggtg tgattgcaga agaaggtaca ccagaagata tctttgtcca tccgaaagaa
    19381 gaacgtacaa aagaattcct ttcacgtatt ttaaatgctt aggatcaata gctgattggg
    19441 acaaagagct gcggtgttta ccgcagttct tttttatgaa ttactcataa aaggtaaatt
    19501 tctgaaaatt ttggaatctt agttgtgttt ttcagaaaac tctcttaata tggaagtaat
    19561 taaacttttt tagttaggat gatttaaaaa tgaatgaaga gcaagaactg cagcgtggac
    19621 tgaaaaatag acatgtccaa ctgatttcta ttggcggagc gattggaacg gggttgtttt
    19681 taggttccgg aaagtctatc cagctagctg gcccttcgat attgctcgcc tatcttatta
    19741 ctggatgcat ctgttttttc attatgcgtg cgttaggcga acttctgtta tcaaacacca
    19801 ataaccattc ttttctggat tttgttgcag aatatcttgg caaaaaagcg gctttcatca
    19861 ctggctggac gtattggttc tgctgggtat cgattgcaat ggccgattta acagccatcg
    19921 gaatgtatgt acgctactgg gcgcctggtg ttcctcagtg gcttcctgaa ctgattgcat
    19981 taggtcttct tctttgcttg aatatggtgg ctgtctcatt gtttggtgag ttagagtttt
    20041 ggtttgcatt gatcaaagtt gtagcgatca ttgcctttat cctcgtagga gcttatatga
    20101 tcctcaccca ctatacgaca gatattggca cagccagtat cacgaatcta tggtctcatg
    20161 gcggattctt tccaactggt gcaaaaggat ttatcttagc tttccaaatg gtaacctttg
    20221 cttttgctgg gatagaatta gttggattag tcgctggaga aacagaaaat cctgaaaaag
    20281 tgttgccgga agctatcaat aatattccta tcaggatcat cttattttac ttaggatctc
    20341 tttttgtcat tatggcaatc tatccatgga acagcttgaa tccagataac agtccatttg
    20401 tagaagtatt ttcggaaatt gggatcacga ttgctgcttc cttgatcaat ttagtcgtat
    20461 taagtgcagc agcttctgcc tgcaacagtg caatatatag tacaggacgt atgcttcgtt
    20521 ctttagcgca agaaggcagt gcccctaaaa aattcaaaaa gttaacaaca catcatgtgc
    20581 cagggaatgc tttgacattt tctactatcg tcattttcat ttctgttatc ttgaattacg
    20641 tgatgcctag tgaagtattc acactagtaa gcagtattgc cactacttgt ttcttgttta
    20701 tctggagtat gcttgtctac acgcacatga aatatcgtaa aagtatcctc ggcaaaaaag
    20761 ctcattcatt taaaatgccg ttgtacccat ttagtaatta tctggtattt ctttacatgg
    20821 cctttgtgtg tgtcgtcttg ttcctaggaa aagatacgag aatcgcttta ttactaacac
    20881 ctgtgtggtt cttgcttcta ttactaatct atcatatgaa atatgaacgt aagaagtaag
    20941 aaagtagttg tgacagaagt ggtcagcttc gagaaataag aaggaattta cgaaaattgc
    21001 ttcttaaatt tttgtgaaat ttcggcttat ttcttggaga taaaagcttc tgtcccagcc
    21061 tcttttctat ttccccggaa acaaccgctg ataataggca tctgcttttt tataggaaaa
    21121 aatccaaata ccagatacaa aaaaacgtcc gaataacccg atcaacggta caaaaaagac
    21181 accggcaatc aagcataagt taatcatcat ggagataaga cttcgacggt cctttgacaa
    21241 aactctcacg acatgggaat ctggtttatt tgctttcatg atttgcctca tcaagatacc
    21301 aaaagaaaaa ctccacatcg tgtatactaa gacataagcc atctcaggcc aaaaagcttc
    21361 agggttacgc ccgacccaac tagtaacaga aggacataaa gtcagccaaa agagcaaaaa
    21421 gatattcgac cagaccactc ggtaattaat tcgttctgcc atctgaaata tacgatgatg
    21481 gttcacccag atcaccgcaa caaatataaa gctgatggta taagctaata atgtatttcg
    21541 gatgacccat aaagaatgaa agctagatgt attagggatc ttgatctcta atacaataac
    21601 tctcaaaaca atggctacca ctccatcagt aaatgcttct aatctcgact ttgtcacgat
    21661 gattcctcct cagatgattc agcgctttta ttttatcact tacgttatta aataaccatc
    21721 gttttatata gggaattttc tgaaaattgt tgcatatttt tcgaaatttt gttactttta
    21781 aaaaaaccgt aaaggagtta tgtatgacaa aaaaattatc atttaaagac tatcttttta
    21841 taggctccat gcttttcggt ctattttttg gtgctggaaa tcttatcttt cccgttcatt
    21901 tgggtcaaga agcaggcgct gctacctttt gggcgaatct aggtttcttg gttaccggta
    21961 tcggtcttcc cttcttaggg gtgattgcca ttggtgtatc gaaaagctca ggtgtatatg
    22021 aattagcaaa acggataaat caaacatatg cgatggtttt taccatcttg ctttacttag
    22081 ttatcggacc gttttttgct ttacctcgcc ttgcaaccac atctttcgag attggtttag
    22141 caccatttat cgatcctagc agacagacgc tatatctagc aattttcagt attgtatttt
    22201 ttgtgctggc ttggtggttt tcaagaaaac cgacaaagat attagattat gttggaaagt
    22261 tcctgaatcc tgcatttttg gttttattag gtgctttgct tctccttgct tttttgaatc
    22321 cactaggttc tgtaaatcaa gcgcctattc agccaaatta tcaagagcat gcttttttca
    22381 cagggtttac tcaaggatat aacacattag atgcgcttgc tgctttagca tttgggatca
    22441 tcattgtcac aacaatccaa aacatgggtg taacaaaacc tgctgaaatc gctaaagaca
    22501 cgatcaaatc tggtgcgatc agcattatat tgatgggaat catttatact ttgctcgctt
    22561 atttaggtgc tatgagctta ggtagctttg ctctaagtga aaatggcggg atcacgctgg
    22621 ctcagattgc tgatcattat ttaggtactt atggcagtat cttattagca tttatcgtta
    22681 tattagcttg cttgaagacc ggtattggtt tgattacagc ttttgcagaa acattcacag
    22741 atttgtttcc gcaaagaaat tacgcattct ttgttgcact tgctagtatc cttccttgtt
    22801 tagcggcaaa cgtaggcttg acgaatatca ttcaattttc gttgcctgtt ttgatgttca
    22861 tctatccatt agcaatgaca ctgattttac tagtgttagt tggtcctttg tttaagcagc
    22921 gtacggctgt ttatcgaatg actacttatt ttacattgat tgcttcgatt tttgatgggt
    22981 tgaacgcttg cccagaaact atcaaacaaa cacctattgt tcaaaatctt ttatatgttg
    23041 cggaaagcta cttgccgttt ttcaaattgg ggatggggtg gatcgtacca gcagttatcg
    23101 gttttgttat cggactgatt tggagtttcg ctaagaaaga agaagtagca gattgataaa
    23161 agaggttgtg aaagagacgt tcagccttga gcaataaaaa gtaattttga aaaatggctt
    23221 ctcacatttt tgcataaatt tgacttaata ccgagaaact gacttttgaa caccgtttat
    23281 tgagaggtcg tgaaaaagcc gcttagtttc aagtattaag aaatattttg tgaaaatggc
    23341 ttctcacatt tttgcataaa tttgacttaa taccgagaaa ctggcttttg aacaccgttt
    23401 attgagcgtc tataaactga cctgagtatt agagaaacaa aacggcaaag tagctccata
    23461 tactttgccg ttttgttttg aactaatacc gaagagaagc tgatcaaaca acatttcttt
    23521 tataatatag attttagaca tatatatgat ataaaaatag ttttcgcaaa a
//
LOCUS       DACBZK010000041        23143 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.042, whole genome shotgun sequence.
ACCESSION   DACBZK010000041 DACBZK010000000
VERSION     DACBZK010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23143
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.042"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            280..804
                     /gene="infC"
                     /locus_tag="IVD66_001684"
     CDS             280..804
                     /gene="infC"
                     /locus_tag="IVD66_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HAP6145907.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            876..1076
                     /gene="rpmI"
                     /locus_tag="IVD66_001685"
     CDS             876..1076
                     /gene="rpmI"
                     /locus_tag="IVD66_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HAP6145908.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            1129..1488
                     /gene="rplT"
                     /locus_tag="IVD66_001686"
     CDS             1129..1488
                     /gene="rplT"
                     /locus_tag="IVD66_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HAP6145909.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            1740..3047
                     /locus_tag="IVD66_001687"
     CDS             1740..3047
                     /locus_tag="IVD66_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HAP6145910.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAIFA"
     gene            3124..5253
                     /locus_tag="IVD66_001688"
     CDS             3124..5253
                     /locus_tag="IVD66_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HAP6145911.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKQQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            5228..5917
                     /locus_tag="IVD66_001689"
     CDS             5228..5917
                     /locus_tag="IVD66_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145912.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(6325..7011)
                     /locus_tag="IVD66_001690"
     CDS             complement(6325..7011)
                     /locus_tag="IVD66_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6145913.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(7147..7341)
                     /locus_tag="IVD66_001691"
     CDS             complement(7147..7341)
                     /locus_tag="IVD66_001691"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145914.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(7391..7831)
                     /locus_tag="IVD66_001692"
     CDS             complement(7391..7831)
                     /locus_tag="IVD66_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HAP6145915.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(7835..8680)
                     /locus_tag="IVD66_001693"
     CDS             complement(7835..8680)
                     /locus_tag="IVD66_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HAP6145916.1"
                     /translation="MLINEQLVKRIITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            8829..10247
                     /gene="pepV"
                     /locus_tag="IVD66_001694"
     CDS             8829..10247
                     /gene="pepV"
                     /locus_tag="IVD66_001694"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HAP6145917.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(10304..11251)
                     /locus_tag="IVD66_001695"
     CDS             complement(10304..11251)
                     /locus_tag="IVD66_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP6145918.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(11474..11824)
                     /locus_tag="IVD66_001696"
     CDS             complement(11474..11824)
                     /locus_tag="IVD66_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP6145919.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            12024..13103
                     /gene="pepA"
                     /locus_tag="IVD66_001697"
     CDS             12024..13103
                     /gene="pepA"
                     /locus_tag="IVD66_001697"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HAP6145920.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            13247..13567
                     /locus_tag="IVD66_001698"
     CDS             13247..13567
                     /locus_tag="IVD66_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAP6145921.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            13589..14053
                     /locus_tag="IVD66_001699"
     CDS             13589..14053
                     /locus_tag="IVD66_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP6145922.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            14258..14863
                     /locus_tag="IVD66_001700"
     CDS             14258..14863
                     /locus_tag="IVD66_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HAP6145923.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(14902..16191)
                     /locus_tag="IVD66_001701"
     CDS             complement(14902..16191)
                     /locus_tag="IVD66_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAP6145924.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENIKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            16619..17098
                     /gene="rlmH"
                     /locus_tag="IVD66_001702"
     CDS             16619..17098
                     /gene="rlmH"
                     /locus_tag="IVD66_001702"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HAP6145925.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            17183..17692
                     /locus_tag="IVD66_001703"
     CDS             17183..17692
                     /locus_tag="IVD66_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HAP6145926.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            17792..18442
                     /locus_tag="IVD66_001704"
     CDS             17792..18442
                     /locus_tag="IVD66_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145927.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            18893..19831
                     /locus_tag="IVD66_001705"
     CDS             18893..19831
                     /locus_tag="IVD66_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAP6145928.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            19844..20896
                     /locus_tag="IVD66_001706"
     CDS             19844..20896
                     /locus_tag="IVD66_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6145929.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            21162..21797
                     /locus_tag="IVD66_001707"
     CDS             21162..21797
                     /locus_tag="IVD66_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAP6145930.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYRLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            21988..22779
                     /gene="msrA"
                     /locus_tag="IVD66_001708"
     CDS             21988..22779
                     /gene="msrA"
                     /locus_tag="IVD66_001708"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP6145931.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
BASE COUNT         7376 a         4068 c         4789 g         6910 t
ORIGIN      
        1 ggaatcactg ctagaaagtc tgctaatcta atcattttca gaaaaggaag acaaactgta
       61 tgaaaaacat tgacaaaaag attagttttt gctatactat gatggttgag aaataaaagc
      121 agaagcaccc gcttctcgcc ttagttgata atgtcactgg gctagatagt tttcactggt
      181 tctattaggt gaagtacgcg cgggttctgt aagagaactc gtttttttat tgccgtttat
      241 tcggtaagct tttctttctc tcataatatt tggaggtgaa tgaccatagc aaaggatatg
      301 atggttaacg acggcattcg tgcacgagag ttacgattga tcggttcaga tggtgagcaa
      361 ttaggagtta agacaaaagc agaagcattg aatattgcag aacaagcaaa cttggatctt
      421 gtgttagttg cccctggtgc gaaaccacca gttgcgcgaa tcatggacta cggtaaatac
      481 cgtttcgaac aacaaaagaa agaccgcgaa gcgcgtaaaa aacaaaaagt gatcaatgta
      541 aaagaagttc gcttaagtcc tacgatcgac ttgaatgact tcaatacaaa acttcgtaat
      601 gcacgtaagt tcttggaaaa gggcgataaa gtgaaagctt ctatccgttt caaaggccgt
      661 gccattaccc ataaagaaat tggtcaaaaa gtcttgaatc gcttagctga agaaactgcg
      721 gatattgcaa cagtggaaca aaaagcgaaa atggacggac gcagcatgtt cttgacgctg
      781 gcaccgaaaa acgacagtaa gtaatttgaa tgactaactg gctgttggac agccgatagt
      841 cggataacga aagattttga ggaggaaata tagtcatgcc aaaacaaaaa acacaccgcg
      901 gatcagcaaa acgtttcaaa cgtactggta aaggcggatt gaaacgcttc cgcgcgttta
      961 caagtcaccg tttccacggc aaaacaaaaa aacaacgccg tcaattgcgt aaagcaagca
     1021 tggtttctag tggcgacttc aaacgtattc gccaacaact agcaaaaatg aaataagaag
     1081 tacaaataac agaatctgaa gatttatttt tattaggagg aattatacat ggcacgtgtt
     1141 aaaggtggaa cagtaactcg taaacgtcgt aaaagagtgc taaaattagc aaaaggttac
     1201 tacggttcaa aacacacttt atttaaaaca gcaaaagaac aagtaatgaa ttcatacaac
     1261 tacgcatatc gcgatcgtcg tcaaaagaaa cgcgacttcc gtaaattgtg gattgctcgt
     1321 atcaacgcag cagctcgtat gaatggcttg agctactcaa aattaatgca cggtttgaaa
     1381 gttgctgaaa tcgacatcaa ccgtaaaatg ttagctgact tggctgttaa cgatgcagca
     1441 gcatttactg cattggctga ccaagcaaaa gaagctttgg ctaaataagc taaacaatta
     1501 taaagaggaa agaagataac gaaaagttat gttctttcct ctttttttat ttacaatcct
     1561 ccatcaaatg aaacaggaca ataacgtata agtctaaaat agcataatta aggtttttta
     1621 attgaaaact gaacatttat ggtcaccctt taatgaaagc gctaactaca taagttagaa
     1681 tgagtttgac tgatatatta gtttgcttat cagaaaaaca aaatggacgg aggaataaca
     1741 tgagtgatat tattattggt attttgttag ttatctcatt ctttttcatg gtctggtact
     1801 gtgtaaaagg ctacaacttg atggtcggct ttgccatcat ggctactgta tggatgggat
     1861 tagcgctagt cggaaacacg ttttcaccaa acccggcgat ggaagggcaa ggagtaattg
     1921 atgtgttgac gcatatctat acgacggggc cagctgagta cgccaaatcg atcttggtaa
     1981 atgtcttctt tggtgccttt ttcgggcgtg ttctagtaga tagcggaatc gcagctaccc
     2041 tgattcgaaa ggtagttgaa cttggagggg acaagccaag aatcacgatg agcttactat
     2101 gtattgtaac cgctgttata ttcatgtcga tgacaggaat cggaccagtg atttctattg
     2161 cagttattgt gttgccaatc ttgatgtcat taggtatttc agtaccggtt gcactgttct
     2221 catttatggg ctcgattatg gctggaatct ttgctaatat cgtcaatttc aaacaatatc
     2281 aaacgattta tgctggtttc aatccagcgg ctgaaagcta tacttataat gactatttcc
     2341 aaattggtat gattgggatg attgtaagct tagttgtggt actaacggtc gctaatatat
     2401 caatgaacaa aaagaaacgc tatgcaatgg cagcaaacgt accagctgaa ggtggcgacg
     2461 caccaatgat ctcatggtta gccgtattat taccagtttt aggggtcgtt cttttagatc
     2521 ttccaatcat cttaggtttt attctagcag gtatctgggc attgctgttt actggaaaat
     2581 tgcgcggagg ttataaagaa atctgtcgtc agtttgcgaa attatttaca gatggcgcag
     2641 tagatgttgc accaatggtt ggtttcttga tgaccttagc gatgttcaat aattcagctg
     2701 cgtatgcttc tccttatttt tcagctattt ttggagattg gataccgcaa tcaccattag
     2761 tcttggcaat cgtatttgct atattgacac cactaggatt tttccgcggt ccaatgaatc
     2821 tagtcggttc aggctcagct attttagctg tcgtattagc tgttaatcca acgatgtcgc
     2881 cagccttttt gttcccgtta tttgcaatca caacgattgc tcctcagcat ttagatatta
     2941 cacaatcttg ggttgcttgg ggattaggtt atacaaaagt aacttctcga gaatatatga
     3001 agaaatccat cccaactggt tggatcatcg gagcgatctt tgcctgatca cgttcttatt
     3061 gtacgggaac gcctagtaaa caaaacgtcg ataaaaacga ttagatgaat ggaggaaaag
     3121 aaaatgaaac gttttgtgcg aatgggaatt gatgttggcg gtacacatac gaaagcagtc
     3181 gcaatcgata atgcgacgca cgaaatcatc ggaaaatctt cagtgaaaac aacccacgat
     3241 gatgtccgtg gagtagccgc aggtgtcgtt cagtcttttc aaaattgttt gcgggaaaat
     3301 aatatcagtc cagaagatgt tgtgtttgtt gcacattcta ccacacaagc gactaatgca
     3361 ctgattgaag gagacgtagc aaaagtcggc gtaatcggga tggcaaaagg tggattagaa
     3421 ggttttttag caaaacaaca aactagattg aacgatatcg atttagggaa taagaaaaaa
     3481 atagagattg tcaatgcatt cttacctgtc aaacacttaa atgtagaccg tgtttcagaa
     3541 acgatttctt ctttagaaag agaaagagcg gaggtcttgg tttcttctat ggcatttgga
     3601 gtagataatg gggaaccaga acgagttgtt tatgaagcag catcggtaaa atcgatccct
     3661 acaacgatgg cttctgacat cacaaaatta tatggattga caagaagaac tcggacagca
     3721 gcaatcaatg catctatttt accaaaaatg ctagatacgg caacctctac agaagattcc
     3781 gtacgagaag caggggtcaa tgtttctttg atgattatgc gcggagacgg cggagtaatg
     3841 gaaatcaatg aaatgaaaaa acgacctgtt ttaaccatgc tttccggtcc agcagcatca
     3901 gtcatgggct ctttgatgta cttgagagcg tctaatggtg tttattttga agtaggcgga
     3961 acaacaacca atatcggggt cattaaaaat ggacgtccag caatcgatta ttcaattgta
     4021 ggtggccacc caacatatat ctcttcatta gatgttcggg ttctaggtgt ggcaggcggt
     4081 tcgatggtac gggctaatca gtcaggaatc atcgatgtcg gtccacgttc tgcacatatt
     4141 gccggtctag attatgcagt atttacggag acagaaaaaa tcaaaggtcc taaggttgaa
     4201 tttttctctc ctaaagaagg agaccctgct gattacgtca aggtagtgat ggaagacgga
     4261 gaagaagtga ctattacaaa tacatgtgca gccaatgtcc ttggattagt gcaagaagaa
     4321 catttttctt atggaaatgt cccatctgca cgaaaagcca tccaagcatt agctgattat
     4381 tgtcatacga cggttgaaga catcgcagaa cagatcatgg aaaaatccta tgctaagatt
     4441 gaaccggtga ttttagaatt ggcagacaag tatcacttgg agaaagatca gatttctctt
     4501 gtaggtgtag ggggcggcgc tgcctcattg attacttact ttagtaataa aatgggtgtg
     4561 aaatattcga ttcctgaaaa cgccgaagtg atttcttcta ttggtgtagc acttgcaatg
     4621 gtccgagatg ttgtagaacg tatcatccct tcgccaagta aagaagatat acgatcgttg
     4681 aaaaatgaag cgatgaataa agcgattgaa tcaggcgcta caccagaatc gatcgaagtc
     4741 cacgtagaaa tcgatccaca gacttcaaaa gtaacggcta tcgctactgg ttctacggaa
     4801 gtgaaagcaa ccgatctaac caaggagatc acaacagaag aagcactaga gcttgctgca
     4861 gaggatatgc gattaaataa aaatgaagtt tgcttattgg aaaatacacc tttcttttat
     4921 gtatgcggcg aacagaatcg ttcaaaaaat gctggaagtc ttcggatcat cgatcaaaaa
     4981 ggatttatca aggtccaacg tggacatgct tcatgtatga aaacaactgc agccaattat
     5041 atgacagctg tcgaacaact ttgggaagat atggcagttt atcaaactga attgattgcc
     5101 cgaccagaat tttatctctg cttaggagca agagtctctg attttacagc gacggatctg
     5161 gaacaactac agcttttgat ggatctggaa gtatctacta tggaaccgga ggaagaagtg
     5221 atcgtcgttg ccggaaatat caaacaaaca taagttagaa gagttactaa acgaattaca
     5281 acagatcccc gaagaaattt ggggattcta ccagtttcgg cgagatttat tttggaaaaa
     5341 gattcctttg tccaagcaga aaattcttat acaacaatca atcgattgtg gtatcgaaac
     5401 ggcatgtagc atcaaaaaaa agtacccttt tgccgatgta ggagaaattt gtgaacaaat
     5461 ggctgttcca atcgtttcct gtgaatcaga gcaaataaac gaacgaatca cttttgcaac
     5521 ttatgcagaa gatgaaggga ttcgattgat gacggagccg ttagaaaaat taaaatgttc
     5581 aggactagct tcgatctcta aagaaacagc gcaagctttg attattggac atgaactatt
     5641 tcaccacatc gaagcttctg ttaagggaat ttatacgcaa agcgaaaaaa ttgtgctgtg
     5701 gcggttgcct ttttatacac atcaatcaaa cattcgtgca ttgagcgaga tagcagcgat
     5761 gagtttttca aaagagatga atcaaagcga tttttcgcct tatgtattag aggcagtctt
     5821 actttggcca tataatgaaa ttcgtagcca agggatctta gaagaaataa aaaaaataga
     5881 aaaaagatgt acggagtatg atttagatta caaataaaga gactgtgaca aaagtcgtgt
     5941 cacagtcctt tttttccgaa taaacgatgt tctcctgtca actcctcggt cacaagtcaa
     6001 aatattcaac aaacatgaga agctgttttt tgaaattgtt ccttgtgact cggagatgaa
     6061 cggcaggctc acgacctctt ggaaaacggt gttcaaaagc ttgcatctgc ggtaataagt
     6121 ccagccaagt taaaaacata agaagctatt tttacttggc tgttcttatt acttgatgca
     6181 gggcagcttt ttcacaacct ctcaataaac ggtgtgcaat cagctgaccc tcggtattag
     6241 ctcaaaaaaa acggcaaaat atgaggaact attttgccgt ttctttctct aatactcagg
     6301 tcaaaacgct gattccaaaa cctcttattt gatgggtctg tcctgaatat cttcaaaata
     6361 atcggggtaa ttatgaatca cgtattcttg ctcctcgata atcatatgta aatgcatcgt
     6421 gcaaagaaat ccgacttcat caaagttatg atcaatcatt gattgaagca ttgtctgatg
     6481 ttcatctaat actcgacccc agtctaattc tgaaatcgtc aaacgtaacc atctgaaacg
     6541 gttcaagtgc gtactataac tttctagcca atcccaaatt tctcgttttc cagcaatttc
     6601 ataacaagtt cggtgaaaat cagtatccaa atcaaaaaaa gcttttttat tttgagcgat
     6661 tactgcctga tcggtttgtt ctagtatttt ttctagttta gcttgatctt gcttggtcat
     6721 tttcgcactg cattcttgca ggatcggttt ttccaacttt tcccgcgtat aacgggctaa
     6781 tgaagcagat cggatatcga tttttgaaac ataagtgccg gactgtggaa tggtttttac
     6841 aagctcttga ttgcgcagtt ggatcagtgc ttctcgaatc ggtgtacgcc cgatagctag
     6901 ttgttcttct aacactttat cggagatttt acttccaggt gctaactcgg aataaatgat
     6961 ttgtttacgt atagattcat aagcttgctg ttgcaaatta ttgataacca tttaaccttc
     7021 ctttctatgc agatataatc tattataaca taaatcgctt acaaatcgtg tgggcataaa
     7081 aacacagtct gcaaaaaaag ccctgatagg catgcctatt agagcctcga aaagaaaaat
     7141 attgaatcaa tctggtcgta cctcttgtat cggtttgaca cgaccgccga ttcttttagc
     7201 aaaagcttcg gattcttttt tgtctttgaa aatgagcaga ttgtctaagt ttttttcccg
     7261 agtgcgacag ccagttttat cgatgtaacc gtgcattact ttaacgacat acatggggat
     7321 cacctgcttt tttcttttca ttatacgaac tactcgacac aatacaagaa aaatgcttag
     7381 acggtcttta ttaagaattt acatcatcca aagaagcgta cgcttggaat aactgatcta
     7441 actccggatt gactttgctc agcttcacta atcgttgcga atcagaaagt aaaaaacagt
     7501 gtttactact gccagtagtt tttaattttt tgtcttcagt tcccacaatt tcgtagctaa
     7561 aatccaaccg tgtccccgta tacttttgga tagttggatg gatgctcact ttttctccgt
     7621 aatggatcat ttctttatag ctgcaattta cttccagaac ggggatgatg atcccagatt
     7681 cttcgatttt tttataggga aaccctagat gtaccaataa ggctacccga gcctcttcaa
     7741 accagcggat ataattgctg tgatgaataa tccccatttg atctgtttca taataaaaag
     7801 gttctcgcac ataacctgta aatttctcca tgactcatgc ctcgttttcc attgattttt
     7861 tacaaaaata attcatccat ttcggaagtg cttcgctgat ttgtgtcggc aaaacaatat
     7921 attgttcttt tgccagctgg tctccaatga aactatgaag ataaatagct gctgcaatcg
     7981 tttggtcatt ttgaggaaac tgggctaaaa atcctgtgat catcccagct aaagtgtcac
     8041 ccatgccgcc cgttgccata gcagcagaac ctaaaggatt ggtgtagaag tgctggtgac
     8101 cataaatttt tgtctcatga cttttcaaaa cgagcacagc accgatttcc tgttgcttct
     8161 ttttgttttc tttatcccgt tgttcttgta tcggtagaga actcaaccgt tgccactcca
     8221 tttgatgagg tgtaagtaca gtttgttcgg gatagggtag caaaagatga ttagcagcaa
     8281 gtaaacttaa agcagagcca tcaatcacca gccattgttc ttttgattgg ttttctagta
     8341 cttgtttgaa acgttccaaa ctcttagaag aagtacccaa tccgggacca atcaagagta
     8401 catctgcttg ctttattacg gaaagaaact ggtcagtatc cgtccaaact acaatcattg
     8461 cttctggcag atgactgtga agagcactcc gatttttttc atcagttact acagtcgtga
     8521 gacccgctcc gctgtgtacg gcagctaaag cactcataat gattgctccg ccatattgtt
     8581 cattgccgcc aatcaaaacg atacgtccaa atgttccttt atgtgaaatt tttggacgag
     8641 gtgtgatgat tcttttcact agttgttcgt ttatcagcat ctaaaaacct ccttttactc
     8701 attatagcgt atattttttt tagagaaaaa cagataagaa aaggaattgt cagatttttt
     8761 gaactatttt tttctgtaat ttgtggtatc atgaacacga agacttaaat aagtggagga
     8821 ttaactttat gacaattgat tggcaaaaag aagtagaagc acgtaaagaa gacttgcttg
     8881 aagacttgaa aaatctttta cgtgtcaaca gcgagcgcga tgactcaaaa gtaacaccag
     8941 atgcaccatt tggacctgga cctcgcgacg cattgaaaca tatgttagct tatggcgaac
     9001 gtgatggatt taaagtaaaa aatgtcgata actatgcagg gcatattgat cttggcgaag
     9061 gagacgaaac gctagggata tttggacaca tggatgtcgt tcctgcagga gatggctggg
     9121 acacagatcc ttatgaacca gtaatcaagg atggaaagat ctttgcacgc ggatcaagcg
     9181 atgacaaagg tccaagtatg gcagcttact atgcgatgaa gatcattaaa gaacttgact
     9241 tgaaactatc aaaaaaagtt cgcttcgtag tcggcagcga tgaagaaagc ggctggggcg
     9301 atatggctta ttatttcgaa catgaagaag aaccagattt tggtttctca ccagatgctg
     9361 aattcccaat catcaatggt gaaaaaggaa atgtttcttt agctttacgc ttcaaaggcg
     9421 acaatgcagg agattatgtc ttgaaatctt ttgtttccgg acttcgcgaa aatatggtgc
     9481 caggaacagc aactgcagca cttcaagtac caagtgcaga tgcagctatc gcgatggaag
     9541 aagcatttta ccaattcatc gaagcaaatc cagtaagcgg aacgattgaa gcggacaata
     9601 cgtatgtaaa aatcgaatta gttggtaaag gcgcacatgg tgcaagccca caatctggta
     9661 tcaatgcagg ttctttcttg gcattgttct tagataacta tgaattccta ggatctgcta
     9721 aacaatttat ccatgtagca gctgcttatg tccatgaaga tttttatgga gaaaaactag
     9781 gagtcgctta tgaagatgaa aaaatgggca aattgacaat gaatgctgga ctatttgctt
     9841 ttgaagaaaa tggtacagag gaagcgaact tcatcaatat gaatttccgt tttccaaaag
     9901 gtgtaacagt agacggattg caaagtgaca tcgaacaaac agtggggcaa gaaggcgcaa
     9961 cagttactcg aggtgctcgc gtaatggaac cacattacgt accaatggat gatccattgg
    10021 tggctacatt attgcaagtc tatgaagacc acactggaga aaaaggctac gaacaaatca
    10081 tcggtggcgg aacttacgga cgtttgttga aacgtggcgt tgcttatgga gcgatgttcc
    10141 caggatatac tgatacaatg catcaagcaa acgaatttat gagtcttgat gacttgttca
    10201 gagcaacagc aatctatgca gatgccatct atcgtttggc gaaataatta attaaaaaga
    10261 ggatcaagaa ttgcaaatta tttttgcagt cttgatcctt tttttacttt ctactgtggt
    10321 attcatgata aacatgatat agattcaatt catattcttt cttagcgttc gtgacgactg
    10381 tatccaaaat caaccctgtt actaatgaaa gaagtgctaa agtcatcaat ccagtactta
    10441 aaatcgcaga agggatgcgt gtaataaagc ttgtcagcat atattcgcga atcacaggaa
    10501 tccccgtgac caatccaaat aaaaagaaga agatggtcca aatcccaaag aaaagcaaag
    10561 gcttataatc tttaaacatt ttaataatca tcatgatcac tttgaatccg tcagagaatg
    10621 tattcaattt tgattcgctg ccttcaggac gatcacgata atcgattggg atttcaacga
    10681 acttgaattt tttatctaaa gcatggatcg tcaattccgt ttcgatttga aaaccagaac
    10741 tcataatagg aaaacttttg acaaagatac gattgaatcc tcgatagccg gtcatgacat
    10801 caagaatttt tgttttatac attctagtaa ttgtatttct aacaaggtta tttccaaaat
    10861 cgtggaaagg tctcttattc tcatcaaagt aggttccatt tgataggcga tcaccaatga
    10921 ccatatctgc ttcaccagaa cgtaatttct cgagcaaacc atgtacagct tctgcaggat
    10981 aagtatcatc gccatctacc attaaataat agtcggcatc gatatcaaag aacatttggc
    11041 ggatcacatt tccttttcct tgacgaggtt ctttttttac gattgctcca ccttgaacgg
    11101 ccaattcgta tgttcgatcg gtcgaattat tatcatagac ataaatatct gcttctggta
    11161 attctcgttt aaagtctgca atgactgttg aaattgttgc ttcctcattg taacaaggaa
    11221 tcagaacagc aattttttct tgttgttcca tttttcactc tccttaacta tagaaaacaa
    11281 aagctaaatt aaaaatacct cataatcaaa ggaaatgcta gtttttcccg ctaaatatca
    11341 tttatttaaa aagaaaatac tggaatatat gtttggaaag ctctatctaa aaaaccaccc
    11401 actacaaaag aaggacatga tacctctctt ttgaatagtg ggtgcgtatt cgttctctca
    11461 cttttttgac gtattaatct gttgcacctt tttttcttga aatttctaat acggttcctg
    11521 tatgagcatc tgctaaaaat tcataataaa cagtttcgcc atcttctatt cgagaaagac
    11581 ctccccgata agcactcgac cgaacggcga atttcctaat aggttccttt tcaaaagaga
    11641 tccaagaacc ttcgattgca ccttctttta gaaaagatga cttgatattt tcaagtactt
    11701 ggtctgctga caatactttt ttgcgatgat accaaatcgt tgaagctacc ccgctcaata
    11761 atcctagacc gattccaact gctaacccgc ctttaaaata gcttagttcg ctttcttcat
    11821 acatgtggac atacctcctt cttctcactt gttactcctt gtgcttattt taccacactc
    11881 tcatattttc tttgaaataa ataaccgcta ccagaaaaaa taagctataa taaatacgat
    11941 cggtctgcag aaaaaatcat attttatccg cagatcaata taagtctgag aggagtttag
    12001 tctgaaattt agacgaatag catatggaag aaaaaacatt tcaacgaatc aaagagttaa
    12061 cagaattaca aggaacaagc ggttttgaac aagatgttcg cgcttatatg gaaagtcata
    12121 tggaaccgct ggtagatgag ttacagttag atggtttggg cggcattttt ggtctgcgcc
    12181 atcatgaaga agcggatgca ccccgtgtaa tggtcgcagc acatatggat gaagtcggat
    12241 tcatgctgac acaaatccaa gaaaacgggc tttttaaagt cgtacctcta ggcggctgga
    12301 atccttacgt tgtttctgct cagcgtttta cacttaaaac ctctactggt aagaattatc
    12361 catgtatttc ttcttccgtt cccccacatt tattgcgagg aacaagcgga caaaaatcag
    12421 tagaagtaac cgatattttg ttcgatgctg ggtttgaatc aagagaagag gcaatgagtt
    12481 acggtgtcct tccaggagac acaatcgttc cttacgctga aacgatcaaa acagccaacg
    12541 gaaagaatat tatcagtaaa tcatgggaca accgctatgg ctgtacaatg gtattagaag
    12601 ctttagaagc gttgcaaaat gaaacattag gtcatacatt gattgcaggc gcgaatgtcc
    12661 aggaagaagt aggcttgcgt ggttctaaag cttctgtcaa taaattcaag ccagatctgt
    12721 tctttgcagt agactgctct gcagcagatg atacagtgac gaaaaatggc acattcggac
    12781 atttaggaga aggtacattg atgcgtatcc aagatccagg tttgatcatg cttcctcgtt
    12841 tgcgcgagta cttgctggat atcgctgaaa caaacaatat cccttatcaa tactttgttt
    12901 caaaaggcgg tacagatgca ggtgctgctc atacacaaaa cgaaggaatc ccaagtacag
    12961 tgattggcgt agtgggacgt tatatccata cgcatcaaac gatgttcagt attcgcgatt
    13021 ttgaagctgc acgagaaatg ttgattcaaa cactgaaagg tttggataaa tcaacagtga
    13081 atacgatcgt atacggaaaa taatgcgata gtgaaactat aaaatctggc aaaagattgc
    13141 tttttgccag atttttttta taaaaagagg atcaatgttt gttagttcga aagaaaggtg
    13201 tataatttaa ttgaaaaata cataaacaga aagtagagga caaagaatga ttatcccaaa
    13261 tagtttagaa gaattagcag gctacgtaga aactggaaag agtgtatttt tctttactgc
    13321 cggctggtgc ggagactgcc gttttatcaa accgcaaatg cctgaaattg aaaatgactt
    13381 ttctgattgg caatttattg aagtagaccg tgacaagtac atagatgtag ccgctgaatg
    13441 gaacattttt ggtatcccaa gttttgtcgt gatccaagac ggaaaagaat taggtcgtct
    13501 agtgaataaa gatcgtaaaa caaaacagga aatcgaatcg ttcctagaaa gtgtaacaaa
    13561 aggctgacat ctgttaggag gggtcaagat gaatcaagaa tataagaata ttttagtagg
    13621 tatcgacggt agtgaacaag cacttgctgc tttcaaaaaa gcggtagaag tggctcgccg
    13681 taataatggg aaagtatatg tagcaaacgt aatcgatcag caattttata actttatggg
    13741 ctatgcacct attgatcaaa atctagtcga tcagcaaact gaaacagcca aggaaatgat
    13801 cgaagaatgt aaagaatatg ggaaatctgt tgattacaca aatatagaag gaattattgc
    13861 atatggttct gttcgtgaat ccatggcagt caaattgcca aaaaaatatg agatcgatct
    13921 aatcatggtt gggcagtcag gtctaaatgc agtcgaacgc tttatgacag gaagtgtagc
    13981 cagctacgtg atacgtcatt caccttgtga tgtcttgatc gtttctgacg aagaagaaca
    14041 gccaagtaat taagcaagtg gaacttgtac gaccttttta atcaattaac taaaacagta
    14101 aagggactgt gacaaaagtc ttgtcacagt cccttgttac gaataaatgg tgttccagaa
    14161 gaggcttctt cggaaataaa gcatgaaaaa aatttcatgc agtgaatgca attttttgtt
    14221 aagataaatc tcagcaaagg ataatggagg aaagaacatg atttttgctt ataacaaagc
    14281 acacgtcgga gacaccttga tggttattat agccgacgat aaaggaacag aaaacactgt
    14341 tgaacgcaaa tggaatgttg ctcggatcaa agatgaacaa ggtcaagttg ttgcttggaa
    14401 ctttttccat atctccgatc atctaacaat cgaagggaac ggccaagtaa gcttaacaga
    14461 tgaggaatta gcgaaattga atcgattgat caaagaagca ggattcgaag aacagcttga
    14521 agctgatcat gaaccgaaga tcgttgtcgg gtacgtaaaa acatgcgtcc cacatcctga
    14581 ttctgaccat ttatcgatta ctgagacaga agtagacaat ggtacagtat tgcaaatcgt
    14641 ttgcggtgca cccaatatcg aagctggaca aaaagttgtc gttgcaaaac caggagctat
    14701 gatgccagat ggaatgatga tctggccagg aactttgcga ggggtagata gctatggaat
    14761 gatctgttcc gctcgtgaat tgcatttgcc aaatgctcca gcaaaaaaag gaatcttagt
    14821 attgcctgag gatgccgtag tcggagaagc atttccaaaa taaagaggtt gtgacaagtc
    14881 tttgtcacaa cctctttttt attaattttc actattttga ttttgtttta atgccgattg
    14941 atcgatcgtc aattcaacag tagttgtttt ttctttcgag ccttcatagt aagtgatttt
    15001 gacagaatct cccacttttt tcttatacaa agcagattga agttctacac cagaagaaac
    15061 ttctttgtca tcgatcttag taatgacgtc gtattgtttc aatccagctt tttcagccgg
    15121 tgtagctgtt tggacatttg tcacgatgac accgttagtt acagatgaag gaatcttcaa
    15181 gatttgttct tgttgctgag tagaaacggc agataagtcg accattgtga tacctagagc
    15241 tggacgtgtc acttttccgt ctttttccag ttgattgatg atattcacta catcgttact
    15301 tggaatagca aatcccattc cttctacgct tacattagaa gtagattcag aagtacttgc
    15361 gatcttactt gagttgatac cgataacttg tccttcgata ttaactaaag gaccaccaga
    15421 atttccaggg ttgattgctg catctgtttg gatcgcattg atattgactg tttcgttcga
    15481 ttcattcgta cttgtcactt gtcggttcaa ggaagaaatg attcctgaag tgacagaatt
    15541 tgcatattca gatcctagtg gggaaccaat cgcaatcgca ggctcaccaa ccttcagagc
    15601 acttgagtca ccaaaagagg caactgtttc gactttgtct gaattgatct tcaacaccgc
    15661 taaatctgaa taagcatctg ttccaactaa ttcagctttt accttcgtac cgtctttcat
    15721 caagacttca agaccttgct ggccatctac tacgtgatta ttcgtgacta cataagcagt
    15781 attcccgtct tttttgtaga tcacgccgct tccttcacta taagcttcca aattactatc
    15841 atctgagctg ctactttctt cttgctgccc gaatagtccg ccaaaaccgc ttgattggtt
    15901 ttgactttgt aagttgataa cagaaacgac agcgtcttga actttatcta ccgctttggt
    15961 gatatcagaa tctacattga ctttgatatt ttccacaact gtttcaccgg cagaattctg
    16021 attgccgctt gtagcagtag aactattgtt gccagtgccc atcgctgcat aaaaaatgcc
    16081 agctgtcagt agtcctccaa cgatccctcc aacaagcccc agacctaact tacgccagag
    16141 gctattattt ttactttttt tcatctttgg tgtcacattt tttctatcca tgtgttcctc
    16201 ctccaattac attcatttat ctactgttag tatagtctta tttgttgact ttagtctact
    16261 ttgagactgt gaacttttta tgaaaaactt taggaaaaat cattgttttc agatgaaaat
    16321 atttgatttt ctttttccac agatactgtg taaaactacg cggataggat tggaaaaata
    16381 agggataaaa catatccaca gcctgtgtat aaagtggata aattcttata aaacgtatgt
    16441 ttgcctaatg aatgtgatga aataaggtaa aataacactg ttttctgtgg ataaacctgt
    16501 ggatgttgtg cataactgtt ggggaaatct ttttaacaaa aatagccaaa ataaacatat
    16561 agacgaaaaa attgattata ataaacaaag tgagcatgaa gaccaaagga gagaaaacat
    16621 gaatatcaaa attatctcag taggaaaatt aaaagaaaaa tacctgatcc aaggtatcaa
    16681 tgagtatgtc aaacggctga atgcctatgc aaaaatcgaa ttgatcgaag ttcctgacga
    16741 aaaagccccg gagaatttaa gcgaagcgca aatgagacaa gtaaaagaaa aagaagggga
    16801 acggatctta gcgaaaatca aagaacaaga atacgtctat gccttagcaa ttgaagggaa
    16861 aaatcctaca agtgaatctt ttgctaaaca aatcgaccaa ttaggtatcc aaggaaaaag
    16921 ccaccttgtt tttgttatcg gcggctcttt aggactcagc gaagccgtca tgaaaagaag
    16981 caatgctcag atctcttttg gaaaaatgac gtatccacat caattgatgc gtctgatcct
    17041 tgtcgagcaa atctaccgtg ccttccggat caatgcgggg gcgccttatc ataagtgatg
    17101 cggtttttat cattgatcct aaaaatctta gcaagacaaa aagtacgtaa gaaagtaaag
    17161 actaaatact tcggaggaac aaatgaataa caatgatagg ttattgcgat tgcgttatgc
    17221 gattgatttg aaagatacgg atttgattaa agcttttgag ctaggcggtg taccactgac
    17281 taaagaagaa gctcaggcgg tactgaccaa agtacaggat aagaacaaag ataatgcaga
    17341 aaataatgtg tatgaaaaaa ccatcaacaa ccaagttttt gacgcattcc taaatggcct
    17401 gattctcttg gcgcgtggtc cgcaaaaaga taagccgata gtagacacgc cgcaaaaaag
    17461 caaggaaatc aaatatatca acaatgtgtt gctaaaaaaa ttaaaaatcg ccttgtctat
    17521 gaccactgat gatattttag acgtttttgc tgaggcagaa atctatccat caaaaggcga
    17581 aatcggggca tttttgagaa aagaaggcca acgaaatttt aagccttgcg gagataaata
    17641 tatgcgtaat tttctcaagg ggttaggaat ttataatcgg agaaaagtat aaagaaattt
    17701 catgagaaat caaaacaatg gttgttttga tgagagctag tttttgtatg agattaaaat
    17761 attatcttaa tcgaggagct ggattggttt tatgaatgat gaatataaga atgatgaaga
    17821 taagatgctt tttgaagaga tagagaatcg atgtaggctc aattttgagc ttcggggaaa
    17881 gatgtcttta atacaacaaa aaaagtattt agcgaataaa tcagagttta ctctgggaca
    17941 tgttgaaaaa ttaatctcgg attggattag tagtagaagc gaatttacaa aaataaaaca
    18001 gccgattaaa tttgacatga aaaaactttt gttaaataag agtgagatag gtaatagaga
    18061 tcaatatatt agagctaaag ggcaagaaat aattgattca ttaggtgaaa tgaggtcata
    18121 caattatttg tatgtaacac atagagctga tggaatggtc attactgtgg ggaaatcttc
    18181 ttctaatgat atttttttag atggagatct tttttatcaa ctcaatacaa atcacttgtc
    18241 tggcactgaa aatataattt taaggacgga atatggcaat gaaatatttg caaaatatga
    18301 tgagatttta aaaaattatt tggactgggc ttggataatt ccggttgagt caggagatgc
    18361 taagaaactg gagagattat tgggcgatga actaattaat aaaaaagtac caattttaaa
    18421 ttattattcc catagacaat aaaaggctat ttttcatgat aatactagtt ataactgtaa
    18481 aaatggaaga aaatctggga aagaagtttt taaataagtg tattgttcga ttttaataaa
    18541 taataagcaa taccatccgt ctgtgttgcg caacatcgta ctacaatgaa tattttttca
    18601 caaaaagaaa atcatccatc gaatgaatgg aaggttttag tatacacgag gttaatgccc
    18661 cctcttttat aatcagagga gtgaggtttt ttctatgaat gtttctattt tcttattgct
    18721 agtctagttt ctcttacgat gaaattggga ttctattcca gtttttattg atttgctgat
    18781 aaaataactt gaatggtgga tataaacatg ataaataaga gaagaataac aaaacaaggt
    18841 tgtgaaatga ttctcaaatg aatataatag aaagaaaaag gaggaagaat caatgaaaat
    18901 agcaattgca ggcgctggcg caatgggaag tcgctttggg ttaatgcttc accaaagtgg
    18961 gaacgaagta ttattaatcg atggctgggc agaacatgtc caacaaatca aagagcatgg
    19021 attacaagca aattttaatg gtaaagaggt agaagcaaaa ctaccaatcg ttcttcaatc
    19081 cgaagtagaa aaagaagatc aagttgatct gattattcta tttaccaaag cgatgcagct
    19141 ggaaaaaatg ctgcaggata tccaatcatt aatcaaaaaa gatacagagg tcttatgtct
    19201 attaaatggt atcgggcatg aagatattat tgagaaattt gtaccaatgg aaaatatcta
    19261 tattggaaat accatgtgga cggcaggtct tgaaggtcct ggtcaggtca aattatttgg
    19321 aagtggttca gtagaattac aaaatttagg tgatggaaaa gaagcagctg caaaaaaatt
    19381 agcagacaaa ttgtctgaat caggattaaa tgctcatttt tctgacaata ttcactattc
    19441 tatttatcgc aaagcatgtg tgaacggaac aatgaacgga ctatgcacaa tcttagacgt
    19501 taatatggct gagctaggaa aaacatcgac tgctcataaa atggtggcga cgattgtcaa
    19561 tgagtttgcc aaagtagcag cagtagagaa gattgaacta gatgtcccag aagtcattgc
    19621 acattgtgaa tcttgttttg acccggaaac aattgggtta cattatcctt caatgtatca
    19681 agacttgatt aagaaccatc gattaacaga aatcgattat atcaatggcg caatttctag
    19741 aaaagggaag aaatatggtg ttgcgacgcc ttattgtgat ttcttgactg agcttgtcca
    19801 tgcaaaagaa gatagtttga acgtaaaata aaggagagat tgaatggaaa cttcacaaaa
    19861 aatatcaccg aaaatttttc tgaataaagt cctcgctggt acagcaacag gaatcattat
    19921 tggattgatt cctaatgcag tattaggtgc cattttaaaa tattttagtg cgtatccctt
    19981 tgcggtaacg atcgcacagt tagcagttat ttttcaacta gcaacacctt tgatcattgg
    20041 tggtttgatt gccttacaat ttggatttga tccgatgaga atgatggttg tagccggagc
    20101 ttcttttgtt ggttctggtg tagtcaaatt cacacctgat ttgggtgaaa cgggtgttta
    20161 cgttggtgct ggtacaggcg atattattaa tacgatgctg acagcatcga ttgctgtcgg
    20221 gctgatttta ctgattggaa atagttttgg gtcagtgtcg attgtgttaa caccgattgt
    20281 tgtaggtgta ggtgcaggtt tacttggttt ttatttattc ccttttgtaa cagcaattac
    20341 ttctgcaatt ggatcattga ttaataactt cactacctta caaccgctgt taatgtctat
    20401 cttgattggt tgttcctttg cctttttgat tatctctcct atttcaacag tagcaatcgg
    20461 aatggcaatc caactagatg gtgtttctgc tggtgcggct gcgatgggcg tagctgcaac
    20521 cacttttgtt ttagtagtga actcttggaa ggttaataag tcaggtgtga caattgcgat
    20581 tgctttaggc gctatgaaga tgatgatgcc taatctattt agaaaacctg tgattcttat
    20641 tccttgttta gttagtgcag tgattacagc tattcctgtc gctctatttt ctatttcagg
    20701 tacgcctgct tctgctggtt tcggcgtggt cggacttgtt ggtccgttgg cttctttaga
    20761 tgcagggcta aatggctttc ttgttgttct ttgttggtta gtcatccctg tttttgcggc
    20821 actaattact caatttttat gcgagaaagt atttaaactg tatgatcgag aagaagtctt
    20881 caaattttta ggctagtaga ttttactaag aaattttcaa tcaatggatg cgtaagtgag
    20941 atgtcaacaa catctgactt acgttttttt gcctttttga gtaggagatt gatgctgaca
    21001 actgaactct tcagtgccat tcgatttttt aaaatgtaga agaaactcac ctttatgtta
    21061 ttgattgttc aaaaggcaac tagaataaaa atatgtgtta aaatgagaaa aaatttgatt
    21121 gttggatgta tcgaataatc actaaaaagt aggagaagaa aatgattttt ttgcaaaaat
    21181 atggttttta ttttttatta ttaggtgtga ttagtgattt atcgacaccg tatatccttg
    21241 gcctttttta tcccaaactg aatcaaatga ctaccgtaat tagtgtgttt ggtgacgtag
    21301 atagtccagt cagacgtgct ttcttggtct ggtcagttgt atctggactt ttttttgttc
    21361 tttcgttgcc tgcgttgtat cacctattta ttggaacatc aaaaacactt gcaatacttg
    21421 ctgttgcaac agttggttta tatgggatag gtgattgtat ttttactggg ttattcagta
    21481 tcaatacgaa tgaaagctct tggaatctat cgacttggat ccataatata ggttctgggc
    21541 taggctatgc aggctttcta cttttcccat tgttacttgt tctgctttat cgtcaaagtg
    21601 gtcaaggtac gcttagccat ttttatcttg ttttaacagt tattagttta ctaattgcag
    21661 gtctttacag attagcacgg attccgtcga ttagtcagtt tgccttcttt aagcaattgg
    21721 gcttctttca acgcttaagt tttttcttta actatttgcc gatgatttgt ttaagttttt
    21781 ttcaactacg aaagtagaaa aagcagtgtg aagctgatta agtaaaagaa tttctctatg
    21841 ggtaaccatt cgtgtggatg tgttcgacta agaatagaga tgaggagagc gaaaagcaag
    21901 ttagtcttaa cttgttatgc gttgtgctaa atttcaggta gtcatttttt gaatgaataa
    21961 gaagaaaact tgaaagaggg tgacttcatg ttagatgtgg agcagatgga aatagacctt
    22021 tataatatta ttttaaatcg aaatacaaga gaatgggaaa gaacacaatt tgaagaggca
    22081 aaagaagacc tagcaaaaat gtcgataaag caggtgatag aaaaactaga ggtcaacttg
    22141 cgtccgctag cactacgaga taatttgaca ccagatgcga tggattttta tttaagaatc
    22201 acaggggagt cagcgagtgc aaaggcttat gattatgcca aacataagat aacttcaccc
    22261 ttataccaag aacgggcgat ttttgccggt ggctgtttct ggtgtatggt tgagcctttt
    22321 gaaacaaaac caggtgtaat ctcagtgtta tctggttata caggtggaga gaccaaaaaa
    22381 ccaaattacg atcaagtcag tggtggatat actgggcatg ttgaagctgt tgagatcata
    22441 tttgatacac gtcaaataac ctatgaagag ctgttggaga tttattggca aatttcagac
    22501 cctacagatg cctttggtca atttcaagat cgggggaaac aatatcgttc aattctattt
    22561 gttgttaatg aaaagcaaag gcaattggct gaaaaatcaa gagaacaact gattcaatct
    22621 aaccgattta gccgtcctat cgttacagag attcgccaag caaagacttt ttggccagct
    22681 gaaaatcatc atcaacaatt ttatcagaag caacctaaaa gatataaaaa gatcaagcat
    22741 tcgcatcagc ttcatttatt ttttcagcga catagataga ggaaggttgt ggcgcaaagc
    22801 gttcagctcc gacaaaataa tgagcaactg acaaaaatag cttttcatat ttttggacag
    22861 ttatgaatta tttcgaggag ttgctttgag aacaccgagg aaaaggttgt ggcgcaaagc
    22921 attcagcttc aagtcgcaag gaaacaggag gtatgacaag tcttttgtca caactcctgt
    22981 ttttttacta gcctttattt ccatgtgaaa gagaattcga attgtagaat cttgattttt
    23041 ctatggaatt ttgtagagaa tcatcttgat aattaataga cacctaatcg aattccacat
    23101 taatgatgaa ctaaattccg tataaaagcg caaacaataa cta
//
LOCUS       DACBZK010000042        22855 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.043, whole genome shotgun sequence.
ACCESSION   DACBZK010000042 DACBZK010000000
VERSION     DACBZK010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22855
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.043"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(104..1336)
                     /locus_tag="IVD66_001709"
     CDS             complement(104..1336)
                     /locus_tag="IVD66_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAP6145932.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1591..2160
                     /locus_tag="IVD66_001710"
     CDS             1591..2160
                     /locus_tag="IVD66_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6145933.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2338..2778)
                     /locus_tag="IVD66_001711"
     CDS             complement(2338..2778)
                     /locus_tag="IVD66_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAP6145934.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2936..3700
                     /gene="map"
                     /locus_tag="IVD66_001712"
     CDS             2936..3700
                     /gene="map"
                     /locus_tag="IVD66_001712"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HAP6145935.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3732..4655
                     /locus_tag="IVD66_001713"
     CDS             3732..4655
                     /locus_tag="IVD66_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HAP6145936.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            4731..5870
                     /locus_tag="IVD66_001714"
     CDS             4731..5870
                     /locus_tag="IVD66_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HAP6145937.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            5863..6663
                     /locus_tag="IVD66_001715"
     CDS             5863..6663
                     /locus_tag="IVD66_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP6145938.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            6663..7490
                     /locus_tag="IVD66_001716"
     CDS             6663..7490
                     /locus_tag="IVD66_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP6145939.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            7468..8202
                     /locus_tag="IVD66_001717"
     CDS             7468..8202
                     /locus_tag="IVD66_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP6145940.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            8302..9168
                     /gene="rfbA"
                     /locus_tag="IVD66_001718"
     CDS             8302..9168
                     /gene="rfbA"
                     /locus_tag="IVD66_001718"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HAP6145941.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            9182..9754
                     /gene="rfbC"
                     /locus_tag="IVD66_001719"
     CDS             9182..9754
                     /gene="rfbC"
                     /locus_tag="IVD66_001719"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HAP6145942.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            9776..10804
                     /gene="rfbB"
                     /locus_tag="IVD66_001720"
     CDS             9776..10804
                     /gene="rfbB"
                     /locus_tag="IVD66_001720"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HAP6145943.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            10902..11753
                     /gene="rfbD"
                     /locus_tag="IVD66_001721"
     CDS             10902..11753
                     /gene="rfbD"
                     /locus_tag="IVD66_001721"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HAP6145944.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            11787..13820
                     /locus_tag="IVD66_001722"
     CDS             11787..13820
                     /locus_tag="IVD66_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145945.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            13864..15143
                     /locus_tag="IVD66_001723"
                     /pseudo
     CDS             13864..15143
                     /locus_tag="IVD66_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
     gene            15353..16159
                     /locus_tag="IVD66_001724"
     CDS             15353..16159
                     /locus_tag="IVD66_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6145946.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            16171..17391
                     /locus_tag="IVD66_001725"
     CDS             16171..17391
                     /locus_tag="IVD66_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6145947.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            17381..18967
                     /locus_tag="IVD66_001726"
     CDS             17381..18967
                     /locus_tag="IVD66_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP6145948.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            19006..21144
                     /locus_tag="IVD66_001727"
     CDS             19006..21144
                     /locus_tag="IVD66_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP6145949.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(21512..22495)
                     /locus_tag="IVD66_001728"
     CDS             complement(21512..22495)
                     /locus_tag="IVD66_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HAP6145950.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
BASE COUNT         7176 a         3899 c         4711 g         7069 t
ORIGIN      
        1 aaaaaacggt ggggttgttt agcgaaataa aggatctaag ccaatagctt agatccttta
       61 ttctatgctt tatattattt tttgcatgtg tgcgaaagta tactcaagcc caatcgccat
      121 ttcggaaaat cggtactgta gagccatctt cacggattcc gtcgatatcc atcttgtcag
      181 atcctaccat gaaatctacg tgggtttgac ttctattcaa tccagcttct gctaattctt
      241 catcggacat ttctgtaccg cctttcacac tgaaggcata agcagaacct agtgctaagt
      301 gattcgatgc gttttcatca aataatgtat tgaaaaagat gatgccagat tgagaaatag
      361 gtgaagggtc aggtacaagt gcgacttctc ctaaacgacg cgcaccttca tctgtatcaa
      421 gcagttttgc taagacatct tctccttgtt cggcagaaaa atcaacaact tttccatctt
      481 taaaagtaaa tttcataccc gagatgatgg tgccagcata actcagtggc tttgtacttg
      541 aaatgtaacc atctactcga tgactgtcag gtgctgtgaa cacttcttcc gtcggcatat
      601 ttgccatgaa tttttctcca cgagcattat agcttccagc gccttcccaa agatggtttt
      661 taggcaatcc gataatgata tctgtaccgg gagcagtata gtgaagggca gaaaattgtt
      721 ctcgattcaa ttcttctgct ttttttgcta atttttcatc atgcttcttc catgctaaga
      781 cagggtcttc ttcatagaca cgagtcgttt tgaaaatctg atcccataat gcctcaactt
      841 gtttttcttc tggcagttct gggaagactt ttgctgccca ttgtttacca gccgcagcca
      901 cgacagtcca actgacttta tttgcttgag ttgccttgcg taaattcatt agtgctttgc
      961 cattcgctga ttgataagac gctactcgat ggctatctac accagcaaat gcatcgggat
     1021 cggcagaaac aacgctgatc ctgcttgctc ctttttcaag ccattcatcc gcttgatcga
     1081 ttttagattg tggtacattc tcaatacgat ccgttgcagc atgtaaaaga aattctcttt
     1141 ggatctggtc gtcagtccat tgaacgataa cctcagcggc tcctagttta taagcttctt
     1201 gtgtgatcaa tcgagcaagg ggtgcctgtt ccacgctgat ctgtaaaaca actgtgtgtc
     1261 ctttttctgt ggctacgcca gtttctgcaa ttaagcgtgc atattttttt agaagttcat
     1321 taaaatcaga taacataata aaaattcctc ctcaccattt tttctggtaa ctattagcat
     1381 gataccattt aattatgatt caaacaatga ggctttaaat aaaaaaagga ggttattttt
     1441 ttaaggttaa gtttcatgat atatgttact acttgctatt tcagcttgtg aagaaaatca
     1501 aaaactaatt ttgcatatca aaaaaaacat gttacaatga aattaatcaa tggtggaagc
     1561 gttataaaaa aattaaggag attaaaaaat atggcaagaa aaaagacgat tactagagaa
     1621 cagattttgg cagctgctta tgaagtagct gccaccgatg gatttacacg atttactgcg
     1681 agaaacatcg cgaacaaaat gaattgttcc acgcaaccga tttatcttga gtttaaaaat
     1741 atggatgact tgagacaagc tctttttgag cagatctatg atcatttaca atatgaagtg
     1801 ttcactgttg agcatacagg gaatacgatt atcgatcttg cttttaatta tatccatttt
     1861 gcaagaagag agaagaagtt gtatcgttca ctgtacttag aagaatatgg tggaggaaaa
     1921 gagatgcaga atttctctta tacttacttt gtgaatacag tgaaacgcga tccagcttat
     1981 gtgaatcttt cagaagagca gatcgaatct ttgtataatg ggacatggat catagctact
     2041 gggatcgcag ctttgatgtc ttcaagcatc atccatccaa ctgatgaaca gattgaaaag
     2101 atgatccaag acagtataga tgctatcttg aaattcaaag aaccaatcga aatcgattga
     2161 atatactcaa aagttccaca aatcagtagg taacaagaga tgtgtcaaaa taaggaaaag
     2221 ttcgtttttc ttacagcgta tgcattttta actcccgaag aactcttcca tgaatgcaat
     2281 gaataaaaga gccatacaga ttgaataaat ctggatggct cttttattgc aagtatatta
     2341 aatttttgcg actagttctt tagcgaaagc ttctaaattt tcgatatctt cttcttcagc
     2401 attcagatcc actttaacat tttcggctcc ttttgatgcg cctgtttttg caaaagcagc
     2461 atcgaaatca tccaccgatt tgcagaattc atcgtaaaaa gtatcaccag atccgcagac
     2521 accgtaaatt tttcccaata gatccaattc ttgcaagtct tcataaaagt ctacgatctc
     2581 atcaggcaga tcgccatcat cgtatgtata agtagctact acgcaaatat ctgcctcctc
     2641 gaattcatct gcatctactt gggtacattc gttgatttcg acttcgatat ccagattttc
     2701 aaatgcttct gcaacaatat cggcgatttc ttcagtgttt cctgtcatgc tagcatatac
     2761 gatttttgct aaagccatga tgtgcctcct cgtttataat tatttaacaa ttatgaatta
     2821 taccaaaaca tcattgaaaa gaaaataaaa cctagagaca cctggggaat gtcatttggc
     2881 taaatgtatg ccgctatgtt aaaatgagag ggatttgtaa aaaggagacg aaaatatgat
     2941 tactttaaaa tcagcacgtg aaattgaaat gatggcagaa tctggagctt tattagcaga
     3001 tgtacataaa aatctgcgtg attttataaa accaggaatc acaagttggg atattgaggt
     3061 atttgtcaga aactatatcg agagtcatgg cggaattgct gcgcaaattg gctttgaagg
     3121 gtatgaatat gcgacttgta tcagtataaa tgatgaaatt tgtcatggat tccctcgtaa
     3181 aaagcctttg aaaaacggtg atttggtaaa agtcgatatg tgtatcgatt tgaaaggcgg
     3241 catttctgat tcttgttggg cctatgtagt tggagaatct acacctgaga tcgaccgatt
     3301 gatggaagta acgaagaaag ctttgtacat cggtattgag caagcacaag tagggaatcg
     3361 gattggtgac atcggtcatg ctatccaaac ttatgtagaa ggcgaaaatc tagcgatcgt
     3421 tcgtgatttt attggtcatg gcgttggtcc tacgattcat gaagaaccag cagttcctca
     3481 ttacggagaa gctggaaaag ggttgcggtt gaaagaaggc atggttatca cgatcgaacc
     3541 tatggttaat accggaactt ggaaaatgaa aatggatcct aacggctgga ctgcgtatac
     3601 aagagacggc ggactttctt gccaatatga acatacattg gctattacta aagatggtcc
     3661 aagaattttg acatcacaag gagaagaagg cacttattga tctatccagt caataggtac
     3721 gggagaggta catgaaagtt tggaacaaaa taaaacaaaa tgaaaatctg atgcgcttta
     3781 ttgagacgac tcaaaagcgc atcactgatt cagaaatgag tacgacctct gtcgtcgttg
     3841 cttattattt actcttgtct ttatttccat tgattattgc ttttggtaat attttaccgt
     3901 ttctccacat cgatcaagag actgtactga cctatttacg agaagtgatt cctgagaccg
     3961 tttaccagtt tatcggtcct gcaatcaaag accttttgac acaaagttca ggaggcttgt
     4021 tatccgtttc tgcattagcg gctttatggt ctgcaagtca aagtatcaat gctttgcaaa
     4081 ttgcgatgaa taaagcgtat ggcgtagaaa atagaaaaaa ttttttgatc gtccgtttct
     4141 tctcactaat tgtcattgtc ttgttcatga ttgctattag tggggtaact atcgttcttg
     4201 ggttgggaca gctgattttg gatgctattc agccaatcgt acaaataccc gtgaacttta
     4261 tcgatcagtt ccaaactttg aagtggccaa tcacattggt agctttattt gtcatcatgt
     4321 tcttgattta tttaattgtc cctaatgctc agttgaagtt gaagacgatc attccgggca
     4381 cgatcttcgc tactgtcggc tggatgctgt tatcacaagt gtttagtatc tatgctaggt
     4441 attttgcaac gaggatcagc ggttatcaga tcataggaag ttttattgta ctcatgcttt
     4501 ggcttaattt tgctgctacg atcatcattt tgggcggaat catcaatgca gttgttcaag
     4561 aatacgtgac gggtcatcaa atcaaaaaac gtcgagatcc aagccgaaaa tggttcaata
     4621 aattgaaaac taaattttct cataaaaaaa agtagaaaca agagttctta ttgtaaattt
     4681 atatcagtaa tttataataa ttatgactct taattaaagt aggtgcccat atgcttgttt
     4741 cttttagtat ggttataaga ttttttctga caattttatt atcactgata ttaacacctg
     4801 tattcaaaat catttcagta caaacaggta tggtcgacaa accaaatgaa agaagaataa
     4861 ataaagttcc aatgccttca gcgggcggac tgcctatctt tatttcattt gttatatcga
     4921 ctttattctt attccgtaaa attatccctc aatcgtatat tgtaccgatc ttgattgctt
     4981 ctttagtaat catagtcaca ggagtgctcg atgataaata tgagctgaca cctaaacaaa
     5041 aaagtatagg gatcttgatt gcttctctta ttatttattt tgtagcagat atacgtattg
     5101 attccttcac gcttcctttt attggatata tccaactagg ctggcttagt tttcccgtaa
     5161 cgattttttg gatcttcggt atcacgaatg cggtcaatct gattgacggt ttggatgggc
     5221 tggcggcagg gatttcattg atcggtttaa ttacgatagg aatcattgga tattttttcc
     5281 tccatgcttc tacagtgtat attccagttg ttattttctg tcttgtagca agtattatcg
     5341 gtttttttcc ttacaatttt tatccggcaa agatttattt aggcgataca ggagctctat
     5401 tcctagggtt tatgatggcc gtcctttcac tacaagggct gaagaacgtg acttttgttt
     5461 catcgatttc tttgctgatc gtcatgggag tgccggtaac agacacgttt tttgctatca
     5521 ttaggagaaa agcaaaccgt gtttcttttt ctacagcaga taaaaaacat cttcatcacc
     5581 gactaatcag tttaggcttt actcataaag gtgctgtcct gacgatttat gcgatggctt
     5641 tgatgttttc tttcacagct atggtcatga attatactgg aagaatcgga acgatcatat
     5701 tgattattgc catgttgttt gctgcaattt tattatttga attgattggt ctgatcaatg
     5761 agaaacatca gtttatttta aaaacattgc gatttttagg gaataaagag taccgtacgc
     5821 aagtaaaaca gaaatatttg aagaaatgga accgtcatat agatgaataa caaattaaac
     5881 cagccgatcc ttattagtat tgtgacggca aacagtgata aaatttttcg gacactagat
     5941 aattttattt caactgtaaa agatgaaaca gcagtaaaaa tccgaatttt tgacaacaat
     6001 tcacttcccg agtacaaaaa aagactaaca gagtatagga aatatcccta catcgatatc
     6061 tattttcatg atgaaaattc cggatttggt tatggacata atcacaatct gatagctagc
     6121 gattctcgct atggcattat ttgtaaccca gatattttag tggatgaaga gacagttaca
     6181 gcattggtct tgttattgaa agaacatccg gaatgtgcga tgttagcacc taagattctt
     6241 aatgaagatg gaacaactca gcacctcatc cgtgagcagc tggctgtttt tgattacgtt
     6301 ttgcgctttg tgcctttcaa atgggtcaaa aaaaagtttg acaaacgact ggctgtgttt
     6361 gaatgccgag gattgcctac tgatgctaat agttatgtac ggatgatctc aggtagtttt
     6421 atggtagctg atattgataa atttaaagag ataaaggggt ttgatgagcg tttcttcatg
     6481 tactttgaag acaacgactt gtgtttgagt tttgaaaaag caggttacaa gttattgtac
     6541 acaccctttt atgcagttat ccatttttac gggaagggtg cgcatcgaaa tgcaaaactg
     6601 tttcgcgtgt ttttgacttc tatgatgaaa tttttcaata agtgggggtg gcgttttttc
     6661 tgatgaaacc agaaatatta gtagtcgttg tgctttatca gcaactattc agtcaatctc
     6721 cagcttatgg accattaagc aaagcactta gcgaaaagca aattcagctt attatttacg
     6781 ataatagtcc tcaaaggcag caaaatgagc tgtttgaaaa agaaaatatc gtttatcatc
     6841 atgatccgca aaatcctggt ttagcggtgg cttataattt tgcgttgtct caagcagatg
     6901 aaggaacacg ttgtctcgtc actctggatc aggatacgag gctagtcgac gattattttg
     6961 aactattgcg taaagtaacc tttacagatg aatgtgttgc tgcagttccg atgatttttt
     7021 ctgggagccg acaagtttct cccctatatt cagatcgtta tatcaatcgt acagctcaag
     7081 cagtagaagt tgaaggccca acagctgaac gaatcatggc aatcaattca ggtgttgcct
     7141 ggtctgtcaa atttctaaaa aagattggcg ggtttaatcc tgctttttct ttagattttt
     7201 tggatcattg gctgttttgg aaagtggatc agttggaaaa aactgtggag atccttcctg
     7261 tacgaatgga acatgatctt tcggttttag actatgaaaa agtttcaagt aatcgatacc
     7321 gttctatttt acaagcagaa aatcgatttt atcatgaata tgatcaaagg catttatcca
     7381 gtcaccgacg acaattattg ttaagaacag ctaaacagtt cttgaccgtc aaaaaccggc
     7441 atatctggcg gatgactttg cgctcatatg ttaagaattg gaaggtgtga attcgtgcgt
     7501 tcggtttgta tagctacctt taatggaggc agatatttaa gagagcagtt agatagtatt
     7561 ttatctcagc tttcagcaga agatgaagta gtcatttctg atgatgggtc agtagatgat
     7621 acatgggata tattaactga atacgcagaa aaagataagc gaatccagct tttttcgggg
     7681 cctcgtcaag gattgatcgc taattttggt tatgcgatcc agcagacgaa aggagatcta
     7741 atctttttgg cagaccaaga tgatgtttgg ttggagacaa aagtgaaaaa gatcactgac
     7801 tattttgagc agaatccgga tcagctagta gtagtttctg atttaatcat tgtggacagc
     7861 gagctgcaag agatccatga ttcgtatttt tcgtttcgaa attccaaaga aggatggctt
     7921 aataatgtga taagaagtca ctatattggt gctggtatgg ctttccggtc ttctttaaaa
     7981 cccgatattt tgccgatccc gtcagaagtg ccgatgcatg atatgtggat tggtttgctg
     8041 ggaggaaaga agactgggtt cctaagagaa ccgttaactc tgtaccgaag acatgattta
     8101 aacgcgagtg agattgaaac acattctaaa ttacggcaaa aaatttcttg gcgtgttcat
     8161 ctgattacgg cgttgatcaa acgaaaatgg tttaaacgtt gataaaagat gtttaaatcc
     8221 ttaatatttc catgacaaat ataacaattg atgagataat aacaaagtga aatttgaaat
     8281 caaaaaggag agcagatatc catgaaggga atcattcttg ctgggggcag cggaacacgt
     8341 ctgtaccctt taacaaaggc aacatcgaaa caattgatgc cgatttatga caaaccaatg
     8401 atttattatc caatgtctac tctgatgttg gcgggaatca aagaaattct gattatttca
     8461 acgccacaag atacaccacg tttcaaggaa ttatttggaa acggaaatga tttaggactg
     8521 cagatcgaat atgcagtaca agaaagtcca gatggattgg cacaagcgtt tatcattgga
     8581 gaagaattta ttggagatga tagtgtctgc ttggtattag gggacaatat ttactatggt
     8641 ggcggtctgt ctaaaatgtt gcaacgagca gcttcaaaag atacaggcgc gacagtattt
     8701 ggctatcatg tcaatgatcc agaacgcttt ggtgtagtag aatttgatga gaatatgcaa
     8761 gctttgtcga ttgaagaaaa gcctgctcag ccaaaatcaa attacgctgt aactggcctt
     8821 tatttttatg acaatgaggt aatttctatc gctaaaggta tcaaaccttc agaacgtgga
     8881 gaactagaga ttacggatgt caataaagca tatttggata aaggaaaact atccgtagaa
     8941 cttatgggac gcggatttgc ttggcttgat acaggaacac atgaatcatt gcttgaagca
     9001 tctaccttta tcgaaacaat tgaaaaacgt cagaacttaa aagtggcttg tttggaagaa
     9061 attgcttacc gtatgggcta catcgataag gaacaattgc tggcccttgc acagccattg
     9121 aaaaaaaatc aatacggtca atatttattg aatttggccg ctgaataagg agtccttaca
     9181 gatgaaagta acagatacaa aattaacaga tgtcaaaatc gtagaaatgg acgtctttgg
     9241 cgatcatcgc ggtttcttca cagaaagtta ttcaaaagca aaatttgcag aacatggatt
     9301 gaaatatgac tttgttcaag acaaccattc actatcagct gaagctggtg tccttcgggg
     9361 gcttcatttc caaaaaggag aagctgcaca gacaaaattg attcgggtag tcactggagc
     9421 agttttagat gtagtagtgg atatccgcaa aggtagcccg acttatggtc aatgggacgg
     9481 atttatctta tctgaacata atcatcgaca gttgcttgta cctaaaggat atgcccatgg
     9541 attcgttact ttgacaccaa atgtgaactt cctttataag tgtgataatt actataatgc
     9601 agaagcagat gggggcatcg catttgatga tccagattta gcgattgatt ggccaattga
     9661 tccatcaaga gcgattatgt cggaaaaaga tcaccgtcat ccgacattaa aagaatttga
     9721 agcagaaaat ccatttgttt acggagaaat ctaagaatta aggagaaatt ttcttatgaa
     9781 aaacatcatt gttaccggag gtgccggatt catcggctct aatttcgttc attacgtggt
     9841 aaacaatcat ccagaagtgc atgtcactgt tttggataaa ctgacttatg caggaaacaa
     9901 agagaacttg gctggacttc ctagcgatcg cgtagaattg gtcgtaggag atgttgcaga
     9961 tgcagaatta gtggaccgtc tagtaaaaga agcggacgca gttgttcatt acgcggcaga
    10021 atcccataac gataattcat taaaagatcc tttcccattt gtacaaacga atatcattgg
    10081 tacgtataca cttttagaag cttgccgcaa gtatgatgta cgctatcatc acgtatctac
    10141 tgacgaggtt tacggcgatc ttccattacg tgaagacctg ccaggacatg gggaaggcga
    10201 aggagaaaaa ttcactgcgg aaacaccata taatccttca agtccatatt cttctacaaa
    10261 agctggttca gatctgttag taaaagcatg ggtgcgttct tttggcttac gtgcaaccat
    10321 ttcaaactgt tcaaacaact atggtcctta tcagcatatt gaaaaattta ttcctcgcca
    10381 agtaacgaat atcttaagcg gtattcgtcc aaaattatat ggcgaaggaa agaatgttcg
    10441 tgactggatc catacgaatg atcattcttc agcagtgtgg ctgattttga cgaaaggcag
    10501 aattggcgaa acctatctga tcggtgcaga cggtgaagaa gataataaga ccgtgatgga
    10561 attgatctta gaaatgatgg gtcaaccaaa agatgcgtac gaccatgtaa acgaccgtgc
    10621 aggacacgac ttgcgttatg caatcgattc gacaaaatta cgggaagagt taggatggaa
    10681 gcctgagttt acgaacttcc gtgatgggtt ggctgacacg atcaaatggt acgaagaaca
    10741 tgaagactgg tggaaaaaag aaaaagaggc cgttgaagca gcatatgcca aaaatggaca
    10801 ataatacaga gaaaatgtca ctgtattaat ggaaaaacac atgtgaggca ggcgctcgcc
    10861 tgtctctttt ttaaaataaa aatcaaggag cggataatca tatgttttta ttaactggag
    10921 gaaatgggca actaggtaca gaattgcgcc atttattaga tgaaaaaaat ctgcaatatg
    10981 tttcaacaga tgcaaaagac ttggatatca cagatgccga gaaaacaatg gcttacatca
    11041 cagaattaaa acctgatgtt attttccatt gtgcagctta cacagcagta gataaagcag
    11101 aagaagaagc aaaagaatta gatgagaaga tcaatgttga tggtacaaga aatgtagcac
    11161 ttgcagcaaa agctgtgaat gctcaattcg tctatatcag tacagactat gttttcgatg
    11221 gaaaaaacaa aaatgtagaa tacgaagtag acgaccaaac gaatccacta aatgaatatg
    11281 gtcgtacgaa attattaggc gaaaaagcag tagaagagat tttagaagac tattatatca
    11341 tacgaacttc ttgggttttc gggatctatg gacacaattt cgtcttcacg atgcaacgcc
    11401 tagcggaaac ccgcgacaaa ctgactgtag taaatgacca gtttgggcga ccaacttgga
    11461 cacgtacttt ggcagaattt atggtatatg tcatcgaaga aaaagcacca tttggtattt
    11521 atcatttgtc gaacgaaaat agctgttctt ggtatgaatt cgcaaaagaa atattgaaag
    11581 atacagatgt agaagttgca cctgttacgt cagaagaatt tccgcaaaaa gcaacacgtc
    11641 cgcagtattc agtcatgagc ctgaaaaaga cagaagagtt aggatttgtc ataccaactt
    11701 ggcaagaagc acttgcgcaa atgctggaag ctgccaaaaa aatgaataag taatttcctt
    11761 ttatcaaata gaatttggag catgatatgg aaaaacaaac aagaagtgca cgacgaaaag
    11821 aaaagccaaa agcgaaccag gcagattcga atttggtgct tgacctgttt ctaaaactcc
    11881 gctatcttat tggcgtttta gtcatcgtgg tcatcgttac ttttaattta aacggaagtt
    11941 cacttggtgt ttgggataaa tatgtgtcgc aaagagacga tgggaaaaaa actgatgtga
    12001 tttttggaca gaatcgggaa gtgcggtcag acgaatggct ggtgcagaca cctttttacc
    12061 tctcacaagc tgaagaggac tttccgttgg tgaacgagga ttattcatta aacggacaaa
    12121 acatgatcat tgcgtataat tctcctgtaa aggatattac ggttatcgga aaaccattca
    12181 actggggatt ctttttcctc ggaagagatc gaggactttc cttttattgg gcgatgaaat
    12241 tagtcgtcat ggtcttgctt ggattcgaag tactgatgat attaacgaag agaaaaaaag
    12301 ctctatcgct aatcggtgca tttgcgctga cattttctcc agcagtccag tggtggttca
    12361 tgcaacatgt gggcgatttg attttcttta ctttgggact gatgactgct ttttatcatt
    12421 atttctacaa tcatgataaa aaatggctac gaacgttgat gatgcttttg gtggttattt
    12481 tcggtattgg gtttatttta gtgatttacc cagcccatca agtgatgctg gcgtacttgc
    12541 tgatttttta ttttgttggc ctgcttattt actatagcaa gaaagtttca tgggatctgt
    12601 tggatgtagt gttgattgga ggggcagttt tatttattgg cggagtcatg gttcatttct
    12661 ggctaacgtc aaaagacgca ttgttagctt ctttgaatac cttatatcca ggaaaacggg
    12721 taagtactgg aggaaagtgg acgattggcg aatttttttc tttccttaca aattggaaaa
    12781 ttccttttga agatatcaac tattcgaata actctgaagt ggccctgttc tatcactttt
    12841 ttccaactgt attcctagca agtccatttg tgttatttgg caaaaaagat agcgaacaaa
    12901 agttactggg acgtattttg atgatttttt gtctgttttc tatcttttgg attaccgttg
    12961 ggttgccaaa atggctagca gaaatcactc tgctgtctta tgttcctcca ttaagagcca
    13021 tccttacttt tagttttgcg gcttgtttat tatcgatctg gtttatcgct tatatttgga
    13081 gagaagatgt tattcctatt tggtataaat tcattttgtt ggcagtaaat gcatggtctt
    13141 atttctatgc gattacgcat tcgaaaatgg ataattattt ttcggatttt gaaaccatcg
    13201 cagttgctgt gttgggaaca gtgattttag cttttgcatt atttggctgg agacgcttgt
    13261 tttacctcgc ttttgccgcc ttagttatcg tatctggctt tttcgtcaat ccagtcgtag
    13321 aaggtacagg agcgattttt gaaaaaacac tggcaaaaga aatccaaaaa atcgatcaac
    13381 aagatcctgg taaagtttgg ttgtctgaag atgaattata taacttcacc ccaacattgg
    13441 gagtgaaatc cttcaataca gtacgctttt atccagatat agctgcatgg aagaaaatcg
    13501 atccgaaaga agaatacgag aagtattata atcggtatgc tcatacaaga gcttttatcg
    13561 ctaaggaaga tacaaagttc attttagatc gtccagatat gttttcggtc acgttgaatt
    13621 ttgaagacgc agaaaaatta gggatcgact atgtgatcag taaacgacca ttaactgatt
    13681 acaaccaatt atatgaagcg cagttcacgc agctatatgg accggataaa gacggttata
    13741 tgatttttaa agtagaatat ccggattatc cagatgtacc acaaacacaa actcaggaaa
    13801 atcagctagt cgtacagtaa taggctagct gagaataatc ctgaaatgtt agtagaaagg
    13861 agagtggaga taattcaagc aatcgtacaa aaatttgtca acaaaatgag tgtcggtttc
    13921 ttgcttttgt tactgacgct agtctttttt gtttggacag cagggttagg ttttccagca
    13981 actttgttta tatataacaa tagttcatta cttatcgctt ttagtgtggc tattttgctc
    14041 attttaaatg tttataaagc aaaaggcgtc gattttcttt atctaggtgt tgcgcttgcc
    14101 cttttcattt tcttttctta ctttcgggaa ttaagaaatg agtctttatt tggagactta
    14161 ctgtttcctt tgattatttt attttgttta gtaattaaat ggatcgagtg gacaaaatgg
    14221 gatcgcggta tttatctgat tgtcttttcg gtcttcctcg gaatcacgtt tatcgtgtat
    14281 ttacagagat ccaagtacca gaaggacaaa gcatctgggc tccaggcaat tcgctttctg
    14341 atatttggat caatacgaat acaatcggaa gttctttgat gactcttgct ttattgatca
    14401 gtggatttgc cagttctttt gaacgatggt atgtacgaat catcggtgca gtagcagttg
    14461 ttgcagcttt tctcgggatt tgggtctgcc aatctagagg tgcattagtc gcgttgattg
    14521 tttttgcgat attggatctt ttacctaaat cgttgatgcg tgtcattcgt gcgccattta
    14581 ttgcttacac ggttacgatt cttttagctt tgccgatttc ttatctggcg gctgtctctg
    14641 aaaaagtcaa tttgtttacc ggtcgagaag atatttggca taaattctat cagacgctag
    14701 gagaaaaatc tgaacaaatt ttactaggaa tgaaaacatt tatcttccaa cgaggaaacc
    14761 aatttttagg aaaccacaat agttataatt ctattttgaa tatctatgga ttgataggat
    14821 ttgggattgc tgctttgctg cttatccttt ttattggtcg cttaacgttg aaagcagatt
    14881 tatccaacgg gcagatgact tttatctggg ccttttttgc ggtgatgatg cagtcattta
    14941 tggaggatac attgacttca taaccatggg ttccgattat ttatatcctg ttggctatgg
    15001 ccgttcatcg atatgatgaa ccagaagttg cggaggaatt ctatgttatg gaagaggcat
    15061 atgacgatat gacttatgat gatacatctt atgaggaaca accagatagc gctcattctt
    15121 ccaggatcca acgctatcat tgataggcac aaaatacgag agaggctgtg acaaccgtcg
    15181 cagccttttt tggtttattg caattgtcta gcatcttctg taaaatagaa acgttagaga
    15241 aaatcttgta tcatagaaaa ttaagaaaga aataagaacg cagctcggta ccaaaaatat
    15301 ggtaaaatgg cacttgactg taattcactg aaaatcgctt ggaggaacac aaatgtttaa
    15361 agatttgtat ttatttatga aggacattta tcagaacaga aaattattgc tacagttttc
    15421 gatcaatgac ttcaaatcaa gatatgcagg atcgttttta ggaatcttat gggcgtttat
    15481 caatccgcta tttactgtat tgatttattg gctggtattt ggtgttggac tgaaagcaca
    15541 aatgatcgat gcaaaatacc catttatcgt atatttagtt accgggatga ttccctggtt
    15601 cttcttctca gatgcatttg catcaactac ggttgttttt cgggaatata cttatttagt
    15661 aaagaaagtc gtattcaata ttcgtatctt gcccacgacg aaaatcctat ccaatctgta
    15721 cacccattta ttcttcattc tgattggcat agctgtcgcg cttataaatg gtatatatcc
    15781 ttcagcaatg tctttacagc tgatttatta tttattttgc atgtgtgctt tcttgacagg
    15841 attgacttgg ctgacggcat cgatccaacc atttttacct gatatcatgc aattaattac
    15901 gatcgtgctg cagttgatca tgtggacatt accgatatta tggagcccta atcagtttga
    15961 ttcaggtctt gtaagcatat tgaaattaaa tccgctgtac tatgttgttc aaggttatcg
    16021 tgagtcattt ttaagtgaag cttggttctg ggagcatgga acatatactt tgtatttctg
    16081 ggttttcacg ttagtaatgt tcgtaatcgg ctctgcagtg ttccgtagat tgaaaccaca
    16141 tttttcagat gtgctgtaag gagaatagct atgacagaat atgcaattag actaaaagat
    16201 atcacaaaat cttataatat gtacgcaaaa ccttcggatc gatttcgtga agccctcaat
    16261 ccttttaaga aatcctatca tgatgtattt tatgcgttga aaaacgtgaa tgtagaaata
    16321 aaaaaaggtg agatgatcgg tttcgtggga gaaaacggat cgggaaaatc tacaatgttg
    16381 aaaatcatta cgggagtact gacaccaaca tccggcacga tggaaatcga aggaaaaatc
    16441 tcagctttgc tagaactagg atcaggattc aatcctgagt attctggcta tgaaaatatc
    16501 tatttaaatg gaatggttct aggattttca agagaagaag tcgatgaaat ggtcgatgat
    16561 atcattgaat ttgctgacat cggagaccat atttatcaac ctgtaaaaac ttattcaagc
    16621 gggatgttcg ttcgtctagc ttttgctgta gcaatcaatg tgaatcccga tattttgatt
    16681 gtggatgaag cattggcagt aggcgatctt gaatttcaac taaaatgtat ggaaaaattt
    16741 acagaaatca agaactcggg aaagacgatt ttattcgttt ctcatgatat cagttcgatt
    16801 cgtcgttttt gtgatcgttc ctattggttg aaaaacggag aagtcgtcga atatggcgat
    16861 acgatggaag taacgacgaa ttatgaaaac tttttaaaga aaaaatcagt taaaacagtg
    16921 gatcggaata aaaaccaagt agaacggttc gccgctccag atatcgtcga cgtgacgaaa
    16981 gcggaattgt tggataaaga caaaaatccg gtggatatgc tggaacaagg agaaaaacta
    17041 tacgttaaag taacttatga agtaaaagat gatacaatca aaaatccggt tttaggaatt
    17101 gcgctacgaa cagtcgacaa tttttatgta tgcggactta atactctact agatggtatc
    17161 aagattcctt ggaaaaaagg agagaatatc ttttatctgg agtatgaaaa gttaggtttg
    17221 ttagctggtg aatattattt tgacgttgcg gtctttgaag aaaatgcaac ggttcctttg
    17281 gtatataaga caaagtacat gaacttgttt gtcagcggtt cttatatcgg agaaggcatc
    17341 gtggtcttag accataaatg ggaagaaggg actcatagca atgaaatatg attttgaaat
    17401 ggacctagat gaacaaagca gtgtgggaaa aattgccgca cagatcaaac caggaagtaa
    17461 agttttagag tttggtcccg gaaacggccg attaacgaaa catttaatcg gagcaaaaca
    17521 atgtgaagtg agcattgttg agttagataa ggaattgttc gattttgtca gcgaatttgc
    17581 tcaagatgga ttttatggtg atatcgaaag ttttgagtgg gcaaactatt atgctggaca
    17641 gacatttgat tacgtcttgt ttgcggatgt tttagaacat ttggtagatc ctggaaaaac
    17701 attgaagaaa gtcagagaat ttttgaatga agaaggagag atcctgatta cattccctaa
    17761 cttggcgcat aattctgtca tgatcgattt gttcaataac caattgccgt gggcttctta
    17821 tggtctccta gatgaaaccc ataattcttt ttatactcat gatggcttcc aaaaagtttt
    17881 tgaaaaagcg ggattattca ttaatattga agattatttg tacttagctg taggtgatac
    17941 agaattaaaa tcaacttatg aagaattgcc ggaagctgta cgctatgatt tcaaaatgcg
    18001 accatttggt gaagtctacc aatacttttt ctcattgatg aaacatccag tagcacaaag
    18061 ttccattgca gagccacaaa attctaatta tgtaaaagtg ttagaagtaa cccagcaaac
    18121 gaaacaagat gaaacaatcc aacaaatacc attcaataat ttcacagggg aaaatgagac
    18181 actaagtttc cccgtatcag aaacaacaga aagaatggtg tttcgcttcg cgcaacaacc
    18241 tagctttatc gaattcagcg cagaagctgc cggagaaaaa ctaacattta tcgattcgaa
    18301 tgctgtagtc aaaacagtaa atgattgtta tttgtttgat gggaaagaat taccagagtt
    18361 cgttctaacg gatatttctg ggaaagaagt gactatccat tgtcactatc gctttatcgg
    18421 ggaattgaca ccaacaatga aagaattgtt ggaaacgatt cgtcccatgg ctgaagtcac
    18481 aaagcagctt tctgagaaaa atgacgaatt agaaagagaa aatcatcatc ttcttgagga
    18541 aaatacaaga ctagaccata cgttaaaaac aaccacaaat cgctattgca cattgttgga
    18601 aagtgatgaa tggacaataa aacatagact aggacgacgt aagaaagaaa cttcgaaaaa
    18661 aatccaagaa aaagaacttt ctatatgtat tgacgagaaa atctgggatg cagaaacaaa
    18721 aatattaaaa atcatcggat ggggaatcgc taattcggat cgccagccct tgtcctataa
    18781 gttatcagct gaccaatcgc catttttcga agcaattcct gtttcacgag aagaagtcaa
    18841 tcaagcagaa cagctcgcaa aaggaacaga agcgggattt gagttacgaa tcctttgcga
    18901 gcaagaacgt tcattcttag tggaagcagt agctcaaaat ggccaatcat ggatcattga
    18961 aatgtaaata atgattaact tataaagata aggagtaaac gaatcgtgca aaaaaaagaa
    19021 attgccgtat ttatcgatca aatcactcgt gaacgggcca ctggcgattt gcttattgtg
    19081 ggctgggcaa ttgatgaagt gaccaaagaa atccctacga taaaggtaga aaaagaaaat
    19141 gtgattgctg aagcaacaca tgtcgtaaga ttggatatca atcatttata taatcttgat
    19201 gttaagaccc aaagcggttt taaggtacgt ttatcaggga aaatgagagg aaaagccatc
    19261 ttagacttcc aaacagcgag acatcaaaat ggcatagctg tgaaattaaa cggtaaatac
    19321 ccttatgatg acggcattga atcttcatgg gaaagaaaaa aaagattact gaaaaaaggg
    19381 ataaattatg caaggactca tggcgtaaaa aaagcgatcc gtcgggtcaa attggaattg
    19441 aagccaggat cgatcgacta tgcagagtgg atcagtcgtc atgagaaacc agatttgaaa
    19501 gagcaaagga aagaagcaca aggatttgcg taccgtccat tgatttccat acttatgcct
    19561 gtctataacg ttgaaatcaa atggctcgaa aaatgcattg attcggtact ggatcaaacg
    19621 tatgatcatt gggaactatg tatcagtgat gatgcttcta ctgatccagc tatccgaaag
    19681 tgtctggaat cctatcaagc aaaagatgat agaatcaaag tcgttttccg aaaagaaaat
    19741 ggacacatca gtctggcaac taattctgca ttggaaatag cagaaggaga atttatagca
    19801 ctcttagata atgatgatga attaccgcca tttgcattat atgaagtggc aaaagtgcta
    19861 aacgtacatc cagaactgga tgtgatctac agtgacgaag ataaaatcga tgcagatggc
    19921 aatcgctttg atccgcattt caaagcagac tggtcgcctg atacattgat gggaaataat
    19981 tatatctctc acttaggcgt atatcgaaca agcattgtta aagaacttgg cggtttccgt
    20041 aaaggctatg aaggttctca agattatgat ttggtccttc gtgtgacaga acaaatccct
    20101 gcagatcata tttaccacat tgaccgagtc ttgtatcatt ggcggacgat cccaggatca
    20161 actgcaagta atggcgaagc caaaagttat atctatgatt ccggagtgaa agcattgaca
    20221 gatgccctgt ctagaagaaa catcaaagga agcgtacgtc ctggcagaat ttctggattt
    20281 tatgagattg cttatgacgt cttgcaagag gatttggtca gtgtgatcat tccaacgaag
    20341 aatggctatg aagatctaaa aacttgtgtg gattcgatca tcgaaaaaac gtcttattca
    20401 aattatgaaa tcattattgc ggataacgga agtacagatc caaaaatgca agaattattt
    20461 gcagaataca agcatcagct gaaagaccgc tttatcgtag aattgattga cattccattc
    20521 aattattctc gaattaacaa tttagcagca gaaaaagcaa acggcaaata ctttttattc
    20581 ttgaataacg atacagaagt gattgagcca gattggatga cggtgatggt ttcttatgca
    20641 cagtttgatc gaatcggctg tgtaggagca aaactgtttt atccagatga tacaacgcag
    20701 catgcaggag tattattagg aatcggtggt gttgcagggc atgcattgaa taactatgat
    20761 cgaacacatt gtggttattt cggccgattg gtcattgacg tcaattactt agcagtcact
    20821 gcagcttgta tgatggtcaa ggcagctgac ttcaatgctg ttaacgggtt tgatgaaaca
    20881 ttagaagtag cattcaacga tgttgacttg tgcttgaaag tttatgaact gggtcgttac
    20941 aatgtctatg cacatcaagc agaattgtac catttcgaat ctaaatcaag aggttatgaa
    21001 gatactccag aaaaacaaag acgttttgct ggtgaaatca aaaaaatgca agataaatgg
    21061 ccagcatata ttgcgcatga tccattttac aatgataatt taacaaaaga aggaatcggc
    21121 gacttttcgt tgagaccaga ttaaactata ataaaaagct gttatgttgt gattcgctcg
    21181 cacataacgg ctttttatag ttttttgtca aaaaaaggca gaaggtgccg actcaaaaaa
    21241 ataagtcgag gttgggacag aagtgtttaa ctccgagaaa taagaagaaa ttcacgaaaa
    21301 ttgcttttca aatttttgtg aatttcggct tatttaagaa gaagttgctt ctgctcccac
    21361 cgtttattcg tttttaaaga atgagacaaa agtgtttctt acttttgtcc cacgctctta
    21421 ttcatgctca gagcgccaat agatacaaaa tcatagccaa agtttcacga accctagctg
    21481 tcaaagaatc gatattttat tttaatatag gctattttaa aataaatggt ttaaggtatt
    21541 cctctacaaa agccactcta tcaattatca tgggtttaaa ataagaagtg atggagataa
    21601 ccagattgtt cttagcgtca atataaagaa catttccact attaccaatt gctgaatata
    21661 tttcgttctc agaatctaat acccaccata aatagccata tctcatattt tgtaagtctt
    21721 ctaaagcact ggttctaggt ttgaacatct cgtttatcca catgggtggt acgatttgtt
    21781 ttcctttata catcccttta tttaggcata atacaccaat ttttgccaga tcacttgccg
    21841 ataaacacaa accatatcct gccgtcccga tatttagtgg atcacaaaac cagacattgg
    21901 ttttaggaga cttatccatt gtaaactgct tatgttcttc agctgtttca gcataataat
    21961 tgacatggtt tggtatccct ataggatcaa atagatactt attggcaaaa tcaacagttg
    22021 ttagcttact tgtctgatac aacaagccag ttaatatgtg taaacagaca gtttgatagt
    22081 tgaattcgcc ggttatacct tttcttcctc ccaataaatc tagtgatgtt tttgtccaat
    22141 cttcacttga acagactttt gtccatggat cgcctttaca tttgtagggt gctttcattg
    22201 ttagcaagtg cttgattgta atagcgtaaa tagttttctc cccgcgtttc actttatact
    22261 ctggaaaata atctaatact ttatcatcga tacttttgat taatccttgc tctaaagcaa
    22321 tgccaatcag caaagataca atacttttcg ttgctgacat gatatgacaa gtatcgtctt
    22381 ttttataacc attccattca tctgtataaa cttctacccc atccttatat gcgacaattt
    22441 gacatatatt tggttgtcga aaaccaataa aatcatgcaa ctcttgttta ttcataagat
    22501 attacctcac tttcttctat aagcataatg tcattaaaaa tcgatttcaa ttttttcgat
    22561 tcttcacgta atacaggtat tcttatggac tagacagcgc tttgggaaga tggattctct
    22621 gaaaaatata aaggttcact ttatgagtgg ataaaaaaag cagcaaatac ttcgacttct
    22681 ttaatttacc aacattagtg aaaatcgatt catctggaga tttgtaattt agagtccttg
    22741 tcttgattag aggtgtataa agctttttat tagacatttt taaattccat tacaatttgc
    22801 ttataaacta ggtttttaaa ggtgactatg gtaagataat agagatatta ttttg
//
LOCUS       DACBZK010000043        22132 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.044, whole genome shotgun sequence.
ACCESSION   DACBZK010000043 DACBZK010000000
VERSION     DACBZK010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22132
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.044"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..523
                     /locus_tag="IVD66_001729"
     CDS             <1..523
                     /locus_tag="IVD66_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HAP6145951.1"
                     /translation="GGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGIVA
                     NCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIFGS
                     LIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILTVL
                     LLPLFFQPFAGLF"
     gene            523..2109
                     /locus_tag="IVD66_001730"
     CDS             523..2109
                     /locus_tag="IVD66_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP6145952.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            2128..2349
                     /locus_tag="IVD66_001731"
     CDS             2128..2349
                     /locus_tag="IVD66_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HAP6145953.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            2346..3107
                     /locus_tag="IVD66_001732"
     CDS             2346..3107
                     /locus_tag="IVD66_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HAP6145954.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            3487..3996
                     /locus_tag="IVD66_001733"
     CDS             3487..3996
                     /locus_tag="IVD66_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAP6145955.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(4071..4610)
                     /locus_tag="IVD66_001734"
     CDS             complement(4071..4610)
                     /locus_tag="IVD66_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HAP6145956.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(4750..5361)
                     /gene="rpsD"
                     /locus_tag="IVD66_001735"
     CDS             complement(4750..5361)
                     /gene="rpsD"
                     /locus_tag="IVD66_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HAP6145957.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            5677..6474
                     /locus_tag="IVD66_001736"
     CDS             5677..6474
                     /locus_tag="IVD66_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-nitrite transporter"
                     /protein_id="HAP6145958.1"
                     /translation="MNPVSPLFEKIDASIEKKANLFENSFSRYAVRAVLACLFLTLGT
                     AVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAELGTSNMLYMTVGVFRQRLA
                     LSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNFMLESIAVKLAKPSATILV
                     EGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLGYEHVIANFPAFTLTYFAS
                     HGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQSKSSYVD"
     gene            6502..7137
                     /locus_tag="IVD66_001737"
     CDS             6502..7137
                     /locus_tag="IVD66_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HAP6145959.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            7157..7930
                     /locus_tag="IVD66_001738"
     CDS             7157..7930
                     /locus_tag="IVD66_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP6145960.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            8338..9135
                     /locus_tag="IVD66_001739"
     CDS             8338..9135
                     /locus_tag="IVD66_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HAP6145961.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            9113..9526
                     /locus_tag="IVD66_001740"
     CDS             9113..9526
                     /locus_tag="IVD66_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145962.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            9510..12155
                     /gene="mutS"
                     /locus_tag="IVD66_001741"
     CDS             9510..12155
                     /gene="mutS"
                     /locus_tag="IVD66_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAP6145963.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            12173..14281
                     /gene="mutL"
                     /locus_tag="IVD66_001742"
     CDS             12173..14281
                     /gene="mutL"
                     /locus_tag="IVD66_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HAP6145964.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            14303..14863
                     /locus_tag="IVD66_001743"
     CDS             14303..14863
                     /locus_tag="IVD66_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HAP6145965.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(14948..16936)
                     /gene="treP"
                     /locus_tag="IVD66_001744"
     CDS             complement(14948..16936)
                     /gene="treP"
                     /locus_tag="IVD66_001744"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HAP6145966.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            17159..17872
                     /gene="treR"
                     /locus_tag="IVD66_001745"
     CDS             17159..17872
                     /gene="treR"
                     /locus_tag="IVD66_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HAP6145967.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            17949..18395
                     /gene="msrB"
                     /locus_tag="IVD66_001746"
     CDS             17949..18395
                     /gene="msrB"
                     /locus_tag="IVD66_001746"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HAP6145968.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            18565..19167
                     /gene="ruvA"
                     /locus_tag="IVD66_001747"
     CDS             18565..19167
                     /gene="ruvA"
                     /locus_tag="IVD66_001747"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HAP6145969.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            19180..20181
                     /gene="ruvB"
                     /locus_tag="IVD66_001748"
     CDS             19180..20181
                     /gene="ruvB"
                     /locus_tag="IVD66_001748"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HAP6145970.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            20210..20788
                     /locus_tag="IVD66_001749"
     CDS             20210..20788
                     /locus_tag="IVD66_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAP6145971.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            20840..21322
                     /locus_tag="IVD66_001750"
     CDS             20840..21322
                     /locus_tag="IVD66_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HAP6145972.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            21439..21813
                     /locus_tag="IVD66_001751"
     CDS             21439..21813
                     /locus_tag="IVD66_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145973.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7237 a         3991 c         4790 g         6114 t
ORIGIN      
        1 cgggggcaat tttttgacta tgctgattac tcctgcgaca gtggcacttg ccatccctct
       61 ttataaaaac ttccgtttac tgaaagagaa tttttatcct gtaatggctg cgattttagc
      121 aggaatagtc gcaaattgct tggttagtgt agggttcggt tacttcttct ctcttcataa
      181 agagatggtg atctcattac tacctaaatc tgtaacgacg gctatttctg tcgatttatc
      241 tcatacgatg ggcggggtga atgccgtgac acttgctatt gttgtctcta caggtatttt
      301 tggttcgctg atcgccactc atattttccg cctattcaag atcgaaagtc cagttgctcg
      361 cggtgtggcg ttaggaagta cttctcatgc tattggtaca gcaaaagcaa tcgagattgg
      421 tgaaatagaa ggaatcattt ccggacttgc gatatgcgtc aacggaatat tgaccgtttt
      481 attgctaccg ttattctttc agccttttgc tggcttgttt tgatgcgaaa accactattt
      541 tatgctacaa taaccaaaac gttcgagcat aaaaaaggag ggaaagacgt gtatttgtct
      601 tccgagtatc ttaaacaatt tgataaagat ctatattata agattctcct cctagaaagt
      661 tttgaggatc aagcttggca taccgctgca caattagcgc aagttgttca gctggatgcc
      721 cgcagcgtgt cgaaatacct gaacgagctg tctaaaaact atcagcagtt tagcggtaag
      781 acacaccctt tgtttacaaa aaatcaccgt tctggttata acttttatga tacgctcgat
      841 tcaattgaac atgagcgttt tttgatctat ctcgtgcaaa gtacgctgaa attccagttg
      901 ctgcacgaca ttttttttga agaattccat acaatgtacc aatttgcgca aaagcattac
      961 attagtgaat ctactgctca tcgaaaaatc aatgaatgga aacagcaact gcaaacttac
     1021 ggaattcggc tgcaacgagg tacatatatc gctcaaggcg aagaagaaat cattcgactt
     1081 tacttgcata tgacattctg gcagttgttt cgagggaaaa tctggccatt tgaaacgatt
     1141 tctcaaatgg acgtaaagaa tatggcagaa catatcatgg ctttttttaa tgttcgtctg
     1201 aacgagatca aaaaaagacg attggaatat atgctaggtg cctttttttt aagaaaatca
     1261 cagaagcatt atgttgtatt gaatgagaaa aaaagacggc tgatttctga caatctgttg
     1321 ttccagcgat tttgccaggt catggagccg gtatttccta attattttca agtagaagac
     1381 gagttaggcg cattatttct tgtactgatg actcgtgaag aatattatag tgatcctaag
     1441 atacggaaga aaatttttga ttttcatcaa caagcaaaaa caccgccctt tacagccctt
     1501 tcagaagcaa aagccgctct ttctctttat caggaagagc aggggctgcc agcagaaaat
     1561 ctaaccttcg aggcagaaaa ctatttattc agcagtcatt ttttcgccta tctttttcct
     1621 aatgcgaaag aaacgattga tggcaatagt agtgatttta ttaatcattt agttattgaa
     1681 aacaaggaat tgaaacaatg gctcgtacat ttttttgaaa gtagacacaa acatcccaat
     1741 catctggcat ttaaaaatca tgcgtttttg atggggcggt atctgactgt gtttaaaaca
     1801 ttaggagcct ttactccaca gcttccaaag atcacgatcc ttttaatgac agatttccca
     1861 ttatttgaag agcaactgtt agaggaggga ttacggacat ttttccgtaa tgagtatcag
     1921 ctgatttttc tgccaacaga ttatcggggg agagaagttg atcttctgat ttcgacaagt
     1981 aaagtccacc gcaaaccatg ggcggatctt gactatttta ttgtgactga agaactaaaa
     2041 ttaattgatt acatccaact atctcaaaaa tttgaaatga ttcaaaaaca aaaactatta
     2101 aaacaataac aaagaaggag aaaaaagatg acatttgaag aaattttacc agaattgaaa
     2161 aaaggtgcaa agattattcg taaaggatgg agtggatttg aactttatgt tgttctcgta
     2221 tccgatgatg aatttgatgg ctgtccggtg acgccgtact tattgatcaa aacaagtgac
     2281 gaaggttttt ccagcttcgc tcctacagtt tgtgatattt tagcagatga ttgggcgatc
     2341 gtagaatgaa aaaccagtat ccagatctag ctaaacaggt tgtatttatc acaggagctg
     2401 cttctggaat tggtgctgcg caagcccgag cgtttcttga acaagatgct tttgtatttg
     2461 gattagatca aaagttcggt aaaatggaag aaatttcttt gcgatttcct gaaacttttg
     2521 cctacgcact aggtgatgtt cgacaaatga aagaactcca acaagcggta tcgaaatgcc
     2581 aaaatcattt tggtgaagtt acgattttac tgaatacagc ggggatattg gatgcctaca
     2641 aacccttgat ggaaactgac gaatcgctgt gggatctgat ttatgagacg aatgtgaaaa
     2701 gcatgtatca gctgacaaaa atcatccttc ctgatatgat ccgccaaaaa agcggaacga
     2761 tcatcaatat ggcttcgatt gctggcttga ttgctggtgg aggtgggatc gcttatacaa
     2821 gcgcgaaaca tgcgattgtc ggatttacca aacaactcgc tctggattac gcaggacagg
     2881 gtatccgagt aaaaggaatt gctccaggag ccatccaaac accaatgaat gcggctgatt
     2941 ttgaagggaa aggtgagatg gcagagtggg tggcaaatga aacaccagtc aagcgatggg
     3001 cacagccgga agaagtagct gagctgacgt tatttcttgc ctctcctcaa gcaagctaca
     3061 tacaaggaac gatcatccca atcgacggcg gatggttgtt aaaataacct tgtgtttttt
     3121 tcaagcttct gtatgataaa actaaagaga gaaacaacgg ttgatgataa aaaaagtcga
     3181 tgactgttcc cgacattcga tgccgaacag ccagttcaaa aaattctttt taataatcgt
     3241 taatattcga aactaagcgg cttttcacga cctcttgata taaacgatat tcaaaagctt
     3301 gcaactgcgg taacaagtcc agccaaatga aaaatataag gagctatttt tatttgacca
     3361 ttcttattac ttgttgcagg gcagcttttt cactaccttc tgcgacactt cagttggaat
     3421 tttcttccca tcctttggtc gcggtcatta ccaagataaa attatcttgc aaaggagaaa
     3481 tagaacatgg aaaaaaataa tacccgttca gccaaacgct ggacaacgac agatgtgact
     3541 cggatggcgc tagtcactgg tttatatgtg gcagtgacgc tggttttgtc tgtctttagc
     3601 tttggagtga ttcagattcg tctctcggag atgttcaact atctgtcctt gtataacaaa
     3661 agatacatcg tcgcggtaac agcgggagta gctttggcta atattgcttc tcctcttgga
     3721 ctgatagatg ttgcagtagg aagcgtcagc acgctgcttg tattgcttat caactataaa
     3781 atcactagtc gcatcaaaaa catgaaaatc aaaatggccg tgacagcatg cgtatttgct
     3841 ttttccatgt ttacagtagc tggtcagcta acgattttat atcaactacc ttttttcttg
     3901 aattggtggg tgattgcttt aggagaattg gcatcaatga ttgtcggtgg gataattatt
     3961 tattggatcg gtaaaaaagt ggatttgtca aaataaagat ctgtttaatt taaaataggg
     4021 cagcatggaa gagactgaat gttgagtctt cttccatgct gcttttttga ttaatttgta
     4081 tgaagaaatc gatttagccg ttttttcatc aagataccga tataagctgc tccagttgcc
     4141 ttgattgctt ccggcagtaa aaacggcagt agtccactgg caaatgcagt tgtaaaagta
     4201 agatcaccac ttattttcag ccagatcgtt ccgcagatca atgcagcaag agagcccatt
     4261 agattggcaa agattgcata taagtaatga gcatccgttc tttcgatcat ccaaccagtt
     4321 atccacgttt gtaagagaaa tccaatcaaa tatccgccag ttggcccaaa taaaacagct
     4381 atacctccag tcatccctga aaatacagga agaccaatca agccaagtaa aagataaact
     4441 ccaacagata tcaatcctag ttttcttccg agaaaagttg ctgttaatcc aatagcaaat
     4501 gtttgccctg tcaaaggaac caaaccaaaa ggaatggtca tctgagaaag gacagaaata
     4561 atcgcggcaa attccgcagc aagtatcaat tctttcaatg ttcggttcat aacgccctct
     4621 tttcgttaac ttaatatttt tatttggtta acgaaattgt aaaacaaagt gattactttg
     4681 taaatagaaa atataaaaaa agaccagcta tccaatagat agcggtcttt ttcaagaaag
     4741 cttttgaaat tataagcttt ggttgtagta ttcaacgaca agagcttcgt cgatttctgg
     4801 atatagttcg tcacgttctg gtaaacgagt caatgaacct tccaattttt cagcgtcaaa
     4861 gcttacgaat gctgggcgtc caacagttgc ttctacagct tcttttactg ttacgatgtt
     4921 ttgtgatttt tcacgaactg agatcacttg acccacttct acgtggtatg aagggatatc
     4981 aacgcgtttg ccatcaacta aaatgtgacc atggttaact aattgacgtg cttgacgacg
     5041 agtcgttgca agtcctaaac ggtaaacaac attgtctaaa cgttgttcta gtaagatcat
     5101 gaagttaaca ccatgtttac cttctttgat tttgctagct tttacgaaca agttacggaa
     5161 ttgacgttcg ttcattccgt acatgtgacg aagtttttgt ttttcagtta attgcatgcc
     5221 gtattctgat tgtttgccac ggctattagg tccatgttga cctggtgcgt aagggcgacg
     5281 tgctaattct tttcctgtgc ctgacaatga gatgcctaag cgacgagaaa ttttccatga
     5341 tggtcctgta taacgagaca ttaaaatttc ctccaatgaa tataagtttt tggagtaaaa
     5401 taatccgttg aaaaattcat aatcatatag tttgttcttc aatcttcacc tttgcagccg
     5461 cggttacaca atcgaacccg agacggggca acaaactagg gatgagttat tatttttctg
     5521 ctgcattatt ttacacaaat tacagtatat gatagatcat ccacgaatgt caagataatt
     5581 agtacataaa aacgctttac aaacctaggc tgtctttata aaatgagagg gtatgtgcaa
     5641 atggaaaaaa gcgaaggaag tttaaggaga aaatcaatga atccggtatc accattattt
     5701 gagaaaatcg atgcttcaat tgaaaagaag gcgaatcttt ttgaaaacag cttttcacgt
     5761 tacgctgttc gagcggttct cgcctgtttg tttttgactt taggaacggc tgtggcattt
     5821 gcgatcgcga tgaaggggga agatatcgcg catggtctag gaaagatttt atacgcattt
     5881 atgttcagct ggggtctggt catgattcta tacatgaacg ccgaattagg aacatcgaat
     5941 atgctttata tgaccgtggg tgtttttcgg cagagacttg ctttaagtaa ggcagccaag
     6001 attctatttg cctgtatttt tttcaatatg attggcggta tattatgtgg atttctaatt
     6061 tctatgacta cgccatttca agatttaacg ttggacaact ttatgttaga atcaatagca
     6121 gtaaaactag caaaaccttc agcaacgatt ttggtggaag ggatgtttgc gaatatcgtt
     6181 gtcaataccg ctgtactgat cagcatgcgg atgaaagagg atgtcggaaa agtgatcaca
     6241 gtcgtattca tcattttcat ttttgctttt ttaggatatg aacacgtgat agcgaatttt
     6301 cctgccttta cgcttactta ctttgcttct cacggacaga tggatggaat gacagtcagc
     6361 aatgtgttac ataatttgtt ttttgctttg gcaggaaatt atattggtgg cggtttagta
     6421 atgggactgg gatatgcttg gctgaatcag tcaaaatcat cctatgtgga ctaaaaagtc
     6481 gttcattaaa ggggaagtgc catggaagtt ttagtttttc caaaaaatga ggaaaaagcg
     6541 ttacaaatgg aaaagtacat gaaaaatctt ttttcctttg ctggagtacc taagccggaa
     6601 cgcgctcttt tacaacaacc gttactggat gagagcaaaa atttatctat ttctgaagtt
     6661 ttagcttttg ttcattatta ttatgaacaa atcgaaagag agtatcagta tgtagcgatc
     6721 gatttagtcc agaaaaacat caaacggctt acatttgaag acttagtcgt attgttgcca
     6781 ctagttcaga aaaaagaatg gtgggacagc atcgactctt ggagaaaagt atacagcaca
     6841 tggtgtaaag cctacccaga gcagcgtgaa gaagtctttc aattgtttga aaaaaaggaa
     6901 gatttttggc tacgtcgaat agcaatcacg ttgcaattag gttataaaca gcaaacagac
     6961 acaggactat tgatccgagc aatagacgaa gatcgtcaaa caaaggaatt ctttatccaa
     7021 aaagcaattg gttgggcatt acgcgattat agtaagaccg atgccgattg ggtaaaaaga
     7081 cagctgacaa cagatttgag taagttagct gttcgagagg caagtaagta tttataagaa
     7141 agcgagacga caagagatga gacgcaaatt atttgctttt gatattgatg gaacgttgtt
     7201 agattcaaac aaacaagctt tagatagcac aagagaagca ttggaaaaat tacgcaaagc
     7261 cggtcatctg gtcacgattg ctacagggcg gagccgattt catgcgcaag agatcattcg
     7321 cgatcttgat tttacgaact acattttatg taatggagcg gccggttttt tagaccatga
     7381 acaagtatat aagaatttac tagatcgcga ccagttggat gcgttcgttc aagaagcgca
     7441 tcatgagcag atcgatacag cttttgtcag cttagacaat atcaagcgtt cttcttccaa
     7501 tgatgtaacg gtgatggaag aagcgatgca ttctttcggt gctgtcttgc ctgaattaga
     7561 tcagtttttt gcagaggaac aagaaatata ccaagcgtta gcatttttcg atcaaacata
     7621 tgatgggaag ttctcttcat atgataaaat tcgatttgtc cgctggcatg agaacagtgt
     7681 agatgtcgta cctaaaaatg gttctaaagc agcgacaatt ctgcacttag cagaacaagt
     7741 aggcatccct catgaagaca tcatcagctt tggcgatgga caaaacgacc gtgaaatgtt
     7801 gcgcatgtca ggaattggga tagctatggg gaatgctgtg ccagaagtac aagcagaagc
     7861 taagatggtc actgatacaa acgatcagga tggaatttgg aaggcattga aagagttaag
     7921 cgtgatttaa aagaggttgt gaaaaagctg ttctgcatca agtaataagc ccagccaaac
     7981 aaaaatagct cctcctattt ttcgtttttc tgggcttatt accgcagatg caagctttcg
     8041 aacaccgttt aaggaagagg tcgtgacaga agtggtcagt ttcaagaaat aagaagggat
     8101 ttacgaaaat tgcttctcaa atttttgtaa aattacggct tatttctgaa gaagtagatg
     8161 aaacaacgtt tattcgggaa atgggactgt gacaagatgt ttgtcatagt cccatttttt
     8221 tattttattt ttcaaaacta agaaatacca ggaaagagtt ccttttgttt gaccttttct
     8281 ttcttattga aaacaactat aatatagagt gatgttaaaa gagaagagga atttagtgtg
     8341 cgggtattgt ttattggtga tgtagtaggt tcaatgggac gagagatgat tactgaatat
     8401 cttcctagat tgaagaagaa gtaccgtccg caagtaacga ttgtaaatgg tgagaatgcc
     8461 gcttctggac gtggaatcac agaaaaaatc tataaaaaat ttttgcaaga cggcgtagat
     8521 gtcgtgacga tggggaatca tacgtgggac aaccgcggaa tctttgagtt tgtaaatgaa
     8581 gctaaaaaga tggttcgtcc ggcaaatttt ccggaaggga cgcctggaca agggatggtc
     8641 tttgtcaaag tgaaccaagt cgaactggca gtgatcaaca tgcaggctcg ttcttttatg
     8701 gtggacttgg atgatccttt tcgtaaaatg aatgagctgg tagaagaagc cagaaaacgt
     8761 acgccgatca tttttgtaga ttttcatgga gaaacaacaa gtgaaaaaca agcaatgggc
     8821 tggtttttag atgggaaagt ttcagcagtg gtcggtacac atacacacgt tcagacaaat
     8881 gatgcgcgaa ttttgccaag aggaacagcg tatctgacag acgttgggat gacaggtccc
     8941 tatgatggta ttttgggtat gcgcagagaa cctgtaatcg aaaagtttct gactgcatta
     9001 ccaaaacgtt ttgaagttgt ggaacaaggc cgatcgattt taagcggctg tatcttggaa
     9061 ttggatgata cgacaggtca tgcaaaagaa atccagctga ttcagatcaa cgatgatcga
     9121 ccgttcatgg agtagaaaga gaggcagttt tttgcagcag gagccggaaa ttcaaaaaga
     9181 agtaaggaaa ctgacaaaac ttttaagaga gaatgaaacg atcattcgct acaaagaact
     9241 tgaagaaaag atccagcaaa accagtattt agctgagttg agagaaaaaa tcaaacaagc
     9301 gcaaaaagat gctgttcatt ttgcccacta tgacaaacca gcagcagaaa aagaagcaat
     9361 caaacaagcg gatcaattca tgcaagaatt tgatcagcat ccgcttgttg tagcttatag
     9421 aaaacagctg ttggaagcag atgatctgct tcatcattta acaactatga tacaagaaga
     9481 aatcaatgga caaatagagg aggaaaaaca tgcctcaaaa aactaaaaat actcctatga
     9541 tggaacaata tctaagcatc aaggcccaat accaagatgc ttttttgttc tatcgtttag
     9601 gagactttta tgaactattt tacgaagatg cgatcaaagc gtcacagctt ttggaattaa
     9661 cgttgacgag cagaaatcga aatgcagaag aacctattcc tatgtgcggt gtacctcacc
     9721 atgcagcaca aggatatatc gatgccttga ttgaaaaagg ctataaagta gcgatttgcg
     9781 agcaggtaga agatccaaag acgactaaag ggatggtcaa gcgcgaagtg atccagctag
     9841 tcactcctgg tacagtcatg gacagcaaag gattgtcggc aaaagacaac aattttttaa
     9901 cagctgtagt tagtcaagga aatgaatttg gctttgctta tgccgattta agtacgggag
     9961 aattgaagac ggctcggttg catgatgaag aagctgtttt aaatgaagcc tctgcattgc
    10021 agacaaaaga actcgtatta ggcagtgaga tcactgatac ccttcgtgaa cagctaagcg
    10081 ggcgtttagg gctagtcttt tctcaacaaa atgagatgga agaaaacgcg gaatttagct
    10141 ttttgacaag cgaactagtc gatccgctgg aaaaagaagc aaccggcaaa ctattgactt
    10201 atttatcggt gacacaaaag cggagtttag ctcatatcca aaaagcagta gaataccaac
    10261 cagatcattt tttgaaaatg gattattatt caaaattcaa cctagaatta agccaatcta
    10321 ttcggactgg gaaaaagcac ggcactcttc tatggttgtt agatgaaaca aaaacagcaa
    10381 tgggtggccg tttactaaaa caatggctag accgtccgct tatccaggca aaacaaatta
    10441 aagcaagaca agaaatggtc gcttctttgc tagacagcta ttttgaacgt atcgatttgc
    10501 agtcagcatt aacgaaagtc tatgatctgg aacgcctagc aggtcgagta gctttcggta
    10561 atgtcaatgg gcgagacttg atccagctga aaacttcttt agaacaagtg ccaatgatca
    10621 gagggttgat tgaaggaatc gatcaaggtc aatggcaaag tctgctttca gaaatgcagc
    10681 cgatggacca tctcgtccaa ttgatcgacc aagctatcca agatgatccg ccgttacaaa
    10741 taacggaagg aaacatcatc aaagatggat tcaatgagca gctcgatatg taccgttctg
    10801 ctatgagaaa cggaaagaaa tggttggcag aacttgaagc aaaagagcgt caagaaacag
    10861 gaatcaagaa cttaaaaatc ggatttaacc gcgttttcgg ttattatata gaaattacaa
    10921 aagcaaatct tggaaatgca gaactggaga agtatgaacg aaaacaaact ttagcaaatg
    10981 cagagcgttt catcacacca gaactaaaag aattggagac acaaatcctc gaagcagaag
    11041 aaaaatctgt tgatttagaa tatcagttgt ttttagctgt gagagaagaa gtcaaaaagg
    11101 ctatccagcc gctacaagta cttgcaaaag caatcagtgc agtagatgtg ctacaaagtt
    11161 ttgcaacgat cagcgaacgc tatcagtatg ttcggccaga acttgtcagt gacaagcatc
    11221 agcttctgat caaagacgga cgacatcctg tagtagaaaa agtattagga catcaggaat
    11281 atatccctaa cagcgtagaa atggcagaag acgaaatgat cttgctgatt acaggaccga
    11341 atatgtctgg taaaagtacg tatatgcgac agttggcatt aactgttctg atggcgcaaa
    11401 tgggctgttt cgttccggca aaacaagcag ttttacctat ttttgatcgg atttttaccc
    11461 gaattggtgc aagtgacgac ttaattgctg gacaaagtac ttttatggta gagatgatgg
    11521 aagccaatca agccctgcgt tatgctacgc caaacagttt gattttgttt gacgaactag
    11581 ggcgaggaac agcaacctat gacggaatgg cgttggccca agcaatcatc gaatatatcc
    11641 atcgtcatgt acaagcaaaa acactctttt ctactcatta tcatgaactg acggtacttg
    11701 agaaagaact tccgcagctt aaaaatgtcc atgttggagc cgttgaaaaa gacggagaag
    11761 ttgtcttctt gcataaaatg atggatggac ctgcggataa aagctacggc atacatgtgg
    11821 caaagatcgc aggattgcct tccaatctac tagaacgagc agcagatatc ctgcatacgc
    11881 tagaaaatgg cgataacgga caccatactg ttccagctga agtagaagag aaaactaaaa
    11941 cagccaaaca ggagcaaata aaaccacctg cagaaaaagt aaatcaagac catatacaag
    12001 accgtgtaaa agaagaaaac caacagcttt ctttattcag tgaattatcc gaaaatgaaa
    12061 cagaagtcat tgaatcactg aagcaaataa atttactaga aatgacgcca atggatgcac
    12121 taaacacatt atatgaatta caaaaacaac tgtaggaaga aggcggatat cgatggccaa
    12181 aatccaagaa ttatctgaac gtttagctaa tcagatcgct gcgggagaag tagtggagcg
    12241 accagcttcc gttgtgaaag aattagtgga aaatgcaatt gacgccggca gtactcagat
    12301 tgatatctta gttgaagaag cgggactgcg gacgatccaa gtgattgata acggagaagg
    12361 cattttggca gacgacgtag agaatgcctt caagcggcat gcgacaagta agatccataa
    12421 tcgcgacgat ctttttcgca tacgaacgct gggctttcga ggggaagctt tgccaagtat
    12481 tgcctctgtt tctgaaatga ctctggaaac ggcgaatcag gaagaaaaac aaggcaccta
    12541 tctgtcgctg aaaggcggag aagttattga gcatcgacca gcaccactgc gtcaaggaac
    12601 gaagattacc gtcagcaatc tgtttttcaa tacgccagcc cgcttgaaat acgtgaaaac
    12661 actgcacaca gaattagcga acatcgggga catcgtcaat cgactggcat tgagtcatcc
    12721 atcgattgct tttcgtttag tacatgatgg aaacaaaatg ctggcaactg ctggaaatgg
    12781 cgatctgaaa caaacaattg cgggaatcta cggattatct accgcaaaaa aaatgctgaa
    12841 aatcgaagga aaagatctag attttgagtt atttggctat gtttcattgc ctgaggtgac
    12901 tcgtgccagt aggaattact tatcgacgat catcaatgga cgttttatca agaacttttc
    12961 cttgaataaa gcaatcgttg caggttatgg gtcaaaatta atggtcggtc gtttccctat
    13021 tgctgtattg gaaatcaaaa tggacccgct tttagtagat gtaaatgttc atccgacgaa
    13081 gcaggaagtc cggctgtcga aggaaaaaga actaacagag ctaattagta acgccattca
    13141 aaaagcattg tctcaagaaa atctgattcc aagtgcagcg gataatctac ggtttaagaa
    13201 aaaagtacct gatcagccta aaacagaaca aatcgaaatc gatttgtcct acgcttttga
    13261 agaagaaaaa cctaaaaagc caagtagttt gaattttgat cgagagacag gtaccttttt
    13321 cgtagaagaa ctaaagaaca catttgttga cagaattgtt gataagtctg tggaaaatgt
    13381 tgaaaactat tctggttttt ctgaagaaaa caccacttat ccagaaaaaa cagcgaaaac
    13441 ggtggataag tttggtgaaa atgttgataa ctttgtagaa aaaacagtgg aaaaatctga
    13501 aaagaaagaa tttcccattg tggataacat ggagaaaaca aatgaagaac aagcagataa
    13561 atccgtagaa gaggatgaaa agatttacga ggaagaattg acactccatc ctgaatttga
    13621 tttcactcaa ggaaacgaca aaacattaga acaagccatc aagaaattag aaacggaaaa
    13681 accagtacaa cgttttcctc agttggaata ttttggacag atgcacggaa cgtatctttt
    13741 tgcccaaagt agcgatgggt tgtacatcat tgatcagcat gctgcccaag agcgcattaa
    13801 gtatgaatat ttccgggaaa aaattgggga agtatctgat gatctgcaag aattgcttgt
    13861 tccatttgtg ttagactatc caaacagtga tgctttgaaa ttaaaagagc aaaaacactt
    13921 gctagaagat gcagggattt atttagaaga atttggtcaa aacagcttta ttgtacgggc
    13981 ccatcctact tggtatccca atggagaaga agaatcgatt attcgggaga tgatcgatat
    14041 gctgctgaca actggaagtg tgagtgtaaa aaaattccgt gaagcaacag caatcatgat
    14101 gagttgcaaa cgatcgatta aagccaacca ttatttgaat gaagcacaag cacgtgtgct
    14161 gctgaaggat ctggcacgat gcgaaaatcc tttcaattgt ccccatggcc gtccagtatt
    14221 gattcacttt accaattcgg atatggaaag gatgttcaaa cgaatccaag acccgcatta
    14281 agtcaaagag aagagggaaa acatgaagat tgtattagca tcccaatcac caagaagaaa
    14341 agagttattg gctcatatcg tttcagaatt cgagattgaa cctgctgata tcgatgaaac
    14401 gccatttcca gacgaacagc ccgtcgatta tgttcgtaga atggctgaag aaaaagcacg
    14461 aactgtctgg gaacaagatg aaaaagaaga ccatttagtg attgccagtg acacgactgt
    14521 tgttctcaat caagagatca tgggtaaacc agaagatctg gctgaggctg aattcatgct
    14581 gaaaaaacta agcggggaaa cacatactgt atatacagct gttgttttaa aaacaaagga
    14641 acgagaagaa cggatactag cagaagcaca tgtcactttt tatcctttga cagacgaaga
    14701 gatcaaacgc tacttggaga cgggggatta tgcggataag gcaggggcat acggcatcca
    14761 aaatgctgcg agtgtattcg tcaaagaaat ttctggagat tattacagta tcgtaggatt
    14821 tccgattggt gctgtcaatc aggcactgaa aacattcatt taaacaaaaa agcggactat
    14881 ctgattttcg attgaaaatc catgatagcc cgtttttttt attgaaaaga ttacttatct
    14941 actctgacta agattttact tcagctttac cgactgcttc gcccgggcga acaagtcctg
    15001 attggtcaag agaaagtcct gcaacttttt cattattggt caaagcaaca ataatgtcag
    15061 ttttcttgcc agcttgttct atttctggca aatccatttc agcaatcagg gtctctggtg
    15121 tgacaaggta tccttctttc acgaatacat tgaaaggaac accctttagt tcaacagtat
    15181 ctaatcccat gtgaacaagt acttccagcc cctcattaga aagaatacca atggcatgtt
    15241 ttgtttcaaa gacactcgtc actttaccgt ttactggtgc atagactttg ccgtttgacg
    15301 gttcgacagc ataaccgtca cccatcattt tttgtgagaa aactgggtca tttacttcag
    15361 ttatttcctt gatggtccct gcagcgactg cgaataatgt ttcttttgtt gcaactgccg
    15421 taccagttgc tgaaacaggt tcgaaagact gtggcgttgc tgttgcgcca tttgctgttt
    15481 gaagttgtac atcagcagca ttttcaggaa cagcaggatc aatcttattc aaaattccct
    15541 gacgtctaaa gatgatcgtc aagccaaatg gaatgatgac agcaatgatc attgcgatga
    15601 tgaaaggtac ccatgtttct gcttggatag ctagtattcc tggcaaaccg cctactccga
    15661 tcgcgttagc tcgaacaccc atcaagttag caaacatgcc agctaatcca gagccgacca
    15721 ttgcagcgac gaaaggatag acgtatttca aattgattcc gaacatagca ggttcagtta
    15781 cgcctaagta acaagaaatc attgctggaa tcgagatttg ttcttctttt ttattcccac
    15841 gatgtaagaa gatgatggct aagactgcag agccttgggc gatatttgat aaagcaatca
    15901 tcggccataa attcgttgat ccgaaatctg caatcagctg catatcgatg gcattggtca
    15961 tatggtggag accagtaatc actaaaggag catacaggaa tccgaatacg gcactaaaca
    16021 accagctgat agaagacgtc aatccagtat ttacgatatt tgagatccag cttccgactg
    16081 tccagccgat aggacctaaa ataacgtgtg cagctaaaac agttggtaac aatgaaaaca
    16141 atggaacaaa aatcatcgag atcgactgag ggatatattt gcggaagaag atttctagat
    16201 acgctaacat aaaccctgcc agcatggctg gaataacttg cgcttgataa ccaatcatct
    16261 ggacttgagc aaaaccaaaa tcccaaaatg gaatatctgc tgcggctgtg gaagctacac
    16321 tataagcatt taataattgc ggagaaacta acgtaattcc taaaacgatt cctaatattt
    16381 gtgtagtacc catctttttt gcaatactcc aagtgatacc tactggaaga aaatggaaaa
    16441 ttgcttcacc cggtaaccac aaaaaggcat tgacaccatt ccaaaacttc gagtgttcaa
    16501 cgattgttcc accaagactt tcaaactgga taccttcaag tacatttctg aatccaagga
    16561 tcaatccacc gacaatgatt gcaggaatca gtggtgtaaa gatttctgct aaaacggcaa
    16621 tagcacgttg aacgggatga aggttttgtt ttgcagctgc ttttccttgt tctttggaaa
    16681 ccccttcaac tccagatact gcaacgaagt cgttataaaa agtagaaaca tcgtttccta
    16741 tgatgacttg gaactgtcct gcattcgtga acatcccttt tacgctaggt atatcttcga
    16801 tcgctttttc gtccgctttt cctggatcat tcaggacaaa acgcatacga gtcgcacaat
    16861 gactaactgc agcaatattt tcttttccgc cgatatcatg taacagcttc tcggcatctg
    16921 cttgatattt tgccatatca ataaacccct ttctcttaac ttgtctatgc aagttgtttc
    16981 ttcatttact atactttttt tcggagagaa ttgcaagcgt tttattaaaa agtacgagag
    17041 aaaatgatat cgttttaaaa agcttaaaat aagcttttct taaaaatagg aacattgaaa
    17101 tacaaaaaga gctgtagtat agtgaagaaa tgatggaaga acgagtgagg gaaaaaacat
    17161 gaataagttc aatgaaattt ttttagattt ggaacagaaa attttagcga aagaatatcc
    17221 tccgcattcg cttttaccca gtgagaacca attgatcaaa atttatggtg tttcacgaga
    17281 aacaattaga aaagcgctga atcttttgac tacggaaggt tatattcaaa aaaaacaagg
    17341 aaaaggttcg atcgtactgg atcggaatcg cttcgacttt cctatttctg gattgactag
    17401 ctataaagag ctacaggaga cccaacgtat tccaagtgaa acgatcatcc atacgttaga
    17461 agaaacagaa gtgacaaaag cattgaacga gatcactggc tgggagatcg gtgcgcctgt
    17521 ttggcatttg atacgcgaaa gaaaaatcaa tggcgaagta gttatattag acaccgatta
    17581 tctattaaag gaaatcgttc ctattttaac tccagcacaa gcacaaggat cgatctatga
    17641 atattttgaa aatgagcttt ctttgacgat tgcttacgcg caaaaggaga tcacagtaga
    17701 agaagtaacg gaaatcatga aaacagcgat ggatcttcac gatgacactt atgcagtagt
    17761 agtcagaagc ctcgttcatc tggaagatac ccgctgtttc gagtattctg agtcggttca
    17821 ccgattagat aaattccgtt tcgttgagtt tgcccgacgc cgaaaagtgt aaatagttca
    17881 aaagaaagca aattgttggc atctgtccac tttggcgcta tgataggatc acaaaggggg
    17941 catttttaat ggataaacca ataagaccag aaaaagaaga actgaaagaa aagttatcac
    18001 ccatggctta tgcagtcaca caagaaaatg caacagaacg accatttagc gggaaatatg
    18061 atgattttta cgaaaagggg atctatgtag atatcgtcag cggtgaaccg ttattcagct
    18121 ctgcagaaaa atatgatgca ggttgtggct ggccatcatt cagcaaacca ataacgaaaa
    18181 gacaagtgcg cgaaaaagcc gatttttctc atggcatgca tcgaatagaa gttcgaagca
    18241 aagaagcaga ttctcatctc ggacatgtgt ttaccgatgg accagtagat caaggtggtc
    18301 tacgttactg catcaattct gcctcactga aattcattcc atatgaaaag atggatgaat
    18361 taggttatgg ggaattcaaa tcacttgtag aataatggaa atacacaaag agcggtacaa
    18421 tacggggatt tactcgatcg tccgctcttt ttttattcaa gcgattgcta tttgaaagaa
    18481 acgctcccta gactcctttt ttcacaaggt gaaatgtgct acaataaagg gaacgtatgt
    18541 gtgcaaaaga aagaggacta gaatatgtat gaatatctga caggtgtggt tacctttatc
    18601 aacccctatt acatagtagt agaaaccaat ggtatcggct accagatcgc actaggaaat
    18661 ccttaccgct acagtagcaa actaaatcaa aaaataaaaa tttatgtcca tcaggtaata
    18721 cgtgaagatg cgcatcttct gtatggattt gattcgctag aagaaaagca actgtttttg
    18781 cgattagtaa gtgtttcagg aatcggtccg aaaagtgccc ttgcaatcat ggcaagcgaa
    18841 gaccactccg gtttgattca agcagtagaa tccagtgatg tcacttattt gacgaaattt
    18901 ccaggagtag ggaaaaagac agcacaacaa atgatcttgg atctaaaagg aaaattcggt
    18961 gagctgagta tcgatacacc ttttagtcta tttgatgaag caaacacaaa agacgctaca
    19021 gctctatctg aagcaatgga agctctctcg gctcttggtt acagtgatcg agaaatcaaa
    19081 cgtgtagaaa aacaattaaa agaagtagat aatcagacaa cggatgagta tctacgccaa
    19141 gcactcaagc taatgatgaa aaaataagga ggagaccaaa tgacagatga atacttgtta
    19201 tcaccagaat ctggcgaaaa tgaactgagt ttggaaaaat ctcttcgacc acagctgctt
    19261 tctcaatata tcggacagag aaaagtcaaa caagaacttc agatttacat cgaagctgcc
    19321 agaaatcggg aagaaccttt agatcatgtt ctgttgtacg ggcctcctgg attaggaaaa
    19381 acgacgatgg ccatggtcat tgctaatgag atgaccgtaa atattcgtac gacgagtggc
    19441 cctgctatcg aacgtccggg tgacttagta gcaatcttga atgaactgga agcaggggat
    19501 gtcctgttta tcgatgagat ccatcgatta cctagagtgg tagaagagat gctttattca
    19561 gctatggaag atttctatgt agatatcatg gtaggacaag ggccaaccgc acatccggtt
    19621 catttccctc ttcctccctt tactttgatt ggcgcgacga cacgggcagg tatgctttct
    19681 gcacctttac gagatcgatt tggcatcatt tctcatatgg aatattatga cgaacaggat
    19741 ctgcaggaga tcgttttacg ttcttcggat atttttcaaa cagagatcat tgaagaaggg
    19801 gcattggaaa ttgctcgccg atcacgagga acgcctagaa tcgctaatcg cttgctcaaa
    19861 cgggttcgtg attttgcgca agtccaagga gacgggaaaa tcgatcgtcc tatagcggat
    19921 caggcactta ctttgctaca ggtcgatcag gctggattgg attatgttga ccagaaattg
    19981 ttgcgaacaa tgatcgagtt atatggcggc ggaccagtag ggttaagtac gctttcagta
    20041 aacataggag aagagcgtga gacggtagaa gatatgtatg aaccgtatct gatccaaaaa
    20101 ggatttttaa agcgtacacc tagagggcga attgctactg cttatgccta tgaacatttt
    20161 ggttacgact atcatatatg atttttgctt ttagattgga ggaaaatgaa tgagtgatac
    20221 aacacgtacg aaacaattga tcaaaaacgt attgattgat ttgtgccaaa cgcaatcttt
    20281 tcgaaaaatc agcgtccaaa aaatcgcaaa cgaagcaaaa atcaatcgac aaacatttta
    20341 ttatcatttt acagataaat acgatttgct tcgttgggtc tattgtgagg atgcattgca
    20401 ttatttagat ccacaatgtc tttcacttga taattgggaa gagcaagcat tgaaaatgct
    20461 gaaagcaatt gctgagaaga aagaatttta tgcaaatact gtgctttctg acccagaaat
    20521 tttacaaaaa gagttttctc aactgatcca aaaatcattt atcaagattt ttgaacaaat
    20581 ggatgaagaa agacaacttt ctgcaagaga caaactattt tatgctcgtt ttttttctta
    20641 cggttgcagt ggtgtattag tcaattggat cacgaatgaa tatgaagaaa caccgatgga
    20701 aatcgctatg cagcttttcc gtttagccaa ggatacggaa ttatattctt atcgtcttta
    20761 tgcaaaagaa gagttggaag aacagtaata gaaaaatttt ttgttggaaa agcaataatc
    20821 gctaaaagga gatggggaaa tgacaaaaat tttatttgtt tgtttgggaa atatttgccg
    20881 ttcaccgatg gcagaaggct tgctgagaaa acgaatagca ttagaaggaa gggaagcaga
    20941 attttttgtg gattctgctg ctacaagcac gtatgaagtt ggaaagacac cgcaccctgg
    21001 aacgaaaaaa atattaaacc aagaaaaagt agatatgacg aatatggttg ctcggcaaat
    21061 cacaccccac gattttgaaa cttttgattg gatcattggc atggatcaag aaaatgtaga
    21121 agaactgaaa cgaagagcac cacgctcagc gcaggggaaa atccatttgt ttttaagtag
    21181 cattcctgga aaagaaaaag aaaatgttcc cgacccatac tataccaata actttgatga
    21241 gacatatcac ttgatcacag aaggcctgaa tcattggtgg aatatttgga ttgatgaaaa
    21301 taaaataaca aacaatttgt aaagttaacg ctttcttttt aaggcgatgt tagagcattt
    21361 ccttgttttt ttgtaaaatg ttaggtaaaa taaaattaat taagtaacac tttcttagct
    21421 aaaggaggag tgcattcgat gaacgaagag acagtatcgc caatgaagaa gcttacgaag
    21481 ttagttactc atacttcgta tcaacttttt gattcttttg taaatgacac tgaagaacat
    21541 gctaagaatg tacgattgca aggaaagttt attcttgagc tgcaaaaagc tgctactgaa
    21601 catagtctag ttatcttaca agtaagagca aatcgtttga gtagcaagta tgaaacgatc
    21661 tcaggctggg tggcgacaaa aacggtcgaa aaagaccgag tgatgatccg cctacaaaac
    21721 gaagagcagc agatccggat ggttcctgta gaacaaattg aaaaaataac aatcctttca
    21781 ccagcagggg aacaggaacg gttatcaaaa taatttatac cagatagaaa agcacgtatg
    21841 agcttgtacc atcaatcatt actaatcaaa aataaccgaa tgctttaagc tgatatcagt
    21901 aaaacggaac gttttaggat gagtatcata gcatgacagc attcggttga ttagttgaat
    21961 cgattggatg gtacaagttt ttttgataaa aaaaggtcct gctagccggg gagctagcag
    22021 gataaggagt taaaaatgaa aaagtgttgt tagggttgtt tgttggtatg cttatataat
    22081 agtcattagt tgtgaatatt ttgtgacgaa agttttcgaa agttgttaag tt
//
LOCUS       DACBZK010000044        21371 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.045, whole genome shotgun sequence.
ACCESSION   DACBZK010000044 DACBZK010000000
VERSION     DACBZK010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21371
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.045"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            131..505
                     /locus_tag="IVD66_001752"
     CDS             131..505
                     /locus_tag="IVD66_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAP6145974.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="IVD66_001753"
     CDS             complement(619..1248)
                     /locus_tag="IVD66_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP6145975.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="IVD66_001754"
     tRNA            complement(1382..1454)
                     /locus_tag="IVD66_001754"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="IVD66_001755"
     tRNA            1668..1741
                     /locus_tag="IVD66_001755"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            1696..1845
                     /locus_tag="IVD66_001756"
     CDS             1696..1845
                     /locus_tag="IVD66_001756"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6145976.1"
                     /translation="MTVNHDVVGSSPTAGVNKAYAKKKKSNHLGFFFFYYYDESSFLF
                     LSRML"
     gene            2338..3666
                     /locus_tag="IVD66_001757"
     CDS             2338..3666
                     /locus_tag="IVD66_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAP6145977.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="IVD66_001758"
     CDS             3868..4701
                     /locus_tag="IVD66_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HAP6145978.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="IVD66_001759"
     CDS             4717..5454
                     /locus_tag="IVD66_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HAP6145979.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="IVD66_001760"
     CDS             complement(5609..6577)
                     /locus_tag="IVD66_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HAP6145980.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="IVD66_001761"
     CDS             6809..7642
                     /locus_tag="IVD66_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HAP6145981.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="IVD66_001762"
     CDS             7676..8515
                     /locus_tag="IVD66_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP6145982.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="IVD66_001763"
     CDS             8541..9101
                     /locus_tag="IVD66_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAP6145983.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="IVD66_001764"
     CDS             9300..11021
                     /locus_tag="IVD66_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HAP6145984.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="IVD66_001765"
     CDS             11186..12328
                     /locus_tag="IVD66_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP6145985.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="IVD66_001766"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="IVD66_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HAP6145986.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14775
                     /locus_tag="IVD66_001767"
     CDS             14128..14775
                     /locus_tag="IVD66_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAP6145987.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     gene            15168..17813
                     /locus_tag="IVD66_001768"
     CDS             15168..17813
                     /locus_tag="IVD66_001768"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HAP6145988.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18123..19436
                     /locus_tag="IVD66_001769"
     CDS             18123..19436
                     /locus_tag="IVD66_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HAP6145989.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19426..20079
                     /locus_tag="IVD66_001770"
     CDS             19426..20079
                     /locus_tag="IVD66_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP6145990.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20134..20805
                     /gene="radC"
                     /locus_tag="IVD66_001771"
     CDS             20134..20805
                     /gene="radC"
                     /locus_tag="IVD66_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HAP6145991.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGIYKLVHINYIRKFTVILPSGNTIMLSIIERHNAFFSS
                     SEDSL"
     gene            complement(20700..>21371)
                     /locus_tag="IVD66_001772"
     CDS             complement(20700..>21371)
                     /locus_tag="IVD66_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6145992.1"
                     /translation="NKNYCPPIIDKKLFYAVQKALPKNLKTNAKRDYIFKGLLKCSDC
                     QGSVAGQTIKARYKKKDGTESIYERTCYRCVKRRNNKLRCTNKRAFYEKNLERYIFEA
                     TKQKFEQIQINYSKKQPKIIKKKNSKKNIENKLDRLKKAYLNEVIDLEEYKKDREALM
                     KELNEIEVEPAKIDIKNVEFILSKEFDEIYKESSEEEKNALWRSIIDNIIVFPDGNIT
                     VNFLI"
BASE COUNT         7173 a         3559 c         4386 g         6253 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaaga tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggctatga tgtccctttt
    14341 cttatcgatg tattcaataa tatccttaat actaaagaag aaaaacgaat cgcattagta
    14401 ggatatggaa atcttggcaa agcattgaaa cacaacaatt ttagaagaaa tgaaaatcta
    14461 aatatcgtgt gcgtctttga taatgatcca gcactgatca atcgagtaat tgatggagaa
    14521 atgatctatc cgattgatcg tttcgcggag atagccaaag caaaaaatgt gacagtagca
    14581 atctctacgg taccaagtaa atattcacaa tctgctattg atgaaattgt caaaggaaat
    14641 gtaaccgcta tacttaattt tgcgcctgac agagtaactg tcccagctta tgtcaatgtt
    14701 caatacattg atttgacaac cgagttgcag acgcttattt actttgatga gaattactca
    14761 gaagtttttt cttaggaaaa tttgagtagg cttattgatc ttgcgagaac tcgtcgtaat
    14821 tctttcaaaa attttttagt actaaatgaa gtggtttttt cacgaccact tgttgactaa
    14881 aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa gaggagtaac tggcacattc
    14941 attcttagag agagaactat ctgctgaaag gttctcaatg acaaccagtg aaggtagctt
    15001 gggagtttct gtcttgaatg gagtagagat agacgagtcg tgatcgttaa ctcacttgag
    15061 aggcaataat gattgattat tgcaatttag gtggtaccgc gtaaatcata cgtcctagaa
    15121 tacgaaagta ttttaggacg ttttttagtt taaaggagga aaacagcatg acggaagaaa
    15181 ataacctatc aacaaaatat aatccgcaag aagttgaagc tggacgttat cagcattggt
    15241 tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc aaaaccttat tcaatcgtaa
    15301 tcccgccccc aaatgttact ggaaaacttc atttagggca tgcttgggat acgaccttgc
    15361 aagatatgct gattcgtcaa aagagaatgc aaggatatga tactttatgg ctgcctggta
    15421 tggaccatgc aggaatcgcg acacaagcaa aagtagaagc gaagcttaga gagcaaggga
    15481 tttctcgtta tgatctaggt cgtgaaaagt tcatcgatca agtgtgggaa tggaaagaag
    15541 agtatgcgag ccacatccgc gaacagtggg ctaaaatggg cttatcttta gattacagta
    15601 gggaacgttt tacattagat gatggattat ctgaagcagt acgtaaagtt tttgttacct
    15661 tatacgaaaa aggtttgatt tatcgtggtg aatatatcat caactgggat cctcaagcac
    15721 gaacagctct atctgatatc gaagttattc ataaagatat cgaaggcgcc ttttatcata
    15781 tgagctatga actagcagat ggatcaggcg tagtagaaat tgcgacaacc cgtccagaaa
    15841 cgatgttggg agatacggcg attgctgttc atccagaaga cgagcgttat caagcgctca
    15901 tcggcaaaaa agtgattcta cctttagtca ataaacaaat cccaatcatt gcagatgaat
    15961 atgtagatat ggaattcggg acaggtgtag taaaaatcac tccagcacat gatccaaacg
    16021 actttgaggt aggtaatcgt catgatcttc cacgcgtaaa tgttatggat gatgatggta
    16081 cgatgaatga actagcagga aaatatgctg gaatggaacg ttttgctgct cgtaaagcaa
    16141 tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat cgatacgatg atccacagtg
    16201 tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg gctgtctact caatggtttg
    16261 taaaaatggc gccgttagcg aaaaaagcca ttgataacca agaaacagat caagcagtgg
    16321 aattcttccc tccaagattc aatcaaacgt ttttacgttg gatggaaaat gtccatgatt
    16381 gggtaatctc acgacaatta tggtggggac atcaaattcc tgcatggtat cacaaagaaa
    16441 caggtgaaat gtatgtaggg atggaagcac cagcggatag tgaaaactgg gtacaagatc
    16501 ctgatgtttt agacacttgg tttagttcag ctttgtggcc tttctcaaca atgggctggc
    16561 cagatacgga aagcgaagat tataagcgat acttccctac tagcacttta gtaaccggtt
    16621 atgacatcat tttcttctgg gtaagcagaa tgattttcca aagcttggaa tttactggcg
    16681 aacgtccatt tgagaatgtc ttgattcatg gattgattcg tgacgaacaa gggcggaaga
    16741 tgagtaaatc attaggtaat ggaatcgatc cgatggaagt aatcgaaaag tatggagcag
    16801 atgctctccg ctggttctta tcgaatggtt ctgcaccagg acaagatgtc cgcttcagct
    16861 atgaaaaaat ggatgcttct tggaacttta tcaacaaaat ctggaatgct tcacgtttcg
    16921 ttatcatgaa tatcgaagga atgaccgtag aagagatcga tttatctgga gaaaaatcag
    16981 tggctgaccg gtggatcctt actcgtttga atgaaacgat cgaacgagta actgagctat
    17041 ttgatcgttt tgaatttggt gaagcaggtc gacaactgta taactttatc tgggatgatt
    17101 tttgtgactg gtacatcgaa atgagtaaag aagtacttta tggagatgat gctgtttcaa
    17161 aacaaaccac ccgtagcatc ttagtccata cacttgatca gatcctacgt ttattgcatc
    17221 caatcatgcc attcgttaca gaagaaatat gggaacatat tcctcatcag ggaaattctc
    17281 tagtagtggc agaatatcct gttgtacgtc cagagtttga tgatgaaaca gcttctaaag
    17341 ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa tattcgttca gaagtgaata
    17401 caccattgtc taaaccaatt acgttgctaa ttaaaacaaa cgatgctaaa atcgatcaat
    17461 ttttagttga aaatacaagc tatatcgaac gcttctgtaa tcccgaagag ttgacgatat
    17521 caagtgagat cactgcgcca gatctagcga tgtcagctgt tctgacaggt gcagaaatct
    17581 tcttgccgtt agcaggattg atcaatattg aagaagaaat caaacgatta gaaaaagaac
    17641 tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa actttctaat gaacgttttg
    17701 tttctaacgc gccggaagaa gtagtagagg cagagcgtgc aaaagaaaaa gattatttag
    17761 agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg tactattcaa taagaataga
    17821 aaaagagagt gtgaaatcag ctagctatta ctaaaagcta gctgattgaa catcgttaca
    17881 ggaaagagtt tgagcctcac tcttagcttc gattcataag gagatgtgac ataaattttg
    17941 tcgcatctct tttttagtct actcttatta tgtaggagaa ggagggaggt ggatcatgta
    18001 tcaagagtca ataaagtagt tgataaaatc gttcctctct ctgtttcttt tctctttgtc
    18061 atacttttat ttttcttatg tgttctattt gttataataa aagagaaatg ggggaattgt
    18121 tgatgacgat tgaagaagca atagaatgga tccatagtcg attaccattt ggttcacgtc
    18181 ctggccttga ccgagtcgaa gctttattag aagtggtagg gcatccagag agaaaagtaa
    18241 aaacgatcca tatcgctgga acaaacggaa aaggttctac tgtagcttat ttgagaagcc
    18301 tattagaaga ggctgggctg acagtaggta catttacttc accttatatc gaaacgttca
    18361 atgaacggat cgcaatcaat ggcaaaagca ttccagacaa tgatttgatc cagcttgtaa
    18421 aaaaatatca gccactgatc aaacaacttg atcaatttga agcagtagct ggtattactg
    18481 aattcgagac attaacagca atggcatttg attatttttt gatgaagaaa gtggacgtag
    18541 cgattatcga agttggctta ggcggcttat tggattctac caatgtagct gtaccaatgc
    18601 tgacgggaat aacaacgatt ggacttgatc ataccgaaat acttggagat acaattgaag
    18661 aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt tccagtagta acaggaaata
    18721 ttgccccaga agcttttact gtcatccaac aaacagctaa agcaaaaaat gcaccgcttt
    18781 atgtatacgg ggaaaattat aaaataaact atctgcatcc tgatgagatg tggggagaag
    18841 tatttgaatt ttttaatgaa ataggaaaga tccctcaatt aaccactccg cttttagggc
    18901 aacatcaagc tgaaaatgca ggagtagcca tcgaattgta ttttgtttac tgtcaattgg
    18961 aaaagctgcc tttccgagaa aaagatgttt tgaagggatt gaagaaatct cgatggccag
    19021 gaagaatgga gcgtttgagt aacgagccat tagttgtttt agatggtgcc cataatacgc
    19081 atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt caaaggatat caaatcaaca
    19141 ttttgttttc cgccttacga actaaaaatg ttagagaaat gctagaacga ttgcagcaag
    19201 taccaaatgt ccatatttat ttgacgacct ttgaacatcc aaaagccatc gaattaagtg
    19261 aagtatcaga tttagcaagt gagagagtat caatcgtttc attgtggcaa ttcggattag
    19321 cagatatatt ggaaaagatg acaaatgaag acgtattagt tgtgaccggt tcactttatt
    19381 tcatttcaga agttcgccat ttattaatac aattaggagg agatcatgaa gtataatgca
    19441 gtgatttttg acatggatgg tttgctgttc gacacagagt tagtgtatta cgaagccaca
    19501 caagtagtag cagacaagat gggttttcct tatgataaag acctgtattt aaaattctta
    19561 ggtgtttcag atgaagaagt atgggcgaat tatcatatga ttttctcgga atttggcaaa
    19621 acaagtgtac aaagattcat agatgattca taccaggaaa cgcttgaacg tttttcgcaa
    19681 ggagcggtac aaatgaagcc cggtgtgttg gaactcctct cttttttaga agaacatcag
    19741 attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca ttgaactttt attgaagaag
    19801 aacaatctgt ttgaacgatt tgagacgatt gtttctgcag aaaatgttca acgagcaaaa
    19861 ccagacccag aaattttctt gttagctaat cagaagctag gtacagcgaa gaaagaaaca
    19921 ttgattttag aagattcaca aaatggtatt ttagcagctt ctgcggctga gatcccggta
    19981 gtcatggtac cagatctgct tccaccatcc caagaattga tcaaaaaaac agctggggtt
    20041 gtttcttctt tacatgaaat ccctgcattg ttaaaataaa aatccatctc ttttcgtatc
    20101 ttattttaga taagatagaa aggagatgtt tttttgggaa aacgattgat caaagaagta
    20161 cctactagct ctttaccaag ggaacgtatg gaaatttatg gcgcggaagc tttatcggat
    20221 caggagcttt tggcaatctt actgcgtacc ggtcaacacc cttatagtgt gatgtcgatt
    20281 gctggaaatc tgttaaaaac gtttggagga ctggcctctt tacgacaggc tactttgcat
    20341 gagttagaag agattcgagg gataggacgc gtgaaagcaa tcgaaatcaa agccttgatc
    20401 gaattaggtc gacgaattca gacggatcat gaaagagcgg ctccaccggt tcgtaccagc
    20461 tacgaattgg cccagcaatt gattctggaa atgaaagatc acaaacaaga acatttggtt
    20521 tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa aaacagtgtt catcggttcg
    20581 ctgaatcagt cagtcgctca tcctagagaa attttccatt atgctgtacg ttattgtgca
    20641 gcaaggatcg ttttagcgca taatcatcct tccggaatat ataagttagt acacataaat
    20701 tatataagga aatttactgt tatattgcca tctggaaata ctattatgtt atcgataatt
    20761 gaacgccata atgcattttt ttcttcttcc gaagattctt tataaatttc atcgaattct
    20821 tttgatagaa taaattcgac attttttata tctattttag ctggctctac ttcaatttca
    20881 tttaattctt tcattaaagc ttctcgatct tttttgtatt cctctaagtc tataacttca
    20941 ttcaagtagg ctttcttcaa tctatctaat ttattctcaa tatttttctt actatttttc
    21001 tttttaataa tctttggttg tttttttgaa tagtttattt gtatttgttc aaatttttgt
    21061 ttagtagctt caaaaatata acgttctaaa tttttttcgt aaaaagcgcg cttatttgtg
    21121 caacgtaatt tattatttct tcgttttaca catctataac aagtcctttc gtatatagat
    21181 tctgtaccgt cttttttctt atatcttgct ttaatagttt gaccagctac tgatccctga
    21241 cagtcagaac attttaataa acctttaaaa atgtaatcac gttttgcatt tgtttttaaa
    21301 tttttaggta aggctttttg aacagcataa aaaagttttt tatcaataat aggaggacag
    21361 taatttttat t
//
LOCUS       DACBZK010000045        20782 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.047, whole genome shotgun sequence.
ACCESSION   DACBZK010000045 DACBZK010000000
VERSION     DACBZK010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20782
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.047"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(18..1574)
                     /gene="rny"
                     /locus_tag="IVD66_001773"
     CDS             complement(18..1574)
                     /gene="rny"
                     /locus_tag="IVD66_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HAP6145993.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(1985..3034)
                     /gene="recA"
                     /locus_tag="IVD66_001774"
     CDS             complement(1985..3034)
                     /gene="recA"
                     /locus_tag="IVD66_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HAP6145994.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(3143..4384)
                     /locus_tag="IVD66_001775"
     CDS             complement(3143..4384)
                     /locus_tag="IVD66_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HAP6145995.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(4624..5202)
                     /gene="pgsA"
                     /locus_tag="IVD66_001776"
     CDS             complement(4624..5202)
                     /gene="pgsA"
                     /locus_tag="IVD66_001776"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HAP6145996.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(5411..6295)
                     /locus_tag="IVD66_001777"
     CDS             complement(5411..6295)
                     /locus_tag="IVD66_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6145997.1"
                     /translation="MAFETIGEKLRQARLNKKISLDELQQITKIQKRYLEAIDNDDFD
                     QLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQPETVSTSRKAMHQ
                     EESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDTASSLKVEGSVEES
                     SSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITDATKPVTLEFTAVN
                     RVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNATIKANGESVPVNP
                     GENNQSPKNVNLTLQYAE"
     gene            complement(7073..8359)
                     /locus_tag="IVD66_001778"
     CDS             complement(7073..8359)
                     /locus_tag="IVD66_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAP6145998.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(8352..9620)
                     /locus_tag="IVD66_001779"
     CDS             complement(8352..9620)
                     /locus_tag="IVD66_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAP6145999.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            9872..10333
                     /gene="mscL"
                     /locus_tag="IVD66_001780"
     CDS             9872..10333
                     /gene="mscL"
                     /locus_tag="IVD66_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HAP6146000.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(10392..10838)
                     /locus_tag="IVD66_001781"
     CDS             complement(10392..10838)
                     /locus_tag="IVD66_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6146001.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(10931..11176)
                     /locus_tag="IVD66_001782"
     CDS             complement(10931..11176)
                     /locus_tag="IVD66_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146002.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(11290..11868)
                     /locus_tag="IVD66_001783"
     CDS             complement(11290..11868)
                     /locus_tag="IVD66_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP6146003.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(11945..12475)
                     /locus_tag="IVD66_001784"
     CDS             complement(11945..12475)
                     /locus_tag="IVD66_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HAP6146004.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(12479..13339)
                     /gene="rlmB"
                     /locus_tag="IVD66_001785"
     CDS             complement(12479..13339)
                     /gene="rlmB"
                     /locus_tag="IVD66_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HAP6146005.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(13332..13727)
                     /locus_tag="IVD66_001786"
     CDS             complement(13332..13727)
                     /locus_tag="IVD66_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAP6146006.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(13724..15136)
                     /locus_tag="IVD66_001787"
     CDS             complement(13724..15136)
                     /locus_tag="IVD66_001787"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HAP6146007.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(15133..15669)
                     /gene="cysE"
                     /locus_tag="IVD66_001788"
     CDS             complement(15133..15669)
                     /gene="cysE"
                     /locus_tag="IVD66_001788"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HAP6146008.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     gene            complement(15991..17451)
                     /locus_tag="IVD66_001789"
     CDS             complement(15991..17451)
                     /locus_tag="IVD66_001789"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HAP6146009.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(17621..18778)
                     /locus_tag="IVD66_001790"
     CDS             complement(17621..18778)
                     /locus_tag="IVD66_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HAP6146010.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(18812..20182)
                     /gene="radA"
                     /locus_tag="IVD66_001791"
     CDS             complement(18812..20182)
                     /gene="radA"
                     /locus_tag="IVD66_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HAP6146011.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(20245..20772)
                     /locus_tag="IVD66_001792"
     CDS             complement(20245..20772)
                     /locus_tag="IVD66_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HAP6146012.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         5473 a         4592 c         3706 g         7011 t
ORIGIN      
        1 ttcttttgta ttttttatta tttagcataa tcagttgcac gagtttcccg aataacgatt
       61 actttgatgt gtccaggata atccagttct tcttcgattc gtttacgaat atcacgtact
      121 aaacgaacag cgtctaaatc cgagatttct tctggcttga ccattacccg aacttcgcgt
      181 ccagcttgaa ctgcgtaact tgattctaca ccggcgaagc tgttcgaaat attttccaga
      241 cttcttaaac gacggatgta gttttctaat gattcacttc gcgcaccagg tcttgctgct
      301 gagagcgcat ctgctgcagc tacaaggaca gagataacag aagtagcttc cacatctcca
      361 tgatgagaag cgatcgcgtt gattactact gggttttctt tgtacttggc agctaattcc
      421 gcaccgatct caacgtgaga tccttcaatc tcatggtcaa gtgctttccc aatatcatgg
      481 agcaacccgg cacgttttgc taattggata tcttcgccaa gctctgctgc taagatacca
      541 gctaattttg caacctcgac cgaatgcttc aagacgtttt gtccataact agttctgaat
      601 cgcagacgtc cgatgatctt gattagatct ggatgaagtg tatgagcacc gacttcaaac
      661 gctgcctctt ccccgtattc gcgaatacgt tcatccattt ctttacgaga tttctcgacc
      721 atttcttcga tacgcgctgg atggattcgt ccatcttgta tcagtttttc caaggtcatc
      781 cgtgcgattt ctcttcggat tggatcgaat ccggaaagaa caactgcttc cggtgtatca
      841 tcgatgatta aatcgatacc agtcagcgtc tcaagcgttc gaatattacg accttctcgt
      901 ccaatgatac gacctttcat ttcatcattc ggaagggtaa cgactgaaac agtcgtttct
      961 gaaacttgat ctgctgcgca gcgttgaatc gctaatgata ataagttttt cgctttgcga
     1021 tctgcttctt ctttggcacg ctgttcagat tcttttacca ttagagttaa ctcatgattc
     1081 agctcttctt cagtcgattt catgatgaca tctcgtgcgt cctcttttga taaaccagca
     1141 attttttcta gttctttttg ttgatcttca atcatttttt caacgtcttt ttctcgctct
     1201 tcaattaatt gctgttttga actaagtgct tcttctttac tttcaagtga gttctcgcgt
     1261 ttttctaacg agtcatcttt acgattcagc gtttgttcgc gttgaatcaa acgattctct
     1321 tgagatttta attctaactt actttctctc agctcacttt caacttcaga acggtatttc
     1381 tgattttctt ccttagcttc taacaatgct tcttttttta gagtttctgc ttcttttttt
     1441 gcactatcga tgattccagc agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt
     1501 gactttgcga ccataaaccc taaaccaaga ccgacaatta aaccgatgat agcgaggaga
     1561 atgttgaata ccataaaatc cacctccata ctatcttttt catttttatc atctatacag
     1621 cttctatgat aaattattct aaactcgtca atatgcatct tcgcatatat gtgtacaaaa
     1681 aacatgcaca actttattct aatgtttgta ccccgtagtg tcaactttaa ataaacaaag
     1741 aaacggcttt ctacttattc attaaacgat ggtttttaaa ataaatgaca ctagtttcat
     1801 ataggtaaac ctttaaattg agaaactttt ctattaaatt attctttgta gatgaacaga
     1861 tatttttatt ttatgtaccc actcgtataa ttaaataact cacgatttct ttattcaata
     1921 aaaaaacggc aggtcaagga gagtacctac tcttcagacc agccgttttt gtttatcata
     1981 atttttattc ttctactaaa ggcaattctt cttgtccttt ttcatcttct gggacagcga
     2041 cttcttcacc aataccataa gctgctctaa ctagagcaga aacttctgcc atcatttcag
     2101 gatgattagc catatagatt ttagcgtttt cccgtccttg accaatccga tcttctttat
     2161 aagaatacca agcaccgctt ttatcaacaa tgtctttttc tactgccatg tctagaagtt
     2221 ctccttcttg tgagatccct aaaccataca tgacatctac ttcagcgatt ttgaaaggag
     2281 gtgctacttt gttttttacg actttgatct ttgtacggtt accaacaata tctgtacctt
     2341 gtttcaattg ttctgcacga cgtacttcca aacggatcgt tgcgtagaat ttcaatgcgc
     2401 gtcctccagg agtgatttct ggattcccaa acatcacgcc tactttttca cggatttggt
     2461 tgatgaaaat agcgattgtt tttgttttgt tgatcgaacc agagagttta cgcaatgctt
     2521 gagacatcaa acgtgcttgt aacccgacat gtgagtcacc catttcgccg tcgatttctg
     2581 ctcgtggaac taaagcagca actgaatcga ctactacgat atctacagcc ccacttgata
     2641 ctaaagcatc agcgatctct agaccttgtt ctcctgtgtc aggctgtgaa agaagtagtt
     2701 catcgatatt cacacctaat ttttgtgcat attgcggatc taacgcatgc tcagcatcaa
     2761 tgaaagcggc cgttccgcca tttttttgta cttctgcaat agcgtgtagt gcaactgttg
     2821 ttttacctga actttcaggt ccatatactt cgatgatacg tccacggggg taaccgccga
     2881 cacctaaagc gacatctaac gcaagagagc cacttggaat tgtagagatt tgttggtcga
     2941 ttttttcgcc caatttcata atagagcctt taccatagct cttttcaatt tttttcagtg
     3001 cagcatctaa ggctgcttta cgatcatctg ccaatacgat aatcctcctt atatttacaa
     3061 atcagagcaa catttcatta tccttatcat atctttttta gtgaaaaaaa gcaagaaaaa
     3121 accgaacaaa tattcgcatt tatcattttc ttaaaagctg ttttctcaaa agatcaaatc
     3181 cttgcataac cgcattatat ctgatagcag cacgatctct ggcaaagtga tatttttccg
     3241 aaaccacgcc gtctttagat gaaatagcga tccatactgt tcctgcagat tgaccttcta
     3301 acgtgtccgg tccagccact ccggtgaaag ctacactgta atctgttctt gctatctcac
     3361 gtgcttgaat ggccatctgc tccacacatt ctttgctgac tgttccatat tctgctaata
     3421 gctccggatc aatctccaga aaaccagctt ttgtttggag cgagtaggta acgaatccgc
     3481 ctggaaatac ttcagataca ccagcaatgt cgcctaatgc ggcttggaag gcgccggctg
     3541 tcaaactttc cgctgctgtt acagtctgct tgttttcttt cagtagttcc actacgactt
     3601 ttgctagcga attatcatcg ccgtatccat aaaaatattc ccctactcgt tcttggattt
     3661 tttcttctaa tgctaaaaga gcttgattcc ctgcctgaac atcatttgtt ttcactgtca
     3721 gtcgtaatgt cacttcattt ggtttggcat atggtgcgat cgttggattg atctgtgtct
     3781 caatcagatc ttttagctca gtgaccagtc gcgattcacc aatcccataa aagcgcaaaa
     3841 ctttagaaat tagtttttct tcagaaggaa aacgttcctc tagtaaagga cgtacttgtt
     3901 ccacaaacat tggtttcaac tcattaggcg gaccgggaag aaggatatac gcatgtgtat
     3961 ctgtttgata aaaagtccct aaagcaagcc ctgtacgatt tggtagagga accccgcctt
     4021 cgataatctg ggactgttgc agattgtttt tggtcatttt tcgatgggtt gtttcaaaat
     4081 atgccaataa ttttttgtat ccttccgtat tttgtatgag agacttaccg aggtgagccg
     4141 cagttgcttc ttttgtcagg tcatcttctg tcggtcctaa tccgccacat aagagtatga
     4201 gttcacttct tgtttcagct agagcaatca actcttctaa acgctgctga ttatctccta
     4261 caactgtttg ataataaact tcgataccta gatcagctag ctgttctgac aagaaagtgg
     4321 cattcgtatt cacgacttgt cctagtaaaa gttctgttcc gacagctatt atttctgctt
     4381 tcattacttc ccgctccctt atatagtata cgctgtattt ttatattttt ttatttaaaa
     4441 agagggcaag gagctgtgac aaaaatcttg tcacagctcc ttgttccaaa taaacagtgt
     4501 tctcctgcca aaacctcggt cataagtcac aatatacata aaacatgaaa agctgttttt
     4561 tgaaattatc ccttgtgact cagagttaga cggcaggctc acaacctctc cactaaacga
     4621 tacttacatt gatcctttga acacaccgct gtttttgatg aagtaatcca cacctgaata
     4681 gatagtaaag atcagacaag cataaagcat gatttgatct actggaatac cgatcaggct
     4741 gaatgggata ttattgataa acagcaagat aatagcaacc atttgtgtag ccgtcttgac
     4801 ttttcccggc caagctgcag ccatgacttc tccatgttcg acaagtagta aacgcaagcc
     4861 tgtgacggct aattcacgac agacaatgat cgctactacc caaccagggg cctttccttg
     4921 gtcaaccaac atgataaaag cagtcataac tagcatttta tctgccaacg ggtccgcaaa
     4981 cttgccaaaa ttagtgacaa ggcctcgcgc acgggcaatt tttccatcta accagtctgt
     5041 gatactagct aaagcaaaaa taactgcacc tactagctgt gtgacagcca gtgtggtgtc
     5101 tcctacgtta aattgtcccc aatctaaagg taaacctaca accaaaatga aaatcgggat
     5161 catacaaatt ctaagtacag ttaatttatt tggtaaattc acactatcga ctcctttctt
     5221 ccctattcta cgtgactatc agcgaagttt ccaccgatat tatttacttt tccaaatgaa
     5281 tttattcaaa ggagtatttt tattgaaatt gatctttttg aattaacgaa gaaggaccgc
     5341 gacacagatt tgtcacgatc cttctttttt atacctacaa gtaaacagat gcgtaaacta
     5401 atttatacga tcattctgcg tattgaagag taaggttcac attttttgga ctctgattgt
     5461 tttcccctgg attaactggt acggattctc cattcgcttt gatcgttgca ttgcttgctg
     5521 caccaatcgt gatggtcgca tttgttgctg tttccggtaa cacggtactc tgtgtttcat
     5581 ttgctgccag tgtcccttga taaacatagg cattgtctac tagcacacct aaccatacac
     5641 gattgacagc agtaaattca agggttacag gcttggtagc gtctgtgata tttactgcga
     5701 tggcactgcc agaatcttct cctgtagcta ttgccatttt cttttcttca cttgattttg
     5761 ttgttgattc tactgtagaa gactctttgg tctgcgtgct ttgctctgag gaagaggact
     5821 cctcgactga tccttctact ttaagcgaag aagctgtgtc tccgattatt ggatcagctt
     5881 gacgatcttg ccaagtcata tagcccacga caacgacaat cgccaaagca accaatccta
     5941 ataaaatgac aggaagactt gtccaaaagc gacttggatg cgattcttcc tgatgcattg
     6001 cttttctaga agtacttact gtttcaggct gcggacgttc agggaccgat cctgtcaatt
     6061 tgcttttccc atcaaaaaca tcgactaaat ggtctccatc ttctcctaca gcttcagcgt
     6121 attgccgaat aaatgcccgc acgtaaaatt taccaggcaa ttggtcaaaa tcatcattgt
     6181 cgattgcttc caaataacgt ttttgaattt ttgtaatctg ctgtaattca tctaaagata
     6241 tttttttatt caggcgtgct tgccgtaatt tttctccgat ggtttcaaaa gccactcgtt
     6301 catcttctcc agtctgtttg attctccgaa gcatctgctg ttgcaacgaa agacgttatg
     6361 tttgggtgct gtgacaaaag tcatgtcaca gctccttttt tccgaataaa cattgttctc
     6421 ctgccaactc ctcggtcaca agtcacaata tccaataaat ataagaagct gttttttgaa
     6481 cttgttcctt gtgactcgga gttaaacggc aggctcacga cctctttctt aaacggtgtt
     6541 caatcagctg ttcctcggta ttagctcaaa aaccggcaaa atataaggag atatttttcc
     6601 gtatgtttct ctaatactca ggtcaaaacg ctgatttcac aacctcttcc ttaaacggtg
     6661 ttcaaaagct tgcatctgcg gtaataagtc caaccaagtt aaaaacatta agaagctgtt
     6721 tttacttggc tgttcttatt acttgatgca gggcagcttt ttcacaacct cttggtacac
     6781 ggtgttccag aagtagcttc ttcggcaata agccgaaata tcacaaaaat ttgagaagca
     6841 attttcgtaa attccttctt atttcttgaa gctgaccact tctgtcacaa cctctttgat
     6901 tacttcgttt gattttattt taatataagt tgattaaaag agagcatgat ttgttttatt
     6961 ttctcactaa tttttccaac acaactaaga ataccataaa agctgatttt ggaggaggtt
     7021 cctactacaa gtctaaaacg aaatttaaga cttttcctca taaaatactg gtttattttg
     7081 gtctcatgta aaactcgctg aaggcctctt cacttataaa tgcttcccca gctgccagta
     7141 cgtctttcat ttggatcgaa tcgatgattt caggaagatc aaataaagtt cgatcgccaa
     7201 ataaactttg cgtaaattga ttggcaatat attcgatcga atttaatgat tggaaatatt
     7261 gtccaagcat tttcttcttc agcaaatcga gatttgtttc tgacacttcc ggatcatcag
     7321 cgaatccaag aatgatttct ttgacttttt ctgctgcttt ctctggttcg tccgtatctc
     7381 cgctgaagtc cgcaaagtga aattcacgat ccaagctgaa ttcaaaacca aagctgtcat
     7441 cgataattcc ttgattgtac atcgctagat agtttcgaga agtattgcct aaaatcattt
     7501 ggaacaacag attgattgct gttttatagc gtaacagttc tgttccttct tgcggcaatg
     7561 tgtctaatcc tttaatacca agtacaaatt tatctcgtgt aatggctgct tccaatgcac
     7621 tttgtttgat gatttctttt gtgttttcag ggaaataacg tacaatttct tgctttggag
     7681 ggaaattttt tgcttcttgg ttttcccgaa taagtttcat caatttctca ggctccatct
     7741 taccaactac aaataaaacc atattgcttg gctgataaaa cgtccgatag cacgtataca
     7801 agtcttgagc tgtgattttg tcgatacttt caaccgtgcc cgcaatatcg atatgcaatg
     7861 ggtgtgtagg atacaagtta tttagtatgc caaaaaacat ccgccagtta gggtcgtctt
     7921 catacatttg gatttcctga ccgatgattc ctttttcctt gtttacagtt tcttctgtga
     7981 agtaaggtgc ttgtacaaaa tcgatcagag tcgtcagatt cttttctacc tgatccgtcg
     8041 tagaaaacag atagctggtt ttcgtaaaac ttgtgaaagc attggcggaa gctccttgtt
     8101 tcccaaataa ttgaaagaca tcaccatctt ctttttcaaa caacttatgt tctaaaaaat
     8161 gggcaattcc atctggaact ttcacctttt ctttttcacc atagggaata aattcgttat
     8221 cgatcgaacc ataattcgta ctgaacaaac catatgtctt gtgatagtca tttttaggca
     8281 acaaatacac ggtcaaaccg tttggcagta cttcatgata aagtgtttca ttgatttgct
     8341 catattctgt tttattcatt tgcatttcct cctgctaaaa agaagattgc ctgcaattcg
     8401 atttgctcag ctacttgttg tatctctttg atcgttacgc tctccatacg tttcaaccat
     8461 tcttcatcag ataattttgt ttccggcagc cagctgtcca aaaaagaagc ttcgattgcc
     8521 gcttgcggag agtctagaga aagcagatat tggtttctca gcattgcttt tgtctgagac
     8581 agttccaact ctgttatttc accatttcgc aaactttcta attgctcgtg aatcagatga
     8641 agtacttgat ttcggttctt ttcatcgata ccggtttgga cactcatgaa tcctcggaac
     8701 gtatccacgc tactagaggc ataataagct agactttctt tctctctgac attcatgaaa
     8761 agtttagagt gaggaaaacc gccaaataaa ccgttaaaga ccattagcgc aaaacgttct
     8821 ggttcatcgt aatacacatt tgtctgataa gctaggttca gctttgcttg aacgattggc
     8881 tcacgtactt gtcgttcctt cacgatattc acttgaggtt gggtataaaa cagatctgga
     8941 taaactgttt cccgcgactc aaatggtaat tgcccaactg cttcagctgc tttgtccgga
     9001 tcaacatcgc cgacaacaaa aatgtcgatt tgatcatttg ccatcatttc ttgatagtag
     9061 gacgctagcg aactagcagt gatcttgtcc aaatcttcga ctacgcccaa ccctgggatc
     9121 ttttgttccg ggctgttttc aaaataaagt tcttgcaagg cataggaagc aaaagtttgt
     9181 ttatcttcct tcaaactttc caaatataga cgcagattgt tcttttccaa gtcaaacgtc
     9241 aactgatcaa actgatgatt tttaatattt ggataaaata aaacctcttt taaaaaatct
     9301 accgcttgag aaaaaaggtt tggatcattg acatattcac cattcacaaa actgatccct
     9361 gcgtttagcc aatgtaaatt tccttttttt ctaactgata atccaaagct tgcgccataa
     9421 agctctgcaa gttgcgcact taactttgtc tgatccggat aattcaaact atttgtttcc
     9481 aacatgctgc tgagaagtga acgtttcgtg atgacttctt gttgcagacg cgcagtaaaa
     9541 cggataaaaa tccggatcgt tttgtattgt tttgttggta agacatgaag attcacgcct
     9601 tctgccaatt gatacaccat atttatatgc tccttttcac agttgattgc ccgcttactc
     9661 ttttaatggg tcaacctgcc ttttttactt attcctctgc ttgaaattta taagttcagg
     9721 caattcgccg ttttttctaa atgatgttac actttatagt atagcataga tgttttttat
     9781 caaaagaaac agacggctaa aagcgtatat tgttttttta ttttttattt ttcgatatac
     9841 taaagacaaa taaaagaagg gagggtcatt catgatcaaa gaattcaaag agttcatcat
     9901 gcgtggagat gtcttggatc ttgctgtcgg cgttgttatt ggtagtgcgt ttacaagcat
     9961 cgtaaaccaa gtggtgcaag gcttgatcac accactaata ggttggtttg tcgcaatgat
    10021 cacaggtact tctgatttag aaggagcact ttcaattctt gactggtcgc cgacaaaagg
    10081 cgtcacattt gcgtttggta acgttattag tgctatcatt acatttctga tcactggttt
    10141 tgtcttattc ttagttgtca aagcggcaaa ccgtgcgaag aatttacgct ccaaagaaga
    10201 gcaagtggaa gtggaagaaa ctcctactgc agaagattat cttagtgaca tacgcgatct
    10261 tcttgccaaa caagtggcag aagacaatac acatccagta gagcaaacaa atctttccga
    10321 tacttctaaa taataaagaa tctaaaaaaa agaaagccga ttttcagtgt cggctttctt
    10381 tttttagatt cttaacttgc tacttgttcc tttttcatgt cgatatgtgg aatatcatct
    10441 tccaaataca catctgagat tgccttgaat ccaaacgact cataaaaagc ttgtaggtat
    10501 tcttgtgcgc cgatcacgat tggtttttct ggaaaatttt tctggatcat gttaatcgtt
    10561 tcttgaacaa tctttcttcc taaaccatct ttacggttgt cctgatgaac aaggacacgt
    10621 ccaaaatgga tactctccgc ttcttcatat actcgcgtgt aggcaaggat cttcccatca
    10681 gtatcttgaa aaaacgtatg ccaagcttgt ccatcaatgt catcaacttc ttgataagga
    10741 cactgttgtt ccacaacaaa aactgcgatt cgttctttga cgatcgcgta aaactctgct
    10801 gttgacaatt cttcaaattt ctttacctga tattccacta agcaaacgcc ccctgctttt
    10861 ttattcttag cataccgatt cgcacacaaa aaagcaaacg aaccttacga atctcaggct
    10921 cgtttgcttt ttaaactgct tcagttaaaa attcgatctc aactgtccga gtaagtacat
    10981 ctgaatagct gtaagatact cgttcaaaag aattttcttc aggatccaaa tcaacaacga
    11041 atactgaagg ataggtttct gttaaaacgc cgcggcgttc tgtttgacgc tttcttcctg
    11101 tctgagcaac caacatgatt gggctgccga tacgaccttc taaatctttc ttgattgaag
    11161 ctaaagttgt tggcatacag ttcacctcta ctatcaacta taccacatat ttttaaaatt
    11221 ttcaagttta ccataaaaaa aaagaaatgc aataaaaata aataagaagc tcattaagat
    11281 ttttctaaat tattcctcat tataaaattt caagtgtttt tttattttga gttttactct
    11341 cccgtaagcg ctcattactt gcttgtgatc cattgctaaa cattcagcca tgtctacaaa
    11401 atcaacgcct tgcatataat aatgaaaaat tttagcttct atttttgaaa actggatttc
    11461 gcaattttcg attgcttctt ttaataaaag atgctgaatc gctaaaggtt cttgcaatgt
    11521 gatctctgct aaaaagtctg gtccttctgt ctctattttt tggtcgattg agacttcatc
    11581 tttttgatca cgacgcttca gcgcgttctg cttcctcaac agagaataga tttgattgct
    11641 tataatgctt ttataataac ttccaaagct aacacctttg cttttttcgt aagttctcaa
    11701 tgcctgatat aaagcgatcc ttgcttcttg ttcccaatcc tcagaaacat aatttcttaa
    11761 ataataggtg tttttcaaac gtagtaaaag tggaaaatat ttttgataca gggcagcaaa
    11821 tgcttcttcg tcaccattac gtgcagcgcg caataactcc tcagacataa aataattcct
    11881 ccataaattc gtttatggag gaatcttatc atcaatgatt catcgaactg attagaacga
    11941 tatgttattt attttttctc attaaatcgt ccaatttttg ggacaatttt tttaactgct
    12001 cttcattcca tggagaatta cgtcggaaat caataaaatg catatcttta ttttcttggg
    12061 ctattgtttt ttccgttttt tttatcgtct tatataattc ataagcagaa gttcgtaatg
    12121 ctccttggga aaagatcatc cactgttctg ctaaatcgct tgtcgccact gtcacttgtg
    12181 tcaaacggtc attcagctga ccagcgattc tctcgatata actgtcagcc gtttcgtctt
    12241 ctttcgtaaa aacaacatcc aactggtatt tcttataatt ttgttggatg cccggaacta
    12301 gttgggcatc gaagacaacg atgacttcca ttccttcata tttcgcataa tttgataaac
    12361 gatgtaaaag agcttctctt gcatccgcca ttttgtcctg ctttttaagc tggacaagtt
    12421 ccggccacga accaatcatg ttgtagccgt ctacaatcaa cagctgtttt ttcatggtct
    12481 actccccctg acgttgggaa aaagcctgat acataagcaa accagcagca acactggcat
    12541 ttaagctctg gacgtgcccg gtcatcggga tcgtcagcaa ttcatccatt tcttttttca
    12601 atcctggact cattcctttg ccttcattac caatgactaa agcaattgat cctttggcat
    12661 tccatttttg gaagtttgtg ccggtcatat ctgtgccaaa tacccaaaat cctgtttctt
    12721 tgagctgttg cacagcttgt accaaattcg tcacgcgtgc aacagggaca tgttcgactg
    12781 ccccagtgga agtctttgtt acgataggtg tgattccaac tgctcggtgt tttggtatga
    12841 tcacaccatc gacgccactt gcgtctgctg tccgtaaaat cgacccaaaa ttgtgtggat
    12901 cttcgatgct atccaaaatc aaaaagaagg ggtcttcttt tttctctttt gttcgttcaa
    12961 tcagttggtc aagggataaa tattcataag gtgtaatcgc aagaacgact ccttgatgca
    13021 cgccgtgatc gctcaaagtt tctaattttt gtttaggaac ccatttgact ggcacagctt
    13081 gttcacgtgc gatttctttc agttcttcta ctttttctcc tcgtgaatct tcttgaagaa
    13141 agagtttatt ccctcgccct tgttgtagcg cttctactgc ggcatggtgc ccaaagacga
    13201 aattatcttc taatgcttct tcattttgat cagaaactga ctgatttcgt ccagtttgct
    13261 ttttatttga atatctattt tgttttttgt cttcaaatcc acgtttcgat tgatgtttgt
    13321 ttgttctttc tttacccatt tttttcacca actttctgaa tacaccagcg gatcaattct
    13381 tccatccgct cggtttgttt tgtcaaatgc agatagccca tgagcgcttc gaaccctgtt
    13441 gcgacccgat acgtcgtaac atcagcattt tttgcgctcg tatggctttt agcatttctt
    13501 cctctgcgat aataaagttc ttcttcttct gtcaaaagat gttcttccag catttgctga
    13561 atcaaaaagg cttgtgcatt cgcagaaaca taattcgttg ccgcacgatg cagcttattg
    13621 ggttttgttt ctccttgatc aatcaggtgg tcacgaacat agatttcgta aatcgcatct
    13681 ccaacataag ccaaggctaa accgttcaat tgtgtgtaat ctctcatgct tctcttctcc
    13741 atcgggttcc ttgcggtgta tcttctaata agatcccttt ttctttcaac aaatcacgaa
    13801 tttcgtcgct tcggacaaaa tcacgattgc ttcttgcttg atttcgttct tcgatcaatt
    13861 gttcaatctc ttcatctaat aactcttctg ctgtaaataa aataccgaag atcgaaagcc
    13921 attgcgagaa taaagcttct ccttgtgcca agacagcggc agaaactttc ggctggtcta
    13981 gataagtgtt cagccactta gcaagctcat agaccactgt gatcccattt gctgcattaa
    14041 aatcatcgtc catttcttcg atgaatcgct gttctaaatt ttctaacaaa gcgattttat
    14101 ccgcatcatc tgccaaattc tctgaggcag tttcttggcg gaatttcaaa ttgtcaaacg
    14161 tattcttcag tcgttgtaaa ttggtggctg cttctttcat cgtcgtttca ctgtagcgga
    14221 tcggacgacg gtattgtgtg gtcgccatga agaaacgcaa gacttgtgga tcaacgtttt
    14281 tgatcatttc atgtacagtg atgaaattcc ctagagattt actcattttt tcatcgtctt
    14341 cgccaatcgt tacatagcca ttgtgcatcc agtaattagc gaattttttc cctgttttcg
    14401 cttcactttg tgcgatttca ttttcatgat gaggaaattc taaatcttgc ccgccaccat
    14461 ggatatcgat cgtttctcct aaatgttttg ttgccataac ggaacattca atatgccaac
    14521 cgggacgtcc tttgccccat ggtgaatccc aagaaatctc gccaggtttt gcttgtttcc
    14581 ataaagcgaa atctaatggg tcttcttttt gctgctgttc ttcccctgta cgctgacttg
    14641 ctccgacttc cagttcatcg atggattggt cacttaattt cccataattt tcaaatttac
    14701 gggtacggta atacacatca cctgaagatt cataagcata gcctttttca accaacactt
    14761 gaataaatgc taaaatatct ggcatatgat ccatgactct tggatgcagt gtagcaggct
    14821 cgacattcaa cgctttcgta tcttcttcaa atgctcggat gaaacgatca gcaacttctg
    14881 gtgctgtaat acctaattcg tttgctgtac ggatgatttt atcgtctaca tccgtgaaat
    14941 tcgatacgaa atcgacttta tagcctcgat attcaaaata gcgtcgaatt gtatcgaaag
    15001 caatggtgct acgagcattt ccgatatgga tataattata cacagtcggt ccgcagacat
    15061 acataccgac atgtcccttt tgtataggga tgaattcttc tttttttctg gtcaatgtat
    15121 tgtagatttt tatcattctg atctcctcac tttttctcct ttgattcgaa cgacttttgc
    15181 tggtactcct accgctgtag cgtcgtctgg aacatctttc aacacaacgg cacctgcacc
    15241 gattttggcg ttttttccga tcgttaccgg tcctaatatc tgcgcattcg cagagagcat
    15301 ggctccttgt ttaacagttg ggtgtctttt acccgtttct tttcctgtgc cgcctaatgt
    15361 tacgccatgg aataaaatca catcgtcctc gatttctgcg gtttcgccaa tgacgattcc
    15421 cattccatgg tcgatgaaca cgccagttcc aatcgttgct cctggatgga tctcaacacc
    15481 agttaggaaa cgccagaatt gagcattgat cttcgccaat aaaaagagcc ggtgctgata
    15541 taaaaaatga gagaaacgat gccaaaacaa ggcatgaaaa ccagggtatg tcaaaacgat
    15601 ctcagctgtc gaacgtgcag ccggatcgtt tctctttgct gcatcaatcg ctcgggtaaa
    15661 ccaactcatg actttccact cctttcgtaa gaattttatg taggaaatca tcttcttata
    15721 aagaaaagaa gcgcctttta aataagtttc cttatcaaaa gacgctttcc gcgtggttcc
    15781 acttttcttc ataatcaatg attatctctg acagctaacg cctgttatac gttcttggct
    15841 actttgtttc ctataaaaca gtttttcctg ttttctgtgt ttcgccaaga ccactcccag
    15901 aggcatttcg gcaaccattc attgatacct tgcaccaccc ggtatctctc ttgtaatgat
    15961 cagctgctta cttttttctg ttcatcgtgt ttagttcagt acttgattta aatgtgctaa
    16021 tgatttttca cgaccaagca attcgatcgt ttcaggcaat tctggaccat gcatttgtcc
    16081 tgatacagct acacggattg gcatgaaaag attttttcct tttacgccag tttctttttg
    16141 aacagctttg atggcagctt tgacagttgg agcatctact acttccattt gttctagctg
    16201 tgctttgaat gcgtggagaa cagtaggaac tgtttcacca gcaagtactt cttttgctgc
    16261 ttcattcaat acaggatgtt cattgaaaaa tagcgtagac agatcaacga tttctgcagc
    16321 atagctcatt tgaggttgat acaggctaac gatcttcttc acccattcga ttgtcttttc
    16381 atctgggttt tctgctacac gtccatcagc gattagataa ggcagacaca tgtcagtaaa
    16441 tgcatctaga tccattgctt tgatgtaatg gttgtttacc cattgcagtt ttttcgcatc
    16501 gaaagctgcg ggtgatttac ttaggcgttt tggatcgaac attttgatca attcttggtg
    16561 ttcgaagatt tcgtcttcgc ccacaggtga ccagcccaat aatgcaataa agttgaacat
    16621 tgcatctggt agatagccta attcgcgata ttgttcgata aattgcaaga ttgattcgtc
    16681 acgtttgctt agttttttac ctgtttcact gttgatgatc aatgtcatat gtccgaaggt
    16741 tggtggtgtc cagccaaatg cttcatagat catcagttgt tttggtgtat tggcaatatg
    16801 gtcatctcca cgtaaaacgt gagtgatttt catcaaatga tcatcgaccg caacagcaaa
    16861 attataagtt ggcataccat cgcgtttttg tatgacaaag tcgccaccga tattatcgga
    16921 ttcgaacgaa atagcgcctt tcaccatatc tgtaaatgcg tattctgtat tgcgaggcac
    16981 acggaaacgt acaacagatt ctagaccttg tgcttctttt tctgcttgtt cttcaggtgt
    17041 caagttcgca catgttcctg cgtaatgagg catttctcct cttgcgcgtt gtgcttcccg
    17101 ttctgcttct aattcttctt ctgtgcaata gcatttgtat gctcgattgc tagcaagcag
    17161 ctgatcaatc agcggttgat agatttcttt acgttcagat tgacggtaag ggccgtattc
    17221 tccaggattt tcaggagatt catcccaatt cattcccaac caagcaaggt tttccaactg
    17281 gcttttttcg ccatcttcga tattacgttt ttggtcagta tcctcaatac gaataataaa
    17341 gtctccatca ttgtggcggg caaacaaata attgaataat gcagttcttg catttccaat
    17401 atgcaggtgc ccagttggac ttggtgcata gcgtacgcgt actttcgtca ttttcttcct
    17461 cttctttcaa actagacttt gactaacagc aaaaattccg tcagttacgg cttctcaaat
    17521 atcatttatt taaagccact cagcacaaat tttacctttt ctaaggtaaa tagtaaagcc
    17581 aactggttga atttccttac cagttggctg aatttctttt ttattttgat tgtttagtct
    17641 ttttctctgt ctctttttta ttgtcgattc ctcgtcctgc atgtgcaggt ttagcaaaga
    17701 tcatgcgtcc agcagctgtt tgaagggcac ttgttacaac gacttcgata cgttcattca
    17761 tgtaatgctg tccatcttct acgacaacca tcgtgccgtc atcaaggtag gctactcctt
    17821 gttggcgttc tgtcccggct tttactacta gaacattcat cgtttcacca gggatgacga
    17881 ctggttttac ggcatttgcc aacgcattga tattaagaac aggtacattt tggaattcag
    17941 agactttatt caagttatag tcattggtta caatgacacc atctaaaagc ttagccaatt
    18001 tgatcaattt gctgtctact tcactgatat cttcaaagtc tccatcgtac atttcgacag
    18061 atataccctc ttctttttgc aaggcattta ggatatctaa tccgcgacga ccacgcacac
    18121 gtttcaaact atcccctgag tccgcgatgt attgtagttc gtaaagaaca aaattaggga
    18181 tcatcaaggt tccttctaag aatccagtct ttgtaatatc ataaatccga ccgtcaatga
    18241 tcacgcttgt atccaagatt ttatatttat ggaaattttc tcctgatttt cgttctaaca
    18301 gttgactctc aacttgacta gctgtttctt gctcgatttt tttgcttcgt gaaccaaaaa
    18361 ctttcttcca ttcttcgatt cgtgtcgttc ccattctcaa tcccagatag cctaagatga
    18421 tcatcagtaa aatcggcaat acactattga cgaatggaat ttccatattg taaagagggg
    18481 tcgagatcac aacacctaaa gtcaatccga tgatcgcacc gatcgcaccg aagagaagat
    18541 aagtcaagct gacctcactt agtttttgtt ctacttgttt gataatagct gagatatgtt
    18601 tggccaacag caaagataat aaaaagaaaa taagtgcgcc taacaggctg ttggtaaatg
    18661 tattattcag ccatccgttt gactgttgac cgattgcctg ccaagctgag ggtaaaaatg
    18721 aaatacccaa gcttgcgccg acaatgatca tcagcaaagt aatgacacgt ttttgcatcg
    18781 tttttcctcc gtttcgacaa tcatttatta gttagcggaa cacacgcttc aacgtttcag
    18841 ccaaagttgc tactccaact atctcgattc cttttggcgc ttcccagtta cctaagttgt
    18901 ttttaggtag gtatactttt gtgaagccga gtttttggac ttctttgact cgttgttcaa
    18961 tatgactgac acgtctgatt tctccagtca gtccaatttc accgatgaaa cattccgttg
    19021 gctgtgttcc tttttcttta tagcttgaag caatactgac agcgatagct aaatcaatcg
    19081 ctggttcatt taattttacc ccacctgcag cttttaagta agcatcttga ttctgaagaa
    19141 gcaacccagc tcttttttcc agcactgcca tgatcagaga tacccgattg aaatcaagac
    19201 ctgttgttgt tcgtttggca tttccgaaca tagtaggtgt gactaatgct tggatctcta
    19261 ccaaaattgg acgtgtccct tccattgcca caacgatagc agagccagtt gcaccgtcta
    19321 ggcgttcttc taagaaaatc tgtgaaggat tagcgacttc ttccaatcca tgctcatgca
    19381 tttcaaaaat cccaatctca ttcgttgagc caaatcggtt ttttactgct cgcaaaatcc
    19441 gaaaactatg atgttgttca ccttcaaaat ataacaccgt atccaccata tgttctaaca
    19501 ttcttgggcc ggcgatcgag ccttctttgg taacatgacc gacgataaaa atggctatcc
    19561 catttgtttt agcgattttg agtagttctg cagtggtttc tcttacttgg ctgacacttc
    19621 ctgccacact tgtgatgtct ggctgcgtca tcgtttggat ggaatcaatg ataacataat
    19681 caggggagat atgttcgatg gcacgactga tttcgttcat atctgtttca gcgtatagat
    19741 aaaattctgt gttgatactt ccgaggcgtt ccgcgcgtaa ttttatctgc tctgcgcttt
    19801 cttcgccgga tacatataag acttttccgc ctatggctgc taattgctga gaaacttgta
    19861 acagcaaagt ggatttcccg atacctggat cgccaccaat caagaccata gaccctggca
    19921 ccacacctcc gcctaacaca cggttcagtt cttctaattt tgttttgatc cgaggttctt
    19981 ttttagggac gacgtctgcg atttttgttg gttttgcttt ttctcctgtc aaacttgtcc
    20041 gagttctgcg gtccgttgta tcttgttcga tttcttcgac catcgtattc cattttccgc
    20101 aatttgggca gcgtcccaag aacttaggcg acacataccc gcaattttgg caaacaaatt
    20161 gtacttttga tttttttgcc attgtaccgc ctccttttat cctaatcatg agacattaaa
    20221 tcaagcttaa gtatctttaa cgttttattt actggaagaa ccaaatccgc cttgacgttg
    20281 agcagtcgtt tgatcttgat ctgcttttaa aaacggcaaa aagatccctt ggccgatacg
    20341 ctcgcctttt ttgatcacta catccttgaa accaaagttg gtgaattgga acatgatatg
    20401 gccttcattt gcctcattat tgtaataatc actgtcaatc acacctactc cgtttgtcaa
    20461 cactaaaaac cgcttcaacg gattgcttga acggttagca agctgcaaaa attcatcttc
    20521 tcccatgtaa gctttgattc cagtaggcac gagggttggt ttcaattgtt tttcattttc
    20581 tgatacatct tttttcaatc catctgcgac tgtttccaac ccctttttcc agcctgcttt
    20641 ccagatactt ggaatcacga cctcttctgc tgcttcaaaa tcatagccag cagcatgatg
    20701 tgtagcgcgc tgcggtagat tgatattttg atctttatat ttagaaataa cttcaaatcc
    20761 tctttttctc accggttttc ct
//
LOCUS       DACBZK010000046        20663 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.048, whole genome shotgun sequence.
ACCESSION   DACBZK010000046 DACBZK010000000
VERSION     DACBZK010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20663
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.048"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            168..362
                     /locus_tag="IVD66_001793"
     CDS             168..362
                     /locus_tag="IVD66_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146013.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..929
                     /locus_tag="IVD66_001794"
                     /pseudo
     CDS             631..929
                     /locus_tag="IVD66_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1026..1460)
                     /locus_tag="IVD66_001795"
     CDS             complement(1026..1460)
                     /locus_tag="IVD66_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6146014.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1692..2402)
                     /locus_tag="IVD66_001796"
     CDS             complement(1692..2402)
                     /locus_tag="IVD66_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAP6146015.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2392..3252)
                     /locus_tag="IVD66_001797"
     CDS             complement(2392..3252)
                     /locus_tag="IVD66_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HAP6146016.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3257..3895)
                     /locus_tag="IVD66_001798"
     CDS             complement(3257..3895)
                     /locus_tag="IVD66_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HAP6146017.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3910..4209)
                     /locus_tag="IVD66_001799"
     CDS             complement(3910..4209)
                     /locus_tag="IVD66_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6146018.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4252..5736)
                     /locus_tag="IVD66_001800"
     CDS             complement(4252..5736)
                     /locus_tag="IVD66_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAP6146019.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5756..6217)
                     /locus_tag="IVD66_001801"
     CDS             complement(5756..6217)
                     /locus_tag="IVD66_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP6146020.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6235..7302)
                     /gene="ulaG"
                     /locus_tag="IVD66_001802"
     CDS             complement(6235..7302)
                     /gene="ulaG"
                     /locus_tag="IVD66_001802"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HAP6146021.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7520..8290
                     /locus_tag="IVD66_001803"
     CDS             7520..8290
                     /locus_tag="IVD66_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP6146022.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8563..9390)
                     /locus_tag="IVD66_001804"
     CDS             complement(8563..9390)
                     /locus_tag="IVD66_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6146023.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9958..11193
                     /locus_tag="IVD66_001805"
     CDS             9958..11193
                     /locus_tag="IVD66_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAP6146024.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12192..12452)
                     /locus_tag="IVD66_001806"
     CDS             complement(12192..12452)
                     /locus_tag="IVD66_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAP6146025.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12479..13780)
                     /locus_tag="IVD66_001807"
     CDS             complement(12479..13780)
                     /locus_tag="IVD66_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6146026.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14072..14530)
                     /locus_tag="IVD66_001808"
     CDS             complement(14072..14530)
                     /locus_tag="IVD66_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAP6146027.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14543..15868)
                     /locus_tag="IVD66_001809"
     CDS             complement(14543..15868)
                     /locus_tag="IVD66_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HAP6146028.1"
                     /translation="MKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDEER
                     NMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGRDFVFSQIRVGGLEMREKDEKIPL
                     KHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVRRK
                     YPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREIMP
                     EIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVVEH
                     TDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLNDDR
                     RRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAVEK
                     LLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15885..17297)
                     /locus_tag="IVD66_001810"
     CDS             complement(15885..17297)
                     /locus_tag="IVD66_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6146029.1"
                     /translation="MNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADDMLNIPVIGAA
                     GNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMDPEVNMGIFGG
                     IISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLGFIWPLIQIGI
                     DNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSPSKEVFRGEMT
                     RFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMGSGAGTSFIAN
                     ITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVDYLINFRIATN
                     AILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEETELGLASKNYE
                     YMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISGIIKPTEKNYQ
                     IIIGLEVTYVMAEFNKLLEE"
     gene            complement(17314..18078)
                     /locus_tag="IVD66_001811"
     CDS             complement(17314..18078)
                     /locus_tag="IVD66_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HAP6146030.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18182..19057)
                     /locus_tag="IVD66_001812"
     CDS             complement(18182..19057)
                     /locus_tag="IVD66_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6146031.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19312..19396)
                     /locus_tag="IVD66_001813"
     tRNA            complement(19312..19396)
                     /locus_tag="IVD66_001813"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19360..19362),aa:Leu,seq:caa)
     gene            complement(19414..19485)
                     /locus_tag="IVD66_001814"
     tRNA            complement(19414..19485)
                     /locus_tag="IVD66_001814"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19451..19453),aa:Gln,seq:ttg)
     gene            complement(19495..19567)
                     /locus_tag="IVD66_001815"
     tRNA            complement(19495..19567)
                     /locus_tag="IVD66_001815"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19532..19534),aa:His,seq:gtg)
     gene            complement(19629..19713)
                     /locus_tag="IVD66_001816"
     tRNA            complement(19629..19713)
                     /locus_tag="IVD66_001816"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19677..19679),aa:Leu,seq:caa)
     gene            complement(19734..19804)
                     /locus_tag="IVD66_001817"
     tRNA            complement(19734..19804)
                     /locus_tag="IVD66_001817"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19770..19772),aa:Cys,seq:gca)
     gene            complement(19850..19921)
                     /locus_tag="IVD66_001818"
     tRNA            complement(19850..19921)
                     /locus_tag="IVD66_001818"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19887..19889),aa:Gln,seq:ttg)
     gene            complement(19933..20005)
                     /locus_tag="IVD66_001819"
     tRNA            complement(19933..20005)
                     /locus_tag="IVD66_001819"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19970..19972),aa:His,seq:gtg)
     gene            complement(20008..20081)
                     /locus_tag="IVD66_001820"
     tRNA            complement(20008..20081)
                     /locus_tag="IVD66_001820"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20047..20049),aa:Trp,seq:cca)
     gene            complement(20088..20168)
                     /locus_tag="IVD66_001821"
     tRNA            complement(20088..20168)
                     /locus_tag="IVD66_001821"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20132..20134),aa:Tyr,seq:gta)
     gene            complement(20170..20245)
                     /locus_tag="IVD66_001822"
     tRNA            complement(20170..20245)
                     /locus_tag="IVD66_001822"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20210..20212),aa:Phe,seq:gaa)
     gene            complement(20281..20353)
                     /locus_tag="IVD66_001823"
     tRNA            complement(20281..20353)
                     /locus_tag="IVD66_001823"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20318..20320),aa:Asp,seq:gtc)
     gene            complement(20363..20435)
                     /locus_tag="IVD66_001824"
     tRNA            complement(20363..20435)
                     /locus_tag="IVD66_001824"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20400..20402),aa:Val,seq:tac)
     gene            complement(20451..20522)
                     /locus_tag="IVD66_001825"
     tRNA            complement(20451..20522)
                     /locus_tag="IVD66_001825"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20487..20489),aa:Glu,seq:ttc)
     gene            complement(20537..20626)
                     /locus_tag="IVD66_001826"
     tRNA            complement(20537..20626)
                     /locus_tag="IVD66_001826"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20590..20592),aa:Ser,seq:gga)
BASE COUNT         6529 a         4319 c         3276 g         6539 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa tcatgtgttc attttttata ttagttcgaa tttgcaaaaa attgtatttg
      901 ataaagaggt gagtaaaaaa ataaaatagc tgagcattgg aggatagatt gagtgatact
      961 aagtctatcc tcttgttttt ctaaagaact aagctagaat tttttctttt gtacgttatt
     1021 atatgttatt tgtcattacc aaaaagcacc ttttttcttc tagtatctat gacataagaa
     1081 ataccaccca tttcctttac ttgaacaaat cctactgatt cataaaattt ttttgttttc
     1141 tcagtatcat ctgtcaataa ttcgatttgg actggtccat aactagtgat cttctccaaa
     1201 gcttcattca aaagcacttt gcctattcct tggcgctgat acctcggatg aatgaggata
     1261 tcttgaataa atgcgatcgt cgcaaaatca gtgatccaac gaacgattcc gataatcttc
     1321 ccttccccat tacgctttat cagagattca gattgttcaa atgctctagc taaccttgca
     1381 gtgtcttttg tgtaattcgt ccaaccaacg ctcttatata attcagaaat ctcatcgatc
     1441 ataagggaat caatattcat ttttttcttc ctttcttata caattctccc tctaataata
     1501 cagttctttg actatttaat ctatcacata taactctcct gtaaagattc tctcgattcc
     1561 ttaaaattcc tctttccttt tagaatgcat actttttgat aaataaaaag gttgtgataa
     1621 attttcttca caacctctgt ttctctctat caagtgttat cttttaattt tctaccctta
     1681 ccctagcatc tctattgccc gtagtatgca tactttccat gtttgcgaaa ataatgttta
     1741 tctagtaaat attgcgggat ttcacatata ttggggttga tcagctcgtt ttctttggcc
     1801 atcagacaaa tttcatctaa gatcaaactg ttttctactg ctttcatagg tgaatccccc
     1861 catgtgaacg gtccatgtcc atagacaagt actccaggga cttcgtttgg atctaatttt
     1921 ctttccttaa acgtctcgac aatcacattc cctgtatgaa cttcgtaagc ttctcttact
     1981 tcttctttcg ttaattggcg tgtacaagga accttaccat aaaaagcatc agcatgagtc
     2041 gtgccataag ctggcaaatc gcgtcctgct tgcgcccaca tgacggagtg cgtggaatga
     2101 gtatgagtaa tagcagttat atcttcaaaa gtttgataca aaacaacatg tgtggggaga
     2161 tctgaagatg gttttaagct atcttcttct attatatttc ccgacaaatc tgttaccacc
     2221 atttgatctg cttgcatgca ttcatatctg acaccgcttg gcttaatgac gatgactcct
     2281 agctcacggt ccacttcact cacattgccc caagtcaatt tgactaatcc gtatcgcggc
     2341 aatgccagat ttgcttcaag gacacgttgc ttcattgctg caattttttc ttcacaagac
     2401 atcatagcca gcctccttca atttagaact taagtagtct tttgcctgct ggatttctct
     2461 tcgaaagtct tggctttttt cactccacat ttcaatcaga aatgttccat cataatctag
     2521 acgtttcaaa tgtcttaata atccaagaaa atcaacacaa ccgctaccaa aaggaacatc
     2581 acgaaactgg cctgaatatt cttttgttac agggtaagta tcttttaagt ggatagcagt
     2641 gatataatcg atccctttct caagttctcg agccggatta ttttccggcc atgcggacaa
     2701 attgcctagg tctggatata cttgtagaaa aggtgaatga atctgttctt tgatttctaa
     2761 aaattttgaa atggagttca taaatggatc atccatgatt tccacggaaa gaatgatgcc
     2821 atatttagaa gcttccttta cgctttcttt tattccttcg ataaagtctt ctctggaatt
     2881 cattgatttc tcttcataat aaacatcgta tccagctatt tggattactt tgacgcttag
     2941 attatgcgcc aaatggattg cttttttcat tagttgtttc gctgcttttt tcttttctgg
     3001 atcagcagaa ccaaacggaa atcgccgatg cgcacttaaa caaatcgaat ggatacgtac
     3061 accggagctg aacatctctt ctctcagctc agctatcttt tcttcagacc aatctaatcg
     3121 tgctaaccgc tcatccgtct catcaatcga catctcgata aaatcgaagt ccatttcttt
     3181 tacaagggaa aaacgttctt tccatgaaat atctttgggt aacgcttttt cataaatccc
     3241 aatttgagcc atttccttac ccccagatac gaatgatctc atctttgaag ttttgtgcgg
     3301 ccttcatcgg atcatttgct gctgtaatac cacgaccagt gataaaggta tacacatcga
     3361 tcccttcaaa taagtgtaat gtgtgtggat ttaatccacc agttacagaa acattaaagc
     3421 ctagttcaat cagttttttg atcttcgata aatctttttc accccaagtt tcaccagata
     3481 acagcgcatc acggctttga tggtagatta cctgccggat accgatgtta tgccaatcca
     3541 tggcttgttc aaaagtccaa ttgccgtaga gttctacttg caattcacct atttcttttt
     3601 gtgctgcctc catagttgga atcgttgcac aacaaatgac tgtcatccag tctgctcctg
     3661 cttttgcaac attactcgcc actgttcctc cagcgtctgc acatttcgta tcagcgacta
     3721 gttttttatc tgggaacata ctgcgaatac agcgaatcgc tttttgtcct tcctgtaagc
     3781 aaagaattgt gcccacttca ataatatcta ctacatcacc aactttcata acatctccta
     3841 atgcatgttc taagtcattg tgatctaacg caatttgcaa attcggcctg ctcatcttag
     3901 ttccttcctt tacttgtttt tttggtacca ctttgtttca gcaaattttt cactgatttc
     3961 tttgactgac atcacatttt tgataccgat aactgtaact ccttttttct ctgcctgagt
     4021 aaacatattc aaaaaattga ctggcgtaaa aactacatcg tattggccag ctgaactttt
     4081 tccctctgaa atggcacaat gatggatttt ggtaattggt acgtttagtt ctttcattgc
     4141 tttttccaca cttctcatca tcatcaagct tgttcctgat ccatttgcac acgatactaa
     4201 aattctcatc ttaatccctc cattatgagt gttgtctaat cagattttct tttatactct
     4261 ctgcttttct gcatatgtgt catagtcttc tacaatcaaa aaataaccat caggattttt
     4321 ccgatattgt aactgcggaa tagccaataa accaatgaca actacggcaa ttccagcata
     4381 acctaggact ttcatgatta ctgtaaacaa tggccaagct gttgcccagt cgaacatccc
     4441 gatataacca ccgtatgttg acatcccaat ccatgtagcg aataatgctg aaccgcctac
     4501 ttgtatgatt cctgaaagaa acgggaacag gcaagcggct ttgaatccac ctcggttatt
     4561 ggcataaact gctataacgg cattatcaaa gaacaacgga atgaaaccgg ctatgacgat
     4621 cgttggtgat ttcaataaaa tcagtaaacc aatcatcaaa aactgtccca aagcaccaaa
     4681 caagaaccca atcgttaccg catttggcga accaaagcca aaagtagcag ctacgtcaat
     4741 tcctggaaca gctcctggta aaatcgtgtt tgagattcct tggaaagatt gagttagttc
     4801 atcgacgaat gtccgaacac ctaattgcaa gatcgccaga tataccgcaa aatttaaaga
     4861 agtcgtcata atgtagaata agaaactctg cccttcttgc atgaattgcg cttgaatcaa
     4921 ataatctttg cctagtacaa tcagaatgat cccaaagaaa aatagcatga gtaacgaagt
     4981 agcaaccata ttctcattga aaatcgacaa gaatcctggt aatttgatat cttcaatttt
     5041 tttgtcttgc ttgattgatc tatttttctt ttcatcccgc tttttcatcc actcagctaa
     5101 ttttgcaaat ataaagattc cgaacatttg ctgatgtgcc actgcaaatc cggcaccttc
     5161 tgtcaattcc tgcgtgattc ctactgttaa gttagaagct actgtccaat aacaacctaa
     5221 aatcagtccc ataaaaatca atgcttgtat cctacctaga tcaggaaagc aaaacagtaa
     5281 aatccaaaaa gcggtagctg cttgttgaac ctgaacgttt ccggtagtga aaacggaacg
     5341 cagtttcgta tatttctgaa aacggactaa taagatattt aaaacaaatg caatcagtaa
     5401 taaaatcatc acatctccaa aggtacggcc aaatgtctcc attaatccag catccacagc
     5461 attttgtcca aaataaggat ctgtaaccat ggcatccaaa ttgaaccgtt cctttagtcc
     5521 aaccaagatt ggccgaaaat tattgaccaa accaccagag ccaacagtca aaataaagta
     5581 accgaccgtt gcctttaaga atccagcgat gcattcatga agcgggcgtt tcagcaaaat
     5641 atagcctaat aacacgataa aaccaatcag gtatgctggc tgcgtcaaga tatttgttgc
     5701 aaaatacgtc caaatgctta acaaaaattc ccccatcttt tttctcctct atcaattaat
     5761 tatattctgc catcacaact tggtaatcat cgatggagtt cgtagagatg agacgctcaa
     5821 ccaatccatc tgtcattaat aattcggata atttttggat attttctaga tgttcttctg
     5881 gatcttttgc tgcgagtgta aaaaacaaac tagccgtttt ctcctcattc tccccttcac
     5941 tttcaaaacg gattggctgt ttcaacttgg taaatgaaat agctgttcca aaaacaccat
     6001 cacttttttc tgaagaatgc ggcattgcta cttgaggtgc gatcacaata taaggaccgt
     6061 atttttctac acaatggatg atctcctcca catacgtttc atcaataatt tccttatcga
     6121 tcaatacaag acagctttcg gcgatagctt cacgccaatc cgtgatttct ttatctgggt
     6181 aatgaatcaa ttgatggtca aaaaagtatt tcagcaagaa actccccttc tttcttataa
     6241 aaacgacgga aacggtgtat cattttcaat cgagaagaca tcttcaaatc ctcgataaaa
     6301 attaaactca agatcatctt tgtttgtcgg atagatgaat ttcccgccta cttgccagat
     6361 ataaggttta aatccatact tcaggcgatc ctttttgaat ttccaaattt cagtgatctc
     6421 ttttggatca gccataaaat tagaccaaat atcgtagtgg acaggaatca ctacttttgc
     6481 attcaatgac tccgccatgc gcagcatatc aacagaagta actttgtctg ttatccctcg
     6541 tgggttttca ccataggccc ctaaacagac atcgattttg tgttcattac catgtttggc
     6601 aaataaattg gagtaatgtg aatctcctgc atgataaaga ttccctcctg atgtttcgaa
     6661 taaatagttt actgcaattt gatccatctc ctgaggcatt tttcctttta atacctcttc
     6721 tggatcttca caagtgacca acgctgtccg atcaaacgct tctaaagcta ctacattgat
     6781 gtctttgatt ttgactgcat cacctggctt tactgtaatc gttttttctt caggaattcc
     6841 ccatttttgc cacgtgcgaa ccacttcttt tggcccaatg aatgttgctt caggacaatt
     6901 ttgatgaact gctgcggctg tatggatatc tagatgatcg gaatggatat gtgtaacgat
     6961 taaagcgtct acatttttta tcgcaaaagg atcgattacg aaaggctgag tacgtaaatt
     7021 aggctgcata ttttgaacgc cactcatacg catcatctga tggccttttt tcatcatgcc
     7081 attcccatga ctacgttttc ccgtcccaca ccatagatca cataaaatat tcgttccttc
     7141 atgacttttc agccaaattc ccgtacagcc cagccaccac atagcaaaag ttccaggatc
     7201 cactacttct gtttcgattt cttcattcaa gtatgtgccc cactcaggaa atgtttctac
     7261 taaccacttt tcttttgtta cttcattgac agttttactc atttgcttgc tccccccata
     7321 tcgttgttcc aacttacaag taaatattaa tgtgtatcag catccatgaa aaccctttta
     7381 tatgaccgtt tgttttttat atgattttct ttcagtaatc aatgattgtt tcagtataat
     7441 aaagacagat atgaatgttt aaatgaacaa ctagtcaaat aaatccatgg atcaagatgt
     7501 ccctcaggag gcaaaagtca tgaaaaactc acttgtcaat attgaaaaac gtcaaaaaga
     7561 aattttggaa ctgcttcagc agactgaaca actatcaact ttcgaattag ctgaatccct
     7621 tgatgtatct attagtacga tacgaagaga tttaaattta ttagaagaaa aaaacgagat
     7681 catacgcaat tacggttatt gttcttataa ttacaaaaac cagactgatt ttgatcaatc
     7741 tggtcctgaa aggattaaac aagcgattgc cagagaagct agtaaataca ttaacgatta
     7801 tgatacgctg tttatcaatt ctagctcgac tgcgttgaaa acactggatt ttcttcaatc
     7861 taaccatttg acagtcatta caaacaacgt gaaaatcaat tactctccgc acaaagataa
     7921 ttgtagttat attttaactg gtggagagat gcgctttcca aaagaagcac tagtgggcga
     7981 catcgcatta aatacgattt cttcagtcaa tgcagacatt tgtatcattg gctgtagcgg
     8041 agtcgatgta gtacatgggg tcacaacaaa gatattaaat gaatcaacga tcaacgaaat
     8101 gatggtcaac aagacaatca aatgtaagat tttagtcgct gatcatcgaa aaatcggact
     8161 gacatcaaag ttcaagattg ctgatatttc agtctttgat tatttgatca ctgataaatt
     8221 ttgttctgaa aaagtattag aggagatcag aaatacgggg ataaaaacca ttcaagtaga
     8281 ttcattttaa gaaccaggac gtaaatatgt aaataggatt atcaaaaaaa tgaataacaa
     8341 atttatcgat aaatgaaaaa cacgctacgc tcaaattgat aaaggaatcc caagatgtat
     8401 ccatccaatc gataccatca taatctattg cttcttttat aaccgttata tgttgcctaa
     8461 ataggaatca aacaatatcg aaaaaaggag gtatgacaaa agtcacacct ccttttttcg
     8521 aataaacggt attcaaatca gaacactgat ttcacaacca ctttatttca ggtcgttttc
     8581 aatcaccttt accgcgtaat catttccgtt gaaacgcgct attttttttg cgtccatata
     8641 tctttctaaa taatcatctt ctcctaattg cttatggcaa gaagcaattt cataaagcaa
     8701 gtattccaat gcataagtcg atttatgttt cttattatac tcaataccct tctcacataa
     8761 ttggattgct ttatcataat cctcgatttt acggtaatag gtggcgatat cataatatac
     8821 aatgcagacc atcagattat caaaatcagt ctcactcaat attttaagtg tacgctccac
     8881 ataaactttc gcaaaatcta attctccttt tgacaagtag atcattgcca cgtttgcagc
     8941 tgcttgtaag tgatggatat ctgtttcggt cgtttgttcc aacacttgat taaaataaaa
     9001 taatgctgca tctggttttt tcgcataaag atgatcaagc agtccttgat aaaataaaat
     9061 ttgatttaaa agatcagaat tacttacttt ttcctgatcg atcgtttgta aaattttata
     9121 agattcttgg tattttgata cagaattcaa tgattgaatc tcatttattt ttttcctgat
     9181 tttgtcttct tctgtttcta ctaatatatc ggagatctcg acattcagct ttttgcaaag
     9241 cgcacttaag atattgatgc ctggcgacat attcttgttt tcgatattgc tgacagttgc
     9301 ttgttcacaa atgccttctg ctaattgtac ttgtgttaac ccctttttct ttcggtattc
     9361 ttttagtaat gctccatcta ctttaatcaa aacaatttcc ttccctttaa aaaattattt
     9421 ctcctttata tcatacacaa aaaaaagttc taaacaacca aaaatgttta gaacagaata
     9481 aaaattttaa ttttaaaata atattcaaat taaacaactg gcgtatctgc tccttgattt
     9541 ctttttgtgt tatctgaata attatcgttt acagttataa cacatagtga aaattgtcat
     9601 ggcgagaaag tctaagaata tttttaaaca taactatttc tttcttacgt gtgtataatg
     9661 acgacagcac acctatcaat taatataatt attttatttt tttatgttct catgtttatt
     9721 tttaatgaca caacttctcg tatttatctg gcacaacata taaatcgatc aaaaaattgt
     9781 tgcgtgtttt tttgaaaatt ggagtttcaa cttgattaca aaatttaaat ttagaagttg
     9841 tgaaaacagc gagagacagt ttaatattca aaatatacat aggctactcg aacgctgtgt
     9901 tttttagtat actagtaaga aacgaaggga tagactcatt ccaataagga ggatttcatg
     9961 aagacaattc tttttgctcc tgcagtattc aatttagctg agacaacacg aatgattgag
    10021 gttgccaaag ctatgaaaga ccgttattac tgtgtattct ttggcttttc taaaactttt
    10081 gctcctttga tcacagaaag tggctttgag tatcatttac tagcgccgat ccttacgaaa
    10141 aaacaagaag aacaaatcat aaaatttgac cagttgcgta cacttaaaaa cccttttacc
    10201 aaagaaatgg ttgcctctcg tatcactagt gaacagagtc tgattgctaa gtttgagcct
    10261 cgactgattg tgacaggttc gaatgtgaca atttttttat cggcccgcaa taaaaagatt
    10321 cctttagtat atgttaaacc ctatgctttg agtgaacctt tttttcaatc agagcatgcg
    10381 ctgatgcccc acgagttacg tttcttcggc cctttaagca atcccctttg gcactggaca
    10441 aaaaagcgta tagtaaatac ccgatggatc cccaatgcct tcaaacacgc tgcacaaaaa
    10501 gaaatgcttc ctttaccaaa aacaagttta caaatgatgg atgctgatct aaatctcatc
    10561 acaacgccta aactattttt ggaagaagaa cagctgccgg aaaattatcg aatcgttggt
    10621 ccaatttttg ctaagctcag tacttccttg cctgaagaag tgctaacttt tatacagcga
    10681 aagcaacaag aaagaaaacg tattatctat ttcgcaatgg gtagttcagg caatccgcgt
    10741 atgttacgca aaattttgtt cttcttacaa aaacaaccgg atctagcggt tattgcacct
    10801 attgactatc tgcttgatga cattcaatct gactcagaag atcttttaat aacagaatat
    10861 ctgtctagtc atcttttgca tgaattcatt gatttttctt ttatccacgg cggggaaggg
    10921 accgtccaaa ctgcctgtga atccggcaaa ccgtttatcg gtgtggggat gcaatttgag
    10981 caaagctgta atattgacta ttgtgtaaaa tacggaaacg caatcgccct cacaaaacca
    11041 gtgactgaaa gaaaactgca gattgctctg cgcgaagttt cttcacccaa gattcgtcag
    11101 caggcacgca cgctgcaagc cgtttttcca ataaatggtc cacaacaagc aattcaagaa
    11161 atcgaaacct tcctgagcaa ccacccaata tagtttcaag tagaaaaagc ttttttaata
    11221 gagactcatc agtaatttcg ctattcgaga cccagacagt gaaaatacaa aaaaagtaaa
    11281 tagtggattg aaaagttaga gttacttaaa ttacggtgtc taaaaaacac aaaatcatcc
    11341 ttaaaataaa agatctgacg ctatccaaat gagcataggt agcgtctgcc atttattctt
    11401 agtcaaattc tttgacacct ttctctggtt ggatcatctc aacgtttctt caaaagaaag
    11461 accataataa ttaggcaaat acattttctt aaaatgtgtc atatagatct agaagcatcg
    11521 ctttgtagag atttgtgccg ctagtcccct caacaattac taaatcaaat gtaggattta
    11581 ccactttatc tttgataatc aacctccctc ttctgttgag acaatgatct cgcaatccga
    11641 tgcatactcc tatataaact gccagcaatc cccacatatt gagtagatca tgtcagaatg
    11701 ttctatgtcg tcagcaacga tacactaaaa gtcacgttca ccatgactga ttgctattcc
    11761 cagcacaatt atttctatac acgtttcatg atttgaataa acactcacat catacatatt
    11821 accattcata caccatactg cagcccctac tatatggttg taagctccca aatctatatt
    11881 tgacttgatc actttggtag tagatctact aattctaaat ccattgctga taaaatttcc
    11941 attttttcct ccttctttct gccaaaacag ttaaaacaat aataatcttt atgtaaaaaa
    12001 gggctgtgac aaaagccttg tcacagtccc atattccgaa taaacggtgg tcaaaagctt
    12061 gcatctgcgg taataagttc aaccaaacga aaaataagcc aacatttcac aaaaatttaa
    12121 gaagcaattt tcgtaaattt cttcttattt cttgaagcta accacttctg ttacaaccac
    12181 ttttagaaca tttaaagctt cgatgtgaca aaccatctat gctgctcgat cataaaattg
    12241 atagcaaaaa ttccacaaag tacatatgtc ccccatgaaa acaaaacatt catatgcggt
    12301 acaatgatct ttggaagaat cacgatcaaa aatgatgcca gtgcccaaat ccatcgattg
    12361 atttgaatat gatatgtagc tagcatattc aatataaggt gactagccgt taataaaaag
    12421 ataaaaacaa aaaataaaat cagccaatac attgtttccc accttctaaa aaccaaactt
    12481 agacagtctg gacttcgttt tctccacgac tttgttcatc tgacagcatc tttttatcat
    12541 aagcttttac aaatggataa tagataataa atgctatcaa tgtgttgatc atgatcaaga
    12601 taacaacacg ccagtcattt cctgctgaaa gataaccgcc gattggagct ggtaatgtcc
    12661 atgttggcaa aacagtaaat ctattgacca tttctaattt gactgcaaaa taactgataa
    12721 tagtcaaaac taaaggaact aagttgaacg ggatgaacat gtaaggattc aacatcatag
    12781 gagctccaaa aattatgggc tcattgatat tgaagatacc aggaataata gaaaaacgac
    12841 caacctcttt caagaatttt gatttacaga agaatataaa caaaacagat accacgatcg
    12901 ttgctcctgc accaccaatt gttaccgtcc attgataaaa ctgttcagga gcgatatagg
    12961 gtaattgggt ggcagctgta ccatctgcca atgcctttgc attctcatcc aacatgatca
    13021 gccacattgg acgaacaaca gcccctacaa tactcatgcc atggatacca aatgaccaca
    13081 acaaatggat caaaaacatt ggtagtaaaa caccaagcaa attattccct aaaatattgg
    13141 ttaaaggctc gaataacgat aataaggcag cgtttacatc aaagcccgcg acgcttcgaa
    13201 tcagccaagt aattgttaaa atgactgcac ctggaatcaa tgcctcaaaa ctacgggcaa
    13261 cagcaggtgg cacttgttct ggcattttga tagtaatatt tcgattttta aagaaacgat
    13321 atacttccac tgcaaaaatc atagataaga tccccgcaaa catcccagat gctcccaaag
    13381 aactcatagg taagacccag ccaagaggtg cctcttcagg agttaaaacg tttacaggaa
    13441 cttgtaacat aaagaacgtt cctaaagata atataccacc tgtcacacta tctaatccat
    13501 atgatttagc tagatccgaa cccataacaa aagttgcata aatagccatc aatcccatcg
    13561 tcatcctaaa gggtaaaaca atcgttgccg aataaggggc aataaattca ttccatccag
    13621 gaaacggtaa attgataaag accataaaaa atgtcccaat caaaatcaat gacaatgttg
    13681 aaacaacccc attacgaatt gctaataaat gacgctgtgt accaattttt gccattggtg
    13741 ggacaagttt ctcttcgacc catttcatca gcttttccac taaaaccact ccttttcaat
    13801 aaaatatgaa ccattcattg catgacaacg caaagaatgt tcataactaa ttatataatt
    13861 aagaaatttt atttcaatat attctcttaa ataatcaaat ttatttttaa gaatcctgaa
    13921 aataagtttt ctaaatcata ggagcaacaa aaaaattcga taattaacaa aaatcaaaat
    13981 gattaaatct agtgattgaa acatatcatt tcaaaaaaat tttgtaaatt cacccataaa
    14041 tatcacccta tttaactttt ttcatcgtac actaaaattc aaaacaacta tctttaatct
    14101 ttacttcttg gttttgtttt aataaatttc cttcaaaaat gcctggagaa actacaatga
    14161 tcaccgtatc tttttgtgct tgctccaact tcttcaaatc tataatagct aacagtgtcc
    14221 cttcttttac ctcctggtta ctttcaaccc gtatctgaaa cggacttcct tcgagttcaa
    14281 ctgtatctaa acccatatgg atcagtattt ttctgccaga ttcactttcg atcgttatgg
    14341 catgtcgggt aggaaatata ttatcgatta ttcctttaac tggcgcatgg atatatccat
    14401 catgattcgt tatagcgtat ccaactccta tcatttttga agaaaagacc tcgtctttta
    14461 ctgctgttaa tggaataatt tgaccactag ctacagcttt tagaatgttt cttgttttaa
    14521 agaaatgcac tttttatcac ctctacttta atgctggcca atattttttg tttactttga
    14581 tcatttcatc tagtattttt tttgcgactc tggcatttgg tacggtttga ttcaatgtaa
    14641 atgcttgtaa agctttttga taagaacctt caaagtaagc atctactagt aacttctcta
    14701 ctgcaacttg tgcctccatc aatcctttat gaaaatcact gattggtttt cttagtgtaa
    14761 ttggctccac accagttgca ccaacatatg ccggtatttc aacaactgca tctgaccgta
    14821 gattcggaat cgccccttga ttaggaacga ttagcataaa gcgacgacga tcatcattca
    14881 acaaggaaat agctatatcg acgatatatt gtccatgctc cccaaaatta aagttcaata
    14941 cttcttccac aataccgcgg cgtattttat cagccatttc tttggtattt ttctctcgtc
    15001 catccatgac catattagca cgtgtatact ctttgtcagt atgctcaacg accatatcag
    15061 gatataagta atactctaag taattattcg ggatattact tggaaaattt ttcgtgatga
    15121 ctgacatcat ttgaaaggtt ttttgccaag ttttatctcc tatattaaaa tcggcgactt
    15181 gcatttcttt tgttattagt ttttcaataa tctctggcat aatttctcgt tgcaattctt
    15241 tatcataaat cgatgtatac cagccaaagt ggtttaaacc ataatacgta acgatccaat
    15301 tcttacgatc ataaccgtaa ttcactgcaa tcgtttcttc aattgaaata gtcatatcac
    15361 aggcattaat catttttaca ttcggatatt tacgacgaac agcttcagaa acgatcgact
    15421 ctggatttgt ataattcaaa atccatgctt tgggggcata gtcttgtata tgatcgacaa
    15481 tttccaataa acctttgatt gagcgcatcc cataagcaaa tcctccgagt ccacacgttt
    15541 cttgtcctac taatccatgt ttaagtggaa tcttttcgtc cttttctcgc atctccaatc
    15601 ctccaacacg aatttgtgag aaaacaaaat cgcgtcctgt aaaagcaagc tttggatcat
    15661 ccgttgcacg aatgcgaata tttgaaaaac cttttctttt cagcataaat ttaacaatca
    15721 agtacatatc catatttctt tcttcatcaa tatcatataa acgtatttca gataatggca
    15781 accgtttttc attgttcaaa atggcttgaa cgattcctgg tgtatacgta ctcccgcctc
    15841 cagctatagt gataatctgt tttttcatca tcatcttttc ctttctattc ttctaataat
    15901 ttattgaatt ctgccataac ataagtcact tctaagccga tgataatttg ataatttttt
    15961 tcagttggtt taatgatccc gcttatccct aattgcttga ttcgctgttc ctcgaccatg
    16021 gtgggatcca ctacctctac ccgtaggcgt gtattacaac tatagacatc caggatattg
    16081 gcttttcctc caaacgcttg tagcattttt gttgccatat attcataatt tttacttgct
    16141 aaccctaact ctgtttcttc taaggttact tcattgccaa actctgcctt agcttcacgt
    16201 cctaatgtct gaatgtttct cttattgatc aaataataaa aagtaacgta atacaaggca
    16261 aaaaagaaaa ttccgattgg aagaatcaaa atagcattgg tagcgattcg aaaattgatg
    16321 agataatcaa caatacatgc tccgaatgta aaaccaattc gtatattgaa taagtaacag
    16381 acaatccctg ctaaaccggc aaaaagtgca tggatcacgt acaacatagg agaaagaaac
    16441 atgaaactaa attcaacagg ctcagtgata tttgcaataa atgaagttcc tgcaccgctt
    16501 cccatgattc ctttgaccat ctctttattt tctttataag ctgctttata gatagctaga
    16561 catatagctg gtataccaaa catcattact acaaaaaaaa ctgataaaaa cagtccagcc
    16621 tgaggatctc cgttgataaa gcgtgtcatc tctcctctga aaacttcctt gctaggagat
    16681 gtatagcttc ctaaatcgta ataaatatac gtattcaaca catggtgcag tccaaagggg
    16741 atcagcaaac gattcaaaaa cataaatatc cccacaccta atgctcccat atcaacgagc
    16801 agttttgcaa aattatcaat cccaatttgg atgagcggcc agataaagcc caaaaaaaca
    16861 gctgcgattg tttgtagaat catcaccata gtcaatggga atttttcgcc cgcaaaataa
    16921 gaaaaaacta ctggtaattt ttgttcttta aagcgattat acgtccatgc cgctactaaa
    16981 ccggaaataa ttccaccaaa aatccccata ttcacttctg ggtccataat ttctaagcct
    17041 tttttcaagg tagcaatcgc taaaaaacca gtaagtgcag gtattccttt gtccttattt
    17101 ttgacaaaac cgattgcaac tcctatagca aataagatat ccaagtttcc aaaaacggca
    17161 tttccagctg caccaattac tgggatgttc agcatatcgt cagctgataa acgcatgatc
    17221 aatcccgcta atggcatcgc tgcaactgga agtagcatcg ctcttccaag cttctgcaca
    17281 tttgatttaa cattcatttt tattcctcct ctattaaata tcctcatatg ttactaactc
    17341 aatcaaagga tcatttttca ctttttgagc aaatgctgaa tgaattaaaa attcgacttg
    17401 gtgggtacga ggatacacaa aacttgaacc atttaacaat tcctgatcca aatacgctgc
    17461 gtgacacatg acttcgatcg ttttatcttc tctcaatatc atgagtaaac ttgccaaata
    17521 ttcttccaca ctcgtattga tttgtcgttt tttttcatca gtttctccta cgacatcgaa
    17581 acaaggctca aaataatcga catgacgaac ttcatctttt cgttcaaagt tgctccgaac
    17641 cggcaaatca tatttttttg ctaatgtaac aactacctcc tgattttcat ccaaagtatg
    17701 agtatgatga tgactgtcta aatgagttgg tatgatcccc gcatgataaa ttttttgaat
    17761 ctgagcattc cattcctgat acagttgatc tttgtcaatg ttaaatggat gctgataata
    17821 agataaggat ctgaactctc cgctttcgat aagagtatcg acagttttga ggagtggttt
    17881 gccacacgtc aatgttaaat ggactcctac acctagccta ggcatttcct ttcttagttt
    17941 cacagcatgc tcgaaacccg gcatatttgc catcaatgta gttgatgtca aaattcctcg
    18001 ctgataagca tccataatcc cataattcac accatggcta tagccaaaat catccgaatt
    18061 aaaaatcact tttcccattt cattctcctt cttttttcta ctaaaatagg cgcaaccaaa
    18121 taatcatagt ccatttacta tgtgtcattt ggttgcgcct atagatagtt acgcccttat
    18181 tttaatagat tcttgctaga tgaattgcca aatagatgat ttcattttct tgaatggcaa
    18241 gttgaaattg ctgttcgatg atatctttaa tctttagtgc tgtacaatac gctttgctat
    18301 gtttaaatgt ttcagtaaaa aaaccaatat tttctactgg cgtttcttcc tgataaatca
    18361 agcgtttaac caggaatttg atatgaacca ttaagcgatg ataagtcagt gattctttat
    18421 cataaacgtt tgaataggat ttttctagat gggacaaaat cgtggtcgtc atttctacta
    18481 tttttaagct ctttaaacta ttaggctctc ctagctcagc attaatgata tgcatagtga
    18541 tgaatcctac ttcatttgac cctaactcgg tttgatatcg atgattgatt cgctcgacca
    18601 cttctactgc tatatcatat tcatttggat aaaggaatct catttctggc aacataattg
    18661 ctgtgacatc tctatcttct ctttttcgtt gaatagcaaa ataaatatga tctgtcaatg
    18721 taatatagat atttgaatct aatggagagg agatcctagc tgttatcagt tcaatcactt
    18781 cttccgcaaa atccataaat tcgattggaa tctgcgagac tatctcactg aatcgtttga
    18841 tcttttcttt agaatctaat acaaataatt tgtcagcatc ctcaacatca aatggcttac
    18901 tcactttagc agaaaagcca atccctttcc ccatcgcaat tttttctatt ccatcgtcat
    18961 cgatcaatac agcattatga ttcagctttt tcatcacata caccgttaat tcacctcctc
    19021 tatatgataa aacaaaacaa cttgcagact ccttcataca tatttttgtc tccaaacaat
    19081 ttttaaagac aaaaaacgac ctaagaaaga accctttctt aggtcgtgcc taattgaata
    19141 gtagcaccct acataattta caaaaatagt ttaacacata ataaaagcgt tatcaatatc
    19201 ttttttactc gttttatgat aatacttgta tcgaattgat ttggaggtaa ttacataaaa
    19261 acaaaaaaaa tatagcaact ctctataaga aagttgctat attgataatt ataccggcgg
    19321 ccggggtcga accggcacgt cctcaacgga cactggattt tgagtccagc gcgtctgcca
    19381 attccgccac gccggcaaat ttaaaaataa taactggggt agctggattc gaaccaacgc
    19441 atgagggagt caaagtccct tgccttaccg cttggctata ccccaagaat aaagggcgaa
    19501 tgatgggaat cgaacccacg aatgccggag ccacaatccg gtgcgttaac cacttcgcca
    19561 cattcgccat cataaaagat gttatttaat ttctcaataa aaaactaaga tgaagacatc
    19621 ttagtcaata ccggcggccg gggtcgaacc ggcacgccct caacgggcac tggattttga
    19681 gtccagcgcg tctgccaatt ccgccacgcc ggcaagttga tttattagta ctaaggcggt
    19741 aaccggattt gaaccggtga tgaaggtttt gcagacctct gccttaccac ttggctatac
    19801 cgccattata ctattatcaa tctataaaat aaagaataaa ttatagaaac tggggtagct
    19861 ggattcgaac caacgcatga gggagtcaaa gtcccttgcc ttaccgcttg gctatacccc
    19921 aagaataaaa agggcgaatg atgggaatcg aacccacgaa tgccggagcc acaatccggt
    19981 gcgttaacca cttcgccaca ttcgccatgg caggggcagc aggaattgaa cccacactaa
    20041 cggttttgga gaccgctgtt ctacctttaa actatgcccc tataaaatgg aggagagtgg
    20101 attcgaacca ctgaacccta aggaacggat ttacagtccg tcgcgtttag ccacttcgct
    20161 actcctccat ggtggcgcgg gacagaatcg aactgccgac acacggagct tcaatccgtt
    20221 gctctaccaa ctgagctacc gcgccatatt ttaaaattat taattgaata acaagaacga
    20281 cggttccgac gggaatcgaa cccgcgatct cctgcgtgac aggcaggcat gttaacccct
    20341 acaccacgga accagttcat tatggaggtt aacgggatcg aaccgctgac cctctgcttg
    20401 taaggcagat gctctcccag ctgagctaaa cctccaacat tcaattaaaa tgacccgtac
    20461 gggattcgaa cccgtgttac cgccgtgaaa gggcggtgtc ttaaccgctt gaccaacggg
    20521 ccaggtaaat ttgctacgga gagtaaggga ttcgaaccct tgagacagtt tggcaccatc
    20581 tacatgattt ccaatcatgc tccttcggcc tctcggacaa ctctccagag tgaaagaagc
    20641 tcaatactct ttctcaaaat gag
//
LOCUS       DACBZK010000047        20372 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.049, whole genome shotgun sequence.
ACCESSION   DACBZK010000047 DACBZK010000000
VERSION     DACBZK010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.049"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..189
                     /locus_tag="IVD66_001827"
     CDS             <1..189
                     /locus_tag="IVD66_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP6146032.1"
                     /translation="NSNGILRRNGLPKSIDFREVNQTFISSVSNQRNHIPRKSLNYRT
                     PIEIFLSYVQEAFYSSLI"
     gene            complement(1055..1585)
                     /locus_tag="IVD66_001828"
     CDS             complement(1055..1585)
                     /locus_tag="IVD66_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HAP6146033.1"
                     /translation="MRLGLIIKNILNLPKTIYFNYKFLHISDAWRLPILVHRKVRITR
                     KSRGKIEIVLQSGKIVYLGFPVLNTAGNEETIISIEGILRIQGPAFIAQGAHIDIRKN
                     AVLDIGSKFNSTGKMSIICFKEIQFKDGCTVSWDTLFMDTDSHTIFELNTHRILNKNN
                     KIVIGKHCWIGAKSVI"
     gene            complement(1582..2199)
                     /locus_tag="IVD66_001829"
     CDS             complement(1582..2199)
                     /locus_tag="IVD66_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAP6146034.1"
                     /translation="MIIVIAEIITDILYKLYEPFGFAVLLTILGLVYFMYATDGIAAG
                     EGYKRILMELYLHLKKDRKYRKVCALIFYTAMILFTTLINRTIWLNPLSDVMGDWWIY
                     KYNTTTGTKELSTACLENIILFIPYVYMVMSIKYENIKKPKIWSSIVYGGKIAFYFSA
                     IIEFLQLFLRLGTFQISDFVYNTLGGILGVILYKLILITKRDGER"
     gene            complement(2805..3002)
                     /locus_tag="IVD66_001830"
     CDS             complement(2805..3002)
                     /locus_tag="IVD66_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HAP6146035.1"
                     /translation="MGSSERIKIGNNVFIGMKSRILKGVHIGNNVVIGANSLVNKDVS
                     DDCVVAGNLAKVIMSLDEYYK"
     gene            complement(3180..4712)
                     /locus_tag="IVD66_001831"
     CDS             complement(3180..4712)
                     /locus_tag="IVD66_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP6146036.1"
                     /translation="MIINRKQNAKRNIITGTIFKLYQIIIPFFMRTLMIYQMGMEYAG
                     LNNLFTSIFQMLNLAELGIGAALTVSMYKPIAEDNRKEICALLNAYKKYFSIIGWIVF
                     TLGLLCIPFLRFLVKGSIPGNLNMTVLYLMYLINTVLSYWLFSYRKSLIYAHQRNDVI
                     NVSMLITFTFQFVMQAYVLIFLKNYYLYLLASILGQIVLNLMCAVVSQKMYPDYTPVG
                     ELEKETIDDIIKKVKGLVTNKVGGTILRSSDSIIISSFLGLSVLAIYQNYYFIISAIM
                     SIFAIIYESCIAGIGNSLIVESQEKNYIDFCDITTIIGWFLAISCACFITLFQPFMII
                     WVGSDNLMSISFVIFMIVHFFLYEIDQLIGLYKDAAGIWYADRFRPLITAMINIVLNI
                     ILVNWFGLYGVLAATIVSVLLVDLPWLLYNVFQNIFKFESAGKYVWKLISLCVIAFVA
                     SYLSYFACSYVNIGNFKVISLVINLVISVVISILVILLFNIRNKKFKYILKVLTSVLV
                     KR"
     gene            complement(4848..5933)
                     /locus_tag="IVD66_001832"
     CDS             complement(4848..5933)
                     /locus_tag="IVD66_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP6146037.1"
                     /translation="MKKICFISGVISRSGGTERVGSIIANSLSDLGYDVTILSFWNSG
                     EPYFGLDKTIKVDYMLNPKTEGKLYRTYLYPVWKLHKYICKNEFDIVIDIDTLLSLYT
                     TRAIKGTKCKLISWEHFNYWTMEMLKEKKRFKAKKLIKKYAKRLVVLTEEDRQKHIDE
                     YSLSEDFVITMPNPCISNIEYEYHYDKKRFLAVGRLVEEKNFADMISAWKIVEKKVDD
                     WDLIIVGKGELEKDLRQQIKDLNLQRVTIAGHSDHVEEYYKSASCYVLSSVYEGFPMV
                     ILEAQSYGLPVISYDCKTGPRDLVHHNFNGMLVEDKNIDQLAKSMIMFTKNTDLAMRM
                     SLNAYNNVQKFNLKEITKQWVALIENV"
     gene            complement(5948..6667)
                     /locus_tag="IVD66_001833"
     CDS             complement(5948..6667)
                     /locus_tag="IVD66_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAP6146038.1"
                     /translation="MIPKKIHYCWFGGNPLPKKDRKCIESWKKYCPDYEIIEWNESNY
                     DLNKNRYMADAYKERKWGFVPDYARFDIIYNHGGFYLDTDVELIKSLDILRENHAYMG
                     FEGEIWVNGGIGFGAEEGHSVIKGLRDIYDSLSFYQNDGTLNLKPSPYYITDYLESIG
                     LVRDNSEQIINGLHIYPTDYFAAKDYDTGKIYKTSNTISIHQYNASWKTPKQKFVYRL
                     KSTIGQKKFNRLLALKKFLHL"
     gene            complement(6664..7974)
                     /locus_tag="IVD66_001834"
     CDS             complement(6664..7974)
                     /locus_tag="IVD66_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAP6146039.1"
                     /translation="MRISIKRWSGADWTLFTLAFFAISIVLVYTFNAPRAILYLGDII
                     NIFVLLNALSFRRRKGIYASKNEMLIVLFLLVSICSSVINLENIGLIIWGIRNNTRMF
                     IVYINCATYLTIKDYYKVFAIIEKLFWISLPLCLIERFMVTYPTGTIVGDMIGGVFWN
                     YSGCNMPLNLILCVTVTVVTIGYFKGEKNFIHFILCVCAALFMSALAELKVFIPELFI
                     IFVAIVFTLKVDFKVVIKILSCVILVSIVLSFFITIFITLNDNGQSYADNFTIQGLLE
                     YASRDSGYDGVGDLNRITGISRVVDEIFNNNFRLVLMGVGIGNAEFTNFFVSEFYKSF
                     GNLHYQYFHHIWLFIEVGILGVSIFLFFIIKTFFNAKRSFMKDKDASLVKVIAIMSVF
                     FFVYNTTLRGETTGPLIYMILAMPEVVKRKEHYYSEKNTKGEIL"
     gene            complement(8001..8591)
                     /locus_tag="IVD66_001835"
     CDS             complement(8001..8591)
                     /locus_tag="IVD66_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HAP6146040.1"
                     /translation="MEISSKEYLKAVLRMEKNLYIESKGQHTKLLKIMKSHPDYNAWR
                     YTRRMRITSYYYSKRKKNIIYAIMYIVSCRRMNSLGRKCGIECGENVFDEGVRFYHTQ
                     GIVINGNAIIGKNCYLYGNNCIGNDGIDPKCPVIGNNVRVCVGAKIIGNVKIANNVVV
                     AAGAIVIKDCLENGAILAGVPAKIIGYVNLTKVFLE"
     gene            complement(8909..9970)
                     /locus_tag="IVD66_001836"
     CDS             complement(8909..9970)
                     /locus_tag="IVD66_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP6146041.1"
                     /translation="MNSSDLISVIIPVYNVEKYVGSCLESVCNQTYKNLDIIIVDDGS
                     KDSSNKICEDYALKDSRIRIIHKNNAGLGLARNTGLEHVKGKYVAFIDSDDFVAANYI
                     EAMLNGIKRSNADTCYAGYYEYYDDNNIISKPARYDSTIFTNNAIIEKVLLGMIGTEP
                     SYKVDFILPMSVWHALYSSEIIQQHNIKFPSERDYISEDIIFHISYLQHSKITSFIKD
                     CIYYYRCNNNNSLTHNFRDNEFDCNIELVKKIEGDLSYILENEIFVNKTRRLLLGRCR
                     TCIQKAVRYASFNKEFDLNSYLSKILMNDELIACIHSYPYKQNPIKQRIFNYFLLNQS
                     IIGVKTLAYLSGMGRNRRF"
     gene            complement(10538..11605)
                     /locus_tag="IVD66_001837"
     CDS             complement(10538..11605)
                     /locus_tag="IVD66_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP6146042.1"
                     /translation="MQRVLMIGNDSSVKGGITSIITQMLNFNWEKKNIEMTFIPSYKG
                     GNAIFKSLYFMYAFAKIIGISLLSKPNIIHMHMSYRGSFSRKYVLNKWFRLLNIPVII
                     HLHGSEFKKWYDSVSVKKQNQIRLLLRESDSTIVLGEKWKKIIKEIEPNCKTVVVENS
                     IVVPEYTIKWNSKMCRFLFMGVLIKRKGVHDLVEAVKNIAEQYPEKKFIFEIAGAGDE
                     EISLKELIEEYNLQSYFEFTGWVVGEKKEECYRRSNVMILPSYNEGLPISILEAISYG
                     MPVIATDVGDISSAVRDGENGYLFQPGDVSALTSAILKINDKDKYVKFSRCSKDLAIT
                     KFNDGNFFDRILNLYQKGSKE"
     gene            complement(11625..12104)
                     /locus_tag="IVD66_001838"
     CDS             complement(11625..12104)
                     /locus_tag="IVD66_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta(1,3)galactosyltransferase EpsH"
                     /protein_id="HAP6146043.1"
                     /translation="MIFITLGSQKFQFDRLLKAIDDLIEKGVIIESTFAQSGYSDYKP
                     LNYSYKAFLNRDEFTETMQKAEMVITHGGTGAIIGAVKKGKRVIAVPRLAKYGEHVDD
                     HQLQLIRQFDEMNIIYPCYELENLEDAVKETRVRMFNKYVSNTETIINSIEVLIEKI"
     gene            complement(12121..12582)
                     /locus_tag="IVD66_001839"
     CDS             complement(12121..12582)
                     /locus_tag="IVD66_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP6146044.1"
                     /translation="MNKKICFAASSGGHYEQLMMLKPLMEKYESFVITEQTEYSAESK
                     GEKTYYMRQVNRKEKFFLCTILINLFKSIIIYIKEKPDLVICTGVLAMIPICLITKMM
                     GKKLIYIESFAKVTSPTQTGKLMYHFADQFYVQWETMLQFYPNAIYLGGIY"
     gene            complement(12596..13846)
                     /locus_tag="IVD66_001840"
     CDS             complement(12596..13846)
                     /locus_tag="IVD66_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HAP6146045.1"
                     /translation="MKKKYNIAVAGTGYVGLSIATLLAQHHQVTAVDIIPEKIELINK
                     RKSPIQDEYIEKYLTEKELDLTATLDARSAYKSADFVVIATPTNYDSRTQHFDTSAVE
                     SVIEVVMDVNPDTIMVIKSTIPVGYTESVRETTGSKNIIFSPEFLRESKALYDNLYPS
                     RIIVGTDMTDERLLNAAHVFATLLQKSAIKENVDTLFMGFTEAEAVKLFANTYLALRV
                     SYFNELDTYAEMKGLNTQQIINGVCLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYA
                     DVPGNLIEAIVESNRTRKDFIADRVLQMAGYYNYAEYNQYDVNRENPVLIGIYRLTMK
                     SNSDNFRQSSIQGVMKRVKAKGATVVIYEPALKDGETFFGSKVINDLEQFKAMCDSII
                     ANRYDTCLDDIKEKVYTRDIFQRD"
     gene            complement(14224..15675)
                     /locus_tag="IVD66_001841"
     CDS             complement(14224..15675)
                     /locus_tag="IVD66_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAP6146046.1"
                     /translation="MYKKSSRGWVKHIDFIILDLLCIQLAFYLSYVLRQVDWNPYVIP
                     MYQNMAVFIELADLLVIFMFEAYRGVLKRGYYIEFASSVKQAIMLVLLGSLYLISVQG
                     GNDYSRVVLFLMGGLYVVITYITRLLWKHYLKHKMKNEGNKSLIIVTSSSIAEVVIRN
                     VKEHNYKMYKINGVIIIDKSMIGEDVEGVTVVSDSKNAADYLCQGWVDEVFIILNKST
                     SCMKEFIERCSEMGLTVHLNLAKVSDSALGKQSIGRIGEYTVLTTSINVMTTQQAFIK
                     RTIDILAGIVGCIATGIIFIFIAPLIYINSPGPIFFAQERIGQNGKPFKMYKFRSMYM
                     DAEERKVELMKENKMSNNLMFKMEFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FFNVLTGKMSLIGFRPCLKSEYEEYDYHHRARIAIKPGITGMWQVSGRSDITDFEEVA
                     KLDTEYIKNWSMGLDFKILFKTVKTVLQRGGSM"
     gene            complement(15996..16760)
                     /locus_tag="IVD66_001842"
     CDS             complement(15996..16760)
                     /locus_tag="IVD66_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HAP6146047.1"
                     /translation="MIDLHCHILPGIDDGAESLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNVHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(16788..17486)
                     /locus_tag="IVD66_001843"
     CDS             complement(16788..17486)
                     /locus_tag="IVD66_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HAP6146048.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAS
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILSEARQLFDV
                     VIFDMPPVVAVTDAQIMSLKTDGTLLVVRENMSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(17498..18277)
                     /locus_tag="IVD66_001844"
     CDS             complement(17498..18277)
                     /locus_tag="IVD66_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HAP6146049.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAQTQPKATNDKTAPSRRSRSRV"
     gene            complement(18293..19237)
                     /locus_tag="IVD66_001845"
     CDS             complement(18293..19237)
                     /locus_tag="IVD66_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP6146050.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(19283..20062)
                     /locus_tag="IVD66_001846"
     CDS             complement(19283..20062)
                     /locus_tag="IVD66_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146051.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADIQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIEQIRNEKISAAYATKAQTVAEQMGYSNISY"
BASE COUNT         6483 a         4051 c         2621 g         7217 t
ORIGIN      
        1 aattctaacg ggattctgcg tcgtaatgga ctgccgaaat caatagattt tagagaagtg
       61 aatcagacat ttatttccag tgtcagcaat caacgtaatc atattccaag aaaatcattg
      121 aattacagaa caccaatcga aatatttttg agctatgtac aagaagcatt ttattctagc
      181 ttaatttgac aaatcatata atttaaaatt aacattgatt ctcctatgaa aatatctttt
      241 acctttctcc tgtgaaaagg aaatttcctt ttttatagtg ttattgatat aatcagaata
      301 ttcatcaaac tctgtatctg gagttaaaaa tctacagtaa catctataag ctttgctagt
      361 aatcttcttg ggttctctct ccattgtcaa gcaacatcaa aacacctact tactattcga
      421 ttcttttctg ccaaaaacga gtcagcatca ctcacaactt atgtgttgct gactccgact
      481 agtcctttgt tcaatatcaa cttattaaac agatataata tttttcttta tttcgtatac
      541 tccaagactt ccatctttct ttcatcttat ctctgaaaaa aacacagcaa agtgccctta
      601 ataaatatac attagaattt gcaaattttt tcatcttaag atatatccta ttcatattct
      661 ttacaatcct aatgggtgat tacaaatcta tttagttcaa gttctacatt ataaacacct
      721 ttcttgatag tatcatctgc tgcacaagcg atgtcgatcc acttattagg ggatttacgt
      781 gctcaaaagt ggctattcct tttgggaagt ccatccataa taatggtcca tggatttttt
      841 tagggtcttg tcgttcaaat ttctcaaaaa ctttattata cttccatagt tttataatta
      901 tttggtttca ctttggctcg ttcaaacacc aacttgtatt tcttttcaac gttcgaactg
      961 gagccccccc tataatctca ttattatttt catgactttt tactaccgtg gaattacaag
     1021 caacaacaat attatctgct aaatgaacac ctttctatat cacgcttttt gctccaatcc
     1081 aacaatgttt acctataact attttattat ttttattcaa aatcctatga gtattcaatt
     1141 caaaaatcgt atgtgaatcg gtatccataa ataatgtatc ccacgatact gtacagccat
     1201 ctttgaattg aatttcctta aagcaaatta tactcatttt tcctgtcgaa ttaaactttg
     1261 acccaatatc taaaactgca tttttcctta tgtcaatatg agccccttgt gcgataaacg
     1321 ctggcccttg tattcttagt attccttcaa tacttataat cgtttcttca tttcccgcag
     1381 tatttaatac tggaaagccc aaataaacta tttttccaga ttgtaatact atctcaattt
     1441 tccctctcga tttgcgtgta atccgtactt tacgatgcac caaaataggt aatctccacg
     1501 catctgaaat atgaagaaat ttataattga agtatatcgt tttaggtaaa tttaatatat
     1561 tctttattat caatccgagt ctcatctttc accatctctt tttgtaatca aaattagttt
     1621 ataaaggatt acacccaata taccgcccaa cgtattatat acaaaatccg aaatttgaaa
     1681 cgttcctagc ctcaaaaaaa gttgtaaaaa ttcaattatt gctgaaaaat aaaatgcaat
     1741 ttttcctcca tatactattg aggaccatat tttgggtttc tttatatttt catatttaat
     1801 agacattacc atataaacat atggaataaa aagaataata ttttctaaac acgctgtaga
     1861 taactctttt gttccagttg ttgtattata cttataaatc caccagtctc ccataacatc
     1921 agataaagga tttaaccaaa ttgttcgatt gattaatgtt gtaaataaaa tcatcgcagt
     1981 atagaatatc aaagcacaaa cttttctata ttttctatcc ttctttaaat gaagataaag
     2041 ttccattagt atacgtttat agccctcacc tgcagcaatg ccatctgttg catacataaa
     2101 atagaccagt cctaaaattg tcaataaaac agcaaaccca aagggttcat ataatttata
     2161 taatatatct gtaataattt ctgcaatcac tattatcata attatttctc caatatcaag
     2221 tatacactta tcgcttccaa ttacacatga tcatattaga gtgtattatc acattctcta
     2281 atattcaatt tatttttcct aaaatattcg aaataatcgt cttgataacg agtaagtatt
     2341 tttatacgat tgataacata gtaacaatat ttttaattat agtaaaaaat catctgcctt
     2401 tttcatccac ctaatcttat ttttcatttt attcaacatc cttaaataaa cttccgttcc
     2461 taagctctat aatatcttct taaaaaataa tattatggtg tcgttttcaa actcgtaatc
     2521 ttttacattg gaaaaataca tacttttctc aatgtagcaa ctcctatctc acagtattca
     2581 aaaattcttc aatattatga aatacttgtg catgttcttt aaataccttg tcagtctgtt
     2641 tataatcccc tactaaattt tgcattgctc ccaactcttc gacaaattgt catctccatc
     2701 tgtaaacagc cctaaaaact catataatgc tttttcatca atatttttcc catattattc
     2761 tcggtatagt ttcacaagtt ttacggattc ttcatattgt ttatctattt ataatattca
     2821 tctagggaca taattacttt tgctagattt cctgcaacaa cacaatcgtc tgatacgtcc
     2881 ttgtttacta aactatttgc acctataact acattatttc ctatatgtac accctttagt
     2941 attctagact tcattcctat aaaaacatta ttacctattt tgatcctctc cgatgatccc
     3001 aaagcttctc catactactt ttaaaaccga tcaatcataa acatgagtca aaattgtaac
     3061 tccttcatat catctccaat ttcaacaaga gtcttcgttg gaacaaaaac tatacatcgt
     3121 tcgcctattc ggcagcctaa aaattgtagt tactttatat atcattctga tgtctcttct
     3181 catcttttta ccaataccga cgtaagaact ttcaaaatat acttaaactt cttattacgg
     3241 atattaaaca gaagaataac taaaatcgat atgacaaccg atataactaa atttatcact
     3301 aaacttatca ctttgaaatt tccgatatta acatacgaac aagcaaaata acttaaataa
     3361 gaagcaacaa aagctattac acacaaactt atgagcttcc aaacatattt acctgccgat
     3421 tcaaatttaa atatattttg gaaaacatta tataataacc agggtaaatc aaccaacaat
     3481 actgaaacaa tggttgccgc caaaactcca tataatccga accaattaac gaggatgata
     3541 tttaatacaa tgtttatcat tgctgtaatt aatggtctaa acctgtctgc gtaccatatt
     3601 ccagcagcat ctttgtataa cccaattaac tgatcaattt catataagaa aaaatgaact
     3661 atcataaata taacaaatga aatactcata agattatcac ttcccaccca gataatcatg
     3721 aacggctgaa ataatgtaat aaagcatgca caactaattg ccagaaacca acctataatt
     3781 gttgtaatat cacaaaaatc tatataattt ttttcttgac tttctacaat aagactgtta
     3841 cctatacctg ctatacatga ttcataaatt attgcaaata tactcattat ggcagaaata
     3901 ataaagtaat aattctgata aatcgcaagt actgaaagac ctaagaaaga tgaaataata
     3961 attgaatctg aagatcgtaa tattgtaccg cctaccttgt ttgtaactaa tccttttact
     4021 ttttttataa tatcgtcaat agtttctttc tctaactcac caacaggagt ataatcagga
     4081 tacatctttt gagaaacaac agcacacatt aagttaagaa ctatttgtcc caaaatagaa
     4141 gccaataaat acaaatagta attttttaag aaaatcagaa catatgcctg cattacaaat
     4201 tggaatgtaa aagtaattag catagacacg ttaattacat catttctttg atgtgcatat
     4261 attagactct ttctatatga aaataaccaa tacgacaaaa cagtatttat caaatacatt
     4321 aaatacaaaa ctgtcatatt taaatttcca ggaatcgaac ctttaactaa aaatctcaaa
     4381 aaaggaatgc ataacaatcc taatgtaaac actatccatc caataattga aaagtacttt
     4441 ttatatgcgt tcagtaaagc acaaatctct tttctattgt cttctgctat aggtttatac
     4501 atacttacag ttagtgcagc acctattccc aattccgcta aatttaacat ttgaaatata
     4561 gatgtgaaca ggttgttcaa tccagcatac tccattccca tctgataaat cataagtgta
     4621 cgcataaaaa agggaatgat aatctgatat aacttaaaaa ttgttccagt aattatattc
     4681 cttttagcat tttgtttacg attaattatc atatcatatg gctccaaact ttctattttt
     4741 tattgttacc taatactata taatttctaa aatcttgaaa tgtaataggt ttcttctagc
     4801 tctttgatta attacgctaa ttttcatgtt tggacaacca caaaaaacta tacattttca
     4861 atcaaagcaa cccattgttt tgtaatttct ttcaaattaa atttttgtac attattatat
     4921 gcgttcagtg acattctcat tgctaaatca gtattcttag taaacattat catgctctta
     4981 gctaattggt ctatattctt atcttcaacc aacatcccat taaaattatg atgtaccaaa
     5041 tctctcggac cagttttaca atcataagaa ataactggta atccataaga ctgtgcttct
     5101 aatataacca taggaaatcc ttcataaaca gaactaagca cataacaaga tgcagattta
     5161 taatattcct ccacatggtc tgaatgccct gctatagtta ctctttgcag atttaaatct
     5221 tttatctgct ggcgaagatc tttttctaat tcaccttttc ctacaatgat aagatcccaa
     5281 tcatctactt ttttttctac aattttccaa gcacttatca tgtcagcaaa atttttctct
     5341 tccactaatc gccctactgc aagaaatctc tttttatcat aatgatattc gtactcgata
     5401 ttagatatac acggatttgg catagttata acaaaatctt ctgataaact atattcatca
     5461 atatgttttt gacgatcttc ttctgtgaga accacaagcc tctttgcata tttttttatc
     5521 aattttttag ccttgaatct cttcttttct ttcagcattt ccattgtcca gtaattaaaa
     5581 tgttcccaag aaatcaattt gcactttgtt cctttaattg cccttgtagt atacaaagac
     5641 aacaaagtat caatatcaat tactatatca aattcatttt tgcatatata cttgtgcaat
     5701 ttccaaaccg gatataaata agttctatat aattttccct ccgttttagg atttaacata
     5761 taatcaacct taatcgtctt atctaaccca aaataaggct ctccactatt ccaaaagctt
     5821 aaaatagtga catcataacc taaatcagac aagctattgg caataatact ccctactctt
     5881 tcagttcccc cagaacgaga aattacacca ctaatgaaac aaattttctt caaagtactt
     5941 ttctccttta taagtgtaaa aattttttca gtgcaagtaa cctgttaaat tttttttgtc
     6001 caattgttga ttttaatcta taaacaaatt tttgtttagg tgttttccaa gatgcattat
     6061 attgatgaat gcttattgta ttactagttt tataaatttt tccagtatca taatccttgg
     6121 cagcaaaata atccgtagga tagatatgca ggccatttat tatttgttcg ctgttatcgc
     6181 gaaccaatcc aatagattca agataatctg taatataata cggactcggt ttcaagttca
     6241 atgtaccatc attttgataa aaacttaatg aatcgtaaat atcccttaaa cctttaataa
     6301 cagaatgtcc ttcttctgca ccaaaaccaa taccgccatt aacccagatt tccccttcaa
     6361 atcccatata ggcatgattt tcacgaagta tatctaacga cttaattagc tcaacatctg
     6421 tatctaaata aaatccacca tgattataaa taatatcaaa tcttgcataa tctggaacaa
     6481 aaccccattt acgttcttta tatgcatcgg ccatataacg gttcttattt aaatcataat
     6541 ttgattcatt ccattcaata atctcataat cagggcaata ctttttccag ctttctatgc
     6601 actttctatc ttttttcgga agtggatttc ccccgaacca acagtaatgt atcttcttag
     6661 gaatcataat atctctcctt ttgtattttt ttcactataa taatgctctt tccttttcac
     6721 aacttcaggc atggctaaaa tcatataaat cagtggcccc gttgtttcac ccctaagtgt
     6781 tgtgttatac acaaaaaaga ataccgacat aattgcaata actttaacaa gacttgcatc
     6841 tttatccttc ataaaagatc tttttgcatt gaaaaatgtc tttattataa aaaataggaa
     6901 tatcgaaact cctaatattc caacttctat aaataaccaa atatgatgaa aatactgata
     6961 atgaagatta ccaaacgatt tataaaactc actgacaaaa aaattggtaa actctgcatt
     7021 gccaatgcct actcccatta ggactaatct aaaattatta ttaaatattt catctactac
     7081 tctagagata ccagttattc gatttaaatc accaacacca tcatatccag aatctcttga
     7141 cgcatattct aaaagacctt gaattgtgaa attatcagca tagctttgtc cattatcgtt
     7201 caatgtaata aatattgtta taaaaaagga taatactatc gacacaagta ttacgcatga
     7261 taatatcttg atcactactt taaaatcaac ttttaaagtg aatactattg caacaaatat
     7321 tataaataat tcaggaataa aaactttcaa ttcagctaat gcagacataa aaagtgctgc
     7381 acaaacacat aaaataaaat ggatgaaatt tttttctccc ttgaaatatc cgattgtaac
     7441 aacagtaact gtcacacaca aaattaaatt caatggcata ttacaacctg aataattcca
     7501 aaaaactcca cctatcatat ctcctacaat tgttccagtt ggataggtga ccatgaatct
     7561 ttcaattaaa caaagtggca gtgaaatcca gaataatttt tcaattatag cgaatacttt
     7621 atagtaatct ttaattgtta aatatgttgc acaatttata tatactatga acatacgagt
     7681 gttatttcgt atcccccaga taatcaatcc tatattttct aaattaataa ctgagctaca
     7741 aatagaaact agtaaaaaca aaactatcag catctcattt ttgctagcat atattccttt
     7801 tctgcgtcta aagctaagtg catttaataa cacaaagata ttaattatat ctcccaaata
     7861 taaaattgct cttggggcgt taaaagtata tacaagaact atggagattg caaaaaatgc
     7921 caacgtgaac aatgtccaat ctgctcctga ccatcttttt attgaaatac gcatcgttat
     7981 tcaccttctt tcgctaaaaa ttattctaaa aatacttttg ttaaattaac ataccctatt
     8041 atttttgccg gtacacctgc aagaattgca ccattctcta gacaatcttt gataacaata
     8101 gctcctgccg caacaactac attgttagct atttttacat taccaataat ctttgcaccc
     8161 acgcatacac gtacattatt tccaattaca ggacacttag gatcgattcc atcatttcca
     8221 atacagttat tcccatataa gtaacaattt tttcctatta tggcgttacc attaataaca
     8281 attccttgtg tatggtaaaa tcttacacct tcatcaaata cattttcacc acactctata
     8341 ccacattttc ttcccaaact attcattctt ctgcaagaca caatatacat aatcgcataa
     8401 atgatatttt tctttctctt tgaataataa taagatgtaa ttctcattcg acgagtatac
     8461 cgccaagcgt tgtagtccgg atgtgatttc attattttta gtaattttgt gtgttgtcct
     8521 ttagattcta tatatagatt cttttccata cgaagaaccg cttttaaata ttctttactg
     8581 ctaatttcca ttcatatctc ctattaattc aatttatact taacaatttt attcggattt
     8641 cttgcaacaa gagcatcatt caatgctact gaatctacaa cgatggatat gttatcttca
     8701 tcgttgattc caccggatac aatattactt ataaaaatcg taacattttt tccaaaagaa
     8761 gggatgtccg tgatgtataa tgcccatttt ccgatatttc cagttattta aacctaacga
     8821 atttttacaa tagtacaagt atcacaatca ttaatatata actggaatat aaatctccaa
     8881 aaattcacta tagtacagtt ttttatgatt aaaatctcct atttctaccc attccgctta
     8941 aatatgctaa tgttttaacc ccaataatgg attggtttag taaaaaatag ttaaatattc
     9001 gttgtttaat tggattttgt ttatatgggt atgagtgaat acaggcaatc aactcatcgt
     9061 tcataagtat cttagacaaa taggagttta aatcaaattc tttattaaaa ctagcatatc
     9121 taactgcctt ttgaatacaa gtacgacagc gtcccaacaa aagtctcctt gttttgttta
     9181 caaatatctc attttctaat atatagctta aatcgccttc aattttttta actaattcaa
     9241 tattacaatc gaactcatta tctctaaaat tatgtgtcaa tgaattatta ttattacatc
     9301 tataataata gatacaatct ttaataaaac ttgttatttt tgaatgttgc aaatatgaaa
     9361 tatggaatat gatatcttca gatatataat ccctttctga cggaaacttg atattgtgct
     9421 gttgaattat ctcagatgaa tacagcgcat gccaaactga cattggcaat ataaaatcga
     9481 ctttataact cggctcagtg ccaatcattc caagcaacac tttttcaatt atagcgttat
     9541 ttgtaaatat cgtactatca tatcttgctg gctttgaaat aatattatta tcatcataat
     9601 attcataata tccagcataa catgtgtctg cattactcct ttttatacca tttaacattg
     9661 cttcaatata attagctgca acaaaatcat cagaatcaat aaaagcaaca tattttcctt
     9721 ttacatgttc aagtcctgta tttcttgcca atcccaagcc agcattattt ttatgaataa
     9781 tacgaatcct tgaatccttt aatgcatagt cttcacatat tttattagat gaatccttag
     9841 atccatcatc cacaattata atatctaggt tcttatatgt ttgattacac actgattcca
     9901 aacaacttcc tacatacttt tcaacattat atacaggtat gattacacta attagatcac
     9961 tcgaattcat ccttctatcc tttcactcac gttttctcaa ttagtcaatg acggcatcaa
    10021 cgattttctt aaattctctg aaaaaaatag actctgatct tgatgatgtg aatgacatac
    10081 tatcttcttc tagaaaaatt atttccttta aattatttat taaatcaata atatgatcct
    10141 cgtaagtatg ctttcccttg gaataatgaa aatatacttt tgtattacac aatattgcaa
    10201 ttttatttct taatatgatt atttcactca ttcattactg ccacatatac acaacttata
    10261 accaccccct gcaaagttta gggtaagtta tcagataata tcttcctctt catcatccag
    10321 aatacaaaat ctatttattt atagaaatat cattaatgtt tttatataat gtaccgtgct
    10381 tgtactcttg ctctattaca agcactaaaa cactactatt catttgaatt cttacacgga
    10441 taaaaattta catcgtctat ttcaatattt tttctctcta ttttattcac ttaataagtt
    10501 cattacataa tcgaaacatt ttttattttc cttgtcatca ctccttgctc cctttttgat
    10561 acagatttaa aattctatca aagaaatttc catcgttaaa tttcgttatt gccaaatcct
    10621 tcgaacaacg tgaaaatttt acgtatttat ctttatcatt gatttttagt attgcagatg
    10681 tcaacgctga tacgtcacca ggttgaaaca aatatccatt ttctccatca cgtactgctg
    10741 aagaaatatc tcctacatct gtagcaatta caggcattcc ataagaaatc gcctctagaa
    10801 tagatatagg caatccctcg ttataggacg gtaaaatcat cacatttgat cttctatagc
    10861 actcctcctt tttttctccc acaacccaac ctgtaaattc aaaatacgat tgcaaattat
    10921 attcttctat caattctttg agcgatattt cttcatcacc tgctccagca atctcaaaaa
    10981 taaacttttt ttctggatat tgttctgcaa tgtttttaac tgcttctacc aaatcgtgta
    11041 caccttttcg ctttatcaaa actcccataa acagaaatcg gcacattttt gaattccact
    11101 ttatggtata ttctggaact acaatagaat tttctacaac aacagtttta caatttggct
    11161 caatttcttt aattatcttc ttccattttt ctccaagtac aatcgtggaa tcagactctc
    11221 ttaacagcaa gcgaatctga ttttgttttt ttacagaaac actatcatac cattttttaa
    11281 attccgatcc atgaagatgg atgattacag gaatatttaa taatctaaac cacttattca
    11341 gcacatattt cctactaaaa ctccctctgt acgacatgtg catatgaata atattaggtt
    11401 tactcaataa agagatacct ataattttag caaatgcata cataaaatat aaagatttaa
    11461 atattgcatt tccaccctta taactcggta taaaagtcat ctcgatattc tttttttccc
    11521 aattaaaatt gagcatttgt gtaattatac ttgtaattcc accttttacc gagctgtcat
    11581 taccaatcat aagtactctt tgcataacgc tttactcctt atatttatat tttttctatt
    11641 aatacctcta tcgaattaat aatcgtttcc gtgttagata catacttgtt aaacatccga
    11701 actcttgttt ctttaacggc atcttctaaa ttttctaatt cataacaagg atagataata
    11761 ttcatctcat caaattgtct aattaactgc agttggtgat catcgacatg ctcaccatac
    11821 ttagccaatc gaggaacagc aatgaccctt ttaccttttt ttacggcccc aattatagca
    11881 cctgtacctc catgagtaat caccatttct gctttttgca tagtttcagt aaactcatcc
    11941 ctatttagaa atgctttata ggaataattt agtggtttat aatcactata accactctgt
    12001 gcaaatgtac tttcgattat tactcctttt tcaattaaat catcaatagc ttttaacaat
    12061 ctatcaaatt gaaatttttg tgaacctaat gttataaata tcattttttt ctcctattat
    12121 ttaatatatc ccacccaaat aaatagcatt aggataaaat tgtagcatag tttcccactg
    12181 aacataaaat tgatctgcaa aatgatacat caattttcct gtctgagtag ggctggttac
    12241 ttttgcaaac gattcaatat aaatcagttt ttttcccatc atttttgtta ttaagcagat
    12301 agggatcata gctaaaacac ctgtacaaat cacgagatcc ggtttttcct ttatatatat
    12361 aataattgat ttgaataaat taataagtat agtacacaaa aaaaactttt cttttctatt
    12421 tacttgtctc atgtagtacg ttttttcgcc ttttgactca gctgaatatt ctgtctgttc
    12481 tgttataaca aaactctcat acttctccat cagtggtttt aacatcatta actgttcata
    12541 atgcccccca gaggaagccg caaaacatat ctttttgttc atattaacct ctctatcagt
    12601 cacgctgaaa aatatctcta gtgtaaactt tttctttaat atcatccaag caggtatcat
    12661 atcgattggc aataatagaa tcacacatcg ccttaaactg ctctaaatcg ttgataacct
    12721 tacttccgaa aaaagtctct ccatctttca gtgcaggctc ataaatcacc acagtcgcac
    12781 ctttagcttt tacgcgcttc ataactccct ggattgaact ctgacgaaaa ttatcactgt
    12841 tgctcttcat ggtcagccgg tatataccga ttaaaactgg attttccctg ttgacatcat
    12901 actgattata ttcagcgtag ttgtaatagc ccgccatctg aagaacacga tctgcgatga
    12961 aatccttacg ggtacgatta gattcaacga tagcctcaat caaatttcca ggaacatctg
    13021 catagtttgc caacaactgc ttggtatctt ttggcaagca ataacctcca tatccaaagg
    13081 atggattgtt gtagtgagtt ccaatacgag gatcgagaca aacaccattg attatctgct
    13141 gagtattcag ccccttcatt tcagcataag tgtctaattc attgaaatag ctgactcgca
    13201 gtgctaaata ggtatttgca aacagcttta ctgcttcggc ttcagtgaat cccataaaaa
    13261 gagtatccac gttctcctta attgcacttt tctgcagaag tgttgcaaaa acatgagcag
    13321 catttaacaa gcgctcatca gtcatatcag taccaacaat aatacgagat ggatacagat
    13381 tatcatataa agccttgctc tcgcgcagaa actctggact aaaaataatg ttcttactcc
    13441 ccgttgtctc acggactgat tcagtgtagc caacaggaat tgtagacttg atgaccatga
    13501 tggtatcagg attcacgtcc atcacaacct caataactga ctcaacagca gaagtatcga
    13561 aatgctgagt acgactgtca tagttagtcg gtgtagcaat aacaacgaaa tctgcggatt
    13621 tataagcgct ccttgcatcc aaagtagcag ttaagtcaag ttctttttct gtaagatact
    13681 tttcaatata ttcatcctga attggagact tccgtttatt aatcagttca atcttttcag
    13741 ggataatgtc taccgcggtt acctggtgat gctgcgccaa tagtgtggcg atactcaaac
    13801 caacataacc ggtgccggct actgcgatgt tgtacttttt cttcacaata tctcctcttt
    13861 cctctcttaa gtatggagaa tgttactcct acggctattc atcatgtcaa aataacacag
    13921 cttagaatgt tgataaaata attttccaga atgtgataaa atctctttca tttataaacc
    13981 acacatctaa ttttatctat tctccacaag acatgtagag tattctttaa taacaagata
    14041 cgaccttact aaatacttca aaaaattatc atatttaatt cataaatata aatcttcatt
    14101 ttaaatgtat gcccaaaaat ttatctgtaa tgcgtcatca aaatctagat tccaaatctt
    14161 tatcaatttt tatccactca ttctaccact ttagtaatat tttctattta taacactttc
    14221 gtcctacatt gatccccccc tctgaagtac agtttttact gtcttaaata aaattttaaa
    14281 atctaacccc atactccaat tttttatata ttccgtgtca agttttgcta cttcttcaaa
    14341 atcagtaata tcacttctac cacttacctg ccacattcca gtaattcctg gcttgatagc
    14401 aattcttgca cgatgatgat aatcatattc ttcatactct gatttaaggc atggtcgaaa
    14461 tcctataagg ctcatctttc ctgttagaac gttgaaaaat tgagggaatt catctaaaga
    14521 cgtggatcta ataaattgac cgattcctgt cttttttgtt ccatctggaa gtattttatt
    14581 tccgataatt cttggatcaa actccatctt aaacataaga ttattgctca tcttattttc
    14641 tttcattaat tctacttttc tttcttctgc atccatatac atacttctaa acttatacat
    14701 cttgaacggt ttaccattct gacctatacg ttcttgtgca aagaaaattg ggcctggtga
    14761 attaatataa ataagtggag caataaagat aaaaataatt cccgttgcaa tacatccaac
    14821 aatacctgca agaatatcaa ttgttcgttt tataaatgcc tgttgagttg tcataacatt
    14881 gatacttgtt gtaagtactg tatattctcc tatacgacca atagattgtt ttcccaaagc
    14941 actatctgat acttttgcaa gattcaaatg tacagtaagg cccatttcag agcatcgttc
    15001 aataaattct ttcatacacg aagtactttt attcaaaata ataaagactt catctaccca
    15061 tccctgacat aagtaatccg ctgcattttt ggaatcagaa acaactgtca ctccctcaac
    15121 atcttcacca atcatgcttt tatctatgat aatgacacca tttattttat acattttata
    15181 gttatgctct ttcacattac gaataactac ttcagcaata ctactagatg taactataat
    15241 aagtgatttg ttcccctcat ttttcatttt atgtttcaag taatgtttcc ataagaggcg
    15301 agttatatat gtaattacaa cgtataaacc tcccatcaag aaaagaacga ctctagaata
    15361 atcatttcca ccctgaacac taatgagata caaacttcct aacagcacca acataatcgc
    15421 ttgctttaca gaagaagcaa attctatata gtaccctctt tttaatacac ctctatatgc
    15481 ttcaaacatg aaaataacta aaagatctgc cagttcaatg aagactgcca tgttttgata
    15541 cattggaatc acataaggat tccaatctac ctggcgtaag acatacgata gataaaaagc
    15601 aagctggata cacaataaat ctaaaataat aaaatcaata tgtttaaccc atccccttga
    15661 acttttcttg tacattcctt tttactcccc tctttttaat aaaataaatt gtattacttg
    15721 ttttctctcc taaatatctt tctgaaggat tattgactcg acaaattggc ttgtggatat
    15781 tcttatatat agaacatccg taagccaact taaaactcct taacaaaatt tttttactca
    15841 tattgtagat caaaacaagt atccaagaaa tcatatttta tttctttttt ctgcttactc
    15901 aacaacagct aaaagaaaaa tcatcataaa caaattcaac taagccaacg atccccttgt
    15961 gaaatcaagt tttttcttga tttacgaata aagagctaaa ataaaccaaa cttcttcttt
    16021 tttacctctt catagactgg ataactgatt tcatccccgt tgatcagatc ctttgcgact
    16081 tgtttcatct gtactacttt ttccttacca aagtcctttg caatctgctc atagcactct
    16141 tttaagtaaa aggtgcgctt agagacccca tgggcatcag aagcagccat ctgcacgaga
    16201 ttatgtttga ccatcgtttt ggctgttttc tggatgtctt tgccaaatac cccaacataa
    16261 cttggcgcag tgagttgggc caaacatccc atatctagga acggaagcaa atgatttggg
    16321 tcttcgcgaa aatgcacgtt gcgttctgga tggacgatta ctggtgtctt tcctagttct
    16381 aacaactcaa aaaaaagccg ttctgcatat aacggcactt ccagtgtcgg aaattcgatc
    16441 agaagatatg tatcatctaa atctgtaaat aatatttcat ctcggtggat gtcttcgatg
    16501 agcgttccgg taatacgtac ttcttgtcct tccaataacg tcaaaggcaa ctgtcttttc
    16561 tctaattcgg cttgtaacga agcgactaga gaaatgactt gtgatttttc attgctgtat
    16621 tttccattat tgtggtgtgg tgtgcataaa atatgcgtga tgccttgctg aatcgctttt
    16681 tcagccattg caatacttgc ttctaagctt tctgccccgt catcgattcc tggtaggata
    16741 tggcaatgta gatcgatcat ttctcttgtc tcctctcttc ttattcctta atttccgtag
    16801 taataaccag catctttgct atgttctgct ccgttgtaca caacacctaa gactcgtgct
    16861 tgtaccatct ccagcagttc ttttgcttta gtcaaggatt ctttacgtga catattttca
    16921 cgtacgacca ataaagtgcc atccgttttt aaagacatga tctgtgcatc tgttacggct
    16981 actactggtg gcatatcgaa tatcaccacg tcaaataact gtcttgcttc ggataggatc
    17041 tgatccattc ttggcgagct taacaattct gatgggttgg gtggcttagg tccactaggc
    17101 aaaatcgaca agttctcgac tggcgttcgt tggatcacat ctgctacact tcctgatgaa
    17161 ctaagtgctg tacttaatcc actggcattg ttcagctgga atgtcttata gacgacgggt
    17221 ttacgtaaat ctgcatcgac tagtagaact cgttgacctg atttagcaaa aacgactgca
    17281 atgtttgctg cagtggtgga tttcccttct ccaggacctg atgaagtcac aacaatcgtt
    17341 ttgatttgct gaccagctgc ggaggcaaac tggatattcg tccgaatcgt acgatattgt
    17401 tcagcgattg gtgaagaggg attggtgagt gtgaccaaac tgactgcatg agtttgggct
    17461 gctttttgtt tctgtgttcg tgccattttc tttcctccta gactcttgag cggcttctgc
    17521 gtgatggcgc tgttttatcg tttgtagctt ttggttgtgt ctgagctggt ccttttttac
    17581 ggataccagc attcaattct ttcgctgaca tttctggaac tgttcctaag attgggaatc
    17641 ctaatgtatc tgtcacatat ttttcatctt tcactgtccg atcgagtaat tccaataaga
    17701 atgccagacc tacacctacc atcattccta acattaagcc agtcattaaa ttcaatttat
    17761 tatttggcga aacaggtgtc gtattggcaa ctgcacctga aatgatcgag attttatcaa
    17821 cattcatcac atcttttgcg ttctcttgga aaacttgtga agttgtgtta gcgatctgtt
    17881 gagcagccac tgcattcgta cttattgcct gaatcgagaa catttgtgaa ttttctgcct
    17941 gattaactga gatggcatct ttgatttgtt cagcagtcat tttcacattg tcttctgttt
    18001 ctaaacgatc tttgacttca ttgagcacta aatcactgac gatcatatct ttatacgtat
    18061 tgatcatttg caggttcgta ttgacatcat tgacatttgc agtgtctgat tgtggcagtg
    18121 tcacgatcaa ttgtgcttgt gaactgtatt ttggtgtcaa gatgaaaaat gttacgattc
    18181 ctgagatggc caagccagca aacattgaga tgatgattat taccaagtgt ttgcgtaatg
    18241 tttcaaaaat ttctttcaag ctgattgtct cttccatttt ttctccactt tcctatttat
    18301 tctctagatt catttgatct tttaattctt ttttcacacg atcaagttct tgatcactga
    18361 ctttttgata ggagatatta tcttgcatga agccttctcc ttgcagctga tcttgcttaa
    18421 tcgtaccaaa tgcctcccga taatctaaag caattttttt catttcatca aagttcatgt
    18481 ctgttttcat attcgactct agagcattca aaacggattg atagttgctg acaccgttta
    18541 gactcaatac ttttttcgct acgccttcta cgatctttct ttggcgccct tgtctaccgt
    18601 aatcaccatt tgggtcttca taacgcatac gagaataaga taatgcctga tccccgttca
    18661 atgtaatttt accgattgga aagtcatagc catcttgtga gaaagtgagg tcattattga
    18721 cttcgatacc accaactgca tcaacgagtt cctttagccc tttcatattg atagagacat
    18781 agtgatcgat tgggatgtct acatattttt gtacggtatc catcgccatg gcagctccgc
    18841 cgaatgcgta agcgtggttg atcttgtctt ttgtgtcacg acctacgatg tcgacatacg
    18901 tatcacgagg aatgctgacg atcgttgtct gtttgtcttc aggactgact gtggcaacca
    18961 tcatcgtatc tgatcttcct tgatcgaccc gacctaaatc tccagtatca atccccatca
    19021 atagaacaga gaaagattct tgtttgtcca gatcaactgg tttcgttcgt tctccttggg
    19081 ttcgttccac tgattcgtaa gttttctcaa tagaatgtga gagatccaga tataattttg
    19141 ctcctactcc tacaattgct aatactaata cgataagaac tgctaaaata atcagaaata
    19201 tttttttccc tcttgatttt cttcttcgtc ttgccatagt ttcctccgtt tgctaacctt
    19261 gcttgaatca acgttttaac tgtcaatagc ttatattgct atagcccatt tgctcagcaa
    19321 cagtttgtgc ttttgttgcg tatgctgcgc ttattttttc attccggatc tgctctattt
    19381 gactgagcac cgtcaaatat tgatcgtaag tagcggtggc agtcacttga ccatccttta
    19441 acatcgtatc gaataactga tctagttgcg tgacttgcgc gatctgaata tcagcgaatc
    19501 ctagatattg cataacaacc gttttccaag gactatcttt aaaaaagctc atattttcac
    19561 gtacacgagc gacatctgca cttgtcacct tttctttgat gatgacatcg tctacagctt
    19621 gctgccagtt tgatacattt ttagtaaata aatcgttgac agctgtctgg atcttcagtt
    19681 ttgattctgc actatctaac tgtgtcacga ttgctttctt ctcatcttgg attgcaacag
    19741 cttctttagg caattctgat tctttgatgt cgtaatcatc tgctgaaagt ttgacagagg
    19801 atagcttatt tgacaaactt gtgattgttt cttctgttat ttcagggttt agaaaaattt
    19861 tttcttttgt actatacagc ttgtctactt cttttgataa agaagtcaag gtgtcttttt
    19921 gattggtgat ggcagattct gcataattga tccgttgctg atgttgccgc tgattattga
    19981 tatggtatcc aaacaaacag atcgcaatag cacctgcacc taccgccaca gcagtcaatg
    20041 acttgacgaa tggcttttcc atagattcac tcctaagtat tgatgataga taaattaaga
    20101 tataattcac ttacataaaa atgacagctt tttatttaaa aaaacataat taaactaata
    20161 tattcacaga aatatttgta aacaagtttt ccctatataa tcataccaca aactgttttc
    20221 ttgactaggg caatttacga tttaaaagta aataaaacat taataagata aaaattaatc
    20281 gatttcattt ttatttccat aattttcata ggtgttttta aaagttacac aaaaaataga
    20341 ataacaaaaa aattaacatt gaattaataa ta
//
LOCUS       DACBZK010000048        20181 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.050, whole genome shotgun sequence.
ACCESSION   DACBZK010000048 DACBZK010000000
VERSION     DACBZK010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20181
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.050"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            208..1014
                     /gene="proB"
                     /locus_tag="IVD66_001847"
     CDS             208..1014
                     /gene="proB"
                     /locus_tag="IVD66_001847"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HAP6146052.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1011..2258
                     /locus_tag="IVD66_001848"
     CDS             1011..2258
                     /locus_tag="IVD66_001848"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HAP6146053.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2334..2678
                     /locus_tag="IVD66_001849"
     CDS             2334..2678
                     /locus_tag="IVD66_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146054.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2795..3121)
                     /locus_tag="IVD66_001850"
     CDS             complement(2795..3121)
                     /locus_tag="IVD66_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146055.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3494..4696)
                     /locus_tag="IVD66_001851"
     CDS             complement(3494..4696)
                     /locus_tag="IVD66_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6146056.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4813..5328
                     /locus_tag="IVD66_001852"
     CDS             4813..5328
                     /locus_tag="IVD66_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP6146057.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5527..5973)
                     /locus_tag="IVD66_001853"
     CDS             complement(5527..5973)
                     /locus_tag="IVD66_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAP6146058.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6020..7498)
                     /gene="msr"
                     /locus_tag="IVD66_001854"
     CDS             complement(6020..7498)
                     /gene="msr"
                     /locus_tag="IVD66_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAP6146059.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7852..8481)
                     /locus_tag="IVD66_001855"
     CDS             complement(7852..8481)
                     /locus_tag="IVD66_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAP6146060.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8465..8929)
                     /locus_tag="IVD66_001856"
     CDS             complement(8465..8929)
                     /locus_tag="IVD66_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP6146061.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9416..10684)
                     /locus_tag="IVD66_001857"
     CDS             complement(9416..10684)
                     /locus_tag="IVD66_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAP6146062.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10915..11652)
                     /locus_tag="IVD66_001858"
     CDS             complement(10915..11652)
                     /locus_tag="IVD66_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP6146063.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11719..12288)
                     /locus_tag="IVD66_001859"
     CDS             complement(11719..12288)
                     /locus_tag="IVD66_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAP6146064.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12416..13288
                     /locus_tag="IVD66_001860"
     CDS             12416..13288
                     /locus_tag="IVD66_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP6146065.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13630..14502
                     /locus_tag="IVD66_001861"
     CDS             13630..14502
                     /locus_tag="IVD66_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6146066.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14499..16457
                     /locus_tag="IVD66_001862"
     CDS             14499..16457
                     /locus_tag="IVD66_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6146067.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16708..17559)
                     /locus_tag="IVD66_001863"
     CDS             complement(16708..17559)
                     /locus_tag="IVD66_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP6146068.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKALVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17682..18149
                     /locus_tag="IVD66_001864"
     CDS             17682..18149
                     /locus_tag="IVD66_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAP6146069.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18412..18894)
                     /locus_tag="IVD66_001865"
     CDS             complement(18412..18894)
                     /locus_tag="IVD66_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP6146070.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(18994..19857)
                     /locus_tag="IVD66_001866"
     CDS             complement(18994..19857)
                     /locus_tag="IVD66_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP6146071.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         6065 a         4155 c         3665 g         6296 t
ORIGIN      
        1 tactcctatt ctaacatatc cgaggctgta aaagactttc tttacaaatt cttcaagaaa
       61 ttctgctatc ttaaagtaaa ccattaattc gttctttttc caaacgactg caagttgtac
      121 aaaaaaacta ttttttacat gactttactc gtcaaaacaa gtagaataga acgaaattaa
      181 tgagtggata tttgattgag gtgtcacatg cgtaaagaaa ttaaaaatgc aaaacgaatt
      241 attgtcaaag taggaacaag tacattgatt tatcccaatg gaaatatcaa tcttgcggca
      301 atcgatcagt tagcttttgt cctttctgat cttagaaatc ggggaaagga agtgatctta
      361 gtctcatcag gagctgtagg cgttggtatg cataaattac atttgtcaga acgtccgact
      421 ttgattcctg aacagcaagc tgcggcggct gttggtcaag ccgaactgat gaatatctat
      481 aatcaaagat tcagtgtata taatcaacag acggcacaga tcctcgtgac aagagacgtg
      541 gtagattatc ctgaaagtcg taaaaatgtg aggaatacat tggaacagct tttgattatg
      601 gacacgatcc ctatcgtgaa cgaaaacgat actgtagcag tggatgaatt agatcatctg
      661 acaaaatttg gcgataatga tcagctgtca gccatcatgg caaaacttgt cgcggcagac
      721 cttttgatcg tcctttctga tatcgacggg ttttattcag ataatccgac tacaaatccc
      781 gaggctcaga tgtatcgcta tatcgataaa atcgatgaaa agattctggc acaagcaggt
      841 ggtgctggta gcacatttgg aacaggcggt atgcagagta aattaaaagc cgcttctagg
      901 atatttgaag caaacagcgc aatgatttta gcaaatggaa aaaatccggc aattattttt
      961 gatattcttg caggaaaaga agtaggtact ttatttaagg aggacttgaa atgactgact
     1021 tgatgcaatt aggacaacag gcaaaagata gcgcgcaaca actagcactt atgcctacaa
     1081 accgcaaaaa tgagctactt gttcaaatgg cacaaaccat caaaaagaat caacaagcga
     1141 tcattgaagc aaatcataaa gacttagaaa aagcagtcga aaacaatatc agtgaaacga
     1201 tgcaagaccg cttgcagctg acacctgagc gaatcaatgc catggctaca gagatcgaaa
     1261 aaattgcttc gttagacgat cctattggaa aagtagatga gatgtggacg aacaccgacg
     1321 gattgagaat cggcaaaaag cgcgtgccac taggcgtgac cggcatcatt tacgaatctc
     1381 gtccaaatgt cacgacagat gcagctagtc tagcattcaa atcagggaat gccgttatcc
     1441 ttcgcggtgg caaagaagca ttcttctcga atcaattatt agtccaatta ttgcagcaag
     1501 tactggtcag tgctggcgaa tctccttatg ccatccagtt tgtcgatgat acttctcatg
     1561 aaactgcagg acagttgatg cgattgacag aatacttaga tgtgctgatt cctcgaggcg
     1621 gagcaaaatt aatccaacga gtcaaagaac aggcaacggt acctatcatt gaaacaggta
     1681 caggaaataa tcacgtatat atcgataaag aagcacagtt atctatggca gtgaacatca
     1741 tcgtcaatgc aaaagcttcc cgtccatctg tctgtaacgc ggcagaaaca ttgctgatcc
     1801 attctgagat cgcacctttt ttcttgccag ctattgaaaa agaactggta gaacacgggg
     1861 tctctttacg tgcggatgct cgtgcgttag aatatctaga gacggctgct ttagcagaag
     1921 acacagattg ggatactgaa tatctagatt atatccttgc tgtcaaagtg gtcgattctt
     1981 tggatgaagc aattgcacat atcaatcggc ataatactaa acattcagaa acgatcgtga
     2041 cagatagtta tgcggctagt caacgtttct taaatgaagt ggacgcggcg gctgtctatg
     2101 tcaatgcctc cactcgtttt acagacggat cggtatttgg ttttggtgca gagattggta
     2161 tctctactca aaagttgcat gcccgtggtc caatggggtt aaatgaatta acttccacaa
     2221 aatatatcat ttatggcgat ggacaaatcc gcgaataatg tttcgtgtga aacattattc
     2281 ccgccttttg ccttttttct gtaaaggttc tatccaacta gaaaggtgtc aatatgtttg
     2341 aaattttaat gatttttttt atttacctta tttctctgaa tatcgctgct tttctgggag
     2401 tcggtatttt atcccttttc tttcaattca aaaaacgaag catagggagt caacgggaaa
     2461 aatggtcgca gtattttgac aaaatcgggc aaaaagggct ggttacacgc ttgcacatta
     2521 gttacatggt tgcattatgc ttattagcga caatcaatta ctattctttt ttcgatcatt
     2581 caatcgctta tacgattacg ctactgattg ctgggatttt tcacttatct tataaatatc
     2641 agctgaataa aaaccacttg aatcggactt tccgctaaaa aatatccgta cgataagtag
     2701 agtgccttga agatcggcaa aaaactgccg gactttttag aggctgtgac aaagattttg
     2761 tcacagcctc tttttccata taaacggcgt tcgcctacca gctgcctggt aaatctgttt
     2821 cctcttcgtt aagaagcgaa aatccgtcaa atgtttcgcc atcataataa cgaagcagct
     2881 catccatgga caagttcatc gttttttctt tttcttcttc cgctgattca gccagtagct
     2941 gttcccgata cacctgatac ataccagcta ttttttgctg catcgctttt ctagtttcac
     3001 cttccgcatt gattattggc aattctttga tatagccacg ataaatcaac cgatcatctg
     3061 aaaattcaat gggtaattca acgagtgtca acccgacttc ctgaaaatat tcttccagca
     3121 tctattatcc ccccattctt tttcttaaat gaattttagc ttacctactg aaaattttcc
     3181 agtttcatta ttttgagaaa aaaagggaat gtgacaaaaa tcgtgtcaca tccccttttt
     3241 ccgaataaat ggtgttcttc tgccaactcc tcaatcataa gtcacaatat tcaacaaaca
     3301 tgagaaactg ttttttgaaa ttgttccttg tgattcagag ttaaacgaca gtctcacaac
     3361 ctcttggtaa acggcgttca aaagcttgca tctgcggtaa taagcccaac caaacgaaaa
     3421 atatgagaag ctatttttgt ttggctgttc ttatgacttg atgcaggaca gctttttcac
     3481 aacctctgat ttcttattct tcttcatttg tagcaaaata attacggtga taaatgatac
     3541 aacatacact gataagaaca atggcacctg caaaataaaa cgcatagctt tcaccaatat
     3601 gttcaccaat cacacctgca ataaatggtg ctaaagctcc accgaaaaag cggacaaaac
     3661 tatagctgga cgaagcaacg tttcgttgca gacctggtat ttccatagca atcgtcgtca
     3721 acagtgtatt gataattcct tggaaaaatc ctgctaacac aatgctgatc ggtacaagga
     3781 ctggcataga agttccagct cctaataaca gcaaacaaat aatgaataag acaaatgctg
     3841 ctaaaattgt ccgataagtc gtaaacttcc gctcaagagc cggtgcaacg aaaatcgaag
     3901 caatagccag aagcacaccc cagccaaaaa atacaaaacc gacttctaat tcagaatagc
     3961 caatcaataa aaatggcgca tacgcaagta aagtaaagaa tccgaaatta tataacaatg
     4021 cgattagtcc aactgaacga agtttatgat tgcttaacgc tttgacacct tcccaaaggc
     4081 ctacttttct ctttggtttc tcagtttcag gtaaaagtac cgctagggct ataaaaccgc
     4141 aaaacatcaa aaatgctacc ccaaaaaatg gataacgcca tgaaccactg cccaagaccc
     4201 caccgactag agggccaaca gccattccgc agccaagtgc tgcttcatac atcatgattg
     4261 ctttttctgt gttaccaact aaaatactga cgatcgttgc taaagcagta gagacaaata
     4321 aagcattccc gacaccccag ccggcacgta acccaatcag cattccgata ttcccagata
     4381 atccgccaag accagcgaat acaacgatga taaacaatcc tgtcatcaat gtttttttca
     4441 aaccgatccg actagataag aaacctgtaa atagcatcac cacaccagtg actaacatgt
     4501 aactagtaaa taacagggtc gtttcagctg gcgtagcgtt taactgtgca gcaatcgttt
     4561 ttaagattgg gtctactaga cccactccca taaaagcgat catacaggta gctgctacaa
     4621 ctagcgctga acttttcccc tttgtttctt catttgtttg ttcttgtata tctatttgat
     4681 tctccaatat ttccatccct ttctctctat tagcatcata catgatttat tttacatgta
     4741 aatatgcaca tgtaaaacgt ggaaacttta ctgtgatata ataaagaaaa taagacgaga
     4801 ggtaggattt ttatgaatac tttagcctat atattattat gcgtgctttt atccaaacca
     4861 cgttctgggt atgaattgaa gcagctgatc acaatttttt gggaagccca tcacagtcag
     4921 atctatacaa cgcttgccaa gttagaccag cagggttatg tgaccgtttt ggacaaagac
     4981 gagcactctc aaaaaaagat ctaccacttg actgatgaag gacgtgctct tgtagaggaa
     5041 tggatcaaag aggaaactcc cgctcctacg caaaaagatg aatttctagc aaaaatctat
     5101 gctttttcga cgctcgataa aacaacagct actggactgc tattcactag agaacaacag
     5161 ctgaacaaaa tcatgcaaaa aaatcaaaaa aaattgaatg acctctcgct agacaagaaa
     5221 caagaatttg gacgttatgt tgtgatccag cgcagaatta tgctttgtca gcaggaactc
     5281 caatggtgtc agcaagtaag agaacaaatg cagcagtttt ttgagtaagg gataaacaga
     5341 acctttctag aaatatctat tgaagagcaa attatcttca ataaaagagc aatacagttg
     5401 gaaaagaaaa agcgatccga acgacaggcc aaaacctatc gttcggatca ctatttttct
     5461 agaactgcat tcaagagact atgacaaaaa gcatgccaag gccttttttc aaataacagt
     5521 gttccatcat tcattacttt gaattgcttt tagcacactt cttgaaagcg ggccaacgat
     5581 gatcaactgc aacggtaaag cggcaatcac attcattttc caagcattca tataagcaga
     5641 gaataattga tcaggtattc cttgttccat gatcacaccg aataaagaca tacatgtcac
     5701 cattcctaaa accatcaagc atgaaatagt taagatcatt tggaccttgc tttctggatt
     5761 tactggtagt ttaaaggcaa tttttttcgc cagcacaccg atgatgaaga catccaaaat
     5821 gaaagccacc acgaatccag gcactagacc aatcaacaaa cttgataaat gaagatcttg
     5881 atgcagccat aaattatacg cgctcatccc caagaccatc aaaaaacaca tcattgttgt
     5941 aaaaattatt ccttcttttt tatttgtagg caatctgtac cactccttta aatttgtcac
     6001 gaaaatcatc gtagcacatt taaaaatttc tcgtaagtac tttttttatt ttctgccctt
     6061 ttatttcata aacttcatca gccgtacgct cgacaaagta agaatcatga gaagtaaaca
     6121 aaatcgttcc cggatatatt tgcattagct tctctaaagc ttcgatcgtt gccatatcaa
     6181 taaaattagt cggttcatct aacagcaaca cattacttgg cttagtaaaa agcaaagcaa
     6241 tcgtcagacg ggtcgcttct cccccactta atgtacataa cggtttcgtc aaagtttcct
     6301 gagcaaaccc taagtgattc agcaaactac ggacaagcga ttctgaaaac tctgtttgtc
     6361 tcatgacaaa acgaatgatg gattcttcag atgtcatttg ataacccttt tgctgatata
     6421 cttgaaagct tactttcgga gagagaagga ttccttctcc ttgtttgcgg atatgttcta
     6481 ataaggttgt cttacctgaa ccattttcac cgacaatcgc gattttttta cctaaagaaa
     6541 actgaaaatc accatttacc agtaatgttc tcccacttct ttccaattgg acattttgtc
     6601 ccatgatggg atagcggctg tggagttcaa gagattttgg tactggaaaa cggatttgtt
     6661 tcatctgctg cggcttggtt gtttctccta ttttttggag tcttctctct aatgttttcg
     6721 cattcttttg gatggctttt tgtacactgt ctttttgttt agaggaagac aaccgatccg
     6781 gtctgatttg ttgctttttc tttttactgg acactttttc caacttttcc gcttgttttt
     6841 tcttttcttg gatcgatttt tccaatcgtt ttttctcttt catgatcgac tctgcttctc
     6901 gtagctgagt ctttttctcc aattcctttt gagtgagata ggcactataa ttccccgaaa
     6961 actctcggat ttctccgtct tttacttccc agattttcga tgctagctca tctagaaaat
     7021 agcgatcatg actaacaaaa accagcgtac cataataata acgaagctct tcaatcagtc
     7081 gatcaatact ttttctatct agatgggttg ttggctcgtc tagaagcatc ccttgttcat
     7141 aagaagaaag aagacgtatc aactcgatct ttcgttcttc ccctccgctc catttccgct
     7201 ctgaagtttc ttccagtctt aactggaaat gactggctaa ttccaaattt aggtcctttg
     7261 cttcagcgag ataggttaat tgaggcaggt agttgaaggt gatctctgtt tggattttcc
     7321 catgatcggg aaaaagttca ccggctatta gtttgagcaa agtcgattta ccgacaccat
     7381 tttctcctat gatccctata cgatcttgct gatagacacg aagagaatca atagatagtt
     7441 ctagctggtt gccaaagctg acttgtagat ttgttatatt tactgctaaa ttttccatat
     7501 gttttacact cctatttcat gtaaaacaac aattatcgat actaaaaaag agcagaaaaa
     7561 tctgtttgca aaaaaactgc atcacatctt ttcctactct gaacgaaata actatgacta
     7621 aatcaccaaa tctgtcatag ctttcaccta ttctactgtc gttcgaaaaa atggacatac
     7681 tccatccatg aaattgttgt ttatacatgt cttttgaatt tatttagttg ttattcaaaa
     7741 gttcgaaacg taatttcatc gatgcagtca tttttccgac ctcctttttt attaggttac
     7801 cacacacgat tcaaaaaaag caatagctac tgaatagtaa ctgaaaacct tttattcgaa
     7861 cgtagtgatc ttttctggtg ctaaacgaac agactcgtaa ccttcttcta ccgcttttcc
     7921 tattgataaa ataataactg gaacataacg gtctttatcc aaaccaaatg cctctgccaa
     7981 ctgatctgct tcgaatccac caattggatt tgtttcatag ccatgatcac gcgcaactaa
     8041 catgaattgc atagccgcta agctagaatc gactttgact acatcgttca tttcttctct
     8101 tgaaaaactc ttgtaataag gaatgatcgc agctaattgt tgatctctga cttcttttgg
     8161 catcttccct gattcgtaag cttggttata gatttcttcg ccatattcgt aacattgcat
     8221 atcgccaaaa atcatgacca ttgcagaaga agtatcattt tgtctcgtat tgaaacggat
     8281 caaaggacgc aagatttctt ttgcttcctc gctttcagcg accacaaagc gccatggttg
     8341 catattgaca gaagaaggtg cagtcgtcgc ttctttgatc atttccagca tttcttcgtg
     8401 tgggattttg tatgtttcat catatacgcg aacggatctt ctaccagtca taattgttga
     8461 aaaatcattt ttttgttcca ttattattaa cctctttcgt ttctgttgtt atattgcaaa
     8521 gttgggtatt caatttatct aaaagtgtta gaaattgttt catttctaca tcgctgaaag
     8581 ccggggatag cacggaacct gtatctttat ggtccatttc acaatgctcg attttcttct
     8641 gggctttttc tgttagcgct acatacactt cccggttgtt ctgaggattt ctctgacgcg
     8701 aaacatagcc atttgcttcc aataccttca gatgacgagt aactgctcct tgatcaatct
     8761 gcaacttttc ttgcaaactg ctttgtagca atggattttc ttctttcagt ctcatcatga
     8821 tctcgtatct agtaagactt ataccgatat tttcttcaaa gatctggacg attttttgat
     8881 cggctaattt gatttgatat aaaaggtgac taatctcttc taaagacata atttcctcct
     8941 ttctaataat tgactcgtca acgattgact tgtcaataat agaataaaaa aagaaaaaag
     9001 tcaaagaatc agctgtgtaa taaaaaaaac gctctcaata gaaaagtata gagaaaagaa
     9061 attttttgta gaatgaacgg aaaaaatgat aaagaaagca caacgctaaa accaagatta
     9121 ttgattctta tcaaactata gaagatagct cttctgcagt agaaaatttt acaccgccaa
     9181 aaatttccga aatcgccttt tgcaagaatc ccgtcgaata ttagaaattg gatcagtatg
     9241 cttaaacagt aataaaaaag ttatgacaag atgttgtcac aacctttttt gagtaaacgg
     9301 tgttcaaaaa cttgcatctg cggtaataag ttcaaccaaa caaaaaacat gaaaatctgt
     9361 ttttgtttgg ctgttcttac tacttgatgc agggcagctt tttcactacc tctttttaat
     9421 aaccataaaa tcctattcct tcatatctcc agcccatcgg tgttagccaa tctctttcct
     9481 tagcactcaa ggtatagtga tgggtaccag ttttttcatt tggattaaat agtcgataaa
     9541 ttggcttgga accaccagaa taaaaactta gaccttcata acgccaaccg atttttgtta
     9601 aagagttgat ctcagattgt gccattgtgt aatgatggtc tccactgtaa ggattgtata
     9661 aacggtagac aggttgtccg ctgtttggtg cttgccaagc aatcccttca tattcccagc
     9721 ctacagttgg cagataattt ttttctccgg cattcaatgt atataaatgt tctcctgtat
     9781 gacggttata cagacgatac atcggagaag ttgaagttgg tgctgtatca tactgtgtca
     9841 gattataggt ttcgattaca ttgttcaatg tagaaccata attaggcgca gtggcataac
     9901 gacctgttag ccaagccgta gcatctttgt aagagttcgt attgcttttc catgcaccgg
     9961 aatagtagta aacgcctggc tgaaaagaag tcgtcttcaa taccgttacg ttatcttgca
    10021 atgattcttt gtacgaagga tattttctaa aagcggcatt caccgtaatc cattgcccat
    10081 tcacatattc cgaagtaggc atcgtaacag attggccatt atagcttcct ttaatcccaa
    10141 atagattgta attaggggca gaagccaaag tactgttccc ccagccactt tcaacgatgg
    10201 cttgagcaat catgactgat gcatataagt cattggcact tgccaaactt tgtgcagttg
    10261 aggcaatact atcaatgaac gcttgttgag aattagcaga tgagcgagca taaaaagcat
    10321 agccagtata gttttcgaat tcagacaaat ctgcttgatg ggtatgtgtc aatgtttgcc
    10381 catctgtcaa ttggttcgtg atttcttctg cattctctgg attgttctga gcttctgctg
    10441 atgtactgtc ttcggtttgt gtttgttctg ttgtttcagt tgttggttct tcggttgaaa
    10501 ttgtattttc tgagacagta gctgactgca aagtactctc tgtatcgttt tcaattcctg
    10561 tttctgaaga actcgatgtc tgagttgcga cagtttctgt cgattcttca gctagcactg
    10621 ttgtgttggc aactgctaga tttcctaaaa gaataacgct aaataataaa ttctttgctt
    10681 tcatcttttt tctcctttga attatgaaac ttttcctaaa taacagtgta actaaaaaag
    10741 taaaagcaag tcaatgtcca tatttaaata acatttgttt ctttttgatg aatttgcttt
    10801 ttctacataa aaagacgtaa atgaagaata ttcttctcca ttcacgcctt aaattgatgg
    10861 tcgtttgaat aactatttaa caagtaattc tctttggata ttatccgtta tggattatac
    10921 ttcctgtgtc gtcggacgga taatcatgtt actgacagac atccggtctg gcgtttctat
    10981 cgcaaatgct acagcagaag ctatatcttc ggaggtcaat ccccattctt tttgcgcttc
    11041 atgaagttca agagcagcct ttttgtcgct gatggtttga tataattcag tttgaacagc
    11101 tcctggagag atgatcgtag atttgatgtt attttgccgt tgctcttgac gtaatccttc
    11161 catgattgca cggacagcaa attttgttcc gcaataaacg gcggaatcag gataaacaac
    11221 atgtcccgcc acagaatcag ttgaaatgat atgcccagat ttttgttttt ccatgattgg
    11281 aagtacggcg gaaattccat ttaacacacc catgatgttg atatcaagca tattttgcca
    11341 ttcatcacgg tgaccttcaa ctaatggagc ggttggcatg attcctgcat tattgtacaa
    11401 tacatcgatt cgaccgaact tttccatcgc taaatcgata actgcttgga cttgtgcaaa
    11461 atctcttaca tctgctgttt gaatatatag ctcagcttct ggtaaagatt cttttattgc
    11521 ttttaggcga tcttctcggc gtgcagctat aactagttta gccccttttt ctgctaatag
    11581 cttcgttgtt gcttcaccga ttccgcttga agcgcccatg atgacaatca ctttttctga
    11641 taaatcattc attctattct cctcctgttt tgaaaaatct cttgcttata ctcactatct
    11701 cttatttcat cttactgttc aaataatccg ttcgacaggt ttgacgattt tggcagggat
    11761 tcctgcaacg atggtattgt ctgggacatc tttcgtaaca gttgcattcg ctgcaacaat
    11821 ggcattctcg ccaatcgtta cgcctggcag aatagttgct cctgctccga tccaagcatt
    11881 tttcttgatg tggattggct ttactgacaa gcctcttcgt tcttttggat cggttagatg
    11941 gttcaccgtg atgaggttga cacgaggacc aatcaatact gaatcttcta aacagatgcc
    12001 acctaagtca acgaacatca cttgacgatt gataaagaca tttttcccta tactaatatg
    12061 tttgccgaaa tctgtataaa aaggcagcag aacagtcacc gtatcatcta ctttgtcact
    12121 aatgatattt tctagccgtt tgcggatatc tgctggttca tggtacccag tattcagcgc
    12181 tgctaaaggc tcttcgtttt cagcttggat ctgatggatc acttcaaaga gcggatccgt
    12241 tactcgaatc tctttattga cgatttgttt ttcgatgagg cttgtcattt tgctccctcc
    12301 ttttatcctt actttataac ggacggctta tcatgtctaa tacttataaa acatacttaa
    12361 ctattccttt taactatact tagtggtatg cttttttaaa aacaggaggg aaaaaatgga
    12421 tattcgtata ctgacgtatt ttttagcagt agctagagaa aaaaatatca gccgagcagc
    12481 aaaatctctg catatcacgc aacctactct ctcaaaacaa ctgaaagatt tagaagaaga
    12541 acttggtgtg acacttttca ctcggggctc ccgagagata cagttgacgg attctggtcg
    12601 atatctttat tcaaaaggaa aagaaatctt gtcgttggta gaaaaaacgg cgaacaattt
    12661 aacaaatgac gcaatcatct ctggagaaat ctacattggc ggaggcgaaa ctaaagcaat
    12721 ctctttcatt tctgatagcc ttcattcgtt gatcaaggcg catcctgata tccagtttca
    12781 tttatatagc gggaatgcag atgatatcat agacaaactg gatagcggat tacttgattt
    12841 tggactcgta atcgaaccga caaacaaaca aaaataccag tcatttcgac tgccagccca
    12901 agatcgttgg ggacttttga tacatcgaaa tcatccttta gcaaagcaaa ccgtcatcca
    12961 tccgcaggaa ctgaaaactg ttcctttgat catttcccgg caaacgtcag tggacagtca
    13021 actagctgaa tggctaggtt tcagcataga tcagttatcg atcgtcggaa catataactt
    13081 attgtacaat gcttctttga tggtcgataa cgggactttt ggtgcattag ctctagatgg
    13141 gatcatcaat acttatggga cggaaaaaat attcatccca ctcgatccgc cattacaagc
    13201 ttcactgaat ctcatttgga aaaaagacca gcctctttct cctgctgctc gtaaattttt
    13261 agatgtccta acggagaaat acagttaagt agagtttttt tccttcgctt tcagcttttt
    13321 aacaacgaat aagataagca aaagatccaa cgattaaata acataagttt cttaatttat
    13381 ttcttccttt tatttctgat aattccagta aattactata attataaaaa aagaattgac
    13441 aaaacataac tgtctatata aaattgatta cgttaacaat aattcgtttc atgtgactag
    13501 atcatactag gcatgaaaaa tctctgagga acatggtttc cctaggaggt ttttcgtgtc
    13561 tatttttgtt tggccgcaat caactggtct agcaaacgtg aaaaccaaat cttcaaaaag
    13621 ggtgcgcgca tgaaaatcaa aaagatcttt aatcaaaatg cagtattggt agatgacggt
    13681 ggacaggaaa aagtagctat tggaaaaggg attggatttg acagaaaaag aaatgatttg
    13741 atttttgatc gtgatgtcga acggatattt gtcatggaac cagaaggtca aatcaagttg
    13801 caaaatttac ttaatcagat tgatgaacgc tttttatttg cagcagaaac gatcattgat
    13861 catgcggaaa ctgttttgat ggaaaagttg aatgaacatg tattgatcgc tttgaccgac
    13921 cacattgctt tttctgcgga gaacattaat aacggtatcg tcatccgcaa caaactttta
    13981 agagaaatcg aagtgcttta cagtgatgaa ttcagtattg ctcaatgggc agtagagtat
    14041 ctgacaaaag agcttgggat tccatatact tatgacgaag caggatatat cgcaatccat
    14101 attcacagcg gacgaagcgg tcggaacaat aaccatcgca gtatccgtga agtgacgatt
    14161 gtatctgaca tcatccattt agtggaatca gaattggaaa cagatatcca ttcagaacca
    14221 ttttcactga attattcaag actggtgaat catttacgac tacttctaca acgaacccat
    14281 gcgcaacaat atgctgtttt agacacggaa atcgtagaaa tggtcaaacg aaaataccca
    14341 gaaagctata agatttctaa aaaaatccgt gtgttgctga ccaaagaata ccagctcgcg
    14401 atcacgaaag aagaactggg ttacttggcc atccatatcg agcgtttaag aagcgcaatc
    14461 gtacaaacaa atgttaacaa tcatgaggag gaaaaaaatt gaaagcatat ctacaacgaa
    14521 tgggacgttc ccttcaactt ccagttgcgg tcttacctgc tgctgcttta ctagtaggga
    14581 tcggaaactg gtgggcatct tatagtaacg acattgtcgc tcatttttta caagctggcg
    14641 gtaacgcagt tttaggtcaa ttacctttgc tgtttgccgt tgggttagca ctagggatgt
    14701 cagtggacaa atcaggtgct gctgccttgg caggtttggt cgcatttgaa gttccagtaa
    14761 atgttttaaa aactgattca gtagctactt tattgaatat caaaccagaa tcagttgatc
    14821 catcttttgc tcagatcagt aacgtattta ttggtattat tgccggattg attgcggcag
    14881 ctctttataa tcgtttccac gaagcaaaat taccgatggc tttatctttc tttagcggca
    14941 agcgtctagt gccaatcttg gctgcctttg tcatgttgct gatcagtgca gtgctactgc
    15001 tcgtatggcc tccggtttac tctgctttag tttcttttgc taaattcatt ttgagtttag
    15061 gctggggtgg tgcaggtctt tatggcttct tcaaccgttt actgatccct acaggattgc
    15121 atcaagcaat gaactccgtg ttctggtttg acgtagcagg aatcaatgat attggtaaat
    15181 ttttggcttc tgaaggaaca aaaggcgtaa caggaatgta tcaagctgga tttttcccaa
    15241 tcatgatgtt cgggcttcca gcaggagcat atgctattta cagaaatgca cgtccagaaa
    15301 acaaagcaaa aacagcttcc ttgatgctag cagcagcttt tgcttcattc tttactggtg
    15361 tgacagaacc acttgaattt tcatttatgt tcgttgcttg gccattatat gtcttgcatg
    15421 caattttcac tgggatttct ttagcagtga gtgcattctt ccattggaca gcaggatttg
    15481 cctttagtgc cggatttgtc gattacttcc tatctttgaa aaatccgatt gcgaatcagc
    15541 cattgatgtt gatcgtccaa ggattagtaa cagcagtgat ttactacttt ggctttaact
    15601 ttgctatcaa aaaattccat ctgatgactc ctggccgcga ggaagcagat ctttcagatg
    15661 acgatactgc aacgactaat tcagacaata aatatgcggc acaagcaagc aaaatctacg
    15721 ctgcattagg cggagccgac aatgtaactt cgatcgataa ctgtactaca cgccttcgtt
    15781 tgcaagtcaa agatacaggc ctgatcgatc aaaataaaat caaagccact ggcgtacctg
    15841 gtatgaagat catcgacgga aaaaatgcgc aagtcatcgt aggtacagaa gtacaattcg
    15901 ttgcagatga gatggcaaaa ctacatggtg gtgctgcagc acgacctgca caaacaaaca
    15961 ccgtggttaa aacagaaaca tttgccggtg aaacgatcga acaagatatt tacgctatcg
    16021 caaatgggaa actgattcca atcactgaag tttcagatga tgtattcgcg gaaaaaatga
    16081 tgggtgacgg ctatgctgta ttaccagaaa atggagaaat cttctctcca atcgctggta
    16141 cgatcacaaa cattttccca acgaaacatg ctgtcggaat ccaaacagat gctggtatcg
    16201 aagtcttgct tcatatgggc atcaacactg ttgacttaaa aggcgaacca ttcactttat
    16261 atgtagaaga aggtcaaaaa gtcgcaagag gtcaattgat tgctttagtt gatcttgccg
    16321 ctattcaatc tgcaggcaaa aacacggata tggtcgttgt attcacaaat ggcgacaaag
    16381 tccaaagctt agaaatcgaa cccgcacgtg atgtaaaagc aaatgataaa atcggctctg
    16441 tttccaacaa agcctgagcc atcgtcttcc ccagactttt ttatcgataa acaaacagga
    16501 gctgagacaa aaatcttgtc tcagctcctt tttccgaata aaaacggcgt tctcctgcca
    16561 actccgcggt aataagtcca gctaaacgaa acatatgaag agctattttt tatttgactc
    16621 ttcttattac ttgatgcaga acagcttttt cacaaaattt ttcttcatac tcaaaactaa
    16681 tcggcttttt cacaacctct ttatacatta ttcctgatcc aatatttctt ttaatgctgc
    16741 ttcaagagaa gttaatggtt ttcccaatac tttttctaaa tcatcagagg aaatagctaa
    16801 ctgatccttt ttaatatcat gttggatcgc taaaaacatg tcagctgctt cttgagggaa
    16861 tccggcttct tttagatttt cgacaaacgc tgcatcactt gcttcaataa tttctaactc
    16921 tttacctgtc gcacgctcta atgccttggc taattcttca tagtcagtta gattgccgga
    16981 taattctaag atttctggag agtcactttc tactagtgct tttgctgcag cttctgcata
    17041 ttcacgtttc aatgcccaac ctgtttttcc atttcctgca gcataaacga attgaccagt
    17101 ttttaaagcc tgcccaatga taggtaattc attctctaca taccaattat tccgtaaaaa
    17161 tgtatgggaa atacctgaat ccttaatcat tttttcagtg aattggtgat ctggcgctaa
    17221 tacactgatc gagtgatcgg catctgcaaa acttgtataa gcgatataag ataccccagc
    17281 tgcttgtgct gccttcacta cattcttatg ttcggcttga cgatttcctg gaacgccaga
    17341 gacaaaaagc aatcgatcta ttcctttcaa cgcttctttc attgagtcta aatcatcata
    17401 atcaccaata cgtatattaa atccagcttc tttcagtgct tctccttttt cttcactacg
    17461 tactagtaca tagatttcat tttgtggaac catctttttt aagaattcca gcgcataacc
    17521 accaaaacct ccagttgctc ctgttactaa ataatgcata tttgccactc cctattcttt
    17581 ttatttgtta agatttacag ctgtacattt ataaattaca cctttatcat aaagagtgtg
    17641 gtaagataag tcaagcaaaa aaaatgaaag gatgacaact gatgaagtat tctctgcaat
    17701 ttagtgatgc aatccatgta cttgcctata ttgaaatgtt tcaagatacc cgatcacttt
    17761 ctagtgagat gattgccagt agtatcgaaa caaatgcagc aaatgtacgt aaaatcatga
    17821 gtcagctcaa aaaatccggt ttgatcttta caaaaaccgg aaaaccgcag ccttcccttg
    17881 ccaaaagtcc agatcagatt tctttactag atgtctatcg cagcatcgaa ggtaatacac
    17941 agcttatcca agtcgatcca aaaacaaatc caaattgcgt cgttggtgcg aatatccaag
    18001 aagctttaga agaaagctac gctcggctgc agaaaaaggc agaagaagaa atggctaaga
    18061 tcacacttga tagtctgata cataaaatag ccgttttgga aaaagaaaaa agaccagaaa
    18121 acacaggcct cgtagagaga tttttataat tctctctact gtgcctgcat ttttctgatc
    18181 ggaatcgtct acataaattc ttttattctc cgggggacaa aagccttgtc atgccccttt
    18241 ttcctctcta atgctcaggt caaagcgctg aagtcatgac gtcttgataa acggtgttca
    18301 agtagctgac cctcggcatt agttctgaaa aatgcaaaat atggaaagct atttcccatt
    18361 tttcctctct aatgctcagg tcaaagcgct actttcacga cctctatatt atcatggttt
    18421 attgactacc ggtatccaga tttctcccat atatttcccg ttggtaactc ccatttcgac
    18481 tacagcattt ggacccccaa cataggcgta atcttctact tctcttaaaa catgcccaaa
    18541 ggccgtattc gtcaaatcat ttcttaattc ttcaggcgat tctgctaaag cgcttacaac
    18601 aagatacgtt ccttttggga atgggatgat tcgcgtagtg tttggaacat cctgactcgt
    18661 ttgaacaccg acatagtaca tcattttccc gttatagggt tcgttgactg taaagaaata
    18721 atgattttca gcagcttgtt tcaatgcatc tattgttcca ttaccgataa ctttttgctc
    18781 aaatgcttgt ttctctgcag ccaaaccgac aaaatccgta ttgctactct tcaattccac
    18841 accaataccc gtcaccgtaa aatctggttt ttcttcgatc ctatactttg ccatttctcc
    18901 caccctttct attatattaa gttcatctta cataaaatta aagggaaatg acacgattac
    18961 gctctttttt ctagggatat ttttattttt taactatttt tttgctttca ctgcaatcca
    19021 aatctcactg taaacattac tgaaatcctc tccccatttt gtaaaagaga tctcgggagc
    19081 ttcgactaac ccataatctg aagaaggaag ccattctgca tagattttcc cccaagtatc
    19141 ttgtaaagtt tggggaaatg gccctttatt aggaaaaatg gcccaagtgt gttcttctat
    19201 agcaagcatt tctaaatcag cgtacggatt ttcttttgtc gtagcaaagc caatcatgtg
    19261 catcaaactg cccttttctt ccaagcggtc tccatcaaat ccataagaaa cgttgattac
    19321 ttgatttgga tataaatctc ctaacttatg catctcttcc ctttgagtct ccgtgatcgt
    19381 ctgcgctaac ttttgtattt cttgattgac tccttcaaat ttgacaggaa cttttttcgc
    19441 cacacctgcc acataaaact gttctttctt ttcgatacga aattccatcg attttcctcc
    19501 tctgacatca ataaaaaatg tcaagcgtgg aaaagatttt tgtatgccgt atctgctgat
    19561 ttctgaaggc agatatcctg accaatcacg aaaagctctt gaaaaacctt cgactgtttc
    19621 atatccatat ctaaacgccg tttctgtcac tcttgatcca tctagaagat cgcgattagc
    19681 caaagccaat ctacggtttt tgatatagtc cattagcgac atccctgcaa taaacgtaaa
    19741 gatgcgtttt aattgatatt cagagattcc tgtattttcg gctattattt tataggaaag
    19801 tccttctgtc aaatgttctt cgatgtaatc gatcaattgg ttcagatctt taagcatatt
    19861 tatcttcctc cttgattgcc tttttatcat attatcaaag aaagtcaatt acttgatgaa
    19921 tcaggaacca atttagtcag atgtagaaaa tgttgtatgg atctaaagaa aattctcaag
    19981 cagcgtttcg taacggataa ttggtattat ctgcctatct atgttttacc tttagaaaaa
    20041 taaattttgg ggaagacaga ttctaagtaa acaaagcggt aaaaatatct tttattccct
    20101 tagttaatcc gcttactacc tactgtacaa agcaaattgt tgttcaaact gctgatcaga
    20161 acgctgcttg gatttttctt t
//
LOCUS       DACBZK010000049        19796 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.051, whole genome shotgun sequence.
ACCESSION   DACBZK010000049 DACBZK010000000
VERSION     DACBZK010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.051"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            121..768
                     /locus_tag="IVD66_001867"
     CDS             121..768
                     /locus_tag="IVD66_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HAP6146072.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            852..1796
                     /locus_tag="IVD66_001868"
     CDS             852..1796
                     /locus_tag="IVD66_001868"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HAP6146073.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            1931..3382
                     /locus_tag="IVD66_001869"
     CDS             1931..3382
                     /locus_tag="IVD66_001869"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HAP6146074.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            3403..4239
                     /locus_tag="IVD66_001870"
     CDS             3403..4239
                     /locus_tag="IVD66_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAP6146075.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            4239..4898
                     /locus_tag="IVD66_001871"
     CDS             4239..4898
                     /locus_tag="IVD66_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP6146076.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            5024..5713
                     /locus_tag="IVD66_001872"
     CDS             5024..5713
                     /locus_tag="IVD66_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146077.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            5719..6675
                     /locus_tag="IVD66_001873"
     CDS             5719..6675
                     /locus_tag="IVD66_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HAP6146078.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            6719..7231
                     /locus_tag="IVD66_001874"
     CDS             6719..7231
                     /locus_tag="IVD66_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6146079.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(7487..8035)
                     /locus_tag="IVD66_001875"
     CDS             complement(7487..8035)
                     /locus_tag="IVD66_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6146080.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(8124..9305)
                     /locus_tag="IVD66_001876"
     CDS             complement(8124..9305)
                     /locus_tag="IVD66_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HAP6146081.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(9541..11049)
                     /locus_tag="IVD66_001877"
     CDS             complement(9541..11049)
                     /locus_tag="IVD66_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HAP6146082.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            11208..11399
                     /locus_tag="IVD66_001878"
     CDS             11208..11399
                     /locus_tag="IVD66_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146083.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            11602..12519
                     /locus_tag="IVD66_001879"
     CDS             11602..12519
                     /locus_tag="IVD66_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HAP6146084.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            12512..13585
                     /locus_tag="IVD66_001880"
     CDS             12512..13585
                     /locus_tag="IVD66_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146085.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            13733..14251
                     /locus_tag="IVD66_001881"
     CDS             13733..14251
                     /locus_tag="IVD66_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146086.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            14232..14624
                     /locus_tag="IVD66_001882"
     CDS             14232..14624
                     /locus_tag="IVD66_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HAP6146087.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            14700..15635
                     /locus_tag="IVD66_001883"
     CDS             14700..15635
                     /locus_tag="IVD66_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HAP6146088.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            15768..16547
                     /locus_tag="IVD66_001884"
     CDS             15768..16547
                     /locus_tag="IVD66_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HAP6146089.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            16540..16857
                     /locus_tag="IVD66_001885"
     CDS             16540..16857
                     /locus_tag="IVD66_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAP6146090.1"
                     /translation="MTKLYLLLLVVCLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            17101..18711
                     /locus_tag="IVD66_001886"
     CDS             17101..18711
                     /locus_tag="IVD66_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP6146091.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKNDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            18868..19716
                     /locus_tag="IVD66_001887"
     CDS             18868..19716
                     /locus_tag="IVD66_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP6146092.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT         6393 a         3533 c         3973 g         5897 t
ORIGIN      
        1 tctttttctt tatattttca taataaaagt ttggttcttt aatttttaaa catgacagaa
       61 aattttttct tcgttatact tgtaatagaa tactatttta taacaaaggg gatcgaatca
      121 atgaaaaaaa ctgttattta tactagttta tttgcagctt tgtttttagc tgcttgtcaa
      181 tcaaatacca atcaaggcac atctgggaat acgtcttcca gtagcgaaca gcgctcttca
      241 caggtatcgg actcctcaac aaaagcaagc acatcttcgt ctagccagac aaaaagttct
      301 agtgaagcaa gtactcagtc agatatcaaa gtgtctgcag ctcgtgcgat cgaattgttc
      361 caagataaat acccagatac tgcaattact agtttggaat tagatagtga ttggggatct
      421 tacttctaca agatagaagg tgtcgatgat caaaaagaat acgaagcaag aattgatgct
      481 caaaatgaaa aaatggagac agagaatcca gaaactctag atcgagatga acaaaatggt
      541 caaaagaaaa aagaagatgg tctggatgtt gataaattga tcacgattga ggaagcagca
      601 aaaatcgccg tcgacaaagt aggaagcggt acggcaacag attgggattt ggataaagat
      661 ttaggtacta cttattggga agtcaaagta aaagacggca atcaaagtac atcagtcaag
      721 atcaatagcc aaacaggcga agtactgtca actgaacaag atgattaaga atttcttcgg
      781 aaaacaagag ttgatttttc ttttagtcat gatacactag acaaaataac ttgtttgaag
      841 gagcgattta cttgagttta gaaacgacct ttgccaatca tatctttgcc aatcctttga
      901 tgaatgcatc tggtgtccac tgcatgacta cccaggaatt agatgaactg gctcattcag
      961 aagcaggagc atttatcact aagagctgta cgatcaatga acgaaaagga aatcccgaac
     1021 cacgctattt tgatgttcct ttagggagta tcaattctat gggacttcca aacttaggtt
     1081 tttcttatta tctagagtat gctcttgcgt atgaaaaagt gcaggaaaac caaaatcaac
     1141 cgttattttt ttccattgcc gggatgagtg tccaggaaaa cttggaaatg cttgagaaaa
     1201 tagaaaaaag tgggtttaat gggatcactg aattaaattt atcttgtccc aatgtgcctg
     1261 gaaaaccaca actagcttac gattttgagg ccacttatga aacactgaaa gaagtattca
     1321 gcatcttttc taagccgcta ggaatcaaat tgcctcctta ttttgatttt gctcattttg
     1381 atcagatggc tgatatcttg aatcagtttc cattgaccta tgtcaatgct atcaacagtg
     1441 tgggcaatgg tttgtatatc gatacagaac aagaagcagt agtcatcaaa ccaaaagaag
     1501 ggttcggcgg cattggcgga gagtatatca agccgactgc tttggcgaat gttcgcgctt
     1561 tttatacacg tttgaaacca gaaatccaaa tcattggtac aggtgggatt cggacaggac
     1621 aagatgcatt tgaacatctg ctatgtggcg caagcatgtt acagattggt accgagcttc
     1681 ataaagaagg gccggaaatt ttttctagaa tcataaaaga attaacgcag attatgtcag
     1741 aaaaaggata tacgtcaatt gacgaattta aaggcaaatt acgcaccatt tcatagcaaa
     1801 gagacgaagg tcatgattga tcttcgtctt tttttataaa aaacactcgt ctgttcattc
     1861 ctgtgcaagc gtactcattg tatgttagac gaacttgtgg gaaaataaca gaggcaaaaa
     1921 ggaggataat atgaatgatg caacagaatt agcaaaagag cttaaagaaa aagaatttag
     1981 ttttcaagaa ctagttacgg atatacagaa aaaaataaag aagcaaaatc atgaattgaa
     2041 tgcgtttgtc gcgcttgaac cattcgagag taattcccac gagctattga ttccccagtc
     2101 agaaaaaggg ccattggctg gtatcccatt tcctttaaaa atgctcggtc aagaaaaaaa
     2161 gggatggcta gctacttcag gatctcgttt atttgaaaca caccgagctt ctcatacatc
     2221 taattatgtg cggcaagcag aagcgatagg tctagttcct tttggacaaa ccaatgcgcc
     2281 agagtttggt ttcaaaaata ttacagaccc agtcatctat ggcccagcaa gaaacccttg
     2341 gaaccttgaa tgtacaccgg gcggatcaag tggaggagct gctgctgcag tttcatcagg
     2401 aatcgttcct ttagctggtg ctagtgatgg cggtggttct attagaatac ccgcttcgtt
     2461 ttgcggattg attgggctga aaccttcgcg agggacgatg ccagttggtc catatgcttg
     2521 gagaggatgg caaggagctg ctattgattt cggcttgaca gtttctatga gagacacgga
     2581 ggctttattt tatgggatga gaagtatcca ttccggtgcg ccatatcaag tatcgccagt
     2641 tgagtggcaa acacatccaa gaaaaaaacg gttgaagata gctttttgtg ttgattcacc
     2701 gatccactca cagattagtg aagaggcagt acttgctgta aaaaaagctg tagatttcct
     2761 tggaaaagaa gggcatgatt tgacagagat tccttaccca ctagatggtc gtaaactgat
     2821 cacgtcttat tatcagatga atggcgcaga aacagcagca atgatccgct cgattgaaac
     2881 aggcatccag cgagctgtca gaaaagaaga acttgaaccc atttcttgga ctttgttcca
     2941 atatggtcag aagctctctg ccgctactta catcgattct ctgcatgtat gggatgaagc
     3001 agcaattgtc atggaaaacc tacatcaaga atacgatcta ttcctttcac caacgactgc
     3061 atttaccgcc cctaaaatca gcgaagattt gcaaagtgat gcgataagag cacagatgga
     3121 acacatcagt gattgttctg aagtagaagg tttagacgtt gtttcttcca tgtttgagga
     3181 gagcttgaag atcacacctt atacacagtt ggctaatctg actggacaac cagcaatcag
     3241 cttgcctact catttgacaa aagaaaacat gcctctagga atccaattta tggctgccag
     3301 aggaagagaa gatttgctat ttcaaatcgg ctatctattt gaagcaaatc atcagttcca
     3361 tttaccaaat ccatggaaat agcagaaaca aggagaagaa gaatgaagaa aaaaagattg
     3421 tttgctctaa taactagtgc cttttttatt ttaagcgctt gcggtacagc tgccgctaat
     3481 caggaagata acagctggag taatgtagaa aaaaagaaag aattagtagt agcgacttct
     3541 ggcacactgt ttcccgcatc ttattataat gatcaaaatg aattagttgg ttatgatgta
     3601 gatttggcaa aagaggtggc taaacggtta aatgtcaaaa tctcctttaa agaatacaac
     3661 gtggatggac aaatcacttc tgtttcaaaa agagaatcag attttgctgc gaacgatttt
     3721 ggtatcacaa aagaaagaga aaaaaaattc tccctttcag agactttcaa atattcattt
     3781 gacagtatga tcgtacgaaa aaaagatgat tcaggaatcc actcacttga agatcttaaa
     3841 gggaaaaaag cagctggcga acccaatact agctatatgc gtttagcgga aaaacacgga
     3901 gctaaattag tcacatatga caatgccacg aatgatcagt atttaagcga tgtagcaaat
     3961 ggtcgaacag atgttattct aaatgattat tatctgcaga aaatggccgt atctgcttta
     4021 ccagatatcc ctgtaaaaat actggagaac gtttatttca atgaaaacga aagtggtttt
     4081 ttattgaaag aaggaaatga tgctctgaaa aagaaaatcg atggcgtatt aaaagagatg
     4141 aaagaagatg ggacgacaaa gaaaatatct gaaaaatatt ttcaaactga tgtttcagtc
     4201 aaaccgaaag aaacgatggc tgagtcggtg agtgagtgat gtactttcct ctaattgatt
     4261 tttccctcat gtggacttca cttcctttcg tactgcaagg cttggtatac acattaggga
     4321 ttggcttcgt gtcgtttctt ttaggaaatc tggtagggtt gcttttgaca gttttaggtc
     4381 ttttggattg gctgcctctg aatgtattta ttcgttttta tttatcgttc tttagaggca
     4441 ttcccgcact agtcctgctg tttctgttat attttgggtt accttatcaa ttaagtgcct
     4501 taacggcttc agtcatctgc tttacgatta ccagcagtgc atttattggt gaaatctatc
     4561 gaggatcact agcaggcgtt tcttcaggtc agtgggacgc tggtttagct tctggttttt
     4621 ctttctttgg ggtattgaaa tatatcgttt tgccgcaagc ttttcgaatc tcagtaccgg
     4681 cactcagtaa cgtagctatg gatctagtga aaggtacttc gttagcagca acaatcacag
     4741 tgccagaaat atttcaaaaa gcaaagatca taggcggtcg gacattcgat tatttttctc
     4801 tctatatttt agttgcactg atttattggg tcatttgtat cgggatcgaa aaagtgcaac
     4861 agtatttaga aaaacgttct atgcatcagt caatctgaaa aatagaaatg gtgctagcgt
     4921 ggctggcacc atttctattt tttgtttctt gtatattctg cctagtattt taaaaccatt
     4981 tcatgtaaaa tgtaaatcga aaatatgttc ggaggtagaa aacatgaaga ccccgctaac
     5041 catcgaaata gaatcctcgt tataccaata ttgcatcgag caaggcggct tggttgtaga
     5101 agaagtcacg atgcctgatg accaaggaat tgtagatacg cttagctgct tgacaaaatt
     5161 tgatggaagc cgagaatggc gatgctatga gctgaaagtg acaaaagcag attttcgctc
     5221 tacagccaaa ctgtcatttg ttggacatta taattatttt gttttaccaa gtaaactata
     5281 tgaagaagta aaaactgaaa tccctacagg aataggtgtt ttagtgtatc gtccgtacac
     5341 ggttgaagag gagatgcctg cctctggtac atttctgatt gcgaaaaaag cagcaaagaa
     5401 agagcttgct gtaccggaag aagctttgac aaaccgcttc atggcttctt tattcaggga
     5461 agtaagaaaa gcaaagcaaa tggagcgagg cgtaaaatat tttccaacag atcaattgta
     5521 caaagaattg aaaagacgtt cagaaaatca agatccattt tctaacgaac gatattatga
     5581 acggttttta gaggaaatag ctagtcaggc aatcaatgag ttgcaagaag aagttatcgc
     5641 gcttcagcat gattatgaat atttgaggca acaacagcag atccgtcggt tgcctacaga
     5701 gccattggag tgaaaaatat gtactatcct tatttaagag gaaaacaatt tgacctatta
     5761 gcattaaaag aagcactgtc gcgaggattg ctctccaata aaatccaacc agtgatcgaa
     5821 ccagtacgtg attccgctac gcttaaaaat gtgatcgaat tatttcaaaa aaagcaccat
     5881 cgaatcgctg tgatccaaaa tccccaagta ggacaattca aattattcga tcagcatgtg
     5941 cacagttgga cagtcaaaga aaatagctct gtcgtccctg cacagatctt aacgccagaa
     6001 aatctcagtg aagtactgga ttcacctcca gcgtttcttg ttttcgatgg acagcactac
     6061 ccaaaagata cagaggtgtg gaaacagttg gcaggagttg attcgaaatt tttgatacca
     6121 gatactagtc gctttcgcat ctggctgccc gaaaacaaaa ttgtgatccg tgactctttt
     6181 caaacgagaa agcatgttga aagttatgca gataaaacag atgacttttt tagtgatgac
     6241 tatctttttt tccacgcaga cggatatatt ggattttctg atttcacgat cgaaggtagc
     6301 cgttatttcg ataaagggtt ccctagccga gcgcttgcta tccatctaac gtatattgat
     6361 gcttacggca atatacgcgt gaaacatttt gtctctgaca gtaacgactc tgctaaagac
     6421 caagcattga agtttcttga agcaggagat aaaatgaaaa aatggatcat gcgtcaccat
     6481 catcaactct tgattacttc aggaatgatt gaattattgg ctctttacca gcaacaaaaa
     6541 ttccctggac tgggagtgtt gaaaaagtgg tcacttatgc atcatttgga acttattagt
     6601 cacctgctag atcatccaaa agattggctt aaatattatt caaaagttca ggaactatat
     6661 gaagtgatcc aatgattaga taatgtaaat gaaaaaggaa tagaaaagag gaaactggat
     6721 gtatattcgg caaacaagga aagaagaagt agaagaagtg gtagaaatca ttaatgccgc
     6781 agcggatttc attgcttcgc aaggctctcc tcaatggcaa aacgggcaga aaccaacaaa
     6841 agaaacgatt ttgaacgata ttgaaagaaa agaaagctat gtattaatag tggaagatca
     6901 aattgctgga acagctgcat tagtctcaag cgtggatccc gtttacacaa aaatagatgg
     6961 tagttggaaa gaatcaactg gtccttattt atcgattcat cgtgtcgctt tagcagaaag
     7021 tactcgagga aaaaaactag caaaaccgtt cttagaacat ttgttgacga ttgcagccag
     7081 caaaaatatc caagatatcc gtatcgatac ttatccagct aatgaaccga tggaaaagac
     7141 catctattct gctggattca cttatcaagg gatgattgaa tttccttttg aacacggcga
     7201 aagaaaagca tatcaaataa tcatcaattg actataaaat catctgagca aagataaaga
     7261 cattaacact actgaaaaaa acaatcatat gatagccaag aggttgtaac agaagtggcc
     7321 agcttcaaaa aacaagaaag aatttccgaa aatgcttctc aaatttttgt ggaattttag
     7381 cgtattttac gaaatagctg ctttctgaaa ctcccttcat cgagaggtcg tgacatagct
     7441 tttgtcacga cctctcggct tatcctacga gtattattcg atacatttat atcaataatc
     7501 ctttttttat tttatctgca gcttcttgga acgctccatc gtttgacacg actaaaagtg
     7561 aggggatagc tttcaaacgt ttcaactgtg ctaaatcttc tacataaacc gccagtctgg
     7621 ctgaaatctg ttcagatgaa tctccacgtt ttttcaggcg cgattgcaat gtttctttag
     7681 agatcgtaat aaagatagga cggactaccg tcccgaaata ctcatataaa tgccaaaaac
     7741 catttgctgt caaaacggcg taacaatttc ctactgtcag tttcttttta atttctgctt
     7801 tactggaacc atatttatgt tgagcatatt ggtcccactc tgcaaactca tttcccttga
     7861 tcatctgatt gaatgtattg tcagaaacaa aataataatc ctcttgatct ttttccccag
     7921 gtcttggtga tcgattcgtg taagtaatga tcttttgttc cggctgaaaa atagcttctg
     7981 cgagtgaagt ttttccagaa ccagaaggac cgataaatac atagcaataa ttcattgtca
     8041 tttctccttt gatgattgaa caagtgaaaa agctttggaa aatatttcca aagcttttaa
     8101 aagtaacttt gcttttttgt atattatacc agcaagccag tcacaatagc acttaaaaag
     8161 ctgactaaag tcgctgttag caaaattttc aatccgtgtt ttgcgacaag atttcctttt
     8221 tcttcattta atcccttcat cgcaccagaa atgatcccga tagaagagaa gttggcaaat
     8281 gaaacgagga agacagatat aattgctgtt gtacgctcag taaaatggaa attaccattt
     8341 gctaattctg tcatagcaac aaattcattt gtaaccagtt tagtcgccat gatactaccg
     8401 gcatccactg cttctttcca tgggattccg ctgatgaagg caagaggggc aaagatgtaa
     8461 cctaggatct cttggaaagt gatgccgaat atcccgtgga agatagcatt gatcatggca
     8521 atcaaagcaa caaaaccgat aagcatagca gcaaccgtga tcgccacatg gaaaccatca
     8581 agaatgtatt ctcccaacat ttggaaaaat gtctgttctt tgttttcttc aatgatcagc
     8641 tcatcttctt tttcttctaa tacataggga tttacaattg aagccagaat ataaccgcca
     8701 aataagttca aaacaagggc agtgatcaca tatttagaat cgatcagtgc catataagat
     8761 ccgacgatcg acatagaaac tgtagacata gccgatacac tcatggtgaa caaacgtttc
     8821 tcagatagga agggtaattc cttttttatg gaaataaaaa cttccgattg tcctaaaata
     8881 gcagaagcta ctccattata agattccaat ttgcccatcc cgttgatttt acttaatcct
     8941 agaccaacag ctttcataaa taatggaaga atcttgatat agcgtagaat accgataata
     9001 gcagaaataa atacaattgg catcaatacg gaaagaaaga aaggtgcact tcctttattt
     9061 gctacaccgg caaaaacaaa gtcaacacct tgcccagcaa aagcaagaag atgatcaaac
     9121 atttttgcca atacagaaac aaccgctgta ccaaaagttg tacgtaataa tacgaaacca
     9181 agaacaagct gtaaaacgaa catcacaatt agtggtttca atttgattgc ttttttgtta
     9241 ctgctgatca aaaaagcaag ccctaatgtg acaaataaac caataatacc taataaataa
     9301 ctcaaataat cactcctatt ccaaattccg ttttatttta cctgttttgc aaataaaata
     9361 ctaatcttta gtgaaatttt cattactttt ttagagtgaa acgcattcat tttccattag
     9421 aaaataaagc gaacaaaata aaaggtttaa aaagtgtaac gtcttagtaa agtctataaa
     9481 aaaacgaaac tatcgattaa gctaatagtt tcgttttcaa catttataag taaacttttt
     9541 ctattggtaa tatagatttt cggaagggta gacaggtgcg caggtaatat cgattcctag
     9601 ttttttcaat gtttgttcat catttttatt gaccatcaca gtagagtggg cttgtgctcc
     9661 ctcaagttca gctagtttat cataagcaac ttgagcgatt ggattcgtta ctgcactgat
     9721 tgataaagcg atcaagactt cattgatgct tagtgcatcc aaagaggaat gaagtgtctt
     9781 tgatttcaat ccttgtattg tttcaagaac taatggtgac aataaaggaa tgtcatctgc
     9841 gatatgggct aaatgtttta ctgcatttaa gataactgcc gctgacgcat ccatcaatga
     9901 acttgtacgc ccggtaatga tgacttcatc tggtaattcg attgcaatca cagcagaagg
     9961 atcttttgta ggactttgcg cttgaatctt atctgcatag tcatgggcag ggactaccac
    10021 gtttcggtct tcaggacgta aaccgacttc ttccataatc agtttgattc gattaactgc
    10081 ttcttcgtcg atcaatcctt ttttgaagtc gcattctgtt tggaaataac gacggatgat
    10141 ttcttgttta gaggcttctt ggacaacggt atcatccacg atcccaaatc ctacacgatt
    10201 cacacccatg tcagtaggag attgataaac agattcttta ccagtaattt tttcaataat
    10261 acgtttgatt acaggaaatg tctcaacatc ccgattatag ttcacagcta ctttattgta
    10321 ggcatcaaag tggaaggaat cgatcatatt gacatctttt agatcgactg tggctgcttc
    10381 ataagcaatg ttcagcggat gtttcaacgg aacattccat actgggaaag tttcgaactt
    10441 ggagtaacca gctgcatgtc ctttttggct ttcatgatac agttggttca aggaagtagc
    10501 gagctttcca cttcctgggc caggagctgt cactacaacg attggtttag ttgtttcaat
    10561 atactcattt tttccaaaac catcttctga gacgattttt tctacgttga ctggatagtc
    10621 ttcgatttct gagtgtttat agaccttgat gtttcgtctt tctagtttat tgataaagac
    10681 tttcgtggca ggctgtccac tatagcgagt gataacgaca ctgttgatta ataagccata
    10741 accacgtaat tcatcgatta accgcaagat atccatatca taagtaatcc cataatcacc
    10801 acggatctta ttacgttcaa tatctccagc atagacgcaa atcagtattt cagcttgatc
    10861 tttcaatttt tgcagcaatt tgattttcgc atcttcttca aatcctggaa gtacacgttt
    10921 cgcatgcttg tcgtcaacta gcttcccacc aaattctaaa tataatttgt catagtggtt
    10981 cactcgttcc aaaatatacg ctgactgctc ttcaatatat ttttctgaat caaaaccaat
    11041 ttttttcact aggttccctc cttaagtact aaagcatttt ttcatttttt tgaggattcg
    11101 tcaactggaa gagcgaaatt cctcaaaaaa acaaagaaaa tggtttaaac caacttgtct
    11161 agatagttat tcattggtat gatagttttt gataaggaag gtgctacatg aaaaaaagac
    11221 agaaaaagaa aaacgcatat aaacactata tccgttcgat ttttaccggt tatgaaagaa
    11281 tgcttgaaga tcccgaattg gaacaattga cgtttactta tctaaacgaa gaaacgcagc
    11341 taactcgtga tgagcatcag cgcattcatt tcacaacaag agatctgcct agtaaataaa
    11401 aaataagata aaggtcatcg gattcgattc tgtcctatca gatggaaaga ctagttgatc
    11461 gaaaaaaagg ctgtaccaaa ttttggtgca gcctgtttta tggagcattg cccgctcttt
    11521 tttataacaa ttttttacag aaaatggtac tattgaagta ttaataagtg aaaaacagat
    11581 gagtaagagg aggcaagtag tatgaaagag ccagatacaa atgcaaatta tgagccagac
    11641 gaactagagg agacgaatgc ggatcaggat acaggacaag aatcgtcttc tttttacgat
    11701 atcaaagaaa aagcaagcat gaatctttcc caattattag aagacttaca ggcttttgaa
    11761 aaagctgtcc gcgaagaaga tatccctgag atctaccgtt tatacaatgg ccgattgaat
    11821 gaagaattaa aaagaagctc aaatgaaaat cacgagatcg atcaattgct gatgcgtaag
    11881 atccatgatc gttttttaca ggaatttcct tttatggaac aagtagaaaa catctcgcca
    11941 acgatgagct attacaaaat cggcacttat taccatgatc ggcccacggt cggtattgat
    12001 gcaagtctgc cagaaatttt tgttttgcct aagatcgatg aagagtggga gaaatattcc
    12061 caaccggagt caacggacta tgacaaaaaa atcaatgagc tagacgcaaa ggtgatcact
    12121 gctcagacag aaattgaacg tttagatgaa caaataaaag aaatcaatcg acaaatgact
    12181 gatttgaacg acaataaagg attcttgaat cgtaaaaaaa tcgaggaaga aattcaagaa
    12241 ttagagaaga agaagcaagt actatctaat gaaaaattag gctggcttcc ttatattgag
    12301 acgcctgaaa caatccagca gcaaaaagaa gcattgaagc aagaagcaag agcagaccag
    12361 cttcgtgcag ccatcgtaga aaaagaacaa aggcaaatca gacgctattt cggtagcaaa
    12421 gagggattcg gtcaagcaat ccatgaattc ttgatgaatt atcttggcaa tgagaatcct
    12481 aataatcaat ctaatgaagg aggttccgag tatgaatgaa cacgatgaag cagaatggac
    12541 aaaaaatgaa gaacaaacag aagatcatga agaaacgaac acttcattgg aagaacaaac
    12601 aagtaatcct ctggatgaca cagaagaaat ccctatgcta gaggaaacaa aaatacacga
    12661 aaaagaaaaa gtaactccga cgaatacgaa tactgcagaa aacacccatg cttacgaaat
    12721 aactgaaaat cccgggtatt tagaaggaaa agagcaagat catcaagata tcgtcagttt
    12781 gattgaaaca gcggaagcag aattagcgga tttacgtatg agaaaagatt tgatcgaatc
    12841 agattttcca caattattag aatcatatga tcgttttata ttgaatgaag aaccaatctc
    12901 cacgatcgga aagacaagcc tgatcgaata cttcacgtat gaattactga aaccgttgaa
    12961 tgatattggt ctggaacggt caaattcagc ttatgacaca tggaaaacaa gacatttttc
    13021 gatcaattat acgttgaatg gacaaaacga attagtcttt tcctttgtat taccgaccat
    13081 cgatcaacga taccaagtgg aatcgatgag tctcctaaac gtatcaccag agacaatgga
    13141 aatcaatgtc caagatgacc gggtgctttc tttgatccga cactggtcag tggatcgagt
    13201 attctctgca gggcagatca cgatattcaa tcacaaattg aatcaattat tagcccatgc
    13261 aagaacactt ggttttaccg ttaatcagac attactagac aatacgaagc cacttcgttt
    13321 gaatcttcag agcgaatttg aattgacgaa tgaagtattg gatgatattt ttatcgtggc
    13381 aatgaaaaat ccatcctacg atatggaaaa gatcaacgaa actacttatc aagtacgatt
    13441 agataaagga cagtctttaa cgataacaac aaacgaaaaa gatcaaacag tcttgtcgat
    13501 ctcatctgga gactacccac gatctgtcat tgatttcttt atcaattacg aattcttggt
    13561 cccattaatg gtgagaaagt cctgattgga taagttggat taccagatgt cattcagata
    13621 attctgttcc aaaggacttg cggcagttat ccagaataat tgtcacaagt cttttctgta
    13681 tgtactaaat ggacgtgaat aacttgctga tgaaggaggg atttcattag gaatgtccac
    13741 aaataaaata gcacagctta gcttattgtc tgctgcttgt gtagcaggta ggatcgcttt
    13801 tcaatttatt ccgaatttcc agccaatgac tgctattttt ttatttatag tactttactt
    13861 aagcttaaaa gatgcgttaa ttgtcatgag tctttctatt gcgatcagca gtttttattt
    13921 tggtgttgga ccatgggtca tcggccaatg gatcagctat actgttgttc tgagtttgtt
    13981 ttcaatcgtc tgcttgagaa aaacagtgca aaggaatcta tggttaaagg gagtctgttt
    14041 ttttctggcg ggcatggttt acggaatagg tatgaccgtt tttgatacgc tgttatatcg
    14101 tttgcctcaa ccttggatct attaccttca aggggtgtcg tttgatttga tgcacagtat
    14161 aggcaatgtt gtgttctttc ttgtttttct gccagtcgtc aaacgttttt acaatcattc
    14221 aggaggaaaa aatgaaaaaa ataatttata gtttgcttgc aatgagtgtc agtatactca
    14281 ttttgacaag ttgcagtaca acctatacac aatcggcttc caaccaaaag gaggaagtaa
    14341 aaacatcgca aaaagcaaca atcacgttac aagaaaatgg tcaaaacttt tcggaaaaag
    14401 aagtgttctt caaaaaaggc gatgatttac tgagtatttt gaaacgaaat tttgaagtca
    14461 aagaagataa cggcttcatc acttcgcttg aagggcactc acaggatgag aaaaatcaac
    14521 tctattggat gtttactgtg gacgggaaaa gtgctactac tggtgccaaa gagatcaaat
    14581 tgaatgatgg acaatcggtc attttcaatt tgtctaaact ataagtttca taaaaaactg
    14641 ttaaagggcg aatattgcca taattcagtg agttcagttg atgaaagaag gaaaataaca
    14701 tggaaaattt taaaaaaagc ggaatgtttt ccgtaattgc tgctctaggg gctaatattc
    14761 tagttgctat cagcaaattt gtcggctatg caatcagtgg cagtgccgcc atgctaaacg
    14821 aaagcatcca cagtatcgtt gattgcagca atcagatttt gctgttattc ggtgataaac
    14881 aagccaataa aggacagagc gagttgcatc aatttggtga aggacgagca aaatactttt
    14941 tcagtacaat cgtcgcaatg atgcttttct tcggcggtgg ggcacttggg gtgatggaag
    15001 cttttgaaaa gttgacgcat ccatcccatg aagtgggtaa tccgatcatt gttatagcaa
    15061 tactgttatt tggtttggta atcgaaggaa gttcgttacg cgtggcaatg aaagaaatca
    15121 aagaattgaa tactgaaaaa ctttccacga tgcgcttttt gcgcgaaagt cgacacagtg
    15181 aaatactgat tatttttacg gaagacttgt gtgctgtaat cggtttggtc ttggctttag
    15241 caggaacaat attgacttat gcaaccggga ttgctgcatt tgatgcgatc agcggattgc
    15301 tgatcggttt cttgctgatg ggagccgcca ttttcctagc aaaagaattt tatagtctga
    15361 tcatcggtga aagcgtgaca gcaagcgatt tatcaaaaat caagttagct tttgaacgtc
    15421 ctgagatcag tcggctgatc gatataaaaa cagttcattt aagtccaacg gagattttag
    15481 ttgcagcaaa agcagatatc gttggtaaca aagagaatga agcttactcg gtcatcaatg
    15541 atattgaaaa aaatatgcgt cagtctcttc ctgacaagaa gatgtatata tacattgaaa
    15601 cagataaata tgacccaaat tattctcgta aataaaacgt ttattcatga attgaagcaa
    15661 aaatgagaaa aatataatct tgtttttaaa taaaacggct acaatttagc gaatttatgt
    15721 tacaatgagt ccgctgttta tttgttgtaa ttaaaggaga tattttaatg aacaaaaaga
    15781 aaagtgcgcc atggcttcaa gctttgcatg cagtgatgcc actttgtata agctatatac
    15841 cagtaggatt agcttgcgga gtattgttgc aaaaagttgg atttgatcct ctcttatcag
    15901 gactgttatc gattctggtc ttttccggtg gcgcgcagtt tttagttgca tctatgctta
    15961 cgacgcaagc atcatttgca acgacattat tgatggtttt ctttttagaa ttacgctata
    16021 cattattagg agcaagtctt gccggtttta tgaaaaaaga aaagcggacg tttttggctg
    16081 tcttttctca atcactgaat gatgaaaact atgcggtgaa ctacttaaag ttttcaactg
    16141 acccttcctg gaataaaaga aaggctttat atgtcaattg gttctcaatg actgcatggg
    16201 ccggtagcaa tatgatcggt aattttttcg gctcggtgat tcgagtagat gctgaccttg
    16261 tccattttgc tttgacggcc atgttcattt tcatgtttat catgcagatg aaaagcgcac
    16321 tactgatctt tacaggttta ttctcaggcg tattaggggt cgtattcatg gtattattcc
    16381 aaaatacttt cggattgatt gcagcaacag tcattgcttc atttgccgga tttatgctgg
    16441 agaaggcatt caaaaaagaa aaagctaaga aactaagaga ccgcggtaaa gatgtcaatg
    16501 agccgctctt caacttcccg gaacaggagg ccaatcacca tgactaaact atatttgcta
    16561 cttttagttg tttgtctgtt catcgtggca tatatcccgc gcttgttccc gatgctttat
    16621 tttactcatc gaaaagtgcc atcctggttc agtgactgga tgaaatatgt accggtggca
    16681 ttatttgcgg cgttagcttt taaagatgtt ttcattactc atgaacatct ggatattgct
    16741 tggaatatca aaatagctgc aatgattcta gtagcaggcg tggcttacaa aacacgttcg
    16801 atggcgttgt cagttttgac aggacttgcg tctgtctttt tgctgtctat gctttaaact
    16861 gttttatttt attaaaaaca gagattgcga cataagttgt tcaaactgat ctatccgaac
    16921 tgcatttgca acagtcaatt ctggatgcaa gtttattcgt agggataaaa aagattagtg
    16981 ttggcttatg atgcaagctc ttttttattt taggaattag agagggattt gtccttctat
    17041 gattttttgc tataataggg aagatgttta ttttatgaaa gaatagttga gggaatttaa
    17101 atgaataaaa aattgatgca aggaacattt tggctaacct ttgctaatct tctatgtaaa
    17161 gttttagggg tagtctattt gattccctgg ctaagtatga tggggaacaa tcaagatggt
    17221 atgcttgcta cgacattgta taatgttggc tatcttcctt atggattgtt cctgatgctt
    17281 ggtacagtcg gatttccaaa tgcgattgca aaaaaagtag ctgtagccac aaaagaagga
    17341 gataacgctg cttgtcggct gatttttaga agtacgatca atatcatgtt tgtcatcggt
    17401 atcgcctctg ctgcactgat gtatttattt gctcctttac tagccggaat cagtccgatt
    17461 gctaacgtta ataatgggat actagctatc agaagtttat gcccatcttt gattgctatc
    17521 ccaattctta gtgcaatgag aggatatttc caaggaaaaa atgatctgcg gccttatgga
    17581 acttctttga ttatcgaaca ggctgtgcga gtgatcgtta tcttggctgg tacttattac
    17641 ttgcgcgtat tgactgacgg aaccatatta gaagctgtat tgatcagtac agtcgcttct
    17701 ttcttcggtg ggttagctgc gattatccat atgtatatcg tcggacgcag aaaagacttc
    17761 ttcgaactta aagatttttt gatttccagc cgttatttcg aaagagaaaa ccgatctgcc
    17821 tctgtctcta tcattcggga aacactaccg tttatttttg tcggctcagt cattactatc
    17881 gttcaaatga tcgaccaagt aacgatgaaa ccactgcttc actttttccg tccagagatc
    17941 gcagatcagc aactggaatt cttattcagc cgtgcttctg tcaatccaaa taaattgaca
    18001 ttgatcctga tctccatggt aggaacagta gctataagca gcttgccaat attaagcacg
    18061 atgaagaaaa atgatcggat acaaatcgaa aaaacagtag gagatagttt ttcgattgcg
    18121 ttattgattc ttcttccttc attgactgga atgtctttat tagctggacc actatacaca
    18181 ttgttttttg gctatgatcc tgaaagtgtc ggatatttcc aaatggcttt gctagcttct
    18241 ttgtttttct ctttattcac gatcctatct acgatgcttc aatctttgaa tcaccatcgt
    18301 tttgcgatcc gattaactgt agaagcaatt atcctgaaag tcatcttcca agtaatcgga
    18361 ttaggattag ttggcggata cgggatgagc ttatcaaatg gcttagcatt cggtattgtc
    18421 tttgttcgcg gctatcactt tatgtgcaaa gaataccgaa tagcaccttt agcaaagatc
    18481 agcaattttt tcttaaaaac tttccgctcc accctgatta tgcttgcagt atgttttgcc
    18541 gttttctttt tgctgaatca gcgattgtca atggaatcaa aaagctatgc aatgatttat
    18601 tgtgtggctg taggaagtat tggcggctta gtatttttat tttctcaatt cggaaaaaat
    18661 gggtttcgaa tgttgaaaaa tgttaaacat catagcagaa gcaaagaata ggttaactaa
    18721 tcgttttttg ctgtcacttg aaaaacggca actcgtatga ttacgcttgt cgtttttcta
    18781 ttttccaatt ttagtttcat atctaatctt acttatgata tagttataag gtctggaaaa
    18841 attctttgaa acgaggaaat taaacacatg aaacttgcag tagttacaga tagttcggca
    18901 tatctgccgg aacgtatcaa gaaccatccc gacttattcg ttattccaat ccctttgatt
    18961 atggatggga aaatttataa cgaaggaatc gatatcgaag cggatgaata ttatggactt
    19021 ttaaaaaaca gtaaagattt tcctactact tcacaacctg tcgtagggga agttttgggt
    19081 ttatatgagg aattgaaaga gaaagggtat gacacgattt taagtatcca tctttcttca
    19141 gggatttctg gctttgtcaa cacattattt gcgatgaaag atgacatcag cggagtaacg
    19201 gtcattcctt atgactctaa gatcactagt atgccgatgg gacacatggt agaagctgcc
    19261 ttagacttaa atgatgaagg tcagtccctt gatgaaatac ttgcacatat cgatcgaatc
    19321 cgagataata cctacgctta tctgattgta gatgatttga acaatttagt acgaggagga
    19381 cgtttgacaa atggtgcagc gctgattggc agcttattaa aaatcaaacc gatcctgaca
    19441 ttttctgaag ggaaaattgt tttattcgaa aaaatccgtt caagtaaaaa agcatttgct
    19501 cgagctgaag aaattattgg tagaagaaat aacgaaatac aaccgccagt caaactttac
    19561 gtgatacatg caaataattt agaagtagcg attgcggaga aagagaaatt gcagaaaaaa
    19621 tatccaaatg cagaaatcga aattggtcat ttcggaccag tcattggtac acatttaggt
    19681 gaaaaagcca tcggcattgc catttcagcg caataattcc ttttattcaa aaaacatacc
    19741 aaaaatattc caacatcatc ttggactttc tacatgttac taatgagcgt gtaaaa
//
LOCUS       DACBZK010000050        19185 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.052, whole genome shotgun sequence.
ACCESSION   DACBZK010000050 DACBZK010000000
VERSION     DACBZK010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19185
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.052"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(37..1188)
                     /locus_tag="IVD66_001888"
     CDS             complement(37..1188)
                     /locus_tag="IVD66_001888"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAP6146093.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1201..1638)
                     /locus_tag="IVD66_001889"
     CDS             complement(1201..1638)
                     /locus_tag="IVD66_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP6146094.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1653..3419)
                     /locus_tag="IVD66_001890"
     CDS             complement(1653..3419)
                     /locus_tag="IVD66_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HAP6146095.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3683..4360
                     /locus_tag="IVD66_001891"
     CDS             3683..4360
                     /locus_tag="IVD66_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6146096.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4363..5490
                     /locus_tag="IVD66_001892"
     CDS             4363..5490
                     /locus_tag="IVD66_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6146097.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5690..6130)
                     /locus_tag="IVD66_001893"
     CDS             complement(5690..6130)
                     /locus_tag="IVD66_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP6146098.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6141..8174)
                     /locus_tag="IVD66_001894"
     CDS             complement(6141..8174)
                     /locus_tag="IVD66_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP6146099.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGLFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8176..9879)
                     /locus_tag="IVD66_001895"
     CDS             complement(8176..9879)
                     /locus_tag="IVD66_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6146100.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(9973..10923)
                     /gene="manA"
                     /locus_tag="IVD66_001896"
     CDS             complement(9973..10923)
                     /gene="manA"
                     /locus_tag="IVD66_001896"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HAP6146101.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10962..11987)
                     /locus_tag="IVD66_001897"
     CDS             complement(10962..11987)
                     /locus_tag="IVD66_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAP6146102.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(12196..13065)
                     /locus_tag="IVD66_001898"
     CDS             complement(12196..13065)
                     /locus_tag="IVD66_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HAP6146103.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13524..15416)
                     /locus_tag="IVD66_001899"
     CDS             complement(13524..15416)
                     /locus_tag="IVD66_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6146104.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15413..17140)
                     /locus_tag="IVD66_001900"
     CDS             complement(15413..17140)
                     /locus_tag="IVD66_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6146105.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17156..17806)
                     /locus_tag="IVD66_001901"
     CDS             complement(17156..17806)
                     /locus_tag="IVD66_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6146106.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18010..18306
                     /locus_tag="IVD66_001902"
     CDS             18010..18306
                     /locus_tag="IVD66_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP6146107.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            18498..19118
                     /locus_tag="IVD66_001903"
     CDS             18498..19118
                     /locus_tag="IVD66_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HAP6146108.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
BASE COUNT         5455 a         3954 c         3381 g         6395 t
ORIGIN      
        1 aaaatttcgt cacattcccc tttttcgtat cctattttaa gcgacttgct tggcataacg
       61 gttcacgttt tgcttgatat tcccgattgt tttcggatca ttgattcctg tgacttcttg
      121 aatcaattgt tccaagtttt catggatctt catttcatgc aattgacggc tttgttcatc
      181 ttcaggatca tagtaattaa aaataatccc cattgttgcc gtcaaatgtg ggcaagtcaa
      241 gttatgttct tgtagttctc tcactggacg tgtaaatctt tcttgataac ctaacttacg
      301 taatggtgtc cgagcgacac gtgtgatcgc atcagagata tttttgtttt ggaagcgatg
      361 aatgattttt tcaatatacg catgatgctg ctctgcatca aacccccatt tggcaatcag
      421 caaacttcct gtttcctgca aaactgattt taattgtgcc acaactaacg catcttgcat
      481 tgcttcatca atggtctggt aacctaacaa ggcacctgta taagcgacag tcgcatgacc
      541 agtattgaca ctaaatagtt tgcgttcgat atatggttct agatcatcta catataaaac
      601 cccttttaat tggatttttt tattttttct ttggctatcg tcaatgaccc attctttgaa
      661 aggttccact tggacgaata aaggatcttc atggtgttgt aatgggacga ttcgatcgac
      721 tgctgcattt ggaaagccga tatatttgtc agtaaatgat gtttccggaa gatatttata
      781 cacttctttt tctagaaatg ctgaaccgcc aatcatattt tcacaggcaa tgatatctaa
      841 agatgttgtg cttccttcct tttctctttc ttggatacct tttgcaatca actcagcaat
      901 aaaaggtaag atattcgggc caatggcggt agtaactaaa tctgcttcag cgatttcttg
      961 gattactttt tctggatttg tttgattgtt gattcctttg acatttttta cagtgatttt
     1021 ttcttttgat tcatctgcta attcgatttc gtattctttt ctttcattta aagcatcaat
     1081 gatcgtgtga ttcacatcta cgaaagtaat ctcaaatcca ttagctgcca aaacctctcc
     1141 aataaatcct cgaccgatat ttcctgcacc aaaatgtact gctctcattt ttctctctcc
     1201 ttaagcaatt gctagatttt ccgttacttc ttctttgctg agcgcgtctg ctagctggac
     1261 aacattgtcc atatcactgc aataaagtgc gatttgctgt acaagttgca aatgctcatc
     1321 tccgactcct gcaataccga acaaaacagt cgcaatcttt tcttcttctt cggtaccaaa
     1381 atctacacca tctggtactt gaacgacaca gatgccggat tttttcacat atttttttgc
     1441 ttcatctgtt ccatgaggaa tcgcgataaa attccccata taaacagata acattttgtc
     1501 tctatctacc atggcatcga tatattcctc atcaacgcac cctgcttcta caagcatctg
     1561 accgcaatag cggatcgctt cttctttggt tttaaaagat cgattgagct cgatcatgtc
     1621 gaatggcaaa ctttgcatgc tgttttcctc ccttaagctg tctgtttcaa atattgtgca
     1681 atcgattcgt atttttgcgg attgaccatg ctgttgactg ataaatgaat ggattgaggt
     1741 gcagccatct gtactttttc cgctaaactt tctttggcta cgatcagtga atcaggttca
     1801 tcttttaaat cttggatatt gacttttctt aacgggatag ttaaatggtt cttgtctaat
     1861 atatctttga gcacggtcat ccccattgtt gctgatccgg aacgatcatc gtggacaagt
     1921 agaatctctt tgatttgttt gatgtttgct gaaagaaact cttctgctgg ctcattctca
     1981 atttcagaaa ctgatgtttt ctgcttgctg cttaattctt gaatgatttc atcatatcga
     2041 ggtgaattca aaaagttttc tactgagaca aaacgcgcgc tcggtgcttt ttgttttgct
     2101 ctttcttgta gttcgacctg agtaacgatc aatgtattcg agtcatctgt cagttggctg
     2161 attgcttgat tggtcaccgt ttgaggcaag tctgcttcct gtactttttt tctcaagatc
     2221 gaagcgccca tcgcacttga tcccattcct gcatcacaag caaaaatgat tttttgtacg
     2281 ccagagaatg tagctccttg aggaatacct tgggcacctt tggaagcttg cttagctgcc
     2341 tttgtctctt gaacagattt ttcgaagtct tcatttgtat ctttcgcatc cgctttcaaa
     2401 attactgcag aaataccaaa cgaaacagct gcggcaacaa tcacgcccaa aataacagga
     2461 aggtaagaat tgaacggtgt catcgctaga atcgcaatga tcgaccctgg agaagctggc
     2521 gctcttagtc cagcatccat caattggaaa atgaaacttc ctgacattcc tccgcctata
     2581 actgataaga ataataacgg tttcatcata acgtaaggaa aatagatttc atggatcccg
     2641 cctaaaaagt gaatgatcat ggctcctggt gctgaagatt ttgctgctcc tttgccaaac
     2701 aaagtaaaag caagtaatac gccaagtcct ggaccaggat ttgcttcaag caagaataga
     2761 atagattttc cagcctctgc tacttgttca gttcccaatg gtgtcaaaat cccatgattg
     2821 attgcattat tcaaaaataa gatttttgct ggttcaataa aaatacttgt caatggaatc
     2881 aaatgggcag ataaaatgat ctctacacct tttgccattg cttgagtcaa tgcatcgaca
     2941 actggaccaa tcgcagaaaa acctaataac gctaatccaa aaccgataag acctgctgaa
     3001 aaattattga ctagcatttc aaaaccggat ttgatccgtt tttggaatag ctgatcaaat
     3061 ttcttgatgg catatccacc aagaggtccc atgatcatcg cgcctagcat cattggaata
     3121 tctgttccga caatcacacc catcgttgca attgccccaa caactgatcc gcggtcacca
     3181 gcaattactt ttccgccagt ataaccgatc aataaaggaa tcagataagt tagcattggg
     3241 cttaccatgg tagccaaagc ctcatttggt aaataaccat ctgggataaa tagagccgtt
     3301 aatacacccc aggcaatcag tgctccaata tttggcatga ccatgcttga taaagtactg
     3361 cctaattttt gtaccctcgc ttttagcgaa atgttgtttt tgggaatcgt ccgttccatt
     3421 ttgtctctcc ctctctcctt ttgatactct aattgtatcc gcttactaaa aagagaaata
     3481 gtcgtacttt ggcacgaaac tttgtgccaa aggtttgagt atgtcagcaa aataaaaaga
     3541 tttcggtatc agaaaacttc aattttaaat aaaactgtta ttttaatttt tttataatat
     3601 gcaaacaata acttttgtta gcatttaatt tagatgtttt ccattctatt atgttattaa
     3661 attttatatt ggaggcctat ctatgacatt actgatcaaa aacatgaaca tgaaacgtgg
     3721 taaaaaacgt gtgattcgac aattgaatct tttagtagaa tcaggagaag tagctgcttt
     3781 gattgccccg aacggatttg gcaaaacaac tttgctgaat ggcattgccc aactgctgcc
     3841 aacaacttat gatcaattgt cccttcacaa catctctcct actgcttata cagattatcg
     3901 ccggtctttc ttttttctag aatcaacgaa tcagttatcc gactatctat cggctgttga
     3961 ttatttgact ttgatcaaat actattggca gagcaaagta gaatgccaaa ctgttttcca
     4021 acgattgaag atgactgagt accttacttt gccgattgga aaaatgtctc taggaatgaa
     4081 acaacatgtc ttgcttgctg cttacttgat cagtgattca tctgtcatgt tattcgatga
     4141 accgttgaac ggattagacc caggaagtat tgatatcttg aatagcctca tcagacaatg
     4201 gcagaaagag gggaagacga ttcttctttc ttcccacgct atcgcgaata tccaatcgat
     4261 ttgttctaaa gcatgttttc taaaaaatgg agaaatcgtc acagaatcct caaatatgga
     4321 agagatttta gctatttatc gtaaattata tgaggtgtaa ctatgtcttt acttacattt
     4381 gaacgcaatc tcttactaaa aaacaaagta aactttttat ttcctctatt gttggtcgtg
     4441 ctctttgcat tcccactttt ttttgatcat aaacttgctt atacagaatt cgatgaactg
     4501 aatcataact atgaagagat gcaacgtttg attgaaacgt tgaaagaaga tgagaatgag
     4561 aaagaatttg tggaaagttt agagaaaagc aacaaactga tcgaagcaat cttacatgca
     4621 aaaaacacag ggaatgtcca gcaaatggtc gaagcaactt atcattatga aaaagatata
     4681 ctggatcgac tgatttctgg tcaaagacaa ggaattccaa tcattgaaca acaaaaacgt
     4741 gtcgagttgc tccgttatat gaaagaacat cagatccaaa gatattctat ttttgacttg
     4801 ccagcgcatc tccctttagc aaattactac gaaaatattt tttcaggaat gatttctagt
     4861 tttttgattt tatgtataac cgccttgttt ctttcttcca tcatctctta tgaaaaaaga
     4921 aagcaggtaa tctctctagt caatctatta ccggatagta tggtaaagaa acatagcatc
     4981 cgttttacca tttattatgg tgcagctatg ctaagtctcg tgatgccatt tttgatcgtc
     5041 tctatactag taataatcaa aaatggtttg ggagacttcc gttatcctgt aggaacgatc
     5101 attggtcagg agatacgaat ccttccgatg tatgagtatc ttttccagag ctttctgttc
     5161 ctgttgttgt gggtgctctt tttaagtaca atcagttttc ttctatctgc tttatttgaa
     5221 cattctctag tcaatctttt aggtacactt ctttgtcttt tcttagcaga gtatcgcttg
     5281 ttttcttcga ttggatggat agaatcaatc agtcattact tgccaacttc ttatgttgat
     5341 tttcaaaatg tgatcatagg aggagatatt ttctcgccac tagcttcaga acaggttact
     5401 ttcatgaatg gtatcttgac acttggtata tggagtatcg ttttattatt cataggtatg
     5461 ggcactatct atataaaaaa gagctattaa aacacaaaaa taataggggc ggtgacaaaa
     5521 accttgtcac cgtcccctat ttcaaataaa cggttttcta gaataaatag ttttcaaaag
     5581 cttgcatccg cagtaataag aacctcccaa caaaaatagc tcctcttatt tttatcttgg
     5641 ttgaagttat tacttgatgc aaggcagctt tttttactgt gaacattggt tatatatgtc
     5701 catgttcaaa aatcatttgg acttcttcaa tggttttcgc atcactgagc gccattactt
     5761 ggtcgatgtc tgaacagaaa aaggctaaat cttggagcac cgctaactga tgttcttttt
     5821 ttaaagccac tacaaataag agtgtcgcga tttttggttc ctcttttgtt ccaaagtcca
     5881 caccatcagg cacttggact aaatagattc cttcttctac tacttcttca tctttgtcag
     5941 tcccatgtgg caaggctacg aaattcccga tatagacact cgctttttct tgtctttcga
     6001 tcattgattg gatatatgcc ggtttgattc ccccttgttg ggtcatccac tggccgatct
     6061 cggtcaacgc ttctttccaa ttttgatagg attgatcgag caatattttt tctgctggta
     6121 gctgtatcat cttttcacct tcatttcttt atttcttcaa tcaggatttt cgctaacaac
     6181 tgataaacga tttctttatt tcctgagcgg aagatctcgg tgttcaagtc attcatgatg
     6241 attgctccac tgatctttcc taaaagaatc ccgtcttttt cttggattgg cgaaggcgcc
     6301 agcataacta acatacggga caaatcgact ggctgtctat ccatcccttc aatggtcaac
     6361 ggatgtttca aattgaaaat acaaaagatc ggtttagaaa tcaatgagct ggatgtatgg
     6421 aataacccca tatttgtatg aggaataccg ataggtgctt gttcatatcg cttaagcagc
     6481 cggcgatgaa ccacctcttc atccgttact agtccttcag gaaaataagg aaataagctg
     6541 cgaatcgttt cggaaatcgt ctcaggatta tccagttctt ggataaaaaa aagaccgagt
     6601 aattgattga tttgatccat gaaatgcatt gtttcctcat aagtatcttc tatcatccac
     6661 tcgttattgc tgttatacgt aattttttgc ctttttttct tctcaatatg cgaaaaagct
     6721 tcttttagct gcttgacttc atcttctagc agtagcgggg agactaaaat atattttcca
     6781 ccgtatcctg gtaaaataga tgtagaaata acaacatcat attcttcttg taaatcgatt
     6841 ttttttaaat cagcaatccg atagaaatga atttgttgga tgaagggaaa ataccttttc
     6901 aatcgtagtt ccaacatgct agtagaagct aatccacttg gcgaaaatcc tgcaatactg
     6961 atattgcttt ctttcggact tcgttccaat gaattcgcaa aatgaaggac catataagcg
     7021 atctcttctt cggataattt tttttcttga aaaatccgct ctactgcttt acggattgca
     7081 ttcgcaactt cctcgtattg aaccatgatt ttttctaaaa tcggattggt cagtgtctct
     7141 tcttgtaaaa cggctcttga aaacacacca gataaatgag tcaacagcat tttgtacaaa
     7201 gtttcatctt cataaaaatg gacattcgtc tcttcactta cttcttgaat cagttgtttt
     7261 actaaataag caagctgtgt atcgaacgtc tcttcaaaga aattctgatc aaatgagttc
     7321 gtgaagtcat ttaataatcc tgcaaaaaag acgatctcat ttactggata aagttgtttt
     7381 gtctcagaag cgatccgtga aaacaatcgt ttagctgtct gtagtaattc tttgtttgcc
     7441 agactattat atgtctcatt tgtcagtaaa tgatttttag tcacacgctc catcgtcaat
     7501 gtcagcatca aaaccaaatg ttcaagcttt ctatcactta gattggtctt tttttggatc
     7561 aattcttccc cgattacttt gcgtgcaaga gatagatgtt gcggatcaac gaatcgaaaa
     7621 aaataattca gtgatgcatc gaaagaaata ctatgaaaaa gttcatattc attgatttct
     7681 aattctaata cattcgctgt cagaagccgg cggtattttt ccggtccttc gatctcgtat
     7741 ccctggttcc gaatgatttc caaaggcagt tggcgaatac tttcttccaa ctgtttgata
     7801 tctgcataaa aagtggtatt actgatgcga tatgattcca tgaaatgagc aagactcaac
     7861 ggctctgtcg tcagtaacaa ctcggctaaa atcgcgtgtt gtcgtttagc agtggataag
     7921 tcattacttt tcccatctgt attttctttt aattgctcta atacttcttc tgatgcctca
     7981 atgacaaatg agcctctagc tgcttttttc aaagaagcat ttaccgattt caatgagact
     8041 tcaagattat ctaattcgcg gtaaatagtc cgtttactga ccttcaataa attcatcatt
     8101 ttttggatag atacaggtga cgggctactg agaaattctg ctaataattg tttttctctg
     8161 ggcgataaat acatcttata tttctccctt cacgagtttt tcgtattcat tcgtagctac
     8221 ccaatgttca actagaacta gccgagggat cttttcttct agctgttcag ttacagctag
     8281 ttctctttgt gcgatataaa tcgtttcttc ttggattttg attttttcta ttgattcttt
     8341 tgagataaca aactgttttt tcgctttttt tgctaattga cttaaaatcg tcatgcccat
     8401 agtttgtgag ccgcgtctgt tgtttttata caaaaataca atattagcag gcgacttttt
     8461 ttgttctgtg atatctgcta tctctttttt ttcttcccgc tttggaaatt ggatcgcttc
     8521 ttttattcgt gacagcaaga tatctgtttc caaaaagtga tccagtacat agatttgact
     8581 ttgaggtact ttttctcttg caagacccgc tagttcatgt tgcacgataa ccagctgatt
     8641 tacttggtta ttcaattcat agatagagct gtatccgaca gaaagatcga ttttttctgc
     8701 tgctaatttc tttttcagca gggcggctcc catagcactt gatcccatac ctgagtcgca
     8761 agcaaaaatg acggaatgaa tgatagatgg ttccaagatt tctccccttt ctttgaccgt
     8821 tttgttctct ttttctttat ttggtaattt caatagtatc gctgcacaaa tgaaggtcac
     8881 aaatgtactg attgctatcc ctatacttac cccagctagt tgtggataag gcgcattggc
     8941 aaaaatcacg agtagtgacc caggcgatac aggtgcagct aatcccgtat ctaaccattg
     9001 aaatatcaac gtgccgcttg ccccaccagc cattacagct aaaaatagat acggtcgcag
     9061 caagacaaat ggaaaataga tttcgtgaat cccgccaatc gcatggatca tcaatgctcc
     9121 actcgcattt actttttcct gtttttctgc aaaacaaagg atagaaagta agatccctaa
     9181 accaggtcca ggatttgcct ccatcaaaaa taaggaagag tacccgactg tttgtgagaa
     9241 ttcgattcct aaaggtgtca atacaccatg attgattgca ttattgaaaa atagtacttt
     9301 tagaggttct aagatcagac tgacaagtgg taacagattc attgtgacta gccaagacac
     9361 aacggaggcg agcaacaagt gaacactatt taaaactggt tcaataaaaa cgattccaat
     9421 tatacaaata acgctaccag tcagtcctac tagtaggttg ctgacaagca tttcatatcc
     9481 agccttgaat ttcacgtgga atctagaaac aaattgttca tatacgatgc cggcaagcgg
     9541 cccgataatc atcgctccta cgatttgtgg agcattggaa cgagcgatca accctaaaga
     9601 agcaattgca ccggcgactg cccctttttg tccccctacc gatttcccgc ctgaataact
     9661 gatcaagatg ggtaaaagca gctggatcat ccaatggcat acctcttcta atgtggtgtg
     9721 caaatcgcca gacacacctt ttgttgctaa tgacaagatt ccccaagcga taaacagact
     9781 tagatttggc atgatcattt catttaagtg atgtccagct tttctcagtt gtttcataga
     9841 cacgcgactg ctgttgtttg ctttccattt gtattccatc tttttcacca tacttctatt
     9901 tattgatgga cggattttat gtagaaaaag cagcaaacga aaaaccgtct gctgctttca
     9961 gctatctggg aactatttgc ctggttcagt cgcaatgatt gctagttcac cttggaccgc
    10021 ccactcagaa acgccatttg gaataataca gcttgttcct ttttctaatg gatatgtttt
    10081 tccgtcaacg acaaggtctc ctgctccttc gattaccgtc atcaatgtat aaggggcttg
    10141 ttttttgaaa gatgtgattc ctttaatatc ccactcatat acattgaaaa actcagtttc
    10201 taaataagtg acgatcgatg aattcccttt tcggacttct ttgatttgta attctggtgt
    10261 tttcgcaggg acagttgtta catcgatcga ttgttggata tgcagctctc ttgtttgtcc
    10321 ttgcgcatct tttctgtcgt agtcatacac gcggtaagtc gtgtcagaac tttgctgtgt
    10381 ttctaaaatc atgattcctt taccaatagc atggatcgtt ccgcttggta cataaaagaa
    10441 atcacctttt ttaactggta ctttcttcaa aaggtcatcc cagcgcccat ctttgatcat
    10501 ctcagctagt tcttctcttg tctttgcatg atgaccatag atgatttctg caccaggttc
    10561 agcatcgatg atataccagc attcagtttt tcctaattca ccttcatgtt tcatcccata
    10621 ggcatcatct ggatgtactt gtacagatag atcatcttct gcgtctaaga tcttgatcaa
    10681 taatggaaac actggttctg aaggatggcc aaacaattcc ttgtgttctg accatagttc
    10741 atctaatctt ttccctttga attcgccatt ttctactaca ctgacaccat gaggatgcgc
    10801 actgatcgcc caatcttctc cgattttatc gttagggata tcaaaaccaa agactgaacg
    10861 taaacgactt cctccccaaa ttttttcttg aaaaactggt tttaaaaaca taggttcctg
    10921 cataattcaa actcctctca tttttcatag ctattatagc attatttcgg taataccgct
    10981 ttctctttca aaaagttttc aacaatttca tctcgacata tgagatactc cgcacgatga
    11041 tcgacaggat gtacgcgatt tgacaaaaat atcaacgctt cttgtgtttt tatatcaatc
    11101 aagaaaaacg tacctgtata accagtatga aaaagaatcg catgaccgtc ttctacatcc
    11161 ttttttaagt cccatcctaa agaacgatag ccattttttt tcggtgtttg atcttgcagt
    11221 aaagaatcaa tcgtctcttc ttctaaaaaa cgaccattac ggatttttcc cttgttcaaa
    11281 tacatttgga caaaagtaat gctgtctttc aaatcaataa agagacccgc gttacctgca
    11341 tgttcagcca aaactcttgc tttcggatca tgagtttgtc cacgcaaaac ctcacccgaa
    11401 ggcagttgtt ctgtgggaac gatttttttg gaaggaaaag gaagaaataa gctgttcatc
    11461 attcctaatg gttccaatac ttgttcttga aagatttcca ctgcagtttc ttggtaaatt
    11521 tcctctagca tcaacccaag aagaatcgta ccggcatctg tatattttac ttcttttcct
    11581 agttgctcac ctggttctag cttcaaataa gcggcgatca attcttcctg agatagctta
    11641 tctctgtttg gtatccatgt tttgatatca gaagtatgtg tcagtaaatg acgcaaagtg
    11701 attgtctgat tttcaaattc aggaagatat ttatgaagcg gttgatcgag ttctatcttt
    11761 ccatcttcta atagacgtaa aactaatgaa gtggttgcaa cgactttcgt cagtgaggct
    11821 gcatcaaaca acagatcttc tgtcatcagc tgcttttcag gaacgacttg ggcaaagccg
    11881 gctgtaaatg tttctacttg attttctttt atgaaggcga ctgctacacc tggataaaat
    11941 ccttcttcca tctttttcaa aataagctgt ttcgtgtgtg gatacatctt tttctcctgc
    12001 ttttctatca gattcttaca gtccaagctt aaagcttaat ctatgaggaa tcaacctttt
    12061 ttacacaaaa aaactgcgcg aaaaaccgcg cagtttcccc cggtatacta ttttctcttt
    12121 ctatctctag aataagcgat agtatgaccg ttcataaaat gacgagacat gcgacaatcg
    12181 ttaagaaaga aaaagttaag cgtcgcatcg aatgtcagtt ttattctttt cttttggctc
    12241 actgacgaac caccattcga ttcctatagc atcatagatt gtgagtactg tgtgcttttt
    12301 gtctaagaag aaatcaactg atagttgctg caagtgagca atcagtcctt ccatgctttc
    12361 agtatcgatc atgaatttca gaaaatcaag tccaatcact tcatctgtag gcaaatcaat
    12421 tgcgcctccg ctagcttctg tcaaaccaac atggaaatct ccttcattca atacatggat
    12481 gccctcttct tcattatgta ccttcaaacc aagtacatga ttaagaaatt ggcgttcttt
    12541 tgttaagtta gtaacattta aatggatttt ttcaaaataa gaacctgttg atagtttact
    12601 gaatttttct tcagattttc ttaataatgc ttcttgatcc attgtttctg gaatttctct
    12661 ttggtcgttc ttattctctt catggtaaat ttccaattca ttctcttctg ggtctacgag
    12721 caaaatcccc atacgtccat gatcttctaa agcttctttg attggataat tcattttacg
    12781 gatacgacaa aggatatctg ccatttcttc tgtgctaggg ataatcaatg aaaaacggtt
    12841 cagctttttg atcaccccca tgtgatcatt cgctctagga ctttcttcca gcagcaacat
    12901 ttcacttcca gcttcttctg ttcctaaaat ggctaattcg ttttcttctc ttttcaaatc
    12961 aaagccaaca acgttcttgt aaaaatcaat cattttatct cggtctttca cccgaatggc
    13021 tacacttttt aaataggtgg cagcccccaa ttgaaaatct ttcatatttc ttgctcccct
    13081 ctacgtcaag ctttatttta acgatggatt cttcttcttt caagcaataa ctttgatttt
    13141 gttaaaaata atgtgagaaa attcgcattt tgcttgtttt ttgtaaatta atgagtaaaa
    13201 actcttataa aaagaggttg tgaaaaagct gttctgcatc aagtaataag aacagccaaa
    13261 caaaaatagc tcctcctatt tttcgtttgg ttgggcttat taccgcagat gcaagctttt
    13321 gaacaccgtt taaggaagag gttgtaaaat cagcggtttg acctgagtat tagagataca
    13381 aaacggaaaa atagcttctc atattttgcc gttttttgag ctaataccga aggacagctg
    13441 attgaacacc gtttattcgg aaaaagggac tgtgacacga cttttgtcac agcccctaaa
    13501 aaaaataata aatttgtact attctatgaa gcttcttctt cagaaaactg actgttataa
    13561 agatctgcat agaatccgtc tttttccatc aatgtatcgt ggtttcctgt ttctacgatc
    13621 gaaccatgat tcatcacaat aatgttgtct gcatcgcgta ttgtagacaa gcggtgagca
    13681 acaacgaaac ttgtccggtt ttccaatagg cggttcatcg ctttttgaat cagtatttct
    13741 gttcgtgtat ctacactaga tgttgcttca tcaaggatca ggacatctgg atttgctaag
    13801 aatgcccgcg caattgtgat tagctgacgc tgcccttgcg aaatattgct tgcatcctcg
    13861 tttaatacag tgttatatcc ttctggcaat ttacgaacaa aatcgtctac gtgagcagct
    13921 ttagcagcct caatgatttg ttcgtctgtt gcatcgtcgt tcccatattt gatattgtca
    13981 tagatacttc ctgtaaacag ccaagtatct tgcagtacca ttgaaaactg tgcgcgcaat
    14041 tcatcacgtg aaagatcacg ggtatctaca ccatcgtaac gaatactacc tccagaaaca
    14101 tcgtagaacc gttcaagaag gttgatcagt gtcgtcttcc ctgcaccagt cggacctaca
    14161 atagcgacca tctcaccagg tttgacatcc aagttaaaat cagtcattag caagttatct
    14221 ggtgtgtagc cgaattgaac attttcaaaa cgaactttgt atggtgtatc tttttcttct
    14281 ggaaggccag atttttcatt ggacatctct tcttcatcca acacttcaaa tacccgttcg
    14341 gctgaagcaa ctgttgattg gatagtgttc atcaaacttg caagttgagt gattggttga
    14401 gagaactgtg ttgtatattg caagaacgct tgaacatccc ctaatgtcat gttcccattt
    14461 gcaactttta ctccgcctag tacagcgacg aacacatagc ctagattttt aacgaaattc
    14521 atcaacggca tgatgattgc cgaaataaat tgagctttcc aaccagcggc atacagattc
    14581 tgattttctt tttcaaatac ttcctggtct ttttcagtat gattgaatgt tttaacaatg
    14641 gtatgaccac catatgtttc ttctacttgg ttattcaata aacctaaact tttttgctga
    14701 tctgcgaaaa acacttgtga tttcggcgct acgatcatca cgatgatcaa gcttaaaggg
    14761 atcatcaata acgcgactaa cgtcaattgc cagctgattg aaagcatcat cacgatgacc
    14821 ccaatcaatg tgactgcact agttacaaat tgagtcaaat tttgctgcag cgtgcttgcg
    14881 atgttatcca tatcattgat tgctcgagac atgatatccc catttgtatg tgtatcataa
    14941 taggaaatcg gtacacgatt cattttggct tccaaatcat gacgtaattc ataaactgtt
    15001 cgttgggaaa cacgtgtcat aataaattgc tgtaaaaagt tgaatacagc agaaatcaaa
    15061 tacatcacga ttactgtcgc aatgatctgc gcgattttat caaagtctat cggaaatttt
    15121 gttacttgtt ggccttgttg catctgttga gcgccagcca ttacaccttt gaatatttct
    15181 gtggttgctt tccccaagac ctttggtgtt tggatttgga agatcacggc tgctattgct
    15241 agtacaaata cagcgatgat cgcaaccata cgtttagaca tatagccaaa caatcggcgt
    15301 accgttcccc agaaattttt aggcttttca ccttttacac cgagatttct gccaggtcca
    15361 ccatgtcctg gaccgcctgc tggtccatga gagggacgtg tgtttgtttt actcatgcta
    15421 agtcctcctc tcttagttgt gaatgaacga tttcttgata agtttcgttt gttgctaata
    15481 gttcttcatg tgttcctttg ccaaccagtt ttccttcatc tagcacaagg atcatatctg
    15541 catccattac tgtacttact cgttgagcaa ctaaaacggt gatactttct ttcatattcg
    15601 ttttcaatgc ttggcgaaga ttggcatccg ttttgaaatc caacgctgag aaggaatcat
    15661 caaacacata gatatctgct gttttgacta atgcccgtgc aattgccaga cgctgtcttt
    15721 gtccaccaga gaagtttcct cctccttgtt ccacatggct atctaagcca tcttccatct
    15781 ctgaaacaaa atctttagct tgtgcgattt ctaatgcttt ccaaatcatt tcatctgttg
    15841 catccggctt accatactgc atattgtctc ggatcgttcc agagaacaga actgcttttt
    15901 gaggaacaaa gcccattaat tctcgcaaat tatattgagt catgtcacta atgtccgttc
    15961 catttatttg gatcgaacca gattcgatgt catataatcg agggatcaaa ttgactaagg
    16021 tcgttttacc tgaaccagtc ccccctatga ttgcgacgat ctcgcccgac ttggcttgga
    16081 aatcaatatc ttccaatgca agtttttctg ctccatgata tcgataattg acatgattga
    16141 aggccaatgt tgcgtttttt ccagcaaaag aaactgtttt aggattttca gggtcatgga
    16201 taccgatttt ttcatccaac acttcattaa tacggtcagc tgaagcttgt gcacgaggca
    16261 ccatgataaa aatagcggaa agcatcataa agctgatcaa gatctgcatc gcataagtca
    16321 taaatgcaat cagattaccg acttccaaag tcatatctgc tatgtagtgt ccaccaaacc
    16381 aagtgattgc tacgtttgta ccgctcatga tcaatgtcat cattggcatc atcaatgcga
    16441 cgatcgtatt aactttgatt gccgtatttg tataatcttt attcgctaaa tcaaaacgat
    16501 tttcttcaaa gcgtgtctta tcgaatgctc gaatcactct gacccctgtc aatccttctc
    16561 gaaataccag gtttaaacgg tcagttttct tttgcatact tttgaataat ggaacagcaa
    16621 agtacatgat tccgccgatc aaaataatca ttactgggat gacaactaag aagatttttg
    16681 tcaactgatg atctttttga taagcaagta tgctcgcgcc aatcaacgtg attggtgcat
    16741 tgatcatcat acgtaaaaac atttgtgtaa ccatttggat ttgagtcaca tcattggtcg
    16801 ttcttgtgat caaagaggcc gttccatatt tatcaaacgc atcttttgtc agactctctg
    16861 attttttata gacatccgta cgcaattgct tacccagttt ctgtgattca cgagtagcaa
    16921 aaaatgtatt tgcgatagca gctaagatac tgatcaaaga aaagccgatc atcacaaaac
    16981 ctgtatgcca aatataatcg acatctcctt gcgctacccc tttatcaata atattggagg
    17041 taagtgtcgg caaatataaa tctgccagta cttggatcac catgaaaact gcagctgcaa
    17101 ttgctgaagt caaggagatc cgttttacga tttttagcat ctagttccct tctttctatt
    17161 tatatactcc gtttttcagc caagaaagtt tcaaattgaa ttcactgatt gcttgctcta
    17221 ctgagtaatc ttcagatgtt gaaaataagc gatacgaatg cgcaattgtt gtaaatacag
    17281 tattcatcac taattggatc agtaattcca attcatgatc attttttact ttcagcttcg
    17341 tccgatcgat caattcaagc aactcttttg catcttgttt gtgttcttta tgtggatcgt
    17401 gaggcgtttt ttggcgactc gtatgaggag cgacttttct tgaggcacgg taatccatgt
    17461 tcataaacaa gttacgataa aaagaagcat tctcgccttc caaaatctca taaatcattt
    17521 tagaaaaata ggattcgaat cctttgaata gatcaccatc ggattctttc attagttgta
    17581 acatatcttt agagctgtca cgtctcattg tctcaaagta ataaaaataa agatcctctt
    17641 tatcttcaaa atactgatag aaactgcctc tagggatatc cgctaatttg acgatattag
    17701 caatcgaagc ttcttttaag ggtactctag aaaactcgat tctcgcagcc tcgattagtc
    17761 ttttttgttt ttctttaggc aaatggaaaa atgtctgtgt cggcatatgg attctccttt
    17821 ctttcaagat gacacattgt catatgacgc tatgtcatta taacacctcc tacctgtttt
    17881 gcaagacatt tgcatagttt ttttcattat catccgatac attaaaaaag tgataagagg
    17941 aatccttcca tttgaattaa tgagagttgc ccattaaaat agccacatac taaacaaagg
    18001 atgagataaa tggcccaatc aattagtgtc caagacttca ataaattgcc tctcgatgct
    18061 gacagcatcg ttttagatac aagaaatacc ttagattaca caaaaaacca cttaagccac
    18121 tcgctttcta tccccgctgc tatcttgcca agacaattaa aaaatctaga tccaaagaaa
    18181 ctttattata ttctaagcta tacaggcagg cgatcagaag cattagccga tcaacttact
    18241 gctaatggtt ttcgtgctgt ttatatcatt ggtgggatgg aagctcttca gtcgagtgtt
    18301 gcttgaatat tgcttgttag attcaaaaga ggctgtgaca aaaaatcgtg tcacagcctc
    18361 ttttataccc tgtctttttt tagttattta ttcttcaacc ttatcaatat gacttgatag
    18421 ccttttcttt ttcgagtaaa ctgattttgt tagtcatagt tataacaatc atagcaataa
    18481 aaggagaagg taagcatatg gcatctgttt tagtagtcaa aggtcatccc ctaactgcag
    18541 aagaatcgcg cacagttaag gcattgacgt cttttttaac aagttataaa gaaaatcatc
    18601 cagatgatga agtgactgtt ttggaacttt atcgcgatga tattccggaa atcgatgaag
    18661 aattattatc aggttgggaa gcattacgtg ctggtgcaga attcacttcc ttatcagaaa
    18721 gtcaacaaca aaaaattgct cgtttcaatg aattgactga tcagttcctt gctgctgata
    18781 aaatcgttat cgcaaacgcc ttatggaatc taaatatccc aacaaaatta aaagcttggt
    18841 tcgataccgt caatgtagct ggaaaaacgt tccgctatac agaaaacggg ccagaaggat
    18901 tagtgacagg taaaaaagca ctgcacatcc aatctaatgg cggtgtatac aacggacaag
    18961 actttgcctc tcaatatgta aaaggtattt taaactttgt aggcatcgat caagtagatc
    19021 agctattcat cgaaggaatc gattatgacc ctgaccgtgc agatgagttg atgcaaaatg
    19081 cattagataa agctgctgct ttaggtaaat cattttaaaa attgagataa atgcatacaa
    19141 aagagacaga ggaaaaaatc ttcaaagcag catttgtgcc ttgga
//
LOCUS       DACBZK010000051        18895 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.053, whole genome shotgun sequence.
ACCESSION   DACBZK010000051 DACBZK010000000
VERSION     DACBZK010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18895
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.053"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(21..251)
                     /locus_tag="IVD66_001904"
     CDS             complement(21..251)
                     /locus_tag="IVD66_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146109.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(687..1253)
                     /locus_tag="IVD66_001905"
     CDS             complement(687..1253)
                     /locus_tag="IVD66_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP6146110.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1253..2209)
                     /locus_tag="IVD66_001906"
     CDS             complement(1253..2209)
                     /locus_tag="IVD66_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HAP6146111.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2209..2865)
                     /locus_tag="IVD66_001907"
     CDS             complement(2209..2865)
                     /locus_tag="IVD66_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAP6146112.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3235..5253
                     /locus_tag="IVD66_001908"
     CDS             3235..5253
                     /locus_tag="IVD66_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP6146113.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     gene            5680..8094
                     /locus_tag="IVD66_001909"
     CDS             5680..8094
                     /locus_tag="IVD66_001909"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HAP6146114.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8442..9995
                     /locus_tag="IVD66_001910"
     CDS             8442..9995
                     /locus_tag="IVD66_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAP6146115.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10376..12160)
                     /locus_tag="IVD66_001911"
     CDS             complement(10376..12160)
                     /locus_tag="IVD66_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6146116.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12175..13896)
                     /locus_tag="IVD66_001912"
     CDS             complement(12175..13896)
                     /locus_tag="IVD66_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6146117.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13996..14757
                     /locus_tag="IVD66_001913"
     CDS             13996..14757
                     /locus_tag="IVD66_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP6146118.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15724..15992
                     /locus_tag="IVD66_001914"
                     /pseudo
     CDS             15724..15992
                     /locus_tag="IVD66_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16664..>18895
                     /locus_tag="IVD66_001915"
     CDS             16664..>18895
                     /locus_tag="IVD66_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146119.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
BASE COUNT         6205 a         3353 c         3786 g         5551 t
ORIGIN      
        1 ctcattaaaa agcataacca ttactccgat ctgtttttaa aattagtttc tacctctaat
       61 atatatcgag tttttatttt gccttcagag aatactgttt ctttttttgc agttacaggt
      121 tgtttatttt cggaaaaagc taatatagct aagattgaaa catccatctg gaatttatct
      181 tttttactgc tttgatcata aaagtctgca tattcatcac tgatattttt tctaataaat
      241 tcttccatca taaaaatcac ctcaaaacga ttatacgaac ttacgttctt gttgtaaagc
      301 gatatttgag gggcaaaaaa ggggcataat ttgactgata ttaagttagc tattgatata
      361 tgaatgacat acaaaaatat aaaatctttt aaaaatgctt atatatcaat gtttttgcca
      421 ttcttttata tatctgttat atgtcaaaaa aatgtgttca atttcaattt gtatttgaat
      481 aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaat caaaaacagc
      541 ttctcatgtt tttgatttgg ttggacttat taccgcagat ataagctttt gagcaccgtg
      601 aataaagagg ttatgaaatc aacgctctaa cctgagtatt agagaaaaaa acgcaaaaca
      661 tatcatttat gttttgcgtt ttttatttat ctttttttct caatacaata taaaataggc
      721 ggctggttct tttggttgat aaaccgataa ttcagcacat tatatgtttc ctgtggcagt
      781 ttggaacaaa aagaatcaac catatccagt tctttttctc caccttcatg accatagtag
      841 acgacaagga tcaatcgtcc gcgaggcaca agtcgtttca atatttcttc catagctgtg
      901 cgtgtagtct ctggcatagt gatgattgct ttatcacttt ttgggagata ccctagattg
      961 aaaatccctg ctttgagatt ttgttgttca gctatcactt ctcctaacgt ttcgtggcct
     1021 tgtagaaaca atgagacacg ttcttctaac tgacgctgtt ctagcctttc acgagtagca
     1081 tcgattgctt gttgctggat atcaaaacta tagacatgac cagtttttcc gatgtgttct
     1141 gctagaaaaa ccgtatcgtg gccattgccc atcgttgcat ctacgacgtg atcccctggt
     1201 tgcaagattt cttgcagtaa tgtatggctg aaatgcaaag cagtttgcaa catcagacgc
     1261 tcaccttttt ccgtacatca tattttcctt ggaagctatc tctgcgaaga agttcttcat
     1321 caattgcatt caagacttcc cattttttca agctccacat tggtccaatc aaggaatccc
     1381 acggcgcatc ccctgtcaaa cgatggatga tgatctcttt tggtatcatt tccagctggt
     1441 cgcaaatgac attgacatag tcaggacggc tcattaattg aaggcgacct tcatgatagt
     1501 cccgcaacat tctcgttttg cgcatcagat gcatcaaatg gagcttgatt ccttggatat
     1561 ctgaatctaa aatggtgcgt ctgacatttt ctttcatcat ttctaaactt tcgcctggta
     1621 atccgttgat caaatgcgta caaacacgga tattatgttt gcgtaattta gccacgccat
     1681 ctaaataagt ttgataatca tgtgctcggt tgatcagttt tgaagtttct tcaaaagttg
     1741 tttgcaatcc aagttctacc cataaataca tccgctcgtt cagttcagca aggtaatcaa
     1801 ctacttcatc tggcagacaa tccggtcgtg taccgactga taatcctacg acacctggta
     1861 aattgactac ttgctcaaat cgttctttga ttatttcaac tggcgcatgg gtgtttgtaa
     1921 aattttggaa ataaacgatg tattgttgga catgaggcca tttttgatgc atcatgtcga
     1981 tttctttctg gaattggatt ggaagagggt cttcaggtgc aacgatcatg tctcccgaac
     2041 cagatacact gcaaaaagta caaccgccat gggcaacagt cccatctcga ttcggacagt
     2101 caaatcctcc atcgatcggc accttgaaaa ttttcccgcc aaactcattt cgtaaagcgt
     2161 aattccaaga atgatatctt ttatttcctt ctgaataagg aaaagtcatt aaaagtcctt
     2221 ctttctgtaa gagttatcta tttgttttct tttttctcta tacactggat aagtcaggca
     2281 cagccaagaa agactgagta agtagccgcc gatgatatca gtaggaaaat gaacgcccag
     2341 ataaatgcgg cttatcccga cacttactat aataaacatc atcagcaatt gaagcaatgt
     2401 gcgtaaggtt cttttttgaa caaaagctgg aagcagaaat agtaaagaac cgtaaagaat
     2461 catactgcct gctgcatgtc cactagggaa actgtaactt gtttcaacta ctaagtgcgc
     2521 caatgaagga cgctctcgca tgaaaaatag tttgatcacc gggttgatga ttccagcaat
     2581 tacaataaat ccagaaacga accaaaatgt ttctgccctt tttttcttat accacatcca
     2641 taaagccgca caagcaaata aaatgatgac ggtaagagga ttaccgaatt tagtcataaa
     2701 gagttggtag ctgttcagat caggataaga agctctgaca atgcctgtaa accactgatc
     2761 gaaaccagaa agccacgaca gatggaactt tacgatccag cccaaaatga aaaacaggac
     2821 aagaaagaag ctaccagcca cctgaaatga tgttttatat ttcatacaat tcctcctttg
     2881 aagcaatgac ttattatagc atttttggtc cagcgaaaaa aacggtaaag agataaaacc
     2941 aatgtatgat tcctctttga ataaccaata ttcttataaa aaaaataact gtaatcggaa
     3001 agacattttt tggtaatgca aatgaaatgt tagggaaata aaatcagtgt ttttcgaaat
     3061 ccttttaaac aagaacgtag acgtaggaag aacttgaaaa tgaacagaag ttgttcatta
     3121 cggtaaatta caatatgatt acaaaaaaca acaaagctct taaataactt ttaataaata
     3181 ttaagagaag ttataattat taataataga taaattgaag ttggaggata gaagatggaa
     3241 aacattgcaa gaaaagaacg gagacgttta gaacagacca aacgttttcg aaaagcaaaa
     3301 cgaggggcag caatcgtggg aactgcgatg gtaggctgtt ctgtcgctgc cccattagta
     3361 cagccggttc ctgttcaagc ggatgaaaca cctgttcagt tcggcgcaag aatcaataca
     3421 gcggcattta tcacagaaat tgctacttat gctcaaccaa tcgctcaagc caacgatcta
     3481 tatgcatcag tgatgatcgc acaagcagtt gtagaaagcg gttggggcag tagtgcgtta
     3541 tctcaagcac cttattataa tctttttggg ataaaaggca gctatcaagg acaaaccgtc
     3601 tacatggata cgcttgaatt tttaaataat caatgggtaa ataaaaagga gcctttccga
     3661 caatatcctt cttttgctga atctttcaat gacaatgcct atgtacttag aaatacttca
     3721 tttggcaacg gttattacta tgccggtact tggaagagca acacgaaatc ctatacagat
     3781 gcgacagctt gtttgacagg gcgttatgcg actgatcctg gttacgcagg caaattaaat
     3841 aatatcatcg caacttacgg attgacccaa tatgatacac cagctagcgg aaacgcaggc
     3901 ggtggagcga ctacaggtgg caataatact ggaagtgcag gtagtactgg cggttcaagc
     3961 aattctggta atacaaactc aggttcagca acttcgacca cttatactgt ccaatctggt
     4021 gattctgttt ggggaatctc aaataaattc ggtatcacaa tggatcaatt gatccaatgg
     4081 aacaacatcc aaaacaattt catttatcca ggacaaaaac tgacaatcaa aggtagccag
     4141 gaaaatggct cttcgacgaa taattccggt aacaatacca actcttcagg aaatgctggt
     4201 acatcaaacg gaggacaaac aactggtgcg aaatacactg ttcaatctgg tgattctgtt
     4261 tggaagatct caaatgatca cggaattacg atggctcaat tgattgaatg gaacaatatc
     4321 aagaacaatt tcgtttatcc aggacaacag ctaatcgtat caaatggcgg ttcttctaat
     4381 gctggagcaa atactggctc aaatactggg aatacaagtg gctctagttc gtccagctca
     4441 agttcttcta atacagcttc aggaacgaaa tatacagtta aagccggaga ctctgtttgg
     4501 agcgtctcaa ataaatacgg aattacgatg gctcagctaa tccaatggaa caatatccaa
     4561 aataacttta tctacccagg acaacaactg actgtttcaa acagtggatc aacaaacagc
     4621 acgtcaggta atacaggttc gtcaaccaat acaaataaca gcagttcagt taatactggc
     4681 agcagttcgt ctcaaggcac ttataccgtg aaagcaggtg aatctgtttg gagcgtggca
     4741 aataaaaacg gcatcacgat ggatcagtta atcgaatgga ataatatcaa aaacaacttc
     4801 atttatccag gacagcaatt gatcgttaaa ggtggaactt cggcaaatac aaatacaggt
     4861 tcaactactt ctgcagcgaa accaaataca ccgaatacgt ctgctacgac aagtacatca
     4921 tccactggta atacgatgta taccgtgaaa gcgggcgagt cagtttggag cgtagcgaac
     4981 aaacatcata tcacgatgga tcagttaatc gaatggaata atatcaaaaa taatttcatc
     5041 tatccaggac agcaagtgat tgtgaagaaa ggttcatctc aatcaacaaa ccaacaatca
     5101 gttactggtt cgaaaaccta tactgtgaaa tctggagaat ctgtttggag tgttgctgac
     5161 agtcatggaa ttacaatggc tcaactaatc gaatggaaca atattaagaa caactttatt
     5221 tatccaggtc aaacgttgat tgtagctaaa taaaatagct gttcgaagaa ataacgattg
     5281 aattccacaa aaatatttgt tactataagg ctacttaaat atgacaacac ttgaaaagga
     5341 agtagtaaaa agactgaagt ttcagagagc gcatggctgg tgagaatgtg cacggatgct
     5401 tttgaactcg cctttgagtt gcccttgctg aatacccgag taagcaagcg gcggtgacgg
     5461 ccgttacaac gttcgaggcc ttttcactaa ggtaaaatta ggtggtaccg cgtagattac
     5521 gtcctataaa aagagcaatc tttttatagg atttttttat ttcttttgtg aagtttgaga
     5581 aaacaaagca aaaggaaata aaaataaaca gattctgccg gttttttcgt tatatttata
     5641 atagaaacaa gtgttttcaa tagaacagga ggacagcaaa tgagttacaa tcataaagaa
     5701 attgagaaaa aatggcaaaa atactgggca aaaacgaata ctttcaacac ccatgatgat
     5761 cctgaaaagc caaaatttta cgcactggat atgtttccct atccatccgg tcaagggcta
     5821 catgtagggc atcctgaagg ttatacggca acggatatcc tttcacgtgt gaaaagaagt
     5881 caaggataca acgtgctgca tccaatgggg tgggatgcat tcggtctgcc tgctgaacaa
     5941 tatgcgctag atacaggaaa cgatccagct gagtttaccc aaaaaaatat cgaaacattc
     6001 cgacgccaaa tcaattcttt aggatttagt tatgactgga atcgcgaagt gaatacaact
     6061 gatccggagt attataaatg gacacaatgg atctttacga agctttatga aaaaggtcta
     6121 gcttatgaag cagaagtagc ggtaaactgg gtacctgaat taggaacagt tatttcaaat
     6181 gaagaagtga tcgatgggaa aagtgaacgt ggtggctatg atgtagtcag aaaaccaatg
     6241 cgccaatgga tgctgaaaat cactgcttat gctgatcgct tattggatga tctagaatta
     6301 gttgattggc cagaaagcat taaagaaatg caaagaaatt ggatcggtcg ttcagtagga
     6361 gcaaatattg aatttaaagt ggctggtacg gataaatcct ataccgtatt tacgacacga
     6421 ccagatactc tattcggtgc aacttactcg gttcttgcac ctgaactaga tcttgttaga
     6481 gaaattacga cccctgaaca aaaagctgct gtagaagctt atatcgaaga gacagctaaa
     6541 aaatcagatc taaagagaac ggatcttgca aaagaaaaaa caggagtatt tactggtgct
     6601 tatgcaatca atccagttaa tggcaaggaa atcccaatct ggatcgccga ttatgtatta
     6661 tcttcatacg gcacaggagc catcatggct gttccagcac atgatgaacg tgactttgaa
     6721 ttcgctcaaa ctttcggact agaaattctt ccagttatcg aaggtggaga tgttgaaaaa
     6781 gctgcttaca cagaagatgg tacgcacatc aactctgaat ttctagacgg catgaacaaa
     6841 caagaagcaa tcgataaaat gaatgaatgg ctagaagaaa atggcgtagg gaaaaaagaa
     6901 gtcagctatc gcttacgtga ctggctattc tcccgtcaac gttactgggg tgaaccaatc
     6961 ccaatcatcc attgggagga cggaacagtc acagctgtcc cagaagaaga gctaccatta
     7021 cggttgccta agacaaaaaa catcaagcca agcggtactg gagaatctcc attagcaaat
     7081 atcgaggagt gggtcaatgt cgttgatcct gtaacaggta aaaaaggccg tcgcgaaacg
     7141 aatacaatgc cacaatgggc aggaagctca tggtattacc tgcgttatat cgaccctcat
     7201 aacaaaaaag aactagcaga ttatgaaaag ttgaagcgtt ggctaccagt tgacatctac
     7261 attggtggag cagaacatgc ggtacttcat ttactatatg cacgattctg gcataaattc
     7321 ttatacgata tcggtgttgt tcctacaaaa gaaccattcc aaaaactata caatcaagga
     7381 atgatcttag gcgaaaacaa cgaaaaaatg tcaaaatctc gtggtaatgt agtcaatcct
     7441 gatgatgtgg tcgaaactta cggtgcagat acactgcgca tgtacgaaat gttcatgggg
     7501 ccattagatg cttcgattgc ttggagcgaa aatggcttag aaggaagccg taaattcttg
     7561 gatcgtgtat ggcgtttgat cgttgatgag aacaataaaa tgcgtgaccg tatcactaca
     7621 ttgaatgatg gcaagcttga taaagtgtat catcaaacag tgaaaaaagt gacagaagac
     7681 tatgaaaatc ttcatttcaa tacagcaatc tcccaattga tggtctttat caatgaagcc
     7741 tataaagtgg acgctctgcc ttatgaatat atcgaaggat ttgttcaact actcgcaccg
     7801 attgctcctc acatgggtga agaactatgg gcaatccttg gaaatgatgg tggtatttct
     7861 tacgcaccat ggccaacata cgatgaagca gcacttgttg aagacgaagt agaagttgtt
     7921 ttccaagtaa acggtaaagt tcgtgcgaaa agcaatgttc cccgagactt aggaaaagat
     7981 gagctagaaa aagcagcatt agccaatgaa atagtgcaag aatatattga aggcaaaaca
     8041 gtcagaaaag ttattgcggt accaaacaag ttagtcaata tcgttgctaa ttaattggct
     8101 ctttgtcaat aaggactgat gagttgtgca aaatcaaatc tgggccagaa tgaacttcat
     8161 tctgtctcag attttttgtt atttcaaatt gattaattga ttgatcaaaa aggttttgat
     8221 tttcatgttc tcaaacacgt tcaatgtctt tttcttctga atggtcttgt aagagatctc
     8281 tgtaatcatc aaatttttgt ctattaatct tagtattttt tgatgtataa actacctgaa
     8341 attgagagta cataccaaat tcataaattt tttattagtg ggactagtga ttgtatggat
     8401 tttgacgcat aatgaatgaa gtatgagaaa aggagagaca aatggatcaa gaactattta
     8461 ttatcgaagt attatcagct aaacaaaaaa ttatcgagaa agcgaaaaaa agagcgaaaa
     8521 gaataatgtt caagctttta agcttagtat ttttctctgg tttgcttttt ttcggagctg
     8581 tatcgttcct atatcgccat atgagtgcag tagtccgttc agctgaaggg atgcaaaaat
     8641 taaataattt gtatcacttt tcgtggggag ttggcggaat aacaattgtt gtgcttattg
     8701 tttttcttct acttatttgg ctccgttacc atcaattgtc gcgtcatttc gatcaatggc
     8761 ttagtcaaag agcacaacag tttttacata ataaaccaac ttctcaagat gatgactatc
     8821 tttattttga gaagacttcg acgagtcaag cttttcggat acaaaaaagt gattgccagt
     8881 tattgctgag atcacttgat gatttaccta tctacttagg cgaaagcaaa tcaaaattcg
     8941 gaatgaacac attccatatt tttttactag aaaacgaacc cagatgggaa aaaagccagt
     9001 cttcgcctgg tggatacctg acaactaaga tgagtacatt agtcactggt tttttcctca
     9061 ttcttttagc tggaacaatc tattatggga gatacactca gccaaaaatg tcttctcata
     9121 taaatgctgc ttctcacatg acaatgaact caactaacga tacgcatata caaaagacaa
     9181 atgaagggtt gttagctgat cctaagcaaa aggtaaattt gacaacacaa aagataaatg
     9241 atctcaaact tgatacagag acgcactctc tctatatgac aacagatagt ggtgctaatt
     9301 gggtatttgt gccgattgat tcgcaatggt tgcgttttgg cgaatacacc ctgacaacgg
     9361 ggctgattcc tgaaggttat tggatggaca acacatatga tatttccgcc gatttctcat
     9421 ggtttatcta ttcttctggg gatgatgtac gtctgctgac ttcaagagat aatggtaaaa
     9481 catggcaaac gtctattatc acccaatcag ttcagccgat acgttatcga aaagcggtat
     9541 tttatggcaa cgatggtcta tttatctgta catcagccag tgggatgtct gcagaaactt
     9601 tgtacattta cactactatg gatggcggaa tcacttggat aaaaagtgga agtacaatga
     9661 tcaatcagcc agtacaaaat gtcagcttcg ttacaacttc tttaggtttt gtttcgacac
     9721 gtgaaagttt gttttataca aacaacggag gacgctcatt caaagaatca gttctgtcga
     9781 ttccggaaaa ctatcagaca ggggggatag atctttttca atcaccaaat gaagttactc
     9841 aaataagcgc gaatacgtta gagacaaaat tttatttgtt gaaaaaagga ccaatcgatg
     9901 cagggaaaat gtttgcctgc ctcttccgtt caactgataa cggggaaaca tggcaattcg
     9961 ttcagcaact atcgcaagta gaacaaggag attaaagaag agagattgtg agcctgacgt
    10021 tcagcaccga gtcacaagaa acaaattcaa aaaacagctt ctcatatttg ttgaatagtg
    10081 taactcgtga ttcggagttg acaagagcaa caagaagcga ttttgaagta tagcttctcg
    10141 tattttacaa gatcgtgtct tattgccgat aggttgtctc ttgaacaccg tttattcgta
    10201 aaaagggatt gtgacaagtc ttttgtcact acttaccgaa cgaaactgaa ggagctatcc
    10261 aaaaagtatc attagtatta ttctttgtgt ttctagtggc accactagta catttaaaaa
    10321 agctatcgat catggactaa tcatacatga tcgatagctt tttagataat gtttgttacg
    10381 ctatctgaaa ttgactatta taaagactgg cataaagcgt tggtgattgg agtagttcag
    10441 aatgtgttcc tttttcgacg atatcgccat tcttcattac aaggatcatg tctgcatttt
    10501 caatcgttga caaacggtgt gcaatcacaa aacttgtcct atcttttgtc acagcttcca
    10561 ttgcttgctg aatcaatgct tctgttcgtg tatctacgct agaagttgct tcatctaaaa
    10621 taacgacagg aggattcgct agaatgactc gagcaattgt caataattgt tgctgtcctt
    10681 gagataacgt gccgttttcg ctagaaatga tcgtatcata tccgtctggc agtgttcgaa
    10741 taaagtgatc acattgtgcg atttcagccg cttcgataat ttgttctctt gtggcatcca
    10801 ttttcccgta ggcgatatta tcagctaccg ttccttcaaa cagccaggta ttttgtaaaa
    10861 ccatcccaaa agaacgacgt agttctccac gtgaaagctt ggtaatatca agaccgtcga
    10921 attcgatctt tcctttattc agttcataaa aacgcatcag cagattgact aaagtcgttt
    10981 ttcctgcacc agttggacca acgatcgcta ccgtttgttt tggctttact gaaaaatcga
    11041 cttgattcat caatatttta tctgatgtgt aaccaaactg tacatttttg aaagctattt
    11101 ttcctttcgg ttgttctaaa agtcttgcat ctggaaggtc tggaatttca tctgtttcat
    11161 ctaatatctc aaatatccta tcgattgctg ccattgcgga ttggatcgag ttgatcacat
    11221 aagaagcggt agaaattggt tcagaaatct gattgatgta ctgaagataa gcttgtaaga
    11281 agccgatcgt cacaccacct gatagaacaa gcatagcacc gaataccgca cttatgatga
    11341 aggcgagttg attaatgaaa cgaatggccg gatagatagc acagttcata aattgagcac
    11401 gtttaaaagc gttgtattgc tttttattta cttcgtgtat agcagcttct gcatgagctt
    11461 gctgattgaa tgttttgacc actagattac cagctaagat ttcttccatt cgattattta
    11521 aaacacccag ttcatactga ttctgttcag aaatctgttt gtttttgttc gcaatcttag
    11581 ttgtaacaat tgaactgcca acgatcagca ataagacgag caaagtaagc ttgctttcga
    11641 tataaaacag catcagacca gcagcagcta ttgttacgac agaagtaaaa aattgattga
    11701 tacctgtcaa taacacttga gaaagttgat tgagaccggt agttgtccga ctaatgatgt
    11761 cacctacttg atgattgtca aaaaacgaca tcggtaatgt tttgaatttt tttgtgattt
    11821 cttttcgcac cctcaatgtg atcttttcgc ttaacgctgc cattgtccgt tcctgaataa
    11881 atgaagtgat gctgcttaag actgaacagc cgatcagcaa taagacaggg aacaacaatg
    11941 cttgtttgat atcactgaaa gaaagctgtc caatacctgt ttttcttatt tctgataaga
    12001 gatcatcgat cccgattccc atgatcaagg gcatggctac gactaatagg ttcccgaata
    12061 aactgcatag aaacaatccg taaaaatatt tatgttcagg tttgatcatt ttccaaaaac
    12121 gtatcaaagc acgcgtgttc aacgtttttt tcttttccat cgtatccctt ctttctatat
    12181 tccttgtgat tttgcaaact cctgataagt ttggcaatta gacagtagtt cttcatgagt
    12241 accttgtcca acgatttttc cttcatctaa aacaatgatg ttatctgctt gttggattgt
    12301 actgaggcgt tgagcaacaa tcacgagagt tttctccgac atgtgtttat gaagggctgc
    12361 tcttaatgct gcatctgttt tatagtctaa agcggagaaa ctatcatcga atacatagat
    12421 ctctgctggt ttgatcaacg ctcgagcaat acatatccgc tgtttctggc cccctgaata
    12481 attagaaccg ccttgagcaa caaagctgtc caatccgtca ggaagggtgt ccactagttc
    12541 ttctaattga gcgatcttga tcgctttaga caactcttct gttgaggcat attcatttcc
    12601 catctgcaag ttgcttaaaa ttgtcccgct gaataagaaa gccttctgag ggacataact
    12661 gatgtgggag cggatctgtt cttgagtcat ttgagtaaga ggaataccac caagggttac
    12721 ttttcctatc gtagggtcac taagtctcaa gagaagtttc gccaaactac tttttccaga
    12781 tccggtcccg ccaacgatcg ctgttgtttt tcctttaggt attgtgaaat caatatcttc
    12841 tagaactgga tcagagattt cagtatattt aaatgtgaca tgttcaaaag cagctgcatt
    12901 tgtctgatca aaggttggtt cagctactgt tttgatcgtc tcttcctcaa tttcgatctc
    12961 tgcttgcagt atttcttcta tccgtcgtaa tgaggcaaac gatttaggga taatgaccaa
    13021 taccatagct gcgatcatca agtaagcaag tgtcagcata gagtattcga ctacagcagt
    13081 cacgacaccg atttgtaatg ctccttctgc tacaagattt ccgccaaacc acaaaataga
    13141 agcataaacg attcccatga gcaaaaaagc aattggagtg acccaagcaa atattcggtt
    13201 cactttgatc atttgattag catagtcagc aaagctctta ttcgttcgct tttcttcata
    13261 tgattgatta tcaaaggcac ggatcatatt aatcccagta aagaattctc tcaatgtgat
    13321 ggtgatccga tccatttttg gctggatact caaagataaa ggtgcccctc gtttcatcag
    13381 tcgataaaca atccatacat aaaaaacaac agagatcaat gtaacccatg ttagtaatag
    13441 agaataacga aacatcatga gaatggtgaa aacgcaaata accggtgctg gtaagatcat
    13501 ttggcaaaat aaaacaatca tttgctggac attatcgaca tcattcgtca ttcttgtcaa
    13561 aagagatcca gaactaaaac gactgatatc cttcattgac agctgttgga atttacggaa
    13621 atatttctcc cgcgtttgga atccaaacct agcggaagcc aatgctgaaa agtaactaga
    13681 ggcaactgca gcgattgttc ctagaaacgc tacaagcagc atttcaactc caattttttt
    13741 tataactgag gcttcgccac ttgctatacc tgtgtcgatc agctttgcta ctaattttgg
    13801 tacacctaat gtaccggcga tttctaaaca gatcatcaca aaggtaagga gagcgagtcc
    13861 tttgtttttc tgtaagaatg tttttaagat agacatatta ttcctccttt tttcctgata
    13921 cttttcgatt ctataccttc aagtaacttg aaggtcaata gaaaaaagaa taaactgaaa
    13981 aagaggtgag aaaaaatgaa aaaaatgtat acgattggcc aagtatcgga actatttgat
    14041 ttgccaaaat caacgatccg ctattgggat gaacaaggat taatccgttc aagtagacaa
    14101 gaagagaatg attatcgatt gtttgatatc gatgatattt ttatgcttta tgatatcgtt
    14161 ttttatagaa aattagatat accgatcaaa cagatgaaga atttatatgg aaaaacattg
    14221 acggagttat atgagacact tgatgaaaca gaaagaagaa tccataaaga actggtggtg
    14281 atgaaacaaa aacaaaaaga gataagggag caaaaaaaac agttgaaatt gatgatcgat
    14341 acaaacgagg aagaatttcc tgtagaagag atcccttttg actgtatgat ctcaacggag
    14401 tttgaagata ttgtggaaat caaaaaattt ctacctaact attcaagctt tgggatgatg
    14461 agtatgccag cttccagttc acagacgatg tatggatttt ttatcgaccc tagtgaagta
    14521 catttattta ctcaagacgt gatttgggag aaaaaagata cggctgttta tcgtcgattc
    14581 ttattgaaat ccgagatgaa ccatgcggaa cgtaataata ttttagaaat cagagaaaga
    14641 atgtatgaaa aaggatggaa aacaggagaa gtgatcggcc agtatctatt gacgaatacg
    14701 gatgaaaaca atatcagaac tgaatattat catgcatgga tagaaatgaa aaaataggaa
    14761 atatgtgttt aagataactc gaaaatgatg gttgttttag ttataaagaa aaattttctg
    14821 gttcgattac gggtttaatg tgggggatta ttagtcgtgg atagatagaa ttttagtttt
    14881 ttagaggaaa tatgtcttta aaaatggaat ggttgcaatt cttagcgata tatacgatgt
    14941 aattgtcctc ttaaaaaagt atggaaaaat aattgtattg ggtgttatgt ataattcatg
    15001 gtgaactgag actaatgaga agaaaaattc atattgttat gagtgagatt gtatcagatg
    15061 agaatgataa attaaatagg tgcataaaag cattacactt aaaatacatt gttgcttaca
    15121 ttattacaat atgttaataa ggcaaaaata aatagatgga ttgaataaac atatttttta
    15181 atcaaatagt ccctactgtg actttcctca gctatcggtg atactaccga tagcattttt
    15241 ttgcttataa aataattata agtatttaga gatttttctt ctaacattct tcaaacaaga
    15301 aaaatcacaa aggttattgt tatttttata tattcttttt aagaatgatt gtttttttat
    15361 agaaatttta aaaaataaaa cacgttattg atggatagtt agtttgttat ttggtaatat
    15421 tatagaagtt gactggtagt gatttatttt tcgtcgtttt ataaaaatgt tattttttgg
    15481 aaaaattcac aaatatgtaa cgaatgtttt tctggaattt gctgtgttaa aaagcagtat
    15541 gactaatata aatactattg tcatttatgc aattttttat ggatagtaat tttagagggg
    15601 aatcaatgaa ggaagaatag aagggaaaaa tagttgcaaa tacgccagtt agcaaaaata
    15661 gcaatacatc ttcaagcttt aaaattcgag agaatcatct tggtagtgga atcaactaca
    15721 acaaaaggat taaaccaatt aatagataga attaccaatg gaaaaataga aaaggtagtt
    15781 attctataca aaagttgttt aattcgcttc ggttatgaac ttagtgaaac cctttgcaat
    15841 atatggtaca gaatatagaa attattgaca ttacagaaaa tgatgaagat ttaatacaga
    15901 ttgtcactat ttgtagatac cttttacaag gaaaccgagc caataaagct aagaagatga
    15961 ttaaggagtt gatggaagac gatacaagtt aagaaagtga aactacgccc aaataaagag
    16021 caaaaagagt aattggacgt ggaaaatgca agaaatgaac catcgattcg gtggacagtt
    16081 tattagtaat gacggtttga gaacatccat gacgagaatg aaggaacatc ctaaatgcgt
    16141 ttagttgaac caagtgccaa ataatatggc caaataagcg atcagttatc gatgaatccc
    16201 aagtattcta aactatatat tcattttgat gctaagcatt gatatatttt tttgggattg
    16261 atgaaggtta accaatacag ggactcactg atgaaattct agagtctgac cttggtatca
    16321 acgatttagt gattgtttct aatggaaaag tataaaagta tataagtaca ttaacaaaat
    16381 aactattagg gttacgctcc agcttgtgca aggcactggc aggaggaatc gtgaaatcat
    16441 aattatggtt aagccacacg gacaactaaa agtcatacaa agctatcgaa tcaatcaaca
    16501 gaagacaatc ggcaatcatt agctttgttt acagcttaca ttgcaacgct tgagttgaac
    16561 cgaaaatacg agggaggtaa cgcagccatt ttgagttggg gaatcttttt agaaaattat
    16621 cgggtacctt gttgtttagt caaaattata agggggagta atagtgagga acaaatttca
    16681 taaactgtta agtatgtttc tagttatgct tattgtgatc aatcaatttg ggaacataac
    16741 ggttctagct gagtctttag cagaacagcc agagcgttcg ctgacgatcg aagttgatca
    16801 agaggaggct gctttgggtg agcagttcca gttgcgagtc agaggaacac cagacctgct
    16861 aaatgcattg gtcattgata agagtgagga tttgattgaa ggggaagtga agcaactcaa
    16921 tgattacgaa cgtctgatta cttattcttc ccagcattca ggtaaatacg aattgaccgc
    16981 aagaagcggt gatattcaat caaatacggt ctcaatagaa atcagtgtac cagaagaaag
    17041 cacaagtgag tcttttaatg taccagaaga aagcacaagt gaatctttta atataccaga
    17101 agaaagctta agtgaatctt ttaatgaagc cagatcatct gagccatcta taacgcagga
    17161 atctcagatt gaaagacaag aggagctctt gaattatgac atcggcatct ctgctgagcg
    17221 ccccactttg ccgagcaggc atacacaaac gttaaaggga tacattcaag gaggcgctgg
    17281 cgatattctt gaagaatatg gggagatggt cgtacgagtt cctagagcat cgattggctt
    17341 aattgagttc attagagtgg aggtcgctga tgattcacct ttaaagccac tggcatttta
    17401 ccaagaaggc acagacgttg tttttccatt tacctttgat tatgaaggat taaatgaagc
    17461 cgctcagtcg tatacattca gtatcacgtt tgaagttgct ttctttcaat caggcggtac
    17521 tgagccaaat aatgactttc aagtgagtct tacttatgct gagcgagcag caaacacgga
    17581 attttcaatt acgcctattc cttcatcaag acccattttt tcgaaattat actatggctc
    17641 tagagaaatc gacagccaag gaaatcttgg gaatctgctg attgacgggc aagacgtgac
    17701 caacagtaat aaatttattt tgcaggtaaa ttatgaagga tcacgaaaag acggtgtagt
    17761 ggttaccgat gtactaccgc aaggaacaac tttggcaccg aatccgacta catggagttc
    17821 cactggaaat agagaaccta tttcaggtgg ggttcggatc gcagaagtaa cgaatccagg
    17881 tgaagcaaac gttagaactc attatgtttc cgaggaattt gtggacaaag tatcttttaa
    17941 taaggaaacg aatacacttg ttgtggactt tggtaatcta gcagagggtc aatcgtattt
    18001 tattgaatat gctcttgaag tgaccgatgt cgacttgttc aatgaaggaa gacaagagga
    18061 tgggttttct cggaatcgag cgagtatgac ctacaataat caggtaatga gccgagacta
    18121 ccgcttgaga atccctgaaa gtaatcttcc ggcaatctct ttaagaaaaa gtgtggacaa
    18181 aaatgttatc aatctcaatg aaaatgaact aacgtatact ctgcatgtct cgatgttttc
    18241 tggaacaaga aatacgcttg ttattgaaga tgttttggaa gaaggcatgg aatttgtgtc
    18301 atttctatca gatattccct ctttcattga tgccgaagtc aataatggaa tagttcgttt
    18361 cagtgcgaat aatacgattg gtggtccgac aagttttacc ctctctttta aggtcaatgt
    18421 agaggcgtat gcggtcggcg atcaaatttt aaactttgca acgcttgtga atagtgacaa
    18481 tcgattgaat acgagtactg taagaacaag gaaaatcgat gggcgtatta aagtaattaa
    18541 aactgatgag aatggccaaa ggctggcagg agcaaaattt gaaattttat caagcgattc
    18601 acaagtgata caagaaggta taacggcaga aaacggagaa tttttaagtg aaccgcttcc
    18661 tgtaggtagc tatcaagtcc gagaaacaga agcaccggaa gggtatcttt tagatgcgac
    18721 ggtacatgat gtttttataa atgaatactc catagaagaa gtgacgttaa ccattgaaaa
    18781 catccttgat acgggtggtg ttgaactaat taaacatgct gaaggcagtg gtgaagtcct
    18841 tcaaggagct gtttttgagt tacagaaccg agaaggagaa acgctacaaa ccggt
//
LOCUS       DACBZK010000052        18559 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.054, whole genome shotgun sequence.
ACCESSION   DACBZK010000052 DACBZK010000000
VERSION     DACBZK010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18559
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.054"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            6..305
                     /locus_tag="IVD66_001916"
     CDS             6..305
                     /locus_tag="IVD66_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6146120.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="IVD66_001917"
     CDS             378..1739
                     /locus_tag="IVD66_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAP6146121.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="IVD66_001918"
     CDS             1761..2021
                     /locus_tag="IVD66_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146122.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="IVD66_001919"
     CDS             2035..2787
                     /locus_tag="IVD66_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HAP6146123.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="IVD66_001920"
     CDS             complement(2881..3486)
                     /locus_tag="IVD66_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP6146124.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="IVD66_001921"
     CDS             complement(3539..4513)
                     /locus_tag="IVD66_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HAP6146125.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5670)
                     /locus_tag="IVD66_001922"
     CDS             complement(4891..5670)
                     /locus_tag="IVD66_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6146126.1"
                     /translation="MLLRVVGSIIFRYTLEEVNNVPKYEEIANILRERIRSKEYPLDS
                     FLPNQVDLVKEFGASRMTIKKAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEY
                     EGLSLQMKRRHRSLKSQIIHFDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVL
                     EHTFMPVHLVPGLKKEHLLASIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAE
                     NDPVLEVQQVVYLKDGQPIEYSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="IVD66_001923"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="IVD66_001923"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAP6146127.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="IVD66_001924"
     CDS             7161..8558
                     /locus_tag="IVD66_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP6146128.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="IVD66_001925"
     CDS             8639..9079
                     /locus_tag="IVD66_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP6146129.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="IVD66_001926"
     CDS             9227..9553
                     /locus_tag="IVD66_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP6146130.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="IVD66_001927"
     CDS             9554..10303
                     /locus_tag="IVD66_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146131.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="IVD66_001928"
     CDS             complement(10383..10838)
                     /locus_tag="IVD66_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAP6146132.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="IVD66_001929"
     CDS             complement(11265..11540)
                     /locus_tag="IVD66_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146133.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="IVD66_001930"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="IVD66_001930"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HAP6146134.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="IVD66_001931"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="IVD66_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAP6146135.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="IVD66_001932"
     CDS             14770..17436
                     /locus_tag="IVD66_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP6146136.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="IVD66_001933"
     CDS             17800..18552
                     /locus_tag="IVD66_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP6146137.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
BASE COUNT         5965 a         3212 c         3831 g         5551 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttc
//
LOCUS       DACBZK010000053        18238 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.055, whole genome shotgun sequence.
ACCESSION   DACBZK010000053 DACBZK010000000
VERSION     DACBZK010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18238
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.055"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            258..743
                     /locus_tag="IVD66_001934"
     CDS             258..743
                     /locus_tag="IVD66_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HAP6146138.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            736..1419
                     /locus_tag="IVD66_001935"
     CDS             736..1419
                     /locus_tag="IVD66_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HAP6146139.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            1545..4190
                     /gene="polA"
                     /locus_tag="IVD66_001936"
     CDS             1545..4190
                     /gene="polA"
                     /locus_tag="IVD66_001936"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HAP6146140.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELADKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            4235..5071
                     /gene="mutM"
                     /locus_tag="IVD66_001937"
     CDS             4235..5071
                     /gene="mutM"
                     /locus_tag="IVD66_001937"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HAP6146141.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            5035..5664
                     /locus_tag="IVD66_001938"
     CDS             5035..5664
                     /locus_tag="IVD66_001938"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HAP6146142.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            5716..6048
                     /locus_tag="IVD66_001939"
     CDS             5716..6048
                     /locus_tag="IVD66_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAP6146143.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHISDEQKIEEQRMKH
                     YTGIEEKL"
     gene            6360..6851
                     /gene="nrdR"
                     /locus_tag="IVD66_001940"
     CDS             6360..6851
                     /gene="nrdR"
                     /locus_tag="IVD66_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HAP6146144.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            6874..8247
                     /locus_tag="IVD66_001941"
     CDS             6874..8247
                     /locus_tag="IVD66_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication initiation and membrane attachment"
                     /protein_id="HAP6146145.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            8247..9173
                     /gene="dnaI"
                     /locus_tag="IVD66_001942"
     CDS             8247..9173
                     /gene="dnaI"
                     /locus_tag="IVD66_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HAP6146146.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            9302..9742
                     /locus_tag="IVD66_001943"
     CDS             9302..9742
                     /locus_tag="IVD66_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAP6146147.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            9886..10587
                     /locus_tag="IVD66_001944"
     CDS             9886..10587
                     /locus_tag="IVD66_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HAP6146148.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            10584..11705
                     /locus_tag="IVD66_001945"
     CDS             10584..11705
                     /locus_tag="IVD66_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HAP6146149.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            11720..12952
                     /gene="pepT"
                     /locus_tag="IVD66_001946"
     CDS             11720..12952
                     /gene="pepT"
                     /locus_tag="IVD66_001946"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HAP6146150.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            13084..13992
                     /locus_tag="IVD66_001947"
     CDS             13084..13992
                     /locus_tag="IVD66_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HAP6146151.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            14027..14299
                     /locus_tag="IVD66_001948"
     CDS             14027..14299
                     /locus_tag="IVD66_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HAP6146152.1"
                     /translation="MDVLLHNLLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            14310..15356
                     /locus_tag="IVD66_001949"
     CDS             14310..15356
                     /locus_tag="IVD66_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HAP6146153.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            15607..18216
                     /gene="clpB"
                     /locus_tag="IVD66_001950"
     CDS             15607..18216
                     /gene="clpB"
                     /locus_tag="IVD66_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HAP6146154.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQPNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
BASE COUNT         6203 a         3169 c         3995 g         4871 t
ORIGIN      
        1 aaatcttgcc aagccccctt ttttgcaact tatgataaac ggtgttcaaa agcttgcatc
       61 tgcggtaata agcccaatca aatcaaaaac atgagaagct gttttttctt ggctgttctt
      121 attatttgat gcaggacagc tttttcacga cctctgtaaa ctataggaat ctgttaaatc
      181 aagggagcag aacttgcctt ttacgctact tttggtacaa taatgtatga ttaaaaataa
      241 actggagggt ttctatcttg aacataggta agccgagaaa actaggaaaa acaataaatg
      301 aaatcgagga aggcgactcg ttatccttaa cagaatctat tgaagataac cagcttttgc
      361 tgtatttggg attgacgaat gatgcaaatc ctttgtatat ccaacatgac tttgcacaaa
      421 aaacagaata tcaacagcca atcgttccat cagtgatgct gatggggatc atcacaagtg
      481 caatttcaaa gcatcttcct ggaccaggat cacatgttgt caatttttct gtcaatttta
      541 ttgaaccggt tttccattat gaaacactga cttttcagtt tgaggtcata aaagtagata
      601 agatgaagga tgtggtgacg atttctgtag aagcggagaa tacgaacgaa gatcgtgtgt
      661 tggatgctgt cgttatggtc caaccgccac aagttcctga attggaaata gcaatcgaaa
      721 gtgaaggtga attgaatgaa taatccaagt acatcaatgt caggtatcaa tcgtttttat
      781 gcaaaagttt atggattttt aggtatggga cttgccctta gtgcagtcac ttcttacttg
      841 gctctttggg tatttccttt gcaattagca acttttatca ataattttcc actaggcttt
      901 gtgggtctgt ggatcgttga actgatttta gtaatggttc taggcgtaaa agcacaaaag
      961 aatccgagct tagcaatcgg tggatttatt gcctactctc ttttgaatgg cataacatta
     1021 gcggttactc ttgcatacta cgatattgga acagtaacgc aagctttctt gacagctact
     1081 ttgatgttca tggggatgtc tgttgtcgga gtaacaacaa aaagagatct tagcggggtt
     1141 ggaagagcag gacaggcagc tttaatcgga gtgatcattg cactagtctt gaacatcttc
     1201 attttgagaa gtagcgtagt tgagctgttc atctccctac tgttagtcgt catctttgca
     1261 gggattacag cttatgataa ccaaagcatc cgtaatatct atgtccagac aaacggaaca
     1321 gcacatagtg gaattgctgt attcatggca ttgaagctgt atttggactt tatcaacttg
     1381 ttcttggcgt ttctgagaat ctttggacgg aacaactaaa aaagaaaaaa attcatcagt
     1441 tggggctata ccgaattatt tggtatggtc ccgctttttc ttttcgcatt ccgcaggatt
     1501 ctttgttaga atgaataaga actttacagt aaggagttaa gaagatgaca aaaaataaat
     1561 tattactcgt tgatgggaac agtgtggctt ttcgcgcatt ctttgcgctt cacaattctc
     1621 ttgaacgttt caaaaataga aacggtcttc atacaaatgc aatctatgca ttcaatacga
     1681 tgtttgaaaa tgttatgcaa aaagagcaac cgactcatgt tctggttgcg ttcgatgcag
     1741 gaaaaacgac ttttcggaca gaaatgtatg cggagtacaa aggtggaaga tccaaaacac
     1801 ctggcgaatt caaagaacaa atgccatata tacgtgattt gttgacagga ctaggggtac
     1861 agtattacga attgcccaat tatgaagcag atgatattat cggtactttg gcagaaaaag
     1921 tagacaaaga tcaatttgat gtcgtcgtgc tttcaggtga tcgggatttg actcaattag
     1981 ctagtaaaga agtaaaagtg gatatcactg taaaaggtgt cagcgatatc gaaagctata
     2041 caccagaaca tgtagcggaa aaatatgatg ggttgacgcc aaaacagatt attgacatga
     2101 agggactagc cggagatgcc tctgacaata tccccggtgt gactaaaatc ggtgaaaaaa
     2161 cagctatcaa gctattgaaa caatatggct cagtcgaagg aatttatgaa catatcgatg
     2221 aaatgaagca aagcaaaatg aaagaaaatc tgataaatga caaagagcag gctttcttat
     2281 cgaaaaaatt ggcgaccatc aatacttcag cgcctgtgga tgtctctatc gactcattga
     2341 agtatgaagg gaaaaatctc gataaactcg ttccgtttta taaagaaatg gatttcaatc
     2401 agttcctttc taaattgaat atcgtagaag aagaagtaaa aatggatgat attttgtttg
     2461 aagtcgttca tgaattcaaa gaggaaatgt ttactacgga tatggcgttg tacgtggaaa
     2521 tgatgggcga caattatcat acagaggaaa tcgtcggagt agcgtggggg acagaaaaga
     2581 aaatttatgt cacgaacgat ctatctgtat tcgaaaaccg agcgttccat tcttggatca
     2641 ctgatccgac tcggctgaaa aaagtatatg atgcgaaacg aacttatgtt gctttaaacc
     2701 gctatactgg aaaaacgaaa ggaatcgatt ttgatgtctt gctaggtgca taccttctcg
     2761 atacgaatga aaaaagcaca gatatcgaag gaatagctgc tcattacgga tacaacgata
     2821 tccaatcaga tgaagctgta tacggcaaag gggcgaaaaa aggtttacca gaagaagagg
     2881 aactcttttt tgctcattta gcgcgaaaag tagctgcaat caatgcgttg acaccaaaat
     2941 tgagccaaga actggcagat aaaaaccaag aagatctttt ccggaaaatg gaactgccat
     3001 tgtctatcat tttggcagag atggaaataa gcgggatcaa agtagatgcg actcgcttac
     3061 aagaaatgaa gggcgagttc tctgctcgct taagagagat cgaacaaaaa atctacgaag
     3121 aagccggcga agaattcaat ttgaattcac caaagcaatt aggagtgatc ttatttgaaa
     3181 aaatgggatt acccgttatc aaaaaaacaa aaactggata ttccacagcc gtagatgtac
     3241 tggaacagct tcgtgaacaa gcaccaatcg tagaggatat cctcacctat cgtcaaattg
     3301 caaaaattca atctacctat gtcgagggac tgctgaaagt gatccaatca gatggaaaag
     3361 tgcatacccg ttatgtccag acattgaccc aaacaggacg attaagctct gttgatccta
     3421 atttgcagaa catcccgatt cgattagatg aagggagaaa gatacgtcag gcatttgttc
     3481 ctagagaaaa agactggctg atttattctt ctgactattc acaaatcgag ttacgcgtac
     3541 ttgcgcatat ctcaaatgat gaacatttga aagctgcctt cctagaaggt caagatatcc
     3601 atgccagcac agcgatgcgt gtatttggaa tcgaaaaggc agaggatgtc acaccaaata
     3661 tgcgtaggca ggcaaaagca gtgaattttg gtatcgtgta tggcatctct gattacggac
     3721 tttcacaaaa tctaggaatc agccgaaaag cagcacagca atacatcgat acgtactttg
     3781 aaaaataccc aggtgtcaaa gaatatatgg aaagaatcgt acgcgaagca aaagaccaag
     3841 gctacgtcga aacgctgtat caccgccgtc gatatctgcc agacatcaat tcaagaaatt
     3901 acaatatccg ttcttttgcg gaacgaacag ctatcaatac accaatccaa ggaagtgctg
     3961 ctgatatttt gaaaatcgcg atgatcgaat tggataaacg attaaaagaa acaggtcttc
     4021 aagctacgat gctgttacaa gttcatgatg aacttgtctt cgaggtaccg gaaaaagaac
     4081 ttgaatcatt agataaattg gtgaaggaag ttatggaaca agctgtttct cttcatgtac
     4141 cactgatcac tgacagcagt tggggaaaaa cgtggtacga agcaaaataa acattgttta
     4201 agacagagca atataatgaa ggtgaaaaga aaaaatgcca gaattaccag aagtagaaac
     4261 cgttcgtaaa ggattggaac ggttagtagt aggaaaaacg attcaaaaag ttcaggtctt
     4321 gtggcccaag atcatcgagc aaccagagac acccatcttt gaggcttctc ttgttggcga
     4381 aaccatccaa tccattggac gtagagggaa gtttttaatt tttcatctcg atcattgtga
     4441 actgatctca cacttgcgaa tggaaggaaa atatcaattt acgaaagaaa atacaccaat
     4501 cgataaacat acgcatgtac ttttcttttt tgaggatgga agccaacttc gctacaacga
     4561 tgtacgaaaa tttggtcgta tgacaatcgt cgaaaaagga gcaagtgcaa cttaccgagg
     4621 aatcatgaaa ttgggacctg agcctttgcc agatagcttc ttattagcag atttcgcaaa
     4681 tggactgaaa aagtcccaca aagcaatcaa gccattgctg ctagaccaac gtctagtgac
     4741 tggtctaggt aatatttatg tagatgaagc attatgggaa gcgaagatcc atccagaaca
     4801 accggcgaac acactgcgcc ccaaagaggt agaacaatta cgtctatcga tcattgatgt
     4861 tttggatcgt gcaatagaag ccggaggtac cacgattcgc agttatttga atgcattagg
     4921 agaatcaggc ggatttcaag tagcactgca tgtctatcag caaactggca aaccatgtat
     4981 acgttgtgga acgccgatcg tgaaaacaaa agtggcacaa agggggacgc actattgtcc
     5041 gaattgtcaa aggctaaaaa tcgcaaagta ggatttgttt taggtttgac gggtggaata
     5101 gctaccggta aaagtacggc agccaaagtc tttcagtctc atggatttcc tttgatcgat
     5161 ggcgatgtga ttgccagaga aactgttgag cctggaacgc ttgctctgag gaaaattgta
     5221 tcagtgtttg gccaagaggt attgcagcct gatgggcaac tagatcgagg gaaacttggg
     5281 atgattgttt ttccatcaaa ggaaaaacgg caaaaacttg atcagctatt agatccgttt
     5341 atccgaaaag cgataaaaga tcaaatcgcc tctctaagtt ccaatcatcc tttagtaatt
     5401 gtagatatcc cattgctcta cgaaggtcat tatgaccact atatggatgc agtagctgtc
     5461 gtttatacta cgccagaaac tcagcttcag cgtttgatga aacgtaatca actgacgcta
     5521 gaacaagcgc agcagagaat tagtagtcaa cttccaatcg aagaaaaaaa gcagcgtgcg
     5581 gatattttgt tcgacaacaa tggaacaaaa gaaaaacttg tgggacaaat cgaaaattgg
     5641 ctttttgcta atcgctttct ttgagtatct gtgtcaattt tgctatcctg agtatataga
     5701 aagtgaggga tagcgatggg atcattaaaa aatcaaaagg ataaagtcgt aggtaacgca
     5761 aaagaaaaaa tcggcgagat gctcaataaa gaaaatctaa tcgatgaagg tcgtacgcaa
     5821 tcagaaacag cagaagaaaa agaaaagcag taccaagcaa gaatcgatga aatagaagac
     5881 cagcaggcag aagaagaagc gaagcggcaa gatttgactc aagaacgaaa aaatccgaca
     5941 cctgatcgta gtaaaacacc gctcccagaa agtgaccaca tttccgatga gcaaaaaatc
     6001 gaggaacagc gaatgaaaca ctatacagga atcgaagaga agttataaaa tagtaaaaaa
     6061 tcgagatgtg acttgaagca gatgagaagg tgttcatctg cttcaagttt tttgtgctag
     6121 atgactaaat cagcttttgt gtaagttatt tctcagtaat caaggtgatc agtattggaa
     6181 aattgaaatt tagtaaggac aggggacaca attacgcatg aaagtagaaa aaattgttct
     6241 tatatccgtg ttttttgggt aggacagtcg cgtttgtgat ttgtttcgtg ttataataca
     6301 actagttgta aagaaagaca catcctttat ataaaatgcg atgcaagagg tgagacaaaa
     6361 tgagatgtcc cagatgtcaa cataataatt cacgagtaat cgacagccgt caagcagatg
     6421 atggacgtgc gatccgtcgc cgtcgcgaat gtgagaattg ttcgttccga ttcactacat
     6481 ttgaacgaat tgaagctgct ccgttattag taatcaagaa aaacggggaa cgcgaagagt
     6541 tcaatcgcga taaaatttta agaggactca tccgttcagc agaaaaaaga cctgtagcta
     6601 tggaacaaat ggaacaaatc gtcaaccatg tcgaaaaccg cgtacgcagt ctcggagaaa
     6661 acgaagtatc gacgaatcta attggtgaat atgtgatgga agatttagtt gatttagacg
     6721 aaatcgctta tattcgtttt gcaagtgttt atcgccagtt caaagatatg tctgttttct
     6781 taaaagagtt gcaagatatc gtggataaag caaaagaaaa taataaagag aataataaag
     6841 aaaacaatta agaaacaaaa aggaggcatt tccttggaaa atgcttggaa agagcttcaa
     6901 ccaaaaaata tttaccaagg aagaaaagcg gctccgctga gagaagacag caagaacgcc
     6961 ttgctgtatc tttatcagcc actaatcggc ggagaagcct tgagtatcta tttcaccctg
     7021 ttatcagaaa tctctcaaga atctggcaaa ggtcctgaag ggatgcatgc agatctgctt
     7081 agtagtctag gctgcggtat cccgcaattt tatgatgcaa gaaaaaagct agaaggaatc
     7141 ggcttactgg atgtttattt taaagaagat agtgatctgg gacctcgttt tatttatgag
     7201 ctgttagaac cactcattcc taaagcattt ttcaaagact ctgttctggc ttttcttctt
     7261 ctggaaaaag ttggtgaacg acgattccag aagcttaccc aattctttga acctaaaagg
     7321 catacagcag agggatatca aaaaatcaca aaaaaatttt tagatgttta tcgcttcaat
     7381 gaagcagtgt acgctgctaa tcaagaaaac atcgaatcgc tgaataaatc ttttgaagaa
     7441 tctgaatcag tagcattact tgaagcagat tcgacattcg attggcagtt tttgaatgat
     7501 tggctggcaa aaaaacatat tgcaagtctt gatgatccaa tcatcaaaca agtcgacatg
     7561 tatcatcagc tttacggttt cgatgaattg acacttggcg aactgatcag tcaatcttat
     7621 gactttagtg aacaaaaagt atctgaaaaa gaactgcaaa aagccatttt ggcaatgcag
     7681 agacgtccgg tgaagcaaac aaaagaaaca gttgcggttt ctgaaaacag taatgaaccc
     7741 tcgtcaaacg aacatttgac aaacgcagcg cttcagctga taaaagaagc acagagcatt
     7801 ccaccgatga aatatctgga agcaatcaag tcagaaaaag gcggatatgt ttctaaacaa
     7861 gaaaactggt tactgcaaga tcttgtttct caatcaggtc tttccagtag cgtgatcaat
     7921 gttttgctga attatgtact agtgatcaag aataatgcta gcttaaatgc cagttatgta
     7981 aatacagtgg caaatgaatg ggcacaaaag aaaatcgcca cagcagaaga agcgatccag
     8041 cacattcggc aaataagtaa tcaagcaaaa caatcaaaac aaaagaagca aacaaattat
     8101 caaactggca agcgaaatgt tcgacgggaa aagcttcctg attgggtcaa ccagccaaaa
     8161 gatgaaaaac agatcagcag cgagaaaaaa gcagagattg accgccgttt taaagaatac
     8221 ctggcaaaaa aggagggtga tatctagtgg aagacgtagg caaagaattg aagaggatca
     8281 tcagcaaacg caattatcaa gaaaagtatg ctgaaatgat cgctgaagtc ttaaatgatg
     8341 cggatgttca agcttttcta agcgcacacc aagaagaatt gacacaagcg gatattgaaa
     8401 aaagttacgc taaattgtat gaattcgtgc aagaaaagcg taaatatcaa aaaaacgatc
     8461 caacgatgat cgctcccggc tatgagccga agctgacgtt gaattttcat tatgtggatg
     8521 tcacttatgt accaacggaa gcattgttag cacggcaaag acaagaagaa atcagaagcc
     8581 gagtaaaagc aatggatatg ccaaaagata ttcaatcggc ttcttttgaa aactttgaac
     8641 gtacagatgg acgaggatat gcgagcttag aagccctaga ttttgtagag aaatatactg
     8701 ctgatccaaa agggtatcat aaaggactgt atctagtagg aagttttggt attggaaaaa
     8761 catatttatt aggagcaaca gcgagagaat tagcgattgc tggattcacc acgacgctag
     8821 tccattttcc gacatttgcc gttgagatga aacaggcaat cggaaaagat caagtggcag
     8881 aaaagttaga tgcagtgaaa cgttcaccta ttttgatgat cgatgacatt ggtgcagatg
     8941 cgatgagtag ttggatacga gacgaagtat tcggtgttat ccttcaatat cggatgcagg
     9001 aacagttacc aaccttcttc tcatcgaatt ttacaatgga tgaattggaa cagcatttgt
     9061 ccgtcactca acgtggagat gaagagccgc taaaagcgaa acggataatg gaacgcatac
     9121 gttatttgac aaaagaaatc gaaatgactg gtcgcaaccg acgcaatggt tgaacagttg
     9181 acaagtccaa ctgacatttg acctagtagt aaaagcaggt cagcgaatca ttatatggac
     9241 agaaatgacc ggagacaatc accgcaacaa gtaatgcaga aacttaaacg gaggattttt
     9301 tatgagggct attttttcta gtatatctgt agttggtcta ttttttcttt tagcaggctg
     9361 cggtagcgca gatagcaaca caggttctgt tgattcgatt gatgcgggtc aaacagtaaa
     9421 aacaagcagt acgaaaacgg agagacaaag catatttgtc ggaacgattg aaagtattac
     9481 tcaagtagaa gcagaagaag aaacgcttca gttgaaactc gtcgatgtca tggccaaaga
     9541 agatccagcg aatatgggaa cgtcattcag caatgacgga gtgatcttaa atgctactgc
     9601 tgaaaaaata agcgtggaca taaatgaatt gaaaatcggt gacaaagtcc aatttacatt
     9661 agttgagatg ccgatcatga cgatgtctat cccaccgcaa gttcctggag attcgattat
     9721 tgatgtttca ttgaacaaat aaccaataac attttttcaa aaataagaaa atgttgtttt
     9781 atagaacgaa aaggtatatt ttttaaggag atatgggaat ttttttattc ctagtctcct
     9841 tattttattt ggaaaatgct ataattatct agaaggagtg aagctatgaa ccatttagat
     9901 ttatctcagc gcttagccgc agtgggtgac tttgtccctg aatccgctcg tttagcagac
     9961 attggatcag atcacgctta cttacccgtt gcattgatat taagaggaaa aatcgaatat
    10021 gcagttgctg gtgaagtcgt tcaaggtcct tatgaatcag cacgtaagca agtcaaaaaa
    10081 gatggattag aagaccgtat caccgtacgc cttgcaaatg gtctagatgc tatccagcca
    10141 caagatggta ttacagctgt cacgattgcg ggtatgggag gttcactgat ccgagatatc
    10201 ctagaagctg gcaagttgaa tcaacgctta agcggacaag aacgtttgat ccttcagcca
    10261 aacatcggag agcgtacatt acgatcttgg ctgcaagaaa atcagtataa aatccaatca
    10321 gaaaaaatac ttgaagaaaa taaaaaaata tatgaaatca ttgtagccga aaaagaacaa
    10381 aaaccagtta cttacaatga aatggagctg atgttcgggc catttctgct tgaagagaaa
    10441 agtgagatct tcaaatcaaa atggacaaga gagcttcaac aaagaaaagc tatccgtgaa
    10501 cagctcaaac aagcagctaa tcaagaggca cgtcaaaaac aaatcgagca ggaaatccaa
    10561 atgattgagg aggttttaaa gccatgacaa tcagcggacg cactttcatc caaaagtttg
    10621 aaagctattg tcctcagtgg ctagctgaag aaggagaccc agtcggactg catatcggaa
    10681 cattggataa gccaatccaa cgagtaatga tgacattaga cgttcgtcca gaagtggtcg
    10741 aagaagcaat caagaaaaaa atcgatttgc tgattgctaa acatcctcca atctttcgtc
    10801 ctgtaaaacg gctggttact gatcagccac aagaaaaaat gtatgcagat ttgttgaaac
    10861 atgatattgc cgtctatgca gcacacacga acatggatat tatttgggat ggactgaatg
    10921 actggttttg tgaacttctc ggtattgaag tggagagtta tttagtaaag actcatgaga
    10981 ttcattataa aaaactggcc gtttatgtac ctgtggatca tgcacagaaa atgcgtgaag
    11041 tattagctgc agctggtgct ggtacacaag gtgattatac cggtacaagt tttacctcga
    11101 ttggacacgg tcgatttact ccggaagctg gtgcacaacc agcgattggg aaagtaggga
    11161 agacagaaca agttcaagag gcaaaagttg aggttatttt gccggaaact atcgaaaaac
    11221 aagtgattca agccatgcgg tcagctcatc cttatgagga acctgcttat gatcttttcg
    11281 ctatagatga accagtcgaa atgtttgggt taggacgagt aggtgaattg ccgcaagaaa
    11341 tttctataga ggcatttgta gaacaagtaa aagaagcgtt ccaactagat ggactgagaa
    11401 tagtccagcc aaaaaatgca aaatcctctg tgaagcgcat tgcgatttgc ggtggaagcg
    11461 gtgaaaaatt ttatccgcaa gcaatcgccc aaagagcaga tgtctatatc acgggagata
    11521 tctattatca tacggctcat gatatgcaaa gcgctgggtt gattgcaatt gatcccggtc
    11581 attatattga atcgttatgc aagcaacgat ttatcgagaa atttgaatct tggaaacaag
    11641 aagaaaattg ggatattaac tttttcgttt ctgaaacaaa tacaaaccca tttcaattta
    11701 attaaaagga gagaatacta tgtacgaaaa tcttttgcca cgttttttac gatatgtcaa
    11761 aacagaaaca cgctccgatg caacaagcaa aacgactcca tcgactcaga cacaagttgc
    11821 ttttgcgcaa gaattgaaaa aagaattaga agagttaggc ttagctgatg ttttctataa
    11881 tgaagataac ggattcgtta tgggaacatt accaagcaat gttgatcatg aagtgcgttc
    11941 cattggattt atttcccaca tggatacagc agattttaat gcagtaggag tcaatccaca
    12001 aatcattgaa aactatgatg gcgagtctac gatcgtacta gatgcggaag aacgctatac
    12061 attgaataca aaagattttc caaatttgaa aaattatgaa ggccacacat tgatcacaac
    12121 agatggcagt acattactgg gagcagatga caaatcaggg attgcggaaa tcatgactgc
    12181 aatggagatc ttgatcaata atccttctat ccctcacggt accatcaaag tggcttttgg
    12241 tcctgatgaa gaaatcggtg tcggagcgga taaattcgat gttgagcaat tcgatgtaga
    12301 ttttgcttat acagtcgatg gtggtccttt aggtgagttg cagtatgaaa cgtttagtgc
    12361 tgctcaagca aatattacga tccaagggaa aaatgtacat ccagggacgg caaaagatac
    12421 aatgatcaat gctctacagt tagcaatcga ttttcataat cagcttccag ccgatgaagt
    12481 tccagaaaaa acggaaggat acgaaggttt cttccatttg atggcattgg atgggaatcc
    12541 tgaagaagct tctatgagtt atatcattcg cgatcatgat cgtgaaaaat tcgaagcacg
    12601 caaagcacaa atcacacata tccaagaaga gttgaatcag cgatttgatc aagaacgaat
    12661 caaagtagat atgtatgatc aatattacaa catgaaagaa atcattgaaa aagatatgag
    12721 catcgtggaa ttagcgaaac aagcaatgat cgagcttggt atctctccag tgatcgaacc
    12781 agttcgtgga ggaacagatg gttcaaaaat ctcttacatg ggtattccga cgccaaatct
    12841 atttgccgga ggagaaaata tgcacggacg attcgaattt gtttctttac aagtaatgga
    12901 aaaagcaaca gacgtgattg taaaaattgc agaattgaac acaaagagtt aaaatcgaaa
    12961 aagaacagct tatgacaagg cgttcgtccc aatgatggaa tgtcatctgt ctaaggctaa
    13021 agggcaggac aatggaattg gttgtcccgc cctctttttt gaagagtaaa taggaggtaa
    13081 agaatggaaa agctgctagt tttttataac aaaagttcag ggaaagatga gggtgagaaa
    13141 ttagcacgct ggtttcaaga ttatgtaaaa gaaaagcagc cagaattata tgtagaacta
    13201 gctgaaactg gcccatcgat tgatgatgcg gaattagtca agaaagcaga agccatagaa
    13261 gctgatactt tagtaattat aggtggagac ggcacgattc atcatatcgt ccaagcgttc
    13321 caaaaaacat tatctcaata ccatgtcgga ttacttccag gtggaactgt caacaacctt
    13381 gcacgtgttc ttgagattcc cctcaaaaaa gaagaagctg ctgacgtgat cctggaaggc
    13441 aatgtacgga aaatagacta tggtcaagtc aatgatgaag tcattatctc tacactgaca
    13501 atcggaatct tagcagatac agcagtttgg atcagtcaag aagaaaaaca gcgttacggc
    13561 tcgtggatct ttatcaagaa gttttttaag ttattgctga agaagaaaaa atatcatttg
    13621 gatttagaaa cagacgagga gcattggaaa ggaaaatccc aactgttgac agtcacgatg
    13681 tctaactccg tgggcggttt tacaaatttt gacgactcag cgaccctaga tgatggaaaa
    13741 tttcatgtaa cgatcgtacc ttccttagat attttccgat ttatttttta tttgcctaga
    13801 atcatgagag gcaaattcta tacgatcccc ggcattactt atttcacagc caaacgcatg
    13861 aaaatccaag cgcaggaaaa atctgtgggc actcgaacgg atggagacac gacagatgat
    13921 cttccagttg aattatctgt tgtatcaaaa ggattaacag tttattcacc aaagaaagaa
    13981 gaaaaagctt agaaatagta gttaacagaa agttggaaga agagtaatgg atgtattgtt
    14041 acacaatctt ttgtggtttt accttttcat tgtgaatttt tacttatttt gtctgatggg
    14101 gtatgataaa catcaggcta gaactagcgg ctggcgtgtt cctgagaata atttgatatt
    14161 tgtcagcctg ttaggcggtg gtttgggagg attgatctct cgaaaagttt tccatcataa
    14221 aactcggaaa aagaagttta ctataggatt cgctgcaggt gtacttgttg atttgattct
    14281 catttatttt ttccattaag gagcaggaga tgtcgtctaa aggaacgaaa actaaaatca
    14341 ttctgaatct gcttttgctg attgtgattt ttgccattat ttattattta atcaatcaat
    14401 catttgcaga tatctttgcc gaattgctgt ctaccagtgt tgttgttttg gcagcggctg
    14461 ttatattagg gacagtttac caaatcgctg aagggcgctc aatcaaagaa attgctgaac
    14521 ctttcgcgcc gaattttaca acgaaagatg ggttcttgac ctctagctat attgcgtttt
    14581 accgaatcgt ttcgtttggt acaggaacgc tgatctcgga gatttatttt tataacaaaa
    14641 aaggaatgaa gctatcccag ggagcagggg tgacagcact ccatatgatt atgtacaaac
    14701 tggcagtgat cacttatgca ttagctggct tggtcatcca attctctctt ttttattcta
    14761 atggtccatc aatgatctgg tttatcatcg ctggtatcct tttgacgatc gtgattgttg
    14821 cctttttatt ggcgatgtcc gtcagcttga atgttcaaat attttttgtc agcttatcga
    14881 ataagttatt taaaagtgag cgtttgcgga aatgggtgga tacatgcaat cagcagatct
    14941 actctttaag ggaaacggtc caaaccatta tccaagacag gactgcgcta ttgcggattt
    15001 atctatggaa tatgttaaaa cttgtatttt ggtatgtact tccttatttg attctgattg
    15061 aaaaccatcc taaaatagat tttctactga ccatttcgtt tatcagcttt gcagtagtgc
    15121 tttcaggggt tattcctacg cctgctggta ttggttcctt tgaatttgtc tatttgttat
    15181 tattcagacc agttgttgga acagttgacg cagtttcttc gcttttactg tatcgtttca
    15241 gttcctttat cttgccattt ctctatggat ttgtgtatgt gattgctgaa cggcgaagag
    15301 tgatcaaaga agaaataata gaagtaaaaa aagagaataa agaaaatcaa gggtaggtct
    15361 tttataagat ctaccctttt tatcaaatca aagaaaaacg ttatggataa gataatttta
    15421 cgtttgtttg gctctttttt tatatacata caatcaattt tgttttttta agatttatat
    15481 aagtcgagaa aaaaagtcaa aaaaccatgt gtatattttg accaaaattg accaaagcga
    15541 tataatagtt tttgtaaaga tcaaagaaat aagtgatctt acctttaatt aggagggtat
    15601 acctgtatga atattgagaa aatgactacg acgcttcaag aagcgattgc tgaagctcaa
    15661 cagattgcgg tcactcgaaa acatcaagat atcgacattg cccatgtatg gaaaatcttt
    15721 ttacaaccta atcattttgg tcgaaatttc tatacggatg ccggattgga tgtcgaatct
    15781 tttgaacatg aaattgatcg tctactggat gagtatccag ttgtttctgg tggaaacgtc
    15841 caatatggac aaaacctcag ccagaatttc tttcgattat tgaatgaagc agaccaaata
    15901 cgtgaaagct tcggcgacga gtttctttca acggaagtcg ttattttagc gttgatgaaa
    15961 ttaaaaaatt atccgttaac tgtttatttg aataaaaacg gattatctga aaaagaattg
    16021 cgtaaaaaca tcgaagagat gagaggagga gaaagagtga cctcacaaaa ccaagaagaa
    16081 caatacaaag cattagaaaa atacggcgtt gatttagtac agcaagtcaa aagcggaaaa
    16141 atggatccaa tcatcggtcg tgatgaagaa atccgtgatg tcatccgtat tctttcacga
    16201 aaaacaaaaa ataatcctgt tctgatagga gaacccggtg tagggaaaac ggcaatcgtt
    16261 gaagggcttg ctcaacgtat cgtacgcaaa gatgtgcctg aaaatttaaa agataaaacg
    16321 attttttcat tagatatggg tgcattgatc gctggagcaa aattccgtgg tgaatttgaa
    16381 gaaagactaa aagcagtctt gaaagaagtc aaaaaaagtg atggacgtat cctcttgttc
    16441 atcgatgaaa tccacaatat cgtaggggca ggaaaaacag aaggaagtat ggatgccgga
    16501 aatctgttga aaccaatgct tgctcgcggt gaattacatt tgatcggtgc cacaacttta
    16561 gatgagtacc gtcaatatat ggaaaaagac aaagcgttgg aacgtcgctt tcaaaaggta
    16621 ttagtcaaag aaccaacagt ggaagatacg atcagtattc tgcgtggatt aaaagaacgt
    16681 tttgagatcc accatggtgt taacatccat gacaacgcat tagtagcagc agctacttta
    16741 tctgaccgtt atattactga tcggttctta ccggacaaag caatcgattt gatcgatgaa
    16801 gccagtgcaa cgattcgggt agaaatgaac tctatgccaa cggaattaga tcaagttact
    16861 agacgtttga tgcagttgga aatcgaagaa gctgcactga aaaaagaatc agatgatgca
    16921 agtaaaaaac gcttgaaaaa tttgcaagaa gaattagctg aacttcgtga agaagcaaat
    16981 gcgatgaaga tgcagtggga aacagaaaaa gaagaagtca attctgtttc agcaaaacgt
    17041 gctgaaatcg ataaagcaaa acacgaatta gaagatgcag aaaataacta tgatttagaa
    17101 cgcgctgctg tattgcgtca tggtacgata cctcaattag aaaaagaatt gaaggaatta
    17161 gaagctaaag caaaagacag cgagattaag atggttcaag agtccgttac cgaaaatgag
    17221 attgctcaag tcgttggcag attaacgggt atccccgtaa cgaaacttgt agaaggtgaa
    17281 cgagaaaaac taattaaatt gaatgaaaca cttcataaac gagtgattgg tcaagatgaa
    17341 gcagttgatg cggtcagtga cgcggtaatt cgttcacggg ctggattgca agacccaaat
    17401 cgtcctctag gttctttcct tttcctagga ccaactggtg tcggaaaaac cgaattagcg
    17461 aaagcgttag ctgagaactt gtttgactca gaagatcata tggtacggat cgatatgagt
    17521 gaatatatgg aaaaacatgc tgtgtctcgt ctagtcggag ctcctccagg ctatgtaggt
    17581 tacgaagaag gtggtcaatt aacggaagct gtcagacgaa atccttatac aatcgtcttg
    17641 ttggatgaaa tcgaaaaagc gcatcccgat gtcttcaata tcttgttaca agtcctagat
    17701 gacggacgct tgactgattc aaaagggcga gtagtagatt tcaaaaatac ggttctgatc
    17761 atgaccagca atatcggttc acagttactg ctggaaggcg tgactgctga tggaacgatt
    17821 ccagaagcag tggctgaaca agtcaacacg ctattacgtg gaaacttcaa accagaattc
    17881 ttgaaccgaa tcgacgacac gattttattt acaccattga gcctagacaa cgtgaaagga
    17941 atcgttgaca aaatggtggc gcaattggca caacgtctgg aacatcaaga aatcctgctg
    18001 acaatcagtg atgaagccaa aacgtggatt gctgaaaatg cttatgaacc agcatatggt
    18061 gcaagaccat tgaaacgatt tatcactaag gaagtagaaa caccactagc taaagaaatc
    18121 gttgcaggac atgttatgcc taaatcaaaa gtaacgatta ctttacttga tggacaactt
    18181 catttcaaaa cagaagagct agaagaaatc gtctaatctt ccattgagac tataaaag
//
LOCUS       DACBZK010000054        18173 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.056, whole genome shotgun sequence.
ACCESSION   DACBZK010000054 DACBZK010000000
VERSION     DACBZK010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.056"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(26..394)
                     /locus_tag="IVD66_001951"
     CDS             complement(26..394)
                     /locus_tag="IVD66_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HAP6146155.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            565..1521
                     /locus_tag="IVD66_001952"
     CDS             565..1521
                     /locus_tag="IVD66_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAP6146156.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            1594..1710
                     /locus_tag="IVD66_001953"
     CDS             1594..1710
                     /locus_tag="IVD66_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HAP6146157.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(1765..3447)
                     /gene="recN"
                     /locus_tag="IVD66_001954"
     CDS             complement(1765..3447)
                     /gene="recN"
                     /locus_tag="IVD66_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HAP6146158.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(3465..3914)
                     /locus_tag="IVD66_001955"
     CDS             complement(3465..3914)
                     /locus_tag="IVD66_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAP6146159.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            complement(4021..4839)
                     /locus_tag="IVD66_001956"
     CDS             complement(4021..4839)
                     /locus_tag="IVD66_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HAP6146160.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            complement(4848..5738)
                     /locus_tag="IVD66_001957"
     CDS             complement(4848..5738)
                     /locus_tag="IVD66_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAP6146161.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            complement(5740..5964)
                     /locus_tag="IVD66_001958"
     CDS             complement(5740..5964)
                     /locus_tag="IVD66_001958"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HAP6146162.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            complement(5969..7306)
                     /locus_tag="IVD66_001959"
     CDS             complement(5969..7306)
                     /locus_tag="IVD66_001959"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HAP6146163.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            complement(7307..8161)
                     /locus_tag="IVD66_001960"
     CDS             complement(7307..8161)
                     /locus_tag="IVD66_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HAP6146164.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            complement(8258..8707)
                     /gene="nusB"
                     /locus_tag="IVD66_001961"
     CDS             complement(8258..8707)
                     /gene="nusB"
                     /locus_tag="IVD66_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HAP6146165.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            complement(8700..9125)
                     /locus_tag="IVD66_001962"
     CDS             complement(8700..9125)
                     /locus_tag="IVD66_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP6146166.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            complement(9371..10435)
                     /locus_tag="IVD66_001963"
     CDS             complement(9371..10435)
                     /locus_tag="IVD66_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAP6146167.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            complement(10607..10852)
                     /locus_tag="IVD66_001964"
     CDS             complement(10607..10852)
                     /locus_tag="IVD66_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP6146168.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            complement(10991..11365)
                     /locus_tag="IVD66_001965"
     CDS             complement(10991..11365)
                     /locus_tag="IVD66_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HAP6146169.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            complement(11448..12362)
                     /locus_tag="IVD66_001966"
     CDS             complement(11448..12362)
                     /locus_tag="IVD66_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HAP6146170.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            complement(12383..13186)
                     /locus_tag="IVD66_001967"
     CDS             complement(12383..13186)
                     /locus_tag="IVD66_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HAP6146171.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            complement(13219..14208)
                     /gene="manX"
                     /locus_tag="IVD66_001968"
     CDS             complement(13219..14208)
                     /gene="manX"
                     /locus_tag="IVD66_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HAP6146172.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            complement(14311..14802)
                     /locus_tag="IVD66_001969"
     CDS             complement(14311..14802)
                     /locus_tag="IVD66_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIB"
                     /protein_id="HAP6146173.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            complement(14993..17827)
                     /locus_tag="IVD66_001970"
     CDS             complement(14993..17827)
                     /locus_tag="IVD66_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6146174.1"
                     /translation="MAKRIDRIYMYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNS
                     SKDLNQLVREGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDT
                     KDIFAKIIGANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAH
                     HVIDEETELIVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLD
                     EIHRLPPEGQEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRI
                     PINIKLPAFEKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQL
                     KSNIQLVCARGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKIT
                     VAPNDTIMKIQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFY
                     KDHGFSFNADSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKK
                     INLGEERHTNDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLR
                     ANQASGRIGVVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNV
                     QEVDEGSGVILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDL
                     DMLHESLKNFRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNK
                     RQETELEVLALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVI
                     LDQLLMESELEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTT
                     GIGDEEYGFKINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLED
                     QIKVKVPIEEMYYLLRLVHNQLDKKEYTVP"
BASE COUNT         5218 a         4008 c         2991 g         5956 t
ORIGIN      
        1 actttttaca gcttttctat ttttttcata ggtaagaaag tatgttcaca atgatcaaga
       61 cagcgtacaa gacgattgtc aacagaaaaa ccaaacgcca agtcatcttg aaataacgcg
      121 gataaataat ttcttcataa taatatgctt ggaaaacagc aatacaaatt cccattagca
      181 aaacagaaat aaagaaaaac ggtaagatag aaattgtccc tgtatttcta gacaatgcat
      241 gcataccgcc ccacaaaaaa ggaatcgcca aatcaggggc ttttatttta aaacgacgat
      301 ttaacgaaaa taattttaca agaaattggc aaccaaacaa aacgattacc gggtaaatat
      361 accaaaacaa gataagtggt gtgaatgtgc ccatgaacgt aaactccttt tttatcgttg
      421 cttcaagtat actgtatata ctttacacaa ctgtttcatt ttatttaaat ttatgcagtt
      481 atattctata tcttacaaac acattccatg tattccaatt ccctatccgt tataataaaa
      541 gaaacaggca acaggaggaa aatcatgatc aaatatttta cattagataa tgagaaactg
      601 cgtaataccg gaaaggaaac tgaccaaacg atctggtatt gtgtagaacg tcctaatcaa
      661 gaagagattc atcagctgac acatcaattt gaaattccgt cagattacat cacttccata
      721 ttggacgatg cagaaaattc ccgtacagaa gaattcaatc aatcaaagtt gacaaagcca
      781 gcgttattat tgttacaata tccttttgct aaaacaagtc ctagcggtta ttttcaagtg
      841 gatacatacc cgctctctat tattttgacg cccaaaaaga agcttatcac aattacgaat
      901 catgaaccac tgtttttaaa gaaagtcttt agccagacct ttccaaaaag tgatatttcg
      961 cctaatctca atatcttctt tcaattcatt tggcaggtca cactctctta caacagttat
     1021 ttagctacgc ttcaatctca atgcgatact ttggaagcca aacttcaagt atccactgaa
     1081 aacaaacaac tttatcaaat catggatatc caaaaaagcc tcgtttattt cagagaagcg
     1141 acttctgcta atttagatgc attgaaagaa ctagcgcaaa ataaactttt ccaagaaaat
     1201 catgctttga aaaatcattt acgtgatgta ttggtggaaa cagagcaggc aatgactact
     1261 tctcgcattc aattaaaact agtagaacaa atgaatcaga ctttttcagc aatcgtatcg
     1321 aataatctga ataatattat gaaaatttta acttctttaa cgattatttt aactataccg
     1381 acaatcgtcg gcagtatcta tggaatgaac attaagttac ctattgctga aagggatgat
     1441 gcctttatat ggctagttct attaacatta tttatttgta tcgtaactac ctattattta
     1501 aaaaaaggga agtttttata aaaaagccct cttgtggaaa tggaaaaaag attgtacact
     1561 tgaatcaact aattaatgac gaggttgaaa acaatgcgtg aaaaaaaaca aacaagtact
     1621 tttgctaaag taacaaaatt tgtcatttgg acaatgctga ttttaacgat tggatctgtt
     1681 gtattgactg ctgtaatgag tgtcatgtaa aaataaaata tagctatcag ctgctgaaaa
     1741 ggacctgaac cactgcgagg tggctcaggt cctttttgcg agtttcaata gttcttttgc
     1801 atgttcgagt gtgagttttg taatctcact tccagccagc atacgtgcaa tttcttcttc
     1861 tctttctttt gttttcaact ctgaaacaga agtttgcgta cgtccatcaa tcactgcttt
     1921 cacaatataa tattgatagt cggcgactgc agcaacttga ggcagatgag tgatgcacaa
     1981 aacttgagag tatttcgata tttgagaaat tttatctgcg atggcctgtg caactcttcc
     2041 gctcacacct gtatccactt catcaaaaat aatacttgtc acaccttgct cagaagaaaa
     2101 aatagttttc aaagcaagca acatccgaga cagttcgcca ccagaagcga ctttcaccaa
     2161 aggcttcagt ggctctcctg gattggtcgt aatgtaaaat tcgatttggt caaatccatc
     2221 atgattcaat tgtctatttt cttcttttaa gaaacgtacc tcaaactcag tgttttccat
     2281 atacagactt ttcaattcat gcagaatgga tttttccaat tcttttgcga tttttttacg
     2341 cgcttcatga agatctgcgg cttgttgctg aagtagaagc tctttttgct ctagttcctc
     2401 tttcattttg tccaattgac cttctgaaaa atcagaagaa gctagctctt cggtgatttc
     2461 gtcatagtaa gccaatattg actcaatgga ttcgccgtat ttacgtttca actgtcggat
     2521 taattctaaa cgttgcgtaa cttcttctaa acgactctca tctaactcca ataaatcaat
     2581 ctgacgactc atatcgccga ttgcatcttg cagcaaatag taagcacttt ggatattttc
     2641 ataaattgct tcatactcca catctagatg ggcgatccct tgcagttctg aaacggccaa
     2701 gccaacacca tctacactgt tttgttcatt attcgtcagt gctccgtaac ctgcagctaa
     2761 tccatcagca attttttgat aattgctaag tttttctctt tcttctttta atttctcttc
     2821 ttctccgact tgcaaatcag cagcagctat ttcttcttgc tggaaatgga gcatatctat
     2881 tctctgaaca taggattttt cattttgctg cacttttcgt accctttttt ccagctcacg
     2941 ataagagata tattcttgct gataactctt tttcttctgt tggaaagcta catctccaaa
     3001 acgatccaat aaagcaagat gtgattcagg ctggagcagt tcctgatgtt cgttttgtcc
     3061 ttggatatct actaaataac tgccgattct tctcagatta gctaatgtga taatatgacc
     3121 attcactcga caaacatttt ttccagttaa ggacatatcc cgtcgaacaa tcagattgtc
     3181 ctcatctgtt tcgatcccta attcaaccat cagttcagag aatccttctt gttttggtag
     3241 ttcaaacaac ccttcaagca cacatttttc tgctccttga cgtatataat cgcttgaacc
     3301 tcttcctcct gctaacagac ctaaagcatc gataataatg gatttacccg caccagtctc
     3361 tccggtcagc gcggtcattc cttcgtgaaa agaaagccgc aattccggaa taatcgcaaa
     3421 gttagtaata ctgatttctt gtagcatcac attcgctcct caacttaaag gtaatgcagg
     3481 aagtctttct tcaataaaac tgcctggtct tcagttcgtg taatcatcaa aacattatcg
     3541 tcatcattga taatcgaaaa taattctttc ttgtaacgtt tatcaatcaa atttgctgct
     3601 gccgaagcat ttcccggcaa tgttttcaaa ataacaaatt tttccatttg gtcaactgcc
     3661 acgaaagcgt cttttaatag tttttccaat ttagtattta catcttcgtt tgtttcagct
     3721 ggtatgctat aacggtagcc gccatctgaa gccggtacct tgatcagttt cagttccttt
     3781 atatctctgg aaatcgtagc ttgagtaaca gatattcctt tgcttttcag gatttcaaca
     3841 aattcttcct gctttcggat atcttgctca ctcaacaatc gagtaatcaa acgatgccga
     3901 tctttttttc tcattacgtc ttcgctcctt agcatattct tcttaatcaa tgatagctta
     3961 tttccttggt ataataaaga agaatccgca tacttctcac ttgattttca cagttacaat
     4021 ttatttatgg tcaaactgtt cgtgtgcatt tgaaaccact tctgccatat taatagctga
     4081 attgattgtt ccgctttcgg gtactttcct caagtgagcc aagaactcga tatttccttc
     4141 tccccccgtg atcggagaat aacttaattc cagcacatca tatccacctt gtgccgcaaa
     4201 tgacaaaatg tcttctaaaa ctttttgatg ggtctgaggg tcacgaacaa ttccgttttt
     4261 ccctacagct tctctgcctg cttcgaattg gggtttgatt aaagcaatca cttctccctc
     4321 ttcttttaaa atagcatgta atggaggcag catcagtttt agtgaaataa aagaaacatc
     4381 gataacagca acttctggaa ttcctaaggt aaagtcttcg ggttttgcat aacgaaaatt
     4441 cactctttcc attacgacga ctctaggatc ttgtcttatt ttccaagcta gctgattgta
     4501 gccaacgtct aaagcataac tcatttttgc gccattttgc aaagctgcat cagtaaatcc
     4561 gccagtggat gcaccaatat ctaacaatgt ttttccttca acagatagat caaatgcttt
     4621 gagtgctttt tctaatttta atccccctcg agaaacataa ggaagttttt tacctttgac
     4681 tcttaattca ctactcactg gaattttttc tcccggttta tcaaaccgct cgtttttttc
     4741 gttgtaaatc aaaccagcca tcactgaacg tttggcttgt tctcttgttt caaataatcc
     4801 ttgtttgacc gctaatacat ctacgcgttc tttttccatt ctttccctca tttctccaca
     4861 tcaaattgct tgatcatctg gcgcatcagc ccgccatcaa aagaaaaaac gtcctcttct
     4921 aatttgtcta tgatcttgtt ggcggataac agctcaatct ccaacgcctc acgtgtcttt
     4981 tctaggccta ataaacgcgg gtaagtattt ttttccatac gttcatcttt accagctgtt
     5041 ttccctaatg ttttcgttgt accaatcaca tcgagtagat catctcttat ctgaaaagct
     5101 aaacctaaat gttcggctaa tcgttgaagt agcaataaga tttcttcagg ttgcttcgct
     5161 aatatgccac cagccagcaa ggcataacga atcaaatgcc ctgtctttct ttcatgaata
     5221 aatgctaatt cttctaaaga aagctttttc gattcgccct cgatatctgc agcttgccca
     5281 gcaaccatac cttgtgatcc cgcacaaaca gctaattgct gaagcagcag aagcttagga
     5341 gaattaccta agtgtgccat actgattagc tggaatgctc ctgtaagcaa accatctccg
     5401 gccaatatag ctaatgcttc gccgaatact ttatgattgg taggttttcc tctacgaaga
     5461 tcatcattgt ccatcgcagg caaatcatcg tggatcaagg aatacgtatg caccatttct
     5521 aaagcagctg ctacttgata gacgggaaca tcaataggct catcaaagga agcaacggcc
     5581 gttaaaagta ataagggacg tattcttttc ccgcctgctt tcactgaata actcatcgca
     5641 tcatagagtc ctctatccgt tgtatgctca tctaaaaaag acaagatttc tttttctaca
     5701 gcaggtagat gaatagctga aaagtcagtt aatctcatct cagctttcct cgtttccgtc
     5761 aaaatcaact tcttcatttg attctgtcat cattttcgtc aaggtctctt ctgctttagc
     5821 taatgtatct tggcaatgtt tgcttaattc cattcctcgt ttaaacgaat ctagagctga
     5881 ttctaatgga acgtctcctt gttctaactg catgacaatt ttttctaatt cttgcagtga
     5941 ctcttcaaaa gttggatttt ccatattttt attctccttt gtctatctct tgtacttgtc
     6001 ctttaacgat tccatcttga taatggatcg tcagcaaatc cccttgatga atctcggtga
     6061 cactttttac tacttgatca tttaacgtcg tatagctgta gcctcttccc atgattttca
     6121 atggactcaa caaatcaaga gattgaacag cttgagcaaa acgctgctgc tgttgtttca
     6181 tatattgttg gattttctct tctaagcgtt tttctagata agcagtttct tggcgagctg
     6241 ctttaactcg ataaagcgga gccacttgtt ccaattggtg gcttaatgcg atcgtttgtt
     6301 tttctttcgc atgataaatt tgctgtgtag cttgatataa tcgctgtttc aactggtcta
     6361 atttgatggt ctgaccttca tacaatcttt caggctgccg aaatacatag gaacgtcgag
     6421 cacgctcgaa ccgttcttgt ttgcgctgga tctggcgtac aaacgcctgc tgcaatctag
     6481 cttgccgttc ttgaatgcgc atcaactctt ctgacaaaac aggaacagct aattctgcag
     6541 ctgctgttgg agtggcagcc cgaacatctg ctactaaatc agcgatcgtg gtatctgttt
     6601 catgtcctac agatgaaatc accggcgtat tagcttgata aatcgcccga gcaacccgct
     6661 cttcattaaa cggccataaa tcctcaatcg aaccaccccc acgaccgatg atcattgtat
     6721 cgaaattgcc catctcttct actctctgga tattcctgac aacattgtcc gctgcttggt
     6781 ttccttgtac aactgttggg aacaaaacca attggacaat tggatatctt cttttcaccg
     6841 tcgtgatgat atcgcggata accgctccgc ttggactggt aaggaccgcg attcgctttg
     6901 ggaaacgtgg cagcattttt ttaggccctt gaaaaaggcc ttccttcatc agcttttctt
     6961 ttcgttcttc caattcttga tataaagcac ctattccatc aggctccatg tgctctacat
     7021 agatttgata agaacctccc gcttcatata atgaaatacg cccaacgaca aggactttca
     7081 ttccttcttt tggctggaat cgtaattttt ggaatgctcc tttgaacata atagcagata
     7141 tttttgcatg gtcatctttt aagctgaaat attgatgggc attggcacgt aaacggaaat
     7201 tcgatatttc gcctgttaaa tatacgcgtt ctaaataagg atcggcatca aattttcttt
     7261 tcaaatactt cgttaatgta gtgacagtta aatattcttg tgccatctat tcacctgctc
     7321 caaaagcttc ggcagatttt acggtttgat acatcagcat cgtgatagtc attggcccta
     7381 caccctttgg cacaggagtg atccagcctg caataggctc cacttcatca aatttcacat
     7441 caccgatcag cttaccgtta gcatcacgat tcatccctac atctatcact acagcacctg
     7501 gttttacgaa ttcttttgtg acaaaatgtc cacgtcctat tgctacgact aaaatatctg
     7561 cttcttgtgc cagttcagcc agattttcgg ttttagaatg agcaacagta acagttgcat
     7621 ctgccatcaa gagtagctga gccatcggtt taccgacgat attgcttcgt ccgataacta
     7681 ctgctcgttt acccgccgga tcgatagaat aagcttcaaa cattttcatg atgccgtatg
     7741 gagtacaagg aatcttgtcc ggtttacccg caaggagtct gcctaaattc atcggatgaa
     7801 aaccgtctac gtctttttca gggcggatag ctaacaggat cttttcttca tctatatgct
     7861 ttggcaatgg taattggacc aatataccat gaaaactagg atcttgattg tatttttcaa
     7921 tttctgcaag tagttcgtct tcagaaatcg tctcaggata acgctctacc aatgaatgga
     7981 ttccgatttc ttttgctaca cgttctttat ttcttacata gatttggctg gctggatttt
     8041 cccctaccaa taaaacgact aatccgggat ggataccatt atctttcaat ttttggattt
     8101 tttcagcaat ctctgcctgc attttttcag ctaattcttt tccgttaatc aattctgcca
     8161 tctaaccact cccagatatt ttttgtgttt tcattctacc atagaatttt cccgatttat
     8221 aacaggttta tgatgattca tagaaaaaag ctaggactta cgccccagct tctaattctt
     8281 tcaatacatt ggataaaaca ccgttgacga atttacgtga acggtcatca ctaaatgttt
     8341 ttgccaactc gattgcttca tttaaagcaa cagccgctgg tacatctgtc acataagtca
     8401 tttcaaaaat cgcgatacgc aagatcacca aatccatttt tgagatccga ttgatgtgcc
     8461 aattgttttt taaatgtttt tcaatcactt tatccaattc atcttttttt gcacagacac
     8521 cgccaactag cgtatcaaga taaacaggaa caaactctga ttcatcttcg ttgatcatgt
     8581 cgcggtggtc taattcgatt gcgttgaaaa tcgcatcttc ttttgttagg tctgcattga
     8641 agtctaatgg aaataaagcc tgcaatgcca tttcccgaat ctcgtgtctt gataattctt
     8701 tattcattct cttcctcttc gtcttcaaaa agttcttcga ttgttggttg ttctaatttt
     8761 tcaggaacaa cagctactac atggatattg acttcagata aatcgatatc cgtcatgaaa
     8821 aggacttgct ggctgacccg ttcctgcatt tccattgcta ctttaggaac tgaaacacca
     8881 tattctagat aacagtaaag atctactttc aagccatctt cctcgtttgc taagtaaaca
     8941 ccttttccgt gagctgcacg tcctaataat tcagtgacat tgctggcaaa agttccgcgc
     9001 attccgtata cgccttctac tttagaagct gcaatcccga taattacttc gatgacttca
     9061 ggagcgatca cgatctctcc taaatcttgg tttgcgttta aaatcaaatt tttttcatct
     9121 gccatttatt tattcctccc tttgcctaag cacgagatac atccgaattc tctatgatgc
     9181 ggcatagtga tcacgtggta agaaaactgc cgccgatcag ctgcaaactg ctatgaattg
     9241 gagaaaacac ccaactttat tatctcttac agcttaaaag ttcttctata gtgtatcatt
     9301 aaatcgagtg attttctata acaaagtctg tgaacactga tttttacgct tacttcttct
     9361 attgatgaaa ctataagatg atcaattctt ttggtgaacg agtcaacaca cgatttccat
     9421 cttctgtgat caacaagtca tcctcaatac gtactccacc gattcctggt aagtagatcc
     9481 ctggttcatc agtgatcaca tttcctggta caaattgctt ttctgcacga gaagaaacgt
     9541 ttggtccttc gtggatctct aaaccgatcc catgtcctgt agaatgtcca aatgcttccc
     9601 cgtaaccatg ttttgaaata taatctctag caactgcatc taattggaca ccagtcattc
     9661 ctggttttgc agcatcaata actgctaatt gagcatctaa gactatttga taaatttctt
     9721 ttaatttttc cccaggatca ccaatagcga atgtacgtgt catatcggaa acgtaccctt
     9781 cgtaatagca accaaagtcc aatgtgatca agtcaccttg ttcgatgatt tttttgcttg
     9841 ctacaccatg cggcatagcc gaacgcaatc cgctagcaac gatcgtatca aaagaaacac
     9901 ctgaagcgcc aagagaacgc atataaaagt ctagttgatt tgcgacttca atctcagtca
     9961 tgcccggttg gatcattttc aggatgtgat catatgccat atccgcaata tgacatgctt
    10021 tttcgataat agcgatttct tcttcatctt tcacttctct gagttcttcg atcatctgtg
    10081 aaacaggtac taattccgca tcgatgattt cttctaaaac cgaatattct aaaaatgaga
    10141 ctgttgtttc ctcaaaagct aatgagtgca gttcttcttt gcgtactaag tttgctacct
    10201 catcaaaaat aggtccgaca tttttaataa tttcaaaccc ttgagcctgc gctgccgcct
    10261 gctcggtata acgaaaatca gtaataaaaa atgctttttc caaagtaata acagctaatc
    10321 ctgtcgtacc tgtaaagttc gttaagtaac gaagattgta cggactggta accaaaaatg
    10381 aatccaaatt ttcttcttgc atttttttgc gcaatttttc tacacgtagc atcataatga
    10441 aactccctct ttctttgcac gcttttttcc attatagcaa acttttcttc gtacacgaca
    10501 gttaaataaa aatttccgga aaacttcttt ttattttaaa taaataaagc caaaaaggag
    10561 tcacagtctc gctgcaactc cttttagttt actattttgt aaaaacttat gatcgttttc
    10621 caaagaaaaa tgagacaact gctaccaaaa tcactgcgcc taaaatagat ggaataagtg
    10681 ccatacctgc agcttttggt ccccattcgc cgaaaatcgc ttgtccaata cttgaaccga
    10741 ctagtccagc aatgatattc gttacacagc ccatcgaatt tcctttactg gtgatcgcac
    10801 ctgcaattgc tccgatcacg gctccaacaa tcaatgtcca taaccaactc ataatataac
    10861 ctccttcttt gctaatcaat tttagcatat gggatttaaa ggggacaaat aattggtttt
    10921 gctatttcat attttcttct gcaaagtaaa aaaataaaga aaacctcctc ttagaagttt
    10981 tctttatttt ttacttgcgt ttaaacatac tacgaatacc acgtttcact acatcaaaga
    11041 aactcaatga ttgtaccatt ctatcttcat ctacatattc tctgatcgca cgaagcactt
    11101 ttttaggttc tttggaagaa aatgtgtatg taccattttt tttcgtttga atggcatatc
    11161 gaggaatcca ttttcccttt agcatgactg atgctagtac ataatccact tcttcccatg
    11221 gaatttggat atatttgcgt ctatctcgcg catggtaaaa ctcaaaacca ttatcaccta
    11281 tcatgatttg cccgtaatct gtcagacccg taaacgaagt agcatcaatt accaagtcta
    11341 cttttgtatt gattgattga accattttct ccctccagat atttgtttat gaacagtata
    11401 ctatataaaa aaagctcggg acaacgcccg agctatattt ttatggatta taaaagtccg
    11461 atgacgtgtc caacaacacc gactacgaat aaaccaagga tgataacgat tggagaaacc
    11521 tttttcttaa gcaaccacat acataacaat gttaatccta atgcagctaa accaggaatc
    11581 aattggtcta agttgtcttg taatgttgtt accttttcag gagaaagggc taagccatta
    11641 ttaacttgtt caaatgcact cttgattcct tcaccacctg aaggcaattt atcccattcg
    11701 atgtaagcac ctttatctaa ttttacagtt gatacaactg gtaagaattt gattgatacc
    11761 catctttgta caagggcagc taatacgaac atccctaaaa ttgaagcacc ttttgttacg
    11821 tcttgtaaca atccgccaga aaggtcatca gtaattttag aaccagcttt gtagccaaat
    11881 tcttgtgtat accacatgaa tgcccaacga ataatgttcc aacctaagaa gaagatgatt
    11941 ggtccaagga tatttcctcc catagctaat gaagcaccta gtgcacctag cattggacgt
    12001 actgtaaacc agaacactgg gtcaccaaca ccagctaaag gacccatcat acctacttta
    12061 accccttgaa tcgctacatc atcaacaggc gcgccattcg cacgttcttc ttccagagcc
    12121 aatgtaaccc ctaaaattgg agaagcaatg tatgggtgtg tattaaagaa ttccaagtga
    12181 cgttttaatg ctgcagaacg ttcttctttt gttttgtata attttttgat tgctggaatc
    12241 atagaaaatg cccagccacc gttttgcata cgttcgtagt tccatgaacc ttgaatgaag
    12301 gtagagcgcc acgcaacagc taaacgatct ttttttgata atttgatttt ttcttctgcc
    12361 attttatttt cctccttcaa gattaatagt cattcaaaat gtcgcctaaa gggtcaccag
    12421 agttgcttcc gcctccatta tttgatgaac cacccatttt agaaaggttc aagtaaataa
    12481 gagctaatgc aacacctaaa gcacctagag caatcaatgt taattgagaa attgcagcta
    12541 caacgaaacc aataacgaag aatggccata cttcttttgt agccatcatg ttgattacca
    12601 aagcgtaacc tacagctacg accattcccc caccgatagc cataccatct gttaaccatg
    12661 ctggcattga ttcaaggaat gattgcacag tttgtgctgg gataaatagc aacgctgctg
    12721 ctgggaccgc gatacgaacc ccttgtaaac atacagcaat gatgtgccac atttcaacct
    12781 tacggatgtt tccttcttca gcagccgcat ccatcaaatg aacgattgga acagcgattg
    12841 tacgtacgat cattgttaag aacaaccctg caacagccaa aggaacggca atcgcgatcg
    12901 cagaaggaac acctttaaca ccttgtccac ctaaaactaa aataattgct gatgctactg
    12961 atgctaatgc agcatctggt gctacagcgg caccgatatt tgcccaacct aaagcgatca
    13021 tctgaagcgt accgccaagt acgataccag cttcgaggtt accggtaact aaaccgatca
    13081 atgtacatgc cactagtggt tgatgaaatt gaaattcatc aagaatacct tccataccag
    13141 ctagaaaggc aactaatacg actaaaatta ttgaaataat agacatgata agcctcctat
    13201 aaattttaat attatttatt acgcttttgc taattcagct tttgcttttt tcaaaatatc
    13261 atccatgtta tcgcgtgaat cattaggtac tttacgtaca tcgaatttca cacctttttg
    13321 ttcaagcttc tcaaacgctt caacgtcttc ttgtcccata gacaatactt tacttacaac
    13381 gactttaccg accgaatgcg ccattgaccc aacatttaat tctttgatgt ctacgccacc
    13441 ttcaacagct gtcaatacgt cttcaggatt ttcaaataaa agcaatgctt tggtatttcc
    13501 aaaacgaggg tcttttgcta cttcgatcat tttgctaata ggaataacat ttgcttttac
    13561 acctggagga gcagcttgtt cgattagtct cttacgcaga tcatcctttg atactgcatc
    13621 tgaaacaacg ataatacggt ttggttgcac tgcttttgtc caagctgtcg caacttgtcc
    13681 atgtaacaga cgtgagtcaa cacgtgctaa tacatatttg atttttccgt ctccgaccac
    13741 agttccttct ggaagtgctc ctttaggttg tgcgtcttca actgctgctt tcggtgcttc
    13801 tgccggttct aattcttccg gttttacttt tacaccgtct tttgctgttt caatgatgtg
    13861 tgctgcaatt tcatgagcag attccattga aaagcgtgat gcgtaggctt caatcaacat
    13921 tggtaaattc aaaccgctga cgattgccca tttatctttg tgctcttcga ataatgtgtt
    13981 tgattgattg aacggtgttc cgccccataa atcaactaag aataacactt cgtcttgatt
    14041 atcaaaagaa gcaaccgctt cttccaattt ggctctcaag tcatctggac cttcacttgg
    14101 tttcaaaatc acggctttga cgttttcttg ttcgccaaag atcattgaac cggattgtaa
    14161 gattccttca gcaaattgtc catgacttgc taggataatc cctaccatat ttatacctcc
    14221 tatttacttt tgttgtaaca aattcaaaaa tattaataat tgctaaccat tacaacagaa
    14281 ttatttgacc ttttccaaca accattcttg ctacaccttt ttgattttcg ctagtagttc
    14341 catcaaaagg attttcctgt cagcaggtac ttttcgaatc tctaactcca cttcttgact
    14401 gttcaagtaa cgaaaggaat caatatcttg ttgatttact gaaacaaaat tggtaatcat
    14461 tgatttgcct tcagtaaaac tcataccgcc gatattcaac gacttcaact gtacaccgca
    14521 gcggacaacc gcttcaacat cttggggatt ggtgaataaa agcatcactt ttgctcgtga
    14581 taataatcca ctatgataga tttgaatcat tttctgcacg gttattacat ttgctgtgat
    14641 ccccggcggt gcagcttctt ttagtagaaa ctttctcaat ttatcttgag cgactacatc
    14701 gctgatcaca atgatacgtt caacacctgt ttgcttcgac caaactgttg cgacttgccc
    14761 gtggattaaa cgatcatcta tacgtgccaa tcgaatatcc atctgcaaaa ctccttcttc
    14821 ctcactactt cacagaaacc cctatcattt ctgtgtgaac aaccacctcc tagcacacac
    14881 tactataagc aaaaagcgtg ccaacttttt tacgatacac taattgaatt taaaggattc
    14941 ttaaccaata cacaaaaacg atacactata aaagtgtatc gtttttgtgt attcatggca
    15001 cagtgtattc ttttttatct aactgattat ggactagacg tagcagataa tacatttctt
    15061 ctatcggcac ttttactttt atctgatctt ccaacagaac aactgaggct gccaattggc
    15121 tataaagagg atcattcgtt gtatttgtca attcgttttc ttccacagtc aatggttcat
    15181 tccgaataat acgttcgatc attcctgctg tgtgcatcac taggttgatt ttgaatccat
    15241 attcttcatc gccgattccc gtcgtctgag agatttgtgt agaaaattgc cacattggat
    15301 cgattaactt actaccatta ataaagatga agttatcaga gataaactca acacacgtat
    15361 ttttagctga ctcttcatct agggagatga attcagtttc ctccaattct gattccatca
    15421 gcaactgatc caaaatgact tcgatatttt gatcaataaa acgttctaaa ggaataaatg
    15481 gggcttggat attcaaatca gtaatcccag tagtagctat gatctgatat tctttttgga
    15541 taactggcag ttcttctttc acttccacaa tcgacaaagc tagaacttct aattctgttt
    15601 cttgacgctt gtttaccgct cgttcgatca attctttgat tctttgtgct gtaccttcgc
    15661 cagatgcgca gatagccaaa acagcttttt tcttatgaat aggttttgct tcctgaacag
    15721 attctacaga agatatttct gcgtaacctc gaaaattttt caatgattca tgcaacatat
    15781 ctagatctgt ccctaatact gagacctttc gtacagtttc caaaactaga gaagttgtta
    15841 ccatatcaac agtacgtact ggaattccag tgtctctttg aatttgcgaa ttaaacgacg
    15901 caagggaccc catatctact aagagtatga ccccgcttcc ttcatctact tcttgtacat
    15961 tgcgttcaat tcggtccaat gctgttttcg gatccatatc caaaggcatg tctactgctc
    16021 gtacgttctc tgcatctaac aactgttgga caacttggac catactgctt gctgtgctgt
    16081 ttccgtgagc tgcaacgact acaccgattc tgccgcttgc ttgatttgcc cgtaacgaga
    16141 cgagtagaac ggtcaagtaa tagtcttcac tttctggaat ctccacttga aaatacgttt
    16201 cgatataact acgcacttct ttcgcaacag catattcatc tggaaaatca aaagccatct
    16261 cacggatgtt atcattcgta tgccgttctt ctcctaagtt gatttttttc aaaaaagaac
    16321 tgatatgcaa gctcatagca taaataaagt tttgctgaaa ctcatatggt aaagatcttt
    16381 tgaccattac ataaatctga ttggtcactt ctatgatttt cggatctaca aattctgcta
    16441 atttgctgtc tgcattaaaa gaaaaaccat ggtctttata gaaagacttc agatggatgt
    16501 tgatatctgt agaaatgaaa tgattgattg cttcttgatc caaaccatcc gacttcagta
    16561 aagctgcttt atctccgatg atatcatata gattataagg taactcatag gagtccgatt
    16621 ggattttcat gatcgtatca tttggtgcta cagttatctt tggctccaat attttagaaa
    16681 gctctgccat tgcactgcgg ttgcttgcta attgaatcaa tccgctacga atcccttctg
    16741 tcaaatcatc gattgtgatc gagatttcgg gtgattgcat atgatttaga aatcctcgtg
    16801 cacatactaa ctggatattt gacttcaatt gtcctatatt tccataggtc acactgccga
    16861 tcaatgcttt tgctacatct tctgtcaaag aaatctttcg ctgcgtgcgg tttgcttcgt
    16921 gggcaatcat gatttttact aaatcgactt tctcatttgc aggacgtttt tcaaaagccg
    16981 gaagtttgat attgattggg atacgccgaa caaaagtttc taatagagaa gaacctgggt
    17041 cttctgtggt cgcacctacg atccgtacat ttgcttcatg ggatttcgtt gtttccccaa
    17101 gacgactgta agttccatga tccataaagt aaaagatcat ttcttgacct tcaggcggca
    17161 accggtgaat ctcatccaaa aacagcatac cgccatccgc ttgatcgata atccccattt
    17221 tttcttcatc tgcgcctgta aaagcacctt ttgcgtaccc aaataaatga ctcatcaaaa
    17281 gctcagggtt attggcataa tcagcacaat tgaaaacaat cagttccgtt tcctcatcta
    17341 ttacatgatg cgcttttgca aaatgataca tcgcgtgtgc aaaataagtc tttcctgatc
    17401 cggtaggtcc tgtaatcaaa caatttaatc ctcttggcgg atacaaaatc gcagcttttg
    17461 cctgttccac tgaatttttc atgctgccgt tagctccaat gatttttgca aagatatcct
    17521 tagtatctat ttggagtgta tttttttctt cagagaccgg cgtttctttg taactgacta
    17581 catgttttgt aactggcttt acgtgcgtaa cgagtgtttg atatatgtaa cgtactggtc
    17641 gtccgtctgt ctttatcagt tttccttcgc gcactagctg attcagatct ttactgctat
    17701 ttgttcgctg aatccctaac acttcagcaa tttcctgtgt tgttactcct tgatcatatt
    17761 ctgcctttgt taaatgagcg gttttttctt tgacatacat ataaattcgg tcaatgcgtt
    17821 ttgccaatgg tatcgctcct tttctataga ctattgtact taggcttcaa aacataatac
    17881 tatgtattta tttctgtttc gtcaactatt tacctgattt tgttttgttg ataacacgcg
    17941 gatagataga aatgttcaat ttaaaagaac gaaaaatccc gatacgattt ttataatgga
    18001 aacaagaaaa agaacactgt ttaccatata attatttcac tgatagcaaa caatatagct
    18061 tccatcaatt gaaaacgata gttatcaaaa catcctgatt ccaaattggc aaaaaaatat
    18121 taagtgtaaa aagacaaagt aaacttcgta gcctccacta caacttttat ttt
//
LOCUS       DACBZK010000055        17107 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.057, whole genome shotgun sequence.
ACCESSION   DACBZK010000055 DACBZK010000000
VERSION     DACBZK010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.057"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            7..1398
                     /locus_tag="IVD66_001971"
     CDS             7..1398
                     /locus_tag="IVD66_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAP6146175.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIETSGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            1414..2454
                     /locus_tag="IVD66_001972"
     CDS             1414..2454
                     /locus_tag="IVD66_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP6146176.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            2473..3558
                     /locus_tag="IVD66_001973"
     CDS             2473..3558
                     /locus_tag="IVD66_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAP6146177.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            3591..4553
                     /locus_tag="IVD66_001974"
     CDS             3591..4553
                     /locus_tag="IVD66_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HAP6146178.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            4546..5979
                     /locus_tag="IVD66_001975"
     CDS             4546..5979
                     /locus_tag="IVD66_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HAP6146179.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKGELI"
     gene            5976..7046
                     /locus_tag="IVD66_001976"
     CDS             5976..7046
                     /locus_tag="IVD66_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146180.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            7033..8454
                     /locus_tag="IVD66_001977"
     CDS             7033..8454
                     /locus_tag="IVD66_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAP6146181.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            8467..9474
                     /locus_tag="IVD66_001978"
     CDS             8467..9474
                     /locus_tag="IVD66_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP6146182.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            9486..10490
                     /gene="neuB"
                     /locus_tag="IVD66_001979"
     CDS             9486..10490
                     /gene="neuB"
                     /locus_tag="IVD66_001979"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HAP6146183.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            10487..11635
                     /gene="neuC"
                     /locus_tag="IVD66_001980"
     CDS             10487..11635
                     /gene="neuC"
                     /locus_tag="IVD66_001980"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HAP6146184.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            11608..12285
                     /locus_tag="IVD66_001981"
     CDS             11608..12285
                     /locus_tag="IVD66_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAP6146185.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            12275..13417
                     /locus_tag="IVD66_001982"
     CDS             12275..13417
                     /locus_tag="IVD66_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAP6146186.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            13430..14407
                     /locus_tag="IVD66_001983"
     CDS             13430..14407
                     /locus_tag="IVD66_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP6146187.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            14407..15315
                     /locus_tag="IVD66_001984"
     CDS             14407..15315
                     /locus_tag="IVD66_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAP6146188.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            15316..16068
                     /locus_tag="IVD66_001985"
     CDS             15316..16068
                     /locus_tag="IVD66_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HAP6146189.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            16073..17020
                     /locus_tag="IVD66_001986"
     CDS             16073..17020
                     /locus_tag="IVD66_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAP6146190.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         6164 a         2190 c         3090 g         5663 t
ORIGIN      
        1 gtatatatga ataaaaatgg agaatggagt gctgcacgac ggatattcat tatattaatg
       61 gatgttattg tatacaatgc agcaatatat agtagtttct tactgaagtt tcgtggagag
      121 atcccattac gaaatttaga aactttccaa cactcagcaa ttattatttc agtgattttt
      181 attgcgttga acattttgtt gggtgcatat gttttttata atcgaatgat cagtgacatc
      241 gtgtttgtca cagtcatcgg tcaggtattg atgacactag ggatcatggt agtgactttt
      301 gcgggccgct ggtttgcttt tccacgtctt gttatcttac tttcatttgt tctcggtacg
      361 cttttcttaa gtatctatcg tattctcgta tataaacttt atttacgcgt aagtcgagat
      421 aaaaaggtcg tcattattgg gttagaaaag gatgtcgcac cagcaatcca aaattttggt
      481 tcaaagaaaa acaacaaaca taaagtcgaa gcagtcattc ttgataacta ttatgcaaac
      541 atcaaaaata tgattaaaga catcgatatt gtctatcttg cttctcatat cgaagaaact
      601 gaaaaaatca aaatctatca attagttact aaaaatgaaa aaaaattgtt tttgaataca
      661 acatttgaaa acttgacatt gatcaatcca aatattatga atttcgaaga tgaaagtatt
      721 attgaaacat ctggatttag aatccaacct gaatatgaac tattcaaacg tttgtttgat
      781 atcatcgttt cacttgtttt attagttatt gcttcaccat ttatgttatt cacagcaatt
      841 ttagtcaaag tgacatcacc gggaccaatc atctataaac aagtgcggat cacaaaaaat
      901 caaaaggaat tttcaatcta taaattccgc tcgatgaccg ccacagccga agcaaaatct
      961 ggaccagttt tagctaagag caatgatgca cgagtaacgc ctgtaggtaa atttattcga
     1021 gctgtccgct ttgatgaatt accacaaatc ttcaatgtgc tgaaaggcga tatgtcgatc
     1081 gtaggaccac gtcctgaacg tcctttcttc gtcgatcagt tcaatgcaga aaacccttat
     1141 tactacttac ggcataatgt tcgtgctggt atcactgggt atgcacaagt ctatggaaaa
     1201 tatgtctctg attacaacag taaattacgt tttgatttac tttatatcaa aaaatattca
     1261 ttgatgcttg atttaaagat cttgctgcaa accatcaaga tcctatttga taaaatgtcc
     1321 tctcaaggac ttgaagaaga cgaaaatgtg atctcattgg cagaaattgc ttttccgaat
     1381 gaaaaaatct ttcgctagtt gggaggcgta aaaatgaaca atccgaaatt cagcataatc
     1441 gtaccagtat acaatgcaga agcaactatt ggtcgaacga ttgatattct aaaagaattg
     1501 gattatgaag agtacgaagt cgttttagta aatgatggat caacagatca aacacaggaa
     1561 atcattcaag aactgattga aaatgatgaa cgttttgaat tgattactac gaccaatcaa
     1621 gggcccggat tagcaagaaa cgaaggaata agacagtcaa aaggagaata tctcttattc
     1681 ttcgatgcag atgacacgcc agtaaaaacg atcttgtcag attatgatca tttgctagaa
     1741 aagagtccaa aagcggatct tgttgttagt tcgtttgttt ttcgtacaat ggacgaggga
     1801 agaatcgttt ccgaaaaaga aaacttagtt acagaatgtc actatctaac tcacgaagag
     1861 tttataaaag acatgtatca gttaatgaat gaacagttga tgtatgttgt atggaacaaa
     1921 tgctatcgta gcgatattct gaaaaataac caaattctat ttaaaactta taatagttgt
     1981 gaggatcgaa tatttaactt acattattat gaatactgtc atcaagtgat catgaaccca
     2041 aaagtagaat atatttatga atttgaaggt gggaagggga tcactaatca ataccgacct
     2101 aacaagttcg aaacatttaa agaattctat tcattagcaa atactgtaac agacgatatt
     2161 aataaagacg gtatggcggc gcttctttta aaagggacaa cttcagttat tttttctatt
     2221 tatagtacct ctgcaagaac ttcaaaagag aagaaagacg aagcaaagca gatattgagt
     2281 gatccagtga tccgagaagc caagcaaatt gctaagacgg attcttcagc aaaaaaaata
     2341 acaaagttgc tttacaatat gccagctcca ctatttttat ctgctgtaaa agttggaagc
     2401 ttcgttgaag tgaaaatgcc agggttaatg gctgctttga agcgagtata ttagttaatg
     2461 gaggaaaata taatgaaaag aattttgcat tttcagggac gaatgggttt aggtggagca
     2521 gagtctttca tgatgaattt atatcgtaaa attgatcgta caaactatca atttgatttt
     2581 ttgatttatg aagattatgc agatgttcaa gactatcatt cagagattga aagattagga
     2641 ggccgtattt ttgttgtacc taatcctaag aaaaatattt ttaaatattt aatagaagtg
     2701 aataagttac taaaaaaaga atctttttct atagttcaca atcaggttta ttttggcggg
     2761 ggaattaatt tatggttagc caaaaagaat ggaatcagac agagaattgc tcatagccat
     2821 gcaactgaag atggaaaatc tcaaaatatt gtaatgaatg tattgcgtaa atttttaacc
     2881 aaattgttgt tacaaaatgc aacagactac cttgccgtta gtcaagaagc tggtgaaagt
     2941 ctgtttcaaa accatccctt tgagatagtt cataatggta ttgatttaga gctttatagt
     3001 aaaaattcag aagctaaggt taataagaga aaagaattgg atatctcaat gagtactttt
     3061 gttgtgggaa acattggacg attagagaaa caaaaaaatc aatcttattt gttagagatt
     3121 tttttagaaa tactaaaaat gaattctgat tcttacttga ttttagtagg tgaagggtca
     3181 cttagaaata aactgaaagc caaagcagta gaattggata tagagaaaag agtaaaattt
     3241 ttaggagaaa gaaacgatat tcccgagtta ttatctgtga tggatgtttt tgtaatgcct
     3301 tctctttatg aaggtctgcc aatggttgga ttagaagcac aagcagcaaa attaaaatta
     3361 gtcttagcag atactatttc caaagataca aagttaacaa ataatgtgga ttttgtatca
     3421 ttagatgaaa caccacaaga atgggcaaaa aaagtaataa aagagccgta tgctaataaa
     3481 ataacacaag aactaaagag ttatgatgtt tcgtacacta ctgaacaaat ggagagtata
     3541 tatagtagag atcattaaaa atgttcaaga tattttagga gtgattattt ttgaaaatat
     3601 gttatttgat attggcatac aatgatattg gcaacttaaa gagattggtc aatcgattga
     3661 acgaaaatgc agtttttatt attcatatag ataaaaaaac tgatatagaa ccatttattg
     3721 aagcatttaa atcatatgat aatgttgaat ttttatgtaa taaaaaccgt gttaaaattt
     3781 attggggtgg tttttccatt gtacaagcag aaatcaattt agtaaagaga gcattacaaa
     3841 atgagaaata tttaaaatat gtattattat ctggtgctga ttatccaatc aaagataatg
     3901 agtatattta taattatttt aaaaagaata gttcagtgga gtttattcgt ggaatagatc
     3961 tagatcaaat taaacataaa gaattttatt ataaacatat agatgtatat caaaaacatg
     4021 attatcctag aattaatagg aataacacaa ctgcatttaa aatttttaga gctataatta
     4081 atcgttgtct gaggatgatt aaacttcccc caaaaattag acaccataaa tttgatttgt
     4141 atcatggttc tcaatggtgg gctttgtcga aagaatgcct aacagaatta atacaaatgt
     4201 atgaacaaaa tcaacaagac tacctgaatt ttaaaatagg tatgtttgcc ccagatgaaa
     4261 aattttttca tacacttttt tttaattcct cgttcaaaaa taaaaatgtt attggaggac
     4321 cagatttacc acttgaattg aaaaatattg aagaaactac tttacaaact tcgaaattag
     4381 caaatattca tattattgat ccttccatga acaaatggtt tgatgaaagg gatatagatc
     4441 aaataaaaga aagtgaaaaa ttatttgtaa gaaaagttaa atcggattac tctgataaac
     4501 tattaaatag aattgataaa gaaattttga aagttggaaa tatagatgaa tagaatagta
     4561 cctgttttag agaagagttt attaagtcga gatgcgtttc gagtaataaa tttaatcatt
     4621 tgtctgcttt attttatgcc tagtactttt aatgtaacta atatcccgat gaaaatagct
     4681 tttgcttggg gtggaattat agttttgtat gaggttttta taaagaaaaa tttttttaaa
     4741 atgcgttttt cttggctact gattggagca atgattagtt ttatcttaac tataatcatt
     4801 aacagagaaa attttttaat tccatctatt tataattttg gatatttgct gattactttg
     4861 atagtaattt ttcctgcaga cttttcacaa agtgaagagg aaaaaaagaa aaaaatggtg
     4921 tattttaata atgttttcat tatcataatt tttttagctg cgctaatatc tatctatcaa
     4981 tttatttttt tgatttctta tcatgtccca acaggaacgc caggattact tgcaagacaa
     5041 ggttttattg aacatcggtt atttggtgtc tatacaagtc caaatgttgg agctatgttt
     5101 ggatatactt ctattatttt aagtttaatt agtgtattaa tttcaaaaat aacaaaaacg
     5161 attcgtgttt tttatatgat gaattttatc gtacaaatat tttatattac actttcttcg
     5221 tctagaggtg cccaggtagt aatttgttct tttttagtat tatttctttt gttgtttgcc
     5281 aattcaaaat ttagaaagag cattagagaa gtactacctg taaaaatcaa atggatggta
     5341 agcatattat tagttctatt ggtatatttt tcttttggta ctaattatgc taaggatttt
     5401 ttagcaacaa ttcctgtatc gattgataga aaagtagaag ttatagagtc aaatgaatca
     5461 gataaaactc cacttccaga aaaagaagta atattacagc attctagtga taactccgaa
     5521 atttcagctg gtcgttttac gatttggaaa gctgcgctta aagttataag accaactttg
     5581 ttatttggtt atggagagac cgatttctat gggaatagcg atgcaaaatt tttgaaaaaa
     5641 gtagatcttg atactacaga tgtgaatgaa ctaaaaagag cacatggaaa catgcataat
     5701 ggatttcttc aagtacttgt atcaagtggt ataattgctt ttatatgtat ctatgctttc
     5761 tatgtgttaa atatctttag tttactcaaa acatttttta gaagtaaagt gaattatgcg
     5821 tttcttggta ttgttttaat ttttatacta tctattttta tagatgaaat ggtggaggct
     5881 catgtacttt tcaataagcg cgatgtcatt tcaattgttt tctggtatta tttgggaagc
     5941 atttcttact tgtatttaaa aaaaggagaa ttaatatgaa gacagctttc attgcttgga
     6001 ctcctttaca tttgattaat atattaaatg tttatcaaaa tttttaccga gaatcaaaag
     6061 gagatttatt tatttattct gaatttgaaa acgctagaag atatagtgag cgtataaaag
     6121 aattagggct atttaatgat gttgtttttg tgaatcaccg gaaaatcggt tcttccttta
     6181 aacgtaaaat taacttgtta actaaccata atcaattttt ctcggatgat ttatccgttt
     6241 atgatgaaat ttttatacag ggggaaaatt atttcacaaa aatacttttc tccaatgttt
     6301 acaaaaaaaa tccagatgta aaactaaatt atatagaaga tggtttgggt acttatttga
     6361 agaagagtat attttcaaca agtaaaaacg ttcaaagagt ttttaaaata ttaaataaaa
     6421 atagcatctt caaaaaaaaa attgacgatt attttgtcta ttgtccggaa ttgttacttt
     6481 atgatgtaaa aaatataaaa aaaattccca aaatagatga aaacagtaaa ttgatgaaaa
     6541 acatacaatc aatctttggg atagaagaag tttttgtcgg agataaatgt atcttttttg
     6601 atcaaccttt attatctgat ggttatggca tagatgaaac agatattttc gctaaagtaa
     6661 atagtatatt ttctggaaaa aaagaaactt taattaagct tcatcctaga gcaaggacaa
     6721 atcgttatgg tgaaaaaaac atattgaatt ccagtttacc gtttgaagtc ttgctacttg
     6781 aaaatgactt ctcttcaaca cttttgatta gtcctatatc tacaatttct ttttcaccat
     6841 ctatgatgtt tgaaaagacg atcaactcta ttatgttggc taaattaatt ttaaatgaat
     6901 atacagcatt atctgaagat aaaaaagaaa cattgacaaa tattgttctt ttctgtgaac
     6961 attataaccg tctatcagaa gaaaaaattt tactcccaga aaactgggca gaattaagaa
     7021 agttggtaga gtatgggatt atttaacaca ctttccaagt caaaattagt taagtccagt
     7081 ttctggtata ctatagggaa tttttttatt aagggaattt cattcataac tattcctatt
     7141 tttgtaaata ttactactca agcagaatat ggtttgatta ataatttcac ttcatttgta
     7201 tcaatttttt cgattcttgt tgggctaagc ctaaattcgg caattaataa tgcaagtttt
     7261 gactataaag atgacataaa tgaatttatg tcatcggtac tttctctagc tacactttcg
     7321 ttaattgtgt tcttattaat agggaacata tattttttgt tttcaaatgc tttttttgat
     7381 atgaaccaac ttgtatttaa tttgatgtta ttacaaagtt ttgctagttt tgtaattagt
     7441 tatatccagt cttattttac gattaacttt aaccatttta aatatttgat tttatctttt
     7501 atatctactt ttttgaatat tgcaatctct gtagctttga tgcagacatt atattttgat
     7561 gataaatatg ttggcagagt agtcggcgga acactgtcat ttgtgttgat aggtttagta
     7621 atttatttaa gaataatgat aaagggtgct catttttttg ataaaaaaca gtggagatac
     7681 gctttaaaaa tctctttgcc gctaatccca cattccttag caaatatagt tttagcacaa
     7741 ttcgatagaa ttatgattaa ttcttattta ggtcctgctg cggggggaat atattcctac
     7801 attagtaaca taggtattat tctaagcgta atatggatgt ctactaataa cgcctgggtt
     7861 ccatggttct atggtgagat gagtaaaaat aatgaaaaaa aagtgaagaa agttagtaac
     7921 tattatttag tagtctttac tttgattacg atgattgtaa tggtagtttc gattgattta
     7981 gcaaaattta tggctccgaa agactattat tctgggttat ctttagtggt tccgataacc
     8041 ttaggctatt tctttcagtt tttatatagt ttaccagtta atgctgaatt ttatgagaaa
     8101 aaaacatcgt ttattgcgat tggtacagta gcaagtgcta tagttaatat actattaaac
     8161 atgattttca tacctaggtt aggaataatt gctgctggat acacaaccgt atttacgtat
     8221 tttttacttt ttatttttca ttataatatc gctaaaaaaa ttacgaataa acaattattt
     8281 gacacaaaaa aaatatgtat cataataatt tttgtatcaa ttttttcttt gatacttcat
     8341 attttaatca atcaaatgtt gattcgttac gttttgacat cattattgat aattagttta
     8401 gttatatatt ttttaaagat taagaatcga attatagatg actataattc ataggaggag
     8461 atataagtgt ttaaaggaaa aacaatatta gtaactggcg gaactggttc cattggaagt
     8521 gaaattgttc gtcagctttt aaaatatgaa ccaaaagcta tcagaattta tagtagaggt
     8581 gaagaaaaac aattttatat gcaacaagag ctctcaaatc acactaattt gagattttta
     8641 attggtgata tcagagactc tcaaaggatt gattatgcat gtcgtgatgt ggatattatt
     8701 tttcatgctg ccgcaatgaa acacgttcca gcaagtgaat ataatcctat ggaagctgta
     8761 aaaacaaatg tgatgggaac tcaaaatgta atagatgcag cgatcaaaaa taatgtaaaa
     8821 cattttgtag gtatcagtac agataaagta gtgagtccta ctaacaccat gggtgcgaca
     8881 aagttattga gtgaaaaatt aataatagct gccaatcagt ataaaggaaa aacagaaaca
     8941 atattttctt gtgtaaggtt tggaaatgtc atggggtcaa gtggatctgt tattcctctt
     9001 tttagtaaac aaataaaaaa caataaagat attactttga cagatgttga tatgacacga
     9061 tttatgatgt caataccgga tgctgcaaga ttagttctgt ctgctgctat gaattcaaaa
     9121 tttggagaaa catatgtctt aaaaatgccg gcaatcaata ttttaacttt agctcaatca
     9181 ttaataaaaa tatataatga tacacatgat gaaaaatata gaggtgaaat aaaagttgta
     9241 ggtatcaggc caggagaaaa attatatgaa gagctaatga ctacagacga aattgaacgc
     9301 tcatatgaaa atgataaaat gtatatcatt ccaccacact atcatgctac tgacgaactg
     9361 tacaaagatt atgaaaaaat taaaatcact gcatactctt cagatgcaac agaattaatg
     9421 agtggacagg aatttattag aatcgcaaaa gagaataatg tcgtgacttg gtaaggagtt
     9481 ttatgatgaa atcagaagta tatgtaattg cagaaattgg tgtaaaccat aatggaagtc
     9541 tagatttagc tttagaaagt attgataaag ctaaagaatg tggagctaac gcggttaaat
     9601 ttcaaacatt taaaacgaat aagctagttt ccaaaaaggc tccaatggca aaatatcaga
     9661 aggataatct taaagaggac agttctcaat ttgaaatgct aaaaaaatta gaattatctc
     9721 aatctgattt tattagaata aaagattatt gtatacaaaa taaaattgat tttttgtcta
     9781 ctccttttga tgaagaaagt gcagactttc taaaacaaat tggtgtacaa ggatttaaaa
     9841 ttggctcagg agatttaaca aatttacctt ttcttagaaa aatagatatg tatgggttgc
     9901 cagttttatt atctacaggt atggctgata ttcatgaggt cagtgaggct gtagattgtt
     9961 tcatagatag tccagttact attttacatt gtacttcaaa ttatccggct agttctgaag
    10021 atattaattt attggcgatt aacacattaa aagaaatgtt cgggataccc gttgggtact
    10081 ccgatcattc attgggatat gatgttggta tttgtgctgt tgcgatgggt gctaaggtaa
    10141 ttgagaaaca ttttaccttg gataaggaac tacctggtcc agatcataaa gcttctttag
    10201 atcctcagga atttgcagat tttgtaaagc atattagaaa cactgaaata tttttaggtg
    10261 atggtgttaa gcgagcaatg ccttctgaac ttagtacaaa agaagtatca agaaaaagcc
    10321 tagtggtcac tgagaattta aatgtgggag atattcttac agagaaatct cttacaataa
    10381 aacgtcctgg aaatggaata gctcctaagt ttttatatca atatattggc aaaaaagtta
    10441 aaagaccaat aagtgcagat agtgttctgc ttgaggaaga tgttgaatga aaaaaatact
    10501 tatagtaagt ggaacacgag ctgattatgg aatatataaa cctgttgctg agaatttact
    10561 acaagataat tgggatgtat catttgttgt ttctggaatg catttatccc ataaatatgg
    10621 atttactaaa gaattgatct tagctgacgg atttagaatt agtggagaag ttcaaagttt
    10681 gtttttagag aacaataagg gaaacatggc tcggtctgtg gcattagaga taaatggttt
    10741 cacaaatata tttgaacaaa ctagccctga ttttgtatta ttactagggg atagaggaga
    10801 aatgttggca gctgcgatag cttgtttgta tcttggaatc aaaacagcac atattcacgg
    10861 aggcgaagtg tctggtactg tagatgaatc aataagacat gccataacga aaatagcatc
    10921 tgttcatttt gctgctacgg aaaaaagcaa agagcgttta ataaaaatgg gggaagattc
    10981 ttggagagtt tttcccgtcg gagctcctag aatagatact attttaaata atagattacc
    11041 tagttttaga gatataaaag aaaaatatca tctaaaattt gaaaagaaaa aatacgtttt
    11101 gcaagtattt catccagttg taaccgaact agaaaatata gaaaaacaaa ttttagcttt
    11161 gatcaattca atggaacaac aatctcaacc aattatttgc attttaccta atagtgatgc
    11221 tggtagcgaa attatcagaa aaatgtacca gaaatattta aaaacggata ttatttatat
    11281 tacgaattta gagccggagg aatacctgac tatattaaaa gagtgcaaat ttatgatcgg
    11341 aaattcttct tctgggataa ttgaagctgc atcattcaaa ataccagtaa taaatttagg
    11401 aaccagacaa aatggacgag aacaatctaa aaatattata aatgcaaatc taaatgaaaa
    11461 tgaaattgaa actgctttga ataaaataca agatcctcag tttataaaaa gcttgaaaaa
    11521 tgttaagaac atctacggtg acggcaacag ttctagaaga ataacaaaaa cattgaatca
    11581 aatattgaat gatggggaag atattaagtg gattcaaaaa caaatagctt attaaaatat
    11641 actagtgatc catacattat tattggggct ggcggacacg caaaagtcat tattgaaacc
    11701 ttaagattag aaaataagtt aatatatgga ttttttgatg ataagcaaaa taaaatgcaa
    11761 gatctgaaat atcttgggaa aataaacgaa ttgaatagct gggcggatag caaaaaaaaa
    11821 atctataaat ttattgtagc tattggtgac tgtgtagtaa gaaaaaagat tataaaaaaa
    11881 ttgaatatgc caagtgagca atatggaata gctgttcatc caagtgctat agtggcaaaa
    11941 gaaatttcaa ttggttatgg aactgttatt tttgcgaatg ctgtaattaa cccagatgct
    12001 gtaattggag agcatgctat aataaacaca ggtagcattg ttgagcatga ttgtagaatt
    12061 aataactatg ttcatttatc tccaggtgta tgcttagcgg gtggagtaca tgtaggtgta
    12121 ggaactcaaa taggaattgg ttctcaatgt atccagatga agaaaattgg atcttggtgt
    12181 atgataggcg cagggagcac tattgttaag gatattccct cacattcctt agcttatggc
    12241 aatccagcta aaattaagaa agaaggaatt aattttgaat tctagaattt tattatcaag
    12301 tcctcatatg ggaggaacag aagaaaaata tgttgctaag gcttttaaag ataattggat
    12361 agcgccatta ggtgaaaatg tggataaatt tgaagaaagt attacaaaat atactggttc
    12421 taagggcgga gcttctgcgt taagttcagg tacagctgcc atacatcttg ccttaagact
    12481 gcttaatgtt ggaaaaaacg atattgtctt tgctccttca tttactttta tagctacagt
    12541 aaatcctatt ttatatcaag gggctgtacc agtgttcatt gactcagaac ctaatacatg
    12601 gaatatgagc cctgttgcac tagagagcgc attagaagaa gctgaaagaa acaaccaatt
    12661 acctaaggca atcatcgtag tgaatttata tggtcaaatg gctgattatg aacgaatttt
    12721 agctattgca aaccaattta atgttccagt gatagaagat gcagcggaat cgttaggttc
    12781 tacttataag ggaatttcgt caggcttatt tgggacaatt gggatctatt catttaacgg
    12841 taataagatc atcacaacct caggtggagg agctctagtg tctagtgata aaaaatatgt
    12901 tgagcattca agatttttag caacacaagc aagagatcaa gcaccgtatt atcaacatag
    12961 cgaaataggt tataattacc gtctaagcaa tatttctgcc ggtatcggac gtggacaaat
    13021 ggaagtattg aatgatagag tagctaaacg aagagaaatt ttcaatcgat ataaggaagc
    13081 tttttctgga attgatagaa ttgaaatgat gccagaagtg gatggcatgg tgccaaatcg
    13141 ttggttgtct actttaacga tcaatgatta taattctatt gatcaagtag ttaacgtaat
    13201 aaataaacta aatgaaaaaa acattgaaac aagagctttg tggaaaccac tacatttgca
    13261 accagtattt caaggggtaa aaatgtatta ccatgataat aatcttagtg tgtcagaaaa
    13321 gttatttaat agcggcttat gcttaccttc tggaagtaat atgacagata gtgaacaaga
    13381 atttgttatt gatgagttta aaaaaatatt caagtaggtg tgatatttta tgaacatagg
    13441 aattattggt ttaggttcca tggggaaaag aagacttaga ctcattcaag aacactttaa
    13501 tgatatttta ctatgtggtg ttgatactaa tgaggcgaga cgaaaggaag ttgaaaagga
    13561 atttggaata ccaacttata atagtctaac agaggcaaaa aatttgtttg aaataaattc
    13621 agtttttgtt tgtacatccc ctataaccca tgaatttatt ataaaagagg ctttaaattt
    13681 agattgtaat atctttacgg aaatcaattt attaaatgaa tattatgatg aaataatcga
    13741 agtagctaaa aagaaagata gattacttta tctatcttct acatttttga agagaaaaga
    13801 aattcaatat attaagtcta aagtgacgca taataaaaaa atttcttatc aataccatgt
    13861 aggacagtat ttacccgact ggcatccttg ggaagattat cgcaattttt ttgtttcaaa
    13921 caaaaaaact aatgggtgta gagaaatatt cgctattgaa ttaccttgga ttatagatac
    13981 atttgggaaa gttaaatcgt ttactgtaat gacccagaaa ttatccaatc ttgatattga
    14041 ttattcggac agtttcactc ttattattga gcatgaaact ggtatagttg gaactttaag
    14101 tgtagatgtt gtttcaagag tagctaaaag aaatttaact ataattggtg aaaagatttt
    14161 aatagaatgg gaaggtaacc cggattctct attttcatgg aatgaagaaa cttctagtat
    14221 gacagatatt caattgtacg atgaggttat gcatgataat aattattcac atactattat
    14281 tgaagatgca tatttagagg agattaaaga atttttcacg cttttggaaa agaaaatgga
    14341 accccaatat acttttgaaa aagataagta tattattaac ttaattaacg acattgaggt
    14401 aaattaatga tgaaagtaat tttttttggg ttagggtcaa ttggaaagag acatctaaaa
    14461 aatctaataa gctatggaaa aaagaattct attaattttg atataacagc ttatagtagc
    14521 agtggaaaaa aagagtttga agaaataacg tatattcaaa atagagacga tttggataca
    14581 cattatgata tagcttttat tacaaatccg acttttaagc atctggaaac actaaatgta
    14641 attgttgaaa aagttgatta catattttta gaaaaacctg ctttttctga gagtattgat
    14701 cttactcaat ataattatga ttacaaaaat atttatgttg ctgctccact gaggtataaa
    14761 aatatcatgg aagttgttcg taatagtatt caaagtaaaa aagtatattc tgtaagagct
    14821 atttgttcta cttatcttcc tgattggaga aaaggtactg attatagaaa taattattct
    14881 gcctttaaat ctatgggggg aggagtagaa ttagactgta tacatgaatt ggattatatt
    14941 ataaacctat ttggtttccc taaatcagta aaaaaacagt ttggtaaata ttcgaatctt
    15001 gaaattaaca gtaatgattt agcaacatat atattgagat acgatgataa aattatagaa
    15061 attcatttag attattttgg aagagttcct acaagaaaat ttcaattgtt tactttagat
    15121 gaatgtatca atgttgactt attaaataat aaaataagtt ttgaagaaaa cattgttaaa
    15181 gaaatgcctg aatctgctaa tgatatgtat gagaaggagt tgaaatattt ctttgaaaac
    15241 gtagtaacag gcaaagaaaa ctggaatgat ttatatcatg caaacgaagt attgaaaata
    15301 gctgaggaga aataaatgga aattttattt actatttgtg gtagagctgg gtctaagggg
    15361 tttaaaaata aaaatttgaa atatttggca ggaaagcccc tagtccattt cgctttagca
    15421 atgatagata tctatcaaca aaaacatcct gaacataatt gcacgacttg tttgaatacg
    15481 gacagtaatg agttagtaga attgacgact aagttaaatc cgtctgtgaa aattgtagaa
    15541 cgtaaacctg aattagctac agatactgta gggaaaattg aagtgatacg tgattcattc
    15601 ttacaactag aaagagaaga taatatattt gatttaatta tagatttaga tttgacttca
    15661 cctttacgtg aagtttctaa tcttgaagaa ttaatagatg aacatctaaa aaatttagat
    15721 aaagacgtct acttttcagt tgtttctgca agacgtaatc cctattttaa tatggtaaaa
    15781 agaattgaaa atgaagttac tatagttaat aaatcaagat acacatctag gcaacagaca
    15841 cctgaagttt ttgaaatgaa tgcctcaatg tattctttta aacctgaatt tctaaaaaaa
    15901 agtaattata tttttgatgg gcaatgtggg ataataaaaa tgagagatta tctaatttta
    15961 gatattgata gtgaagaaga ttttaaatgg ttagaatttt tgtttcctaa atttttagaa
    16021 gattcttcgg agcttcaaga tatctataat tatttatatc ggaggtaaaa ggatgagctg
    16081 ttatcttatc accggtgggg ctggcttcat tggttctacc ttagccaatc atttaggaga
    16141 agaacatgtg gtaatcgtcg tcgatgactt atcaatggga aaagtagaaa atcttgatat
    16201 gacgaaaaat atcactttta ttgagggaga tgtcgctgag aaatccttga tggaagagat
    16261 catgaaagct aataaatttg attatatctt tcatttagca gcagttgcta gtgtggcaga
    16321 ttcagttgcc cgaccagtag aaacacatcg tgtgaatttt gaaagtgtat taatgatttt
    16381 agaattgatc cgcaagtatc aacctgattt aaaacggatc gtgtttagtt cttcagcggc
    16441 tgtttatggg gatgaaccga ctttaccaaa aaaagaagag tccgtgattc gcccattgac
    16501 gccttatgcg gttgataaat tcgctgcaga acaatatgtg ctagattatt gtcatttata
    16561 tgatgtaccc ggtagcgcag ttcgtttttt caatgtctat ggtccaaatc aaaatccgaa
    16621 ttctccatac agtggtgtga tttctattct cgtagatcgc tataagaaac aaatcgtagg
    16681 agaagcaact tcatttacat tatttggtga tggaagccag tctagagact ttgtttatat
    16741 agatgatgta atccaagcat tacttttagt tgcgaatgag gaagctgcac tggggaaaca
    16801 attcaatgtt ggaacgggta aagcaaccac acttttggaa ttgattcatg caatcaatga
    16861 aattctcggt gtagaattga cacttgaata caaagaagag cgttcgggtg atatccatga
    16921 ctctctagca gatattacta agatccagtc aattggctat caaccgaaat atggtatttt
    16981 aagtggaatg actaattatt tgaaaactga aatcaattaa aacatactaa gataagatta
    17041 gagggtaaat tcaggctctt tgtcaataag gactgatgag ttttgtaaaa tcaaatctgg
    17101 gatagaa
//
LOCUS       DACBZK010000056        17007 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.058, whole genome shotgun sequence.
ACCESSION   DACBZK010000056 DACBZK010000000
VERSION     DACBZK010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.058"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..127)
                     /locus_tag="IVD66_001987"
     CDS             complement(<1..127)
                     /locus_tag="IVD66_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HAP6146191.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(231..542)
                     /locus_tag="IVD66_001988"
     CDS             complement(231..542)
                     /locus_tag="IVD66_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP6146192.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(544..741)
                     /locus_tag="IVD66_001989"
     CDS             complement(544..741)
                     /locus_tag="IVD66_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterocin"
                     /protein_id="HAP6146193.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1135..2862)
                     /locus_tag="IVD66_001990"
     CDS             complement(1135..2862)
                     /locus_tag="IVD66_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP6146194.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2855..4048)
                     /locus_tag="IVD66_001991"
     CDS             complement(2855..4048)
                     /locus_tag="IVD66_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP6146195.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4235..4879)
                     /locus_tag="IVD66_001992"
     CDS             complement(4235..4879)
                     /locus_tag="IVD66_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6146196.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4973..5107)
                     /locus_tag="IVD66_001993"
     CDS             complement(4973..5107)
                     /locus_tag="IVD66_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HAP6146197.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5109..7241)
                     /gene="feoB"
                     /locus_tag="IVD66_001994"
     CDS             complement(5109..7241)
                     /gene="feoB"
                     /locus_tag="IVD66_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HAP6146198.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFFMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7238..7711)
                     /locus_tag="IVD66_001995"
     CDS             complement(7238..7711)
                     /locus_tag="IVD66_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAP6146199.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8112..8336
                     /gene="nrdH"
                     /locus_tag="IVD66_001996"
     CDS             8112..8336
                     /gene="nrdH"
                     /locus_tag="IVD66_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HAP6146200.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8495..10654
                     /gene="nrdE"
                     /locus_tag="IVD66_001997"
     CDS             8495..10654
                     /gene="nrdE"
                     /locus_tag="IVD66_001997"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HAP6146201.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10704..11669
                     /gene="nrdF"
                     /locus_tag="IVD66_001998"
     CDS             10704..11669
                     /gene="nrdF"
                     /locus_tag="IVD66_001998"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HAP6146202.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11758..12897)
                     /locus_tag="IVD66_001999"
     CDS             complement(11758..12897)
                     /locus_tag="IVD66_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP6146203.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13206..13919)
                     /locus_tag="IVD66_002000"
     CDS             complement(13206..13919)
                     /locus_tag="IVD66_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HAP6146204.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14173..14874)
                     /gene="nagB"
                     /locus_tag="IVD66_002001"
     CDS             complement(14173..14874)
                     /gene="nagB"
                     /locus_tag="IVD66_002001"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HAP6146205.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15107..16639
                     /locus_tag="IVD66_002002"
     CDS             15107..16639
                     /locus_tag="IVD66_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP6146206.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16830..>17007)
                     /locus_tag="IVD66_002003"
     CDS             complement(16830..>17007)
                     /locus_tag="IVD66_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6146207.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5280 a         3494 c         2910 g         5323 t
ORIGIN      
        1 atgaaaaaac acattccact aaatttgatg ccggttttcc ttgaggtttt gttccagcac
       61 ctcctttaat ttttttaagc tcttgatctg aacattgttt agcatttagt ctattttttt
      121 cttccattac gattccccct acaaactata aatactttta tgtcactgat tcaatatacc
      181 tatttttcta atcaaaaaat tttgagacat atttaatatt ataagtatca ttaaaattga
      241 gatttatctc cataatctgc tcgatataaa ccatttattc cagcagttct tccaatttca
      301 ctcaaatttc ttattaattc ctcttgatat tcagtgaatc ttattttatt agtataagca
      361 gtaaaatata gataattcac caatctattt attaaaggac tgggatctaa ttcatatttt
      421 tgtttttcta attttaaata taccttttgt aaaacctcaa gaatatcaga atatttagga
      481 tctttactta tagatatatc attatataat tcatgaacaa tttgcttagc attttttttc
      541 attttagcac ttccctggaa ttgctccacc taaaaaacca cctatagaca ttcctgcaat
      601 acaagtagtt gccttggccc aatcgaccgt acatttattt ttagtgcaat acactccatt
      661 tccataatat tttccactat gagtggtacc cccatagata agttgtgtct ctttaataga
      721 caaaattttt aaatgtttca taatctaatc acccctaaat taatgttttt agactattat
      781 tctaacattc attaaatttc aaaaaacaat tccttcttga aacgtagcaa aataattcct
      841 gaataagaat ttaatcactt ttaagtatat aaactatgta tattctttaa tattttttga
      901 gaatgcactt cgtacataat aaactttaat cacattagtc tttcatacct acgatcgatc
      961 tctttgactc gcacccataa attcataata gtttgtcggc gtctttgaac gtttcgaaga
     1021 tgagctacgc attctctttt tttatagaca aaaaagatag agacgaacat ggagcttcca
     1081 aatttggata tttgatccaa ttttggaagc tccatttatt tcgtgtctgt ctttttattt
     1141 tttccagctt tcgactaatt cttggttctc tttgatccag tcttttgctg cttgctgtgg
     1201 atcttttcca ttgttgattt ccaacataac tttttccata tctttttctg accaatggaa
     1261 attgtctaat actttgtaag cttctggctg gtcttctttc aatccttttc gaaccatcgt
     1321 atggatctgc tcttcgcttc ccattccgtt ttcaggatct tctaagtatt tcagatcata
     1381 tttggcaaac atccaatgag gtgtccatcc tgtaactaca attggttcgt gttttttgat
     1441 cgcttgacct agtgcaacgg tcattgctcc tgaagaagat gtctctactt tccagtcttt
     1501 caagttgtca tatttttgga tcgtgttttc agcagccgta actacaccag ctcctggctc
     1561 gattcctatg attttcttac ctgcctgatc ggttaactca tcgatcgaat ttacatccat
     1621 gtaggctggc actgctaaac caacttttgc tcctgtcaaa ttggcaccta ggtcttcgac
     1681 ttgatcttta tattgtgcat attgtgaacc atgagtttta ggtagccaag ctgaaaccat
     1741 ggcatctgac tcgccatttg aaacagattt ccacatgatt gaattatcta atggcgtcat
     1801 cgttacatca tagcccattt gtttcaatac ttcaccgact acatttgttg aagcaacttc
     1861 tgtatcccat tcaacataag ataagttgat acgttttgtt tctttggcag atgaaaaact
     1921 ccctatacca atcgcaccta agatcactac tactacagca ccaatgatca gtccttgacg
     1981 ttttttactt ttctgtgttg ttgctcctgc agctttttta ttgtttggct ggttcaaatg
     2041 ctgtgtaaaa cggtcaatga tgattgctaa gataactaat gcaaccccgt tgacaaatcc
     2101 attcccgact tgtgctcttt gcaatgctga taatacgccg cgtcctaagc cgggtgcacc
     2161 gatcatagag gcaataacga ccattgaaag tgacagcatt gttgtttgat tgatccctgc
     2221 catgatcgta cttttagcta aaggcaattc tagtttgaat agtttttgac gacttgtgct
     2281 cccgaatgaa tcagaagctt ctactaattc tttaggaact tgtcgaatcc ctaaattcgt
     2341 aaaacgaacg gttggtggca gagcaaagat gactgaggca aatacccctg gaaccatccc
     2401 gataccgaaa aatgcaactg ctggaatcaa ataaacgaat cctggcattg tctgcataaa
     2461 gtcaaggatc ggtttgataa tactttgggc tttactgctt tttgccatca agatccctaa
     2521 tggtacccca atgatgatcg agatcacact agataaaaga acaagtgtga cagtattcat
     2581 caaatcattc catagacctt ggttataaat aaaccataga ccgattaatg tgaacaacgt
     2641 aagtcctgga cgtttcttag aaataaagaa agctgctacc gtcaataaca agataaacaa
     2701 aggagctgga atcactaaca gtaaatttgt aatccccgac atcactgcct gtccaatcgt
     2761 ttgtaaaaat gaaaataggc cagaaaaagt tgtcgtaaac cattctgtga tattttctac
     2821 ccagtttgcc actggtaatt gatagttcaa tagattattc atgttcactc acctcgcttg
     2881 tttctgctaa tgcttcaatc acactacctc ggatgacgac accttttaat tttccatcct
     2941 ctacaactgc aagtggagtc ggtgagtcat aaataatatt gaaaatatca cttaccacca
     3001 tgtctttccc aatcaccgtc acattttcat ctaggaagtc gatcaatgga cgtttttgct
     3061 tcctagcttc taacgcttga tctgcagtga tgatcccttt caggtgtctc tttctgtcaa
     3121 cagccatcag catgctgact tcttcattac gcatccttgt caatgcaacg tttggtccat
     3181 cagattcgat attcgtcgtc aatgcaggta ccatgatgtt ttgagccgta agcactttgg
     3241 aacgatcgac ttcttccaca aattcacgta cataatcatt tgctggattg gtcaatattt
     3301 cttcacctgt tccgatctgc atgatttcgc cgtctttcat caaggcgatt ctgtccccaa
     3361 tccgtaaagc ttcattcaaa tcatgggtaa tgaaaataat cgttttttga acattggctt
     3421 gcaggtccag taattcgtct tgcatttctc gccggatcag cggatcaaga gccgagaacg
     3481 cttcgtccat cagcaagatc tcaggatcat ttgctaaagc tctggctagg ccaacccgtt
     3541 gttgcatccc accagataac tgactaggat attggtcttt aaatgaaagc aaactagaat
     3601 tttctaatgc tttttctgct ttttcttgtc gttcttcttt aggtacacca cggacttcta
     3661 acccgtattc tgtattttcc aagatcgttc gatgtggaaa cagaccgaag ttttggaaaa
     3721 ccatattgat tttatgacga cggacttctc gcaattcttc tttgcttaac ttcgatacat
     3781 cttctccatc aatatagata ctgcccgaag ttggctcaat cagacgattc aatagacgga
     3841 tcaatgtgga tttcccactc ccggaaagcc ccatgatcac gaagatttct ccttctttta
     3901 cgtcaaaatt cacgtcatac acaccaaccg ttgcaccggt tttctttaaa atctccgttt
     3961 tcggctggtg atcattcatc atatctaaag cggcttgtgt ctttttacca aatatctttg
     4021 ttaaatgttt tacttctact tttaccaaac aaattctcct tttttatgta aattcatttt
     4081 tctttctgaa aaaagtgacc acactatgtt aacatcatgt agtcactttg tcaaaaatga
     4141 aagaaatttg cttgtccaaa ctgaaaaaaa cttggctaaa tctttgtaaa taaaaggttt
     4201 agccaagtta atattttttt aatatttcac acaatcattc tgcaagctga tgctccgggt
     4261 aaaaaaagtt tgtcatacgc tgtagtgtat attcatttcc aataaaatga acgatgtccc
     4321 ctgccgtaaa tttagcatag gggccaggtg aaacaagcag ttcttcatta tgagaaattg
     4381 cgataactgt ggcgccagtc gcctgccaga tattcaactc gctaattgaa cggtccagat
     4441 gcattgcttt ttctgataaa gataattcaa acggaagtaa aggattcatc ttatgtattc
     4501 gcttcgtttg attgaccagc tgatccaata attgagaaaa atgattcagc tcatcttgtt
     4561 gcttctccac acttgccatg atttctgctt ttgtatcttg gatggattgt acatcttgat
     4621 attgcaatag gaaatctttt gctttttcct tcgaagcaac aaatgcccca cttccatgcc
     4681 gtacttccat gattccaaga tctaccagca cattgatagc cttgcgggta gtctcaggag
     4741 aagcattgta cgtactggca agtgttgagc gggcatggat cttctcaccc actttatatc
     4801 ggttttcaac gatacgttcg gctaaatcaa cagcaatctg ctggtagcgc gggcggacga
     4861 tttttttctt tccagacatt ttctttcctc tttctttttt tactttccct catcttacta
     4921 tgctctagca aaataagcaa aaaaggggag aatagcctct tgcaacgact gatcatcgct
     4981 tgatctgttc cttttttact gggcaagctg tttgacagtc atcacaattc ttaccggatt
     5041 ttaaacgagt atagacaatt gcgcctgcac ttccaaagat taacacactt aataagaatg
     5101 tcgccatcct attcctctcc ttctaatgac aatatagtat aaaactggtt cttggatttt
     5161 ggctgacgga acaaaacata aacgagtcct atcatcagta aaatagcaag atacgtccct
     5221 aacgctacct gtccaccctc caataagtgt cccaactgat aaatcacaaa actaactaaa
     5281 taagctaaac cgcattgata gcctatggcg atccaagtcc atttcttggc attcatttcc
     5341 cgatggatag ccccaattgc cgcaaaacaa ggcgcacaaa gtaaattgaa ggctaacaat
     5401 gaataagctg ctgcgggagt atatgtgtgt tgtagcactt gccagatttc tctgccattt
     5461 tcggatactt ccgcatgacc aaacaaaata ccaaatgtgc caataatatt ttctttagcg
     5521 accaatcctg taatcgctgc gactgttcct tgccagtttc cccaaccaag cggctgaaaa
     5581 acaactgcca ggattcgccc gaaaaaggct aagatacttt ggtcttcaga aacaggttga
     5641 gcataaaaat tataagaaga gctgaaccag atcacgatac tagaaacaaa gataatcgtt
     5701 cctgcttttt taacaaaaga cttgctgcgg tcataggttt gtcttaggac cgctgaccat
     5761 tgaggaaaat gatatgcggg caattccatg ataaaaggag ctgtatctcc agcaaacaaa
     5821 cgtgtttttt tcaagctgat tccagagaaa ataattgcag tcataccaag aaaataggca
     5881 gaaggagcta cccaagattg atgaggaaaa aaggcccctg ctactaaggc aataatcggc
     5941 aactttgcag aacaaggcat gaaggttgtg accatgatcg tcaaacgacg atcttgctcg
     6001 ttttcaatcg tgcgactggc catgacgcct ggcactccac atcctgtagc aatcagcata
     6061 ggaatgaagg attttcctga aagaccgaat ttcctgaaaa gtcgatccat gaaaaaagcg
     6121 atcctcgcca tatatccgca gtcttccaga aagctcaagc ataaaaacaa tataatcaat
     6181 tgcggtagaa atcctaacac tgctcccacg cctgcgatga tgccgttcaa gatcagctcc
     6241 tgcatccatc ccgctacttg ccattcagct aacaatctgc caacatgttc tggtaaccat
     6301 gtaccaaaca atgtgtcatt gatccaatct gtccccattg ttcctactgt ttgaatagcc
     6361 agataataga tcagccacat cacaaatgcg aagatcggca aggctaacca acgattcgtt
     6421 gcaatctgat cgattttgtc actcatcgat aattggaaag aatcatttga cacaacacag
     6481 agtgtacata gttgggtaat aaattcataa cgttcattga ccagaatcgt ctcactatcg
     6541 tcgtccaata gtttctctgt taactggatc agttgctcga tctctttttg ctgagaaact
     6601 gctatctcgt aatcctctct taccttctga tctcgttcaa aatatttcat tgcataccag
     6661 cgtttcttgc cgctttgttc tcctagtaca tcttcaattt catgtaaagc tgcttctaaa
     6721 cgtggatcat atgtacaggg aacaggaata gaaggccgct tttttgcaga ctcctgaatc
     6781 ttttcgatta gtttttcgat tccttgcttt ttcaatacgc tgattggtaa aactggtaca
     6841 ccaagaccat aggaaagctt ttctagattg attttttttc cttctttttt gatgacatcc
     6901 atcatattca gaccaatgat cataggaatg tctaaatcca ataactgcgt agttaaataa
     6961 agatttcgtt ctaaattggt agcatcaata atgttgatga tcagttcagg ctgttcctga
     7021 accaaataat ctcttgcaat cacttcttct ggtgtataag gagacaaaga atagatgccg
     7081 ggtaggtcct gaatatgaat gttcggattt tttttcaacg atccttcttt tttttctact
     7141 gttacgcccg gccaattccc tacatattga ttcgaaccag tcaagagatt gaacaagcta
     7201 gttttcccgc tgtttggatt tccgactaac gcgatattca ttctttttcc tccctttgta
     7261 tcaagattag ttcggcctct gactttcgta acgtcagttc ataccctcgc actgtcagtt
     7321 cgattggatc tcccagaggg gctagttttc ggataactat ttttacattt cgcgtcaatc
     7381 ccatatccat taaccgtcgc ttcactgcgc cttgtccgtg gattgctacg acgatcccag
     7441 tctctcctgc ttttaattga tcaagagaag tccagctttc agaggaagca gtctttttat
     7501 tgacaaagat ttgacctagt atttcccgac ttactgccac tcgatgactt tttaccagta
     7561 aaatggcatt gttgcctgat aaattgacga cgacgatttt acttccggca acgatcccga
     7621 tattttgcaa atggcgtttt gttttttctt ctgtttcgat tcgttcgact tgataaacga
     7681 aattctgctt tgcctgcgct aaggtctgca tattgattcc tctcttgtga aataaatcat
     7741 gtattaaaat cattcattat atgttctaat tttcttacgt gttacgcaaa taaatgagaa
     7801 tcattctcac atagaatact ctcggtaatt gagaatgtca attatacttg tgatattatg
     7861 agcgaatctt tagtattgat agataaaaat gagaaaaaaa tatttcttca tagttttcca
     7921 caattttttc tctattaaat ttgctatttt cccacacgat acttgttttc agctcttttt
     7981 tcaaaaacac aaaacttagt attccacagt ttccacaaca caatatgtag tgtttgttgt
     8041 ttgacttttt tactaagagt tttatactat ctattataga taataagaat gtgttagagg
     8101 aggcactcac catgaacgta aaaatctttt ctaaaaataa ttgtatgcaa tgtaagatgg
     8161 tcaaacggtt tttaacagaa aatcaaattg cttttgaaga agtcaatatc gatgaacagc
     8221 ctgaagcagt agactggttg aaagcacaag gattccaaag tgttcctgtc attacttctg
     8281 atgcagaaac agttatcgga ttccgtcctg atcagttgcg taaacttgcc agctaacatg
     8341 actaaaagaa tcaaaacgtg atacatggat ttgaagggct tgagacagca ccagtttttg
     8401 tcgcaaactt ccaaatcctt ttttaaagct taaaaacaat gcaatgattt gcaatcaagc
     8461 atcatcaaat acgaaatgaa ggttgggcgt acgtatgagt cttaaaaatt tacaagatgt
     8521 cagttatttc aagctgaata atgaaatcaa tcggccagtc aatggtcaaa tccctttgaa
     8581 taaggataaa gaagctttag ttgccttttt tgaggaaaat gtcaaaccaa atacgatgac
     8641 ttttccatct attatggaaa aaatcaatta cttgatcgat caagaatata tagaagcaga
     8701 attcattcaa ttgtattcac catcatttat tgaaaagcta tatcaatttt tggacgagca
     8761 acatttttct ttcaaatctt ttatggctgc ttacaaattt tattctcaat atgcgttgaa
     8821 aaccaacgac ggttccgctt atctggaaac ttatgaagat cgagtagcct tcaatgcgct
     8881 ttactttgcg aacggggatg aagaattagc acttgctctt gcagacgaaa tgatccatca
     8941 acgatatcag ccagctacac cttctttctt gaatgctgga cgtaaacgtc ggggcgaatt
     9001 ggtgtcttgt ttcttgactc aagtcactga cgatatgaac tctatcgggc gctcaatcaa
     9061 ctctgctttg caattgtccc gtattggtgg cggcgtaggg attactttat caaatcttcg
     9121 tgaagccggc gctcctatca aaggatatga gggtgctgca agtggtgtcg ttccagtcat
     9181 gaaattattc gaagatagtt tcagctattc taatcaatta ggtcagcgtc aaggagctgg
     9241 cgtggtttat ttgaacgttt tccatccaga cattattgct ttcctttcag caaaaaaaga
     9301 aaatgcagat gaaaagattc gcgtaaaaac tctttctctt ggcgtgatcg tacctgataa
     9361 attttatgaa ttgacacgta aaaacgaaga tatgtattta tttagtccat atagtgtcga
     9421 aaaagaatat ggtgtcccat tctcttatgt aaatattaca gctgagtatg atcatctagt
     9481 tgcaaatcca aacattcgca aacaaaaaat caaagcgcgt gatcttgaaa atgaaatctc
     9541 aaaattacaa caagaatctg gctatcctta cgtaatcaat attgatacag cgaaccgcga
     9601 gaatccaatc gatggcaaga tcatcatgag taatttatgt tcagagattt tacaagttca
     9661 aacgccttct gtgattaacg gcaaacagga atatgaagta ttaggaacag atatctcatg
     9721 taacttaggc tcgacaaata tcgtgaattt gatgcaaagc cctaactttg gtcaatctgt
     9781 gcgtacgatg actcgtgcat tgacatttat tacagatgca tctgatatcg atgtcgtacc
     9841 accgatccaa aacggaaata agctgaatca tacgattgga ttaggtgcca tgggcttaca
     9901 cacttatctt gcaaaagaac aaatggaata tggctcagag gattcattag actttacaaa
     9961 tatttacttc atgctgttga attattggac acttgttgaa agcaacaata tcgctcgtga
    10021 aagaaaacaa gttttccata attttgaaaa atcagcttat gctgacggca cttatttcga
    10081 aaaatacgta actggagaat tccagccaaa atcagaaaaa gtcaaagcat tgtttgaagg
    10141 catttttatc ccaactgctg aagattggaa tgctttgaaa caagcagtaa tgaaagatgg
    10201 actgtatcat caaaatcgct tggcagtagc accaaatggc tcaatttcat atatcaacga
    10261 tacgagtgca agtattcatc ctatcactcg catgatcgaa gaacgccaag agaagaaaat
    10321 cggtaaaatt tattacccag cgccttatct atccaatgag acgattccgt attacacttc
    10381 tgcttatgat atggacatgc gtaaagtaat cgatgtttat gcaacggcac aacaacacgt
    10441 cgatcaaggc atgagtttga ctttattcat gcgttctgaa atcccagaag gcatttatga
    10501 atggaagaca acaacgaagc aaacgacacg tgatttgaat attttaagac attacgcttt
    10561 ccacaaagga atcaaatcca tttattacgt acgtaccttt actgatgatg cagaagaaat
    10621 cggaagcaat caatgtgaaa gctgcgtgat ctaatatcat agatagattc gcttattcat
    10681 attttaatta aaggagcatt ctcatgtcag aaacatatta tgaagcaata aactggaatg
    10741 aaattgaaga tatcattgat aaatccactt gggagaagct gacagagcaa ttttggctag
    10801 atacacgtat cccactttca aatgacctag atgattggcg tacattgtct caattggaaa
    10861 aagatacagt aggacatgta tttggcggtt tgacactgct agatactgtc caatctgaaa
    10921 gtggcatgga tcagttgcgt aaagatgtcc gcactcccca tgaagaagcc gttttgaaca
    10981 atattcaatt catggaatcc gttcatgcca aaagttattc ttctattttt agtacactga
    11041 atacgaaaaa agaaatcgaa gaaatttttg actggacaaa tacgaatcct tatctgcaaa
    11101 aaaaagctga gcgtatcaat gaaatctaca aacacggtac accgctagaa aagaaaattg
    11161 ccagcgtctt tttagaaaca ttcttgttct attcaggttt ttatactcct ctttattatt
    11221 taggaaacaa caaattggct aacgtagcag agatcatcaa actaatcatc cgagatgaat
    11281 ctgtacatgg aacctacatc ggttacaaat tccaattagg attcaacgag ttacctgaag
    11341 cagaacaaga aacgttaaaa gactggatgt acaatcttct ttatgagctt tacgaaaacg
    11401 aagaacgtta tacagaagaa ttatacgatc caatcggctg gacagaagaa gtcaagacat
    11461 tcctacgcta taatgccaac aaagcattga tgaacctagg gatggatcca ctctttccag
    11521 atactgccaa tgatgtcaac ccaatcgtaa tgaacgggat ttcaacaggc acaagcaacc
    11581 atgacttctt ctcacaagtc ggaaacggct atttgttagg tcatgtagaa gcgatgaaag
    11641 acgacgatta tttgattgga ttggaataag gatttatttt aattcaaaaa tttttcgaaa
    11701 aataaaaaga gtttagcgta cagatatttt aaatgtacac tgaactcttt tttatgctta
    11761 ttcacttgtt tcttccagca cttttggact gtctaacttt tccgaaacat gttccattct
    11821 tctcaataaa tagattttcc ggatatttaa tattatcgtc ttaatcactg catagacagg
    11881 tatgcaaatc agcatgccta atattcctgc gacacttcct gctccaatca ataccaagat
    11941 gatcgtcaaa ggatggatat tcattgattt cccaaataac aacggcttga tcaaatttcc
    12001 atctaattgt tggatcacta aaatcgacaa cgccatatac aaagcttgaa atggagagat
    12061 aaacaaaccg acaatgattg ctggtaccgc tccaataaaa gggccgacat acgggataat
    12121 attcgtgatt ccgcaaatga ccgcaagcaa caagctataa ggctgatcga atattctcat
    12181 tgccaaaaag ctcattacac caataatcaa agcatctaag atcgtactgc tgatataggc
    12241 agataatgtt tcgtttaatt cttttaccgt ttggcgtaac tctttacgaa tcgctttcgg
    12301 aaagaagtga gacaacgcat caataaattt gtgcccatcc ttgaacataa atagcaaaat
    12361 aaatggaacg gtaaataaca aaataaaaaa ttgcatcata aatgaaatga tttttgagac
    12421 acttgcagat aaactgacta atatgatatt gaacaaatta ctaagagata aatttgctga
    12481 tgctaattgt tcttccaaat tgaaattttt aaactcttcc cgctgcgcca attcatttaa
    12541 ccatttgctt gtttcatctg catacattgg caagctctgg gtcaattgaa ttgtctgttc
    12601 cattaactga ggcactacat tcatgacagt taaaacaact aaaatgatta cgaccaaaaa
    12661 cgtcaataaa aaaccgaaca ctctcgggat ccgatgcttt tcgagaaaaa caacgattgg
    12721 atcgaacata taatagataa aaccagcaac aagcaatggt aaaaaaattg ccgaaagcat
    12781 tttcaatatt ggactaaaaa tattcggcat ttgtaaaata aagtacacgc cgatgatcgt
    12841 gagtactagc tccactgtcc agaaaaataa ttttgattgt ttaaaacgtg attgcataca
    12901 tctcctccaa ggtcctttga tacttctatt ctatcattta acaaagagtt acgcgctgag
    12961 attttcattt gcttaaaaaa aacaaaaaaa ataaacatat tttaatgagt agacgagtac
    13021 ttaaacaaaa acacggtttg gagtagtgac aaaaattata ctgcagtccc tttttccaaa
    13081 taaacggtgt tcaaaagctt gcatcttcgt aataagccca gccaaacgaa aaatataagg
    13141 aactattttt atttggctgg gcttattact tgatgtagga catctatttt acaacctcag
    13201 atcatttatt gcgcaatact gactaaatgc aactttgtga tatttttgtg tacggacaac
    13261 tcctcgatca catcggcata agtgagccct tttggaagat caatcgtata gatatttttg
    13321 tacactcggt agtcatcaac gaattttacg tcaaaattca catcttcgat tacgatattt
    13381 ttctcttcaa aataatcggt aagaaaatct ttggtttctt ttctatggat aaattggatt
    13441 tctaactttt tagtcgtagg tacatggatc acgcgtttca ctactgtgag tgcaatagca
    13501 atcccgataa aactgatgat cgcaatggaa tagtaaccca tgccgatggc gatccctaat
    13561 ccagcaattg cccataaaga agcggcagtc gtaagtcccg tcaccgattg tttcgtgacg
    13621 atgatcgttc ccgcgcctaa gaaaccgaca ccactcacca cttgagcaat cagccttgct
    13681 tcatctgaac gaatcgttcc agcaagctgt ggatactcta aagcatctct taatgcacca
    13741 ctagcgatct caacttggat caatgcaatg atacatgctc ccatacaaac taaaatatgc
    13801 gtacgcatac ctgctggacg atttttatat tgtcgttcaa aaccgattgc tccgccaaat
    13861 agcatagcga tccctaaacg taaaataatc tctggaattg tcaataccat atcattcatc
    13921 taaacaccct ccagtccaat atatcatgtc tgaaaggagc agacaaaaaa agtgcaattt
    13981 ttacctctta cgaaaaaagg actgtgacaa aatttttgtc atagtccttt ttatgaataa
    14041 acggtgttca atcagctgac cctcggtatt actcaacaaa cggcaaaata tggggagcta
    14101 tttttccttt gtcttctcta atactcaggt caaaacgctg atttcacaac ctctttagcc
    14161 tactattgaa aattacaact tacttgctgc ttcttcatcg atgatcacaa caacattgtc
    14221 gtgattttgc aatacacttg ctggcaaatg attcgttaca ggtccttcaa tcatcccttt
    14281 gattgcatca gctttgcttt cgccaaatgc catcaagacg atttctttac ttttcataat
    14341 tgaaccgatt cccattgaaa cagcttttgt tggtacatct tctgctttat cgaagaatcg
    14401 tttgtttgca ttgattgttg attctgttaa gtcaactact gaagtcgttc cgtcaaatga
    14461 agcaccaggt tcattgaaac cgatatgtcc attttgcccg attcctaaga tttggatatc
    14521 gattggatgt gcatcgatga tttgatcata ctttttgcat gctgcttcca gatcttctgc
    14581 ttttccatct ggtacaaacg tttctttgaa tggtttttta tcaaataatt ggacatccat
    14641 gaaatgacgg tagctttgtt catctgaacc gcctagtcca acgtactcat ctaagtttac
    14701 agaagtcatt tcactgaaat ccaaatcgct tgaagtcatt tctttatata aagtaactgg
    14761 tgtgcttcct gttgccaatc ctaatacttt tgcacctttg ttcatacctt ctttgatgat
    14821 ttcaaatgct ttttttccgc cttcttcagc gttttttaca cgaatgattt ccatagtgat
    14881 tgctccttta tattttggta tagcccaatt atagcattct ttttttcttt ttacaataat
    14941 tagtatagac caaattgcat tttttcattt tcttgacaat aaataggaat ccgtgttagg
    15001 tttcataaga tggttcaatc aaacaatcca tgttgcatga aaaccaagca agtgattcac
    15061 tgtggacgct ttatgtctgc agttttttta tgaaaaagga gttattatga gtatactgac
    15121 attaaacaac attacccagc aatttggcga caaaatcctc tatgaaggtg tcgatctgca
    15181 attaaatgct ggcgaacatc ttgggctgat tggacaaaac ggagccggta aaagtacatt
    15241 gattaaaatc atcactggtg agatcttacc agatgacgga cagatccatt ggcaaaaaaa
    15301 tattcacaaa ggttacctcg atcaatatgt ggaagtcgat gaaacattaa caatcgaaga
    15361 atttctaaaa actgcgtacg caaaagaata cgaaaaggaa gaaaaaattg cttttcttta
    15421 ccaaacatat agcgagacct tcgatgattc cttgctggaa aaagctggga aactccaaac
    15481 ggaattagac caaggagtgt tttatcaaat cgacacctta gttgctgaga tgagcagcgg
    15541 gttggggatc gatgtcttag gtttagattc actgttgaaa aatctaagtg gtggacaacg
    15601 ttcaaaggtg attttagcaa aactactttt agaaaaccca gatgttctga tcttagatga
    15661 accaaccaat cacttagatg atcagcatat ccaatggctg acgcagtttc ttcaggattt
    15721 tgacggtgcg tatatcgtga tttcccatga ccaagaattt cttgatcaga tcaccaccca
    15781 tatcgcagac atcgagtttg gaaagattac taagtatact ggccatctaa aacaagcatt
    15841 gaaacaaaag gaacaaaatc gcgaaagcta tttgcgccaa tatcatgctc aacaaaaaca
    15901 aatcgaaaag accgaagctt atattcgaaa atacaaagcc ggttcccgat caacgatggc
    15961 aaaaagccga caaaaacaat tagataaaat cgaacggctg acgcctccag cttcagcaag
    16021 taaagctgtc tttgattttc cattctcgcc tattgtcacg acattagcag tggaaacaac
    16081 tgatttagtc atcggatatg atcgaccgct acttgcaccc atcaatttga ccatccgctt
    16141 tggtgaaaat attgccattc gaggcttcaa cgggattgga aaatctactt tattaaaaac
    16201 actgatcggt gagattgaaa aaataagtgg cgatttccac ttcccagata acacaaaaat
    16261 caattacttt tcacaagatc tgtactggga aaatccatta gaaacaccac tacaatattt
    16321 aagcagtcaa tttccaaaag cgactatcaa agaattacgt cgccaactag ctaaagcagg
    16381 gttagttaat caattagcaa gtgaacctct cactacatta agtggtgggg aacaaactaa
    16441 ggtgaaactt gcacagttga caatgaacca aggtaattta ctgattctcg atgaaccgac
    16501 gaaccatatc gatcaagaaa cgaaagaaag cttacaagac gggatacaga aatttccagg
    16561 aacagtaatc atcgtctctc atgaacaaga attttatcaa gatcttgtgc aacgagtcat
    16621 tgagattgaa ccaaaataaa cgtttgattg aatagttgaa aaaaaggagc tgtgacaaaa
    16681 gttttgtcac aactccttct tctgaataaa tggtggccaa ttagctgacc ttcggtatta
    16741 gctcaaaaaa cggcaaaata tgaggagcta tttttatttg gctattctta ttacttgatg
    16801 cagaacagct tttcacaacc tcttttcgtc tattttttat tttcgagatt tctctttcct
    16861 ttaaaaacaa ctgtttgaaa gaagaacgca catccttgaa aaacaagccc gctaaccgtt
    16921 acacctaacc agccatactg ctgccacatt gtcgtcccta gcaatgaacc agccgcacct
    16981 ccaataaagt acataaacat aaataca
//
LOCUS       DACBZK010000057        16903 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.059, whole genome shotgun sequence.
ACCESSION   DACBZK010000057 DACBZK010000000
VERSION     DACBZK010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16903
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.059"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..189)
                     /locus_tag="IVD66_002004"
     CDS             complement(<1..189)
                     /locus_tag="IVD66_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146208.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(199..1014)
                     /locus_tag="IVD66_002005"
     CDS             complement(199..1014)
                     /locus_tag="IVD66_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6146209.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1276..1719)
                     /locus_tag="IVD66_002006"
     CDS             complement(1276..1719)
                     /locus_tag="IVD66_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HAP6146210.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1853..2191)
                     /locus_tag="IVD66_002007"
     CDS             complement(1853..2191)
                     /locus_tag="IVD66_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP6146211.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2179..2556)
                     /locus_tag="IVD66_002008"
     CDS             complement(2179..2556)
                     /locus_tag="IVD66_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP6146212.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2780..3973
                     /locus_tag="IVD66_002009"
     CDS             2780..3973
                     /locus_tag="IVD66_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6146213.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4139..4561)
                     /locus_tag="IVD66_002010"
     CDS             complement(4139..4561)
                     /locus_tag="IVD66_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP6146214.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            4956..5150
                     /locus_tag="IVD66_002011"
     CDS             4956..5150
                     /locus_tag="IVD66_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146215.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            5147..5641
                     /locus_tag="IVD66_002012"
     CDS             5147..5641
                     /locus_tag="IVD66_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146216.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(5803..6975)
                     /locus_tag="IVD66_002013"
     CDS             complement(5803..6975)
                     /locus_tag="IVD66_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP6146217.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(7181..7996)
                     /locus_tag="IVD66_002014"
     CDS             complement(7181..7996)
                     /locus_tag="IVD66_002014"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP6146218.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNMI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(8146..8592)
                     /locus_tag="IVD66_002015"
     CDS             complement(8146..8592)
                     /locus_tag="IVD66_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HAP6146219.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(8589..9593)
                     /locus_tag="IVD66_002016"
     CDS             complement(8589..9593)
                     /locus_tag="IVD66_002016"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP6146220.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(9633..9962)
                     /locus_tag="IVD66_002017"
     CDS             complement(9633..9962)
                     /locus_tag="IVD66_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HAP6146221.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(10088..12415)
                     /locus_tag="IVD66_002018"
     CDS             complement(10088..12415)
                     /locus_tag="IVD66_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP6146222.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            complement(13258..13551)
                     /locus_tag="IVD66_002019"
     CDS             complement(13258..13551)
                     /locus_tag="IVD66_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HAP6146223.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(13954..15132)
                     /locus_tag="IVD66_002020"
     CDS             complement(13954..15132)
                     /locus_tag="IVD66_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6146224.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            complement(15236..15550)
                     /locus_tag="IVD66_002021"
     CDS             complement(15236..15550)
                     /locus_tag="IVD66_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6146225.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            15657..15872
                     /locus_tag="IVD66_002022"
     CDS             15657..15872
                     /locus_tag="IVD66_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146226.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTIKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(16172..16414)
                     /locus_tag="IVD66_002023"
     CDS             complement(16172..16414)
                     /locus_tag="IVD66_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6146227.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(16401..16829)
                     /locus_tag="IVD66_002024"
     CDS             complement(16401..16829)
                     /locus_tag="IVD66_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP6146228.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFLI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
BASE COUNT         4928 a         3271 c         2935 g         5769 t
ORIGIN      
        1 gcaacctgga ccaataaaaa gtaaagaaaa aataaaggaa aagacattcc ttccatctat
       61 cgacaaaagg aacgcagctg ctatatacaa gatattgaca caccaaaaac aaaggctact
      121 tgccaatgat tgatacaacc aataaaagaa ttccatataa acatttttgt caaaacgctg
      181 ctctttcata atcacctcct attccttcat tcctgatgaa gcgatccctt ctacaaaata
      241 tttttgcatc gctaaaaata taaaagcaac aggaagaaca gaaacaactg aggcagccat
      301 gattaatgcg tactctgcat caaatagccc aataaacatt ttcaacccta actggattgt
      361 tttattttcc gtagaagaca aataaatgaa tggccccata taatcgttcc atgtattaac
      421 gaatgtgatg atcgtcaaac tggcaatcgc cggttttgta agaggtaaaa tgatcttgcg
      481 atagattccc cactctgata agccatcgat ccgcgcactc tcacataaag aatctgggat
      541 actactgtag tattgcttca acaagaacac accaaaagca ttgaacgctt gtaatagcac
      601 caacgaccac aacgtatatg ttaaacccac ttttctcatc ataatgaact gcgggatcat
      661 ataagactgc caagggacag caatcgtgcc gatatatgct aaaaataaaa tatcgcgccc
      721 tttaaaattt agtttagaaa acccgtaagc agcaaaacta gaagtaaaca actgaatcaa
      781 cgtgatcaca acgcttaaaa aagctgtatt cttaaaaaat gtcactaaag gaatacgaga
      841 ccaaataacc agataattct ctaaatgcca agttttaggg atccattgaa tcggaatcgt
      901 gaacacttca ttatttgctt tgaatgaagc agaaaccatc cataaaaaag gaatgatcgt
      961 caataaagct aatacaatca gcagaatcat acccaaccat tgaataaagg gcatgttttt
     1021 tgaacgaatt tttgcttttt ttctttcatt tcgaacacct ccaaagttat aatcttcatt
     1081 tctttgtaat gattacaatc cagaacaacg gttattatag ctgattcatt tccgttcttc
     1141 ttatgtttgt aagcgcttat ttaacaagtt atgtaaatct ctttattttt tttgatttaa
     1201 aaatgaaaaa atacaaaagc aagactgtca tacgtctcgc ttttgtattg aaatttcttc
     1261 gattagagat acttattact gttcaaaagc ttctttgaaa cggtgaatca attcattgac
     1321 tacaggtgat aaaatccgat tctttttcca gactagcatg cagttcgttt caatcattgg
     1381 gtcaagcgga acgaatgtca ctcgctttga aagatgactt acagcacctt ctatgactaa
     1441 agcagcacct acctgattct caattagcgc aaatacattg aaaatcaaat tgtacgttcc
     1501 tgtgatcagc aactgctcct tttttatgcc taaccagtca gcaaacattc gctgtatttc
     1561 tggacgcttt gagatcaaaa gaggtacatt cgcaaagtct tcttttgtta tcacgtcttt
     1621 ttttgctaaa acagaatttt ctaaaatgag caatccccat ttttcctttc ttggtaacaa
     1681 aatcgtttcg tatttctctg tatctactgg atctagcaaa atcgctaaat ctaacaggct
     1741 tttttctagt cactccgtga tatcatcact tgttccgctg tggatatgaa attgaacgct
     1801 gggataatca cggatcaact tttctagtaa tagtgccaat gtattcgaat tatcagcttc
     1861 cacacagccg atcgtaaatc ggccgctgaa taattgtttt tttctgttct cgaattcttg
     1921 agtggtttga ttcgttaaat ctaaaatttc ttctgctcgg cttttttaga aaataacctg
     1981 cttctgtcaa gatcattttg cggttttcgc gtacaaacag ttctgttcct agttcctctt
     2041 ctaactcctt cagttgtcgg cttaaggttg gttgtgtaag atgtagaact tctgcggctt
     2101 gagagattgt tccttcttct gcaattgtcc aaaaatattt tagtaagcgt aactccatag
     2161 cgatgctcct tgattttttt acttgataca ttccatttta tttctagata acacacgatc
     2221 atatttcttg atttttcctt gtaaacgttc caaacactct tgcatttcag caatttcttt
     2281 cgtcaaaagt tcactttctt caatcaaaag cttacgccgc tcaaatacag ttgcttctcc
     2341 ttcgctagat aggcgaatat attcaatcaa agactcgatc gataatccgg catttcgcat
     2401 acagatcgta aagtcgaccc attttaggtc ttcttctgta taatcacgga ttccgccttt
     2461 tgtccgatta actggtggaa tcaacccgat tcgttcataa tagcgcaatg tatcggccga
     2521 aatgcccttt tcttcactga cttgtttgat attcatctga tcactctttc tcttaatttc
     2581 ttgccacttt acttatgtat tttatttatt ctacaacttt aagtgtactc caagtcaata
     2641 ctcatttcta ttaaaactaa gctggattat ctatatcggt tgtttgtgta ttatttcaaa
     2701 taaaaaagtc ttgttttttt attctttttt ggatatactt ttaacaattt agggaaattt
     2761 taggaaaagg ggtataaaaa tgacaacgta tcagcgaaag gtattattat cgacatcggc
     2821 gggaattgct ttagagaata tggatattat gtttttagct ttttcattat cttcaatgat
     2881 tacttctttt catattagtg gtacgcaagc gggtttcatt tcaacgatca ctaatttggg
     2941 gatgctcatt ggaggtattt tttttggcat catagctgat aaatatggac gtgtgaaagt
     3001 attttctcaa acggtccttc tgttttcgat tgcttcttta ttgatgtatt ttgcttcaaa
     3061 catctacttg gtttatctct ttcgctttat cgcaggtgta ggagcgggag gagaatacgg
     3121 ggcgtgtatg tccttgattt ccgaaagttt ttcaaaaaaa caaattggac gagcttcttc
     3181 ggttgctggt attggtgcgc aggtcggtgc ggctttggct gcgattttag ctgctgtgat
     3241 cattccaacg tttggttgga agatgttgta tgtcgtaggt gtactgccgg tgttgatggt
     3301 cttgttcatt cgtcgcggct tgactgaacc aaaggaattc aaatctgtac aatctgccga
     3361 aaagaaaacc aaacttagca gactgtttga atcaaaacat cttgcttggc aaacatgtgg
     3421 ccttagtatc atggtaactg tccaaattgc cggctatttt gggttaatga attggctgcc
     3481 ttcaattatg caaaatcgat tagggctttc ggtttctggg tcttcattgt ggatggtcag
     3541 tactatttta ggcatgtctt tggggatgat gacttttggc ataatcatgg ataaattggg
     3601 gcctaaacta gccttttctt tgtttttaat ttgttcatcc ttatctgtct atctacttgt
     3661 gttagcccat agccagtgga gtttggtagc agccgctgtg atagtcggct actttatcaa
     3721 tggcatgtat ggtggatatg gcgcagtgat tagtagtttg tatccaacag aaatccgcgc
     3781 gacggcgaat aatttcatta tgaaccttgg acgagctgtt ggtggttttt cttctatcgt
     3841 catcggtttc ttgatggatc attatagttt aactgccgta atcttgtttt tgagcggtat
     3901 ttacctagtc agtctgctgg tcttgacaac tcttactggt gttacagcat taagggaaag
     3961 cttgcagcat tgatagttga gtctgtaaat gacaagaaag aggtgtggca aaagcttgca
     4021 tctgcggtaa taagaccagc caaatcaaaa acatgagaca ctgtttccgt ttggctggtc
     4081 gtattacttg atgcagggca gctttttcaa ctgctaattt ccttctatct ggcggcgact
     4141 attctttgac gtccgtcatt tcaaagtact ttactaataa cttagcataa cgaaaaactg
     4201 tggatacact cgtatattga gcgtctgcat aatcttccaa atttttctca ggatgttgat
     4261 acatgaattc aatcaaatga taattatatg attttctgta gaaatgaaga taaataatgt
     4321 agattgggaa gttctcctgc ttttccatag aaaagcgccg attattctca ttcttcaaaa
     4381 tgaccttatc aggatatttt tggaacaatt cttctaaatc tgttagataa ttcaagatag
     4441 acttacttga taccttcaat tcgttttgta gttcttctat tgaacaccaa cgttctgttt
     4501 caagcagtaa atgaatcatt ttaattttct tttgagaaac ttttgttaaa aaagtctgca
     4561 tattttctcc tcctgtatct actttactat actacataca agaaaaaaaa cggatacaaa
     4621 tatcatattg tcacaccgtc aatagtgcat aaacctgtta ttatttctct ttttttccta
     4681 agtattctat tgatatgaat catttaatcg tttattatat aaatgtcaat aatctaataa
     4741 taaaataacg tacatatttt attattgcat acttaataac agaactatag caaaaaatcc
     4801 cgtgtatcaa cacgggatta gattaagttt cctcaatcac tattcataac acaattatta
     4861 taacaagtaa gtaaacaatt gaaaaggaca tttattgaaa acggttgttt tttacttaag
     4921 gaggaaattt agcgaaaaaa ttagttgcat tgtttttggt cgcaggaagt ttgttgagtg
     4981 ggtgtggtgc tactacgtct actactcaaa gcacaagttc agatcaggct tccagcagca
     5041 gtaccacgat ctccgaaagt acggcagatt catcgaaaga acaagaacaa attgaaaaga
     5101 aaaaagaaga gaaacaaaaa gcggaaaaag ctgcactaga aaaaaagtga cagaagcgga
     5161 atctgctttg tcacaagctg aagcaaatcc tacaaaagaa aactatgcaa ctgcttcagc
     5221 agctatccaa gcgctacctg aaaacaaaca agagttgaca agccgtcttg ctgcaattga
     5281 ttccacaatc aaagcaaaag aagcagaaga agaacggaaa aagcaagaag aaattgcacg
     5341 acaacaagca gaacaagcgc aacaagaagc aatcgcacag caacaagcag aacaggcgag
     5401 gcaagaagca atcgcacagc aacaagcaga acaggcgcga cagcaatcag cagctgaaca
     5461 ggcctctcag caggcacaag ccgcagctcc tgagcaaaat aatgaacaaa ctgtctatgt
     5521 cacaccgacc ggttcaaaat accatacaca taaatgtgga aatggtacgt atacccctgc
     5581 cactttaagc gaagctcaag ctcgtggttt aaccccttgc tccaaatgtt atggaaacta
     5641 attcaaaagt tatactataa taataaaatt cttctgaaac ataaaaaaat agaagatggc
     5701 gttccagata gtaaaccaaa aataacagtt tacacgtcca tttcgtcagc ttctctcttt
     5761 tttcatttag tctgttccct ctgctttttt ggacatcttc attcattctt tctcaatcaa
     5821 atagtacacc tctttttctt ttcgcagttt atatcttcct tttttcaatt tcattgaaaa
     5881 ctgtttcgaa tgtttatgtt ttacatggat tttaagcagg agctcctcat gttgcaagcg
     5941 atagttcctg ccttttaaat cagaaaatct cactagtccg tattcatcag aagctttcac
     6001 aaatggaact ttttctctag taatatagtg tttgccgttg agcgttttta cagaaaagac
     6061 cattccttcg attggtcgtc cgtttgtgtt ctttacataa aaagataaag gatagtttcg
     6121 cttagcgatg gccaaagaat ctaaataagc gatgagtagc caaactaagc cgattgatcc
     6181 aagtagtata ccgataaacc aaataaaaaa tttccatttt ttccattgat caattccttg
     6241 gatcgctttt tttgcctctt ttgcttgata aggaatacga tgccccgtca caagcagtcg
     6301 atgtgtattg accatataag gagtacaggt aagcaaagtc acgagatctc tgcctttttg
     6361 gatacccaaa gaatctactt catcaggtaa gaccacttgg attttttcta cttgatacgc
     6421 caatgtcttt ccattgatct ggatgaaaaa ctggtctcct tttttcaact taggcaaatc
     6481 tgtaaataat tttgcttctg ggagtccacg atgcccagaa agaacggcat gggtgttttt
     6541 cccgccagtc ggataagaac tttcttccaa taatgacgtt cctttttgca aaaatatttc
     6601 cgttgtctga tcgaatatag gtaagctgac attgattttt gggatttcga tgactccaag
     6661 catatgttcc ataaaaaagg cattactagg taaatctttt aatgcttttg catcaactgc
     6721 ttggttgaaa ctgcctatcc ctggtgatac gttttgctct gccaactgtt ggtttttctt
     6781 tgtcattttt tcctgctgtt tttttatttc ctctgaattc ttattcgatg cttgcttttg
     6841 ataatggatg atcatttgct gggcaagaaa atcattcagt gaatcttcta caaaaggata
     6901 agaaaagatc ccgatcccaa cgactaaaat gattgccatg aagatgtcca gtattcttat
     6961 tctgctttta ttcatcatgt ccacctattt tctaatatgt atatgaagag gttgtgaaat
     7021 cagcgccttg acctgagtat tagcgaagca aacggcaaaa tagttcctcc tattttgccg
     7081 tttgttgagc gaataccaag agaccgacca cttgtcacaa cctttctccc catttgaatc
     7141 actatcgttt atttatcgta tgatttttgt ttccaatagt ttaagcttct gtttcttgat
     7201 ggcgtttttt gaaatagatc actgctcctc caactaaagc agtacctacc aagatgaata
     7261 cgatgatccc cataccacca gttgaaggca agattccttt aggttggtta tcgatcgttg
     7321 tttcatcaga agttgttgga tcatcatcta ctgtaaattc agtgtacgca gcttcattct
     7381 taggtaatgc gtagccttct ggtgcttttg tttcttgaag gcagtatgcc ccttgtttca
     7441 gcccttcgat tgaaaatttc ccttctgaat cagaaatcaa tttcacttct tcccagtcag
     7501 aacctgtgac ttcatctgac caagcatatg ggtattctcc tgaggcaagg tttgctattt
     7561 ttttcattaa tttaacagtt ggatcttttg ctcttagaat agaaaattct gcatcggcta
     7621 atttttcttg cgtgttcaca tcttgtttga tgaagtggaa atcaccgtag ttttggacat
     7681 tttctacagt aatcatgtta tccgtagttg tattttcccg attgactaca ccgtttggat
     7741 tcccaagatt ggcttcatct gcgccatgga tgataccggt tgtttgttgc aattttccgt
     7801 tttttactat aaaagtagtt tctttttgtg gattggttaa ttgataacca tctggtgctt
     7861 ttgtttcaac taaagtataa ttgccgtcta ttaatccatt gacactgatg gatccttcag
     7921 tatcagttgt gaatgtcaac gctgactcag caggatcata gagagcgaca ccagtgtttt
     7981 catcaaaacc ggtcacgaat tgattctctg aatttttgat ctggaattgc gcccctgcta
     8041 acttatctac ccctgaaaag ttcccagctt tctggatttt gatattgctt tctttgatga
     8101 catttttagc atataggtga atcgtgtcta aaggtttgtc agggtctagg gtaagcttaa
     8161 cacgatattt ggcgacgttt cgacaccggg ctttggtgtt tctacaaaga cgtatacagc
     8221 atctttccca tcagatttac ctggaagagt caggttagct aatccttcac cagaagtcgt
     8281 tacacttgcg aagggtgtag cgtctgctgg aactgctgtg tctttacttg gatagtacgt
     8341 agcagtgatg tcatatacgt tgaattcaac gccgttcaac ggttcgctat tcggaaatgt
     8401 caattccgtt ccgttgttta tttgattttc tggtgctgaa gtgaatttca atttatgcaa
     8461 attaaccgta acattttctg gtgtaggtga tacggctgca gaaacctctg cagttcctag
     8521 gccgagaacg aaaggaagca gcatgatagc agttcctaaa aacgtccata tttttgtttt
     8581 gatgtttttc attttatttc cctcctattg tttccttttt gttgtttttt ataaaaccaa
     8641 gctgtccctg ttgaaaggac tagcaataac cctaaaattg agaaacctcc aagcatctct
     8701 tcgcttgttt ttggaaagct tcctccattt ttttcatttg atggaccatt tgtctgcatc
     8761 tgaactggcg tttttccatt attcgtcgga tttgcttttg gttcgttgat gatttccaat
     8821 ggtataggat gaagcggatc ataactgcct ttttcaactt caaagagaat ggttgattga
     8881 ctcaatatat atcctttagg cggtttaatc tccactagtt cgtaacttcc aaaagacaat
     8941 ccatggacag aaaatgttcc atctttactg gaagtaaaaa tcgttgctct tgaatcatct
     9001 ttggctaccc aatgatttat cccgttttct tgcgctaagt attggtcatt ttttttgact
     9061 agaaattgag catctgctag tttttgtttc gtttgccgat ccactttgac aaattgtttg
     9121 cctcctgttt ggatggcaag atgtgtttct actgtttgat tgtcagtcgt caaacgtaca
     9181 tcgttatcaa atgtcgtttt ttcactgttt tctttcaatg tcatttggta acggatcgtt
     9241 aatttttttc cagcaaacga actaagatct tttccagaat ctgataagac aaaaccatgt
     9301 tttatttttt gtgtgtgaaa tgtatgaatc ttgtctccac caatcaaaaa atcgatcgtt
     9361 tctggttcta gccataactg aggatcagct gtatctttga tcgtataggt tcctatctcg
     9421 ttgatgttct caggaattgt tacggtgatg agataaggga ctttatcccc atctgcaaaa
     9481 tctgtctgct tattctctac tgtttttgtt aatgtgagtg cagcaggtat tttttgttcg
     9541 ctctttggat acaagtggat ggtcgtcaat ttatgattag atgaatctgt cacaggaagc
     9601 acaacgacaa atggtgctga tttttctttt acttaatctg aagtctttat ttccgtaaat
     9661 cggtaaacag cgtcacgacc ttgctcatct ttgtccgatg cactaaaaga agcaatgccc
     9721 tcttcctcgt ctactgtttt tgtcacattt tctgccagta ttttttcact atcacttttt
     9781 tgtgctagtt ttctttgtgc gtcttccaca ctacttcctt ctgaccgcag cttgtaaaat
     9841 tcatccgaga catcatatat agcgaaagta acgccgttca acccttttac tccttgaaag
     9901 ttatccggga tatttattcc gtcgttttga ctgatacttg gcatcttatc gctttcgaac
     9961 attcgattat gcaaagtaaa tgtaataggt gattctctag ctgacacagt cggagaacct
    10021 ataaaaaaga ccagtaggat aaaaaagaga acagcaaata tatccacacg tacatttttt
    10081 gtttttttca tcgctgttca cctgcttttt tcttacgatg gataaaataa aagaagccag
    10141 aaaaaataaa gatcagtcct aaaaagacaa agggcagtag acctatccca cctgtcgaag
    10201 gaagcaagag agtcggattg atcgtcaact tagcggtatc tgttgcgata atcgtataat
    10261 tattgtttac acttccttcg cctaaactaa tcgttactat ttgtgatcca atatctgtcc
    10321 ggctgttaac tgttagggta taatccaatg attcgcctaa gacaacaccg gtaacgtgga
    10381 gatttccaac cgaaatcgag tgactttggg catcataatt aaaggcagcg tcatcgacag
    10441 taatcactgc gttagcttta tagatggtat aagttcctga tgtgttggct atatcagtaa
    10501 atgacaactt gggatttgct gctttgactt tgtctattcc gctattcgtt agtttaattg
    10561 tatagctgcc agcattaacc atattttttg ctgattgtgc atctgctgtg taatccatac
    10621 tgctaagtgc cacttgtact ggagtaagcg aactagtgac accctctgct agcttgacat
    10681 ggattgacgg gacacctgct tttccatcat atgtcttact gccactgagc tctaccgcac
    10741 cgctgatttg cttaatcgta tagacatcag atgtctgcac gatagtaaat aaatagtttg
    10801 ttctggcagc tagtttagct agtccgcttt ttgtcaattg ccaagacgta taggttccaa
    10861 tttcagtagg cgcagttact tcaactccct tttcattcat cgctttgaaa tcagttggat
    10921 tccatgtgat ttgatcaata ctgagatcat tgtttaaaag ggatgttgat tctgttttat
    10981 cattaaaggc atatttaacg atcggtacaa cagaaagacc atcatagtac ttactgccat
    11041 ttgcattgat tgatactgtt gcatttgtct tataatatag gatgacttca gaaatctgtt
    11101 ttccatttgc gtcctttacg attacatttc catttgtatc taaactagct aaaacactca
    11161 ttgctgattg gttctttgtt tctatcgctg aaacagctgt aaaggtatat ccgttgatag
    11221 taggcgtatt agtcgtcagg tcttgtgcag cacttccgta agtaagattc attattttag
    11281 aaggagcaat catctgtcca aaatagtctt gatacttaat agtgattggt gtttgtttgc
    11341 ctgtataggt caccgtatcg acgttacttt ctagggctgt gaaagaaccg tttgtttgtg
    11401 caaaagaata gcccgttact gctgttggag tgataaccac tttgtcaccc acatggattc
    11461 cagataatgt agtcccgtac gttccgattt ttgctgctcc accattgact gtataagaaa
    11521 aagttcctgt ccgattcgca ttgacctgaa ccgttgctgc ttgataggtt ggaaaatttg
    11581 aaacatttcc cttaccatca acgatctgcc catttttgat cgagtacccc gtgaatggaa
    11641 tatcatttgc taactgtata ccgattgaaa aagtactcat acctcctccg gcaggaagcc
    11701 ctccccatgt tgagggtgta aaagaataac ttttatccgc attgggtgta actgaatcga
    11761 tcgtatttcc agcggtagcc acccccatat agatactttt tgggaatgtg atagtagtac
    11821 catttactgt ggagccaata aacagattat ggatatctgg acggttatca ataaaagcga
    11881 ttgctttggt tacgccttgt aacgcagttt tatccgcact catcgatccg ttaaccgcaa
    11941 caatgactcc atctttggca tatatcactg tatatccatc tggtatggta tgtccgttga
    12001 aattcgcagt ggccgcaaca gtactaaatg tctggcttct acctgtttct gaataagctt
    12061 tctcccctgc tgcttttgct gctgtgattt ctttttctgt cggatcaatc agttgagtcg
    12121 aggatgtggt tgaggttgtc tcgttgttgc tagactgatt ggtgctttct atggactgta
    12181 tttcagaata gggtggacta tttgtctcct ctgtcgtttg gttagcaaaa tttgacgttt
    12241 ctgtataaac gtttacataa atacttgata agctccctaa gaaagtaaaa atcaagatga
    12301 tcgaaatcat aatgggatgt aagtattttc ttttagatac agctttgagt ctagaaacaa
    12361 aatgtttttg acatatacgt tggattttat tttgagtttt cttaatcatt ttcatccctc
    12421 ctctcaataa aaaatcatca aataatcctt tacacgttat tctaaattta atttttatta
    12481 ttttattgat gtatagaaag tttggggctt tttttctctt tttattctaa ggttatttta
    12541 gtcttgtcct ttaatacaaa gattttattt ttaaataaaa aatactcttt ttttacgatt
    12601 attgaaaaaa aaagataaaa cttgattaat tgaagtattg cttaaatttg gaagctatga
    12661 gggaagaata aaagagttag gacgggatta tctactattt ttctttgttt taaatatttg
    12721 ttatctttga acataaaaga gaaatgtgtc gactgcagtg ttgtgtccct catcacgaat
    12781 aaacggtgtt caattagctg atcttgtatt cacttaaaaa atggtaaagt acgagttgct
    12841 attccccatt ttcaattttc taacgctcag gacaaaatac tgttttcaca acctcattgg
    12901 aataaaagca tatatattgt ttcaagaacg aaatcttgtt atctttttaa agggcatctg
    12961 tccaaaatct aattttagga ggtacgtttt ggtatttatt cgtacaaata aaagagaatt
    13021 atctttattc atgtaacgca tccaattgat tttttcatgt acgctcctgg aacgatttta
    13081 ctgacgattg cttatttaac tgcgaatcgc tcattagctt ttatcatagc tatccatatt
    13141 ttgaataacg ttcttggctt tgtattatag atacagatga caaaaaaagt tcaagtatgc
    13201 ggtgtagaac caatatcgca tacttgaact tttttcaatg agtataaatt aaaacttcta
    13261 attttcaatt cccatcatct gatatgcccg accgtctgaa cttcttttga aaaagccaaa
    13321 tgtgattaga taacgtcttt gttcgacata atcgccacta gaaaatacgt tcagcagtat
    13381 cgaattaacc tctgtttctg tataagtcac tccatggtca aagcgtttca agacttcttt
    13441 caataggatg tatttctttt ttgttgaact tggtacttgt tttacttttc catcattcat
    13501 gaatgtgtct aaaactttca tcttttcttg ctccgtataa gtataaacca tcttctttct
    13561 ccttttgatt ctaagaatac tccatttatg ttagaatatt ctggattttt tattaaagcg
    13621 gttactctta agaaagatat tatcatagtg ctcttttttt tactactact tataggtaga
    13681 tttattctaa tccattattc tcccctacca ataattaaag aaaaaactgg atcagggtgt
    13741 tcaaattaca tgctaagaaa aaagaaccct tgaataccaa gggttctttc tcagtctgat
    13801 aacaatgatt aacgacggat ttctttgata cttgtgaaaa gtcgttaaag tattgatata
    13861 aaaggatttt tattacctct gactacatat tgactaattt gttaaaaaat cgtttttcaa
    13921 gaatcctgta ataccagtgc tttcaccgtt tttttaactc tctaaagaac taaaagcaat
    13981 cagaggtttt accttttcat ttgacgttaa gtggcgataa attttcgaag ttgtttggtc
    14041 agtatggcct aagcgatctt tcaagacttc ccagctacag tgttccgcta ctaagcttgc
    14101 cattgtatga cgagctaaat gagtatgaaa tggcttatta attcctgagc gattcacgca
    14161 ccgtttgacg tgatcattta catactctcg acgataagga acaccacgtt tactagaatc
    14221 aagatacaca aacaaatatg tttcttctat aataaacctg taatgttgcc tcatctcacc
    14281 caaagcctta atcaactgtt gtagcttttc cataactaga ggagttacta gaactcgtct
    14341 agcagaacta actgtcttag tagtttcaat tcgaaaatcc ttactcttac ctttaactgc
    14401 cgtttgctta tagaacagaa tttcatttct tttgaaatct atatctccag gctgtagagc
    14461 aagcgcctcg ctgactcggc agccagtgta aaatagaaca tggaaaagta cagacatcgg
    14521 taattcctca tgaacaatgc cataattcaa aaaagttctc aattcatcga cagtaagaaa
    14581 cttgtcctca atattattta tggcttcttt taaatcagtt accgttaact gatattttgg
    14641 cattctcaca gacttcattg gattttcact tatcaaattc tttctttgac aatatttaaa
    14701 aatcatattt agaacttgaa taagtgattg taaactattt ttggcatagc caacatttgt
    14761 tccattaacg ccacattcct ttaaggtaaa aagcaattct tgaaggcact ctggtgtcaa
    14821 atcagacaac tttttatcac caatccatcg aacaataatt tttaattgtt cctctcgctt
    14881 atcataggtt atttcctttt gttcatttaa cgaacggtaa tattggaacc attgctcacc
    14941 tacaacacta aacttgtcat tgcttgcaac aatttttttc ttaagccttt gttgtttctc
    15001 catttccaga taagcgagtt gcgcctcacg ttttgaatta aagccacgtc ttgttgttcg
    15061 atatgcttga aagtaccatg tgatcctacc agtagaactg atttgcttct tgaatcgatc
    15121 tgttttttcc atttattgat tcctcctatt ttgaaggaac ccaacaagca gaaacccttt
    15181 ggaaatcttt ctatctatgt catcattgta ccgcatctta gaaagaaaat gtaacttata
    15241 aagatcgaag tagtcgcaat ttttctcgat agtcattcga atcactcttt ctcatccatt
    15301 ctaaaacatc atcacgaaaa tagtgtcctc gaatcccgta ccaacaggga ggaaactcac
    15361 caagttttac taaacggttc agtgtactat cacttatctg aaatagtcgc tttaaatcag
    15421 tatttgttaa taccagaggt aaatgactga ctgcaagcaa tttttccgtg taatcttcca
    15481 gttttttttg taaaattgaa tagaactcta tttccagaga attaacattt gttttaactt
    15541 ccaactccat cacccttctc tctcaaaatc aaaacgacca ccacggtacc ccttaaaatt
    15601 gtaaaaaaac actccagtac tccatcaaaa cggactagaa aagaggaatt tttaatatga
    15661 aacaaggaat tgcagacata aaaataatta aagaaattct tgaaaaatct acggctaatg
    15721 caatagcatt cggaacagga atcaacttga gtacaataaa aaaacttaaa agtggagaga
    15781 gagctgaaga aaaattaaat cttgccgatg ctattaaaat cacagaattt ggcatgaaaa
    15841 atatgccaac caaaatcgaa atatggaaat agtagttttt ctgatctatc agctgttttg
    15901 ccaaagcaca taggaatctc acctcccccc agtaatggcg ggccgatttg gttacggaag
    15961 tatcattatc gtagtcgcga ttctcatatt aaaatttgtc gcttaaaagc taaccttgtc
    16021 atggcgtaac tagagaatca aaatctacat gtactgatag atttgctatt catttgtcaa
    16081 agagcgctag gctattttca gcctatggaa atcctttatt ttgacccgat aaaaaacttc
    16141 catagaatga aaaggaaagg gaaaaaatac tttaacgagt tgtatcaaat tcaagtatct
    16201 tctcaatcaa ttttgtttcc agttgtctac gcatatattc atctacatac ataaccattc
    16261 ctttttcttc ttcataaact ggtttcatgg ctaaccgtga aatataattt tgatattttg
    16321 acagaacgat ggacatggca attgaatcac cagaagctgc ggctttgatt gtcgttagtg
    16381 gtatgaatgg tatatatcgt ttattttgct tcatatttga cacccaaata ctttcctagc
    16441 tcttccaaag ccatttgtcg ttggtaccaa acactgccga gacttttccc aataatatcg
    16501 ccaatttcac gatcattaag accgatgagg aaggacataa aaatgatttc ttgtctttga
    16561 ctaggtaatg ctgcaatcgc atttgccaac tcctcattgg aaataaagat tttcatacca
    16621 aggacaataa aagtaccact actattcaaa tttggttcca aataatagaa ctctgtacct
    16681 aacccttttt gttccaatat ttccattgat atttgccgtt ggcgaaatct agcgtacttc
    16741 ttttgaatat ttaacgcctc attgcagact actttcttac aaaaactgtc aaacgtatgt
    16801 tgaatgtggg tttcctctga gtcgcccata atattctccc cctcaaaaaa ttcattcaac
    16861 tcgttttact tctatccctt tccattatta ctacaatcta gga
//
LOCUS       DACBZK010000058        16700 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.060, whole genome shotgun sequence.
ACCESSION   DACBZK010000058 DACBZK010000000
VERSION     DACBZK010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16700
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.060"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            176..403
                     /locus_tag="IVD66_002025"
     CDS             176..403
                     /locus_tag="IVD66_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HAP6146229.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            419..1585
                     /locus_tag="IVD66_002026"
     CDS             419..1585
                     /locus_tag="IVD66_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HAP6146230.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            1820..2863
                     /gene="hrcA"
                     /locus_tag="IVD66_002027"
     CDS             1820..2863
                     /gene="hrcA"
                     /locus_tag="IVD66_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HAP6146231.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            2957..3520
                     /gene="grpE"
                     /locus_tag="IVD66_002028"
     CDS             2957..3520
                     /gene="grpE"
                     /locus_tag="IVD66_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HAP6146232.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDRYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            3571..5400
                     /gene="dnaK"
                     /locus_tag="IVD66_002029"
     CDS             3571..5400
                     /gene="dnaK"
                     /locus_tag="IVD66_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HAP6146233.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGKRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            5551..6717
                     /gene="dnaJ"
                     /locus_tag="IVD66_002030"
     CDS             5551..6717
                     /gene="dnaJ"
                     /locus_tag="IVD66_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HAP6146234.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(7085..7822)
                     /locus_tag="IVD66_002031"
     CDS             complement(7085..7822)
                     /locus_tag="IVD66_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP6146235.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(7824..9326)
                     /locus_tag="IVD66_002032"
     CDS             complement(7824..9326)
                     /locus_tag="IVD66_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880041.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP6146236.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIEKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            9585..11579
                     /gene="uvrB"
                     /locus_tag="IVD66_002033"
     CDS             9585..11579
                     /gene="uvrB"
                     /locus_tag="IVD66_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HAP6146237.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            11589..14405
                     /gene="uvrA"
                     /locus_tag="IVD66_002034"
     CDS             11589..14405
                     /gene="uvrA"
                     /locus_tag="IVD66_002034"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAP6146238.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            14668..15933
                     /locus_tag="IVD66_002035"
     CDS             14668..15933
                     /locus_tag="IVD66_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HAP6146239.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYAGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            15937..16668
                     /locus_tag="IVD66_002036"
     CDS             15937..16668
                     /locus_tag="IVD66_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HAP6146240.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
BASE COUNT         5504 a         2901 c         3661 g         4634 t
ORIGIN      
        1 tttttatgaa taaaataagg acaaaattgt ttaggaagaa tcatgagtgt aaaaaaatca
       61 tccaagaagt cgattcttgg attttttagt ggatttgttc gccaaatacg tttagtatgc
      121 gtatatgaga ggttgtaagc aaagcgttgt ggtctgagca cttaaggagg aatctgtgaa
      181 aatagctttt catatttttg cagattttga cttaatgccg aaggtcagct ttgcgattac
      241 cgtttatcga gaggctgtaa aagcaccgtg tagctccgat gacaataagc aagcattttt
      301 agagctaggt ttccttgatt ctaaatatgc ggcttatttc aatgagttgg tgcttgaacg
      361 cgattttaag aaggtcgaaa acaggcacga cttttcgacg taaggagaaa gaatttcaat
      421 gatagaaaca ataaatcccg cagaaaacaa ggtttctgcg tacattcata tcccattttg
      481 cgagcatatc tgctattact gtgactttaa taaagttttt ttagaagggc agccagtaga
      541 tgagtatgtg gaaatgctgc tgaatgaaat gagattaatg ctggaaagtc atcctacagc
      601 gaatttggaa acactttatg taggaggcgg aacaccaact tctttatctg ctaaacaact
      661 tgatcgacta ttatcaggtg ctagagagat cctgcctttt caaaatggta atgagtttac
      721 tgtagaagcg aatcctggtg atttgacccg tgaaaaactt caagtgatga aaaactatgg
      781 cgtcaatcgt ttatccatgg gagtgcagac atttgacaat cgcttattga aaaaaattgg
      841 acgtaaacat actgcagaag atgtgtatca aacaatgcaa tttttagaag cagaaaattt
      901 taccaatgta agcatcgatt tgatttatgc attaccggga caaacactag aaggatatcg
      961 ggatactttg gaaaaagctt tggctttgga tctgcctcac tattctttgt actcattgat
     1021 cctcgaaaac aaaacaatgt tcatgaactg ggtacgacaa ggaagactcg aactgcctga
     1081 tcaggaaacg gaaaccagaa tgtttgaaga gacgattgaa gcaatggaaa agcatggacg
     1141 tcaccaatat gaaataagta actttgggct ctccggacat gaatctcaac ataacctcat
     1201 gtactggaac aatgaccact attttgggtt tggagctggt gctagcggtt atcttggaga
     1261 tattcgttac cgcaacaaag gaccgatcca acactattta cgcccattac gagcaaatga
     1321 acgcccggta ttggaagaag aaaaattgac acgaaaaaat caaatagaag aagaaatgtt
     1381 cttaggacta agaaaaaaaa cagggattac taaaaaacat ttctatgatc gctatcaaaa
     1441 aacaattgaa tcggtgtacg gtgatgtgct aagggaatta gagcaagaag ggttacttgt
     1501 taatgaagaa gaccgtgttt atttgacacc aagagggact tttttgggga acaatgtgtt
     1561 tgagcgcttt ttatttgaaa aatagtttga agaatatttg ttttttatcg aaacttgaaa
     1621 agaaaaagtt tagaaagttt gacaatgagg tattgaagta ttgatataac tggatttaca
     1681 tcaattattt agaattagca ctcttgtgtt tagagtgcta aaaaatggag tctttctctt
     1741 gacaggagaa gggcttcttg ctatatttat aagtgaatta gcacttagaa tatatgagtg
     1801 ctaatgagag gtgaggaaga tgttaacaaa gcgacaaaac gacattttac gtctgatcat
     1861 ccaacactat acgagtagtg gcgtgcccgt tggttccaaa acattaatgt ctgagggagt
     1921 caaggccagc tcagcaacga ttcgcaatga tatgaaagca ttagaagatg aaggattgct
     1981 gttgaagact cactcttctt ctgggcggat tccatctgct ttaggctatc gttattacgt
     2041 ggatcatttg ttaaaacctg ctcgcgtagc agaagatgat ttgctgctga ttcgtcagtc
     2101 tctaggcaga gaatttcatg aaatcaatga gattattaag caatctgctg agatattatc
     2161 tgagctgaca agctatacga ctttttcatt gggacctgaa ataaaagacc gccgactgac
     2221 tggctttcgt atcgtaccct tgaataatcg acagattatt gctatcgtcg taacagatat
     2281 ggggaatgta gaaagccaag tgttcactct tcccgaatat atgggaagtc aggaactaga
     2341 aaaaatggta cagattgtaa acgaccgtct agtcggagat cctctgatga cggtgtacca
     2401 taaacttcgt acggagattc cgatgattct tcataaatat ttccagacga cagaagggat
     2461 gtctcagtta tttgacaccg ttcttggtca tgtttttgaa gaaaaggttt atgtcagtgg
     2521 acaaatgaat ctcttggatt atgagccccg tcaagatctt gatcagttca aatcgatgtt
     2581 ttcttttatg aaagactcag acggacttac acaaatgatc actccgatgg atagcaatat
     2641 tcatatcaag attggtgctg aattaggcaa tgatttattg cagaatatga gtatgattca
     2701 agcaagttac gagatagatg gtcatggaag aggtacaata gccttgttag ggcctactag
     2761 tatgccttat tctcggatgt tcggtctagt cgatgtttat cgaagagaac tagcagctaa
     2821 acttgctgat tattaccgct cgcttgactt gtcaaactcg taatgtgaat aacgaagcta
     2881 tttgcagctg atcgttctct ctttcttagt aagagcaatc aaacagctga ctgaataatg
     2941 aaaggaagac tgtatcgtga aagaaaatca agaagaacta gataaagaaa tgacagatgc
     3001 tcagccagaa ccggaaatcg atgtcgaagc tgcagaagat tcgggtattt cagaagctga
     3061 agcggaagaa ttcgaaacag cgaaattaaa agctgagtta gaagaaatgg aagatagata
     3121 cttgcgggct cgtgctgaaa tcgcaaatat ggcaaatcga ggaaaaaatg agcgtgagca
     3181 attacaaaaa taccgttcac aagatttagc caaaaaatta cttccatcaa ttgacaacct
     3241 ggaacgtgca ttagccacag aagtgtcaga tgatcaaggg gcaggtttga aaaaaggcgt
     3301 ggaaatggtc ttggaaagtt tgcgtaacgc actggaagaa gaaggaattg aaaaaatccc
     3361 tgctaaagga gaagcctttg atcctaatct tcatcaagca gtacaaactg ttccagcgac
     3421 tgaagataca ccagccgata cgattgtaga agtactacaa gaaggctaca aattacatga
     3481 tcgcgtgtta agaccaacta tggtcattgt tgcacaataa ttgtgcggat ataaaactta
     3541 cactttcaat taaagaagga gacgttaatt atgagtaaaa ttatcggtat tgacttaggt
     3601 acgactaact ctgcagtagc agtattggaa ggaaacgaag caaaaatcat cgctaaccca
     3661 gaaggaaaac gtacaacacc ttctgttgta tcattcaaaa atggagaaat ccaagtaggg
     3721 gaagttgcaa aacgtcaagc tgtgacaaac ccaaatacga tttcatcaat caaacgccat
     3781 atcggtgaag caggttacaa agtagatgta gaaggtaaat catatacacc acaagaaatc
     3841 tcagcaatga tccttcaata tatcaaagga ttcgcagaag actatttagg tgaaaaagtc
     3901 gaaaaagcag ttatcactgt gccagcttac tttaatgatg cacaacgtca agcaacaaaa
     3961 gatgctggta agatcgctgg tctagaagta gaacgtatcg tcaatgaacc aactgcagct
     4021 gctcttgcct atggtttaga taaaacagat cgcgacgaaa aaatcttagt attcgacctt
     4081 ggtggcggta cttttgacgt atctatcctt gaactaggag acggtgtctt tgatgtattg
     4141 tcaacagctg gcgacaacca tctaggtggg gacgactttg ataacaaaat catcgactac
     4201 atggtagcag aattcaaaaa agaaaacagc attgacttgt ctcaagacaa aatggcttta
     4261 caacgcttga aagacgctgc tgaaaaagcg aaaaaagatt tatctggcgt atcaagcaca
     4321 caaatcagct tgccatttat cacagcagga gaatctggac cattgcattt ggaaatgaca
     4381 ttgacacgtg caaaatttga tgaattaaca gctgacttag tagaacgtac aaaagtacca
     4441 gtacgtcaag cgttaaaaga tgcaggtctg tcacaatcag aaatcgacga agttatttta
     4501 gtcggtggat ctactcgtat ccctgcagtt gtagaagcag tacgtaaaga aacaggaaaa
     4561 gaaccaaaca aatcagttaa ccctgatgaa gtagttgcta tgggtgctgc tatccaaggt
     4621 ggcgtgatca ctggtgatgt gaaagatgtt gttttacttg acgttacacc attgtcatta
     4681 ggtatcgaaa caatgggtgg agtgttcact aaattgattg accgcaatac aacgattcca
     4741 acaagtaaat cacaagtatt ctcaactgcg gcagataatc aaccagcagt agacatccat
     4801 gtattacaag gtgaacgccc aatggctgct gacaacaaaa ctctaggaag attccaattg
     4861 acagatattc cagcagctcc tcgtggtatt ccacaaatcg aagtaacatt cgatattgat
     4921 aaaaacggga ttgtaaatgt atctgcgaaa gatctaggta cacaaaaaga acaaaaaatc
     4981 acgatcaaat cttcttcagg tctaacagat gaagaaatcg aacgtatggt gaaagatgca
     5041 gaagcaaacg ctgaagcaga taaagctcgt aaagaggaag ttgacctacg taatgatgta
     5101 gacgcattgc tattctctgt ggacaaaaca ttgaaagaat tagaaggcaa agtggacgaa
     5161 gaagaagtga aaaaagcaga aacagctcgt gacgaattaa aagccgctgt tgaagcaaac
     5221 aacatcgagg aaatgaaaac taaacgcgat gcattgaacg aaatcgttca aaacttgact
     5281 gttaaactat acgaacaagc tgcacaacaa caagctcaag aaaatccaga agcagctcaa
     5341 ggcggagcag atgatgtcgt tgatgctgat tttgaagaag tcgatggcga cgataaataa
     5401 tcagttcact gaatttcgag agaaggccaa agttgctact ttggcttttt cttttgaaaa
     5461 atagtttgaa gtatcggttt ttgtttcaaa caaaatatga tatgataaca agcgacgtga
     5521 aaatgatgag aaccaatagg aggaaagcct atggcaacaa aacgtgatta ttatgaagtc
     5581 ttagggctct caaaaggagc atcagaagat gaaataaaga aagcttatcg taagctttcg
     5641 aaaaaatacc atcctgacat caataaagaa cctgatgcgg aagaaaaatt caaagaagta
     5701 tcagaagcat atgagatttt aagtgacccg caaaaacgcg ctgcatacga ccaatacggg
     5761 catgcaggca cagatccaaa ttacggtgct ggtggagctg gtggcggatt tggtggattc
     5821 ggcggcttct ctggtggcgg cttcggtggt tttgaagata tcttcgactc tttctttgga
     5881 ggaggcggtc gatcagtcga tccaaatgcg cctcgtcaag gtgctgattt gcaatatacg
     5941 gtcgacttgt cttttgaaga agcgattttt ggtgtagaaa aagaaatcaa gtataatcgg
     6001 gaagaaatct gtcatacttg tggtggaaac ggtgcaaaac caggcacaca accaactact
     6061 tgtcataaat gtcatggtgc aggtacgatc aatgtagaac gccaaacgcc acttggacga
     6121 gtgatgagcc gtcaaacttg tgatgtttgt catggcacag ggaaagaaat caaagaacct
     6181 tgtccaacct gtcatggctc aggacatgag aagaaagcac attcagttaa agtgaatgta
     6241 ccagctggtg tagaagaagg acaacaaatg cgtttagctg gtcaaggaga agctggagaa
     6301 aacggcggac catttggtga tttgtatgtg gtctttcgtg tagaagaaag tgatatcttt
     6361 gatcgtgaag gttctgaaat ttactatgaa ttgcctttaa gttttgtaca agcagctttg
     6421 ggggatgaag tccaagtacc aactgtccat ggagatgtga aattgaagat ccctgctgga
     6481 acacagacag gtacgaactt ccgtttacgt ggaaaaggcg ctccgaagtt acgtggtggt
     6541 gcaacaggcg accaacatgt caaagtaaaa ctgatcacac cgaaaaatct aaatgaacaa
     6601 caaagagaag cattacgtgc attcgctgaa gctggcggca tcaaagttga agaacagcaa
     6661 gaagacggtt tcttcgataa gtttaaagat gcttttggcg ggaaaaagcg gaagtagttt
     6721 ttctagtaaa aatataaagt agacttgccc aaattttcta tttctagtaa aaacgctaag
     6781 tcattaataa ttaaaaacca gacgaacaat catacgttcg cctggttttt ttgtagttgt
     6841 catgtttgta ccaacaaaaa agccagcttt agaataagat aatcatcata gtttctgaag
     6901 gtggtatcga ctatgtactt gatatcgtca atgaaccgat ggtactttct tatgcgatgg
     6961 aacaggtaga gcgattgctt gtttgtgcag gagaacaagc gatgcggctg gtacagttaa
     7021 gtgaaaaaac aagaaactaa aaatgcccgg tcgtcatgaa gcaaccgggc atttttggtt
     7081 tttattaaat attcaatact ttattcaaga aatcttttgt ccgttcattt tgcggatttt
     7141 caaagatttg ttgaggcgtt ccgtcttcta aaaagtttcc gtcgtcaatg aacatgacac
     7201 gattggccac ttctttagcg aagcccattt cgtgcgtaac gataaccatc gtcatacctt
     7261 gttctgctaa ctttttcatg acgttcaaga catcaccgac catttcgggg tcgagtgcag
     7321 atgtaggctc atcaaaaagc atgatgtcag ggttcatcgc tagagcacga gcaatagcca
     7381 cacgctgttt ttgtccacca gaaagcattt caggatacat atctttttta tcttctagac
     7441 caactgtctg cagtaatttg attgcttttt tctctgcttc ttctctagat tctttcttca
     7501 ggtccatcgg tgctaaaatg atgttttcca aaatagaaag atgagggaat aggttaaagt
     7561 gctggaatac cattccgata tgttgtctca ccaagttgat atctgtgctt ttatccatca
     7621 agtgggcgcc gtcaataata atttcaccgt cagaaggttc ttctaaacga ttcaagcaac
     7681 gcaaaaatgt actttttcct gaacctgaag ggccaatgat acagacgaca tctccttcgt
     7741 tgatggatac attgatgtcg tttaatactg tgttatcgcc gtattttttg actaaatgct
     7801 caactaagat tttttctgcc atcttacttc accttctttt ctaaaacttt tgctaatttt
     7861 gtcaatgctg tgatcaaaat caagtacatg atcgcaatga tcaagtaaac atacgtactt
     7921 tgtgttgtac gtgcaacaat gatcttacca gtttgcagca attcgactac accgattgcg
     7981 gaaatgatcg ttgtgtcttt taatgagata acgaactgat tgacgaatga tgggatcatg
     8041 atgcgtattg cttgtggcaa aatgattttt tgcattgtcc gattataaga aagacctaaa
     8101 cttctggaag cttccatttg tccgacagga acggcgttga tcccgcctcg aacaatctct
     8161 gcgatataag cacttgcgtt aagagtcaag gtgataacac cagcaaggaa gtcaggaatc
     8221 gtaaatccaa cgataccagg caacccaaag aaaataaaga acgcaagaac catcattgga
     8281 attcctcgga tgatatcgac ataaatacta gcaattgtgc gaagagcgcg tattggtgct
     8341 acactgaata atccaaaaat cacaccgatt actatagcca aagcaaagga gatcaaagtt
     8401 aggagaattg ttctccaaag tcctttcaac aatgcttgat agttgttttg gataagtcca
     8461 agaaatgttg attcatcagc agtggaagac tcactagaag tttctgaacc atccgctaca
     8521 tattctttga taatcttatc gtattcgcct gttcttttta attctttcaa tccttcattg
     8581 aacatattaa gaagctcagg attttgtcct tttttaacgg caaatgcata ttttccgcca
     8641 gattcttttt cgatcggtgt ttccaattct tgtccttgtt tgatcgcata accgattacc
     8701 ggataatcat ccatcattgc atcgattgcg ccaactttta acccgtcgta caattgatca
     8761 gcagcatcaa aatatttgat agaatagcca tattcagatt catggtcgct taaaaattca
     8821 gcactttcgg taccaacttt tgctccgact gtttttcctt tcaaatcttc ataagacttg
     8881 atcgaagtat ctcctttttt gacagctaat tggatcccgc tatcaaagta agaatcagaa
     8941 aaatcatagc ttttctttcg ttcatctgtt acagtcattc cggcaatcat tccgtctgct
     9001 tgtcctgatt ccaaagcttg caaagcagca gagaaaccac ggtagtccat tcggatgtta
     9061 aatccttgca gtttggcgat gttttccatc aattttacat cgatgccttc gtactcgccc
     9121 tttgcgtttt gaaattcaaa tggagcaaaa gcagagtcac tggcaattac gtatacgtct
     9181 tttttgggct ctattttttg cattgtctcg cttgtgcttg actctgccgt tgtagtgttg
     9241 tcagcttgtg caacatgacc aaacgcaagt gtcacaagtc ctgtcattaa gaaaacaaat
     9301 gagtgaaata aatgctttct tttcataatc aacctcctaa atttccaata ttttattatt
     9361 ataggcgaaa agtgctgaat cagacaagac tgtaagctcg aaaaaatgaa aaaaatgcga
     9421 gtttctaaca ttttatgtta taaaacgtaa catgtataat aagataaaaa agtggcgaaa
     9481 gtatgttcgg tgtggtataa ttttttagta aggaatgcct ttgctttcct tttcttttta
     9541 ttggtcgtaa aatgaaaagg aatgaatgaa aaggaggacg aagaatgatt gagagagata
     9601 cctcccgaca ctttgagctt gtctcgaaat accaaccggc tggtgatcag cctgaagcga
     9661 ttaaccaatt agtggatggc gtagtcggcg ggaaaaaagc acaaatctta ttaggtgcga
     9721 ctggaacagg gaaaacatat acgatttcca atcttattga gaaagtgaat aaaccaacac
     9781 tgattattgc tcataataaa acattggctg gtcagctgta cggggaattc aaggaatttt
     9841 tccctaacaa tgctgttgaa tattttgttt cttattatga ttattatcag cctgaagctt
     9901 atgtgccttc aagcgatacg tatatcgaaa aagattcaag tgtaaatgat gagatcgaca
     9961 aattacgaca ttcggctact agttcattat tagaaagaaa tgatgtgatc gtcattgcat
    10021 ccgtttcatg tatttttgga ttaggttcgc cttttgagta ccaaaaacaa gtagtttcga
    10081 ttcgacaggg agcagaacta gatcgcaatc agttgattcg tgacttagtc agtatccaat
    10141 tcgaaagaaa tgatatagat tttcagcgcg gtcgttttcg agtgcgcggt gatgtcgtgg
    10201 agatttttcc ggcttcaaga gatgaacgtg ccttacgtgt ggagtttttt ggagatgagg
    10261 tcgaacgtat ccgagaagtc aatgcactga caggtgaagt tttaggagaa acggaacacg
    10321 tggcaatctt cccggcgact cactttgtga cgaatgatga acatatggag catgccgtag
    10381 cgaatatcaa agcggaatta gaacagcgtt taactgtctt gcgaaatgaa aacaaacttc
    10441 tggaagctca acgtttagaa cagcgaacca attacgatat tgaaatgatg ttagaaatgg
    10501 gctacacgtc gggaattgaa aattattctc ggcatatgga cggacgtaaa gaaggtgaac
    10561 cgccttatac gctattggat ttctttcctg aagatttttt gatcgtggcg gacgaatcgc
    10621 acgtaaccat gcctcaaatc agaggaatgt ataatggtga ccgagcgaga aaacagatgc
    10681 tagtagatta cggtttccgt ttgccatctg ctttagacaa tcggccactt cggttagaag
    10741 agtttgaaaa acatgtcaat cagatcattt atgtctctgc gacgccagga ccatatgaac
    10801 atgaacaaac agataccgtt atccaacaaa tcatccgtcc gacagggctg cttgacccag
    10861 tgatcgaagt tcgtccaatc atgggacaaa tcgatgatct agtaggcgaa ataaatgaac
    10921 gagtcgaaaa agaccagcgg gtgtttgtaa cgacattgac gaaaaaaatg gcagaagacc
    10981 tcacagatta tttcaaagaa ttagggatca aagtcaaata tttgcatagt gatatcaaaa
    11041 cgctggaacg aacagaaatc attcgagatc ttcgattagg tgaatttgat gtgttagttg
    11101 gaatcaattt gcttcgtgaa ggattagacg tacctgaagt ttcccttgtt gctatcttgg
    11161 atgcggataa agaaggcttt ttacgtagtg aacgttcctt agtccaaacg attggacgag
    11221 ctgctcggaa tgaagaaggt aaagtaatca tgtacgcaga caaagtaaca gattctatgc
    11281 gtctagcgat ggatgaaacg tcaagacgtc gtacgattca gcagaagtac aatgaagaac
    11341 atgggatcgt tccaaaaacg atcattaaag aaatccgaga tttgatttct attacgaaag
    11401 aatcggaaga tgatacaaaa gaagcggtac aagtctcgta cgaagaaatg acgaaggaag
    11461 aaaaagacac gttattgatg aaattagaaa aagaaatgaa agatgcggca aaagctttgg
    11521 attttgaaac agccgcgaat gtgcgagata tgattttaga attaaaagct tcaaagtagg
    11581 aggacaacat ggctaacgat aaaattacga ttcatggtgc acgtgcccat aacttgaaaa
    11641 atatagatgt aacgattcca cgagataaat tcgtggtcgt tacaggtttg tccggttctg
    11701 gaaaaagttc cctagcattt gatacgctgt acgctgaagg gcagcggaga tacgtagaga
    11761 gcctttctgc ttatgctcgt cagtttttag gacaaatgga taagccggac gtagatagca
    11821 tcgacggatt gagtccggcg atttctattg atcagaaaac aacaagtaaa aatcctcggt
    11881 cgacagtagg tactgtgacg gaaatcaatg actatttacg cttgttgttt gcacgtgtag
    11941 gacatccgat ttgtcccaac gatcatatcg agattaccag tcaatcagta gatcaaatgg
    12001 cagatcaagt aatggctttg cctgagcgca caaagatcca agtgttggca ccgatcgtgg
    12061 taaagaaaaa aggacaacat aaaaaaatat tcgaacgaat ccaaaaagag ggatacgtcc
    12121 gcgttcgagt cgatggtgag atctatgatt taagtgaagt gcctgagctg gagaaaaaca
    12181 aaaaacatga tatcgcgatc gtcatcgacc ggatcattgt gaaagaaggg attcgttctc
    12241 gcctatttga ttctttagag gcggccctgc gattagcaga cggctatgct ctggttgacg
    12301 tgatcggtga agaagaaatg ttgtttagcg aacactatgc ctgtccttat tgcggattta
    12361 ctgttggcga actagaacca agactgttct cattcaatgc gccttttgga gcttgtccag
    12421 actgtgatgg tttaggtgtc aaattagaag tcgatcaaga tttagtgatt ccagatagaa
    12481 cgaagacact tagtcaaggt gctatcgttc catggaatcc aatcagctct cagtattatc
    12541 ctcaaatgtt agcgcaggct tgtgaaagtt tcggtatcga tttagataca ccattcgaag
    12601 aattaccgga agagcatcag gagatcatct tgaatgggac agatgatctt ttccatttcc
    12661 attatgaaaa tgattttggt ggcgttcgcg atgtagaaac gactttcgaa ggggtattga
    12721 agaatatcga gcgtcgttat catgatacga acagtgattt cacgcgtgag caaatgcgtc
    12781 tttatatgac agaattaact tgtcagacat gtaaaggtta tcgattgaat ccccaagctc
    12841 tatctgttca aatcaatgga acgaatatcg ggcaaacaaa tgagttgtct attcaaaaag
    12901 cagtagattt cttctcaaac ttaacgttat ctgaacaaga gaaagtaatt gccaaaccga
    12961 ttttaaaaga agtaaatgac agactttcat tcttggaaaa tgtgggacta gactatctaa
    13021 ctttgagtcg cgcttccgga acattatctg ggggagaagc gcagcgaatc agattggcta
    13081 cacaaattgg atcgaatctt tctggagttt tgtatatttt agatgaacca tcgatcggat
    13141 tgcatcaacg cgacaacgat cgactgattg gctcattaaa gaaaatgcgt gatcttggca
    13201 acaccctcgt tgtagtcgaa catgatgaag atacgatgtg ggcagcagat tatttgattg
    13261 acgtcggacc tggggccgga gaacaaggcg gacaaatcgt ggctgcaggc actcctgaag
    13321 aagtagctaa tgatgaaaat tctttgacag ggaaatatct ttcagggaaa aaatcaatcc
    13381 ctgtaccaaa agaacgccgt aaaggtaatg ggaaagcaat caagatcact ggtgcttcag
    13441 aaaacaatct gaaaaatatt agtgttgaat ttccattagg agaatttgta gcagtcacag
    13501 gtgtgtctgg ttctggaaag agtacattgg tcaatagtat cttaaagaaa tcgttagcgc
    13561 aaaaattaaa taagaattct gctaagccag gtaaattcaa gacaatttcc ggctacgaaa
    13621 gtatcgaaaa gatcatcgat atcgatcaaa gcccaatcgg ccggacgccg agaagtaatc
    13681 cagcgactta tacaagtgta tttgatgata tccgtgggtt atttgctcaa acgaacgagg
    13741 caaaaatgcg gggttataag aaagggcgtt ttagtttcaa cgtaaaaggc ggtcgttgtg
    13801 aagcttgtcg cggggatgga attattaaga tcgaaatgca ctttttgcct gatgtctatg
    13861 ttccttgtga agtatgtcat ggtaaacgat ataattctga aacattagaa gtgcattaca
    13921 aaggaaaaag cattgctgat attttggaaa tgacagtaga ggatgctgta gaattcttca
    13981 agcacattcc aaagattcat cgcaaactgc aaacgattgt tgatgttggc ttaggttatg
    14041 tgacgatggg gcaaccagca acgacattgt ccggtggtga ggcacaacgg atgaaacttg
    14101 ccagtgaatt gcacaaaatc tctaatggaa agaatttcta tatactagat gaaccaacga
    14161 caggacttca tagcgatgac atcgcccgct tgttgcatgt attacaaaga ttagtagatg
    14221 ctggtaacac agttttagtg attgaacaca atctagatgt aatcaaaaca gcagattata
    14281 tcattgattt aggaccagaa ggtggagaag gtggaggaac gatccttgcg actggaacac
    14341 cagaagaaat cattaacgta aaagaaagtt atacaggtca ctatttgaaa aaaataatgg
    14401 tataaagagg atagatagct gagatagtta aaaaaacata aaaaaatgaa tttttgcttg
    14461 ttttattaat atcagtgttc tagaatcatt acatggtagt tctttctaca ctgattggta
    14521 tagataaaaa cttcctataa gttcaatccg ttcaaaaaag aattgagcaa tcggaggact
    14581 ttcctttgat tgcttttttc tttatggtat gatattcctt gtgtagttgg aaaagaaaaa
    14641 caagagatta tgagtaagtg agagataatg atgaacagta ttgaaaatga agaatttatc
    14701 cctatattat taggaagcga catgaacgtt tatggtatgg cacgttcttt taatgaagca
    14761 tacggcaaaa tctgccaagc atatgcttcg gatcagttag cccctacccg ctacagtaaa
    14821 attgtcaatg tagaagttat tccaggattt gataaagacc ctgtatttat cgagacgatg
    14881 cttcgtttgg caaaagaaag atattctgat aagagtaaaa aatatctttt gattgcttgt
    14941 ggtgatggat atgcagaatt gatctcccaa cataaacaag agctgtcaga atattttatc
    15001 tgtccatata ttgattattc tttatttgaa aggctgatca ataaagtaag cttttatgaa
    15061 gtttgtgaag aatatgatct tccgtatcct aaaacattga tcgtcagaga agaaatgtta
    15121 gtaaatggac atttggaaca ggaattgcct tttgaattcc cagttgcttt gaaacctgca
    15181 aacagtgtgg agtatctttc tgtccaattt gaaggaagaa aaaaagcttt tattttagag
    15241 actagagaag agttcgattt aattttaggc cggatatacg aagccggtta taaaagtgaa
    15301 atgattgtac aagattttat cccgggtgat gatagtaata tgcgtgtgct aaatgcgtat
    15361 gtagatgaag atcatcaagt tcggatgatg tgccttggtc atccactatt agaagatcct
    15421 acaccagcat cgattggtaa ttacgttgtg atcatgccag attataacga aaaaatctat
    15481 caaaccatta aggcattttt ggaaaaaatc gaatatgcag gctttgccaa tttcgatatg
    15541 aagtatgatc ctagagatgg agaatataaa ttatttgaaa tcaatttgag acaaggtcgt
    15601 agcagtttct ttgtgacatt gaacggcttg aatctggctc gttttgtcac agaagatcga
    15661 gtgttcaaca aaccctttgt tgaaacgacc tatggaacga atcaatcaga taaagcaaga
    15721 ttatggatgg gtgtgcccaa aaaaatcttt ttagaatatg ctcgggaaaa tgaagacaaa
    15781 aaactagctg agcaaatgat caaagaaaat cgttacggta ctactgtatt ttatgaaaaa
    15841 gaccgatcaa tcaagcgctg gttgttgatg aaatatatgt tccataacta tattccaaga
    15901 ttcaaaaagt attttcatgt gaaagaaggc tagttcatgg agaatttttt cagtatttta
    15961 ggcggaatgg gcacgatggc gacagaaagt tttgttcgct tgatcaacca ccgaacgaaa
    16021 gctacaaaag atcaagaata tttgaattat gtcttattca atcatgcaac agttcctgat
    16081 cgtacagctt atattttaga tcgatcagaa gaaaatccaa tgccgtttct gctggatgat
    16141 attgagaaac aaaatttatt gcgaccaaac ttcattgtgt tgacttgtaa caccgcacac
    16201 tacttttttg aagagttaca agcggcaacg gatattccta tcttgcatat gccaagagaa
    16261 gcagcaaatg aacttgtccg tcagcatacg acagggagag tagcgattct aggaacagaa
    16321 ggaagtatga aagctggaat ctatgaacgc gaagtcaaaa atcttggttt cgaaacagtg
    16381 attcctgata ctgcgcttca agaaaaaatc aattacctga tctatcatga gatcaaggaa
    16441 tcggattatt tgaatcaaga gctctattac gaaatcttag aggaagcggt agagcgccta
    16501 aactgtgaaa aagtcatcct aggttgcaca gaattatctt tgatgcatga atttgctgaa
    16561 gataatcatt acccagtgat cgatgctcaa tctattttag cggatcgaac gatcgaacgt
    16621 gcattagctg aaagaagcga ggcattggat acagcatcgg aaaagtaaaa aaattggatt
    16681 tggggcaaat atcctaaaag
//
LOCUS       DACBZK010000059        16669 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.061, whole genome shotgun sequence.
ACCESSION   DACBZK010000059 DACBZK010000000
VERSION     DACBZK010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16669
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.061"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..1350
                     /locus_tag="IVD66_002037"
     CDS             <1..1350
                     /locus_tag="IVD66_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP6146241.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1484..2827
                     /locus_tag="IVD66_002038"
     CDS             1484..2827
                     /locus_tag="IVD66_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP6146242.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            2939..4390
                     /locus_tag="IVD66_002039"
     CDS             2939..4390
                     /locus_tag="IVD66_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAP6146243.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            4739..5371
                     /locus_tag="IVD66_002040"
     CDS             4739..5371
                     /locus_tag="IVD66_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HAP6146244.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            5959..7398
                     /locus_tag="IVD66_002041"
     CDS             5959..7398
                     /locus_tag="IVD66_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6146245.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            7693..7911
                     /locus_tag="IVD66_002042"
                     /pseudo
     CDS             7693..7911
                     /locus_tag="IVD66_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174271.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8160..8375
                     /locus_tag="IVD66_002043"
     CDS             8160..8375
                     /locus_tag="IVD66_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146246.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(8592..8848)
                     /locus_tag="IVD66_002044"
                     /pseudo
     CDS             complement(8592..8848)
                     /locus_tag="IVD66_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(9035..9946)
                     /locus_tag="IVD66_002045"
     CDS             complement(9035..9946)
                     /locus_tag="IVD66_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP6146247.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(9965..10969)
                     /locus_tag="IVD66_002046"
     CDS             complement(9965..10969)
                     /locus_tag="IVD66_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAP6146248.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(10966..13089)
                     /locus_tag="IVD66_002047"
     CDS             complement(10966..13089)
                     /locus_tag="IVD66_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP6146249.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(13094..15541)
                     /locus_tag="IVD66_002048"
     CDS             complement(13094..15541)
                     /locus_tag="IVD66_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP6146250.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(15528..15917)
                     /locus_tag="IVD66_002049"
     CDS             complement(15528..15917)
                     /locus_tag="IVD66_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP6146251.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(15977..16480)
                     /locus_tag="IVD66_002050"
     CDS             complement(15977..16480)
                     /locus_tag="IVD66_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAP6146252.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(16493..>16669)
                     /locus_tag="IVD66_002051"
     CDS             complement(16493..>16669)
                     /locus_tag="IVD66_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146253.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLSLFNRIVGA"
BASE COUNT         5385 a         3109 c         3069 g         5106 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1501 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1561 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1621 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1681 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1741 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1801 agttatatta gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc
     1861 taatattttt tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga
     1921 tagtactatt aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga
     1981 agccataaga aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc
     2041 gacttattac gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat
     2101 acatctttgt ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat
     2161 agtcactaca agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct
     2221 atctaatagt ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac
     2281 taatgaatac cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac
     2341 tttttttacg tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac
     2401 agcttatatt gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt
     2461 tacaaatggc ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac
     2521 agcacgatta ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc
     2581 ttttttgaga aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag
     2641 aatagtaggt gtacaacttt gtagtcaaga agatttatct ggactattat caatgttttc
     2701 tcttgctata gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca
     2761 tcctagtttt agccaaccct ataattttat tttaaaggca gtaacaggat taaacattga
     2821 aacataatcg ttactaaatg aaatcaagaa atatactgta ttactcaatt cattgaaaat
     2881 atttatcata atttttaata gaaaacacta ttaaagagaa aaaagagagg taaatcaaat
     2941 gaaaaaatct ttaaaacttg catcagcagt tatattaatg tcccaactcc ttatagcaac
     3001 acctttccat gtgttggcaa gcgaaaattc aacatacaaa attgcaaaag aaagaaccga
     3061 gacgactgaa atgagtaatt ccgatgtaac agcagagagt agtgaacttt tgacaacttc
     3121 atcaagtgaa agtagtacga cttcaaatgc cgagtcttca acaacttcat caagtgaaag
     3181 tagtacgact tcaaatgccg agtcttcaac aacttcatca agtgaaagta gtacgacttc
     3241 aaatgccgag tcttcaacaa cttcgtcaag tgaaagtagt acgatttcaa gtaccgaatc
     3301 ttcaacaact tcaagtagta caagtgaaat aacttcttcg aaagtgacaa aaccaaacca
     3361 tatagaatct tcaaaaaagg aagcgccaaa aacggaagga caaacaaaaa ctttttcgac
     3421 accacagcaa atagaatcaa cagaatcttt ccaatcacaa ccaatactat ctggtaatga
     3481 agaaattcat tttgacaaaa atgaatctgt agaaaatttt attatgaaaa ttggtgagtc
     3541 tgcgagaaaa attggtcaga aatatgattt atatgcttct gttatgattg cacaagcgat
     3601 cttagaatct gccagtggtc aaagccagtt agctcaggca ccgaattaca atttatttgg
     3661 gataaaagga acttataatg gaaactttgt cattatggta acaaacgaag atttgggtaa
     3721 tggaacgctt tatacgaccc aatcaaaatt tagagtgtat gaaaactatg aggaaagctt
     3781 tgaagattat gccaaattat taactaaggg aattagtgga aataaagatt tttatgcagg
     3841 agcattaaaa gctaatagta aaacatatcg agaagcaact aaattcctta caggacggta
     3901 tgcaacagat acacaatact atttgaagct aaatgaatta attaaaacct acgatttaac
     3961 caactatgat aaagaagtta aaggtccaca aatgagtaag actggatacc aagtgcctat
     4021 tcataattat tcaataacca gtttgtttgg aaatcgtgga aatgaatttc accgaggact
     4081 tgatatggca gctacacagg gtgagccgat tcatgcagtt aaagctggta aggttgttaa
     4141 agcagagttt cactactctt ggggaaatta cgtggtgata caacacgaag atggatcaac
     4201 cgcgttatat gctcaccagc aacaatacct agtaaaaact ggagataatg ttttgcaagg
     4261 acaaataatt ggctatgtag gaagtactgg gaatagtact ggcccacacc ttcatttgga
     4321 aatttgcaaa gatagtagtc tttctcagag catgttagtt gatccgaaaa ccttattatt
     4381 cggagactaa aaaaggtaat caatctgaca aagtaacaag aaaatggttg gattcttaga
     4441 cctttgatca ggatattgag actggaattg atatctcgat tacgatgggt ttgacaaata
     4501 aaacaagtcc attatcgaat atcgagtgta ttattgccgt ctttatgctc atattttgag
     4561 caggtttcac tagatgaaaa caatttatct atcttgagga tttcgtgtac gtatcgttca
     4621 gtcttgtatt gtaaattagt cataaaatca gactaagaaa aattggaaat atttttttct
     4681 gatttattaa aagttaattg aaattatatg gtacttcttt cttgggaggg taggtgcagt
     4741 gaaggaaaga tatggtcacc ttactgttgt tgaggagatt actcataatg gatataaaaa
     4801 atatcgttgc ctatgtgact gtgggaatga aacgattgta tatcgatcaa acttactatc
     4861 aggtagaacc aaaagttgtg gatgtggaaa ttataaaaat aggcataaat ataaaaattt
     4921 gacaaataaa acttttggta agttagttgc aatcaagcca actaaactgc gaagtgaagg
     4981 aactgttgtt tgggaatgtc aatgtctgtg tgggagaaaa aagttagtat cggcaaagcg
     5041 acttctaaaa ggtgatgtaa aaagctgtgg atgtttgaaa tcaaaaaagc atcacattga
     5101 aaataaaaaa ttcggattac ttactgcaaa gtatcctttg gacaataact gttcatggaa
     5161 aacaaaatgg gtttgtcatt gtgagtgtgg cagtatgtgt gagataagtt atagtaactt
     5221 attttttgga catactcaaa gttgtggatg tttaaaaagg caagaaacaa ggacatgtgt
     5281 tgaagggaca gtaatagagt gtctaacgtc aaaattaccg aaaaataata caagtggtgt
     5341 taagggagtt tatcgttcta aagagaaata gattgcgtat ataactttaa aaaaaaagag
     5401 gtactattta ggatcgtatg attctattaa gagtgcagct caagctagaa aagatgctga
     5461 aaataaattg tttcaacctt tgattgacaa atatcgaggt aatcattaat tattgtggat
     5521 aataattaac agtgatatat aaacatctat aatatattat tcatactatt gatatttagt
     5581 ataatcctat ggaattgaat atcatagcaa tgtatttgaa aagcaaattg gaaaacaaat
     5641 aggtgcaaca ccataaatat gaaaaaattg ggaaaaagta gaatggaaat ttgcttacgt
     5701 ctcacgagat agctcacact attaatctga agaacaatga agtcgacttt tagaaattgc
     5761 tagaagaaag taaagcgaat tatcactagt tactatagag taagttcaaa taaagcatct
     5821 ccaacttaca tggttacatg aggatatcaa atcgaaatta ctcaagcttc ctatggctag
     5881 agtcgcgaga agttgttggg cagtagacat aggttatatt gttcttagct acacgatcat
     5941 tagaaaggaa atcctattat gtatagttat caagaagatg caaaagtcca aaaaaatcgc
     6001 tggtggattt tgattgctat atctatgttt accttcatgt ccacattgga tggcagtatt
     6061 gtcaatattg cactacctac catctcagat gatatgggca taccaatgaa tcaagcggaa
     6121 tgggtagtgt ccgtttatct gatgattgtc tgttcttgtt tgttgctgtt tggtaaaatt
     6181 ggcgatagcc gtgggaaaat caaagtattt cggattggta cgctgatctt tgtcttggga
     6241 tcgctgttgt gtgggttcaa tcattcgcta ggtattttat tgttcgcacg ggtggtacaa
     6301 gccattggtg ctagtatgac tatggctaca aatgccggaa tcatcacgga agtctttccc
     6361 atacatgaac gtggtcgggc attgggagca ataggtgcgt ttgtttcatt aggctcgatt
     6421 gctggaccag gtcttggcgg cttgattttg tcccaatttt cttgggcgta cattttttgg
     6481 atcaatgtac cggtgggaat cgtaacgatg ttgattgctg aaaaattctt accaaaagat
     6541 atcaccatga gcggccatac aatcgatgga gggggctttg ctgccattgc ggctacgatt
     6601 atcagctttt ttggagcaat ctttttgggg caagaaagtg gctttttcca tccagtcccc
     6661 cttgtactgt tcgtaatttc agtgattgcc tttgtcagct ttttaaaagt tgaaaagaaa
     6721 gcagcctctc cattgatttc tttcggtatt tttaagaaca agatttttac catgagcttg
     6781 attacagcct tgttgatttt ttcttccaac ttctttgtca atgtagtgat tcctttttat
     6841 ctgcaaaatg ctcgcgggtt gagtcctagc tatgctgggc tgttgatgat ggtctttcct
     6901 ttgatgatgg tcgtcggggc gcctttaagc ggctacctga ccgaccgggt tggcccggag
     6961 attttggtat tagtaggctt gggcttattg tcggtaaccc aggtcatgta tatgtttttg
     7021 tcagtggact ctcctttgtg gctatacatt gtcgctactg ccatcatggg tgccggcaat
     7081 gccttgttcc agtcccccaa taatacgatg gttatgagct cggtcactat cgaaaacttg
     7141 ggactggcag gctcgatgaa ttcctttgcc cgaaatttgg ggatggtcag cgggatttcg
     7201 ctttctacga cggtcttata tcaagcgatg tctgctaaga tgggccagca agtaactaac
     7261 tatatcgcaa atcggccgga tgtcttttta tatggaatga agattacctt tttaggcagc
     7321 tttgttttgt gttttgttgc ctttttcctg actatctggc gtatcaaaaa acaaggaggt
     7381 attcagaaaa atgtctgaaa aaaccactgt tgaagaattt ttggaggcct gcgtatgggt
     7441 gagtgggatt tccatggatg atggaagatg aagtgaactt ctaaaagccg aaaaactcaa
     7501 gtattatctt caaaatacta gtgctcaatg agatgcttga tttgatcaca agaagactgc
     7561 gaaagccgct ggcaaccgca agctaggtat cccaccgatg gactacgttt tagaggctac
     7621 tggttatgaa tacggagcca acgctctcat ctgcataaga atacatcacc cagattatgt
     7681 aaagattttc gatacttctg tcaaaaaatc attaagatag ataaatgatt tccgtctagt
     7741 caaattggtt cagaatgtag acacacagat ggtaagaagt cactcacaat tcgagaatgg
     7801 acttgtccta tttgccgtat acatcataat cgaaacgtca acgatagtat caatattttg
     7861 accaagggct atgaatacaa gcattgcctt agaaaacatc aagaacctta ggaacaacgg
     7921 ggatagcttg gttaataaga gataccgctg tttaggcttg caagtatact cttttatcaa
     7981 gaattccgtg gctttagtca tgagaggctt aatactatga aaattttctt tagcattttt
     8041 gatttaggtt ccttttctaa ttataataag atgaccacta cagtaaccta ctgaaatata
     8101 taaacagcca ctgtagtacc attttcaaag tagtctatga gaggagaatc ttcattctta
     8161 tgaacgctgg aattgcggat atgaatttaa taaaaaaaac ccttaatgat tttacttcca
     8221 attcaatatc aaaaggtact ggtatcaatt taagcacaat aaaaaagctg aaaagtggtg
     8281 aaagatcagt ggaaaagctg aatcttttag atgctataaa aataacggaa tttgctatga
     8341 aaaatggaaa agctgagatt gaaatatgga gataattatc gtctagtgaa ttacttgcca
     8401 cttagctgaa tttaacgatc cttggtgctt gaagggggag attcttggga atagagcata
     8461 cttgcaagcc tatgtcttta ctaacaacga tatctcttat taaccaagct atccccgtag
     8521 ttctaaggct tttactttta tctaagcaat aatcgtattc aaaggaaatt tttgaccctt
     8581 agaaagtctc attttatcag acgtgagctt aggcattgct gaattttgtt aattcggttt
     8641 taggttgtgc tttgagcata atatgaaagt attctttatc acgatttcat tcatctaagg
     8701 taatgtgatg tgattctgaa attctttcaa aggcagtttt tgcataagct gacattacat
     8761 catcaatgac atgtttacaa tgtttcacta ctaaaataag ggggtaacca agaagaaaaa
     8821 ctgaatgatt atttgtatct aattccatgg tatatcaacc atttcctata tagactgatt
     8881 atgacatgga ttaaaataaa aaggcactat gtcttaattg tcggttttcg agttaccgaa
     8941 tggcattcat cacccaccta tagaggatgg gcgacttctg cctgaaataa gttacactac
     9001 ttataacttc taataaaatt agattgagtc attattattt aacatcaacg attttccagt
     9061 ttccattttt ttgtaatact aatttgtact gaaagtagct agtggttttt gatacattat
     9121 caaggtattt tatctttgta ctcactagaa aattttttcc gttttgtaga taaactggat
     9181 tctctaactc cgaaaacttt aagtcaatat tgattggtcg catcgcacca ttttcaacat
     9241 aatactccaa ttctttttca gaagctgatg gataaagttt aaaaaatgtt tctaaaaaat
     9301 cggtgatttc ttccgttgtt ttggcatcaa tttctgaatc gttttctact tgttttgctt
     9361 catattttgc cttgtctggc tttccaatca ttgttggcaa actagttact aaatgattcc
     9421 tgttttcatc ttcaaagatt gtcactcgat atgcagaaga aattgattgc gtcttttttc
     9481 cctctgtaat atgttgctcc actaaaaatg aaacgacaaa ttcttccgag tgtttttcaa
     9541 catctagaat ttttacagat tgaacttcgg aactcgtggg aatatctgct cgaaccatat
     9601 cttggattaa agcgagaccg ttttctgtaa ggtactgttc gagattactc attctctttt
     9661 caattgcttc tttgttattt ttccatgaaa aatattcttt cgcaaaatcc tctgtaaaac
     9721 tttcaacgcc agaagtattc actaccttct cttttataac cactttttca tgagttgtat
     9781 gttgatcaat ggcggtgaaa tttttataaa cgccaaaagc aagactacaa gacaataaaa
     9841 gccaaagggc aagcaccatt tttcgatgct tacccacgga tacaactcgt tcttttttct
     9901 tttttgggct cttttccttt tgattccgtt caatttttat cttcattctt tttcctcttt
     9961 tctcttattt gtatcggcca gctccgataa gatgctgccg ccaatagttt tccgttagat
    10021 tcgtccaccc cactggatct cctgcatgaa acatgcgatt ctcccctgcg taaatgccca
    10081 catgggtcac ataagtaccg gcatcatagg ttgaatgaaa gaaaactaaa tcacctggtt
    10141 tggcatcttt tagatcaata tgagtcatgg catcatattg atcctgagcc acccgaggaa
    10201 gtttcaggtc aactttggca taacaccatt gggtcaagcc actacaatca aaccccgttt
    10261 ctggacttga gccaccaaac acataggccg ttccttcata cttaaatgcc tcatcaaaaa
    10321 tttcttggac tattttgtca tcaaactgag ttgtagttag gtattgcttc actaataaac
    10381 agtaaaacat attgccataa ttataccgcc acccaccatt ttccttaatc gcgattgggt
    10441 tggggtaatc gactttttga ccacctgatt tttcctttga aaaagattca gctaaagcaa
    10501 aactatgctt cttcccgttt ttcccgacat gatctagata cccgccacca tagttatagg
    10561 cctgaataat actatcttga tcacacccta gttctttgga acgcttaacc aaagacgcaa
    10621 aatagagaca gccttgtttg atggatgcct cggtacttaa tgaattaggt ggtaatccgg
    10681 ctgactcaga actttgcata acgtcttcca ttgtgccacc agattccact tgaataatcg
    10741 ccaaaagaat tggaatatac tctgttatat ccgattcttt ggcatacttt tccaccattg
    10801 cacggtgttt caatacttct tctgagacac tagttccgcc aggagaagtg ccagaactac
    10861 catttccctc actgtcttca ccaaacaaca aacccacaca catcaaaata cccataaaag
    10921 agatggtcag aaaagttaat gaaataacac ccactttctt caagttcatt ttttctcacc
    10981 tgaccttgat tttggacgat ggttcattct tttttgtact ttttgattgg tctgctttgg
    11041 cagagtggac ctctgtttca cttgttggaa agaatttttc ttacttgctg attggctttt
    11101 cccttttgaa atgatttctt gactagttag ttttcgtttg atttcgggat tcagatttgc
    11161 tctcacaatc cgctttggtg cttctttttt cagcatcata tctttctgag gttgagctgc
    11221 tttatctatt ggaatattcg cccttctttt tccctgacga tttgttgctt cactcagtat
    11281 cttgcgtttt tcgtccattt tcgcatttct tcgttgtcgt tgtttttctc gcaaatccac
    11341 tcgatccgct ttttcttgga acagtccgcg cttgaattct tctggtgctt ttttcgactt
    11401 ttcgattcct ttatggagat tgtatttcaa attcgttggc gtattcctta cctgatcctt
    11461 tacttgttta gtcttatctt tcaccaaagc ttgggtatcc aaaactttgc cgatttttct
    11521 cccagccaaa ttcattcggg attgtttctt attatttgaa actggattct ccttagttaa
    11581 gtcagatagt atttcgtgat cgttcggtaa tcgtgaattc tttcgtagag aagaaccgga
    11641 tggcttaaat ttggattttg attgttcctt tgccaactta tttccgactg ctgcaccacc
    11701 accaaaagcc aaagctcgtc ccacatttcg attgagttgc cgcaattttc gattcattaa
    11761 catttgcggt tttcgcatga cgcgtcttcc cattgactgg ctatcattac tctggaggtt
    11821 gaacatactc ataatgtcgc ccaatttgaa atagataccg gcaaaggtca caatttgcag
    11881 aaaagcaacc atgaaaaatg gataggttgc cgaaatattg aaaaacatcg tggagatgct
    11941 aaatgcagtc gtaatcacca aagtaacacc cgctcgcatc ataatcgtat tgaataaacg
    12001 aataatcgcc ttctttccta aactttcata agtcggcaac atggacaata agaaactaat
    12061 tggcagaaac atcgcaaaga taatgaagag aatttgcgag aacaacataa tccctgttag
    12121 aagaaaaaca aagaaggaaa tgccaatatt gaacaatacc aaaaagacca cggtccctaa
    12181 acggttcatg gtcttggtaa tactgagatt cgcattgtca ttgtcttcaa tctctgcctt
    12241 gaccgcttct tcccgatctt tgcctttgtt ttcatctgga ctcacagata gaatcttgtt
    12301 gacccggtct tcaccaattt cttctatgtt ggaatcatca aattgcagta gtaaccaagg
    12361 ttgttggact tgaatcgaaa acaaactatc ccgaatcaaa tccacactat cttttccttg
    12421 gctttctgaa ttgggtacaa cgatctcggt tccaagggta agggccgctt cactaacatc
    12481 tgagctaaag tcattgattt ttgtgatata ggtaggcgca taagcaatga acgaacccga
    12541 tagtagaaaa atcatcacaa aattaatcac ggctcgaact gctttcgtgg tttctcgttt
    12601 taataatccg gtatacgcca catacacccc cagagctaaa atcatcaata atagaaaccc
    12661 aaaataaaat ccggaggtct ggagtccatt ttcagtaata ccagccaatg tttggatatt
    12721 ctttccaata ctttcagccg tatccgaaat gaaatctaat ttgtaagcct cttgaaccac
    12781 ataacccgtg gcgttcgaca aatacaaact caccgtccaa atgaaattag taatggcata
    12841 aagaccatac atcacgcttt tccctaagcc atcaccccaa ttccaaggca accaatccca
    12901 agagctatcc acaaagaaat ctagttgata gttgttcagt gaatatttgg aatatagatt
    12961 tcctgcttca actgtatcat caactagccc tgtcgcctcg gctaccgtac caactaaact
    13021 caatagaact atcagagtga gtatgctaat aaaaacgatt cccacaatcc gaaaaagttt
    13081 ctttttcatc ccctcactcc attctctctt gaacaggtgg acgggtatca aaggcatgga
    13141 agagttcttc aaagactgga tgtacctgaa ccacgcctac ccgaccatac aaatcctgca
    13201 tcaagcattg gccattttcc aaatctcgta ggcgtttttg attgctttca tcttctcgat
    13261 ccaagccaaa gaattccaag gttttcttga tttcatgaat atcggtactg cgaaacgcaa
    13321 acttcaaccc gatattattc ttcaagcgtt catccagtaa atcatcacta ttttgcgtga
    13381 caaagtaaac cccggcattc atagcccgcc cagcacgaac gagcttattc gataatgttt
    13441 tcccttgcgc tacttgaaga aaactccacg cctcatctaa gtctacaatt ttgaagattt
    13501 ctcgattact atggataaag tccaaggcaa aagtggaaat gacgattagc atggaaacac
    13561 taagcaattc catggtggta tattcttcaa aagtggtttc tgcatctggt aaaaccaaat
    13621 ccgctacttg aatgatattt aactgcctat ctaaactaat cgactgggta atcgaaccat
    13681 ctgagaaaag caaatgggca aaatcataat cggtaaagga ctcgatgtga tccgcgatat
    13741 tttccgcaac tggtgagcct tcttttcgaa gctcattaat tacttgtaat aatccccgtt
    13801 gattgctttg ggtaaccgtc cgaatggcct tacgcaacac tggaaacttc tccccatctc
    13861 gactagaaat tcctgttaaa aaggtcagaa tatcaattgc tagactttca gaatccttct
    13921 ttttctccat aatcacataa ggatcaagta atccttgatt ttttggctta ctagttaagt
    13981 tgagaatatt gatttcatcc gcaatttctg gcaaggtttc tttccagcca ccccgttccc
    14041 cttttggatc gacaatcaca gcttgtccac caaaaaggac ggcgtaataa actaagagat
    14101 tgttactaaa ggactttccg ccaccgagtg aaccgaggaa tgccgctgct agcgcattgg
    14161 taactgaacc cttgacccct tgtgaggcca atgccggttt caggtaaaca ttgcgccccg
    14221 tatctacgtt ataaccaaag taaatgcctt ccaactcccc taacatctga gtggcgccaa
    14281 aaccaagtcc ggcgagaaaa tcagacgtaa catactggat ataatcattc atgtatcgct
    14341 tactagaagg taagaattct tcatgtagcc ccatcatatc gccaaaaggc cggactagtt
    14401 ttacattggt atcatcataa aaatctagca cttcatcaca ccggcgcttt agttcatcta
    14461 ctgattcggc acttactcga accacatagc tcagtttgta catggattct ttggactgat
    14521 ccaaggtagt ttccaattca tctacggaat ccaatgcatc taagacattg gaatttgttt
    14581 cattgtcaga ttgataggca tggttgtcca agtcttttaa ttcctttttc ttattgcgaa
    14641 cggtagcaag tgcctttttg ttcgtcacaa tctccacatt catactagtg tcaattggga
    14701 atgtaaattg ttgttgctgg taatagaaaa gttctgagga gggaaactcc atttccccca
    14761 caattgtatt aattgttaag tacgctacat atgattcatg attctcatgt tccatgcata
    14821 agtaccgggg cttttcttca atcaaacaac gactgggacg taataagtcg taacgtttca
    14881 ccaaagtttc cgacttcagc tttttctttg gtagctgaaa ttcatattct tcaaatggtg
    14941 tacccttttc gccatagata tgttcaatca aatacatcag atcactcggt gtgactcgtc
    15001 tgactttaaa tcttcgagcc aatttacttt ccattagttt ttcaagcttg gtatatcggc
    15061 gaatttcttc attggataag gaaacaaaat cgcccatcaa atgatgattc actccataga
    15121 caaattcttg aaagccggag aagaaagatt tcttgagatt ctttagattg acctcttcat
    15181 ctgtcgcaat cagtttgaag ccaataaaaa agcgataatc aatctgacta tcgccaatca
    15241 tggatactaa tgcctctgtc tgtaaatcaa ttcgttgttt cgctacttct gttaatcgcc
    15301 cggtaatttc cttttttgat cgttcttgcg tggcacgaat actactttct gtggcaattt
    15361 gtaaggcatg aatcttgcct tcacgatttt gcgcaatcaa ttgacgaaag ttatcgtgga
    15421 cttgatattt ctgttcaggt gacaaaaagg agtaattgta aggtattaac tcatagtagg
    15481 caaaacattc tccctcttga ttaaagacaa gattattttc aatatactta atcgggtaca
    15541 tagttcacac tccttaccag agtaatgggt tcgtcccatc gtttcttctg ttctttgact
    15601 ttctttcctg cgaaagtgac cttaaatcgt aagtgatagc taataaaaga tcgtaaaaat
    15661 cccaatggtt tcttaccgtc aaacgttttt tgcgacatga accaagtaac tgccaccggt
    15721 atacctaagt attttaaaaa ggccccctct atcatagata gtggaggcac atgggcaaat
    15781 acgatgacaa acagcaagga taaaacaaac caagccatct ggttaaaagt cacaggaaaa
    15841 ggcagttgaa agtcattaat tgcataaatg accttttcaa ctgcccaaat actggtgtag
    15901 ctttttattt tcttcatcaa atcattcctt taaaaagaag gatagtttag aaatcaacta
    15961 cccttcaata attttgttaa tatggatact caaaaacacc tcgactcgtt accaaataat
    16021 tgcctccaat ctccaagtct ctaccacacg catcaaaatc aatatacgtc ttcaagtgtt
    16081 ctggtacttc tccaaaatca ccagcttcta caatcaagaa atatgctaca tcactcatat
    16141 catcgcaatc tggataatag ataatatcat ccacatgctc taccatctcc tcaaaagaat
    16201 tgaagaaagc atgttgaatc tcagaagcaa cttcaccaac tggcgttcct tcaagttcct
    16261 ccgctaagcc acacaaccga ttaatttcct caattggcgt atactcatca atctcaaagg
    16321 gaagttcata atcatgaatt gcatattcct cgtattcgtc atttaaccca attcgttctt
    16381 tcacttcatc aaaatcgaca ggtggggtaa accacgcccc caccaattca ccttcgttat
    16441 atttcccgag gttcgcaata taaacacgca tctgttccat cgtgcttccc ccttacgcac
    16501 cgacaattcg gttaaacaaa ctgagtaaga catccttcac cccagaagca ttaaagacca
    16561 atccgaccgc aatcaaagca atcaccaaaa agccaatcag tttggaaaac tcccgcttaa
    16621 atcctaaaaa caaaccaatg accacaattg ccagtaagac taaggattg
//
LOCUS       DACBZK010000060        16527 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.062, whole genome shotgun sequence.
ACCESSION   DACBZK010000060 DACBZK010000000
VERSION     DACBZK010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.062"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(141..416)
                     /locus_tag="IVD66_002052"
     CDS             complement(141..416)
                     /locus_tag="IVD66_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008214712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HAP6146254.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(659..1969)
                     /locus_tag="IVD66_002053"
     CDS             complement(659..1969)
                     /locus_tag="IVD66_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAP6146255.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(2151..3380)
                     /gene="rpsA"
                     /locus_tag="IVD66_002054"
     CDS             complement(2151..3380)
                     /gene="rpsA"
                     /locus_tag="IVD66_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HAP6146256.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(3515..4195)
                     /locus_tag="IVD66_002055"
     CDS             complement(3515..4195)
                     /locus_tag="IVD66_002055"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAP6146257.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(4244..4879)
                     /locus_tag="IVD66_002056"
     CDS             complement(4244..4879)
                     /locus_tag="IVD66_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP6146258.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(4945..6348)
                     /locus_tag="IVD66_002057"
     CDS             complement(4945..6348)
                     /locus_tag="IVD66_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HAP6146259.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(6335..7366)
                     /locus_tag="IVD66_002058"
     CDS             complement(6335..7366)
                     /locus_tag="IVD66_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146260.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            7397..7618
                     /locus_tag="IVD66_002059"
     CDS             7397..7618
                     /locus_tag="IVD66_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAP6146261.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(7783..8520)
                     /locus_tag="IVD66_002060"
     CDS             complement(7783..8520)
                     /locus_tag="IVD66_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HAP6146262.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(8673..10013)
                     /locus_tag="IVD66_002061"
     CDS             complement(8673..10013)
                     /locus_tag="IVD66_002061"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HAP6146263.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(10250..11773)
                     /locus_tag="IVD66_002062"
     CDS             complement(10250..11773)
                     /locus_tag="IVD66_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HAP6146264.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(12151..12762)
                     /locus_tag="IVD66_002063"
     CDS             complement(12151..12762)
                     /locus_tag="IVD66_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP6146265.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(12885..13010)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(13092..13808)
                     /locus_tag="IVD66_002064"
     CDS             complement(13092..13808)
                     /locus_tag="IVD66_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAP6146266.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(13814..14383)
                     /gene="scpB"
                     /locus_tag="IVD66_002065"
     CDS             complement(13814..14383)
                     /gene="scpB"
                     /locus_tag="IVD66_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HAP6146267.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(14367..15164)
                     /locus_tag="IVD66_002066"
     CDS             complement(14367..15164)
                     /locus_tag="IVD66_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HAP6146268.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFGTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(15134..15505)
                     /locus_tag="IVD66_002067"
     CDS             complement(15134..15505)
                     /locus_tag="IVD66_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAP6146269.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(15524..16411)
                     /gene="xerD"
                     /locus_tag="IVD66_002068"
     CDS             complement(15524..16411)
                     /gene="xerD"
                     /locus_tag="IVD66_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HAP6146270.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT         4645 a         3576 c         2798 g         5508 t
ORIGIN      
        1 aaaaattaaa taaaatacat gtgttttcta tgtatgacat acggattcgg aatctctgtc
       61 tcttatttat tccttttctg ctaggaaata aaaagaaaag cacttgtagc cctagagcca
      121 caagcgcttt ttcaactgtc ttatttaaca gcgtctttta atgctttacc tggtttgaat
      181 gcaggtactt tgctagctgg aatttcgatt tcttcaccag tttgtgggtt acgacctttg
      241 cgagctgcgc gttcgcgaac ttcaaagtta ccaaaaccga ttaattgaac tttttcgccg
      301 ttagctaaag catcttgaat agttgaaaat acagcatcta ctgctgcagt tgcatctttt
      361 ttagttaaat cagtagctga agcaactttt tcgattaatt ctgctttgtt tgccatggat
      421 agattcacct cctccacaag agatatgata gaaatatcat ttagttaaaa ctttctgagt
      481 ggtccagaag tttaaaaaga aatattgatt aacttcaata ttctgttatc acgatatcat
      541 atgaaccgct taatagcaag gtttttacca attttcacat gcttttttta gtcatagaaa
      601 cgtaacaaac gaaactgtct ttttcttttg aaaaaaaaac gtcgatatgg taaaatgcct
      661 attttctcct acgagggata attcggatgg acgtcccttc aaaagtaaat gcttttctga
      721 tttgattttc taagaaacgt tcataagaaa aatgcatcaa ttcctcttca ttgacaaaaa
      781 cgacaaatgt aggtggtttg acagcgactt gtgtagcata aaaaatcttc aggcgttttc
      841 ctttatctgt tggtgttgga ttgattgcta cagcatccat aatgatatca ttcaacacag
      901 ccgaagagat acgaagattc tggttcatac ttacttgttc gatcatttca ggcagacgtt
      961 ccaaccgttg tttagtcact gcagaaacaa aaacgattgg agcgtaatca agataccgga
     1021 attcatcacg aatctcttgt tcgaaatcac gcattgtatt ggtttctttc tttacaagat
     1081 cccatttatt cacgacgata ataattccac gaccagcttc atgggcgtaa cccgctactc
     1141 gcttgtcttg ttcccgaatc ccttcttcag cattcagtac catcaaaacg atatcagaac
     1201 ggtcaatggc acgcattgca cgcatcacgc tgtatttttc agtattttcg tatacttttc
     1261 cgcgtttacg cataccagct gtatctatca ttaagaattt ctgaccactt tcagaaacga
     1321 agtgggtgtc gattgcgtct cgggtcgttc cttcaatatc cgaaacaatt acacgttctt
     1381 ctcctaaaat cgcattgatc aaagaggatt taccaacatt tgggcgacca atcaaactaa
     1441 acttaatcgt gtcgtcgtcc tcttcttcag tctcttcaga gaaatacttc actgcttcat
     1501 ctaaaatatc accaatccct agtccatggc ttcctgaaac aggataagga tcgcctagcc
     1561 ctaaggaata aaattcatag atatcgtttc tcatttctgg attatctact ttattgactg
     1621 ctaaaatcac tggtttatta cttctgtata aaattttcgc aaccatctca tctgcgtctg
     1681 tcacgccttc gcgtccgctg actacacaaa tgattacatc tgcttcttca atcgcgattt
     1741 ctgcttgatg cttgatctga tccataaaag gttcatcgcc aagatcaatt ccgcctgtgt
     1801 cgatcacgct gaattctcga cctaaccatt caccttttgc ataaatacga tcacgagtta
     1861 ctccaggagt atcttcgaca atcgagatac gctcaccagc gatgcggtta aaaatcgtag
     1921 acttaccgac gttcgggcgg ccaacgattg caattgttgg atttgccata ttatttcctc
     1981 ctcacaagtt tccaatctca cttagtttaa cgaatgcatt gccaactttc aagcatagat
     2041 tgtcaattaa acgaagtatt tttattcctt attgaaatac taatcgcttt tcaaaagaaa
     2101 aactgagaca aaagcagctg ctttcatctc agtcacagat acaaaatcaa ttatttttca
     2161 gaatcatcgg ttgctttttc ttctacttct tctttcaacg catcacctaa aatgtctccc
     2221 atagtaaatc cagtattttc ttctggtaat tcataagact caacattttt tggttcttct
     2281 tctgaagctg gtttttcttc taaagctttg atactcaatg caatacgatg ttcttctgga
     2341 tggatctcta atactttcac tttcacttcg tcaccttcat gaagcacttc atgtggtgtc
     2401 gcaatatgtt tatgtgaaat ttgagagata tggactagcc cttctactcc agggaacact
     2461 tcaacaaagg caccgaagct tgtcaaacgt ttaactgttc cgtctaatac tgtgccaact
     2521 ggagcttttg tatcgatttc tgaccaaggt ccaggctgtg tgtctttgat tgacaaggaa
     2581 acacgttctt gttcaggatt gatagacaac actttgacat ttacatcatc attgacagcc
     2641 aatacatcac ttggttttgc tacatgacta tgtgaaatct ctgagacatg gactagaccg
     2701 tcaattccgc ctaggtcgac aaatgcgcca aaatcagtaa gacgtgcaac acgtccactg
     2761 agaacatctc cctcatggat agttgaaaga atttcttttt tcttttcttc tctttcgttt
     2821 tccactaccg ctttatgcga taagatcaaa cgattttctg atggttcgat ttcgatgatt
     2881 ttaaagctca atgttttgcc tttatagtct gaaaagtctg caacaaaatg atcttccacc
     2941 attgatgcag ggacaaaacc acgtacaccg acgtcaacga ctaaaccgcc tttgacaaca
     3001 tttgtaacag gtgcttcgat gaccttgccc tcttggaaat ctctttcgat atcttcccaa
     3061 acttttttag catctaaacg gcgttttgaa agtaggtagc tgccgttttc tttatctttg
     3121 ccgatcgtac tgataacgac taaatctaat acatcaccga cttttactac ttcgctgata
     3181 tcttctaccg gcaaagttga taattctttt gccggaacga ctccttcaac tccagcccct
     3241 tcgattccga caatcacttg tttgtcttca atgactaaaa cttcgccctt aacaacatcg
     3301 ccaactttta cttcttgtac gcttttcatt gcgtcttcca ttgactggtt gttctcttga
     3361 ttttgatcaa attctgtcat aacacttgtc ctcctaacca acattctgcc gtaagtacgg
     3421 tactgttttt agtttaattg attattcaaa aaaaataaag cgatttcgtt cgttttcctt
     3481 gaaaaaacaa ttgtttttca ttttttttct taatttaaaa aagaagataa ccttttttca
     3541 aaacaacagc ttttattgct gcaacgactt ctggaatcga tttgccagtc gtatcgatac
     3601 gaacagcatc ctctgcttgc ttcagcggag agacgtccct tgttgaatca taatggtctc
     3661 tttcctgtat ctctttcgtc agtgtttcaa gatcagtcgg aattcctttt tcttggttct
     3721 ctttgaaacg tctttctgca cgctcactta cgcttgctac taaaaagatt ttcacttctg
     3781 cattcggtaa tacagctgtc ccgatgtctc ttccgtccat gacaacgcca ccgcgttccc
     3841 ctatttttcg ttggacagca actaattctt ctctgacttt tccatgtgca gagacttcag
     3901 aaacagcttt tgtgacatct ggttgacgga tttctaaagt cacatctttt gatgctatga
     3961 atacatgctg tccatcttct tgttgcgaaa aagagatagg atactttttg atcagcgaaa
     4021 ctagcccttc ttcatctgaa aaagatacat tgttcgtaat agctaaataa gttactgcgc
     4081 gatacatggc accggtatct gtataaatat aattcaattc ttttgctaat atcttggcaa
     4141 cggtactttt cccagatgaa gcaggcccgt cgattgcaat actgatttgt gtcatgatat
     4201 aactcctttt tctcagaaaa aaagccgcaa agcgcggcta ttattattta attcttaatt
     4261 cttgaccagg gtaaagcata aagttgtttg gatctaagcc attcaattca aacaattgat
     4321 cagtggtgat ccctgcacgc tcagccactt gttttggacc ttcgcctgct tgaacagtcg
     4381 ttgttgaacc ggctgcagct gatgaagaag gtgttgtttc tgctgcattg ctgcttgaat
     4441 cccctgcttg ataagttgcc tcacttgagg aagtcggtgt tgtctctgct gcaatactgc
     4501 tttctgacgt tacacctgta tcttgagaca cagtagattc ttccgcgatt gtactagatt
     4561 ctactgttga agtctcagtt gactcctctt ttgttgtact tgtagaactt tctactactg
     4621 atgtcgaagt ttcagaagaa gttgctgctg ttgcattgtt gcttgatcca tttctgatcc
     4681 agaaataagc acctgctgga atagcgatac ataagaccag taaaatcaaa aatagcgaaa
     4741 gaaataatgt atttcctttc ttttgttgtc tctgagaact tcttgatgaa acttcatcat
     4801 ctgtatcgta gattggttgt tcccatggtt cttgtgtttc gttattttct gtagattgat
     4861 gtctatcttt tctgctcact gttttacctc ctaaactcta tcgtgtgtat tataccatag
     4921 gaaaaagtgt cttgtcctaa aaaatcaatg ttccatgttt tttttaaata aatttagtaa
     4981 aatcgtttcc caatgaagtt gttcagtctt agaaaaaagc ttcctctttg gcagaagttc
     5041 tgcttttgct ccatcaatat cacaacaatt ctgcggcttt tcggagagtt tttcgccaaa
     5101 ataagctaag atgaattttc tgcggcagtt ttcttcatta atatagcgaa gcatctgctg
     5161 caggcggaat tctttttctt tttcctgacg tttgagccgt tccacccaat tttctggttt
     5221 ttcagactgc tggatcagct ccatccattt tttttgcagc tcatcaaagg gagcttgctt
     5281 tgtggcatat tccaaataaa gctcaaaact ttgtcgctgt tctctagaaa gttgattaaa
     5341 gaaataatgg atacgttcat ccccactttg ataaaaaaga attgctgcac tttcttcctg
     5401 atctctgcct gctcgaccga tttcttgtac atagttttct agactgtctg gcaaatcata
     5461 atggaccaca taacggatat cagatttatc gatccccata ccaaatgcat tcgtagcaat
     5521 gagaaactgc agctgatttt ttacaaactg ctgttgaagt tgtcttcttt gagctgcatc
     5581 aagaccaccg tgatagtatc caactgtaaa acgttccctg aataaatgat acaatcgttc
     5641 gacttctttt tttgttgcac aataaatgat tgccgctcct tgtgctcttt ccatgaagtg
     5701 ttcaagttct tgttcttttt gctgcgtttt ccgaacaaaa agcgagatat tttgccgatt
     5761 gactgattgt ctgatctctt ttggtggtcg atcaaatagt acatgacgta tatctcttgc
     5821 tactaaatct gttgctgtcg ccgttagtgc cagtgtgacc gggtttccta aaagctttcg
     5881 gatttttcct aactgttgat attctggacg gaaatcaact ccccattgag acacgcaatg
     5941 agcctcatct actacatata acgcaatatt ttgttttttc agatgctcta aaagagaagg
     6001 attagtcaac atttcgggac tcaaaaacaa aaatttatat tgcgatagat gacggaggac
     6061 gtatcttctt tcagattgcg aaagtaaact attgaaagca gctactcgtt tctcccctcg
     6121 tttttgtaat tgcgtcactt gatcttccat tagagaaagc agcggtgaca cgatgatgac
     6181 cagaccttcc attaaatacc ccgtcaattg atagcaaagg ctttttcccg ttcctgtagg
     6241 caaaatagcg agagtatctt ctccatcaag caacgcctga ataatttctt cttggccggg
     6301 acgaaatgaa tcaaatccaa aatatttttt taattcattt attaacattc tgtatcgctt
     6361 cctttctcaa tagatagatt tgatacaaac gaaattctcc ataatctaat tgtccatcta
     6421 cattccattc gctaaagcgc cactctcgca cggaatcctt atttggttcc aaacgttcga
     6481 ttgtttctgc agagagaatc cactcgtatg gaaaatcatc aaaaaacaag gcccactcaa
     6541 taagatgatc tgttactgtt cctcttttta aatgacggat tgccatgatc tggtcaattg
     6601 tctgaccatt cataaacatc tgcttggtga tcatcatgct ttgattgaaa ttttgctgta
     6661 ataatgaatc gatcaaagcg tgccaaagcg aatctggccg tttttcgatt tgtgctaaca
     6721 aaaggtggat acatctgctt tgttgcagat aaacctctga ctcatcattg ttttttgcca
     6781 gctgataagg aagcagccct gttcgctcat ttccagataa ttggttagct aaaaaatctg
     6841 ctgcttcttc tggtatctcc gaaaacagct gcaccaaact ctcatacgca gtatcaatca
     6901 aaatttcacg tggcaattgg ctttcactaa gccatttttt tagttggaaa gtataaaaag
     6961 gacttgtctc tgctggaaga tagtcttgaa tacccgttgc cagattagaa attacttgaa
     7021 cagcaaattt aatgagccgc caactagttt cccctgttct gccatagcgg tcaaaacgca
     7081 aaccagtatg ttctatttga tgttcggaca acatatcagc ccctgcaggc gttagctttg
     7141 cttcattttc atttatttcg atccaacctt gctgcgcaat tttttgcaaa atttgataaa
     7201 acttatcctg cttcaattct ggaaaactgt tatggataaa caaaagttcg tgggtaaatc
     7261 cataaataag tactgaagtc gttcgttttc ccacaaggag ttggtaaaga gaactaatcc
     7321 gcagcttgtg tcctgatgaa aatagcgata aaataaaaac aatcatatta ttctccttaa
     7381 gttaggatgg ttagaaatgt cactactatg taaacttgta cctgaacgct gtattgcatg
     7441 cggtctttgt caaatcgaag cgccagatat tttcgattat gatgaagaag gaatcgtttt
     7501 atttgcccaa gaaccagagg ctcatcaaca gttcgtgatg ccggaagaag aaacatatgt
     7561 aaaaaaagcg tatcaaaaat gtccagttcg agcgatttta ttagaaaata aaatataaat
     7621 ataaacgaaa ctttaaaaac gtacactaag ttctctaaac ttgaaaataa gccgggatct
     7681 gtttctcttg ttccgtgaaa tcccgactta ttttgaaaga ttcatttgct atctatagtt
     7741 aattgactag ttttttcacg gaccctatag gacccattta tattatttca actttttcag
     7801 ccagttttcc aatgtattga cgatcacagt ttgctggtct gcgttagaaa tttctgcctc
     7861 tccatctcct ttttgctcac catagctgcc aaaacctcca tgatttccgc cattgattga
     7921 tacatactct gttctttccg gtaaatactg cttagcttct tgataagctt cctgattcaa
     7981 tactttatct tttgtcgccg tgatcgataa aacaggaaca gctgattctg tcaatgttcc
     8041 ttttttgtcg ggataacttg ccatgaagaa tacccctttt aaatgtttgt ctgaatgatt
     8101 cttattgaca taacgacttg ccattacgcc acctaatgaa tggccaccga tcacataatc
     8161 ggaatttgga aaatcttctt tgaccttatc cgctttgttt ccgcccatca ctgctagatc
     8221 aagtggcatt ttgacaatag cgactgaaaa gccgtttttt gctaaatctt gcgcccaaat
     8281 actataactt tctggctcta cgagagcacc aggataaaaa ataagtaatg gagactttcc
     8341 atgattcttt ttctctcctt caaaaaataa gtaatcttct ttgttttttc cttcttttac
     8401 caacacttgc gcttctgacg atggttcgta cgtattttgc tgtatatagt aataaccggc
     8461 tccaccgagt aatcctaaaa tgatgactaa gccaattagt attcgtctaa atattttcac
     8521 tttctcccac cttttctatc tgagtgaccc ctttttctta atcaagtatg attatacctt
     8581 aaaaaaataa gagagaaatg caaactttcc agcatcaaat aaaaaaagac ggaatatcca
     8641 tttgaatatc cgcccttttt gtatgtttat ttttatttag cacataaacg atacacagct
     8701 tctgcataaa tttccattgc tttatacata ctacttaatt cccatcgttc attcgcctgg
     8761 tgcataaagt caggagtatc agggaacatc gcaccgaatg ccacacactg gttcatcgta
     8821 cgagcaaaag tagcgccgcc tgatacaaac ggttcagtca tgtctccagt aatatcgcga
     8881 tatgtcccca atagattttt cactaactca ctgtctagtg gcacgtataa tgaatcaagg
     8941 aagtcaaatt cttcataagt caacccatat ttttctgctg ttttagttaa tttagctact
     9001 aaatcatctt tcttgaatgt aacagggatt ctcatatcta caccgatttt tgtttgttct
     9061 ggtgtgattt ccaaacttgc aaagttcatc gttagctcgc cggattgttc atcttctgtt
     9121 ttgcccacga cagcttcacc agttgcattt tcttgaacta attttcctaa gaaattgatt
     9181 gggccaaaat caaatacttc tgaaagagca attgccagac gagaaatagc attcactcct
     9241 tgtgctgcat ctttcgcgtg gatactttta ccaagaacga cgatgccttc accttgttct
     9301 tcgaaatcga attcgtgttt tttcaatgct tcttttactt cagaaagctt ttctccagag
     9361 taaggagctg catcaggaac aacattcaac gctcctccag cttttacaga aaactcgttc
     9421 gttcctggtc ctgtcaagta agcttgcaat aagccttttt ctgcataaat taaaggaaat
     9481 tcagcatctg gcgcaaatcc ttgcgtaatt ccttcttctt tttcgttata tttttctaaa
     9541 caacgccata aattttcttc atctgtacca aagataaaac gaatacgtgt cttgaattcc
     9601 acgccagcat caatcaaagc tttgacggca tacattgccg caatagaagg acctttgtca
     9661 tcttgggatc cgcgaccaac taaccagccg tcttttatag ttggatcgaa tggttttgtt
     9721 tcccaattat tttcgtcccc tgctggaaca acgtccatat gacacaagat accgaataat
     9781 tcatctccag agccaatctc tgaataaccg taatagcctt ctggatcttt aaatgttcta
     9841 aatcctagct tttcactgat ttccaatact ttatccaaag cttcaatcac ttttttaccg
     9901 aagggatgtc cttgtcctga atctgcttca tctagtacgg aaggaattcg gatcaattcg
     9961 ctcaatgatt ctaatgcttg ttcatgatgt tgttctgtca caaatttttt catgatatta
    10021 tcctcctaat atgttaaaaa gggtcatgtc aaattcctcc gacacaacct cttcttctca
    10081 aataatgacg ttttaagcct gctccatcag caagcagaat gttcttaaca aatgatgaaa
    10141 gaaaaaacac tcactgaatg gagctattga cttgtccacg tgcttatcga tagccgttta
    10201 tcggtttctt cattcttatg atagaccttg tacttgtatt tgtctaggtt tagaacattg
    10261 ctgctacacc taggatcaca cagatggcta caaataatat cgcaattaat ttaccggtaa
    10321 atttccacca cactgaaaca tcgaaacgag caattgctac agcacccatt acgatagcag
    10381 atgttggtgt aattaagttt actaaaccag atgcagattg ataagcagtg attactaaat
    10441 ccttaccgac gccggcaaat tcacccatag gtcccatgat tcccattgtt gcagcagcta
    10501 agccggaagt tgaaggaatc aagaatgaca tagggatata gaaaataaat gtaataatga
    10561 tgaatacact tgaagataat gaacttaatc cttgttcgcc ccaatgtaag atggtgtctg
    10621 tgattaatcc attgttcata accacttgga taccacgagc aacagctact acgattgcta
    10681 caccgatcaa atcagaagca ccagctaaaa attcagagac aaattcagac tctttcatgc
    10741 cataagtgat tgctactacg atggacatta ctaagaataa catagtaatt tctgggaagt
    10801 accagtcacc taatggaagc atgcttttac ctagaaccgt acctagtacc ggaaggtttg
    10861 ttaaccagtt tgtcaatgat tcaaaaatcg tgaaattcgc attcaaggtt gtccaaggaa
    10921 tcaaactgat gatcatgata ccaaaagtaa taaagaacaa tacattaaca tgtttttgtt
    10981 ttttcgtgat tacttcttga cgaccgattg cttcaatatc gaaatgcttc atatcttctt
    11041 tacgttggtt gtatactaat gattttgttg gatctttttc gatctttgat gcataacgat
    11101 acacatatac aatagaaata gctaacaaaa taacgaacat caagaatcga agaccaatac
    11161 cttcacccat cgaaatccca acagcttgtg aagctacgcc tgttgcaaaa ggatttaccg
    11221 ttgaagctag acagcctact tgagacccta ctaatacgat tgctacagct actactgtat
    11281 caaagcctac agccatcatg actgggatca gtaaagcata gaatggaatc gtttcttctg
    11341 ccattccgta agtagagccg cctaatgcaa ataacagcat caatactgga ataagcattt
    11401 tttcttttcc tttgaatttc ttcacaactg aagcaatccc ggcatctagt gcccctgttt
    11461 tgttgataat acctaaaaat ccaccaacaa ccaaaatgaa gaaagagatt gggattgcag
    11521 caggtgtttc tttagttagc tcccccgctg gtacacctag catcccattg attggcgcca
    11581 tgaaaatatc ccacagccct tgaggatttt gttgtactcg ttcatatgat ccagcgacga
    11641 tgttgcctgc atcgtctaca ctatagtgcc cagctggtat aaaccaagta agtacagcga
    11701 ttactgcaat aataataaat aagaccgtat acgctgaagg catttgaaat tttttctttt
    11761 ttgtttgttc catcttcttc ttcctttctt ttccgttaga gacaacaatt ttggctctaa
    11821 tgttatttta tcaaaaagag tatcagaaca aaaataataa cacgcatttt gtaaaacttt
    11881 tgttcaaaaa gttcgttttt ccctattccc tcctcttttt tcaggttttt aaagctttct
    11941 tctttttcat tgtagcgttt cctttttttt ataaacaaac attttcgtct tttaaaagga
    12001 gaagaatttc acatttgcaa agaattgatt gatttttatg cataaatcaa aaaaatactc
    12061 aaaacaaaca aataaaacgt ttacattatt gcatgtcttg tatttttttc caaaaaaaaa
    12121 gaccaagaaa tttcttgatc tttttgatat ttatttgact gctgtatgac gttgttcgaa
    12181 ctgatgttgt tttcgactta accatggaag aagttgcgca tgcagcacta aaaagacagc
    12241 actcacgatg aatcctttga tcaagttgaa aggaacgatc ccaatcagta catagtttgc
    12301 taaagacatg cccagcatct gtgttgcgtt cagccctaaa aacattaagt aaagaggcgt
    12361 aataacgaaa taatttgcga tactcataaa aatagttaga gcgatggttc ctgtaatgac
    12421 acctaaaaat ttgtttcttc ctttatgctg tttctttaca ctaaagaaat aataaatcgg
    12481 gaatgtaaag atcgttgttg ataagaaact agcagtgtct cctaccaaat tatccggaga
    12541 aaaacctgta gtcagcagat gtaatactga acgcaagaac gctgttgcaa ctccggccgc
    12601 tggaccgaat aagaacatgc tgatcaatac cgagatatca ctaaaatcga tcttcaaaaa
    12661 actaaaagcc ggcatgatcg gaaaagcaaa atactgtaaa actaatgcga tcgcagcaaa
    12721 catcgctact gcaaccattt tctgtacacg ggtgttcttc atttgaaatc ctcctgttag
    12781 gactcctctt cagcgaactt tttgacgttt ctctccaaat gaaaaaactc tattttccag
    12841 ggaaaataga gttagagtta tttgatcaag cgtcgtcaaa taagctctat cttctttatc
    12901 cagactatac tgtcggtatc ggaatttcac cgattcagct atttttttgc aaaataggtc
    12961 gtggactata accaccggtc gggaatttca ccctgcccct gaagacgaac cttatataat
    13021 ttttgtttac atattcatta tacatatcta ttcaaaaaac gcaacatcta acacttataa
    13081 aaagtaagtg ttcattttga gtggttcagc aaactgctga cttctttttt gttcagttca
    13141 cggtaatccc caggacgtag gccttgtaaa gtcagatctc cgtatttttc acgttttagt
    13201 ttttgcacag gaagaccaac tgcttgaagc atatttttca cttgatgatt acgtccttcg
    13261 tggatcgtca attccacgat actgtggttt gtcttaggat ccactgataa aatttggaat
    13321 ttagctggag atgtttttcg tccttcgatc tttattcctt ttgtcaaagg tgcaagcatc
    13381 gattttgtag cgatcccttt tacctttgca acgtaaactt tatccacttc atgttttgga
    13441 tgtgtcaggc gctgagcaaa atctccatca tttgtcagta gcaagatccc cgaagtatcg
    13501 taatccagtc gacctacagg atagatacgt tcttttacca tcggcaaaag atccgtaaca
    13561 acttttcttc ctttgtcatc tgcaacagca gaaataactc ctttaggttt gtacaataaa
    13621 tagtaaccgt attcttcttg ataaattggg acttcatcca cttccacagt gtcatgtttc
    13681 ccaactttta tccctaattc ccttacaact tgtccgttta cttttacacg tcctgcaagg
    13741 atgaattctt ctgcttttcg acgagaagtg atgccagcgt gggcaattac tttctgcaat
    13801 ctctccatta caattattct cctttattca ttccatcaaa gaatagatct ggtgacacgt
    13861 cttcttcaag tgaaatttcc atttcttgtg tatcaggcag ttcttctaat gatttcaaac
    13921 caaaataatc taagaagtag ccagttgttc catataatat cggccgacct ggtccttcta
    13981 ctctaccttt ttcttcaatc agtttatggg cagctagacg ctgtaccgct cctgaaacct
    14041 gaactcctcg aatctgctcg atttcagctc ttgtgattgg ctgtttataa gcgatgattg
    14101 ctaaggtttc gacggcggct tgagataatg tgtttgatgt cccttgcgca tatcgcttaa
    14161 gtaagggagc cagctctttt ttagtcgtta atacataatg gctttccgtt tcaaaaatat
    14221 gcaaagctga gtgcgagttt tgagtgtaag attcttttaa ttctttcact aaacttgtga
    14281 cttctgcttc gctgagattt aacagtccgc ttaattcttc attactgatc ccttcctcgc
    14341 caacaataaa aagaagggct tcaagttcac ttaatttcgt catgttcggt atctcctact
    14401 gctggataaa gcataattga ttcatagttt tctttttgtt gcgcaatgat ctgccctttt
    14461 ttcatcaatt ctagcaaagc cataaaagta gtgacaactt cacttttaga aggtgactca
    14521 aaaaaagaat cgaaagtaca gccatgcgca tttcttttta tacgctcttc gataaatacc
    14581 attcgttctt cgatcgttgt gtcatcgggc gtgatcgttt tttccacttt ttgagaaaat
    14641 ttcttacgtt ctaagatttt ctgcatggca cggatcaaat cgattttttt gacttgtcct
    14701 cgcttcaacg gcttttcagc atccgctaac ccatcgatgt tcataggttc ttttgtgtaa
    14761 taaagacttc gttcctctgc tttttctgtc agtctttcag ctgcatattt atatttacgg
    14821 tattctaaaa gctgagtgac caattcttct cgaggatctt cttcccataa ttcttcatcg
    14881 tctgtgccga attcttggac aggaagcaat gtcttgcttt tgattgccat caatgtagca
    14941 gccatcacta agtattctcc tgcaacagct agctcgagtg ttttcattgt atggatataa
    15001 ttcatatatt gctccgtgat cgtagcgatc ggtatatcat atatatcgat ttccatttgc
    15061 tgaatcagat gaagcagcag atcgagagga ccctcgaata catctaattt aatattgatc
    15121 tccgtcaact cattcactct ttcttctttt tctttgctag ccattttcca atgtaaggct
    15181 ctgtgatttc agttgcacgg atggagacat ccgggtactt ttcctgtaat tcatctaaca
    15241 tttgaaagcc catattctca ccgcgataag acggattcaa agaaatgtca tggatgatca
    15301 gctgatcgtt cgttgcccag taaataccaa taatcccttg aatgttggtt gaaccttctg
    15361 gcgtaaagaa aaaaagttca taatcgtctt cagattcgta cgtatcaatc tccttcaaca
    15421 aagaagtttt acctgtcagt ttcttatgga aactcaatag tcccatagca attttacggt
    15481 tttctttccg gtaatgtgtt aacatcttct caccttccta tgactaagcc cttggaaaat
    15541 gctgcttata aacatccgtc attcttttct tcgtgatatg tgtataaatc tgagtcgtag
    15601 agatatccgc gtgacctaac aattcctgta ctgtccgcaa atcagctcca ttttctagca
    15661 gatgtgtggc aaagctatgc cgcagcgtat gtggtgttac ttctttgtaa atcccagcct
    15721 ctcgtactaa ctgcttcaga tttttccaga ttccttgccg agaaagacct ttcccatgat
    15781 tattgacaaa tacatgcatt tcagatgcgt cctttacaag taatggacgt gcttcgtcta
    15841 agtagcgttc cagccattgg atcgcataat cacctaaagg aatgatccgc tctttatctc
    15901 cttttccaac tgtctgtacc agtccaagag aaagatgaag atctcccaat ttcaatccaa
    15961 tcaattcact gacgcgcatc ccagtagcat acatgacttc caagattgca cgatctctta
    16021 tccctaacgt ttttgtcgta tcaggtgctt caatcagctt ttctacttct gtcagagtca
    16081 atgtacttgg taatttctgt gctttcttcg gcgtatcgat atgttgcatc ggatcatgat
    16141 cagtgatacg ctcttgccgt aaaaactgat ggaatcttct gagacttgag atcatccgag
    16201 taacagttgc tgtcgctttt ttttcttcat gcaacttctc cagaaaacgg atgactaaaa
    16261 agcgatcgac atcctgccat gaagcaattt tctgctcctg tagaaaatgc aagtactgtt
    16321 ccaaatcacg ttcatagctt tgtcgtgtat tggcggacaa tccccgttca atattcaagt
    16381 agtggagata atcgttgatt tgctctttca taataatccc cctcatgcct ctctatcata
    16441 tcagataccg cttcattctg atagtctttt tccataatct gagcaaagaa aaagccgtct
    16501 agacactcag acggactggt ttctttt
//
LOCUS       DACBZK010000061        15471 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.063, whole genome shotgun sequence.
ACCESSION   DACBZK010000061 DACBZK010000000
VERSION     DACBZK010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.063"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..1126)
                     /locus_tag="IVD66_002069"
     CDS             complement(<1..1126)
                     /locus_tag="IVD66_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAP6146271.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRD"
     gene            complement(1209..1544)
                     /locus_tag="IVD66_002070"
     CDS             complement(1209..1544)
                     /locus_tag="IVD66_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAP6146272.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            complement(1554..1928)
                     /locus_tag="IVD66_002071"
     CDS             complement(1554..1928)
                     /locus_tag="IVD66_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP6146273.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            complement(1941..2255)
                     /locus_tag="IVD66_002072"
     CDS             complement(1941..2255)
                     /locus_tag="IVD66_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP6146274.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(2368..5595)
                     /gene="fss3"
                     /locus_tag="IVD66_002073"
     CDS             complement(2368..5595)
                     /gene="fss3"
                     /locus_tag="IVD66_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAP6146275.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVALVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            complement(6009..7175)
                     /locus_tag="IVD66_002074"
     CDS             complement(6009..7175)
                     /locus_tag="IVD66_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6146276.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            7200..7526
                     /locus_tag="IVD66_002075"
     CDS             7200..7526
                     /locus_tag="IVD66_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146277.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            7679..8731
                     /locus_tag="IVD66_002076"
     CDS             7679..8731
                     /locus_tag="IVD66_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HAP6146278.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDSSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            8807..9025
                     /locus_tag="IVD66_002077"
     CDS             8807..9025
                     /locus_tag="IVD66_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146279.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            9012..11585
                     /locus_tag="IVD66_002078"
     CDS             9012..11585
                     /locus_tag="IVD66_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146280.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKF
                     DSNHETVIIDSEIRENDKGSKSRRRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSC
                     N"
     gene            11576..11773
                     /locus_tag="IVD66_002079"
     CDS             11576..11773
                     /locus_tag="IVD66_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146281.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            11777..12388
                     /gene="mobC"
                     /locus_tag="IVD66_002080"
     CDS             11777..12388
                     /gene="mobC"
                     /locus_tag="IVD66_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HAP6146282.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            12373..13764
                     /locus_tag="IVD66_002081"
     CDS             12373..13764
                     /locus_tag="IVD66_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP6146283.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            13980..14294
                     /locus_tag="IVD66_002082"
     CDS             13980..14294
                     /locus_tag="IVD66_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146284.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            14287..14781
                     /locus_tag="IVD66_002083"
     CDS             14287..14781
                     /locus_tag="IVD66_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146285.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            14849..15163
                     /locus_tag="IVD66_002084"
     CDS             14849..15163
                     /locus_tag="IVD66_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146286.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            15262..>15471
                     /locus_tag="IVD66_002085"
     CDS             15262..>15471
                     /locus_tag="IVD66_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP6146287.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
BASE COUNT         5204 a         2602 c         2782 g         4883 t
ORIGIN      
        1 gatcgcggat tccgtctcct aaatatttcg catccggcct ttggcaagcc aaaatcagaa
       61 agaaaccaga ttgacgaccc aacatcacga tttgtttgag cttattcaaa atcaccgcac
      121 tttctttcgt cgttaacatc tccatataag ccacgtattc atcaaagatt aaaaagttgg
      181 gtggaagtcc aagataggca taattctctc ctgttttgta gttagacatt tctttcattg
      241 ccttgctacg agccatcata cgttcataga aatcttccac acaagcagaa atttcttcct
      301 tttgtgaata aacatgaggc atcaccgtac ctaaatcagc taaatctgca tttttgggat
      361 cgaggataaa caattctgca tctgacttca atagtgcttc gataatggtg aggaggaaat
      421 aggtcttccc tccacccgtg ccaccagcga ttaacatatg gggtaaagaa tcataagccc
      481 atacttgatt tttcatcaat cgcagagtcc cattttctgc cactacttcg tctatcccaa
      541 ttcgattggc gatcatatca tacagtaaag tatactccac ataggagtct ttgagttcct
      601 tttctactaa ctcacaatac agtccgcttt ctaacttctt ttccaatttt aaaagctgat
      661 cttggtattt cccaagtgaa atttgaacgc gaatagacag taatccatct ttcattcgat
      721 aatagatttt ggggaagtaa ctgatagtct ctctggttcg gctactattc aaatctttga
      781 aaaagccttc actttgagtt tgtttcactt cataccaatg gttctctaga atcatccgag
      841 ctagcttttg tcgatgccac aagcttcgcc aatgatcaag aaaaaagtga atataaagca
      901 atatcatagc tcctgaaaaa gcgagacttc caagcagaca tactaaatct tttatagacc
      961 aaacgatttc aatagtagaa agtgatagct tagaaatatc aaattgtcta aactcttgaa
     1021 aataaaagac gctcatccaa ccgatgaaca gagcgagtag ccagccaaga acaaagtgat
     1081 aaaccaagtg ctgatctcct gcgcgtatgc gatgtccttt gtacattttg atggtttcca
     1141 cctccaatcg aaaaagccca ataggatttc attaggcaat ttcaaaaagt tatgctagtc
     1201 atttactgct acgaggaggg gagttgtttc gtttcaacca attgatttaa aaagccttca
     1261 atagcatccg gcatctccac accaatttct tccaaaatgg attctgcctg ccgacataag
     1321 ttttcattta cttcgacaac tataaagaaa gactcttctt ctcctaacca gtctagtaca
     1381 tcagagtctt cttcactgtc gctattttct ccaagtaaac cttgatgtat aatcagaaac
     1441 attttttcat cagaggttaa tgctttaacg agttgttcct cagtcagctc gccttttcca
     1501 tattgatcga gacaatctaa aatatgttca acattaattt ccataatctt cacctatttc
     1561 tttctttcat tttggttcgt aggatttcct tgattcggct gccgcttcaa gactaaatca
     1621 tccgccttaa tgaaccaatt aacggtagtt ccttctcgaa aaacataatt ggcaacggta
     1681 tccacgattg gattgaccaa ctctacctct gcatcataag caaactcgcg taagggtaca
     1741 ttagctggga tactaacttg aatcattcgc ccttgtgcag aggattttaa attataggtt
     1801 cgttctttta cctcattacc aattgttcca tcctcatttt gcttccgtac ttctcggcgt
     1861 aatgcggaaa aacgcaactt cccaaatgtt aaacctgaat ctacgacaat accttctgtt
     1921 aatctcatct tcttttcctc ctatgctttc actaaatcat caacatacaa cacgtaatca
     1981 gtaaacccac gattctcaat ctcatagcct ttggcaacca aatggggatt cacggctttt
     2041 agcggttggt cttgatcaaa atccttttca ccggcttccg cagctactac cacctcaata
     2101 tcatcggccc gttgcttact ggaatacaaa tgataactgc gaccaatcac cgtagtattc
     2161 cgtccatatc cttctgttat aatttctcct tcaccggcat aacttaactt tccaaaggtt
     2221 tcagccatat ctggcacgac aaatttcaat tccatcttct tttcctcttt tcattgttag
     2281 ttttggatac aaaaatagcg cgactacttt tttaggaggc ggtcgcgcac gttggttctt
     2341 aggatttact tgtatcatct catcacctta gttccggcga ttccagaaat aatagcccgc
     2401 cgtcgcaaaa atcaaagtaa aaccaatgaa cagtaaaaca ttggaatttt tctccccggt
     2461 ttgagggaag gtcttcactg tgggactaga ttcttgagag ccacttggaa cagttggtgt
     2521 ttccggttgt ttcggcgtac ttagtatggt tggaacttct tttggtgtta aggtttgaga
     2581 tttttctttc aaatcttcat tgtgttttcc attgatattc ccatctttat cgtaattgat
     2641 ttccgcaaaa gtaaacttgg ttccttctgg atattttccg gtatctactt ttttcgcaag
     2701 cacagttttg gtgaattctt tatcatttac ttcataatca atcttgccag atttccaaat
     2761 ttctttgttt gtaccatccg gtaataaagc atacagaatt gtttcgaaag cttcttttga
     2821 gccatccagt acatcatgag taatcgacac atcatcaaac atatccacca catcaccatg
     2881 agtaaaggtc tgagaaccgt tttctaggtg ggcctttgtt tggatagaaa catggtgttc
     2941 cactgtacaa ctgacagttt gggcttggtt attcaagcta acatccttcg ctactggctt
     3001 atcgcctgct tcaaaagctt ccttattttc atacacatag ttgaataaga caatagtttt
     3061 atttaaaact tgttcggcgg ttaatttatg ctgaattttc caagttcctg ttttctcttt
     3121 gttcgccaac gttgcgcttg tttctgcaat caccactggt ttggcttttt catctttttc
     3181 ttgggcagct tttgtcgcat ccacatcaat ggcttgcgct accacatacc agtcttcttt
     3241 gatttcatgt agattgtaac tcaatttatc aactagctcg gtagaatcca gagaagttaa
     3301 ttctttgttt ccgtctttcc aagtcgcaag agaagttaaa ctatcttctt cctcaggcaa
     3361 atcatagagc attaaacggt tcaaactaac agaaaatgct ttgttcgtca gcttctcgta
     3421 aggaacggtc accgttttaa ttggttgttt ttggtcttgt tcggtaatgg taaagacata
     3481 ctcactcttc acaaagtctt ctttgttttc cttaaaagta gaacggattt ctaatggcgt
     3541 aatcttttga aaaccttctg gggcttctac ttcttcaagt aaataatccc cataaggaag
     3601 attttcaaac ttgccataac catcaaaccc taattgctcg ttataagctg tggtcgcttc
     3661 atcttcggca cctgtgattt cattggtccc ttccaatggc gacactttaa aggtcagatc
     3721 attgaagcca gtttcggtag tgcccgcagc tgatccagca aatttaaaga aatcaaagcc
     3781 aaagcgaatc acttgttctt ttgccgtaac atttcgggta atcacggcat ttttttcgct
     3841 atcatccacc tttttgatgg atacaggata ctttgtttca tcaaggctat atccttcggg
     3901 cgcttttgtt tcttgccaat aatactcgtt gatagctaaa tgtttaacgg caacttggtt
     3961 cttttcgtct aaagtcaaag tgaccgtttc atcagaacct ttcgttccct tcgctaactc
     4021 tggtttaaaa gcctcactcc atttaacagc ttttccatcc ttagcagtaa acaaggtgta
     4081 ttcagcaccc tcaaagactg ccttaccttg tgctttatcc ccagtatctt tgtcttcttt
     4141 cgtcaaagtg gtttcgccag tgacttcttg attttgccct tttacgttac tggtaacaag
     4201 ggctacggtt tgattggcat acttcaattc gacttttaca ggtttgaacg tattcacgaa
     4261 cccatgacta gctttagttt cggtcacata ataggttccc aattccaacg cattagcaat
     4321 ctcttttggt gtttccgcat gaccgttttc atccgtggtc atttcttgaa cgatttcacc
     4381 ggttggactg tctttgcgaa tggcaaacgt attaccagct aaggaataat tgtcattcca
     4441 aagatcactc cctgtttcaa ctccgctttt atccagaatg atttgccctt tttcccgtgc
     4501 gttttttgaa gtcacgtaaa tggtttcgcc tgctttaatg gtggtagtca tgggggtggt
     4561 atcaatcgta taaggcgccg gtactgattt ttcggtaatg gttacttttg taccatgagg
     4621 aatctcatcc aatgtagcaa tgccttcttt gtcagtagtc acgtcttttg caggtaaagt
     4681 ttttccaaag tctaaatgga aaaccgttcc tggtacaaca tcacccgatt ctttatcgac
     4741 ttttttgatc tttaaagaac cctccgtttc cacatcaatt ttgattgtgt aggtattagg
     4801 tttatcaatc gccccggcca ttaaagtctg ttggccagcc tttttatagg cgacaggtgt
     4861 tccggtacca gcagatttct taagcgtcag cacaccactt tcttttgaat tggcatttgg
     4921 ggtgattatc aactgattac cattcacacg ataatcaatg tttgcggcat tttccacaac
     4981 ctcatcgaac tctgacaaat tcagattatt cgtatccgtc acagtagtcg attgccctaa
     5041 tactgtttta gccgtactat tatggaaggt tggtttcttc tgataatcgt caatggcttg
     5101 atttattttt gcctcaatgg ctgcgatatt tacggcacta ccatctgatc gttttattga
     5161 gtgaagggta tacccattaa cttcttgcca gatcatcttc tgtgccacaa tatgagtatc
     5221 tgcatctgta cctacttttt tccataaaac ggaaactaat ttggctttat cggacatatc
     5281 tggtaacggg tttttctcat agccaggagt gaactcattg taaatcggga ctcctggttc
     5341 aatacagaaa atatcttgtt taaagccgtt gtacactgca taatgcggaa cagtgacttc
     5401 tgacattgga cgaccatcac taaaagttcc ttcaacagca tattgatgtg ctaaatctag
     5461 ttctacggtt accgtttgtg gatgggtaat ttcatcagca aaagtaatcg taggagcaat
     5521 tgctccaaca attgcttgaa cagccaaact caaaatagtt aatacacata atttcttttt
     5581 ttgtttttta tacatgaaat gttctccttt caaattaagc acaaaaaaat aagatgctcg
     5641 cttgaacatc tttgtttata aagtcttttt aaaattttta ttgactgaat agaatggatt
     5701 tgagaatgaa tgagcctaaa aatttaatct aaaatacgaa atatactgcc tttaaattag
     5761 aacacatttt agaacacaaa catttcaaat ttaatcaaat ataataaaat atatttacgg
     5821 gaaaaccttt ataaatcaag gtttttcaaa cttattcaat gatacgaaga aaccaggtct
     5881 taagaaagca cgtaaagctt cacagttttc aaaacgttaa tcgttgttat accaacgatt
     5941 tcagacactt tctcattgcg agaaggtgtc tttttttcgt tctggtaatg agaaaggtaa
     6001 tgacaatatt ataaaccagt gtaagcaatg aatttttcta acgcatttcg ttgagctttt
     6061 tcagtaacat gagaataagt gttaagggta gtttcagcat ttttatgacc caatcgatct
     6121 tgtgtttctt tgatacttgc tccaccttct agtagaagag tagcgtgagt gtgccggaat
     6181 ccatgaatag taacgtgctt aaatttatat ttcttctcta aacgtttcaa tatattattt
     6241 gaatagtccg catgcaaagg ttgattaatg tcaccgtctg catttacata ggtaaagata
     6301 agttgatttt ttgtatttgt atttatgcca aactgcaaaa gctctcgagc ttgttctttt
     6361 ttccagattt ttaacatttc aatagtttgt gcatcaattg gtaatattcg ttcggaagat
     6421 atattttttg tatttttttg aatcctgaca gtttttcttc ttgcattctt ctcttcattt
     6481 cgaatagttg catagctctt tctaacatac attagctgtt cttcaaaata aatgtcagac
     6541 caatgaagag cagctagctc tcctttacgt ataccagtag taatcaaaag ctggaagatt
     6601 aaaatatgtt ttaaaggctc ttctttattg agaatatccc aaaaagcttt tagttcttct
     6661 aatgaaaagt aattttcatt ttctttcttt tcccgctttg gtagatttgt atttgccata
     6721 ggatttcggt gtaatagctc tgcaaaaatg gcatactcaa atatttgaga gctgtaagac
     6781 ttaagctgtt tgatattctt gaattttaaa gcccattcat tgactgcatt ctgacagtga
     6841 acaggagtaa tcttagaaat ggacttattc ccgaattttg gtagtatatg caagcggaaa
     6901 aggtcttttg tacgttgata tgtcgtttct tgtacacgat tcctataaga aggcaaccat
     6961 tcttcataca ctgttataaa caagtcatta gaaggcttat gatagccggt atcttcaatc
     7021 tcgacctttt ttcttgcttc gtgtaacttg gcttcttttt cagttttaaa cccttttttt
     7081 acatagtatt cttgctttcc attttcatct ttacgaacat acaagcggac actatatcgt
     7141 gcaccgcttt ttgttgtgta cttttgtatt gacataacta atctctccaa tctgataact
     7201 tggcgagttg gctgattgaa gaaatagaaa atgagaggag aaaaataatg gatgcaggaa
     7261 ttacagtaat gttagataaa caacaaacga atcaattgaa aaattatgtt tttgaaatga
     7321 caaaagaggc tattgatcaa gcaagaattg ataccggatt agaaagacca tttctaaaag
     7381 gaaaagagat ggctaaatat ttgaatgtat catatacaac ttttttgaaa tttaaaagaa
     7441 tgggattgcc agttatttta ttagaaaaaa tggagttgtt ttcaaaagaa gaatgcaaaa
     7501 aatggatatt gagtcatcaa atttaaaaaa cacctcgttt tttaaatttg atgaagtaga
     7561 aaaaattaaa aagagtgttc ccgtcagttt gcagatcggg ggaacactca ataataaagt
     7621 tctgagaaaa ctttatttga atctattata gcaaataaaa tcagaagcag gtgtgacaat
     7681 gaatgaaaaa gaagttgaaa gcttagttga aaagcaaggc tattctaatt ctgatatata
     7741 tgcagaatta tactatcaat atcctatttt tttaaacgta aatgaaaaat ataagaaaat
     7801 gaaactaagt tctaagttag tttatatgtt actaaaagat agaaatagac tttcattgaa
     7861 aaataacttg tatgatgaga atcaaaaaat ttttttgata tttgaaatca aaaatctcgt
     7921 agaaatttcg ggaatgtcaa aaaatacaat cttatcagca ctagatgaac ttcaaaaagt
     7981 taaacttctt gtgaaaagaa aaaatggctt caataaaagt aaaatgcaaa tgttcccaaa
     8041 tttttattat ttgttaaagc ctgttctgtg caaagatgat gtttataaaa ttaataagat
     8101 aacccatcaa gaaaatagac aaaaaaactt gatagttcaa aatttgaact atggaacaaa
     8161 tcaatattct gttgatagtt caaaatttga actatgcgac acatcaatga aaacaagaga
     8221 caaaaacaat tttgctgata gttcaaaaaa tgaactagaa ttatataagt cttataaaga
     8281 tagtaaagat attaaagaat cacataatga tgatcttctt gaatcacttt caactaaaaa
     8341 taataaatta gatgaagaat tgatcgaaac atttattgaa gaaaatcttc ttaaacaaat
     8401 atggggagaa agtattgtga attgcttaaa actggctagc aatagtgatt atcgtcaatt
     8461 cgacaactgg tacaaaaaat tcaaatatgc gattagatct gctgaaaaag aacaaaaaat
     8521 tcaactgaaa attatctatg aaatttgtaa taacaagtat tttgtagatc atgttagaga
     8581 acagctatca atgactttac gtgacttgat acgaagagca aaaacagatc atcgtatcaa
     8641 acaaaaagac gattatatct ttgcttctct aaaaaataaa gcgttagaac taattgaatt
     8701 gcaaatcagc gaaggaatag ataagcaata agaatagaat tgagtcaaat gaaatggagg
     8761 ggtatctcca cttcatttga gaactttgaa tataggaggg gttattttga ttaaaaatcg
     8821 tttaatagat caagtttggt gtctagatca aaatacagat agtctcgaat taatcgagac
     8881 tatttgcttc aacactatag ttctcgattt aagagctgaa aatgataatt gtgtaactca
     8941 tgtcataatt aatcaaaaaa tggctcagaa gctctctgag agcctcagaa aatgggctaa
     9001 gggaggtaac gatgaaaata attgaaaaaa agattgccaa taaaaaaata aattggttgg
     9061 ttgttaattt tcttgttctg atagctatga ttatttttac aagtaatatt gctcatgcga
     9121 gtattttcaa ttggtttgat gacacaaaaa gtcaaacaga gtttttgaat aattctcttt
     9181 atagacctta cctaaaaaag tacaatggag atttccttag tcagttcggg atttggctcg
     9241 gatgggctgt ggtaaaaggc atgtttactg tgacagattc gattcaaaat atgattccag
     9301 atgtgctgga tttgttcaat ttcattgaaa gtacagggct aaataatgtt tatcaatcag
     9361 ccgtaaatac aattgtcatt ggattaatga tcctttcatt gatgtttgtt ggttacaaaa
     9421 tgattactgg aaaaggaaca gtggatttaa aatcggttgg aatgaacgta gtgatgtcta
     9481 tagcattaat acttttaatg ccaaccatga tttctagtgg tattcaattt gctaaaacat
     9541 tttataagga ctctactacg attacaaatt cagatgacgg agtcgcttgg tcattgataa
     9601 aacaaggagt aacagattta gcatatatta ataaaacaga tcagtactca agcattgata
     9661 aaacggagga tcgaaataat ttaacacgaa aaaattttca acagacggat ctcacacaag
     9721 tgttaacgga taaagtgatt gataaattgg aaaaagaaaa tccaattgcg gacaatcttc
     9781 gttatgaatt agttgaaaat tctaataatg aatttgttgc tacaaagttt tctgacaact
     9841 tcttatcaac attttctgat agcttgaaat caggctatta ccgataccaa gcaaatctat
     9901 gggggatttc aattgggttg acagcgttag caatcgccta tgtgttcagc gcgtttgtga
     9961 tcattacagc aatactagaa cttgcattta aacgtgtgtt aggtgttctt gtttttgcaa
    10021 cagatattga gacaggacag cgttcaaaag ttgttctatc agatattcta caatgttact
    10081 taactgttgg gtttcaagga tttgggttat caatgtttgc tatgtttatc aattttctga
    10141 actcaggaca aggtatctca acaaatattt ttataaaaac aattgcttat atctgtgccg
    10201 tttttgtttt aatcaaaggc agtggaacag tcatgagata ctttggtgtt gatattggac
    10261 tcaaagaagg ctatgggcaa cttgcttctg cttttggaat gggcgcaatg ctgtttagaa
    10321 aaggatcaaa tggatttaat cgtgctaaag gaagcggaga aggagaagat cgaaaaccag
    10381 aaaagaattt cggcgaaact ctatcaaaaa aagctggcaa aactggaaga gctttgggat
    10441 atgcccatga acgtggatta tccggtttag cttcagatgg agctacaatg gctagtgaaa
    10501 gagcaacaaa accatttaag agtatgcgtg atatagctaa tgataccaag aataagttta
    10561 aagaaggttt agatgatggt acagtgtccg ctattaataa aaatagcaaa cctatgttag
    10621 ctaaaaataa agaagatgaa actggaaaat atgctgattc cgtgccaaca cgtctttcag
    10681 atagaaaaga tggtgctaaa gttgaaaatg ccgatagaat tatgtctagt tctgaacgta
    10741 tgcgtgaagc aatgaaaaat aatgctgaat cgaataataa tcctgcaagc gcaattcagc
    10801 aaaaagtcca acaagatatt gaagaacgta aaaatgctat gcacggtcaa gctaagtctg
    10861 ctgaagaatt aattaatcag aagcgtcatg aagcgaaata cacgcctgaa gcaatgaatc
    10921 gcgaggaaat aatgttaagg aaacgtgtag aagggcggac aggcgctaat attgacggaa
    10981 aagaagcgtt gaccaaagaa agaattcaag aagctaaaaa ttcaaataca ggattagaaa
    11041 aattagtcaa agaaaatcca caaaattcta caagtagtca tggtggccga tcagtagatg
    11101 tccgagaaaa tattcaaggt tcactgaatg gtcatgttgg acggaatgtt gatgtaagag
    11161 agaatttaca aagttcttca aatgctcaag gtactaagac aattgatgtt cgagaaaatc
    11221 tgcaaagtag cagtacaagt caaccaaaaa cagtagatgt tcgagaaaat gtacaaaatt
    11281 ctacaagtag tcaaggattc aaaacagtag atgttcggga gaacattcaa aaagatagtg
    11341 gagaaatgaa agaaaaaaca caaaaaatca atatcgttga agacagaaag tcagcgaaaa
    11401 aatttgattc aaatcatgaa acagtgatta ttgatagtga aatccgtgaa aatgataagg
    11461 gatcaaaatc aagacgaaga ttcacttatg aagacaatga gttattcaga gatacactta
    11521 atgatcctaa tccacttttc gataatttat taagaaataa aaggggggga ttgtcatgca
    11581 attaattcta aagattagta cgcatgattt cttagaactt gacgaattat gtgaatcagt
    11641 aaagaacgca acaaatgaaa aaatcacggt cactaattat attgaactga tgattcaaga
    11701 agaattaaag atgaaaaatg aaatagagag caatttcaaa tgttgctctc tagaaaaaaa
    11761 tgtgagggga taatcaatgg atgataaaca aaaaatgtac gaaaaaaatc gcaaacatag
    11821 tgaggcctta aattttcgtg tcgataaaaa gacttatctt gaactgacat tgattgcaaa
    11881 acaaagggga atttctagag cagacgtttg ccgtgagcgg ttaaagggac tcaaatatga
    11941 accgccgttg ttagctgaag atgatagggt agttttaacc aaacagttaa atcaaattgg
    12001 taacaatttg aatcaagcgg taaaggcatt aaatatcatt gctaaatatt ttagagaaga
    12061 atctgaagat aaaaaagaaa agagcctaca ttttagtttt gatgctagcc gttacaacat
    12121 ttttaaagat gaacttgcga atagcatagc aaaaaagttg atgattagtt atccagatga
    12181 catttttttg gagtccaatc ggagtgcccc ctcttttttt aaattatcag aagtagaaaa
    12241 agaatatttc gaatattgga tagaaaagca aactagaccg ggtacgaaag aagagtattc
    12301 ccaaaaagtt gatcggaatt taattcactc aattcagatt attgcaagtt taaaagatga
    12361 ggtgaaacaa ctttgggagc tactataaca tcgaaaggac gcaagaaaaa tttatcctcg
    12421 ctattacaat atgcagctaa tccttcaaaa aaagaaaaat gtgttgcagt ctcaggaata
    12481 aattgtagtg atgatagtga ggaagcactg caagaaatga atttagtacg taccaagatg
    12541 aataaatcta aagatatagc acaagcgttt catgttattc attcgtttga taagagtact
    12601 tctaaagagt taagtattga taaaatgcac gaaatagctg tcgaatttgc agagaaagct
    12661 tttccaaatt cgcaaatcat tgttgcaagt cacaatgata aagatcattt tcatagtcat
    12721 cttgtcatta ataatattaa catggaaaca tgtaaaaggt tgcgtattga ccctaaagat
    12781 ttagaactaa tgcgaaaaat taacgatcaa gtcctcaatg aacatggtct tgaatcagtg
    12841 aataatgagt actatgaaaa cttagaaaag agaaccaatc tttattcaaa cgatccttct
    12901 aagatgaaat atggaaaaat taattatcaa gagtttgtgc aaaatgcgat cgaagcaacg
    12961 ttggaaaaat gcgaagtgaa ttcttttgaa gatttttcgg atcatttggc aaaagaatat
    13021 aacattgaag tttatcaatt ttcaaaaaca aataacaaac ttggctatgt tctttacaaa
    13081 caaggtgtaa atttctatga gcgtagaggt gagttaatta ctttaggaag agataaacaa
    13141 tctagaaaag aaaaaagtca gtatgtcgaa cgtactttta gtgcaagaaa gttagggaaa
    13201 agatattcat ttgaatctgt ttctgaacaa cttgaaaaga atttagaaga atcacatata
    13261 aaaaattttt ttaatatgga aagagagcaa gttatgtcgc taattagtgg agtaaattac
    13321 aaaactggtg agttaaatgt accgtttgtg gaattagatt ccatcgcaca aaagcaattt
    13381 agcgaccgtg aaggcgatga aaaattcatt aaatatgatg acttcttgcg agaggtagac
    13441 aagcattttg taaatacaat gtctttagaa gatgatcaag aatacacgat taaacttcat
    13501 acggatgtga atcctcaaac tttacgtagt gcgaaaagta aaacaatttc tattaaaaag
    13561 actgatcaga aagagttatt tctaccggca aagggttttg aaaattgttc tcatacacct
    13621 tctgctaaac agattcacta tcaaatcagt cgcataatga atgacgatgt aaaaatgtat
    13681 cgtgctaaaa aggattatga attcacacaa caaatgattg aaaatcagca aaaaaggcaa
    13741 caaaattttg aaatggaatt ctgaatgggc ttgttagtgg actttccagt tttttgccta
    13801 tgaagagttg cttggaaaga agcagttttt aggacatacg ccagctaccc atctacttgc
    13861 cagtcaatcc gccccgctca cgctaggcta ctttctggca agtcagatgg cgggtaaatc
    13921 tctgagggag caagctccct acagactccc tcccaaaaaa agaaaggtgg aagaaaaaaa
    13981 tgaactatcc atattttaaa gtctcggctt cagaagaaac taaagaaata ttcaacaatt
    14041 tttacaacca aaacaaagga atttttggtt caaaggcaaa tatgtttcgt gttatggttt
    14101 caaatttacc agtgttagct agtccatcaa ataataaatt taatgatcct gaaagcatta
    14161 aatttgaaca aaaaatttca gaactagaat caatgataag taatgaagta attgaaaagc
    14221 tggatgacat tgatcaaaag ttatcgtatt ctctaaaaaa caaatacaaa acggaggaga
    14281 aaaaagatgt ttaaagttta cttcccgttt cagtggctcg ttaaaggaat tcttttagtg
    14341 ctactaggat tgattctttt tggaagttat ctaacaatta aagccagaca ttttccagaa
    14401 gaaaagccaa taaaaattgt aacaaaagat ttaaaaatag gtgaaactta tcaggcagat
    14461 ggggttgaac taacatttaa aaatattgaa gtgaccgaaa aaagaaatga atttgcacaa
    14521 catgatcgtg tattacaagt gacctataca cttataaatg atacagaaaa tccgatacgt
    14581 ccacaacaat ggtcgattga aaataaggat ggtgaagaac tttatgagta tgatatgata
    14641 ttggataatc cagagtatat tgaaagtggc aaagaagaaa cagtaaatta ctattatgaa
    14701 ttaccgattg aaaggcagga ctaccaaatc gtagtacgta gagagaatgg ttacatagtt
    14761 gggttgccat ttactttata agttttattt tgttagtagt ttttaaggta atatcagttt
    14821 tgtgattttt gaaaatggaa ctgggagaat ggctgaggaa aataaagttg ttccgtttga
    14881 aacattagtg ataaataagg aagagtttga gcaacttttt cttgattttt ttattcaata
    14941 tgacatgatt tatgatttta gttcgtcact agatttattt gaattagaag cagaaataat
    15001 agaaaacagt cgagagaaga atggtaaaat cattatttca gtagaaaaat tcaatgaatt
    15061 attctcacaa acatttgaaa tagatccaga ctattatcaa ccacaagaag tttttcgaga
    15121 gtttagaaat aagattattg gttttagtca aactacaaaa tgaaagctta ataaagcaag
    15181 tgttgataga attattcctc aacgcttgct ttattttatg ggcacttcat aatagaggta
    15241 tagagaagag aggtattcat tttggatact attactccaa caaacttcaa agaaaatata
    15301 ggtaaagtgt tgcaagaagt agttcattca aattctgaaa tagaaattac tagggattct
    15361 aaaaatggat tgaacgatgg cgtcattatg atttctaaga gaaaatggga gttgttacaa
    15421 gaagaacttt atttacaacg aacgggtaca tgggcttatg tatctgattt a
//
LOCUS       DACBZK010000062        15230 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.064, whole genome shotgun sequence.
ACCESSION   DACBZK010000062 DACBZK010000000
VERSION     DACBZK010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.064"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            278..787
                     /locus_tag="IVD66_002086"
     CDS             278..787
                     /locus_tag="IVD66_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP6146288.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="IVD66_002087"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="IVD66_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP6146289.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="IVD66_002088"
     CDS             2322..3302
                     /locus_tag="IVD66_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6146290.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="IVD66_002089"
     CDS             3424..4842
                     /locus_tag="IVD66_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HAP6146291.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="IVD66_002090"
     CDS             4913..6382
                     /locus_tag="IVD66_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6146292.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="IVD66_002091"
     CDS             6392..6859
                     /locus_tag="IVD66_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAP6146293.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /locus_tag="IVD66_002092"
     CDS             6895..7767
                     /locus_tag="IVD66_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP6146294.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7848..10382
                     /locus_tag="IVD66_002093"
                     /pseudo
     CDS             7848..10382
                     /locus_tag="IVD66_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            10538..11311
                     /locus_tag="IVD66_002094"
     CDS             10538..11311
                     /locus_tag="IVD66_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6146295.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11304..12095
                     /locus_tag="IVD66_002095"
     CDS             11304..12095
                     /locus_tag="IVD66_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP6146296.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12105..12596
                     /locus_tag="IVD66_002096"
     CDS             12105..12596
                     /locus_tag="IVD66_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6146297.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12614..13024
                     /locus_tag="IVD66_002097"
     CDS             12614..13024
                     /locus_tag="IVD66_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP6146298.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13028..14428
                     /locus_tag="IVD66_002098"
     CDS             13028..14428
                     /locus_tag="IVD66_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HAP6146299.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14451..14825
                     /locus_tag="IVD66_002099"
     CDS             14451..14825
                     /locus_tag="IVD66_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP6146300.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYDSLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5283 a         2136 c         3047 g         4764 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acctgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttacatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttc aattagtaat tgaagggacg cctaaaagtg aaaaaaaaaa
     7861 tgaaagatga agtattagag tatatcaaaa ataatttaaa gtattacgat ttttctgctc
     7921 aagatattgc aatgaaattt tgtattaaaa gaaatgtcgc ttcccactat ttgaatcagt
     7981 tattttcaga tggaaaatta ctaaagaatg attctgttag accagtaatg ttcaagtata
     8041 atcaacaaaa gccaaaagac tgcttttcta agtttattgg agcagacata tctttgaaat
     8101 ccactataga taaatgcaaa gctactgtaa tgtatccccc taatggcctc ccattaataa
     8161 taaaaggaaa cagtggcgtt ggaaaaagtt ttttagcaag tttgatctat cagtatgctc
     8221 ttgatagaaa agtaattcat aatgacgcaa aatttgttgt tgtgaattgt gcagattatg
     8281 caaataatcc agagctattg tcagcagttt tatttggata taaaaaagga gcctttactg
     8341 gggctgaaaa agatactgca gggatgctat cttctgctaa tggaggatac ctttttttag
     8401 atgaggttca caatctaagt gcagaaaacc aagagaaatt gtttcttctt atggattctc
     8461 aaaagtatcg taaacttggt gaaagtgtgc aatgggagta tgcaaatgtt cgccttatct
     8521 tagccacaac agaagataaa aatacctctt tgttagcaac ttttagaaga cgcatcccag
     8581 ctgaaatcac tctgccagat tacaataata gaagtacatc tgaaaaaatt caattattat
     8641 ttgaatttct taaagatgaa gcaattacga ttgattcaaa aatattttgt tcgattgaac
     8701 tttttactga tcttttatcg aaaacatttg aaggaaatgt tggagaattg aggaatgaaa
     8761 tcaagcttct ttgtgcagaa ggttatttag gaaataagag aaagtcttca atttatttag
     8821 gggacaaact agacagcggt ttttggatag atccagaaat tagtatagat ttaaaaaaat
     8881 gtttcttaaa tcactttctg aaattgattt gattgaactt tttcaaaatc acatttcaat
     8941 tgaagaaagc atgagtcaat taagagatag aatacttaaa gagtgtgcag gttcttctga
     9001 gtataattat ttagaaagtg acgaatttat agcattaaga aactatgttg ttaataaaat
     9061 atcaccaatt attgattcga caggtctatg tttattagat gaattcttgg cggatatcag
     9121 tctatttata atgtttattg atgtaattga agaaacatca agaaattttt tgctgtctaa
     9181 gttcagaaaa tttcgtatga aaaatgataa acaaaaatta ttggcaaatg agatttggag
     9241 tagtttagaa gtcgaagaaa gtaaacaaga acttttgttg aaatggatac tttttcttgt
     9301 aaagaagttc tatgtgaaaa taccagaaac ccattgtctg atagttatgc acggtaaaat
     9361 aacagcttct gcggatcgca agggaaacaa ataagttgct gaatacatat gtttatgagg
     9421 ctttcgatat gccaattgaa ggtgagacta gtgacttaat taacctaatc aacaattttt
     9481 gtaaaagtat agatacgacg aatggactca ttctgctagt tgatatggga tcattggaac
     9541 aaatgtatga aaaaattgaa tccaatgtaa taggtgattt ggtaatttta aacaatgttt
     9601 ctacagcttt agcgattgaa tgtgggattc aagtttgcca aaaaaagcca attagtcatt
     9661 tttaccagat ggattttgat tcgtttcaag ttaaagttca gtattataaa ggattatcac
     9721 aaaagaaaaa tgtaatagta tcttgtctct ctggtgaggg gatttctgaa aaagttaagg
     9781 atattttaaa acggtatctc gataatcaag tggagatttt gatttttgat tttaacgcat
     9841 taaagaaaat agcaaaggaa aaagatacta tgatttttaa gaatacaatt tgtgttcttt
     9901 caaccactga attttacatt caaggaatcg attgtttaaa tttagaaaat ctaattaatg
     9961 ggaatcaaac cttagaaaaa ttaaataagt atatggactc ggatagctgt gagttctgct
    10021 taaatgaatt agttaaactc tttactattg aaggcgctag tactaagctt cgctttttag
    10081 attccaaaaa agtattcaat gagatagaaa aagtactata tttgtatgaa aaatattacg
    10141 atgtcaaaat cccaagtttt ctgagaatta atctatttct acatctttct ggaatgattg
    10201 aacgaattat gattggtgat ggaataacaa atgaacattt gaaagaggga gcgcaactat
    10261 ttgatacttt tttaaatgta tcaaaagatt ttttttcaga aatcaaagat atttactgta
    10321 ttgaaatacc caaaggagag tatgagttaa tctatacaat ttttgagcag actattttct
    10381 aaatagcata ctagcgtcta aaaaaatgaa agggtgtcca aagtatattt agacgctcat
    10441 ttaattaata tttactgtat tttcccgctt tattggataa tgttagttgg cacagtaatt
    10501 gcttatataa aagtataaga agaaaggaga gaacaaaatg gcgttttggc aaacattttt
    10561 agttgtgttg tatggatttt tcattaactg ggataaggaa gggcccaaaa tcggaacctc
    10621 ccaacctgtc gttgcaggtt tcttgaccgg acttattatg ggagatattc aaactggact
    10681 ttatatcggt gggactttgc aattaatgac actaggtatt actagttttg gtggtgcatc
    10741 agtaccggat tatcaaacag cagcattgat cggtacttat ttagcaatct caactaacca
    10801 ggatgcttct ataggaataa ctttagcaat accggtagca atgttaattg tacaactaga
    10861 tgttctaaag tggtcaacaa acattttttt tcaacaaaag gcagaaaaat tcgcacaaaa
    10921 agaagattat caaaaattag agtggatgca atatttggca tcaattaata caagctttgt
    10981 atctggaatt cctgttttgt taactgtgat attaggccca acgttagtgg gaagtgcaat
    11041 caattatatt cctgaatggg ttaccggtgg tttaaaggta gcagggggac tattacctgc
    11101 tgttgggata ggaatgctac ttaaatattt acctacaaaa gattactttg cctatttgtt
    11161 agttggtttc gttttggcag tttatttcca aataccaatt ttagggattt cgttacttgg
    11221 cgctgcaatc gcactaatcg tatataaaaa tagatcaaat aatactcaag tagcaccagc
    11281 tgcaacagga ggttttgacg aagatgaata agaaactgac aaaaatcgac aaacaagtaa
    11341 ttttccggtg gattctcaat ggtgcaactt cattaaatta tgaaaaaatg gaagggttgg
    11401 gttatgcgta ttctatgctt ccttttatca aggacacata taaagatgat cctgaaggaa
    11461 tgaaacaatc cgttttagct cacttacaat tttttaacac tacgccgtat acagcgcctt
    11521 acattattgg tatgaatgtt ggaattgaaa aagaagaaaa aaataagtct ttggaagcag
    11581 taagtgctct gaaaacaggt ctaatgggtc ctttagcggg aattggagat agtgtatttg
    11641 tagttattcc atggactatt tttggagcaa ttgcagctaa tatggcattg gaaggtagtt
    11701 ttgttggaat tattttgtgg atactggcat caattttatt aaggattact gcttatcctt
    11761 tataccttgc tgggaaagaa tcgggtgcga gcctactaac tcaaattgaa acaaaattaa
    11821 agtctattac tgatgcagta tcaattttag ggttaatggt ggtcggtgca ctcattgcca
    11881 cagttgtaaa agtgaatgtt ggctttgaat ttaaacaagg cgacttaaca atgaccggaa
    11941 atgaaatctt tgatcaagtt atgcctggtt tattacctgc atgtgtagta gcaattgtgt
    12001 attatttgtt aggacgaaag gttaaaccag tttatgtaat tctattaatc ttagtagttt
    12061 ctattgcgtt aagagcgtta aatattttga agtaggtgtt gaatatggat gaaaaaatga
    12121 aaggtattat acatgttcgt attgatgatc gaatgattca tggacaagta gcaacacaat
    12181 ggacaaatca attgagtgct aacagaatta tggttattaa taatgaagta gccaatgatg
    12241 acgtaaaaaa agctgtagtt cgcctcgctg caccacctaa tgttagaact tcaataatta
    12301 caagggaagt agcagttaaa aatattcttt ctggtaaata tgaaggacaa aaagttctta
    12361 ttgttgcagt ttctccaatc gatgttaaat ttttgattga taacggttta ccaataacaa
    12421 gtgtaaacgt aggaaattta tcaagaagga atggaacaga acgcatccgt ccgacgataa
    12481 atattactga agaagagaga gaggctttta aagaactaat tagtgatgga gttgaagtga
    12541 cagtgataca aactcctaga gattcaaaag aatttttaaa ggattttatt tattaagaac
    12601 agaggatgag tggatggagt ttataattac atctcatgga aatattgcca ttggatttgt
    12661 agatacatta aaaatgtttt ttggcgataa tttaaattgt catgtggtaa cacttggaga
    12721 tgcaggcatt gaagaattcc gtgaaaacat tgaaaaaata gtttctcaag taaaaaatca
    12781 agaagttatg gtatttgctg acttgattgg tggaacacct ttcaacgaat ttgctaaaag
    12841 aagtgaagta tttcaaaatg ggtttcaact tcttggtggc atgaatttag gaattttgat
    12901 tgaggctgtc aatttgagat tacaaggaaa aaaaagcgat gatatcatcg aaaatctaag
    12961 aaatatgaat acaattgcgt gtcttgcaga tatgcaaaga catactaacg aagaggatga
    13021 gtgataaatg caaaaaattt tttacaagcc taaagatttt tggtttgggg attgcatgcc
    13081 tttttataaa gatggaactt tttatctatt tcatcaacga gatacgagaa atcctaaacc
    13141 tttaactgat ccttttgggt ggtcactagt tacaaccact gattttgtga aatttgaaga
    13201 atacggggaa gtaattcatc gtggtggcaa cgatgacatt gatcaataca tttacgctgg
    13261 aagtattgtc caaggaatca atgagtattt agctttgtat actggacata atcgcaaagc
    13321 taagttggat ggaaaaactt cagaagtgtt aatgattgca agttctaaag atttaattca
    13381 ttggaaaaag gatggcgaag cagcaaaact tgttcctcaa gaaggatatg ataagaatga
    13441 ttggcgcgat ccttttgcaa tttttgatca agatcatgga aaatacgttt tgatactagg
    13501 agctagaaaa ccagcaagta agaaaaagcc gacggggaga ttggtctatt ttgaatccga
    13561 agatttaaaa gattggaatt tcaaaggaga ctactgggct aataatgaat ttaacatgat
    13621 tgaaatgcct gatatatttg aaattgatgg aacgtggtat ttactttttt cagagtattg
    13681 tgaagataaa aagactaaat atcgagtcgg agcaggatta ttttcagatt ggaaatcacc
    13741 agtagacgaa gctttcgacg gaaaagccta ttatgcagca agaacagtcg gaactaatga
    13801 aactggccgt tttctaactg gctgggtggc aacaaaagaa ggggagaacg atcaaaataa
    13861 ctgggattgg ggcggtgcac ttgttccaca tcaaattatt caaaagacag acaaaactct
    13921 tggtgttaaa ctgcctgaaa aaataattga gaattttaaa gaaatcactc cattttcaag
    13981 ttttaagtta gagaaagaat ttggaaaaaa agaaagagta attgttccta aaatcgaaga
    14041 ttattttcta tttgaaacaa ctttgactat tacatcgtta acaaaggagt ttgctttaaa
    14101 attatttgta gatagtgata ctcaagaagg atacgaattt cgtatttcat tgattaataa
    14161 tcagcttact ttcggaaaaa ctccgaacta tccttggcct caaatgtttg ataaggggct
    14221 gcaacgacca ctatttttgg aaataggcaa agaatatgaa ctaaagttaa ttgttgatga
    14281 tacgatagct gttttatata ttgataatgt tgctttaagt actagaatgt atgataaagt
    14341 cggaacagca ttaagtatga ctgttacgga gggagcaatc aaggtagata aactagacta
    14401 ttcaataaat tatgaatgtg gattttaaaa caattgaagg gatgatgtaa gtgaaattaa
    14461 atggtttaca acatattgga attccaacaa aagattttgg agcttcaaaa atcttttatg
    14521 attccttagg gtttagtctg attaatgaag aaatgaatgt gggaagtaaa gtcggctttt
    14581 tcgagttgaa tggaacgata atagaaatat gggaagataa aactactgag tgtagaggag
    14641 ccattgatca tctagcatta gatacggatg acatagatga ggtattcaat tcaattcaag
    14701 atttaggata tgaattatta gataaaaata ttatggaatt accgttctgg gaaaatggaa
    14761 tccgttactt taatttctac ggaccaaatc atgagattat agagataagc caaatgaaga
    14821 aataaataga taacgaagtg ctctaagttg gtatgaacga aaagtacttc attttttggt
    14881 atcagcattt caatagttta atgagaattt actatttcaa attaattcaa agtgacagta
    14941 ttttttactt atttggtttc aaattttgta atccttccta tttattggaa tacactccac
    15001 attttgtata caagtcatat catgttttag caaagctctt accaagcaaa gttataatga
    15061 tgttttccaa agtttgatct ttcgatggag gctaacacat attttttgca ggacagccaa
    15121 aattagatgt atagaataga gtctgtgagg cgtatagaca gtttattgtc tgtatgcctt
    15181 tttttatttt gaaaaatttt tagtattttt cgaaaaatgc tcactcctag
//
LOCUS       DACBZK010000063        15140 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.065, whole genome shotgun sequence.
ACCESSION   DACBZK010000063 DACBZK010000000
VERSION     DACBZK010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15140
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.065"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..344
                     /locus_tag="IVD66_002100"
     CDS             <1..344
                     /locus_tag="IVD66_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146301.1"
                     /translation="NIKTSTKLICKLFKLDKISNIDDVKSKILTRKVSEPVKLTAQDK
                     KNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSGEKVTFKINFITAISKLEYGKQKK
                     RDNNDQYLPKK"
     gene            425..1045
                     /locus_tag="IVD66_002101"
     CDS             425..1045
                     /locus_tag="IVD66_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146302.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            1746..2030
                     /locus_tag="IVD66_002102"
     CDS             1746..2030
                     /locus_tag="IVD66_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6146303.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            2033..2950
                     /locus_tag="IVD66_002103"
     CDS             2033..2950
                     /locus_tag="IVD66_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6146304.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            2943..3725
                     /locus_tag="IVD66_002104"
     CDS             2943..3725
                     /locus_tag="IVD66_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP6146305.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            3726..4406
                     /locus_tag="IVD66_002105"
     CDS             3726..4406
                     /locus_tag="IVD66_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6146306.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            4399..5295
                     /locus_tag="IVD66_002106"
     CDS             4399..5295
                     /locus_tag="IVD66_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP6146307.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            5490..7139
                     /locus_tag="IVD66_002107"
     CDS             5490..7139
                     /locus_tag="IVD66_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAP6146308.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            7733..8668
                     /locus_tag="IVD66_002108"
     CDS             7733..8668
                     /locus_tag="IVD66_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6146309.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            8661..9431
                     /locus_tag="IVD66_002109"
     CDS             8661..9431
                     /locus_tag="IVD66_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6146310.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            9847..10830
                     /locus_tag="IVD66_002110"
     CDS             9847..10830
                     /locus_tag="IVD66_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HAP6146311.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            11277..12311
                     /locus_tag="IVD66_002111"
     CDS             11277..12311
                     /locus_tag="IVD66_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP6146312.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTRAGS
                     NQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKILV
                     INGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELGI
                     DQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMFA
                     KTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHMLG
                     KVVVSGPFNG"
     gene            complement(12400..12723)
                     /locus_tag="IVD66_002112"
     CDS             complement(12400..12723)
                     /locus_tag="IVD66_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAP6146313.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(12710..13417)
                     /locus_tag="IVD66_002113"
     CDS             complement(12710..13417)
                     /locus_tag="IVD66_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HAP6146314.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            13503..13844
                     /locus_tag="IVD66_002114"
     CDS             13503..13844
                     /locus_tag="IVD66_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HAP6146315.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(14015..14863)
                     /locus_tag="IVD66_002115"
     CDS             complement(14015..14863)
                     /locus_tag="IVD66_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146316.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
BASE COUNT         4853 a         2579 c         3200 g         4508 t
ORIGIN      
        1 caaatataaa aactagtacg aaattaattt gtaaattatt taagcttgat aaaataagca
       61 atatcgatga tgtaaagtcc aagatattaa caagaaaagt aagcgaacca gtaaagctaa
      121 cggcacaaga taaaaaaaat ggaattgttc tttatggtga tgatgcaaag tataactata
      181 attgggatac ctcctcagaa gctgaggtat taagtattcc tactaccgat acttcagggg
      241 aaaaagtcac ctttaaaata aattttataa cggcaatttc taagttggag tatgggaagc
      301 aaaaaaagag agataacaat gatcaatatc tacctaaaaa ataacgaatt aatgatgcat
      361 atgttaaagt tgtttttttg aattaaacaa ctcaatttat tcagttatat gttcatcgca
      421 gcaagtgaac attaatcgag ttataaaatt aataggagct aaaaatataa ataaagttcg
      481 atcagaattt atttttccag aagatttttt taactggttt ttttatcaat tcagtgaatg
      541 caagcgactc ttaggtgaga attattactt aaaaggaatc ggcggattta tggggaatgt
      601 ggctgatgaa caaaatatta taaaaggaat atctgaacaa acatcagagc ttacagtaac
      661 taaagcattt ataagtaatg gtgaaagttt gaaaaatgta actgcgcgaa ttagaaaaga
      721 aaatgaagta gacattgttt ttggaattga ccatgaatgt aattcagtga tatatgtaac
      781 acaatcagca aatttaattc tttttgagaa tggttgcaag gacgatttta tggtggtcta
      841 tttgtacgat atactaattc caaaacttcg ttccttatat atgtcttctg aaagtatttt
      901 tgtgagtgaa caaaagggat ctttctcgaa aaaaataggt attgaagtaa ttgaatcgat
      961 tatgtgtcat aatcatatta cgctagaaga attagaaatt ttgatagggc aaaaaaataa
     1021 taacacgaaa atacaagttt cttagaaatc attttttatt gagatatcta gataaatgat
     1081 ttattcttca atcaaccaac tcgccaagct gaggtaatgt tttgaggtaa tgataacata
     1141 caacttttta taccctagta aaactctata aacaaagact tattaatttc gcatgaaata
     1201 cattcctgta aaatgcaata aaatagagtt ttgtttaacc aggtcttaag aaagcccgta
     1261 aagcttcaca gttctcaaaa cgttaattgc gattatcgtt cgagttcacg agttacgaga
     1321 atcgtactgg gcgaagcaat gctgagcgca gttaccttaa tcctaacttt tctggcactt
     1381 tccacaattt ggaaagtgcc ttttttgtgt ttttagctat gttaataggt aggattcttg
     1441 gtctataata tcattcgatc tataaacaaa cgggaaaaag ataaagtatc atcaaacaat
     1501 attatttatc cgcttctgag gttgtgacag aagtggtcag cttcaagaaa taagaaggaa
     1561 tttacaaaaa ttgcttctca tgtttgataa atattgtgac ttgtgaccga ggagttggca
     1621 ggagaacacc gtttattcgg aagaagggat tgtgaaaagt cttttgtcat aacctcttat
     1681 ttggtagcta attgtaaatc ccaaacggca tgtattattt ttcataagtc cgtttttaag
     1741 gattaatgtt ttcttttgct ttttatatgg tctggcttca gcgagaagtt ccaacgcata
     1801 tacaaggacg tctgatgtca acgataacaa cgattaccat ggtggccagt ccacttggat
     1861 tagcactgtt tggtgcgctc tttgattggc agacaactca accacgtctg cgagacagtc
     1921 tgatttttct tgaaattcaa ttggaaaatt tacactttct ttatacattt ctggctgctt
     1981 tctttatacc cgtcaactat acttcactta tcaataagaa agaaggataa gtatggattt
     2041 tggaaatgaa acggtcttga aagcaactgg tataaccaaa aaatacggtg ctgccaaagc
     2101 attagataaa gtatcgatcg aaatcaaacg tggaatgatc tatggtttga ttggggagaa
     2161 tggagcgggt aagtctacct ttatgagaac tattatgggt ttgatctcga ttgatgaagg
     2221 ttcgatcgaa ttatttggaa cgacggattt gcaggcagca agacgacgta tgggtcaatc
     2281 gattgaaacc cctgctcttt atccagaatt aactgcaaga gataacctac gtatccaagc
     2341 agcgaacggc ggtgtgtcgg atagagaaat cgaagacctg ctgaaaatga tgcgattgga
     2401 aaatacaggg aaaaagaaag caaagaattt ctctttaggt atgcgccagc gtttagctat
     2461 tgcaaatgca ctgatcacga atccagaatt tttgattttg gatgaaccga cgaatgggat
     2521 ggatccagca gggatggcag aaatgcgaga aatcatccaa cgtttggtaa aagaacgggg
     2581 catcaccgtc ttgctttcta gccacttgct agatgaattg tcacagatcg ccactcacta
     2641 cggtattttg catgaaggac acttgatcaa agaattatcg aaagaagaat tggcacaaga
     2701 atctcgtcaa tttataaaaa ttgacacttc ggcgacggaa caagcagtaa cggttctcga
     2761 ctctcttggt tatagggatt attttgtcca atctagccgt gttatccagc tttttgaagg
     2821 aattgaccaa gtagcagcca tcaatcaagc attggtagag gcaaaagttc ctgtggatgg
     2881 tatccaccta gttgggcaaa aactggaaga ttatttctta caattaactg gaggcaatcc
     2941 acatgtttaa tctattaact gctgaaaaaa taaaagtatg gaagagccgt aaaatgtggg
     3001 tctcactagg actgatggtc gtacttccgc ttttttattc ttggaacgaa tggtatatgc
     3061 atacaaaata cggcaatgaa ttaaaccaag caacggatac agtcatcaac ggtgcaacag
     3121 ggattttaat ggtggaaaaa atggctgcat ggattcttct ggctttcgca gcatttgcgt
     3181 gcttttatat tggggaagaa tttcaaaacg gtacgattcg caatacgtta tctttaggac
     3241 ggaatcgaat gacttattat gtgtcgaaac ttctcgttac gcttttgatc acaacacttg
     3301 gcgtggtttt gattacgggg ctagccatga ttgcttacac acttgctttc ggatttggtg
     3361 aagttgaggg aatcaaaaac tatggaaatt atgttctaaa agtatttcct gtattgcttc
     3421 tgctgatatt agcgacatta tctgttccag tggctttgac attcatcact agaagtacca
     3481 gtgtcagttt gcttctttct tttctttata tcatgggaac ggccttcgtt cccggtgttt
     3541 tcgcaaaaat caaaggcttg gaatttctaa cggagtggtt tacggaaacg tggctcatgt
     3601 atacggactt tgcgcaacaa gcaacttatt cgcaagcacc gaaaatgatt ctggtcagtc
     3661 tagtaacaat cgtggtatca tcagctctag gaatgtttat tttccaaaaa tctgacatta
     3721 agtaggtgtt cctgctggaa actattttga ttatcgaaga cgatgaagct gttcattctt
     3781 tactggagga ggttcttgaa cagagataca aacttcttga tgcttattca ggtacggaag
     3841 gaaaattatt gttaagcaca tatcctgtcg atttgatcct tctagatctc atgcttccag
     3901 ggctttcagg tgaagcattg ttagcagaaa tccgacagac atcgaatgtt ccgatcatcg
     3961 ttctttcagc aaaaagcgat caaagagata aagtttcctt gttggcagca ggagcggatg
     4021 actatgtgac gaaaccattt gatatcgaag aactgttgtt acgaatcggc atccaacttc
     4081 gtcatcagac ttctgtccaa gtaaaagatc tgtcgcaacg catctattac aaggaaatct
     4141 tactggacaa agagtcgagg gatgtaaatg tgaatggtgt ggctgtccat ttgacaggaa
     4201 gagaattcga tctgctgaag ctttttttag aacatccgaa aaaagtattt tcgcgagcaa
     4261 atctttatga aacagtttgg caagaaccat attttgatag tgagaaaaca gtgaatatgc
     4321 atatttccaa tcttcgaggg aaactagcaa aggcacatgc tgtgtatatt catacggtgt
     4381 ggggagtggg gtttagattt gattaagtgg ctgttgcttc tcgttgttat ctttatggga
     4441 agttttattt tcttcctgca aagggaaatc aagagattaa ctaagaaaat cgccactctt
     4501 tctgaacgac aagaatatgg tggtcgtctt tcagtcgaat ttcgagaaaa gaatctaatg
     4561 gacctagtag atgcactgaa tacatgggtg gatgaaaatg aacaaaaagg acaagcattt
     4621 caagaaatgg aagaaaacat cagactatcg atcgtcggcc tttctcatga tctcagaact
     4681 cctttgactg ctattaacgg ttatgtacaa ttactggaac aggtagagga tacggagaaa
     4741 cgggagaagt atttaacgat catcaaacaa tctgttgcaa gattactcag tatgacggat
     4801 cagttttatg atcttgctcg aatagagacg aagcaaaaag aaatggatct ccatacgctt
     4861 tctttttcta aagaggtgga agaagtattt ttctcttttt atgaacaatt ttctgagaaa
     4921 aatatcgagg tagcgttcgc tgaacactcg ataaatacaa ctgtattagc agatccgctc
     4981 atgttgctgc gagtgctgca aaatatcata cagaatttat tgcgttatgc agatggacaa
     5041 gcaaaggtga cattttcaaa agaggattca ttcattcgat taacagtggc caatcctatc
     5101 aaaccaggag cgcaaacctc tgttgaaaaa gtcttccagc gtttttatac cgaaaatacc
     5161 agccgcacaa atacggaatc tagcggaatc gggctttacc tgtcaaaaaa attggtggaa
     5221 ggaatgggag gagagatgac cgctagatta gacgggggca tcttctccat ctccgtcaag
     5281 ttgcggaggg tttaattggc tctaatttac ctgaagtgaa tgacaaaaaa ttgtatctcg
     5341 ttttaaagac atcttctttt ttggaaggtg tttttatttt ggtgtgattg atacgaatta
     5401 ggtaacgaag acagttattt ttgtaccccc ttttcaaata gcgcaacagt gctatactaa
     5461 aactaacaaa tcaaggaacg gagagggata tgggccaaag agaatttatc gttttaatta
     5521 ttattgcagt tgttatttta ttagttgttt tagacatttt ttcacgtttg aaagtaaagg
     5581 aaacagttcg tagtaattgg ggaaaaattc cttatcaacc gagatttgat aaagaagaaa
     5641 gtttgaagga tgcgtggctc acggagaaaa aattccgttc atgggatagt gaaatcgacg
     5701 atcttacttg gtatgacttg gatatgttcg aagtatttga agggatcaac agtacctatt
     5761 ctagtgtagg ttcagaagcg ttgtatcagc gtttacgtag ctttgatttt ggagaagatt
     5821 atcagttaga aaaactaatt gctttttatc aggaaaatcc tcaactgaga gaaagaatcc
     5881 aatatcaatt cgctcgttta ggaaaaaaag atcataattt tgcaaaacaa tatctagcgg
     5941 atggaaaaag taaaaagatt ggacgcgtag gtttatttat ttttcttggc ttgcttccgc
     6001 tggtgggtgt aggtttgctt cttttagggc aagtactagg aatctatcta gcaatcggtg
     6061 gcttagtatt caatacggtc tattatctag tgaagaaaca aacactagaa acagagctga
     6121 atagcatgag ttatttggtt tcaacgattt cagccgccaa tcagttagca aaaatgacga
     6181 caccacttca aaaagagctg aaacagcaaa ctaaaccatt aagagacatc cctaaattag
     6241 gtttttcatt tcgaatgaag agcgggagtg aagcagaatt gatttttgaa tatgtcaaca
     6301 tcatgttcat gctgccattt atctcctatc atttcgttct cactaaatta gaaaagcatt
     6361 caactgaagc catcaagctg tgggaattgc tgggagaatt ggaagttgca gcagccgttt
     6421 tgaattatcg cacctatatg ccgatcactt gccgaccaga gtttactgag ggcggtgtga
     6481 cagcgaaaga tatctatcat ccattgttaa aagaagcggt agttaatcca gtcaactggc
     6541 agaagaatac attagtcacg ggttccaatg catcaggaaa atctacgtat gtcaaaagta
     6601 tagccatcag ctgtattcta gcacagacga tccaaacagc gattgcagaa cagtttaccc
     6661 tgcaacctgg acatgtgttg acttccatgg caatcgaaga tgatttattt gaaggcgaca
     6721 gttattttgt ttcagaaatc aaatcgatca aacgtttgct ggaccaagtg gcttccaaag
     6781 aacgctgcta ctgcttcgta gatgagattt taaaaggaac aaatacgatc gaacggattg
     6841 cttcttccgc ttcagtcgtt cggtggcttg cggagtatcc atctttagca tttgtcgcca
     6901 cacatgatat cgaattgaca gagattttaa agaattattg tgagaatgtc cactttgaag
     6961 aacaagtaac agaaggaaaa ggaatcagtt ttgatttcaa attaaaagaa ggaccttcaa
     7021 ggacccgaaa tgcgattgcc ttgctgaaag ttttgaatta tcctaaatcc atagttgaac
     7081 aggcccaaaa agaaagtttg ttgttcgatg aacagcgtca gtggtatccg tttgattaac
     7141 tttatcaaac gaagcatgat gcgtgggtcc aaaaagacga ttatcaaaag aagtacattg
     7201 atgccaaaaa agtggcagaa ttcaatggga acgagtctgc tgtccagatg atcttggaag
     7261 atttagcaaa agacgataca aaataaacca cgctgtcttc cttctagcag cttttatcga
     7321 aaaaacttag catcagcgac gagacgcacg ttccatggca aagttctccg taaaacaaac
     7381 agcgaaaaca gaaattgaaa ataactattt ccattttatt tatttcggtt aaaataaaag
     7441 aaaaaagctt tcgataaaag gacggaggaa agcttaacat gaataaaaaa gacaagaacc
     7501 tcagttataa ggatcttcta tatgtcatcg tagtagttgc tgtcggtact tttatgattt
     7561 taaaagttcc agagttgttt agatagttat tctatcgaag atgatcatga actagaaaac
     7621 acatctcctc tttgttagca ggtgtgtttt tgtgtggaag ccaagttgtt ttttcatctg
     7681 ctgtattcca tgatacaatt aagaatcatg tctataagga gataggaaat aaatggcaaa
     7741 tgcgcttgaa ataaataatt tgaaaaagat ctatggaagt ggggtcgaag cattgcgggg
     7801 aatcgatctt tcggtgaaag aaggagattt ctatgcgcta ttagggccaa atggagctgg
     7861 gaagtctaca acgatcggga ttattacttc tttagtcaat aaaacatctg gaaaagtgaa
     7921 tgtcttcggt tatgatctgg acaaggatct agttcgagca aagcaacaga ttggattggt
     7981 tccacaagag ttcaatttta acccttttga aacggtccag caaatcgtcg tgaatcaagc
     8041 aggctactac ggtgtctctc gcaaagaagc gatgaaacgc agcgaaaaat atttgaagca
     8101 gtccaatctt tgggaaaaga gaaatgtccg tgcacgtatg ctttccgggg gaatgaagcg
     8161 aagactgatg attgctaggg cattgatgca tgaaccacgt ttgctgatct tggatgaacc
     8221 aacagcagga gttgacatcg agttgagacg cgagatgtgg gagtttctac gagaattgaa
     8281 cgaaaatggt acaacgatca ttttgacgac gcattatcta gaagaagctg aaatgctttg
     8341 tcgcaacatc ggaatcatcc aatcgggtga actgatcgag aatacaagta tgaaagagct
     8401 tctgtcaaaa ctgcaatttg aaacatttat ctttgattta gcgccatatg ataccaaacc
     8461 tgtgattgaa ggatatgctt gtacatttga agatgagcag acaatcgctg tcgaagttga
     8521 acgaaatcaa ggggtgaacg gaatcttcga tcagcttaca agacaaggaa tcaaagttct
     8581 ttctatgagg aataagtcga atcgtttaga agaactgttc ttgaaaatca cagaagaaaa
     8641 taatcatacg gaggagaaaa atgtttaatc tttattttac tgcattaaaa agtttagcta
     8701 tcaaggaaac gaaccgctat ttgcgtatat gggtccaaac actggttccg ccagtgatca
     8761 cgacatcctt gtattttgtt attttcggaa aaatgatcgg tgggcggatc ggtgacatgg
     8821 gtggtttttc atatatggaa ttcatcgttc ctggtttgat tatgatgtct gctatcacta
     8881 gttcgtatgc caatgtttct tcgtccttct tctctcaaaa atttcagaaa aatatcgaag
     8941 aaatcttggt agcacctgtt cctacgcatg tgattatttg gggctttgtg attggtggtg
     9001 tgggtcgcag tattctcgtc ggctctctcg taacgatcat ttccttgttc tttgtaccac
     9061 ttcatgtgta ttcatggttc atggtcatca ttacattatt gatgacggca atcttgtttt
     9121 cattagcagg actgctcaac gggatttttg ctcagtctta tgatgatgta tcgatcgtgc
     9181 ctacatttgt cttgcagccg ttaacttatc taggtggcgt tttctatgcc atctctatgt
     9241 taccgccctt ttggcaagct gtttcaaaag tcaatccgat cgtttatatg atctccggtt
     9301 tccgttacgg attccttgga acgatcgatg tgccagtagc aacatcgatg atcgtacttg
     9361 tgttattcat cgttgttttg tacgccgtta cttggtattt gatcaataaa ggaagaggat
     9421 tgagaagtta gaaaagaggt tgtgaaatca gcgttttgac ctgagtatta gagaaacaaa
     9481 cgggaaaata gttcctcata ttttgttgtt ttttgagcga ataccgaggg tcagctgatt
     9541 gaacaccgtt tagtggagag gttgtgaaaa agctgttctg catcaagtaa taagaacagc
     9601 caaacaaaaa tagctcctcc tatttttcgt ttggttggac ttattaccgc agatgcaagc
     9661 ttttgaacac catttattcc ggaaaatgga ctgtgataag atttttgtca cagtcttttt
     9721 tttgctcaat cagaaacatc ttttaagctg ttcactttgc ttcttttttt gtttcctagt
     9781 ataatgacaa tgtttttgag aaagattgcg acttcactgc ttgatagaat ggagagtaac
     9841 aaataaatga ctactaattt ttggaaagag ctgccaaagc ctttttttgt tttagcacca
     9901 atggaagatg taacagatgt tgtatttcgc catgtcgtaa agcatgcagc agcaccggat
     9961 gtcttcttta ctgagtttac aaactcagac agtttctgtc atccagatgg aaaagacagt
    10021 gtacgaggaa gattaacatt tacagaagat gaacagccga tggttgccca tatttgggga
    10081 gacaagccag aattttttag agaaatgagc attgctatgg cagaaatggg cttccaagga
    10141 atcgatatca acatgggctg cccagtccct aatgtagcag aacgtggaaa aggcagtggc
    10201 ttgatccttc gtccagaagt agcggcacaa ttgattgaag cagctaaagc tggcggtttg
    10261 cctgtcagcg tcaagacgcg tatcggctat acggaaatgt ctgagatgga agaatggatc
    10321 agtcacctac ttcatcaaga tatagccaat ctttctgtcc atttgcgtac gcgtaaagag
    10381 atgagtaaag tagatgcaca ttgggaagtc attcctaaaa tcattgcttt acgtgaccaa
    10441 atcgctccac aaacactaat cacgatcaat ggagatatcc ccgatcgcca gacaggagaa
    10501 gaattggccg agaaatatgg cgttgatggc atcatgattg gccgagggat tttcaagaat
    10561 ccttatgcat ttgaaaaaga cccgagggaa catacagaaa aagaactgat cggactactt
    10621 cgtctgcaac tagatctgca agatcattat tcagaaatca tcccgcgttc catcacagga
    10681 ctacatcgtt tctttaaaat ctatatcaaa ggatttccag gagcaaatga cttgcgagtt
    10741 cagttgatga atacgaaatc tactgatgaa gtacgagaga tcttagagac ctttgaaaaa
    10801 gaacatccaa cgcttttcag tgaacaatga tttcttgctt gaacaccgtg aattagaggt
    10861 cgtgaaaaag ctgtcctgta tcaagtaata agaacagcca aacaaaaata gctcttcata
    10921 ttttgtcgtt ttttgagcta ataccgaggg tcagttgatt gaacaccgtt tatatcagag
    10981 gttgtgagcc tgccgtttaa ctctgagtca caaggagcaa tttcaaaaaa cagcttctca
    11041 tgtttgatga atattttgac ttgtgaccga agagttggta ggagaacacc gtttataaga
    11101 ggttgtgaca aaagtcttgt cgcaacctct tttttaacca aaaaagtgca aatagtttac
    11161 tttaagtaag agaataatta tgatgaataa aaaaggtgga acaaatagca tactatatat
    11221 attgaaatga acactgtatg gatgctccaa cttgatgaag ctaaggagga attcgtatgt
    11281 cagaaaagga attaatgaag gtagtcggtt tttatgaagg gttgccgatc gatgatccaa
    11341 aaagctttat tgatgaaaaa gaacagatac ctgtacccag ttcacgggat cttctggtaa
    11401 aagtcaacgc agtatctgtt aatcctgtcg atacgaaact tcgccaagat aacgggataa
    11461 gaaatgcttt acgtatctta ggttttgatg gagtcgggaa agttgttgct gtaggtgacg
    11521 aagtgcaaaa attttctgtc ggcgatcgcg ttttttacgc aggtacaaca agagcaggaa
    11581 gcaatcaaga ataccaacta gttgacgaac gtattgtcgc tcttgcacca aaaaatcttt
    11641 cagatgaaga agctgcagcc ttgccgttga cctcattgac cgcttatgaa ttgttatttg
    11701 aaaaatttgg tctaactcca gaagaaaatg ccaatcgcgg gaaaaaaatc ttagtgatca
    11761 acggatccgg gggcgtcggt tcgattttga atcaactagc gcattgggct ggcctagaag
    11821 tctacgcgac tgcaagtccg aagaattttg aatggctgaa aaaaacaggt gtagactatc
    11881 caatcgatta tcatcacgac ttaagtaaaa gttttcgtga attaggaatc gatcaagtag
    11941 agtatgtcgc tgtattattc gatattaccc gctactttga tcaaatcaag caccttgtcc
    12001 gaccatttgg acatgtggga acgatcgtag ggatcaaaga gccgttagat ataggtgttt
    12061 ggaaaaacca atctatcagc ttcgactggg agtatatgtt cgctaaaaca gactataact
    12121 atgaaatcga aacgcaagga gaagctttag cgcacattgc tgctttagca aatgaaggga
    12181 ttatccgcag tacattgagc aaggtctatt cagatgggat gaatgcgaag aacttgaaac
    12241 aagcaaccaa agacgtagaa acaggacata tgttaggaaa agtcgttgtt agtggtccgt
    12301 tcaacggata agcaagaata cgccgatttt tttcttattt gactttgata aaaacaagag
    12361 cgcatgacag taatttgcca taagctcttg tttttttatt tataataagc gaatcaacga
    12421 aagggaaaga attcctgcca agacgatcac caataagctt tttgaaagaa tagcagctaa
    12481 aagtgtagga actgaagcca aagcattttc gagattgatc tgcggcagat gtccgatatt
    12541 ttgggtaaat agactgctga accataaagc agacataatg acgatcggga caaaacttaa
    12601 atactcaagc aacggttgcg gtaaatcgaa ttttttcagt aagacaaatg gtaggaccct
    12661 agaaagccaa gttgctaaag tacaacctaa aatagtcagc aatgtaaact caaaagaagg
    12721 catgtttgat ccacaccccc aatccgcacc caatcagtgt tacaactaca atcactaagt
    12781 tgcttgggat aaaaatcagt ccgacatata ccagaatcaa agtgagacca atcaggatca
    12841 actgtaatcg tttagaggtg tttctatcag aaatgacttg aagataaagt aacccgataa
    12901 acatagcgac gatggcgaaa tccaaaccaa actttttcgg atcagtaata aaattcccta
    12961 aaagtgcgcc aacaagagaa gaacccaccc acgtcaaata agaaatccaa ttagctgtat
    13021 tcatccaacg aaagtttaac ttttgtccag tatagttcaa tttattcatt cccagtgcga
    13081 aactttcatc tgtcagcaat gtgccaatca gcagattttg aagcagccga tttttcttga
    13141 aataaggagc aatcgtcata ctcatcagaa tcattcggga attgactaga aaggtcgaga
    13201 aaacgatgga aagcaatggg ctgtgactag caagcatgct gactgtgata aattgggcag
    13261 aaccagcata gaccagcagg gacatcaacg tgacgactag tggatgaaat ccggcagctt
    13321 tcccaacgat accaaatgca agtccaatac cgatataacc gaaaacggta ggtaacgtgt
    13381 ctttgatcgc agtttttata tctaactttt catccaataa caaaactcct ttagcacgac
    13441 ataaattttc ataattgtcg ttaaacttgt gaatattcta aatttttaat gagcatttgt
    13501 caatggtggg attgaaacgt aaagaactag cgggtcgcag atttacacgt attgtttcgg
    13561 tgggaggagg cgcgaaaaat cttgcatggc tacaaatcca agctgatatt ttcgatgcaa
    13621 cggtctattg tttaagtgtg gaggaaggac ctgcattagg cgcaacaatg attgctgcac
    13681 tagggttagg gtggttcgac acacctgaaa gttgttgtca gaattttatc caatatacag
    13741 atgcagtgga acctctctta caaaatgtag aaaagtatca taaaatctat caacaatgcc
    13801 ggaaaatcta tccagcaacg aaggaaattt gtcatgactt ataaaacaaa acgcgtacct
    13861 aatagtcaaa tgactaatat tgggtacgcg ttaagtcttc tttacttcat cctttgcatg
    13921 attcgtgttt ttaaagcaag gtctgctgta tttcttgtgg atttaggatg gttgttatcg
    13981 tttacttgct atttttcatt gaaatcgtct ttctttaccg tttctttagt tttttatcta
    14041 tttttttctt ttggttagaa aattcttttt cccgaaagtc ttctttcagg atttttatag
    14101 agtagcgttt tgaataagag gcgtcagtat gatcgacttg gcagacgaac caagagaaca
    14161 tttgcctttt ttctgcatga ggtgcttctg ctaataattc tttccataaa taataacagt
    14221 cctctatcag aagaagggtt cgttcatcct caggctccca atagaatgtt tcgagagtag
    14281 caatcacttc attgatcaat tcgaatgcgg gaagataggc attttgctga ataagcgatt
    14341 caactgcttc ttggatgaac tttcgcatct ccatgatgaa cttcgctgtt ttcctgtttt
    14401 tgtttttctt gataatatga tcgtatttat ggatgatagt tgttaattta tctgaataat
    14461 ttattgcatg aaatggcatc ttaactttga agcgttcgat aaagtgcgga tgttctataa
    14521 gaatctctgt taaaagctcc cgtacaagag aggaactagc ggaggaaaca agggacgaga
    14581 gttcggaaag tgagtagttg gattttttta ttggacgttc ttcgtaagcg aataagacag
    14641 cagccatgtg tttgcatttt tttccttcta tggcatatag acaatcacaa gtcatgttgg
    14701 tcttttcatc ccaagtgatc actaccttat aatcttccgt gccagaaact gttgcggaca
    14761 agtacttgct tgtatagttc aaatgacgga caaaaccgtg cagatgatag ctgtaaccgc
    14821 gttccaaaac gttttcagga aaatactcaa gccaattatt catctagttc tcctttcatg
    14881 aaacacttat ttatatttag tataaagaaa cgtttaagaa aaaagtagct gattttacat
    14941 atttgataat cacttttgct cgaattgtca aaaattcatt ctccttttct tttcttagag
    15001 aatgtgagaa aaagtaaaag aatagcgtgt tttaaagatg gaactttttt tgttttttat
    15061 ttatctgaca aaaatgaagt gattttgtta gaaataaata attgttccaa ttgataaaag
    15121 aggtatgatg tatcgcaaag
//
LOCUS       DACBZK010000064        14839 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.066, whole genome shotgun sequence.
ACCESSION   DACBZK010000064 DACBZK010000000
VERSION     DACBZK010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14839
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.066"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            417..1031
                     /locus_tag="IVD66_002116"
     CDS             417..1031
                     /locus_tag="IVD66_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP6146317.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            1804..3543
                     /gene="yfcC"
                     /locus_tag="IVD66_002117"
     CDS             1804..3543
                     /gene="yfcC"
                     /locus_tag="IVD66_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAP6146318.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            3700..4884
                     /gene="iadA"
                     /locus_tag="IVD66_002118"
     CDS             3700..4884
                     /gene="iadA"
                     /locus_tag="IVD66_002118"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAP6146319.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            4995..5198
                     /locus_tag="IVD66_002119"
     CDS             4995..5198
                     /locus_tag="IVD66_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAP6146320.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(5299..5961)
                     /locus_tag="IVD66_002120"
     CDS             complement(5299..5961)
                     /locus_tag="IVD66_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6146321.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(5974..7476)
                     /locus_tag="IVD66_002121"
                     /pseudo
     CDS             complement(5974..7476)
                     /locus_tag="IVD66_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724022.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            8024..9703
                     /locus_tag="IVD66_002122"
     CDS             8024..9703
                     /locus_tag="IVD66_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAP6146322.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            9830..10309
                     /locus_tag="IVD66_002123"
     CDS             9830..10309
                     /locus_tag="IVD66_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HAP6146323.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            10528..11208
                     /locus_tag="IVD66_002124"
     CDS             10528..11208
                     /locus_tag="IVD66_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAP6146324.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            11216..12547
                     /locus_tag="IVD66_002125"
     CDS             11216..12547
                     /locus_tag="IVD66_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP6146325.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            12562..13524
                     /locus_tag="IVD66_002126"
     CDS             12562..13524
                     /locus_tag="IVD66_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HAP6146326.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            13635..13973
                     /locus_tag="IVD66_002127"
     CDS             13635..13973
                     /locus_tag="IVD66_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HAP6146327.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            14052..14759
                     /locus_tag="IVD66_002128"
     CDS             14052..14759
                     /locus_tag="IVD66_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HAP6146328.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
BASE COUNT         4763 a         2579 c         3191 g         4306 t
ORIGIN      
        1 ttttttgtat tttcttgctt gcacttggat aagagattac ttacaataaa ttcagataga
       61 aacagctgaa taaaaaaagg ctccctgacc cttagttggc gctaagaatc agggaatgac
      121 cagtcacaca catacaccct gaccgatcat tttgccatag tcaatgcagt gcatcgacct
      181 aatttattgt acctaatcta gggtgaaaat tctaccccta tgtagatatt ttccatggtc
      241 tgcacgttgt tttatttgct atgtcaaggt attgggcgta ttcgttcaat gccttttttg
      301 tgtttgaaac agcaaagacc acatgtgtta ctgtctaact actgtttttt tatgtacttc
      361 cttagattag gcagctgttt ctattcatgt caagtatagc taggcgggag agataaatga
      421 gtttatgtta ttttgactat tatcaccaat tggaagagaa attaaggata gaagagccgc
      481 tgatgcttca agctggcact tggatcgcga aacaaattaa tcaaggtggt agattgcaga
      541 tatatgctag ccgcacacta agtggtgtag catttgaatt ttgggatcaa accccggatc
      601 ttgtaccaag tatattgatt gaaaatccag ccggaggtgt ctatgaaacg ctagaaggtg
      661 caggacaggc aattattgat cagctttctg tcaaatcaga agacattttt cttcttcttt
      721 cgaatgaagg aagaaacccg gcaatcatcg aactagctca gtggatcaaa gaaaatggtc
      781 atccattaat cattgttact ggatttgatt tgtcacgaag tatcaaatcg caacatagca
      841 gtggtttgcg attatttgaa tttgctgatt tggttttgga caaccacgcc aatttacatg
      901 atgcagtctt gactttgcca aatctagatc cagcgatctg cggaacagcc tctcttgcaa
      961 cgatcttttt gctgcagcaa gttttgtatt ttacagcaaa acagctagtc caggacacaa
     1021 gtggaaaata gttatccaca tgttgacaaa gttccttaaa aaaataatgt tccacataaa
     1081 aatggagcgt ttgaaaaaaa gaaaacgatt attaatgagg attaacaacg actacttttt
     1141 ttgttttagt tattttaaga tggatcatct ttgattttaa gcttgttttg tttaaagttt
     1201 gttattttta taagttgttt cacagttatg agaaatgagt tataagaata tgtagtgtca
     1261 gaaaaataaa aagtagtgga aaaagagaca agaaagaatc catatggatt ctttcttgtc
     1321 tcttaataca cgttgatgaa agagtcttcc ccaaaactct ttacaaagta attatagtac
     1381 atttgttatc attattgcaa tgaagtttac ctgatataac aaaattgtcc aacaggatac
     1441 ctttttctaa tagaaataaa atacacaaaa attgaaggat agataatgga tatttataag
     1501 tgtttattat tttttttgca atgaaattca atttttcaat gattgtaaaa tgaaaaaaac
     1561 aggacgagat tttctctaat ctaaaaataa aaaaagaatt ttaaggaaaa acagagaaat
     1621 aaaatactta atataaatgg aaagagaaaa aaataatcat acataggaga aaaaaaacaa
     1681 aatagaaaaa agtgattttc taataaatta ttcatgtgga aatgtcattt ttactgtata
     1741 attcatttga ttatccattt tttattcatc aaaattactg aaaaaagaaa ggaagaaata
     1801 aatttgaaga aaacaaattc ttcaggaaaa ccgaaacgcg acttcactaa attatcgaca
     1861 ccccatacgt atgtcattat ttttggtgta gtcatctttg catggatact gacttttgtc
     1921 gttccagcag gaaagttcag cacgcaagat attgaataca aagatgcaaa tggcgaaaca
     1981 agtactcgta ctgttttacg tcaagattcc ttccgttatg cttacgagct ggataagtcg
     2041 tatgtgtttg atcaattaga agaactgcaa gatcatccag cagaacgtga aaaactggat
     2101 gttccggaaa aaggattgga aaaagtcatt gctgacggag aaaaaaatct tacgcaggaa
     2161 aaactagatg aaatctcctt gacagatgat gtgctttacg atcagtacgg cgaaaatatc
     2221 tatgatactt ctaaaaaatt gcataaaaca gccaaaatat ggggaacaga tgattttggc
     2281 ggctttggtt tcttaaattt tgtttttgaa ggactagtat ctggagataa gtatggatct
     2341 gctgtaggga tcgctgcatt gatccttgtt gttggaggtg cttttggtat tattatgcgt
     2401 accggagcga tcgacgcagg tatctatgcg tttatcagta aaactaaggg actggagcgt
     2461 ttagctttac cgctattatt ctttgctttt tcattcggtg gcgctacatt cgggatggca
     2521 gaagaggtaa ttccattctc aatggtgatg gttccatttg tcattgcgtt aggatatgac
     2581 tcgatcgtag cagtaaccgt gacttatgtc gcatctcaag tcggaaatgc gacctcttgg
     2641 atgagcccgt ttagcgtagc ggtggctcaa gggattgctg gaatccccgt gttgtctggt
     2701 gcgacattcc gattgattat gtgggtagtt gttactgcat tagccgctgg ttatatgatg
     2761 atatatgcag aaaaaatccg taaaaaacca gaaagttcgt tgacttacaa atcagatgat
     2821 tatttccgtt ctcatatcaa aaagacatct gatgaaaata aaaaattcat gcttgggcat
     2881 aaattgatct tattagagat gttagttgtc cttgtctgga tcgtttgggg cgtgactcaa
     2941 aaaggctatt acattccaga aatcgcttct caattctttg tgatgggatt agttgctgga
     3001 atcattgctg ttcttttcaa attagatgga atgaaagtca atgacatcgc ttcttctttc
     3061 caatctggtg cagctgattt agctggtaca gcaatcgtag taggtatggc caaagggatt
     3121 cttcttgtct tgggaggatc tgatgcatct gttccttcag ctttgaatac gattttgcat
     3181 gggatcggga cggcgttgac cggtgttcca gctgtcattg gtgcttgggc gatgtacatc
     3241 ttccaaagtt tgttcaactt ggttgttaca tcaaattcag gacaagcagc tttgactatg
     3301 ccaatcatgg ctccactggc agatttagta ggtgtatcca gacaagtagc agttcttgct
     3361 tatcagcttg gttcaggttt tatggacgct tttacacccg tatcagccag cttgattggt
     3421 gtgctaggtg ttgcacggat cgaatgggca aaatgggcaa gattccaaat caagatgcaa
     3481 ggattcctgt ttgttttagg aactattttc atcatgattg ccattgcaat aggtctgcag
     3541 tagtactgga gacctgtaaa taaaaaagta atccaaacag tagataagga ctccaagaac
     3601 cgtcatttta cggtaaaatc aaaggagtaa agatcctatc gtttggatta ttttttaaga
     3661 tcctatcatc agttatactt aaagaaagag gaaaaatgta tgaaaatcat tcgacaaatt
     3721 gaagtgtttg caccagatta cttaggaaaa atggatgtac tgattgccgg tgggaagatt
     3781 ttggctgtag aagaacagct agaaggcggc tacgaaggag tggaagtaga agaactttca
     3841 ggtgagggaa aagtactaac cccgggtttc attgactgtc atttccatat tttaggtgga
     3901 ggaggagaag gcggttatca aaatcgaacg ccagaagtca cattgagcca attgactaca
     3961 gctggtgtaa cgacagttgt cggttgtttg ggaacagacg gagaaggtag agatatgact
     4021 gcgttgatca gcaaagcgaa aggtctggaa gcagaaggaa tctccactta tgtatacgaa
     4081 ggttcgtacc gattgccggt aaaaacagta acagattcta tcatcaaaga ctttttgaca
     4141 attgataaaa ttatcggaat cggagaaatc gcagtatccg atcaccgttc ttctcagcca
     4201 agttttgaag agttcgctcg tgcagtagca gatgctcgtg taggaggcat gttatccgga
     4261 aaagctggga tcatcaatgt ccacttaggc ggaggaaaaa gaaagctaga gctattgaca
     4321 cgaatcgtag aagaaacaga aattccgatc acacaatttt tgcctactca tgcaaatcgc
     4381 acaccagaat tatttgaagc ttgcgtggca tttgccaaac gtggtggcac gattgacttc
     4441 actgctagcg aagatcctga tttttgggag aagacagatg gtgaagttcg cttcagcaaa
     4501 gcactgaaac gattgatcga ggaagatgtt tctttagata atttcacgat gacctcagat
     4561 ggacaaggaa gcttgcctta ttttgatgaa aacaatcatt tcctagggtt aggagtagga
     4621 agtgccaagg cattgctagt agggatcaaa gaagctgtgc aaaaagaaag tatccctttg
     4681 gaaatcgcct tacgagctat aaccagtaat ccagcacgta tattgaaatt ggataaaaaa
     4741 ggaaaaatcg aaattggtgc tgatgcagat ctgtgtatct tggataaaga aacgcttgat
     4801 attgatacag ttatcgctaa aggagaaata atggtccaag aaaaagaagt caaagtatgg
     4861 gggactttcg aaaaaagttt ttaatcaaca gctctaacta tcttttttag aaaacgagcg
     4921 ttctgtttgt ctgtatctgt tgttgatgtt accctgaagg tagatcaata aacaaactaa
     4981 gaggaggaag cacaatggca gatttaaaag gacgttctaa agatatgaaa gataaagtag
     5041 tcggtgaagg aaaagaagca tacggcaaag caacagacga caagagcaaa gaaacagaag
     5101 ggaaagcaca atcactaggt gctgacatca aagaaaaagc tcgaaattta ggcgacgaag
     5161 tcaaagacaa gttttctcga aaagacgaaa aaaaataaaa accacttatt actaattgaa
     5221 tcaagcaaat aaaaaatccg aaccatatct gcgagacaga tatggttcgg attttttatt
     5281 tgatcattat cctgtttttt aaacttcgat tttttgaaat tttttatttt ttagttcaaa
     5341 gacttcatca cagctttttg ctacttcaat ctcatgagtc acgatgataa tacagcgatt
     5401 ttgttcatgg gcgatttctt ggaaaagttt gacgatatct tgtgaagttg tttcatctag
     5461 atttccagta ggctcatccg ctacgattag ttgatgttca cagcagatag cacgaacgat
     5521 agcgactcgc tgctgctgac ctcccgaaag tttggtcacc tgtttttttg ctaatatttc
     5581 atcaattcct acacgagcca gtcgatctaa agcaacttgt cgataattct cttgcttggt
     5641 cttagtgatt tccattgctg ctatgacgtt gtctagagcc gataaataag gaagcaagtt
     5701 gtaagcttgg aaaataatcg agacatcatt tttacgataa cttcttaacc cgattttgtt
     5761 cagtgaacga tcttgatagt atacctttcc ttcttttggt gcatctagtc cagaaataag
     5821 cgaaagaaaa gtcgtttttc cagaaccact tgctcctaaa atagcgtaca tttttccagc
     5881 ttcgaaattc agttctacat ctttataaag cgcatcttgc ggatcttgat accaaaatcc
     5941 caattgttct gtccgtaaca tcaaattcct cctttagttt aataggattt ttcttgggtt
     6001 taatcttaat atccctatag aagctaaaaa gacagaaaac agactgattc caaatgctac
     6061 tccggctaat agtcccaatt gtgcaggttt gacattgatt tccaattcgc tgacttgatc
     6121 agaaacagca aatggattat tcgtggttcc ttgttgacca tcgcgttgac cgccttgttc
     6181 ttgtctgtta cctggcattt gtccaccgcc aggagcttgc tggttttgtg tcgtggtttc
     6241 tgtctattgg tcaagtagct gctgtcccac ggcattcgcg acgacgtttc cgctaagcga
     6301 agcaactcct aatgcaagaa tcatacaaat agccacttcg gtaaacaatt ggagaatgat
     6361 tttacttctg gattctccta aagatagcaa gacgcctaac tcatgccgac gctcccgaat
     6421 ggtaatcata atgatcagag taagtatgat aataccggct acagccacta gtaaaacaac
     6481 atttttagaa aaacttgcca cgttgtttaa aggttccaac attgactgat acatggaatc
     6541 atttgattgt aagctaaatg tatctgtgtc gatcagcttc tcagcttctt tgagaaactc
     6601 atccatttta tctggatcag atagagtgta aatagcagaa tctatcgtgt tatcgtcaga
     6661 tgtcccattt agttcatttg caaaagtgta agaagtgtaa agtgtattcg acggattcat
     6721 gaagttgaat ttcataccca tactgccgct tgtttcgctg gattcataaa ttcctttgat
     6781 cgtcatttca taagtggtat cttcatcttc agtactcgtg attgtgaaag tatctccgac
     6841 tgccaggtca tttgtttctg ctagagtaga atcaatgact acattgtttg tgcctttgtc
     6901 gctgtcatct attccttcac catccgtgat ttttgctgtt ccatcagaaa aattactatt
     6961 ttgtgcagtt gctgacacac cactgatttg aaagcctgct tgagtcattt gcggattccc
     7021 gcccattcct ccagcaggtt caccgcctgc atcagtagtt tctgaactgt cttcacttga
     7081 atcagaacta gtgatggcag ttattccatc ttttgccata gctgaggcgg aactttcaaa
     7141 ggaataactc tttacattat ctaattcagc tattttttcc gcgtccgtta aggaaactgg
     7201 tgtaagagaa aaactgcctg gatctggacg ttcttcagtg gtagaaccgc ttgaagaagt
     7261 ttgttcctgt tttttaaatg aagcttctcg attggcactt aaagtcactg ttgctccaac
     7321 ttctttttgt gcttgattcg ctgcttcttc tgcagcgctt cgaatcgtga ggccagctag
     7381 cacaaaaata agaatggctg tgaacacggc aaacaataac aatgaacgtc cccattttac
     7441 ttttgtactt ttccatgcac gtttcataaa attcatattt tgcatccctc ctagtagatg
     7501 catttgataa tagacaacct atcttaaagc tagcttaaat cttatgctgt ttgcacacca
     7561 tcaacatgag gttctgtata tataaaaagt cactatagtt attgcaaaaa atgtggtaaa
     7621 atgaaaaaag tatgtttcaa accgacgaag aagaaatgaa agaggaatag caaaagaaat
     7681 cctagatgct acagagggat ttttacgtgc atagttgttc taacaattgc tgatactagc
     7741 gatttagttt atttgttgta taataatggg gaacagctga atacttatat aagtattctg
     7801 gctatagcgt ttcgcaaaag atccattttg ttaatgaagt atatccaaaa taaaatgccc
     7861 atccaactgt cagaacgcgg atgtgctggt aattttcctg ctgattctcc ataagttgag
     7921 aaatagtgat tttgcatatg cttcattgga atggctcata tatttagata aagaagaaaa
     7981 tcgacatctt taaacttgga tgtcataaga agaggtgaag tttgtgagta ccattaaaat
     8041 tatcccatta ggcggcgttc gtgaaaatgg aaaaaacatg tatgtcgcag aagtgggcga
     8101 ggatattttt attttagatt gtgggctaaa atatcctgaa aatgagttgt tggggatcga
     8161 cgtcgtaatc cctgatttta cgtatttaga agaaaacatt gatcgtgtag ctggtgtctt
     8221 tttaacacat ggacatgcag atgcgatcgg ggcacttcct tacttgttgt caaaaatttc
     8281 tgtaccagta ttcgggacag agttgacgat cgagttagca aaattgaatg tcagtcgtaa
     8341 tgaagcagcc aaaggattta aggatttcca tgtggtagat gagcatacag aaatagactt
     8401 tggtgaaaca gtagtgagct ttttccgtac cactcatacg ataccagatt cagtggggat
     8461 caatctgaaa acaaaagaag gtagtatcgt ttatacggga gattttaaat ttgaccaaac
     8521 ggctatccca atgtatcaaa cagattatgc acgattggcg gaaatcggca aagaaggagt
     8581 cttagcctta ctaagtgaat cggcaaatgc agaaaatcct cagcctgtag cttctgaagc
     8641 ccaaatagca gatgaagtat ttgatacgat caaatattgg gaagggcgta tcatcgtcgc
     8701 ttgtgtagca agtaatttgc aacgagtgca acaagtattg gatgcagcag aaaaagcaca
     8761 acgaaaagtt gtcttgactg gtcaagattt cgaacgaatt attcgcacag cgatgcgttt
     8821 agaaaaactt caattaccaa gtgaagatct gcttgttacg ttgaaagaca tgaaaaacta
     8881 tgatccagaa gaactgatca ttttagaaac tggccgaatg ggtgaaccca tcaagtctct
     8941 gcaaaaaatg gcaaacggta cacaccgtaa tgtcaagatt gaagaaggag atttggttta
     9001 tatcactact acgccaagca tcgcgatgga aaccatcgtg gcgaaaacgg aagatatcat
     9061 ttatcgagct ggtggaacag tgaagttgat ctctgagaat atgcgcgttt ctggccatgc
     9121 caatcctaat gacttgcaat taatgatcaa tttgatgaaa ccaacatatt ttgtgccagt
     9181 tcaaggagag tatcgtgaat tagctgctca tgcagatttg gctcatgcag tagggatgcc
     9241 atacaaaaat atctatatta ctggacgcgg agacgtgctg gaatataaga acaagcgtat
     9301 gagtgttgca ggaactacaa gtgcagaaaa tgtaatgatt gatggattag gcataggtga
     9361 tatcggaaac attgttttac gtgatcgaaa aatcttgtca gaagacggga ttttcgtagc
     9421 ggttgtcact atcagtcggc gagaaaagaa aatcatttca aaacctcaaa ttacttcacg
     9481 gggattcgtt tacgtaaaag ctagccgtga tctgatgaaa gaaagcagca atatgattga
     9541 aacaatcgtt gagaaacatt tagaaagcaa tgattttgag tggagcaaat taaagcaaga
     9601 catccgagat caattaggcc gttacttatt tgaacaaaca aaacgccgcc cagtgatctt
     9661 gccagtcatt atggaagcta ctcaacgtcg aaataaaaaa taaacaaaaa gagtaagatg
     9721 aacctctcta tagagtgctc gtcttgctct ttttttgcga aaaacaaata atttttgaat
     9781 acagcatccc tcgctttata ataaacgata gaataaaggg agtgaatcaa tgatgagtca
     9841 aacaaaagtc gaacgttatt tagaagaaca aaagatcagc tatcaaccac ttgattttag
     9901 tcatgtggta gaagaatctt tcacagaaga actacaaaaa agagggattg atccagcttt
     9961 gatatgtaaa actctcgtag tgaaaggaaa caaaactggg gtgatcatcg cattgattcc
    10021 tttgaacgat cacttagatt acaaaaaaac gagacaagtg acgaaagatc gtaaagttgg
    10081 ttttcctgga atggattttg tattaatgca tacaggatat ccccacggag caaacacccc
    10141 tattggaata aaactcgcac atcctgatta ttgtttttta gcagacagtt ctttaaaaga
    10201 aaaagaagaa gtaattgtgt caagcggtga aatcgggaga agccttcgga taaaagtagc
    10261 cgatttagaa aagatcgtcc atcctattta cgctgattta attagttaag ggacgagaag
    10321 agaagctaag cagagcagag acctcaaact tgagattata tctgcttggt acttggtgca
    10381 tcctgtatta tctgttacaa ttgctttgta catactgtac tatcaatcca atgaaaatat
    10441 atttagcagc tatatttttt cattgatgtg caagtgatga aatcgttttt aataaaaaag
    10501 atacagagaa aacgcgaggt gtaaaatatg aaaattacgt atcatggaca ttcctgttta
    10561 acaattgaaa tggaaaatgg ccaacgcgtg atgattgacc cgtttattac aggaaatcca
    10621 ttgacagact taactgcaga agaagtaaag acagattggt tgctgattac tcatggtcat
    10681 agtgaccaca taggagatat gattcctatt gcaaaagaaa atcaagccac aattatcagt
    10741 attgttgaga ttgctgatta tgcgaacagc agaggagtag attcattcgg tatgaatatc
    10801 ggtggaaaac atgcgtttcc attcggcgtg gtaaaattcg tacatgcaca gcatagttca
    10861 agctatgaag tagacggtat cgttcagtat atgggcgagc ctagcggaat tattattcaa
    10921 gcagaaggaa aaacgattta tcatgcaggg gatactgctt atttcagtga tctaggattg
    10981 cttgcagaag aattcgatat tgatgtcgct ttcttgccga ttggcgataa ctatacgatg
    11041 gggccagaag atgcagcaaa ggctgcgcaa acaattcgtg ccaagaaagt agttccaatc
    11101 cattacaata ctttccctgt cattgaacaa gatcccgaat cttttgtaga gttactggaa
    11161 gatagtgaag gaaaaataat gagcgtctcg gaaacgctgg aagtgtaggc agaaaatggc
    11221 gacaaaacat gatttgattt tagaatatat tgaaagttta cctgttggca atcgaatttc
    11281 tgtaagaagc atcgcaaaag aattgaatgt cagtgaagga acagcgtacc gtgcaatcaa
    11341 agatgcagaa aatgtcggac tagtttcaac aattcaacga gtagggacca tccgtatcga
    11401 acgcaaatta aaaaaacata ttgaacgttt gacatttggc gaggtcgtca ggatcattga
    11461 aggggacgtt ttaggcgggg cggcaggatt agacaaggtc ttgaataaat tcgtcatcgg
    11521 cgcgatgact aaacatgcca tggaacgcta tattacgcca ggatcactaa tgatcgtcgg
    11581 caaccgggcg gaagtccaaa aattagcatt ggaagatggc gccgcagtat tgatcacagg
    11641 aggattcaat acgactgctg agattgcaaa gctagctgat gatcttgaaa tgccgatctt
    11701 acgcacctct tatgatacat ttacagtcgc aaccatgatc aaccgagcgt taagcgacca
    11761 attgatcaaa aaagatatca tgcttgtcag tgatatctat atgccagctg aaaagactca
    11821 ttatttgcag cagacagata cgatttctga ttatcagcgt ttgtcagaag aaacgcagca
    11881 ttcgcgtttt ccagtcgtca accgccatca tcgtttgatg gggattgtta cggcaaaaga
    11941 tgttttaggg aaatcgccaa accagatcat cgatcgggtg atgacgaaag aaccaatcag
    12001 tgtaaagaaa acaatgagta ttgcctctgt tagccatcaa atgatctggg atgggctaga
    12061 agtcatgccg gtcgtttccg atgacttgac attggaaggc ttgattaccc ggcaagatgt
    12121 aatgaaagcg atgcagcttg tccagcgaca accgcagatt gcagatacga tttcggatca
    12181 gatatctgga aatatccata cgattgatac tgaccgtgaa ggaaatcgtt tggaaaaccc
    12241 taagttcaaa ttcgtagtag caccacaaat ggtcaatggc gttggaacca tttcttttgg
    12301 cgtacttagc gaaatcattt ctgatgtcgc acaaaaaaca atggtgatga accaaaaacg
    12361 aaatatcttg attgaacaag tgaacctaca ttatttgcgg ctgatccaat tggaaagcga
    12421 attagacatt cgtccacgtg tattggaaat cggcagacgt tccgctaaac tggatatcga
    12481 agtgtttatt gaaaacacca tcgtttccaa agcaatcgtt gtttgtcaag taatggaacg
    12541 ttcttagaaa gcaggagtga aatgacagta cagcaagaaa tagtagatac aataaaaaaa
    12601 tacgataaaa tcattatcca caggcatttg cgccctgatc ctgatgcatt aggatcacaa
    12661 gtaggattag ccgaactatt acgggaaagt ttcccagaaa aagaaatacg tcaagtaggt
    12721 gaaacgattg aagggcttcg ctttttagca gaaatgcaag aagttgaaga tgtcttctac
    12781 caaggagcgc tagtcatcgt gactgataca gctaattcac ccagaatcag tgatcaaaga
    12841 tatcagttgg cagaaaaact gatcaaaatc gaccatcatc ccaatgatga cccttatgga
    12901 gatcttgtgt gggtaaatac aaaagcaagt agctgtagtg agatgattgc agaatttgct
    12961 ttgatgtttc ctgaatcttt aaagatgaac gttaaggctg cacggttact ttatgcagga
    13021 atcgtcggag atacagggcg ctttttgtat ccctccacga cgtcccgtac attagagatt
    13081 gcttcgatat tgagaaatta tccatttgat gcaagtgctt tgaacagaga gattgaacaa
    13141 atgccgatga aagtcgctaa actttccggt tatctttatc aaaatatcca ggtggatgaa
    13201 aatggtgcag gaagaataat ccttccgcaa gaaattcttg ataaatatgg aatcgatgat
    13261 tcagagacag cttcgatcgt ttcacttcct ggagtgattg acgaagtgct ggcttggggg
    13321 atttttgttc agcagccttc agggtattac cgcgtacgtt tacgttctaa ggggccgatc
    13381 atcaatgaat tggctaaacg ccatcatgga ggaggccatc cattagcaag tggtgcgaat
    13441 gcaaaagatt tagcagaagt agaggaaatc tataaagaga tccaagatat atgccaatcg
    13501 tataagagca gaaaaacaga atgatacttc gttcgaaaac gtgccttttg tagtaaaaat
    13561 cacaaatgta tcttttcaag atcttctttt tccgttacaa tagtgctcac taaagatttt
    13621 aaaggagaaa gaagatgaca ttaccaaatt gcccagaatg tggctcagag tacacatatg
    13681 aagatcgagg cttgttgatt tgcccagaat gcgggaacga atggaacaaa gaagaacaag
    13741 aaactgtcat agaagacgga ttagtggtat tagatgcaaa tggaaaccgt ctgttagagg
    13801 gcgatagcgt gacagtgatt aaagacttga aagtaaaagg tgcgtcaggt gccattaaac
    13861 aaggaacaaa agtcaagaac atccgtttag tagaaggcga tcataatatc gattgcaagg
    13921 tagaaggatt tggaccgatg aaactgaaat cggaatttgt gaaaaagaat taaagaatat
    13981 tcaaggtctt ttcacattct tttcctacta ctaatgataa aataaagtaa acgaaaagga
    14041 gtgaaacgaa aatgtatggt tatggaatgt atggtttttt agatccgaca tttcttttgg
    14101 tcattcttgg attagttatt tccggaattg cgtcagcgta cgtcaatagt actttccgaa
    14161 aatacgatca agtgagaagc aaaaacaatg tgactggtac acaagcagca caatatatat
    14221 tacaaagtca acagataaat aatgtcggtg ttcaacaaat tgccggagat ctcacagata
    14281 actacaattc aggtaataag atgttgagtt tgtctcaagc aactgcacag tctacttcag
    14341 ttgctgcgat aggtgtagca gctcatgaat gcggacatgc ggtacaagat gcttcgggtt
    14401 atgtcccatt gaagattcgt gcagcacttg ttccagcagc taactttggt tcgatgattt
    14461 cgttcccctt gattatggta ggtgtattgc ttagctggaa ctctacgtta atcaatatcg
    14521 ggattttcgc tttttcttta gcattacttt tccaattggt gacattacca gtcgaattta
    14581 acgcgtctcg gcgagcaatc caaattttga gtgaaggcgg actactgacg gaagaagaag
    14641 taccgatggc aagacacgta ttatttgcag cagcactgac ttatgttgca gcagcgcttt
    14701 cgacattcct gcagctgttg cgcttgatct tattgttcgg cggcaaccga agagattaaa
    14761 ataaagaagt tgtgaaatca gcgctttgat ctgagctaat accgagagtt agctgattga
    14821 ataccattta tttggaata
//
LOCUS       DACBZK010000065        14631 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.068, whole genome shotgun sequence.
ACCESSION   DACBZK010000065 DACBZK010000000
VERSION     DACBZK010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14631
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.068"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..1416)
                     /gene="nhaC"
                     /locus_tag="IVD66_002129"
     CDS             complement(<1..1416)
                     /gene="nhaC"
                     /locus_tag="IVD66_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAP6146329.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(1819..3042)
                     /locus_tag="IVD66_002130"
     CDS             complement(1819..3042)
                     /locus_tag="IVD66_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAP6146330.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(3073..3912)
                     /locus_tag="IVD66_002131"
     CDS             complement(3073..3912)
                     /locus_tag="IVD66_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HAP6146331.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(3929..4609)
                     /locus_tag="IVD66_002132"
     CDS             complement(3929..4609)
                     /locus_tag="IVD66_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6146332.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(4611..5684)
                     /locus_tag="IVD66_002133"
     CDS             complement(4611..5684)
                     /locus_tag="IVD66_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6146333.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     gene            complement(6331..7002)
                     /locus_tag="IVD66_002134"
     CDS             complement(6331..7002)
                     /locus_tag="IVD66_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP6146334.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(7089..9767)
                     /gene="mgtA"
                     /locus_tag="IVD66_002135"
     CDS             complement(7089..9767)
                     /gene="mgtA"
                     /locus_tag="IVD66_002135"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HAP6146335.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            10426..10863
                     /gene="ndk"
                     /locus_tag="IVD66_002136"
     CDS             10426..10863
                     /gene="ndk"
                     /locus_tag="IVD66_002136"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HAP6146336.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(10885..11751)
                     /locus_tag="IVD66_002137"
     CDS             complement(10885..11751)
                     /locus_tag="IVD66_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP6146337.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(11911..14004)
                     /locus_tag="IVD66_002138"
     CDS             complement(11911..14004)
                     /locus_tag="IVD66_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP6146338.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
BASE COUNT         4247 a         3137 c         2497 g         4750 t
ORIGIN      
        1 ttgttctaat tgcgctgtct tgcttactgc ttcttgcggt ttcacaaatt tttttgagat
       61 tccccaacct gtgaaggcac tgaccatcga aaacacagga gaaagcaaac tgaaaaatac
      121 gaatggcaag taagtgagtg taggaatacc aaatgtactt gctacgaaac ttccggcaat
      181 tccccaaggc actaagtagt tgattactgt tccaccatct tctagcgttc tacctaatac
      241 agttggatca aatcctgctt tttcataagt ttctttaaat gcattaccag gcagaataac
      301 agataggaat tgttcaccaa taaaaatatt tactccgata cttgtcatca atgttgtaaa
      361 aatcaaattt ggtgtgttcg tcatctttct tgatactcgt tccatcacgg ttgagatcaa
      421 gccaaattcg atcaacaatc cacctaatga caaagttaga ataatcaatg acacagtagg
      481 catcatactt tcgattcctc cgcggctaag cagtgaatcg atttgttggt ttccagtatt
      541 tgaaacaaac cctgattcga tgaccccagc caacttcgtt aaggaagttt gtgggttttg
      601 aataaaaatc attcctactg ctacagcgat attcaacaaa atcgttaaaa ttgccggcac
      661 ctttttccat gcacacagta acattaaaaa taaaggaatc agtgaccaga ttgaaatagt
      721 aaagtttgct tctagaacat cagtcacttc acgaatagat gaaagacttg cggctttact
      781 tgtgtgtcct aaaatcatga ataaaaagaa agaaacaaca aatgccggga cagttgacca
      841 catcatatgc ttgatgtgtt tgaacaaatc ggcatcaaca atagctgctg ctagatttgt
      901 tgattcggat aatggagaca tcttatctcc aaaaacggca cctgaaacaa tagctccaac
      961 aaccagcgct ggatttaagc ctagtgttgt cccaataccg aaaaatgcaa tcccaatcgt
     1021 tgacataaca gtaaaggcac tccctacagc gctacctacg attgcacaca caacaaatac
     1081 agaagggaca aaccactgga cactgatcaa tttgaaccca atgaccatta gagttggaat
     1141 gatccctgct tgtatccata cagcaatcaa tgaaccgact aaaataaaaa taaagattgg
     1201 gatgattcct ggtttgatgc cattgatgat tccttcgtgc agccaatctg tcgggtatct
     1261 ttttatcact gcatacaaca tgaccattcc gatcgctgct aagatcgtga tattaggtga
     1321 gacctttaat ccgacaacgc caatcgcaat gcctaaaaca ataaccatta atacaagtgt
     1381 tgcttctaaa aaacttggtg ttcctttttt tcccatgata atctctcctt ttttagttgt
     1441 tcttatgttc taaaaaagtt aagatatcgg attactccgc cgcaattcat ccgcgattcc
     1501 tcctttataa aaataaaaag acctgtttta aactaaggac gaatgactcc gcggtaccac
     1561 cttaattaaa aacagatctg tttttcactt tcaaactttt attcaaatgt atggactttc
     1621 catgtaattc gtcaattagg cttgatcggt tcacagcgac caccgacttt ctgaacaaaa
     1681 cacctaaccg ctactgcgtg aaaagttgac ttgtacgaag tttaccttcc ataagatcat
     1741 ttgtcaatga aaaagaaaat attttttcat ttttctgaaa attattttta taactttcac
     1801 acacaagttt attttttact agaaagtagc gccctcttgt ttttttcttg ctactatttc
     1861 ttgatgttct tgcttgattc tttctaatag ctttggctct ttcaacagat caagagctgt
     1921 attggcgagt agttctgctg caatcgcaat agaagcaagg cctttgtcac ttttagcagc
     1981 agctttgaat tcttctgtgt gtccggcaat atatgtctca gagattgcta ccgtaggctg
     2041 gattgttggt atgacttggc tgacatttcc tacatcagaa gaaccgagac ttgttctttg
     2101 ttccgtttct atttcttcat ctggaacacc tgcttctttt gcatgctgga agaataagtc
     2161 atcaaaagaa ggagtaacga tgacatcatc aactgcattt tggaacaatc caaactcaaa
     2221 agtcgtgccc gtacttatcg cagcacctcg tacgatattt tccacttttt catatacttt
     2281 atctaatgtt tgccgatttc ctgcacgtaa atagaaacgt ccagcagcgt aatctggaat
     2341 gacgttggca gctactcctc cgtctgtaat gatcccatgg atattgacat cttttggcaa
     2401 ttgcaagcgt agagcgttga ttccattaaa cacttggatc aatgcttcca aagcatttac
     2461 tcctttttca ggtgctgctg ctgcatggga agcgacaccg taaaatttga tgtcgactgg
     2521 atcattcgct aaagattctg tcgttttccc ataacgaaaa gctggatgga cgcataacgc
     2581 tacatcgaca tcctcaaaaa aaccttctcg aacaaagctg cctttagctg atccgttctc
     2641 gcccccttct tcccctgggg tgccatatac acggatttct ccaccagttt catcaatgaa
     2701 ttgcttcact atgctggcgg ctaatacgga gtaagtacca aacaaattat gcccgcatgc
     2761 atgaccaata cctggtaaag catcgaattc tgccaaaaag gcaattgtgg gaccgggttt
     2821 attggaaata taacgtgcat caaaggctgt tcggtgtcca gctacttctt tttctaccca
     2881 aaacctttct ttttctaatt gtttaatcaa cgctgctgag gaataaaact catagttact
     2941 tacttcagga tgttcgtgga tatctagagc aagtgcttga tattctggta aacgatattg
     3001 gattagatcc ttcaattggt ttgttgagat tgttgttgtc ataaaaaatt cctcctatgc
     3061 tagtcatttt tcttattttc tcccgaatgt ttcccatgca ggcacgcttg atccttttga
     3121 tgttttctcg attactttga ctgtgtcttc tgtttgataa gcgtctacta ttttttgata
     3181 cgttttattg ttttcatctt cttttcttgc aacgatgata ttcacataag gacgtgcatg
     3241 gtcatccact ggttctaaga agatggcatc agaagcagga ttaaatccag catctacagc
     3301 tacaccgcta ttgatcactg aaatgtctac atctgacaaa gcacgtgctg tttgggaagc
     3361 atctaattca gaaatgtcta gattttttct attctcggta atatcagaaa cagtgggcgc
     3421 ttgtcctttt gccttatcca ctttgatcaa tccagcagtt tgcaataaca gaagagctct
     3481 gccgccattt gtaacatcat tagggattgc tacttttgct ccgtctttga tatcagctac
     3541 atccttcaaa gtgttagaat aaattcccag cggtgcattg acagtatttc cgatcgatac
     3601 taaatcagtt ccgtgttctt tattgtaatt gtctaaaaag aattgatgtt ggaaagaatt
     3661 caaatcaatc gatccatctg ctaaagccac atttggttga ttgtaatctg taaatttcac
     3721 gtattccaaa ttaatgttct cctttttcaa acggtctttc acgttgtccc atacatctgt
     3781 atcttctcca ataatcccta gttttacgat agtttctttt ttgtcagttg tatctgcttt
     3841 tccttggcta caccctgcca accaaataat tgctacaaat gtaatgacta caaaacgaat
     3901 aatttttttc attttttctc ctccactttc aatgtgtaat ttttttaatc agttgattac
     3961 tgataaattg acttaaaaaa actaagatta gaatcaataa tgtagccaca atcgttacat
     4021 ctgtttggaa tcgattatac cctctcgata tagcaagatt ccctaatccg cctgcaccta
     4081 ctgctccagc catggtagtc agtccgatca cgttgatgat agtcaacgcc gagacccgaa
     4141 tgataccagg caaaccttct aacaaataca cacgtaaaat gataccgatt ggactggttc
     4201 ccatcgcttc tgccgcttcg atcaccccag gatcaacttc tagcagtgcg ttctcgattt
     4261 gacgagcaaa aaacggaaca actccaaaaa tcaatggcac taaagctgct ttcgcaccaa
     4321 tcgtcgttcc aactaagaaa cgagtagtca atgctaaaag agaaagcaag ataatgaaag
     4381 ggatggaacg aatgatattg atcagcttat caagtatttc aaatagcaga cggttagcta
     4441 gtaatccatt agggcgtgtc actactaacg tcacacctaa gatgattcca atcatcccgc
     4501 caatgaatgc tgtccaaaaa gacatatata gtgtttgctt cgtcgcttcg acaaattcat
     4561 ccggaatcaa ataaacattg ggcaaatatg ttttaaagaa atcagtcatt ttatcttcct
     4621 ccttcgatca ctttgatacg actatctaaa tcgttttttt gtaaaatatt tatttttaca
     4681 ccagatttga tcaaataatc caatgctttt ttccgctgtt tggtttctcc agctaaagta
     4741 acgatcaaac tccctaacgg cgtttcttgt aataactcta cattgccata taaaatattc
     4801 gctgttactt gatatttgct gtacagatga gcgattagag gttcgttcgt ctgatttcca
     4861 atataactta attccaccag ccatttattg gcgatctgat cggcaaaagc agaatgggca
     4921 atgatcgttt ctaatgcttg gtcaagatga gtagctgttc gaataaaatc tttggtcaat
     4981 tcttcttcag gattgctgaa gatctggatg ctgctacctt tttcaacgat tcttccatct
     5041 tccataaccg ctaccttgtt gcagatttct ttgacaactt gcatctcatg agtgatcagg
     5101 acgattgtta aacctaactg gcgattcaat ttttttaaca atgcaaggat ctgaagggtc
     5161 gttttcggat caagtgcact ggttgcttca tcacataata ataccttagg ttcattcgcc
     5221 aaagctcgtg cgattgctac tcgttgtttt tgtccccccg acagttgttt aggataagca
     5281 gatgcttttt cttccaaacc gacaagttcc agtagttcat tcactttttg acgacgttcc
     5341 tgtttcgatt ttccagaata ctttaaagaa aaatcaacgt tgtcaaaaat agttcggctt
     5401 tccattagat tgaaatgctg aaagatcata ccgatggcct ttctttcttt tcgcaattct
     5461 ttgggagaga gctgactcag attcgtctga ttgacaatga cttctcctgc tgttggtttc
     5521 tgcagcaaat tcatcacacg aactaacgta cttttccctg cacctgagta accgacgatt
     5581 ccataaacat cgcctttttc aatcgttaaa tctacagaat ctactgcctg tatctctttt
     5641 tctttttgtt tgaaacatac agaaacatct cgcaattcaa tcattaaaat tcctccttat
     5701 ctaaaaaaag cgtcctcaag aaaatgaaaa tgtcattttc ttgaggacgc ttttttgcgt
     5761 gttaccacct catgttcaag ctgtgttcac acacaactcc tcttcaagta cgatcatact
     5821 ctagcaagat atcggtcgca gccgtcatcg ccttacatct atgctcggga tgaattgctc
     5881 gatggccatt ttccaatagt cgttccttgc ttcttctcag ctaccgaagc tctctgtcaa
     5941 aggttcttct atcgtactta ccatttcaat gcaaataata ttcaaaaaaa aagtcctttt
     6001 actaacataa actatgtcag taaaaggacg acgtatcgcg gtaccacctt ttttcggaag
     6061 tttccttccc tcaagcccaa catctcaaaa agagagattg gcgttcgttt taacggtcga
     6121 acagttccga atttgcctac ttatcgacaa attattctcc aaggccattt tcagcttttc
     6181 ttacttgact cttctcacca gccagagcct ctctgcaaag tttccaaact tactttcctt
     6241 ttcaacgaaa tcgatatttt gttgttggga ttaatctaca tgaggaaaac tgaaaagtca
     6301 agtacgaaat tcaaattatt ttttctatat ttatttttct gtttttttat ttaacatttc
     6361 aataacagtt cgaagatctt ttccttccgc aagaagtttc aatttttcct tttcttcgac
     6421 ggtataattt cggacaaaac tggaatcagg tatcaaaaca acgcctaatc ctgctcgtga
     6481 agcagctgtt gctcctacta aagaatcttc cactgcaaag gctgaactag cttctaatcc
     6541 tgttcgttcc aaagctgtca gataaggaat cggtgaaggc ttgttctccg acacttcgtc
     6601 tccgaatgta aacgtgtcca agtaatcagc taatttaaag tgatccaaga tatctgttgc
     6661 tcttttcgta acagtggtcg tagcaatgcc tagtttcata tgacgttctt ttaagtctgc
     6721 caatatttct tttgcatatg gttttaagtg gatggctccg cttgtcagct gttgataaaa
     6781 atattcttca cgcttcgctc ggacttcctg tactttttca gggctacctg ctgctttcac
     6841 taaaatatca aaactttgtt tccagttttt tccgccccaa gcgtcaacga tttcttttgg
     6901 gatatggata tcaaattgct gaaatcccca aagccagcca tcacgatacg ttttttctgt
     6961 gtcaactaac aaaccatcta aatcaaatat tgcacctttc atctatacat taatcctttc
     7021 caaaacaata cacatagttt agcacgactg gtccaaaaag aacagaagca aagaaccagc
     7081 cttctcgttt ataagagttc ttggaatcga cggatataga ttttcttcac agctgtcaca
     7141 agcgccagat aagcgatgac tgtagcaaat aaccataacc agtaattgcc aggaagtggc
     7201 atcaagccta attcagcacc aaaacttgta aaaggaagga cagaaccgac aataattcct
     7261 aatgtagtga taacaaacat ggcaaatgtt gcgttgcttt ggataaatgg tactttcggt
     7321 gtacgcagtg catggagcac taaggtttgt gtccatagtg attcgacaaa ccatcctgca
     7381 tggaataatg cgatgaaaat cactcgctgt gaactatcca atgtatggaa acttccgccc
     7441 actacagcag gacaaataac aaaatacatc aacaagtaag tagtaatatc aaatatcgaa
     7501 cttgttggac caaagtaaac catgaattcc ccaatactag atgcattcca tttttttggc
     7561 tcgtccaaat attctttatc catccgatcc catggcaagg aaatgcagga aacatcatag
     7621 atcagattca aaaacaaaag ttgtaaaggc agcattggta aaaatggcag gaacgtactt
     7681 gcaatcagca cggaaaacat attgccaaaa ttagaacttg ctgtagcctt gatatatttc
     7741 atgatattcc caaaagtttc tcgtccagaa agaaggcctc tttccaaaat cgtcaaatct
     7801 ttttctaaaa ggatcacgtc tgcagattct ttcgcaatat ccacagctgt atctacagaa
     7861 ataccgatat cagccacttt cattgcagga gcgtcattga taccatctcc taaaaatccg
     7921 acagtatgac catttttacg taaagctgtc gtcaaacgtg ctttttgctg aggattcaat
     7981 tttacgaata cttcatggtc ttcagctact tgtgctaatt catgatcact catttccgag
     8041 attttctcac cggtaaccaa ttcattgatc tctagaccta cttgacggca cactgaacgt
     8101 gtaactaatt cgttgtcccc agtcagaact tttacagcta caccatgttc tttcagagct
     8161 ttcaacgctt gtttcgttgt ttcttttggt ggatcaagga aagcaagata accaatcaaa
     8221 accatgtctg actcatcttt gactgaaaat tctccaacga cgcttggatt ggtcttttgt
     8281 gcgacaccaa tcactcgtaa gccatcttca ttaagtgact gtacttttgc aagtacggct
     8341 tcttttcgtt cttttgttaa tggtgtaaca gtaccgccaa gatcaataaa tttagaaatg
     8401 ttcagcattt cttcaatcgc gccttttgtg atcatttgtg ttttaccagc tggatcagca
     8461 accacaacac tcatacgacg acgttcaaaa tcaaaaggaa tttcatccac tttttgataa
     8521 ttgatcttat ctgtatctaa agtttctgtt gcttcatcaa tgatagccac atctaacaaa
     8581 tttttcagcc ctgtttgata gtagctattt agatacgcat ggcgcaaaac acgatcatct
     8641 tcatttcctt cacaatccat atgatattca agaatgattt tatcttgtgt caatgtcccc
     8701 gttttatccg tacataacac atcgattgca ccaaagttct ggatggcatt caaatttttg
     8761 atcactgttc cttttttggc catcacactt gctcctttga ccaaattcgt cgtaacgatc
     8821 attggaagca tttcaggtgt tagaccaact gctacagata gtccaaaaag aaaagcttct
     8881 agccaatccc cttttgtaag cccattgatg acgataactg ctggagccat caatgacata
     8941 aatttgatca gtagcatgga tgttttatgg atgcctaatt caaagcttga ttgaattggt
     9001 ttttcagata gcgtttctgc tacatgacca aatagtgttt catttccaac agaaacaatg
     9061 attccttccg cacttccact gatgacatta cttcccataa agacaagatt ttcgtaactt
     9121 gtttcgcttt gctgatcgtc ttcacatact ttcgcatgct tttctactgg atagctttcc
     9181 cctgtcaatg ctgcttggga aatgaataaa tcctttgcgg acaataaacg catatccgct
     9241 ggtatcatat cccctgctga aagccgaaca agatctccac agacgatttc ttccatagga
     9301 atctctgtgt actttccatt acgttttaca gctgccgtta ctttcacaag tgatttcagt
     9361 ttttcagccg cttgattgga acgtacggac tgaatcaacg tcattgtccc gctgacgata
     9421 accatagtga agataatggc tacaccgaaa agatctttat ctccaggagc tgctaataca
     9481 tattccgtga tgaatgaaat aattcctaat gcgatcaaca ctaatgtaaa tggcgtgatg
     9541 tatgctttca atatttctac aatgaatggt gtttttttgc catatgaaat cgcattttca
     9601 ccgtaatttt ctcttgaacg ttcgatttgt tcttctgtca atccatttgc tgatgcatgg
     9661 aatagttcaa ataattcttg tttcgttttt ccagcaaaag ctgcatagat tttttgtgta
     9721 tctttctttt tttccatctc aatctctcct ttgtgtccaa aagacagctg ttctcgctgc
     9781 ttttggtctt tagctattca tcggatcgat agagaaaaaa ctgaaagggg ctgagaacag
     9841 atagataata gccctggcct ttcctctaga tccttgtttt tcgaatgact gtcatccatt
     9901 tgttctcatc tcctttacta agtaatttta attcatgact tccaatcatt tttcgaatag
     9961 ttatttttcc aattagacca cctccttttt atttttcacc gatggggatt tgcggcaaca
    10021 aaaaaacctc tcgccaaata ctcagcgaaa ggtttgaaaa agcatattaa aaaaagcttc
    10081 tcagatctca tcgttgagtt ttgacactgt acaacgtaaa aagcagatac ctgcttttag
    10141 ctaccttatg aaaagcctta tctcgacaat tcctgttcta cccattggcg tctctcgacg
    10201 tttttgggca gtagcctatg tttgtatagg agcctcacct aacaaatctt attcggtttt
    10261 ccttcgttaa tataacaact aaaaaagagg atgtcaaatc aattttccat gtttttcata
    10321 ctttttttaa aatacacacg ttatattcct gtctcacgcg gttttatttg tctcattttc
    10381 cacctcccgc tataatagaa atatagtagg aaacgaggtg ctgttatgga aagaacactt
    10441 gttattatca agccagacgg cgtgagacgc catttagtcg gaagcatcat ccaacgtttt
    10501 gaagcaaagg gactggccat tgctgaaatg aagtttgaaa ctatgactcc tgaattagca
    10561 aaagaacatt atcagcactt gactgagcgc agtttttttg atgaactgat cgattacatg
    10621 acttccggtc ctgtcgttta tcttgtgctg gtcggcgagg aagtgatcga tatcgtccgt
    10681 aagatggttg gagcaacaaa agctgccgat gctgttccag gtacgatccg aggagactac
    10741 gcgctgccgg ggactgaaaa catcattcac gcttctgatt cccgtgatgc tgcggtaaaa
    10801 gagatcgccc gctttttccc gccattcgat ataaacaaac cgtctgaaaa agcggcgaag
    10861 tgatacaaat tctaaactgc tggtctagtt gctgggttca gcaatggcca gcagtttttt
    10921 ctctaaggac ctccgttgat tctttcctaa catatattcg agcactgtga agaattcttg
    10981 gtagtctttc gtcttttctt cccctaaagc agcagaaatc aatctttgat aataatctgc
    11041 catcaatgtt tcatagatca ctgtacttct ttctttatgt gctaagctcc gtttcatatc
    11101 ttcattcaca ctacgtgcct ttttcaaccg accattttct atataaaacg aagtcaggtt
    11161 cattaaaaaa gtaaagagat actgctcatg attgttcaac tgtgctaatc gtcgcattct
    11221 ttttttgatt ttcaaataat tgttctcaat gaaccgatca ctgaatatcc aaggaaaatc
    11281 agctagaata gatagttcaa attgaccata gtctggtatc tgcatcaagt attcttcaat
    11341 gattcggcat tcataacgta aaaattcaaa ttctgtctca gatacttctg ttttttcgac
    11401 catgtgaaga ttcaaaacca aataatacag atcttctgtt ttcttaaaat gcctacggtt
    11461 attgctgatc tctttataag gatcaaagct gtcttcttgt acccgatcta gcattcgtct
    11521 ttttttcttt aactttattg gttcatccag ctggtttcgc atccattcat attctgcaag
    11581 tgtcatgttc attcgctcta aaaatgatct caatgttaca aatgacattt ttttcactga
    11641 atttgtctca atcccgacta gagaagtctt aaaacagatt ccttccgcta attgggactg
    11701 tgtcaacttc ttgttgactc gaagtttctt gatcaattca ccatcataca taatagttct
    11761 cctttttaat ttaaattttt ccacattcaa taaatagata cgttaaaaag gaaaaataca
    11821 cgaaaaaaat aaaaaaatgt ttttttcata aaaaatacca accatcaagc attagaatgt
    11881 tgtctaacta ctgaaggttg gtttgattgt ttattgatta tttttttgct gttcaacgtc
    11941 tgttcttgtt actggatata agttggttgt tgttttatta ccattttttg aaaagacact
    12001 tgtcgaatgt tcgccttttt gcttttcgat tgcttcatta cgttccgctt catttttata
    12061 gtcatatttt ttcggatcaa tcgtctcaaa tccgtttggc acataaaacc gcaagagatt
    12121 ttcctgattc agcttatctg aaagacttaa cgcagtcttg actttttcct gatctttgga
    12181 gatttcctca tcgattcctg ctgctttcgt atcgatgatt tctcctgtct gattattgta
    12241 agcttttcct cctaggacgg tgtatttggg tgtcacaaag ttcccatttc gaaaagcaac
    12301 tacttgatca tgctgagaag ataataagtc tgtaccaaaa tgaagataat ctttatcatc
    12361 gattcccaat agatgtagta atgtcggcaa aacatcgatt tctccaccgt attcatgatt
    12421 gactgtccct ttagtataac caggcatatg gatcatcaat ggcactcgtt gcatctgtgc
    12481 gttgtcaaat tcatcccatg tatctggatc tttaccaaga gcgcttgcta aatctttatt
    12541 atctgtattc gagatcccaa aatgatcccc gtaaatcaca aagattgaat tttggtaaat
    12601 accagatttt ttcaaatacg taaaaaattg ttccaatgat tgatccagat aatgtgccgt
    12661 tcgaacataa ttatctactg tgctattgcc agtattcaaa gatggaaagt cgaaattctt
    12721 gtcatccgta taataaggcg tgtggttggt tacggaaaga aatttcgtgt aaaacggctg
    12781 ttgtagatgc tcaagatatt gggcagattc tctgaataaa tctttatcta atatcccata
    12841 acctaacgtt tcgtcggatt catcaaaata agatcgatca aagaaattgt cataacctaa
    12901 gtttttatat acatgatctc tattccaaaa actagctaca ttcccatgga aaacagcgct
    12961 tgtatagcct tgcttttgtc caaggatcgc tggtgcggct tgaaagacat tgtctgaccc
    13021 aagttctgtg aataatgagc cttgaggtaa accaaatgtg ccagtttcca acatattttc
    13081 agcatcactt gtctttccct gtcctacttc atgaaagaaa ttgtcaaagc tgatcgttgc
    13141 ttgattctgg aaaatactat ttaaaaacgg tgtgacttct tgtccgtcta ccttcatatt
    13201 aatcaaaaac tgctggaaac tttctaaatg gagaacgatc acatttttcc ctttagcgat
    13261 cccaaatgtt tcgggatttg gctctgcata atgtttcttt gtataatcta aaacttcatc
    13321 aatcccatta ctgcttgcat gcgcgcgaac actgctagtc attcctgttt tgattccgtc
    13381 ataaatagta tacgcatcga ttcctagata tttgacaata tatgaacggt caaatgttcg
    13441 ctgcagcaat tgtggacggt tggcttcgct cagcgctaga tttcctgaaa aaataagccc
    13501 tgaaagacag gtaacagcga tagccatcgg tttgccgaca gggttgcttt tgataggtat
    13561 tttcttgacc ttcaaccaaa ccagtagccc aatgaacaca gcgatatcca gccagtagat
    13621 gacatcatgg ggcttcatca aagaaaagga gcttcctgac aatccttgcg acactttcga
    13681 aaagcctaat acagatttga ctgtaatgaa atctgtgaat tcccgataaa aaataatatt
    13741 caagtacaac aaaagcgtat ttaaaatatc aatgatcaaa agaatagcta acgctggctt
    13801 tggcttttta atatacaaag aaaggccaaa aaacaataag gtagtcgcaa ttgggttgat
    13861 ccacaagata aagtactgga tcgtaccttc cacacctaat gaaaaatctg catagtaggc
    13921 aatgatcgtc ttcagccaga aaaagaaaac agctgtcaaa acgattgcta aacgattttg
    13981 gcacaatttt ttaagttgtg tcacgtatat cacttctctc tattcacatt ttttcttatt
    14041 ttgctcctga aaaatgaaaa tttcctaaaa aagttgttat cttaagattt ttttattctt
    14101 tctaaagatt attccgtcca cttttcacag cataaaaccg ctgcgatgta agcgattaaa
    14161 ctaatgaaga gataaaagtc ttgtggtgac cgcttcactc cacggtattc aaaagccagt
    14221 ttctcggtat tcgtacaaaa aaagaggctg tgacaaaatt cttgtcgcag ctccttattt
    14281 cttgatgcag gacagctttt tcacaacttc ttccttaaac ggtgttctcc tgccaactcc
    14341 tcggccacaa gtcacaatat ttataaaaca tgagaagctg ttttttgaaa ttgttccttg
    14401 tggctcagag ttaaacggca ggctcaagac ctcttgatac acggtgttca atcagctgac
    14461 cctcggtatt agattatgtc aggacgctaa ttttacaacc tcttggtaaa cggtgttcaa
    14521 aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa tataaggagc tattttttga
    14581 aattgctcct tgtggctcag agttaaacgg caggctcaag acctcttgat a
//
LOCUS       DACBZK010000066        14553 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.069, whole genome shotgun sequence.
ACCESSION   DACBZK010000066 DACBZK010000000
VERSION     DACBZK010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14553
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.069"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            1..813
                     /locus_tag="IVD66_002139"
     CDS             1..813
                     /locus_tag="IVD66_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HAP6146339.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            810..1610
                     /locus_tag="IVD66_002140"
     CDS             810..1610
                     /locus_tag="IVD66_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HAP6146340.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1771..3039
                     /gene="rseP"
                     /locus_tag="IVD66_002141"
     CDS             1771..3039
                     /gene="rseP"
                     /locus_tag="IVD66_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HAP6146341.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3107..4816
                     /locus_tag="IVD66_002142"
     CDS             3107..4816
                     /locus_tag="IVD66_002142"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HAP6146342.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5028..9380
                     /locus_tag="IVD66_002143"
     CDS             5028..9380
                     /locus_tag="IVD66_002143"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HAP6146343.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            9524..9997
                     /gene="rimP"
                     /locus_tag="IVD66_002144"
     CDS             9524..9997
                     /gene="rimP"
                     /locus_tag="IVD66_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HAP6146344.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10021..11196
                     /gene="nusA"
                     /locus_tag="IVD66_002145"
     CDS             10021..11196
                     /gene="nusA"
                     /locus_tag="IVD66_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HAP6146345.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNSKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11218..11511
                     /locus_tag="IVD66_002146"
     CDS             11218..11511
                     /locus_tag="IVD66_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HAP6146346.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11508..11819
                     /locus_tag="IVD66_002147"
     CDS             11508..11819
                     /locus_tag="IVD66_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HAP6146347.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11832..14138
                     /gene="infB"
                     /locus_tag="IVD66_002148"
     CDS             11832..14138
                     /gene="infB"
                     /locus_tag="IVD66_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HAP6146348.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14165..14512
                     /gene="rbfA"
                     /locus_tag="IVD66_002149"
     CDS             14165..14512
                     /gene="rbfA"
                     /locus_tag="IVD66_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HAP6146349.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
BASE COUNT         4959 a         2575 c         3248 g         3771 t
ORIGIN      
        1 atgttacgtt tttttccgca aaaaaacaaa tatattcaag aaaaaagcga atttcaattt
       61 aataccgatg gaccaattcc tcagcacatt gccatcatca tggacggcaa tggtcgttgg
      121 gcgcaaaacc gtcgtttgcc acgagttgct ggccataaag aaggcatgga aacagtaaag
      181 aaagtcacaa aaaaagcatc aaggcttgga gtgaaagtgt tgacgcttta tgccttttcg
      241 actgaaaact ggaagcgacc aaaagatgaa gtaagttttc tcatgcaact acctgtcgac
      301 ttctttgata cgttcgtacc agaattgatt aaagaaaatg tcaaagttca tgtcatgggt
      361 tatgaaaacg tattgccaga acatacgcaa gatgctgtaa gacgtgcaat tgagcaaaca
      421 aaaaacaata ctggaatggt attgaatttt gctttgaatt atggaagtag agcagagatc
      481 gtgactgctg tccaagaaat tgccgaagaa gtagcaaaag gagaaataca cgcagaagaa
      541 atcgatgatg aattgattgc taagcattta atgacaggtt tcttgcctaa agagttacaa
      601 gatcctgagc tgatgatccg tacaagtgga gaagagcgaa ttagtaattt tctgttatgg
      661 cagatcgcat atagtgagct gtattttaca aaagcgcttt ggcctgattt tgatggtgcg
      721 catcttgaag aagcaatcgc ctcttatcaa aatcgagacc gtcgattcgg cggtgtaaaa
      781 aaaacagaag atgagaaagg ggatcagtca tgaaacaacg tgtgatcaca gcagctgtgg
      841 cgctagtctt gtttattccg attatatgga tcggaggcat agcggttgag cttacagcag
      901 caatcttagc ggtagtagga gtttacgagc tgttccggat gaaaggattg acactcttaa
      961 gttttgaagg agttttatcc gccgttggtg cagtgttact tgttttgcca aaagaaagat
     1021 ggtttttctt tcttccagag aatgtaagta catttatgtt attttatctt atagttatga
     1081 ttcttttagg aacatcagtt atttctaaaa atacgtatac gattgatgaa gcaggttttc
     1141 ctgtgcttgt cagcttgtat gtgggaatag gtttccagaa ttttgtcaat gcacgaacag
     1201 aaagcttggc tgttttgata tttggtctat ttattgtttg ggcaactgat atcggagcat
     1261 atatggttgg tcgacgttat ggtcagcata agttaagtcc tgatatttcg cccaacaaaa
     1321 cgattgaagg tgcgctcggt ggtatcggta gtgctgttgt agtcgcattt ctttatttat
     1381 tgctataccc agcaaaagaa ctattcaatc atggtatgtt tgtcatgctt ctgatgacga
     1441 ttattttttc agcagtcgga caatttggtg atttggtcga atctgcaatc aaacgtcatt
     1501 atgatgtgaa agactcggga aatatcttac caggccatgg tggaatctta gaccgtttcg
     1561 acagtttgct gtttgtattt cctatcatgc atttatttgg cattatttag taagtatacc
     1621 tgcgtttctt tgtgaatttc ataaaagacg caggttttta tttttcatta tattgatact
     1681 attggtgtct ttggtatact atggtaaaat tatagtgttt tatcgttgtt ttataaaaaa
     1741 cacaaaaaac aagtaaagga gaaaaaagct atgaaaacga ttctgacatt tatcatcgtt
     1801 tttggtatat tagtgattgt tcatgagttt ggtcatttct tctttgcgaa acgatcagga
     1861 atcctcgtcc gcgaatttgc tatcggtatg ggtccgaaaa tttatgggca tcaagcaaaa
     1921 gacgggacaa catatacgct tcgcctatta cctattggcg gttatgttcg aatggcaggc
     1981 aatggggatg atgaaacaga aatggcacca ggaatgcctc tttctctttt actaaattct
     2041 gacggcatcg tagagaagat aaatttaagt aagaaaatcc aattgacaaa tgctatcccg
     2101 atggaattga gccgttatga tttagaagat gagctgacta tcactggtta tgtgaatgga
     2161 gacgaaacag aagtagtaac ctaccctgtt gatcacgatg cgacgattat tgaaaacgac
     2221 ggaacagaaa tcagaattgc gccaaaagac gtacagttcc aatcggctaa attgtggcag
     2281 cgtatgctga ccaactttgc tggacccatg aataacttta ttttggcaat cgtgttattc
     2341 atcattctgg catttatgca aggtggtgtt caagtgacga acactaatcg cgtaggagag
     2401 atcatgccta atggagctgc ggcagaagca ggcttaaaag aaaatgatga ggtagtcagt
     2461 gtggacggaa aagaaatcca ttcatggaat gatctgacaa cagtcattac gaaaaatcca
     2521 ggtaaaacat tagactttaa gatcgaacga gaaggtcagg tgcaatctgt cgacgtgaca
     2581 ccgaaatctg tagagtcaaa tggcgaaaaa gttggccaac ttggtataaa agccccaatg
     2641 aatacaggtt ttatggataa gatcattgga gggacgcgtc aagctttcag cggttcattg
     2701 gaaattttca aagccttagg atcactattt acaggtttca gtttagataa attaggcgga
     2761 cctgtcatga tgtaccaatt gtcttcagaa gcagcaaatc aaggtgtaac aactgttatt
     2821 agtttgatgg cgcttctttc aatgaatctc ggaatcgtca atctgcttcc gattcctgcc
     2881 ttagatggcg ggaaattagt cttgaatatt tttgaaggga ttcgcgggaa accattaagt
     2941 caagaaaaag aaggaatatt gacattagct ggctttggat ttttaatgtt gttgatggtg
     3001 ctagttacat ggaacgatat tcaacgattc tttttctaga aaaagttgac aaatagggta
     3061 taataacaaa cgataactat tttgaggaaa taaaggagta tatagaatga gacaatcaaa
     3121 aatgttgatt ccaacattac gcgaagttcc aaatgatgca gaagtattaa gccatcaaat
     3181 cttgctaaga gctggatata tccgccaagt atcagcgggt atttattcat atctgccatt
     3241 agcaaatcgt gtattggaaa aactgaaacg cattatgcgg gaagaatttg aaaaaatcgg
     3301 agcggtagaa atgctgatgc ctgccatctt gccagcagaa ctttgggaag aatccgggcg
     3361 ttacgaaaca tatggaccaa acttgtatcg tttcaaagac cgcaatgatc gaaaaatgat
     3421 ccttggacca actcacgaag aaacttttac tgatttgatg cgtaatgaaa tcaattcata
     3481 taagaaatta cctttaaatc tttatcaaat ccaacctaaa tatcgtgacg aaaaacgacc
     3541 tcgcttcggt ttgcttcgcg gaagagagtt tatcatgaaa gatgcatatt ctttccatgc
     3601 aacggaagaa agtttggacg agacatataa agattacgaa aaagcctata ccgaagtatt
     3661 caagcgttgt ggcttagaat ttcgctcgat catcggagac ggcggcgcaa tgggcgggaa
     3721 agactcaaag gaattcatgg cgatctcaga aatcggggag gatacgatct gttattcgac
     3781 tgaaagtgat tatgctgcaa acttggagat ggctacaagc tactatgtat caaaaaaatc
     3841 gcatgaaaca cagcttgaat tggagaaagt agctacacct aacgtaaaat caattgacga
     3901 agtagcagat ttcttttctg ttgaacctca aaaaatcatc aagtctgtat tgttcattgc
     3961 ggatgaacaa cctgtccttg ttttggtacg tggagaccat gaagtcaatg acgtaaaact
     4021 gaaaaacttt ttatctgctg actttttaga agaagcaaca gaagaagaag cacaaaaata
     4081 tctaggtgct gagtttggtt ctgtcggacc agtcggtgtt tcagatgacg taaaagtata
     4141 tgcagaccgt tatgtccaag atttagcgaa tgccattact ggagcgaacg aaacaggatt
     4201 ccactataaa aatgtgaatc cagaacgcga tttcactgtg ctttcttatg aagatcttcg
     4261 ttttgtacaa gaaggagatc cttcaccaga caacaacggt gttcttgcct ttactcgagg
     4321 aatcgaaatc ggacatatat tcaaaatcgg cactcgttac agtgaatcta tgggagcaac
     4381 tgtactagac gaaaatggac gagaaaaatt tgtgattatg ggctgttatg gtatcggtgt
     4441 aagtcgttta ttatcagcaa tcgtagaaca acattcagat gaacaaggaa tcaattggcc
     4501 aaaaggaatt gcgccatttg atctgcatat cgtccaaatg aatctaaaag acgaatacca
     4561 aacaagcctg acgaatgaac tagaagaagc gatgacaaaa gctggctatg aagtactggt
     4621 tgatgacaga aatgaacgcg caggagtgaa attcgcggat tctgatttga ttggctgtcc
     4681 aatcagaatc actgtcggta aaaaagcagt ggatggaatc gtagaagtga aaatcaagaa
     4741 aactggcgaa atggttgaag tacgtaaaga agaattggcg aatactttac caatcctctt
     4801 gaaccaaggc gaataataag cgttaaaaca cagaaaataa aaatagctga atcagctgtt
     4861 tttgacaatc tgatgattcg cttttaaaat tggaactgcg atttgaatcg cagttccaat
     4921 tttttaatgt aaaactcaga aaaaacgagt atactaaaag gtactgaaaa agaagaggat
     4981 aagatgcgat caattgcatt gtttctcatc agaaagggcg tatatctttg tcagaaaaac
     5041 gagatttatt tgaaaaactg ttggaacaaa tccaactaga ggaagcagaa aaaaatcatc
     5101 cactgcttac tgctggtgaa atggatagtg tagtggtcca tcgtaaatcg cgtttatggg
     5161 aatttacgct acatttttcc aaaattttgc ctattatgct atatcggtca ttgactcagc
     5221 atctgactat cgcttttaaa gatattgcac aagtcaaact gaatatctta gcagatgacc
     5281 agacattcga tgaacagctc ttgcaagatt actgggccca agctttggaa aatcagcaat
     5341 gcgatacacc actagcacag caagtattga aaacgcaggt acctgtgata aaagatcgta
     5401 aagtcatctt gccaatcgac agtacaggag ctatttctta tttgaagcaa caatacttgc
     5461 cattagtaga agagttgttc gtcagttacg gattcccaaa atttcgtatc gaaccagaag
     5521 tggatgagca gcaagcggaa cgtgtattga aactttttga agaacgcaaa caagaacagg
     5581 cagaagcctt tatgaagcaa gcagctgaaa gtctagttgt ccacgaacaa aagaaaaagg
     5641 aaagaaaaga gcaatcgcca gctcttgaag gacccatcca gctaggacga aatattccag
     5701 ccgatgaacc aacgacacca atgatcagta tcgttgaaga agaacgaaga gtcacacttg
     5761 aggggtacgt attcgacaaa gaagtcagag aactacgttc aaaacgcaag atcttgactt
     5821 tgaaaatcac agattatact tcatcattta tcgtcaaaaa attctcgaac ggcgaaaaag
     5881 atgaacaagt atttgatgcg atcagtgtcg gtagctggtt aaaggtacga ggaagtattc
     5941 aagaagatac gtttgtccgt gatttggtca tgaatgcgca agatatcata gaagtcaaac
     6001 atacacctcg caaagattat gctcctgaag gggaaaaacg agtagagctt catgttcata
     6061 gcaatatgag tacgatggat gcaacaaaca gcatctctga tcttgtggca caagcaggaa
     6121 aatggggaca ccgagctatc gccattacag accatggtgg tgcgcaagcc tttccggaag
     6181 cacatagtgc tggaaaaaaa gcaggtgtga aaatcttata cggcgtggaa gcgaatgtcg
     6241 tagatgatgg tgtcccaatt gcttataatg atgcacatga agcattgagt gaagccacat
     6301 acgtcgtatt tgacgtggaa acgacaggat tgtctgcagt atatgacacg atcatcgagc
     6361 tagccgcagt caaaatgtat aaaggaaatg tgatcgaaag ctttgatgaa tttatcgatc
     6421 caggacatcc attgtcacga acaacggtag atctgactgg tatcacggat gaaatggttc
     6481 gagggtcaaa gtcggaagaa gaagtattgc ggatgttcct tgaattttca aaagatacaa
     6541 ttttggtagc ccacaacgcg gcttttgata tggggttctt gaatactagc tacgcaaggt
     6601 atggtattcc tgaagcggcc aatccagtca ttgatacgtt ggaattagct agatatctgt
     6661 atcctcaatt caaacgtttc ggattaggtg tgttatctaa aaagtttggt gttagcttgg
     6721 aacagcatca ccgagcaatc tatgatgctg aagcaactgg tcacttagca tggatctttg
     6781 tgaaagaggc aatggacaat cataacatgc tttatcatga tcagctaaat gagcatatcg
     6841 gagaaggaga ttcttacaaa agggctcgac ctttccatgt aacgatttta gcaaaaaatc
     6901 aggcaggact gaaagatttg ttcaaactga tttcaatgtc gaatgtcgaa tacttcgaac
     6961 gcgtcccacg aataccacgc tcccaattga aaaagatgcg tgaaaatcta ttgatcggct
     7021 cagcttgtga taagggagaa atattcgaag ccatgatgca aaaaggggta gaagaggcaa
     7081 gaaaccgagc aaaattctat gattatattg aagttatgcc aaaagcggtc tatgcgcctt
     7141 tgatcgagca agaattggta aaaaatgaac atgatttgga agaaattatc caaaatttgg
     7201 tagaaatcgg aaaaagtttg gataaaatcg ttgttgcaac aggtaatgta cattatctga
     7261 acgaagaaga tgccatttac cgaaaaattt tgatcaattc tatgggcgga gcgaatccgt
     7321 tgaatcgtca tagtttgccg gatgtccatt tccgaacaac cgatgagatg ctaactgcat
     7381 ttcacttttt aggggaagaa acagcgaaag agatcgtagt agaaaatacg aataaaatcg
     7441 cagatatctg cgaagaagtg attccagtca aagatgaact ttatacaccg aagattccag
     7501 gttcagaaga tgaaatatca gaattgagtt acacaaaagc aaaacaaatg tacggagatc
     7561 cgttacctga gatcattcaa aaacgattag aaaaagagtt gaattctatt aatggtaatg
     7621 gcttctcggt tatttatctg atcgcccaaa aactagtgca taaaagtaat gaagatggct
     7681 atctagtagg ttcacgtggc tctgttggct ctagctttgt tgcgacgatg acaggaatca
     7741 ctgaagttaa tccattagcc cctcattatt attgtccaga gtgccaatat tccgagtttt
     7801 ttgaagatgg tacgtatggt tctggatttg acatgccaga aaaacaatgt ccaaaatgtg
     7861 gtgcacgctt aaacaaagac ggtcatgata ttccatttga gacattttta ggattccatg
     7921 gagacaaagt gcccgatatt gatttgaact tctcaggtga ttatcaagca gaagcccata
     7981 actatacgaa agtattgttt ggcgaagact atgtttaccg tgccggaacg attggtacag
     8041 tcgccgacaa aacagcatat ggctatgtaa aaggatacga aagggacaat aatctgcagt
     8101 ttcgaagtgc agaagtcgac agattagcaa aaggcgctac tggagtcaaa cggacaaccg
     8161 gccagcatcc aggggggatc atcgttattc ccgattatat ggatgtctat gattttacgc
     8221 cgatccaata tccagcagac gatcaaaatt cagaatggaa aacgactcat tttgatttcc
     8281 actcgattca cgataatgta ttgaaattag atattctagg gcatgatgac ccaactgtta
     8341 ttcggatgct tcaagattta tcagggatcg acccacaaac gatccctacg gatgacccgg
     8401 aagtgatgcg gatatttgcc ggtcctgaag tacttggagt aagtcaggaa caaatttatt
     8461 ccaaaacagg gacattaggt attccagaat tcggcactcg ttttgttcga gggatgttag
     8521 aagaaacgca tcctacaact tttgcagaac tactgcaaat ttccggacta tctcatggta
     8581 cagacgtatg gttaggaaat gcggaagaat tgattcgacg aggagatgcg acactggcgg
     8641 aagtaatcgg ctgtcgtgat gatattatgg tttatttgat ccatgctgga ttagatagcg
     8701 ggatggcatt taaaatcatg gaaactgttc gtaaaggaca atggaacaag atccctgatg
     8761 aattgcgaga aacctatcta tcggcgatga aagaaaataa tgtgcccgac tggtatatcg
     8821 attcttgttc aaaaatcaaa tatatgtttc cgaaagccca tgctgcagct tacgtattga
     8881 tggctcttcg tgtcgcttat ttcaaggttt atttccctat tttgtattac tgtgcatact
     8941 tttctgtacg tgcagacgac tttgatctag tctccatgtg caaaggaaaa gatgctgtga
     9001 aacaagcaat gaaagaaatc acggacaagg gattagatgc ttccgtaaaa gaaaagaatc
     9061 aactgacagt gctggagtta gccaatgaaa tgctggaacg aggattcaaa tttggaatga
     9121 ttgatttgta taaatcggat gccgttaact ttgttattga aggtgatacg ttgatcgcac
     9181 catttagagc tgtcccaagt ttgggaacca acgtggcgaa acaaatcgtt gaagcaagaa
     9241 aagacggtcc atttttatcc aaagaagatc ttgccacccg cggtaaagtt tcaaaaacat
     9301 tgatcgaata tatgaacgac aatggcgtat tgaaagatct accagatgaa aatcaattat
     9361 cgttattcga tatgctataa gcatctgttt tcctgtctgc ttgtaatttt aagcagagta
     9421 tggtatagtt cttataggta atgatactaa ctgtgagtga gcggattttt cgctcactct
     9481 ttttaatgga attacgcact taatttttaa ggaggcgaaa cttttgagta gcgtcgttga
     9541 aacagtcaca gaaatggtga caccgatttt agatgaacaa aattttgaac ttgtcgaagt
     9601 cgaatttgta aaagaaggaa aaagctggtt cttacgagta tttattgaca aagaaggcgg
     9661 tatcgatatc gaagaatgcg cctttgtcag tgagaaactg agtgaaaaac ttgatgcagc
     9721 agatccagat ccgattcctc aagcttattt cctggaggta tcctccccgg gagcagagcg
     9781 gccattgaaa aaagaaagcg actatgaaaa ggcacttggt gattatgtcc atgtctcctt
     9841 ataccaacca gtagatggcg aaaaacaata tgaaggattt cttcaatcat ttgatgctga
     9901 acagcttaca ttgaaaatac gcataaaaac acgagaaaaa gaattgactt ttgaccgaaa
     9961 aaatattgca aaagctcgct tagctatcca attttaatca cggagaggaa tcagaaaaaa
    10021 atgagtaaag aaatgttaaa tgcgttagac gctttagaag ctgaaaaagg gatctcaaaa
    10081 gaaatcgtga tcgatgcatt agaagcagca ttggtttctg catacaaacg tcactatggc
    10141 caagcacaaa acgtcgaagt ggaatttgat cagaaaaaag gaaagatcca tgtctatgcg
    10201 gtaaaagaag taacggaaga agtgatggat tcacagttgg aagtctcatt gaaagatgca
    10261 cttttaatca atccagcata tgagatcggt gatacgatcc gttttgaagt aacaccaaaa
    10321 gattttggac ggatcgctgc gcaaacggct aaacaagtta ttttacagcg tgtacgtgaa
    10381 gcagaaagaa cgattattta taacgaattc agtgcttatg aaaaagacat catgcaagga
    10441 atcgtcgaac gccaggataa acgttatatt tatgtcaatc ttggtaaaat tgaggcagtt
    10501 ctttctaaac aagatcaaat gccaaatgaa ttttatcaac cacatgatcg aatcaaagtt
    10561 tatgtttccc gagtagaaaa tacgtctaaa ggtccgcaag tatttgttag ccgcagccat
    10621 ccagacctat tgcgtcgctt atttgaacaa gaagtaccag aagtctatga tggaatcgtt
    10681 gaaattgtca gcatcgcccg tgaagctggc gatcgttcaa aagtggcagt tcgctcaaat
    10741 gatccaaata tcgatgcagt cggtacatgt gtcgggccaa agggacaacg agttcaagca
    10801 atcgtcaatg aattaaaagg cgaaaacatg gatatcgtcg aatggaatga agatccagct
    10861 gtattcatcg caaatgcatt gaatcctgca caagtcatgg atgtgatctt cgatgagaca
    10921 aattcaaagg cctgcacagt tgtcgttcca gactaccaat tatcgctagc aatcggtaaa
    10981 cgcggacaaa atgcacgttt agctgctaaa ttgactaacc ataaaatcga tatcaaatca
    11041 gaatctgaca tgacggaatt ttatgaaaat caagaacaac aaaaagaaac agaagaactg
    11101 catgatgaag caatcgttca gtcagattta acagacgatg aatatgaaac aattgcattc
    11161 aacaatgaaa cggtcgaaga aaaaccagaa gcttaacttt agtaaggagg caaagagatg
    11221 aaacaaagga aaattccttt acgcaaatcc gtggtttcag gtgaaatgaa acctaaaaaa
    11281 gagatggtcc gaatcacccg ttcaaaagaa ggggaagtat cgatcgatcc aactggaaaa
    11341 atgcctggac gaggagcgta tgtctcactt gagccggaag aagtacaaca agcttgggat
    11401 aaaaaaattc tcgatcgagt actcgaaaca acattaacag atgagtttta tcaagaactt
    11461 cttgactatg tcactcacca aaaagcacgt aaagagttat ttggaaaatg aatacagtta
    11521 atcggcaaaa agccatgaat ctcatcggtc tagcgatgcg cgcgggaaaa ctaatcacgg
    11581 gtgaagaact gaccattgct gaaatccgca aacaaaaagc aaaattggtg tttgtggcaa
    11641 ccgatgcaag tgagaataca agaaaaaaga taaaagataa gagttcatat tatgaagttc
    11701 cttgctttga gctattttct gaagcagaaa tcacgcagat gatcggaaaa cctcgcaagg
    11761 tattcggaat aatggatgcc ggatttgcga agaagaccaa ggagctaatt gaaggttagg
    11821 aaggtgattg catgggcaac aaaagaatct atgaattagc aaaagaactc aaaaaatcta
    11881 gtaaagacgt cgtggaaaaa gcacaacaac ttggcatcga tgtgaaaaac catatgggtg
    11941 cgattactag cagtgatgag aagaaattgc aacaagcgtt caaaaaccca agcacgaaac
    12001 aacaagctgc acaacaagca agcagaaaac cagccaatca acagccgaac gatcaacgta
    12061 aaaaagaaac aacgaacaat caacaaaaaa ataaaaataa ccgcagttat caagatcgcg
    12121 gtcaagggag cggtcaagtg aatcaaggaa aaaaaccaac aacaaaccaa aataatacgg
    12181 gaaataccag cagccaaaat cgtcaaggaa cgagccaagg cggcaatcaa aaccgtacta
    12241 acaataacaa caaaccaaac aataacaatc gcggcaaatt taataataat aaccgtaatc
    12301 gttataataa aaaaggtaaa aaaggcaaac agcaacaatc aactaaacca gctgtaccac
    12361 cacgcaaatt ccgtgaattg ccagatgtat tagagtatac tgaaggtatg aacgtagcag
    12421 atattgcgaa aaaaattcat cgtgagccag cagaaatcat taaaaaatta tttatgcttg
    12481 gtgtcatggt caatcaaaac caagcactgg ataaagatac gattgaactg ttagcgacgg
    12541 actatggcat ggaaccacaa gaaaaagtcc aagttgacat tgctgatatc gataaattct
    12601 tcgaggcaga agaagtcgat ccagataaat tagtctcacg tccgccagta gtaacgatta
    12661 tgggacacgt agaccacggg aaaacaacct tattggatac attgcgccat tcacgtgtaa
    12721 caagcggcga agccggcgga atcacacagc atatcggtgc ctaccagatc gatattgatg
    12781 gtaaaccaat cactttcttg gatacaccag gacatgcggc ctttacaagt atgcgtgcac
    12841 gtggagcaag tatcacagat atcacgatct tagttgttgc tgcagatgat ggcgtcatgc
    12901 cacaaacagt tgaagcaatc aaccatgcca aagctgcagg cgttccaatc atcgtcgctg
    12961 taaataaaat tgataaacca ggtgcaaatc ctcagcatgt tatgcaagaa ttaagtgagt
    13021 atgaattaat tcctgaagca tggggtggag aaacgatttt tgttgagatc tcagcgaaat
    13081 tcggccaaaa catcgaagaa ttgctggaaa tgatcctgtt agtcgcagaa gtagaagatt
    13141 taaaagcaga tccaacacaa cgcgcaatcg gaacagtgat cgaagcacgt cttgataaag
    13201 gtaaaggtcc tgtgtcaacc ttacttgtcc aagaaggaac acttcacgtt ggtgacccaa
    13261 tcgttgtcgg taatacttac ggacgtgtcc gtgtaatgac aaacgatctt ggccgtcgcg
    13321 ataaagaagc aggacctgca acgccagtag aaatcactgg cttgaatgat gtacctcaag
    13381 caggtgaccg tttcgtagtc ttcgaagacg aaaagacagc acgtgcagcg ggtgaagaac
    13441 gcgcaaaacg tgcattattg gaaaaccgtg ctgccacaag ccgtgtgact ttggacaact
    13501 tatttgaaag cctgaaagaa ggcgaattga aagaagttaa cgtaatcatc aaagcagatg
    13561 tacaaggttc agcagaagca ctggctgcat cattgaagaa gattgatgtg gaaggtgtcc
    13621 gtgtaaaaat cgtccattca gctgtcggag caatcaatga aagtgatgta accttagcag
    13681 cagccagcaa cgctattatc atcggtttca acgttcgtcc tacaccgcag gcaaaagtgc
    13741 aagctgatac tgaagaagtc gatattcgtc ttcaccgtat catctataaa gccatcgaag
    13801 aaatcgaaac tgcgatgaaa gggatgctag accctgaatt tgaagaaaaa atcaccggtc
    13861 aaatgatcgt tcgtgaaacc ttcaaagttt ctaaagttgg tacgattgca ggtgcctatg
    13921 taacagaagg atatattcgt agagatagcg gtgtccgtgt aatccgtgac ggaatcgtaa
    13981 tctatgaagg ccaacttgca agtctgaaac gattcaaaga tgacgtgaaa gaagtcaaaa
    14041 tgggttatga atgtggtgcg atgattgaaa aattcaatga catcaaagta gatgacgtaa
    14101 ttgaaggatt tatcatggaa gaagtcaaaa atgactaaaa actgataaaa ggaggccaat
    14161 cattatggct aactaccgtg atcgccgagt cggtcaagaa atcttaaaag aagtcaatga
    14221 tattttgcgc aaaaaggtcc gtgaccctcg tgtggagaac gtaacgatca cagatgtgaa
    14281 agttacgggg gacttacagc aagcaacgat ctattacagc attttatctg acttagcatc
    14341 agataagaaa aaagcacaag atggattgaa taaagcatca ggattgattc gtcgagagtt
    14401 agggcacaat ctaagtattt ataagacacc tgaattgttc tttgaacttg atgaatcagt
    14461 tgtctatggg aaccatatcg atgaattgct tcgcgacttg aacaaagact aatcaaaaaa
    14521 tcccgcaaat cctgtgaaat caggggttgc ggg
//
LOCUS       DACBZK010000067        14496 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.070, whole genome shotgun sequence.
ACCESSION   DACBZK010000067 DACBZK010000000
VERSION     DACBZK010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14496
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.070"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            136..456
                     /locus_tag="IVD66_002150"
     CDS             136..456
                     /locus_tag="IVD66_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146350.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            908..1108
                     /locus_tag="IVD66_002151"
     CDS             908..1108
                     /locus_tag="IVD66_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP6146351.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            1255..4044
                     /locus_tag="IVD66_002152"
     CDS             1255..4044
                     /locus_tag="IVD66_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP6146352.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            4091..4618
                     /locus_tag="IVD66_002153"
     CDS             4091..4618
                     /locus_tag="IVD66_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP6146353.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            4639..5829
                     /locus_tag="IVD66_002154"
     CDS             4639..5829
                     /locus_tag="IVD66_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP6146354.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            5869..7167
                     /gene="asnS"
                     /locus_tag="IVD66_002155"
     CDS             5869..7167
                     /gene="asnS"
                     /locus_tag="IVD66_002155"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HAP6146355.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            8343..9017
                     /locus_tag="IVD66_002156"
     CDS             8343..9017
                     /locus_tag="IVD66_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP6146356.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDNIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            9014..9355
                     /locus_tag="IVD66_002157"
     CDS             9014..9355
                     /locus_tag="IVD66_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146357.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            9385..9744
                     /locus_tag="IVD66_002158"
     CDS             9385..9744
                     /locus_tag="IVD66_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HAP6146358.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            9948..10127
                     /locus_tag="IVD66_002159"
                     /pseudo
     CDS             9948..10127
                     /locus_tag="IVD66_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308695.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
     gene            10269..12353
                     /gene="cadA"
                     /locus_tag="IVD66_002160"
     CDS             10269..12353
                     /gene="cadA"
                     /locus_tag="IVD66_002160"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAP6146359.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
     gene            12644..14110
                     /locus_tag="IVD66_002161"
     CDS             12644..14110
                     /locus_tag="IVD66_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6146360.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
BASE COUNT         4800 a         2510 c         3101 g         4085 t
ORIGIN      
        1 agaggttgtg acgtggtcac gacctctttt tgacgattat gatacaaaaa acatcattta
       61 tgaacaaaat gtgaataacg ggcgttcttg agatatgatt ttaattggga aaaacttatc
      121 gataaggagg tctttatgaa aaaaagactg ttatggtgtt tgctgtttct atccctaagt
      181 ttaacaagtc agccagtttt tgctgaagaa acacagcggt ctcctattac aggcacacgt
      241 ctgtacaaaa atgtttatgt acagacaaca gatcttgatt ctgcgattcc tgaaacagaa
      301 gaacggtctt tgcagccaag atttggttac ttttggtact gtccgacctg tgattatgaa
      361 agttgctggc atttcttaca ttctacagct gcagcttttg cttttactca tactcagaaa
      421 tatgatggac atcatcctgt tatttatgag gtatagatat gagcaaaaaa gaaaaactaa
      481 tctcgttgat cgtattggtt tgccttgttc ttctggtaac tgtcataggc tatcagaaat
      541 accatgagaa catcagacct actaaagaat cttccccagc ctcgaccgtt gaaacagaac
      601 cgataagtag tcagaaagaa taattttttt agtttaaaga agaacatcag agcaaaaaaa
      661 caccaactga acaatatgtc gtttatttta aaaaaagttc ggtttttcac tttatgtaat
      721 cgctgagaaa acttttttta ataaaaaaag tcgaaaaact ctagcttttt tgtaaacggt
      781 atgatatact ataggagtag tttttgttcg gtaatctgtg gtagcttgtt tcaaataaac
      841 atcttccaga tatacaccat tcaagtaatt gcaaaatatg tgttgataca caaggaggat
      901 ttttattatg gaaacaggta cagtaaaatg gtttaactca gaaaaaggat ttggattcat
      961 cactgcagaa aacggaaacg atgtattcgt tcatttctca gctatccaag gcgacggatt
     1021 caaaacttta gaagaaggcc aagcagtaac tttcgatgtt gaagaaggcc aacgcggacc
     1081 tcaagcaaca aacgttacta aagcttaatt aacctatact aaaaaataaa cgcccagaca
     1141 tttgcgtgtc tgggcgtttt tgtctatttt ctttaaaaag cgatgagagt atttttctgc
     1201 actttgtagt ataatttcaa aagaacatta gaggcaggag aagaggaaga tattttgaaa
     1261 ccaagaactt atgcagtcgt tgatatcgaa acgactggga cgaatccaaa agaagatcgg
     1321 atcatccaat ttggctgcgt catgattgaa tcaggtcgga tcacttcacg tttttcgatc
     1381 gatattcatc cagggcggaa gatttcaaaa caaatccagc atttaacagg gatcacgaat
     1441 caacgcgtcc aaaaagcgcc ttatttcgaa gatgtcgccc aaacgattta caatcttttg
     1501 gcagacacca tatttgtcgc gcataatatt tattttgatt ataatttttt gaaccatgaa
     1561 ctcatgcgat gcggacttcc tagtttgaag ataccaggca tcgatacagt agaacttgca
     1621 caaattttct tgccgacgga accaagcttt cgcttagctg atttgtcaga aagccttgga
     1681 tttattcatg agaatcctca tcaggcagat agtgatgccg aagtgacggg tcaacttctt
     1741 ttgctgatcg aagaacggat gagaaaattg ccaatcatca cgttagagca gattgcgcga
     1801 ttaagtagac acacaggtat ggatacgagt cgtttcattt atcatgtgat tgaagaaatg
     1861 aaagaaaaac cagagccact tgatccctca ttagaaatcg tcgatgggct agctttgcag
     1921 aaaaaagaag tggaactatt cacatccgtc cattatggcg agcggacata tccaagaaaa
     1981 aaacaagcaa aagaaaaaat gtttggtaaa acactgatgt atcgaaaaga acagaacaga
     2041 ctgatgaatg cggtctacga ccatttcaca aaagatgaat caaaagattt gatgatcgaa
     2101 gcagctacag gaatgggtaa aacaatcggt tatctgctgc cattgagtta tttggctaca
     2161 cctgaaaaac ccgctgtcat cagtaccgtt tcgctagttt tgcagcagca gatcatagaa
     2221 aaagacattc cattgctgaa tcaattgcta gatcagccca tacaacctgt aattatcaaa
     2281 agctatcgcc actatattga tttgcagcgt tttaaaggca cacttgtgga accgccagaa
     2341 caaaaacaat atgctttgta tcaaatggcg gtcttagttt ggctgacgca aacgaagact
     2401 ggtgatttgg atgaattaca tttaacaaat ttgaaccatt cattctttgc agatatcgcg
     2461 cacagaggta ttggattttt agcaagaaat cagtcatttt acgaacaaga ctttgttcgt
     2521 ttcttgcaaa agaaaatcag gcaaagtaat tttttgattg tcaatcatgc gtttttagta
     2581 caagaaacac agcgaaaaga accattgctt ccagctagtc catttttgtt gatcgatgaa
     2641 gtacatcatt tgccggaaat cgctgaaaaa gtaaatgaca aacgattaag tattaactat
     2701 ttccataaac aaatccagca attagaagaa ccaaatcagc tgtttgaccg aatacaaagc
     2761 tatttaccga aagaacatga agccttacgc tggttatcga tttatcgaga agaactttct
     2821 gcgctatgcg aagcacagat ttgtatggca gaaggattaa tgagtttagt gagcggcaag
     2881 caacctaacg gacagtatcc agaagaagtc atgatgacaa aagagatgtt ggatcagctg
     2941 ccactggaat ctgggacagc cattgatcac ctgcagcttt tttatcagga gatccagcag
     3001 ctacagtcac aaatgcgtct gacttttgag attatccaag aaagctggac aaaccagatg
     3061 cggatcgatt tagcaagttt atatagccta tttgatcaat tagacaagca atacttgctg
     3121 atggatcaat ggctggaaga ctggcgagat catttgatcc attggttcgt tcctgggaac
     3181 acagcgcagc agatgatttt tcatctccat gattttcaag cggctatgtt gccgtcgact
     3241 gtttggtatc ctcgatatga tcgtattctt tatattggag gaacgctgaa gatcggccct
     3301 aatcgacact atctctctaa gaggcttggc attgaagcag cacctcttaa agtgattgcc
     3361 tctccttatg attatgagaa acaggcaagg atctatgtgc caaaagaggc acctgccgtc
     3421 catcaagtca gcaatcaagc atatatcgat tatttagaga cagcacttac aggtctgatc
     3481 gaacaagaag atcggccaat acttgtgtta ttcacttctc atgatgtttt gcagaaggtc
     3541 tatcagaaaa tgcatctgtc tatgctagaa aaaggacgag aaatactagc tcaagggttt
     3601 ggtggaagcc gggagaagct tttgaaacgc ttcattttgt cagaaaaaag cgtattgttt
     3661 ggcgctgaca gcttttggga aggtgtagat ttgcctggag atgctttgca gatcgttgta
     3721 gtcacacgtt tacccttcga taatccgctt cgcccgatgg tcaaagctag gaacgcttat
     3781 ttagaatcag aggggatcaa tcctttttac caggaatccg tacctaaagc agctttgaag
     3841 ttacgccaag cattaggtcg cttgataagg acggagacag atcgtggcgt attgcttatt
     3901 ttggatcgaa gactagtcac tgcaaaatat ggcgcacgga tcatccatgc attaccgaaa
     3961 aaagtaccga tcaaagagct agctatggag gaaatctatc aggatatcca tgaattctta
     4021 aagaaaaatg aagaaggaag ttagaggagc tgtctttttt cataattaaa atctgctata
     4081 atgaaaagga atgaagataa aggagcgacg acccttgaag aaaaaacaga caaaggaaaa
     4141 aacgattaat cgcgtgttac ttggcttgat cgtattttta ttagcggtca tcgtgatcag
     4201 ctcgattttt tacttgcgtt ccagtcgtcc ggcggtgcag gcgaagaaag aagcagtaga
     4261 aatcgcaaag aaatatgcaa atcttgagga aaccgatcat ttttattggt ttactcgaaa
     4321 gaagacatac ttttcactga caggtacaaa tgataaagga aaagaaatcg ccgttatcat
     4381 tcctaaatct ggtgaaaaag taaaagtatt ggatcaaaca aagggactga ctgaaaacga
     4441 agcaaaacag acaattgctg cggcccatcc tgaaatccaa atcgaaaaag ctgctttagg
     4501 gatgtatgat gatcagcctg tgtgggaagt agtaggaaaa gaaacaaatg ggaaactgaa
     4561 ttattacctg attggctttg aatctggaga tgaagtcaag acaatcaagg gaatttaaaa
     4621 ggtaaaggaa tgaatgggat ggagttatca aaaagaacaa aacgattaga accgtctgtc
     4681 actttggcag ctgcggcaaa ggccaaggca ttaaaagcaa aaggcagaga tgtgctgagt
     4741 ttgactgtgg gagaaccgga ttttgcgaca ccagaaaaca tccaagaagc agcaatcgaa
     4801 gcaatccgca atgggaaagc tagctattat acaccaacag caggaatccc agagcttcga
     4861 caggcaatcg ttgattatct gaagaaaaac tatggacttg tctatgaacc ttcacaaaca
     4921 gtcgtaacag acggagcgaa atttgctttg tatacccttt tccaaacgat ccttgacccg
     4981 caagatgaag tcatcattcc tgtgccttac tgggtcagtt acggtgagca agtaaaactg
     5041 gcagaaggac ttcctgtctt tgtgaaaggg gaagaatcca atagctggaa agttactgtt
     5101 gaacagctag aacaagcacg ttcagaaaaa acaaaagccg taatcatcaa ttctccatcg
     5161 aatccgactg gaatgattta tagcaagaat gaactgcagg caatcggtga atgggcagta
     5221 aaaaatgata ttttgatagt tgctgatgat atttatggcc gtttagttta taatggcaat
     5281 gagtttactc caattgcaac gatttcagaa gcaatcaaaa atcagaccat catcatcaac
     5341 ggcgtgtcta aaacatatgc gatgacaggc tggcgcattg gttatgcggt gggaaatcct
     5401 gtgatcatca atggaatgat cgctgttgct tcccaatcaa ctagcaatcc gacagcagtc
     5461 agtcaatatg cagctgttga agcattgaaa ggtgagcaag atacagtaga agaaatgcgg
     5521 aacgcctttg aagaacgcct gaatacgtta tatccgcttg tggcagaact gccgggtgtt
     5581 tctcttgaaa agccgcaagg agctttctat ctttttccta atgtaaaaga aacgctacgc
     5641 atgtgtaagt atgaaaatgt cacacaatgg gtagaagatc ttttagaaga aacaggggta
     5701 gcgcttgtga ctggcgaagg ctttggggca ccagaaaatg tccgcatgag ttatgccact
     5761 gatcgcgcta cgttagaaga agcggtacgc agaatcaagc aatttattga gagtaaaagt
     5821 caaaattaat cctgaagaaa ttcaaggaat ataaaaggag agtcatacgt ggaacaaatt
     5881 caaatcatcg attcgaaaaa ccatgtggga gaaacagtaa caatcggcgc ttgggtcgca
     5941 aataagcgat caagcggaaa aatcgcattt ttacaattaa gagacggaac agcctttttc
     6001 caaggtgtag ttgtaaaaag cgaagtgtcg gaagaagttt tccaaacagc taaaaatcta
     6061 caccaagaaa catccgtgtt agtaactgga gaaatccgtg aagacagtcg ttcaaaattt
     6121 ggttatgaaa tcggaattac aaatgtggaa gtggtaagcg agagccacga ttatccgatc
     6181 acaccaaaag aacacggaac agatttcttg atggatcatc gtcatttatg gctgcgttct
     6241 tcaagacaac atgcgattat gcagatcaga aatgaaatca ttcgtgcaac gtatgaattc
     6301 tttaatcaac atcattttgt caaaatcgat ccgccgatct tgactggttc tgcaccagaa
     6361 ggcactacgg atctattcga aacaaattac tttgatcaaa aagcttattt atctcaaagt
     6421 ggccaattat acatggaagc tgctgctatg gctttcggaa aagtcttttc attcggtccg
     6481 actttccgtg ctgaaaaatc aaaaacacga cgtcatttga tcgaattctg gatgatcgaa
     6541 ccagaaatgg ctttcactca tcaagaagaa agtttagaag tacaggaaca atatgtagca
     6601 ttcttagtac aaaatgtttt agatcattgc gaatatgcat tagatgtact aggacgagac
     6661 aaagaagtct taaaaactta tacaaaattg ccattccctc gtattactta cgatgatgca
     6721 atcgaattac tgaagaaaaa tggatttgat gacatcgaat ggggcgaaga ctttggttca
     6781 cctcatgaaa cgttcattgc gaattcattc gaacagcctg tctttatcct aaactatcca
     6841 aaagccatca agccattcta catgaaacca catccaacaa gagaagacgt ggtaatttgt
     6901 gcagatatga tcgcaccaga aggttacggt gaaattattg gcggaagcga acgggcaaca
     6961 gactatgatt tcttgctaga acaaatccgt aatcacggtt tggatgaaaa agaatattca
     7021 tggtatcttg atctacgtaa atacggttct gttccgcact ctggttttgg tctaggcctt
     7081 gaacgaacag tcacttggat tgctggtatc gaccatgtac gtgaagctat tccattccca
     7141 cgtttgttga accgaattta tccataagag gtgatgaaaa agctgttctg catcaagtaa
     7201 ttagaacagc caagcaaaaa cagctgttca tgtttttgaa ttggcgggac ttattaccgc
     7261 agatgtaagc ttttgaatac cgtttagtgg agaggttgtg aaaaagctgt ttagtttcga
     7321 gtattaagaa aaattttgtg gaaatggctt tccacatttt tgcataaatt tggcttaata
     7381 ccgagaaact ggcttttgaa caccgtttaa ggaagaggtt gtgaaatcag tgccttgacc
     7441 tgagtattag agaaacaaaa cggaaaaata gcttctcata ttttaccgtt tttttagcta
     7501 atatcgaggg tcagctgatt gaacaccgtt tatatcaaga ggttgtgcgc ctgccgttca
     7561 gctccgagtc acaaggagta atttcaaaaa acagtttttc atgtttgatt actattgtga
     7621 cttgtgaccg aggagttggc cggagagcaa cgtttattta aaaaaaagaa ctgcgaactc
     7681 tcgcagttct ttttttaaaa tacgggataa aggaagtttc cagcagacaa gagaagaaag
     7741 caaaagaaat tgctatttga ttcacaaggt tctataacga aatcgcaatc aatcaaacat
     7801 atacaaagaa ggttattcaa atggaaatct gatttgatga tgcttctgct gttgaaataa
     7861 agcagcatct agtacctgaa aacaaactaa tagtaacatt cgaagatgga gtaggtccgt
     7921 attttcagca tgcaatgatc catatgtaag tttaattcat ccttgaaatc atcggaccag
     7981 ataaagttat gaccaatcta tcccaagcaa tctagaagag atattagtaa aagaacattt
     8041 actggaagtc ttagatgagc ctataaatat atgttctgat ggcgtcatca gtggtctgat
     8101 tgacggaagc ttaggtgtga tcgatttctc tggaccaaac aacgaaggaa tcaaggggaa
     8161 tccggcacgt taagaaaaaa agtataaaaa actagacact tgatgagcgt tcattcaatt
     8221 gattgaaggg actaggctgg tgtcattttt tatacatata ttttctcttt cgtcttgata
     8281 gggcttatgg gataatataa ggaagaaaat catcgtttta ttcaaaaagg agtttttgac
     8341 aaatgaaaaa acgtatatta tttatcggtg acagcattac agacgcagga agagaccgag
     8401 cagaagcaac tgatctaggt aaaggttatc cacttttgat tgccggaaaa ctaatctccc
     8461 aatatccaac gatgaaattt gaatgcatga accgtgggat aggaggagac aatattgcag
     8521 atctgcaagt acgctggcaa gaagattgtt tagctttaca acctgactat gtatcgattt
     8581 tgatcggaat caatgatacc tggcataata ctagcgatca ggctatattc ggaactgaga
     8641 aatctgcgca gcaatttgaa tccgtttatc gaaaattact aaatgaactt caaacagcgg
     8701 aaatctgcaa catcatcttg atggagccgt ttgtacttcc tataaccgac gaccgtcatg
     8761 gctggcgtaa agacttagac cctaaaatcc aaattgttcg taaacttgct aaggaatatg
     8821 gcgcattgct ggttccttta gatggcatat tcaatgcttt agggattgct tatggttttt
     8881 cgaaatatac aagagaagat ggggtccacc caacgattgg cggacatgag atcattgcac
     8941 aaagctggat agatgcaatt gccgcagtcg atttttttag tggagataaa aatgagcgaa
     9001 agaaaagtga gaaatgatgg aaatacggtg ggcagtaaaa gaagatttac ctcaaatcaa
     9061 tcagctgatt actgatcatc cagaatcatt cgtaaaagca aaaacggcag ctgacctaaa
     9121 tgataagaat aaactattgc tcgttgctgt aacaaaagaa aaacggatta tcggatttgc
     9181 gcaagcggac gtgcaacagt cagaagaacg ggtggatcag cgaccatcag gaaaactaat
     9241 ccaacacaca ttagtaacaa aagaaaatac ggaagaaatc caaaaaaaat ttgcagaata
     9301 cttgatgctg gaagctaaaa aaagaagaat aaaatcaatt tttgcccagt tttaatcaaa
     9361 aacagtaata gaaggagaaa tacaatgagt tgtttaggaa atgtcatctg gtttatattc
     9421 ggcggactaa tcggtggtct tagctggtta gcagcgggga tactttggtg tatcacgatc
     9481 ataggtatcc caatcggtat gcaatgtttt aagatcgcct ccctttcttt tgcgcctttt
     9541 ggcaaagaag taatttatca ccagtctggc atgtcattga tcgttaatat catctggctg
     9601 atcgtttcag gcctaccaat tgctctcgca catgtcgtca gcggcatcct tctatgtatc
     9661 acgatcatag ggataccttt tgccaagcaa tctttcaaac ttgctcgatt ggcgttgatg
     9721 ccattcggtg cagaaattgt ataaaaagag aataataaag gttagaaaac gcatagagtc
     9781 aggtgggata catgtatttc acctgactct atgtgttttc ctgtataagt tctcccatgt
     9841 gacttttacg tcttttattt atatgggatt actgtttatg gaaagttgaa ataattttca
     9901 ttaaagaact ctttctatat ttttgaaagc gtagtggagc ttcgaatatc tgggaaggac
     9961 attttgcagg gattgaaaaa agatattgtc ctatcgaaaa attaatgaat ttagacaaat
    10021 tgccagcaac aggcttcaaa cttagttgct atcctgtcaa gatcaagaag gcaagtgcgg
    10081 gttggataag agcaggggca atgatcgaag agaaaaagaa agaataagcc aaaacatctg
    10141 tatggaagaa attttccgat gcagatgttt ttcatttttt ctttcggata ccttgacata
    10201 tgaataacca ttcatttata attagttatg aagagatgtt catatgttga ggcgaggagg
    10261 tcattaaaat gaaaagttac agattagaag gtttagattg tgcgaactgt gcaatgaaaa
    10321 tcgaaaaagg agttcagaag atcaatggag tcaaggaagc aacggtaaac ttcacttctg
    10381 gaaaactaac gattgacgca gaggaagatc atttggctac gattgaacaa gaaacaaaaa
    10441 aagtagtgaa ggaattagaa ccagatgtca aagtaacaga aatagataag gaaaaagtat
    10501 ctgaacatgg aaatgaaaaa gagagaaata cgctgttccg gattttattt tcccttgcag
    10561 gtatcgcttt attgctatta tttgatttta atgaaccaat tcgcttgata gggtatttat
    10621 tgatttatct gctgatagga tatgatgtag tgaagaaggc agtgatgaat atcgtcaaag
    10681 gaaaaatctt tgatgagaat tttcttatgt ctgttgctac gattggcgct atgttgatcg
    10741 gtgaatatcc agaagccgta gcagtgatgc tattttatca aatcggcgag tatttccaag
    10801 gattggcagt cagtcattca agaaaatcga ttcgcgaatt gatggcgatc cgtccagaaa
    10861 cagctcacgt gcagacgacg gaaggattga tgaccgtgaa ccctgaagac gtgcagatcg
    10921 gtcagtttgt acttgtgaag cctggtgaac gtgtaccgtt agatggaacg atcatcgaag
    10981 gagaatcatt agtcgatacg tcagcactta caggagaatc agtccctaaa tctgtatatg
    11041 ttggtgaaac agtattaagc ggatttatca ataaaaataa accattttta gttcaagtag
    11101 aaaaatctta tgaaaattct actatcagca aattattaga attagtagaa aatgccagca
    11161 gtaaaaaagc accagctgaa aatttcatta ctaaattcgc gcgctattac acaccagtcg
    11221 ttgtaggatt ggccgtttta ttagctgttt tacctccact tgttgtttct ggagcggcgt
    11281 tttctgaatg gatctatcga gcattgacat ttttagtgat ctcatgtcca tgtgcattag
    11341 tgatttccgt gccacttagt ttctttggcg gtatcggagg cgcaagtaaa atcggtgtat
    11401 tagtaaaagg ttcaaattac ttggagttgc ttgcgcaaac cgagacagtg gtattcgata
    11461 aaaccggcac attaacgaaa ggtgactttt cgatccagac gatcgataca aaaatcgatc
    11521 caaagaaatt catgcaatat attgcgagtg cagaacagtt ttctacacat ccgattgctc
    11581 aatctgtttt agaaggctac gcaggtccgc ttttaccaac aactaatatc caggaatttg
    11641 caggtgaagg gatcttagct gaagttgatg gcaaacaagt attagcaggt aatcacaaat
    11701 tgatggaaag atttgaaatc tcttttcctt taagtcaaga aatcggtaca ttgctttatc
    11761 tagcgatcga tcaaagttac agtggttatc ttgttattgc agataccttg aaagaagatg
    11821 ccgtagacgc attggttcaa ttaaaacagg ctggtgtgaa gaacacagtc atgttgacgg
    11881 gcgactcgaa aaaaattgct gatcatatcg ggaagcaagt aggcgtggac aagatatata
    11941 gcgaattgct tcctgaagat aaagtgcagc ggttagagga aatcttacaa agaaacaata
    12001 aaaagaccgc atttgtcgga gatggaatca acgatgcacc ggtgctagca agagcagatg
    12061 taggaatcgc aatgggtgga ttgggaagcg atgctgcaat tgaagcagca gatgtagtca
    12121 tcatgaatga tcaaccatcg aagattgcag aagcaatcca tttagcaaag aaaacattga
    12181 aaatcgtcaa acaaaacatt gtctttgcta ttgggataaa aattttggta cttgccttag
    12241 gtgcttttgg ttttgcatca atgggagatg cagtatttgc agatgttggg gtgacagtat
    12301 tagctgtttt gaatgccatg cgaagcttgc atgtaaaaaa agaggacgaa tgaacgtcct
    12361 ctttttttta tatccttttc ttaatgaaaa atgtaaagaa aatagatagg attataaaat
    12421 aactaatgtt tttaattttg cagaaaattc aaaatagctt gaaattcaat aaggtcaatg
    12481 aaataaaaga aaataactta tttttttgat ggaaaaaata tgaaaaaacg atgtgtatta
    12541 aataaaagaa tacacacata aaataacact gtcttgtaag tttgttaaaa attgaatatg
    12601 attacatctg gataacaaat ttttatcata aaggagagaa cgaatgaaca acaaacaatt
    12661 acgctggttt actgttgcgt taattgcatt taacatggtt tggggcatgg ggaatgtagt
    12721 taataactat gctcagcaag gagtatcagt tgtcacctct tggctattga ttttggccat
    12781 ttattttatt ccatacgcat tgatcgttgg acaattagga tcagccttca aggatagtaa
    12841 aggaggcgtc agttcatggg tcgaaaatac gacatctaat aaacgactgg catactatgc
    12901 cgcttggact tactgggtcg tccatattcc ttatttggca caaaagcctc aagcaattct
    12961 gattgctggt ggttgggcag tccaaggaaa tggaaatatc gtaaatacga tgtcagtaca
    13021 aatggtagca gttatttcac ttattatatt tcttgccttt ttatatttat caacaaaagg
    13081 actttctact ttgaaagtga ttggcggact ggccggaaca gcgatgttcg tcatgtcgat
    13141 cttatttatt cttttagctg taacggcacc gttcatcaat ccaacgatgg aatttgccac
    13201 accacatatg aatcaagtga aaacatatat tccaacattt gatttcagtt atttcacaac
    13261 cgtttcgatg ctagtatttg cagttggagg ggcggaaaaa atatcccctt atgtcaactc
    13321 tacaagaaat cctgcaaagg aatttcctaa agggatgatc ttcttagcag caatggtagg
    13381 gatttgtgct gtattaggct cagtcgcaat gggtatgctg tttgctagtg ataatattcc
    13441 taaagacttg atggcaaatg gggcatacag tgcttttcaa attttaggta attactatgg
    13501 tatcggtaac tcattgatga tcatttacgc attgacaaac atgattggac aaatctccgc
    13561 attagccttt tcaattgatg caccactaaa aatcttgtta gcagatgcgg atccagaatt
    13621 tgtaccaaac tggctacgta aacgtaatcg taaaggtaca ttggtgaatg gttatcttct
    13681 gacaggtata ctagtaggaa tcattatttt gttgccgatt tttggtatca aagatatgaa
    13741 tgaattagta aaatggttga cgaacttgaa ctcagttgtc atgccaatgc gttacctatg
    13801 ggtgttcttg gcatatatga tgttgaataa agcttataag aaattcaatt ctgaatataa
    13861 atttgttaaa aatccaaaaa tcggttttat ctttggtgct tggtgctttg ccttcactgc
    13921 gtttgcatgt atcctaggaa tggtgccaaa agtagattat actgctgatc ctaaagcatg
    13981 gtggttccaa ttatttacga atatcatcac accaatcgtc ttgatcttat taggtatgat
    14041 cttgccagca attgctcgtc gagacaaaaa caaagaaatc actgaaccag aaacagtggt
    14101 tcagccttaa aatagaaata cttgttacaa gaggttgtga cagaagtggt cagcttcaag
    14161 aaataagaag gaatttacga aaattgcttc tcaaattttt gtgaagtttc ggcttgtttt
    14221 tcgaagaagc tacttctgga acaccgtgaa tcagaggttg tgaaaaagct gtcctgcatc
    14281 aagtaataag aacagccaaa caaaaatagc ccctcatatt tttcgtttgg ctgggcttat
    14341 taccgcagat gcaagctttg gaacaccgtt taaggaagag gttgtaaaat cagcgatttg
    14401 acctgagtat tagagaaaca aacggaaaaa tagctcctca tattttgccg ctttttgagc
    14461 taatgctgaa ggtcagctga ttgaacacca tttatt
//
LOCUS       DACBZK010000068        13427 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.071, whole genome shotgun sequence.
ACCESSION   DACBZK010000068 DACBZK010000000
VERSION     DACBZK010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.071"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..912)
                     /locus_tag="IVD66_002162"
     CDS             complement(<1..912)
                     /locus_tag="IVD66_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HAP6146361.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1340..1903
                     /gene="efp"
                     /locus_tag="IVD66_002163"
     CDS             1340..1903
                     /gene="efp"
                     /locus_tag="IVD66_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HAP6146362.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            2389..3648
                     /gene="lysA"
                     /locus_tag="IVD66_002164"
     CDS             2389..3648
                     /gene="lysA"
                     /locus_tag="IVD66_002164"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HAP6146363.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            3635..4435
                     /gene="dapF"
                     /locus_tag="IVD66_002165"
     CDS             3635..4435
                     /gene="dapF"
                     /locus_tag="IVD66_002165"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HAP6146364.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            4438..5319
                     /locus_tag="IVD66_002166"
     CDS             4438..5319
                     /locus_tag="IVD66_002166"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAP6146365.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            5316..6032
                     /locus_tag="IVD66_002167"
     CDS             5316..6032
                     /locus_tag="IVD66_002167"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HAP6146366.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            6038..6733
                     /gene="dapD"
                     /locus_tag="IVD66_002168"
     CDS             6038..6733
                     /gene="dapD"
                     /locus_tag="IVD66_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HAP6146367.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            6749..7750
                     /locus_tag="IVD66_002169"
     CDS             6749..7750
                     /locus_tag="IVD66_002169"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HAP6146368.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEKPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            7747..9108
                     /locus_tag="IVD66_002170"
     CDS             7747..9108
                     /locus_tag="IVD66_002170"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HAP6146369.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            9068..10219
                     /locus_tag="IVD66_002171"
     CDS             9068..10219
                     /locus_tag="IVD66_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAP6146370.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            10194..11363
                     /locus_tag="IVD66_002172"
     CDS             10194..11363
                     /locus_tag="IVD66_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP6146371.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            11538..12917
                     /locus_tag="IVD66_002173"
     CDS             11538..12917
                     /locus_tag="IVD66_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP6146372.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            13198..13427
                     /locus_tag="IVD66_002174"
                     /pseudo
     CDS             13198..13427
                     /locus_tag="IVD66_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4483 a         2339 c         2923 g         3682 t
ORIGIN      
        1 gtaaatgttt tttgataaat agcggtctgc tgcgtctgga aaaatcgtaa cgacacgatg
       61 accaggtggt aaacgacgaa tttctcttaa tgctgctgca aaagccgcac cactcgaact
      121 tccaactaat agtccttgtt ctcgtgctaa ctgcctagta tagttaaacc cttctacatc
      181 agagattgtc tcgatctgat tgattgaaag gggagaaaga aacggcggaa tgaattctac
      241 accgataccc tcaatttcgt gaggggctgg atcaccacca tttaacacag agccctctgg
      301 ttctacaccg attattcgaa tgtcgggata tttttctttc aaaaaggtag aagttccagc
      361 aaaggttcca ccactcccaa ttcctgctac aaaactatgg atattttctt tgatttcatg
      421 aaagatttct ggccctaacg tatgatagta agcagcagga ttatctttat tttcaaattg
      481 aagaggcaga tagctgtttg atatctcctc tgcaagtttt ttacttttgc tgatggcacc
      541 gatgattcct tgctcactag gagaatggat gatctttgct cccaatgctt tcatcaattg
      601 ttgtttttct aagctaaact tctctggaac aacaaaaacc gttcttaatt tgtatgtgag
      661 tgcggccaga gcgatcccaa ttcctgtatt tccggcagtt ggttcgatga tcgtcgtttt
      721 ttcattgatt tttccttggg caaatccttc tttgatcaaa taactgccca atctatcttt
      781 gatacttcct ccaggattta aatattctag ttttgcataa atagcagaac ctttaggcat
      841 agaatagtgc tgattgtcaa agcgataaag cggtgtggaa ccaatagctt ctgtaattgt
      901 cgagataatc atgtgggcct cctaaaaaaa gataataaaa aaaggagctg actattaaat
      961 cagctccttg aaagacatag agaaaaattg agtagataaa aagataagtt acctggtact
     1021 cattctatga agggcaatta atagacatga caaatagtat gctgctttta tgcaccatac
     1081 aacagcaacg attcaattgt ttttggttgc tgactgtcat gtgtatccct ccaagtaaaa
     1141 tttttattaa cgatagcatg aaaaaaaata aaagtcaaag gcttgaaaga aaaaaatatt
     1201 tcgatagcat cgtttacccg tgtttatttt tctgacaaat aggcatgaga ccttaaaaga
     1261 tagagaatac tctagttttc tggccggttg tctgatacaa taaagttgat tatgataaag
     1321 aaaagaagga gcaaaaataa tgatctcagc aagtgattta agagccggta tgactttcgt
     1381 acaagacggc aaactgatta aagttctgga tgcaagccac cataaacctg gtaaaggaaa
     1441 tacagttatg cgtatgaaac tgaaagatgt ccgttcaggt gcaacatacg acacaacgtt
     1501 cagaccagaa gaaaaatttg aaaaagcaca tatcgacaca aaacctgtac aatatttgta
     1561 cacgatggat gatacagctt tcttcatgga tttggaaaca tatgagcaat atgaaattcc
     1621 tgtagaaaca gtagaagaag aaatgaaata tatcctagaa aacatggaag taaaaatcca
     1681 atttttcggt agcgaagtca tcggcgttca attaccaaca actgtcgtat tacgtgttgt
     1741 ggaaacacaa ccttccatca aaggtgcaac agtcactggt tcaggtaagc cagcgacaat
     1801 ggaaactggc ttagtagtca atgttcctga cttcatcgaa acagatgaat tgttggaaat
     1861 caatacagca gaaggttctt atgtaaaacg tgcgtcaaaa taattcgcta acggattgat
     1921 aagaatttga aaacagagct tgacctcttg aaaggcagat catcggatct gcctttcaag
     1981 aggttttttg tggaatcagc aaattgaaaa ataaaaaagt atttgatttt atttatattt
     2041 tgaaagatga atggcaaaag ctagagaaag aaaaaactgc acttatttat gaagaaattg
     2101 aaatgattca taaaattgaa aatatccgaa ctattccgaa ctatattgaa gcgaaaatat
     2161 tttttcatca ctaaatagtg ttgaatttat gtttttatgt ataaatagct tctaatagtt
     2221 cgggtatttt gtttttataa ccatttttat tcttattttt aaaaaaatat ttcgaaatat
     2281 actagacaat tcagaaaatt ttgtttaata ttattccaat aaaattcaaa tctttatcaa
     2341 atgaaattcc aataaaaacg gaaaaaaagt gaaaagagga atgaaaaaat gacagaattg
     2401 ataattggcg gagtcacagc aagcacattg gcagaaaagt ataagacacc tctgtatgtg
     2461 tatgatgaag aaaagatgag acaaacgatg ctgtcattca agcgaggctt tgtatcgaaa
     2521 cgttttgata caaaagtgct ttacgcctct aaagcattcc aaacgattga gatgctgcat
     2581 ttagttcgtg aatatggatt cgggctagat gttgtcagtg gtggggaaat ctataccgct
     2641 ttgcaagctg attttcctag agatactatc tacttccatg gtaacaacaa gacgccagag
     2701 gaactgatct atgcacttga aaatgatttg ttgcatattg ttgccgataa tttgatggaa
     2761 gttgaattat tagcagaatt aagccaacgc tatttaaaaa aaatctgtat catgcttcgg
     2821 ttgaatgtcg gagtagaagc acatactcat gaatatatcg tcactgcgca tattgattca
     2881 aaattcggca tgagctatga aagtaaagag tgccaacaag cccttcagtt gataaaagaa
     2941 agcagctatc tagagttaga aggatttcat gctcatatcg ggtcacaaat ttttgatgtt
     3001 actgcttggt tagctgaaat cgacaaattg acgaattact taaccgattt tgaccaacct
     3061 ctttccttga atcttggcgg agggtttggg attcgttata cacaaaatga tcagccgatc
     3121 ccagtcgaag aggcactaaa aaaactgatt gaatatacgg aagaagcttt ggaaaaacga
     3181 aaactgacca ttcgtcaatt actgatcgaa ccgggtagaa gtattgttgg agaagctggt
     3241 acaacactat acacgattgg tttcatcaaa aagacaccac ataaaaaata ttactttgta
     3301 gatggcggga tgacagataa tatccgtcca gctctgtatc aggcagaata cgattgtgat
     3361 ttagcagcaa aactgtcgga agaaaaaaca gagaaagtga cgattgcagg aaaaatgtgt
     3421 gaatcaggcg atgtggtaat taaagaagct tatttgccga aagcagaatc gggtgatctt
     3481 ttagctgttt attccacggg agcttatgga tactcgatga gcagcaacta caatcgagcg
     3541 acacgaccag cagttgtttt tgtcaataat ggccaatcaa gactgattgt tcgcagacaa
     3601 gcattttctg atctactaag gggggaagtt tcctatgatc cttcataaat ataatggctg
     3661 cggaaatgat tttatcttat tagattacgc agaagacaca gattatagtc aattagccgc
     3721 ttctttatgc acaaaagaaa aatatgatat agacggattg atcgccgtaa aaatcgatcc
     3781 gttggaaatg atctattaca acaaagatgg cagccgcgcg ccgatgtgcg gaaatggcat
     3841 tcgctgtttt gctcgatacg taaatgatca gaacatgatg aatgaacagg aattcaacgt
     3901 agagacatta gcaggcacaa gaaaaattac ggtgttggat ccctcacctt tttattgcag
     3961 cgtagatatg ggagtgccag atgattctcc ggaaaaaatc aaagctaatc aaacttatcc
     4021 aataaaaaac caggaaatag agatcaatgg tgaaaaagta acgatcacta gtttattttt
     4081 aggaacgatt cataccgttg tttttgttga aaatgcgcgt gaggaagtct ggagaaaaag
     4141 aggtgaactg atctgtcatc atcctttgtt caaagaaaaa accaatgtca actttgtaga
     4201 agtagtcaat gaacaagaat tgatcgtccg tacctatgaa agaggagtag gttggacact
     4261 tgcttgcggt acaggttgct gtgcctctta tgtggttgct aaggaaactg ggaaaatttc
     4321 agcagatcag gtagttgttc acttggaaca aggagacttg atgatctctg gtgaggatgc
     4381 gatacaaatg gctggcccag cagttcatga atggacaaga atattggagg aatgaagatg
     4441 ataaaaggtt cgatcgtggc gctgatcacg ccgatgaatg aagagggatc agtagattat
     4501 gctggtttgg aaaaattgat ccaattccat ttagatgaac aaacagatgg attattagtt
     4561 ttaggtacaa caggagaatc ttctacgctc acacaatctg aggaggagca gatccttcaa
     4621 ctgacagtaa agaaagtggc tggccgtgtg ccggtgattg caggagctgg aacgaataat
     4681 acgaaagaaa cgattgaaaa agcgaagcat tttgcttctt tgggggcaga cgcacttttg
     4741 gtcatcaccc cttactacaa caaaacaagt gatgcaggac tagctgctca ttttacagca
     4801 attgcagaag cctcaccgat tccgcttatt ttgtataatg ttccttctag aacaggcatg
     4861 tcgattccaa tccatgtatt agtaaattta gcagaacatc ctaatatcat tggtttgaaa
     4921 gaagcctcag gagatatggc ttatgtgatg gatgccgctc ggttgattgg agaagaattc
     4981 ttcctttaca gtggaaatga tgatttgatc ctaccagtaa tgagtgtagg aggaagcggt
     5041 gtaataagtg tatgggcgaa tatccaacct aaaatagtcc atgaattagt aaaagatacg
     5101 caggacggaa gatggcagca agcaaaagaa aagcaattaa atgcacttga actgatccat
     5161 gccttgttca gtgagaccaa tcctattcct gtcaaagcag ccatgtcatt attagactta
     5221 ccttccggac ctctacgcct gcctttagtt tctctttcaa aagagaaaaa gaaacaatta
     5281 gctcagcttt tgttaaaaga aaggacggtt gaaaaatgaa aatcggactg attggcagtg
     5341 gacagatggg aaatagagtc gaagaagttg cacaagaaag aggagatacg gtccttcttt
     5401 tacggacggc acctaaagaa gcaactacgc ttgcttttac ggaactgcca gaactgctta
     5461 ttgatttttc tcatccagat aatttagaga aaatcctttc gtatagctta tcatatcaac
     5521 ttccgttagt cattggcacg acaggttata cacaatcaca gttccaagaa ataaaagaac
     5581 atgccaaaca tgtacctgtg atgtatagtg ctaatttttc gttcggcatc atggtgatga
     5641 atcaactaat caagcaagca gctgcaatgt tgcaaggctg gcagatcgaa ctgattgaaa
     5701 aacatcatag tcgtaaaaaa gatgcaccat ctggtactgc aaatatgctg cttcaaacaa
     5761 tccaagaagt gcaaaagctg cagcccgtat acaactggca agggaaaaaa agagaagaaa
     5821 accaaattgg tgtacacagt attcgtgcag gttctttacc tggtgaacat gatgtattgt
     5881 ttgctgctac tgatgaaata tttacgatca aacatgaatc tttttctaat cgaatctttg
     5941 ctgcaggcgc agtagaagca gcggactggt tgaaagatca gtcaccaggt tattacaaat
     6001 tagaagattt attaatggac aaaggggtgt aaaaaacgtg gaagctcaag aaatcatccg
     6061 ctacattcaa acggcatcta aaaagacgcc tgtgaaagtc tatctgaatg taaccgagcc
     6121 aatcgaattt aaagaaagta aagtttttgg tgaaggaagc agcttcgttg tttttggtga
     6181 ctatgagacg attgctccgg ttttagaagc tgaatcagaa aaaatcattg aaatcgaaat
     6241 cgaaactgct gcaagataca gcgcagttcc tttgctagat attaaaaaaa ttaatgctcg
     6301 tatcgaacca ggtgctatta tcagagatca agtgtcaatc ggcaacaatg ccgtgatcat
     6361 gatgggagcg attatcaata ttggtgcagt aatcggtgaa aacacgatga ttgatatggg
     6421 tgctgtctta ggtggacgag cgacagtggg caaaaactgc catattggtg caggagctgt
     6481 cttagcaggt gtgatcgaac cagcatcggc caaaccggtt atcgtagaag acggcgtact
     6541 ggtaggtgcg aatgcagtga ttgttgaagg tgtccatatc ggaaaagatg cagtcgtggc
     6601 agcaggagca gtggttttag aagatgtggc agcagaaact gttgtcggtg gaatacctgc
     6661 acgtgtatta aaaataagtg atgatcagac aaaagaaaat acagcattga ttgctgcgtt
     6721 acgcgaatta tagaggagat ggagaaaaat gcgcgaaata gatacctgta ttgtgggggc
     6781 aaccggatta gtcggccaaa cgatgctcaa agtgttagaa gaatatgatt ttccagtagg
     6841 acgattgaaa ttattagctt caaaacgttc agccggtaaa gtttgtgtat tcaagaaaaa
     6901 gaaacacact gtacaggaat tgacagaaac ttcatttgaa ggatatgatt tagcgctatt
     6961 ttctgcaggt gcttctgtat ccaaagagtt tgcgccaatc gcacgaagtc agggactatt
     7021 tgtcatagat aattcctcag catggcggga agattcggat attccattaa tcgttccaga
     7081 ggtcaatctg gaagactata cattgaatcg gctgattgca aatccaaatt gttcaaccat
     7141 tcaagcggta cttccgctta aagctttaca agaagccttt ggtatccagc gagtcaatta
     7201 ttcgacctat caagcagttt ctggttccgg gcaaaaaggc attgaagatc ttcatcgtac
     7261 gcaaaatgac gagaaaccag ttttgtatcc ttataatatt agccaaacgg tgattccgga
     7321 aatcgatcag cctttggaaa atgggtatac aaaagaagaa cagaaaatga taaatgagac
     7381 ccgtaagatt ctgcatcagc ctgctttgcc agtatcagca acctgcgtac gtgtgccaat
     7441 cgaaaatgga catggagtct ctgtggcagt tcaactgcaa aaagagttta cgacggaaga
     7501 aattagagag tgtctcagcc agtttccagg gattcaatta gaagatgatc tagcagcaca
     7561 taaatatccg acgagcattc ttgctagagg aacagatatg gtttatgttg ggaggatcag
     7621 aaaagacact tctttagaga acggattgtt gttctatacg actgccgata acatacgcaa
     7681 aggagccgct gcgaatgccg tacagattgc tgcagcttta atgcagaaaa tagcggaggt
     7741 ggcaagatga gtaatacgct gaaagtagcg aaattcggcg gaacatcgat gtctcatgaa
     7801 gagcaattca aaaaagtccg tacaattgtt ctttcagatc ccaatcgcca agtgatcgtt
     7861 gtttctgctt taggcaaacg tacgtcagat gatgacaaag taacagactt actttatttg
     7921 atttatgctt accttcagca tcatgttgat tggacacccc tttggaaaag gatttgtgat
     7981 cgtttcattc aagtaagaga tgttcttgcc ctgcagttac ctattgaaga tgaactagca
     8041 cgcatacaga aacaactgga agacgaaaag ataactgaag attatttagt aagtagaggt
     8101 gaatatctga ctgctcaact gatggctgag tatcttggtt accagtttat tgacgcaaaa
     8161 gacctgattt tctttgacta tgatgggaaa atcgatcagg aaaaaacagc acaggaaatc
     8221 acaaaagcat ttaaaagata tccgaaaatg gttgttccag ggttttacgg ggcgaaccct
     8281 gcaggaaaag aaaaattatt gggccgtggg ggaagcgaca ttaccggcgc gatactggcg
     8341 aagatgttgc aagcggaaag ttatgagaat tggacggatg tttcaggaat catgatggct
     8401 gatccgcgaa tcatcgatca tcctaaaatc atcgaggaaa tctcttttag agaactgaga
     8461 gagatggctt atatgggggc taacgttctt catgaagcag ctgttttccc agttcaagag
     8521 gctgatatcc ccatccaaat aaaaaatacc aatgatcctt tcgctcaagg gacaaaaata
     8581 tcgaatcacg aaatagaaaa ggaaaatgga ctgacaggaa tagctggacg caaggatttt
     8641 ctttccatca ctttattcaa acgtcatatg tccgatgaaa tcgggtttat ctggaaagca
     8701 atgagcattt ttgctaaaca tgagatatca atcgaacata ttccttcagg gatcgacaat
     8761 atcggagtga tcgtctcagc agaagcgatt gccgataagt tatttctcat cacgaaagaa
     8821 ttaaaagaaa cacttggcgt ggaagaaatc gtcgtgatcg aagacttagc tttgatctct
     8881 gtcgttgggg gtccgcataa agaattgatt ggattatctg ggaaagtgtt atcgatattg
     8941 aacaaattag aaattcgcac atcgatctta tcacaaggag cacaggagtt gaatctgatc
     9001 atcggtgtac cgaataatca atatgaaaca gtagtgaagg gtatctatga agggatggtg
     9061 aatacggatg ctgaaagaat atcgaatggc actccatcaa attcctgaaa tcgggtttca
     9121 tgaattcaag acaaaaaaat atttatatga acaagtaaaa aacagcgagg ccgttatcca
     9181 tgaaatcggc gaaacaggac tactccttta ttttgataat cagcaagaag aaacgattgc
     9241 ttttcgaaca gatatcgatg cactgccagt caaagaagaa acgaatctct cttttgcttc
     9301 taagcatgaa ggttatatgc atgcatgtgg tcatgacgga catatggcga tgcttttagg
     9361 gttgactgac tttataacta aacacattga ggatcttatt tataatgtag tactgatcta
     9421 tcagccatca gaagaaattt ccggtggcgc acaaagcgtt attcagtcag gattgttgga
     9481 taaatatgaa gtacaagcaa tatttggctt tcatctatgg cctggactag ctaagggaga
     9541 agttttctct cgaccaggac ctttgatggc acaaagcagt gaaacagaca ttatcattaa
     9601 aggccagtct gcacatattg cttctagtga aaaaggaatc gatagtctgg aggcagctgt
     9661 acgatttttg aagaatgttt atgattttga ccggcaatta ccggcagagt ggaatcatct
     9721 aatgaaattt ggccaaatcc aaggtggaac gatccgaaat gttttagctg gagaagttat
     9781 tgtatccgga agtatccgtt cttacagttc agatatgcaa aattatttga agaggggatt
     9841 agaccattta gcagaacagt ttcactctac agctactatt tcttttcgct ataatgacgg
     9901 ctatccagct gtaatcaacc atagaggctt atatgcagca ctgttagatt caaacaaact
     9961 acatgaatta gatgctccag ttcttcaagc cgaagatttt ggcatatata cgcaacaata
    10021 tccatgtgta tttttctttt taggtgtcgg tgatacccct gctttacatg atccgacgtt
    10081 cgattttgat atggatgttt tagaaaatgg tgtagaatgg tacaaaacga ttctttttac
    10141 agaaaatctt cttgtaaaaa tcgatagcag ttcaaaagag gagcgagtaa ataatgatga
    10201 atttatccaa tcgatttagt cctaggcttt ctagaataga agtatcaaaa atacgacaat
    10261 tcgatcagca aatatcgtcg ataccagatg tgatcaaact caccctggga gaaccggatt
    10321 ttccaactcc tgaacatgtc aagcaagcag gaatagcagc gattgaagaa gacttttctc
    10381 actataccgg aatgagagga ttagaggaac tgcgggaagc ggcttgtata tttcagcaac
    10441 agcgttatgg attaacttat gatccgcaaa cggaagtttt gacgacagtt ggtgcaacgg
    10501 aagcgattgc ctctgcgttg ttatctgttt tggaagaagg agacaaggtt cttattccag
    10561 cgcctgctta ttcaggatat cagccattag tggaactagc tggtgctgaa ttgatcccga
    10621 tagatacttc tgacacaggg tttgtctgtc agccggaaca atttgaacga gcatttgaac
    10681 aatatggatc agctgtcaaa gcagtcattt taaactatcc taacaatcct actgggacga
    10741 cattgtctgc aaaacaattg aaagcaatcg ctgaggtttt aaaaaaatat ccggtatttg
    10801 ttataagtga tgaagtatat gctgaattga cttatagtgg aacgcatatg tccatagcta
    10861 cttatcttcc agaacaaaca atcgtgataa gcgggttatc caagtcacat gcgatgactg
    10921 gttggcgagt gggctttatt tttgctcaaa aagcccttat tgacgaacta attaaagtcc
    10981 atcaatatct ggtgactgcc gctacaacga tgtcgcaaaa agctgcggct gaagcgctaa
    11041 taaatggggt gaaagatagc gagaatatga aagagcaata tcaaacacga agagactatc
    11101 tggtccagca attggcgcct ttaggatttg aagtgaccca gccaaacggt gcattttact
    11161 tgttttgcaa actcccagct gccattcaaa ctgactcttg gcagttttgt gtagaattag
    11221 cggaacaggc aaaagttgcg tgtatcccag gaattgcatt tggcccagaa ggagaaggtt
    11281 atatccggat ttcttatgct agcagcatgg aaaaattaca tgaggcctgc aaacggatca
    11341 aagacttttt aacagaacag tgattcatag attttatcaa aaaaacaatc gttaattttg
    11401 cggtatattc tgcaaggaga cgattgtttt ttaaatttag ttcaaatgaa cgcgtttctt
    11461 ttgattcata actaatgtaa tgttaagttt aaattgttta gaatgatttt aaaagaatat
    11521 tcaaggaggt ttcatcaatg gaaaaaatca aagttgtcat tgtaggtgca tctcatggag
    11581 ggcatcaatc gatcttggaa ctattgacac gatacggtga aaatgtagat atcacgctat
    11641 ttgaagcagg agactatatt tccttcatgt catgtggtat ggagctgtat ttagaagaca
    11701 aggtaacaga tgtaaatgat gtacgtaatt tcagaccaga aaactttccg caatccaatg
    11761 ttcatatttt aaataatcac gaagtaaaaa cgatcgatgc cgataaaaaa acagtaacgg
    11821 ttactagcgc atcagataac gaaacaaaag aatatcctta tgacaaattg attttgagtt
    11881 ctggtgtcaa accaaacaat ctgccagtac caggagcaga tctagaaaat gtctacttga
    11941 tgcgtggata caattgggca accaaaatca aagaaaaatt aaatgatccg gctattaaaa
    12001 aaatcgctgt cgtaggtgcg ggttacattg ggatcgaagc agcagaagca agccgaaaag
    12061 ctgggaaaga agtcgtattg cttgatgtga tcgatagacc tttaggcact tatttagatg
    12121 ctgagatgac agatatttta gaacaacacc taaatgaaaa cggtattgaa gttttgacaa
    12181 atgcaaaaat cgaagctttt actggtaacg gaaaagttga ggcaatcaaa acaagtgaaa
    12241 aagaaatccc agcagatcta gtcattcaag ctgccggtgt gaaggcaaat acagaatggt
    12301 taaaagggat cgtcgactta gatgaacgtg gctggatcca aacaaatgaa tacttgcaaa
    12361 cgaatcttcc agatgtgtat gcagtaggag atgctacact tgcttattct atcccagcac
    12421 gcaaaaaaat gccgatcgct ttagcgactg ttgcacgtag agaagcacgt tatgtagtaa
    12481 aacatctttt tgaagaagta ccaaacaaac cgttcggcgg agtcgtaggt tcctctgcat
    12541 taagtgtctt tgactatcat tttgcagcaa gcggattgaa tagctttaca gcagcaaaag
    12601 caggagtaga tgtacgagtg tcttattatg aagatacgtt acgaccaaaa tatgtaccag
    12661 aagaacaagg aaatccaaaa gtgtccatcc aattattctc ggatccaatg acccatcaat
    12721 tgctaggagg agcagtatta tctacctatg atgttacagg tcaaggaaat gtattggcac
    12781 tagcgatcca aaacaaactg actttagaag aactagcaga agctgacttc ttcttccagc
    12841 caggctttga ccgacaatgg agcatgttga atctagccgc tcaacaagcg ttaggagaag
    12901 aaccatttgt agaataagaa aacgaaatat ttgaaaagag gttgtgaaaa agctgccttg
    12961 catcaagtaa taagaacagc caagtaaaaa cagcttctta tgtttttaac ttggctggac
    13021 ttattaccgc agatgcaagc ttttgaacac cgtttatttt caaaaaaggg actgtgacac
    13081 gatttgtgta ccgaccccca aaagttagac caaaaaatct aacttttgga ggtcggtatt
    13141 ttttatggtt aaatatactt ttgaacttaa attaaagatc gttcatgatt atttggatgg
    13201 caaaggcgat tggaccgtaa aaatccagat caagagattg aagcggaaat gcttaaaatt
    13261 cgggagaagc acaaggatta tggctgttta cggatgacca atgaactaag aaaccgcggt
    13321 ttctctatca ataaaaagaa agttcagcgc ttgatcaaga agctaggaat aaaagtaacg
    13381 gcatacacgc gtaaatcacg tcgctacaat tcttatcgag gaaaagt
//
LOCUS       DACBZK010000069        13395 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.072, whole genome shotgun sequence.
ACCESSION   DACBZK010000069 DACBZK010000000
VERSION     DACBZK010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.072"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(14..706)
                     /locus_tag="IVD66_002175"
     CDS             complement(14..706)
                     /locus_tag="IVD66_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP6146373.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            791..967
                     /locus_tag="IVD66_002176"
                     /pseudo
     CDS             791..967
                     /locus_tag="IVD66_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(1143..1712)
                     /locus_tag="IVD66_002177"
     CDS             complement(1143..1712)
                     /locus_tag="IVD66_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP6146374.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1786..2109)
                     /locus_tag="IVD66_002178"
     CDS             complement(1786..2109)
                     /locus_tag="IVD66_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146375.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2263..3075)
                     /locus_tag="IVD66_002179"
     CDS             complement(2263..3075)
                     /locus_tag="IVD66_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146376.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3429..4277
                     /locus_tag="IVD66_002180"
     CDS             3429..4277
                     /locus_tag="IVD66_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HAP6146377.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4422..5363
                     /locus_tag="IVD66_002181"
     CDS             4422..5363
                     /locus_tag="IVD66_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HAP6146378.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREIPFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5353..7524
                     /locus_tag="IVD66_002182"
                     /pseudo
     CDS             5353..7524
                     /locus_tag="IVD66_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7636..9807)
                     /gene="copB"
                     /locus_tag="IVD66_002183"
     CDS             complement(7636..9807)
                     /gene="copB"
                     /locus_tag="IVD66_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HAP6146379.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(9827..12013)
                     /locus_tag="IVD66_002184"
     CDS             complement(9827..12013)
                     /locus_tag="IVD66_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HAP6146380.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(12013..12222)
                     /gene="copZ"
                     /locus_tag="IVD66_002185"
     CDS             complement(12013..12222)
                     /gene="copZ"
                     /locus_tag="IVD66_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HAP6146381.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12235..12675)
                     /locus_tag="IVD66_002186"
     CDS             complement(12235..12675)
                     /locus_tag="IVD66_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HAP6146382.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12749..13288)
                     /locus_tag="IVD66_002187"
     CDS             complement(12749..13288)
                     /locus_tag="IVD66_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP6146383.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         3761 a         2810 c         2382 g         4442 t
ORIGIN      
        1 agggggggat tttttatcgt tgtggaatat ttaaatacca acgcttgtca tgaaaatctt
       61 gtgctccacc cttagtattt ccttctggat cgtttgtcgc acgcatcatg acgtatactt
      121 tcttattagg gaaatcacgc atattgaaag atacatgata gccaacattt cctaaagtat
      181 tataagcttg atttacgtct ggtctataaa tcccatcagc tcttactcta gctagttctt
      241 ttccagtatt gtagtccata atgaaaatat actcgtattt ataattagca atgtgccatc
      301 cagctacatg caagtttgcg ttttcgattt ctccgaactg atcaatgtgg gcgtaatttg
      361 ttccatctgt cagcgtagaa tttgcagcac ctgctcgagt tggatcaatt actggtttat
      421 cctccgaagt agttggatta tcatccgtaa aaccatgagc caaatcatag gctagttttt
      481 ctttacttac acccatttca gaaagataac cgtaaggatc tgtatgatcg ccccaaatat
      541 tttgtgttac ccataaatgc gatttgattc ctggttggtt ataaggagtg tctaatgtta
      601 atggaatacc atatttcatt gctgaatctc ttgccaattc aacgtatact ttatagttct
      661 tttcaaaagt ttctttatca tgtgtatgtt gtaactcgat ttgcacagga cttttggctc
      721 acgaggttgt cctactctac atcttgctga tagatatgct gaaaggaaaa caccaacatt
      781 atgttttgct ttttcagcta gaacgagaca agcaggaata cctttagaag atatcaaagg
      841 ttttttaggt cataaagatg tttccactac acaagtctat gcccatattt ctcccgaagt
      901 gaaaaaaaga tcaatgaatc aactagaaaa ctatatagaa gagcaaataa aaaagcactc
      961 aaattgagtg cttttttaag ctcactatca ctaaaactat cactaatttt atttataagc
     1021 gaacatgttt ctatcactga ttttttaaat ctagcgaaaa acccttatct taaaggcgtt
     1081 cgttcaattc tttggcaagg tcttcaaagc ctggcttgcc tagaagtgcg aacatggttt
     1141 tcttatagct catgtagaaa aattttcttg atgatgattt tatccatcaa ttgagattga
     1201 ctgttttgct ctcctatgat ttcagctatg attgtccgat tttgcggttt tcttcttaac
     1261 tggtagttga ttttcccagt ttccatcaac tcgctaagca tatccacgac tccgccaaat
     1321 ccggtctttt tcgtaataaa acctagtgct accattcgtt catctagatt ttttgctgta
     1381 atcgtcacac cagtaatgag cgagtgctgt aatgtttggg ccagctcttc catcccttca
     1441 gcattggata cgacggaagc tgttttgtta ataggttctt cgtttatttc ttttggttct
     1501 ttcctctcca ctttcactgt ttgacgaagg acatctagtt cttgcaagag cgtttcgtat
     1561 tgttcttggg tcagcatcac gccagctact ttttcacgat taaatatata tacgccagtt
     1621 cccgcgtctc gcgcttgagc aaatacatcc atcggcgatc gtttcacttc tgtgatcgaa
     1681 gatgtgggaa cttctaattt ctttaattcc aatggatttc ctcctttact aatcgctttt
     1741 tattatagca cagactgact tgttttgatc ttttttccaa aggttttatc ggtttttgcc
     1801 taaccagtaa ttgatatcgg taagaagtct ttcgatacca aatgaaggat ggtacagata
     1861 cgttttttga tcttcgttat ggtctagtgg aaaaaaatga tcgatgatca ctagatctgc
     1921 ataccgaggc ggcttatttc gagtacatac atgtatagag atccgttttc gatgtcttag
     1981 cgttttgttc agtaccccag caagtcttct tgcttcttgg tgttcatagc gaaaaaaaaa
     2041 gacgattttc acttcaggag ggtggacatc taaataccct cgttcctgga gtgttttcag
     2101 taaaagcatc ccccactcta ctgcggggtg tgcaagtgct tgttggatcg ctagccgaaa
     2161 ttgatatagt ttatctttgg aattgggaaa tttttctaat gtttcctgat aataacgaac
     2221 ttcttctatc agccggtcat ggataccaat tacgtaacga agtcattctt ggtaaagtac
     2281 ttttgtcagc tttgatttgc tttcgctctc aaattcgcta ttcagccaaa acagcgaatc
     2341 aagcttttca gtcacaatcg tcaatttccg atagtcttgt gtctcttcta tccgtttcca
     2401 ccgcttttca gtaatctggt tacagctcaa gcgcaaaatt gctagataat ttttttcttt
     2461 tattggcaaa atctgctcct ctctaaatag caattcagga aacaattcaa agaatagtgt
     2521 tcgactgtct cctaaaatct cgatttctgc cggatccttt ctttgcttca ataattggat
     2581 gaacatctca gaaaaggact gctctccatc atctgcaaaa aaatgcggaa aatctttcaa
     2641 aaagcaaaac agcagatatc ttacttttct ttctgaacca aagatctgtg cttttttata
     2701 agaaaaagaa aggtggtact cgccaaacca ctttctcaat cgctcttgcg tagaacgatc
     2761 gtacttctgc tcgtaaggtt cattcaatag cagatttttc agtaaacaaa acgggggtga
     2821 ttggatcaga aaaacaaaca agagataagg ttcgctatat ccttgatcat aaactaactg
     2881 aacggttttc ttatgaagaa tcagctgaat gggacagtcg ctttccgcca aacgtttcag
     2941 atgccgatcc actgttttaa catcgatttt cagttcttca gctaaatcag cttttcgcca
     3001 gatcaaatct ttcattagat tgattagtga aaataaattc tgtgcatttt ttgataatag
     3061 tttttgccat ctcatcgatc atttctcacc tgatttctaa acatattgtt tgatcaaaat
     3121 gggttcactc ctaaaaagat aaaaaactcc ctttctattt atttaaatac gcaaatcttc
     3181 ctcattattt tttattttac tcaatttaat cgtattctca tttcaaaacg aatgtacttt
     3241 aaaaaaacat aataagatca ctttgcttgt aggatgtatt cccttccatt acaatgaaat
     3301 aaatagcgat tttatgagaa ggtgatgtga aaatggaaga aaaaatagaa gaatccaaac
     3361 aaaaaatcga tcagttgata taagaattag aaaaagcggt catcggcaaa cgttcaacta
     3421 tccaattgat gatcgtggcc ctattagcag gtggtcatgt cttattcgaa gatattcccg
     3481 gtgtaggtaa aacgttactg gtcaaagcac tagcaaaagc tgtacaggga accttcagca
     3541 gagtccaatg tactcctgat ctgctgccta gtgatattct tggtttttcc gtatacaatt
     3601 cacaatcaaa agagtttgaa tttcgtccgg gaccgatctt taccacgatc ttgttagcag
     3661 atgagatcaa tcgtacgact cctcgtactc agtcagcact tttagaagca atggccgaga
     3721 atcatgcaac gatcgacaac aatacatacc ctctagacaa tcattttttt gtcttagcta
     3781 cgcaaaatcc aatcgagtac gaaggaacat atcctttgcc ggaagcacag ctcgatcgtt
     3841 ttttattccg actacaaatc ggttatcctt cttttgatga cgaacttttg ctacttttgg
     3901 ataaattcga aaaagtgttg gataacttaa atgaagtatt gaacagttat gaaatagaag
     3961 aaataaaaac aaatgtggcg aatgtctttg tcagtcccga agtggcatct tatgccttgc
     4021 agttagtgtc agcaacaaga agtcatgctg ccatccagct tggcatcagt ccacgaggaa
     4081 gcctttcctt tattcaggca gcaaaagctt atgctttaat ccatgggaga aattacgtca
     4141 cgcccaaaga tttgcaggat ttagttcctt acgtgttttc ccatcgcctg attttttacg
     4201 atcgttcatt gaaggaagac gaaaagaaac aaatcattca tactcttgtt gcacaaattc
     4261 ctattcctgt gaggtagatt gaggtagaca atggaaaaaa tcaaagatta tttcattaat
     4321 tttgtgttat ttctggtata tttcatcatt gtgctttttg ctcttgtatt caacaattct
     4381 ttaggctggt tcttgttggc cttttttact ctttatgtat catggagctt gatttcatta
     4441 agcagctttc taaagaaact ttcggttact tgtacattgc agccactcgt ttatcgcaaa
     4501 aaaagtatgc aggttatttt ttccatagca aaaaagagaa ctttttcttt acctctccct
     4561 cgtttacaaa tcggcttccc agcaatcttt gcagaaaaaa acaagagatt ttgattctta
     4621 caaataaacc gcaagaagtc caattgcttt ggcagccaaa agaaagagga tgccatgaaa
     4681 cattaactgt catttttaca gcctatgata gtctaggact tttcagaaaa agtgcaaaaa
     4741 gagagatccc ttttcctgtg actgttctgc ctgctttttg taagattcaa gcagaaaaat
     4801 tacagagagt tctggaaaaa aaacagcagc tgaacgcgta ccaaagaggt cttgattttc
     4861 gggaacatcg cgcttatcgt ccaggtgatt ctttcaaccg aatcgattgg aaattgtctg
     4921 ctcatactca agagtggtta taccgtgaat acgattatca agaagaagaa tgttctcctc
     4981 ttttttgctt ttggggttcg cccagtccaa aatttgaacc tctgctagac ttgtattttt
     5041 ctttatggca tttgagaaaa gaaaagcagc cggaacttct gatattaggc aaccgcgcct
     5101 ttcatggcaa agaccccggt catacctatt ttgcttcttt ggaagctggc gatgagaaag
     5161 cttttttcgc acacttgaaa aaatatgcaa aaaaacaaat cgtcctcttt gttcctgaga
     5221 attctcctga agtctcagaa gctattgaaa cattgtcaaa agatcgaacg gtttatcttg
     5281 tttatttcgt agaaaaacaa ctcatggtcc aagaaaaaga caagatatgt tcattgccag
     5341 gaggtgaatg gattgacgat taaacgggaa aaatggctgc gtggcgttta ctcctttgtg
     5401 atactaagtg taggtgctcc gatatttgta gtagctaatc aattgcaaaa cagctacctt
     5461 cttatcctaa ctattggtgt cctatgcctt attgtctgct gtattcctaa aaaatgggta
     5521 cgtttgctgc tttctttgcc agtaatgata ggttgtttgt ttttatattt tccttcgaag
     5581 acattttcca tattatggat cttacagttt ttttcgtcag tcacagagga attcttccat
     5641 ctatcccaag gtaaacttta ttatttgcca gaaaagacag ctttttttct cataatgttg
     5701 ctgatctatt tatttattac attgaccgtg gattacgact attggtacgc accctttctt
     5761 tctttgatgg cttacttcat gatgcttacc gtttttcgga aaaaagattt actgtacgaa
     5821 atgattgcgg tagtaactgt tttgttcgtg tatctggcag caaggcaatt tttctccatc
     5881 cggttgttgt cgggaaacac tcgattccag tcattgacta cagttctgct tatttgtttc
     5941 ttaactttta gcgctatctt gcctttatat cttccgaaag tacaccaatc tctcgaggaa
     6001 acgagtgaac cgatccgaga atatcttaat gatgaagggc tttatgacac actccatgag
     6061 tatcaattaa ccggaagtgc aagaacaggc ttcagtgaga atgatgaaca gcttggtgga
     6121 cctttatatg ataatggcga agttgttttt acagcgaacc aaaaaggaaa tggctattgg
     6181 aagatcgaaa ataaaaatca ttacaccggt tctggatgga tagaagatca ggacgcaccc
     6241 atccaaccaa tccaagaatt ccctgttgac atcacgagct accaaaccgt tatagaagac
     6301 aaagaaaaca ttacattgac cctaaaaaaa caagttttct taccttatcc ttatggaaat
     6361 actaccttga ctgatttttc attagctagt ggacaaacgc tttactattt gcctgaaagc
     6421 cagcgattca ttcctgtccc gaatgaatcg acacgttctg caactttaca aacagaaagg
     6481 ttagttttta cgagagaaga attaaaaagc agtcagttaa aagctgatga tttagaaaat
     6541 cagcagacaa atcttcaatt gccaaaaagt ttgcctaaac gtattgagga cttggcggtc
     6601 gaattgacca aaaatgaagc aactttaatt cgtaaagtcg aagctgtcta acagtattta
     6661 aaaacaagcg gaaatttccg ctattccaaa acggataccg ggcatactcc aaaagaacac
     6721 gattatgtgg attatttcct ctttgattca aaagtcggct attgtgacaa cttttcaact
     6781 tctatggtcg tccttcttcg aacacttggt atcccagctc gctggacaaa aggttttaca
     6841 aatgggctca gaacaggcac agataatcaa gggaatgagg aatacagcat tctcaatagt
     6901 catgctcatt cttggccaga ggtatacttt cctggatttg gctggcttcc atttgaacca
     6961 accccttcat ttgccaatcc aatgggttca caaccagttg ctgaaacaac cgaaaccgtc
     7021 cagcctgcta tcgaacaacc aaatgaaagc gaaaatatgg cagaaactat ttccagtgag
     7081 agatctgagg tcattccatc agaagaaaca acactcacac cagcttataa aatcgtctta
     7141 ttcagccttg gagtgtgttt atccgtcttg ttgttctttc tattgttatt cagaaaatct
     7201 ctgcgctgga caagttatct tatctatctt catttttttg cttctactaa tacgattgca
     7261 tatcaaaaac ttcttaaccc tttggaaaca ttggtaccgc gcaaacccgc agaatctttg
     7321 caggaatata gcctgcgaat agaacaagaa ttcaagctag atctgcgttt cattcgatta
     7381 actactcaat atgaagcaga aatatatgga cgacaagcag atccggtaaa attcgataaa
     7441 aaaacctatt tagaaataac gcatataata agaaaaatgg tatacaaaaa aattctgaca
     7501 aaagggagcc gcttcaaaaa ataagataaa atttctggag aatctacttc tggaatgccg
     7561 agaaccagct gattgagtat cgattactcg aaaaaaaggt tgtgacacgt tttttgtcac
     7621 aacctttttt cattattatc tgattttcaa tgtcaaagca tttagagcta caactaccgt
     7681 acttaacgac atcaagacag caccaactgc tggacttaat atgataccaa ttggcgcaag
     7741 aattccggct gctagcggaa ttgcaagaat attgtaacct gccccccacc agaggttctg
     7801 gatcattttc tttcgcgttt gcttggctag atcaagaaaa tgcaaaatat cttttggatc
     7861 gctgtttgtc aatacgacat ccgcagaatc gattgcgata tctgtccctg caccgattgc
     7921 catcccgatt gaagcacggg ctaaacttgg cgcatcattg atcccatcac ccaccatgat
     7981 tacttttttc ccttggtcaa ggtatttctg gacaacagct tctttatcat ctggtaataa
     8041 accgccataa tattcttcga tccctaaata atctgctact gcttgggcag cgtttttatt
     8101 gtcaccagta agcatgacag gagtgatttt tctttctttc aatgttcgga taaattcttt
     8161 tgcttctgtt tttactacgt cacctaaagc aacgattgca gctagatgat tttctaaaat
     8221 caggaagctg atggtatttc cttgttcttg gtaaggtttc aataatgctt gttctacgtt
     8281 taatccgaga cgctcaactt ctttttcatt aactattttc acttgttgtt ttttgactgt
     8341 tgcctctagc ccgactcctg aaagattttt tagattttca gcttgataag gcttgatttc
     8401 atgttctttc aaataattca taatgccaac agccaatgga tgattggcat tcgcttccaa
     8461 ggctcctaga tattgaagga tttcattttt attgaacgca tcatcaagta cttcgacacc
     8521 cgttacagta aattttcctt ctgttagtgt tcctgttttg tccagcatga tcacatctag
     8581 atcattggct tgctccagtg cattgcggtt tttcaaaagt aatccgtttt tagctgctat
     8641 tgatgtggaa cgagcaacaa ctaatgggat agctaaacct agagcatgag gacaggcgat
     8701 gataaagact gttaccatac gttctaatgc attaggaaga tctgtcaaga acaaccaggc
     8761 gatgaatgcc aggataccca caattaatgc gacataaaac agccattttg ccactttgtc
     8821 agataatgac tctagcttgg atttttctcc ttgtgctttt cgcaccattt ccataacctt
     8881 cgctagataa ccattttcac cagttccagt tacttcgatt tcgatcgttc catccccatt
     8941 gatagaaccg ccaatcactt tgtcattggc ttgttttttg attcctcttg attcgccagt
     9001 cacagctgat tcgtcaacaa ttgtttcacc tttcaagatt acaccatctg ttggcatttt
     9061 atcaccagac cggacgatca aacgatcacc ttcgtttact tctttcaatg aaactgtctc
     9121 ttcttttcca tctttcgtca agcgtttcac tgattctggc agtaattctg ctagtttttg
     9181 taaagcattg ctggcattcg acacagcatt catttcaatc cagtgaccta gtagcataat
     9241 aacgatcaaa gtagccaatt cccagaagaa atccatgacg tgtgtatgtg gattgagcag
     9301 atttgcgata aacgaataga cactataaat atatgcaact gtaatcccca tcgcgatcag
     9361 tgtcatcata gcaggacttt tttgtttcaa ttccatctta gctccactta aaaatggctg
     9421 accgccatag ataaatagta tagttgctaa gatcaatacg agccaatcag aaccaggaaa
     9481 cgttacttga aatggaaatt ccattcccat cattggtgaa aaaagaatga ttgggatagc
     9541 taggataagc gatagccaaa atttttgttt gaaattcccc atgtgcatgg aatgatccat
     9601 gccgccgtgt tcgtgatcca tgtgcatcga atggtccatt tgtttgctgt ttgctatatc
     9661 tccatggtta tgtcccatgt gcatggaatg atccatctga ctatggtcat gtttcatctc
     9721 catctgtttt tcatgagatt ctgtactttc tttgtttact acttcttttt tatgctcatg
     9781 ttttttctcc atatcgttcc cattcatttt tactccatcc cttctcttac tttttcatgt
     9841 gtcgatttaa gcacagggag ttcaacaata cactgacgga actaaacgcc atcgctcctc
     9901 ctgcaatgat tggattcaaa aagcctagtg cggcaaaagg aataccaatc gtattataga
     9961 caaaagccca gaaaagattt tgtttgattt ttctcaatgt caacctagac aactcgattg
    10021 tttgtgcaat ggatgccaaa ctgctattca tcagcgtcac atcggctgtt tccatcgcaa
    10081 tgtccgttcc acttcccatt gccataccga catcagctaa tgctaaggcc ggtgcatcat
    10141 tgattccatc gcctgccata ccgacttttt tgccatcttt ctgaagtttt tctacgtagg
    10201 ctgctttatc ctctggaagt acttcagcaa agatatgctt tggatcaata ccaacttgtt
    10261 taccaatcgt ttcggctgcc agtttgttgt ctcctgtcag cataaaaaca tctaatcctt
    10321 tattctggag ctgcttgatt gcttgtttga cttctagttt gatttgatca gccacggcaa
    10381 tcaacccgat cacttgcttt tcatcagcta aaaacatgac tgtttttccc tgctgttcta
    10441 attctaacgc gtgttcttgg tattcatcaa atgataggtt caattcaatt aatcgtttac
    10501 gtgtacccgc aaaatagcgt actccgttaa tcgtaccgct gattccagca cctgggtggg
    10561 ctgtaaaatc aatcatatcg tatgttgctg cttcttgcag ttttccgtat tccacgattg
    10621 ctttacctag tggatgttca gaagcttgtt ctaaagtata aaaaatagat aggacttctt
    10681 tagaaccgac tagatctgta actttgggct ttccttctgt aatcgttcca gttttatcca
    10741 aaacaatgct gtctaagtga gcagctgctt ctaatgcttc tccgccttta attaaaattc
    10801 catttcgtgc accaacaccc gttcctacca taatagctgt tggagtcgct aaacctaatg
    10861 cacatggaca cgcaatgact aatacagaga cactatggat caatgcgagt tgccaatcac
    10921 cagtgatcaa acctgtagct atgagcgtga taaacgcgat gactaatacg atcggaacaa
    10981 aaatccctga gatccgatct gcgatttttt ggattggggc tttgctccct tgagcatctt
    11041 ccaccatttg aatgatttgc gctaatactg tctgcttgcc gacttgtgta acttccatgt
    11101 gaagtagacc attcgtattg attgtcccgc caaagagcgt gtcatccgga ttcttttcta
    11161 caggaagatt ttcaccagta agcatacttt catctatcgc actgcttcct gaaataattc
    11221 gaccatctgc tggaatctgc tcaccaggac ggatgactag ttgatcacca acgactactt
    11281 cttcaatcgc taacgtttct tctttcccgt ttcttatcac ttgggcggtt tttgtttgaa
    11341 gagacatcaa ttgtttgatt gcattacctg ttttcgtttt tgctgtatgt tccaaatatt
    11401 tgccgagcaa aatcagcgtg atgatcatac tgctgctttc aaaataaaga tcttgggggt
    11461 gtccacggaa aaatccgttg taaatgctca atgcaaaggc agccgatgtt ccaattgcta
    11521 ccaatacatc catatttggt gctttcgtct tgattgcatg gtacgcacct ttataaaaac
    11581 gagcaccgac ataaaattgg acaggagcag acagcactaa ctggacgatt ggaaaatgaa
    11641 aaaagtgaac aatcgccgca tggcttccta acatcatagc aatcattgac aacatcaacg
    11701 gcaaagtcaa aaccgtactc aatataagat cgaatagcat ttttttcaaa tacgcttgct
    11761 tttcttctgc aattttttgt ttgtgggctt catcgtacaa aattgcacca tagccgatgt
    11821 tttctacgct ttggattaat ttttcagtgg tcgtcccttc atatttgaca cttgcttttt
    11881 cagtggccaa gttgactgtg gcattgacca caccaggttg tccgttcagc tctttttcga
    11941 tcctagcaga acaatttgca caagtcatac ctgtaatgac gaacgtatcc attttggttt
    12001 ctgctgttgc catcaaatca cctctgcttt ataacccaat ccattgattg cttgacaaat
    12061 cttttcggat tgaacttttg tttcatcaaa cttgaccgta ccgtttgctt ttttcaaatt
    12121 tactttcact ttttgcacgc cgtcaagtgc gcttactgtt tcttctactc ttgctgcaca
    12181 atgattgcag ctcatacctt cgattgaaaa ttgttgtttc attttttctt cctcctattg
    12241 atgttgttta cattcacatt gacctgggat acagttacat tcgatcgtat ctactggttg
    12301 cttttgttcc agttgtttca aaatctcatt gatatcttct tgagtcaaag tggcttcttc
    12361 tactagatcc gcaatcgtct ctccaatcct ttttgcacag atatgggaaa aaagattttc
    12421 cgtcgcactg cgaactgttt ccatctccga gacagctgga taataaatga atttttttcc
    12481 ttcttgttct gtccagatca cttctttttt taccaaacga cccagcaaag ttttgatcgt
    12541 tgctggtttc caatccatcg aatcagctaa gatctgcgtg atttcttggg ctgtcgtctg
    12601 tccaagtgtc caaataacac gcatgatctc ccactctgaa tcactgatct ttactggcgt
    12661 tttgactttt tccatttatt tcacaccttt cgtttacaaa tgtaatcatt atcttatgaa
    12721 tacagattac acttgtaaac aaaaactgtc aattattttt gctctctatt ttcaatttag
    12781 ttaaaaattc ttgtttctct cgtcttgttt taaggatgat cagtttattt cttgcattag
    12841 ctacttggat cagctgctgt attttcggtt cattgttttc ttcaaaatgc cagataaaag
    12901 ataaaaattc taagtattcc ctgtttagtt tctccgaaaa tgattcaggc atatctggcc
    12961 gagatttttt gtttatcttt ctttttagag aacgccaaac tactcggtag atggcgagat
    13021 aacgcggcac tttaagccaa atgatcttat ctgcttcttt aatcctttcc tctaatgtag
    13081 aagtataatt tccttcaacg atccatgacg gattagatac cataaacaat tgctgttctt
    13141 gcaaaaacca cttttttgcc tgaatactgt agtctgttgt atgccataaa aggtctagcg
    13201 gcagtagcgg aaagtcggtg atttctttga tcttccttgc gagggtcgat tttcccgacc
    13261 cactttgtcc aatcacgatg atcttcattc ttctccctca cttctctttg gaatttggtt
    13321 cgatcatacc acttataacg ccgcaaaaaa acaagggact gtgacaaaag tcgtgtcaaa
    13381 gtcccttgtt tcgaa
//
LOCUS       DACBZK010000070        13347 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.073, whole genome shotgun sequence.
ACCESSION   DACBZK010000070 DACBZK010000000
VERSION     DACBZK010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.073"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(45..1364)
                     /locus_tag="IVD66_002188"
     CDS             complement(45..1364)
                     /locus_tag="IVD66_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP6146384.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="IVD66_002189"
     CDS             complement(1361..2014)
                     /locus_tag="IVD66_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6146385.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2302..2822
                     /locus_tag="IVD66_002190"
                     /pseudo
     CDS             2302..2822
                     /locus_tag="IVD66_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2724..3442)
                     /locus_tag="IVD66_002191"
                     /pseudo
     CDS             complement(2724..3442)
                     /locus_tag="IVD66_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
     gene            complement(3566..3751)
                     /locus_tag="IVD66_002192"
     CDS             complement(3566..3751)
                     /locus_tag="IVD66_002192"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146386.1"
                     /translation="MTKALIFDFDGTMIDSEWMFYESIHHYLLKPIYWSSSAIKFLLQ
                     TINKVLGRQQNCPFMKG"
     gene            3978..5251
                     /locus_tag="IVD66_002193"
                     /pseudo
     CDS             3978..5251
                     /locus_tag="IVD66_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5358..6389)
                     /locus_tag="IVD66_002194"
     CDS             complement(5358..6389)
                     /locus_tag="IVD66_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6146387.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(6396..7226)
                     /locus_tag="IVD66_002195"
     CDS             complement(6396..7226)
                     /locus_tag="IVD66_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6146388.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(7223..8029)
                     /locus_tag="IVD66_002196"
     CDS             complement(7223..8029)
                     /locus_tag="IVD66_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP6146389.1"
                     /translation="MKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLANYS
                     DIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLAANF
                     AGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYPSMK
                     EVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALTSSN
                     VNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(8035..8859)
                     /locus_tag="IVD66_002197"
     CDS             complement(8035..8859)
                     /locus_tag="IVD66_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphatase"
                     /protein_id="HAP6146390.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(8849..9949)
                     /locus_tag="IVD66_002198"
     CDS             complement(8849..9949)
                     /locus_tag="IVD66_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP6146391.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCVSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            10127..10912
                     /locus_tag="IVD66_002199"
     CDS             10127..10912
                     /locus_tag="IVD66_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HAP6146392.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            10945..11328
                     /locus_tag="IVD66_002200"
     CDS             10945..11328
                     /locus_tag="IVD66_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAP6146393.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            11404..11535
                     /locus_tag="IVD66_002201"
     CDS             11404..11535
                     /locus_tag="IVD66_002201"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP6146394.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            11504..11740
                     /locus_tag="IVD66_002202"
     CDS             11504..11740
                     /locus_tag="IVD66_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP6146395.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(11818..12789)
                     /locus_tag="IVD66_002203"
     CDS             complement(11818..12789)
                     /locus_tag="IVD66_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAP6146396.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         4057 a         2912 c         2306 g         4072 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgacg ccttctgttg
     2101 ccaatacttt ttcttttttt taataaatgc aaacagacac cttgaaatcc tttagaaaaa
     2161 aggcttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac caaaacatca
     2281 ccctaccaaa ggagtcgctc tatggataat catactagaa aattactcgg attaacagat
     2341 aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg cgttcaagcg
     2401 cagtttatta aagggagatt ggatgactaa ccttcccatt gtgaacactg tggatcgatt
     2461 cgtattatcc gcaacggttc ctatacgaca cgtactcaga tgttgaaagt caaagaaaag
     2521 ttgactattt tagaattaaa acgtacccgt tttctatgct atgattgtgg gcagaccttt
     2581 tctgcgaaaa cggacttagt tgatgaacat catcaactaa caaaggaact gaagcaggcg
     2641 attctcatag aactgtacga aaatcaatca cgtaatctga aaatcagaag aagtaccgtc
     2701 ggctcaagcg atattggaaa ctcttactca aagattccac gacattggag ccgctcaaac
     2761 ggcattatca tcgactgttt aaacgaccaa ttagtcaaac agaaatcgtc gatgaaccgt
     2821 tgtgcacaat ggtgtcctga acgtacagcg acaccttcca tatccagagc agtcgccaca
     2881 tcacggggat ggatgccatc caaattaaaa gcaaccacgc cagtatgatg ttcaggatct
     2941 tgcggtccgt aaatggtgat accgccccga tcgcttgtaa tttaggtaaa acgtaggcaa
     3001 ccagttcttg ctcataacga tgaatattct ccataccaat ctcattcaag taatcgattg
     3061 ctcctgcaat gttcggagta ccagcttcaa atttccatgg cagctctttc catgaactat
     3121 cgtaaagatt gacaaaatct atcatttcac cgccgaattc gactggctcc atttgttcta
     3181 acaattgacg tttgccatat aatacaccga ttcctgtcgg cccgcacatt ttatgcccgc
     3241 taaaggcgaa aaaatctgca tccaacgctt gtacatcaac tgtcatatgc ggtgctgctt
     3301 gggcaccgac tggactatcc tcaactacaa cagcctgttc aaccctcagc cgtttcaagc
     3361 acaacaaata accttctgga tctggtttgc cgacctgaag atcatcgatc gtcacaaagg
     3421 aatcaatttt ttccttaatc atcggatgtg cttcaaaaaa atagtctagc tcccgcagtt
     3481 cagaattgag actactccga ttttccagtg ctgctgatcc gctgctcaaa atgttcagca
     3541 tccactggtc tcccaaccgc ttgacttatc ccttcataaa aggacagttc tgctgccgtc
     3601 ccaacacctt gttgatagtc tgcaaaagga attttatagc cgaactgctc cagtaaatag
     3661 gcttcagtaa atagtgatga atactctcgt aaaacatcca ttcactgtca atcatcgtcc
     3721 catcaaaatc aaaaataagt gctttggtca tcttctttcc cccttaccca aaacaagcaa
     3781 aagctgtgtc ctgctctctc tacagtatca gcataaaaac tgccgtctga aaagtcaaag
     3841 gtgaaagaaa tgtggcgcta taatttctag gactgatagt aaatcattct atcagtcctt
     3901 ttgagcataa aaaaacaaaa catacagaag ctccgttaga attgaatcac cacaacacaa
     3961 tcaaaggagc gttctgtatg cctgatcttc atcttatcaa actattacta ggaatcaaag
     4021 atggaaacat tcaaatcact catgtcgaga agaaaaaaat acattcaatc aacagtatcg
     4081 ttgtttctgc cacgctcatt aaaacgattc agccctgtcc tcagtgtaaa caggtgaatc
     4141 aacatgggct gatcgttaag aacggaaaga aaaaatcgct ggtccttctc aataagtgtg
     4201 cgaatcaacg gacttatctt gctttggcaa agcaacggta cctctgtcgt ggctgtcaca
     4261 cctattttac ggcgaatacc tacattgttg aaaaaaactg ttttatcgcc aaacaagtac
     4321 attataaaat attggaggaa ttgactgaaa aacaagcaat gacgacgatt tctaaacatt
     4381 gcggcgtttc ttggtcaacc gtttcgcgaa cactcgcttc tctgctcccc atgacaaacg
     4441 tgaaaataaa ttggttgcct cgctgttcat tggtagatga atttcgttca ttgaaaaatc
     4501 aagtcggtcc ctattctttt tcttgtatgg atggcgatac tgggaaatta ctggatattc
     4561 ttccttcacg taagaagaaa gatctcattt cttattttat gcaatttgaa cgacgtgcac
     4621 gtttaaacgt aaaaatactc gtaacagata tgaacgcctc ttatgctttg ctgataaaag
     4681 agtgctttcc tcatgccaaa ctcgttgtgg atcgctttca catcgtcaag cacctcattc
     4741 gcagttttaa ggatatttga ctatgagtca tgaaaagctt cgaccgaaac gatccaatac
     4801 aagccaaaca ctatcgacaa gtgaaggctt tatctcgact tctgatcaaa cgacaggaca
     4861 cgcttgttta tgataaatgg acaaaatggc gtaattttgg ttgggcctat ttaaccgaaa
     4921 gtgaagtcgt agaacgtcta ctttctactt ctgatgaact acgaatagct tatgcttact
     4981 atcaagaaat tcttcaagct ttttatgaca aagaagcgga catcttcttt cagcttgtaa
     5041 aaacaatgcc caagtcggtt ccaagagaac tgcatcatat aaaaaaagcg tttataaact
     5101 atgaatccgg cattcgttta gccttagagt tgccttactc aaatggcaaa atagaaaatc
     5161 tgcataccca catcaaagca ttgaaacgaa tagcttacgg gttaggatga gaaccagaat
     5221 tttcttaatc aatcatctga tcacttatta aacataaaaa aacatctaaa gcagaaaatc
     5281 aattctacct tagatgttct tatatcactc tatcagtcct atttgacaaa gagccagaaa
     5341 tgtttgccga ctatacacta gctttgttgt gcaaaatgct gagtatcaat ttccacaggg
     5401 attgctagaa tatctttcag ctgaatgtat aaggcatcgc taattttctc ttcccgatcg
     5461 ttcaaccgat ccactaaaat ttctttgccc tccagcgttt gaaaaacata ccgttgaatg
     5521 ttgcctaaaa taaatgattc cttccataga accggaatct taaccccctg aggaaccggt
     5581 tcaaattgaa tcagctccgg tcttaaataa taaatgcagc gattgccctt agcggaaaac
     5641 tcgtgggtat actgattcag ctcataccat tcgaaacgat tatagttgcc gataaattcc
     5701 gcaacaaatc ggctctgagg attctgatac aattccttcg aggtggaaac ctgagccacc
     5761 cgcccagctt ccatcacaaa aatccgatca ctgattcgca tcgcctcttc ttggtcatga
     5821 gtcacaaaaa tcatcgtcat ccctagcgat tgctggatag cgcgcaaatc ccgctgcagc
     5881 tgttttctaa ttcgggcatc caaagcactt aatggctcat ccagcagcag gactttcggt
     5941 tcagtgacca atgagcgagc cagtgccacc cgttgtcgtt gaccgccaga aagaaactgg
     6001 acatttttat ctgcctgctc cgtcatatcc accaatgata gcatctcaaa aaccttttcc
     6061 tgaatcacct caggactcag cttctttacc ttcaaaccaa aggctacatt ttcaaaaaca
     6121 gtcatagttg gaaacaatgc atactgttga aaaacaaagc cgatattgcg atccttcgta
     6181 ggcttatcgg caatattctc attgtccagc acaatctcac cgctctttgg ttgttccaat
     6241 cccgtgatac agcgcagcaa cgtagacttt ccgcacccgc tgggacctag taaagtaacc
     6301 agctcaccct tttcaatctg aatttcatca atagctaaaa tctgtttttc atcaaaaaac
     6361 agattgagat catgtatttc taaaaacatt ttccgtcaca actcctttaa gggcttcttt
     6421 ttcgactgct tctcttccct cgtctgctta agggacagct gttgcttttg tcgataagtc
     6481 agcataaagg tagttaaagc aattcccacc ataaacagca aatacaaaac catcacagcg
     6541 ctagccaaat ggccgttttc gttcatccgc cgcagcatat agatgcgtac cgtctgaaat
     6601 cgaccgccaa tcaacaggtt cgtcagcatg tactccccaa aaaccgaaga aaaaatcatc
     6661 agagaaacta gggtcacacc gatacggatg tttggaaaca gcacctggat aataatcgta
     6721 gacatcgggg cgcccaaggt ttctgctgca tccactaatt ccttcagatt aattaagcgc
     6781 atctggttgt taagactaag atagacaatc ggcaacgccg taataaacaa tgcacctacc
     6841 aacactacaa acattgggat accagtttca gcatacgttc gaagcaaagc cgttaccaaa
     6901 atcactcctg gtaaagcata cggcagcagg agcagctttt ccagccaacg attcaaacga
     6961 gggaaataca aatgaatcca aataatggtg ggaatcatca acaacagaat cgtcaccaag
     7021 accacacctg ctaataaaag tgagcgaccc accgcagcaa taaattccct gtccgtcagc
     7081 agctgttgga accattgcaa ggtaaaatca ctaggtaaaa gcgattttga ccatttagtg
     7141 gagctggcat acaaaatcgt tccaataatc ggcagcaagt aatacaggac aaagcagaac
     7201 aaaatcggtt ttattaactt tttcacgtct gcaccacctt gcctttcttt tgaataatca
     7261 acattgccgt taccagcagg acacctaaag cgactgccaa cgcactgcct aaattaggct
     7321 tggcgaacac atctcccgac actaaagccg caattcgaat cgttaaaaga tttacattac
     7381 tgctggtcag ggcatacgct gtttcatagg tccccatgcc attagcaaat aagatgacaa
     7441 aggtgctggc aatcgatggt cgcaaaaaag gcaaagccac cttgaaccaa gcatacgctg
     7501 atgaagcgcc cagcaattgt gcggactcca gccattcctt tttcacttcc ttcatgctgg
     7561 gatacaaaaa caagacccct aacggaattt ggaaataggt atacgtgatg gtcaatcccc
     7621 accaagaata caaattgaag tccgctagaa atggcaaaat cattttcagc acacctacat
     7681 tccccaacaa aataataaaa gagaatgcca gcggaatccc agcaaaatta gctgccaaat
     7741 tggaaacaaa ggtgattttc tcctgcaatt tagtcgatag attcattaag cataaacata
     7801 aaataaacgt cccgattaac ccaatcacac tggagctgac agcaatcagt acgctgttaa
     7861 caaaggcctg tgtgtaatat ttgttgctga aaatatcact gtaattggcc aatgtccact
     7921 ggttagttaa atcactgtgc aagctgcaca gaaccataaa aagcagcggc agcagtaaaa
     7981 atgcacagaa gataaaggag gcaggaacca gaaccaagcg ttttttcatc tctttcatcc
     8041 cctcatcaat tcttgaatgt cctgcatttt ctctgacggt gcaattccta ataaccagca
     8101 aaacaatgga gccgccagca gctgtggtac agtttgttcc ttcagctttt ggcgtttatt
     8161 tgaaatcaaa taaaaaggaa cttcacgatg tgcagccaag ctgccgccat gcagtccgtg
     8221 cgcatccatc ccgtgatccg cagtcaccac gacttgataa cctttttgca gccattcagg
     8281 aaggtaaata gccaataatc tgtccgcctg attaaccgct gctgcatatt catgagaatc
     8341 ggcggtaaat ttgtgaccga catcatcaat attcatcgaa tgtacgacca aaaagtctgg
     8401 ctgatactga ttcactaaat aatgggcatc cgcaaataaa tgcgaatcag ggtaagtgtc
     8461 ctcactataa aagatgccat gctgaatcag tcgctcctcc tgatgctgga tgcgatcaac
     8521 caaacgatta tagggggctt gattgtacaa ctcgctgtac cagtggtaag cggcggctcc
     8581 tgtttttccg ccagcttcct taactaattc aaacagcgac cactctttgg atcgctgagc
     8641 atggtaatta ctatagatgc cattttcata ggctggaacg ccggtcatca gtacttcgta
     8701 taacggacgt gaattgctgg gcagctcact ttttaccttc aataagcttg cttgctggtg
     8761 ctcaactaaa tgattcatga acccaagctg ggcgacggct gtgtcgtagc gacagccgtc
     8821 tagtataact acaatcagtt tgtcaagtct actttgcata ggtcagtacc tccgcctgcc
     8881 aaagctctgg aagctctaca gaggtcttgt tccaagcttc attgtcttca actggcaccg
     8941 ccgcttcata agcatcctcc ggcagtaatt tttcagctac ttctttaggc agctctacct
     9001 tgcgaatagg tcgcgcatag ccctttgcca aattgatttg cccttcatca gataaaatat
     9061 attcccgtgc tagctttgcc gcattgggat gaggggcatt tttattgatt aaggttgtat
     9121 acccgctaat gatggagccg tctgttggca cagttacctc aaaacgctcg gagtcaattt
     9181 ggtcacgata atttagtcca ttgaagtccc aaacaactgc cacatcgatt tcaccttttt
     9241 caagatttgc tacgctggca tcaacggtgg acaaacggcc tttttctgcc atttttttgt
     9301 agtaattcag acctggctga atatcctttt cgtcacctcc gttggcaatc gccgcagcca
     9361 atacagcaaa ttgtgcttgg ttggcaatcg tcacatcccc cacgctaact tgatagtcac
     9421 cctcttgcag ctccttccag ctagtcggtg cttgcttcac attctcttta tcggtgataa
     9481 aggaaatggt tcccgtatag cttaacaacc aatccccatc atcatccttt gcccaatccg
     9541 gaatttcctc ccaatagttg gtcttataag gtaaggttaa ctctttgctt tcagccaacg
     9601 gaccgaagct gataccgaca tcaccaatat cggcggttcc attttttcct tctgattcaa
     9661 acttagccaa ttcttctgca ctggacatat ccgtatccac gtgacttaag ccgtattctt
     9721 tttcaaggtc gttccaagtg cctacccaat ttgcccaagt atccggcatt cccaagctgg
     9781 caatctctcc ttcttccttg gctttttcta taatcgtatc taaagagtcg tctgccgcag
     9841 ccgattgctt cgttgcttca cctgagacgc agcctgtcag caggatactt actgttgctg
     9901 cacaaaataa accgatagtc atgttacgaa ttttttcatt cattttcatt cattcttctc
     9961 ccctttcgat aattccattc taacaaagct ttgtaatgag agaatcagtt tcttgaaaag
    10021 gtttcatgaa caatgtaaag gttgtatatg gtttgtaaat ttcgacgaat tcccgttaac
    10081 cttctaaagc ttttgcggta tgatagtaga aaaaaggagg ctccctatgc agtattatga
    10141 tcagcatctc cacacgtatt tttcctttga ttcagaggaa aaatttgaaa actatttagc
    10201 ctatcagccg gagtttttcg tttctacgga tcactttgat ttaaacaatc catctaccgg
    10261 aaaagatgac attccggatt atccagccta tataaacaaa ctggactctt taaaagaaac
    10321 ctattccacc aaatttctgc gaggtatcga gattggcgtt gttccaggac aagaagagcg
    10381 gatcgtggat tacctcgctc agcatcctta tgatttaaag ctggtaagta ttcatcaaaa
    10441 tggccgcttt gattatatgg acgatgtggt tttaaccaaa gatcccattc aaactaccaa
    10501 ggaatatttt gatcagatgt tgcaggtctt gacggatttt ccagaaggag atattttgac
    10561 tcactttgat tatggattac gccgcttcac cttcacagcg gaagaattcg cggagcattt
    10621 tgaggctcag ctgctaacga ttttcaaaaa ggttgttgaa cgagaattgg cgatggagtt
    10681 aaatgccaag agcttcttga aatacggcaa cgaagacctt taccgttatg ccgttccttt
    10741 gtatcaaagt gtcggcggaa agctctttac cttaggctcg gatgctcatg ttgccgaaga
    10801 ttatcagctg ggctttaaaa aaatgagtca gctgttggca gactgtcagg tagaaaagtt
    10861 gctagtcatt caaggaaaag aacgccgcct gacgccgctg ccgattttgt gattcctata
    10921 taatagaaga aagtggtgaa aaaaatgagc aacctgtggg actacaatca agaggcaccc
    10981 atccattatt taattgcgcg acattgggat gcgttgaaaa ttgaggcggt ttgccgatcc
    11041 ttgttagcag ccgttccaaa acaacaactg gaaaattttt tggtggctga cagcttgcag
    11101 cgggaaaaag ttcaggctta ttttgcagcc tttaaagatc agcctttgga atatttgcat
    11161 gcgcagtttc atctttttta tcaagtagcc gccccagatg actacaacga tttacgagga
    11221 cagctgcaat tgacctttca agcggatgaa accgcctata ccgttttatt gggaatggct
    11281 cgccttggtg atcaggcgaa ggtcgagtgg cggattttcg atatttgatg gcaggatcaa
    11341 ggcgtttcag ttgcaaacct tcctctcttt caattagaaa aaccgcagca ggaagaagtt
    11401 tgtgtgctgg tcaccgatgc tggtgaaatt cgtctccgct tatttcctga ccaagctccc
    11461 ctggctgtag ccaactggcg ctccctagct gagcaaggcg tttatgacaa cacacctttc
    11521 ggctcgtgtc attaaggaat ttgttattca aggtggcgct ttggatggtt ctggtgatga
    11581 agctgtttcc agctatgagg gctttttcgc tgatgaagtg catcgcggac tttatcattt
    11641 taatggcgcc ttggccttag gggaccacgg cccccacacc aacggcaacc agttttttat
    11701 tgtgcaaaac acaaaggcgc aggctgacct gctaatgtaa agcaagcata cttggagctt
    11761 ggaggactac cggagctgga tggtcgttat actgtttttg gacaggtata ccaagggtta
    11821 gaaatcgtag cagcgatcgc agctcagccg acaaacagtg aagatgtacc gattgagcca
    11881 gtgttcattc gacaaattaa cttcgaaaaa acatcgtaaa aagacactca ctgacttcag
    11941 caaaagctct attcttgagc tggctgcagc tagtgagtgt ctttcattta tccataagat
    12001 aaagcttgga ttcaataaat aaataaatgt tttggttaaa gctgtgacca gcaaatgagg
    12061 aaccgtgcga gccagttgat ctgccaatgc aaacatttct ttaggtgaag gcgctggcgt
    12121 gtctgccaac ggatactcca gtcccaatgc ttggtaaccg tgcataccat agcagtggta
    12181 cggtagtaat tctaacggta cgaaccgatc aagatctgcc acaaaacaag caatcgtcag
    12241 cagctcggtc aggttcatat tgatacctgg aaccacagga actcgaattc gcacttcgca
    12301 gttaggatac tcaattaaaa agcgacgaat attcttcaaa atttgttggt tatctaagcc
    12361 ggtccattgt ttgtggagct tgctggtaaa catttttaca tccacaaaca atgtatccac
    12421 atagggagct accttttgga tttcattata agcaccacaa aagctggttt ccagtacggt
    12481 attgattcca atgtatttcg atttttgcaa aatttcttta gcaaaatccg cctgaaccag
    12541 tgcctcgcct ccgctaatgg tcactccgcc atccgagtga aagtaaaaaa cagcatcctt
    12601 ctcaatctca tccattacct cttcagcggt catggtctgg ccaaatcctt tttcaatctg
    12661 cttgctttgt gattcgggaa tcgaacacca ggcacagcgt aatgggcagc cctttaaata
    12721 aacaacggtc cgtaaaccag caccatcatg tagagaaccc tgttctattc ttaatactgt
    12781 tccttccata tagatttttg aattacacac tagtttaaac taaaacacac aaggaaaaac
    12841 ttaccattta atcataaaat tagctcatat aaatatacta ggatgtaaaa tagactggtc
    12901 aaaatctggt caaaaaagag gactaataca ggtagtcctc ttttttgtta ttttaatatt
    12961 ctaaatcatt ttttattggt ttattccctt attcgatgta gactcaaatc actatatcac
    13021 tagatatcaa acggcgtcat acggaatcaa aaacatcaaa tttgacctgt taaatggtca
    13081 ttgaataaca ttcaaaatca ataaaacgga gtcagacacg gagtcaaaaa cgctgagagt
    13141 aaaaaatata tacagccttg taggtaaagt accacagggc tgtatatttt ttatttcaga
    13201 ttaccttaaa tgattccatt tactttttat ctcatttttt cctactagtt agtatcaaat
    13261 actctcctat tttctcaata aactattttt ggatacatgg tatctgaaac agctaaaacc
    13321 ttgtcattac agcaaaaaat cacgtta
//
LOCUS       DACBZK010000071        13052 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.074, whole genome shotgun sequence.
ACCESSION   DACBZK010000071 DACBZK010000000
VERSION     DACBZK010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13052
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.074"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(77..149)
                     /locus_tag="IVD66_002204"
     tRNA            complement(77..149)
                     /locus_tag="IVD66_002204"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="IVD66_002205"
     CDS             530..1099
                     /locus_tag="IVD66_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HAP6146397.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="IVD66_002206"
     CDS             1086..1946
                     /locus_tag="IVD66_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP6146398.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHAGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="IVD66_002207"
     CDS             2136..2840
                     /locus_tag="IVD66_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6146399.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="IVD66_002208"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="IVD66_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HAP6146400.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="IVD66_002209"
     CDS             4677..5993
                     /locus_tag="IVD66_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146401.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="IVD66_002210"
     CDS             5994..6863
                     /locus_tag="IVD66_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146402.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="IVD66_002211"
     CDS             6918..7727
                     /locus_tag="IVD66_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP6146403.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="IVD66_002212"
     CDS             complement(7830..8459)
                     /locus_tag="IVD66_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HAP6146404.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="IVD66_002213"
     CDS             8629..9921
                     /locus_tag="IVD66_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6146405.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="IVD66_002214"
     CDS             complement(9997..10659)
                     /locus_tag="IVD66_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP6146406.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /locus_tag="IVD66_002215"
     CDS             10884..11168
                     /locus_tag="IVD66_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HAP6146407.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="IVD66_002216"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="IVD66_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HAP6146408.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4338 a         2255 c         2825 g         3634 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacgc tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    13021 tgtttagagc gtgagacaaa agtgttcttt ac
//
LOCUS       DACBZK010000072        12989 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.075, whole genome shotgun sequence.
ACCESSION   DACBZK010000072 DACBZK010000000
VERSION     DACBZK010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.075"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(88..1668)
                     /locus_tag="IVD66_002217"
     CDS             complement(88..1668)
                     /locus_tag="IVD66_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HAP6146409.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLYQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2069..3445)
                     /locus_tag="IVD66_002218"
     CDS             complement(2069..3445)
                     /locus_tag="IVD66_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAP6146410.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(3573..4691)
                     /locus_tag="IVD66_002219"
     CDS             complement(3573..4691)
                     /locus_tag="IVD66_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP6146411.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            4833..5267
                     /locus_tag="IVD66_002220"
     CDS             4833..5267
                     /locus_tag="IVD66_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6146412.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5345..5878)
                     /locus_tag="IVD66_002221"
     CDS             complement(5345..5878)
                     /locus_tag="IVD66_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HAP6146413.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(5972..7150)
                     /gene="mutY"
                     /locus_tag="IVD66_002222"
     CDS             complement(5972..7150)
                     /gene="mutY"
                     /locus_tag="IVD66_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HAP6146414.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7143..7940)
                     /gene="recX"
                     /locus_tag="IVD66_002223"
     CDS             complement(7143..7940)
                     /gene="recX"
                     /locus_tag="IVD66_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HAP6146415.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8047..9429
                     /gene="rlmD"
                     /locus_tag="IVD66_002224"
     CDS             8047..9429
                     /gene="rlmD"
                     /locus_tag="IVD66_002224"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAP6146416.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(9603..10181)
                     /locus_tag="IVD66_002225"
     CDS             complement(9603..10181)
                     /locus_tag="IVD66_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin-binding protein"
                     /protein_id="HAP6146417.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            10503..10973
                     /locus_tag="IVD66_002226"
     CDS             10503..10973
                     /locus_tag="IVD66_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HAP6146418.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(11081..12307)
                     /locus_tag="IVD66_002227"
     CDS             complement(11081..12307)
                     /locus_tag="IVD66_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HAP6146419.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT         3840 a         2621 c         2186 g         4342 t
ORIGIN      
        1 cgtcacggct ctaaacaaaa tatgagaggc tgtttttgtt tggctattct tattacttga
       61 tgcagggcag cttgtgtcaa gacttcttta catcaaactt tttaatttta cattgggata
      121 tttatccgca aaccagcgtt ctgcaaattg gttctcgaat aagaacaacg gttggtcgaa
      181 acggtcacga gccaagatat tgcgacttga actcatcttc tcatccaaat cttctggatc
      241 gatccagcga gcgattttgt gtcccattgg agacatgatt acttcggcgt tatactcatt
      301 taacatacga tattggaata cttcgaattg tagctgacca acagctccaa tgatatattc
      361 ttccgttaga tatgttttat aaagctgaat cgctccttct tgaactaatt gatagattcc
      421 tttgtggaag gatttttgtt tcatgacatt ttttgcagtc actttcataa acagctctgg
      481 agtaaatgaa gggagttctt cataagcaac ttttagtttt ccttcgaaca atgtatcccc
      541 aatctgataa ttgcctgtat catatacacc gatgatatcg cctgctactg ctttttcgac
      601 gttttctctc gaatctgcca taaattgtgt gacattgctt aatttcagtt ttttatttgt
      661 acgttccaac cagacatcca ttcctcgttc gaatgttcca gaacagattc ggacaaaagc
      721 gattcggtca cgatgggctg gattcatatt tgcttggatc ttgaatacga aacctgaaaa
      781 ttcttcctca taaggactta ccatctgatc atcttgtgtt ttgtgtccat aaggagctgg
      841 tgccaattca acgaaagtct ctaaaaaagt ctgtacaccg aagttagtca atgcagaacc
      901 aaaaaatact ggtgtctgat cgccacgagc aattttttct tgattaaatg catctccagc
      961 ctctttgatt agttctactt cttctaagac ttgttcatat aaggaatttt cagttagagg
     1021 atgattttcg ggaagcagtc catcttcatc caattctact aatcgttcat cctgataatt
     1081 ttccggacga taaaactcta cacgattatg gtagatatca taaagacctt ctagcccttt
     1141 acccataccg attggccaat tcatcggata agattcgata tctaatagct cttctaattc
     1201 ttctaacaat tccaatggtt cacgaccatc acgatctagt ttgttgataa aagtaaatat
     1261 cgggatgcca cgttttttta caacttggta taatttcttt gtctgtgctt cgatcccttt
     1321 tgcactatcg attaccatga ccgcactatc cacggccatc aaagtacgat aagtatcttc
     1381 agaaaaatct tcatgtcctg gtgtatccaa gatatttact cgtttccctt gataatcaaa
     1441 ctgcataaca gaactagtaa cagaaatccc acgttgtttc tcgatttcca tccagtctga
     1501 tttggcaaaa ttacctgttt ttttgccttt tacggtcccg gcttgacgga tagccccacc
     1561 aaacaatagt aattgttctg taatcgttgt tttcccagca tccggatggg aaatgatcgc
     1621 aaaagttctg cgattgtcca cttgttgctt taattttgga ttattcataa cctaactcca
     1681 tttcttccat tcaattattt atattttctc taggcacaga ttgtccgatc tcttaaagaa
     1741 agacaatttc atatagggct gtgacaaaag ccgtgtagca gtctcttttt ccgagtaaac
     1801 ggcgttctag agacagccta tcagcaataa gcccacccaa gccaaaaata cgaaaagctg
     1861 tttttgcttg gctgctctta ttacttaatg caggatagct ttttcacaac ctttgtcaac
     1921 tactacaact gaatcagtat agcatggatt cagcgaatga aaaagccacc aaaccataag
     1981 agtcaaatat ttttttgtca gctgactaaa agaaaagacg tgttgcttgt ttattcaagc
     2041 aacacgtctt tcataaccaa gtttccaatt atcttcttgg ctcgtcatct tcgaattctt
     2101 ttctgaagta tcttcgttct tcttcaggtt ccgcttctgt ttcttccgga tcatgaaaaa
     2161 tgacacggat tttaaggatt cgagaacctt ccatttcttc agaaaccagc gtaatattat
     2221 cgacatcaaa cgataacttt tcgccttcat ccggaatcat gcctaatgct gtaatcaaat
     2281 aaccagccat cgtatctaca tcactcatat gcagatcact gtcaaaagct tcattgaact
     2341 catcaatcag catacgtcct tggatgatat attcgtgttc atcgattttt tcataaagat
     2401 tctcaacttc atctgattca tcatcgattt ctccgacgat ttcttctaaa aggtcttcta
     2461 gtgttgctaa cccaacgacg ccgccatatt catctaataa aatagccatc tgattctgcg
     2521 tctttttcat ttcatataac agatcatcaa taaagaccgt ttcaggaacg aataaaggct
     2581 cctgcatgat tttcttgata tctaaattat caaagccgaa tttatgggca gcttttagta
     2641 aattctttgt atgaaggatt ccgactactt tatctttgtc ttcgttataa acagggattc
     2701 ttgaatagtt ttcggataaa acttcattca cattttcttc cacagtgtcg ttgatatcaa
     2761 tcataaatgc atccgttcgt gggaccatga cttctcgggc aactttcgta tcaagagaaa
     2821 aaaccccttg gagcatttct aattcttcat tattcaatac gccttcgttt tcaagcatat
     2881 aacgcatttc atctctggtc atttttgaat cttcatcatc aaaagtcatc ggcgtgatac
     2941 gcgccaataa acttgtggaa gcagaaagca gccagacgaa gggcttagct actacaccaa
     3001 tcaagcgtat cagccctgaa gtgaactttg cgacttcttc tgatttattt aaagcaatac
     3061 gtttagggta caattctcca aaaacaatcg atacataggt caaaatagcc agcacaatga
     3121 tatttgcaat attttttgcc gctgtgccgc cacctaatac cggagctaac cgttccgata
     3181 aagtattagc tagtgaagca ccagacaaaa tgttgaccaa agtgattcct acttggattg
     3241 tcgataggaa attatttgga ttctgcaata tttttaaaag cttttgagat ttcacatctc
     3301 cttcatcagc tttttgctcg attcgattct tattgatcga aacaacagca atttcggaag
     3361 ctgctaaaaa agcattgatc aatgtcaaaa cgatcaataa taaaatctgc gctaacagcg
     3421 actgactctc agggtcagca ttcataatcg cattctctcc ttataaaatt aatttttagt
     3481 ttacgataga aaaaaacgtg gcactatagc cacgttaaaa tggtatcaca aagcaatttt
     3541 ctttgcaata aaaacaagtg tactaaaact acctacgagg tcgtagcaat tttcttcttg
     3601 ttttcatttt gcttgtcttc tttgacgatt ttgattatat aggaaatgat cgtcttgcag
     3661 attgcgtaaa aaggaacacc taagaagata ccaagcaatc cggcaatatt tccagctact
     3721 agaagaacga taatgatcgt taatggatgg attttcagtg atttcccaat tacattagga
     3781 taaatgatat tcccatccaa ctgttggacg attagcacaa ccacacaaca aagtaatgct
     3841 tttaccggat cattgaagac tgttactaga aatgcaggtg ctagtcctag ataaggtcct
     3901 aaatatggaa ttaggtttgt caatcccgca atgaccccaa ataagaaagc ataatccaca
     3961 ccaattacca tatatcctaa aaatgtgaag gtaccaacga ataaacattc gattgcttgt
     4021 ccgctaatgt aattagccaa tgttttattc agttgcccca ataactccac aatttggttt
     4081 cttctttttt ctgggaaaaa ctgttggatg tttggcacta gtttttctcc gtctttcaac
     4141 atatagaaca agatgaatgg tgctgtaatg attactacgg ttgccgaagc gatcgttcca
     4201 acgatcgaac ctaaactatt ggatactcca ctaaggaatt gctgaatgat tgtcccgtaa
     4261 gaaatgtcta attgctcaaa atatttattg atatctactt ccttgaacaa aggcaattcg
     4321 gctacctctt ttaaccagct ttctacctgt ttgatgaaat caggcatatt agatgccaat
     4381 gaggaaattt gctgtactag acttgggatg acactaagta aaatccaaat aattgctgca
     4441 actaaaagga gcagcacaat tgcgacagcc catattcttt tgatttttgc tttcatcaac
     4501 agcttgacaa taggattcaa taaatagtaa agaaagcctg caatcagtac aggtgcaaat
     4561 aacgtggaaa aaaatgtccc gatcggttcg aaaataaagt ttatttctga tgaaatcatg
     4621 atcaatgcag ctatgatcaa taattcaagc gaccaaaaca ttagtttaga ctgtctaagt
     4681 ttttcaaaca atagatttcc tcctttcttt cttactagta tatattatat tcgttaaaaa
     4741 ttcttttatt ctttttttat ttttgaaaac ttgccatact ttttatttgt tttattttcc
     4801 agtatactat acgaaaggaa ggtggctaga ccatgaaagt tgtacaaaca aaagatacaa
     4861 tgagcaatat ttacttagat gctgtacgga tcaggcatca agtttttgta gtcgaacagg
     4921 gtgtgccttt gtctcgagaa atagacaaag atgaagccca ttgtatccac ttcgtcctgt
     4981 actcagataa aaaagaaccg caaggaactg tacgtctttt gcctttagaa aacggaaaaa
     5041 tgaaattaca gcggatggcg attctttctg aatacagaca ccaagggtta ggaaaaatat
     5101 tgattgaaga agcagaaaac tttgctaaga atcaaggcta taatacgatt ttattagggg
     5161 cacagtccac agctgaaact ttttacgaaa aactaggata tacagcttac ggcgatcctt
     5221 ttgaagatgc tggcatgcct catatttata tgaaaaagac tttataaaaa tttatttcga
     5281 aaaaagcaaa aaacagcaag cttttgagaa aaatctctca ctggcttact gttctttttt
     5341 gtgtttactt acgcgacaat tgcttgtaac ggttatacca aatatcaata tagccttccg
     5401 agaacgggcc atctccatta ttgatccagt caaccagaat cttcacattt tcttttagga
     5461 tgaagtcaat atcgttcggg taattcatca ttttgctgtg catctcatat tcatcgacat
     5521 ccaatagtcg tttctcgccg tcaggaaata ccttgatatc caagtcatag tcgatatatt
     5581 tcaaggcctc atcgtccagc aaaaaaggtg aagctagatt acaataatag gaaaccccct
     5641 tttctctgat cattgctatt acattgaacc agtatttttt atgaaaataa acaatcgctg
     5701 gttcgcgcgt tacccatcgg cgtccatcag attcagtgac taatgtgtga tcattcacgc
     5761 cgatcataga gtgttcgctt gtttttaata ccatggtatc tcgccacgtt cgatgcaatt
     5821 tgccgtcgtg cttgtaactt tggatcgtca caaactctcc ttcttttgga actcccatag
     5881 caacccttcc ttaagcagca ttttgtgctt tgtgtttggg tgttcattac accgacatca
     5941 taattattat atcaataaaa atgagctttg cctagaaagg attcctattg tttcgatttt
     6001 tctctaactg atctaccagt ttcatttgga ccttaggaaa aacgaccgaa tcaaatgcat
     6061 caggcttcaa ccacttcgaa gttttgttct cggtaaattc ttgttctgct ccctcggttg
     6121 cccgtccgta aaaaaggaga acatgccatt tcagatgact aaaaatatga gtaacttctc
     6181 ctaaatgtcg tgtctgccaa acaaagagtt cctgcttttc aaatgggaga ttttgctctt
     6241 cttctgctac taggtcatca aacagatcga tttctggctt tgtttcccat tcttttttca
     6301 atcgctcata ctcctcttgt gtcacttcca tcattggaaa tgtccacata ttcgccagca
     6361 atttttggct atctctttct tcaaaataat acgctccaga atgattttga agagctgcac
     6421 tgatataata aacgtctttt ggctttgctt tttttgtttt tacaggaaaa ctcgtttgga
     6481 ttcctcgttt gttagctaaa caaaaggctt ggatcggaca agtctcacac tttggagaag
     6541 ttggtgtaca gatagctgaa cctagatcca tcattgcttg gttgaattca cctggatgct
     6601 tttcatcaat gattttccgc atcgcttcat caaagatttt cctgctagaa gcttttgcga
     6661 tgtctgcttc aatgcaaaac aatctgctga ctactcgcat cacgttgccg tcaactgcag
     6721 gttctggaag tccaaatgcg atacttgcaa tcgcgcctgt cgtatatggt cctattccct
     6781 tcaatgagct aatttcttca ggcgtttgcg gcatttcccc atcaaattct gacatgatct
     6841 gtttagcagc agcttggatg ttccgggctc ttgagtaata accaaggccc tcccatgctt
     6901 ttaaaagctt ttcttctgga gcatttgcta gctcttcaat tgtaggaaac cattccatga
     6961 aacgataaaa ataatcgatc actgtgtcta ctctggtttg ctgaagcatg atctcagaga
     7021 tccagatacg ataaggatca cgattatagc gccaaggcag gtttcttttt tcttgttcat
     7081 accattgaat gaactgatct tgaaattctt ttgtttcttt atctgtccat ttttcccatt
     7141 ctttattcac tttcctcttc cttttccgta atgaatcgct ggatcatatc caaatcaaat
     7201 cctttttgat ataagctttg ctttactttt agatttcttt ttttaggttc aaaccttaaa
     7261 tttcttcgcc atagtttatc tccttgtttg actaaataat catattctat ttcttgatct
     7321 gcttcttgcg gaagatcagc tatcgcttgt tggatcactt cttgagaaaa gcctttcgtc
     7381 atcaatgttt gttggatttt tctcaataat tctttttggc tttttccgtg attttttcca
     7441 aacgcttttt cggctgtctg atgtgcattt tgaacttggt cttcaaatgt atattggctg
     7501 agcgcttgtt caatgatttc aggtttcaaa cctttttgct gcatctgctg cgctaatttc
     7561 tttggtcctt tgtcacttaa gcgcatattc gtgcgcacat aactttcccc atagaccaaa
     7621 tcatcgacaa ggtccaattc ttttaagcgg gctacgattt tatttcgatc ttcttgaagg
     7681 atttcctttt cttttaagta tgttcggatt tctttttccg atcgcaactg ataacttaag
     7741 taattcattg ctaggtgaaa accgaaatca gctccgctac tcttcttgat ctcttggata
     7801 gtttcttcgt ctaattcccg tccttttaat aatcgatagc gtactaatac atcttcagat
     7861 acttgtaaag cttctccttc agataaatct acgcgataga aagggccttt gcctttactg
     7921 attctcgtaa cggttaacat aaacatcctc ctcgaacata tattctctat cataccacag
     7981 aaaatccccg taatcaggta ttatatgtta gaataaacca cagaaaaaag aaaaagggag
     8041 atacttatgg cagaaacaat tgtcaaaact ggacaaacgg ttcctttgaa aatcaagcgt
     8101 ttaggcataa atggtgaagg aatcggttat ttcaaacggt tgatcatatt tgttccatat
     8161 gcactaccaa aagaagaagt actagtgaaa atcacgaaag caactcctcg ctatgcagaa
     8221 ggagaattaa taaaagtcaa aaaaacaagc aaagatcgcg tagtggcacc atgtcctgtt
     8281 tactatgaat gcggtggctg tcaattacaa cacttagctt atcaagctca attggatttt
     8341 aaaaaggatc tgcttttgca agcattggaa aaattcaaac cagcaggctt tcgatcttat
     8401 caacttttgc cgacgatcgg gatggatgag ccttggcatt atagaaacaa agcacaattt
     8461 cagttacgaa aaaataagca gactcaaaaa attgaagctg gtttatacga agcaaactct
     8521 catcagttag tccctataac agactgcttg gttcaagaac ctcgaacaca aaaagtaatg
     8581 aatactgttg ttcaactatt gaataaattt gatgcaccca tctatgatga acggacaaac
     8641 agtggaatct tccgcacaat catggttaga atcggtgtta aaactgggga gttacaagtt
     8701 gtttttatta ctcgcagtaa aaaattcccg caaaaaaacg caatgatccg tgagatcaat
     8761 gaacgactgc ccgaagttgt ttcaatcatg caaaatgtcc aggcacaaaa aacgtctctc
     8821 gtgatggggg atgaaacgat ccacttatgg ggaaaagaag ccattgaaga acaaatcaat
     8881 gaagtgactt tcgatctttc tcctcgtgcc ttctttcaac tcaatcctca gcagaccgaa
     8941 ttgctttatg gcgaaggaat caaagcatta gatgtccagc ctaatgaaac gatcgtggat
     9001 gcttattgcg gagttgggac gatcggctta agtgtagcaa aacaagccaa agaagtacgg
     9061 ggaatggata ccgttcctca agcaatcgct gatgcaaaaa aaaatgcgga aagattagga
     9121 tatcacaaca ctcgatatga agtcgggaca gcagagcaag ttctgcctaa atggttgaat
     9181 gaaggttttc agcctgatgg tatcatcgta gatccaccac gtacgggttt ggataacgca
     9241 ttgatccaat cattattgaa ataccctcca aaaaaacttg tttatatctc ctgtaatgtt
     9301 tctacacttg ccagagatct ggttaattta agtaaaaagt tcaagattga atatttacag
     9361 tccgtcgaca tgtttcctca gactgcacgt tgtgaagttg tcgtgaagat gacgagactc
     9421 gctgactaaa tgaaagaggt tgtgaaaaag tctgccctgt atcaagtaat aagaacagcc
     9481 aaacaaaaat agctcttcat gttttatgaa tactgtactt gtgaccgaag agttaacagg
     9541 aggacactat ttatttaaaa aaagggttgt gacatagttt ttgtcacagc cctttttgat
     9601 tattattgga tattcacgtc tatcacttga taaaatgcat ttgtcgtatc gctgatattc
     9661 catactgcta aaatcacatt atatcctttt cgatcctgcg gaagtgtgat cgtttggttg
     9721 actgtttttg gtggaacagt tgctttgtcg tctatttttg tgatcaattc aaaatcacta
     9781 aatttcaaag gttgattagg attccaagtt ggtttggtaa tgtagtaatc ccaagtactt
     9841 gtccgatgtt gtgctgttaa attccaagta atatttaatg ttcctggatt aaccatgttt
     9901 ttatgccatc tgttagatgt ctgttcatct aaaggctcaa agccgctgac tcctgcacta
     9961 gcaatttttc catcaatgaa tgtatttttg gtagcttcga tactttgcgg ttcccattgt
    10021 gctcttccga cattttgatt taagtttcct gctgctgatg ttcctaggta tgcacggctt
    10081 cctggagaag taatataacc atgcgcaaaa cctggaatgc taaaaccgaa caaccctaaa
    10141 ctaactaacc caataaacaa taacgtacta atctttttca tgtagaaacc tccttcattt
    10201 gataaccaca ttgtaaacgc tttattgtat taacacaaac attatgcttt tataatttta
    10261 tgttgaagta aaaaaggtga aaaaagtaag atgcagatta taacagaagt agacgagaaa
    10321 agtacaaata gaaaacatga gaatcaaatc atatgatctt tttcaaaaac atcattcata
    10381 taaacaaatg ttcaactttt taataacaac aattatcaat ttttttctta cttcacaaac
    10441 taaatacagg tcttgctgtg agccttcatg gtaaactaat attatagaaa ggagttagta
    10501 aaatgaagat gataaaagat attcgttttt gggtttgtgt tataggaatt gtcatattag
    10561 gctttttatc agggttgctt agcggaaatc ccggaaaata ttactattct ttgcaacttc
    10621 caccatttgc accacctagc tggatatttg ggccgatgtg gaccttactg tatatattga
    10681 tgggtatttc tctttatttg ttacttaatc acaacaacaa aaaacagcga aacaatcttg
    10741 tcggtctttt tgtgattcag ttcattttta attttatatg gtctgctcta ttttttaatt
    10801 taagaaatat tttcattgca gcaatcgata ttacactttt agttattttc ttgtcagtgc
    10861 ttatgtatca gttgtggctg catcatcgcc tggcaatgtg gctcatgatt ccttattatt
    10921 tatgggtact attcgcaact ctattgaatt attcaattta ttttttaaac taagcgctaa
    10981 aaagagacgt cctgtaattt aacacataga aaaagtgcca cctaagttag attttttgtc
    11041 taatttaggt ggcactcttt attaaccaaa ctattttttt ctagtaccca cttgttgttc
    11101 catactcatt attctggtca taaccataac cattttgttc ctgtccagcg taaggatcat
    11161 aactttgagt atcttgactt ggtgtatagt actgacttgt atcttctgtt tgctgataat
    11221 aggtattcgg atcttggtac tgatcatatg tgttttctga ataggaagaa taatcggtgt
    11281 acccttcact attcgatcca tcaccgtttg tcgaatcgcc atcttccgaa tcatcaaaga
    11341 acatcattga agcattctca tttttcaaat taggtaatgt atcgcttgtt tttatattta
    11401 attgtttctt cagttcattt tggatcgaaa gaagatcatt ttttcctaaa atttgatagt
    11461 agatatcatt gatcatttgt ccttcgcctt gcaactggtc ttgtttgatt gtttcaaacg
    11521 ccggggtgta gttcgtcgct acatcaagca tgtcatccca atctaagtcc gtcgtcacat
    11581 tgttctcaac tgcttttaaa atttttctat aattgcttac gccatctaaa cttaaaactt
    11641 tattgacgat tttcgtcact acttcccgct gacgacgttg tcgaccgata tcgccttctg
    11701 gatcttcgtg tcgcattcga gaataggcta aacctttttc tccattcaat gtttgttcac
    11761 ctactggtac atggacacca tccaaagtaa agtcaatttt attattcact ttgatgccac
    11821 cgaccgcatt gatcaaatct tccatgccat ccaaattgat cgttacataa tgatcaatag
    11881 gaatatcgag cagttgctca attgaatcca tggccatttc gacaccacca aatgcgtagg
    11941 catgatttaa tttatctacc gttccataac ctacgatatt cgtataaata tctcggtcca
    12001 aactgatgat cgttgatttt ttttgtttcg gattaactgt tactaccatc atcgtatcag
    12061 aacgtccttg ttccgttctt cctaatccac cggtatctaa acctaatagc aaaaccgaaa
    12121 aaggttcttt gtcatcaatg cttactctct cagaacgttt ggaggatatt cgattagagt
    12181 ttttagaaat tttgtttact gtttggctcg cttctcccat aaatctgatt ccgtatgctg
    12241 ataatccggc aatcagcaaa acgaataccc ctaacaaggt taatagaact ttttgccatc
    12301 gcttcataat acacctctgt ttcacatttt ctaaaatatt gtctcatata actgttcaat
    12361 cagcaaattc actttttaat cataagaaaa ctttaaaaaa catttttgtg taacgattat
    12421 tattttttaa aatttctcaa aattcttaac tatcatacca taccgtgaaa aagatcgaaa
    12481 gaccgaatac acgcagttcg caatcgtttt atcttttttt atgtattttt tccagaaaaa
    12541 gcgaacaaca aggtattttc caaataatcg tgcagtaaaa tgatcgcaca tacctttccc
    12601 atctttttaa cagtctttgc ctaccgttca gattatcatt cgatttcacg acaatttctt
    12661 cctatgactg gtccttttgt taaacccatc ttctattcgt tttatttcca gctcactgca
    12721 tggctcttaa aatgactcga actagtgatt gcattaccat catcttttaa tggatagata
    12781 tgctcctctt caaagtaaaa cgattttctt ttaaagtaat agaattgaca tggtaatgag
    12841 tatgtatact agtggtttca caaatggtct tttattcaac atccaaaaac tgaaatttct
    12901 ttaaaatcca ttactaacga agaaaatgtt ccttgcttga taattagtta ggacatgtca
    12961 agtgaacaaa tgcatttact tagccaaaa
//
LOCUS       DACBZK010000073        12710 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.076, whole genome shotgun sequence.
ACCESSION   DACBZK010000073 DACBZK010000000
VERSION     DACBZK010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12710
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.076"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(162..2159)
                     /gene="tkt"
                     /locus_tag="IVD66_002228"
     CDS             complement(162..2159)
                     /gene="tkt"
                     /locus_tag="IVD66_002228"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAP6146420.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2261..2512)
                     /locus_tag="IVD66_002229"
     CDS             complement(2261..2512)
                     /locus_tag="IVD66_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HAP6146421.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2659..3282
                     /gene="lexA"
                     /locus_tag="IVD66_002230"
     CDS             2659..3282
                     /gene="lexA"
                     /locus_tag="IVD66_002230"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HAP6146422.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3462..3680
                     /locus_tag="IVD66_002231"
     CDS             3462..3680
                     /locus_tag="IVD66_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146423.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3969..4481)
                     /locus_tag="IVD66_002232"
     CDS             complement(3969..4481)
                     /locus_tag="IVD66_002232"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HAP6146424.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="IVD66_002233"
     CDS             complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="IVD66_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HAP6146425.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6934..7368)
                     /locus_tag="IVD66_002234"
     CDS             complement(6934..7368)
                     /locus_tag="IVD66_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HAP6146426.1"
                     /translation="MKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPLILV
                     IIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQREFRN
                     ERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7378..8166)
                     /locus_tag="IVD66_002235"
     CDS             complement(7378..8166)
                     /locus_tag="IVD66_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP6146427.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8163..9104)
                     /locus_tag="IVD66_002236"
     CDS             complement(8163..9104)
                     /locus_tag="IVD66_002236"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HAP6146428.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9281..9868)
                     /locus_tag="IVD66_002237"
     CDS             complement(9281..9868)
                     /locus_tag="IVD66_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HAP6146429.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10089..11402)
                     /gene="obgE"
                     /locus_tag="IVD66_002238"
     CDS             complement(10089..11402)
                     /gene="obgE"
                     /locus_tag="IVD66_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HAP6146430.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11690..12700
                     /gene="gap"
                     /locus_tag="IVD66_002239"
     CDS             11690..12700
                     /gene="gap"
                     /locus_tag="IVD66_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAP6146431.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
BASE COUNT         3513 a         2847 c         2260 g         4090 t
ORIGIN      
        1 ctcaagaaac acaaactaat ccgaagaatt ctttgttttg tcatttaaat gtaacatagc
       61 cgaaaacgaa aagtaatatt gatttattct tctaacacat aaagaacagc tgtctccaac
      121 ttgcagacag ctgttcttat cagtcaaaca attgcttgga tctatgatag ttgattgtac
      181 gtattcacga cattttctac tgtaaatcca aattcttcta aaattttagt gccaggggca
      241 gatgcaccga aatgatcgat tgtaatcgtt gcgccctctg ttcctacgta gcgttcccat
      301 ccaaatgatg cagcagcttc gatagccaca cgtttcttca ctgatttagg aagtacactt
      361 tctttatatt cagaagattg tttttcaaag aggtcaaagc ttggcataga aacaacagaa
      421 acatctttgc ctttttcagc caattctttt tgagctttca cagccaaatc aacttcagaa
      481 cctgttgcaa tcaaaatacc ttctggtgtt tctccttgtg atggagaaag aacatacgcg
      541 ccttttttca ccatttcatc tgctacttct tttgtagaag gcaatactgg aaggttttga
      601 cgactcaata caaggatagt aggcgcatct gttgtctcca tcgctacttt ccaagcagca
      661 cgtgtttcat ttccgtctgc cggacgaatc acttgaacac caggcatgca gcgaacagat
      721 gctagttgtt caatcggttc gtgcgttggt ccgtcttctc cgacagcaac cgagtcatgt
      781 gttaagacgt aaacaacagg agtatgttgg attgctgcta aacgaactgc tggtcttaga
      841 taatcgacaa agacaaagaa tgttccaccg tagatacgag ttccgccatg aagttggata
      901 ccattcatag ccgaagccat tgcaaattcg cggacaccga accagatgtt gcgtccttca
      961 taatgttcag gagtgaaatc tttatctgca gccaccattg tattattgga acctgacaag
     1021 tccgctgaac caccccagaa gcttggtata gctttcgata attcttggat gacttcttta
     1081 cttgaaacac ggcttgcttg actgcttcca acttcataag ttggcaattc tgcatcccag
     1141 ttttctggta gtttgccatc aaaagcatct tcaaattgtt gtgctaattc aggataagct
     1201 tttttataat tggcaaacat ttcattccat gcatcttcag ctttttgtcc ttcttctatc
     1261 atcgtttgat ggaagcgggc agctacttct tctggaacag tgaaatctgg atactcccaa
     1321 ccataaactt ctttagccat cttgatgcca tcttcaccaa gaggagcacc atgaacagca
     1381 gatgttcctt ctttaggagc accatagccg atgactgttt ttacttcgat caatgttggt
     1441 ttgtctgttt cagcttttgc ttcttcaatc gctttagaga ttgcttctag gtcatttccg
     1501 tctttcacta agatatgttg ccagccatat gcttcatagc gagcaccaac gttttctgtg
     1561 aaagcttttg aagttggacc gtctagtgaa atatcgtttg aatcgtataa aacgatcaat
     1621 ttccctagtt tcatatgacc tgccatcgaa cttgcttctt gagatacccc ttccatcaag
     1681 tctccgtcac cgcatattgc atacgtatag tgatccatca cattaaagtt ttctttgtta
     1741 tacgttgctg caaggtgcgc ttctgccatt gccataccga cagccattgc aatcccttgt
     1801 cctaatggcc ctgtagtggc ttctacacca tctgtatgat gtacttcagg atgtcctggt
     1861 gttttagaat cccattgacg gaattgtttc aaatcatcga ttgtcacttg atagccagct
     1921 aaatgaagca agctatacaa cattgctgac ccatgtcctg ccgaaagaac gaaacggtcg
     1981 cggtcagccc agttttttga tgtcgttgga tttactttca ggtgttttgt ccataacgca
     2041 tatgccatag gtgctgcgcc catcggcaat ccaggatgtc ctgagtttgc tttttggact
     2101 gcttcaatac ttaatgtacg aattgtgtta acgccaagtt ggtcaatttt gtcaaacaaa
     2161 ataacccctc ctattaattt aggttttttt tacctttatt tcttacactt tcattctata
     2221 agatgtcaca cgaaaaagca atctttttca gtatttttta ctaaaagttg tcatttcggt
     2281 tgtgtaagcc ttttttcttt tggatttctt ttaatttttc cggggtcacg tcattgccct
     2341 caggatcgac gactttcatt ccttcgatat gatgacgcat accggaacga aaagcttcca
     2401 aatactcttt gcgcaagttg atttgttctt gttcttcggc ttttgagaga ccattttcct
     2461 tctttttacg tgcaagttca ttgatccgct ctattttttc aggtgacagc atgctcagcc
     2521 ctccttttac tctccttcat attatataaa aactgaaaaa aaaacaacta gataaactaa
     2581 ataaaatacg aacattcgtt tgatttagcg ctttttatat ggtactattt atttatcaag
     2641 tgaaagaagg tgtaccttgt ggcccgacaa actgaatcaa gacaaatcga agtcttacga
     2701 tatatccatg aacaagtaac ccaaaaagga tacccgccga ctgtccgtga aatcggggaa
     2761 gctgttcagc tttcttctac ttctactgtt cacggtcatc ttgcacggct tgaaaaaaaa
     2821 gggtttatcc aaagagatcc gacgaaacct cgtgcaatcg agttgacaaa acaaggttta
     2881 gaaaagattg ggattcgtcc aacaactatt ccagtacttg gcgtcgtaac agctggagaa
     2941 cccattttag cagtagagga tgcttcagac ttctttccaa tccctcctaa tctttcttcc
     3001 gaagaaggca gtctctttat gctgacaatt cgtggagata gtatgatcaa tgctgggata
     3061 ttggatggtg acaacgtgat cgttcggaag caagaaactg ctcaaaatgg cgatattgtc
     3121 attgcaatga ctgccgagga cgaagcgact tgcaaacgat tctataaaga aaaaaacttt
     3181 ttccgtctgc agcctgaaaa cgacttgctc gaaccaatca tcttagatca agtatctata
     3241 ttaggacgag tagtaggact ttatcgtagt catatctatt aattgctact aattaaaaga
     3301 aaacttttta aaaagagttt gagacgttgg tctcaaactc ttttttcgcc cgggttcttc
     3361 ttctttcaaa tttttatcac ttccctcttt acaaaccgaa caaatattcg tatactaaat
     3421 atacgaacaa ttgttcgcat aaattaaaga ggtgagaatt catgaaatca atgagacgtc
     3481 ttggcttagt attaactgtt ttgtttttag gtattattat tggtaatttc ggcatacgtc
     3541 cagctttact tgtgtttgtt ccgttattta ctttgtggtt catgttgtgg gatgaaaaga
     3601 agtaccgtca atctgagcgg cgcagaattc atgaagatca tttctatcat gagccctact
     3661 acagatccag gcaatcataa taaggattga ctgctaatta ttcaaaagac aagaagttaa
     3721 acttttacgg gggtgtgaca aaaatcggtc acatcctttt tttcgaataa acggtgttct
     3781 aaagccagtt tttcggtatt aagtcaaatt gcggaaaaag tgatttttta aacttctact
     3841 ggtctttgct tgtttccatt tataaaaaaa tagcgaccct caaaagtcag atagagaatc
     3901 tgacttttga gggtcgcttt aaaatcgctt ctttaagaat aacatcaaga atagcttctt
     3961 ttttctgctt aatattccat taatgtaatg atgtcatatc ctttgatttt gtcgcgtcca
     4021 tggagatcca tcaattcgat caaaaatgcg cagcctacga ctacaccgcc taattgttcg
     4081 atcagttcga tcgtcgcttt gattgttcct ccagtagcta gcaaatcgtc acaaatcagc
     4141 acacgttgac ctggtttaat ggcatcctta tgcaatgtca atgtatctgt tccatattct
     4201 aatccataag tcacttcgat ggtttctcga ggtaacttcc cttttttgcg gactggggca
     4261 aaaccgactc ctaactcata agcaacagga catcctacga tgaatccacg ggcttctggc
     4321 ccaactacca tatcaattcg tttttctttt gcataattta cgatttgttt agtagcttcc
     4381 cgataagcgt caccatctgc catcagtggg gaaatatctc gaaacacaat tccttttgac
     4441 ggatagtcgg gaatactggc aatataatct tttaaatcca ctctttgttt cctcctaggt
     4501 tgttaaccat ttctttatgg taggaatatc gctcaaaagc aaaaattcct caactttgat
     4561 tttattgagc cgtcgctggt ataatctgct ctcagtcaaa ggatgacttt ctgggctagc
     4621 gactttttgt aaaacaccgt tctctattgt aacaaatttc aattcaaaaa acacctgtat
     4681 cataaaaatt aataattttt cagggatacg caaatattga gctattgctt ttattttatg
     4741 acgtatatca attcgttctt gagaatggat caatttaaac aattttgcgt actgttctct
     4801 tgtgcctacc ccattcaaat aggcctcatc aggtgaaatc cccatcagat aaacacgatt
     4861 gaatgaataa gaccgaaaaa cttctttcag atccgctaaa tcatctggac aatccataac
     4921 aactagagag tttggttttc ttttttcaat tattgccttt acagaatcta gtccttcgaa
     4981 aacaatcgca gcttcctgga taatctcagg cacgaatttc aacgtcgaag aatcaaatgc
     5041 taaataaagg ctaccttccg acgttcggct ctgttcacgg aaacgttttg cccgccaatc
     5101 aaatacttgc agaccaccca cagaaaaatc agataccatc agctgcggtt tcttacgccc
     5161 gttccattca ttgatcgaaa gctttcctac cacatctacc tgattattca gcagttcttc
     5221 ttcttgagta ccaaaaccaa aagcgaccgc atcaagctga ctcgatgcat cggaaaggac
     5281 aaatttcaga tgctgttggt ttgctccgat tcttttgata ttttctgctt ggacttgtcg
     5341 aaataaaaac tgaggcaaag gattatccgt accaaatggc gccaatagtt tcagctcatc
     5401 aattcgctct actgttactt catttggcag caatacttca tcaattctca actcaggccc
     5461 tctcatcaag tcaatttgat gatcgactat atattggttc atcttctcct gtagtatagt
     5521 gacattttca cttggcatcg ttaaaccgac tgctgcatga tgtcctccga agtaagtaaa
     5581 taaatctcgc atctggtcaa gcatttcaaa aagattcaag gcttcaatac tacgtccaga
     5641 tcctttagct gatccatctt cttttaaagt aaggacaagc gttggtttac ccgtttcatt
     5701 cattattttc ccagcaacaa tgcccaaaac gccttcatgc catcctcggt ttaccaatag
     5761 atggatatga ttctccttat tgaccatcgc taatgcttct tgtgttatct gctctacgat
     5821 tgcttttctt tcttcattga tctcattcaa tttttttgct tgaacggatg cttcctcttc
     5881 atcaaacgtc gcaagtaacg agacggcagg acgtggatcg cccatccgac cgattgcatt
     5941 tagtctggga gcaatcgaaa aaccgatcgt tgtttcgtct gcgtccctca tttttacgcc
     6001 gctttcttca aatagcgcct gaagtcctat ccgttctgaa tgatgaatgg catcgattcc
     6061 taatgaaaca aggattcgat tctcatcagt caatgaaact aaatcggcga tcgttcctat
     6121 cgctactaaa tccaaaaatt ctgcaggcgg ttcttccaat aatgcagaag ctactttgaa
     6181 tgctactccg actcctgcca aatctggaaa tggatagtgc cccgctggat gacgagggtg
     6241 aacaatcgca taagcgtctg gtaaattctc aggtagttcg tgatgatctg taatgatcac
     6301 gtctacacca gcttgctgag cgtatgctac cgcatcattt cctgctaccc cgttatcaac
     6361 agtgatgatc aactggattc cttcttcgat cttttcttgg tataccgatt ggtttggtcc
     6421 atacccatgc tcaaatcgat ttggcaggaa tacttctact tctgcaccaa gtaattccag
     6481 tgtttctttc attaccgttg cactggtgat cccatctgcg tcataatcac cgtaaacgag
     6541 gattttttct ccactgatta cagcttcttg gattcggctg attgctttat ccatatcgtg
     6601 tatcagatac ggatcatgta attcttgttc ctttggatgt aaaaatcggt tgatatcctt
     6661 ttcctcatgg taacctcttt gccacagtaa cttaccgaca aatggagata atttcagttc
     6721 acggatcatt tggagaaagg attcagaagg ctctgtctcg cttaacttcc aatcaaaatt
     6781 tgcttgtctc actttctcac tcctaactta gttattatag caaaggaaat cagcaaaaaa
     6841 aagcagaaag aaagaataaa aacagatcag atccgctaga cagatgttca gcaggacctg
     6901 atcttttgta cgaccattta tgaaatatcc ctattagtca aaataattga agctttgttt
     6961 gggcgattga gttttttgtt cttccggcgc tttcaattga ctgatttgtg cggttttcgc
     7021 ttgtaactcc gcctgataag cagcttccaa ctccgcacgt tcgtttctaa actcgcgttg
     7081 ctgttcttct tttgcttctt caattttctt ttgaagttct gtttgatatt ctgacatttc
     7141 ctgagtcagc tgtttgattt gctttttttg ctgccatagt gttgccgaag cagtcaaaaa
     7201 tacaatcagt gcaccaatca gcgcagaacc gatgatcact aagatcaatg gcgcagaaaa
     7261 ggaagtgaag ccaaaactta caggaacatt tttattgttc aatacagcaa aaagaacaat
     7321 aatcaaaact aaaacaaatc caagaatcac attgctttgc tttttcaatt ccttcaccta
     7381 ctttttgtta aaaattccgc tggctaaata atcaccaatc gttggaaaca gcgtataaaa
     7441 ttttgatgca acttctaaaa taaacggttg attgatttcc cgttttggat gtctcatatt
     7501 gcggacgatc atttttgcca acttggcagg ttctaaaacg atttgtccga ctttttccaa
     7561 atagcttccg cttggatcag ccttatcgaa gaaatttgtc tcgattggac ctggattcac
     7621 tgtcgtaaca gctacgccaa gtggtttcaa ttctaatcgc aaagcgttgg agaagccaag
     7681 gactgcaaat ttcgtggcag aataaaccgt tgattttgca gttgccattt ttccagccat
     7741 agaggcgata ttaatgatat gaccttgtct tctttctgcc atatcgatcg caaatttttg
     7801 tgtcaaaacc atcattccta agatgttgac ttcaaacata tcgtatgctt ttccaaggtc
     7861 gaatgtaagg aagtcttcga aaatcccaaa acccgcattg tttaccagaa tatcgacgcg
     7921 cccgacttct tccatcacct tttcatataa ttcgtccacg ctttcaggat tgctgacgtc
     7981 taccttgaaa gcataagcct ctttgccgct caagcgtctg cactcgtctc tgacaccttc
     8041 tacaaatgcc attcttcgtg cgcaacttat aacgattgct ccttgctttg ctgcttcata
     8101 acagatttgt gcgcccagac cgcctgaact acctgttact aaaacaactt tatcttctaa
     8161 attcatgcct cttcctcctc gcgaaatgga atctcaatgc tatcaaaatc tttcataatc
     8221 gtcgtgtttt caaacacttc ttgtgcttct ttttcaagct ctaaagctgc ttttcctaaa
     8281 tatctcgcac tgatatgagt aagtagcagc cgttttgcct gcgcttcttt tgcaacttca
     8341 gcagcttgat gagtcgtgga atggaaatag ttgtgcgcca ttcttgcttc atctttatta
     8401 aatgtgcttt catgtaccag aatatcgcta ttttccgcaa gcacaacgga attatgtgtt
     8461 tttctcgtat cgcctaaaat agtcacgatt cgtccttttt tatctggacc tacgaaatct
     8521 tttccattga tcgtccgccc atcttctagt tggatcgttt caccttgctt cagtttgccg
     8581 tacagtggtc cagctggaat acctaattct tttagacgat ccacctgcaa ttctccttta
     8641 tgatcatgtt caaccacacg ataaccaaaa ctgtcgatcc catgatttag tttttttgta
     8701 taaacagaaa attgctgatc agtaaaaatc ggggctgttt catttagctc aatgaatttc
     8761 agcggataac ttaaacgcgt ttgcgaaata cctaaagaga cttttatgta ttcctctatc
     8821 ccttttggcc cgtaaatctc taatggcgta tccccacctt gaaatgaccg gctgctgatg
     8881 agcccgggaa gtccaaaaat atgatcgccg tgtaaatgtg taatgaaaat tttaccgatt
     8941 tttctcggac gaatagtcgt tcgcaaaatc tgcatttgcg tgccttcgcc acagtcgaac
     9001 aaccaaactt cattgcgctc gtctaaaagt ttcaatgcta tacttgtcac atttctatgt
     9061 tttgcaggaa cacctgcacc tgttcctaaa aattgtaatt ccataatcta cctgactttc
     9121 tttaagttcc tctttaattt tagggtaaaa agaagggata atcaaccgta agtcgagaat
     9181 gggttcaaat taaaaataac gttctaaagc gatagcgttt tctttgaaaa ttactataaa
     9241 aacagcagcg aacccgtttg agatcctctg ctgtttttta ttaatttgaa gatccagaac
     9301 tttcattgtc gttggaagtt tgcggatgtt tgtccttcca agtcttttgt gcagcttctt
     9361 tcgcatgatt ttcagcttct ttcgcatcat gcacatcttt ttcgacatct tcataatcca
     9421 agcgagtaat ttctccgcct aattccatca ttaccaattg attcagtggg cgattgtcct
     9481 cttcatcagc aatcaagatc agtcctgtag ctccttcacc gattttattt cctacaaagt
     9541 cgaacacggt ctgggcatct tttatttctt tggcatcttg tgtcgcaccg atcattcctc
     9601 cggcaaacca tcctaataaa atccctagcg gaccacctaa tacaccaacc aacattccga
     9661 ttaatccacc cgtagaagat ttgttattac cggtaaagtc gataaaatct tctattttga
     9721 attgatgtgt cccattagga tcatggctga caactgccat ctgttctcct ttaatcgaac
     9781 gaacagcatg taactttttg atttctgaaa atgcctgata tgcctggctt tctacttgaa
     9841 aatttaaaat gattactcgt ttgctcatta aaaacgcccc tttcatacct tcttgttatt
     9901 tattttacct ttaattgaaa aataagaaaa gaaaagcact ctttttttcc aataaaatag
     9961 ggctgtgaca aaagtcgtat cacagctcct ttttccgaat aaacggcgtt cttgaagctg
    10021 atcacttctg tcacaacctc ccttaaatct gaatctatat tttttggtat ttgtttttat
    10081 ttgcttgcct attcgacaaa ttcaaattca aactcaccga tacgtacaag gtcgccatct
    10141 ttcgcaccgc gtgcccgaag agcttcatcc acacccatac cacgtaattg acgagcaaaa
    10201 cgcatcactg tttcatcatg atcgaaattc gtcatttgga ataatttttc gatcttctca
    10261 ccagataaga tccacgttgc atctgaatca cgatcgattt ggaactcagg accttctgga
    10321 ttgaatccat agtgtacagt ttcttcttcc agttcttctt cgtacaatgg gaattctggc
    10381 gttacttcta acaaatctgc tgtagcattc aataacgcgt ccaatccttg tcgagtcact
    10441 ccagaaattg gaaatactgg gatgtcatca gcaaattcat cttctttttc cttgttcagc
    10501 tgttctttga atttcactag attttccggt gcatccggca tatccatttt gtttgccacg
    10561 atgatttgcg gacgctctag caagcgtaag ttataagtag ataattcttt gttgatggca
    10621 agatagtctt cataaggatc tcgtccttcc atcccactca tatcgatcac atgtaaaatt
    10681 actcgtgttc tttcgatatg acgaaggaat tgtgtaccca gcccaacacc ttgcgaagct
    10741 ccttcaatca agcctggcaa gtctgctgcg gcaaaacttc tgccatcact tgtagtaacc
    10801 attcctagat taggtacgag cgtcgtgaaa tgataagcgc cgatttttgg acgagcagat
    10861 gaaataacgg atagtaaagt cgatttcccg acagatggaa aacctacaag tccaacgtct
    10921 gccaatactt tcaattctag ttcgattttt cgctcttgtc ctggttcacc gttttcagca
    10981 atttccggtg caggattccg aggagaggca aaacggatat tccctcgtcc accgcgtcca
    11041 ccttttgcca caactagtgt ttgaccattt tcaattaaat ctcctaaaag agcaccagtc
    11101 tccgcatctc ggacagtggt tccttgtggt actttaacat aggtatcttc tgaaccacga
    11161 ccgtgcatcc ctttactcat cccattttca cctggctgcg ctttgaaatg gcgattgaac
    11221 cgaaaatcca tcaatgtacg taacccttca tcgacgatca agatgacatc gccgccacga
    11281 ccaccgtctc cgccagccgg tccgccgtca ggaacgtatt tttcgcgacg aaatgcaacc
    11341 attccgtctc cgcccttgcc agctttcaca tcgatcgtta cttgatctaa aaacatggac
    11401 ataattaagt cctcctatta ttcatttatt tatttgactg cctgaatttc cacaataaac
    11461 aaaagtctta cttattttat cggtgaaatc tgattttgtc tatcatttca gcaaaaagat
    11521 tgtttacctt cttctttttt tatcatttgg taaggtttcc aacctttttt ctgctaccaa
    11581 gtataatttt ttgacaaaat attctttgcg tagcagaata acagtgtatt aattgtatta
    11641 attgaggatg ccgtttcaca gcacccctaa taaaggagga acttttgata tgacagtaaa
    11701 agtaggtatt aacggatttg ggcgtattgg ccgtctggct ttccgccgca tcaaagaagt
    11761 ctcagatgat attgaagtag tagcaatcaa cgacttaaca agtccaacta tgttagcaca
    11821 attattgcaa tttgactcta ctcatggtac ttatcctggc acagttactg caacagaaga
    11881 ctcaatcgta gtggatggcg aagcaactcg tgtttatgca gaacccgacg caagcaaaat
    11941 cccttgggca aaagaaaacg gtgtagatat cgtactagaa tgtactggtt tttatacatc
    12001 tgaagaaaaa gcaaaagcgc atttagatgc tggtgtcaaa cgagtagtta tttctgcccc
    12061 agctggtgct atgaaaacca tcgtctataa cgtcaatgat gatacattag atgaaaacga
    12121 caaaatcatc tcagcaggtt catgtacaac aaactgttta gcacctatgg cttatttctt
    12181 aaataatgaa tttgggatcg aagttggtac aatgacaaca gttcatgcct acacttccac
    12241 acaaatgctc ttagatggac ctgtaaaagg cggtaatttg cgtgctgctc gttcagctgc
    12301 tgacaatact atcccacatt ctactggtgc tgcgaaagca atcggcttag ttatccctga
    12361 gctacaagga aaattacaag gacacgcaca acgtgttcca gtcgttgatg gttcattaac
    12421 tgaattggtt tcagtattga aaacaaaagt aactgctgat caagtaaacg aagcaatcaa
    12481 aaaacacaca gttgacaatc cttcattcgg gtatgatgac cgtcaaatcg tttctagcga
    12541 tgtcattgga acaactcaag gttcgatctt tgacccaacg caaacagaag taacaactgc
    12601 tggtgatttc caacttgtta aaactgttgc atggtatgac aatgagtatg gatttacttg
    12661 ccaaatgatt cgcttactag aaaaattcgc taacttgtaa tttgatagat
//
LOCUS       DACBZK010000074        12583 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.077, whole genome shotgun sequence.
ACCESSION   DACBZK010000074 DACBZK010000000
VERSION     DACBZK010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.077"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            46..897
                     /locus_tag="IVD66_002240"
     CDS             46..897
                     /locus_tag="IVD66_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6146432.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            951..2702
                     /locus_tag="IVD66_002241"
     CDS             951..2702
                     /locus_tag="IVD66_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6146433.1"
                     /translation="MAKPSTNKLEGIEMGKYQELARKIVENVGGKENINGLTHCITRL
                     RFKLKNEEKANDEILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAV
                     STEKMRPFDMLIDGISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNI
                     GDSVFQFMPVIIGLTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSG
                     TIFEAPIYQTVFGIPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFF
                     TVLITMPLGFLLVGPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWA
                     IVPMGLMQFSVNGWQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVG
                     ITEPAIYGFTLPRKKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGD
                     LTDVINVLIGIAIAMVVSFTLTFFFWKDEAGETDDIQKKSGKEIVKTPIQGQIAPLNA
                     AKDAAFAQGTLGRGILIYPEKGEVRAPFDGTVMTLFPTKQAIGMVSETGLELLIHVGL
                     DTVQLEGKYFESLVQQG"
     gene            2706..2876
                     /locus_tag="IVD66_002242"
     CDS             2706..2876
                     /locus_tag="IVD66_002242"
                     /inference="COORDINATES: protein motif:HMM:NF012578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146434.1"
                     /translation="MKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGET
                     VGPDDALITALT"
     gene            complement(2916..3818)
                     /locus_tag="IVD66_002243"
     CDS             complement(2916..3818)
                     /locus_tag="IVD66_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP6146435.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            4049..5452
                     /locus_tag="IVD66_002244"
     CDS             4049..5452
                     /locus_tag="IVD66_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP6146436.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEENGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            5452..6885
                     /gene="ascB"
                     /locus_tag="IVD66_002245"
     CDS             5452..6885
                     /gene="ascB"
                     /locus_tag="IVD66_002245"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP6146437.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDAFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEKGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYASRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            7030..7956
                     /gene="trxB"
                     /locus_tag="IVD66_002246"
     CDS             7030..7956
                     /gene="trxB"
                     /locus_tag="IVD66_002246"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HAP6146438.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            8170..9897
                     /locus_tag="IVD66_002247"
     CDS             8170..9897
                     /locus_tag="IVD66_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAP6146439.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            9969..10262
                     /locus_tag="IVD66_002248"
     CDS             9969..10262
                     /locus_tag="IVD66_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAP6146440.1"
                     /translation="MPDTQKSKVEKVSQLFKMLSDPTRLKILLYLKDGEQNVTAITQA
                     VEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHVLDILNQTLKHVEHQ"
     gene            complement(10354..11214)
                     /locus_tag="IVD66_002249"
     CDS             complement(10354..11214)
                     /locus_tag="IVD66_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HAP6146441.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            11306..11734
                     /locus_tag="IVD66_002250"
     CDS             11306..11734
                     /locus_tag="IVD66_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAP6146442.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            11896..12072
                     /locus_tag="IVD66_002251"
     CDS             11896..12072
                     /locus_tag="IVD66_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HAP6146443.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            12099..12545
                     /locus_tag="IVD66_002252"
     CDS             12099..12545
                     /locus_tag="IVD66_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HAP6146444.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT         4132 a         2147 c         2774 g         3530 t
ORIGIN      
        1 ttttgttttg gatacagccc tatacatcat ggaaaggagc aaaacatgct gattgagaaa
       61 gtactgaata acaacgtcgt aataaccagg gatgaaagaa atcaggaaat gatcgtgatg
      121 ggaaaaggtt tggcattcaa aaagaaagtg ggtgacccga tttttgactc atgcatcgac
      181 aaaaaatttc agttgacaaa tgacgggctt tcacaacagt tccaagaatt ggcacaagcg
      241 attcctcttg agtacttaga aatttcttgt gaaatcattg aatatacaaa agaggctcta
      301 caagtccagt tgaatgattc tgtgtatatt gcattgacgg atcatttgta tacggctatc
      361 gaacgtcaca aaatgggaat atttgtacca aatgtattgc tgtatgatat caaacaacta
      421 tttcctaaag agtatgccat cgggaaaaaa acagtgaaga aaatctcgga taaataccac
      481 atcaagttat cagaagatga agccggattt atcgcattgc atttagtcaa tgcacaaggc
      541 attcaaagcc agcaagacaa tacctacctg tttactataa caatacagga tattctaaat
      601 atcgtccgct attactataa gattacattt gatgaagatt cagtccattt ttttcgattc
      661 gtcacacact tacgtttttt tctgacacgc gtcctagatg gagaaaaatc agaagtggga
      721 gaagtttctg aggaattgtt tcaggttatt caaaaaaaat ataaggatac gtttggttgc
      781 gttgagaaaa tagcagactt tttagccgag acgttcaact accagatgtc cacggacgaa
      841 aaaatgtatt taacgatcca tactgcgcgt ttagtgcatg agaatcgttg taaataaaaa
      901 aaggaggata aattaacaag aacgtatgaa ataagggtag tgacattcag ttggctaaac
      961 cttccactaa taaattggag ggaatagaaa tgggaaaata ccaagaatta gcgagaaaaa
     1021 tcgtagaaaa tgtcggcggg aaggaaaata tcaatggttt gacacattgt atcacaaggc
     1081 ttcgtttcaa attaaaaaac gaagaaaaag caaatgatga gatcttgaaa aatatggacg
     1141 gtattgtaac ggtaatgcga gcgggagggc agtatcaagt tgtcattggg aatcatgtgc
     1201 cagtcgtgtt tgaagaggtt ataaaagcag gaaaccttac ttttgatgag gctgtttcaa
     1261 cagaaaaaat gagaccgttt gatatgctta ttgatggaat atcgggctgt ttccagccat
     1321 tccttgctat cctagctgct ggcgggatga ttcgtggact gacagcattc cttgtcttct
     1381 taggcgcgtt tgaccgcggt tctggcacat ttgttatgtt tgataatatc ggtgattctg
     1441 tattccaatt tatgcctgtt attatcggtt taacagctgc ccgtaaattt aaagtaaatg
     1501 aattcgtagg gatgttgctt ggcgcagcat taatgaatcc tagcttgtcg ctggaagctt
     1561 tgagtggtgc agcagaagca ccactaacga ccatattttc tggcactatt tttgaagcac
     1621 ctatttatca aacagtattc ggcattccct ggattgcgcg taactacgct tcttctgtca
     1681 ttcccattat ctttattgtg ttgttagcta gccaaattca gaaaccaatt aaaaagttag
     1741 tacctgagat gatcgcgaat ttcttcgttc cattcttcac cgttcttatt acaatgcctt
     1801 taggtttttt actcgttgga ccagtattca cattcgcaac tgatatttta atggctggat
     1861 ttgaaacact tttagcactt tcgccagtta tttatggagc aatcgtaggc ttcttctggc
     1921 aaattctggt gatgtttggt ctccattggg caatcgtacc aatgggattg atgcaatttt
     1981 ctgtgaatgg ttggcaaaat attatgacac ctgttgcagt agtgtctttt ggacaaactg
     2041 cagcacttac cgcactctac tttaagctta gaaatccaaa agacaaagca attgcaatac
     2101 cagccattgt ttctggtatt gtggggatta cagagccagc tatttatggg tttacattac
     2161 cacgtaaaaa aatatttatt tttacctgtg tcggtggtgc gttagggggc gcgtatagtg
     2221 ggttaatgaa tttaacttct tggaatcaag gtggactagg catctttaca attcccaact
     2281 atattagacc agatggtgat ttaacagatg tgattaatgt attgattggg atcgccattg
     2341 cgatggtggt atcctttacg ctgacttttt tcttttggaa ggatgaagca ggtgaaacag
     2401 atgatataca gaaaaaatca ggtaaagaaa ttgtaaaaac accgatacaa ggacaaatcg
     2461 ctccactaaa tgcagcaaag gatgcagctt ttgcacaagg aacactaggt cgaggaatct
     2521 tgatctaccc tgaaaaagga gaagtacgtg ccccttttga cggaacagtc atgaccctgt
     2581 tcccgacgaa acaggcaatt ggaatggttt ctgaaacagg gctggaattg ctgattcatg
     2641 tcggattgga tactgtgcag ttggaaggga aatattttga aagcttagtg cagcaaggat
     2701 aaagagtgaa acaaggcgat ctgttgctac gcttcgacaa aaagaaaatc gaaaaggaag
     2761 gatacagttt agaaacacct gtgatcgtca ccaattacac ggattatttg gatattttgg
     2821 aaaaccaagg ggagacggtc gggccagacg atgcacttat caccgcactg acctgaacgg
     2881 ttaggtgaag aatggactag gcttaactat tctttttatt ccacttcttt attttcaaaa
     2941 ttgaaaggct ctttcatgat ggctgagctg atagggcgtt tatcgaattt ttgaccgaca
     3001 gaaattagat ggactaaatt ctgttgataa ttttctgcaa aaacacaact atataacacg
     3061 tctagaagat aacaaattga tgtattgatc gtaaaattac caatttttga atacagtcgc
     3121 tcgcgtgtcg taagtcgcaa agcggctgta ctcattgcag atagcgttga atcaccgata
     3181 ctggtcaaag ctaaaattgg aacatgattt tgtttcaata tttctgcggt acgaaggatc
     3241 acattgtttt cacccgtata agaaatcaga atcccgcaca tatcactcgt gcaattgtac
     3301 gcttcataga atgattcacc aaaagtggtg acaatcgtga catccatttt gatgcgcttc
     3361 attttcagca tgaaatcttg agaaatcaaa gtattcgagt tactggcgaa aatcacgatt
     3421 ttttttgctt gaagcattag ttgtttggct ttttgcagtt ggtcatgatg aatgagagaa
     3481 agtgtatcat gaatcgtcat ctgttctaaa gaagccattt tatttgcgat cgtcataata
     3541 ccgtctgtgg tggaaaaagg aagattcgca tctacgtctt gaaaattccc ttcaagatag
     3601 gctgtttcag ctaaaaaagc attacgaaaa ctgacccagc catcaaaacc catttttttt
     3661 gctacacgga tgagtgtaga ggggtggaca taacatcgct cagcaatcgc ttggatggtc
     3721 atttcgccaa gtgctggaga atcgcttaag agaaactgga tcacttcatt ttctgaagga
     3781 gaaaaggaga tttctttgat tttttcacgt aataacatgt agataccttc ttcttatttt
     3841 tttacgtaaa ttataacttt tttgaaaatg atttgtaaac ggatttatac tatataactt
     3901 aaaatagaca ttttttgaca agatatttac aaaaatccac tagaaaacag taaattttgt
     3961 aaatgttact ggaaagaaac agatttctat tgtttgtttt gtttacaaaa aagataatga
     4021 aagtgtaaaa aagtaaagga gtgagaacat ggcaaaagga atcaaaatcg ctacgattgg
     4081 tggaggcagc agttacaccc ccgagttgat ggaaggattt atcaaaagat atgaggaatt
     4141 accgatacga gaaatctggc tcgtagatgt agaagaagga aaagaaaagc ttgagatcgt
     4201 tagtcagatg tctcagcgta tgtgggatgc ttctccgtat gaagtcaaga tctatgcaac
     4261 tctggatcgg gaagaagcat tgaaagatgc ggattttgtt acgactcagt ttcgtgtcgg
     4321 tcaattagat gcacgaatca aagacgagcg gatccctagt tattatggga tgattgggca
     4381 agaaacaaat ggtgctggcg ggatattcaa agcttttcgt accgttccag tcgttttggc
     4441 aatcgttgag gacatgaagc gtttatgtcc aaatgcttgg ctgatcaatt tcgcgaaccc
     4501 aagtgggatg gtgacagaag cagttatcag atatggcaaa tgggataaag tgattggatt
     4561 atgcaatgtg ccagtgatgg cgatgatgac agaaccagca atgcttggca agaaaaaaga
     4621 agagctgatc tacaagtttg ccggtctaaa tcatttccat tggcacaaag tagcagataa
     4681 taaaggaaat gaccgcacgg cagaattgat tgatcgttta tacgatgaag agaatggatt
     4741 accgaaaaat atctttgata tcccgttttt caaagaacaa ttaaaacaaa tgaacatgat
     4801 cccttgtggc taccaccgct attactatcg tgaagaagaa atgctggaac atgctttaga
     4861 agaatatcaa acgattggta caagagcgca gcaagtgaaa gaaacagaag cagagctatt
     4921 tgaattatac aaagatccag aattagacca taaacctgaa caattgcaaa aacgaggtgg
     4981 cgcttattat tcagacgctg cctgtgaaac gattgcttca atctatggaa ataaagaaac
     5041 acagatcgtg gtatctacaa agaatgatgg agctgttcct gacctgccgg cagattgtgt
     5101 agtagaagtc actgcctatg ttggcgcaca aggagcgaga aatgtagcgt ttggttctct
     5161 tcctgctgct gaaagaggct ggttgcaagt aatgaagaat atggaattgc tgacgatcga
     5221 agcagctgtg actggtgatt atgggacagc tttacaggcg tttacgatca atccacttat
     5281 acgatcagga aagacagcaa aacggatcat ggatgagttg tttattgcac accagcagta
     5341 tttaccgcaa ttcaaggaga caatcagccg attaaaagaa gaaggaatcg aagttcaaga
     5401 tgaactggca agagaattat caggtaatac acatataatg gaggaagtat aatgggattc
     5461 agaaaagatt ttttatgggg cggtgctaca gcagccaatc aatgtgaggg cggttatgat
     5521 gaaggtggac gcggactagc aaacgtagat gttgtgccaa tcggaaaaga ccgttttcct
     5581 gttatcaccg gaaagaaaaa aatgtttgaa tttgatgagg atcattttta tccagcaaaa
     5641 attgcaatcg atatgtatca tcgttataaa gaagatattg ctttgtttgc agaaatgggg
     5701 ttcaagactt atcgaatgtc catcgcctgg agtcgtattt ttccaatggg ggatgagaaa
     5761 gagccgaatg aagctggctt gaaattttat gaggatgcct ttaaagaatg ccaaaagcac
     5821 ggaattgagc cacttgtgac gattacgcat tttgattgtc caatgcattt gatcaaagaa
     5881 tatggtgcgt ggcgttccag agaactcgtt ggtttttatg aaaatctgtg tcgagtcatc
     5941 ttcaatcgct ataaaggact tgtcaaatat tggctgacat tcaatgagat caatatgatc
     6001 cttcatgcac cattcatggg cgcagggctg tattttgaaa aaggagaaaa tgaagaacaa
     6061 atcaaatatc aagcggcaca tcatgagttg gttgcaagtg ccatcgcaac gaagattgct
     6121 catgaagtag atccggagaa caaagtaggc tgtatgctgg cagcaggagc atattatcca
     6181 tacacttgca atcctgaaga tgtttgggct tctagaaaat cagatcgaga aaattatttc
     6241 ttcattgatg tccagtcacg aggagaatat cccgcttatg cattgaaaga aatggagcga
     6301 aatggcattc agatcgaaat ggaaccaggg gatgccgcat tgctgaaaga acatactgtt
     6361 gattttatct ctttttctta ttatgcttcc cgagtttcga ctaccgacaa cgaactcttg
     6421 gaacagactg caggaaatat ctttgcttct gtcaaaaatc catatctgca agcaagtgaa
     6481 tgggggtggc aaattgatcc attaggcttg agaataacga tgaatgatat ttatgatcgt
     6541 tatcaaaaac cattgtttat tgtagaaaac ggcttaggtg cagtcgatac gccagatgaa
     6601 aatggttatg tggaagatga ttaccgaatc gattacctgg cagcgcatat ccaggcgatg
     6661 aaggatgcag tagaactaga cggagtcgat ctattaggct atacgacttg gggatgtatt
     6721 gatttagtat cagctggtac cggtgagatg aagaaaaggt acggattcat ttatgtcgat
     6781 cgtgataacc aaggaaatgg cacattagcc cgttcaaaga aaaaatcatt caactggtat
     6841 aaaaaagtaa ttgattcaaa tggagaaaat ctttcgaacg attgatcaat gatttataaa
     6901 agtctattgt ttttcagcgg atttttcgag tataataaag ctattcgaga aacgcaagca
     6961 gaacaataga ctttttttcg cattggctgt aaagtatgct tacttgatta agtaaaggag
     7021 aatctacata tgtatgatgt aatcgttatt ggcgcaggtc ctgctgggat gactgctgct
     7081 ttatatgctt cacgttcaaa cttatccgta ttgatgatcg aacaaggtgc ccctggcggc
     7141 caaatgaaca atacggcaga aatcgaaaat tatcctggat tcgattcgat catgggcccc
     7201 gatctagctt ataagatgta tgaaagtgtc tcaagatttg ggacagaaaa tgcttatgga
     7261 atcgttcaag atatcaagga tcacggcagc cataaagaag tcatctgtga agataaaagt
     7321 tacgaaggaa aaacagtcat tatcgcaaca ggatgtatcc accgtaaatt aggcgtacct
     7381 ggcgaggaag aatttgctgg acgaggcgtt tcttactgtg cagtctgtga tggtgcgttt
     7441 ttccgtaaca aacgtctagt agtcatcggg ggtggggact cagcagtaga agaagccatc
     7501 tatttgacac aatttgcttc tgaagtagtg atcgtccacc gtagagatga attacgtgca
     7561 caaaagatca tccaagaccg tgcatttgca aatgaaaaaa tttcctttat gtgggataca
     7621 gtcgttgacg aaatcgttgg aaacgaaatg gtagtgacag gtgtgaaagc acgtaatgtc
     7681 aaaaccggca atgaatttga tttagcagca gacggagtat tcatctatgt tggactggat
     7741 ccattaactg caccttttag agaagcaggt ttgacgaacg aagctggctg gattccaaca
     7801 gacaacgaaa tgaaaacgaa tatgccaggc gtttttgcca tcggagatgt tcgtgaaaaa
     7861 gatttgcgac aaatcactac agctgttggt gacggcggta ttgctggaca acaagtgtat
     7921 aaatacttgg agtctttaga agaaacaaca gcataagttt aaaaagagta gaagaacggg
     7981 ttcaattgtt cttttactct tttttttcgc gtgaaattta ctgaatctga tttatgcgaa
     8041 cacgtccaac accttttgat aaaagaatcc tttcttgatt taagcgtttt ttggtcctca
     8101 tactttcata tctaataagt gaatgctata cttattaaga accatatttc agaaagaggt
     8161 gttattttca tgtcttggga acaagtgtat gaacaatggg tacatgaaga aaatttagaa
     8221 gaaaacttaa aaaaacaatt aaatgatctg ggtgaagatc ctgaaaaact tgaagatgct
     8281 ttttatgcac cgttggaatt cggtactgca ggtatgcggg gaatcttagg acctgggatc
     8341 aatcgaatga acatctatac ggtaagacaa gcaacagaag gactagcacg tttcatggat
     8401 acacaaggtg aagaaacaaa acgccgaggt gtcgctatcg cttatgactc acgccatcag
     8461 tcaccagaat ttgcaatgga agcagccaaa acactagcac atcacaatat cccgtcttat
     8521 gtattcgaaa gtctgcgtcc aacaccagag ctttcttttg cagttcgtca tttgaagacg
     8581 tttgcgggaa tcatggtaac cgcatctcac aacccagcgg cttacaatgg atataaagtc
     8641 tacggagaag atggcggaca aatgcctcct gcagacgcag atgcattgac gaaatatgtc
     8701 cgtgaagtca gcaatccgct aaaagtcgaa gtattatctg acgaagaagc taaacatagc
     8761 gggttgatca cgatcatcgg agaagaagtg gacgctgctt atctagaaga aatcaaagca
     8821 gtgacgattg atcgtgaatt ggttgaaaca atggggaaag atttgaaact tgtgtacacg
     8881 ccacttcatg gaacagggaa aatgttgggc gaacgtgcgt tgaaacaagc tggattcgaa
     8941 caattcgtac tagttcccga acaagctgtg gcagatccag atttcactac ggtcaaatcg
     9001 ccaaatccag aagaacattc agcttttgaa tatgctatac gacttggaga aaaagaagga
     9061 gctgacttgc tgattgcaac agatcctgat gcagaccgtt taggcgcagc ggttcgtttg
     9121 ccagatggtt cttatgaagt attgactggg aaccaaatcg gagcattgtt tgctcaatat
     9181 attttggaag cacatcaatc aagaggcact ttaccagaaa acgcagcggt attgaaatca
     9241 atcgtttcca gcgaattgcc tacagcaatt gcggaacact acggtgctac catgttcaat
     9301 gtgttgacag ggtttaaatt cattgctgaa aaaatccaac aatttgaaga agaccattca
     9361 catactttta tgtttggatt cgaagaaagt tatggttatt tagttaaacc ttttgttcgc
     9421 gataaagacg cgatccaagc attgctttta ttagcagaag tagcagctta ctataaaaaa
     9481 caaggcaaaa cgttgtatga cggcttgcaa acgatttttg aaacctatgg ctatttcgca
     9541 gaaaaaacga tttctgtgac aatgagcgga caagaaggtt ctgcgaaaat ctctgctttg
     9601 atggaaaaat tccgtaaaga agcaccgaca gaatttgccg gagcaaaagt tattcaaaca
     9661 gaagacttta aagaattgac gagaacagac cgtgaaggaa acgtagaaaa actaacaaca
     9721 ccgccatccg acgtattgaa gtatacattg gaagaaaatg gctggatcgc tatccgccct
     9781 tcaggaactg agccgaaaat caagttttat attggtgtaa aaggaagctc tacagaagac
     9841 gcagccgaaa aagtagcctc ttatgaagcg attatcaaaa agatgacaga agaataaaaa
     9901 acttgagact gatggaaaaa gtggtaaact ttagaagtca gtcttttttc aagttggagg
     9961 tgaatggatt gccagacacg caaaaatcaa aagtagagaa agtcagtcaa ttattcaaaa
    10021 tgttgagtga tcccactcgt cttaaaattc tgctatatct gaaagacggg gaacaaaatg
    10081 tgacagcaat cacccaagca gtggaaatgg agcagtctgc tgtatcgcat caactacgtt
    10141 tattaagaga aaatcatgtc gtcaagtctc atcgcgaggg aaaagcgatt ttgtatagtc
    10201 ttgatgattc tcatgtactg gatattttga accagacact caaacatgtg gaacatcaat
    10261 aacgataggt gaaaatagat aaacactgga gtgtgacaac gaagaaattt cgttgtcaca
    10321 ctccagtgtt ttttaagaaa aagacaaaaa tgattaatcg cttttttctg ttgtttcagt
    10381 tccataataa ctatgatctt ctaggtctaa agcattcaaa ataagcgaag ccgtttcttc
    10441 aatagataaa gatgccacat tgatcactac acatcctagt ttttcataaa gatcattcgc
    10501 aaaatcgagt tcagctctaa ttttttcgat atcggaataa gcagtatcag ggtttaatcc
    10561 gtaagagcgc atccgttctt tacggatatt atttaaaata tctgggttat tcgttagtcc
    10621 cacgattttt ttaggatcga tttcccacag ctgtttggga atatgtgctt ggggaatcaa
    10681 aggtaaatta gcaactttta aatttttatt tgctaaaaac aagctcaaag gcgttttgga
    10741 agttcgggat acgcctagca aaacgacatc tgcttctaaa aaaccacgag gatctttccc
    10801 atcatcgtat tttacagcaa attccattgc tttgatccgt ttgaaatagt tctcattcaa
    10861 taaatggagg gcaccaggtt gccgaattgg cttgatacca gttaaacgtt caatttctga
    10921 tatcggtggc gtcatcacat cgaaactaaa taattgatgt tcttcacaaa aagaacgtgt
    10981 tatctcgatc agttcttgat tgattaatgt atgcaggaca agtgcttttt cttctaatgc
    11041 atcttgcaat gcctgcctta atgttttttc atctgtcacg aacgttctgc ggaataggtt
    11101 gaactcaacg gtaggatact gagccatagt agcttgcgct agttttgtcg cagtttctcc
    11161 agcagagtcg gagatgacaa aaaaagtaac gatttctgta gaatcggaag acatggataa
    11221 aacctcactt gcattttttt tatgtttatt ataccatact ctagaatgcg tacttcgtaa
    11281 tcattttgat ttggaggaat aagtcatgaa aaaacagaca ttgatcgaac aatcattaga
    11341 aacattgaaa aataacggtt ttaaatatac taaaaaaaga gaagcattgt taacttattt
    11401 agtgaagcgt aaccgctacg tatctgctaa agaagttttt gactatatga atcaggaatt
    11461 caaaggggta agttatgata cgatttaccg gaatctccat gattttgcag agatcgattt
    11521 actggaagaa accgatttaa atggtgaaat gaagtttcgt tttcattgct gtcaggggga
    11581 aatcggccat caccatcatt ttatctgtac agtgtgcgga acaacgaaag aaatccatat
    11641 gtgtccaatg aattatttcg aagaacagct aggtggatgc acgatcgaag ggcatagatt
    11701 cgagattttc ggaagatgtg aaaattgtca ataaggattt aaataaaata acatttgata
    11761 atttaaaaaa aaagcaagat ttccttgacg gtcaaaacag cattagatat aatatttaca
    11821 ggacagtctt gttttttgag atatatttca ataacaatta cggttacttt ttaagctcgg
    11881 agggagggaa ttaacatgtc aaaaacagtc gttcgcaaaa acgaatcact tgacgatgct
    11941 cttcgtcgct tcaaacgttc cgtgtcaaaa gcgggtactt tacaagaatc tcgtaaacgt
    12001 gaattctacg aaaaaccaag tgtaagacgc aagaaaaaat ctgaagcagc tagaaaacgc
    12061 aaaaaattct agttctgtga tgaattggag ttggtagtgt gtcactacta agtagattaa
    12121 acgatgacat gaaagcagcg atgaaagcga aagataagga atctttacaa gtcatccgaa
    12181 tgatcaagtc atctatacaa aacgagcaga ttaaagaagg tcacgacttg acagaagaag
    12241 aagaactaac ggtgttgtct cgcgaaatga aacagcgacg tgattctttg catgagtttg
    12301 aagaagcagg acgtgacgat ttagctgaaa aagtaaaaag tgaaattgta atagtcgaaa
    12361 aatatatgcc ggaacaactt tccgacgaag aaattcgaca acttgttcaa gaagcaatca
    12421 ctcaaactgg tgcttcatca atgaaagaat ttggcaaagt tatgggtgca attatgccta
    12481 aagtcaaagg aaaagcagat ggaaaccaag tgaatgcgat tgtgaaagaa ctattacaat
    12541 cttaatttta tcatttaaac tgcggacagt gattgtccgc agt
//
LOCUS       DACBZK010000075        12526 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.078, whole genome shotgun sequence.
ACCESSION   DACBZK010000075 DACBZK010000000
VERSION     DACBZK010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.078"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(144..539)
                     /locus_tag="IVD66_002253"
     CDS             complement(144..539)
                     /locus_tag="IVD66_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP6146445.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(557..1519)
                     /locus_tag="IVD66_002254"
     CDS             complement(557..1519)
                     /locus_tag="IVD66_002254"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HAP6146446.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(1519..1731)
                     /locus_tag="IVD66_002255"
     CDS             complement(1519..1731)
                     /locus_tag="IVD66_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HAP6146447.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(1752..2450)
                     /locus_tag="IVD66_002256"
     CDS             complement(1752..2450)
                     /locus_tag="IVD66_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAP6146448.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(2470..3012)
                     /locus_tag="IVD66_002257"
     CDS             complement(2470..3012)
                     /locus_tag="IVD66_002257"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HAP6146449.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(3144..4148)
                     /locus_tag="IVD66_002258"
     CDS             complement(3144..4148)
                     /locus_tag="IVD66_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAP6146450.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(4145..5134)
                     /locus_tag="IVD66_002259"
     CDS             complement(4145..5134)
                     /locus_tag="IVD66_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAP6146451.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNLLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(5131..5937)
                     /locus_tag="IVD66_002260"
     CDS             complement(5131..5937)
                     /locus_tag="IVD66_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6146452.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            6103..7059
                     /locus_tag="IVD66_002261"
     CDS             6103..7059
                     /locus_tag="IVD66_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6146453.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(7136..7654)
                     /locus_tag="IVD66_002262"
     CDS             complement(7136..7654)
                     /locus_tag="IVD66_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP6146454.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(7742..7891)
                     /gene="rpmG"
                     /locus_tag="IVD66_002263"
     CDS             complement(7742..7891)
                     /gene="rpmG"
                     /locus_tag="IVD66_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAP6146455.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            8119..8565
                     /locus_tag="IVD66_002264"
     CDS             8119..8565
                     /locus_tag="IVD66_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAP6146456.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(8760..10655)
                     /gene="asnB"
                     /locus_tag="IVD66_002265"
     CDS             complement(8760..10655)
                     /gene="asnB"
                     /locus_tag="IVD66_002265"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HAP6146457.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(10980..11954)
                     /locus_tag="IVD66_002266"
     CDS             complement(10980..11954)
                     /locus_tag="IVD66_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAP6146458.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT         3969 a         2624 c         2108 g         3825 t
ORIGIN      
        1 ccttttcgct tagcttatat atgtagataa tagcacaaaa taaaaaaaat gaacggcaca
       61 actatccatt gcgccgttca tgtgatcttg gtcaaaatct aatgattgat tcggttttta
      121 aagctgtcat acaatcatct gttttatact tttttacttt tgatttttcc agaccatccg
      181 tcatatccac ccttaagtaa ataaatctct tgataacctg ctttacgtaa tttatttgct
      241 gtacggatgc tcaaactttt cttttgatcg taaatataga caggctggtc ttttcgaata
      301 gatcctaatg aatctttcaa aacagtgtaa gggatgtttc ttgcacctaa aatatgccca
      361 gcatcaaaca catctttttc gcgaacatcg attacttgtg cttttctcat tccttctcga
      421 aattcttctt ctgtcaaagt cgttgctgaa cgtttggcca ttactcgtag atagacttcc
      481 caaaggatga ttgcaagcac aatcaatagc aaaatgatat taattaccca taaaaccatg
      541 taatgcctcc gtttttttaa gcaaatttca aggctaatga ggcagcacca atgacaccag
      601 cttcattacc aagctctgct aatttgattt ttgttgattc tcttacttgc gggaaagtaa
      661 attctttaaa atatttctct acacggctac gtaaaaattc tcctgctgcc gatactcctc
      721 cacctaacac gatacttgac ggatttaatg tattccccaa gtttccgcaa gctaaaccta
      781 agtagaagca tacgcgatca acaaccatca atgcaaacgg atcgtcttct tgagccattt
      841 caaagatatc tttacttgtt acttcttctc cgttgtctag cattgctttc agttttgaat
      901 cccctgcgta ttcttctgcc aagaaacgac ctaggcgtac cacacctgta gcgctagata
      961 cagtttctaa acatccgcgt ttaccgcaag tacattcgaa cccttcagga tccacagtga
     1021 tatgtccgat ttctcctcca gctccgctca cgccgtgaat caaatttccg ccagcaacga
     1081 tacctccgcc aacacctgtt cctagagtaa cgaatacaac gtctggatcg ttttctccag
     1141 cacctttcca tcgttcacct aaagcagcaa cattcgcgtc attatcgata gcgaatttga
     1201 ttcctgttcc tgcctcgatc agttttttca caaattgaac ttctgtccag tttaagttat
     1261 acgcaccaat aaccgttcca gcttcgctgt ccacgcttcc tggggtaccc atgccgattc
     1321 cgataaagtc ttcggctttc atattatata aattcaaacg atgattgatt gattcaatga
     1381 tttcaggaac gatatgctta ccatcatcca aaatattggt atcgatgctc catttttgct
     1441 gaatctctcc ttctggtgtt aaaattgcaa attttgctgt tgttccacct aaatcaatcc
     1501 caataatctt cttgtccatt acaaatttcc tttctttcgg ctttcttcaa ttcggtgctc
     1561 tctttttaat atgcgccacg ctgtcatgta tgtatcatga tcaatcaaac ggctatcata
     1621 cagattacgc aattcgatag tcattaattc aatgtcatag atgcgtgcac ccacatagat
     1681 aaagatgcca aattttttga acagctgctg tacatcatat aagctctcca tctttaagca
     1741 cttccttcat attatacaag taaaccatat ttttttaaac ccagtaaaat acatattaca
     1801 aaaagaaata caaaaactag tgtagaaaga atcctttggt gtatcgaata gcttgtctgt
     1861 tgtttcggta gacccaaaac attccctaac actaatccgc caattagccc accgacatgt
     1921 ccccaaacat ctacagaggt atccagaaga ccaaaaacaa atgtcaacac aataaataaa
     1981 agaaaatgtc tgactagctg ctggatcgct gggttatgtt taaaatgaaa ccctaagata
     2041 aacaacgcac cgaacaaacc gaatatcgaa gtacttgcac caccagacag aacattcgct
     2101 tcgttaaaag caaagcttgc tgtatttccc attatcccgc tgaacatata aatcaagaaa
     2161 aaacgccaat ggccatagat tgcctcgatt tgctgcccca taaaatacag tatcagtgag
     2221 ttcattacga aatgcatcag tccaaaatgg atgaagattg gtgtcactaa acgccaccat
     2281 tcattgaagt gaacaagata aggaccatac attccggcat aataagggat ctcaagtcgc
     2341 ggaaataatt ccatcatgag gaagaccgct gtctgtatcc ctaaaaaagc ataggtccat
     2401 aacggtcgtc ttaaccatgc acgcaatttt atttgctgtt gataattcat gaaaacctcc
     2461 catttcattt tagtcaataa acaattgttg gatcttctga tcaaagctct ccggttgcca
     2521 ttgttcattc aattgttcac gaaaaacaag gctacatgtt tttttatgaa aattatttaa
     2581 ataccggtcg taataaccac cgccaaaacc gattcgataa ccggctctat tgtagataat
     2641 acctggtaca atgaggagat cgatcatctc cggcaaatag agcttctctg attgtggctc
     2701 aagaacacca aaactcgaac gtacaagaac ggactgttca tccatttcat aaaacgccat
     2761 ctgacgtttc ggcaaagttt taggtacaac tattttcttt tgttcttttt ctgctcgttg
     2821 gataaccggc tgtgtatcca gttcaaattc attcgataaa gtcgtcccta tcacttttgc
     2881 tgacttccag tactcgctgg cgaatagctg tttatagatt cgctgttctt tttccttttt
     2941 cttgccactt ttggccagat ttttcagctt ttcgattcct ttccggcgta atcttacttt
     3001 caattggtcc aaaaactcac ccttccttct ctcataaaat ggtataggaa aaaaagaaaa
     3061 atagcaatcg aactttcaaa taaatgcata aatagaataa aaagaagacc tagaaatgat
     3121 tggccttcct tttttaatga atttcaactg ttcagcgcgt gtttttgtct gataaaaagt
     3181 gcatacagaa aatatggcgc accaaaaagg gcaatcaaaa ttcctgtagg tacttcccca
     3241 cttagtagaa tcactctagc aaccatatct gcactaagca gaaaaatgga accgaacaaa
     3301 ccgctcagaa caaaggtcca gttattttct ttacgtacga ctagcttcgc agcatgagga
     3361 gctagtagtc ctacaaaaga taaactacct gtcaccgcta cactaccgct tgccaaagca
     3421 acagctaaca acaaaaggat tttttgactt ttagccacgt taaggcctaa tccttgcgcg
     3481 cgttcttgac caaatgatag caatacaatc ctctgtgcat aaagtcctcc tagcggaatt
     3541 aagataaccg cccatggaag caatgcccaa acataaggcc agctcgcacc ccagattgat
     3601 cccgctaacc atgcattcac aaatccataa ttttccttag ataattggat cgtgcatagc
     3661 aatgttaatg cagaaaggcc ggcattaacg gcaataccgg acaataagat tcgattcata
     3721 cccaaaaagc catttcgatc ataggccgca agatagacac agcaagcagc taaaacacca
     3781 cctagaaagg ctacaactag caatagaaac ggcagcgaat agtgcgaaaa gaaacctaaa
     3841 taaagcatca ctaaaaatcc tgctccggca ttaatgccca atatactaga atctgccaat
     3901 tcatttcttg ttactccttg caagatataa ccagaaacgc caagacaagc tcctgctaat
     3961 aaactgatca gtaatcgagg aactcgaaat tctctaacaa tcagcgccaa agaagatgat
     4021 tctttcccta tgaacgtggc aaaaagctga tccaggtaaa taaaaggcgt accaatcatt
     4081 aaactaccta tagacaggat gacaagtaca aaaagcaaga aatagaacgt ccaatatatt
     4141 tttttcaccg ttgttccctc cttacttgta tcagtaaaaa cggaacgcca atcaatgcaa
     4201 tgactaatcc aaaaggtgtt tcaaaagggg gattgatcat cctcgctgta aaatccgcca
     4261 acataaccaa tccaccgcca actaaaaaag agacaggtag aacataacga tagtccgttc
     4321 caaccattcc gcgaacaact ggcggaacca acagcccaat aaatgaaaca ggtccgacta
     4381 acgaaacggc aatggctgct aacactgcaa ctagacagaa aacaatcaac cgcgttcgtt
     4441 taggatgact tccaagagct aatgcatgtg tttcactcaa atgaatcaaa gatattgctt
     4501 ttcctaatga aaaagaaacc aaaacagcaa gtatatataa aggaaacaat actgctaatt
     4561 gtttccatgt gatattggca gctccgccta caaaccaaaa agcaagatcc tgctgcagat
     4621 taaagaattg ggtaagtgct tggctgatag cagtaaaaaa agaactaata gctacgccag
     4681 ctaaaatcag ctgtaaaaga ttcatgccca ttttcgaaaa ctgcaaaaaa ccaaatacga
     4741 gcaaagttac agcaaaagaa cctgccaatg acattagaaa cacagaaaaa tcagaagctt
     4801 taggccaaaa agcaaaacta agggccattg ccaacgaagc acccgcgttg attcctagta
     4861 agcctgaatc tgctaaagga tttcttgtca ctccttgcat caatgcaccg ctcaatgcaa
     4921 aacaactccc tacaagaaat gctcccgcca cacgaggcaa acgaatattt cgtatgattt
     4981 ggtgactttg ttttgatcta tcaaaatcaa acaacgcctg ccaaaaatct gcttttccca
     5041 cagtcgctgc gccatttgaa agagcaacaa aaaaaataat caaaagaaca aaacagacca
     5101 aaagcaggag tctatttttc ttcatagtcc tcataattga tcctcctgct cttttggcaa
     5161 caaatcatag gttagaaaaa ctggtttatt tgttcttgga agcgtgacaa tcgttgcatc
     5221 aatctcaaat atttttttca tacactcttt tgtgatcact tcttcaggtg taccttctgt
     5281 gatcaactta ccgtttttca ttgctaataa ataatctgaa aaacgtgaag catgattaat
     5341 gtcatgaatc gacatcaaga tcgttgtttg tttcatttga ttgatttcag tcaataactg
     5401 taggatctct aattggtgtg ccggatctaa aaatgttgtc ggttcatcca agatcaagat
     5461 atctgtttcc tgagcaagcg ccatagcgat ccagacacgc tgggtttgtc caccagacag
     5521 cgttgcgata tcccgcatac gaaatccagc tagacctgta gcatccaacg cccactcaat
     5581 tgcttcatga tcttgcgtgt ccatgccact gaacagtttt tgataagggt atcgtccgta
     5641 agatactact tcttctactg tcatacctgt agggtgttca ctagtttgtg ctaataatgc
     5701 aatttttttt gcaagttctt ttgaactgta tgtagagata tcagagttat tgacaatgat
     5761 ctttcctgat ttcacaggta gtatacgggt aaaacttttc aataaagtag attttccact
     5821 tccatttggc ccaatcaaac tagtgatttt cccttcagga atcgtaacag acatgttttc
     5881 aatgattttt ttgttttcgt agccggctgc aatgtcagct gctcttaatc tcgtcatttc
     5941 acccatcctt tcgctgaaaa tcattctcaa ttatgacgct gtttcaacat ttcgtcaagc
     6001 gctactttca tatctatagc caaatgaagc ggttgacagc gttcgaaata tcaggaataa
     6061 taaccaatga gaaagattct caattatgtt aggaggaaag aaatgaaatt aaaaacaaaa
     6121 gtattcacat tatctagcat attgctgctg gctggagtac tgagcgcttg ctccccctct
     6181 tcagataaag aaacagctac aactgccaat tcgacgactt catccaatag tactcataca
     6241 gtcacagata cacttggaca taaagtagag attccaaacg cgcccaaacg gatcatcggc
     6301 agttacttag aagactatct gattgcacta ggggaaaaac ctatcgccca gtggactgtt
     6361 ggcagtggtt ccattcaaga ttatctgcaa gatgatttaa aggatgtccc aacgatttct
     6421 tatgaccttc cttatgagaa agtgttaagc tttgagcctg atttgctgtt gatttcttct
     6481 tccgctactg tcgaaggcgg gaaatacgaa caatatagca aaatcgcgcc aacttatgtt
     6541 gtaaaaaacg gaacagatgt cacatgggaa gaacaactaa aagatgtcgg caaagctttg
     6601 gcaaaagaaa aagaggcaga aaaaatcatt tccgattatc aaaaatccat caagaaaact
     6661 cgagaagaac tagcagataa aatcgagaac aagacagctg cagtgttgtg ggtgaccaac
     6721 aactcagcct ttatggtcag caaaaatcgg tcaagtggaa gaatcgtata cgacgatctg
     6781 gaatttggtg ttcctgatct agtggaagag gtctccaaaa aagccacttc tgactggtct
     6841 gctgtttcct ctgaaaagct agctgaatta gatgctgact acatcatcct tgtgaacagt
     6901 gacaaagatg ctgccatgtt caatgaacca agctggaaga atctaaaagc agtgacagac
     6961 aatcatgtac tgcaattcgg acctgaatct agttggctat ataacggacc tattgccagt
     7021 caggaaatgg tcaatgatat caaagaaaaa ctaaattgat tttaactaaa aaaagcatct
     7081 tcacgattag tcgtgagatg ctttttttct tattaacaaa ctagacgcat agattttatt
     7141 cttcttttga agcaacccta ttttttactc tttcccattt ttgaaaacga tgggcatata
     7201 gattttcttg atccgttatc ccctcatact cctctataag ggcgaagtct gaaaaatcaa
     7261 tattcccaat atacgtatcg ccttcaaacg tgctatcgat caatgttcgc cagatccgac
     7321 cagtgtaagg aagaagttct tgaaaaatcc gactaccacc cgaaacatag atatcttctg
     7381 agatcgtttg actatacgac aaaagttcat cgatcgaatg cattacttcc gcattttctt
     7441 tcgtgcgaaa atttggttgc gttgtcaaca cgatgatatg gcgataagga agtgaaagat
     7501 cccccattcc ttcataggtc tttcttccca tcactaaaat tcgatccatt gtgtgttcgc
     7561 gaaagaaacg catatcattt ggcaatcgcc atggtaacaa accatttttg ccgatcagac
     7621 catttttatc ttgtgcccac atggaaataa acatattatc cgctccttat gattttagat
     7681 gttttgagat aaaaaaagtc tcaattcttt gaccagcaag gaattgagaa ctttaaaaac
     7741 attattttgt ttcacggtgc aaagtaactt tgcgttcgcg tgggcaatat ttttgttttt
     7801 ccaaacgatc aggattgtta cgtttgtttt tgcttgttag atagttacgt tctttacaag
     7861 aagtacactc taaagtgatg tttacgcgca tgtttttccc tcccattttt acaagaatcc
     7921 tctaagatga ctctcagact tgattatctt accatgattt tttctagatt gctagtgttt
     7981 ttcacgattt tgttaagtaa aactacttga cgataaatac aacggtttta cttctcaaac
     8041 aaaatctttt tctttttgta taaataccct tacacttgtt tatatagatt atgtttttta
     8101 ataaaggggg atactaatat gccatggaac atgaaggact ttcctgcatc aatgaaaaac
     8161 ttagataaat tgacaagaaa aaaagcaatc gacatcgcaa atgcattatt agatgaaggg
     8221 taccctgata accgtgcgat cccaattgcc attgatcaag caaaaaaatg gtatgaagat
     8281 gctagtgaat cagaaaaacg aactttcgaa aaagaaaaaa atccaagcaa gacggatgaa
     8341 cacgatacga atcctcgtgc tggaaaactg cttgattcag atgtgatcgt agaatatgag
     8401 gaagaacaat ggatcgtgaa atctaaaggg gcaaaaaagg caagcaacca ttttgataca
     8461 aaaaaagaag caatcgaaaa aggaaagcaa gtagcacaaa acaaagaatc aactttgttc
     8521 atttataaaa aagatgggac aaaagaaaaa gaaatcgatt attgaacata tgtaaagggg
     8581 ttgtgacgaa aatcgtgtca caaccccctt atgttcgaaa caatggtgtt cctctgccaa
     8641 ctccgaacca taagtcataa tatctataaa acgggaagag ctgttttttg aaattgtttc
     8701 ttatcactca gtgttaaacg gtaggagaaa acctcttttt tattgatatt tgattttcat
     8761 caaacagtca catagtcgat tgcttctgct tgcggaatcg tttcatctac aaagtagact
     8821 ttataccatg tcaagaaact gaagattgtc cagatttttc tttgctcttc tttacgtcct
     8881 tcgtgatggt catctagcaa cttcatgatt ttttcttgat caaaaaattc ttttgcaaaa
     8941 tctgcttcga ataatgcttt gacttgttcg tagccgtgtt cttctttcaa ccaagctttg
     9001 attggcacag ggaatcctaa tttcacacga ttcgaccatt cttccggaag atgtttgttc
     9061 gcagcttgtc tgaaaatatc ttttgtgttg ttttgattca ataaaaactt acttggtatt
     9121 tgttgagcca atttcatgac ttcgatatcc aataaaggta ctcggacttc caaagaactt
     9181 gccatagaaa gtttatctgc ctttaacaag atatcttttg gcatccattg atgaagatcg
     9241 acatattgca tcttattgac ttcatctttg attccttctg ttttctcgta atgaacagtc
     9301 atgatttcat ccacagatgg tgctgtttga tattttggtg ttaacacttc tgatgcttct
     9361 gattcttcga acactcgagc atgaccgata aaatattctt ttgcaggagc aagtgattca
     9421 tataaatgga tccgtccatg gaaatttttc atttttccga ttttacgtcc taaattatag
     9481 cgtgttcctt ttggtaattt tttcaatcct tgagcaatca cacggatgaa ttttgaattc
     9541 gtatggaatc catacgtttg gtatcccgca aacagttcat ccgccccttc tccagattgg
     9601 actacccgca cactttgtga agcaagattt gctaaaaagt acaaaggtac gcaagaagga
     9661 tttgaatcag gttcatctaa gtgatactgg atcaaaggga atgctttgaa cgacatgtct
     9721 ccgtcgatca ctgctgctgt attatctaag tccaatagtt cggttagttt tctggcttca
     9781 atcgcttcat tataggtttt atcatcaaac ccgattgaga aagaatgatc tggtttcaat
     9841 acagaggtta cataactgga atcaaccccg ctggataaga aagaaccaac ttctacatca
     9901 ctgaccgtat gtgcttcaat agaagcttga acggtttcgt cgattttttc gatccattct
     9961 tgtcgggaat gcgtttcttt tgtttcaaaa tctgcatccc aatattgctg aatgtctatt
    10021 tttccatctt tatacgtata ataatggcct tcaggcaaac gatagacatc tttgaagaat
    10081 gtttcgccgt ttaatggaga atattggaaa gtcatataag gtttcaacgc ttctttgttc
    10141 aattctttgt taaaatcagg atgaggcaga aaacttttga tttctgaacc aaacataaat
    10201 gttccgttca tttctgcata ataatatggt ttgatcccaa agtggtctct tgcaccgaat
    10261 aactcattct tttcattatc ccaaatagca aaagcaaaca ttccgcggat cttttgcaat
    10321 aattctgttc cccattcttc gtaaccatgc aaaaggactt ctgtatctgc atgtgtttga
    10381 aaaacgtggc cagctgcaat caattcttct ctcaaaggct ggtaattata gatttcgcca
    10441 ttaaaaataa tgatctttgt ccgatcttca ttgtaaatag gctgagtacc gccctctaag
    10501 tcaataatac ttaatcttct gaatcctaaa gcaacatgtt tatcgatata ttctcctgaa
    10561 ctattaggtc cacggtgaac gattcgatcc atcattgtat taataattgt ttttttgttg
    10621 tccttgtcgt taacaaaacc tacaataccg cacatttaac tttcacatcc taatataaaa
    10681 ttactgttta tttcattcat atgcatctta tcatagaata aatagcggac gaatattttc
    10741 tctcttacaa tttcgtcacg tgaaaacaaa agatgaaagt ttctgttttt acagaaaata
    10801 aagtcccaat atctaattta ccatgttttc ttttttgagg ctaccttatt ctcttcgtgt
    10861 taaaaaaata ttagtggatg ctatttccaa aaaaaccagc aaaaaaagac acgacctaaa
    10921 gatcgtgtct aattatgact gtatcagaaa atatgatacc aaacggatct attcattaat
    10981 taattgacat agtttatctg ttgctctttt atgactggat aactgaccaa ttcatgacga
    11041 tccaagtctt ctttattcat atttacagca gtaatttgac tgtcttcata cgtacgataa
    11101 taataaatcc ctttatcaac gttacagcaa gaagaataaa tcgtatattc gtattttctt
    11161 tctccagtat cgcatactcc tttttgttgc tcgactgagc ctagtatatg aaaaaattga
    11221 ctgatacttt cagattctga atcacctgat gcagcattca ttttagtaaa tgtggctttt
    11281 acaaatcgag aaacagaaga gagatctcca ggtaagccca atcctcccat cccacgacta
    11341 taaacattca agctgatctg gtttgaaaaa tgattttctg gtgttccatt tgatagcgag
    11401 cgataattgt tcagattaaa taattgataa tcaaatggcg gattatttgt caacacaccg
    11461 acaggattat catataaatg aagtccatct ttcatacttt caattactat cgatttttct
    11521 ttatcagcta ataaccagtg taaaggtgac aagggtagtt tttcactaaa atcgatattg
    11581 actagattga tagtagccaa taattcttta gcttcgtcta tggttgagca ttgccctagt
    11641 atccatggaa taaactcaaa tggtgcaacg ttatcttttc cttcttgtaa ttctttataa
    11701 tcagcattgc caggaaaatt cagtcctgcc atactcaacc ctttttcatt tgtagcctca
    11761 taatagagtg gatagttgga taccccagct gctattccta tcattgcata atgtttatct
    11821 aaatttttta cctttctaaa atcgaaacga taatttcttg gagtaatagt gaccacttca
    11881 ttataagaca tctcataatc aaaattcctt ccaaaataat ggtctttcgt tgcataagtg
    11941 attgcggtac acatcgtttc ccgtcctaaa acaaatcgtt tttacacttt tatcttacat
    12001 ctagtatttt ttttatcaaa aaaaggccaa agaagattga tttactagca tttataaaaa
    12061 atagtactca gggggaatca aaaaatattg taggttaaaa gtacaacaat aaggggctgt
    12121 gacaaaagtc ttgtcacagc cccttattcc gaacaaacgg tgttcaaaag cttgcatctg
    12181 cggtaataag cccaatcaaa cgaaaaaata ggaaaagcta tttttgtttg gccgttctta
    12241 ttacttgatg caggacagct tcttcacaac ctctaatcgt tgatataagg aaggtacagg
    12301 atttgaacct gcgcgccggt attagccggt tcgccggatt tcgagaatag ggtttaaagc
    12361 tgattttaag tgtttttcgc ttattatcag ctttttatta tctaaaaaaa caacttttag
    12421 agacatccat atactgcttg ggggagtcaa aaggggagtc atttttatat tttattcgca
    12481 atttaaatca cttagagtat gtacactgta ggactcgagc ctacga
//
LOCUS       DACBZK010000076        12301 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.079, whole genome shotgun sequence.
ACCESSION   DACBZK010000076 DACBZK010000000
VERSION     DACBZK010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12301
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.079"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            31..1062
                     /locus_tag="IVD66_002267"
     CDS             31..1062
                     /locus_tag="IVD66_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAP6146459.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGKLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            1059..1826
                     /locus_tag="IVD66_002268"
     CDS             1059..1826
                     /locus_tag="IVD66_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAP6146460.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            1926..3494
                     /gene="liaX"
                     /locus_tag="IVD66_002269"
     CDS             1926..3494
                     /gene="liaX"
                     /locus_tag="IVD66_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HAP6146461.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            3794..4111
                     /locus_tag="IVD66_002270"
     CDS             3794..4111
                     /locus_tag="IVD66_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HAP6146462.1"
                     /translation="MKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVAF
                     GSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDEW
                     SDF"
     gene            4111..4461
                     /locus_tag="IVD66_002271"
     CDS             4111..4461
                     /locus_tag="IVD66_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HAP6146463.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            4628..5566
                     /locus_tag="IVD66_002272"
     CDS             4628..5566
                     /locus_tag="IVD66_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HAP6146464.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            5581..6411
                     /locus_tag="IVD66_002273"
     CDS             5581..6411
                     /locus_tag="IVD66_002273"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAP6146465.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            6455..7480
                     /locus_tag="IVD66_002274"
     CDS             6455..7480
                     /locus_tag="IVD66_002274"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAP6146466.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            7495..8433
                     /gene="galU"
                     /locus_tag="IVD66_002275"
     CDS             7495..8433
                     /gene="galU"
                     /locus_tag="IVD66_002275"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAP6146467.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            8558..8998
                     /locus_tag="IVD66_002276"
     CDS             8558..8998
                     /locus_tag="IVD66_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HAP6146468.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            9001..9603
                     /locus_tag="IVD66_002277"
     CDS             9001..9603
                     /locus_tag="IVD66_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAP6146469.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(9662..10768)
                     /locus_tag="IVD66_002278"
     CDS             complement(9662..10768)
                     /locus_tag="IVD66_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAP6146470.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            10978..11979
                     /gene="ccpA"
                     /locus_tag="IVD66_002279"
     CDS             10978..11979
                     /gene="ccpA"
                     /locus_tag="IVD66_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HAP6146471.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
BASE COUNT         4088 a         2118 c         2595 g         3500 t
ORIGIN      
        1 cttttcatca tttcatagaa aggataaaga atgcaaaaaa aaattagcat catcactata
       61 ttttttattt gtgtgcttac ttcatgggtt attcagcatc aagccgcttt atatgaagta
      121 cctgtcatcg agatagaaaa agtacgaata aaagaggatc atcaattgat tacaggaaaa
      181 ctgatgaaca cggatcaaaa aggagaatcg atttatttat cggttcctta tcaaaaaaat
      241 caaatagaaa cagcaaatat aaaagcgaga caaatgtatc tagtccaaat gcatggagat
      301 gaatggcagc tagtagcaaa aaaaaatgat ggctggcttt tcttcttcac aagtatcttc
      361 attggcgcca tgttgcttat tggtggaaaa cagggtctat ttgctttagg aagtctcatc
      421 atcaatatcg ttttactttt acttttgttg ctcatcttta ctaaaacaga agggatttct
      481 ctattaaata tatctatcct gttcgtcgtt atagggatga ttattagcat attggcttta
      541 gatggatgga atagaagcag tataatcaaa atttcagctg cagttacgag tgttttttta
      601 gcatttttta tttgtctttt gacaatgaat cattggaaag accaaggact gcgctatgag
      661 gaactgaatt atctgacacg accgtatcgt tctgtttttc tttctagcgt actgattgga
      721 acagctggag gaacactcga taccgttatc acagtcattg cgacattaga agaattgact
      781 aagcgacaac cagaaataac agcgaaacag ttatggcttt caggaaggca agtgggtcga
      841 gatgtgattg gctcgatgac caatatcctt ttgttcgtct atatcagtgg gtcagttcca
      901 tcgcttcttt tatatttagg aaatcaatgg tcgttcaaag aaacgataga acagcattta
      961 tcattggaat ttttacgcgt cattgctggc agcttaggaa tagtattatc gatccctatc
     1021 tcggtcctct tttttctgac tgtaaggagg ctgaaacgat gaatgtactt attatacttg
     1081 ttgggatttt agcaatcagc gtgctactta ttggcggtac gcaaggtatg tatattcttt
     1141 taggcttatt catcaattta gggatctttt tcctgttgtt attcggttat catcagaagt
     1201 ggccgatact ggcattgtcg gtcataggat ttttattgat tgctgtggtt atcttatttt
     1261 ttatcaacgg ttataatcta aaaatgcgtg cagcttttgt gagtatactg atctttttat
     1321 tttgtttcct actattgctt cctatcactg attttttagc aatccaaggt tttacatcgg
     1381 tagaactaga agaattatct ggcttagata agactttagc gattgatttt agattactta
     1441 cgagatcgtt gcttctgatt agtcttagtg gtgctgtttt agatgcgagt gtagcaattt
     1501 ctagtgggac attcgaagta tatcaggcaa atccgcaatt atctttttac caattgcgcc
     1561 attctagttt cgctattgct aaaaaaatat tggcgtcaac agtaatgaca cttctttttg
     1621 cattcatggg aagttcttta gcgttgatcc tctggtttat tgatttagac attccttttc
     1681 agcaagtgat caatgaaaaa tcatttgttc tagaatatac gatggctatt cttaccacat
     1741 tgtccgcact acttgttctt cctttaacct gcgtgactac agcatatctc tttacaaaaa
     1801 agaaagaaca actcaagatg gagtaaaagt tacaacttaa gtcctatgac atttttactg
     1861 aatcagtgca taatatggat gtaaggaaaa gcttgcaaac aattttgctt aaggaggcaa
     1921 tttccatgaa agaaagagaa cgtattttag atttagtgaa aaaaggaatc ctttcgactg
     1981 aagaaggctt agatttatta gaaagcatgg caactgaaaa agacgaaaag caaatcaaaa
     2041 aagaagcaga caaggtaact gctagtcata aagaaaaaga tcaggcaagt caattgatcg
     2101 ataaacttga aaacggcgaa gaagaaattt ctgagccagt tgatccaaag gaaagagaaa
     2161 gacaagatca agaaaactta gaaaagatct tagatgaact agcaactgaa gcgaataaaa
     2221 cttcggcgcg tctagatgaa gtaaatgctc aattcgctga caataaggca gcacgcaatg
     2281 agaaacagga agcattgatg cagctgaata caaaagaaga attaggcgag ttgacagaag
     2341 aagaattagc acagcgtcag acgttagaag cagaaatcaa agaattagaa gctagtggcg
     2401 atacactgtt agaagaacaa ttgaaattag aagcagaatt aaaagatatc cgtaagaatc
     2461 aatggtctga gaaaaaagaa acgtttactg ataagtttga attgccagat gattggaaag
     2521 atcaagcaac agatacactg aatcaagtag gcgaaaaaat gtcagaagct ggatcacagt
     2581 taggcaaatt cttgaagaaa acattccaaa ctgtttcaga aacagtgaat gacaacatgg
     2641 aatggaaaga tgtcagctta cgtgtccctg ggattgcgac aacgaaattt gagcatgaat
     2701 tttactatga agctcctgca gcaagtatcc ttgatatcaa ggcagcaaac ggaaacgtga
     2761 cgttaaaaac gtgggacagc aacgatgtga aagttgaagc taagatcaaa ctttacggaa
     2821 aaatgggtgc tgaaccattt gaagcattct ctgaacggag ccagattgag gttaatgaag
     2881 atcatatctc cttccaaatt ccaaataaac gtgtgcgtgc agaccttgtt ttctacttac
     2941 ctaaacgagt atacgaccac gcagctatta aacttctaaa tggcaacatc atgattgaaa
     3001 cattggaagc taaagatatt tatacaaaat ctacgaatgg taacatcatc gtggaccaat
     3061 taactgcaac gatgctggaa gtagaaggtg taaacggcaa tatcgatatt cgaaacggga
     3121 acatcttaga ttctattatc gaaacagtaa atggtacagt gacatttggt gcgacagcag
     3181 aaaacctttc tgtgtctttg gtaaatggtg atgtacgtct tacgattaaa gaagataatt
     3241 tgaaaaaagt agaagcaagt tcagtgaacg gaaatgtcaa agtcgcttta ccagatggca
     3301 tcggtttgga aggacatgct aaaacaagtc ttggaagtat caacagccgt ctgtccaatt
     3361 acgaagtagt tcgtgagaaa aaagaacgga caaaccaaat gttgcaattc cgtcgtgttt
     3421 cagatggtga aatcgcgcaa gtgcaacttt caacgacaac aggaagtatc tatttaaaag
     3481 atacagataa ataaagaggt tgtgaaagag atgttcagcc ttgagcaata agaagcgatt
     3541 ttgtaaaata gcttccccta ttttacaaaa ttgtgcctta ttgccgatag tctatctctt
     3601 gaacaccgtt taccaagaga ttatgaacct gccaattatc gccgagtcac aaggaataat
     3661 ttcagaaaaa gctcgtcacg ttttatgaat atggtaattt gtgaccgaga attttgcaga
     3721 aagacaccga ttaagaagaa ggttgtcaca acgattttct tcatttaaaa tagtagaaca
     3781 gaggtgagac atgatgaaaa aaaagttgac aaaatctaat aaaaatgttg ttttgacagg
     3841 gactttagca ggaataggag aatacatcgg gattgatccg actgttatcc gtgtgcttta
     3901 tgtattcctg agcttagttg cttttggaag tccaattatt ttatacattt tattagcttt
     3961 gattatccca tctgcgcgtt ctgcacgaac aaactatgga cataacaatg catattatga
     4021 aaaaaacaat tatcgtgaac aaactcgtga acaaacaaaa aaacgcaaag aagcggaaaa
     4081 aatcgatgat gacgaatgga gtgactttta atgtcgtact ttcaacgtat tttagttaat
     4141 acgttaacat tcatatcatt ggctgttctt tttcctgcga tggtccatgt gagcagtatt
     4201 tggacggccg ttcttgccag cttcgtattg tctgtgttga atatgtttgt caaaccgatt
     4261 ttgacgatac tgtccctgcc ctttacatta gtcacattgg gattgtttac gtttgttatc
     4321 aatgcagcga ttcttaaaat gacctccttt tttgtgggag cagaacattt tagtttttct
     4381 tcattcggtg cagcgttgtt agtagctatc ttgatgtcgc ttgtcaatgt aattgtcagc
     4441 gaacataaca gtagaaaata aaagaaagct gtgccgaact atcggcgcag tttttttatt
     4501 tagaatcagg aatgcgtttt ctattacatt ggtaattaaa taaaaacgtt ttttttaatt
     4561 ggtagtactt ttggctagac aatgataaaa tgatagagaa cactctaata gaaatgaggt
     4621 agcatgaatg tcagaagttg taaaagttag ccaattagtg aaaaaattat ctttggaaat
     4681 cgtgacaggc gacgagaaaa gcttagaccg tgtcatcgta actggggaca tctcacgccc
     4741 aggactagag ttgactggtt attttaatta ttattcccat aatcgtttac agctatttgg
     4801 cagtaaagaa atcagttttg cggaacggat gatcccagaa gagcgtttga tcatcatgag
     4861 aagattatgt agtgaagata tgcccgcatt tattatttca agaggattac cagctccaga
     4921 agaaatgatc caggcagcaa atgaaaatgg gatagctgta ctgcgttctc ccatctcaac
     4981 ttctcgttta ttaggagaat tatccagtta tttagatggt cgccttgccc ctcgaacaag
     5041 tgtccacggt gttttagtgg atgtttacgg attaggtgta ctgattcaag gtgacagtgg
     5101 gataggaaaa agtgaaacag cgttggagtt gatcaaacgc ggccatcgat tgatcgcaga
     5161 cgatcgagta gatgtttatc agcaagatga attaacggtg atcggagaac cgcctaaaat
     5221 cctggaacat ctgattgaaa tccgaggaat cgggatcatt gatgtaatga atctttttgg
     5281 tgcgagtgcg gtacgtggct ctatgcaagt ccagttggct gtttatctgg aagcatgggc
     5341 aaaagataag aaatacgacc gtctgggctc tgaagacacg accgttgaaa tcgcggaagt
     5401 gggcattcca caaataaaaa tccctgtcaa aacaggacga aacgttgcaa tcatcattga
     5461 agtagccgcg atgaatttcc gtgcacgtac aatgggcttt gacgcaacga aaacatttga
     5521 agaaagatta agtcgcttga ttgaagaaaa ctcaggcaac gactagcaag gagtgacaat
     5581 atgttagcac aaatcaatcg agttgctttt gagcttgtag ggattcctat ctactggtat
     5641 gcattgatca tcgtatcagg tatcattatc gctatgtggc ttagcagcag agaggctgtt
     5701 cgggtaggat taaaagcaga tgatgtgaca gattttatgt tgtggggatt gcctatctcc
     5761 attattggcg ctcgcttata ttatgtttta tttgatcttc cccagtatat agctgatcca
     5821 atccaaatat tcaatatccg ttcaggaggc ttagctattt atggcggact gattgcaggc
     5881 gcgatcacgc tgtatttttt tactaaatat cattttattt ctttgtggac ttttttagat
     5941 atcgctgcac caagtgtatt attagcacag gcaatcggtc gttggggaaa tttcatgaac
     6001 cacgaagcat atggaccaga cacgacgcga agcttcttag aaagtctgca tttaccgcaa
     6061 ttcatcattg ataatatgta tatcgaaggg atctatcgtc aaccaacatt tctttatgaa
     6121 tcactttgga gtttgattgg atttattttg cttttgtttt tacgaaagaa accacacctt
     6181 ttgaaaaaag gcgaagtcct tttatgttat ctaatgtggt atagtttcgg gcgtttcttt
     6241 attgaaggat tacgtacaga cagtctttac tttttaggtg tgatccgtat ttctcaatta
     6301 ttatctgctg tgttatttgt cggtacattg attctattta tttggcgcag aaaaaaagga
     6361 aatttaccgg attatgaccg ctcattagga aaaaatcaac aaattatctg atttttagag
     6421 cgttaaaaat gaaaaaaatt tcaggagtgg taaaatgaat tatagagtag cggttttagg
     6481 accaggctct tggggtactg ctttggcaca agtcctcgcc gaaaacggac atgacgttcg
     6541 gatttgggga catcgtgctt cacaagtaga agaaatcaac acccaacaca cgaatcaacg
     6601 ttatttacca gatcattatc tacccgattc catccaagca ttcaccaata tggaagatgc
     6661 agtaaaagac gcagatgcgg tgctattcgt cattccaacg aaagcaatac gttctgttgc
     6721 aaaagaacta gtgcctaaat tgaatacaaa gccagtgatc atccatgcaa gtaaaggatt
     6781 agaacaggga acacataaaa ggatctctga catcttgtta gaggaaatcc cagcagaaaa
     6841 aagaaaagct gttgttgttc tttctggacc aagccatgca gaagaagtag caaaacatga
     6901 catcactacg atcacagctg caagtacaga tgcaaaagca gcaaaatatg tacaagagct
     6961 gttcatgaat aattattttc ggatctatac caatcctgat gtgatcggtg tagagatggg
     7021 ggcagctttg aaaaatatta ttgctattgg tgctggcgct attcacggct tagggtttgg
     7081 cgataatgca aaggcagcaa tcatgacgcg cggattagct gagatcagcc gtttaggtgt
     7141 agcaatgggt gccaacccgc tgacctttat cggattaagc ggaataggcg atctagtcgt
     7201 tacttgcaca agtgttcatt ctaggaactg gcgcgcaggc aacttgttag gacaagggca
     7261 gcccctagaa gaggtgctag ccaatatggg aatggtcgtt gaaggtgtga atactaccca
     7321 agcagcgatg gaactagccc aaatgatgga aatcgaaatg cccatcactc aaacaatcta
     7381 tgaagtgctg tatgaacaaa aagaaatcaa aacagccgca aaagaaatca tgttacgtga
     7441 tggaaaaaaa gaaaatgaat tctcattaac aattttttga aggagcgaat gtatatgaaa
     7501 gttaaaaaag cagttattcc agcagcagga ttaggaacaa gatttttacc agcaacaaaa
     7561 gctatggcaa aggaaatgtt gccaattgtt gataaaccaa caatccagtt catcgttgaa
     7621 gaagcgttga aatcaggtat cgaagacatc ttgatcgtta caggaaaagc taaacgacca
     7681 atcgaagatc actttgattc aaatattgaa ttagaaacaa acctaagtga aaaaggaaag
     7741 accgaattat tgaaattagt agaagaaacg acagatgtca acttgcattt catccgtcaa
     7801 tctcatccaa agggtttagg acatgccgtt cttcaagcaa gagcctttat tggaaatgaa
     7861 ccatttgtcg ttatgctagg cgatgatata atggaagacg aagtaccatt gacacagcaa
     7921 ttaatcgatg attacgaacg tactcatgct tctacgattg ccgttatgca agttcctcat
     7981 gatgaaactt caaaatacgg aattatcaat ccaggagaag tattggaaga tgggttatac
     8041 aatgtcaaaa actttgttga aaaaccagat ccaagcaaag caccaagtga tttagctatt
     8101 attggacgtt acttattgac tccagaaatt tttgatgtat tgtccgagca acaaccagga
     8161 gccggaaatg aaatccaact aactgacgca atcgatacat tgaataaaac acaacgcgta
     8221 tttgcccgta aattcacagg taaacgttac gatgtcggtg acaaatttgg ttttatgaaa
     8281 acaagtattg aatatggtct aacacatcca gaagtaggtg cacctttacg tgagtacatc
     8341 ctgtctttag gtaaaacatt agaagcagaa ggaagcaaga tcgatcataa tccaaaagga
     8401 ataacagaaa tcaaagaaga aaagaaaaaa taaccctttt ttctaacgag cttcagctgc
     8461 taattgaata aaaagtagtt gaagctcgtt tttatttgtt taaaaaacac gaaaatgcta
     8521 tccttataga aaagagagac aagaagggag tttgatcatg tcaggaggag aaattgcagg
     8581 attgatcgca gcaatcgcct ttgcgatact tgtcgttttt atcgttcgtg tgttgttgca
     8641 agtttctaaa actttagaaa aagtagatca gactgtagca gaagcaaata cgacgatcga
     8701 aatcgtcaca aaagacgtag atcttttgtc tagacaagta gaaggcttac tggtcaaaag
     8761 taatgaactg ctcttggata tcaatggaaa agtcgcaacg atcgatccat tgttcacagc
     8821 agttgctgat ttaagtgaaa gtgtatcaga acttaatcat tctagtaaaa acatcgcgac
     8881 gaaagtcggc ggaatcggta aaacgacagc taaagcgacg gttgccggaa aagtcggtgg
     8941 gacagcgatg aaatttttta aaaacaaaaa acatactgaa acgacaggag gaaaataaaa
     9001 atggctaaaa aaggtggatt tttattaggt gcagtagtcg gaggcacagc cgcagcaatc
     9061 gccgcgttat tgttagcacc aaaatctggt aaagaacttc gggatgaatt agctgcccaa
     9121 gcggatgatt tgatggatat ggcttcagat tacacagata tggcgaaaga aaaatcgact
     9181 gagttaacag gtattgcaaa agaaaaagcg caagatcttt ctcaacaagc aggtgatcta
     9241 gcaggtagtg tcaaacaaaa agtaagtgaa tcagcagatg aagcaggaag tgaatctgac
     9301 gatatcttgt taaatcttaa agaacaatca gctgacttat ctaatcgttt caaaaaaacg
     9361 gcagaagata tgaaaaaacc tgcagatgaa ttaggaagta ttgctaaaga tacttcagaa
     9421 gatatcatga ttgatgtaaa agacgctgct ggtaaagcag gagatactgt caatgaagga
     9481 atgtcagaag caaaaccagt tgcagatgac tcaaaagaaa tgatgaaaat ggcaaaagaa
     9541 gatgcgaaag aagctaaaaa agaaataaaa gatacaatga cagattcatc tacaaatcac
     9601 taaaatcaca aatttataga ataaaaaggt gggagcggac tagctctcac cttttttact
     9661 cttatttttc taaaacaagt aattcttttg gtgtagtcgt gaatggcaca cagccatcgc
     9721 ttgtcacata tacacagtct tcgatacgta cccctacttt ttcaggaata tagattcctg
     9781 gttcaagaga gaagcacatc ccttcttcga ttactaagtc atttccttct acaagggaag
     9841 ggaattcgtg gacggttgtt ccgatcccgt gacctaaacg gtgattgaaa tattcgccgt
     9901 agccatagct gttgatcacg tttcgtgcga tttgatcaag ttcacctgct gtcacacctg
     9961 gacggacggc ttcttgtgcg gcaagctgtg cttcaagagt gatgttgtag attttttctt
    10021 ggaagtcggt tggtttttga taagcaattg tacgagtagc atcactgcaa tagccattcc
    10081 aaacaacgcc aagatcgaat aacacaagtt cattcggtga aatcttcgta tttcctggtg
    10141 taccatgagg gcttgcagca tttgctcctg caaggactaa tgtgtcgaaa gacatttgtg
    10201 aaacaccttg ttttttcaat tggtattcaa tttctgcaat gatcgcttgt tcagtcacgc
    10261 cttctttcac tgctttaaag ccaatctcaa atgcaacatc ggcccattta ccagcttcga
    10321 tcagtttgtc tttttcctct agagttttga tcagttgtag acgttggatg atggaagtta
    10381 gatcagtgta agaatccgtt cccgtcaaga tatcagagat agcatcgaag cgctcgacag
    10441 tcaaggcgtt cttttcaatc cctacattgc caggctgacc atagcgagca cgaagttctt
    10501 ttccgatgat ctcccaaggg ttttcgctgt ctaaatagcc acggacatca tacgcccaac
    10561 tactgttttg agcatcttca acttccaaag caggagtgaa aaggaaagga tcttgttcaa
    10621 gagggataaa aagagctagt acacgctcat gaggatcact ttcgtatccg gaaaagtaag
    10681 cgatgtggcc agggtcgctg atataagcca attcgacttg gtgttgtgcc atccattgac
    10741 gtagttcatt gatttttacg ttattcattt ggcaacctac tttctaaatt aattttgtat
    10801 tcaataattg taccactgat ttattaaaag accaacgttc taaaaactga aaaaagtaaa
    10861 aattttcatg aaaacagaga taaaacggtt gcaattcttg agattatttg atattctatt
    10921 ttagaaatgt aagacgtatt ttcagaaaac atataaaata tgaataggag aacacaaatg
    10981 gaaaagcaaa caatcactat ctatgatgta gcgagagagg caaatgtttc gatggctact
    11041 gtttcacgtg tcgtaaatgg caatccaaac gttaaaccag caacaagaaa aaaagtcttg
    11101 gaagttatcg atcgcttgga ttatcgtcca aacgcagttg cgcgtggctt ggcaagtaag
    11161 aaaacaacaa cagttggtgt aatcatccct gatgtcagca atatgttctt tgcttcttta
    11221 gcacgtggta tcgatgatgt ggcaacaatg tacaaataca atattatctt agcaaattca
    11281 gatggcaacg accaaaaaga agtcaatgta ttgaataact tactggctaa gcaagtggac
    11341 ggcgtgatct tcatgggtca ccatatcaca gacgaaatcc gtggagaatt ttcacgttca
    11401 aaaactcctg ttgtattagc tggctctatt gatccagatg aacaagtagg tagcgtaaac
    11461 attgattatg tatccgcaac aaaagatgca gtaaacaaat tggcaaaaag cggcaataaa
    11521 aaaatcgctt ttgtcagtgg tgcgttgatc gatcccatca atggacaaaa tcgtctgaaa
    11581 ggctataaag aagcattaag cgaaaataac ctaccatata gcgaaggatt gatctttgaa
    11641 gcacaataca acttcaaaga tggtctatct ctagtcgatc ggatccataa tagcggtgca
    11701 acagctgtct atgtttcaga tgatgaatta gccatcggta ttttggatgg tttattagac
    11761 cgtggcgtga aagtaccgga agaattcgaa atcatcacaa gtaacaattc actactgaca
    11821 gaagtagctc gtcctcgttt aacaagtatc acacaaccat tatacgattt aggggcggta
    11881 tctatgcgcc tattgacgaa aatgatgaat aaagaagaag tcgaagaaaa aacgattatc
    11941 ttgccttatg gaatcgaaga aaaaggatct acaaaataat aaaaggacaa ccattcagag
    12001 gttgtgtgcc tgccgtttaa ctctgcgtta caaggagcaa tttcaaaaaa cagcatctca
    12061 tgtttgatga atattgtgac tcgtgattcg gagttggcag gagaacaccg tttatttggg
    12121 aaaaggggtt atgacaaaat tttgttataa tccttttttt gtgtcttaaa aaagagagaa
    12181 agtggttgaa attacattta tcgtatataa aacaatccgt gtatagatgc tgcattttgt
    12241 tcaccaccat caaaaaaata agggactgtg acaatactat tgtcacaatc ccttattact
    12301 g
//
LOCUS       DACBZK010000077        11891 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.080, whole genome shotgun sequence.
ACCESSION   DACBZK010000077 DACBZK010000000
VERSION     DACBZK010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11891
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.080"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(94..969)
                     /locus_tag="IVD66_002280"
     CDS             complement(94..969)
                     /locus_tag="IVD66_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAP6146472.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(1051..1842)
                     /gene="codY"
                     /locus_tag="IVD66_002281"
     CDS             complement(1051..1842)
                     /gene="codY"
                     /locus_tag="IVD66_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HAP6146473.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(1860..3260)
                     /gene="hslU"
                     /locus_tag="IVD66_002282"
     CDS             complement(1860..3260)
                     /gene="hslU"
                     /locus_tag="IVD66_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HAP6146474.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(3274..3822)
                     /gene="hslV"
                     /locus_tag="IVD66_002283"
     CDS             complement(3274..3822)
                     /gene="hslV"
                     /locus_tag="IVD66_002283"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HAP6146475.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(3859..4764)
                     /gene="xerC"
                     /locus_tag="IVD66_002284"
     CDS             complement(3859..4764)
                     /gene="xerC"
                     /locus_tag="IVD66_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HAP6146476.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(4962..6338)
                     /gene="trmFO"
                     /locus_tag="IVD66_002285"
     CDS             complement(4962..6338)
                     /gene="trmFO"
                     /locus_tag="IVD66_002285"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HAP6146477.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(6307..8385)
                     /gene="topA"
                     /locus_tag="IVD66_002286"
     CDS             complement(6307..8385)
                     /gene="topA"
                     /locus_tag="IVD66_002286"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAP6146478.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(8507..9364)
                     /gene="dprA"
                     /locus_tag="IVD66_002287"
     CDS             complement(8507..9364)
                     /gene="dprA"
                     /locus_tag="IVD66_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAP6146479.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQNGAVCTVSG
                     EDILAEFKE"
     gene            complement(9420..10187)
                     /locus_tag="IVD66_002288"
     CDS             complement(9420..10187)
                     /locus_tag="IVD66_002288"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAP6146480.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(10180..11040)
                     /gene="ylqF"
                     /locus_tag="IVD66_002289"
     CDS             complement(10180..11040)
                     /gene="ylqF"
                     /locus_tag="IVD66_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAP6146481.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            11300..11698
                     /locus_tag="IVD66_002290"
     CDS             11300..11698
                     /locus_tag="IVD66_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP6146482.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
BASE COUNT         3138 a         2581 c         2081 g         4091 t
ORIGIN      
        1 aaatcgatgt cacactccct tattacttac aggatagctt ttttacacac cttggtaaac
       61 ggtgttccct gctaacttct cggtcacaac ctcttacttc actgtgatgg aatattttgt
      121 cttgaagatt tcatgggcac ctagttgatt gatccctact ttttccatca agtttccact
      181 actgttcacc gtgtcagcga ttccgcacca cggttcgata caaacgaaag gcgcttcttt
      241 tggataagga gaccagatcc ctacataagg catatcttta tagcttaaag ttacgctatg
      301 ggaagatttt tcacttcgaa tggcgtacgc atttagaccc cttgtttcaa aaaccaaggc
      361 atcttgctca aaaagttcac gattcaaagc cagattcgta tttgtctgac ctaacgtctt
      421 ttgatccata tcgatgaatg ggcctttcaa tggtaggcgt aatcttgatt tcaatggaga
      481 aaatgccaga tagaaatctt caaatgacaa tccttcttca agaggtacat tgaaagcagg
      541 atgtccaccg atagaaaaga acatttcttt ttcaccggta tttgccactt gataatgaac
      601 cgtgatgccg tctcctccta attcatagct gatcactaat tcaaaatcaa atggatactt
      661 ttctaatgtc tccggcgtac tccttaagat gaaactagcc atttcttgtc catgttcaat
      721 gacttcaaaa tccatatccc gagcaaatcc gtgttgcccc atttgatatg ttttcccttg
      781 ataaacatac tgatcatctt ttaaacgtcc aacaaaaggg aataaaaccg gtgcatgtct
      841 gccccaatac gctggatcac cttgccagat atactctaaa ccatgttctt ttgatttcag
      901 actgatcaat tccgcaccgt gttcagcgat ttcggcgatc agctggtcat tttgaataat
      961 aacagtcatt gccattcctc caacttcgac ttacttttta aaatgggaag gctggaacaa
     1021 acatttctat ctgccccagt ccccttactt ctaataactg tgttttgcta actcgtcttt
     1081 aaaacgggaa ttcaatactt ttaaataagt tcccttcatg cctaacgaac gagattcaat
     1141 gattccagct gattccaatt ttcgtaaagc attgacgatc acagaacgag tgatgccgat
     1201 actatcggca atattagaag cagtcagacg accttcatct ccatccaatg cttcaaagat
     1261 agcttgtaca gccttcaatt cgctataaga taatgtgttg attgccattt ggacagccgt
     1321 tgcactccgt acatctgctt cgatgcttcg agacttctga taaaggatct gcataccgac
     1381 aaccgtagct ccatattctg ctaagactag atcgtcatct gcaaacgatt gttccatacg
     1441 agataagata atcgtaccca aacgttcgcc agctccaaag atcggaacga cagtcgtcag
     1501 accaaatgga tatttctctc ttgactctac cggaaatgca gtaatatcac tagtaattgg
     1561 gatattagct tcagttttca tcaactgtgc cactgtatca gtataagatt caggaaattg
     1621 tttctcaaca aacattgttt tgattcgttc attgttcaca tcgtgacgtt cattataacc
     1681 tagtaatact ccgtcacttc ctatgatata ggtgttgctg tcaagaatac cacctagtgt
     1741 gacagccatt ttatcgtaag gcaaatctgc ttgcatgtca aaagtattct tttgctgcaa
     1801 aagtgtgttt atcttgcggg ttttcgttag caagtctgtc attgtcgtcc tccgattttt
     1861 tataaaatat agcgacttaa atcttcattt gccgcaattg agccaagttt gtcatccaca
     1921 tatgcttctg tgatcgttat ttctcccatt tgcatatctg gtgcttcaaa taatagatct
     1981 tctagtagtt tttccaaaat ggtatgcagt ctgcgtgcgc cgatattatc tgtgtcacgg
     2041 ttgacatcga aagcgatttg agcgatccgt tcaattgctt cttttgtaaa cgtaactgac
     2101 acattttctg taccgatcaa cgcgacgtat tgttttacta aagcattatt tggttcggtc
     2161 agaatcttca caaaatcttc agctgtcaaa tcatctaatt ctacccgtat cgggaagcgt
     2221 ccttgaagtt ctggaattag atcacttggt ttagacaaat ggaaagctcc tgaagcaatg
     2281 aataggacgt gatctgtttg gatgatcccg tattttgtgt ttacttgtga accttcgaca
     2341 attggcaata tgtctctttg gacgccttct ctggatactt ctccagattg ctgtgattta
     2401 gaagtgatct tatcgatttc atcgataaaa ataattccac tttcttccgc taatttgatt
     2461 gcctcactat ggatatcagc atccttgact aattttgctg attcttcctt gatcaataac
     2521 tctaaagctt ctttgactgt taccgtccgt tccacttttt tcttcggtgt caaagcacct
     2581 agagtttcat ttaggtcgat ccccatttgc tccaatccat tgttcatcat tggtgcaggt
     2641 ttcttttggt cttcaacttc aatggttact tcacgactat ccagtaaacc cttttgtagt
     2701 tgttccaaga ctgtacggcg attgattcga atatcttctg tcacttcttc ttgcggttca
     2761 gcggtatttt gctgactagc attaaaaaga ttcatcattt gttcaaattg attagtggat
     2821 tgtttctgtt cttttttgat accaggtacc aagattttta ccaaacgttt ttctgcattt
     2881 tttttagcac ttgtgtatac acggctgtac tgctcttttt ctacgatttg gatcgcattt
     2941 tctactaaat cccgaaccat tgattctaca tctcttccga cataaccgac ttcagtaaat
     3001 tttgttgctt cgactttgac aaatggtgca ttgacgattt ttgccaaacg tcgtgcgatt
     3061 tctgttttac cgacccctgt aggtccgatc atcagcatat tttttggtgt aatatcttgt
     3121 tgcatttttt catctaactg caaacggcga tagcggttac gcaaagcaac ggcaacagat
     3181 ttttttgctg cgtgctgtcc tacgatatat tcatctaatt cacttacgat ttgtcttggt
     3241 gtttgtttta attcatacat atctactcac ctcttacagt tcttctacga taatattatg
     3301 attagtaaag atacagatat ctgcggcaat atttaacgca ttttctgcaa tttctttcgc
     3361 actcatgtcg ttttgagcat agtttttcat tgctcgggct gcagccaacg caaaattccc
     3421 tcctgatccg atagctaaga taccatcatc tggtgtgata acttctcctg tacctgaaac
     3481 aagaagcatt tctttatcat tcattacgat cagcatcgct tcaagttttt gcatagattg
     3541 ctgtgtccgc cattcttgag ctaattcgac agctgcgcgt tgtagattcc cgttatattc
     3601 gtttagtttg ccttcaaatt tttcttctaa agtaaacgca tctgcaacac ttccggcgaa
     3661 acctacaaca acttctccat tgtagatacg tcgtactttc tttgcagtgc ctttcatgac
     3721 aacagattca cccattgtta cttggccatc tccagccata gcaaatttcc cgtctttttc
     3781 gacggcacag atagtggttg aatgaaatgg tgattcgacc atgtttgttt cctcctaaat
     3841 ttgttctttt ccttattttt acgctcttgg atggaaagaa cgatagtttt tttgtaaact
     3901 ttcttttgtt acatgggcat agatctgggt agtcgataaa ttggcatgtc ctagcaattc
     3961 ttggactgtc cgcaaatctg ccccattatt taataaatga gtagcaaatg tatggcgcag
     4021 catgtgagga tggatatcac tatccaaact gctttttttg atcatttgat tcaagacata
     4081 ttcaattcca gtaggcgtga ttggttttcc atgatgattc acaaaaacga tatcatgctc
     4141 ttcgtgatat tttgtcatca atacctggcg gccttccctg aaatattctt gcagagcatc
     4201 ttgagcaaaa gaacctagag gagcatatct ctctttgttc cctttaccat ggatcaacat
     4261 gacctctgaa tcaaaatcaa tgtctgatac cgacaaactg ctacactcac ttaaacggat
     4321 gcctgacccg taaaggactt ccagtaaagc gcggttcctc aaatccaaag gactatctcc
     4381 tgctacgctg tcaaaaagtg cttgcatttc attttcataa aaaaaacgtg gcagtctcaa
     4441 atttttcttt ttgagatgaa cgtaagaaaa tggattttct tttatcactt cttctttgag
     4501 aagatactga taaaacgaac gtaggctggc tatcttgcga ctgatagaat ttctgctata
     4561 gctaggacga tgatcagcta atgcactcaa atagacacga accgtaaaat attccgcctt
     4621 cagcagatca gcgtctccag attcctccaa aaaatgtttg aaatggagaa tgtcttcttc
     4681 atatgcttct ttcgtttttt ctgaatatcc tctttcgaca atcaaataac gcaaaaattt
     4741 ttgttcccac gtggcttctg tcattttctc accttccttt tgtcccagag aataatttag
     4801 cacagcgttt ataaaaagac aaataaattg tcagaattta accaatattt ctaagtttgt
     4861 tcacaattgg cgcaattcct cacattttgt ttgagaaatt cttaagaaaa acgcaagaaa
     4921 aagagcgaga ctatccgtct caccctcttc atggagtttc cttactcatt tgggattgca
     4981 gttttttcta attctgtttt tattgcctca ttagctttta aagctcgttg tgcaattgct
     5041 tcatatcttg cttttttgtc tcgaatgcgc tctggcagtt caggaaacag accatagttg
     5101 gcattcatcg gttggaaatg ttttccttcc gcatgagtaa tgtagtaagc catacttcca
     5161 atagctgttt cttgtggaaa ctcgactggt tccatttctt ttgctaagcg tgcggcgttg
     5221 attccagcaa gtagtccgct cgctgcactt tcaacatagc cttctacacc agtcatctga
     5281 cctgcaaaga acagatcttc gcgtttcgtt gattggtaag tcggtttcag caattctggc
     5341 gaattcataa agctgtttcg gtgcatcaca ccatagcgaa cgaattcagc attttctaac
     5401 ccaggaatca tccggaaaac acgtttttgc tcgccccatt tcaagtgagt ctgaaagccc
     5461 acgatgttgt ataaagaagc tgcagcattg tcttgacgca gctggataac agcataagga
     5521 cgtttgccag ttttaggatc ttccaatcca actggtttca taggtccgaa aagcatcgtt
     5581 ttgaatcctc gctgtgccat tacttcaatt ggcatacatc cttcaaaata tttttctttc
     5641 tcaaaagatt taagttctgc cacttcggca ttgattagtg cctcatggaa agctttgaat
     5701 tcctcttctg tcatcggaca gttcaagtaa gctgcttctc ctttgtcata gcgggacttc
     5761 aaatatactt tatccatatc gatcgtagct ttgtctacga ttggtgcagc tgcatcatag
     5821 aaataaaaac catctgaacc attgaatgct ttgatgcttt ctgctaatgg atgagaagtc
     5881 aaaggtcctg ttgctactac ggtgattcct tccggtattt cagtaatttc ttcgtttatc
     5941 actgttacta atggatgctc tttgactttt cgggtaattg tttcagaaaa agaatcgcgg
     6001 tcaacagcta aggcaccacc agctggcact gctgtttcat ctgccgaagt gattactacc
     6061 gaattcaatc ggcgcatttc ttctttcaat aaccctactg cattagccaa actgtttcct
     6121 cttaatgaat tggaacatac tagttcagca aaattacttg tgtgatgcgc ctcagtcgat
     6181 ttgactggac gcatttcata taaacggaca gggactcctg cttgtgcgat ctgccaagca
     6241 gcttcacttc cggcaagccc tgctccaaca acatttacca ttttcaatga aagaacctct
     6301 tttctattat ttttggatgt cttcttcgta atctccattt acacagacta cttgtttacc
     6361 gcctttgact ttcttctcga ccagatatcc gtcacatttt ggacaatttc tgcccactgg
     6421 tttatcccaa gaagtgaatt cacattctgg gaaacgggaa caaccataga atagtctgtt
     6481 tttcttagat tttcgttcaa tgacttgtcc ttcatgacat actgggcaag tcacaccgat
     6541 ttcttttacg attggtttcg tattccgaca atcaggaaaa ttactgcaag cataaaactt
     6601 cccatatttc cctaatttta tcaccatcgg atgtccacag acatcacaat cgaatcctgc
     6661 tggttcatct ttgatttgaa ttttttcgat tttttcttcc gcattcgtca gttctttttc
     6721 aaacggttta tagaaacgat caaccacttt gacccacgct tccgtgcctt cttcaatttt
     6781 atccaaatct ccttccattt ctgctgtgaa atggatatcg acgatttgag ggaagaattc
     6841 acagattaat gaattgacaa tttctcctag ttcagtcggc tcaaatcttt tttgtgtcaa
     6901 ttttacatag tagcgtcttt ggatcgtatc aagtgttggt gcataagtgg aaggtcgccc
     6961 taccccgttt tcttctagtg cacgaatcaa cgtagcctca ctaaaacgtg ctggtggttg
     7021 agtaaaatgt tgttttggtt caatatcaac agattggact acatcgcctt cttcaagttc
     7081 tggaagaata ttttctttct cttctttgcc gtcatctcta ccttccacat acacttgcat
     7141 gaatcctttg aatttgattt ttgaaccgtt cgcaatgaag atgacaccat tttgttctaa
     7201 tgtcactttc attgtatcta aaatagctgg tgtcatctga ctagccacaa aacgtgacca
     7261 gatcaatgta taaagtttca attgatcttt atctaaatat tgtttgagtt catctggtgt
     7321 acgaagcaca ctcgttggac gcacagcttc atgggcatct tgtgcgcctt gagcattttt
     7381 gatctttcgg tgatcatgtc tagaaaattc ttttccatac gtatcttcaa taaatgctgc
     7441 ggcctctgct tttgctgtat cggcaatccg ggtagaatca gtacgcatgt atgtaatcaa
     7501 gccgactgtt ccttgtttac ccaaagtgat tccttcatat aattgctgtg ctaccatcat
     7561 ggtttttctt gttcgaaagt ttaacttacg ggcagcttct tgttgcaggc tacttgtagt
     7621 gaaaggattc gcagggtttc ttttgcgctc tttcttttct acttttttaa cttcgaagtc
     7681 tgttccatca attctagcag tgacttcttt tacactttgt gcatctggta atttcttttt
     7741 cttaccgtcg attccccaga aatttgcttt gaatttcttg cgagcttttt taaaattacc
     7801 gtcgatgctc caatattctt ctggaacaaa ttctcggatc tctttttcac ggtcaataat
     7861 aatttttaaa gcgacagatt ggacacgtcc tgcacttaac cctttcttga ccttacgcca
     7921 gagaatagga ctgatcgaat aaccaacgat tctgtctaag gtacgacgag cttgctgtgc
     7981 atctactaaa tctacatcga tcgttcttgg ttccttaaaa gctgctttga ctgcgtcttt
     8041 tgtgatttca ttgaagacca cccgattttt ttctttcaga tccaacccaa gtaggtacgc
     8101 taaatgccaa gcaatcgctt ctccttctct atccgggtca cttgccaagt aaactttttg
     8161 agcttttttt gctgcggctt tcaggctttt gatgacatcg ccttttccgc gtatagaaat
     8221 ataatggggt tcataattgt tttcaaaatc gatacccatt ttacttttcg gtaaatctct
     8281 tatatggcca acactggcca ttactttata gtttcgtcca agatatttct caattgtctt
     8341 ggcttttgca ggtgattcta caatcactaa atatttatac gccattactg aatggactcc
     8401 tttccattgt cgtgttccta ctattaaaag aggattcata caaatcgtag ctaatcatat
     8461 ccattcagaa aacgtttgtc aagaaaagca aatgaaaagt atggtgttat tctttaaatt
     8521 ctgccaagat atcttcaccc gaaaccgtgc aaactgcacc gttttggatc aaatgatgac
     8581 atccggtaga atgttctgtt aaaatatttc ctggaacaga aaaaactgtt cttccaagat
     8641 ccaatgcttg ctgtgctgtt atcagagagc cgcttttttt cttggcttca aagacacatg
     8701 ttcctttaga caaagctgcg ataatccgat ttctcattgg aaaacaatgc tttttcgggc
     8761 cggattgagg aggatattca ctcaaaagaa gatgatcatt tgcaatcacc tcttgcaagt
     8821 cacgattttc agcaggatag acttgctcta tccctgttcc aatgactgcg attgtccgtc
     8881 caccatgaga gattgctgct tggtgaccgt atgtatctat ccctttcgcg cagccactga
     8941 cgatcacata tccagcttct atcactggtt ttagtaaata ataaactgtt tttttggcta
     9001 aagcagaagt gtgtcttcca ccaacaacgc ttaacatgtt acaagaaagt aaagatagat
     9061 caccattata aaacagtaca attggcggat aggtcaagtg aagcagctga gggggatatt
     9121 tgggatcaaa gcaagtgata aacgactgtt tcgattggat tttgccccag ttagcgtgaa
     9181 tttcctgcca acttttgcga aacagctccc ggtgtttggt tattttacct atcttaatga
     9241 tgtcttcaaa tccgatttct ttataaggat actgcatcat ccagttagca agtgcccatt
     9301 ttccttgact actgattcct tttgtataag caagtttcaa taaattttct tctatttgat
     9361 acatcataaa accgcctttc gtctctcttt ctaataagat acgtaaaagc ggctgttttt
     9421 tattgtaaat atttttttac aggtgcaaaa cttttacgat ggattggcgt aattccttgt
     9481 cgttcaagtc cttctaagtg ttcctttgtt ccataacctg cattatgcga gaaaccatat
     9541 ccaggataaa gcacgtcata ttctttcatc aattggtctc gatatacttt agcaatgata
     9601 cttgcagcag caatcgacac agatcgtgca tcccctttga ttattttttc ctgctgaata
     9661 ggcaaatcca aggtcatcgc atcgatcaac aaatagcttg gtacaatgga caatttttct
     9721 actgcttgga tcatcgctaa tttacttgct tcataaatat tcacatcatc gattgtctgc
     9781 tgatcaacga tcccgatccc gattgccagg gctttttctt gaacttgttg ataaagaagt
     9841 tctcgctttt tctctgataa ttgtttggag tcattcagcc ctaatatgat ctcatttttc
     9901 ggcaagataa ctgcagctgc cacgacaggt ccagctaatg gtcctcttcc tacttcatca
     9961 atgccggcaa tccattggtg accttgtgcg tacccttgct tttcaaagca aaacatttct
    10021 tcatattttt ccttaattaa tgcttccttt ttcaatcgtc gttcaaaaga agccagtgct
    10081 tgctgcacgc ctttgcgtgg atcatttctt aatgattcta gtgtaggatc atctattctc
    10141 tgtatgcttt tcaatcgttc tttgatactt tggatggatt cagtcatcac ttttttgctc
    10201 catttcttcg caacgatcca gtgtgtatcg tccaagtttt ccttgacgaa tatcatgcac
    10261 gactaattcg ctgccacgat catagtcttc tttataccca cgttttgctg taatatccat
    10321 cagtaattcc ggtgccaatt tttcttcttg ctcgattgat aaaccataac gatcgctgat
    10381 tcttcctgaa taatatcggg caaaaaagtc taatccgtaa atcgctaaat catctaaatg
    10441 gacaagctgg tctttgatcg cgcctgtcag cgctagtttt ttgccgattt cttcatcttc
    10501 aaatttgggc cataaaatcc ctggtgtgtc taacaattcc aactcattac ctaaacgaag
    10561 ccactgctga ccttttgtta cgccaggctt atttcctgtc tgtgcaattt tcttgcctac
    10621 tagtcgattc atcaacgtag atttcccaac atttggaata cctaagacca ttgcccgaat
    10681 agcgcgaggc ttgatccccc gagcagcatc tcttgcccgt ttttctttca atgcttcttt
    10741 agccgcaggt actagacctt taattccttt actttcttgt gccgtgatag ctaatgcaag
    10801 atggccttgt ttacgaaaat attcttgcca cagctttgtc tgttgtggat ctgccagatc
    10861 cgctttattc aataaaacaa ggcgaggttt ttgctgaatg atctgatcta gcattggatt
    10921 acgagaagat aaaggtaatc gtgcgtctac caattcaaat acgatgtcca catatttcat
    10981 tttttcagaa acttctcgtc gggcttttgc catatgtccc ggaaaccatt ggatggtcat
    11041 tgttctctcc attcctttca taccggaata ttccccggct ttacttgttt ttttcttttt
    11101 caatataaat tcactttttt attataaaga aattccatct attagttaag tgaaagtgaa
    11161 ccagtcctca ttctatcaca tcttcacttt tttgatgatg caaattttta ttttggtttc
    11221 tatatatgaa tctaaatttt tgacagcgtt tcctaaataa gagatgatag acgaacaaaa
    11281 cagaaaggag acgaaacaaa tgaatagtat ggtttttgtt aattttcctg ttgctgatgt
    11341 caatcgttcc gttgcttttt atgaaaagct gggttttaaa aaaaatgaag aattttctac
    11401 tgaagaagct ggttcaatgg tatgggatga cactttttgg ataatgcttc tctctcatga
    11461 tttttataaa aaatttataa aagataaaga aatagctgat aataaaaaaa caagtggtgc
    11521 tttgatttcg tttagtgttg aaaatgcgga tgaagtaaaa aaatttgctc aaattgcaaa
    11581 agaaaatggt ggtactttcc acgaagtaga tatgggaatg cctgaagaag aaatgttttc
    11641 attagaagtc caagatctag acggaaatac attagaaccc gtatggatga agatgtaagc
    11701 agataactaa tctgacgttt tttataacaa aaaaacaaag gcggatgata cgataagtat
    11761 tctccgcctc tatttttttt attcgtacaa tctctttttt acagtttata aaagcagtct
    11821 tctcaccctt tttttaattg ttagatgcca gtgtatgtaa atcaccaatg tgtcatgaca
    11881 cattggtgat t
//
LOCUS       DACBZK010000078        11623 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.081, whole genome shotgun sequence.
ACCESSION   DACBZK010000078 DACBZK010000000
VERSION     DACBZK010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11623
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.081"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(286..2070)
                     /locus_tag="IVD66_002291"
     CDS             complement(286..2070)
                     /locus_tag="IVD66_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6146483.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFLAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            complement(2070..3821)
                     /locus_tag="IVD66_002292"
     CDS             complement(2070..3821)
                     /locus_tag="IVD66_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6146484.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            complement(3963..4187)
                     /locus_tag="IVD66_002293"
     CDS             complement(3963..4187)
                     /locus_tag="IVD66_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HAP6146485.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            4438..6024
                     /locus_tag="IVD66_002294"
     CDS             4438..6024
                     /locus_tag="IVD66_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HAP6146486.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVSQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            complement(6090..7865)
                     /locus_tag="IVD66_002295"
     CDS             complement(6090..7865)
                     /locus_tag="IVD66_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HAP6146487.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(8078..8980)
                     /locus_tag="IVD66_002296"
     CDS             complement(8078..8980)
                     /locus_tag="IVD66_002296"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HAP6146488.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAEKGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQTFDPEVFPELLAEEVIL"
     gene            9259..11604
                     /locus_tag="IVD66_002297"
     CDS             9259..11604
                     /locus_tag="IVD66_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAP6146489.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
BASE COUNT         3545 a         2361 c         2141 g         3576 t
ORIGIN      
        1 caaaaagaaa aacccaaaaa gccgtccatg aaaccatggg agactcatca ggtttagctt
       61 gcatcaggca atcactatcc aagttgtatc gttttcttta tattatcgaa agcaaatgct
      121 tttgtcaacg ctttcttagt ggctattagg cacttctgac tagctgtcga atcttttttt
      181 aaatctggtg actacgacac taactctcac agatgaaaaa tatgagaagc tatgttttat
      241 tttcactcta gtgcttaggt caaaattcta ctgtcacaac atcttttata taccactgct
      301 ttgcagtttg tacatatctg catacaaacc attttgcgct agaagtgttt catgattccc
      361 gcgttctact atatgacctt tgtctaaaac taaaatcaat tctgcatctc gaatcgttga
      421 cagccgatgg gcaatcgcaa tcgttgtccg tccttgacgc atttttgcca atccttcttg
      481 gatcaatcct tctgtttcag tatcgatatt tgctgttgct tcatccaata ctagaatttt
      541 aggatcagtc acgattgttc gcgcaaaagt gatcagctgt cgttgtccac tagaatagct
      601 ggcaccatgt tcgatcactt ttgagtgata tccttttggt aattcatcga tgaatttgtt
      661 tgcttgaaca aactcagccg catggcgtat ctgttcgtct gtgatagctg gattcatcat
      721 ccgaatattt cctgcgatat ccccataaaa caagaaagca tcttgcaaga ccagccccat
      781 tttcttacgt aactcttcca ttggatattc tcgaatgtca tgatcatcaa tcaatatctg
      841 accttcataa aattcgtaaa accgcatcaa tacgttgatg atcgagcttt ttccgcttcc
      901 ggtgtgtccc actaatgcaa cggtctctcc cggattagca acaaaagaga tattgtttaa
      961 tacattgtgc tctccatcat aagaaaagct tacattgcga aactcaatct tacctgaagt
     1021 aatcatttga tctgctccag ggttttgttg tggtgcatat tcttccgtat ccataatctt
     1081 caagatacga ctaccagcaa ccatcccatc tgtgaagatg ctcaaaaagt ccatcatttg
     1141 agacattgga ttaaaaaatc cctggacata ggtcgtaaat gcatagatca gtccaacttc
     1201 tacgggagaa tgcaacgcat cgatcccaaa caaagtcaac accaacgcaa tcgccaatgc
     1261 atatagaaaa ttgatgatcg gacttaacag aatcgaattc gttttgatca tcgcataacg
     1321 cgtgtctaaa tactcattgt tcacttgttc aaattcttta gctaaacgag cttcttggcg
     1381 aaactgctgg ataatacgca tgccggaaat cgattcattc aatttcgtgt tcagctgact
     1441 taatttttcc cgcatatttc ggtaaatacg agaactgaat ttctggtaat accagatgac
     1501 gattcctaaa atcggcaaaa acaccaaagt ccacaaggca atttctccat tgatttgaaa
     1561 catggcaagg aatgaagaaa cgactgcaaa gatcccagtc aataccatca aaaagacgta
     1621 ccaaaattca aatagcgttt ctgtgtcatt cgtcactcga gaaacggttg atcctgccgg
     1681 tgtctgatca aaataacgca tacctagtgt atgcagcttt tcaaataatt ttaccctaat
     1741 atactgatag gtcttcaatg aggccatgga atacaaatac cattggaaaa accaaatgat
     1801 actttttact atgactccaa ataagtacat accagcaaaa aacaaaataa cttgtgtcgt
     1861 agccgactgt ttagccagat gatcatccat aaaagtttgg atgatccttg gcaataggac
     1921 attgatcaca gacaaagcaa acgcaaataa gatagcaacg atgaacgttc ttctaaaagg
     1981 tttggcgaac ttcatcagtc gtttgatgat ctttttctgt tctttaagtg gaatcgattt
     2041 tgtccattcc gattgataat tttcatccat caggcctcgc ctccttctat cttcgcttct
     2101 aattgctgtt tctcccacat ttgttcatac cagccgccta gtgcaagcag ctcatgatgg
     2161 gttcctcgtt caatgatttt cccttgatcg acaacaatga tttcttttgc atgcatcacg
     2221 ctacttaaac ggtgagctgc aatgatagtt gttttctctt ttcttatttc ttttaaatta
     2281 tgcaagatag cttcttctgt tttggcatct actgcagaga gtgcatcatc taatattaat
     2341 aattcaggat ttttgatcaa tgctcgagca atcgaaatcc tttgtttctg tccgccagat
     2401 aaagagactc cacgttctcc aactaaggta tcataacctt ttggtaattc cttgatttca
     2461 ttgttgataa atgctaaaga agccgcatgc tctacttctt cttctgaaag ttttggatta
     2521 gaaaaacgga tattatctcg aatggtcatc gaaaacaaga agtgatcctg aggcacatag
     2581 ccgattgatc ctaataaagc attcaatgaa tattctttga tcgaacgtcc gccaaattgg
     2641 attttccctt gataatcatc gtattcacgc atcagtaatt tgatgatcgt cgtttttccc
     2701 gcaccagttt tcccaacaat acctaatgtt tctccttctt ggatcgcaaa cttgatttgt
     2761 tctaatgctg gtgattcttc tttcggataa ttaaaagagg aaatagctac attcagctcg
     2821 ccttttgccg gggtctgcac tgcacccagt tgttccacga tatgcgtctt ttcatgcaaa
     2881 agttcattga cgcgatcata agaagcattt cctctttcca atacgttgaa caatcgacca
     2941 atcgcaaaca tcggccaaac aagcataccg atataactaa taaatgagac catctgcccg
     3001 atcgagatcg tgccttccaa gacatacttt ccacctaaaa taattgttgc aacataagac
     3061 agaccgataa tcaaggtaat gaatggatca aataaggagt ctaaaaaatt gactcgtttg
     3121 tttttaataa ttgcatcttc aatcttttct tcaaaatccg ctagatcttc tttttcttgt
     3181 ccaaatgttt taatgacttt gatcccagtg atactttctt gtgtcttatc attgatacta
     3241 gaaaaagctt cttgcgaatc acgaaaagca tcatggagtt ttgaccccag cactcgtgaa
     3301 gtgacggcca gcaaaggcag aggaatcagc gcaatcagtg ttaagcgcca atcaataaac
     3361 aaaatcatcg caatgatcgt tgttccgccc gtaatcactg aatctgcaaa ggtcaagata
     3421 ccagctcctg ctacattctg gatcgcattc aaatcattcg ttgcgtgagc catcaaatcc
     3481 ccagtccgat atttttggta aaagagattg tccatttctg taaaatgttt gaataactgc
     3541 tgccgaagtt ctttctccaa tcgagctgca cttccccaaa tattcgtccg ccagatataa
     3601 cgaaaaagat attgtaaaaa agcagcgata atcaatagga agatccaccc gaaaatgatc
     3661 tttattgata aatttttatc ggcgatctca tcaatgatga tcccaatcac ttttggagga
     3721 actaactgta ccaaggccac tgcgaatagc gagaaaaccc caattaaata atgtttcttt
     3781 tcctgacgaa aaaaccagcc taattttcta aaaatcgaca ttttactcct cctttgtctt
     3841 tatcaagagc ctaggattgt ctgtgcttgt cttttttgct gaataatctg aatagtctaa
     3901 caaattacga aataaaaaac ggactgaaaa aatcagcccg taaaaagtcg ttgggtcaga
     3961 acctattttt tcccttggtt cttcatttgc tgcatcatct ggcgaatttt cttctcagat
     4021 ggtttttgcc ccattgacat catcattgat cgcaacatgt cctcattaac gggaggattt
     4081 ttttctaaat agtctttcat atatttacgc gctaggaaaa agccacctac tgcgccgatt
     4141 agcaaagcaa taatagcaat aagtacgaca atacctgttg ataacatata aatctctcct
     4201 ttctatttcc gaattgctct caatgactta ttttactaaa gtttattgaa aaaagaaagg
     4261 cgtattcttt agtttcatgc aaaaaatagt ggttttttta gaggagaaca aaatttcttt
     4321 cgtcatctag caagacgcgc catgaaaaaa aattaggcgt accgaatctt tttctttaat
     4381 tttttctttt tgaggtgtag aatgtaatcg tagataaata ggaaaggtgg ttttttcttg
     4441 aataatcaat ccaataaaca atttcataag catcgactta ttgaacatac aaatggttta
     4501 tctttagctg aagtaaatgg aacagttgat gtaccaaagg ggaaaagttt ttttaaaaca
     4561 cttcttgctt actctggacc tggtgcgtta gtagcagttg ggtatatgga cccgggtaac
     4621 tggtctactt cgatcaccgg aggacaaaat ttccaatatt tattgatgtc agttattttg
     4681 atgtctagtc tgattgctat gcttttacag tatatggcag caaaattagg aatcgtgagc
     4741 caaatggatt tggcacaggc aatccgagca cgcacaagta agacattagg tgtcatttta
     4801 tggatcttga ctgaattagc cattatggca acagatattg cagaagtcat tggtgcagca
     4861 atcgccctct acttactttt tgatattcca ttggtgattg ccgtctttat tactgtatta
     4921 gatgttttcg ttctcttact actgacaaaa gtcgggtttc gtaagatcga agcactggtt
     4981 gtctgcttaa ttttcgtcat tttattcgtt tttgtctatc aagttggctt gtctaaccca
     5041 gattggcaca gtttatttgc tggctttatc cctaacagtc atacattctc agactcaccg
     5101 gtcatcggcg gcgaaactcc gctgactgga gctttaggga ttattggtgc aacagtcatg
     5161 ccgcataact tatatcttca ttcagcagtt tcacaaactc ggaagatcga tcaccaaaac
     5221 gaagaagatg tagcacaagc tgtacgtttt tctacttggg attctaatat ccagttgtca
     5281 atggcttttc tagtcaatgc actgctattg atcatgggtg tcgctgtctt caaaaccggt
     5341 tctgtccaag atccttcctt ttttggtctg tatgaagctt tatctgatcc atcagctatg
     5401 agcaatggta ttttgattgc tgtagcaaaa tctggtatct tgtccacttt atttgctgta
     5461 gcacttcttg cttctggcca gaactctact attactggta cgttgaccgg tcaagtcatc
     5521 atggaaggat tcatccatat gcgtatcccg atttggctaa gaagactggt cacacgattg
     5581 ctttctgtga ttcctgtatt gatttgtgtt ttgtttacaa gtacaaaagg aacgatcgaa
     5641 gaacatgccg ctttgaataa cttaatgaat gaatcccagg tgttcttggc ttttgcgttg
     5701 ccgttttcga tgattccttt actgatgatg accaacagcc aagcggagat gggtagccga
     5761 tttaaaaatt cattcatcgt aaaacttctt ggctggttct ctgtgattag tctaacttac
     5821 ttgaacttac gaggattacc aggacagatc gaaagtttct tcggcgagca agccacttcc
     5881 gctcaactag cattggctga tcacatcgct tatgtaatca ttgttcttgt ccttctcctg
     5941 ttggcatgga cgattggtga tttatataaa ggaaacaaaa aatatgaaca gcttttgcag
     6001 gaaacggtag aagaaatcga ataaaaactg atttttccac acaaagaccc ttgatagtta
     6061 ggttaaaaat ctagctacca agggtctttt tatttagaag ataaagcttt tttcagattt
     6121 aatttactga aaactagcat gcttgttact acgatgaatt gcgttaatgg cacgcctgca
     6181 ccagtgtaga cacttaaaaa atagtccttt ttttctggcg cataagaaca aaaccatgag
     6241 acaccgaaaa gaaaaaccaa ttgtgtcagt attaatccgg tgaccacaat caaagaggaa
     6301 ctataatagg cacgatcagc ttttgcaaat acggttccta gtatcataag taatatccct
     6361 gctattgaag caatcagcac gggaatagcc agaacttggt aaatttttat gatgacattc
     6421 gcgacttttg ctgattttgt taattggaaa ttaggtgttc tcggttcatt actatcgatc
     6481 caattctcca ttagcggaag gtttaataat tcttgagcct gtttgacttg ttcttgcgtt
     6541 ccgaaactat aatttcctcc ttgatggaaa tctttatatc gccatgcata agcgtatcct
     6601 gattgaagga aatcgaatac gattggcaga tcactcatcg tctttccatc tcctgatccc
     6661 atcagataga actctttttt ctttttgatt gttcccttgt gataggcttc ttctaattct
     6721 tggttgactt ttttccaaaa atcattggtt tcttttgcat tgttttggta ataaccagat
     6781 tcgcttacca catctcgcaa tgcccaaaag atgatatctc cgggtaattc ttttactttt
     6841 ccaccttgag tccacgcgtg agtcgtatat aattcgtcaa tacgggtaga aacagtatgg
     6901 aatgtaggag atgcggctaa tgctttattt agtgcagcat gtgagaccca tatctcactg
     6961 ttttctttat tcaagttcgt ttcatcatct attcggatca gttgtttcat caaacgtcca
     7021 aattctccac tggaacggtc attgatggtt gcaataccgt atgttgtctc atttttatat
     7081 tcgatccatt gatagacgat ggaaaagcca actataggaa gtaaaaacaa tgaaagtttc
     7141 agccattccc gtttcgagag aagaaagagt cgttttttta acttctttac ttctttgaaa
     7201 gaaaagtctt gccctagcaa gatctggacg aaactgatac ccaaagctac tacagtaaaa
     7261 ggaagaagcc agatagaatc ttcgcgaatg aaccaaaaga aaggaaaagc gacagaaagc
     7321 cctaaaaacc atggcagcaa ttttctgcta gaaccgtatt tgcggtaata aatagctaat
     7381 aaacaagcga taatgatctc aacagccgga atcacgaggg cattacgata tgttcgagtg
     7441 gaatattcat gtgtaaaact aatcggagaa aacaaaaaat aaaaatagat acttaaaaga
     7501 agatacttgt tcttcacaat cggtttaaac gcgagtgcaa ccaatatact ggcaaaaata
     7561 ctgaacatgc cgaacaaaac tgcataagaa agatgcagtt tatgtgcaag tactaaaaat
     7621 aagctgtagg agattccttt ggaaagtgtt gtagtcgtat actcccctag ccatttaccg
     7681 tccaaaatat tttgagcata gcgaatcagc agctggtcat cataggttgc cgacatgtct
     7741 gttccataga ttgctttact atataaatac aaacgaataa ttgtaaataa tagggctatg
     7801 ccaagaataa agtatgtatg tttctttttt agttggttga tcaagggttt taaagtgttc
     7861 agcatctttt cgtccttcca atcacgtttt gccacttgct tgtgaaactt ttcgtttttt
     7921 tacttttcta ccagtatacc ttgtttgtct aaatttaaaa agagggggga gaagatgcat
     7981 gatgaaaaag actgcaaaaa gtactccttt gtttcttaaa caaaaaagga caaggcaatg
     8041 tgcctggtcc ttttttgctg ctgtcagata gaaaatctta gagtatcact tcttctgcta
     8101 ataactcagg aaacacttct ggatcgaatg tttgcgcttt gaacatggcg atttcttttc
     8161 catatggtgc gtaagctttc tttttatctt tgcctacata gggagtttcc aagattttcg
     8221 aaatattgtc aaacattgga tcatggacga tcttattcag cgtgtcgaat ccgattgttc
     8281 caaaaccaat attggcgtgc cggtctttat gcgaaccttg cggattttta gaatcattga
     8341 tatggagtac tttaagccga tctaacccga tgatcttatc aaactcttcc attacacctg
     8401 aaaagtcttc tttaatatta taaccggcat cattcgtatg acaggtgtca aaagtaacgg
     8461 ataatttttc attcaatttt actccatcga tgatttgcgc taattcctca aatgttcgac
     8521 cgatttccgt acctttacct gccattgtct ccaaagcgat ttgtgccgtc tgttcttttg
     8581 tcaaaacttc attcaagcct tcaataattc tagcaattcc ggcttctgtt cctgccccta
     8641 catgagcacc tgggtgaagt gtaatttgag tagcgcctaa agcttccgca cgaacaatct
     8701 cttctctcag aaattggacg gcaaaaggaa acatttctgg tttgatcgta ttccccaaat
     8761 taatgatata aggggcatga acgacgatat ttgttagacc tttttctgcc atgtacgctt
     8821 ttccggcatc aatattcatc tcttcgatgg cttttcttct agtgttttga ggggcgcctg
     8881 tatagatcat aaaagtcgaa gatccataac tggctgcttc ttctgctgct cctaacagca
     8941 ttttctttcc gctcatgctg acgtgtgagc ctaataacat ggatggattc ctccttgaaa
     9001 ggcaattgtt actaacaatt cctatatatt ggtaagatga tatacaaaga aaatgattga
     9061 tttttctttg ccctgttctc catagtaact gaaattttct ctaaagaaaa gcttaagaac
     9121 tcttttataa taaagatcat tttctcacgt tttaactctt ttaaaaaaga aattcctgcc
     9181 aaaaacagcc ttgtctgttt ttttgttcta ttatttgcta taattagcga aataaaacca
     9241 ttagttgagg tgaccctttt gccacgcaaa aatactcgaa aaaaacagaa tagaagaaaa
     9301 aaagaaaaat ggtttgttcc taagattatt tttagagttt ttcaatcatt gactgttttt
     9361 attactgttc ttcttttgat gttcgcagct ctaggtattg gaataggcgc tggctatttt
     9421 gcctatctcg tcgaagacac acaattgccg actaaaaaag cactgcagac agaactagga
     9481 aacattacag aaacgtcaaa gattgtttat gcagataata cagagatatc aaaaatccag
     9541 acagatctga tgcgcacgac tatttcatct gataagattt cacctttatt gaaaactgca
     9601 attatcagca cagaggatga atacttcgat aaacaccaag gttacgttcc taaagctgtt
     9661 ttacgagcat tagtatctga agctactggt attggctctt ctggtggatc aactttgaca
     9721 cagcaattag tcaaacagca gatccttaca gatgaaacaa cattcaaacg taaagcaaac
     9781 gagatcattc tttctgcaca agtagaaaaa tacttttcaa aagatgagat cattgctacg
     9841 tatttgaatg tctcaccatt tggtcgtaat aataagggac aaaacattgc tggagtccag
     9901 gaagctgcaa aaggaatctt tggtgtagat gcaaaagatg tgacgctgcc gcaagctgct
     9961 tatatcgctg gattacccca aagcccgatc acgtatagtc catacacgaa cacaggcgcg
    10021 ctaaaagaag atctttctgc cggccttgcc agaaaagatt ttgttttatt cagtatgtat
    10081 cgtgaaggcc aaattacgaa agaacaatac gaagaagcaa aagcctatga ccttacaaaa
    10141 gactttctac cacaacaaat cgcagaacag actgacagag aattcttgta ttatactgtg
    10201 atgaatgaag caacaagaat cattgcacaa caattggctg aaaaagacaa cgctgatatg
    10261 tctgattcat cggtcagtga cgcttattat caaaaggcac agcaaacgat ccaaaataaa
    10321 ggatatacaa tccattcgac aatcgataaa gatgtctatg ctgcattgca aaatggcgtt
    10381 gaaaattatg gatacatgtt agatgatggt gctggcagtc aagtagaaac cggaaatgta
    10441 ttgatggata acagaactgg ccgcatctac ggattcgttg gcggacggaa ttacagtcag
    10501 aatcaaaata accatgcctt cgatacagaa cgtcaagctg gctcatcaat caaaccagtt
    10561 cttgtttatg gacctgcaat cgacatgggg cttatcggat cagaatcccg tgtatcagat
    10621 tatgcaacaa cttggcaaga aggagaaaat gctggcgaga aaatcgtcaa tgctactaac
    10681 gaaggatcga acaccttcca aaccgtccgt gagtcactag aatggtccaa caatatcccg
    10741 gcttatcact tatatcaaga tgtgttgaat tccggtggat cgaaacaata tgcttacgag
    10801 cactacttgg caaagatgaa ctacccggca aatgacaatt ggggcgttga atctgctcct
    10861 ttaggtacag tagatgtcac gacgcttcaa cagaccaacg gatttcaggc tttagcaaac
    10921 ggcggcgtct atgaagaagg ctatatcatc gattccatca cagataacgc aggaaatgta
    10981 atttataaac acgaaagcaa ctctgtccgg atctattcgg aagcaacggc atcgatcatg
    11041 aatgacatga tgcgtagtgt gatcaatgca aaaatcacta caccattcaa agatgccatc
    11101 tcaagcttaa acggaaatct aggaaaagca gattgggtcg gaaaaactgg ttctaccaat
    11161 gaataccgag attcatggct aattgtctct actccgtcta ttaccatcag tagctgggca
    11221 gggcacgatg acaatactgg aatggacagc aaagcaagga tacgttcggc taattatctt
    11281 gccaatctga tcaatcaagc ttaccaagca aaacctgaca tttttggcac tgatgagaaa
    11341 ttcgaattat catctgatgt gatgaagaaa aaagtatctg gatttactgg tcaaacacct
    11401 ggaaaagtta ctgtcaataa aaaatccatc caaacaccag gaaaaacagt tgaatcgcta
    11461 tgggcgaaaa atggaccgaa gaaaagcgcc tttaaatttg gcgttggcgg taccgatgaa
    11521 aactatacag attactggaa caccgcttca gcttatgcaa gagcgaatca agcaactaaa
    11581 gaatcagatg agaaagatga ttgatttaat agaatacaca gta
//
LOCUS       DACBZK010000079        11440 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.082, whole genome shotgun sequence.
ACCESSION   DACBZK010000079 DACBZK010000000
VERSION     DACBZK010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.082"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            184..1182
                     /locus_tag="IVD66_002298"
     CDS             184..1182
                     /locus_tag="IVD66_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP6146490.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1294..1803
                     /locus_tag="IVD66_002299"
     CDS             1294..1803
                     /locus_tag="IVD66_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HAP6146491.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1833..2492)
                     /locus_tag="IVD66_002300"
     CDS             complement(1833..2492)
                     /locus_tag="IVD66_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HAP6146492.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2494..3258)
                     /locus_tag="IVD66_002301"
     CDS             complement(2494..3258)
                     /locus_tag="IVD66_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HAP6146493.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3266..3943)
                     /locus_tag="IVD66_002302"
     CDS             complement(3266..3943)
                     /locus_tag="IVD66_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HAP6146494.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3980..5365)
                     /locus_tag="IVD66_002303"
     CDS             complement(3980..5365)
                     /locus_tag="IVD66_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAP6146495.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5575..5659)
                     /gene="ffs"
                     /locus_tag="IVD66_002304"
     ncRNA           complement(5575..5659)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="IVD66_002304"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="IVD66_002305"
     CDS             complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="IVD66_002305"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HAP6146496.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6304..7161
                     /locus_tag="IVD66_002306"
     CDS             6304..7161
                     /locus_tag="IVD66_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HAP6146497.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7242..7577)
                     /locus_tag="IVD66_002307"
     CDS             complement(7242..7577)
                     /locus_tag="IVD66_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146498.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7644..9014)
                     /locus_tag="IVD66_002308"
     CDS             complement(7644..9014)
                     /locus_tag="IVD66_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NOL1/NOP2/sun family putative RNA methylase"
                     /protein_id="HAP6146499.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9092..9628)
                     /locus_tag="IVD66_002309"
     CDS             complement(9092..9628)
                     /locus_tag="IVD66_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6146500.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9937..11418
                     /locus_tag="IVD66_002310"
     CDS             9937..11418
                     /locus_tag="IVD66_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP6146501.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         3515 a         2301 c         1854 g         3770 t
ORIGIN      
        1 tttgcatact tcataataat aataacataa tacctaacct ctcgtaaaaa tactagattt
       61 gttttctttt atttttcatc actagataca ttctataact taccgtttcg atttcgaatt
      121 caaacatttt tgagaagcat tctcaattaa attctgctat agtgtgaaaa gggaggaatt
      181 tttatggaaa tctatgacat tacaatcatc ggtgcaggtc ctgtagggat gtttgccgct
      241 ttttacgcag gaatgcgcca agctaaaaca aaaatcattg acagtctacc tcaacttggt
      301 ggtcaattag caactttgta tcccgaaaaa tatatttacg atattcctgg gtatccagca
      361 ataaaagcaa gtgaattaat cgatcaatta gaaaaacaat taactacttt taaccataca
      421 ttccatttaa aagaagaagt tctctcgctt actcgtgaag acgaagttat cgagattact
      481 acaaataaag gcatccatta ttccaaagca gtcattttag ctttaggaaa tggttcattc
      541 cagccaagaa aattgaattt agataatgct gaatcatttg aaaaccacgg attggattat
      601 ttcgtgaatg atttgatgaa gtatgctgga aaaaaagtcg ctattgctgg aggtggtgat
      661 tctgctatcg attggacgtt gatgttagag cctattgcaa gcgaagttta cttgattcat
      721 cgtcgcccgg aatttcgtgc gcacgaacat agtgtatcac gcttgaaatc ttcatctgtc
      781 aacttgctta ctccctatct catcgatgga ttatcaggca ataatgggga actgacagat
      841 atccggttaa aaaaagtgaa aagtgacgag acgattgatt tgatgattga ttctctgatc
      901 gtcaattatg gattctcttc taatttagaa catctttctt cttggggact tgatagtacc
      961 agaaatgcca ttactgtaaa atcagatatg tctacttcta ttccaggcgt ttatgcagct
     1021 ggtgacatct gtacctatga aggaaaagtg aaactgattg ctactgggct cggtgaagca
     1081 cctactgcag tgaacaacgc tttacactat attaatccaa aggaacgaac tcagcctggt
     1141 cacagcacaa gcttatacga taaaaatctt cgtcctagtt gattttttat atctctttgc
     1201 atttcaagtt aaacccgaaa gcagtttctt gcattttttt catgttccgt taacatgaaa
     1261 tagagaaaga aaaaataaag ggggagcaat aatatggtcg tcaaaactga gactttagaa
     1321 gaaaaggcaa gagaactatt gaaggaacgt ggcgtaactg tagaagatat cgcacaactt
     1381 gtcatgtttt tacaaaaaga ctatatttct gatttgactt tggcggattg tactgaaagt
     1441 gtcaacagcg tgctaacaaa gcgtgaagta cataacgcca ttatcactgg aatccaatta
     1501 gatatattag cagaaaagaa aaaattgatg agtccgttgc aacatattat cgaagatgac
     1561 gaaggccttt acggtatcga tgagatccta gccttgtcaa tcgtgaatgt ttacggtacg
     1621 atcggcttta cgaattatgg ttatatcgac aaggtgaaac ctggtatttt aaaagaacta
     1681 aacagccacg atggcgttca tgtccatacc ttcttagatg atatcgtcgg agcgatcgcc
     1741 gctgctgctg ccagtcgatt agcacacaaa gaaccagaaa aaagaagtcg ccttactcaa
     1801 taattcaaca aaaaaagaaa gaaaacgtct atttagacga gttctttctt ttttgtttgt
     1861 ttcaagctat tttttcctaa gaaaagaaaa acagcaaaaa ataattctaa taatacaaaa
     1921 aataagataa agctatgcat gaaaaattct tctggaagta cattgatgat tggatcagta
     1981 acgggatcga ataaccagtc atcgttgttg aaaaacgttt catgaaaaag gataaaaaag
     2041 cgatcaaatc ctatcatcat gaaaaaaccg aaaacaactg gcagtaacat gccgatttga
     2101 aacggacgaa tcaaccgcca aagccgatca ttcttttgca aatatttgat aaacaaaata
     2161 ctcgggatca aagtgatgaa aaacacagca taatccacta aaaacaaaat tttcacttca
     2221 taaaagtgat gggctccgct agcagaaact gggaaatctg gcaagctgag gatggttttg
     2281 aagggattat tgagataatt cattaggtga tcaaaatttt tcagtaacgt ctcttgatct
     2341 aaagaagtat aatccaaaat ttgcaaatgt ccgatatcaa atacgtatag tggtcgaaag
     2401 ttgatcgtca caccaactgc cagactgatc agtgtcagaa ataggctgaa caatccagca
     2461 tattccatcc actgccatct cgaatttttc atattagaag ctccattcat ccagtgattg
     2521 tttcacatag gtagctggga taggcaaccc aggtacatct tcttcttttg taaaacctga
     2581 taaaacgagc aaagtatcta tattattgcg tatcccagct tggatatctg tttcatagtt
     2641 atctccaacc atgattactt cttctttttg cagccctaat acttcaacgg ctttatccat
     2701 aatgatggct tctggttttc cgatgtagat cggcggcgtt tgggttgctg tctctacaaa
     2761 agagatgact gaccctgctc caggaagaag gccgcgttca gtaggtatat tcttatctgg
     2821 gttcgttcca atgaaagtag cacctttttg aatagcaagt gttgctttaa ctactttttc
     2881 ataggtcaga taattatcta agcctaccac tacatagtca ggagcctctt cttcccatgt
     2941 aaatccggca gctaaaatca agtcaatcaa tcctgcttct ccgataacat agactttttt
     3001 cccttttcca tctgctttca taaaatcgat tgttgccaaa gtagctgtgt agactgtctc
     3061 tggagctaca tgaatgtcaa actcatctgc tagacgatta gctactgttt ctggtgactt
     3121 agtcgtgtta ttggtaacaa acaagaaagg taattttctt ttttgcaatt cttccacaaa
     3181 tcgtttaccg gccggtatgg gttgtgtccc acgataaatc gttccgtcta aatcaattaa
     3241 atatccttta tagtccattc atccactact cttccctttt tctgatcgta aatgctgttt
     3301 ttgttttttc tacttgttta ggttgttctt gtttttttac tttttcagag gtttttgctg
     3361 actctgtttt tcgattttta ataaccggtt ttttgcgatt agatgcgact ggtccttttt
     3421 tctcatcgat atacgcacga ttatggtttt ttttcttttt tcggcgctga gttgtctttt
     3481 cttttttacc gccgattctc tcgatgacaa aatacgcaca accaaaattg caatattcgt
     3541 aaagatagtc ttccaaggaa tcgattcgct gatctggatg cgcccgtcga ttatccgctt
     3601 ggaaaaatcc ttttaggcgt agttgttcat aaccccaatc tcctacgata taatcatatc
     3661 gggctagtac atcactgtaa cgttctccaa gcttttctgc attaaatcct tcacgataat
     3721 cggacacaag ccgataatgt ctttcaccta tcaaaaaatt actgtcatct aacagtgtca
     3781 ctagctcgcc tttgactttt tctgctttag gctcctcaac gatttcttcc aaagcagctg
     3841 tcagttcttc ggtgactgtt gtttcctgtt cagctgatga ttttttctta gcaatttctg
     3901 ttttatgctc aacgttctgc tgttcatttt gttttgcaga catgcgttca ccacctatct
     3961 tttttattat accttgtttt tatttgattg ggtagtgagc tttcaagtaa tctcctacca
     4021 cacttcggat aaattcaggg aacaaaaatt cattttttcc agcaatctca atcgttggaa
     4081 aaaatggaac aaacatcaaa tgatctacgg tagtaaaagt ataattttta ttcagatcga
     4141 ttggcttgtt cttccaaaag acttgatggt taatagaatc atatgtgatt ccattataga
     4201 ccatctgccc aaaaatctta ccgcgaaatc ccattccctt cataggatag ttacgtaaaa
     4261 agttacgatt tttttctatt tctaaaacta agcggatcag atcatttcca cccaatgtga
     4321 catttaacaa gtgcatcgga tgcggcaacg cagtgtgaag ctgatcctga ttgacccgcc
     4381 cttttggaat ttcagttaaa aacagaccac tgtttaatat tgctgcttcc gtctttcctc
     4441 gttctttcac cgcctcaaag gctacttgga taaacgaatg ctcattgaag atatctagac
     4501 tcagagaaaa tggcaaatct gctacttctt tttcttttaa taattcatgc ccacgttcta
     4561 gataactatt tatttcttgt tcatcttctg taaaagctgt cattgtttcg gtagggatgg
     4621 ctttggctga atgcttaagg atttttttct cttcatcgat ggttaaatgg acttcaccga
     4681 catactgccc gtactttcca gcggctgcta tttggacatc attgattacg tgaccttctc
     4741 tgaataaatg atgggtgtgc gatcctaaaa taacatcaat tgctggtatt tcttttgcaa
     4801 tttggaaatc atcctgaatc ccgagatgac tcatcaaaac taaaacatcc acttgtgaac
     4861 gtaaatcttc gactaattct ggcaaaatat cataaggatt ccgtatgtcc cagccattcg
     4921 gattataagt aagcggaaat ggagcagtaa atgcaattag tccgattttc gtctggtgtt
     4981 tcgttgtaat gattttatat ggtttcgtcc atgccggtgg ctggagcgta tttttatcga
     5041 ataagttatc caggatgata tcaaactcag catgatcgta taaatgattc aactcttctt
     5101 tggaatttcc tacgccttca ttgtttccta tcgtcgctgc atcataacca acttcattca
     5161 tcagcaagat attttcctgt ccattcgttg cttctgacaa tggatgccaa cgatccacaa
     5221 aatcacctag atctactgca atcgttgtcg ttttttcttt cttttcgttt tctcgtttac
     5281 gttgatccaa aaaccttctg atccttggcc aattttctaa atgagaatgc agatcattcg
     5341 tatgtaaaat cactattttt tccatgtacc ctctcgcctc tctttatctt tatcatacca
     5401 taggcagctt tttcttccat tgaaacaagc tctatttcag agtttttcct gccttgaagc
     5461 aaattgtata agtacaatat tcgataaatc agtctggcta aaaaatcagg aacattcatt
     5521 tttacagtac tataaaaata aaaaaaacag acccgaaagt ctgttgtcgt ttcattataa
     5581 tcagacacat ggcggaacct gcttagtgct gcttccttcc agacctgaca cgcttcacaa
     5641 gcccaccatt gtcctagcct ttcggcaaag aatagtatac cttatttttc attcgttgac
     5701 cagtcttttt ttaatttctt ttttcgctgg cggagctttc ggaaaaagtc agtcaaaatc
     5761 atcccacatt cgtcttctaa aatgccacct tctacatatg cttggtggtt aaaccgctcg
     5821 tcctccaaaa gattcatcaa ggtaccggct gttccgcctt ttggatcata cgcgccgaaa
     5881 taaacttctg ctacacgaga caaaatcatc gcgccgctgc acataggaca aggctctaag
     5941 gtaacaaaaa gtgcagcatc ttccaagcgc cagcttccca ctttttcaca ggcttccttg
     6001 attgcaagca tttctgcatg tgtagtagca tcttgcgtgg tttctctaag gttatatcct
     6061 cttccaatca cttttccatc caatacaacc actgctccaa tcggaacttc atgaagcatt
     6121 tctgctttct ttgcttctgc caatgcaagg cgcatccatt tttctttttc tactgcatca
     6181 agatttgtat ttaccaatta cccttccctg cctttgtttt ttcttgtttt actttagcat
     6241 atgataaaaa ggctgtaact aacttttttt tctatggtaa aataaataca agaggtgaac
     6301 aagatgaaaa tggataaatt acttgctctt tacccacaag cacagaaaaa aaactctcca
     6361 gcatcagaag cggatatcct ttcttttgca attgatgatg cttttatctg gatcaaacaa
     6421 gattcattat ctcaacaaga aaccagcctt ttgaaagcgt tattccctgt aatcaacgat
     6481 caaaaaaaac acccatggta tcgctatctt tttaaagatg cttcttgtgt tcaagaaaaa
     6541 agctttcgtt tgatccagct tcacgtcgaa tcaaaaggag aattcttaaa aaaagaatgg
     6601 caagatacta ttttggaatt atttcgctat tctgctgatt tcttttttta tacagacaca
     6661 gatgcgctct tagtcgaaca aataaaccgt gattatcttg atgctactga aatcaacggt
     6721 atttttctat ctttagatgc tgattttgat acgacaacgt ctgtattcgt tggttctttc
     6781 cattcacctg gcaccgacct cgtccctttg tttgctgaag aaagaaaaat ttttttaaca
     6841 gagcaaaaca atctttatac tcacagccgt actttttcta tgcaagatgt ggctttacat
     6901 tactatacaa aagatactgt aaaagatagt aagttgatca aaagttacat agaactgatc
     6961 aaacaaaatg aaatggaagt gatcattcaa gaattatgga atgaattagg caatgtcagc
     7021 tctgctgcaa aaacactgtt tcttcatcgt aatactctaa aatatcgaat cgaaaaattt
     7081 caagaacagt ctggtttcaa tctaaaaaaa gccaacgatt tactgttttg ctatctttta
     7141 ttgcttcatg aacataatta aagatagatt aaaggggttg tgacaataat tttgtcacaa
     7201 ccccttattt cgaatgaata gtgttcaaaa gctagtttct cttacatcat tttttcaaca
     7261 aaatgcatta gccggtcttt tacatcttcg gttgaatctt tgattgaatc accataaaca
     7321 gagattttct tttttcctga tttgattttt gctaacattc ccatcaaaga atccaagtca
     7381 ctatctgaaa gaccatctac gatttctagt aatttttcat ttccatcaaa tttgtcatag
     7441 acgaattttt ttactttcgt ccgagtagtc atatgatgga tcttttccat tacttttccc
     7501 gatacaacga ctgctgtcgc tacactggca gcggctgcta cgcttaatcc gattgttact
     7561 tttgttgatg ttttcataag tatcagctcc tttttatcta tctccatcat agcatagaca
     7621 aaaaaataaa cgaactaatc cactcagtga aatctcaatc ctttagggaa aaagttcttt
     7681 actgttcctt ttacttgttt cccaaatccg acaggtatct tatctaatac tagcaaaacc
     7741 catccttgat tcccatcacg ttgaaatgtt tctcctgctg tgtaagattg ccattccttt
     7801 tgagtgatcg gcaagcaagg tatattctct atcttttttg tagcaagcgc taatgcatag
     7861 ctaggttcaa atcgattctt tttgaaatct cctaaatgca aacctgtacg tacgactttt
     7921 aaaccatcga gagaaggggc taactcagga acttcccaaa gatggtcgtt gaacactaaa
     7981 agtcttccag tagcttcata atgaaaatca tttgaaaact ccgtccagag tttttcctgc
     8041 tcttttgtca tttgcacttt actttttttt cgtgtcttct tttctttatg catctgattt
     8101 tgtccatgaa aagtcagctt tgcaacaaaa tgtccttcac cctgatcttt atgaggccat
     8161 atacgtattg ttttttccaa accagctacg cttccccatt cagaacgtcc tgaactaacg
     8221 gattgagtca aaggaatctc ctcaatcgtt actggataat tttctacaag ccagctaatg
     8281 atctcttcat tttcttctgg tgcaaacgta caagtcgaat aaatcagttg tcctttattt
     8341 tttagcattt ttattgctga agacaaaatc tcttgctgac gtttttgaca gtatagcgga
     8401 gattcttctg tccactcttt tattgcattt ggatcttttc ggaacattcc ttctcctgaa
     8461 caaggagcat caaccacgat ccgatcaaaa aagcccgaaa aatgagggac aagttctgcg
     8521 ggtgcatgat ttgtcactat tgcgttcgaa actccccatc gttctatatt ttctgataaa
     8581 atcttcgcac gtttcggaaa gatctcattc gtcactaata accctttccc cttcatttga
     8641 gcagctaatt gggttgattt accaccggga gccgcacaca aatccaaaac tttttcaccg
     8701 ggttttgctg cagcagctgt tccaacgatc attgcacttg gttcttggct atattcatac
     8761 ccagcttgat ggaggaaaga ctttccattg acagtgccaa gaaatccctc attgctgtag
     8821 ggagcgggtt gtaattcttc gctatggtaa gtttggacca tgtccaatcc tgccggtttt
     8881 agtggattcc accgaaatcc ttttttcacg cttccttgtt caagcgcaga aaaaaaatcg
     8941 gatgcttctt cgcctaaaag aagacgatat tttttgataa attgctgtgg taacgttgtc
     9001 gcttcctcct tcattccaat gtttcgttag acattttaca atctttttta cgaaaaataa
     9061 aggtggctga tctacttttt catgttgctg cctaaggtga ctgttccttt aagatatttt
     9121 ccaagtattc atccgtcacc tcgtttttat cccaaacagc gttcatcatt tcaagaaaat
     9181 cttgagaaga atcatctgag cgcaaacttc ccaatgcatt aagccatacc aattcaagcg
     9241 acttttcttc tttgatcttc gtgtgacctt tgacatatga gaaaaatggc cgcttaaata
     9301 gcgaatccat gtctaaatca gattttgcaa tgatttcacg aatactttca tggatagaaa
     9361 aaaaatcttt caataagtag acaatgctta aaacatcatc ggaactgcat tcagctaagt
     9421 agttttcaaa ataaacagtg atttcttcta atatcttctc ttttaacccg ctgattgatt
     9481 tgaaatgtgt ataaatcggg tatgtagaac aaccgcagaa ctctgctaac tctcttgcag
     9541 taattgactt cattccatat tcttccacgt ataccatact tttgaacagc aaatattctt
     9601 tactataatt tgttactctc cccatcattc ttacctccgt ctcttttcat ctacccataa
     9661 ataaataaca taaataattc taaaaatatt attgataatt atcaaaacat atttagttat
     9721 atccattaaa aatcaatttt tccgccttaa aaacaagaat atcttgacaa aataccctag
     9781 gaaataaaca atagaataaa caaggtaaca aaaaaattaa ataacgttat ataaaaaaga
     9841 aggcgacact ctgtgagaat aacacagact gaaatgactt tccactcaca gtttttgtct
     9901 aactatatac aaaaacagaa taaaaaggag gtatttatgc taattgaagc aagaaaaaaa
     9961 gagttacttg ttctacaaat ggtcattcaa aaaaataatt gttctttaca agaattatcc
    10021 aatgacttac atattccaaa acggacaatc aaagaactga tccgaaaaat aaatgtatca
    10081 ctcaagcaat ttttattgat tgatgaattt atttattcta atcataaagg agagatccaa
    10141 accaaagaaa ccgatcaaac taaaaagtta gctgtttttt ctaagttaaa attatgctac
    10201 ctaaaagaat ccaatcgttt taactatttg atgttactaa tcaattatcc acaaactgct
    10261 gtaccaaaaa aatatttact tgaacaactt tatatatcgc cctcctatct cgaaaaactg
    10321 acaaaacagc tcaatcattc cttaaaaaaa ttccatttac ggatcctatc tgtaaaaaat
    10381 tgctgtactc ttgaaggaaa tgagttatct atccgtctct atctttactt ttttctttca
    10441 gatacatttg gaggtaacga ttggccattt tcctcacttg aattaaatgc actaaaaatg
    10501 aacagtacag atgagcaaat agaaaaaatt tcaaaacaag aaaaaaatat ctacttgctg
    10561 ttaactttat tcatattacg aaacaaacaa caggcatatt ttccaaaaac ttcttctgaa
    10621 atcactgaat tgatggactt attgcagcat acacatgatt attcagaata ctttacttct
    10681 ttttcagtga gtcgcccttg tgaagagaca gaaacagaga gagcctactt taattatttt
    10741 ttctattgtt tttttccaaa tcaaatctct tttcgacaaa aacaggagat tggtttttta
    10801 ttttccacaa gcaaaaacct tatttgtcga caagtcggtc aattgatgac ttacttaact
    10861 caacagtttc ctctcaacca tttagaaaat aaaataccaa tttattttta ttttcttgtg
    10921 ttggcagttg tttttttcga actgttgggt gaatccagca gtagtttttc tacactttgc
    10981 tttccagaag ccacgtccaa tcattctagt tcttttatac aggaaaagaa attaagagaa
    11041 aaaatcgata caattttttc aaaaaatggg gaaagaaacc aaatcagtca ataccttagt
    11101 caattgatcc aacacttact acaaacagaa acgaaagagc agttactcat ccatttgcag
    11161 ataaccaaac agtttacagg aaattatcat cttcaaagcc atttgcagca gttatttcgc
    11221 aaagatgctg ttaaaattac cgcatattca gaacatgctg atttgatcat tacagatcag
    11281 catgagaaaa tttcagatga aacggagact ttctatctgg atacaacgca caatacagtg
    11341 ttatttggca agttaataaa agcggttcat gaactgtata tgaaaaaagg ttatgagaac
    11401 aaaacaaaga ggatgtgaca aaattcttgt cacatcctct
//
LOCUS       DACBZK010000080        11329 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.083, whole genome shotgun sequence.
ACCESSION   DACBZK010000080 DACBZK010000000
VERSION     DACBZK010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11329
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.083"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(51..560)
                     /locus_tag="IVD66_002311"
     CDS             complement(51..560)
                     /locus_tag="IVD66_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146502.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDVSPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(550..1275)
                     /locus_tag="IVD66_002312"
     CDS             complement(550..1275)
                     /locus_tag="IVD66_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146503.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(1498..3618)
                     /locus_tag="IVD66_002313"
     CDS             complement(1498..3618)
                     /locus_tag="IVD66_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP6146504.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            3848..5026
                     /locus_tag="IVD66_002314"
     CDS             3848..5026
                     /locus_tag="IVD66_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HAP6146505.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            5042..5800
                     /gene="aroD"
                     /locus_tag="IVD66_002315"
     CDS             5042..5800
                     /gene="aroD"
                     /locus_tag="IVD66_002315"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HAP6146506.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            5823..6308
                     /gene="ybaK"
                     /locus_tag="IVD66_002316"
     CDS             5823..6308
                     /gene="ybaK"
                     /locus_tag="IVD66_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HAP6146507.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(6379..7632)
                     /locus_tag="IVD66_002317"
     CDS             complement(6379..7632)
                     /locus_tag="IVD66_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP6146508.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            7749..9098
                     /gene="gdhA"
                     /locus_tag="IVD66_002318"
     CDS             7749..9098
                     /gene="gdhA"
                     /locus_tag="IVD66_002318"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HAP6146509.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            9210..10556
                     /locus_tag="IVD66_002319"
     CDS             9210..10556
                     /locus_tag="IVD66_002319"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HAP6146510.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(10864..11250)
                     /locus_tag="IVD66_002320"
     CDS             complement(10864..11250)
                     /locus_tag="IVD66_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP6146511.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3683 a         2032 c         2299 g         3315 t
ORIGIN      
        1 atcatgaatc gatcttctat accgcttgtt tttactataa aatgattgat ttagcccgcg
       61 ggctctaaac gatcaatata aggactttga gcaatagtag catcatgagt aaagagtaag
      121 ataccttgat tttcttcatg agctaaataa gaaagcaagt ggagtagctc ttggatctcc
      181 aatacactaa gttcatcaaa tgtatcttca ataacaatat tgtttcgctt ggaaagcaag
      241 gcatgaagta attgcagctt tactttttca aaagacgtca actcagctgc cgcacaatta
      301 agcaaggaag gagagacatc aagtttttct tgataggcca aacgatcttg tttgatttct
      361 ttttccggta catccaacag gacatggtct ttaagattca gataaggaaa catcggccaa
      421 tttttttgga tgatcgcaaa attatccagt tttgcaacaa gaacctcttt tttcaagtgc
      481 tccaatattt tatgctgttt ttcgagagga cacaaaataa cggtcaagtg ttcagcatga
      541 atcaaatatt caggtttcat tacgtccagg cctcctactt tgcaaatgat ggataaaaaa
      601 agtgaaaggg aatagactaa gaatgagaca gcatccactg agcccaataa gagtttgggc
      661 aaatccctta agtatatctg tgaaaaaaag atcattttgg aaatcgatgg taaaaaaagt
      721 ctgttgatcc atcggaattg taagtccgct taccgaagtc aagatatcac ggatatctgg
      781 cagttcagta gtctttaaga caagaaaatt gatcctttga agaagcgctt cataaactga
      841 ctggaagctt acgatccaca ataaaaccaa gatacaacaa agaaagagag gaaagaacag
      901 ctgccagaaa ataaaaagga ataatttggt tttagaaaga ccagtcaggt gccaattgat
      961 caattcctgc ttgttttgcc tgactgaata gtaaaagaaa aagataaaaa ggaaggcaaa
     1021 tagaaaaaat aaactgaata tgccttttat ataaaatcgg ctagctaatt ctaaagccgg
     1081 aagaagctct gtagatgcag aagcgccaat aaatgaaagc cgatcttgga cttgattggc
     1141 taaagccgat tgcaaatggt aaagagtcag gcatgctatc aataaaaaag cagaaaagct
     1201 tgaaaataaa caatagagta ttgtctgctt tttgtaataa attaatcgag cagtagcata
     1261 gcggattatt ttcatacttt tcacctctat aaaaagtata gaaaatgaat atgaataaag
     1321 tatgaaattc ctttagtgaa atcacgaatt aaaaccagaa aatattttgt aaaaagcaag
     1381 aggttgtgaa gaagctgccc tattctatta ccgtagatgc aagcttttga acactgttta
     1441 ttcgaaaaga ggagcagcga caataatttt gtcgctgctc cttttaaatt tattttatca
     1501 ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac gtttgcgttt tataaagatc
     1561 aacagttgat tgtccgttgt gttcactaaa gacactagtt gacttgtcac caagagattt
     1621 ttcagcttct tttaatttct ctaagccatt cttgtagtca taatcactgg tatcaattgg
     1681 gtctaatcca ctattcgtat agaaccgaag aagatcacca ttattgattt ggtcagaaac
     1741 agctaactgt ttatcaactt tttctttcag tgaatcaatt tcattctgta cttcctcagt
     1801 aggttcagta atagcttcac cagtttcgtt actatagatc gtaccaccgt agtaagtata
     1861 ttttggtgta acaaaatcac catcacggaa agaaacaagc tgttcatgat ctttcgagaa
     1921 tagatcttgt cctaactgaa tataattttt tgtatctaca cctagtaagt gaagtaatgt
     1981 aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt ccgccctgtg tttgtccagg
     2041 gatatggatc atataaggga cacgctgcat ttgtgcattg tcgtagtttg tccaagtaga
     2101 acttgttttt ccaactaatt cagctagatt tttatttctt gaattcgaga caccgtaatg
     2161 gtcaccgtaa aggacgatga ctgaattatc atacaagccg ctttctttca aataattgaa
     2221 gaattcttgt acggcggtat ctaaataatt ggctgtcgca aagtaaccgt tgatcgtttc
     2281 atcatttgta ttggctaacg ggaatcctgc ttcgtcattg gtgaattttg aataaggata
     2341 atggttagat acagcaatga attttgaata aaatggttgt tgcagacgtt ccaagtattg
     2401 tacggattgt tggaaaaatg gtttatcatg caacccgtat tggaacgaat tgtcatcatt
     2461 aacatcataa taagaagaat caaagaaata atcatatcct aaattcttgt atgtctcgtt
     2521 tcgattccag aatgtaccag cgttcccatg gaataccgca ctaatgtaac cttgtgtttg
     2581 acttaaaata tcaggtgcag cttggaaagt attttttccg cctaattgtg tgaacaagga
     2641 gccttgattc aagccaaaca atgaattttc catcagcgtt tccgcatcgc ttgtttttcc
     2701 tgcttttact tgatggaaaa agttgtcaaa actgaacgtg ctgttgctgt ggtaaagact
     2761 attgatgaaa ggtgtaactt catgctggag accattctca tctgtcaatt tataatcgat
     2821 caggaattgc tggaagcttt ctaaatggat ataaatcaca ttttttcctc tagcgagccc
     2881 gaacaaatcg tcatttggtg ctgcataatg ttcttttaca taattttcta cttctttcat
     2941 atcattggga cttgcttctg cccgcacttg gtttgtctgg taagtttgaa caccgtcata
     3001 aaccatgaaa gcattcaagc caagatattt gaccaaataa tcacgagaga atgttcgagt
     3061 cagcaattct ggacgatcag cttccgccat aaaaagattt cctgagaaaa tcataactgc
     3121 taatgtagag atcgcaaaag ccattcttgc tcggatcggg cgagggtcca acttgatttt
     3181 ttttgcaatc agcagaacag tcaagataat aaaatcgatc caatagatca catcatatgg
     3241 gcgaaacagt cgaatggcac tttctcccag accactcgct actttcccag cacctaaaat
     3301 cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa gtgacattcg aaaaaacaag
     3361 caatgtcaaa agaaaataaa tgaccatcat cgtgatataa gcaactctag ggcgtctgat
     3421 ataaagagca attccaagta ataacaatgt agttgcaata gggttgataa acaagataaa
     3481 gtattgaatg ccactttcga ttccgagatg gaaatcaact aaataggcaa aaatcgtttt
     3541 caaccaaagt aaaacgacta gtaaagaaaa aaatccgagc ctcttattca aaaaggcagg
     3601 tgtttttata catttcaaga taatcttcct ttctgcactt cttaatcaca gaagtgtcct
     3661 gaaaccatgt tacacagctc acttattctc atttatttta ctagtatgac aatatagtgt
     3721 caattgaaac cagaagttta tgctgtttca ttaaggtttt ctttaagctt catgaaaaaa
     3781 tgagcagtaa gacaagtcct atgttttttg ttatacttgg gaagagaaag ctaaagcagg
     3841 tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat cgattgaaaa aaggatatcc
     3901 actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa accacgcaat gggtggaatt
     3961 agttgattcg caaaaccaat ttatcgcaaa aggatatcta ggaaagcaga ataagggaat
     4021 cggttgggta ttgagccagc agaacatccc atttgatcaa tctttttttg aagaattttt
     4081 tgtgaagtca aaagaaaaaa gaactttctt tttttcagat gattctacta ccgcttttcg
     4141 tatattcaat ggagaaggag acgggatcgg cggtctgatt gttgattatt atgcaggtta
     4201 tgctgttttt tcttggtata acgaaacgtt atatgcacat cgtgaattat tgattcaagc
     4261 ttttcgtgaa atctacccgg aaatcatagg aggctatgag aaaattcgat ttgaatcagt
     4321 aaatctgcct gagagccagt tcatttacgg aaaagaggca ccggaaccct tgatcgtaaa
     4381 agaaaacgga gtaaaatttg ccgtttattt aaatgaagga ttaatgactg ggatcttttt
     4441 agaccaaaaa gaagtacggg gatcattagc agaaggtttc gcttctggga aaacagtttt
     4501 gaacatgttt agttataccg gcgccttttc tgttgctgcc gcaatgggag gggcaatcga
     4561 aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa acacaggaac agtttgaagt
     4621 gaatggtttg gatgtcgatc agcaaaaaat cattgttatg gacgtattcg agtatttcaa
     4681 atacgccaaa agaaaacaat ttttatatga catgattgta ttggatccac caagttttgc
     4741 cagaaataag aaaaaagtct ttcgcgtagc aaaagattat ggggaactgg tcaaggatag
     4801 tctggatatt ttagcagaag acgggatact tattgcgtct acaaatgctg cgaatgtctc
     4861 gatagaacaa ttccaaacaa tgattgaaga ggaattccat gccaaaaatg tttcttttga
     4921 acaacttgct ttatatcgtc tgccaaaaga tttccagacg acggatacct ttttagaagg
     4981 caattatctg aaagtgtttg tttatcaaat taaaaataac cattagaagg agcgatgcag
     5041 aatggttcgg gtaaagggat tgaatatagg aagcggtaga ccaaagattt gtgcgcctct
     5101 tatcggggcc gtccgagagg aagtattacg tgaagcagtt cttgcacgtg aagcaggggc
     5161 cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt ttttcttttg atgaagtagc
     5221 agaaacattg gttcttatcc atgagatgct tgatggactg ccgttattat ttacgtttcg
     5281 taccttagct gaaggcggag aacaagacat atcgatccgt cagtatcgcg acctttatga
     5341 acatgtgata cacacaggat tagtagatat ggtcgatatc gagttgttca aagtagaaag
     5401 tctaggaaaa agactgatag aggaaatcaa gtctttaaac attcctttaa ttatcagtag
     5461 tcatgatttt aaagaaacac cagcagaccc tgtcttgctt taccgattga atgttatgga
     5521 acattttgga gccgatatcg gaaaactggc agtaactccc aataatgaac gagatgtttt
     5581 gcggttgatg gagttgacta gacgggcaaa tgcttttgtc tccatgccta ttattacgat
     5641 gtccatggga aatcttggta aaatttctcg tctggttggc ggaacgacgg gttccgttat
     5701 gacatttggt tccttaagca gcgattctac ttctgctcca ggacaattac cggtcaaagc
     5761 attgaagcaa attattcaat tattaaatga accgttgtag aacaagtttg aggtgatatt
     5821 ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg tatggtcgaa caaaaaaaga
     5881 ttccctatac agagcacgaa tatgagtggg acgaaagcca cctaagtgcg tcatcggtcg
     5941 ctgaacagct tccagaaagc caatctcgta tatttaaaac actggttgct gtgggcaatg
     6001 tgacggggcc tcttgttgct gtgataccgg gagaagccga attgaatcta aaaaaattag
     6061 caaaagtttc agggaataaa aaagtagaaa tgctccattt aaaagatttg gaagcaacga
     6121 ccggatacat acgtggtggc tgctcgccta taggtatgaa aaaactattt cctacttatt
     6181 tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc ggctggcaga agagggctac
     6241 agatggagtt agcacctcaa gatatctgtg cattaacgag cggacaattt gcagatataa
     6301 aacaataaat catacgtata aaagaaagaa ggaggccggg atgttgtttg tccagtctcc
     6361 ttctttcttt tttatacatt atgctctttg cccggcattc attcctgcta catgccctgt
     6421 agcgaaagcc gctgtgatat taaagccgcc agtataacca ttgacatcca gtaattctcc
     6481 cgcaaaatac agaccatcaa tgattttact ctccaatgtt ttaggataaa tttcctttag
     6541 agaaacccct ccgccagtta caaatgattt ctcaatagga aaagttttgt tgattgatag
     6601 cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt ttttgagagg cttgttgtcc
     6661 tgtcagatga tccatttcaa gccgctcaag aaagaaaact aacaatcgct caggcaatat
     6721 accatgccaa gcattgacca agttcttttt ggttgcttta cttttttctg tcaatatatg
     6781 aataagctct tgtttggttt gtgtagggaa acaatccaga gaaagtgtca ctggttctcc
     6841 cgttttctct aattctttat tgacaaaact tgaacaacgc agtgcagccg gaccagaaat
     6901 accgaaatgg gtgaaaagta aatccatcgt atgttcagtc aatacacgac cttttttatt
     6961 taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga agtgttttct cctgaatata
     7021 cggttcatcc gatatcaagg gggactctgt cgcataaaga ggcgtcaccg tgtgacccac
     7081 tcgcttcacg atcttgtacc catctccagt agaaccagta gatggataag tccgtccacc
     7141 agttgttaag ataatggcag gagcatggaa ctcttcgaat tccgtgcgta taccgtaaat
     7201 tttatgttct ttgtggatca atttctctac tcgagtagag aatagaagcg tcacatctag
     7261 ttctttcaga cgattgagca atgcttcgat aatcgttttt gatttatttg ttacaggaaa
     7321 catccgtcca tgatcctctt cttttaaatg tacgccttgt gattcaaaga agttcatgat
     7381 atcgaaatta ttccattgcg caaacgtact atataaaaac tttccatttc caggaatatg
     7441 tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg caccgaccac cacctgtcat
     7501 cagtagtttt tttcctgctt ttttgttttt ttcgatcaag agtacgcgtg cgccttgttc
     7561 agctgcactg atcgctgcca tcatcccgct tgttccagcg ccgactacga tcacatcata
     7621 cagtttttcc attccctcac ctcaaggaaa gtgtagcata tctgaagaaa gaaaacagaa
     7681 aaaaatgttt tgagccaaaa gagaaaatga gctaaaatga gggaagataa gcaaaggagc
     7741 gtggaacgat gacaaacgca acagaatatg ttcaagcaat tcaagaaaag ctacatcaaa
     7801 aggatcaagg gcaagaagaa tttttacaag caatcgatga attcatgccc acggttatgt
     7861 cttttttgga cactcatccc gaatatatcg aaaagaatat cttagaactt ttaacggaac
     7921 cagaaagagt tattcaattt cgagtgcctt ggcaagatga tgaaggaaac tggcgagtaa
     7981 atagagggta ccgtatccaa tacaactcag ctatcggccc ttataaaggt ggattgcgct
     8041 tccatcctag tgtcaatcta agtatcttga aatttttggc ttttgaacag attttcaaga
     8101 atagtttaac cggtctgcca atcggtggag gaaaaggcgg aagtgacttc gatcctaaag
     8161 gaaaatctga taatgagatc atgcgttttt gtcaaagttt catgctggaa ttgtcaaaac
     8221 atatcggccc atcgattgat gttcctgcgg gagatatcgg tgtaggagct agagaaatcg
     8281 gctatttgtt cggcgaatat aaacgattga aaaaatatga tactggtgtg ttgacaggta
     8341 aacctttgga tttttgggga agtaagatac gtacggaagc tactggttat ggattagtgt
     8401 attatgtcaa acatctattg aacgaagaaa aagattcatt taatcaaaaa acagtttttg
     8461 tttccggaag cgggaatgta gccatttatg caatcgaaaa agtgcaagag ctaggcggga
     8521 aagttgttac atgttcagat tctagcgggt acatctatga tccagaagga atagatgtga
     8581 aactattgaa agaagtcaaa gaaatcaata gacaacgttt gacggaatac gcaaaccaac
     8641 gtccttctgc tatttatcat gctggagaat ctgtttggac attgaaagaa aaagcggata
     8701 tcgctttgcc atgtgctact caaaatgaaa tagacgaaag cttggccgaa atcttagtag
     8761 aaaatgggat caaaatcgta gcagaaggcg ctaatatgcc atgtacagta aaagctgttt
     8821 ctgttcttca tgaagcaggc gtgtggtatt gtccaggaaa agctgctaat gctggaggag
     8881 tagcagtatc tgctttagaa atgagtcaga acgtccagcg attgacttgg gaaagagagc
     8941 aagtggatga gcagctggat caaatcatgg aaacgattta ccatacgtgt cgccaaacag
     9001 cagccgagta cggcgacgaa aaaaatctgc ttcttggagc aaatgttgct ggatttgaaa
     9061 aagttgccaa agcaatggca gcagaaggtt tagtttgaaa aatgaaactt tcttggaaat
     9121 attgtcagca ttttgtttat ttgcttgaaa aataataaaa aaaaacgtaa agtattacct
     9181 gtagagtaaa cctataagga ggagaacaaa tggcacacat tcattttgac tattcaaaag
     9241 tagcaccgtt tgtcaacgaa caagagttag ggtacatgca aagccaagta acagcagccc
     9301 acaacgaatt acgggaaggt actggcgcag gaagcgactt ccgcggctgg atcgatttac
     9361 caacgaacta tgacaaagaa gaatttgcac gtatcaaaga agcagctaaa aaaatccaat
     9421 ctgattctga agtattagtt gttatcggta tcggtggttc ttatttaggc gctcgtgcag
     9481 cgatcgactt cttgaatcac acattcttca atttattaga tagcaacaca agaaaagcac
     9541 cacaaatctt ctttgccgga aattcaatca gctcaacata tattgctgac ttgatcgaag
     9601 taatcggtga tcgcgacttt tcagtaaacg ttatttcaaa atctggaaca actactgaac
     9661 cagcgattgc gttccgtgta ttcaaagagc ttcttgttaa gaaatatgga caagaagaag
     9721 caaacaaacg tatctacgct acaacagata aagcaaaagg tgcagttaaa gtagaagcag
     9781 atgcagaagg ttgggaaact ttcgtgattc ctgatgacat cggcggacgt ttctctgtat
     9841 taactgctgt tggtttgtta ccaatcgctg ttagtggtgc agatatcgat gcattgatgc
     9901 aaggtgccgc tgatgcaagc aaagcatact caagcgacaa actagaagaa aacgaagctt
     9961 accaatacgc agcaatgcgc aacattcttt accgtaaagg caaagtaact gagttgttga
    10021 tcaactatga accaggaatg caatacttct cagaatggtg gaaacaattg tatggtgaat
    10081 ctgaaggaaa agaccaaaaa ggcatctatc cttcaagcgc aaacttctca actgatttgc
    10141 actctttagg acaattcatc caagaaggac gtcgcaatat ttttgaaaca gttgtgaagg
    10201 ttgaaaaacc tcgtaaatca atcacaattc ctgaacaagc agaagattta gacggtctag
    10261 gctacttgca aggaaaagaa gtggacttcg taaatacaaa agcatttgaa ggaacattgc
    10321 ttgctcatac agacggtgac gtgcctaact tgctagtcaa aattccagaa atggatgctt
    10381 atacattggg ttatacaatg tacttctttg aaattgctgt aggtatttca ggttacttga
    10441 atggaatcaa cccattcgac caaccaggtg tagaagctta caagaaaaac atgttcgcac
    10501 ttctaggcaa accaggcttt gaagatcttg ctaaagaatt gaacgaacgc ctgtaagata
    10561 agggtttttc gctagattta aataatcagt gatagaaaca tgttcgcttt aaaatgaaaa
    10621 ctggtaccca tttaggtact caaacatact gcatcgttta ttcagaataa ggggctgtga
    10681 caagacgttt gtcacagtcc cttgtttgta tagaaatcga ttgattgcct tgctctttag
    10741 tttgttttag gactttaaga acagtgaggc tgacttcgaa ggttaattct gtttttttgt
    10801 tttctagaat cagtaagcaa aaaagcactc acttcgagtg cttttttgcg atatattctt
    10861 agcttaagat aggcctaatt tttcttttac agatgagggt accttatcgc tggtaattac
    10921 ttttttctct atgatccgct tttcgcttgc tttcaactgc aagatcgttc cttcggggta
    10981 agcagaacca ttggcagagt caccagaagt aatgacatcg aaatctaact gtcttttttc
    11041 accgttttca gcataagcat ctacgttgta tttaaaacct cttccaatta cttccccatt
    11101 atctgctttg atatcagttt ctgcaggcat tggagctttg actaccgcat aataatcttt
    11161 acctacataa gtagactgat agtagtccca acctttccat cctataaaag caatcaatat
    11221 gataacgatc aaccctaaaa tttttttcat gaaagatctc cttttttatt tttattatac
    11281 ccgtggtgct agttaatttt aatatcctaa agaatatctc aaagttcct
//
LOCUS       DACBZK010000081        11185 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.084, whole genome shotgun sequence.
ACCESSION   DACBZK010000081 DACBZK010000000
VERSION     DACBZK010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11185
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.084"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="IVD66_002321"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="IVD66_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAP6146512.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="IVD66_002322"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="IVD66_002322"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HAP6146513.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="IVD66_002323"
     CDS             complement(2169..2906)
                     /locus_tag="IVD66_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAP6146514.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="IVD66_002324"
     CDS             complement(2997..3524)
                     /locus_tag="IVD66_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HAP6146515.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="IVD66_002325"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="IVD66_002325"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAP6146516.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="IVD66_002326"
     CDS             complement(4401..4886)
                     /locus_tag="IVD66_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HAP6146517.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="IVD66_002327"
     CDS             complement(5039..5236)
                     /locus_tag="IVD66_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146518.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="IVD66_002328"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="IVD66_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HAP6146519.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="IVD66_002329"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="IVD66_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HAP6146520.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="IVD66_002330"
     CDS             9211..9423
                     /locus_tag="IVD66_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HAP6146521.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="IVD66_002331"
     CDS             9425..11104
                     /locus_tag="IVD66_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAP6146522.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3244 a         2416 c         1965 g         3560 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgtt
//
LOCUS       DACBZK010000082        10936 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.085, whole genome shotgun sequence.
ACCESSION   DACBZK010000082 DACBZK010000000
VERSION     DACBZK010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10936
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.085"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..154
                     /locus_tag="IVD66_002332"
     CDS             <1..154
                     /locus_tag="IVD66_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP6146523.1"
                     /translation="SLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTL
                     RYSLGY"
     gene            complement(235..1218)
                     /locus_tag="IVD66_002333"
                     /pseudo
     CDS             complement(235..1218)
                     /locus_tag="IVD66_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311512.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            complement(1613..2455)
                     /locus_tag="IVD66_002334"
     CDS             complement(1613..2455)
                     /locus_tag="IVD66_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP6146524.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGI
                     PYINNLGLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQH
                     LEIS"
     gene            2780..3196
                     /locus_tag="IVD66_002335"
     CDS             2780..3196
                     /locus_tag="IVD66_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP6146525.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            3193..3663
                     /locus_tag="IVD66_002336"
     CDS             3193..3663
                     /locus_tag="IVD66_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6146526.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            3677..4450
                     /locus_tag="IVD66_002337"
     CDS             3677..4450
                     /locus_tag="IVD66_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6146527.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAASPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            4464..5276
                     /locus_tag="IVD66_002338"
     CDS             4464..5276
                     /locus_tag="IVD66_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP6146528.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            5330..6295
                     /locus_tag="IVD66_002339"
     CDS             5330..6295
                     /locus_tag="IVD66_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP6146529.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            6432..9155
                     /locus_tag="IVD66_002340"
     CDS             6432..9155
                     /locus_tag="IVD66_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6146530.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESQILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGGSIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            9168..9800
                     /locus_tag="IVD66_002341"
     CDS             9168..9800
                     /locus_tag="IVD66_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP6146531.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            10005..10232
                     /locus_tag="IVD66_002342"
     CDS             10005..10232
                     /locus_tag="IVD66_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009320234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HAP6146532.1"
                     /translation="MLQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEV
                     IPENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            10301..10567
                     /locus_tag="IVD66_002343"
     CDS             10301..10567
                     /locus_tag="IVD66_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAP6146533.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            10557..10826
                     /locus_tag="IVD66_002344"
     CDS             10557..10826
                     /locus_tag="IVD66_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP6146534.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
BASE COUNT         3625 a         1742 c         2137 g         3432 t
ORIGIN      
        1 ttccttagaa aaattaggtt gtcaaaattt caactcacgt tctgttaaag ggctagagag
       61 tagatttgaa agcatattac tggcttacag tgttctatta agtcgagcac aacgacgttt
      121 tgaaggaact ttgagatatt ctttaggata ttaaaattaa ctagcaccac gggtaaaata
      181 aatagttttt ctatcaagta tattgaacta cgataaattt gttattttgt tttgtttaat
      241 ttcgttgtac ttattggctt tgacttcgat ttctttaaat actgggtaat cggtgtccgg
      301 caaagctagc aaatctgttt tttctgtgtt ccatagatca ttgataatga catgtttttc
      361 gtaatggatt cgctctcgat cgtgtgacag ctccaccgct aatgcctcgt tgaaactggc
      421 gaaatccttc ataatcggtg tagatgaaaa gaagttgtac cgtacatagc cgactttgtt
      481 ttccatacta cctttctcgt ttccgctacg tggattgcac acctgtgtct caaaaccata
      541 gtgcatagaa aatcggagga aaccgtcagt cagcaccgct tgttcagtct ttgtttttgt
      601 ctaagtaacg gccgttgaca tattatcaat ccgtattttc cgaggaacgc cacctgattg
      661 gctgaagagt tctttcatgc cttccaacaa acattcttga ttctcggcgg ggagtacaac
      721 ggcgaatcct gcattactaa aagggaaagt catcactaat accttcacat ctttaaacgc
      781 tccatcgtga caaacttcca tcgtaccaaa atcaagttgc gcttctgctg gcgggtgttc
      841 aagacgctca aagccttggt cttccagtgt ttccaagtag tgtgtcgctt tccaatcttg
      901 aatgaataca cagactgttc ggtaggatcc tggaaagcca tcggctttta aagcagtagt
      961 cattgcttca gcagtcctac gctttttatt tggcagctta gcatcttctg aaagccatag
     1021 ggaaacgatg cctccccact tttctgtata catcatacca gtctttttgc gtgctttagg
     1081 ttgcggcagc aaatcatcat ctgcatattt tttagccgtg cgccaattta catctagctc
     1141 ctttgcaata tgattaatgg atttatcatg attatttcgt aaatttctga tagtattaat
     1201 atcggtcatt gtgagcatac ctttcttacc tccagttaca gtgtcgagac tataacttta
     1261 gaggagtttc aggttgcccg caatggcttt ttatcttaac ttaatcgatt tgcggagttg
     1321 tgtagttttt cgttgcactt gtatgtactt ttattctgcc ataaacagct taatgaatgt
     1381 ccacttgaaa aagtgaataa acgaaataga tgactcgatt taataaggaa gtaaacccac
     1441 acagaaatat aggtgatttt ccttgaatga ccaagatatt gaaagttagt gaaaaaacac
     1501 aaaaaggtag ccctattcac agaaggtctg ccttttgtgt tatcgccagc aaacattaga
     1561 gggggtattt catatagctt ttgtcctctc gacagtccta tcagtttctc ttttaactta
     1621 tctctaagtg ctgtccagtt ttaatagctt ctagcttgtt tcctaactgt gtttttaata
     1681 tgttgaaggc ttttgaacct gtgcagtggc aagtaaggat tttttctact cgtgagtcat
     1741 tcaatttatt tccaattttc attacctctt gctcaggtag acctaaatta tttatataag
     1801 gtatgccaat catatggaag ccaccaatta ggtattttat gggtttagtc ggaaatgttt
     1861 caagagcaat ttccatcata tcgataatgc catgatgact acagccagta aagacaatca
     1921 gaccgtcttc ttgctcaatt acgaccaata attcatctga aaaatcatca taaacaaatt
     1981 tatcatccat ctttttgtat aaattcttgg tggtcgagtt tgctttgcct agggggatga
     2041 tatggaagct cggagcaagt tctgttttcg tttttattgt atgtaaattc tcatgcattt
     2101 taaggatttc atttttagga ataccaacat acagaaacgt ggttaaaatc tttaaataat
     2161 ggggtaaagt tacaccttca gctgtataaa taggggcgtt tcctgatttt aaatatctta
     2221 acccgccggt gtggtcagaa tgaccgtgtg aaataatcac tgcctccaga tcattcaaag
     2281 tttcccccat tttagtcgca ttatagacta attttttatt agcgccagca tcgaagagat
     2341 atttcttccc tgagtagtta attaagagag ataacccatg tccactttta aagttcaaat
     2401 ttattcttga gttttcaaat aaaaccttga tttccactat aacatctcct ttcacatgaa
     2461 cgtgtattca tatattgtag cacattaagt tctatttttt gttgtaatta ccgaaaaaaa
     2521 tattaatgga cgctttttac gctttatttc gtatgtggaa gaaaatttct taggatgtgg
     2581 cgggggattg gggcaaagct aaattccaat tacagtgatc atttaattag acacctttaa
     2641 atacccacac tttcatcaac actataattt agggaaagaa aagtgttggc atgatataga
     2701 aaaaccttta attaacagcg tttcctaaaa ttggcacgca tcttgcttat agaaaagcgt
     2761 aaggatagga ggaatgaaaa tggcaactat aattcttgcc agccatgggg aatttgctca
     2821 aggattaaag caaacagcga caatgattat tggagatagt gtaccaattc atgccttgtc
     2881 agcatttaga gatgaagatg aatctatttt ggtacaaata aaaaaacttt tagccacaat
     2941 agatatagaa gaaacctaca ttttaactga tattctaggt ggtagtgtga ataatgatat
     3001 gctcactatt attaaagagt atgagggatt gcaattaatt actggaatga acttaccttt
     3061 agttatttct attgcaacct ataatggaaa aattggggaa agtgagctag aaaagcttat
     3121 taaagagagt caacaatcag tgattgattg tagaaaatta ttagtagaac aacttactgg
     3181 aggagatgac ctatgattaa gttagtacgt attgaccatc gtttgttgca cggacaggta
     3241 gtattttctt ggagtaaatc attaaatatc aatcgtatta ttattgccaa taaagaggca
     3301 gcgaatgatg aattcaaaaa aatgtctttg aatttatcta aaccgactgg cattaaatta
     3361 acaatttttt cagttgaaca gttactagaa aaaatgccta aaatcgaaac acttaacgaa
     3421 aatatcatgc ttatttttgg taatacaaaa gaaattcgtc aattttgtga agcctatcct
     3481 aaagtacaag aaatcaacta tggagggata atcaaaaaag aaggttccaa gcaatttagt
     3541 aatgccattt tcttgaatga atctgagcaa gaagatgcca aaaaattaaa agctcttggc
     3601 attaaacaat ttattcaaca ggtaccaact tctaaaaaag aagatttgaa tacaatgtta
     3661 taaaggagga atgaaaatgc tcgttcagtc aattggttta gggttaatcg gtgttttttg
     3721 tattttagac tcaaggcttt taggaagaat gaattttgaa cgaccgttga ttgtcagtac
     3781 gcttgttggt ttggtacttg gagacatgga aaaaggatta attgttggag cctctttgga
     3841 attgatgtcc ttaggattag taaatatcgg agctgcttca ccacctgata tgaatatggc
     3901 atcaattatt gctacagcct ttgccatttt atcaaatgcg aatgcagaag cagcattaac
     3961 gattgccatt ccaatttcag tgttaggtca aatactaggt atcttaatgc ggacgatttt
     4021 gtcaaatttg actcacgttg cggatcgctt tatcgaacaa ggaaaattta gccaagcaag
     4081 gagaattcat atactttatg gctcgggatt atatgctctc atgtatttta ttcctatttt
     4141 tctagcaatt tattttggaa cgaatcttgt ttctcagatt gttgatgcga ttcctgagtg
     4201 gctaacaaat ggcttaacgg ttgcaagtaa aattttacca gcatatgggt ttgcgttgtt
     4261 attacaaacg atgttaacga aaaaaatggt gccattttta ttacttggat ttttaattac
     4321 tgcttattct ggattgggaa tcattggtat tgcagccttc gcatgtattg ttgcgtttgt
     4381 catggttcaa gttcaaggta aaaactcaaa tggtaaccaa aatgagccag atccattaga
     4441 tgacttataa ggaggtagat taagtgaaag agaaagatca aaatgcatgg aaatatcggc
     4501 agttcttatg gcgttcatgg gcaattcaag cctcatggaa ctatgaacga caaatgaaca
     4561 tgggttttat gtacggaatt gcaccaattc tagataacat ttacaagaat ccagaagatg
     4621 aagcaatgaa gaaagaagct tacgagcggc atatgatgta ctacaactgt acccctcaaa
     4681 caagtgcatt tgtgttaggg ttaactgctt ctatggagga gcaatactac gaagaccaag
     4741 aaaactttaa tccggaatca atcagtgcag tgaagacttc tctgatggga ccgctatctg
     4801 gtgttggtga ttctttcttt caaggaacga ttcgggtatt agcctttgga ctaggaatta
     4861 atttagccca acaaggtagt attttaggtc caattctagc aatgttaatt tcctttgtac
     4921 cttccttttt agttacttac tatggtggga aaattggcta taacatgggg aataaatact
     4981 tgtctaaact gtatcaagaa ggtttgatgg ataaagtaat gtatgtttgc tccattgtgg
     5041 ggttgatggt cattggttcg atgattgcca gcatgatcgg gattacaaca ccaattcaaa
     5101 tgggtaaagc ttttgtctta caagatgtat tagatagtat tatgccacaa tttttaccat
     5161 taggattaac cttcttcatg tactggttat tgcagaaaaa ggtcaaaaca ggatggatgt
     5221 tggcaatctg tttagtcgga ggaattattt ttagtttgtt aggtatctta caataaggga
     5281 ataaccaata aatttggttg aataatataa ataaggagga attcaattga tgaattcaaa
     5341 agaaattgtt aaagaaatcg tagcgaaaaa agaggtaaaa tcaatcgtat ttgttggctg
     5401 tggcgcttca aaagcggacc tttatcctgc aaagtatttt ctagaccaaa atgcgaagca
     5461 gttacggatt agtcattaca cagccagcga atttaactat gcaacaccag catctgtaga
     5521 tgagtcaact gtcgttattt cagcttcttt aggaggtacg actccagaaa cagttgaagc
     5581 taacgcagta gctaaagaaa aaggtgctac agttattagt ctaacacgaa gcattgactc
     5641 accgttaaca aaagatgcag attatgtaat ttatcatcga tttgcagaga actatgctgc
     5701 taaattagaa aaaacaggct actgtttaga attggcagta gaacttttac atcaagtaga
     5761 aggttatgac cattatgaag caatgcaaga aggatttgct actatctatg atcttgccca
     5821 aaaaagtgca gaatcagctc gtaaagatgc gaagaaattt gctgaacgct ttaaagatga
     5881 aaaagttatt tatgtaatga gtagtggtgc tacacatgaa gtagcatact caacatcaat
     5941 ttgcttgatg atggaaatgc aatggattaa ttctggtacc ttccattcag gagaattttt
     6001 ccacggacca ttcgaaattg tggataaaga cgtaccgttt atattattaa tgaatgatgg
     6061 aaaaactaga aatatagatg ctcgagcatt aactttcctt gaacgctttg atacgaaaac
     6121 agaagttgta gatgccttgg attatggctt gtcttcacat attgctaaag aagtcttaga
     6181 ctactttaac ccattcgtga ttactgcagt atttagagtt tatgcagaag aattgtcaga
     6241 agcaagagaa catccattaa ctaagagacg ttatatgtgg aaactaactt attaaaaaat
     6301 agatcaaact aaataaggtg gcttgagaaa ttaagccacc ttgttttctt caatgtgatt
     6361 ttatacatat ggtaaaataa ctagtacata tggtaaaata actagtacat attgtgaaag
     6421 caggtggcaa gatgcagcga ttaaatgact atctttatca actaacattg cttttgaaat
     6481 ctacgccttc agataattat tcagctcgca gtatttcgca agctctacag ttgaatagaa
     6541 gtacaatcag tagctactta aatgaaggtg ttcgtgaagg gcttttcata aaagtaaaaa
     6601 gttacccggt tttattttta catagaacag ctcttgaaga actacatatc acactgaata
     6661 actccgaaat agaatcaatt gaaagcttgt taacaatttc tcaaaaaccc gcattagatc
     6721 aagtaattgg ctctaaagga agtttgaaag aagcaattga tcaaattaaa acggcagtct
     6781 tatatcctgg aaaagggttg cctttattat tgatcggcgc tagtggatca gggaaaacct
     6841 ttctagcgaa taaaatatat gaatatgcag tagaagaaaa ggtcattcac acatcggcac
     6901 ctttcataga ttataattgt gcacaatatg tgagcaatcc agagttacta tcctctgctt
     6961 tatttggcta cacgaaagga gcatttaccg gagcaagcca ggagcatact ggtttgctag
     7021 aaaaagccga tggaggagta ttgtttttag atgaagtgca tcgcttatct gaagaagggc
     7081 aagagaaatt atttacattt atggatacgg gtgaattctc tcctatgggg gataatagta
     7141 ttcggaaaaa agccgatgtt cgattagtct ttgcaacaac agaaaatata tatacgactt
     7201 tcttaccaac ttttcttagg agattgccag ttattgttaa tctacctaga tttcaacaac
     7261 gtccgtcgtt tgaacgtctg tcattgattg atgaattttt tgtttctgag agccaaattt
     7321 tagctaagga actatctgtt tctgatgcat tgattcattt cttaatgaat agtgattttg
     7381 aaggtaacgt ggggaatatt aaaaatatta tcaagtatgc ttgcggaaac gcatatatcc
     7441 accagaagag tcagcaaaca attcaagtta aattattgga tatgccttta gagtacagtt
     7501 ataaattcaa ggagcaacta aataaaccca gaaagaaaag agcagatcga atctactatc
     7561 cagaagaaac acgacaagtg caactagaaa gaaacaatca gctttttgtt caattttttg
     7621 accaattact tactggattc tctgaagtga ttgaaaataa caaggatatt aaactatttt
     7681 tagaagaaat ggttaccaag gtaacacaag taatggatac gcttattttt caagaggatt
     7741 acgaaaaaga gcagtcttta tacgccattc taaactatca tattcgtcaa agtattgatt
     7801 ttatgcgaga aagctacggg tttgaacaag atggtaaccg ggtagtcgct ttggccaact
     7861 atctatatgt caaggataat caagtgattt ttgaaaatag tcttcaagaa aagaaaacca
     7921 aagatcagct taacgaattt tttgctaatg ttcttgaaac cccttattgg tatgcaaaaa
     7981 aaatcttaag ccttttatct gagtgtttag atcaacctgt gtatgaagag gacattttct
     8041 ttattacgct atatttttat agtttgaatg tcacgaatgt taaaacaggt attaagagta
     8101 ttgtgctagc tcatggttat tctacagcta gtagtatggc gaatgttgcc aaccgtatgc
     8161 tgaataagaa cgtttttcaa gcttatgata tgcctttaga tattacatta gagaaaattg
     8221 aagcaaaatt gattcaattc cttggagatt atcgaacaga ttcaggcttg attttattgg
     8281 tagatatggg ttcactaaac caactaggcg gtttattagt gaatcatcta aatggaccac
     8341 tgttaatcat tgatcatatc aatacaccgt tattattgga agtcggccaa caagtattaa
     8401 acaataaaag tatcaccgaa ataggagcag aaattgaaac aagtcttact ttcaaaaagc
     8461 agttactact tcccaagaaa aagaaaaaga aagccatcat tacttgttgt tatacaggga
     8521 ttggtagtgc gacccagatt caggagattt taacgaaatg cttgaaagat gcagttagag
     8581 aattagtaat tattccgtat gattacaaaa agctgttaga aaacaagaat tttgagactc
     8641 cttttcaatt atacgatgtc atcatgattg taggtacaga agatcccaaa attaatcaga
     8701 ttccatatat tggattagat cgcctgatta atgggggaag cattggcgaa tttgttcatt
     8761 acttggaaaa agagctgact attgaagtga acgatttaca aaaagaatta attttcaatt
     8821 tttcaattag taaaattgtc gaaaatttaa ccattttgga tccagataag gtgctatctt
     8881 ttgtacaaaa agcaattaaa gaattatcga agttattaaa ttttgatttt tctaataatc
     8941 agctgttttt gttgtacctt cactgtagtt gtatgattga acgaattgta cgtaaagaaa
     9001 gtgtggatga gcaagaggac attgaagaat atatgcaagc aaatggagaa ataatggata
     9061 aaattcatag cgcttttttt gagattgaaa gggaatacac aattgaaata ccagatttag
     9121 agttgcgatt attgagcgat attgttcaag gataggagtg aattcgaatg acaatgggag
     9181 taatttttga tatggatggg gtactcatag atagcgagac attttatttt gagagaagaa
     9241 tgaacttctt tcaagaactg gagatagatc caggatcaaa ccagattgat gattatgtgg
     9301 ggaaaacaga agctgcaata tgggaaacat tagttcctga ggacaaatca ttaagagagg
     9361 aactttatcc gaaatatgta gattatcgaa aaacgcatcc aattgatttc gctaaagctt
     9421 tacgaaaaga agtgaaaccg ttacttgact tcctcaagaa gcgggatata ccattggcac
     9481 tggcatcttc ttctccagct gtcgagatag agagtatgct cattcaatgt gaacttactg
     9541 aatatttttc ctttgttata agtggtgagt cattaaaaca aagcaaacca catcccgaaa
     9601 tatatttaaa agcgaaacag caattagact gtgacttctt tattgcagta gaggattcaa
     9661 cgattggtat taaatcagca aaggcagcaa atatctatac ggcggcacta aaacaaccaa
     9721 tgcaaatcga tcagagtgaa gcagacatac aaattgaaag tctacaagaa ctggaacaaa
     9781 ttgttttaga aaaaggttag tgaattaatg gaaataaggc tatatatctg tgctagctat
     9841 tttgactaac caaaaaaact tgctataatt caggtgtagt aaaaggtgct ggtaacacct
     9901 tttacgaaaa tgcttcggca gtgataatgg gattggcttt ttaagttttt tattttgttc
     9961 gcaatcccta aggtcatgtg aatgatccta gggattgcta gaatattttg caacagaacc
    10021 aaaatacgaa tagttatcaa gcagccatat tgactgcggt caatttagga ggggatactg
    10081 atactactgc tgccgtaact ggtgctcttg cgggtattct ttacgggggt gaagtgatcc
    10141 ctgaaaattg gagaaaatcg cttcaaaatg accagcttct taaaacgatc agtcagagat
    10201 tttgcgatac cgtgctatct caaagaattt gaataatgga tatgatgcaa atcttgtttg
    10261 tactaacgtt gtattgacaa aaaggatttt atttagtaca atgttagtac aaatgatgaa
    10321 cggaggtaga atcatgtctc aatcaaccat tacatttagg attcccgacg atgaaaaaga
    10381 actggtatta gaatatgcaa aagcacacaa ttcttcattg accgaacttt atcgaaatgc
    10441 tgtactggat aaaatcgaag atgaaatcga tctacggact ttacggagtg caattgaagt
    10501 ttccaaagag aaaaaagaga gtggtatttc tcaagaggaa atggagaaac tgctaaatga
    10561 attataaagt catctacatg ccgcaagccc agaagcaatt aaaaaaaatg gacagaaacc
    10621 aagctaaaat aattgtcgcc tggatcagaa agaatttaga aaacacgact gacccgcgtc
    10681 agcacggaaa aggtttgact ggaaataaga gtggggaatg gcgctatcga attggaaact
    10741 atcgaatatt ggctaatatt tgtgattctg aaattgaaat ccagatattc tcaattggac
    10801 atagaagtac aatatataaa agataaccgt ttttggaacg aagtagagtt tcgaaagtca
    10861 atgtataatc ttttgaattt tgcataatac cacaggtaga aactacccga tactatcggt
    10921 tggtttctgc tttttt
//
LOCUS       DACBZK010000083         9328 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.086, whole genome shotgun sequence.
ACCESSION   DACBZK010000083 DACBZK010000000
VERSION     DACBZK010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.086"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            317..1102
                     /locus_tag="IVD66_002345"
     CDS             317..1102
                     /locus_tag="IVD66_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP6146535.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            1115..1966
                     /locus_tag="IVD66_002346"
     CDS             1115..1966
                     /locus_tag="IVD66_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HAP6146536.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(2090..2542)
                     /locus_tag="IVD66_002347"
     CDS             complement(2090..2542)
                     /locus_tag="IVD66_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6146537.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLMQTDISLVS"
     gene            complement(3007..3375)
                     /locus_tag="IVD66_002348"
     CDS             complement(3007..3375)
                     /locus_tag="IVD66_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chaperone"
                     /protein_id="HAP6146538.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            3525..4007
                     /locus_tag="IVD66_002349"
     CDS             3525..4007
                     /locus_tag="IVD66_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HAP6146539.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSEHMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLLNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            4044..5054
                     /locus_tag="IVD66_002350"
     CDS             4044..5054
                     /locus_tag="IVD66_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HAP6146540.1"
                     /translation="MISYPLLERNTTIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGINLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(5169..5882)
                     /locus_tag="IVD66_002351"
     CDS             complement(5169..5882)
                     /locus_tag="IVD66_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146541.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSSDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPTHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
     gene            complement(6072..6662)
                     /locus_tag="IVD66_002352"
     CDS             complement(6072..6662)
                     /locus_tag="IVD66_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HAP6146542.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQKEGWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            7185..7856
                     /locus_tag="IVD66_002353"
     CDS             7185..7856
                     /locus_tag="IVD66_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6146543.1"
                     /translation="MEPKDKYLDYARVNKDKFIETIIKGKIPDDEKDAVFMAGSPGAG
                     KTEVALGLAENYDNHVVIDADYFRAQFPEYNGKNSSVFQKASSWLVEQSLKYVLEHGY
                     SFILEDTFAILSAEKNIIRALKNNFRVTIFYVYQDPKVAWDFTRKRELAEGRHVPKEM
                     FINAFFKSRENIEKVKNRHPEVVLHIMIKDYQNDISEVHYAADNIQLVLPNTIYFKRV
                     GGGIT"
     gene            8498..9268
                     /locus_tag="IVD66_002354"
     CDS             8498..9268
                     /locus_tag="IVD66_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HAP6146544.1"
                     /translation="MNPTLITKKELLKKLDISTGVLADLIRNGMPKEGEMFNLDKIIT
                     WRENWSKNILGELEVGRVYTNKEISEKFKCFKQGGMRRSHQTNTLVLFSDQTGSNVYK
                     DKWLNGILQYTGMGLKGDQVLDKNQNKVLANSKSNFVKIHLFETFKPKEHTYLGEVYL
                     AGQIYTVNEKDSSGNSRKVYKFPLALINQEQLIEDKDIYNQEENQTRHIRNLSDAKLE
                     EEARKVSNYNKKMAAKYVNEEEFCFSKTKIYKRTRGAS"
BASE COUNT         3209 a         1445 c         1763 g         2911 t
ORIGIN      
        1 ggctgtgaca aaagtcttgt cacagccttt ttttccaaat aaatggtttt tcagaagtag
       61 cttcttcgga aataagccga aatttcacaa aaatttgaga agtaattttt gtaaattact
      121 tcttatttct tgaagctggc cacttctgtc acaacctctt tctttataga aataaaagga
      181 cactagcaat tcatgaaaac gattgctaga gcgtatcatt tgctttagac tatatatctt
      241 ggtgtacact cactttaaga cggaaataaa agttatccgt aataacaggt ttaggtatga
      301 aaaaggagtg ggtactatgt ataaggaatt agaaaacaaa gtcgcagtag taactggtgg
      361 ctcaaagggg attggaacag cgattgctca acgattcggg aaagaaaaaa tgaatgtagt
      421 tgtcaactat aactcggata aagaaggagc agaaaaagca gtcaaagcaa tcgaagaggc
      481 aggcggaaaa gcagtctctg tacaagcaga tgtcagttct gaagaaggaa tacagcgttt
      541 acttgatacg gctttagaaa attttgggac actggacgtt tggattaata atgctgggat
      601 ggaaaatcag catccaaccc atgaacttag ccttgaagat tgggaaagag tattaaaagt
      661 caatttgact ggcgttttta tcggaacgaa agcggcttta aattacttta cagagaatga
      721 taaaaaagga aatatcatca atatgtcttc tgttcatgaa caaatcccat ggccaacgtt
      781 tgctcattac gctgcttcaa aaggcggagt aaaactattc accgaaacgg tagcaatgga
      841 gtacgcacca aagggaatca gaatcaatag tataggacct ggtgctatcc gtacacctat
      901 taatgcggca aaatttgatg atcctgaaca aaaagaactc ttggaaagta tgatcccact
      961 aggacgcgta ggtgaaccaa aagaaatagc ggcgacagct gcatggttgg cttcagacga
     1021 atccagttat gttacaggta ttacactatt tgcagatggt gggatgactt tatatccttc
     1081 tttccaaggt ggaaaaggat aagggtgaat aaaaatgggt ttattgattg cattgatccc
     1141 ggcagttggg tgggggatcc agccactgat tttgaaaaag attggtggca gaccaacaaa
     1201 tgagatatta ggaactggta ttggagccgt gctcgttggc ttacttgttc aattattcgc
     1261 ttctccagct ggtatttcag tgactacatt tttgattagt ttactttctg gtgcattctg
     1321 ggtcatcgga caaacaggac agtatacatc tttcaacttg attggtgttt ctaaaacgat
     1381 gccaatttcg actgcattac agttagtcgg aacctcattg attggtgtct tcgcttttgg
     1441 agaatggtct ggaagtatgg gaaaaatcat tggtgcagca gcaatcattc ttcttgtatt
     1501 tggttctgct ttaacggcaa tcagtgatga tcctggaaaa aaaggcggta tcacaaaagg
     1561 aatcagtcta ttagcatcaa caagtattgg ttattgggtt tacagtgcat tgcccaaact
     1621 agttgatgca agcggacttt ccattttctt tccgcaaatg atcggtgtct ttttaggggc
     1681 agtgatttat gtgattttcc gaaaaccaac cgcattttct gaagacaaga gttggaaagc
     1741 aacaatagtt ggagccatct tcagtgtgtc agcattggct tatatttttt cagcaaatga
     1801 aaatggggtt gctactgcat atatcattac acagctaaac gtagttatct ctacattagg
     1861 cggtatgtac atcctgcatg aaaataagac accaaaagaa aaaaaattaa cgattatcgg
     1921 attattgctg atcgtagtag gaagcatggt cacggtcttt atttgaggat aaagatggta
     1981 aaatctcatt tattaaaaaa atatttgttt gaaccaaaca gtaagtactt ataaaaaaat
     2041 agcgctagaa tttccaacat ctctggaatt tctagcgctt tttaattgtt taagatacaa
     2101 gtgaaatatc tgtctgcatc aataattttt cattgatcca ttgactaaag tttacgacat
     2161 aattgaagtt accaccgatt agtatctccg catgattgtc tttataaaga tcgtattgta
     2221 aaagacggtc ttttttattt gcgtaaacat cgttatggta ctggactaat tgttctcgga
     2281 attgattgat tgctgtaaaa tcacgatact gaaggttgaa acgcatcgtg attggtgcat
     2341 ttagcatgaa tcgctgcatt tcttttgctg cttcctctgc ttgatctccg tataggaact
     2401 caaaaagatt acgttcagaa aatttccatt gcccgccaac ctttgttcct tttagttttc
     2461 cttcatgaag ataatttctg atagaacgtg tagtaacacc taattgttcg gctaattcat
     2521 ttactgagta aaaatctttc aatgttcacc ctcctatgtg aatggttcta ctgacttagt
     2581 tgatatttgc ttaatcacga aatgtagaaa gaacgatttt aattaaggtc attgtaaaaa
     2641 tcaagtcaga aaattctaac ttttctttct ctaaagaaat tcgttctctc ctaaagtgat
     2701 attatattta aatatacctg aaaataatgg gcagtattat gaaagatcac tgatattttc
     2761 tcgtattttt tccttattca aaagttttgc aggaaaattg ctgaaaaaat aattttacta
     2821 agtggaaaat tcaaagccat tcaatcagtg atttttttca gcacaagaaa gactccttat
     2881 aaaaatagca gatactttgt caattaagtg tttaaccagg gatgataaaa aggataggat
     2941 tgaacaaaac ctgtataagc tgatgaatag tttcctcgcc agtaaaaggt ttattcgtat
     3001 aaagctttat cgccaaaatt tatcatgacc ttttttatct tcaatattaa atgaaatcaa
     3061 ttgttcaatc aattcccagt tgattacact tttccaagga actttgatga cgttatctgt
     3121 atatacgtag cctgcttctt ggatattttt ttcaagggca cgaatcgctg ctttttccgg
     3181 tgcgatagaa aaatgatttt tagcaaaact aaatgcaata ataaaggtac catggtcagt
     3241 aaacataggt tggttccatt ttacagttgt gtctagctgg ggatacgttt ctgttatctt
     3301 agcaaaaagg tctttgatct tttgttgatg ttctttttct ttgatctgat tgatgatcgg
     3361 ctgaaatttt tccattctaa aacgcctcca ttaagtggtt tgatttattt taccagaaaa
     3421 acaatagtta tgtataaaaa acgaacaaaa cacaagtaat gttgtaaccg ctatatttat
     3481 atgataagat gtctcaaata ataaaataga aaagagacat aaaaatgatt gacttggcaa
     3541 agaaattctt acacgaaaat atatattttg agttgtatca tcatcgagcc atttatacaa
     3601 atgaagatgc tttggtaata aagaaagaac aaggatttac aggtacagag accaaaagct
     3661 tattcttaaa agataaaaaa gataataact acgtatatct gacttttact acgaaacaaa
     3721 cggatttcaa agcattgggg aagatcgtcg gtaaaaggct ttctattgtt tcatcagaac
     3781 acatggaaga acaaacggga caaaagcagg gcgctgtttc tccgtttggt tatgaaaaac
     3841 agattccgat tattattgat gaagagctct tattaaatga aaaacttgtt tttgcaccag
     3901 gtagaccaga tcaaacgatg gtcatccaaa cggttgactt aaacaaaatc atccagctac
     3961 ttgagatgcc gatatttttg atgccggcaa acgaaaaaaa caattaacca agtaaaatag
     4021 tgcatacttg gaggtgaagc aacatgataa gttatccatt attagaaaga aatacaacga
     4081 ttggggttac tgcaccatcc tcaggcgtat cagaggaaca ccattcgtta ctcgaatcag
     4141 ctttaaagag aatggaagaa aaatctttcc aagtagttac tggaaagacg ctttggacgc
     4201 aagataagga aaaatcaggt ccagcaagaa aacgagcaga tgaattcaat caaatgatgc
     4261 aagatgaaaa tatccaaatg atctttccgc cttggggagg agaattattg attgagattc
     4321 tcgattttgt cgattttgat gctctacaac caaaatggat agtaggttat tcagatatta
     4381 gtacgttgct acttgctgtc acattaaaaa cagggatagc cactgcacat ggaatcaacc
     4441 ttattgattt aagaggagag tacttggatg aaacgacagc aatgtgggaa agtgtactga
     4501 aaacaagaga aggagaatcg attctacagc aaccttctga aaagtatcaa aaagagtggc
     4561 cccatgagca ttcatcatct tctgttttcc atctcactga accaacaaat tggcaatcag
     4621 tcagcggaga tgcagtaagg atgaagggac gattattagg tggctgtatt gatacgatca
     4681 gtcatttaat cggtacccct tatggagatg tccaatcttt taaaagaaag tataatgatg
     4741 gaaagccgat cttgtggttt ctagaaaatt gtgagctatc gtcagttgat ttaagaagat
     4801 cacttgttca gatgaaactg gcaggatggt ttgatggcag ctcggggatc atgttcggta
     4861 gaagtgcagc agaggatttg ttagattata aaatgaagga tgtatacgaa gatctgtcaa
     4921 aggaattaaa actaccgatc ttgtatgata ttgattgtgg tcatgtaccg ccacaactga
     4981 cattgatcaa tggtgcctat gcagaagtag cggtagaaga tagaaaagcg actgttttgc
     5041 aaacgtttat ttaaaaaatt ttttcctgcc ttggagttta tcaaagacca acaaatctaa
     5101 atagaaaaga aaatgaaaga agctgacagt attttgccag cttctttttg tatgatctat
     5161 tagaaatttt aattatccat aactatcaca ttgatcagct gtttcacatc atttggatta
     5221 cctgtaggaa tagctactac agatgcatta tcaataattt cttgagttgt ttctctaatg
     5281 aacgctggat aagatgtttg atctgcaggc atttgccaat gtgtaggaac tggataacta
     5341 gtgattgtcc cgtcatggtt acttgaatac actaaaactc cctggtaact gtatttccca
     5401 gtgagcataa ccacatcttt cggatagact gcactccctg catcataagg ggcgataggt
     5461 gttcctgcag gataatgaat aacatgtagt tcgaaatcac tcgatgtatc tctaaaagta
     5521 ttacctctaa tagctagcca aacacgtgcg tactcaattt gtagatcaga atatcctgct
     5581 aacggatcta ttgactgaga agactgtgag gaagttgtgt ctattgttga agaagaaata
     5641 tttgtctcaa ctgtactact agatgtagaa gaagtattgg gctctgagac tttactgctt
     5701 gttgaagatg tattcgtttc agtagaagct gatttctgag tacttgattt ttcagctgaa
     5761 ctggtttgtc tgattgaact tttgtctgtg gtcgcagatg gatcactatt ttctttacta
     5821 ggagacgtac atcctacaag gaataaagag accaacaata aaataaaacc taactttttc
     5881 atataaaata cctcattatt tttttaatac cagtatagcg taatcctgaa tttttgaatc
     5941 cgtaaaacct tgtctatgaa tataaataga gtatatcttc tttgataaat gtcagaaaaa
     6001 gtgtgacaaa taaccatcag taaaattact tgtcatacta ttgagaagga gtatttaatt
     6061 gaagagaatg attaggagaa aggatctccg tactttttat agtaatcata gaatccaagt
     6121 ttgtatagac gaatcgtttt ttctcttatt tcttctgttt caaaatggac tgcttgaaga
     6181 atcaagtctg tgaattctat aggagctgtt ccattcgcag taatcaaatt acgatctttc
     6241 acagcttgtt gttctataaa atcttcttta ttctgataat tttccgattc taaccaagga
     6301 aattgcgcat ttccggtgtg tttgtaacct tgcaataatc cgctctgagc taaataatca
     6361 actgccccac aaatagcagc tactggtacg tctgttttta acaatttatc gattatttga
     6421 tataaatgat gattttttat gtcccatgaa ttgccaccga tcataataaa aaggtcaact
     6481 ttttcaggta tttgttcgat taagtaatcg atttttgttt ttaatcctcc aatggaagtg
     6541 acctctgatt ggatagaagc agttttgttt tgccatccct ctttttggtt tagtgtgcta
     6601 gtaatataag caccttccca atcggcatat tcctctaata gaaacgtaat cgcagttttc
     6661 attttcaagc tctcctttac tatctatgac aaggacaaca gttttaacat acagacattc
     6721 attaaatttg gatagcgaca gcgaaaacaa caattcttaa gttttagaca gagtatacag
     6781 acagtcaact taattaaata cgaactaaat aaaaatgaca ggtaatcatt tttgtttacc
     6841 agcattataa cattttgcat acatggatga caaaagaacc aattcccact tgcttgagta
     6901 caatcttaaa agaaactgga aggcaaaaag taattataga aacgaaaaat aaatcatatc
     6961 gggcactcag acatgaaaac aaccctagaa atatataact agtccaatga aaaaacagcg
     7021 aatgccgtag aaaacaagga ttctgcgtac attcatatct cattttgcga gcatatctgc
     7081 tattactgtg actaaatgtt aatatggtta aaatgaccgt tatatttttt atataaatat
     7141 cgtataatta gtatgaatat agaagaagga aagaaggtgc aatcttggaa cctaaagaca
     7201 agtatttaga ttacgctagg gtcaataaag ataaatttat tgaaacaatc atcaagggaa
     7261 aaatccctga tgatgaaaaa gatgcggtat tcatggctgg aagcccagga gcaggtaaaa
     7321 cagaggttgc actaggttta gctgaaaatt atgacaacca tgttgtgatt gatgcggact
     7381 attttagagc acaatttcca gaatacaatg gaaagaactc aagtgttttt cagaaagctt
     7441 cttcttggtt agttgaacaa tcattaaaat atgtactgga acatggctat tctttcatac
     7501 tagaggatac ttttgctatc cttagtgcag agaaaaatat tattcgagcc cttaaaaata
     7561 actttcgcgt tacgattttc tatgtttacc aagatcccaa agttgcctgg gatttcactc
     7621 gaaaacgtga actagctgaa ggacgtcatg tgccaaaaga aatgtttatc aatgcgtttt
     7681 ttaagtccag agagaatatt gaaaaagtca aaaatagaca tcctgaagta gtccttcaca
     7741 taatgattaa ggattatcaa aacgacattt ctgaagtgca ttatgcagca gataatattc
     7801 aattagtact acccaataca atatacttca aaagagttgg aggaggaatt acatgactga
     7861 gaaagaacaa gtacaacaaa tcgtgaagaa gtataataaa agtatcgctg atttatcaga
     7921 aaacgcctca gcgaaagaat ttaaaacagt aatgaagtac gtagcagatg aagcaaatcg
     7981 taagcagcga aaactagttg ggttggataa ataaattttt taaaccatat ccttgtaaag
     8041 ttgagttttt tgttttaatg aattaagact attaaataga taattattgt aacttaaaaa
     8101 acacagctaa aaattagttg tgttttttat taggtttact tttctggtat aaaaggaact
     8161 agctactttt tcaaaatttc taaatcattc aatatgtagc gcttactaaa ttattcgcca
     8221 taaaatttta taattggatc actcattgtt ttacctaagt catatttaag taataaccgg
     8281 tgtttttaca taagaagact tggggtattt tttagtttga ttagctctga tatacctata
     8341 aagaatatgc taaggtaaga atagtaaaaa ttcacataga tgaggtataa taatgatgtt
     8401 tttatatatt acagataact tgacacaaaa tgagtttttt tcgatttttc aagttatcta
     8461 atgcaattat attgatatca ttaggagctg cattgttatg aatccaacat tgattactaa
     8521 gaaagaatta ctaaaaaaat tagatatttc tactggtgta ttagctgatt taattagaaa
     8581 tggcatgcca aaagagggag aaatgtttaa tcttgataag attattacat ggcgagaaaa
     8641 ttggtctaaa aacatattag gtgagttaga agttggtaga gtatatacta acaaagaaat
     8701 ttcagagaag tttaaatgtt tcaaacaggg tggaatgaga agatctcatc aaactaatac
     8761 tcttgtactg tttagtgatc aaacaggaag taatgtttat aaagataagt ggttaaatgg
     8821 tattttacaa tataccggta tggggctaaa aggggatcaa gtattggata agaatcaaaa
     8881 taaagtttta gccaattcaa aaagtaattt tgtaaagatt catttatttg aaacatttaa
     8941 accaaaagaa cacacgtatc tgggagaagt atatttagca ggacaaatat atactgttaa
     9001 tgaaaaagat agttcgggca acagcagaaa agtatataaa tttccattag ctttaataaa
     9061 tcaagagcaa ttgattgaag ataaagatat atataaccag gaagaaaatc aaactagaca
     9121 tattcgtaat ttatctgatg ctaaattaga ggaagaagca agaaaagtta gtaattataa
     9181 taaaaaaatg gctgcaaaat atgttaacga agaggagttt tgcttctcaa aaacaaaaat
     9241 atataaacgt acccgtggtg ctagttaatt ttaatatcct aaagaatatc tcaaagttcc
     9301 ttcaaaacgt cgttgtgctc gacttaat
//
LOCUS       DACBZK010000084         9209 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.087, whole genome shotgun sequence.
ACCESSION   DACBZK010000084 DACBZK010000000
VERSION     DACBZK010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9209
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.087"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            470..2107
                     /locus_tag="IVD66_002355"
     CDS             470..2107
                     /locus_tag="IVD66_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAP6146545.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(2252..2992)
                     /gene="truA"
                     /locus_tag="IVD66_002356"
     CDS             complement(2252..2992)
                     /gene="truA"
                     /locus_tag="IVD66_002356"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAP6146546.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(3183..3818)
                     /locus_tag="IVD66_002357"
     CDS             complement(3183..3818)
                     /locus_tag="IVD66_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAP6146547.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3965..5206)
                     /gene="sstT"
                     /locus_tag="IVD66_002358"
     CDS             complement(3965..5206)
                     /gene="sstT"
                     /locus_tag="IVD66_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HAP6146548.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            5404..6400
                     /locus_tag="IVD66_002359"
                     /pseudo
     CDS             5404..6400
                     /locus_tag="IVD66_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6416..8434
                     /locus_tag="IVD66_002360"
     CDS             6416..8434
                     /locus_tag="IVD66_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HAP6146549.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(8494..9186)
                     /locus_tag="IVD66_002361"
     CDS             complement(8494..9186)
                     /locus_tag="IVD66_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAP6146550.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT         2978 a         1706 c         1445 g         3080 t
ORIGIN      
        1 actaatcaga atcgtacaaa tatttaataa ccaaatatat agaacataac ttaatattaa
       61 gttatttgaa attccataaa aaacgactgc aggaattatt gtaagaaaag gataaaaata
      121 gttcagtcca tctccataat tgttaaatgt tgtatagttg attggccctt caaaaataga
      181 agataaccct ttgattcgtg aaagatgaaa agataaatca cctgttgtat aaatttcttg
      241 agcatttctc ataaaattta ctgaatataa agtactaagt aagataagaa ctactaaaag
      301 aaatgctttt ttacttattt tcatagattt gttgttctcc ttttttaatt ctattttcag
      361 tatactagaa ttgtcttttt ttaataagtt ttgcgttaaa tttttcatag cactagtatg
      421 atatactaga aaagaatcaa tttttattac ttttaaatag gagaaaaaaa tgaaaaaaaa
      481 caaaaaccaa ataatagata tcatttttat gttatttcta agttttgctt acgtcatccc
      541 tctattcatg tctatgggaa tctatcatag tgtcaatcag gatacttact ttcatttatc
      601 tcgaatcata ggactagata atgtatggag ttctccagta aacttcaata acttcgatca
      661 tcatggaaca atgatgaata ttttttatcc atggcttact ctttatccag cttttttatt
      721 ttataaaatg atgggaaatc ttgttttaag ttataatatc tactattttt ttatcacttt
      781 tttaacaatg gtcgtttctt atttttctat gaaacaaata aaaaacaatc gttatatttc
      841 gctgttattt tcgattattt atacattttc cgcctatcgt gccattgaca tattccatcg
      901 tgcttcattg ggagaagctg tcgctttaac atttttgcct ttgatactaa tggggtgtta
      961 cgaaatttat attagagatt accaaaaatg gtactggttg tctattggca tgacgctagt
     1021 agtgtatact catttacttt ctgtcgctat ggtttctgta tttattggag gaacgttgtt
     1081 tctttctttt tatttttggg accaaaaaat cgctagactc ttaagtcttt taaaagctac
     1141 cgtcctcacc ttttttttaa gtgcgggatt cttaattcct tttattcaac aatctagagc
     1201 acaagaattg aaagtcccac tgggaaaaga attaagtggt atggctccta gtgatatgct
     1261 gacacacatt ttaaataata actataacaa ctatactatt ggattattct tatttctcgg
     1321 attgattggt gcttttattt ttataaaaaa attaactgct gatgatttat ttattttctt
     1381 tcttggtgta tttgttcttt tttgttcaac caatttattt ccttggcaac tttttaacca
     1441 tacaccagtt aagagtctac aatttgtctg gcggttaaat ggtttttctt ctttatttat
     1501 agcctatacg atgagtatag tgatctatta tattttttct actaaaaata attcatggaa
     1561 aataatggtc tttacgtttc ttgcactaat attgcatctc tcaggagtaa gcaattctat
     1621 ccatgctaac aaagattcat taacacttat agcacctgaa gacgctgttg ctatagctga
     1681 aaattacaat catactgatt atgcaaacaa agagtcaatc tatcatcctg atatgattaa
     1741 taatgatcaa tatttactag gtaaccagga aataaatcca acaactcatt ttatgagtaa
     1801 caaacttaca attgaattag ataattcgaa taataaaaat actgtcttga cgacacctat
     1861 ttatcgttat aaagggcaag tggcttctat taatggcaaa ctagtacaaa caaaattatc
     1921 taagtttggc acaactgaat taactattcc tccaggtata aataaagtcg ttattactta
     1981 tcagtacaca aaactagcaa ttgcttcaag atatttatct atcgttactt tgattttatt
     2041 tttactttat cgatttactt tttctaaaca aaaacaaccg agaagagaag tacaacattc
     2101 tcactagatt tttatttaag aaagactttt tagctgtaca cataaacagg ctaaaaagtc
     2161 tttttttata tttctttaat ttgcttcata cattatttaa catcgatatt tatactgtga
     2221 aacatgcgtt tcatccatta tcaaagtatt tttatcgata ataaacttca tccaaaaaca
     2281 gaccttgtgc agggacggtt tctcctgcat gttgccgcac tttgctttca aatatttcat
     2341 cgattgtttc tatcggcatg gcacctgtgc cgatttctag taatgtcccc atgataatcc
     2401 gcaccatttt atataagaat ccgtctccga caaaagtaaa atgaagcatt tctccctttc
     2461 gttcgataga taattcatca atcgtacgca ctgtggattt ttttgatttt ttcaatgcag
     2521 aaaaaccaat gaaatcatgt gtacccacta atttttcgca agctgcattc agcttgtcca
     2581 tatccaactc ttgagggaaa taaaagctgt ggtttcgctc aaatgctgaa ggaatcacgt
     2641 tgttccaaac ataatagctg tattttttgc ccaccgcatt atatcttgaa tggaagcgct
     2701 caggcatttc ttcgattctt ttgatgacaa tatcccgcgg aaggtaacga ttcataaagt
     2761 cgatcatttc tgccagtcca atttctgtgt ttgttttaaa atttgctact tgtcctcgcg
     2821 catgggtgcc agcatctgtt cttcctgatc caataatttc tatctcttca tttgtcatct
     2881 gatgcaatac tttttcgatt tttccttgaa tggttttatc gtcatctcca agtctttgcc
     2941 atcctgaata tctttttccg tcatattcga ttgtcaactt gatgtttctc atattttagt
     3001 ggctcctctg tcttccattt ggtcttctct ctaccttttt aagattgtag cacaaaatat
     3061 agctcctttc ttctctaaaa cagaagctat acaagaaaac tgtggaaata tatatttcag
     3121 aaaaacaaaa aacagccacc ggatgaagta tccgctgact gttcaatttg acggctcaag
     3181 ttttactgtt tgagatgcaa gatactcaac caggcaatgg gcacataatt aaagaaaaaa
     3241 ctgattcttt ggcaaaaacc tattttattc agtaatggcc aagaatttat agaaggaatt
     3301 cttgccagtc cataaatcgc cgcaaaaagc aaactgatca cagacagtcc aaggtataag
     3361 tggcttacgt ccatttgccc attttttcga tagatcaaga aaagaagaac tggaaacaat
     3421 aaaaaaccac tgtaacctaa acctgatccg atattatgga cccatgtcga gacattccac
     3481 gaagattcat gggtattgat actgaacaaa cctgtaaaga tacaatcacc tataccatag
     3541 aacgcgatgg ctgctgtaac tagggtagct aacacacgag atgtacttac aaatgcagca
     3601 tacaatgcag gcaatgacag gatgaaaaag atccctgaaa ccacagacca aataagaaac
     3661 gcttttctta caggactgga aacctctcca aatacactga tcacgctctt catttgatct
     3721 aattcaggat aatacaatcc taatacgtac ggagtcaaaa aatcactcag cacgcctaat
     3781 aataaaaaga aaaaaccaaa tttacgtaaa aaatccatga tacgcctcca ataacaatta
     3841 cctatgcttt taattgttat tataaacgac tttatcttga tttaacagaa acctctattt
     3901 acacgaacat ctatataact cattaaaaac tcgaatcatt ttaaaaatac taaatatcta
     3961 acgttcaacg ttcacttaat ccatctaaac aatctttcaa tttgattttt tccccacttc
     4021 ttttacgcgc gcctagctct cctattgcag taaacaacag atcacttgac gaatttaagg
     4081 cagtttccat tgaatcctgg ataacaccga taataaatcc aataccgacg atttgcatcg
     4141 cgacatcatt agagatacca aacaaactac atgctaatgg aatcaataac agtgaaccgc
     4201 ccgcaacacc tgaagctcca caagcagcta aagcagacaa aatacataaa aggactttca
     4261 aaacaaaagg tgcttcaatc cctaaagaat gtacagcagt caacgtcatc aaggaaatgg
     4321 taatcgcggc accgcccata ttgatcgtag cacctaacgg gatcgatatg gaataagact
     4381 cttttgtcaa tttcaatctt tcagccaaca tcatgtttat cgggatattt gcggcagaac
     4441 ttcgggtaaa gaaagcggga agtgcgcttt ctttcaaaca aaagaaaatc aatggatagg
     4501 gattttcttt aataaacaaa aacgtgagga atgggtacac aactaatgcg acaaacagca
     4561 tcgtaccgat caaaacaagt aaaagctgca gatactctgc caatccagcg attccagtcg
     4621 tagcaattga ttgataaacc aatcctaaaa tccctatcgg agcaaatgca ataatcactt
     4681 gtacgacttg tgacaacgct atagatatct gatccaccaa ctcttttgtc gattctgaac
     4741 gtgctcgaaa agctagtccc aacaatacag cccagaataa gacgccaagg taattcgcat
     4801 caataagaga ttgaacagga ttttgtgtga cattcgtcaa catagtagat aaaacacttt
     4861 ccaaactttg cggtgctttt tcagatactg tttcttgtaa agtaatagga acagtaaaaa
     4921 ttgaacttac aataactgct acaagtgcag aaagcaatgt tcccactaaa tataagatca
     4981 aaataggctt cacgaatgtc ttattcccaa ttttatgctt ggcaattgac gccatcgtca
     5041 agaaaaaaac cagaataggt gcgattgcct tcaagcaact gacaaacaac gttcccaata
     5101 ttgaaataaa tgtccatgtg gggaaaaaga taccaaacaa tattccgact aaaataccaa
     5161 caacaatacg ttgaactaac gacatatcca aaaacttctc taacaaatga ccaccctttc
     5221 acaattttaa caatcattgt atcattttat gcaaagaaac taaaggtata attttctaaa
     5281 aattctaaca atacaaacaa ccatttcttg ctaattttgt actttttctg tctacacgtt
     5341 gttttttgag atattctaag ttaggatgtt attaatgggc aacttatcag gaaacgtttt
     5401 cttatgtttt tgtccaattt ttttgtgagg tgtttattct tgaaaaaaat aaagaaggag
     5461 agttatggct tcctgacaat ctttgtcgct tgtataatga tggttttaca gcgtatattg
     5521 atttcagcag tcactattcc tacatatgca acaaaccctg gtcgattcta catctataca
     5581 tttttacaaa cttccgttgt tattggtgca aatttgatcc cactttacat gggttaccaa
     5641 tatcaaaaaa tcgcccgttt aaaagtttta cattatttaa gtcgttttgc ctttatattc
     5701 ctaatagcca cactagtttg caatatcttt tttttacgta caagctggca gcttgaatat
     5761 tcgtgattat tggcttatcc taacacctat cagtcagaat tactttactt atgctgtttc
     5821 ttgtactttg cttttttgta gtattcctta tacagttgga tttttaaata aattatcgaa
     5881 aacaacaatt aaatatctac tattattttt aacaattgga ttagttggct gctctactct
     5941 atttaataaa gacccgtttg cattacagaa tggacagagt attttatgga ttttttattt
     6001 atttttaatg ggttatggtt tgaaagaatg gaactggaaa gaaaaggtcc gctataagct
     6061 tcctcaagta tttatcagct tgattgtttt attcggtttg attattttga tgacacaaat
     6121 ttcactcatc atcagaggaa atacagatac agcgctgagg ttttctaaac catattctct
     6181 cttcgcaatg tattatactt tctcttcgtt tttattttta gaaatgctat ctgataaatt
     6241 aggtataaaa ggaagaggaa attttcttgc tgtatttttg attgtcactc aagttatatg
     6301 taatttccct ttagtttctt atcgcgtatc tacatttatg aaacgtgaat ttccaaactc
     6361 agggaaggca tggctgataa atatcgggca gttttttatt tgctatttat tagcagtgtc
     6421 cctcctagtt atctttttat tttatataca aaaaatccgt ttcattcatc gtttcatcga
     6481 atacttcgct tttgattcga ttgaacaatt aactcagcgt tggaaaaaaa gaattcattg
     6541 gctttttgtt cataaaagtt attttttagt tgcagcattt ttttactgct ttaccttcgt
     6601 gcagattttc gttttagaac caaaagaagg ttggaaagaa actatccagg ttgccttaaa
     6661 aatatttact cagcgacaag cacccatgat cctgacaatc atcattatta tgggattttt
     6721 cttcttacta ttgttgattt ccaatcgttt ttggtacgcc ttgactgcta ccttgatcat
     6781 taacttactg ctcactattt cgacagtaat caaaatggaa atgcgggaag agcctgtctt
     6841 tccttcagat ttaaaaatgc tgaccggatt gtcagaacta ttatcgatgg ttagcccagt
     6901 cttattaatc gtgggcggat tgatccttct cctattattg attactagta ttattgtaca
     6961 acgtagacta caaaaacagt attccttgaa gattcattgg aaacgtcgat ttatcagtat
     7021 cgctgtatta ttaggatgtt tttcgggtgt ctttttcatt aatcacaaaa attcgccttc
     7081 tttcttgctg tttaatttat ttaaagtaaa caagactttc tttaaccagc aaggcgccgt
     7141 aaaagataac ggaccagtca ttcaattcct aaacaatatc gacattaaaa tcatggaaga
     7201 acctgctggc tattcgaaag aaaaaattaa tggaataatg aaaaagtaca acacaaaggc
     7261 agatgaaatc aaccaaacaa gaagtgactg gttaaacaat cagacgatcg ttctcaattt
     7321 aagtgaaagc ttcagtgatc ctgcacgtgt ccctaatctg acagtaccta cagaccctat
     7381 tccttacatc aaaagcatta taacagaagg aacaggagga ttgatgttat ccgtcggtta
     7441 tggtggcgga acagctaaca tggaatggga aggactgaca ggcttgagta tcagtaacct
     7501 gtctgcttcg ttagttacac cttataccca gctagtggag cgtcagaaaa taagtccaaa
     7561 tattaccgat ctattcgatg aaaaaatagc catccatcct tttacagctg ctctttatcg
     7621 cagaaaacaa gtgtttgata aatttggttt tgacaggttc tattatttag acagtccgga
     7681 taaattaact tatacggata aaatagaaca aagcccacgc atatcggatg attcagcata
     7741 caaagaaacc ttgaaagctt tacaaagcaa tacagaaacg tcacaattca tccaattatc
     7801 cactatgcaa aaccatatgc cttatgatga ttactatagt gaattgaact acactgctga
     7861 aggaactgct gtcattccta atagaagaaa agaattacaa acttatatgc aaggccttca
     7921 ctataccgat acagcagtaa aaaaattcat ccaagaaatc gacaaaatcg ataaaccgat
     7981 tacctttgtt ttttatggtg accatttacc cgcaatctat agtgggaatg attcgaaaaa
     8041 atatggatta gaacagcacc agacagatta tttcatttat aacaacaagt atagtcgtga
     8101 acaagcagct acgttaaata aagaagttgt tgctcctaat aactttggtg ctatggctct
     8161 tgagcatgcg aatatcaaag taactcctta ctatgcgttg ttgacagaag tatctaatca
     8221 tctacctgca ttaacaattg atcctacaga aagcttgtct aatcgtttta atggaaaaca
     8281 ggtctttgtt acagaggata gtcaaattat ccaagaaaaa aatttaactg agaaacaaaa
     8341 agaaattcta gaagattatc gtctgataca atatgatctt gttgcaggta accagtacag
     8401 tgcaacatgg gcgacacaaa aaataaaaga ctaacaaata aactgagcaa ggggttgtga
     8461 taaaagacat gtcacaaccc cttgtttatc tcattaattt gcttgtccat aaacgatttg
     8521 attaaagcca tttttcaatt cattattcgc tgtctcgttg aagtaaagat aattatcggg
     8581 attcccctga ttttgttgtg tcaccaatac ttttggctga ttttgctgaa acccgaatag
     8641 atagacgtgc tttttcagat atggttctgt ctctgcatcg gaatagacgg ctgtgatttg
     8701 atagtctgct tgacctgtcc cactttctga ccattctgca gaaacaggca ctccaccaat
     8761 agccatcttc cactccccgt tcaaaatagc ttgagggact ttaagaccat ataagtccac
     8821 actcatttga ttcgtataac ttttgtattg ttgtcccatt gtttggcccc atttggtcat
     8881 aaatgcctct aattgtgcgg atttgtctgc attccacagt gtttgttcaa cttgttcgct
     8941 gctttctgaa gaggaagatg aagcctctac agaagaactt gaagtagatg tttgagttgt
     9001 ttcagtcgtt ttggaagact ctgacgaagt agaggtatct gctgtttctg tacttgctgc
     9061 agttgacttg ctctctgtgc tagttgttgt agtagttgca actgttgctt tcgctgtttc
     9121 ttttgttgat tcttttttcg attcattccc gttggtacaa ccagctaaca aaaaagctag
     9181 accaattgtt actaaaatcc tttttttca
//
LOCUS       DACBZK010000085         8942 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.088, whole genome shotgun sequence.
ACCESSION   DACBZK010000085 DACBZK010000000
VERSION     DACBZK010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8942
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.088"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            51..260
                     /locus_tag="IVD66_002362"
     CDS             51..260
                     /locus_tag="IVD66_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146551.1"
                     /translation="MICYISFLILGLPQAVFPEMFSGDWGIVSYSILTLIAMVLGTSF
                     YNAFVSKHVEEYEVLMYLKEKKTSN"
     gene            467..667
                     /locus_tag="IVD66_002363"
                     /pseudo
     CDS             467..667
                     /locus_tag="IVD66_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1379..1984)
                     /locus_tag="IVD66_002364"
     CDS             complement(1379..1984)
                     /locus_tag="IVD66_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6146552.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
     gene            2166..2501
                     /locus_tag="IVD66_002365"
                     /pseudo
     CDS             2166..2501
                     /locus_tag="IVD66_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2666..2893
                     /locus_tag="IVD66_002366"
                     /pseudo
     CDS             2666..2893
                     /locus_tag="IVD66_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            3019..3990
                     /locus_tag="IVD66_002367"
     CDS             3019..3990
                     /locus_tag="IVD66_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6146553.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            4130..5443
                     /locus_tag="IVD66_002368"
     CDS             4130..5443
                     /locus_tag="IVD66_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP6146554.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            5486..6352
                     /locus_tag="IVD66_002369"
     CDS             5486..6352
                     /locus_tag="IVD66_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6146555.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            6349..7197
                     /locus_tag="IVD66_002370"
     CDS             6349..7197
                     /locus_tag="IVD66_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006639650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6146556.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            7211..8683
                     /locus_tag="IVD66_002371"
     CDS             7211..8683
                     /locus_tag="IVD66_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAP6146557.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            8700..>8942
                     /locus_tag="IVD66_002372"
     CDS             8700..>8942
                     /locus_tag="IVD66_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP6146558.1"
                     /translation="MIYGSIEAGGTKFVCAISDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPK"
BASE COUNT         2830 a         1515 c         1831 g         2766 t
ORIGIN      
        1 atttaaaaag aaaagtgaca gataggaata aaaacttatt aaatgtagtt atgatctgtt
       61 atatttcatt tctaatacta ggtcttccac aagcagtgtt tcctgaaatg ttttctggag
      121 actggggtat tgtcagctat tctatattaa cattgattgc tatggtttta ggtacttcat
      181 tttataatgc ttttgtaagt aagcatgttg aggaatatga agtattaatg tacttaaaag
      241 agaaaaaaac aagtaattaa tatgagaaca ccacgcatag tttttatttt gagatattct
      301 agaatgaaac acattaagaa cgaaagcaaa gcaaaagacg ccagaacttc tactaccttc
      361 taagtttttt catatttgtt tgttatgcta tacatagatc tgcataatta gacttgcgct
      421 gcccgttatt gaagtttcag gcagcgctct ttttggggga tcgataatgg aagaagaaaa
      481 aatatttgag aaacgctggc agctagcatc aagtgaacaa agagcaagat acaataattt
      541 gatcacctcc taccccactg ttgactagac atataaggaa aagaaatact tactttggct
      601 gtgccagtta gatatagata cctttgaaac atttgaagtg atcctagata aaattaaaca
      661 gaattgatca gaaacaagcg aagccttctc tcggttcgct tgttttgcta tttattagtt
      721 ggctcagggc aactctaagc tcgtttgaaa gaaaaccgat ggataatccc cttgtttgta
      781 ccactttaga atacatggat gtacgtattg ccattgactc ctattagtta ctgaaaaaaa
      841 atttaaacaa gttgagtatt gcagataaat agctccagtg aggtgaataa ctgctccact
      901 caaggcaata gatagctcca tccagggcaa caaactgctc cactttcata tttaatagat
      961 gaataacctt ctgtataata gaaaggcata cctttcggta tgacaactta tacagaatgt
     1021 tattttattg gttcactatc gaaaaatttt ggagctttat ttttccggta tttctcaacg
     1081 aacgattagt ttaactgtgg gaagctccag acatacgatt cgagaagtta cttctcgagc
     1141 agacaggaag ggggtgactg aactaaccgc tgatatgagc gatacttggc tgtaggaata
     1201 tctttttccg gaaaaacaaa caacagcacg aggttacctt cctgtagact gggaatatgt
     1261 tcataaagaa ctaatgaaaa agaatatgac attgaaactc cttcatagag aatatggggt
     1321 acatggaaca tagaaacgaa aatgcacggt agaaaagcga atgaatatag tataaattct
     1381 acaaatcatt cgctttcttt attttatata tggttggtcg agagagacca ttttctttgg
     1441 caatttctgc aactggaact ccttgattta acatgtccac cacagtttta aagactaatc
     1501 gtttttgcgg atctgttgag ttctcagaat attcaattgg tcgcccctta tatcgaccag
     1561 cttttttggc caataatact ccttgccgct gacgttcacg gattttctca cgttcgtttt
     1621 gtgcaatata acttagcaat gataaaaaca tatcgaacat agcagtatct aggagttcat
     1681 ttccagtatt aaaatctaaa aactgtgcat ctagtatttt taatgctact tttttctgtt
     1741 tcataaaggt aactgtattt tttatgtctt cataatctct gcctaggcga tccagtgatg
     1801 caacaatgac acaatcacct tctcggatat aatttagtaa tttttgaaac tcaggtcgct
     1861 ggatatcttt accactggct ttttcttgga ataatttatc aatgttaagg tcttccatca
     1921 ttgccaattg tcgatctaaa ttttgatctt gtgaagacac tctaatatat ccaatttttg
     1981 ccataaaaac tccttttaaa aaatgatata atttacatgt aaaatttact tgtagtttta
     2041 ctgttatcat agcattttta aaaataaatt ttaagtctac ttataattta ctttggaggt
     2101 tttgaatgaa tgaaattaag cgcaataaaa attcttttgg tgtttattta ggagagccta
     2161 gctcggaaca gttaaataaa ggtgaagctc gtcatgctct atgtcgaaat atattttatg
     2221 gtagaaaagg caaactttat caaacttatt acgacggtat ggaggaacag ctcaacgcat
     2281 taggattagt aactaatgct atcatatatt ggaattcact atatttagaa aaagtctttg
     2341 aacaaattaa aacggaaggg ttcgactgtt ccgaagaagt gttacgcaag caatttccat
     2401 taattagtga tcacattaat tttgttggca aatatagttt ccgctatgaa aaagaattat
     2461 cgaatggaat actacgtccg ttaaatatag agaattattg agaatgttcg tcttttggtt
     2521 cctaccgtgc attttcgcac ggatgttcca gatactattt ttgaatgtat aaaattgaaa
     2581 acacaagaat actaataaat caacgattct tgtgttttta atttttcact accgtgcatt
     2641 ttcgtttcta tgttccatgt accccaatct tgaaaaatta attaaagact tagataaagc
     2701 cattgacgac ttagtcgtgg tgctaccgga gtatcaatgt ttaaccagta tcccaggtat
     2761 tggtcctgtt taggctgctg gaatactcgc tgaaattggt ccaattgaac gtttttctga
     2821 tgaaataaaa ttgacaaagt atgccggcct atattggcga cagagtcaat ccggtaaatc
     2881 tgaatacgaa aattttttta cgaaaagctt cacgtctaat atctatttta aaataaaaat
     2941 attcctgcta atttggaatc gtttccttct tttggtataa taatacctga aattcttttg
     3001 agaggagttg ttcgtgaagt gaaaactact atgaaggatg ttgctgcgtt agcaggagtt
     3061 ggtgtgggta cggtatctag agtaataaat ggagtaaagg tgaaagaggt taccaaagaa
     3121 aaagtaatgg ctgcaattag tgagcttaat tatgagcctg atgaatatgc cagaggtatg
     3181 aaaacgaata gtagcaatac aatagctctt attttaccta cgatttggca tcccttcttt
     3241 tccgagtttg cctactatgt agaggaagct ctcagccaaa aaaattataa gctttttttg
     3301 tgtaatgcga acggcagtgc ggaaaaagaa aaagaatata tccaaatggt caagcagagt
     3361 aaagtagacg gaattatagg tattacctat tcagacattg ataaatatgt atcatcaaat
     3421 ttaccatttg tcagtataga ccgccatttt tcggaacagg tttcttatgt aacggcagat
     3481 aattatttag gtgggcaaat tgccgctcaa gaactactta ctcgtaactg taaaaacttg
     3541 tgctatgttg ggggtgtttc accttaccct aacgaaacaa acaatcgtaa agctggtttt
     3601 tacaatattt gtgaggaaaa taaaatagct gtgaaggtat tggatatgcc tgaaccaatt
     3661 agcaatttag aggaacaatt gctcgctttt ttttcggata atcctgaaat tgatagcatt
     3721 tttaccatca atgatttcat ggctttggat gtgataaaag cccaaaaaaa actagggaag
     3781 gaagcaccta aggattttca aattattggt tttgatggag tcaagctatc gttgcaaaaa
     3841 gactatttac tatcaacgat tgtacagccg atagaggaaa tggccaaggt ttcagtagaa
     3901 acactcatgg cgatgatttt aaatgaagaa ccgcctaagc gtgtggtagt accggttttc
     3961 tttcacgctg gagagacgac taaagagtaa aaaaccggtt tataacgatt tttttgagat
     4021 aggttgacag aaagtgattt caatgatatc ttaaaaccaa ttaattggaa acgttaccaa
     4081 ttaattgaaa aataaaacgg aaacgtttca aaaaatagga ggaacatcga tgaaaaagag
     4141 aatgttagca attgcagcaa ttttagcatt aacagctgga ggacttgcag gatgtggcag
     4201 taaggagaaa agttcaggta gcagtgatcc aggagaaatt aagatttggg ttcagttttc
     4261 tgatgaaacg cctgaaggaa aagcttgggc agagattgtg aacaatttta atgatgaata
     4321 cgagggtgaa tataaagctg ttactgagta tattcctcgt agcggaagcg gcggtggata
     4381 tgaggataaa gtaaatgctg caattacaac caataccctt cctgatgtta ttacgttaga
     4441 tggaccgaat actgcagctt atgctcattc aggagtcatt gctccattag atgattattt
     4501 gaaagatgcg gacatggatg atgtattaga cagcattatt cagcaaggaa cctacgatgg
     4561 caaaatgtat gcgtttggtt tctcagagtc cagtgtgggt gtctattaca ataagtcgct
     4621 gttcaaagat gctggaatta cagaagatca attgccgacg ttagaagatc cttggacttg
     4681 gacggaattt caagcaattt gccaaaagct gactgataaa tacaaaacgc ctgcaattga
     4741 tatgcaaatg gcgtcgggag acgaaatgct gacctacgca tatacaccat ttatatggtc
     4801 gaatggcggc gatgtcgtta atgctgatgg aaccaaagcc gaagactatt ttaacggtaa
     4861 aaaatccgtt gaagcgttgg aatttattca agaattggtt gaaaaaggtt acaccacaat
     4921 cagtcctatt gaaaaaggat ttgaaactgg caaatatgcc atgatgctga gcggttcttg
     4981 gacaatggca gatttagagg aaaactatca agagattgat tatggtattt tgccttaccc
     5041 cgtttcagat gcaactgggg agttagtttc accaaccgga agctggcagt tagcaatgac
     5101 tgagaaaaca gagaaaaagg atgcttctgc ggcctttatt aagtttgcaa ccagtacaga
     5161 atctagtcgt attatgagtt tagggaacag tgttctacct atcagaaatt caacagttga
     5221 tttaattaaa gatgaagtgt cggaaggaat gcaggtatta attaagcaaa accaactttc
     5281 tggacatgcc cgcccagtgg ttgtagctta tccgcaagta tctagagcat tccaacaagc
     5341 agttcaagat attagctact tcgaggaaaa cccagatgta caaaaagtag cagatagtcg
     5401 cgctgctgaa atgcaacagg caattgatac ttcactaaaa tagaagtttc taaagggggc
     5461 caatcaagtg ttaaaaaaac cgacaatgaa agacaatttg ataggttacg gctttctagc
     5521 gccagctttg ctgctgctga cgatttttct gatcataccc gtaatcatgg taatttatta
     5581 tgcctttact gattattatt tgttaacgcc agatgctaga caatttatcg gcttagaaaa
     5641 ttttaagcga ctgttcgctg atccaatttt tgtaaaaagt atttggaaca cggctaaatt
     5701 tgttgtttgg attattccgg tccaaatagg ggcagcttta ggaatggcac ttattatcaa
     5761 caaaaatcgt aaaggaaata tcttttttaa agtagccttt tttgcgccag tcgtgatgtc
     5821 cttagtcgtt atttcgattt tatggttgta cttgttaaat cctaatgaag gtctggttaa
     5881 tacgctattt gcaaagattg gaattgcttc gcagcctttt ttgactagtc ccaaacaagc
     5941 aatgtatacg cttgttttcg tatcggcatg gcaaggtgca ggatatcaga tgctgctgtt
     6001 tttaggggga atgcaaaata ttccgcaaga cgtttatgag gcagccgaaa ttgatggttt
     6061 ttctaagttt cagcaatttc gctatatcac catgccatta ttaaagccca cggcgatttt
     6121 tattttactt accacattga tttcggcctt taaactaatc attcagccaa tggtaatgac
     6181 tcaaggtgga ccaatgaatt ctactatgac aatggtttat tacatttacc aaactggatt
     6241 tacagaccgt atggtaggct actccagctc cattgcgtta atctttacca ctatgattgg
     6301 tttaattaca attgctcaaa gaaaattggt aaaggaggat gatccagcat gaccaagaaa
     6361 tttggaccgc taatgatcgt agaatattgt ttgctgttcc ttttagcggc attattcatt
     6421 ttcccgatgc tgtggatggt agtttcctct atgaagcctg aagcagatgt ctatcaaaat
     6481 ttagcttcct tcaaagcttt tttacctagt ttgaatccag ctaattggtt taaaacttat
     6541 caagaggtta tttcccggtt cagtgtggga acttatttat taaacagtat tttttatggt
     6601 ttaacctttg cctgtgggtc aatcattgta aactctttgg cgggttttgc ctttgcgaag
     6661 gttaattttt caggcaagaa aattatcttt ggagctttgt tagctctgct gattgtcccg
     6721 atggagacgg ttttaattcc gcaatttacc atcgttaatt cactaggctt agtgaatact
     6781 cgcttggcag tgattttacc agcgatggcc agcgcgttta atatctatct gtttagaaat
     6841 ttctttatcg cgattccaga agaaatcatt gaatcagcga aattagatgg tgcaaatatt
     6901 gttaaaattt tctttcacat catgctgcca atgtctaaac cagccatagc cacagtaggt
     6961 gtcttatcct ttatctccag ctggaatgat tatatttggc cgttaatggt cttaactgac
     7021 agcagcaaat tttcaatgca agtggcaatt actacgatca atactacaca gccagtttat
     7081 atcaatcaag tgatggctgt tttaaccatt gcaacgattc cactgattat tgtttatatc
     7141 gttgcacaaa aatatattct gcagggactt ggcggttctg gaacgggtat aaaataggag
     7201 tgaatagtga atgttgcaaa aacttttaaa ggccaatgag tttattgaga aaaatgctca
     7261 aacagtcaat caagaatacc ggaataaatt tcatttgatg gctccgattg gctggatgaa
     7321 tgatccaaat ggttttgttt attatcaaga ggagtatcac ttgttttatc aatattatcc
     7381 ttacgacagc atctggggac caatgcattg gggccatgct aaaagcaagg atctaattca
     7441 ctgggagcat ttgccagtag cactggcacc aggtgaaagc tatgacaagg aaggctgttt
     7501 ttccggcagt gccatagaaa aggatggcaa gctgtatttg atttatacag gacacaatgt
     7561 tgtggaaggg caagttcgac aagttcagtg tttggcagtt tcagaagatg gcattcactt
     7621 tgaaaaatat gccggaaatc caatcatcgc agaagatcac ttagcttctg ttgcaacgac
     7681 cgaagatttc cgcgatccca aagtgtttca gcgaaaagaa gactatttta ctgtagtcgc
     7741 tactaaaact gcagatgctc gtggacaaat tgtgatgttc cattccaaag atttactaac
     7801 ttgggagttt tattccgtat tgctggaggg aactccagaa caaggcattg tatgggaatg
     7861 cccagacttg tttgaactag atggcaaaga agtcttgatt ctttctccta ttcaaatgac
     7921 tccacaaggc aatgcttacc aaaatacgaa ctcaactgtt gctttcatcg gtactgtcga
     7981 ttggcaaaca ggcaaatttc tagtagagaa ttttcatgaa atcgatggcg gtttagattt
     8041 ttatgcaccc cagacctgtg aaaacgaagc aggccaaaga ataatgattg cttggatgca
     8101 aatgtggcag cgtaaaatac ctacgaatga tctgggccat ggttggtcag gttccatgac
     8161 cttgcctaga gagctgaggg tggctgataa tcaattgttg caacggccag tttcatcaat
     8221 ttatcaagta attgatccgc aggaaaggat tgaatgggcg aagactgaag agaatcgctt
     8281 cttactgaag gacttagtat atgaccagca ctatttacgc ttggaaatca atttaaaaca
     8341 ggcaacgaaa ctagaacttc actatgcgaa gggacccgac catacattac tgcttaacta
     8401 tgatgttgaa cgggagtgct ttactgcttc cagggaacac atgccgtatg atttatcagg
     8461 agctgaaaag gaagtgttga aaaagcgcag tgtgacgatt cctttggaaa ataattgtct
     8521 aaccatcgaa attttccgtg atacttcagc tattgagctt tttctaaatg atcgtctgac
     8581 tatgagtaca actttttatg agacagaaaa aggacaggat tttcttttgc tggcagacag
     8641 tgaagtaacc ttttcattgg aaagcggctt aattaatcta tagaagggag agctcagtga
     8701 tgatttatgg ttcaatcgaa gcaggcggca caaaatttgt gtgtgccatt agcgatgaag
     8761 aaatgacgat caaggaaaga gtgagctttc cgacaacgac acctgaggaa acaatacctt
     8821 tagtcattga cttcttcaaa caataccaag cagatttagc agggattggg attggctcat
     8881 ttgggcctat cgatatccat cgcgattccg ccacttatgg gtacattacc tcgaccccga
     8941 aa
//
LOCUS       DACBZK010000086         8872 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.089, whole genome shotgun sequence.
ACCESSION   DACBZK010000086 DACBZK010000000
VERSION     DACBZK010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.089"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(56..349)
                     /locus_tag="IVD66_002373"
     CDS             complement(56..349)
                     /locus_tag="IVD66_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HAP6146559.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(377..1042)
                     /locus_tag="IVD66_002374"
     CDS             complement(377..1042)
                     /locus_tag="IVD66_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HAP6146560.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1182..1814)
                     /locus_tag="IVD66_002375"
     CDS             complement(1182..1814)
                     /locus_tag="IVD66_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6146561.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1821..2888)
                     /locus_tag="IVD66_002376"
     CDS             complement(1821..2888)
                     /locus_tag="IVD66_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP6146562.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(2885..3616)
                     /locus_tag="IVD66_002377"
     CDS             complement(2885..3616)
                     /locus_tag="IVD66_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HAP6146563.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(3785..4264)
                     /gene="greA"
                     /locus_tag="IVD66_002378"
     CDS             complement(3785..4264)
                     /gene="greA"
                     /locus_tag="IVD66_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HAP6146564.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4400..5575)
                     /gene="mltG"
                     /locus_tag="IVD66_002379"
     CDS             complement(4400..5575)
                     /gene="mltG"
                     /locus_tag="IVD66_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HAP6146565.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            5779..6948
                     /locus_tag="IVD66_002380"
     CDS             5779..6948
                     /locus_tag="IVD66_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAP6146566.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(7215..8837)
                     /locus_tag="IVD66_002381"
     CDS             complement(7215..8837)
                     /locus_tag="IVD66_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146567.1"
                     /translation="MNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAFHINR
                     ALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLYIVTL
                     ITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPLILLG
                     FIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIFLIIK
                     LIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDSELLS
                     FGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLNIIQA
                     PWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNMVKEM
                     NFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPNKDEI
                     TFTLKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTIRYSY
                     TFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT         2818 a         1695 c         1326 g         3033 t
ORIGIN      
        1 atattttcaa aagaaaaaag agaaggtgac aaaaattgtg tcaccctctc tttttttatt
       61 gttttttaaa gtgataggtt ggctcctcca ggttgggatc ataatcaaca agtaaatcat
      121 atcctttaaa gaaccattca tctgcttcct cgataaaaaa aagtgtccca tcaatttcca
      181 ctttctttac aggatgttct ggctgttcaa ctgacattcc aatcgaaaaa ccatcatgaa
      241 cctctgtttt gccgtagact tttccaaaaa aacgtattcc gtaagtttct ggcagatcaa
      301 tttctgagtc aaaccacttt tgtgcttttg gcgttaccgt taatttcatc ccaacaacct
      361 actttctctt ttctttctat tgattcatct tatcgtctag aatatccaca tcgcctgtct
      421 ctccaataac cagtagatta tcattttcac gaacatattc atctgctgca ggagaagcga
      481 taaccgtttg atctactctt cgtatggcga ctactgttaa gtcaaaacgt tgcctgaaat
      541 ttaattcagc taatgttttg ttgaaaaatt taggattgga gactcggatt tctgctaaag
      601 aatatttatc tgacaactct aggtaatcta aaatattctt tgacactaaa ttatgcgcaa
      661 tccttattcc catgtctcgc tcgggatgga cgacgcgatc agctccgatc ttttcaagta
      721 ctctggcatg atactcattt tgggcttttg ctaaaatatt tggtacgccc atttccttta
      781 ccatcagagt aactaagata ctggcttgaa tatcttctcc aatagcgaca attacatgat
      841 cgaaatttct tatgcctaat gatcgaagtg tcatttcatc ctgtgcattt gccacaacag
      901 catgagtggc tatattcata tattcattga cccgatcttc attactatca atagccagta
      961 cttcttgacc agcttcgatc agtgttcggc agatacttcc gccaaatcgt ccaagaccta
     1021 caattgcaaa attttgtttc accgttttcc tcctttagta tcttcttttc tcagtataac
     1081 aaagccttta caaaaacaaa agcaagcatc attattgtaa aaaagccaag aaaaataata
     1141 gttattttct cagcttttga ttatcctctt tatcatcgtt tttatttcac caaaccatgt
     1201 ttgaatgcat agatagcggc ttgtgtacgg tcttccactt ctagcttagc caatatattg
     1261 gaaacatgtg tttttactgt tttcagtgta ataaacaatt cgtccgctat ttcctgatta
     1321 ctttttcctt cagaaatcag cattaaaatt tcattttccc gattcgttag ttcttcatgt
     1381 aatacaggct catttcgccg actcattttt tccatcattt ttgttgtcac ttctggttct
     1441 aatactcgct cgccacgttg cgttgccctt atagcatcag caatttcatg tgcggtagag
     1501 gtcttcaaca aataccctgc tgcacctgct tcaatggcag gataaacttt ttcgtcatca
     1561 ataaaactgg ttacgataat gattttagct tctggccaat cttttaagat tgcttttgtt
     1621 gattcgatac catccatttc ttccatgact aagtccatta aaatgacgtc cggtcgaagt
     1681 gtcatcgcct tctcatagcc ttgtcgtcca ttttcagctt ctccaattac ttcaatgtct
     1741 tcttgaatag ataaataaga agagacgcct aagcgcacca tttcatggtc atctactaat
     1801 aaaactttta tcatccttat ctatgcctcc ttcatcaaag ggaccttgat ttctacactt
     1861 gtaccttgac ctttaaaact aatgattttt actgttccac caataccagc tactcgttct
     1921 ttgatattgt tcaatccata acttcccgtt ttcgtttcat tcatattaaa ccctgttccg
     1981 tcgtcaataa tacgtaacaa aagattattg tctattttgt gcaaatatac ctctaattca
     2041 ttggctttag catgtcttaa tgtatttgat aacaattctt gaacgattcg gaacaagtga
     2101 tcctcaatgg aactagatag ttttacatct tctacatccc atttcagcga aatctggatt
     2161 ttattttgca attccttcaa taactgctcg ataccttgct ttaaactttt ctcttctaaa
     2221 ttgactggac gtagatgaag aagcagcgca cgcatctcag actgggaagc gttgatgatc
     2281 tctgctacca ttttcaactg cttgcgaaac atttctggtg tctcgctttt ttctgcttgc
     2341 tccgtcaatg ccgacatcat catcattgct gcaaacaatt gttgcgaaac tgaatcatgc
     2401 agctcacggg ctaatcgatg tctttctaat tctaaaattt cttctttggt ttgtccatct
     2461 acatattggg gacggctcgt tacaatttgt aattcactag atacttcaat cattttttct
     2521 tttatcttag tgatttcctt atcaatatct ttgatgtata aatcgtccga tgcacttggg
     2581 atcggaagaa gcaacaattt ggattcataa ttgccagaag aaagtgcacg cagcttttct
     2641 tcgattttcc cgtattttgt cttttgaata agtgataata atagaaagac aattaatcct
     2701 acacctaagg aaatggctaa caaatggaag ataagcggaa catataataa acgtgcacgc
     2761 agtaattctc cccaccaatg actttgattg ctggcataaa aataagtgaa aagtgaaaat
     2821 agaataataa ggaaagccgc aatccccgaa taaacagcta gcatcgctct ggatattttt
     2881 cccatcatat tcgtatcacc tcgacatctc caatcaaggt attagtaata atcttcaatc
     2941 tacgagggtt ttcatcataa tcactgctgt agattttgat ttgttcattt ttcaaagaaa
     3001 attgctcttc ttcaaacaag acatttccta ctaatgtcgc atgctctaat cggatggcta
     3061 cgcccaaagg tactaagatc cgtgttctgc ctatcccttt tcttacaatc acaatattat
     3121 catcttttgg caaaagcgta ttgcccaaat ctatgatagt atcaccagaa atgacggcga
     3181 tgttgatatc gtcccattca tagacgtcgt ttccaatacg ttggttaccg aataattgct
     3241 gtcttttccg ctcattatta tgtgttttta attgctctgt ttggatcatc atgatctgtt
     3301 tctttcgcca aaaagcattt ttggttaaat ctatccctga aatctctaca cctttcagac
     3361 caataaataa aacggcaaat acagccatca tccataaagc aggactgttg actaagctaa
     3421 aaaaaatgac caaacttcct aatatcaatt gaaaattttg aaatttagta cgaggatgtt
     3481 tgcgcatagc tagatatata ttgaaaatac cgaatatcac taaaagcaaa agtccagtat
     3541 tgtttacgat ttgccaaaca gcaaataaca gcagtagtgc ttcaactacc acaaaaaaac
     3601 gccaagaact attcatcgct ctttctccct cctgacacat tctcatttca tcatacctat
     3661 ttttttaact gttggctata ggactttaga tgtaagatcg tttgttgaaa tctaaaatac
     3721 acaaagagaa aaagatctag agtgtatcat cagtaagatg aactctctag atctttcagt
     3781 cagactacgc ttgttctact ttgacgattt taactaacat atcgccacct ggagtagcaa
     3841 tagttacttc atcattttta cgtttgccaa tcaatgcttg cgcaatagga gaatcattgg
     3901 aaattttgcc agaaaacgga tctgcttcag cgcttccgac aatcgtgtac tcttcttctt
     3961 ctccatctgg tagttcgatg aatgtaactg ttttaccaat tgatacctca tctgcatcta
     4021 caccgtcgtt atcgatgatt tgagcaaaac gaatcatatt ttcaattgtt gtgattcttc
     4081 cttcaacaaa tgcttgttca tctttcgctg attcatattc agagttttcg gaaagatctc
     4141 cgaaaccgcg ggcaattttg attcgttcaa tgatttctcc gcgtttgact gtttttagtt
     4201 cttctaattc tttttctaat ttttctttac cttctagagt cattggataa actttctcta
     4261 ccatgtgtaa cgtctccttt tttcgataaa ataccgcaaa aggtaatctt ttgaggaata
     4321 tagtccaaaa aagattacca cgcttttctt caaatgtaaa tgtttttcta aaaatgatca
     4381 atgtctagag cctgtttttc taagaattat ttacatattt ttccactaat tccatatgtt
     4441 cttcataagt tttagcgaaa taaacatttc cagtgctcgt atctgctacg aaataataat
     4501 agtcattttc tgctggttct aatactgcct tgattgcctc ttcgcttgga ttgtcaaaag
     4561 gtccaggtcc atagccggta ttggtataca aattatatgg tgaatctaca gctgtatctt
     4621 catacgtcac taattctttg tgttcaccta atgcgtataa aacagagata tctgactgaa
     4681 gtggcatatt tgctttgatt cggttaaaga agacttgtgc aatgttttta cgatcatttt
     4741 cttttacgcc ttctttttca actagagaag ctagagttaa aacttcttgt acagtcaaat
     4801 ttttctgctt gatagctgaa taatagtttt gcatgaccgt attcgtcttg ttcaccattt
     4861 caatcactag atccttaagc gaagtactcg tgtaataatc atatgtggct gggaataagt
     4921 aaccttccaa acggtatttt gtgttctcag ctttagatgc actttccaac agttctggga
     4981 atttttggtg caactcgtta aagaaagtct catcattcac taaatctaaa aattctttct
     5041 tgtctttacc agttaccttc gctacccgtt cagcaatctg atcgatatcg tacccttctg
     5101 gaatggcaat tttcccatct gcaacttttg ttggctcaga agtaccgcct tcttgcaact
     5161 gtttgccaat ctcgtcaaga gtcatattag gcgctaactg ataatagcca gcttgaaagc
     5221 cagttaaatt tttaaatttt gtataataat tgaaaacaat cccgctttta ataatattgt
     5281 ccttctccaa aatctcacca atctgcttgt tagaagagcc actcgggatc tcgacttgga
     5341 ctaattggtc atctgattta tctaaaggct tcaacccgct atctacataa cgatacacgg
     5401 taaatccaag aaatccgcca ataatcaata atgtaagagc aatcactaaa atgatcttcc
     5461 tcacaatctt atcttctttt ttacgcagat ttctccgctt gtcgattata tctgctgtag
     5521 ctgccttact ggcttctttt ttatctttac ttgggtgttg tttgtttcct gacaaaacaa
     5581 ctcctcctta ctatcaagtt cgtaacttta ttcattatac atgatatttg aattggcgtg
     5641 aatgatttta tttaaatatt ctatcaaaaa tgtaagtagt aaatccatta ctataagatt
     5701 aaaataaatg ttatcaagat acaagctatt ttagctttat tctttctgta aaaaagaaag
     5761 gagactaaat aaactattat gaaaaaagga aaacatgcta aaaaaagaaa atattcattt
     5821 ttaatgatcg ttgtcgtgtt gtttagcctt agtgcgttct ctacaggaac tattcttgga
     5881 tggcaatttt acaataatga acactctcag atagttgccc atgctcaatc agctcaaaaa
     5941 aagttgatac tgactaccaa tgaacaacag ctcgttgaaa aaatcgatca actattaaga
     6001 aaaaatgatt atattggctc aatttacgta aagaaaaata atcgcatcat catggaaaaa
     6061 ggctatggct atgcgaataa actcacgcaa caaccaaatg atccttctct ttattatcag
     6121 attggttcgg ttcaaaaagc attgactact cttttgattt taaaacaagt cgagcgtggg
     6181 cacctttctt tagatactaa gctggctcaa ttctatccac aaattgctgg cagccagcaa
     6241 attactatcc gtgacttgct gtatatgcgc tcaggcttgc accgaactgc ttctccaacc
     6301 ataccgatga ctgatgaaga agtcgttcaa tttgcgattc agcacttaaa atttacagat
     6361 tatcagacct ctcattatga ttcattgaac tttaccatat tgactggaat tttgatcaaa
     6421 ttaacaaatc aaccgtatga aaaattattg accgatgata tcatcgaacc tttaggatta
     6481 cagcatacaa aattttatga ccaagtcaaa aattcatcca atcatgcact atcctatcaa
     6541 atgtctaaag aggatgatta ctttaaacca ctgacagaat ctgaaacaga gatccataac
     6601 gaattaggga ctggtaatat cagtatgtcc gtctatgatt taaatacgct gtttacacaa
     6661 gttttatctg gaaaactagt ttccaaagac ttactcttct cattatggcg tgaaaatgcg
     6721 aatggacatc catatagtgg tggggtatat agcggagata attatatcct gtcgcaagga
     6781 aatatcgact cttttgatac atctgctata tttagcaaag attcacagga tgctatcatc
     6841 atggaaagca atataaaagc tgacaaaact atcaaactgc ctactgctga tctaagaaac
     6901 caaatctatg acctgatgga aggaactact aagttggcaa atagctgata tgatgaaaag
     6961 atagcaaata ctacttcttt gaatagcatt tgcttaaaaa aagtactcga ctaaacgtag
     7021 gaaagagtgt gggacaaatc taaaaatcaa tttttgctac agactttaat tccaaataaa
     7081 cagaacagaa agaggtgttc ttctttctgt tctgtccaaa ttattctaag atttctcttt
     7141 accaacatta tttgacaaag ggcctattaa atctaaaata gtatctttag attgctaaaa
     7201 tatgtgctag caaatcattc atggcttgtt cttattttta attttatgca ataaaaaaga
     7261 agaacaatta gcgtgattat agaaataaat aatgagattt tagaaaaaaa tgtgtatgaa
     7321 tacctgattg ttactttatt tattccactt tcacttttta ctgtaacaaa aggacctcct
     7381 tgttttagta ctgtagcatt ttttgaatta acagtaaccg ttaatccttt ataccggaat
     7441 acaggtaaaa ctattgtttt gccttttgaa gatttaagcg taaatgtaat ttcatcttta
     7501 tttggagaaa agctactata aataacttga ccatcttctg taacttgatg gtttttcaaa
     7561 agcaattgat cttttttata gcctataggt acataatcaa aattctcaaa ttcttcaagt
     7621 ttattttcca tttgttcatt agaataagtt ccttgaaaat tcatttcttt caccatgtta
     7681 actactgatg aataatttaa aattgaaata gctaatatta ataatagtat aaaatttctt
     7741 ctccttgtat aagaaaattt ttccaactgt ggagaaataa atagagatac tgaaaaagat
     7801 atgaacaatg ttgaaaatat cataaaacgc caaggagctt gaataatatt taaaggagta
     7861 ttttgtaagg caaaccatgg aaatattttt gtacaaagta gaatagatat tatacccatt
     7921 atataagtga ttttagataa gattcctaat tttttaaagt taaatgttag tataattaaa
     7981 caaataagca aagttaagcc aataccaaat gatagtaatt ctgaatctat acttccaatc
     8041 aaaaactctt tacccagata aattgctctt ttttgtaata tatccacata aggtctattc
     8101 agatcttgat acaatgtctg ctcaatcata ggacctataa acgctagtga aagaagtaaa
     8161 gtaactatag cagcttttat taatttaata attaagaaga tttctatttt ctttttccga
     8221 taaaattgaa taattaaagc aattataatc attaccatag tcatagctac agaaagaaca
     8281 tgagtgtaaa ttaataaagt catgctaatc gccaacataa cccaagattc tttttttgag
     8341 tcgtaaagct ttataaaccc gagtaaaata agaggaagta ttgacattgc gagtaattcc
     8401 cccattgccc ctcgaagaaa tatttctaca ctcctaaaag aagatgttgt atatataata
     8461 gcgaaaaagg agctagtaac atgttttttg gtaatttcat acattacata atgacatata
     8521 aatagagtaa tgagcgtaac aatataaaga aaaaggttat agcctattgc taaattagta
     8581 aacttgatca ataaaaataa aggatataga gttaaccatg ggtaaaaatt atttacttgc
     8641 atgccatatg atctaaacgt ttcaaaatta ataggggagc taaaaataga ttctaaactt
     8701 aacgcacgat taatgtgaaa tgccgtatca taaaagccaa atatttccat gtttttaaat
     8761 gctggaaata aatataataa actaacaaat gcataaacta taaatatttt tacagaaaaa
     8821 atttttttca aattcatata ccacctcatg tttttttata ttacatatag ta
//
LOCUS       DACBZK010000087         8732 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.091, whole genome shotgun sequence.
ACCESSION   DACBZK010000087 DACBZK010000000
VERSION     DACBZK010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.091"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            2..74
                     /locus_tag="IVD66_002382"
     tRNA            2..74
                     /locus_tag="IVD66_002382"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="IVD66_002383"
     tRNA            78..150
                     /locus_tag="IVD66_002383"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="IVD66_002384"
     tRNA            155..225
                     /locus_tag="IVD66_002384"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="IVD66_002385"
     tRNA            238..311
                     /locus_tag="IVD66_002385"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="IVD66_002386"
     tRNA            323..394
                     /locus_tag="IVD66_002386"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     gene            660..1853
                     /locus_tag="IVD66_002387"
     CDS             660..1853
                     /locus_tag="IVD66_002387"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HAP6146568.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="IVD66_002388"
     CDS             1983..3455
                     /locus_tag="IVD66_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6146569.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="IVD66_002389"
     CDS             3538..4326
                     /locus_tag="IVD66_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HAP6146570.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="IVD66_002390"
     CDS             complement(4393..5061)
                     /locus_tag="IVD66_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAP6146571.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..6888
                     /locus_tag="IVD66_002391"
     CDS             5176..6888
                     /locus_tag="IVD66_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6146572.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6891..8663
                     /locus_tag="IVD66_002392"
     CDS             6891..8663
                     /locus_tag="IVD66_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6146573.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         2622 a         1487 c         1945 g         2678 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattttttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtagctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agcacaattg
     6301 atccctcgtc tatttgatcc gacagaaggc aaagttgaag taggtggtgt agatcttcgt
     6361 caagtaaatg aaaagagttt aagacaaacg gtttcctttg ttttgcaaaa agcaatttta
     6421 ttctcaggaa cgattgctca aaacttgcgc caagggaaaa agaatgcaac agaaaaagag
     6481 atggaacatg cttcttctat tgctcaagca aaagaattca tcgaaaagtt atctgatcgt
     6541 tacgaagcac caatagaaga acgtagcagt aacttttctg gtggtcaaaa gcaacgttta
     6601 tccattactc gtggcgttat cggtaatcca aagatcttga tcctagatga cagtacgagt
     6661 gcactggatg ctcgctctga aaagctggtc cgagaagcac tcgatcgaga tttgaaggga
     6721 acaacgacga ttgtcatcgc acaaaaaatt gcttctgttg tcaaagcaga ccgcatctta
     6781 gtattggatg aaggcagatt agtcggcgaa ggaacccatg aggaattggt agctggaaac
     6841 cgtgtctatc aggaaatctt tgaaactcaa aaaggaacgg aggagtaagt atgactgatc
     6901 taataaaagc aagtaaattt ttctatcact atttgaagcg gtacaaactc tcctttttct
     6961 ttatctttat cacagtgatc attgctacct atctacaagt aaaggcacct caatacatcg
     7021 gggaagcttt tcaagaatta gctaattacg taggaggctt gatgcaaggc gtagacgata
     7081 aaagcaaatt tgtttctgta atatggaaac tcttgctgtt ttatgtacta gctagtgcag
     7141 ccaactttat ctatagtatt ttgttcacac aagtagtagg gaagtcaacg aaccgaatgc
     7201 gtatcggtct attcaacaaa ttggaaaaat tgacgatccg tttctttgat tctcatcaag
     7261 acggtgaaat tttaagtcgt tttaccagtg acttagataa tattcaaaat agtttgaacc
     7321 aagctttgct tcaagtcatc acgaatgctg ttttacttgt cgggatcttg atcatgatgt
     7381 tccgccaaaa tgtagagtta gcttgggcta caattgcttc cactccagta gccgttttga
     7441 tagctgtctt gattatccgc aaagcacgga aatatgtgga tcttcagcaa gatgaagtgg
     7501 ggaaactaaa tggttatatg gatgaaaaaa tcagcggaca acgtgtcatc atcacaaatg
     7561 gcttacaaga agaaacgatt gaaggattct tagagcataa tcaaagtgtt cgcgaagcaa
     7621 ccttcaaagg acaagcttat tctggtctac tatttccgat gatgcaagga atgtcactgg
     7681 tcaatacagc gatagttatc tttttcggcg gctggttagc attaaatggt gatttggaac
     7741 gttcggtggc attaggctta gttgtgacat tcgtccagta ttcacaacaa tattaccaac
     7801 cactgatgca gatttcatct ggatacagca tgatccaatt agcgattaca ggggcaagac
     7861 gattgaatga aatatttgat gaaaaagatg aagtcaaacc agaaaacggt aaagcatttg
     7921 atggtgttga aaaaggtctt gcgttgcagc acgtagattt tggttattct ccagaaaaac
     7981 tagtcttgaa agatgtctcg atcaatgtgg acaaaggaga aatggttgct cttgttggtc
     8041 caacaggatc ggggaaaacg acgatcatga atctgctaaa ccgtttttac gatgtcaatg
     8101 atggttcagt agtcatcgat ggaatagata tccgagatta tgatcttgat gcattacgta
     8161 gacatgtagg aatcgttttg caagaatctg tattgttctc cggaacgatc aaagacaata
     8221 tcacattcgg caaaccggac gcttcagatg aagaagtcat caatgcagca aaacaagcga
     8281 atattcatga cttcatcatg acgttagaaa aaggttatga tacagagata tccgaagaaa
     8341 ataacttatt cagtacaggt caaaagcagt tgatcagtat tgctcgaacg atcatcacaa
     8401 atccatcttt attgattttg gatgaagcaa caagtaatgt agacacggta acagaagcaa
     8461 ggatccaaaa agcaatggat gaagcaatca aaggaagaac cagctttgtg attgctcacc
     8521 ggctgaaaac aatcttgaat gcagatagaa tcgttgtctt gcgtgatggg gaagtcattg
     8581 aagaaggcag tcatcatgag ttattagcag aaaatggatt ttatgcggaa ctttatcata
     8641 atcaatttgt atttgaaagt taaattaaaa gaacctcgtt ataacggggt tctttttata
     8701 tattttatgt tgtttgtttt tataaggggc ag
//
LOCUS       DACBZK010000088         8722 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.092, whole genome shotgun sequence.
ACCESSION   DACBZK010000088 DACBZK010000000
VERSION     DACBZK010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8722
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.092"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            7..2199
                     /locus_tag="IVD66_002393"
     CDS             7..2199
                     /locus_tag="IVD66_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HAP6146574.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            2216..2692
                     /gene="ybeY"
                     /locus_tag="IVD66_002394"
     CDS             2216..2692
                     /gene="ybeY"
                     /locus_tag="IVD66_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HAP6146575.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            2670..3071
                     /locus_tag="IVD66_002395"
     CDS             2670..3071
                     /locus_tag="IVD66_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HAP6146576.1"
                     /translation="MPMDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFG
                     ILALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKD
                     MAAGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            3086..3985
                     /locus_tag="IVD66_002396"
     CDS             3086..3985
                     /locus_tag="IVD66_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HAP6146577.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            4128..4940
                     /gene="recO"
                     /locus_tag="IVD66_002397"
     CDS             4128..4940
                     /gene="recO"
                     /locus_tag="IVD66_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HAP6146578.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            5324..6241
                     /gene="glyQ"
                     /locus_tag="IVD66_002398"
     CDS             5324..6241
                     /gene="glyQ"
                     /locus_tag="IVD66_002398"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HAP6146579.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            6243..8318
                     /locus_tag="IVD66_002399"
     CDS             6243..8318
                     /locus_tag="IVD66_002399"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HAP6146580.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKKSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
BASE COUNT         2943 a         1560 c         1853 g         2366 t
ORIGIN      
        1 aagcacatgt tgaataaaac actgcagaaa ctacaagaaa aacttggaaa ggcagcattg
       61 cctttcctgc tgttcttgtt ttttatcatt atctgcggcg ttacatttag tagtgtcaaa
      121 caaaaggcca atgatttcag agaaggccaa gtagcagaag aaagtatccg tgcgaacaaa
      181 acgatcgaga acacggaaga aaccgaacaa aaaagaaaac tggcagcaga agcagtcact
      241 ccagaataca cttaccaaaa agatcttgca gatgaccaga acaatcggat caagcaacta
      301 tttgaattga tcgataaaac gaatgatgcc atcaacaaat cttatgacga aaagattgat
      361 aaggcaaagg aagatgaaaa tatcccaaag cctactacag aagagcggat cgccgcgttg
      421 aagaaaaatt ttgaaaatgt gaatgcagaa aatgttgcgt tttatcaaaa actaccgaac
      481 aatttttatt cgacgatatt tgaaatgact gaaactgaga tccatactgt gagggatgag
      541 agtctgaagc tcattgacga acagatgagc aaacaagttc gtgaaagtga attggaagct
      601 tttaaacaag aagcagaaga gcaaatccaa tatttgaatg tcacaccagc acaacaacaa
      661 atgattcgct acttagtgga tcaaggtatc gtagtgaatg acgtattgaa tgagaaaaag
      721 acagaagaat tgaaacaatc cgcacgagaa gctgtacaac cagtgatgat cttccaagga
      781 gaaatcattg ttcgtgaagg taatcaaatc gatgcttcag ctatgaaaaa attggaatta
      841 ctaggactga ctaatcaaac aacttcgatt tttccgctaa ttgccatggt tttagctgtt
      901 ttgcttcaaa tcggcgtact gatttataat tcacttcaat tccaaaatgc aggagaaaga
      961 acaaaatacg tgcttttcta tgtgacagct atgtcagtca gcatagtgct gatgaaattt
     1021 ttccaattat tccaaacgga acaagctact tatatcccgc tgttttatcc cgctgctttt
     1081 gcaccacttg ttttaagctt tttcttgaac cgaagagcag ggatcatggc tggtattttc
     1141 caagcagtat ctgcactttt cattttttat gattcgattg gcacgaactt tctaacgatt
     1201 atcttgatgt cttatgtttt ctctgggctc atggcaacga ttgtcagacg caaacggatc
     1261 tcagaacaag gattatctgc tgccatgtgg gtcattattt ttcctgtgat gatggatgtc
     1321 attttgatcg tctatcaagg aatgagcttt ggtgatgcaa cgacttggtt aatgcttgtc
     1381 tgcgggttca ctggtgcact cttctcattc ttgctgacga tcggtctaca cccatatatt
     1441 gaattgatgg tcaatgatga cagtgtaatt gtattaaatg aactcagcaa tccaaatcat
     1501 cctttattga aacagttgct ggaagaagcg ccaggtactt atcatcatag tatgatggta
     1561 gctaatctaa gtgctaacgc tgtagcagaa atcggcggac gttctttgct aactcgagta
     1621 gcttgctatt atcatgatat cggcaagatc aaacatgcta gctttttcgt tgagaacttg
     1681 ccttcaggag cggaaaaccc gcacaatttc ttattgccag aagacagtaa acatattatc
     1741 tttggacatg tgacagatgg agccaaaata ttggaagatt ataatatgcc gcaaatggtg
     1801 atcgatattt gcaaacagca tcatggaacc acgctaatgc gttatttcta catcaaagcg
     1861 aaagaacgca atccggaagt aacagaagag caattccgtt atcctggacc aaaaccgcaa
     1921 agtcgtgaag cagggatcgt caatattgct gacagttgtg aggctgcagt acgggcaatg
     1981 gatcatccga cgagcgaaaa aatcgaaagt tttgtccata atcttatcga agagcgtatt
     2041 tccgatggtc aattagacga tagtggactg accttgaaag aaatccgaaa agtggaaaaa
     2101 tcattgatca gcggtttaag tagcaccttc cattctcgga tcaaatatcc taaaatgaaa
     2161 acagaagttg agaagataaa ggaagaacaa gaagaataga aagaagcgat gtataatgga
     2221 tattaccttt atggatgaaa caaaccaagt ctcagaagag aaaatgaaag aaatcgatga
     2281 cttgctgcaa tttgcagcat cttatttaaa gctgccagag gaaacagaaa tgtctgttac
     2341 tttcatggac aatgcggcaa tccaagtaat caatcgtgat taccgtggaa aagatgcacc
     2401 gacagacgtc atcagttttg ctctggaaga agaaggcgaa gacgaaatcc cagtgatttt
     2461 tgaagatgga gagaatccat tgcctcgtgt actaggagac atcatgattt ctattgaacg
     2521 tgctgctgaa caagcagaag cttacggcca ttcatatgat cgggaacttg gctttttagc
     2581 ggtacatgga ttcttgcata tcaacgggta tgaccatatg acaccagaag atgagaaaga
     2641 aatgtttggt ttacagaaag agatcttgga tgcctatgga ctcaaaagat aaaaacgtag
     2701 agaaaaacaa acatttcctg atgtctgtgg aatttgctgt ccaaggagtc aaaaccgttt
     2761 ttgaggaaga acgcaatatg aggaaacatg ttgcgttcgg tatccttgct ttatttatgg
     2821 gcgtgatttt ccagcttgat cggatagagt ggttatggct gcttttagct gtttttctcg
     2881 tttggatagt agagatcatc aatactgttt ttgaaaatgt agtggacatg tttacggatt
     2941 ttcattttca tccgattggg aaaaaaatca aagatatggc agctggagca gttttagtga
     3001 ccgcttgttt tgctgtcatc attgggttga ttttatttgt ccctaaaata tatcatttgt
     3061 tgtttaatta aaaaggagaa cgtatatgcc agaacataaa tcagggtttg tcgcaatcgt
     3121 cggccgcccg aatgtaggaa aatccacatt attgaaccga atcgtgggtc aaaaaattgc
     3181 cattatgagt gacaaggcac agacaactag aaataaaatc caaggagtat atactacacc
     3241 agaagctcag ctgattttta tcgatacacc aggaatccat aaaccaaagc atcgtctagg
     3301 agattttatg gtagaagcag cttacagtgc gttgaaagaa gtggatgcag tcttatttat
     3361 gatcagtgct gatcaaaaac gcggccgggg agacgatttt attattgaac gtctaaaaaa
     3421 cgtgcattct ccagtttatc tgattatcaa taaaatcgat aagatccatc cagacgagtt
     3481 gctgggaatc atcgaagatt attcgacgca gatgcctttt gcacaagtga ttccgatctc
     3541 tgctacagaa ggaaacaatg tcgaacgctt aatggatgta ttagtcagtg aaatgccaga
     3601 gggcccacaa tattttccag atgatcaagt gactgatcat cctgaatact ttatcgtttc
     3661 tgaattgatc cgtgagaaag tcttgttttt aacacgagac gaagtgcctc attctgtcgc
     3721 agtcgttgtt gattcgatga agcgaaacga gaatgataaa atccatatcc aggccacgat
     3781 catcgtcgaa agagatagcc aaaaaggaat cattatcggc aaaggcggaa aaatgctgaa
     3841 gcaagtagga acgaaagcaa gaaaggatat cgaaaatctt ttaggagaca aagtatttct
     3901 agaactttgg gtcaaagtcc aaaaagactg gcgagacaaa aaagtctatc tgcaagactt
     3961 tggctaccga aaagacgaat actgatattc tgaacttctt ataggttaag tatagaaata
     4021 aactggataa aaatccgcac gttgagaaaa acggcggaag atcgaaacat aaataatctg
     4081 gatcggcaga atctgctttt ccagatttat tttttaggag ggagaatatg agccagcttg
     4141 cagaatcgaa aggcttgatt ttatctagcc gtaattacaa agaaaaagat aaattagtca
     4201 aaatctttac ggaatcttct ggcaaaatga tgttttatat caaaggaatc catcggcaaa
     4261 atcagccatt agctccggct ttgctcccct ttaccgaagc agtctatatc ggtaattttc
     4321 gaagtgaagg tttgtcgttt ttaagcagtg tcaaagacgt ccatgcgttt cggaacatcc
     4381 aagaagatat ctttttgagc ggttatggta cctatttgct aaatctagta gatgcagcaa
     4441 tcgaagatca tcaatatgac ccgcatttat tccaatttac gcaacaagct ctgcagcgga
     4501 tggatcaagg agatgatgca gaaatcatca cgaatatctt tgaagttcaa atactgcaac
     4561 gcttcggaat cgcgccaatt tggacgcact gtgtcgtatg cggggaaaca aaaggaaaat
     4621 ttgactattc ttccaaatct ggcggtgtga tatgcgagaa acactggcca atggacgaac
     4681 accgttatca tgcagatcct cgcgctgttt atttcgttcg aatgttttcg gctatttctt
     4741 atgataagat cagtggaatc cacttgaaag aagaaacgaa gcaggcaatc cgtgacctca
     4801 ttgaccagtt gtatgatgaa tatgtcggta ttcatctaaa aagcaaaaag ttcattgatc
     4861 aaatgaagtc ttgggcacac gtattaaaga cgccagagaa aaatatgcct gaaaaagaga
     4921 tacctgaaaa agaagaataa atgaaagata caacaaaaaa atcaaaacta tttgacaaat
     4981 acagggactt ccgtctatta ttaaccgtag attaaataga tcgttcactg agaggatcta
     5041 ttatataaac aagaaaactg caaaatgaat acgtacattg accaagatca gtaaaaaaca
     5101 cgtggtttag cgagttcggg agagtggaag ccggacccaa acgatttttg aagaggcact
     5161 tgcgagtacg ataaatgaag ctgccgaatc tttattcgga agtagggtgg aaccgcgaaa
     5221 ttattcgtcc ctatgtctgt aatcagacat agggactttt tgtcgttttc tttcctgtat
     5281 tcttattgac agcaacgctt aaaaattgaa aggggcaaaa cagatgagta aaaaattgac
     5341 cgtccaagat atgattttaa cattacaaaa attttggtca tcaaacggct gcatgctgat
     5401 gcaagcttat gacacagaaa aaggagcagg tacgatgagc ccatatacat tcttacgggc
     5461 aatcggaccg gaaccatgga atgctgctta tgtagagcca tcccgccgac cagctgacgg
     5521 gcgttatgga gaaaacccaa accgtttgta tcagcatcat caatttcaag tcgtaatgaa
     5581 accttcacct gaaaatatcc aagagcttta tttagaaagc ttgcgtcttt taggaattga
     5641 tccattagaa cacgatattc gttttgttga agacaactgg gagaacccat cgatggggtg
     5701 tgccggtgtg ggttgggaag tatggcttga tgggatggag atcacacaat tcacgtactt
     5761 ccagcaagtc ggaggactac cttgtaaacc agttacttct gagatcactt atggactaga
     5821 acgtcttgct tcatatattc aagaagttga aagtgtctat gatctggaat gggctgatgg
     5881 tgtgaaatat ggcgagatct tcaaacaacc agaatatgaa cattccaaat attcttttga
     5941 agtaagtgac caagacttgc tactaagcaa ctttgaccgt tttgaaaaag aagctaaacg
     6001 ctgtatcgat gaaaatcttg ttcatccagc gtatgattat attttgaaat gcagccatac
     6061 attcaattta ttagatgctc gcggtgcagt atccgtaaca gaacgagcag gttatctttc
     6121 ccgtatccgc aacatggctc gtgctgtagc caaaatcttt gtggcagaac gcgaaaaatt
     6181 aggattccct ttattgaata aaaacacagc aaatccagaa aacatgaagg aggctgaata
     6241 agatggcaaa agacttatta cttgaaatcg ggctggaaga aatgcctgct catgttgtca
     6301 caccaagcat gaaacaatta gaagaaaaaa cagcaaaatt tttagatgaa aaccaattga
     6361 cttatgatac gatcgaaacg ttttctacac cgcgccgctt agcaatcaaa gtaacaaaca
     6421 ttccagaacg tcaagcagac agtgaagaag aagtcaaagg accagccaaa aaaattgctt
     6481 tggacgcaga tggaaactgg acgaaagcag ctgaaggatt tgtccgcgga caaggtctga
     6541 cgacagatgc tatcactttt agagaattaa aaggcgtgga atatgtctat gtaacgaaat
     6601 acactcacgg caaagaagcg aaagaagtat tgacaggttt agcagatgtc attaaaagcc
     6661 tcactttccc agtaacgatg cattgggcag aatacgattt tgaatatatc cgccctattc
     6721 actggatcgt ggcattgtta gatgacgaag taatcccgtt tgagatctta gatgtcaaaa
     6781 caggcagagc ctctcgagga catcgtttct taggcgaaga tgtgacattt gcgcatgcaa
     6841 aagaatatga agaaaaattg aatgaacaat tcgttattgc ttcaccgcaa aaaagacaag
     6901 aaatgatcgt tacacaagca aatgaattag ccgaaaaaaa tcactgggtt attgatctag
     6961 acgaagattt actagaagaa gtcaacaatt tagtcgaata tccaactgtc ttttctggcg
     7021 acttcgaaga aaaatatctt tctgttcctg aagaagtact agtcacttct atgaaagaac
     7081 atcaacgtta tttcgaggta cggaacgatc aaggtatgct gcttcctcat tttatttctg
     7141 ctcgtaatgg tgatcgggta aaattggaaa atgtggttcg aggcaatcaa aaagtattga
     7201 cggctcgttt agaagatgcg gaattctttt ataatgaaga caagaaagct tcaatcgacc
     7261 aatacgttga aaaactaaaa actgttactt tccatgaaaa aatcggtagt atctatgaga
     7321 aaatgcagcg ggtacaagtc attgcccgta tcattggcga acaagtagga ctatctgagg
     7381 aagaattgat ggatctgcaa cgagctgctg aaatctataa atttgatcta gtaaccaaca
     7441 tggtagggga atttcctgaa ctacaaggga tcatgggcga aaaatatgct ctgctgaaag
     7501 gcgagaaacc tgctgtagca acagcgattc gtgagcatta catgcctata tccagtgaag
     7561 gagagctacc tcagtctaca gtaggttctg ttttagcgat tgcagataaa ttagatagca
     7621 ttttttcttt ctttgcagtt gggatgattc caagcgggtc aaacgatcct tatgccttac
     7681 gtcgccaagc atacggtgtc gttcggatca tcgaatcgaa aaaatgggcc tttcctttgt
     7741 ctgttctgca agaaacgatt agtgatgtta tcagtaaaga tacggatcgt ttcggcattg
     7801 gtttatcaga agggcaacaa caggtgatcg actttatcaa aggccgtctg cgccaattat
     7861 tgacaacgaa gaatattcgt catgatgtca tcgaagctgt tttgaatgca gaacaaaaag
     7921 atctgacaaa agtatttgca gcagcacaat tgttcaagca gcatcttgca gatgaagact
     7981 tcaaaccatc gatggaagct ttgacacgtg tcgtgaactt agcgaaaaaa gcggagcttg
     8041 aaaaacaatc agaagtagac cctgaactgt tcgaaaatga agcggagaaa gaactgcaca
     8101 aagcagtaga ggcaatgaaa aaaagctttg ctgaccaaac gatcaacgaa aattatgatc
     8161 agcttgtaag ccttcgccca ctgatcgaaa attattttga tcagacgatg gtcatggcag
     8221 aagaaccagc agtacgtaag aaccgattaa cgcaattaag tcaaattgct gccatggctt
     8281 tgtcgctagc aagtttagat caaatcatca caaaataatt tctaatatgt aaataaacca
     8341 gagaataggc acaaaatagg ctatttctct ggtttatttg ttataaatat aaataactat
     8401 acccgtggtg ctagttaatt ttttcctagg tattatacaa gtaatttgag tcggtcaatt
     8461 tcaactgaat tatctaaact aactgatcta cttttagata attcagttga aatttattgg
     8521 taaactgtcg cttttctttt taaatggcaa aaatttttaa taatatatga caatttagaa
     8581 atcaactata agactgatta attcaaaatg atcttagaat cattgtatga acactaaata
     8641 ctatattgtt ttctattaat cgttatataa acgattatga attcaaagct actttttatg
     8701 acgtcaatca gagagtgtaa aa
//
LOCUS       DACBZK010000089         8694 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.093, whole genome shotgun sequence.
ACCESSION   DACBZK010000089 DACBZK010000000
VERSION     DACBZK010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.093"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(253..1206)
                     /gene="menA"
                     /locus_tag="IVD66_002400"
     CDS             complement(253..1206)
                     /gene="menA"
                     /locus_tag="IVD66_002400"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HAP6146581.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1219..2322)
                     /locus_tag="IVD66_002401"
     CDS             complement(1219..2322)
                     /locus_tag="IVD66_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAP6146582.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(2412..3347)
                     /locus_tag="IVD66_002402"
     CDS             complement(2412..3347)
                     /locus_tag="IVD66_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HAP6146583.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            3649..5583
                     /locus_tag="IVD66_002403"
     CDS             3649..5583
                     /locus_tag="IVD66_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP6146584.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            6040..6456
                     /locus_tag="IVD66_002404"
     CDS             6040..6456
                     /locus_tag="IVD66_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAP6146585.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            6470..7036
                     /locus_tag="IVD66_002405"
     CDS             6470..7036
                     /locus_tag="IVD66_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HAP6146586.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            7059..8045
                     /locus_tag="IVD66_002406"
     CDS             7059..8045
                     /locus_tag="IVD66_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAP6146587.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(8200..>8694)
                     /gene="scm"
                     /locus_tag="IVD66_002407"
     CDS             complement(8200..>8694)
                     /gene="scm"
                     /locus_tag="IVD66_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAP6146588.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSK
                     TSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYK
                     KSKR"
BASE COUNT         2561 a         1679 c         1759 g         2695 t
ORIGIN      
        1 gataaacggt gttcaaaagc cagtttctcg gtattaagcc aaatttatgc aaaaatgtgg
       61 aaagccattt tcacaaaatt tttcttaata ctcgaaacta agcgactttt tcacaacctc
      121 ctgataaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaaccaa acgaaaaata
      181 taaggagcta tttttatttg gctgttctta ttacttgatg cagggcagtt ttttcacaac
      241 ctcttcatgc tgttaaatgg cttgcataat gattgttagt aatagcccca atacataact
      301 ggcattgaat aagaccatat ttttgatgga atagctgaaa ctgataggct ggggtaacgt
      361 ttgcttgaat tgatccaaat gcttcttcac aattggcaag gtcaagaagg tgaccaagat
      421 cggccattca tagataccgc tcaacaaccc cattaaaatc acgaaatagc aagcatacat
      481 caatagctgg aataagactg ttcccgcagg acgtccgata taaaaaacta gtgtatagcg
      541 atgattttca atatcacggt caagatcccg caaattatta gccaacatga tattggcaat
      601 cgtaaacacc aagggtaagg aagctaatac gattgctgct atagcccaaa gatttcctac
      661 caaatcaaat tgtccagatg aaaagttgac tgtcagatca tagacatctg aaccgaatgt
      721 attgacataa acgaccatgg caaaaattcc aaggcccata gtcaccccac tgaaaatttc
      781 ccctaaaggc attcgagata aaggaatcgg tccgaatgta tagaatactc caataaaaca
      841 acagataaat cccatcaaaa gtaaaagcca acccgtattg atcgttagaa taacgccgat
      901 aacaaaaaca aatgcaatca tagctaaaat catgtttcga atcaatacag gagatagatt
      961 tctgcggcca atgacatttt cttcatactt atatacttca gaatgagcct tttcataatc
     1021 catgtaatta ttgatagcgg tagtcgctaa atcaaaaact agcattccaa taaaaaataa
     1081 aaaagtgttt agccaatgta tctcatgaaa aaaagcgata gagaataata cccctaccgc
     1141 aaaaggaaat acactagcca cctttgttcg tatttcaact acttctaaaa agatttttag
     1201 tgtcatggtt cgtactcctt attttagttc agaacggtca cccatcgtgt aatgggagtc
     1261 ctccgataat ttgaaggtgt ctttgattgg atcggtcaca tatactttat cgtcttttgt
     1321 cacgaagatc gcttccgtcc cgttattcaa ttcgctttcg acgtattcca gtcctttttt
     1381 cacacccatt gaaaagactg ctgtagacaa cccgtcacca tcaattgatt tatctgttat
     1441 gatcgtgaca cttgcgatat cattgtcgaa cggataaccc gtttttggat caaacaaatg
     1501 atggtatttt ttgccatcta cttctaaata acgctcgtaa attccagagg taactaatgt
     1561 tttgttccgt tctttaatag aacctaaaac agatccgcga gccatgttcg gatcttggat
     1621 gccgactgtc cagtcttggt tttcgcctct tgggctgtgg cctaagacat agacattacc
     1681 gcccaagtca acgatggcag tggtcactcc ttgttttttc aagactttca ctacttcgtc
     1741 cgtaatgtaa cctttggcga ttgcacctaa atcgatgatc attccttttt cttttagata
     1801 aacagttttt tctttgtcat ttagttcgat cttatgataa tccactaatt tcaatgcctg
     1861 atcgatttct tcttgggaag gttttctggc gtcatcaaaa ccgattcgcc ataattgtgt
     1921 gattgcacca atcgccatat cgaatccgcc ttgagaatct tggctatatt cgtaggcccg
     1981 cttgactaac gtgtagacgt catcagaaac ttttactggt ttgatcccag cttgctcatt
     2041 cacttcatcg atctcagaac ctttttgatt gatcgtgatt ttatcaccaa gttcttttac
     2101 tcgatcgaag gcaggtttca atgctgattc tttgccttca tcatacacac ggatacgaac
     2161 gtaagtccct aacaagaact gttcatcaga atatggatct ttcaatatct tggtagctgc
     2221 tgaactttca gtggttgttt tatttgctga gttgctgcag ccagttagca ccataaaaga
     2281 gatgcccagt gtgattaagg aaaatagtag ttttttccgc atctttttcc tctcttcatt
     2341 ttgaaaggtg agacgactgc ctaatctggc tatcgtccca ccctccaact tttattagta
     2401 tgattatgtg attatttttc tgttacgata ttatctactt cgattgtttg agtgtcgcct
     2461 ttttcagctg cattcactaa ttgttgtgcg tacatgatga atgaatgtga gctgtgtgta
     2521 gcacctgtaa caacttctac attagcaggt gagccatctt cttcgcccat tgctttgacg
     2581 aattcgtcgt tcagagtagg gatgtaagtt tttggttctg taccgctttt tgctttcata
     2641 ttttcattat attctgtatc atcttgtttt gatttaccgt ctttgtcgat ataatcaaag
     2701 tttgattcag ttactttgcc gccagcaact gtcatttcga attgcacacg gtagccgtta
     2761 gagtagttct tttcttcaag cttgtaagtg ccgtctttca aatcagcacc attgtcgatt
     2821 tcgattgtat ctgtgttacc agcttgagca gcttggatca attgttgtgc gtagttttgg
     2881 aagctttcag atgagtgagt agctccagtt acgacttcca caccgcttgc gctttgtgct
     2941 tttaagaatt ggtcattcaa ctcaggaatg tatttttctg ggtttgtgcc agattttgct
     3001 tccatgtttt tgttgtattc tgcatctttt gtttttgatt cgccgttttc attgacgtta
     3061 tcatattttg attcagtgat tttgccgtct tttacaacca tttcaaagac tgcacggtaa
     3121 ccatttgaat aatttttttc ttctaattta tatgtgccgt cttgcaaatc tccgccagct
     3181 acaacttttg cagatgattc tgttgtgctt tttgcagtcg aagattgtgc tgtagatgat
     3241 tcagaagaag agtttgagct tccgttgtca tctgcgccgc aagcgcctaa cactagagct
     3301 gaaaatgcta atacggcaaa tccagttaca aaacgttttt tcttcatttt aataccccac
     3361 cattccattt ctagtccaca atttttcttt gtgattcatt atacattcta atctttttag
     3421 cctataagtc aactattttt gataaataac ccatgtaata tttcaaacgt tttctttcag
     3481 caaatttcgt gaaaaaacgc tttattttaa aatttgaaaa aaatccaaaa ggagttagac
     3541 aaaagaacag aacatctata taatatatgg agattgtgta ataagtatca aactaaaaga
     3601 attatcatat attcattata tagatagtct ataaggagcg gatgatcaat ggcaaagcaa
     3661 aatattgtcg ttgtaggagc aggatatgcc ggtgtttcag ctacaaaata cttggcaaag
     3721 aaactgaaaa aagaagatgt agcaattact ctgatcgatc gtcattcgta ccatactatg
     3781 atgaccgagt tgcatgaagt agctggcgga cgtgtagaac cagaagcaat ccaatacgat
     3841 ctgcagcatt tgtttgctcg tcaaaagaat gtacaacttg tcacagacac tgtaatcggt
     3901 atcgataaag aacgaaaaat cgtcaagacc aaattaggtt cctatccttt tgatcagctg
     3961 atccttggaa tgggcggaga gccgaatgac tttggtacac ctggtgtcaa agcacacgga
     4021 ttcacccttt ggtcatttga agattctgta aggattcggg aacatattga gaagacagta
     4081 gcaaaagctg cattggaacc agatgatgaa ctgcgtaaag ccatgctgac tttcgttgtc
     4141 tgtggttctg gatttaccgg tattgaaatg attggggaac tgatcgactg gaaaaatcgc
     4201 ctagccaaag attataaatt agatccaaac gaaatcacac tgatggtcgt agaggcaatg
     4261 ccgacgatct tgaatatgtt ggatcgaaat gatgctgcaa aagctgaacg ctatttgcgt
     4321 aagcacaacg tggaattatt attgaatgca ccaatcgtag aagtggctgc tgatcatatc
     4381 aaattgaaag acggacgcaa cattccgact cacacactga tttggacagc tggtgtcaaa
     4441 ggaacttctg acgctgctga ctttggatta gaatcagcac gcggacagcg gttgatcgcc
     4501 aatgaatata tgcaggcaaa aggctacgaa gataaaaaca tctatatcat tggtgattta
     4561 gtcttttatg aagaattccc aggaacaccg acaccgcaga tcgttcaagc tgctgaacaa
     4621 acaggacaca cagccgcagc gaatatcgtg gcttcgatca aaggcggaga aaagcataaa
     4681 tttaaaggaa actatcaagg atttatggtt tctattggtg ccaaatgggg ggtagctaac
     4741 ctatttgata agatccattt aagcggattt ttagctatcg taatgaaaca tatcgtgaat
     4801 ttgaaatact tctttgatat tcgttctggt tattatatgt tccaatattt aatgcatgag
     4861 tttttccata tcaaagatga tcgcaacgtg actcgaggac attcttctcg ttacggcaat
     4921 gtcttatgga gtgtgccact tcgtattttc tatggtttag tttggttcgt tgaagcttcc
     4981 aaaaaaatca ttgggaatgg tgaagtgttc aaaccaagta cttggtttgg tgaaggatca
     5041 tggttcactg gaaacagtgt gttcccttgg acatgggaat acaatgtaac agatgttgcc
     5101 agtggtgctt ctgctgctgg tgatgcaacc acagctgcca gcggagcagg ggcaagtgcc
     5161 ggagaagcag cgactcaagc tgcacatttt ggtttgagtt atgcatacgg tgaagaacca
     5221 atggctgtga ttgagaagtc accagactgg ttcacaaaga tcatgcaagt gatcatgcca
     5281 aacaatgatg tagcaatgtt cttccaaaaa ttcatggtat tctttgaaat tgccttggca
     5341 ttagcattga ttgctggatt attcacatgg ctatgcagtg cgacaacgat tgtattggtg
     5401 atcacgttct gcttatcagg catgttttac tgggtaaaca tttggttcat ttttgttgct
     5461 ttcgcattga tgaacggttc cggacgtgcg attgggttgg atcgctgggt aattccatgg
     5521 ctacaacgta cactaggtaa ttggtggtac ggtagaccaa gttcccagta cggcaagaaa
     5581 taaatagata aagaacgtta tttgaatgca agatttcaat agaaaggggc tgagacaaac
     5641 cgtcacagcc tcctttttat gtaaaattaa aggaataaga tgcccgagat aagcctccat
     5701 gagcaagaca caggtgtcac aacctctgtt acaacctctt gttataaacg gtgttccaga
     5761 agtagcttct tcgaaaaata agccgaaatt tcacaaaaac ttgaaaagta attttcgtaa
     5821 attccttctt atttcttgaa gttgcccact tctgtcacaa cctcttgtta taaacggtgt
     5881 tccacctgct gcttctcggt aataagccca aagaattaga aaacatggaa agctgttttc
     5941 tattcttcgt tcttattact caaagcaaga cacaggtgtc acaacctctt gtttttatgc
     6001 taaaattggg tgagttaatc tggaaaaagg agaacaaaaa tgagccttaa agaatttgct
     6061 gaaaaaagtc tgctcaaacc ttgggatgtt tttattattt tgcttttgac tgttctttct
     6121 tttttaccag tcatgatttt tggtcttcag caaaacaccg caacagcaga aaaagaagcg
     6181 gtactgcgtg tggatggcac agaaatcaaa acattccctt tgatggctgg agaagagagc
     6241 aacacatata cttacaaaga tgaacacgga gattataact tgatcgagat agatggcgat
     6301 cgagtacgga taaaagaagc agattgcgat gaccagatct gcgtacgtcg aggctgggca
     6361 acgaaaaatg gcgaaaccat cgtctgtttg ccacataaat tagtgatcga agtccgttca
     6421 acagatggag gtgacgaaga cagtctgatt tattagacct tcacacacca tgagtaaatt
     6481 acaaaaaatg atttatattt cgctacttgt tgcacaagga gtgatcattg gtttattgga
     6541 aaatatgatc ccttatcctt tttcttttgc gcctggtgca aaactaggct tagccaatct
     6601 aatcacgatc gttgccattt ttaccatgaa aaaacaagac agcttcttac tactttggct
     6661 acgactattc ctgactactt tgctaggcgg aacgatttcc acattccttt atagtatgag
     6721 tggtgctttg cttagttatt ttggaatgtt attggtcaag caattaggac caaaacgtgt
     6781 cagtatcatc ggaattagtg cggccggcgg tttcatgcat aatgtcggac agcttttgat
     6841 ggcttctttc attgcacaat catggacagt catgttgtac ttgccagtcc tttcagtttt
     6901 agggatttta tcagggattg caatcgggat cgcagcgaat tatcttttac gacatgtgca
     6961 gacacttcaa cgattccaaa aagattatga gcagggaacc aaacaaaaat ggagcccaat
     7021 gtttaccaaa aaataatcgt cacacaagga gtttttttat gaagctacat ccaatgtggg
     7081 aaaactatcc tgctttaagt aaagaattga cagaaacact aaaacggatg gaagaaactg
     7141 tccgcctgaa aaacaaacct gtcgaacaag ccatcaaaga aacgatccat gccggcggaa
     7201 agctgttgcg tcctgcctat cagctattgt tctcacaatt tggaccagag caagatcgag
     7261 acaaagccat cgctttggca gcttctatcg aaatgctcca tacggccaca ctgatccatg
     7321 atgatatcgt tgatgaagcg gatctgcgac gtggtcagcc taatatccgt agtcagtttg
     7381 gtaatgtcgt ttctgtctat gcaggagact atttatttgt ctgctgtttt aaactattgt
     7441 ctgattactc cacttccttg aaaagtctcc aattgaattc tcgcagtatg gaaaaagtat
     7501 tgaatggcga attagggcag atggatgatc gctataatta tgaactttct gtaaaagaat
     7561 atttggaaaa tatttcaggt aagacagctg aactgttcca attaagttgt tctgttggcg
     7621 cttttgaaag tggaacaagc gagcgcttcg caaaaaaagc aggagatatc ggactttcta
     7681 tcgggatggc ctttcagatt atcgatgata ttttagatta tacaaaagag agccaggaaa
     7741 tcggcaaacc tgtactagaa gacatgcgtc aaggggtcta ttctttaccg ttgatctact
     7801 ctttgcaaaa aaacaaacca aagctactac cttatttaga gaagaaagcg gcaatgacag
     7861 aagaagatgt cgacgccgta cgcaaaatcg ttgaacatac aggaggcgtg gaagaagcta
     7921 ggaagttagc ggcctcttac acagaaaagg ctttgaagga aataaagaaa ttacctgcca
     7981 cctctcttcg aacaaaagag aatctctttt cccttaccca actgattttg gatcgcaaag
     8041 actgaatagg gaaaggttcg atacgtaaat aaatttctca gaaggaaatc tacgtgtttt
     8101 ttgacaaatt gaattgtagt tcttgtattt atgataaaaa gcaaaaataa agagcaacgt
     8161 ccgttagcga cgttgctctt ttttatcttg aatatttttt taccttttcg atttcttata
     8221 actcataaaa gtgattctta aaccgattac aagtaatata acgcctgcga gtgttatcca
     8281 attattcgat tgacttccag ttttaggaag tgctcttttt gatttgtttc cattgtcatt
     8341 gcttgtttta ttagttaagt taaagttcgt cctgttatcc gaacttgttt ttgagaagga
     8401 gacacttgca tgacgtgtat cgcttgtggt agacgacgtg tctgtactat cgcttgaagt
     8461 tgatgaatct gagctatcac ttgtggtaga ggatgtatct gtactgtcac ttgaagctga
     8521 cgtgtccgtg ctatcacttg tggtagaggt agtatctgta ctgtcacttg aagctgacgt
     8581 gtccgtgcta tcacttgttg tggtagatgt atccgtactg tcgcttgaag ctgacgtgtc
     8641 cgtgctatca cttgtggtag aggtagtatc tgtactgtca cttgaagctg atgt
//
LOCUS       DACBZK010000090         8493 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.094, whole genome shotgun sequence.
ACCESSION   DACBZK010000090 DACBZK010000000
VERSION     DACBZK010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.094"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..173)
                     /locus_tag="IVD66_002408"
     CDS             complement(<1..173)
                     /locus_tag="IVD66_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009325336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6146589.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="IVD66_002409"
     CDS             complement(593..1714)
                     /locus_tag="IVD66_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HAP6146590.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /locus_tag="IVD66_002410"
     CDS             2042..3451
                     /locus_tag="IVD66_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HAP6146591.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /locus_tag="IVD66_002411"
     CDS             3448..4176
                     /locus_tag="IVD66_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP6146592.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="IVD66_002412"
     CDS             complement(4304..5215)
                     /locus_tag="IVD66_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP6146593.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="IVD66_002413"
     CDS             complement(5232..6239)
                     /locus_tag="IVD66_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAP6146594.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="IVD66_002414"
     CDS             complement(6236..8365)
                     /locus_tag="IVD66_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP6146595.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..8477)
                     /locus_tag="IVD66_002415"
     CDS             complement(8370..8477)
                     /locus_tag="IVD66_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146596.1"
                     /translation="MQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2599 a         1728 c         1487 g         2679 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg gtt
//
LOCUS       DACBZK010000091         8289 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.095, whole genome shotgun sequence.
ACCESSION   DACBZK010000091 DACBZK010000000
VERSION     DACBZK010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8289
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.095"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(44..1510)
                     /locus_tag="IVD66_002416"
     CDS             complement(44..1510)
                     /locus_tag="IVD66_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HAP6146597.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1897..2493
                     /locus_tag="IVD66_002417"
     CDS             1897..2493
                     /locus_tag="IVD66_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAP6146598.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2551..3033)
                     /locus_tag="IVD66_002418"
     CDS             complement(2551..3033)
                     /locus_tag="IVD66_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146599.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3139..3336)
                     /locus_tag="IVD66_002419"
     CDS             complement(3139..3336)
                     /locus_tag="IVD66_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146600.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3631..4389
                     /locus_tag="IVD66_002420"
     CDS             3631..4389
                     /locus_tag="IVD66_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HAP6146601.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4449..4877
                     /locus_tag="IVD66_002421"
     CDS             4449..4877
                     /locus_tag="IVD66_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146602.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4923..4995
                     /locus_tag="IVD66_002422"
     tRNA            4923..4995
                     /locus_tag="IVD66_002422"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4956..4958,aa:Gln,seq:ctg)
     gene            complement(5145..5516)
                     /locus_tag="IVD66_002423"
     CDS             complement(5145..5516)
                     /locus_tag="IVD66_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP6146603.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5731..5916
                     /locus_tag="IVD66_002424"
     CDS             5731..5916
                     /locus_tag="IVD66_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146604.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(5999..6187)
                     /locus_tag="IVD66_002425"
     CDS             complement(5999..6187)
                     /locus_tag="IVD66_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146605.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6211..6474)
                     /locus_tag="IVD66_002426"
     CDS             complement(6211..6474)
                     /locus_tag="IVD66_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146606.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6632..6889
                     /locus_tag="IVD66_002427"
     CDS             6632..6889
                     /locus_tag="IVD66_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HAP6146607.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6960..7151)
                     /locus_tag="IVD66_002428"
     CDS             complement(6960..7151)
                     /locus_tag="IVD66_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146608.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7292..7612)
                     /locus_tag="IVD66_002429"
     CDS             complement(7292..7612)
                     /locus_tag="IVD66_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146609.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7635..8069)
                     /locus_tag="IVD66_002430"
     CDS             complement(7635..8069)
                     /locus_tag="IVD66_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP6146610.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
BASE COUNT         2627 a         1635 c         1314 g         2713 t
ORIGIN      
        1 ggaactgctg caaataagca attcctgttt ttatgttcat tgattaatga atagagccca
       61 ttagtttttt gattggttct ttcacagtaa atagcaagat accaccgacg attgctactg
      121 caccgataat accgaagtaa gcagattctg ttcccggtgt gtagaagcgt gcaatttgtg
      181 cattgattgc ttgtgaagaa gcatcagcta agaaccaaat agcgattgtt tgtgattcaa
      241 atgctcgtgg tgctaatttt gttgtcacag acaaaccaac tggtgaaaga cacaattcag
      301 caataaccac gatgaagaaa cttcccaaca accacaatgg acttactttt ccacttgtac
      361 cataaagcat acccggcaac atcaatagca agtacgataa tcctgcaaat aaaagtccaa
      421 gagagaattt cactactgta gatggttgac gttcaccaag tttcgtccac atcgttacga
      481 atactggtgt cagaataaag atgaaaattg gattcaatga ttgataccag cttgcttgga
      541 tcgttacacc aaatagcgta gattgtgtac gttcactagc aaataaagct aagatagatg
      601 aaccttgttc ttgtaatgac cagaaaatga ttgctgcaag gaataatggg atataagccc
      661 atactcttgg tttttcttca gcagttacat cttttgaagt cagcattttg ataaagtaat
      721 acaacggtaa gataatcccc aatacactga ttgtattgac aaaaaagtca attgtcagat
      781 gaccagttag ttgtgccccg ccgaatactg cagcgataac aacaagtgcg atgatcaagt
      841 tacggatgaa tcctttacgt tcttcagttg tcaaaggatt cggcggtgtt gtacccactc
      901 cgtctaatgt cttgcgtcct tggatgatgt attgtaataa tccaaagaac atcccaatag
      961 cagctaaaga gaaccctaaa tgatagttat attcttgacc gattgtacca acgattagtg
     1021 gtgctaataa tgcccctaag ttgacaccca tgtaaaaaat cgaaaatcct gcatctcttc
     1081 gcaagtcagt ctttgaataa agatgtccga ccatgccaga aacatttggt ttcaaaaagg
     1141 cggttccgat aataatcaat gccatcgaaa caaacaatgt acttacacca aatggtaaag
     1201 ccaagacgat gtggccaagc ataatgaaaa ctccaccgaa gaatacagtg cgttttgctc
     1261 ctaacactcg gtcagatacc catccgccga cgatactaga catgtagatc aaagatccgt
     1321 agatcgacat gatagctaat gctgttgctc gtggtaatcc aagtcccccg ttggcaactg
     1381 tatcgtacat ataatagata agtaatgcac gcataccgta ataactaaat cgttcccaca
     1441 tctcagtgaa gaacaaagtt gacaatccct tcggctgccc gaagaagccc ttgtcttgct
     1501 gtttttccat aatctatacc ccaattcttt aaattttcag aaaatattat acatctttac
     1561 cgaaaaattt aactaaaaaa cttatttaag aaatataaac taattttcta taaaagcaag
     1621 taatttttaa tggcaatatc ataaaaaaaa gaagatagag atttaataat tatatatcag
     1681 ctgttttttt caaataagca aaaattccta aaacacaaca atgaaagcga taactaagaa
     1741 aatccttaca taacgatttt tcttattaaa attgtttttt gaacttcgct tattttttgt
     1801 gagcatatct gtttacttac tttttgtaag gtgctatact tcatttcgta atcaattaaa
     1861 aaaatgcaaa acgcaaatca aaggagaaat tttattatga caacttttac tgacactttg
     1921 aaaaaccgcc gttcaatcta tcatctagga cgtaatgttt cactttctaa tgaagaatta
     1981 acaactttga tcaaagaagc aattaaagaa agcccaactg ctttcaatgc tcaatcaaca
     2041 cgcgcagtta tccttttcgg agatgcacat gaaaaacttt gggaaatcac tgaagaagca
     2101 cttcgcccat tgactccagc agaagctttc ccaaatacac aaaacaaatt agctggtttc
     2161 aaaaatggtt atggtacagt attattcttc aaagatactg acgtggtaaa aggtctacaa
     2221 gaacaatttg aattatatgc agacaacttc ccagattggt cagaacaatc aaacggaatc
     2281 gcaacagcta atacttgggt agcattagtt gataaaggat tgggcgcaaa cttgcaacat
     2341 tacaacccag ttattgacga agcagttgca aaagaatgga atatcccttc aaactggaaa
     2401 ctacgttcgc aattagtatt cggttcacca gaaacaccgg ctggggaaaa agaatacatg
     2461 aacgatgccg atcgcttccg cgtatttgga taattttatt tgaaataaaa aacagaggtt
     2521 gtgacaaaca tcttgtcgca acctctgttt ttattctgga tcaatcataa tatcaatctc
     2581 tgcctcatcg tttaagcgtt gggacaaaaa tggaactaat tcttctaatg atgcagaaaa
     2641 tttcagcatc ggtcctcgcc atccgtttcg gaaaaaattc atttttacga ttttagaacc
     2701 ttttggctga tataatacaa ttttattgat ctcagaaaaa ggaacacctt ttttgtcaaa
     2761 gctattcaaa acaagtcctt cttctgtgat tcctctactg tccaacaaaa aactaataaa
     2821 aatcattgct gacaagatcc cttttgccaa ttcatctgct gtaggatgac tgatgagtgt
     2881 ataccaaatg actagtgaca ctaagaaggg tatcaccaag tagacccatc gatttcgcac
     2941 agtccgataa ataatttctt ttcgaaccag ccaaagaaat aaaaacatca caacaacgaa
     3001 taaaaacaat agaaccgtaa agaatgttac catgacaact cgcctcgctt tttcttctcc
     3061 agaaaatagg aaaagaatac tgatttacct tctcaaagaa attggacttg cagcacgccg
     3121 cacgtccaat tgttttcttt attcaaatgt atcatatttt gcaacaacca tgcttgcttt
     3181 ttcatctaat aattcttggt cctctgcagc acattgggca actttgacca cggcgcagtt
     3241 tgtcattttt gatacaactt caccaatgac cgtttttgta aaaccaattg gtttgcatgc
     3301 atattgttct cctaaattaa tcatttcttc cgtcatcaaa atcctcctaa actgctggaa
     3361 cttttctcca cattaccact gctatttctt tggagattta actcattgat ttttatttac
     3421 agttaaaaat caaccttaca ggcattatag cgtactgttt tcgttttcac aattaaaaca
     3481 gctgttgtat ttagaagaat ttttttcaaa aaattaaaac atattcctta aaaactaatt
     3541 atttcctaca tattaaaata taatacttcc atttccaata aaaatacatt tataatagga
     3601 aagataaaca gctgaaaagg gagatttcaa atgaagaaaa aaacgttcaa aaaactattg
     3661 tttctagggg gcacagctgc tcttttatta agcggtacaa gttattacct acatatccat
     3721 tctccagaac atacaatgaa cactgcacaa aaaagttcaa cacaaaaaac gaaaaagaca
     3781 aaagagaaag cagaagtttt actagatgtt ccattagaga gccagtttga ttctccttct
     3841 ttagaaaatg gctgtgaagt cacttcgctt tctatgcttt tatcttttta tggttatgaa
     3901 acaactaaaa accagttagc tgagcaattg gattacgtcc ctgttttcaa tgcagatggg
     3961 actcatggcg atcctaatga aggatttgtt ggtgatatca gtggcggaga ctgggctatg
     4021 gtcgtctatg ttcccccagt tgcctccctt gctcagcaaa tcgtccaaac ggattatcac
     4081 acttttccaa aaaccgatgc tcaactcgat gatatcaaaa aagcactatc taaaggaaat
     4141 cctgtctgga cttctgtgac tatcaatttt gaagtcccag atgaaactga ttttatgact
     4201 tggaccacaa ataatggaga agtaagagtc actcctcttg ttcatgcttg tgtagtcact
     4261 ggatatgaca aagaaaatat ttatgtcaac gatccctatg gtgtaaaaaa tcgagcagta
     4321 ccgatcaacg atttttcggc gattttcact gcaatgggtg gacagatgct aactttggag
     4381 aaaagctagt aattcaaaca aaaatccctt atactcaaga taccaaacct ttgaagggag
     4441 cgtagataat ggaaaaattc acacataaaa aaatggatcc aaatgaaatt ccgattattt
     4501 ttgtccgtga ctgcaaggga aatgttcaag gtaaagtctc tattaatgag tggaacgagc
     4561 gtcgcagacc tgctaccctc aatgaactgg aaatcaaatt gtatcgtcaa tctcttgttt
     4621 attacgcaga tcaagagtac gagaaagcca ccgatttatt gaaatttcta attgctcgaa
     4681 cagagtatac tcgctttgaa tatattgaac gtttagcaaa catctatcat attatgaatg
     4741 aacctgtcaa agaatatcag ttattggaca ccgtcttgtc agtagcagaa ctgattgccc
     4801 ttcctgctgg attagaaaag aaactagtac gccgcctttt acgagtaaag caacaactat
     4861 ccgatcaaga aaaataactt gcgttttttt aggaaagtgc tatgattatt ttgttgaata
     4921 aatgggatgt agccaaactg gtaaggcact tgactctgaa tcaagcaatt gtaggttcga
     4981 accctgccat cccaatttga tgtgcttgct gaaaaaatga accccctgta aaagaacaat
     5041 ctttttgcag ggggattatt gtattatttt tactacttgt atttagttta cataattaaa
     5101 ttatgaataa taaaatcggg cgtattctta atacaaaaac tgatttaccc aataattgct
     5161 aatgctttct ccggaacttt ttctctagga acttcctcat acgtttctat gtgtgctcct
     5221 ttattgctaa ttttcaaata atgattttct tttaacacag aaagaccatt aaattcaacc
     5281 gttcgttctt tcccattggc atcagcagct ttctgcacat accttgctgt accatattca
     5341 tttacttcct ctggtttttg tgtctttaca tagacctctc ctttttcaac taatggattt
     5401 agctgatcaa gtataccagg gatttctcca taacttcctt cagtataata tttcagtcca
     5461 aatagcaaaa taccactaat cgccgccagt ccaatcaaat atttaatcac tttcatcttt
     5521 ctacctcctt gttatatatt cagtatatgg gtcagttaaa gaaattccat ccgtcccaag
     5581 ttggagattt ttctcctact ttagaagcga gaatcgagtg tttttttagt aaaaatgatc
     5641 gttatttgat attattgacg tgtggataaa tcagtttttc tcgttttgtc catgtaaaaa
     5701 atcatgttga tagcaaagga tgtgttcaaa atgaatcaag aagaattatt tcaaaaagtc
     5761 aaggaaatga ttaagaacgg caatttcgat ggcgcaaaac gatttatcga agaacataaa
     5821 gaacaattag gaccttataa agagaaagcc caaaatcttt taaaagatgt aaatatcgac
     5881 agtgtcaaaa acaaatttaa aaatctattc aaataagtaa aactttcact tttgtaaaat
     5941 caaaggagga caatgctgct gcatcgtcct cctttggttc ttttctgaat acttcatact
     6001 aaaataaacg tgtcggatcg taatgataag tcacattgcc gttcagtgag gcttttccca
     6061 ccacatattt acgattctcc aacttcagcc acgcttctcg aaaagccatt aattcttctc
     6121 tttttacatc aatcttttcg atttttccat cgatcaaatc ttgaataagt tgttcatatg
     6181 gattcatttt tttcctccat ctgctgtcaa tcaataagtt gtaaaaatag gttcatatgc
     6241 ttttttggta tctagatctt ctctgacttt gactgtcgta taaataattt tttctactgg
     6301 gatactataa taacttcctt caccattatt gaatcggtga acgtctttct ttgctaaaat
     6361 accatttatt ttattcgtca gtacacgttg ttcgacactg ttacttacaa catagtaaat
     6421 cacccgaata ttattgatca aatgcaaatc gatttctaac actacatgat ccatgaaaat
     6481 cccactcctt ctttcacttt gattatagca agtttctcct ctaatttcaa aatcgataca
     6541 gattttaccg gataaatcca caaaactgct tgcgccattt cgcacaaagt gttattttgt
     6601 atcatggact ttatttatcg gaggcaatag tatgatcgcg atcggtcaat ttgtttttta
     6661 tattcctttt tttattatga taagcattct tttctattac ataaaatgga caaaaaagaa
     6721 gttttcagtt ttactggcct ctttacctgc tgtatatttt acttatcaaa ttttttcttt
     6781 taggcattgg gaaacaacgt ctgtattaat aacacacatc atcgaattga cgctttcagt
     6841 aatttttctt attatttgga tctatttttt atataagaat cagaattgaa tccctcgcat
     6901 gtttaaaaag aaaacgatta aagatgcagc aaatttctgc cgatctttaa tcgttttttc
     6961 tattctgtta taccaaaaaa atgtttgaat cggtgaagga tcgttccttg ttttaattct
     7021 ataaattctt gtgcgatcgg gtacttttct tccaaatttt ctttgttctt ttcgatcagg
     7081 cttttcgctt cttcatattt tttatctgca catagtgctt ttacttcctg taatactttt
     7141 cctgcttcca tttgcctcac cctcttgcca ttttattgct ttaagtttta tttaagttat
     7201 acgcattatt ctagtttcat cccaaataac cttttttcat ttttactcct cgaactaatc
     7261 agttttctaa aggctgattg gttcgtcttt tttatttttc ctccatttca ttctgctctt
     7321 ctgttaattt atctaatgct ttgattgatg ctgcggctct tgcataatca tagctgtata
     7381 attccataaa tttatcaggc agaacaaacc acgctggatg ataaccgtta gctgtgacag
     7441 ggaatccttt atcttgttgg ttatctccat cccatctcag agcaacacct ttttttcctt
     7501 tccactttac taaagcgatc gagtatccct tctttgtttg tgtgccgtct tcaataattg
     7561 ctaaaatttc tattttttct tttggcgcac ggacttcttg aggacgaacc attttctatt
     7621 cctcccttat ctcattactt cacgaccaac acactgcaag gggcatgtga tacgacataa
     7681 gaagcggtcg atccaactaa tgcttgttgt atagcacctt ttcctgtcgc tcccataacg
     7741 atcaaatcaa tattttcttg tccagggatg acattggcaa tcaaatttct tggatctcca
     7801 gtttcaacta ttgcgtggat ctcagcaatg ccgtactctt tggcatcatt gatttttttc
     7861 agcatggcta cttctgttct ttgtttttca tctgcataga tttttgaaaa ggcataggca
     7921 ctatgggtca gctcaacttt gttgatgatt gacacgataa ataagtgggc ttcattgtcc
     7981 tttgctaagt caagggcttc agcgaacgct ttgatcgatt gtcttgatcc gtcaactgct
     8041 accatgatgt tctggtatct tttactcatt ggaaccgcct cctttttctt ttattgtaac
     8101 atctcaagca aaaatacaaa aaatatacgc aatatgtaaa taaaatgatg aacaaaagca
     8161 atttctttca agttatttat acatttcttt tctcatcaga acacctgttc taatcccatt
     8221 atttctgcat tatgtgaaat tcctcatcat ttttcacatc gagcgaacat cattctgtta
     8281 caaaaaacg
//
LOCUS       DACBZK010000092         7842 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.096, whole genome shotgun sequence.
ACCESSION   DACBZK010000092 DACBZK010000000
VERSION     DACBZK010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7842
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.096"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            154..633
                     /locus_tag="IVD66_002431"
     CDS             154..633
                     /locus_tag="IVD66_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146611.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            666..2894
                     /locus_tag="IVD66_002432"
     CDS             666..2894
                     /locus_tag="IVD66_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAP6146612.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            3023..4666
                     /locus_tag="IVD66_002433"
     CDS             3023..4666
                     /locus_tag="IVD66_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAP6146613.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(4739..5284)
                     /locus_tag="IVD66_002434"
     CDS             complement(4739..5284)
                     /locus_tag="IVD66_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HAP6146614.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(5307..5792)
                     /locus_tag="IVD66_002435"
     CDS             complement(5307..5792)
                     /locus_tag="IVD66_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP6146615.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(5782..6594)
                     /locus_tag="IVD66_002436"
     CDS             complement(5782..6594)
                     /locus_tag="IVD66_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HAP6146616.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(6733..>7842)
                     /locus_tag="IVD66_002437"
     CDS             complement(6733..>7842)
                     /locus_tag="IVD66_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAP6146617.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT         2657 a         1495 c         1553 g         2137 t
ORIGIN      
        1 aaagaacgag atggtgtttt tatttctatc aatgaagctc tttttctttg caatcctcac
       61 ttcaatcctc tataatgtcg catatagttt agtaaatgag taaactacta atttacttat
      121 ttactaaaaa taaaaggatg aggagttaaa ataatggaaa taccaacaaa tttaaaacat
      181 aaaccagtaa tcgttgtaga agactatgat aaagttgatg gaagaaatgc attaaatacg
      241 gatgcaaaag ggctttcact gggccttgct cagtggaatg atcgtggaaa agtcgatatc
      301 tcaggcaagg tatggcgaca tactggagaa aaatggtcac gacagtcgga agaattacca
      361 atcacacgta ttttagattt agcgatctta gctgcacaag gaagtttata cttccaagat
      421 gcttatcgtt atgaaaaatt ttatgatcca gaaaatccag tcgtagacat cattggatta
      481 caagggaacc gaatgacggt agaagtagat accaaaaatc caaagatcga tgaagacatc
      541 attttgtatt acgatacact acaaaaagac ggagaactga ttggggaacg attccgtatt
      601 ttaaaacgtc ttttagatga gctaggatat taatagacag agatgatcaa aaggggaaga
      661 gaagcatgga gaatttctca ctaacagaaa accgaacctt ttcacggcta gaaaagcaaa
      721 tgatctggaa gaaaccgaaa agccatcgga caagtgcaga agaatggcgg atcgcctccg
      781 aaatcaaagg gaattggcaa gatcctgaaa tgaaaatcag taacgtactt ttggaaggag
      841 atgccgggtc ggggaagaca caattagcca aagcactatc tgctgatctg caacttccct
      901 atacaaaagt gacctgtttt gcagatatgg acaaatcaga tgttttcgga gccttattac
      961 ctgtagtaga ttctaataag gaacaagacc aagaattact agaagctatt taccaaacag
     1021 atacacttga agctgtactg acactgatcc agaaccatta cggcattgat cctttttctg
     1081 ctaaagaaaa attagcagag ctagttcaaa ggatcgaagc tgattatcca gatgcaatcc
     1141 attacagcta ttacccttct gaaatcgttc gagcgattga aaaaggatat ttattagaga
     1201 ttcaagagcc gactgtcatc cgagatgcct ctgttcttgt ggcacttaac tcagcgctcg
     1261 aaccaaatgg gatgttgaat ttaccgacag gaatcattcg tcgccatcca gattgcgtca
     1321 ttgtgatcac tacaaatcga aattaccaag gaaatcgccc attaaatgaa tctttaagag
     1381 atcggatgca acatgcggaa aaaatggatc ttcctgcctt agaagtcatg gcagaacgtg
     1441 cgatggcgaa aactatgatc caaaaacaag aacttctctt aaagatggca gagattatcc
     1501 gtttgttgga tgaaactgca aaagctaacg ccatcaaagg tgtagcagga atgcgttctt
     1561 atttttattg ggcaaatacc tataagcaag gacaagattt actccagtcg atttatccaa
     1621 aagttttgta taaattatcc actgattcag atgaattggc aattcttgaa caagctttgt
     1681 ctgacagtgg attgctactg gaacttcagg acatattgag aaaagaaaaa tggggtcatc
     1741 ctcaatctga gcatacaaaa ggaagaacca ttagcgccga agaagcaaat gaacgaaaca
     1801 tcactgaaaa tgctgaagaa attctgcgct tagatgaaaa gaaatcgttg tctgctgaag
     1861 aaccaaatga gggagaagag aaacaagaag aaacaataga aaaaaacgag attcctcctc
     1921 aaatgcaaaa agaacgcagt agcgatatcg aaggaaaaaa tcaaaaagaa caacaaacag
     1981 gagatgattc tcaagaaatg tctgcttctg acatggaagc acatgataag gaaatcaaga
     2041 agcaactgaa taaagaagcg cgacaaatca tgaaggaaac gattcatgaa aaagaaggtc
     2101 tcatcgttca ccgaccagct ttccaaggaa aaacgccgga agcacgtgag ctacacatgc
     2161 aagtaatgcc aatagtagaa tcacttagcc ggcaaatttt agagttactg gataatgaac
     2221 aaacagagac gtaccaaaaa ggaaaatacg aaggtcagcg gttcaatgca agcaaagtag
     2281 catatggtga tttgagaaat tttgacaaaa agaacccgcc acatgagcaa ccttctttag
     2341 cggtagctgt acggatcgat gaatctgggt caatgatacg ggatgatcgg atcgaagcgg
     2401 caaaaaaagc agcgattgcc attgccgaat tttctaagaa agtcgatatc ccattgttga
     2461 tttacggaga tacagcagac cgttcgtcaa gagaaaagac ttctttgttt tcttataaag
     2521 aatttgaaga cggatttcaa tggttaaatg aaaaattagt cactatgaaa ccaaggcaaa
     2581 acaatcgtga tggtgctgca cttcgtttag cagcagaaaa attaaacaga caatccgcaa
     2641 caaccaaact gttgcttaat attagtgacg gtcagccaaa agcgttgccg gattatacag
     2701 gcaaaaaagc aaaagaagat atccagtctg ttttgaaaga atatgaacgt caaggaatcc
     2761 tatttgtctc cgcagctatt ggccaagaca aagaagaaat caagtcgatc tacggtgaaa
     2821 gtcgttttgt agatattact gacttgaatg aatttcccaa gcaaatgatt caactgattg
     2881 cccgctatct atgataaaat aaagctcaac gaacgcactt agcagattcg ttgagctttt
     2941 cgtttctagt taccggtaac aaggatactt ctaaaataga atcggttata atcaagaggg
     3001 accgttaaag gagtgaaacg atatgataca agaacaaaaa tggtggaaag aagcagtagg
     3061 ctatcaaatc tatcctgcta gtttcaaaga tagcaatggc gatggtcaag gagacatcaa
     3121 tgggatccgt gaaaaactta attatttgaa agatcttggt atcggcttta tctggatcaa
     3181 tccgatctat caatctccat ttgtcgataa tggttatgac gtaagtgact atcaagatat
     3241 agaagagaga ttcggaacga tggaagattt tgatttattg ctaaaagaag cacatgaatt
     3301 agggatcaaa gtgattatgg atcttgtcat caaccatagt tcggatcagc atcaatggtt
     3361 tgaagaatcg aaaaaatcta aagaaagccc gtatcgcgat tattacattt gggtcgacgg
     3421 ggtagatggc aaagaaccga ataattggac atcgattttc ggcggttctg cttgggagta
     3481 ttctcatgaa actggacagt attatctgca tgtttttgca aaagaacaac cagacttaaa
     3541 ttgggaaagc gagaaattga aagaagaact attcaatatg atccgatggt ggttggataa
     3601 agggatagat ggatttcgtt tagatgcgat ttctcatgta aaaaaagatg aatattcagt
     3661 aaaagccaca gagaaccctt tctcaccctt tcaaaatgtc tcaggaatcg aagaacattt
     3721 gaccgatttg aaacatgttt ttgaagagta cgatatcatg actgtcggag aagcaagtgg
     3781 tgtcactgca gaagaaggac cacaatgggt agggaaagac ggttatttcg atatgatatt
     3841 cgaatttgat catatccata tctggcagca agaaaaagaa gggcaattag atgtccttaa
     3901 attgaaactt gcattaagcg cttggcaaac ttcattggat ggtatcggat ggaacgcttt
     3961 atatatggaa aaccatgatg ttcctcgtgc cgtttcagtg tttggagata ctcgtcccga
     4021 tttttgggct atgtctgcaa aagcaatcgc tatgatgtat ttctttttgc aaggtacgcc
     4081 atttatttat caaggacagg aaatcggaat gacgaatatg ccctttgaat cgatcgatca
     4141 agttgatgca gtagattcga aaagacttta taaaaggctg cttgcggaag gtaagacaag
     4201 agaagaagca ttggatatca ttcgtgaaac aacgagagac aacagcagga cacccatgca
     4261 atggacttcg gaacaatatg ctggtttttc tacacatgaa ccttggctga tcactaatcc
     4321 aaataccaaa acgatcaatg tagaacaaca agaatatgaa ccagagtcgg tcctgcaatt
     4381 ctataagaac atgatccgca ttagacaaac caataaaggt ctgatatacg gttcttataa
     4441 agaatatctt catgaacatc cacaacttta tgtctatgaa agatatttag aagatgaaca
     4501 atatcttatt atggtaaact taacagaatc acttgctgac tatgaacttc caaaagaagc
     4561 agatcagtcc tggacattac tcttgtcaaa ttcctctagc ggagaatttg aagctaaagg
     4621 catactagca ccttatgaag ctcggttata taaaacaaac aagtaaaact tcctcgttaa
     4681 agttcattag ttggactttg cgaggaagtt tttcagattg ctctgtcaat tactcatttc
     4741 aataattcgc tctaggacca ccgatatatt taggacgaga gcgaagggct gtcacgtgag
     4801 cttgtccaag ggttttcaaa cgaggtctga caggtacttg gacatgtttg atatgcatac
     4861 cgattgatgt gtcaccgata tcgataccgg cttgtccaac tacgtgttcc acttcgacag
     4921 gatcattgaa ctggtcaaaa gcagcaacag aacaagcacc tccagcatgt agtgcaggaa
     4981 caacagagac aatttcgaaa ttttttgctt ctgccactgt tcgttctact actaatgctc
     5041 ggttcaaatg ttcacaacct tggacagcta gcgcaatttc tttaggatcc aacaactctt
     5101 ttaacgtacg gatgatccat tgaccaactt ccgcactgga attttttcca atatgtcctc
     5161 caacgacttc gcttgtgctg catcctaaaa caaaaagatc accttttttc aagtgtgcct
     5221 cagccaatat gtcattaact atttcagtca attggtcttt taattctttt tctgacaact
     5281 tcattttcta aaaccttctt tttcaattaa tattgcttcc gtgcttgaat acgttgaaga
     5341 cttgcagtta taggaaaggc aagtcccatt ccaatcagat tttggaagat gtttcctggt
     5401 atagaagcca ctccagccgg ccaatcatat aaaatccaac cggcgatacc atagccgatg
     5461 atcataacta agcttcctaa taaaagccct aatccccaca tacgagtaga agatttgctg
     5521 aaagaaccag caacatatcc ttgtaacccg tggatcacta atgaaaaaac tgcccactgc
     5581 ggatatcctg aaatcaaatc gatcaataga ccactggaag caccaacaac taatccaccc
     5641 gttggaccat aaagaaaagc agcggtatag atcccggcct cgcataatgt cacaaatcca
     5701 ttcgtagccg gtacagggat caaaattgtt aatgaaaggg caactgtcaa cgcaatcagc
     5761 atagcataga tcgttaattg cttagttttc atttctcatt cctccttttt gaataccgcc
     5821 agaccagaca cttccggtat gatcgttcat cagcacgcca ttagaaatac aatgggcaac
     5881 aaatttttta ctttctgcta ctgctttggt aaaatctgcc cctaacacaa gattcgctgt
     5941 tattgcagaa gaaaaggcac aaccggcccc gtttactgtt gtagtgtcga tttttttatg
     6001 agaaaatacc tcataatgat caattgaata gagaagatcc acagcttcat ctccagccat
     6061 ccttgtgccg cctttgatca caatgttttt tgttcctgaa gcagtgagtt ctttagcgag
     6121 atggatcatt tctgttaacg aagagggaag agcttgacca gaaagtaaag cagcttctgc
     6181 caaattaggc gtaatcatcg taacaagtgg aaaaagttct tcgatgagct gcgaaatata
     6241 caattgattg atcacagctt cagtttcttt gaatgccaaa acagggtcta aaatgattgg
     6301 gatattttgt tttgttttta tgaagtctcg aacaaccatg attgcttcac ttgaattcaa
     6361 taacccaatt ttgataccat ctaatgaagt cattttatca atcgaaacta actgtcgttt
     6421 aagcaattcc aaagatatag attccagcat aaatcgctca ttaatatcta gtgcccctat
     6481 agaagtcaag gcgcttagtc cgaatagacc aaaattctca aaagttttta aatctgtttg
     6541 gattcctcca ccagcaaatg gatcagaacc gccaattgtc aagattcttt tcataacatt
     6601 ttcctccatg aataagagta taacgaaatt ttcaaaaaag aaaaacagcc aattggcata
     6661 tttttatctc atccaattta aaaaaacaaa aagaaaagaa agaccaaaat ggatctttct
     6721 ttccttaaat agttaggact tttgtgattt taattctttc tcgatttgaa gccgttgcac
     6781 tttcattgta gctgttcgcg ggattgcatc aaaatcacgg atgataggga cgttcaagcg
     6841 aggaagttca tggacttgct cccaccatcg attccaatcc atttctttat caggagctaa
     6901 agcaataatc ggttgtggag aatgattttt atcccttaca atcactactt ctgccaaaaa
     6961 atctaacgaa tctaataaaa agtcttcaat agctaatgta ctattgatcg tttcgatcaa
     7021 atccacttgc cgatctttca aaaataggtg gccatgctta tccataaaac cgtaatctcc
     7081 gctatcccac caatcgccat aaacattttc ctggaaccgt gcatcttcct tgtaataagt
     7141 caaagcccgt cctttagaca gtaattgtat atgaccatct gtgttttcag gtaggacatt
     7201 cccaactgaa tctgtaatcc gagcgcttgt catgtcttcc agtccaacgc ccatatctct
     7261 tgcatcactt gttttcaaac tctctagtgt atgagcctta agaatcattg gtccgcattc
     7321 actttggcca tatacttgaa gaaataccgc atcctgtgcc atcgacgttc gcaaaaatgt
     7381 cttcattgtc tggttgttta tagcatcaaa agtggagtga tagtatcgga tacccgaaaa
     7441 agcttctgga tgctccttag cagtaaaacg ccactgaaca aagttattcg gatgggtctc
     7501 tagtgcaatt ggccggtgag cttccaacat atgaacaact tttgaacttt gtgcgtttgc
     7561 taaaggcatc ataggaaatc ccatggacat caaagaagag ataccaatat tgaatctgga
     7621 atgcactgga gagatgtgaa aagcgattaa tttcttttcc gaaatttttg tgaaaactgt
     7681 tttttgccat ttcgtccgcc atcccataga atgagcagaa tgacaaataa gtttagggat
     7741 accagttgta ccagaagtat gggtcatata agaaatttca tttttgtcta aaaatgattg
     7801 agaaacagac aaagcaggtt gttccattaa ataaagaata gg
//
LOCUS       DACBZK010000093         7761 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.097, whole genome shotgun sequence.
ACCESSION   DACBZK010000093 DACBZK010000000
VERSION     DACBZK010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7761
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.097"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(552..1898)
                     /gene="gor"
                     /locus_tag="IVD66_002438"
     CDS             complement(552..1898)
                     /gene="gor"
                     /locus_tag="IVD66_002438"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HAP6146618.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(2032..3273)
                     /locus_tag="IVD66_002439"
     CDS             complement(2032..3273)
                     /locus_tag="IVD66_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAP6146619.1"
                     /translation="MTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAYGLRS
                     RAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISAVIVS
                     DPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVAEIRK
                     NTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFGQERN
                     SLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNVYKAA
                     VDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVYKFVG
                     EVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRAPNPM
                     MILTMPVAQPVKPGDMIRKRK"
     gene            complement(3291..4214)
                     /locus_tag="IVD66_002440"
     CDS             complement(3291..4214)
                     /locus_tag="IVD66_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAP6146620.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(4435..6927)
                     /locus_tag="IVD66_002441"
     CDS             complement(4435..6927)
                     /locus_tag="IVD66_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAP6146621.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(6934..7401)
                     /locus_tag="IVD66_002442"
     CDS             complement(6934..7401)
                     /locus_tag="IVD66_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HAP6146622.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(7538..7611)
                     /locus_tag="IVD66_002443"
     tRNA            complement(7538..7611)
                     /locus_tag="IVD66_002443"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7575..7577),aa:Arg,seq:acg)
     gene            complement(7669..7742)
                     /locus_tag="IVD66_002444"
     tRNA            complement(7669..7742)
                     /locus_tag="IVD66_002444"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7706..7708),aa:Pro,seq:tgg)
BASE COUNT         2162 a         1691 c         1247 g         2661 t
ORIGIN      
        1 aaatcagtgt tttgtcctga gtattagaga aacaaatgga aaaatagttc ctcatatttt
       61 gccgtttttt gagctaatac cgaaggacag ctgattgaac actatttgtt cggaaaaagt
      121 gactaactat gacacaattt ttttcacagt cccttttttc acttgatttg attcgtacca
      181 gcgaacttga cgagaacttt cttggtttgg taactatatg gtattctttt aacatcctcg
      241 tttgcttctt ctaatttatt tatacaaagt cacacttttt taaacatctg ttcttcgata
      301 catttctatt tcttttaaac atcgatacca atattttgaa cttaagagtg cataccaaat
      361 ggattcattt actcttcgtc agttacgaag ataatcaaaa tctccaactt ccctacttat
      421 ttcgttttga gaattatcga agcaatctta cataaataac taaaaaacaa aaaaccagaa
      481 aatcagtata ctgattttct ggttttacat ggtttgttca ataaaaagct gttggaactg
      541 ttaatattaa attatcgcat cgttacgaat tcttccgctc ctgttggatg gatggctact
      601 gtattgtcaa agtcttcttt agttgcaccc atcttgatag ccacggcaaa accttgcagc
      661 atctcatcga caccaacacc aatagcatgt aagccgacga ttctttcttc ttttccgaca
      721 cagatcaatt tcatttcgca tttttggcga taatcattta atgcaaagta cattggggta
      781 aagcgtgaac gataaacttt caattcattt tcgccatatt tttccaatgc ttcttcttct
      841 gtcaaaccaa ttgttgcaat tggtggatgc gtaaagacga ctgtcggaac aagtttatag
      901 tcaagataag aatctttctt tccattaaat aaacgttctg ataaacgtct accagctgcg
      961 attgcaacag gagtcagatc taatttaccg atcacatcac caacagcaaa aatatgttca
     1021 tccgttgtat tttggtattt atctactttg ataaaccctt ttttgtccaa ttccacattt
     1081 gtattttcca gacctaattt ttcggtattc ggtacacgtc caccggcaaa aagtacacaa
     1141 tcaccagtta aggtttcacc attttcaaat agcaccgtat attcgtcatt gtttttagta
     1201 atttctttag caatatgatg tgcgtaagtt tttattccag cttcttggta catttggatc
     1261 aaattgtccg aaagcatttt atcaaacgtt ctaagtggtc gttcttttcg atatgcccac
     1321 atgacttcac tacctaaacc acgaaataca cctgaaagtt cagccgcaat gtatccagca
     1381 cctaaaacga ttgctctctt aggtaactct gttaattcaa aaaatccatt tgaatcaatt
     1441 gcgtattctc caccaggaat ggtcatttta cttgcacggc ctccagtagc gatcaagatt
     1501 ttaggagcac gataggtttc accgtttact tcgatcgttt gactatcgat aaaagtagcg
     1561 taacctttta tagcctcgac atgattgcta tctaatcctc tttgataagc accgtgtaga
     1621 aaatcaatat atttttctcg tctttctact agaccggcga aatcaacatt ttttaaatct
     1681 gcttggatac cgtaacttga ggcatctcgt tcaattgttt ccaaaatcgt acttgcttgc
     1741 cacataactt ttttaggtac acaaccgacg ttgacacatg ttccgcccaa ttcattcgct
     1801 tcaatcagca aaacttttgc gccatgcatc cctgctctgt ttgctgaagc aataccgcca
     1861 gagccgccac caattacgat gtaatcatat atttgcattt tgttcctcct tattgaagag
     1921 atcaatcaaa acctttattt aacgatcctt tttctacaga aaacaagtgt aacacttttc
     1981 ttgaattttg tatgcgaaga tgcttaaaac agggatatat cagctttttc cttatttacg
     2041 ttttcggatc atatctccag gtttcaccgg ctgtgcgact ggcatagtta aaatcatcat
     2101 tggatttggt gctcggtcaa tggattcgcc ttcttcatta tgcataactt caacggtttg
     2161 actgaaatga ctgaatcctg gaccataaaa ttcgatttca tctcctacag aaaacaagtt
     2221 tctctgacgt atcgtagcaa tctgtgttgc ctcatcataa gataatactt caccgacaaa
     2281 tttatatact gggattttac gacgttcacc gaataattgt tcgttttcag ttggtgtatt
     2341 gtagtaaaaa cctgtagcta attctcgttg tgctactttc cataactcgt cgatccattc
     2401 ttgcttgcag acatagtttt caggatcttc catataactg tctacagccg ctttatagac
     2461 atttgacacc gtagatacat aatggatcga tttcattctt ccttcgatct tgaagctgtc
     2521 tacgccgttt tcaatcaatt ctggaatatg ttcgatcatt gacatatcca ctgcactcat
     2581 cgagaattct tcttccactt cgcctgtatc agttaaactg tttcgttctt gaccaaaagg
     2641 catatcgaac aatccatact tccagcgaca agattgagaa catccgccac ggtttgcatc
     2701 ccgcatcgac atatggttgg acaatgtgca tcgaccagaa taagagatac acatggcacc
     2761 atggataaat gcttcgattt cggtatccgt atttttacga atctctgcca cttcctccat
     2821 tgaaacttca cgagctaaaa cgacacgttc caacccttct tctttccaga attccaatgt
     2881 ctcaaaatta gttgctgaag cttgagtgga taaatggatc ggcagacctg gggcttctgt
     2941 cgcacaaatt tcgatcaaag ctggatcaga aacaatcact gcagaaatac cgacatcacg
     3001 caaactgcgg aaaaattccc ctgctccatc ttcatttcct tcatgggtga ccatattagc
     3061 agcaacgtat accttcgcat catgttcttt tgcaaaagca actccttcag ccatttcttc
     3121 ataagtaaaa ttacctgcac ggcttcttaa accatatgca ttcccgccaa tatatactgc
     3181 atctgctcca taatggatcg cggtttttaa cttttccagt gttcctgctg gcgctaggat
     3241 ttctggtcgt ttcaattttc tttttactgt catttctttc atcatactcc ttatttgata
     3301 gcagaaggat caatataaaa gaatcctgta tctaattcac ggttttcagg atgcaattta
     3361 ctgatttcgc tagtcatttt ttccgctttt tcttgatccc agctaccttc taaaatttgt
     3421 ttttttgctt cggcgaatag tcgagtgatg tttacgaatt tttcgcctgg agtaaataat
     3481 ccgtccaatt tccatgtaca gtaatgatgc tgataaagtt cattcaattc attcgagaga
     3541 ttcagatcat tgctggcaaa aatatgtgtg ccatgactat cttcataaat agaataatgt
     3601 gtctcttctt ttttaggttc cgagataaaa agacctcttt cacgatcttt ttgttcgtct
     3661 tgtttcgtat agttatagta attctgtagc agtggacgtt tggattgatg gatgcatgta
     3721 gcaccataca caagggtttc tacaggaata tcgagttttt cttccatcgc cttcatctct
     3781 tcaaaaggaa cttcacgagc aagtactgct ccaactgcgc cttttttcgc ccagaaattg
     3841 atttgacgtg cgctcgttac taatgtttca gcatcataaa tatacggtat acgcaattca
     3901 ggattttttt tcatcgtata aataatacct gtatcaccaa ctgtgatcac atctacgttt
     3961 atttctttta aaaaagccaa atattcaggt acatttttca ttttttcagg atgaatgatc
     4021 ccatttacag caatattcgc ttttttacca tacttgtgtg ctaattctac caattgtcgc
     4081 tgttcttctc gtgtaaatga agcaggcaga cgcaatccaa attgctcttc accgaaatat
     4141 agtgtatctg cacctgcagc aagcaactgt tctgcttgtt caatagtttc tactgtggtt
     4201 atgagttcga tcataatttt ctcctcctac aacttcataa tagtagcata gctctaaaaa
     4261 ctttccaata cttcttctat ttaaagtcgg atttttgaaa attatttcac aaaaaatcaa
     4321 aataaagttc gatatattct gtccaaatat aaaaagagat tgtgacaaaa atcttgtcac
     4381 aacctcttaa tcaagtctta ctattataaa aattcagcta cacaggccaa gtaactatag
     4441 ggaacctact gtttcctttt taggtccgcg aacattcaat gtgatcttac cttttgaagc
     4501 acctactgtt acgtggtcac ctaaacgaat ttctccgcca agcaaagcct cgctcaatcg
     4561 atcttcaatt tctttttgaa gtgcgcgacg gattggacgt gcaccatatt caggatcaaa
     4621 tccagctttc ccgatcacat cgattgcaga tggtgtgatt ttcacttgaa tatcttgttc
     4681 tttcaatcgt ttgataatcg ctttgctcat gatttggacg attgtatgga tttcatcttt
     4741 actcaatgaa tggaagacga cagtctcatc gattcgattc aagaattcag gtcggaaagc
     4801 tttctttaac tcttctaaga tacgtttttg catggctttg tgatctttag taacatcttg
     4861 gacattgaat ccgacatttt tttcttctcg aatttgtgtc gctccgatat ttgaagtcat
     4921 aatcatgatt gtatttctaa agtccacttt tctaccttta gaatctgtta aatgaccatc
     4981 atccaatact tgcagaagta aattgaaaac gtctggatgt gctttctcca cttcatctaa
     5041 gagaatcact gaatatggtt tttgacgaat tttttctgtc aactgtccac cttcatcata
     5101 ccctacgtat cctggaggag acccgattaa tcggcttgta ctgtattttt ccataaattc
     5161 tgacatatca acacggatca gggcatcttc acttccaaac atgacttctg aaagtgcttt
     5221 ggccaattct gtttttccga caccagttgg tccaaggaac atgaatgaac caattggacg
     5281 atcaggatct ttcaatccgc ttcgtgcacg gcggatcgca cgtgaaactg ctttgacagc
     5341 ctcatcttga ccaacgacac gttcatgcag aagtccttcc agttctaaca agcgttcgct
     5401 ttcttttttc tccaactgct gtagagggac accagtccac tccgatacaa ctgtagcaac
     5461 atcttcttct gttacacgat cagaataacc ttgctcctgt tttgcttcaa ttgcagaaac
     5521 tttttgcagc tttttacgta gtgctttttc ttgtctgcgt aattgagcag cattttcaaa
     5581 gtcttgtttt tggatcgctg cttccttttc ttgtactagt tcatcgattt ctagtttgat
     5641 cacagttgat tttgttaagt gatcggtttg atccaaacgg actttcgctg ctgattcatc
     5701 gatcaaatca attgctttat cgggtagttg acgagaagtg atataacgaa cagaaagatt
     5761 gactgctgct cgtacagctt catctgtgat ctccactcca tggtgctctt catatcttgt
     5821 acgtaatcct tgaagaatca cttctgcttc ttcaggagtt ggctcatcta cttgaatgcg
     5881 agcaaaacgt cgctctaatg cagaatcttt ttcgatatat ttttgatatt catctagggt
     5941 cgttgctccg atcgtttgta attctcctcg agctaacgcc ggtttcaaga tattcgaagc
     6001 atcaattgct ccttctgctc cacctgcacc aattaaggta tgcaattcat caatgaataa
     6061 gattacttga ccatcattat agatttcgtc gatgaccttt ttcattcgat cttcaaattc
     6121 accgcgatat ttcgtaccag caaccaaaga tcccatatca agcatcatca ggcgcttttc
     6181 ttgcatgtct tctggcactt cacctaaaat gattttttga gctaaccctt cagcaatggc
     6241 tgttttgcct acaccaggtt cacccaccag tacagggtta ttctttgtcc gtcggctaag
     6301 aatctggata agccgtttca cttctctcga acgaccaaca actgggtcca gcttgttttc
     6361 ttttgctaat ttcgtcaaat cacgtgctaa tgaatctagc gtaggtgttc cttgcggtgt
     6421 ttgccgttta tcttgtacat ttacatttct acgacgattc attccttttc cagcagaatc
     6481 accagctagc cccatttttt gtttcagaac ttgacgggct tttgaaaggc tgatacctaa
     6541 gttgatcatg attcgagtag ccatgatact ttcatctttt aataagctca tcaaaatatg
     6601 ttctgttcca actttttgag aaccagtttt cttcacttcg ctgctagcta aagcaaaaac
     6661 ttgtttcatt cttggtgaat atggaagaaa gactccttta gggtaagaac ggataccacc
     6721 ataaccaatc agatgttcaa tttcttcata aatttccgtt tcattcaaat ccatttcacg
     6781 taatactttt ccagcaattc cattttgctc gaccactaag gctagtaaaa catgttctga
     6841 actaactgat tgatgtttca accgttttgc ttcttcttgt gcaatttcta atactgcttg
     6901 ggctctttca gtaaaaagtt cttccatcta atctcacttc ccatcttcat aacttaaacg
     6961 ttccagaaat gctcggagaa tccgagcacg tgtatgatct tcatattcat tgaaattcaa
     7021 tgtgtttttt gcaattgcac tcaacatcaa gtttccttct ttttttgtaa ttatttggtc
     7081 ttcataaagt ttttgaataa tagcaaaagc atttttctca ctgattgtat catcaaataa
     7141 ctgatttatc tgctcaagta attgtttttt atctgaaatc cttacttttg caattcgtat
     7201 ataaccacca ccaccacgtt tgctttctac tagataacca cgttggatgg taaaacgggt
     7261 attaatcaca tagttgattt gtgaaggaac acagttaaag aggtctgcca tttcaatcct
     7321 tcgaatctcg atcatttcac tattttccag aattttcttt atatatgatt caattaaatc
     7381 cgaggtattc tgatgtgcca tcttattcat tccctttgac taatattgac cttaattata
     7441 acgaatttga taatagaaag aaagaagaac gctttttgtt aaataaatcc tttagaatca
     7501 acaaaaaaaa aatacggaat atactattcc gtatcgacgc gcccaagagg agtcgaaccc
     7561 ctaacctttt gatccgtagt caaacactct atccagttga gctatgggcg catattcaat
     7621 ttaaaaaaat tataaatcat ttgaaaacaa aaagcaagat aaaaaaaatc gggaagacag
     7681 gattcgaacc tgcgacccct tggtcccaaa ccaagtgctc taccaagctg agctacttcc
     7741 cgtttaaaaa ataaaaaaga c
//
LOCUS       DACBZK010000094         7382 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.098, whole genome shotgun sequence.
ACCESSION   DACBZK010000094 DACBZK010000000
VERSION     DACBZK010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7382
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.098"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(31..732)
                     /locus_tag="IVD66_002445"
     CDS             complement(31..732)
                     /locus_tag="IVD66_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAP6146623.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(748..1188)
                     /locus_tag="IVD66_002446"
     CDS             complement(748..1188)
                     /locus_tag="IVD66_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAP6146624.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(1188..1763)
                     /locus_tag="IVD66_002447"
     CDS             complement(1188..1763)
                     /locus_tag="IVD66_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HAP6146625.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(2611..3090)
                     /locus_tag="IVD66_002448"
                     /pseudo
     CDS             complement(2611..3090)
                     /locus_tag="IVD66_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015510350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(3249..3950)
                     /locus_tag="IVD66_002449"
     CDS             complement(3249..3950)
                     /locus_tag="IVD66_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6146626.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(4058..5467)
                     /locus_tag="IVD66_002450"
     CDS             complement(4058..5467)
                     /locus_tag="IVD66_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HAP6146627.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(5515..7380)
                     /locus_tag="IVD66_002451"
     CDS             complement(5515..7380)
                     /locus_tag="IVD66_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6146628.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
BASE COUNT         2110 a         1644 c         1229 g         2399 t
ORIGIN      
        1 ttttctttcc cgtcgtttgg ttttttattt ttagcctaat tcttgacctt ttgcatgctg
       61 gttatccgta aaatattttc cagcaggctt tccttccaat tcagctaatt tttcttggat
      121 ctgacggatc accttttttg catcttctgg attttctaca aaatcgaatt tatccccatc
      181 cacttgtatt ttaggacata catcaaaatc ttcataccat tgattatagc gggtgttcaa
      241 cgtttcataa taggtatata acgtctcatc gctttctagc tgttcatagt cacgcccacg
      301 ttttttgata cgttctagca tcgtgtccaa agaaactttg atatggacca tcaaatcagg
      361 ccgttttttt ggagcaacat catctaactc gtttagcatc gtatctaata agctatcgta
      421 ctgctgtact tcgatatccg ttacccgacc taaatcagcg tttagatgga acaacaggct
      481 atcttcatag atggatcggt ctagcacatt gtcatcgttc actaaagcat ttttcattgc
      541 taaaaatcgc ttgttcaaaa agaagatttg caataaaaaa gcgtactgct caggatttga
      601 ataaaagagc ggcaatactt cgttatcttc gacattttca taaaatggtt tagaatcaat
      661 ctcttttgca agcatatccg tcaaactgct cttacctgca ccaatcgttc ctgaaatcaa
      721 aatcactgac atacaaccct tcctcttcta taagtactcg cctacgtaag tttcaacagg
      781 caatgtttca aaatcatatt cacgtacagc ttggtctgat tttaaatacg tatggagact
      841 ttgtgtaatc atcaagttcg taggtaccgt ctcttcttgt acaatgatca tcggtttttt
      901 caacatagtt gccacaccta attcgtaagc cgttcctgga tcgattgttt gatgctcaaa
      961 gtcaaggata gcaacaacaa attctgcatt tgtcagttct tccatatctt tttcgtatac
     1021 ttcctgcgcc catccagcgc tgaatagttc ataattgctt tcttggtgat gacgtggaga
     1081 gtagaaactt gtgactgttt tgttttcctc caacgctttt tcgatacgac ttactcgatc
     1141 gatttgctcc tctgaaaaaa atggtcctgc taaatatatt tgactcatta ttttgcctcc
     1201 ttcaataata actgattttt aatagatact gctcgtaatt cattgaccag ttccaatgga
     1261 ttgttggaaa agattacttg atccaaccat tttttatcca taaaatcctc ttttgcaaaa
     1321 gtttctaata attgttgcaa gccgctgtaa taaccgccaa tattcaatat tccgattggc
     1381 ttgtcgggcg tcagaccgat tgctatccaa gaaagaagtt gtgagaattc ctccaatgta
     1441 cctagacctc cagggaaaac gaggacagca tctccctttt caaataataa tacctttctt
     1501 tcatcgatcg tttctgtagg aataaatgta gtaacatctt ttccaggcaa ttcagtttca
     1561 aaaagcccat tcggatagat acctgtgact tttccgttat tttccagtac tgttttacta
     1621 atcactccca taatcccgga gtatgaacca ccgtaaacca gttcgatttc ttcttgtgcc
     1681 atgtattttc ctaacgtttg cgcaataaat ttgtaacttt ctttattacc aaaacgggaa
     1741 ccgcaaaaaa cagtaagttt cataaaaaaa cactccctaa ctcaaaagtc tatcttcatt
     1801 ctacacgtgt ttttttaaaa taaaagacta gattttgtag ttttttagtg gtatatagga
     1861 tagacgccac tatatatagt atttagaaaa aaatcatttt tcagccattt tatagataaa
     1921 acaaaaataa ataacgtgtt ttcatcgata tgaaatgact tacttataga agatactggg
     1981 atttcgtcct atatgccaat aacgtgtatt attttaaaca acaaatactt gtttctttta
     2041 ttaacgaaaa aatcattttg ttctcgtgtt atgtttcact gataaatgat gtttctctaa
     2101 ataaaaaagc cgacgaacta aacgatcaaa atttgatcat ttttgttcat cagcttctcc
     2161 taaaaatctt tttgttaacg ataaatagct ggatttgtaa aaatatcact tgaatcgtca
     2221 ctgctggaag aaaattcagt gataaccgca cctgttgcgc ctgcctggaa ctagtgtttg
     2281 atattgggct cgaacgtgta ctgatctcta gcatgaagaa taatttcttt ttttactgta
     2341 taataacttt ctttcctttt tggaatagta caggaaagtt tttttgtttc ctttccttcg
     2401 acataaggta taccagaccc tttcgacaac gaaaggttct catttttcct tcatcgtcat
     2461 ttcaaggagg gtgccgatgc tctggacagt ttcgatcgct cctaaaccaa aatctgtata
     2521 ttcgattctt tctaactctg attctttcat accattcctg tctcaaggta catctattgt
     2581 acttttttct tgtaatccat tctgcctctc ctaactaatt gtcaaatcat cccaagatat
     2641 gtcttcttcc tctttttctt cttggatgat ttctgcattc ggatctactg gttttttcaa
     2701 taataaaatg gttattcctg tgacaaaaga accagctaac aatgcaccaa tgaatgccca
     2761 tggtctggtc atcgtagcga ctgcaaacat tcccgatgcc ggaatacggc tatctgcgcc
     2821 ccaaaacatg cttaatccgc cacctactgt cccaccgact cccgttgcta tgacattgcg
     2881 tgccaagtcg ttcaatacga tagggaaaca tccctctgtg atctgacaga tccccatagg
     2941 aaaagcggtc ttcaatgtat cgatttcttg acgattgagt atatttttac gaatgatttt
     3001 ccctaagaaa taagcgatcg tcaagccgaa tggggttacc atcgaagcta aaatcaatac
     3061 agtgattggt tcatagattc cttctgaaaa tcgtgccaca cccccttatc cagaataaat
     3121 ggtaatccag aaacagccgt gtatctgcgg taataagcct aaccaaacga aaaatatgag
     3181 aagctatttt tgtttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct
     3241 ttttttattt atgtttcata atcaatatgg taaggatgca gctccgtatg gtagaccgcc
     3301 tccgaatatt caatcatttc cccaatttgc gtagacgatt tccgtatccg tttgatgccg
     3361 atctgtgcgt ctgttttcag aattccttgt tcttcttctg ttaaaaatac tgccgagaaa
     3421 tcatcagaaa atgagtcaat agtatatcct tttttcgtca gcaaacgata caaagattct
     3481 ttgccaaatt cttctctgct gaattgcatc atttcttgtg gaagataatg aacaaaataa
     3541 atataaggct gattgttcaa ataatataag cgcttaaaac aaacagcttg ctcaccgaaa
     3601 aaggaaaaca aaggatcttc cttctttata tggaccaatt gcaaatccag cgtttctttc
     3661 cggacttcat atcgggagtt ctccaagatt tgcgtaaagc ttgccgcttt ggataatcga
     3721 ttgtaaggac gattgcttag aaccgtcgtc ccacgaccac ttttctttgc gacatattca
     3781 tctgatgcca gcagttcgat tgcctttcgg acagtgattt tgctgacttg aaacagttct
     3841 tctaattcac tttctgtcgg caacatcgaa ccgactggat attttcctga gaaaatatct
     3901 tctttaattt tatctgcgac ttccaagtat agtacacgtg tccttttcat aacgtcaccc
     3961 tttgctttac tattactaaa agaatagcac ataaaaaata aaaaaagaac acaaatcaca
     4021 tgtgagaagt gtgttctttt tcattcagct gctttaatta caagtttacg ccatttgagg
     4081 caattacttc tttataccaa tcaaaagatt ttttctttga tcgattcagt gtcccatttc
     4141 cttcatcgtc tagatccaca tagataaagc cgtaacgttt actcatttct cctgttgatg
     4201 cactgacaag atcgatacat ccccaaggcg tatagcccat caaatctaca ccgtctgcta
     4261 ctgcattagc catcgcttcg atatgacgac gtaaataatc gatccgataa tcatcaataa
     4321 tcgtgccatc ctcttccata tgatcaatgg ctccaagacc gttttcaaca atgaataatg
     4381 gtttctggta acgattgtat aattcattca atgcgattct cagcccttct ggatcgatct
     4441 gccagcccca ttcacttgcc tcaagaaacg gattttttac tcctcccagc aagttccctt
     4501 ctgaagttgc tgcttgtgga tcagtctcat tgattgccgt agacatataa taactaaatc
     4561 cgatgtagtc cactggatat tcttttagca actggaagtc tttttccgtt tgctctaatt
     4621 tttccggatc gactccatat tttttatggg tacgcgctgt gtatgcaggg tattctccac
     4681 gtacttggac atccgtgcag aaaaaattga attcttggtt ttggatcatt gttgctgcct
     4741 gattgactgg attggcatcg atgctgtaag ttgttgcata gataatcatg cagccgattt
     4801 ggatatccga acgcaattcg tggccgattt ttacggcttt gctacttgca acgaattgat
     4861 tatgccatgc ttggaaaata ttttggtact ctcctgctcc attgcttttt actaatcctt
     4921 gacttaaagc tggaaagtga aaggccgaat tgatttcatt gaaagtcatc caatatttga
     4981 ctttactgct gtatctctct aatactgtct gagcaaatcg ttcatagaag tcgatcagtt
     5041 ttcgattttt ccagccaccg tattcttttg ccaaatgaag aggcatttcg taatgagaaa
     5101 tcgtgatcac aggttcaata tcatatttta agcactcatc aatcagctga tcataaaatt
     5161 ctaatcccgc ttcgttagga gtaccttcgt ctccatttgg aaaaattcgt gtccaggcaa
     5221 tcgaaaaacg ataacatttg aatcccattt ccgcaaacaa ggcaagatct tctttgaaac
     5281 gatcgtaatg atcgattcct cgatgattcg ggtaaatata tttttcttga tcaatcgtcc
     5341 agtcaaattc ttcactgccg ataatcgcaa agcgctgctt acctccaggc atagcatctg
     5401 caacggatag tccttttccg tctcgatcat aagccccttc taattgattt ggcagcagtt
     5461 gctccacccc ataaaaattt ttctgaaaaa cgtgattgca tcctgatttc ctccttattt
     5521 tacaattgcc agaacatctt cgtttgcaat aatctctttt tggtctaatt caagtatatc
     5581 ggcaaatgca tcagtattcg taatgacaac tggagtgatt acgctatagc cagctgctct
     5641 aattgcttcg atgtcaaaac gaatcaataa atctcctgct ttgacgagat ccccttgttt
     5701 gactaagatc tcaaagccat tcccatttaa ttctactgta tccatcccga tatgaatcaa
     5761 aatctccgct ccgtcagtcg ttgtgatccc tacagcatgt ccagttggaa aaatagtcgt
     5821 gatctctccg tctgcaggtg caactagttc tcctacttct ggatcaatag cgataccttt
     5881 tcccatcacg ccagaagaaa aaacttggtc tggtacttca ctcaatggca gtactttacc
     5941 cgttaaagga ctttttaagg tatgccgtgc tgaagtaatc ggttctcctg cattcgcatg
     6001 tttgttttct aattgattgt cttgtgtttg ttcgtcaaat cctaaaatca atgtacctac
     6061 gaatgcaaga acaaaagcaa ttcctgtagc tattactgct actgtcacat ttgactctac
     6121 accatccacc gtattaatga aagtcggaat cgtcaataag ctgaccaaac tgctggagaa
     6181 agcttttact ccggaaaatc cgataatagc tccaccaata cctccagaaa tacaagcggc
     6241 aatgaatggt ttcttcaaag gtaatgtcac accatacaca gttggttcag tgattccaaa
     6301 taacgaagtc actgtagaag aaatccctaa tgctcgaagt ttcgtatctt ttgttcgcaa
     6361 tgctacagct aaagcagccc caccttgtgc caagatggct ggaagaagca ttggcatcaa
     6421 tacatcaaac ccatattgtt cgatattcaa aaacatgatc ggtacgaatc cccaatgcat
     6481 gccgaacatc acgaatactt gccataaact tcccatgatt agacctgcta cgattggact
     6541 aaatccataa atcgagttga agagaccgcc taaagcatta ccggcaaccg tcccgattgg
     6601 tcctaaagca agaaatgtta atggaaccat cactactaaa acgacaagcg gaactaaaat
     6661 catttgcaga aattgcggaa tcactttttt tacgaatggc tctaatttac tttgaaccca
     6721 tacggctaga atgattggta tgacagaaga agtataacca gatggtgaaa gaatcactgg
     6781 gatcccaaag aaactgatag cttctcccgc accagcaact gctgtgatag ctggatacac
     6841 aagtgccata gcaattgcta ctgctaaaaa ctggttggct ttgaactttt tagctgctgt
     6901 aaaagcaagc atgacaggta agaaggtaaa gacaccatct gctgcagcaa acaatatttg
     6961 ataagtaccg ctatcagctg tcagccagcc catcaccgtt gccaatgata agaatccttt
     7021 caataccccg gcggctgcca tcgcccctag aaaaggtgta aatatactag agataatatc
     7081 gatcagacga ttcaaaatat ttttggactc ttcttttcca tcctccgaaa ctgcaagacc
     7141 ttcctcatcc acgatcgatt gataaacatc tgctacatta ctgccaatca ctacttgata
     7201 ctgaccgcca ctttgtacga cttggatcac gtccgggtct tcttttaact tttgcgtatc
     7261 tgctaaagat tcatctttta atctgaatcg caaccgcgta gcacaatgta ctaaactttt
     7321 gacattcttt tgtcctccta ccgcttccca tacacgacga ccaactgctt gattatccat
     7381 tg
//
LOCUS       DACBZK010000095         7346 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.099, whole genome shotgun sequence.
ACCESSION   DACBZK010000095 DACBZK010000000
VERSION     DACBZK010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.099"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..185
                     /locus_tag="IVD66_002452"
     CDS             <1..185
                     /locus_tag="IVD66_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAP6146629.1"
                     /translation="NMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMG
                     ISYDEYQKLEMGKKIV"
     gene            complement(639..2330)
                     /locus_tag="IVD66_002453"
     CDS             complement(639..2330)
                     /locus_tag="IVD66_002453"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HAP6146630.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(2750..3697)
                     /gene="arcC"
                     /locus_tag="IVD66_002454"
     CDS             complement(2750..3697)
                     /gene="arcC"
                     /locus_tag="IVD66_002454"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HAP6146631.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(3812..4831)
                     /gene="argF"
                     /locus_tag="IVD66_002455"
     CDS             complement(3812..4831)
                     /gene="argF"
                     /locus_tag="IVD66_002455"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HAP6146632.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(4922..6151)
                     /gene="arcA"
                     /locus_tag="IVD66_002456"
     CDS             complement(4922..6151)
                     /gene="arcA"
                     /locus_tag="IVD66_002456"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HAP6146633.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            6612..7313
                     /locus_tag="IVD66_002457"
     CDS             6612..7313
                     /locus_tag="IVD66_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP6146634.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
BASE COUNT         2108 a         1488 c         1278 g         2472 t
ORIGIN      
        1 aaaacatgca gtacttcaaa aacaagtcgg ttgatgaagt aatcaaagtc ggagatacgg
       61 tctcagatat ccaggaaggg aaaaatgccg gagtgttgac agtaggtgta attgaaggta
      121 gttcgctaat ggggatttct tatgatgagt accaaaaatt agagatgggg aaaaagatcg
      181 tttaaaacag tctgttgctc ttagattcca acaagccggc gctgatattt gtgtaaacaa
      241 tttaaaagag ttaacagaat acattttgta cgctgacaag aatccagaat gacttttata
      301 caaaataaga ggttgtgaaa aagctgtcct gtatcaagta ataaaaacag ccaagcaaaa
      361 atagctcctc atatttttcg tttggttagg cttattaccg cagatgcaag cttttgaaca
      421 ccgtttattc gaaaaaaaaa agggagctgt gacacgactt ttgtcacagt ccccttattt
      481 gcaaacaaac agtgtttaag agacaacctc tccactaaac ggtgttcatt cagctgactc
      541 tcggtatttg ctcaaaaaac gataaaattt gaaaagctat tttctctttt gtttctctaa
      601 tactcggatc agaacgctga tttcacattc tctttttctt acatcttatc tggtgcatga
      661 agtcctagca aacgaaggtc ttctttcaat aatacagtca ctgcataaac tagagctaag
      721 cgtgcttctt tttgttcatc atcagctaaa atcttcgtat gagcatagta tttgttgaat
      781 gcttgtgcta atttgattgc atgtttcgca atcactgacg gttcgtattt ttccccagca
      841 gacaagaccg tttcagggta tttttgaact aatttaacca cttcccagct ggtatcgtca
      901 ttcaatgcat agtctgctgt ttctgaaggg acaaatcctg ctttttccaa caggctgact
      961 gcacgagcat gtgtatattg cacataaggt ccagtttctc cttcaaatcg aacaacttct
     1021 tccaggttaa agtcaaatgt attcagtcga tcgtttttca aatcgtggaa aatgactgcc
     1081 ccaaccccaa cttgtttagc tacagcatct ttgttttcca aatcagggtt tttctcgctg
     1141 atttgttctt tagcagattg gattgcttca tttaatactt cttctaataa gacgatcttt
     1201 cctttacgag ttgataattt tttaccacct tgcgtgatca aaccaaatgg aatatggtgc
     1261 atgtcgtcag accagtcaaa gcccatttcc ttcaagacag ctttcaactg tttaaaatga
     1321 tagctttgtt cattccctac tacatataga gattgtttga agtcgtaagt acgtttacgg
     1381 tacaatgcag cagctaagtc acgtgtaatg tatagtgtcg caccgtctga cttcttaatc
     1441 aacgctggat tcaggtcata agcagatagg tcaacgatct ctgcaccttt atcctcgttc
     1501 agcaaatgtt tttcttctaa aagtttgacg atttcatcca tcttgtcatt gtagaaagct
     1561 tcaccgttca acgaatcgaa acgtacttcc agcagatcat agattttatt gaattctttc
     1621 atcgattcat cacggaacca ttgccataat tgaatagcct ctttatcgcc ttcttccaga
     1681 cgtttgaacc aagcacgagc ttcttcattt aattctggtt ctgtttcagc tacttcatgg
     1741 aattggacgt ataaacgaag caattcattg attggttctg ctttaacagc ttcttctgta
     1801 ccccattttt tgtaagcgac gatcagtttt ccaaactgtg ttccccagtc acctaaatgg
     1861 ttgatgcgga ttggctgata accgattttt tccataatga aaccgatcga attaccgata
     1921 actgtcgaac gcaaatgtcc cattgagatt ggtttggcaa tattaggaga agacatgtcg
     1981 attggtactg ttccttgatt cccgatgttg ctatccccat aatgttcttt ttctttcact
     2041 acggtttgca aaactttttt gctgataagt tctttattca tgaaaaagtt caagtaaggt
     2101 ccgacaactt cgattttttc aaagttggca gaatcgattt tttctgctaa atctgcagcg
     2161 atttgctgtg gcgcttttcg gtaaactttt gctaatgaaa aggctggaaa tgcaacatct
     2221 ccgtgttcag ctgattttgg attttctagt aattgctcga cttgttccag tgttaaatca
     2281 tctttgacag cgtcatagac agcttttgcg acaagatctt tattattcat ctttattcct
     2341 cctaaagtgt tcccttgatt gttaaacaaa aaaaatctct agcgacggca tacttagtat
     2401 gccatcacta gagacgagat ttcccgcggt accactccaa ttgtcctaaa aaaggaccag
     2461 ctccatctga tatcggtaga cgaccgtctg tttaaaacag aattctccaa gtgcgcttcg
     2521 ttgtatcttc ttcattcggc ttccaccact tccgaattcg ctagccaaga atgatacaag
     2581 tactctcttg ttcaacaaat cttagtctta ttaaactttc ttgaattata tcagaaaaaa
     2641 aaacgaaagg ctagtcgttt cataaaaaaa aaatccagat ggcctaaagg agaagaaata
     2701 ccacctggat agctataaat catttcgtaa atacgaaaga cttaacaaat taatcagcta
     2761 cgataatcgt tccttcttca gaagctaaaa gattctcgat attttctaaa gaagtgatga
     2821 ttgccttagc gtttggtttt gcttcaacaa atgcaatagc tgcttctact ttcggaagca
     2881 tgcttcctgg agcgaattgc ttttcatcaa tgtattgttt catttctgaa acagtaacag
     2941 tttctaattt cttttgatct ggtttttggt aattgacata cacattgtct actcctgtca
     3001 atacgatcag caaatccgca tcgatgattt cggctaattt ttctgaagca aaatctttat
     3061 cgattacggc ttctcgtcct tctaatccag tagctgtttc tacaacagga atcccaccgc
     3121 caccaacaga gactgtgata actccttgat cgaccagcgt ttcgatgaca cgtgcttctt
     3181 taatcgagat gggtttaggg gaagcgacta cttttctcca tccacgtcca gcatcttctt
     3241 tgaatgtcac agtggagtca gcattcattt gttctttggc ttcttcttcc gtgtagaatg
     3301 gaccgactgg tttacttgga tttttgaatg aaggatcatt ttcatccaca ataacttgag
     3361 tgactaaaga aaccacatct ttatcgatcc ctttttcctt cagtacttcg cccatggcgt
     3421 tttgtaacca gtaaccgata gatccttctg tcattgcaac acatgtatct aaaggcattg
     3481 ccggtgtttt ctcagaatca gcagcttgct gctgaatcaa taggttaccg acttgcggac
     3541 catttccgtg ggagatgatc aattcatctc cttgttcgat aaatttcact aaatactttg
     3601 ctgtttccat taacgcttct tgttgggctt ttgcacttgc atccgtagac aagatggcat
     3661 tgccccctaa agcgacaact acttttcgtt tggccatttc attcgtcctt tcttcagttc
     3721 taccgaattt tctagataac aaaacgagcc agcgttttgt gattttccct caatgctgac
     3781 tcgttttttc gtgagatgaa tgtggttatg cttaaacgcg agggataaac aagttaccta
     3841 atgttgctgc catgatcgct ttgattgagt gcatacgatt ttctgcttgg tcaaattgac
     3901 gagcatattt gctgcggaag acttcatctg ttacttccat ttcagtgatg ccaaagcgtt
     3961 ctttcatttg ttcaccgtaa acagtgtttg tatcatggaa agctggcaag cagtgcaaga
     4021 agatcaaacg atctgtgttg tgtgtttttt ctaccatttc catattgatt tggtaaggtt
     4081 tcaacaattt gatacgttct tcgaatttat cttcttcacc cattgatacc catacatcag
     4141 aataaaggac gtctgctccg tctacacctt tatcaacatc gtcggtaatc atcaattgtg
     4201 caccggattt ttcagcaaag ccttctgcca ttttgacgat ttcttcttca ggttgtaatt
     4261 cttttggtgc aacgatacgc atattcgctc ctaaaattgc acctgtgact aataaagagt
     4321 tagccatatt gtttcgacca tctccgcagt aagcaacagt gataccttct actgttccaa
     4381 agttttcttg gatagttaaa aagtcagcga tcatttgtgt tggatgccat tcatcagtca
     4441 agccattcca aactggaaca ccagagaatt ctgctagttc ctctaccatt ttttgactga
     4501 atccacggaa ttcgattccg tcaaacatac gtcctagtac tttagctgta tcttctgtgg
     4561 attctttttt acctaattgg atatcatttg cacctagata ttcaggatgt gcacctagat
     4621 cgatcgctgc agtagtaaat gcagaacgag tacgtgtaga tgttttttca aataaaagcg
     4681 caatattttt tccttctaga tagtgatgtg ggataccacg ttttttcaag tctttcaagt
     4741 gttctgaaaa atcgatcaaa tattgtaatt cttcttttgt aaagtctttt tctgctaata
     4801 agcttcttcc ttggaatact gattctttca tattaaacat tctcctttag attgttttta
     4861 tttaagatta aagaggaaat cccgacggca gctgacagta agactgccgt caggaaacaa
     4921 attacttcaa gtcttcacgg acaagtggtt ggctcatgca gcgtggacca ccacgacctc
     4981 gtgacaattc acttgaattg atttctaaca ctttgatgcc atagctacga agcaattcgt
     5041 tcgatacata atttcggtta taagtgacta caacacctgg agcgattgcc aatgtgtttg
     5101 atccatcatt ccattgttct cgaggtgcaa cgatctcatc tccattacca gttgggatca
     5161 gtacaagatc atctaatcca agagcagctt tcatcgtttc gtgtaagtta tctgaatgag
     5221 taatcttgat atcatcacca tctggttcga ttgtaaagac atccatctta ccgtctttac
     5281 tttgaattgc tggatggata gtgaatttat cgtgatctac cattgtaaat acggtatcca
     5341 aatgcatcat tgcacggttg ttcggaattt tgattgccaa cactttttca aatcctgaat
     5401 tttttgcgaa taggtggcgt gctaattttt ctaaagcttt cgcattagtt cgttgagaaa
     5461 tcccaacagc tactacttta tcgcttaaga tcaattcgtc tccgccttcg atatgatctg
     5521 gattttcacg atccaaccat acttcgattc ctttatttgc aaatcttgga tgatgtttca
     5581 aaatatattc tgtaaacatc gattcacgac gacgtgcttc aaaagtcatc ttattgactg
     5641 tcatcccatt tcccattgat gcggaagggt cgcgtgtaaa gtacaagttt ggcattgggt
     5701 ccatgtaaaa tggatagtca tcgtctgctg acagatcata tagactgcta gaacgtactt
     5761 cgatatcttt tgtacgaacc ccagccatga ttttatctac catttcttgc gtttccattg
     5821 atagaaggaa ctcatgaaga ccctctctta cagcattcga tgcaatatga gattcatcca
     5881 acattttatt caagaattgt tctttgacat tgcctgcgtc aatcgcttct gccgctaatt
     5941 tttccaagta aagagtctcg acgccttcat tttgcaatgt cttcgcaaag ttgtcatgtt
     6001 cttcttgagc aatcggaaga tatggaatat catcgaacaa cagacgatcc ataatatctg
     6061 gtgtcaaatt ttccacttct tgtccaggcc gtttcagtaa aactgtcttt aatttcccta
     6121 tttcagagaa aacgtgaata ggtttatcca tgttgtgttg cctccttctt tttgattaca
     6181 tgtataggat atcctccttt tgtaatcact ttcataattt tgtctcattc aaaatgagac
     6241 attcctcaca ttaatattcg ataattaaat aattaaacgt ttttctattt ttaagcgtaa
     6301 tttattcatt ttttattctg tatacacttt caaaaaaata tttattcatt gaaaaaattt
     6361 ttttgaataa attaaaaaaa taaattatat tatcgttgtt agcgtttact atatgtatta
     6421 ttgttgtttt ttatacacaa atcattcgct tcaaaacaaa ttattcaata ccattgtata
     6481 ttttttacat aataacaaat tatatttgta aagtattaaa acttgtttct aatgttggta
     6541 tgttaaaact ttacaaattc tttaaaaaaa gtgacaataa atatagtgaa caataaggag
     6601 aggacttttt aatgcgtgtt aataaaatcg attttcactt ttcaaaactc agatatcaac
     6661 ctgattttga acatttctcg gatgaagagt tccaacagat caaggaacat actgttcttc
     6721 gttcttataa aaaaggacag atccttttcg acgatggtga tcccagacaa cggttgtata
     6781 tcttgaccaa aggactcgtt cgtttagaac gttatgatga aagtgcaact tattactact
     6841 atgactatgt gaatacaaat aacctttttc ctatgtcagg aatgtttgga gaagagacct
     6901 acacttatac agctcaagcg atgactgata ttgaaacatt ctaccttcct gtttcctact
     6961 atgaaaaatt agcacgaaaa aatcccgaac agttgatcta tatgatacaa aaaatttcta
     7021 aagtagttga aatacatgaa ttgcgtatcc aaatcggatt gacctctagc gcctttgacc
     7081 gggtaaaaca aaatttattc attttgaaag aagaattggg cgtaccaaca aaagatggtc
     7141 atatcaccat tccttatccg atcaccttaa aagaattagc agtgaatagc ggcacgacac
     7201 gtgaaactgc tggacaagta atcaaacaac tacgtgattc cgggctgtta gattatgaca
     7261 aaaagcgttt tactttctgt aagacagcta ctactccagc tatgagagaa taacgcgaac
     7321 aaaaataagc agtgaccctg ataaat
//
LOCUS       DACBZK010000096         7317 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.100, whole genome shotgun sequence.
ACCESSION   DACBZK010000096 DACBZK010000000
VERSION     DACBZK010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.100"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(153..1238)
                     /locus_tag="IVD66_002458"
     CDS             complement(153..1238)
                     /locus_tag="IVD66_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepA"
                     /protein_id="HAP6146635.1"
                     /translation="MSTEIQSQKMIIKNWGYKATNVYIEKYYKFPSFLIQNSKYSKMK
                     DSSKIAYMLFKNEFRRALHEKWIDDDGLLYLEFTQADLMDKLNCYQGKVKTILNELET
                     YNLISVVKGEFNPKTKKNEKNKYYLLQPEISADDLFIQNSFDDDLSQTIDKSTSSRNA
                     EIARREETAKTLDNTGNAEIARREKTAETLDNTGNAEIAQDYYINKSLDTKRHLKDTE
                     TDQLQNQVLLDNFVEIMKEDSINTFVPEKVLSLIKTFSNTYEEAQQTVTTIHNAKHKA
                     EELEKTVVVYEELESYGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFIEK
                     AIAAKLANEQRETFNELPTVSTENWLE"
     gene            complement(1558..1965)
                     /locus_tag="IVD66_002459"
     CDS             complement(1558..1965)
                     /locus_tag="IVD66_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146636.1"
                     /translation="MPKDFDIPKMMENGEFEPLLPNNKRQDVKISGEYNFSNSALSNT
                     KNITLKKRGRPVSIPDKRNKVSVPKKISPALNSKLSILQDYMTELQSEKGRISFEKIV
                     NTLADSYIQHRLGVAKEEHIREEIQEEFEKLPK"
     gene            complement(1984..2802)
                     /locus_tag="IVD66_002460"
     CDS             complement(1984..2802)
                     /locus_tag="IVD66_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP6146637.1"
                     /translation="MDTFQGTTFTVGNFKGGVGKTKIVSMLAYDNAMIRNRKTLIIDL
                     DPQANLTQVIARTFGITDIKTTITNGVANGELASSIIKVNENLDLLACDTSFRSFSAF
                     ANKHENELDQVTVLKKLLLPIKNNYQEIFIDVPPTISEFSDNAMAASDYSIISFQTAE
                     ESLEGVNKYVNYQKFMVDRYDLDLQIIDIVPCMVEPNDDFDEEILEEAIEKYGTVVSK
                     NLIHYQKRLRRYSKIGIHLRKYKNGNFDQWDYKAHQVFINILAELDARQEFLNK"
     gene            complement(3028..3321)
                     /locus_tag="IVD66_002461"
     CDS             complement(3028..3321)
                     /locus_tag="IVD66_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAP6146638.1"
                     /translation="MSINTFVYSHPINVYIIKYLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSMNMTDVYEKLLILENEYDQFTSNQQRKVKKQID"
     gene            complement(3457..3636)
                     /locus_tag="IVD66_002462"
     CDS             complement(3457..3636)
                     /locus_tag="IVD66_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146639.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLFI"
     gene            complement(3633..3983)
                     /locus_tag="IVD66_002463"
     CDS             complement(3633..3983)
                     /locus_tag="IVD66_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146640.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRANQNLAKEQMRTE
                     EIAEILNASVIKNRSVCIQKEERNAEGYYPDDIVGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(3976..5301)
                     /locus_tag="IVD66_002464"
     CDS             complement(3976..5301)
                     /locus_tag="IVD66_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAP6146641.1"
                     /translation="MLDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKNLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYQNVPDKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIKDLANWNPYTIKSRLGVIGLQLYFHANGIDRTDIAIAPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHHCKTGCVHLHIGTSILETRPGFSHQMKI
                     SITDNTRELQDYCLFLFNKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDDEK
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            complement(5410..5613)
                     /locus_tag="IVD66_002465"
     CDS             complement(5410..5613)
                     /locus_tag="IVD66_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAP6146642.1"
                     /translation="MKEQQLGYTLWGRPLYGLERRTAVSIDCACGELIQLNIQTKQYN
                     CKNCGNCYQFIDQDFQLLNEKNK"
     gene            complement(5773..6348)
                     /locus_tag="IVD66_002466"
     CDS             complement(5773..6348)
                     /locus_tag="IVD66_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6146643.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKLFAKKNNPNFKEGRPKATITPKKRHAYELI
                     TSGKSYKEVEAITGFSRSTLFRIKKQIEASE"
     gene            complement(6364..6969)
                     /locus_tag="IVD66_002467"
     CDS             complement(6364..6969)
                     /locus_tag="IVD66_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein Fic"
                     /protein_id="HAP6146644.1"
                     /translation="MILENKLGLTNQVELAKAEEKLSKQKAKELYDSGKINEIEVGTF
                     KGLSEIHDFLFSEIYDFAGKIRTVNIAKGNFRFAPVMYLEQSLNHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT         2131 a         1346 c         1077 g         2763 t
ORIGIN      
        1 ttaaaaccta cgtttgtgat tgttttcata aacttttaat ctaaaaactc cggaataata
       61 actatttatt tgtaacattt gtaataaaat taaaattata aaaaagttct aatttaaaat
      121 tgatcatttt tatagtgatc gctttttatc aactactcta gccaattttc cgtactaact
      181 gttggtaatt cgttaaatgt ttctctttgt tcgtttgcaa gctttgccgc aatagctttt
      241 tcaataaacc agttttttac atacacaaaa atcaaattct gcaaattatt tactttctca
      301 gtcttttgtt tttgataagc tttcagcaac gtcatatata atcctttatc cgcatcaatt
      361 ccgtaagatt caagttcttc atacacaact accgtcttct caagttcctc ggctttatgt
      421 tttgcgttgt gtattgtggt gacggtttgt tgggcttctt cgtaagtgtt agaaaatgtt
      481 tttatcaagc ttaatacctt ttctggtaca aatgtgttta tgctgtcttc tttcatgatt
      541 tcaacgaagt tatctagcaa aacttgattt tgtaattggt ctgtttcagt gtcttttaag
      601 tgtcttttag tgtctaaaga tttattaata taataatctt gtgcgatttc cgcatttcca
      661 gtgttatcaa gggtttcagc tgttttttct cgacgtgcga tttccgcatt tccagtatta
      721 tcaagggttt tagcagtttc ctctcgacgt gcgatttccg cattccgaga agaggttgat
      781 ttatcaatag tttggcttaa atcgtcatcg aaagaattct gaataaaaag atcatcggca
      841 cttatttcag gttgaagtaa atagtattta tttttttcat tttttttcgt ttttgggtta
      901 aattctcctt ttacgactga aatcaaatta tatgtttcta actcgtttaa aatggttttt
      961 actttgcctt ggtagcaatt taatttgtcc attaggtctg cttgtgtaaa ttccaaatat
     1021 aatagaccat catcgtcgat ccatttttca tgtaaggctc tacgaaattc atttttaaaa
     1081 agcatatagg ctatttttga gctgtctttc attttagagt atttagaatt ctgaattaaa
     1141 aaactaggaa atttataata tttttcaata taaacattcg ttgctttata tccccaattt
     1201 ttaataatca ttttttgaga ttgaatttct gtagacatta aatttctcct tcttcataga
     1261 aacttgtata tattcacgat tttcaacaag tgaactatac catgtattaa gggtgaataa
     1321 aacactttca gtatttaagg tataagttat atattaaaaa aataagtata agttatactt
     1381 taaatacaaa taatgtataa cttatacttt aaataataat tttataatgt tgatttaatc
     1441 gcaaatttac acgttgttta ttaagttata ctttaaatat ttaatgtata acttatactt
     1501 taatattcat ttatctagta taacttatac tttaattgaa taccgcatga aaaaaaatta
     1561 ttttggtaat ttttcaaact cttcttgtat ttcttctctt atgtgttctt cttttgctac
     1621 tcctagtcta tgctggatat atgagtctgc taatgtatta acaatttttt cgaaagaaat
     1681 tctccctttt tcactttgta actccgtcat atagtcttgt aaaattgaga gtttgctatt
     1741 taatgccgga gagatctttt taggaactga taccttgttt cttttatcag gaattgaaac
     1801 tggtcggcct ctttttttca atgtaatatt ttttgtgtta ctcaatgcac tattgctaaa
     1861 gttatattca ccgcttattt tcacatcttg gcgtttgtta ttgggtaata atggctcaaa
     1921 ttcgccattc tccatcattt taggaatatc aaaatcttta ggcattactt atgcaactcc
     1981 ttattattta tttaaaaact cttgtctagc atctagttct gccaaaatat ttataaatac
     2041 ttggtgtgct ttataatccc attgatcaaa atttccattt ttgtattttc ttaaatgtat
     2101 accaatttta gaataccttc tcaatctttt ttgataatga atgagatttt tggataccac
     2161 ggttccgtat ttttcaattg cttcttctag gatttcttca tcaaaatcat catttggttc
     2221 taccatacaa ggtacaatat ctataatttg caaatcaaga tcgtatctat cgaccatgaa
     2281 tttttgataa tttacatatt tgttgactcc ctctaaggat tcttcagctg tttgaaatga
     2341 aattatcgaa tagtctgaag ctgccatagc attatcggaa aattcgctaa tggttggtgg
     2401 tacatcaata aatatttctt gataattgtt ctttattgga agaagtaatt ttttcaagac
     2461 agtaacttgg tctaattcat tttcatgttt attagcaaaa gcggagaatg atcgaaaact
     2521 agtgtcacat gccagaaggt caagattttc atttacctta ataatactac ttgctaattc
     2581 tccatttgcg acaccatttg ttatagtggt tttgatatcg gttataccga aagttcttgc
     2641 tatgacttgt gttaagttcg cttgagggtc taaatcaata ataagcgttt ttctatttct
     2701 tatcattgca ttgtcataag caagcatgct gactatctta gttttaccta ctcctccttt
     2761 aaaattgcca actgtaaatg tagtcccttg aaaagtatcc atgtaaatcc tcccaatctt
     2821 taattgataa ttaaagtata acttatatat cggaaatggt caacattaaa agtataactt
     2881 aaataataat atctaaaaac gtttggatat agcggttttt aagaataaaa gtataagtta
     2941 taccctaaat atatatggta taacttatac tttaattatt taaggtataa cttatacctt
     3001 agatattgct tttcgaaaat agctattcta gtctatctgt ttctttactt ttcgctgctg
     3061 atttgaagtg aattgatcat attcattttc tagtattaat aacttttcgt atacatcggt
     3121 catattcata ctagaagcaa gacttagatc atatacaaat gaagcaggta atgattttat
     3181 tctacgttgt cgggttatcc agcttgcaac cgttccttgt gggtaggcat ataactcaca
     3241 aaattgttct acagtgattc ctaaatattt gataatgtaa acattgatcg ggtgcgagta
     3301 aacaaatgta ttgatggaca tggtgcgtaa gcctactttc ttttattatt gcgtttgcaa
     3361 taatagttta acacacgcat tattctagta tctactccta tttgtaaaaa caaaaaagga
     3421 ttcatagaga taactctata gaatccgtaa aataccttat ataaataacg ggaaaatata
     3481 aaacctaaaa ttatgataac ctgctgcagc ttctacatag aaagagaaac gctcaacacc
     3541 aacctcattt atcaaacgtt ggccataccc ccaaatctct tctgatagct gatcaaaggt
     3601 tatatacttt agctcatatt gctggataat gttcattcta atcgactcca tttattatcc
     3661 tggtaaaatt cgatatgacg tatttcgtcg tagtgaattt tgtctttgcc aacgtagatt
     3721 cccagctcat cactacctaa gatctttcca acaatatcgt ctggatagta tccttcagcg
     3781 tttcgttctt ctttttgaat acatactgat ctatttttta tgactgaagc gttcaatatt
     3841 tccgcaatct cttcagtcct catttgttcc tttgctaaat tttgatttgc acgttgctca
     3901 ttatctgcat cgatctcttc agtatgatcc gataaataga aacctgccca tttcaatcgt
     3961 cctcgatcgt tatagtcaat catttttaag cccccctgcg ccgcctgcat ggccaccaac
     4021 caacgtgctt ctagtaatac tacgagcgcc ttctaacatc gaagaagcat gtacaattga
     4081 cgtaaaacca tacttctgcc taattttatc tattattttg tctagttttt cgtcatcaat
     4141 ctgtttttgt ggatcactaa acaaatccag ctgaagcgaa tcagtataaa ctagcttgct
     4201 gtaagtgatt ccgacatggc ggacttcttg tccctcatag tatttattaa ataagaacag
     4261 acaatagtct tgtagctctc ttgtattatc tgtgatagat atcttcatct ggtgtgaaaa
     4321 ccctggtctc gtttctaaaa tcgacgttcc aatgtgtaaa tgaacacaac ctgttttaca
     4381 gtggtgttgc ctaatacgga ttgctacttg ctcagccatt tcttttacga ccagttcgat
     4441 ttcatttctt ctagtataat ctcgtggtag cacttgtgaa ttgccatatg atttttcctt
     4501 tgtcggttct ggtgcgattg ctatgtcagt tcgatcaata ccatttgcat ggaagtacag
     4561 ctgtaaccca atcacaccta aacggctctt aatggtgtat ggattccaat tagctaaatc
     4621 tttgatactc atgatcccca tttggttgag cctttttttc attcgagaac caatacccca
     4681 aaagtctgtc atttcaggaa tattccatac tttatcagga acattttgat acgtccattc
     4741 ggcaataaat ccttcattat gcttcgcttc attgtctaag gctagtttag ccaaaagagg
     4801 attatcgcca acacctactg tagcaatcaa tcctagctct tctttaatac gttcttggat
     4861 catttgagcg agattcttcc ttcgctgact tcgtgttcct tcagtcgtaa aaagattcag
     4921 tgatcgggtc acttttaaga ttgattcatc gatcgagtaa atcagtagat cttcatcagc
     4981 cacatatctt ctgaaaatat tatttacctg catattacgc ttaatataaa ggttcatacg
     5041 tggtggaaca acatgtaatg ttttagggaa aggctgtggt agatcccgtg gtctgctgac
     5101 attagaaata ccatatttct tctttgcagc tggtgaagaa gctaaaatca accctgatcc
     5161 tgtattatcc gctcgactca tgacaactaa ttcagtcgtt aatggatcta aatttctttc
     5221 tatacattcg acacttgcgt aaaaactttt catatcgatt agaaagtagt cattgactgg
     5281 ctcttttgag taatcaagca taaagttctc cccctcttct ctcatattat acaaacatac
     5341 gttcgtgttt gcaacgagga tcttctctaa atagaaaaat agccagacaa ttgtctgact
     5401 ataataaacc tatttgtttt tttcgtttag caattggaag tcttgatcaa tgaattggta
     5461 acaattccca caatttttac aattgtattg tttcgtttga atattgagtt gaatcaactc
     5521 accacaagca cagtcaatcg atacagccgt tcttcgttct aatccgtata atggacgtcc
     5581 ccaaagagtg tagcctaatt gttgttcttt catttacttc gttcctccct aaaaatatgt
     5641 ctattcgtag ctggtatgac gcttcgttcg accaatgata catcttaatg agtgaacctg
     5701 accttagaat gctcgtataa acaacgattt atttgattta aaagagattt ttatattaat
     5761 tttatcaatc ttctactcac tcgcttctat ttgtttctta attctaaaaa gtgtactacg
     5821 actgaaaccc gttatggctt ccacttcttt atacgatttg ccggaagtaa tcaattcata
     5881 tgcatgcctc ttctttggtg tgattgttgc tttcggacgt ccctctttaa aattaggatt
     5941 attctttttc gcaaataatt tcccttcctg agtacgttct acaatcatat cacgttccat
     6001 ttcagctaca ctcaacaacg tacgtgtaac cattcgaccc atcgatgtat tttcgatcgt
     6061 ccctagattc aataccttaa tcgtgacgtt atcatcgagt aaaggttcaa tgatctctag
     6121 tgcttctctt gtattacggg cgaatcgatc aagtttcgta acaacgattt cgtctccagg
     6181 cttcagacca gccaacagct gattaaactt tggccgatct cgtttcgtac ctgtaaattt
     6241 ttcagaaaaa atattcttct tctcaacacc gttctcaagt agctgttgta tctgttcctt
     6301 tgtactttga gaagcggttg agacacgtgc atagccatat tttgtcattt aactcacctg
     6361 cttttacaaa tcatctatcg tatactcaga gtatccttca tagaagtagc tgacatcgat
     6421 tcctttcata tataactcac gatcgtcaat tttatcagtc agggcattgg aaatgagata
     6481 gcgtatttcc aagtcattta ttggactgcg ctccattgca gaaagatagt ctgctttatc
     6541 gatcaagttc caatcgacca ctttttgcaa ttcttccttt aaaatgagat ccagccaaat
     6601 tctagtactg cgcccgtttc cttcgcgaaa agggtgagcg atattcattt ccacgtattt
     6661 cttaataatc tcttcgaaag aagtttgcgg catctgatca atatgattta aagattgttc
     6721 taggtacatg accggcgcaa aacgaaaatt tccttttgca atattaactg tccgaatttt
     6781 tcctgcaaaa tcataaattt ctgaaaagag aaaatcatga atttcagaca agcctttaaa
     6841 cgtgccgact tcgatttcat ttatttttcc agaatcatat aattcttttg ctttttgctt
     6901 actgagtttt tcttcagcct tggccaactc aacctgattc gttaaaccca atttattttc
     6961 taaaatcatg gaaaatcccc ttaacttttt gacataagtt tatgaaacac tacaaatcct
     7021 attgtatcgc gaatttaacc atgtgtcaaa aactattaag tttttgacac gtagttagtt
     7081 ttcaatagaa gccatctgtc cttttctttt taaatggcaa aaatttttta ttttattcgg
     7141 cacaaactat aaacatttaa tcgctaagaa aatcactcaa ttattttgag tgattttttc
     7201 agttcttatt ttaaaacaaa gtgttcataa aatcaggtgt ttctttattt ttcagtagca
     7261 taccctgttt ttattttgag tattagtaat aattaaaaaa accacttgta attttat
//
LOCUS       DACBZK010000097         7111 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.101, whole genome shotgun sequence.
ACCESSION   DACBZK010000097 DACBZK010000000
VERSION     DACBZK010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7111
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.101"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..903
                     /locus_tag="IVD66_002468"
     CDS             <1..903
                     /locus_tag="IVD66_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAP6146645.1"
                     /translation="GFTKQSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSY
                     PLVGPATWDGKVYVQNLFNAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGF
                     KACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESL
                     IGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGW
                     KVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELG
                     MICGKLDRQYYSASAISSIVIPPK"
     gene            916..1824
                     /locus_tag="IVD66_002469"
     CDS             916..1824
                     /locus_tag="IVD66_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HAP6146646.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETRIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            1824..2444
                     /locus_tag="IVD66_002470"
     CDS             1824..2444
                     /locus_tag="IVD66_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146647.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            2448..2897
                     /locus_tag="IVD66_002471"
     CDS             2448..2897
                     /locus_tag="IVD66_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146648.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
     gene            2897..3391
                     /locus_tag="IVD66_002472"
     CDS             2897..3391
                     /locus_tag="IVD66_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146649.1"
                     /translation="MADIVQLKEDGVAKYLKTHVKAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            3405..3752
                     /locus_tag="IVD66_002473"
     CDS             3405..3752
                     /locus_tag="IVD66_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146650.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKSGTAVDDIEDVDQLKQLNALLTKQLAISVQEQEKMQQMLAQLTM
                     EVASIKNGGKSNE"
     gene            3745..3885
                     /locus_tag="IVD66_002474"
     CDS             3745..3885
                     /locus_tag="IVD66_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAP6146651.1"
                     /translation="MNSFPGFENIKQFYDWGCYTDQDLLDYVNMNCLTKDQYKQITGN
                     EI"
     gene            3985..4374
                     /locus_tag="IVD66_002475"
     CDS             3985..4374
                     /locus_tag="IVD66_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HAP6146652.1"
                     /translation="MTGVIGGTIVGLLGGMDNILHVLIFLVGVDFLTGLAKAWKLKEI
                     SSEIGFEGLLKKVLIFVVIAVAVDVQKIVGNSIPLREIVIMFYVANEGISFLENISVF
                     LPLPDKLKEVFQQIRNDTENKDRGGTK"
     gene            4371..5381
                     /locus_tag="IVD66_002476"
     CDS             4371..5381
                     /locus_tag="IVD66_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP6146653.1"
                     /translation="MKKKIFVGAIIALFLLPINAFAYSINNEFNLGANEGSSQVANNQ
                     YILLHETANETATGRNEAQYMKRSWYNAYTAYIVGDGGIVYQVGQPGYVQYGAGSYAN
                     ANSPVQIELQHTHDKVTFEKNYKAYVELARDSANKYGIPLTLDTPYNQPGIKSHLWVT
                     QNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTL
                     SDGTNHSHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPD
                     VNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIP
                     KR"
     gene            5496..6704
                     /locus_tag="IVD66_002477"
     CDS             5496..6704
                     /locus_tag="IVD66_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146654.1"
                     /translation="MTAEIGIMNKSGIVLASDSASTIGDSKVYNTAKKLFTLDSMHSV
                     GIMIYGNAEFNGIPWEIIITQYKKSIGSSVFNTLEEYADNFIEFVKTASFIRSEQTEQ
                     EQMIGVFQKIISGLFESIEVDINFLISQGTQIDKDVLVKLLQTKMNTNLSQQSQTFIL
                     DIEKALFLSNYGEILKDILNSISTMEGVSEAISEEIQSYVYEIIIRDDVYSSPTGIVI
                     AGYGRMDIFPKLYSYNMFGFVMNILKYSEYESAQIGNDNGSLRSTILPFAQSDVVNTV
                     VQGVDPQITNYLSSQVDSFDDNGKNTYINIIKNISEFQQNQFIFPLLNMIALLPVEET
                     AIIAETLLNLTSFKRKYTTSVETVGGPIDVLAITPNDGPIWIKRKHYFDIDNNIGYRL
                     RKERANDYNN"
BASE COUNT         2533 a         1052 c         1477 g         2049 t
ORIGIN      
        1 ggatttacga aacaatctgc atgtggaata ttggggaaca ttcaacaaga aacaggagga
       61 acttttgatc ctgatactgt tcaaataggt ggaccagcat acggattagt tcagtgggat
      121 ggttcttcat atcctcttgt tggtccagca acatgggatg gaaaagttta tgttcaaaac
      181 ttatttaatg ctgcaggtat taaagaacca ataacgagct tagatgcaca agttcgattg
      241 cttatttgga catttacaaa tggacaatgg atgggcgtag tacaacctac gacggttgat
      301 ggatttaagg cctgtactga tccaagacaa gcagcatatg cttttgaacg aaactatgaa
      361 cgtccggcag cgacacatcc tgaacgtcaa gattatgcag ttaactggta taacaaattt
      421 aaagatttaa aaccaggagg agctactgga gaagcaggac taaaacattt agagtctttg
      481 attggacaac gaattggcaa tggtcagtgt tatggcttgt ctgcagaata ttcaggatat
      541 ctgggtggtt gtggcatggg tgctggaaca aaatatggtt taactcatgt gataggaaat
      601 acttctgcag catctgatat tggtattgcc tatgattggt ctgctgttgg ttggaaagtg
      661 attcaaaacc ctagatatga tcaattagta gttggtgcaa ttattaattg ggcaagaggt
      721 ggacaagtgg gttcatggtt tgcagacgga acttatggac atactggcgt tatccgaggc
      781 ttagctaatg gtcgtatgca aacttatgaa caaaacacag agttaggtat gatttgtgga
      841 aagttagatc gccagtatta tagtgcaagt gcaatttctt ccattgtcat accaccaaaa
      901 tagggaggtg atttaatggc aaagtggaat gtcatattaa gtacaacaga accctataat
      961 tacgtgggga tgattcaagt tcgacaaggc aataaaaaca ctgaagttat ggaagctaca
     1021 attgtcgaaa atggtcttcc atatgattta tcagaatgta aggtatattt tgaatcagtt
     1081 gttggcggaa aatatccagt ccaattagaa acaagaattg tggatgctaa aaaagggaaa
     1141 atcaaatata tttttgataa atattccatg cagtgtttgc atcgacaaac agccaatttc
     1201 attatattta aaggagaaga cttgattgga acaactcaag acttctccta ttttgtcatc
     1261 aatgctgttt caaaaacaga aggagaaatg ggttcttatt ggcaatcaat tgaagattta
     1321 attgctgata tgacagattt tattaatgaa aataaaggcg attttacgga ctggatgaat
     1381 gaaaggaaag aagaatttga tcgctggaga gaagaacagg agaatagttt ccaagattgg
     1441 agagaaggac aagaatcaga ttatttgtca tggtttgaat caatcaagga tattttgaag
     1501 tctatcgatc caggtggagt aatgttagcc gaattaatgg atgcacgtgt agatcttcaa
     1561 ggtgtacgcc atgaatcgat ttctgaacgt ttcctatccg atctaaatta tttgtatcaa
     1621 aaaatgaaag cagcactttt cacgattgaa tacggtgaaa ttgaagtgac tgatattctt
     1681 caagacgatc tcttttcaga taatcacgaa gtcgaaaaag ttggaactgt agaattcccg
     1741 attgaagaag gagccttgat catcgcaacc gttgatgatc caaagcaaaa tgtgttcact
     1801 cttgagaaag tcggggtgat ctaatggcta aaactaaacg aatgatggaa acggatgaaa
     1861 aaacaggtgt acaacgccaa ttctttccaa tcacacatgc ttccgcagtt cttgggttag
     1921 aagaaataat agcaggagaa gcaacagttt tatctgttaa tggaaaaatt ggagccgtcg
     1981 tcattactaa agaagatttg ggattagaga atgttctcac agaattaccc tatgcaagtg
     2041 aagaagatga cggcattatc acggcagaaa tgtatcaaaa aattttaaac agtggagaag
     2101 gtgactacgt gttgccagtt gccactatcg accgtttggg tggcataaaa gttggtgaat
     2161 tattgacgat tgatgagaca gggaaagtct ctgcagtcag acaatctgat gtcaattttt
     2221 cgctggagtt aaaagaaaaa ctcgattcac tgaaaaatta tactgctgga gaaaacatca
     2281 ctattgatga agatggaaca attagttcta caggtggtag tgggactggt ggtgtcaatc
     2341 agtcatatgt agatcaaaaa ttccaagaag ctgtaaatca agcagaaaat tacacaaacg
     2401 aaagaattcc aaattttact tttgaaaaaa ttggggaggt atagagaatg acagatatcg
     2461 taaaaataaa acaaagcaat gtacaggttt atccacaaac tcattggaat gctatagaag
     2521 gcaaaccaac aacggtgaag ggagataaag gcgatcctgg ccaagcagca acaattacca
     2581 taggaaccgt ttctagtggt tcaaccgctt ctgttacgaa tgtaggaaca tcatctgcag
     2641 ctagatttaa ttttgtttta ccaaagggag ataaaggtga tcctggaata aatgccacaa
     2701 ctacagctgt agctacaact acagcaaatg ggttgatgtc gtccacagat aaaactaagt
     2761 tggatggaat tgcagctgga gcacagaaaa atccaggtaa tgctacaact acgacagcag
     2821 gtttaatgtc agcaaccgat aaagtgaaac ttgatggatt agccaatatt acatttgaga
     2881 aagtggggac ggtttaatgg ctgatattgt tcaattaaaa gaagacggag ttgctaaata
     2941 cttaaaaacg catgtaaaag ctattgatgg taaagaagca ttggtgcaga cagatggaga
     3001 ccaagccatt gcaggacata agaatttttc aggttctgta acaatcaata ataaacgtgt
     3061 tttgacgact gatgataaca gatatgaagt ggtaaatctg gttgtcacta acggtaatac
     3121 agggacagca aagctttatc gtgaaggaaa aacagtttct atatattttg tggctttaaa
     3181 cggaaaaagt agtggcggga atgattcggt tattttaact gttccagaag gctatcggac
     3241 accaattagt tttgaacaac tggttgggtc aatagaccgt tctactttga acagtgctca
     3301 actatctatt ggcgcagacg gagccattaa atggagaaga aattcaagtt atggatcagc
     3361 ttattcattt gttatcactt attcaattta agggaggaaa tctaatgaaa gtagtttaca
     3421 aatcaatcaa gccttacgga ttcgagcaaa tcattttgaa caatcaagaa aatatccctg
     3481 aaaactgtac agagattaaa ccaccagttc ctaactggag accaagattt gattttgata
     3541 aaaaacagtg ggttgagtta gctactgaag aagagaagag tggcacagcg gttgacgata
     3601 ttgaagatgt cgatcagttg aagcaattaa atgctctact gacaaaacaa ttggcgatat
     3661 cggtacagga acaagaaaaa atgcaacaaa tgttagctca attgacgatg gaagtcgcaa
     3721 gtattaagaa tggagggaaa agtaatgaat agttttccgg gctttgaaaa tataaaacaa
     3781 ttttatgatt ggggatgtta tacggaccaa gatttacttg actatgtaaa catgaactgt
     3841 ttaacaaaag accaatataa gcagattact ggaaatgaaa tttaattaag cacaaagtta
     3901 aataaaaagc gtactcaaac gagtgcgctt ctttgcataa aggagaaata gatattggaa
     3961 aaatatttaa atacactctc agtaatgaca ggggtgatag gcgggacaat tgttggttta
     4021 ttgggaggga tggacaatat actacatgtt ttaatttttc ttgtgggtgt ggacttctta
     4081 actggacttg ctaaggcatg gaaattgaaa gaaataagta gtgagatagg tttcgaagga
     4141 ttgttgaaga aagtcttaat cttcgttgtg attgccgttg cggttgacgt acagaaaatc
     4201 gttgggaatt ctatacctct aagagaaata gttattatgt tctatgttgc aaatgaaggg
     4261 attagttttt tagaaaacat ttcggtattc cttcctttgc cagataagtt aaaagaggta
     4321 ttccaacaaa tacgaaatga tactgaaaat aaagaccgag gaggaaccaa atgaaaaaga
     4381 aaatctttgt aggagctatt atagctcttt ttttattgcc aataaacgcc tttgcttact
     4441 cgatcaacaa tgaattcaat ttgggcgcaa acgaaggtag ttctcaagta gcaaataacc
     4501 aatacatcct attgcatgaa acagcaaacg aaactgcgac aggacgaaat gaagcgcagt
     4561 acatgaaacg ttcttggtac aatgcctata cagcgtatat tgttggcgat ggtgggatcg
     4621 tttaccaagt tggacaacct ggttatgtac aatatggcgc tggttcatat gctaatgcaa
     4681 atagtcctgt gcaaatcgaa ctgcaacata cgcacgataa agtaacgttt gaaaagaact
     4741 acaaggcata tgttgaatta gcgagagatt ccgctaataa atacggtatt ccacttacat
     4801 tagacacacc gtataatcaa ccaggaatca aatcacattt atgggtaact caaaacattt
     4861 ggggcgatca cactgatccg tatggatact tatcagaaat gggtgtaagt aaggaaaaac
     4921 tggcttacga tttagctcat ggatttacag acgaaaaccc aacgacttct gagaacaagc
     4981 ctgtcattga tccaacccga gcaggtgcag caaatccaac tttatcagat ggaacgaacc
     5041 attctcacat tgatcagttt ggagaaatcg aaaatgcgaa cttacacgtc gctggatggc
     5101 acatcgctaa ctataaatac gagtatattt tcattatgga ctacaatact gggaaagaat
     5161 tagctcgagt aagagctgat ggaatttata gaccggatgt aaatcaagct tataatactt
     5221 ctggaaacgt tggctatcat gtatctttta acatgcgcaa tttccctaat aagaaagtat
     5281 acgtcatgat gcgggcaacg aatgatccag aaggaaacac taaaggcggt gcgcaagatt
     5341 tccatgacaa acgttggtat ttaaatattc ctaaacgata aaaatagctc ctcgttgagg
     5401 agcagtacat agaattgaaa attaacgtta aatcaaaaaa atatttacaa gatgtttatt
     5461 taagtagata ataaaagaaa aaagcaggtg aaattgtgac agcagaaatt ggtattatga
     5521 ataaaagtgg aatcgtgtta gcttcagatt cagcatctac gattggagat agcaaagtat
     5581 ataatactgc aaaaaaatta tttactttgg attccatgca ttctgtaggt atcatgatat
     5641 atggtaatgc tgaatttaat ggtattcctt gggaaataat cattactcaa tataagaaaa
     5701 gcattggtag ttctgttttt aatactttgg aagaatacgc ggataatttt atagaatttg
     5761 tcaaaacagc atcttttatt agaagtgaac agaccgagca agaacaaatg attggggttt
     5821 ttcaaaaaat aatttcaggt ttatttgaga gtatagaagt agatattaac tttttaataa
     5881 gccaaggtac acaaatagac aaagatgtcc tagtgaagtt attacaaaca aaaatgaata
     5941 ccaatttgtc tcaacagtcc cagacattca ttttagatat tgaaaaggcg ttatttctta
     6001 gtaactatgg agaaatatta aaagatattc ttaatagtat ttctacaatg gaaggtgttt
     6061 cagaagctat atcagaggaa attcaaagtt acgtttatga aattataatt agagacgatg
     6121 tttattcttc ccctacagga atagttatag caggatatgg aagaatggat attttcccta
     6181 aactatattc ttataatatg tttggatttg ttatgaatat tctgaaatac tcagaatatg
     6241 aaagtgctca aataggaaat gacaatggtt cattaagatc tactatatta ccatttgctc
     6301 agtctgatgt ggtaaatact gtagttcaag gggtagatcc acaaattact aattatctgt
     6361 cgagtcaagt cgatagtttt gacgataacg gaaaaaatac ctatattaat attataaaga
     6421 atatttcaga gtttcaacaa aatcaattca tatttccgtt actaaacatg attgctttac
     6481 tcccagttga agaaacagca attatcgcag agactttatt aaatttaacc agttttaaac
     6541 gaaaatatac tacttctgta gaaacagtag gtggcccaat tgatgtttta gctattacac
     6601 ctaatgatgg ccctatttgg attaaaagaa aacattattt tgatattgat aataatattg
     6661 gatacagatt gcgaaaggag agagcgaatg attacaataa ttaaacctca ggaaaaatcc
     6721 cctgttttga aatttaatga gagcaatcta gcccataata aaatgagtat aactgataca
     6781 gtatttgatg taatggttga gcaacaaaaa aaaattaata ataacaatag acaaagaaaa
     6841 gaaattaacc aatattaatg ttttttctgt tgcgtttttt gcagtcataa tttaaaacct
     6901 cgctcaatct tgggcgaggt ctttttttat ttttctgaaa agttaaagta aataatagca
     6961 taaaataata tattttacaa agaataagta caatctagtt ttttgctatt aaatgtgtaa
     7021 taataaatat gccatcacaa catgaagaat gaaatccatt attatctagt ctagtccatt
     7081 ctttttgttt gcagtatttg tgatggcttt c
//
LOCUS       DACBZK010000098         7089 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.102, whole genome shotgun sequence.
ACCESSION   DACBZK010000098 DACBZK010000000
VERSION     DACBZK010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7089
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.102"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            45..587
                     /locus_tag="IVD66_002478"
     CDS             45..587
                     /locus_tag="IVD66_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAP6146655.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(670..1221)
                     /gene="lepB"
                     /locus_tag="IVD66_002479"
     CDS             complement(670..1221)
                     /gene="lepB"
                     /locus_tag="IVD66_002479"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP6146656.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(1373..1600)
                     /locus_tag="IVD66_002480"
     CDS             complement(1373..1600)
                     /locus_tag="IVD66_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAP6146657.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(1597..2115)
                     /gene="msrA"
                     /locus_tag="IVD66_002481"
     CDS             complement(1597..2115)
                     /gene="msrA"
                     /locus_tag="IVD66_002481"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP6146658.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(2135..2848)
                     /locus_tag="IVD66_002482"
     CDS             complement(2135..2848)
                     /locus_tag="IVD66_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAP6146659.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(2851..3747)
                     /locus_tag="IVD66_002483"
     CDS             complement(2851..3747)
                     /locus_tag="IVD66_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP6146660.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(3905..4747)
                     /locus_tag="IVD66_002484"
     CDS             complement(3905..4747)
                     /locus_tag="IVD66_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP6146661.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            4879..5532
                     /locus_tag="IVD66_002485"
     CDS             4879..5532
                     /locus_tag="IVD66_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAP6146662.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(5595..6122)
                     /locus_tag="IVD66_002486"
     CDS             complement(5595..6122)
                     /locus_tag="IVD66_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP6146663.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6142..7089)
                     /locus_tag="IVD66_002487"
     CDS             complement(6142..7089)
                     /locus_tag="IVD66_002487"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAP6146664.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
BASE COUNT         1906 a         1389 c         1252 g         2542 t
ORIGIN      
        1 tttatggtat ccttttatta ttaactgaca aaggagagaa tattttgaac actttgattg
       61 caaaagacgt ttttagattg cccgaaatga atgcaagatt gttgtcgacc tctgctcttt
      121 tattagccct tgatgtcatc ttatacaaga tagcgattgg tcctgcttat tttcaaatca
      181 cattcggatt tttaagtatg gcgcttatgg gttatctata tggaccgatc tgggctggtt
      241 tgcttgaaat gttgtcgaac actttaaatt tcacgatatt tggttcagga acgtttcaag
      301 ctgcttttct tatcacggct ttccttggtg gatttattaa tggcttattt ttatatcata
      361 aaaagataaa cctgccttcc gtcatcgctg cccaattatt gattatgatc ccagtcagcc
      421 tttttatcaa ttcttggctg atgtctgttt tgtttggtgc agatttcaaa gtaatttttc
      481 taggtagatt catcaggaat atgatccaaa tccctattca aataatggtt gtttattcat
      541 ttatcaaaac tttagaggct agaaaagtgt ttaaacgagc tgtttgattt tacgtactaa
      601 ggtagtaaac tgattttgga ttaaacaata aagcgtgcag tctcaacaga ctgcacgctt
      661 tattgtttct cactggatcc attttatttc atcaagtgga taatagacaa atcttgcttt
      721 acctagaata tcagttttat tgatcgtgcc aaacgaacga ctatcttttg aaactcttcg
      781 attatctcca agtacaaaat aattatcttc cggaagcttg gattgtcccg ttagctcttg
      841 tagtgtaaag tccgtcgtat aggatgcatt tgcatgatct gatttcaggt ttttagttag
      901 ataaggttcc ttaactactt tcccattgat cttcaattga tcattttggt agctgacatt
      961 ttctcctgga agaccgatta ctcgtttgat ataaatcgtg ccatctgcta attgaaaaac
     1021 aacaatatca aatcgtctga tctccgaaaa tttttccatc acaaccatat caccttgctt
     1081 caacacgttt tccattgaat tgccttccac tggtaccggg atgaataaaa atccccgcaa
     1141 catgaacgca aggaatacag aaacaagtaa gtatttgaat acaagccaga agcgattaat
     1201 atagcgttgt ttttttgtca atctctatca atccatccct ctttttttca ttctttcttt
     1261 attataagaa aaatatcaaa aaaatgcgac tagatagctg aaataaaaat aattctttca
     1321 attaggctat tggacaaaaa acttttttga tcataaagta caaaactatc tcttatatgt
     1381 catgattatt ttctaaatat ttttcccatg cttcgtcaaa gatatccatg gacggcaaat
     1441 agtcgacatt cagttccaga taattagaaa tttcttcgta gctagagctg tgcttaggaa
     1501 attggatgtc tttaccggct tctgtagcga aaacagataa agcatcatgt gtgccaccgc
     1561 ctcgcagtgt cattaaataa tgaaaaaagc ttcgattcac ccttcgttcc tccaattttc
     1621 ttcgataaag gcagcccggc gtgcatggtt tcttttaaaa ttttcaggat gctttttata
     1681 atactcttga tggtcttctt ctgctagata aaatggttgg gctggttcga tttttgtaac
     1741 gattggctgt tcgaaacgtc cactttcagc taactgtttc ttactttttt cagcaatgat
     1801 ccgctgttct tctgtcaaat aaaagatcac cgggcgataa ttgtcaccgc gatcctcgaa
     1861 ttgtccgaaa gcgtcagttg gatcagtttg ctgccagtaa agttctacta attgttcata
     1921 tgaaatcaat gttggatcat agataatctc cactgcttct gtatgtccag tcgtttggct
     1981 ttttacttgt tcataagtcg gatctggtac atgccctcca gtatatcctg acatcactgt
     2041 atggatacca ggaagcgtgt cgaaaggctg gatcatacac cagaagcagc ctcctgcaaa
     2101 tattgctcgt tccattatga ttccccctct aatactactc atccgatgat tttttatttt
     2161 cttttgtctt gctttcagta ctgctggtgc tagttttgtt ggtatttgag ttgtttgaag
     2221 catcagaggt atcttttggc aaatatagac taaaccgaat gtcatcattt actaagtcga
     2281 ttttatctgc tttaatatac atcccgtttt gcattcggaa ttgatccaac ctaagcatga
     2341 tagtcagatc atctgtattg acttcgatcc aatctggtaa tttatagttt ctcttgatca
     2401 tattcatcac atctttgatt ggcaaactca atgttccgat agaaagactt ctagctttta
     2461 gttggacatt tccgttttcc atcacatacg gatcaaaata taaatagaaa tcgataggaa
     2521 aacctagtac ttcgaaagta ccattgagta gtgcttcatt ttccaaataa aatttatatt
     2581 caatatcact atctttttga tactcactaa ggaaaaagct gatgatttga ttgacttttt
     2641 ctttatttga attgatcgtt aagacaggat ctccttgtct ttccgtaaga gctggtattt
     2701 ctgggagttc tggttcccga ttagcaaaaa tacggctgcc taaaaatacg gtcgaaccaa
     2761 gtactacccc aagaaggata aggaaggcga atttccagta atttgttttc tttgttttgt
     2821 ttgaagatac gtcagatctt gttttcatgt ttattgatca tcctccttct ctaaccattg
     2881 gttttgtgtc tcgatcagct gatctctcac tgcatttgcc atcaattgat aacctaaatt
     2941 atttggatgg aaatgatctt cttcatagag cacattattt ttgatgccat ttagattttc
     3001 tgtcgtgcta gttgtttgat ctgttccttc ttctgtgaca cctacttcct gattcaatcc
     3061 ttgataaagc aaatcattga ttgggataaa gtagcagttc ggcatttttt ttgtcaccgt
     3121 ttctgttcct ttgttccaat tgttaacaat tgtctgcatg tcagtgatct caggaaagtt
     3181 caaataaaat ggattgtaga tgcctaaaat gtaaataggt gcggttttat tgagggatcg
     3241 aaattcttcc aatagttctg tgacattttc ctgatagttt ttcagtggct ttttaaagga
     3301 attgaccgtt aacccgaata aattattttg gataactttc atcaaatcat taccgccaac
     3361 agtcagtgtg ataaaatcag ctgttttgat attgtttcga atttcttctt ttgtttttac
     3421 tcgctttaag atctggtcac ttcgttcacc atttacacca tagttttctg tttcaaccgc
     3481 ggtcaaatta taacggtctt ttagatcatt tgcgacaagg ggaacgaatc ctccttgctt
     3541 ggtttgatct cctactcctt cagtcagcga atctccgata gctatgtagt gaagtttttc
     3601 ttttttattt ggatcttctc tcacagtagt tactggtttc attagtgggc cagctttcgg
     3661 tatagaagca gctaaacctg catagatgat gatcgcaatt aataatggga acaaaacgag
     3721 gatcaaatgt cgtttcgtta atttcatttt ttcacctctt gtattcgatt ggttctaatg
     3781 ttatcaaaaa ttttatcaaa aaggtagtct ttatgaaaaa agaaaacaat tattttccta
     3841 attttataaa gaaaaagaga ataagctgca agcctttcag gctgagggct tatcctcttt
     3901 tcgactaatc tacataatac atgattgcaa acgcgtcttt accagtatgc gtagcgataa
     3961 ccggattcgt atgcagtaca gggatatgca tgtccgggaa taattcttgc aaaccctctt
     4021 tgaattcttg cgccaattct tttgcatccg catgtgaaat accgatttgt cgcacatttg
     4081 gcaattcttt cagttcattt ttcaaattat taaaccattt atcgaacgtt ttctttcctc
     4141 gccccttagt tacagggatt aattcagaat gggcgaaatt catcaccacg cgtatgttca
     4201 aaacactaga cagcaaacca gttgttcggc tgattcttcc accttttacc aagttatcta
     4261 gtgtggatat tccgatgtat aattttgtat tgtcttgtac ttttttgact tcttcaagga
     4321 ttttctctac tgttttacct tcttttgcta attcagctgc tcgaattacc tgaaaagata
     4381 atccttggtc agtggtatca ctgtcgataa ccgttacttt cgtttttgtt agattactgg
     4441 cttgtcttgc tgcttctact gttccactca agccttttgt catatggatc gaaatcactt
     4501 cactgccgtc ttctcctagc tcatcataca tcgagatgaa ttctccaatt ggtggttggc
     4561 ttgttttggg cagatttttt gctttcgcca tcatttccat aaatctttcg ccgtctagtt
     4621 ggtcatcatc gggatatact gttccgtcga tcatgatgga tagcggcatg acacgaatgc
     4681 ctaaagcatc gcgtacattt ttttccatcg tacatgaaga atctgttacg atttttacat
     4741 ttgtcattat tttctctctc tctttcttta acaagatgcc ttattcatgt taaactacat
     4801 gtaagacaat ttctattttt agtataacag acaaataatg atttttcatt aattacacct
     4861 agtaaaggag ccgttttcat ggaaaaaacg aaatttaatc gaacgtatga aatattaaat
     4921 gaagtgttta atgcagtcac ccatggaatt gggactggat tgagtatcgc gggactagtg
     4981 gttcttttag taaaaggtgc ccacttgcat tcctccctcc atattgtctc ttatgctatc
     5041 tatggatcga tgatgattct tttattttta acgtctactt tgtttcattc attgattttt
     5101 acaaaagcaa aaaaggtgtt ccaagtattc gatcatagtt cgatttttct tttgattgca
     5161 ggaagttata ctcctttttg tttgctgagt atccgaggat ggctaggttg gactttattt
     5221 gtattaatct ggttgtttgc gattcttggc attatatata aagcgttgac gttgcataaa
     5281 cgggagagag tatcaaaagt atctacgatc atctatattt ttatggggtg gctctgtgtc
     5341 gtggctgctg ttcctcttta tcactctctt ggaatgactg gtgttatttt gatggtagca
     5401 ggcgggcttt cttacacgat aggcgcattc ttttatagct tgaattctat ccgctatatg
     5461 catgttgttt ggcatttgtt tgttatgtta ggtgcaggtt ttatgtactt ctctgtttta
     5521 ttctttactt aataaaaaaa ataaagctat ggatgggaca gctctaaata acagctagtc
     5581 tatccatagc ttttttatat cgtcaattcg cctgtcccgc tttttacagg attctcatta
     5641 cgctgatacg tttcaaattg atgcggataa cgattttttt catccatttc tccttgacta
     5701 gtattgatca gtgaccaatc agaccagtca acaggtggaa aataagcatc tccatcgaat
     5761 acatgatgga tgactgtacg gtataatatc gtacaaaatg gcagaaattc ttgataaaca
     5821 gctgaccctc cagcgatgaa aaagataccg tctgtttctt tttccagagc aagcacgtct
     5881 tccacactat gcatgacatg cacgccttct gctttatagg aagaatctct cgtcaaaaca
     5941 atcgtctgac gattcggcaa cggacggcta cccatccctt cgaatgtttt tcgtcccatc
     6001 actagtgtat ttgcttctgt catttgtttg aagaatttca gatcatttgg caaacgccaa
     6061 ggaagacggt cttcttttcc aatcaatccg ttttcatcct gtgcccaaat tgcagctaac
     6121 attttctcat cctttctgat tctaaacagc gataggagct ttgatcgccg gatgtgggtc
     6181 atatccttct aattggatat cttccatctc aaaatcaaat actgactgct tttcctgatt
     6241 caaaactaaa gtcggaaatg cgcgtatttc tcggctcaat tgttctttca tttgttcgat
     6301 atgattgata taaagatgag catctcctaa tgtgtgaaca aattcgccaa ccgctaaacc
     6361 tgtttcatgt gcaattaggt gagtcagcaa cgcataactt gcaatgttga acggaacgcc
     6421 tagaaacaca tccccactgc gttgatacaa ttggcagctt agccgtccct cttgaacata
     6481 aaattgaaac atcgtatgac aaggaggcaa agccatgcta ggaacatctt ccggattcca
     6541 tgcagaaacg atcaatcttc tagaatcagg agtctttttg attgcttcga tcacttgttt
     6601 gatttgatcg ataaagccac cgtcttttgt ttcccagtga cgccattgat agccgtagat
     6661 gtgtccaaga tcgccgtatg tttcagcaaa ggaatcatcg gttaggatct tctcgcaaaa
     6721 aagcttgctc tgctttttat attcttcatt gaattcagga tctgtcaaac atctatggcc
     6781 aaaatcagtc atatctggtc cattatagtc tggacttttg atgtagcgtt caaatgccca
     6841 ttcatcccaa atatggtttt tattttgtaa tagatagcgg atattcgtat ctccttttaa
     6901 aaaccaaagc aattcgcttt tgatcaatcc aaaaggtact cgtttcgttg ttaacaaagg
     6961 aaaccctttt tgcagatcaa accgcatttg gtatccgaat aagcttaatg tgcctgtgcc
     7021 tgttctgtct tctttacgat gcccttcttc caacaatttt cttcctaagt caagatacgc
     7081 ttgttccat
//
LOCUS       DACBZK010000099         7022 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.103, whole genome shotgun sequence.
ACCESSION   DACBZK010000099 DACBZK010000000
VERSION     DACBZK010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.103"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            160..1101
                     /locus_tag="IVD66_002488"
     CDS             160..1101
                     /locus_tag="IVD66_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HAP6146665.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1170..1901
                     /locus_tag="IVD66_002489"
     CDS             1170..1901
                     /locus_tag="IVD66_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HAP6146666.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2045..4225
                     /locus_tag="IVD66_002490"
     CDS             2045..4225
                     /locus_tag="IVD66_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HAP6146667.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4245..4727
                     /locus_tag="IVD66_002491"
     CDS             4245..4727
                     /locus_tag="IVD66_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HAP6146668.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            4743..5504
                     /locus_tag="IVD66_002492"
     CDS             4743..5504
                     /locus_tag="IVD66_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAP6146669.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            5635..6969
                     /locus_tag="IVD66_002493"
     CDS             5635..6969
                     /locus_tag="IVD66_002493"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HAP6146670.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
BASE COUNT         2365 a         1229 c         1550 g         1878 t
ORIGIN      
        1 ttctgtgcga aacaggaaag cgaagtcttt ttaattcaaa taataatatt atgtaaacaa
       61 aaaactttcc atgcgtaatt atacacaagc aaataaatcg tcaaatgcga acgccttctt
      121 tatactgttt aggaacgaaa agaaggaagg aagaaataca tggattatca agtactgctt
      181 tattacaatt atacaaaaat cgaagaacca gaggaatttg ccaaaaatca tttagccttt
      241 tgcaaatctt tggatcttaa aggtcgtatt ctagtagctg aagaaggaat aaatggtact
      301 gtgtctggaa ccgttgaaaa cacgactgcc tatatgaaag caatgaaagc tgatcctcga
      361 tttgctgata cgatgttcaa gatcgatcca agcgaaggac atgcctttaa gaagatgttt
      421 gtaagatacc gtccagagct tgtaagttta aagctagaag aggacattga tccaaaccaa
      481 gtgacaggtg cctatctttc accgcaagaa tttaaagaag ctattttaga tgaacagaca
      541 gtggtgattg atgcacggaa tgattatgaa tatgacttgg gacattttcg aggggctgta
      601 cgcccagata tacgcagttt tcgagagctt ccagactgga tccgcgagca caaagaagaa
      661 tttatggaaa aacgggtagt gacctactgt actggtggca ttcgttgcga gaagttttct
      721 ggttggcttg tccgtgaagg attcaaagat gtcggacagc tgcatggcgg tattgctact
      781 tatggtaagg atcctgaagt ccaaggagaa ttatgggacg gcaagatgta tgtgtttgat
      841 gaacggatcg ctgtcgatat caaccaagta gataaacaaa tcgtcggtcg cgactggttt
      901 gacggaacac catgtgaacg atatatcaat tgtagcaatc ctgagtgcaa tcgtcagatt
      961 cttgcttcca ttgaaaatga agaaaaacat ttaggagcat gtagcataga gtgtgcgaaa
     1021 catccgcgca atcgctatgt tcaagaccat ggaatctctc cagaagaagc agaactgcgg
     1081 tttacagctt taattaaata gaaaacaata gttttgattg tcgaccattt ccaatatgcg
     1141 ctatactagc gttgaggatg gtgatccaca tgaaatcatt gatttatgct attggggatg
     1201 tccatggcaa acatgagctt tttgaaaaac ttattcacta ttatgatcca aagatccatc
     1261 agcttgtttt attaggggat ctcaatgatc gaggtcctcg tacaaaagaa tgttttttat
     1321 taggaaagca attagtcgaa gaaacaggag ccatttacct ccggggaaac catgaagaat
     1381 attttttgca atttctgcaa tcaccggagg actggtatgc gccttatatg agaaatggtg
     1441 gaaaagaaac gtttgaaagc ctgattcacc caggggcatc ggaggaatac tccccaactg
     1501 aaatctcgat gatgatccaa tcgagatatt cagaactgat taaattttta gtccagcgcc
     1561 ccttgtatta tgaatgggaa aattatcttt ttgtccatgc cggtgtggat ttgacaaaga
     1621 aagactggcg taagacaagt ctaagagact ttatttggat aagggaacca tttcatgaag
     1681 ggaaaaacaa tacaggtaag acaattgtat ttggacatac gattacacca atgctccatg
     1741 gagatatgca gacaacagac ctctggattc aggatcataa aatcggaatg gacggtgggg
     1801 ctgtattcgg agggtcattg catggggttg tttttgacaa ggaaggtatt cttcaagata
     1861 ttgaatatca gaacaacgaa ggaccttggc atggaatctg actaatggaa agaatgaagg
     1921 agctgtgact ttgttgcggc tctttttatt tttatagaga atattgtttc tttcagtagt
     1981 ttaacccagg ataaaaagta tgatagaata aagaagcaat ttttagcaga aaagaggcat
     2041 tttaatgacg gaaaatttga accagacgat cattcagctt gtacaaaaag aactttcaga
     2101 ctatcgtcct aagcagttga ctactgtact taatttgtta aatgaaggaa acactgttcc
     2161 ttttatcgcg cgttaccgaa aagaaatgac tggaagtctt gatgaagtcc agattcgtga
     2221 aatcgaagag cggtatgcct atcttgaaaa cttagaaaaa cgtaaaactg aagtgattcg
     2281 gctaatcgat gaacaaggga aactgactcc cgagttagaa gcagaaatca cccaagccgt
     2341 gaaaatgcaa caagtggaag atttgtatcg tccatacaaa caaaaacgac ggacaaaagc
     2401 aacgattgct aaagaaaaag gacttgaacc actcgcgaag tggctgatgc agcttacaga
     2461 tggagaggtg caatctgaag cagaaaaata tattgacaaa gaaaaagaag tctcttctgc
     2521 cgaagaagcg ttgcacggtg ctcatgagat tattgctgaa caagtcagcg ataatgcaaa
     2581 atttcggact tggattcggt cttatacgta taacaaaggt atgtatgtca gcaatgtcaa
     2641 ggatgagcaa gcagatgaaa aaggcgtata tgaaatgtat tatgactttg cagaacccgt
     2701 ccataaaatg gtttctcatc gaatattagc tactaatcgt ggagaaaaag aagatattct
     2761 gaaagtattc tttcaagtag atgaagcagc aattttagct tacttggatc gccaaatagt
     2821 caaaaatcct gcctctcctt cttcttcatt cgtcagagaa gcctatcagg atagttataa
     2881 acgctttatt cagccagcaa tcgagcgaga actgcgcaat gaattgactg aaaaggcaga
     2941 tgagcaagca atcgctattt tcggcgaaaa cctccgtaat cttttgttgc aaccgccact
     3001 aaaaggtaaa gttgtcctgg gatttgatcc ggcttatcgt actggatgta aactagcagt
     3061 cgtagatgcg acagggaaag ttttagcaat cgaagttatt tatcctcata aacctgcagc
     3121 gcaagcaaaa agagaagctg ctggaccagc ttttatccaa ttaattaata aatatcaagt
     3181 agatatggta gctatcggaa atggtacagc cagtcgggaa tctgaacttt ttgtggctga
     3241 gcagttgaaa tccgccgacc ataaaaccta ttacgctatc gtcaacgaag caggcgcttc
     3301 tgtttactcc gctagcgaaa ttgcacgaaa agaatttccg catctacaag ttgaagaaag
     3361 aagtgctgtt tctattgccc gtcgcctgca agatccttta gctgaattag tcaaaatcga
     3421 tcctaaagct gtcggagtag gccagtacca acatgacgtt tctcaaaaac gtttggctga
     3481 acaattggat tttgttgtgg aaacagcggt taaccaagta ggtgtggatg tgaatacagc
     3541 aagcccgcag ctcttgcagc atatatcagg attgaataaa acaactgccc aaaacattgt
     3601 catttatcgt gaagaaaacg gagaattcac cgcacgaact caattgaaaa aagtgccacg
     3661 cttaggacca aaagcatatg aacaagcaat cggattcttg cgagtccctg gtgggaaaaa
     3721 cattttggac aacacaggta tccatcccga aagttattct attgcaaaag aaatattaac
     3781 ttcagtccaa ctttcagaaa aagagcttgg tacagaagaa gcagtagaaa aattgacacg
     3841 attatccgta gagaaactgg ctgaaagcct atcagtcgga gaagaaacgt tagccgatat
     3901 tttagctggg ctgacacaac ctggacgaga tatgcgtgat gagatgccag cgcccttatt
     3961 acgtacagat gtattgagta tggaagactt gaaaccaggg atggaattga ctggaacggt
     4021 ccgtaatgtc attgacttcg gcgcatttgt tgatatcggt gtgaagcaag acggacttgt
     4081 ccatatatcg aaactcagca aaaaattcgt caagcatcct acagatgtcg tgtcagtagg
     4141 agatatcgta acagtttgga tagaacaagt cgatacgaaa aaaggcagaa tcagtttgac
     4201 gatgctttcc ccttatgaag agtaacaatg aggagtaaca aaaattgaca caagaagaac
     4261 tgcagcagtt agtagaagag atatcattaa aaagcttcca gcttcctttc aagcaccaag
     4321 caatgttcaa tccacgctta cgtacaactg gcgggcgcta tcatttaaac gatcatcatt
     4381 tagattttaa tgcgaagcta tttgaagagt cagacgaaga gacgattgca ggaatcatca
     4441 aacatgaact ttgccattat catcttcatc tagctggaag agggtatcag cataaagata
     4501 tggatttcaa gtatcttttg aaaaaaacag gagggttgcg ctatgcacca gccttgacga
     4561 agaaacagat aaagatggag tattatcgat gccaagattg ttctgccacg atctgccgca
     4621 agagaagaat cgatgtacgc aaatatcgtt gtggaagatg tcatggagaa atcaaatgga
     4681 ttgagacaaa aagagaagac tttaatgaag cacaaaaaat cagatgaaag gatagaaggc
     4741 ctttggaaaa aagtgagcag aggaatctaa aagactggaa tcagctatta aattttttag
     4801 ccgcacctga agagggaaat tttgaggaac tgacggcacc tacacttatt ttagctggaa
     4861 actgtcttcc tatcttagct gataaagcag cacaaatgta tttaaatggc caagtagatc
     4921 aattgttttt ggtcggaggg gtggggcatg cgactagaat cctttatgag aattttgaaa
     4981 agcaaggatt tcattttgaa gatggcatga gtgaaagtga aatctgtcgt cagtatctaa
     5041 aagaagtcta tgatttgccc gataaggctt ttctgataga atcgaagtct acaaattctg
     5101 gagagaacgc cactttttca ctggagattc ttcattcctt aggagctgta ccagaaaaaa
     5161 tcttattgat gaatgatccg acactgcaac gcaggactcg agcaactttt gagaaagtat
     5221 ggcaaaatga acaaactatt ttcgcgaatg ctgtgccatt tgtgccggaa atccttcact
     5281 tttctgaaga gatcatcttt acagcaaaag aactgaatca tcaatggcct aaggaatatt
     5341 tccatgcgct agtattagga gaaatggaac gtctccatga cgatgagaac ggctatggtc
     5401 cgaaaggaaa agattttatt cctcacattg atatatcaga ggaagtttgg tcttcttaca
     5461 ccagaattaa agagtcaata aaaacggatt tttctcgtac ttgaccattt tagcaagcga
     5521 atcctccttt ccaaataaat ttggttgaaa ttttcaatcg tttataagat aatgaggagc
     5581 gtgttgaatg taatagctaa aagaatggac gctagataag agaagaggat tcaaatggaa
     5641 aatcaaaata aattgtatca ttttgttggt atcaaaggtt caggaatgag ctccttggct
     5701 cttgttttac atgaacaagg tctaaatgtc caaggatcag acattgaaaa atatttcttt
     5761 acacaaagag atttagaaaa agcaaatatc acgattctgc catttaacgc agataatgta
     5821 aaaccaggga tgacgatcat tgcaggaaat gcatttcctg attcacatga agaaatccag
     5881 cgagcaaaag aattaggttt ggaagtgatt cgctatcacg actttattgg tcattttatc
     5941 caaaattata cgagtatcgc tgtaacaggc tctcacggaa aaacaagtac gactggactg
     6001 ctctctcatg tattgagtgg tgtccgtcca acaagttatc taattggaga tggaacagga
     6061 catggtgatc cgcaagcgga attcttttca tttgaggcct gtgaatatcg ccgtcatttc
     6121 cttgcctatt caccagacta tgcaatcatg accaatatcg attttgatca tccggattat
     6181 tatacaagta tcgacgatgt atttacagct ttccaaacaa tggctggaca agtgaaaaaa
     6241 gctatttttg cgtatggtga cgatgcttat ttacgcaaat taaaagcaaa tgtgccgatt
     6301 tattattatg gtgtcacaga aaacgatgat atccaagcac gaaacatcga acgcacaact
     6361 tctggttctg cttttgatgt ctatcatggg gatgaatttg ttgggcactt cactgtacca
     6421 gcattcggta aacacaatat cttaaatgct ttaggtgtta ttgcagtagc ttatttcgaa
     6481 aaactggatc tgaaagaagt tgcagaagaa atgctgactt tcccaggagt aaaacgtcga
     6541 ttcagtgaaa agatcgtagc agacatgacc gtagtcgatg attatgcgca tcaccctgca
     6601 gagatcaaag caacgattga tggcgcacgc caaaaatatc cagataaaga aataattgca
     6661 gttttccaac cccatacgtt tacgcgtacg attgcattga tggatgaatt tgcagaagca
     6721 cttgatttag ctgataaagt ttacttatgc gatatttttg gttcggctcg ggaagaacaa
     6781 ggaaacgtta agattgaaga ccttggagcg aaaatcaaaa aaggtggaga agtcatcaaa
     6841 gaaaataatg tatctccatt gttagattat catgatgcag tagtaatctt catgggtgct
     6901 ggagatgttc aaaaatttga acaagcgtat gaaaaacttt taagcagcac gacgaaaaat
     6961 gtactgtaat acaattactg cagtgtcctt ataaaaatag aaagaggggg agtggcaaaa
     7021 at
//
LOCUS       DACBZK010000100         6674 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.105, whole genome shotgun sequence.
ACCESSION   DACBZK010000100 DACBZK010000000
VERSION     DACBZK010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6674
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.105"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            69..152
                     /locus_tag="IVD66_002494"
     CDS             69..152
                     /locus_tag="IVD66_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HAP6146671.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            277..1014
                     /gene="erm(B)"
                     /locus_tag="IVD66_002495"
     CDS             277..1014
                     /gene="erm(B)"
                     /locus_tag="IVD66_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAP6146672.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1184..1444
                     /locus_tag="IVD66_002496"
                     /pseudo
     CDS             1184..1444
                     /locus_tag="IVD66_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase"
     gene            1607..2272
                     /locus_tag="IVD66_002497"
                     /pseudo
     CDS             1607..2272
                     /locus_tag="IVD66_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284571.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2308..2553
                     /locus_tag="IVD66_002498"
     CDS             2308..2553
                     /locus_tag="IVD66_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP6146673.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2656..3525
                     /locus_tag="IVD66_002499"
     CDS             2656..3525
                     /locus_tag="IVD66_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAP6146674.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3506..4240
                     /locus_tag="IVD66_002500"
     CDS             3506..4240
                     /locus_tag="IVD66_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP6146675.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4273..5188
                     /gene="ant(6)"
                     /locus_tag="IVD66_002501"
                     /pseudo
     CDS             4273..5188
                     /gene="ant(6)"
                     /locus_tag="IVD66_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
     gene            5185..5727
                     /gene="sat4"
                     /locus_tag="IVD66_002502"
     CDS             5185..5727
                     /gene="sat4"
                     /locus_tag="IVD66_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HAP6146676.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5820..6614
                     /locus_tag="IVD66_002503"
                     /note="aph(3')-IIIa"
     CDS             5820..6614
                     /locus_tag="IVD66_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAP6146677.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT         2340 a         1005 c         1393 g         1936 t
ORIGIN      
        1 ttgtgtataa taggaattga agttaaatta gatgctaaaa atttgtaatt aagaaggagg
       61 gattcgtcat gttggtattc caaatgcgta atgtagataa aacatctact gttttgaaac
      121 agactaaaaa cagtgattac gcagataaat aaatacgtta gattaattcc taccagtgac
      181 taatcttatg actttttaaa cagataacta aaattacaaa caaatcgttt aacttctgta
      241 tttatttaca gatgtaataa cttcaggagt gattacatga acaaaaatat aaaatattct
      301 caaaactttt taacgagtga aaaagtactc aaccaaataa taaaacaatt gaatttaaaa
      361 gaaaccgata ccgtttacga aattggaaca ggtaaagggc atttaacgac gaaactggct
      421 aaaataagta aacaggtaac gtctattgaa ttagacagtc atctattcaa cttatcgtca
      481 gaaaaattaa aactgaacat tcgtgtcact ttaattcacc aagatattct acagtttcaa
      541 ttccctaaca aacagaggta taaaattgtt gggagtattc cttaccattt aagcacacaa
      601 attattaaaa aagtggtttt tgaaagccat gcgtctgaca tctatctgat tgttgaagaa
      661 ggattctaca agcgtacctt ggatattcac cgaacactag ggttgctctt gcacactcaa
      721 gtctcgattc agcaattgct taagctgcca gcggaatgct ttcatcctaa accaaaagta
      781 aacagtgtct taataaaact tacccgccat accacagatg ttccagataa atattggaag
      841 ctatatacgt actttgtttc aaaatgggtc aatcgagaat atcgtcaact gtttactaaa
      901 aatcagtttc atcaagcaat gaaacacgcc aaagtaaaca atttaagtac cgttacttat
      961 gagcaagtat tgtctatttt taatagttat ctattattta acgggaggaa ataattctat
     1021 gagtcgcttt tttaaatttg gaaagttaca cgttactaaa gggaatggag ataaattatt
     1081 agatatacta ctgacagctt ccaagaagct aaagaggtcc ctagcgccta cggggaattt
     1141 gtatcgataa ggggtacaaa ttcccactaa gcgctcggga ccccttgtag gaaaatgtcc
     1201 taagtgtggc aacaatattg tattaaaaaa atcgttttat ggttgttcaa attatcctga
     1261 atgtaagttt actttagctg aacattttag aaagaaaaaa ctaaccaaaa cgaatgtaaa
     1321 agaattactg gagggaaaag aaaccctggt aaaaggaatc aaaaacaaag agaaaaagcc
     1381 ctacaatgcc gttgtaaaaa ttggggaaaa gggatatatt gattttatct ctttttcaaa
     1441 ataaacatgg ggctgaccca aaagtagctc ctatatgaaa aatagaggtc tttccattta
     1501 gatagtagtg gaaagacctc tatttatctt ttgaaagtga atacaaaaat aaagcacact
     1561 ctgctataat ataggtgatt aatccatttg agagaggtgc tttatcatgt atcaaaatta
     1621 taccataaac caactttgtt tgcctataga tcttgaaatt aaattagaag aaaatgattt
     1681 tgctcatgcc attgtgcagt ttgttgactc tattcccgat gaagtctttc ttccttatta
     1741 tcaatctatg ggtagacccc aatatcatcc tcgtatgcta ctttccatta ttctttgtgc
     1801 ctatattcaa ggggtttatt cgggccgcca aatacaaaat atgctgatag atagtattcg
     1861 gatgcgctac ttatctcaag agcaattccc taactttcgt actattaatc gttttcgcgt
     1921 tcatccgatt atgaacgata ttctagatca ttcatttgtt caatttcgtg agctactggt
     1981 tcaaagtggc ttaatcagtg gcagtgctct atacattgat ggtacaaaaa ttgaagcgga
     2041 tgcgaataaa tactctttcg tttggaaaaa aagtatttta aagtataagg atagccttga
     2101 tcaaaaagcc cttgaaaact accaacaaat ggtggaaaca aaaatcttac ctgagttaat
     2161 agatgattta aaggatgaac tttctataga agagattgaa aggattcgtc aatctttgga
     2221 agaaaaggaa aatcaattaa ttgaagcgat tgaccaaacc gaaacagtag aagggggctg
     2281 acccattatt aataaggagt ggacaacatg attgatgtaa atgagctatt ggaagaagct
     2341 attagagaaa ctgaaaatct aaatgatggc gaagtttttc ttgttaaaga tttattcaag
     2401 ggatatgtgg ggaataggat acccagaaag gatcgacttc tgcttggaac gttattttta
     2461 aaccatgtta gcaaaatgaa tggtaattta aaggctattg aaaagacttc atctaatcag
     2521 cagaggtata aaaagacaat tgataagttt taactatctt ttgtgaaatt aaaaaaatta
     2581 taaatatgtt gagtagaagc aaaagatttg gcttggaatt tttacagcag tgaatcgata
     2641 aaaggagcat gcttgatggt agataatatt attaaatcag tagcagagaa attatcctct
     2701 ctgtcttata tagaaggtat tgttttaggt ggttcacgtg caaggggcac ccatacagag
     2761 gattcggata tagatatcgg catctattac aattcagaat catttgacat aaatactatt
     2821 aatcaattcg ctacaaagct ggatgatgag catagaaata accttgttgt acctcccgga
     2881 gcatggggtg attggattaa tggcggcgga tggttagtca taaacgggta tcatgtggat
     2941 ttaattttac gtgatattaa acgtgtggaa caaataatga aagatacaga gcacggaatt
     3001 gttactgcca attatcagac tgggcatccc catggttata ttagtgcaat gtatcgagga
     3061 gaattagcga ttagcaaaat actatatgct aagaatgaaa gcttatgcga attaaaaaaa
     3121 caggcagaaa cttatcccaa tgctttgcag aaaagtttag ttaacttttt tatgtttgaa
     3181 gcagggttct ctttaatgtt tgtaaaagca aattcgggaa cagacgataa atattatatt
     3241 gcgggtcatg tttttcgtat agtttcatgt ttaaatcaag tgttatttgc atgtaataat
     3301 gcttattgta tcaacgaaaa gaaagctata aaactgcttg aaacttttga acataaacct
     3361 gaaaaatata ccgagaaggt aaatcatatt tttgaagtac tcggtatctc actttttgaa
     3421 tgctacgaca tgaccgagaa gctttataat gaagtgaatg aaattgtatc ggagataaat
     3481 aactttttaa acgaggagag ttcagatgaa agaaaacaaa tatgatgata atatattttt
     3541 tcaaaaatac agtcaaatga gtcgctcgca gaaaggactg gctggtgcgg gagaatggga
     3601 gactttgaaa aagatgctac ctgattttaa gggtaagcgt gtgcttgatt taggatgcgg
     3661 ctatggatgg cactgtatat atgcgatgga aaacggtgct tcctctgtag taggtgttga
     3721 tatttctcat aaaatgctcg aagtagcaaa aggaaaaacc cattttccac agattgaata
     3781 tgaatgctgt gccatagaag atgtggattt cccagaggag agctttgatg taatactaag
     3841 ttcgcttgcg tttcattatg tagcagacta tgagaattta ataaaaaaga tatataggat
     3901 gctgaaggct ggtggcaatt tagtttttac agttgaacat cctgttttta ctgctcatgg
     3961 aacacaagac tggtattata acgaaaaagg agaaatactg catttcccgg tggacaatta
     4021 ttattatgag ggcaaacgga cagctatgtt tttggaagaa aaggttacaa aatatcatag
     4081 aacactgacc acatatctaa atacactgct ttcaaatagt tttataataa atcagattgt
     4141 ggagccacag ccgccagaga acatgatgga tattccgggg atggcggatg aaatgcgacg
     4201 cccaatgatg ctgattgtat cggcaaaaaa gaagatgtaa taatatagaa aaaataaacg
     4261 aggagtatgt aaatgagatc agaaaaagaa atgatggatt tagtactttc tttagcagaa
     4321 caggatgaac gtattcgaat tgtgaccctt gaggggtcac gcgcaaatat taatatacct
     4381 aaagatgaat ttcaggatta tgatattaca tattttgtaa gtgatataga acctagaacc
     4441 gtttatatct aatgatgact ggcttaatca atttgggaat ataataatga tgcaaaagcc
     4501 ggaggatatg gaattattcc cacctgaaga aaagggattt tcctatctta tgctatttga
     4561 tgattacaat aaaattgatc ttaccttatt gcccttggaa gagttagata attacctaaa
     4621 gggcgataaa ttaataaagg ttctaattga taaagattgt agaattaaaa gggacatagt
     4681 tccgactgat atagattatc atgtaagaaa gccaagcgca agggagtatg atgattgctg
     4741 caatgaattt tggaatgtaa caccttatgt tattaaagga ttgtgccgta aggaaatttt
     4801 atttgctatt gatcatttta atcagattgt tcgccatgag ctgctgagaa tgatatcatg
     4861 gaaggtcggc atcgaaacag gctttaaatt aagtgtaggc aagaactata agtttattga
     4921 aaggtatata tccgaggatt tgtgggagaa acttttgtcc acctaccgga tggattccta
     4981 tgaaaacata tgggaagcat tatttctatg ccatcaattg ttcagggcgg tatccggtga
     5041 ggtggcggaa aggcttcatt atgcctatcc ggagtatgat aggaatataa caaaatatac
     5101 cagggacatg tataaaaaat acactggtaa aaccggctgc ctggatagca catatgccgc
     5161 tgatatagaa gagaggcggg aacagtgatt acagaaatga aagcagggca cctgaaagat
     5221 atcgataaac ccagcgaacc atttgaggtg ataggtaaga ttataccgag gtatgaaaac
     5281 gagaattgga cctttacaga attactctat gaagcgccat atttaaaaag ctaccaagac
     5341 gaagaggatg aagaggatga ggaggcagat tgccttgaat atattgacaa tactgataag
     5401 ataatatatc tttactacca agacgataaa tgcgtcggaa aagttaaact gcgaaaaaat
     5461 tggaaccggt acgcttatat agaagatatc gccgtatgta aggatttcag ggggcaaggc
     5521 ataggcagcg cgcttatcaa tatatctata gaatgggcaa agcataaaaa cttgcatgga
     5581 ctaatgcttg aaacccagga caataacctt atagcttgta aattctatca taattgtggt
     5641 ttcaaaatcg gctccgtcga tactatgtta tacgccaact ttgaaaacaa ctttgaaaaa
     5701 gctgttttct ggtatttaag gttttagaat gcaaggaaca gtgaattgga gttcgtcttg
     5761 ttataattag cttcttgggg tatctttaaa tactgtagaa aagaggaagg aaataataaa
     5821 tggctaaaat gagaatatca ccggaattga aaaaactgat cgaaaaatac cgctgcgtaa
     5881 aagatacgga aggaatgtct cctgctaagg tatataagct ggtgggagaa aatgaaaacc
     5941 tatatttaaa aatgacggac agccggtata aagggaccac ctatgatgtg gaacgggaaa
     6001 aggacatgat gctatggctg gaaggaaagc tgcctgttcc aaaggtcctg cactttgaac
     6061 ggcatgatgg ctggagcaat ctgctcatga gtgaggccga tggcgtcctt tgctcggaag
     6121 agtatgaaga tgaacaaagc cctgaaaaga ttatcgagct gtatgcggag tgcatcaggc
     6181 tctttcactc catcgacata tcggattgtc cctatacgaa tagcttagac agccgattag
     6241 ccgaattgga ttacttactg aataacgatc tggccgatgt ggattgcgaa aactgggaag
     6301 aagacactcc atttaaagat ccgcgcgagc tgtatgattt tttaaagacg gaaaagcccg
     6361 aagaggaact tgtcttttcc cacggcgacc tgggagacag caacatcttt gtgaaagatg
     6421 gcaaagtaag tggctttatt gatcttggga gaagcggcag ggcggacaag tggtatgaca
     6481 ttgccttctg cgtccggtcg atcagggagg atatcgggga agaacagtat gtcgagctat
     6541 tttttgactt actggggatc aagcctgatt gggagaaaat aaaatattat attttactgg
     6601 atgaattgtt ttagtaccta gatttagatg tctaaaaagc tttaactaca agctttttag
     6661 acatctaatc tttt
//
LOCUS       DACBZK010000101         6644 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.106, whole genome shotgun sequence.
ACCESSION   DACBZK010000101 DACBZK010000000
VERSION     DACBZK010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.106"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(1..859)
                     /locus_tag="IVD66_002504"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="IVD66_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="IVD66_002505"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="IVD66_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HAP6146678.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="IVD66_002506"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="IVD66_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="IVD66_002507"
     CDS             complement(2143..2373)
                     /locus_tag="IVD66_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HAP6146679.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="IVD66_002508"
     CDS             complement(2603..3421)
                     /locus_tag="IVD66_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP6146680.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="IVD66_002509"
     CDS             3582..4271
                     /locus_tag="IVD66_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAP6146681.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="IVD66_002510"
     CDS             4285..5787
                     /locus_tag="IVD66_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6146682.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="IVD66_002511"
     CDS             5800..6276
                     /locus_tag="IVD66_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAP6146683.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="IVD66_002512"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="IVD66_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1032 c         1204 g         2236 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atgt
//
LOCUS       DACBZK010000102         6639 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.107, whole genome shotgun sequence.
ACCESSION   DACBZK010000102 DACBZK010000000
VERSION     DACBZK010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.107"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(1273..1938)
                     /locus_tag="IVD66_002513"
     CDS             complement(1273..1938)
                     /locus_tag="IVD66_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6146684.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2064..4100
                     /locus_tag="IVD66_002514"
     CDS             2064..4100
                     /locus_tag="IVD66_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HAP6146685.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4104..4742
                     /locus_tag="IVD66_002515"
     CDS             4104..4742
                     /locus_tag="IVD66_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6146686.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            4770..5198
                     /locus_tag="IVD66_002516"
     CDS             4770..5198
                     /locus_tag="IVD66_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146687.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            5655..6566
                     /locus_tag="IVD66_002517"
     CDS             5655..6566
                     /locus_tag="IVD66_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP6146688.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADNGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
BASE COUNT         2286 a         1005 c         1220 g         2128 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgaggacta cctgtattag tcctcttttt
       61 tgaccagatt ttgaccagtc tattttacat tctaatatat tcatatgagc taattttatg
      121 attaaatggt aagtgtttcc ttgtttgttt tagtttaaac tagtgtgtaa tttaaaaatc
      181 tatatggaag ggtctgtggg gtaatactta aataaaggct aggaacctga taacatcaag
      241 gttcctagcc tttttataat aaaatgaagc gaaaataatt tcttttaaag agccgagatt
      301 atcagctata taagagtgaa tttgatgcaa aaaacagagc cgaaacagtc ttggtgttcg
      361 tagctctgct tatatgtttc gaatttaaga caaagagttg gcaaaagatg ttgataagga
      421 agataagata actgtgttat ataaactagg taactaactg taacaagcta attttaagag
      481 attcttatta gaagacgttt aggaatataa ctaagaaaat gattatacag gtaattgtca
      541 tttcaataat gttttctaat tttcgcgtct ttgttttaag aaaaaggcca gaatcagttg
      601 gaaaaaagtt cgtacgatag tgaagagggg caaaatttcc tactaatatt cccactaaca
      661 agagataaaa cggccaggtt ggtgtgattc ctctataaaa aaatgcccat gctaccgaaa
      721 tcccatagat taacaactga acaattttta caatgaaaaa attgttctgc cattactcaa
      781 agtctcttcc tccttgtatc gtttatttgt ttcattttat cattatgata ggcgcttgaa
      841 caatccattt tgtattttat tgagtactct tggataaact accagcgatt atcatattta
      901 tttatgttac tgtaagccat catataaaag taaatgagca gatcatagaa atataaaaaa
      961 gaactaaaat tgatctaaat tatgtgcagc ttgactacgt accaatctat attacttact
     1021 agattggtcg ttaatctatt cggatcgaat gagcaaaata tttttgtgaa tgtccatcct
     1081 tgattatgat tccaaaaaga atcattggga ggctgtggcg taaatattat actataagcc
     1141 agaaatacct atcattctga acttttttat ttaggaactt tcatctcaag gctttttcaa
     1201 ttaatttgta cccctgtttt ttggataaga tcatgtgcat tgattttttc tatctctacg
     1261 ttcatctcct acttaatgcc tatctggctc ctgagggctt ctttttaagg cgtcgtcata
     1321 gtcttggctg aggatttctt ggtaatctga gggaatggct tcccaagtga gcaggcgaac
     1381 gttcatgacg tgttttcctt tgtgtttgat tacagcatgg tttttctctt tttctacctc
     1441 tccagcgtga aaagacagcc atgtaccatg gccaaagata tcattacata cccaacgttc
     1501 gatggaattg tccacgtatc ctacagggag tgtggtatag ccgatttgtg gtttcaaaaa
     1561 aggattgaat cgatcgatcg tttcattttt gtattgataa ttgataagaa aaagatagac
     1621 caaacaaaag acgagcagaa agaaagatag tgtctttttg agtgagaagg gttgttttga
     1681 tgaataagat ttcttgttaa caagaggttc atctggcaat gttggttcta ttgattcggt
     1741 agctgattca atagaaggaa aatcaatcgg cagacctaaa gtatgatgta aaagtgacag
     1801 catttcaagg tctggcattg tacgagaatt ttcccaacta gaaatcgttt tatcggaaac
     1861 accaattttt tcgcctaatt ctttttgcgt aagcttacaa tttctgcggt aagttcgtat
     1921 tttttctccg gtgttcatct tcttctcctt tcgattctac agtatataga tttattctac
     1981 atgacctata cacttgatag atacgttttt ttgatgaaaa acggtatgat tttatcaaag
     2041 aatcatttaa gtaagggaga gtggtgataa tcaaaaaaaa gttcacagtt ttactcacaa
     2101 tcatagtgac cggtatcatg agtggttttg ccttggttag tataaataaa caggtactct
     2161 atcggacaaa tgaatttttc catcaaacag atacttatac tccgattcga ttgccacaac
     2221 attttattgg gcaagaagaa tatgagcagc taatcatggt atttgaaaat gtctcatcag
     2281 aaactgagct ttcttatatg aaaaaaacag taaatgaatc caatgaagta gatacatctt
     2341 ggaacttcaa gatacagcca aagcttgaaa tgacattgta ttatcaaggg gatgtcaaat
     2401 cttctcacga gaaggtaccc tattctaata cctcctttcg cgtaacgtcc attgaagaat
     2461 cgatcaaaat aaaagatttt gaaggtgaat ttttcttgat gacgagagaa aaagaagcct
     2521 atgaacggtt catttcacta ttcactgatc gattcaatca agcatttcac actgattatg
     2581 ccactaatat ttttgaagac tttgaaaata gctattcgta ttcggttatt tcaaatacag
     2641 acgtatataa ttatcgagtg tatttaacta ttggattgat tcttttattc cttttgttat
     2701 catccttttt cttattgatg aataaagaaa tcagtttatt gttgaataat gacttttcat
     2761 tacatcaagt attgtggtgt ttattgggga aaaagaaaat cattattaca ttcataattg
     2821 caggaatcat tggtggtttt atttttatgt attataagga gcaatttctt tatttgttcc
     2881 agatgtacgt tttcttgttc agcggaatat atggtatctc tttgatttct cttttattag
     2941 ttgaaaaaat cgcttcgtta agagaagcgt tcaactatat ccaatacatt ctttttacat
     3001 ttggattgtt gttttctctt cttttgaccg ttgccaatgt cgaattagca actatcgttt
     3061 tttcttcttc acagttagct gtttcccatg aaccaccaaa agaaatcgct ggtgaggact
     3121 atcatgtatt ttatccagta accatcggga aaaaccacgt ggattttatt tattccaatc
     3181 gttttgcatc agcagcagat caggaattat atgaaacttt gaataaaaac ggaagtatat
     3241 tagtcaatgt atcagattac ttgaatgaag aaaatgaaca gtttggcaga gggataaaaa
     3301 taaatctgaa ttatcttaag aaatttcctt tgattgatgt ctctggaagg ttgatccaaa
     3361 taaccgaaaa agaaacgcac cctgttatat tgatccctga acgatataga catacagatt
     3421 taaaaaatga cctggcgcaa ataacagaat attatcaaga aatcagtgaa aaagaaccga
     3481 aatttctatt tataaaaaac aatcaaccca tttatacatt tattccttct atcccctgga
     3541 tcgaacatta tccggttgtt gaaatactga cattgaaaaa cagtatgtat ttggaaagaa
     3601 atattctcag cggagaaatc tatccaccgt taaagatcaa gataggctct ttgtcgaaag
     3661 aaaggttatt tgagctgatt gaagaaagtc agttacgtga taacttgcag ttatcatttc
     3721 cgtatactca gactgaagag atagctgtca aagtgttaag cagatcattt cattacttga
     3781 tacagatatt tttactcact ttcttttctt tcttcttgtt gagctatgtc atgttatgca
     3841 tatattttgt ctacaattgt cggaaaatcg ctatctttcg ttcaagtggt tattcgctct
     3901 ttgaaacgta taaagatttc ttcatgatga acctcatcaa atggggaacg acaagtgtaa
     3961 tcttcctttt tcttatagaa agagagccta aatatctttt taatattttt ttctttagct
     4021 tcattgattt tattctttca gttgttttta ttttgtctac agaaaagaaa agtcagttat
     4081 tgctgatgaa tggaggttaa caattggagc cgttgatagt gataaaaggt gcgaaaaaaa
     4141 tcattcgaaa caaaacgatt cttcatttgg atcgtttcac tgcggatgct ggggatcttg
     4201 tgactgttgt tggagaaagt ggagcaggta aaagtacgtt attgaatata ttaggattga
     4261 atgatcagtt cagttcagga caattctatt tgttcgatca agagacgaaa caattaactg
     4321 ggagagagaa gcgcttgata aaaagaaata ccatatcttt tctttttcaa gattttgggt
     4381 tgattgaata tgaaacaatc gattttaatt tagatattgg attgaagttt tcgaatttaa
     4441 atgtttcaga taagcgaaca gcaaagtatg aggcattgaa aaaagtaaat ataaacaaga
     4501 agctaagtac gcctatctac acattatctg gtggtgagaa gcaaagaatc gcctgtgcga
     4561 gagtcttatt gaagaatagc aaaatcattt tagccgatga accgactggg tcattggata
     4621 aaagaaataa ggataaagta gttgaaatct tatcgcaaca agcttcccaa ggtacgttag
     4681 ttatcgtagt cacgcatgat ccatatctga ccaaaatagg aaacaagaag atcatgcttt
     4741 aaaaatcaaa aaggaaagga tgtcgtttta tgaaaaaagc agttattatt tgtgcactag
     4801 ggataggttt tgttggagga aacgctatgt catctgaagt ggaagcaaat tcagttcacg
     4861 gtgaaatcta ttacaaatct ttaaagccag gagagattca ttttgatgct aaaggtaata
     4921 ttattaagtc aaatttacca gtagaccggg aaatttctag aacagcaatt aatcatagct
     4981 ctggaagatg ggtttattat agtgatacaa cttgtacgag aaaaacaggt cattctaacc
     5041 actatagtcg tgtctataat cgtcacggtg caaaagcgaa agttggaaac tctattcgat
     5101 cagcaaatgc aacaaaagga gtatgggcct atgcaagtgc gacaggaaat agaactgaca
     5161 cattctcatg ttggtacaat ccaaccggtt ggtattaagt atccaaaagt ttatataaaa
     5221 tagaaaaaac atataatgaa acagcgttaa aagttatttt tggtagtttt aatatattca
     5281 tttttagttg tataaaaata tatcataata aaaacaacaa aaaaatgtct ggaaaatcga
     5341 acataaaagt gtctgatttg aatatcccag cagcggaaga agaaaaacaa aatcgataac
     5401 atttgttcta agaattagtt acgttaaata cggaacgcaa gatagacttg aaaaacggta
     5461 acaaaagaag tagtatatta aggtgtgatg tgctacttga catttattct gctgagcgaa
     5521 ctttctggat tgtgtagcct tatatctatt caggacgtat cgagcagatt agtaaaggtg
     5581 ttcttgatga ttttcatctt gaacaccttt gtttttagca attcgcaaaa aacgaaaagt
     5641 aggagaattg ataaatgaaa aaaagatttt tagcacttgc catcgtacta ggcactggct
     5701 tattgtcagg ctgtacgaat gccggtgaaa aaacagccgt tagttataaa ggcggtacaa
     5761 tcagcgaaca agaagtaatg gatagcttga aaaaaatgca aggagcagat tccgctgtgc
     5821 aacagttgat cgtttatcaa gtatttgaag ataaatatgg agatgacgta tcaaccaaag
     5881 aaatcgattc tcaatatgat caaacaaaga aacaattggg tgattcattt gattcacaat
     5941 tgaaatctgc aggttacaca gaacaaacat tcaaagacag tatcaaacaa agtctagcct
     6001 ttcaagaagg tctaaagaaa catatcaaat tgaccgatga agatttaaaa acggcttggg
     6061 aatctttcca tccagaagtg gaagctcaaa ttatccaagt agcaagtgaa gatgatgcaa
     6121 aagatgtgaa gaaagctgct gataatggag acgatttctc taaattagcc aaagacaagt
     6181 caactgatac tacgacaaaa gaagatggcg gaaaagtgaa atttgattcc actactacaa
     6241 cggttccggc agaagtcaaa gaagcagcct ttaagttgaa agatggtcaa gtttctgatg
     6301 tgatcacttc taccaatgct tcaacttata ctacggaata ttatgtggtt aaaatggtga
     6361 aaaaccaaaa caaaggcaac gacatggata aatacaaaaa agaattgaaa gaaattgcaa
     6421 cagacacaaa attaagtgac agtaccttcc agaataaagt aattggcgaa gtattgaaag
     6481 acgctaatgt aaaaatcaaa gacaaagact ttgaaaatgt tttgagtaca ttcacttcag
     6541 attctagtac agcaagtagt aaataagcgg tataaataaa aaatatgaac tatttaaatc
     6601 aataaaactg ttcatctaaa tctttttatt agaactaaa
//
LOCUS       DACBZK010000103         6539 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.108, whole genome shotgun sequence.
ACCESSION   DACBZK010000103 DACBZK010000000
VERSION     DACBZK010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6539
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.108"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            107..1248
                     /locus_tag="IVD66_002518"
     CDS             join(107..335,335..1248)
                     /locus_tag="IVD66_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP6146689.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
     gene            1483..1935
                     /locus_tag="IVD66_002519"
     CDS             1483..1935
                     /locus_tag="IVD66_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146690.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            1949..2638
                     /locus_tag="IVD66_002520"
     CDS             1949..2638
                     /locus_tag="IVD66_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146691.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            2763..5114
                     /locus_tag="IVD66_002521"
     CDS             2763..5114
                     /locus_tag="IVD66_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HAP6146692.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            5194..5589
                     /locus_tag="IVD66_002522"
     CDS             5194..5589
                     /locus_tag="IVD66_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146693.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            5914..6531
                     /locus_tag="IVD66_002523"
     CDS             5914..6531
                     /locus_tag="IVD66_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6146694.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
BASE COUNT         2289 a          966 c         1309 g         1975 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc gtagaatcta actactaaga aaaggacgtg tccacgatgg caaaagccaa
      121 gaaaaaattt gatgaagact ttaagaagat gatcttagat ttaaaccagt ctggccaatc
      181 ggtcgaagaa ctggcagcgc aatatggtat cgctacacaa acgatttatc gttggaagaa
      241 gcttcataca aagaatgtag caaccggcat gactgaggca gaaatcctag cgatgaaaaa
      301 ggaaatggcc cgcatgcagg aggaaaacac tatcctaaaa aaggctttaa ccatattcgc
      361 tcaaaagtaa aaatgagtga tgtcttcgaa tttattcaat caaatgttca tgatcatgac
      421 gtaaaacaaa tgtgtaccgt tttggaagca ccgaaatcca gctactatga ctggaagaaa
      481 aagaaacctt ccaagcgcca atcagaaaac aaacgcttaa accgcttgat ttcaggaatc
      541 tactttgaaa acaagggtat ctatggtgcg cctaaaattc ataagattct tgttggccgt
      601 ggcgagacct tgtccttaaa gaaagtacaa atactgatga gaaaattagg cttgcgttca
      661 gtcaccctca agaagtacaa gcctggcaaa caagcgaaag ttaaaagtga aggacgtaaa
      721 aacctgttaa accaagattt taccactacg tcgatcaatc aaaaatgggt gacagatatt
      781 acctatattc ataccctaaa agatggctgg acctacctct ccactattca agacctccac
      841 acaaagaaag tcatcggttg gaagtttggc aagcagatga cgaaagaatt ggttatcgaa
      901 acccttgaca atgcgctctt aaaccaaaca ccctccgaga acttgatcat ccactcagat
      961 ttgggttctc agtacactag cgaagcctat gaggcaaagc tgaatgaatt gaacattcgg
     1021 cactccttca gtcgtaaggg ctgtccctac gataatgccg gtatcgaatc gtttcacgcc
     1081 tcactcaaaa aagaagaagt ctatccatca aaagcgtatg aaaactttga agctgcttat
     1141 ttagcgttat ttcaatacat tgaaggattt tacaatcgca agcgaatcca tagtagtatc
     1201 aactatttaa caccaaatca gatggaggag ttggcattgc aagcttagtt cctagctacc
     1261 acttacattt ttttggcgag atttccacag ggtttcaact tcatcgcttc gatcagcggt
     1321 caaacggttt tggtttgacc gctggtcgaa acgatgagat actcacccgc tggaatctcg
     1381 aaaaaattct cacaaatcgt gtccgaggta ttgactcaaa tccaccaatt atcttatcgt
     1441 agatatatat tataaattta ataagaaagc gaggtgagaa tcgtgaaaaa aacgatacta
     1501 agtatttttt cagtatttac aatattaatt gggggctatt ttcttttgaa tttagattct
     1561 gttaattcaa acgctcaaat aaaagatcaa agagtagctg aacataataa taaaaaaatg
     1621 agtttgacca aaaatatcta ttctatgtca gatgaagaat tgtataaaga atttggtgat
     1681 ttatccgggg aacagttaga agaaagtatt ccaggaatta gtgactcaga taaaattgtt
     1741 gtcttgtctg ctggtgggca attaatggga gatggcaaat ccgaattagt tagttataaa
     1801 caaaatcaca gacagtttat tgatgttaat actgattcca acgctatttc gattaaggat
     1861 ctaaaagagc ttttaaatag taaaagaaat gaattaaagc agataaaaga aactaattca
     1921 gtggaattag agtaaaggaa gattcattat gaaaaagatt tttggtgttt ctgttgggct
     1981 acttatgatg ttaacatttg gaaatgcagt atatgctgct gagaaagaag ttatttcaga
     2041 tccagagcag tacgcctcac gatactttgc tgattttgaa gaagaagata aagtacttgc
     2101 attgccagaa ggtggttttt taaaagggga agctaaaatt gtatctatgg ataatccaga
     2161 tataattcaa ggttcatata attcagaaac tgatcctgct tcagtttcag tgacagaagc
     2221 aaaaaaaatt gttgctgaaa aattcaaaaa tgatattgaa actactccaa ttatgcctcg
     2281 aggagcattt ccacccgatg ttggtactag cggacacctt cttgtactag caggaggagg
     2341 aagctataaa tcacagccat ttagtggtgc gggatggcgt tttggaggta tgggtgtaaa
     2401 accagctgat ggtacaggca actttttacg ttggaaatcc tacattgacg atggaagagt
     2461 aggaaatgta aatcaagcca acgcaactaa atctggttct attcaaggaa tggcattgta
     2521 tgctcgtgaa ggattcaaat actttgcacc aaacgggcct ggttggacaa tgaatatagg
     2581 tatttattac acttataatc ctgttgcagg tacgtattat gttgttcaaa atatttaata
     2641 aaacagcaca aagagatttc tttgtgctgt tttattattt ttagttgttg acaaacacta
     2701 aaatataaaa tataatcaac acataaacga acgtatgttc ggcaagaaag caggggattt
     2761 ttatggatga gatggtttta agtactcaga aatggctaaa caagaaatac agtaatgtta
     2821 cagggtttga taaggttcca gaaaatgggc gaacagggtg gcctacaatc tatggactta
     2881 ttgaaggact acaagtagaa cttggtatta ctaatctagt agctaatttt ggacctacca
     2941 ctgaaaaaat gtacgataat caggttactc ctaaatgggg caaaaatcta cctaaaaata
     3001 ttgtatttct tattcaaggt gccttttggt gtaaggggat taatccaggt ggcttcgatg
     3061 gggtatatac tccatattta gatactgctg taaaagagtt gcagactgat gcagggttta
     3121 atggaagcgc tgtaactgga gttttggatg cgaaatgggc caaagcgtta tttgatatga
     3181 gtgcttttgt tcttgttccc ggcggagata gtaaaattag aaaaatgcag caatggttaa
     3241 atgtaaatta tttagaatac acgggaataa tgccttgtga tggtatttat caaagaaatt
     3301 caaatcaagc attaattttt gcattacaag ctgaactagg atattctccc agtgaagcaa
     3361 cagggtctta tggtaatggg acaactagta aaacttatcc tgtgtctgaa ggtaactcgg
     3421 gaaactatgt aagaataatt caatatggat tatatgttaa tggttatttt gaagacggta
     3481 cattcgatgg tattttcact aaatatatgg gtttagaagt actggcattc cgaaaattta
     3541 tggtattgcc tgaatatact gaaatagcag atgttgttgt aataaaagga ctattgtcta
     3601 gcgctggaga tattagaaga tctgcagatg gcgcagatac ttctacgcaa ttaactagat
     3661 ctcaaatcca aacattggtt gataatgata taaaaatagt tggtagatat cttactggta
     3721 ctgttggaat tggaaaagat gaacgaaata agtatctaac tacagaggaa ttgaataata
     3781 ttttttctaa aaatttatct gtgtttccta tctatcaaga tggaggtgca gcattagctt
     3841 attttactta tgatcgtggc ttatcagatg gtaagaaggc tatagatgca gcaaaaaatc
     3901 taaatatacc attaacaaca gttatttatt ttgctgttga tctagacatg ttaggggaag
     3961 aaattcttgc atatgctgga gaatatttta agggggtatc tgctgtaatg tcatatagcg
     4021 ggtatcaaac gggtgtttac ggaacaagaa atgtttgttc tcaaataatc aataacgggt
     4081 atgcttcgtt tgcatttgtt tcagatatgt cgactggtta tagtgggaat ttaggttttc
     4141 ctatgcctag acaatggtct tttgatcaat ttgttgaatt taccatagga agtggcaacg
     4201 gagctgttgg tatcgattta atcgctacat cgggtagaga tagcggattt aatgagttat
     4261 caaatgatac taataatgat aattacattg ccaaatacaa tcagaaggtt ataaatcaga
     4321 tggtacgtgc gtatcaatat ctatcacaag ctggtcttga taatccttgg aaccctcatt
     4381 tgacatttta tagatatgta aattattctg gtttgtcatg ggacatcatt tcttctcctg
     4441 taacagagca tgatagaaaa atttatgatg aatataggaa taaattaact aatagcgagg
     4501 gcctgtataa ttattttata gatcctaata ctggttcaat aataggtttg cctcacttaa
     4561 ttgtgacgtt acaatcacag atgtttctag ccgacacaat caatgatagt gtttctgact
     4621 ttgcaggttg gttaggagat ttaatgactt gctggggtga agttaagaaa ttaggaatac
     4681 aaatggagca aggtgtattt gcattagtag gtacggctgc aggtggaaca tttagtctag
     4741 aagatttata ccaagatgtt gacgcggtaa atgtttatac cttagcaaaa agaaattctg
     4801 attcaacagc tttatcggct ttaaaaacgt actattgtga taagggtgct attgatagat
     4861 ttaatcaatt tgttaagaac agatttggtt cttcagataa aatcgcttca gtaacaaata
     4921 gtttattaga aaatgacgaa acagttgata tcttaggtgt agggataatt tcatttttca
     4981 ttgataaaat agttaataat tcacttggga cagattttac ttatcttgat tttattggag
     5041 atgaggggaa agttgcaaat ggattttctg aaaaaattat tcaatttcaa gaaaatagaa
     5101 gtaaacttaa ttaagaatcg tttactattt aaacagtgtc cttttccttt ttaaatatat
     5161 acgataaaat aagtatatga attgtaaaag gacatgatga ttatggaaga aatagaatgg
     5221 aataatctga ctcaaaataa taaaaataat tctggatgtg gaattatctt tatgtttgtt
     5281 atagttttgg gaatagtagt acttttaata actgtcaaga tagtagatta ctttgcgaat
     5341 actcctgaag aacaaataca gagaaaactt cctgagtttg aaagagtacc accttatgat
     5401 ccaagagata attcatttca agtaaaaaaa ttaaaagagt ctccaaatga aatgtggttt
     5461 gaagttacag ttgaatcaag cgacttcaaa gaaaaaaaga aagaatacaa ttatattgta
     5521 aaggcaaaag tatcaaaaag atttattttt aaccctaaat tagaaatata tagtgttgta
     5581 atagaataat agtgttaaaa aaattgtaaa agttaaagaa gtcaaattct gatgtgaaaa
     5641 ataaaatata ccatggaaga cataaaagaa aaactggata actagtttat ttaatggcag
     5701 accgttaagg cctgccattt ttatgtattt tagcggaata aatataatca tgcgggagtg
     5761 taaacttact gtttcaaaaa gtatactttt tgacatgcct tgattttctt tgtttatgta
     5821 tggcataata accacataat acaatttgaa acgtttctga tttaatctga ttgttttgaa
     5881 acaattttag tgaaaaaagg gtagataaaa acgatgagaa aattttttta tatccgggtc
     5941 agtagttatg atcaatcgat cgaacgacaa ctgatttccg cgaaggaatt aggaatccct
     6001 gaagaatata tatttgtaga aaaagccagc ggcaaagatt ttaaacgccc tgaatatcaa
     6061 ttaatgaaac ggatgtttcg aaaaggagat ttactctatc tacaatcatt agatagacta
     6121 ggcagaaata aacaaatgat tttagaagaa tggcgagaat taactaagga aaagcagatt
     6181 gatatttctg tgttagacat gcctctgtta gatactgcta gttacaagca actagatggg
     6241 ttagagacgc ttatctctga cttaattctg caattactca gctatatggc cgaagacgag
     6301 cggaaacgaa ttaatagccg gcaaagagaa ggcgtagaag ctgcgaaaca aaagggtgta
     6361 aaattcggca gaaagaaaat tgctttacct cctgaatttc ctgcgatcta ttctgactgg
     6421 aaagcaggaa agataactgc agtctatgct atggatcaat tgggcatgaa acgaaatacc
     6481 ttttatcgac gggtgaaaga atatgaacat accttgcacc acttttcttg atagatata
//
LOCUS       DACBZK010000104         6529 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.109, whole genome shotgun sequence.
ACCESSION   DACBZK010000104 DACBZK010000000
VERSION     DACBZK010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6529
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.109"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(216..503)
                     /locus_tag="IVD66_002524"
     CDS             complement(216..503)
                     /locus_tag="IVD66_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP6146695.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(493..822)
                     /locus_tag="IVD66_002525"
     CDS             complement(493..822)
                     /locus_tag="IVD66_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007723369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP6146696.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            1127..1456
                     /locus_tag="IVD66_002526"
     CDS             1127..1456
                     /locus_tag="IVD66_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6146697.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(1743..2228)
                     /gene="vanZ"
                     /locus_tag="IVD66_002527"
     CDS             complement(1743..2228)
                     /gene="vanZ"
                     /locus_tag="IVD66_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HAP6146698.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(2381..3292)
                     /gene="vanY"
                     /locus_tag="IVD66_002528"
     CDS             complement(2381..3292)
                     /gene="vanY"
                     /locus_tag="IVD66_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HAP6146699.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            complement(3720..4328)
                     /locus_tag="IVD66_002529"
     CDS             complement(3720..4328)
                     /locus_tag="IVD66_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HAP6146700.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(4334..5365)
                     /gene="vanA"
                     /locus_tag="IVD66_002530"
     CDS             complement(4334..5365)
                     /gene="vanA"
                     /locus_tag="IVD66_002530"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HAP6146701.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPTRSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(5358..6326)
                     /locus_tag="IVD66_002531"
     CDS             complement(5358..6326)
                     /locus_tag="IVD66_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HAP6146702.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
BASE COUNT         1945 a         1355 c         1080 g         2149 t
ORIGIN      
        1 actaaaaaac aatataaaat aacgcatttt aagccctctt tgtgcataag gatgaagctt
       61 ttaatttgaa agaggcttaa aatgcgtttt aattttttct atttttcata aatatatagg
      121 ttagtggttt aaaattatag ggtattacaa ctctcagctg ttaaaaatta tcttttaaag
      181 tgtcgtctat cctctcaagt tgaaacattg ggttcttacc taatcttttt taattgttca
      241 taaaaatttt catgcgttcc acatagtaag ataggtatca ctgcattatc tttaatttca
      301 tatgcaacgc gatatgtcgt acctgcatac ttgaatccaa tagcccaaat tcctgataaa
      361 tcacccgttt tttgttctcc cgaatgagga cgaactgcta tctcatcata aattatcgtt
      421 aaaaattgtt cttttaatgt tttctctttt aattttttta gatactttat tacgtgttta
      481 gaaggtagaa tctcataagc caatttctgc tgccaactcc tcttttgtca tcggtttaga
      541 atttgcaaca gtatcttcag caatagattt aaatgcagaa gttaacgcat tttttctatt
      601 tctaaattct tttaagatct cttgtttgct ataaccttct gaaagaatat cagccaaaat
      661 atcttcacta aaatcaaaaa attctttttt aggctctaca aactcataaa ggataccatt
      721 ctctacaagc ttagcttcta cttcaacacc attgggcaca tcgaattctt tagggaccgt
      781 taacataata gaatttcctt gttttcttgt ttttgtaatc atattatttc ctccattatt
      841 ttacatttcg taattactta gtaattacat tgtacgctat ttttagtaga aatacaaaat
      901 aataaaactc ctttagaaca attttcaaag gagttttatt tgattaggaa attatgtaga
      961 ataataatat gtttttaact tggaatcaaa aacgcacttg caagtaagtt tacttcaata
     1021 catgaaattg cttataatag tgtattggaa ttaaggtaga ttgacaaaag agtgatcaaa
     1081 taggtatact tcattcaaat aatcgtttga atgtgaggtg agatgaatga aaaaagtttg
     1141 ccaagtgact gtcgtacata aagaaaaagt aaatggaata aaaaataaat tggatcaaaa
     1201 agatttttca aacttacttg tgttagggaa atgtttcagc gatttttcta gaattaaaat
     1261 tttctatgct ttagaaacct ataaggaaat gtgcgtctgt gatttagcag aaatacttac
     1321 tgctagtgtc gctacaacgt cacaccattt acgtttttta aaaaaacatg gaatggcaaa
     1381 atcacgtcaa gatggaaaag tagtttatta ctctttagcg aatgaagaca tcctttccgc
     1441 tattcgtgtt ttttaaagtt atcagaaaat ctatctatga aatcttagtt tgggggtacc
     1501 gtcaggaaaa tgcggattta caacgttaag gaaatttatt aaagagacca attcctcagc
     1561 actaaaattg ataattgggc tttctttgtt actatagtgt taggtaagct ttttacttta
     1621 tcaccggttt tcccctcact tcacacctac gggcgagttt ccccacatcc cgttttccat
     1681 ctaatccaat tcattcaata tctttatgtg tatgaaagat cagattgctt gatttagaca
     1741 tcttacacgt aatttattct taaatgggta cggtaaacga gcaataatac gagcaaaagt
     1801 atacctacaa aaataataac tctgtctaat tttttttgat tcatatgctt attgcttaaa
     1861 ccatataatt tcagtccaag aaagcctcca acagtatttg taattacatc tgttatgtct
     1921 gtcgctccaa tagcgaagat aaattgaatt atttcaaaag taagacttaa aaccagtaca
     1981 aaagcaaact taggtaaaaa tccgatttct ttaaaattga cattcaaaag caagccaaat
     2041 ggaataaaga ttataacatt atctatcatc tctctgaaat tcccagtagc agtaaatgga
     2101 gtcaagttaa gacttctttg atgataatta aatactgata aaatattgta ttgtaatttg
     2161 aataacacta accagattag tgtcactaaa tataaagcta gcaatcctct agataatatt
     2221 tttcccaata taatttcctc taattctttt gtttaagttg tatcattagt atagcaatgt
     2281 cctagttaac gtgggtttta aattaaaaag ctaacgttac cccaaaagtg ctagtacaat
     2341 aatgctgttc attaatttcg ttggtttcat tccgccatcc ttacctcctt gaattagtat
     2401 gtgttgatcc gggaaacact gtcacaatta caccgtctat attgtttcct gatatctcat
     2461 aacgaagatt agtcggcaca tgaatggtgg tatttttagt aacaggataa taaaagatct
     2521 catatttttc cccatttaca ctaacagaaa tggttttttc ttcttttagg taatccatat
     2581 attcctcgag aacgaaattc ttttctttca taatcgcact atgtggtaaa ccaacatagc
     2641 gaatatgcca tagttcatat tgaattcctg ttaactctgt tttgtcctct ggataacgta
     2701 aaatgaaccc gtatttccaa gcattttctt ctatccactt tccttcaggg gctcgttcca
     2761 ttttcgtcaa gcttgatcct acatctagtg ataaacctga attatgctca ctataacctg
     2821 ctggtaaggc atactcagcc cccatttctt ggtaaagcac actttgctca tcaaagtctc
     2881 gatagccact attaataata aaatgactaa cgccaccctt tacagcatca ttgaccatct
     2941 ctgaaaattt ttgtgctatt tcttttgaca tataaatatt actatcaagc aacccgtatc
     3001 catttattaa ttcgtcatgt ttagataaat tcacgatatc tgacttcaca ctttcttggc
     3061 gaacaggata tttactattg attaatagca gatttccttg ataaacctgt tcttctgtaa
     3121 ttgttttctc ttgggtattt tcagaagtcc cactattttc taaatgttct ttgggatttt
     3181 gatcataatt ttgaaattcg actttttcct gagaaaacag tgcttcatta acgtagtcat
     3241 aacctaagta tattaagaat aacaataaca ataaaaaaaa caacttcttc attttcagtc
     3301 tcctccttaa ctatatagtt ggaagtatga aatatttcta gaatcttccc cttaaacggc
     3361 acaatctcgt ttgagattgt gccgttttgc cccgtaaatt acagtcaatt atttcgccct
     3421 actggattta ctattatcac caatgtagat gaattttcat aagtgatacc catgctgaat
     3481 ttaacgaggc tgaactgcct gttgacaatg ggcggtgtga aataccaccc ctctatgcga
     3541 tcagtcttat tatcaggcta tcttgccgca gcgcacgcag ataatgaccg caatatcgct
     3601 ctgccttaca tcttcaatac tatctactat atataaattc cctaagaacc agttacatac
     3661 gtcgggtttc ctgccgaaag agttagctta tatagtttgt ccgtgcaacg gttaaaagtt
     3721 tatttaacgg ggaaatcaaa atagctattg gggtatggtt cgtctcttaa tacatagtgc
     3781 caccattcga ggctatatgc ttcaaaccca ctgttttcca tgatggagcg caaacgtctg
     3841 cgattttgcg cttcattgca tgatattcca tttgccgcat gatgagagcg ttcatccata
     3901 aaatcaaatc ggctccccat tggtacaagc tcacccgtgt ctaatcgata aagcgtaaga
     3961 tcaatggcac tgccgcggct atggcttgat tttgaagcca cgtatccttt tgaaatcatc
     4021 tcagttcggt caatattggg ataataactt tcctttgtca ggttattttc cggctgtgca
     4081 gcccattgca taaaacagtt tacagcacga ttaggacggt aaccgtccca tagaagcaat
     4141 ccgtaccctt gggtagcagc cagttctttt gccttcaaaa gcgattcagc caactcgtat
     4201 gtccctacaa tgcgatttac ttcataaccg tcaaccggtt ttccggtgaa attatcccaa
     4261 gtggcatatt tagcgtccca acgaacaccg tgtactattt catctaaaaa agtaaatcct
     4321 atttccatgc ttatcacccc tttaacgcta atacgatcaa gcggtcaatc agttcgggaa
     4381 gtgcaatacc tgcagcggcc atcatacggg gataacgact gtatgacgtg aaaccgggca
     4441 gagtattgac ttcgttcagt acaatgcggc cgttatcttg taaaaacata tccacacggg
     4501 ctagacctct acagccgagc gctttatata ttttttttgc cgtttcctgt atccgtcctc
     4561 gctcctctgc tgaaaggtct gcgggaacgg ttataactgc gttttcagag cctttttccg
     4621 gctcgacttc ctgatgaata cgaaagattc cgtactgcag cctgatttgg tccacctcgc
     4681 caacagctaa cgcggcactg tttcccaata ccgcacaacc gacctcacag cccgaaacag
     4741 cctgctcaat taagattttg ctgtcatatt gtcttgccga ttcaattgcg tagtccaatt
     4801 cgtccgcgct attgactttt ttcacaccga aggatgagcc tgaacgcgtc ggcttaacaa
     4861 aaacaggata ggtaaacgta gctgccaccg gcctatcatc tttattaata acccaaaagg
     4921 cgggagtagc tatcccagca tttttcgcaa cgatgtatgt caacgatttg tccatacaaa
     4981 ttgctgagct ttgaatatcg cagcctacaa aagggatacc ggacaattca aacagacctt
     5041 gtatggatcc atcttcacct gacttgccat gcaaagctga aaatgctaca tcaacatggt
     5101 tgatttcata ttcatggttc tttttaacaa gtaatccgtg cattttttta tccggcgaga
     5161 gtacagctga atagcaattg tcgttttccc attccgcgca aggtttttcg cacattttcc
     5221 atacaccaga tttcgtaatt ccaatgtata acggctcgta tttttcttta ttaatgttag
     5281 cggctatctc tattgcagat tttaccgata cgtcatgctc ctctgagcaa cccccaaaca
     5341 gtattgcaac ttttattcta ttcatgctcc tgtctccttt caaaatccaa acagttttta
     5401 atggtttttt caacggtatc acgcaacgct tgctcggtat aataggccgt atgcggtgtg
     5461 attatcacgt taggcattct ttgaagttta agtaaaaatt gattatcaat tggtttttgg
     5521 gtgcaatcag agtagaaaaa ctcttcctct ccttccaata catccaatgc ggcaccgccc
     5581 agtttcccgt tttctaatgc tttaaccaac tcataggtat ctacaagtgg accgcgccca
     5641 gtattgataa gaaatgctcc ttgcttcatt ctctgtattt gttcgtggct gataatatag
     5701 tgcgtatccg tattgagcgg cacatgaagc gtaacgatat cgctattttg cagcaactca
     5761 tcaaacggta catagtttac ctctatactt cggctgcgac tataagccaa cactttacat
     5821 ccaaatcctc gcagccgctc aataaccgct ttgcctatct ggcccgttcc caccacacca
     5881 actgtcatgt cgctgagtac cttgccacgg tcgctgtcca acctgaaatc atgtttttcc
     5941 acagagcgca caatcgattt tacgttgcgt actgccataa gaattagcat catagtataa
     6001 tcggcaacgc tatccggcga gtacgccaca ttgtcgacag tgatgcccat tctcttagca
     6061 gcagttgtat ctatatgatt gcagccgatg cttcgggtag aaatatattt cacaccggct
     6121 ctcttcagcg caagaagaat agaggcggaa atctctgatt tatgtcccac actgatacat
     6181 tgattgaaag gcgcggattt ggcgttggat tccgacacgt tggcgttaat tatcgttgcc
     6241 ataacgccaa agcgaggcga aagagcatgg aatgcatctg cctcatcctg ctcacatcca
     6301 taaacagtaa tgccgatgtt attcataatt aagaccaacc ctttctgtga aaggcaccaa
     6361 ataaaacggg gatgccaatg gtaatcttgt caaatctttc tctgaagaac gaaaacggct
     6421 cgttcttacg gtattaagtc taccgtgtaa gaacgagccg tttcttaata ttaaattgtt
     6481 aatttcctaa gaaaaagtaa agataacctt gagattttcc taaaaaatt
//
LOCUS       DACBZK010000105         6460 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.111, whole genome shotgun sequence.
ACCESSION   DACBZK010000105 DACBZK010000000
VERSION     DACBZK010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.111"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(105..560)
                     /locus_tag="IVD66_002532"
     CDS             complement(105..560)
                     /locus_tag="IVD66_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146703.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(714..1922)
                     /locus_tag="IVD66_002533"
     CDS             complement(714..1922)
                     /locus_tag="IVD66_002533"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAP6146704.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(2034..2366)
                     /locus_tag="IVD66_002534"
     CDS             complement(2034..2366)
                     /locus_tag="IVD66_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAP6146705.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            2514..3389
                     /locus_tag="IVD66_002535"
     CDS             2514..3389
                     /locus_tag="IVD66_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP6146706.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(3471..4052)
                     /locus_tag="IVD66_002536"
     CDS             complement(3471..4052)
                     /locus_tag="IVD66_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HAP6146707.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(4058..5317)
                     /locus_tag="IVD66_002537"
     CDS             complement(4058..5317)
                     /locus_tag="IVD66_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAP6146708.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(5319..6365)
                     /locus_tag="IVD66_002538"
     CDS             complement(5319..6365)
                     /locus_tag="IVD66_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146709.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
BASE COUNT         1797 a         1338 c         1102 g         2223 t
ORIGIN      
        1 cttgtcacag tcccttattc tgaataaacg gtgtggaaga gacagcctat cagtagtaat
       61 aagacacatc tctttcacag cctcattttt gcgtaaaaat cgatttattc gaaaaattcc
      121 ccgtatacat cttctacacg ttgatctgga ttgatcacga tatacaagtt acctgttttt
      181 tcgctgattt ttgttgattg atattgattg tctaatcctt ctgttccttt atctagatat
      241 gggaagtaca caagatcagg tgtgccattt cggtaaagga tttccattcg ctcgatatct
      301 tcgtatttca atgcgcgatt aaacatgccc atttccagtc cgcctaggtt gatatcatgt
      361 gtcgcaactg cgtccccttc atggaagatt tcgattttaa atccagcaca cggatggatt
      421 tcaacaaatt cactgccatt gattcgtcca aaacttgttg tgatttgttt gatccaaaga
      481 tcgccgatat gacggcggtt gatcgtccag gtttctccat ttctaaaata aaattttagc
      541 gctgtcattt ctttactcat taaaaagact cctttatgat gtaatttatt cttgtactac
      601 ctcagtttag cacaaattta tgtaagtggt cacatcttat gttttttctt ctaatgacgt
      661 atctgcccac tttaagtagc caacaaagct gagcagatac agtctagtgt tttttaaatc
      721 aatttttctt tcgataaaaa atccaaaacc tgttttttat cattttttat tctttgttct
      781 acgacggctt tttcagctaa ttgcaaagct tcactaaccc acttaccagg tttttttcca
      841 gtttcttcta gcaagatttt accatctact gctaattcgc ttaatgactt gataggtaaa
      901 cgatcatagg attctcctac ggcatccatc tgaggtgttt cgtcaaaata gatcatcaat
      961 tcttctactt gcagtgcatg ttttttgcct aagaagtaca attcgaatgg ttccaaagct
     1021 ccagtttctc gttgtcgtag tccttggaca agtgcttgaa cgtctttaat catttggtta
     1081 gaacacttcc acgatttcaa aaaggaacga atctcatttt cttttagatc cagttggctg
     1141 atcaataatg cccatgcttg gctctcttct ttcaatggga cggatggtaa ttcagcaaaa
     1201 cgtaaaagtg cttcgccttc ttctttcaaa ccgggacagc aaatgtagca ctctgtttca
     1261 ataaatgcat ggattcccgc ggcccgttca tttcccaaga gcatcttgat gaattccaca
     1321 tttatacgtt ctacagatat tttacctaat agctcgtggt tttctttgat ggcgtagaag
     1381 gtttcttcct ctaatttgaa ccctagttga ctgacaaaac gcaacccgcg catcattcgt
     1441 aaggcatctt catggaaccg ctcatgagga ttgcctacag ctcgcaagat ctgttcttct
     1501 agatcttgca gaccatcgaa caaatcgatg atttctccat cttctttcaa agcaaacgca
     1561 ttgatcgtaa aatctcttct tttcaaatct tctgccaacg aacgaacgaa ttcgacatga
     1621 tctggtctac ggtagtcctg ataagttgat tccgtccgaa atgtggtgat ctcatattgt
     1681 tcatcatttt ctaataccaa cacagttcca tgttcgatcc caatatctat cgtttttgga
     1741 aaaagctgtt tgatttcttc tggaaatgcg cttgttgcga tatccacatc atggattggc
     1801 tggttcagca agatatcacg aacacttcca cctacaaaat aagcttcata tcctgcattc
     1861 tctaattttt tcagaactgg aattgccttt tggtattcca gaggtaattg ttttaatttc
     1921 atttttccaa cctttcctgc gtgtttcttg tcctgagata aagactcagt tgcatggtga
     1981 ctgtttgaca agtccgtttc agagtcttca aggccaggac cacttcatct tgtttactcg
     2041 tccttacgct caaagcgatt atggtctctt tgattgaatt tttccatgtt tttttcaaaa
     2101 acttcagtta agtcgatatt caatgaatta gccatgatca tcgtaacgaa taaaacatca
     2161 ccaagttctt ctgctaccga gttaactggt tcagaagcct ttttgctttt ttctccataa
     2221 gtgtggttga cttctcttgc caattcacct acttcttcag ttaatcgagc catctgagct
     2281 aatggagaga aataccccac cttgaattgc tggatatatt catccacttc ctgctgcata
     2341 ctgtataaag aacgcttttt atccatcttt ttccctccaa aactatctta ccaaaacttt
     2401 aacgcaaatc ctagataaga gcacttgaga aaatcgaatt tccatgctac atttaggaag
     2461 gaatttctaa atggaaattc tgtgaaaata cataattgaa agctggaatt catatggtca
     2521 aacgaaaaac agtaaaagaa gttcttttta tcattatagg aacaagtatt tatgcatttg
     2581 gtcttgttta cttgaacatc gctaatcatt tagcagaagg gggagtctca gggatcacct
     2641 tgatcttaag agctttattt ggtattgatc cagcttatac gactttatta atcaacatcc
     2701 cattgatttt actaggagga aagatcctcg gtaaacgttc cttggcctat actgttctag
     2761 gtacactttc tttgtcattc tttttatgga tctggcaaag ggttccacta gaaatcaatt
     2821 tacagcatga tctactgatc gtttctctac ttgcgggttt agttgcaggt gtaggaagcg
     2881 ggatcgtcta ccgcatgggt ggaacaacag gcggcagtga tattatcgct cggattttag
     2941 aacaaaatta cggcatcact atggggcgtt ccctattggc atttgatatc atcgtcttac
     3001 ttgcttcatt aacctatatc gacttgaaac gtatgatgta tacgttgatt gtttcgtatg
     3061 ttttcagtcg tgtgattgat tcgatcttag atggcggata ttctgcaaaa ggtctacttg
     3121 tcgtctccaa caaaagcgaa gagattgcac cactactgat gaccggtctg caaagaggtg
     3181 tgactttcct ttctggagaa ggcgcattct ctggtaattc aaaaaaaatc atctatatgg
     3241 tcgttagctc tagtgaatta actgaagcta agaggatcgt ccacgagatt gacgaaaaag
     3301 ctttcctttc aatcatcaat gtgcatgaag tggaagggca aggctttact tatttgaagc
     3361 cacagacaag attactgaaa aaactataag aaaaaagaca aagataggct atgaggaaag
     3421 attccacatc cagctgacct ttgtcttttt tagtactata ctatttttaa ctaattgtta
     3481 tgttcactta cccggttact tttcttttgt gtctgcaaaa ggatctttcg gttaacttca
     3541 tcagataatt tcaaaaaagc atccctatct ccatcttcta gtgcttgatc gatttgagca
     3601 taaagcattt ttagttttgc ctcttcttct ttttcttgaa aatatcgttc aattaattca
     3661 gtatcttctt cactgactga agaatcccaa gaagaaaatg gattgtcttc taagatagat
     3721 agatattctc ttgtctgcca agcattttcg aatatacatt ccacatataa aggctttttc
     3781 caattcaaac ggatttcatg aaaaatctgg tctgtgtccg taaattcttt tccctgcaaa
     3841 aacaatttca tgggttcccc ttcaacagat agatcactga tctgcagtcc tcgatccgca
     3901 aaattcgccc cttcaacaaa gtggacattg cttaaaatcg cttcatgatt ggcaagataa
     3961 ttcaagatcc aaaaaacttc tcttcggcta aaagatacat gattgaccat ccacgttaaa
     4021 aaattcttct tttcccgtac atcaattagc atttttctca cctctctgtt aggtcatcta
     4081 ataatgacag tgcctccata tctcctggtt caagtgttaa ataataagtc aataattctt
     4141 gcgctctttt cagctgccct tcttctctta agaaaaaggc atactctttc aagaaatctg
     4201 gttcatgtga tagttcatga taagcctgtt catagtgtac agctgcaacg gtaaagtctt
     4261 ctaattcatt ataagcatgg gctaggttcc attctgcata aggattagca gtttcttcca
     4321 tctgattgat cacttgtatc acatcttcat atctttcatc atccaagtaa agattactta
     4381 aagtaagtaa tgtttcatct tgtttgtctc ctacttctaa agctttcagt aaaagttctt
     4441 ctgctcgctg tctatcatgc agacggaaag cattttccga ggccaggtga taaagttcga
     4501 cttggtaagg attttctttg attccttctt ctaacactgt ttgtgcttct tcaatcattt
     4561 cttcttcttg aagagcttgt cctagatata gatataacga ttgataatgc ggattaactt
     4621 ctcgaagttc ttccagatag ttgattgcct gctgattttc tttcaattga agattcgtaa
     4681 aagctagctg gaacagtcga tcatctgtcc tttcttcttt cagtgcttct tctaaaggta
     4741 cgatagctgc ttcgaattct ccttgcatac ttaaggattg tcctaaacgt tcctgcatcg
     4801 agattcctga aatttcattt atcccgcttg ccaacaatgt ttcataaacc actgctgcct
     4861 ctttgaaacg atcaactgaa aaatacaatt cagctagcgc aaactggatc aatggttcat
     4921 caggaagcaa cccagctgct tctttcaatt ttgcttcact cacttcaggg attccgataa
     4981 cttggtacaa atcagctatc gccaataagc tttgcggata gtaatcactt tgcttatcca
     5041 ctttttccag gtattcaaaa gctaagtcga tctcattatc ttcgattgca atttctgcta
     5101 acgggatgtt cagtccgtca ttttctgggt attggttgat cagttgttca aaaatctgtt
     5161 ttgcttcgat caaaaagcca atagccagca attcttcgcc tagttcagct aatatatctg
     5221 ctgggtcttc ttttaatgct ttttctaaaa agatttgtgc ttgtgacaag tcttcatctg
     5281 ataaagcttg caacattttt tcgctatttg tattcatttc aattccctct tatctcactg
     5341 acgatttgtt gaaataccgt cattgttctc aataattctt tttcgtttgg atgttggtat
     5401 ccgtctatta tacctatttt ttctaaaaca agtatttttt tgcttttttc tgccaaaaaa
     5461 agaacttttt ccaaatactc catctttgaa atctgttcca gccagtggat tggatagcca
     5521 agcaagtcca gccacacaaa aaagtttttt agttggaaat caaaaggata tgcttggaga
     5581 ttccacacga aatgaaacat cattcctaaa aattttttca tactagcaga aagtagatgg
     5641 ccattttcgg tcagataaaa agcttgttca aacagtttac cataatttga caggttttct
     5701 gcctctaatt gataaaaata gatcatttct tcgatcatcc cggcaaacgg ccgagtcgtt
     5761 aattgctttt tatttggata gtttttatac agattttgca aaaaacgatg atcacaaatc
     5821 attccgcaac agataaaagt caaaaagtca atctgctttc cgtccacctg ccgctcgctg
     5881 attgtttgat cataaacgat gcgttctggc agattgatgg tttgcagcac tacacgattt
     5941 ggtagctgca aaatcgtccg ctgcggtgtt aatgctcggc ttagagaacg gatcgataca
     6001 gggatcatcc atagtgatga atcaagggtt gtatgttttt gaaaaaaacc tgccagatcc
     6061 atgatccctt catttccaaa tccgatgata aacatggatt gattttcggg atagcgtttg
     6121 acgaaatcaa gcaggttctt taattctgtt aaatgattgc attgagtgtt ggcacaaata
     6181 taccagtcat tgtttgcttg atttgcaaat aacgggttga tcttatctgc aaacaaatca
     6241 taatagcgct gattcgttaa aaataagatt ggctgatcaa tggaaagttc tcttagctga
     6301 ctgactagcg tttctccgta aaacactttc gtcaacgcat cttctacttg ataatcaagt
     6361 tccatacgca tccctcctct tcttattttt attttaccat tagtaagcaa attctagaaa
     6421 agataagagc aaagctcacc tcataacttg gaaataaata
//
LOCUS       DACBZK010000106         6286 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.112, whole genome shotgun sequence.
ACCESSION   DACBZK010000106 DACBZK010000000
VERSION     DACBZK010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6286
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.112"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..177
                     /locus_tag="IVD66_002539"
     CDS             <1..177
                     /locus_tag="IVD66_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146710.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLNLFNRIVGA"
     gene            190..690
                     /locus_tag="IVD66_002540"
     CDS             190..690
                     /locus_tag="IVD66_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAP6146711.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            787..2634
                     /locus_tag="IVD66_002541"
     CDS             787..2634
                     /locus_tag="IVD66_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HAP6146712.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2637..3533
                     /locus_tag="IVD66_002542"
     CDS             2637..3533
                     /locus_tag="IVD66_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6146713.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3583..3972
                     /locus_tag="IVD66_002543"
     CDS             3583..3972
                     /locus_tag="IVD66_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP6146714.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3959..>6286
                     /locus_tag="IVD66_002544"
     CDS             3959..>6286
                     /locus_tag="IVD66_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP6146715.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         2118 a          933 c         1348 g         1887 t
ORIGIN      
        1 caatctttag tcttactagc gattgtggtc attggtttgt ttttaggatt taaacgcgag
       61 ttttccaaac tgattggctt cttggtgatt gctttgattg cggtaggtct ggtctttaat
      121 gcttctggtg tgaaggatgt cttactcaat ttgtttaacc gaattgtcgg tgcctgaggg
      181 ggaatcacaa tggaacagat acgtgtttat attgcgaacc ttggaaaata caatgaaggt
      241 gagttggtgg gggcatggtt taccccaccc gtcgattttg atgaagtgaa agaacggatt
      301 ggattaaatg acgaatatga agagtacgca attcatgatt atgaactgcc ttttgagatt
      361 gatgagtata caccaattga ggaaattaat cggttgtgtg gtttagcgga agagcttaaa
      421 ggaacgccaa ttggtgaggt cgcttcagag attcaacatg ccttcttcaa ttctttcgag
      481 gaaatggtag agcatgtgga tgatatcatc tattatcccg attgtaatga catgagtgat
      541 gtagcgtatt acttgattgt agaagctggt gatttaggcg aagtaccaga acacttgaag
      601 acgtatattg attttgatgc gtgtggtcga gacttggaga ttggcgggaa ttatttggtt
      661 acgagtcgag gggtttttga actaatgtaa atcatttgtt agaattgacc agaaatttct
      721 atcgtacttt tacttttcta tttgatatac tgaaatagaa aatatttgtt gataggggtg
      781 ttactaatgg ttggcaataa gtggtacaaa tgtgatcttc atattcattc aactgcgagt
      841 cagtgctttc aggataaaaa ggttactgct aaggaatggg tagaagaatg tttaaacaaa
      901 ggactcgatt gtgttgcatt aactgatcac aatacagggg aaaatattga tgaatataag
      961 aaagtggcta tcgaaaatgg cttagatttt tttcctggag tggaattaac gtgtggagaa
     1021 aatggaactc atttactagt cctatttgat aaaagtgcat gtacaaatga tatctctgat
     1081 ttcttaacca agatgggtat aaaaagagag gattgggcca gcgctgcagc ttgctcaatg
     1141 aaatcagttt tagaagttat tgattttgct gagcacgagg gcttgctcgt tattcctgca
     1201 catatagatg agtttaatgg aatttcttca gcaaaatttg gaaatctagg aaagatattt
     1261 gaatcagaaa atatatatgc agtacagacg gttcaaaaag aattttttga aaatcgctca
     1321 caaatgattc cctcatctaa gcgtgacact atctatgata gtgtgaatgc cagatatgat
     1381 ggtagagttg gaaaagatac tttggaatct tggtataaat cagttgttga ggcagaaaaa
     1441 aataatatga catttcttag cttttctgat aacccacact cgaaaggaaa ttcaaaacat
     1501 ggactttggg gaataggcac aagatattcc tatataaaaa tgaaggacga acctgacttg
     1561 ggatcacttc gcgatgcttt aatgctaggc gaaactcgag ttcattctga tttttctaat
     1621 ttctccatta atgaaaatga agttttattg gaaaaattaa gcttttctgg gaccactctt
     1681 agcacaaaag aagttgtagt cgaattcagc gataatttaa cttcaattat tggaggaaga
     1741 ggaacaggca aatcttgtat tacaagattc ttggtctatg tccttggaaa ggaagcagaa
     1801 cttgatcaat tttctgaaat acaaagtgat tatcagaact ttgcacaaat tgaacataat
     1861 ggctctggaa tatttttgaa ggatacaatt gtgaaactga atattttcta taaggggaca
     1921 aaatatcaaa taataagaac acaggataga cattctattt atgaatttac acaagagaat
     1981 ggtctggttg aaaaagaaac agaacggttg agaatgattt ccgataaggt gagtatatac
     2041 tctcaaaaac aaatttatga aatttcaaaa aatcaaacta gtatactaga attactagat
     2101 ggatataact ctgatttgat ttcagagtat aaaaatgaga ttgaaacatg tgtaaacgaa
     2161 ataagaaaat taaattggga tattgtttct gtgaaaaaag aaatacaaga taaggcgaag
     2221 gtagagcttg aaattgaaga tttaaaaaaa caagtagaaa agctatctca taagagttat
     2281 aaagatgttt atgatgagta ttcaaaagag acagatattt atagggaact gaaacgtgat
     2341 gtggaggcac ttaaggaaat tcccaaaaat ctaactgata gtgttgacaa aattgacttt
     2401 ggcaatggta taaaagttac agacgaaatt gatgaacacc gcggagaatt gattaagaat
     2461 ttagtgacca atcgggctaa gattcaaaca ataattaatg aaatgtcaga tgaaattgat
     2521 agttatagag cagagctgaa taaatcagat tggaaagtta actataatga ggtttcaaag
     2581 aggtatcaaa gaggtatcaa aaacttagtg aagagttatc tcaagatgaa ttaaaaatgt
     2641 tacaaaacct tgattcttta tatcaatctt tatcaaaaac tgaagagcga ttggaagaaa
     2701 ttattcaaca agaaataaag cttaaagatt accaagttga ggttgactca gcaatgtcaa
     2761 gaatgaataa atcatatcaa aatctctatt ctgagagaag tagttcctcg cgcgaaattt
     2821 tttctgatat tacaggaata gaggctacta ttcaaccaaa tagggatttc aataattatg
     2881 ttaaagagct cagagcttgt attaataagg aggacacttt tgacagtgag tttggatctc
     2941 ttattgataa gctgacaaaa aattccatta ctaatcaaga tatatataat gacatacttg
     3001 atataagagt tagtggggaa agtagtattt tttcagataa aaaattaatc aattctataa
     3061 gaaaattgaa tgatgcacaa gttcttgaat tacaaaccct taagccaaat gatttagtag
     3121 ttatccgact tgaactaaat ggaaaaaaag ttagtttatc gaatgctagt gctggtcaaa
     3181 agacatctgc aattctttct atgattttgg cgtatggaaa ttcaccactc atattggatc
     3241 agcctgaaga tgatttggat agtcaattaa ttaataactt aatcgtaaga agtatcatta
     3301 caaaaaagga aaacagacaa attttaattg taactcataa tgcaaatatc ccagttaatg
     3361 gtgattcaga atggttgatt agcatgggag attcaaaaga aatatcggct gatcagtgcg
     3421 ggtcggtaga tgaacccaat atcaagccaa gaatatgtac tgtgatggaa ggtggcgagg
     3481 atgcttttac aaatagagcg aaacgctatg gttttaaaca aattgtagaa taacactaga
     3541 gggtgagaca tattattatg tccgcccttt ttaggaggaa aaatgaaaaa aataaaaagc
     3601 tataccagta tctgggcagt tgaaaaagtc atttacgcaa tcaatgattt tcagttgcct
     3661 tttcctgtga cttttaacca aatggcttgg ttcgttttat ctttactgtt tgtcatcgta
     3721 tttgcccatg tgcctccact atctatgata gaggaggtct ttttaaaata cttaggcata
     3781 ccggtggctg tcacttggtt tatgtcgcaa aagacgtttg atggcaagaa accactggga
     3841 tttttacgat cctttatcag ctatcacttg cgatttaagg tgacttttgc aggaaagaaa
     3901 gtcaaagaac agaagaaacg atgggatgaa cccagtactc ttgtaaggag tgtgaactat
     3961 gtatccgatt aagtatattg aaaataatct cgtctttaac caagaaggcg agtgttttgc
     4021 ctactatgaa ttagtgcctt acaattactc ctttttgtca cccgaacaga aatttcaagt
     4081 gcatgataac tttcgccaac taattgcgca aaatcgtgaa ggcaagatcc atgcgttaca
     4141 aattgccaca gaaagtagta ttcgcgccac acaagaacga tcaaaaaaag aaattaccgg
     4201 tagactcaaa gaagtagcga aacaacgaat tgatatacag acagaggcat tagtatccat
     4261 gattggcgat agtcagattg attatcgctt ttttattggc tttaaactaa ttgcgacaga
     4321 tgaagaagtc aatctaaaga gtctcaagaa atctttcttt tctgggcttc aagaatttgt
     4381 ctatggagtg aatcatcatt tgatgggcga ttttgtttcc ttatccaatg aagaaattcg
     4441 ctgctattct aagcttgaaa aattaatgga aagcaaattg gctcgaagat ttaaagtcag
     4501 gcgagtcaca ccgagtgacc tgacgtattt gattgaacat atttatggcg aaaaagggat
     4561 accgtttgaa gaatacgaat ttcagctacc aaagaaaaag ctaaaatcag aaacactggt
     4621 gaaacgttat gacttattac gtccaaatcg ttgtttaatt gaagaaaaac caaggtgctt
     4681 acggatggaa catgagaatc atgagtcgta cgtagcgtat ttaacaatta atacaattgt
     4741 gggggagatg gaatttcctt cctcagaact tttctattac cagcaacaac aatttacatt
     4801 cccaatcgac acaagtatga atgtagagat tgtgacgaat aaaaaggctt tagctaccgt
     4861 tcgtaataag aaaaaagaac tgaaagattt agacaatcat gcttaccaat ctgacaatga
     4921 aacgaattcc aatgtcttag atgctttgga ttccgtggat gaattggaaa ccaccttgga
     4981 tcagtcaaaa gaatctatgt acaaactgag ttatgtggtt cgagtgagtg ccgaatcagt
     5041 ggatgaacta aagcgacgct gtgatgaagt gctcgatttt tatgatgata ccaatgtaaa
     5101 actagtccgg ccctttggcg atatgatggg gctacatgaa gaattcttac cctcaagtaa
     5161 acgatatatg aacgactata ttcagtatgt tacgtctgat tttttggcgg ggcttggttt
     5221 tggggctact cagatgctag gagaattaga agggatttac tttggctaca atgtggatac
     5281 aggtcgtaat gtttacctga aaccggcatt ggcttcacaa ggagtcaagg gttcagtaac
     5341 caatgcgctg gccgccgctt tcctgggttc tcttggtgga ggtaaatcct ttagtaacaa
     5401 tctcttagtc tactatgctg ttttgttcgg tggtcaagct gtgattgtcg atccaaaagg
     5461 ggagcgagga gggtggaaag aaaccttgcc agaaattgcg gatgaaatca gtatcctcaa
     5521 cttgacgagt aagtcagaaa atcaaggtct gcttgatcct tatgtgatta tgaagaaaaa
     5581 gaaagactcg gaaagtttag caattgatat tctgactttt ttaacaggaa tttcaagtcg
     5641 agacggggag aagtttcctg tgttacgtaa agccattcga acggtgactc aaagtgatca
     5701 acgggggtta ttacaagtta ttaacgaatt gcgaaaagac gggtcaccaa tcgcggaaaa
     5761 tatcgccgat catatcgagt cctttaccga ttatgatttt gctcatttgc ttttctcaga
     5821 cggctcgatt acccaatcga ttagtttaga taaacagcta aatatcattc aagtggcgga
     5881 tttggtttta ccggatgcag aaacgacttt tgaagaatat accaccatgg aattgcttag
     5941 tgtttcgatg ctaatcgtca tttccacttt tgccttggac tttatccata gtaaccgaga
     6001 aatcttcaaa attgtcgatt tggatgaggc ttggagtttt cttcaagtgg ctcaaggaaa
     6061 aacgttatcg aataagcttg ttcgtgctgg tcgggccatg aatgctgggg tctatttcgt
     6121 cactcaaaat agcgacgatt tattagatga acgtttaaaa aataatatcg ggttgaagtt
     6181 tgcttttcgc agtaccgata ttcatgaaat caagaaaacc ttggaattct ttggtttgga
     6241 tcaggaggat caaagcaatc aaaaacgcct gcgagatttg gaaaac
//
LOCUS       DACBZK010000107         6213 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.113, whole genome shotgun sequence.
ACCESSION   DACBZK010000107 DACBZK010000000
VERSION     DACBZK010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.113"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            76..978
                     /locus_tag="IVD66_002545"
     CDS             76..978
                     /locus_tag="IVD66_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAP6146716.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            1011..1361
                     /locus_tag="IVD66_002546"
     CDS             1011..1361
                     /locus_tag="IVD66_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAP6146717.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            1395..2333
                     /locus_tag="IVD66_002547"
     CDS             1395..2333
                     /locus_tag="IVD66_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAP6146718.1"
                     /translation="MRYYFVDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPD
                     DIFVGTEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLI
                     TCIDRKTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAAR
                     KTTENEELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQ
                     RQTEKMIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTG
                     GLPGKSSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            2411..3304
                     /locus_tag="IVD66_002548"
     CDS             2411..3304
                     /locus_tag="IVD66_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP6146719.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            3342..3905
                     /gene="amaP"
                     /locus_tag="IVD66_002549"
     CDS             3342..3905
                     /gene="amaP"
                     /locus_tag="IVD66_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAP6146720.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            3920..4108
                     /locus_tag="IVD66_002550"
     CDS             3920..4108
                     /locus_tag="IVD66_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAP6146721.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            4121..5023
                     /locus_tag="IVD66_002551"
     CDS             4121..5023
                     /locus_tag="IVD66_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP6146722.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            5055..5297
                     /locus_tag="IVD66_002552"
     CDS             5055..5297
                     /locus_tag="IVD66_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP6146723.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(5553..5924)
                     /locus_tag="IVD66_002553"
     CDS             complement(5553..5924)
                     /locus_tag="IVD66_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146724.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         2244 a         1062 c         1242 g         1665 t
ORIGIN      
        1 tgaaagatca tccgtatacc aatttatact taaaaaaatt agcacacagt actctaacga
       61 aagtaggcga gatcaatgaa taaaaaagaa atagcagtag tcgcaagttg taacacaaaa
      121 ttcgtaccac atttagctgc attatttgtc tcagtattag ataattgcaa cccgtctaaa
      181 tttgttcggt tctatgtgat tgacgatgat atcgattttg aaagtaaaca gcttttacgc
      241 ttctcagtga aaaacgcacg aatgaactca gatgtggaat tcttgaaaat caataaagaa
      301 ttctttacaa atgtggtaat cagcgatcgt attccagaaa cagcttatta tcgtattgcg
      361 attccggaat tgttccgcgg cacagaagtt gaacgtatct tatatatgga ttgcgacatg
      421 atcgctttac aagatatctc taaattatgg cgtcttgact tcggtgattc aatcgtagca
      481 gctgttgaag acgctgggtt ccatcaacga ctggaaaaaa tgaaaatttc agctaaatca
      541 atgcgttatt tcaactcagg tttgatgctg atcaatgtga aaaaatggtt agatgaaaat
      601 attacgcaaa aagtattaga tttcatcgaa cataatccag aaaaattacg attccatgac
      661 caagatgcat taaatgctat cttacatgac cgttggttac cacttcatcc gcgttggaat
      721 gcacaaggct atatcatggc aaaagcaaaa aaacatccaa cagcagcagg tgaacgtgaa
      781 tacgaagaaa ctcgcaacaa tccttacatt atccattttt caggacatgt gaaaccgtgg
      841 agcaaggatt ttgaagggcc aacgaagaaa tattacgaaa aatatgcagg gatgacggct
      901 ttccgttgtg tagctaaatt ccctaaatat ccaaaatatg caaaagttca accaaaaaca
      961 gatgtagttg ttaaataata gaagacaaca actgaagagg gggagtagga atggaaatta
     1021 caatgtctaa aaatgcagta gagacgttaa ttgaaaaggt tggggaaaat acaaaaatcg
     1081 cactcgcgct tatcaatgat tccgatccat ttctaaggga caaaggtgct tttgcaaaag
     1141 gcagcttttt tcaaatcatt ccttttgttt cggaatttgg agaatatgcg actaaaatcg
     1201 agcatccatt attggacatc tatacatcta aattagagca aaattatttc ggtaaacgat
     1261 tgaacatgga cttcaacaaa cagcttgaca gcttttcatt agaaaatgaa atcgcagtac
     1321 tcgattataa tatcaaatta aagaactgct tcttcagcta atagtttcga gaaagtccaa
     1381 aaaggaggta tacattgaga tactactttg tggatgaaga aaagaatgta atagaaacag
     1441 atgaaaaaaa atataattgg ctcgtacttg atagtgcaaa gcccgaagag attgagcaag
     1501 caatcgaaga attcgagctt cctgatgata ttttcgtagg aaccgaatat ccggaagaag
     1561 tttctcggat ggagcgcctt tatgagacga aactagagca tccattttct ttggtagtga
     1621 ttaatctaga tcagtcagat aatcgtatcg aaaaaaaatt aacgccaata tcttttgtac
     1681 tttccgataa tctcttgatt acttgtatcg atagaaaaac cgaatttgtg gatcggctgc
     1741 tgacaaagca tggaaatcat ttaaactcgt ttgaaaagat catcacgtat acattattag
     1801 atatttacac ccattacgtg aaagaactaa gagagatgaa aaagcgaatt gacgctttgg
     1861 ataaagcagc tcgtaaaaca acggaaaatg aagaactgta taaacaggca gatcttgaaa
     1921 gagacatcgt atatatcgat cataccttaa gagatcaacg ggaaacaatg gatcaattat
     1981 ggaattctga aactttcatc aaacgtttag acgatgaaca gctactctat gatgtccatt
     2041 tgagacagcg acaaacagaa aaaatgatcg agatctatcg agatttatta gagagtattg
     2101 gtgatctatt caacgggatg atggacaata atctaaatca tatcatgaaa tatctagatt
     2161 cagctgcatt aatcatttcc gttccggcgt tgttcgcagg gatttgggga atgaatacag
     2221 gaggattacc gggtaaaagt tctgctctag gctttatact cgtagtcttt ggctctttga
     2281 tagcagcagt agttttaggt taccatttat accggaaaga ttatacaaat taaagaatct
     2341 atttaaaaca ggtatcaaac aaagaaattt gttttggcaa tacaatttaa aaactaggag
     2401 gaatacagca atgacagaac caaaattaat cgacccgcga aacttgtacc atacggagaa
     2461 atttcctaaa caagatcagg atacaccagc tttacagcag aatatgattc ctgttcctga
     2521 ttgtggagaa gaatcctatg aaggcaataa tcaactagaa aaccgccgtg tactaatcac
     2581 tggtggagat tcagggatcg gtcgtgcagc agcgattgca tttgctagag aaggggcaga
     2641 tatcgctctt caattcttcc caggagaaga aaaagatgca gaggaagtag caaaatacgt
     2701 gaaagttgca ggacgtaaga ttgtcttact accttttgat cttcgtgacg aacaagcacc
     2761 taaagaaatc atagataaag ccgtgagtga acttggcggg ctagatacga tggtactaaa
     2821 cgcaggacag caaatttctt gtcagtctat tgctgagtta ccacttgagc aagtcaaaga
     2881 cacatttatg ataaacatca tcgctatgtt tgctttagtg aaagaagctg ttccgcatat
     2941 cccagcagga ggagcaatcg taacaacaac ttctgttcaa gcattcaatc caagcgaaca
     3001 tttattagat tacgcagcaa caaaagcttc aatcgctaac tttacgatcg gtttagcaaa
     3061 acagcttgca cctaaaggaa tccgtgtaaa tggtgtagca cctggtccaa tctggacacc
     3121 attacaacta gacgaaggac aaccttctga ttcgatccct gaatttggtc agcaaagttt
     3181 actagaacgt gcaggtcagc caggagaatt agcaccagtt tatgttttct tagcatcgaa
     3241 taaagcaagt tatgttacag cccaaattta cggagtaact ggtggagaag cgatcaactt
     3301 ataagaagtt gatcgtttca cccctatgag gaggtgcgaa aatgaataaa ggtgtaaaaa
     3361 cgatcggagt gatcggaaca ttacttttgc tatctgtgct tttgtttgcg atactattaa
     3421 gtgcaaccta tccattgcct tttcagctag agaagtttcg attcttttcc atcactaatt
     3481 catacgtgca acaatatgta ttttggcttg ccgttgcatt tgctattttg acaattatca
     3541 cgttacttgt tttcctgttt tatccaaaaa caatcggaaa ctttctactg aaacatggtg
     3601 atggggagtt gacgttggat aaaaaagcaa ttgaaggaat ggttcgttct cacttgcatg
     3661 aagatgaatt catccattca ccaaaagtaa atgtcaaagc aacgaaaaac aagatcgccg
     3721 tcaatgtaaa aggggagttg aaacgaactt cagcactcat tggtaaaaca ggaacattga
     3781 tgaaagaaat cgaaaatgaa gtacaacaca tattgggaac aaaagagcca gtgaaagtat
     3841 cggtgaaata cacaggcttt gaagaaccag ctaaacgaag caatgaccgc aaacgagtag
     3901 aatagggggg ggaccaaaaa tgaaagaact attttcgaca tacaagctcc ctatcatctt
     3961 tggggtactt ggattgatat tagccgtttt atggatcacc gtgggctttt tcaagacctt
     4021 attgatcttg atcatggcag cgatcggcgt cgctatcggt ttttatctga aacaaacgaa
     4081 aatcttagat cactatttta aatcttagga ggaaacatcc atgaataaca ataacaaaaa
     4141 taataacaat aaaatgaaca accaaaaacc agtgtctgca catccagacc caacgacacc
     4201 aaaccaatca aatggtgtga acgatgaaaa gaacaaaaca gcaccagtat ctgcacatcc
     4261 agatccagta gtccctaacg ttcaacaagg agtagaagag aagaaacatg atgcagaaaa
     4321 gcatgcacct catcatccag gaactccaga atctaaagtt ccagaacaac atgatgcaat
     4381 cgatccttct aaacctgtgg aagagcaaaa acatccttct gaccatgcga aagcacaaga
     4441 aaaacttagt tctgaccaca caaacggaca aggaaaactt ggttctgatc atacaaataa
     4501 ccaaggaaag catgattctg aacaggaaga ttcaatgcgc ggtgagctga attatgaaga
     4561 taaagttgtg caaaaaatca tcggaatcgc aattgaacaa gtagacggtt tattatctgc
     4621 aaacggtggt ttcttctcta atgtggcagg aaaacttgtg aatacagata atgtaacggc
     4681 tgggatcgaa acagaagtcg gtaaaaaaca agtagcagtt gatatggatg tcattgtgga
     4741 atatggcaaa gatatcgaaa aaatctttga agaaatgcaa gaagtaatcg gcaaagaagt
     4801 aaaaaatatg acacatttag aagtgatcga agtcaacgct aacgtagtgg acatcaaaac
     4861 aaaagaagaa tttgaaaaag atcaagaaac ggtgcaagac aaagtaactg acgcagcgaa
     4921 aaaaaccggt gaatttgctt cgaatcaaac agataaagta aaatcagcag ctggaagcgg
     4981 cgcacaaaaa gtaaaagaaa atacagaacc acgggttcag taataaggaa gtaaaacatt
     5041 aggaggaacg aaacatggga tttatttggt cacttatcgt cggaggaatt atcggagcaa
     5101 ttgcaggagc aatcacgaat aaaggttctt cgatggggat tattgcaaat gtcgtagcag
     5161 gtttagttgg atcagcactt ggtcaagcat tattaggttc ttggggacca agtattgcag
     5221 gaatggcaat cgtgccatca ttgattggtg ccatcatttt agtactaatc gtatcattct
     5281 ttgctcgaaa actgtaaaaa gacttttaaa aagaggtcgt gaaaaagctg ttcttcatca
     5341 agtaataaga acagccaaac aaaaatagct tctcatattt ttcatttggt tgggcatatt
     5401 atcgaagatg caagcttttg aacactgttt atacggaata agaggctgtg acaagacttt
     5461 tgtcacagcc tcttatttat gcgggcaaat tcccaattag atttttaaaa gtttttcctt
     5521 aaatgtgtct ttattgatac agagaagctt ctttaataaa acaatgcctc cctaaatttt
     5581 cttgagatag gaaaggtgaa catacaaaat aatacgacca ctttgaaaac ccagatgatc
     5641 cacaaatgga tcgtatgata ctgatgaagt aaaaagcaat ggatcagaaa ctcaaagaga
     5701 ttgaaaaaga caaggaagaa ataatatctc ttttttactc ttgtctgttt tagccaataa
     5761 tagctcgtaa agtaatctag acaaacaaat agaagtaaac aaagtttcgt aagagcagca
     5821 atcgtatcat gttgctctgc tagacgattg acgagcagga aaaatgttgg taatggaata
     5881 tagatcacga gtaatgaaag aaaaaagtaa acaataaatg gcatactatt cctcctaatt
     5941 gtgtgagttc gccctcattt taaaataacg atatttgttt gtgaagcttt ttcgtgtcgt
     6001 aacaaatgtt atctaatgta tttttaaata aataatcatt attatcaaaa taatgtcaga
     6061 ctgtagacaa agtccatttt atggatgatg tctacagtct tttcttttat aatagattta
     6121 tgaaaacgaa tgcaaggagt gatagctatg atgtctaaaa acaatacgaa tggtagaaat
     6181 caatttgcga tgcttacgat tgatgatcta gtt
//
LOCUS       DACBZK010000108         6207 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.114, whole genome shotgun sequence.
ACCESSION   DACBZK010000108 DACBZK010000000
VERSION     DACBZK010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.114"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            191..709
                     /locus_tag="IVD66_002554"
     CDS             191..709
                     /locus_tag="IVD66_002554"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP6146725.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            837..1520
                     /locus_tag="IVD66_002555"
     CDS             837..1520
                     /locus_tag="IVD66_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HAP6146726.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1829..1902
                     /locus_tag="IVD66_002556"
     tRNA            1829..1902
                     /locus_tag="IVD66_002556"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1863..1865,aa:Arg,seq:tct)
     gene            2061..2420
                     /locus_tag="IVD66_002557"
     CDS             2061..2420
                     /locus_tag="IVD66_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HAP6146727.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2543..4174
                     /locus_tag="IVD66_002558"
     CDS             2543..4174
                     /locus_tag="IVD66_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HAP6146728.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4236..4877)
                     /locus_tag="IVD66_002559"
     CDS             complement(4236..4877)
                     /locus_tag="IVD66_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAP6146729.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVPPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            5159..5467
                     /gene="rplU"
                     /locus_tag="IVD66_002560"
     CDS             5159..5467
                     /gene="rplU"
                     /locus_tag="IVD66_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HAP6146730.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5494..5838
                     /locus_tag="IVD66_002561"
     CDS             5494..5838
                     /locus_tag="IVD66_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HAP6146731.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5851..6144
                     /gene="rpmA"
                     /locus_tag="IVD66_002562"
     CDS             5851..6144
                     /gene="rpmA"
                     /locus_tag="IVD66_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HAP6146732.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
BASE COUNT         1955 a         1023 c         1314 g         1915 t
ORIGIN      
        1 ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat aaaaaatgag
       61 ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca tttttacagc
      121 tataatttga aaaaaattta tcgttattat atgattaaga aggattgaat aaagaaagaa
      181 gttgaaaacg atacctgatt acaaaaaaat aacttttata agttctataa cgttgattat
      241 atttttaatt cttattcttc tcgtcgtctt ggttccccga atttttggtt tgactcctta
      301 tattattgag gacaaagaaa tgagtccata ttatgcacaa ggaaatctga tatatgtacg
      361 accgaaaaat acaaatgaga ttttagtcgg agatattatt acatattatg aaaattcagg
      421 aaaaaaaatc tcgacgcgtc gcgtaatagc cgttgaaaac aaccacgaag atttttatac
      481 aaaagctgat acaaagactt atattgagcc tggagtagta aaaaagagaa atattatcgg
      541 tagtcccatc tttcagattc catatattgg actagtcctt tcaaaaacgg catttgcatg
      601 gattcagggg ttattcttta cgattgcttt ttgcctaaca ggaatcacag catggaatac
      661 ctttgtagag ttgaaaaaga agcggagacg aacacagaaa tttttgtaag aatgttaaaa
      721 acataaatgt attccagaga tccaacgact cttctgaaca tgaaacacga gaaaacactc
      781 atgcagcttg tagatttagt cagttgttcg tataatgtgt gaagaggagg agtagtatgc
      841 gcaatgaaat gatgcatcgt cctgtagtca aagaagaact attggatttt atgcgtaccc
      901 agcaaaaaaa attaccgggt gagctaggca aactggaaga agaagctcat gtagcagaag
      961 taccagttat tccccatgaa acagttgtat ttttgaaatt tttacttgga cagcttcagc
     1021 ctgaacgaat cttggagatc ggagcagcta tcggtttttc atcaagtgtc atggccacga
     1081 caatcggaga aaacgctcat gttacgacaa ttgatcgttt cgatgtcatg atcgagaaag
     1141 ctaaaaaaaa ctatgaacgt ctaggactga cagataaagt gactttgctt gaaggtcaag
     1201 cagcagatat cttgccggag ttgtctggtc cgtatgactt tatttttatg gatagtgcaa
     1261 aatcaaaata tattgaattt ttacctgaat gcttacgttt gttaagaaaa ggtggcgttt
     1321 tgatggtaga tgacatcttc caaggaggaa cgatcttgct cccagatgaa gagattcccc
     1381 gtggcaaacg agctatccat cgtaaattaa atgaatttct tcgtgttgtg atggatcatc
     1441 ccgatttgac atcgacaatc ttgccattag gtgatggtgt gatcttaatg acaaaggaat
     1501 cagaaacaat cgagttgtga tacatgatta tggcagcctg tagataatcg attgaatcga
     1561 gggctcaatt cgaacttgat gtaaaagttt ctatatttgt aagtcaatta aaggatacag
     1621 gaaatctaaa taaacaggag tagcatgaag tcaatgtagc tcctgttttc aattgataac
     1681 cttagaacag ctgaaggaga atgtctcgtt ttaaaagatt gatttagtag ttgggccaaa
     1741 ataattcatt atttgctaat taaataacta tttcgtattg acagaagcaa tttaattatc
     1801 tataattatt gatgttccgc tgattcttgt catagtagct cagctggata gagcatccgc
     1861 cttctaagcg gacggtcggg ggttcgaatc cctcctgtga cgctaaaaaa ccgttagaaa
     1921 ctgaggtttc taacggtttt tctttgtttt ttgtgccaat attgtttgtt ttcaaaggca
     1981 aataaaataa aaaaacatcc ttatcgagta caattataag gagcaaaaaa ataaaactca
     2041 tcagaaaaga ggaagaagat atgacgatac tatctagaat tttagtgact ctagttgcaa
     2101 ttgaattttt ttatatcatg tatatcgaaa cggtgagaac tgattctgac acgacaagta
     2161 gggtttttaa aatgagtaaa gaagagttaa gcagaaaatc tgttcaaaca ttgtttaaga
     2221 accaaggagt gtacaatgga ctattaggag tgggactact ttatggagct tatctttctt
     2281 ccgcatctaa agaaatcaca agtatgctat taatatctat tttttttgtt gcattatatg
     2341 gcagtttgac tagcgatcgt tggattttac tcaaacaagg tgggctagct ctgttggcat
     2401 tgctttctat tttcttataa atatagaaaa aataagaatt tatctaacag gaaactttgt
     2461 gaaaaatatt actttatctc atgaaatatg atattctaat gaatggtatt ttagaaaatt
     2521 tcatgaaaaa ggagttagat aggtgttcaa aaattatgtt tcctcactaa aaaaagaatt
     2581 ttcaggttat gatctttcaa gatttcagaa agatcttttg gctgggatca cagtagctgc
     2641 tgtagcattg cctttagcct tggcttttgg ggtatcaagc ggagctgatg cggccgcagg
     2701 tttgattacg gctatcattg ccggtatcgt tattggcggt ttatcaggcg gtttttatca
     2761 aatatcaggt ccgacaggtg cgatggcagc tatcttgatg tctattgcgg caacaaaggg
     2821 aatgcaaggt gtattgcttg ctactttttt agcgggtcta tttttacttg cagcaggact
     2881 tttccgatta ggaacactga cttcttttat cccagcaccc gtaattacgg ggtttacttc
     2941 aggtattgct atcattattg cattaggtca gatcgataat ttatttggtg ttcactcgga
     3001 aggtacaaac gttattgaaa aactaagtag ttatcaaacg ataggatttc cgataaacac
     3061 agcctctttg atcatgggag ggctagtcat tttagggatg tttatctatc caaaaaaatg
     3121 ggcgaaacga atgcctagtt cgctgctggc tatcattttg gcaacagcag ttatgctatt
     3181 gttccattta ccagtagcaa ctgtgggtaa gattccacaa acattgatca gtagtaatcg
     3241 tttgaatatg ggagatttta gcttttctgc cttgcaacaa gtggcagttc cagctattag
     3301 cattgcttta ttaggaatga ttgaaagctt gctatgtggt gcttcggctg gccgaatggc
     3361 aaataagccc ttagatagca atcaagaatt aatggcgcaa ggaattggaa atctgttgct
     3421 tcctttcttt ggcgggattc ctgctactgc ggccatcgcc cgtacaagcg tggccatcaa
     3481 atctggtgca caaactagat tagctggtat gatacatgca gttgtcttac tgctctccat
     3541 gcttgttttt gcgccagtga tgtcacagat tccaatgcca gcacttgcag gtgttttgat
     3601 tgtgacggct tggcgtatga atgaatggga aacgatcaag gagctattta ctaataaata
     3661 ttggtcagca gttctattgt ttatccttac gatgatttgt acagttatct ttgatttaag
     3721 tattgctatc gtgatcgggg tgatcggcgg ctgtgtattt tttgttgtca aaagcgctgc
     3781 tatcacgatt tcattagaaa cgatcgattg gcaaagaatg gggctgccag aaacggaaaa
     3841 gctgaataac tggacagtag tgtatattag tggtccactg ttttttatgt cttcagaaaa
     3901 actcaaaaat aaattggaag aactaaatca tcacgatggt gtcattttct ccatgcgagg
     3961 cgtaccaagt attgatttga cggcacgtgc agtttttgat gaatttcaag aaaaagcaga
     4021 gcaaagagga caaacgatta tctatacttc cttgcagcca gaagtagaaa aacaactttc
     4081 tcacttgtgg gaacatacat tcacgcatca acatcaaaca gttgctcatg cgttgacagc
     4141 tttacatgcg aaatatactg caattagcca ttaaaacaat gaaaaagaac agacaagact
     4201 gtaaactgaa gattttatgg tcttgtctgt tctttttaat attgctgtaa aagtgaagct
     4261 agtacttgcc agtcttgatg gataacaggt acaagggagc gattgtagaa aatagctgct
     4321 ggatgaaaaa gtggaagaat tcgatagttt ttttctgacc attcgtaggc atccttttgt
     4381 tctgttaatt gtaagacagg ccctgtatag agttgaccat gatttttggt aaccgtatat
     4441 tctttgccaa gtaaacgttg aagaccaatg tttccaagtg tcgcaattaa ttttggcggg
     4501 accttcatca gttcgtaatc caatattggt gcatgcgcaa atacttcgga acgagtaggt
     4561 gtccgatttg gataaacagt ttctgactgt tgtgtccgtt tattgatccg atgagtcacg
     4621 cgatacgggc ggctccttac agcactggtg atatacacct cttctcgtgt taagccagtt
     4681 gaagaaagtg cctgcatcaa ttcttttcca gcttgaccgc taaaaggaac atgcgtatca
     4741 atctctgttt tccctggggc ttctcccacg agcatcagtt taggatgaag aggtccttgc
     4801 ccagcgataa atccttctac aggacggccg ttcattctta aagaagcttc ttgtatcagt
     4861 tcttttgggt attccattta tgctcctcct ttttctttta ttataagaat aaaagaaaca
     4921 caatgcgact attttatttg gtagaactgt gaggatagaa aagcagaagt attgcttgaa
     4981 tttttgtttt actttttgat tttaaattta gttgactaac ggttgctgtt ctggtaagct
     5041 agtactgttg taattgtgga ctccacagct acaaccgctc agaacaagta ataagcacag
     5101 catatgctgt cacttcggat ggcgagtcta agtatatcag aaggaggtgc tttatagcat
     5161 gtacgcaatt attaaaactg gtggtaaaca agtaaaagtt gaagtgggac aagcaatcta
     5221 tgttgaaaaa cttgacgttg aagcaggaga aaaagttgtt tttgacgaag ttatcttagt
     5281 aggcggagaa tctacaaaag taggcgctcc aactgttgca ggtgcaactg ttgaaggtac
     5341 tgttgaaaaa cacggcaaac aaaagaaagt cgttactttc aaatacaaac ctaaaaaaca
     5401 ttcacaccgt aaacaaggtc atcgtcaacc atatacaaaa gtggttatcg acgcgatcaa
     5461 cgcttaatag cgtttgagaa agaaggccta tatatgatca aaggaacatt taagcgaaat
     5521 gacgcaggtc agatcgtttc attcactttg accgggcatg ctgatgctgg tccttatgga
     5581 agtgatatcg tttgtgcggg tgtttctgcg ttagcgatca gcactgtcaa cgggattgcc
     5641 tcattagccg gttttgagcc gattgttgaa atgaatgaag aagaaggcgg ttatctttat
     5701 accgaagtca cttcaggaat gacacaagaa caaaacaata ttgctgagat tctattagaa
     5761 aatcttttat taggattaca atcgatagaa gctgaaaact cagaatatat ccaaattaaa
     5821 acaattaatg ataaatagga ggtgcagacc atgttgttat ctatgaatct acaattattt
     5881 gcccacaaaa aaggtggcgg ttctacatct aacggccgtg actcagaatc aaaacgtcta
     5941 ggtgctaaac gtgctgatgg acaaacagtt acaggtggat caattcttta ccgtcaacgc
     6001 ggtacaaaaa tctatccagg tgtaaacgtg ggtatcggtg gagacgacac tttatttgca
     6061 aaagttgatg gcgtagtacg tttcgaacgt aaaggccgta acaaaaaaca agtgtctgtt
     6121 tatccagtag ctcaagaagc ttaattgaat cttatgatta aagaggttgt gacaagactt
     6181 ttgtcacagc cttttttgtt tataaaa
//
LOCUS       DACBZK010000109         6184 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.115, whole genome shotgun sequence.
ACCESSION   DACBZK010000109 DACBZK010000000
VERSION     DACBZK010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6184
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.115"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(41..1021)
                     /locus_tag="IVD66_002563"
     CDS             complement(41..1021)
                     /locus_tag="IVD66_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP6146733.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(1045..2529)
                     /gene="galT"
                     /locus_tag="IVD66_002564"
     CDS             complement(1045..2529)
                     /gene="galT"
                     /locus_tag="IVD66_002564"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HAP6146734.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(2541..3530)
                     /gene="galE"
                     /locus_tag="IVD66_002565"
     CDS             complement(2541..3530)
                     /gene="galE"
                     /locus_tag="IVD66_002565"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HAP6146735.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            3778..3945
                     /locus_tag="IVD66_002566"
     CDS             3778..3945
                     /locus_tag="IVD66_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HAP6146736.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(4007..5818)
                     /locus_tag="IVD66_002567"
     CDS             complement(4007..5818)
                     /locus_tag="IVD66_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HAP6146737.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(5815..6180)
                     /locus_tag="IVD66_002568"
     CDS             complement(5815..6180)
                     /locus_tag="IVD66_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HAP6146738.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
BASE COUNT         1691 a         1309 c         1109 g         2075 t
ORIGIN      
        1 gctgcggtat cactccattt tcccacagct tttccatctt ttatttcgtt gattctcgaa
       61 taatcaactc tgtttccaca ataatctttc ttgaaaccgg tgctttggaa ttacttaatt
      121 gaagaatcgt ctccactgct agctctccca tccattcggt ataaactttt acagtagaaa
      181 gcgagggcgt tacatatttc gctacactga catcattgaa gcccatcaca gaaatatctt
      241 ctggtaccac taaacctttt tcttgaatcg ctttcagtgc gccaatcgct aatgcatcat
      301 tagctgcaaa aagcgcatca ggaacatgcg gattcgtttt taaatactgc ttcactgctt
      361 gatatcctga ctcgacagaa aaatctgctt cgataattgg accttcgtcg tagccttttt
      421 ctgccaaaac ttgttgaaat gccataattc tgggatcttt tagccgctga tggtttttct
      481 tcgtatattc tgttccagca agcatagcga tatgttgcgc tttatgggag acaaagtgtt
      541 caatgacttt ttgaacactt gacttaaagt cgacaactag agagtcgatt ccttgagaag
      601 tgccgtcaga atctaccaaa agcaaggcat tttgggatcc tttcatttct aataactgag
      661 cttcgtcgaa ttttcctagt gcgatcgttc catctgccgg aagatcacta atggaatccc
      721 acgtttcttt caataaagta acgtttgctt cttctgcctt tttttcgatt cctaggcgaa
      781 tagataaata ataaagatct tcaagctctt ccgtatcgtc gtaccactgg atcaggcgaa
      841 gcgtttgctt agtatttgct gcatttttac gatgtttcgt ataatttaag cgttctgctg
      901 cttcaaaaat tttttgcttt gtggctaagc caacggaaag atcaggatca tagttgagaa
      961 ctcttgaaac agtagcagga gaaactcctg ccaactgcgc aatgtcttta attgttgcca
     1021 tttgtctctc ctcctttttt acgtttataa aatcgcagta aatcgttcaa acgctgcctg
     1081 tcctttttca tctcgcttga atactccagc gtcttccagt acacgtgcaa aaacctgacc
     1141 tacagatttt tgtacgacat cggtgaccgt atctttcgtc aaatcaggat gttctttttt
     1201 taattgttct gcccacggac gatgatattc agccatctgg ttttcttctc ctaataagaa
     1261 atgctctact tctactagtt ctggtttcaa acgaggtggt aaaacagcaa gccccattac
     1321 ttcgatcaac ccaatgttct cctttttgat atgttggaca tctttatgtg gatgaaaaat
     1381 cccatcagga tgttcttctg aaacattgtt gtctcgaagg acaaggtcca actcaaagta
     1441 attgtccctt cttcgtgcaa ttggcgtaat cgtatggtgt ggtgtaccat ctgctgaaaa
     1501 agctctgata gatactgttt catccgaata tgctttccat ttttccaata ctgagttagc
     1561 tgcttcaata agcaagtttt tctctgttga ttgcaaacgg atcacagaca tcggccattt
     1621 cacgactcct gcgatgactt gcggataatc ttctagtttg ataagttttt ctatcggtgc
     1681 ttttgccata ggaaattcat gacgtcctgc ctgataatga tcatgagaaa gaatcgatcc
     1741 tccaacaatt ggtaagtcag cattcgaacc aacaaagtaa tgaggcaaga cttcagtaat
     1801 ccgaagcagt ctagcaaatg tttcctttgt gattttcatc gggcggtgtt gttctgataa
     1861 aatgatcgaa tgttcattgt aataagcata aggggaatat tggaatcccc agctttcacc
     1921 gtctagattc attcgaataa tccggtgatt ggtgcgggct ggatagttca agcgacctct
     1981 atatccttcg ttttccatgc aaagcatgca ggtaggatag tctactttta ccgcctcgcg
     2041 ttctgctgcg atttgttttg gatctttttc tggcttagat aaattgattg tgatttccag
     2101 ttcaccatac tccgactctg ccggaaattt gatgtttttt gcgatggctc ttgttttgat
     2161 gtagtcattt ttcttactta aattaaagaa atactcagtt gcttcctctg ggcttttcga
     2221 atagtgctgt gcaaagaatg cattgacgac tgaaggtggc ggtgtgagaa aatccattaa
     2281 ttgcgcttca aaaatctctt gttctgctgg caattctgaa agaacaccat tttctcttgc
     2341 cttagcgaca agctgatcca ataagtctac agattcttcc ttaactggtc ttacttcaat
     2401 gctttctaga gcatcttctc ctaccatccc taaaagacga ttctgtaaat ataagcggtc
     2461 catttccatc catccgccag cttcgatcgc aagtgtggca aaatcacaaa tcgtttgact
     2521 gattgacata tctcattccc ctattcttca taaccatttg gatggctgac atgccaatcc
     2581 catgctgttt tgataatcgc tttgatatct gtgtattcag gtttccagcc cagaatctct
     2641 ctcgcttttt cacttgaagc gactaatcgg ctaggatctc cagctcttct tggtgctatt
     2701 tctgctggaa tttcttttcc tgtcacttct ctagctgctt ctagcatttc cttgactgag
     2761 tatcctttgc tgctgcctaa attgaagaag ttgctttcat ttccttcttt caagtattcc
     2821 aaagctaaaa tatgtgcagc aatcaaatct tctacttgaa cataatctct gatacatgtt
     2881 ccatctggtg tatcataatc gtctccataa acagccaagg cttttctttg accaagagct
     2941 acttgtaaaa tgattgggac aagatgcgtt tctggtgtat gatcttctcc gatagatgca
     3001 tctgcttttg ctccggctac attgaagtag cgcaaagcga catagcgcat gccatatgct
     3061 tggtcacacc acttcatcat tttttccatc atcaatttac tttcaccata cggattttta
     3121 ggattagctg gtgtatcttc tgtgattgga gactctttcg gctctccata agttgctgca
     3181 gtagaagaga atacgatttt attcacgttg aactcgtgca tgacttcaag taagatttgc
     3241 ataccgtata cgttgttgtt gaaatacatc aatggttttt cgacagattc tcctactaaa
     3301 gagcttgcag caaaatggat tactccttca atcggttcct tttcaaatac ggaacgtaga
     3361 aattctttat cccggatgtc tccttcataa aaatgagcat ctggatgtac tgcttgtttg
     3421 tgacctgtga gcaaattatc taccacagct acttgatacc ccttttgaac tagctggtct
     3481 acagcgtgcg aaccgatata accggctccg cctagtacta aaattgtcat aaaaaacact
     3541 cctttgatta gtaaaattgt gtttgttgat tctatataat ttaaaaaacg aagtttactt
     3601 ttatggtgaa aacaaacaaa gtaaaatttc gtaaattcat atggtaaatt tataataaaa
     3661 catttagtaa acattttcaa ggattttttg caaaggttta caaacaaacg taaaactagc
     3721 ctttttttct cttttgttcc ataatagata taacaaataa taaatgaggt ggattcaatg
     3781 aaaaaatttg tatctggaat attagtagga agtctggcaa cagccgctgc cgttgctggt
     3841 ttggttgctt ctgtgaaaaa aacagtgatc gatccaattg acgaaaaaga agcaatgatc
     3901 gaagaaaacc gtaaaaaagc aatgcgtaaa cgcgtttctc gttaataatt atttaaaaat
     3961 acgcatgaag actttctaaa aaacagataa gtcatcatgc gtatttttat ttgtcagtca
     4021 atataagttg tgctatttta tctgcctgtc tcagattcca tggatctgta taaggtctag
     4081 ctactgctgc agttagccaa tccacacctt caacaggtat tccatagcaa taaaagtcag
     4141 actggatttc ccctgaagca tcaatcacgc gattcgtacc tcgctcaaca tctatagctt
     4201 ctgaatgata acttcctgta ttatctgaaa atgaaaaagg gcgaacaagt ttgttttcct
     4261 tcaaattttt tatgacagga ttacttgaac gagaaaagct tgtttgtggc aatcgagctt
     4321 caatcaaata gcgactgctg atttctttat cttgtagaga aataacatag cggttgtgct
     4381 tttgctgaat atcaaatggc ggttcgatca aatgaaaaat acccgcatct atcagtgctg
     4441 ctaattcttt cgtccgaatg attggcggac cgatcgttaa aaagctattt agatgagtaa
     4501 accatcccca tagtatttct ttgtattcct tagcagaaaa aacgtgccat tcaatagcct
     4561 gccggattgg atcacgccag tcttttaatg catcaaatgt tgaagcaaat gctcctgtgc
     4621 aattgccttt ttccgcttct tttatctgcc cttcaataaa tattcggcta gcttctgaaa
     4681 agggctcatt ctgataggca agaggagttt ctaaatacga ccaatcccat ctataaggga
     4741 ttagtgctgg atgctttccg agacactcct ctgaagagag ggagagaaaa tcatgctcaa
     4801 aatttttctt tggaatcggc aagtgatatt cttcgatgat tttcttgtaa taaaacaact
     4861 caacgtcttt tttcagatag tcaaaaaatg tttcgccagt caaaaatccc gactgatgcc
     4921 attgctccag gttttctttt gttagtaacc gtggccatgc cattgctccg ccttgctttt
     4981 gatttcttcc tcgagggtaa taagggagcc cccttcttga tccactgtat acaatcggtt
     5041 ccttgcctga tggatgatag accagttttc ccttttcgtt ctcgaagcgc cctcctcttg
     5101 atactgtaaa caatccgaca taatcaaaaa aacttaagcc tagacctctt aaaaagacat
     5161 tttctttagg cggtatcttc gaaagatcta catctgcagg attagaagga agctgataca
     5221 gtaaaacatt tttctttgcg tagtctaccc acactctttc ttcttctgtc tcatcatttt
     5281 cccagtgacc gcttgctaaa acaagctgat cgatagaata gctttgctga tctgtctgta
     5341 aaagataacc atcttttctt ttgcttactt tttttactaa agaataaaca aactgaatag
     5401 aagctggaaa ttcttcttgc aactttgaga aaaaccagcg ttgatagagt ccgtataaac
     5461 atcgagtaga ttgctgatct ttttccagac gattgatttc ttctataatt agttgcttat
     5521 ttttggttac cgtctgttcg atataatctg tagcaggtcc tttactccat tgaaacaagt
     5581 tgggtccctg tgttaccaat cctccactgg acaatgtttc atctgtaaaa agcgtcactt
     5641 gttgagaaac agaattcatt aataactccg gtggctgatt caaccgccaa actcgacctc
     5701 caggaccatt gggatcgaaa agaaaaagtt caagagaatg tctgtcctga ttattatgga
     5761 gaatcctttc tgctacactt aatcctctag gtccggcacc aatgatccct attttcattt
     5821 gcatgcctcc atttcgataa attttttcaa taaaacagca tggttctgat gttcattttt
     5881 tgcaccataa acaaaagtaa tgactggatg ttctttcata agttgactga gtttaaaaat
     5941 agcttgcttc ttttcttctt cgaaaatcaa ttcttgctgg tatttctttg caaatgaagc
     6001 aaatcgttct ggtacatggt caaaagtttt gcgtgcttca ttactaggtg caatttcttt
     6061 caaccacaga tctaactgcg ctttttcttt tgaaattcct cgtggccaga atctatccac
     6121 gagtattcta tagccatcct ctttttcagc atcaaggtaa acacgtttta atttgatcat
     6181 agtt
//
LOCUS       DACBZK010000110         6159 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.116, whole genome shotgun sequence.
ACCESSION   DACBZK010000110 DACBZK010000000
VERSION     DACBZK010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6159
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.116"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..532)
                     /locus_tag="IVD66_002569"
     CDS             complement(<1..532)
                     /locus_tag="IVD66_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAP6146739.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(553..1497)
                     /locus_tag="IVD66_002570"
     CDS             complement(553..1497)
                     /locus_tag="IVD66_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAP6146740.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     FTFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKIN
                     GDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRLLKQYRTKGFA
                     YFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEDQNKALALADKQKEYEEPATTINEKIKQKKRELELL
                     QQIKQLEKEKKALEKQTESALSEKEKKSLLSDLDNLFQ"
     gene            2134..2220
                     /locus_tag="IVD66_002571"
     CDS             2134..2220
                     /locus_tag="IVD66_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAP6146741.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(2341..3030)
                     /locus_tag="IVD66_002572"
     CDS             complement(2341..3030)
                     /locus_tag="IVD66_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146742.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(3037..3315)
                     /locus_tag="IVD66_002573"
     CDS             complement(3037..3315)
                     /locus_tag="IVD66_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146743.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(3275..4189)
                     /locus_tag="IVD66_002574"
     CDS             complement(3275..4189)
                     /locus_tag="IVD66_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP6146744.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(4171..4551)
                     /locus_tag="IVD66_002575"
     CDS             complement(4171..4551)
                     /locus_tag="IVD66_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAP6146745.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(5001..5288)
                     /locus_tag="IVD66_002576"
     CDS             complement(5001..5288)
                     /locus_tag="IVD66_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP6146746.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(5308..5532)
                     /locus_tag="IVD66_002577"
     CDS             complement(5308..5532)
                     /locus_tag="IVD66_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HAP6146747.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
BASE COUNT         1632 a         1147 c         1040 g         2340 t
ORIGIN      
        1 atttccatag ctgccaccat tttttccaat tctttgtttg ttcgtccatt gtttctgttg
       61 cttcagaaag agtcgttgaa ctattctctg aagactcttc cgtataagtc aactgcagtt
      121 gctcctgaag tttttcgatt tgttggttgg cttgcagggt gagttgttgt tgctggtcga
      181 gtagtttttg tatatgagaa ttattttgct ctttgagggc aagttgttct cgtaaaaatt
      241 cattttcttc acgcaactga tctagcaact tgtttgcaac cacgtttttg tttggtatat
      301 aagcattttt atcgttgttt tgttcatgtt tatgcaactt atctagcaac ctttgattgt
      361 ctaagttgcg agcaagttgc aatactccag aacgcaatac aaccttataa ccacgctcat
      421 ttttagctat catggaagaa tctaattttt ggatatgttt cgatattgct tgcctactca
      481 tcttaaaaag atctgacaat tcctttattg taaaggtttc ttgtggttgc atactggttg
      541 cctcctaggt tgctactgga ataaattatc taaatcagat aataaacttt ttttctcttt
      601 ttccgaaagt gcggactctg tttgtttttc aagagctttt ttctcttttt ctagttgttt
      661 gatttgttgg aggagttcaa gttctcgttt cttctgtttg attttttcgt taattgttgt
      721 agcgggttct tcgtattctt tttgtttatc agctaaagcc aatgctttat tttggtcttc
      781 tttggttggt gcatgtttgt taaagtcgtc tgcttttttg atctcaggtt tgaacgtaaa
      841 ttgatagcca ataacaggtt ttccccgtcc ttttccgtat ttctttttga ttgttagtcc
      901 tttgaagatt gcagttagtt cttgacgtat aggttttata actcgtttat ctatatcagg
      961 ttgcttataa cttttaggaa tatctaataa ttcaagaaag tcttctttgg agaaatatgc
     1021 gaaacctttg gttctgtatt gctttaacag acgaaacata gtctttgcat agccactttg
     1081 tagctcgttg aattgttgta aagaatagcg tacccactcg tctaaattat ttaacaaagg
     1141 cagtgctttt tcgtaaattc gtatatctac gtaaggattt tctacgtccc cgttgatttt
     1201 aaattctgta aacattacaa acatatcgta agaaagccca gactcacttc tacgaccaaa
     1261 gcgtaaagat aagatttttt cataagttgc ttttaaatct tctacaaatc gtacatttgc
     1321 agttgctttg tagttactta aatcttttag ttggtcaaac gtaaaacgaa ctgtcttatc
     1381 ccctttttca cgcattctag acacgatgga aaaaaacaaa ttcatttcaa ccggtgtaaa
     1441 ttttcttaaa ggaattgtat ttaattcatg gtggtatttt acaatctcat tagccatata
     1501 atcacctcaa tccaattatg aatgacattt tttaaatgtc aagacattca tatttgacgt
     1561 tcaaacagac aaaatgtcct tcataaacag acaaaatgtc cttcataaac agacaaaatg
     1621 tccttcataa acagacaaaa tgtccttcat aacattctgt atccattggt agagtaagga
     1681 cacagcttac ggtaaagagg tttaaaaaga ggtttaaaaa gagatataaa aagagggggg
     1741 ctaattttcc cgcctaaaaa ccacttcttt tttctttaaa caggttcgcg catttttcaa
     1801 aactgccaat ccaaaacctt gcttcctacg gtcgccaaaa aggtgtgatc gctacgctct
     1861 cacattgtac tgcgcagtcg cctaaaggct cctttgctaa aaacatgttg gtaaagaggc
     1921 ctttgagcgg ttctgaatgc ttatctaagc cgttttaaga cagtcttgga taaaaatcct
     1981 tatctagctt taaagcgcct tacaggcggt cagggcaagc cctaacaacc ctaaaataag
     2041 cgatacttaa aaacaccaca caagtttaat tttttaagat ataataactt gtcgcctatc
     2101 cgacagtctt gcgactggaa ggaggtgtat ctaatgtttg aattgttcat ttgccccctt
     2161 cttatagaag tttgtgtctc tttattcagt tattggttga ataaccgaaa caagaagtaa
     2221 aatcaataaa ggcgacatca acctgaaaaa aagccccaga gaatccgacc tctctggggc
     2281 tttcgtgtat ctaatgtttg atcatttgca tgtttagttt aacatgattg ccgatcaaat
     2341 tcaattttgc tgttgctgat ctaaccattc cttgacactt tttagataat ttaatgccgt
     2401 ttcttttttc gttggatttt gtatgttcgt tgcttgctga agcagtgctt tataacgttc
     2461 gtaggtaact gattgttgcc gttcttttcg ttcctgttca ctagttgaaa aagggattgt
     2521 atcactgaat aaattataac aagcttcttc tgtctgcgta tctttaaaat attgcacgtc
     2581 ttttttggtt cgctcatagt tgtcttgaac ctctttttgc tgtttttctg gcaagttttg
     2641 ataaagacga gtgagttttt ccatgttttt atccgtcaaa cgtttttctt gattcacaaa
     2701 aatatcgttc atttcctcat aacaagtggt aaactcttcc attttttgtg ttaacacttg
     2761 ctcctttttc tttttatcac atgctgcttc atacttttga gtgatatccc ctaataaaat
     2821 acttcttgaa atacgtttat ttccctctaa aacgccgaat aaaccactta aaacgattga
     2881 taatgtaaat ataacccctg gcaataaaaa cctcttaaat cgaattttag agccttttaa
     2941 tgaatatctt gtttgataag ccttatagct aagccaaata attcctaaaa tactggcaaa
     3001 aatgagtaga tagggtaaat agaatgccat ttctatttat tctccccata ccagccaaaa
     3061 ggctaacagt gtcatgatta agcaacataa gggggcaaga atatccattg atcgctgcat
     3121 aattactttt ttctgttctt tatttcgctg gtttaatagc gcatggtgga attttttgac
     3181 ttgtgaatca attgtagttt gtattctttc tttggtataa ggtgcaagaa aagcacgttg
     3241 tttctttatt tcattttcta tgtcttgtaa cgttttagaa cgataattct tgttggtagt
     3301 ctgctcctct ttcaacgtgt tggtcatggt ttcttcgagt cggtctaatt tccggttgtt
     3361 cagtcgtaag agttcgttgt tctcttcgta cttcttttgc agtttcgcga atgctagctc
     3421 gagctcttcg tagctcgttg gttcgttgtt gattgtaggc tcgttctcgt ctgtccagct
     3481 catgtaaaat cgtctccttt tcgtaatcct ttcctagttt gttggatcgt acttttttct
     3541 ttttgtggat caattcgtaa gtaaaatttt tcccacgatt caagcaatga atgccgaatg
     3601 ttttaagaga atcacaaaat tggttatacg ttcgagtttt tttgtttttc attgtttgat
     3661 caatcgcaaa ccgaatttcg tctttccaaa caggttcatt tttttctttt aatttgattt
     3721 cagacatggt tcgtttttcg ggtttcttcc ctcgttcagt gattgttaag tcatgttcaa
     3781 gacaaatctc gtcatttagg tcataacatt tgtttaaaaa tgcttgacca tgggcttgaa
     3841 atttgttccc agtttccaga ttgacggagt taatgacaat gtggttatga atatggtctt
     3901 tgtctgtatg tgtgtaaatc gcgatttggt ggtcaggggc tatttttttc gcatactctg
     3961 cccctagttg attggctttt tcagcggtaa tttctcctgg tcgaaaagac tggatcaata
     4021 agtgtgcttg tacacgatcg tcttttccat acagcatgcg aatttgtttc atttcgcttt
     4081 tggcataatc aatgtcacag tttatccctg ttttgacggt tgctcgtggt tcggcgtaat
     4141 tgatcgctcg gctacaagaa gtggttcggc ttactttaac tgttgccata tcttttgtag
     4201 ctccttttgc atgattttta ggttttcgga taagcgttgg gcgtcgccag gatcaacgtc
     4261 gtgttggtgt gtgttgcacc acttggcaat ttgattgata ttcccgccag ctttggctaa
     4321 atcgcgcgcg attgcctgag caatgtctgg cgccactttc ggtgtcacca gacgcgcgtt
     4381 ttgtgccttg gctttcacga aagccggcac actcatttgc aaagcttcag ctgactgctt
     4441 cagctttgca aattcggatt cgctcactcg aaaactgatt tgttttggct cggatcgata
     4501 ggtatatttt ttagaatgat tgctagccaa atattgattt tgttcgctca taagtcccac
     4561 cctttcagta cgtcctacgg acgtatcgtt cgcaatacca ttgtacctaa aaaggtacaa
     4621 taagtaaagc tcactaaagc tcactaaagg gcttggcaag ctctatattt gctagccaaa
     4681 tacctacgta tttggtgcaa ataaccgctt gtcaaagggg cgcaagctcc cccttgaatc
     4741 cccctccccc ccactctcca caatacaaaa aagactagca aatgctagcc actttttgta
     4801 aagtttcgct tgtttcacct tcggtgaaat tgttgcaaat caataattag gtagagctac
     4861 atttttttcg ttgttcaaag attcttatgc catttactat taataaatct ataaatatga
     4921 taatttttcg gctctataat ttatgggact gatgaatcag aattgattct tcagtcccat
     4981 tttcatttta ttccaaagaa ttaactccaa ataccaatag aagcccatcc tctatatact
     5041 tgagattcct tactaacaat ttcttgtaat tctattaaag atttaggtaa tccaaattta
     5101 tgttttaaaa tatatcttcc aagaaaacta cttaatttca tactaacttc accaacactt
     5161 tttccctcac tgatttcttt agaataaaga aagagctttt cttttaagtc aggatagtca
     5221 tctatagttg cttcattgta tactttacta attgcattta aaagtttttc ttctttagta
     5281 aaatccatta taataacctc cctaccacta ccttctaggt gcccatggac catgattaac
     5341 ccaaccatta acaataattt ttccaatttc tcctttagct tgattccaat ctacccaaca
     5401 tttttctttg ttacaataaa gaccatttcc atagtaagta gctgcatcaa cttttattcc
     5461 tgtaccgatg ccagctagac aagttcctaa tattcctaga ataacacaat gttttaatac
     5521 tttctttttc atgattgttt ttccttttcg tttttttaaa attgcttgtt atattaaata
     5581 atcttagtaa ttttattata taacatttta ttatataaca atgattaacg tcataaaaag
     5641 tagttttgaa ttcataatcg tttaaattaa attataaaat cgttatatta agatctagta
     5701 gacataatgt acatactacc aagtaacgcc tgtaccaagg gatccaggcg ctgattttgt
     5761 gaatttttat tggtctaggt taaaagctct ttttaaggct tggttttctg cggttgtttc
     5821 tttctaattc tttgtgaata ttgatcggtc attttttaaa tacttgttat ttttgtttgt
     5881 gtttgttatg ctttttacat atctcatatt catttattat tcttttctaa ggttaataat
     5941 aggataatct ctttcagaaa gactgctcgt acgagcagtc ttttcttatt tatcaagttt
     6001 ttctacaaat acttcctcat tttgactgtt gtagtaatta ggattgagtt ttagttcccc
     6061 ttttttattt cctttgttgg ccactgataa taacattggg ctaaagctta atattcctag
     6121 taggatagaa ccgaatagca agtgtttttt tgtcataag
//
LOCUS       DACBZK010000111         6082 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.117, whole genome shotgun sequence.
ACCESSION   DACBZK010000111 DACBZK010000000
VERSION     DACBZK010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6082
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.117"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..752
                     /locus_tag="IVD66_002578"
     CDS             <1..752
                     /locus_tag="IVD66_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAP6146748.1"
                     /translation="LEMTYDKLMDLRFGKRSANGLDIDRFVMFSEFKIRGTAKDPYVD
                     IQVYEKALPLLNNLDEWVRYSLQQFNELQSSYAKTMFRLLKQYRTKGFAYFSKEDFHE
                     LLDIPKSYWNNQANVDNRVIKPIRQELTAIFKGLSIKKKYGKGRGKPVVGYQFTFKPE
                     IKKADDFNKHAPTKEEQNKALALADKQKEYEEPATTINEKIKQKKRELELLQQIKQLE
                     KEKEALEKQTESALSKKEKKSLLSDLDNLFQ"
     gene            773..1306
                     /locus_tag="IVD66_002579"
     CDS             773..1306
                     /locus_tag="IVD66_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAP6146749.1"
                     /translation="MQPQETFTIKELSELFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLGNQMLLDRLHEYEQDNDKNVNIPSKNVVTNKLLDQLREENEFLRE
                     QLALREQNNSHIQKLLDQQQQLTLQANKQIEKLQEKLQLTYTEEAPENDSTTLSEATE
                     TIDKQIDTEKKWWQLWK"
     gene            1942..2475
                     /locus_tag="IVD66_002580"
     CDS             1942..2475
                     /locus_tag="IVD66_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146750.1"
                     /translation="MKKFTLGVALLTIGAVVLPSTTIVYASENSQVVSLNENNATENV
                     VIEYTEDGMVVTKYEDGYSAEDFANSSDIMTRAAVARWGKKEYTNIAVTTGVAANAIN
                     AAFWAGGKASTSMFGIPGWAIGALLTGASWTKKGASPGNAVAKEWDKNGNGWIGFYYQ
                     RGYDAAGRVVATRYSTL"
     gene            2487..2690
                     /locus_tag="IVD66_002581"
     CDS             2487..2690
                     /locus_tag="IVD66_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146751.1"
                     /translation="MFLISKSLKSLKTFTKKNPQIATIRIFIFAIAVAIIVNMLSGGQ
                     LYKSGLFLVLILVVLDIIKSKKK"
     gene            3012..3392
                     /locus_tag="IVD66_002582"
     CDS             3012..3392
                     /locus_tag="IVD66_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAP6146752.1"
                     /translation="MSEQHQNLASDHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPD
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            3374..4288
                     /locus_tag="IVD66_002583"
     CDS             3374..4288
                     /locus_tag="IVD66_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP6146753.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     TLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPNHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKTEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYTQFCDSLKTFGIHCLNRGKNFTYELVHKKK
                     KVRSNKLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTFTP
                     EQSEIRPTRRNHEQHVERGTDHQQELSL"
     gene            4533..5222
                     /locus_tag="IVD66_002584"
     CDS             4533..5222
                     /locus_tag="IVD66_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146754.1"
                     /translation="MAFYLPYLLISASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLV
                     GVIFALSIVLSGLFGVLEGNKRVSRSILLGDITQKYEAACDKKKKEQALAQKMEEFTA
                     CYEDMNNIFVDQEKRLTDKNMKKLTRFYQNLPEKQQKEVQEKYEQVKKDVQYFKDTQT
                     EEACCNLFSDTIPFSTSEQERKERQQSVTYERYETLLQQATNIQNPTKKETALNYLES
                     VKEWLDQQQQN"
     gene            complement(5343..5429)
                     /locus_tag="IVD66_002585"
     CDS             complement(5343..5429)
                     /locus_tag="IVD66_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAP6146755.1"
                     /translation="MFERFICPLLVEVCVSLFSYWLNNRNKK"
BASE COUNT         2243 a         1066 c         1136 g         1637 t
ORIGIN      
        1 atttagaaat gacttatgat aaattaatgg atttacgttt tggtaaaaga agtgctaatg
       61 ggctcgatat agatagattc gttatgttta gtgagtttaa aatacgtgga actgctaaag
      121 atccatatgt agacatacaa gtttacgaaa aagctttacc tttactaaac aatttagatg
      181 agtgggttcg ctattcactc caacaattta acgaattaca aagtagctat gcaaagacta
      241 tgtttcgatt actaaaacaa tatcgaacta aaggttttgc ttatttttct aaagaggatt
      301 ttcatgaact attagatatt ccaaaaagtt actggaacaa ccaagcaaac gttgataatc
      361 gtgttataaa gcctatacga caggaattaa ccgcaatctt caaaggatta tcaatcaaaa
      421 agaaatacgg aaaagggcga ggaaaacctg tcgttggcta tcaatttacg tttaaaccag
      481 aaatcaaaaa agcagatgat tttaataaac atgcaccaac caaagaagaa caaaataaag
      541 cattggcttt agctgataaa caaaaagaat acgaagaacc tgctacaaca attaacgaaa
      601 aaatcaaaca gaagaaacga gaacttgaac tcctccaaca aatcaaacaa ctagaaaaag
      661 agaaagaagc tcttgaaaaa caaacagagt ccgcactttc gaaaaaagag aaaaaaagtt
      721 tattatctga tttagataat ttattccagt agcaacctag gaggcaacca gtatgcaacc
      781 acaagaaacc tttacaataa aggaattgtc agaacttttt aagatgagta ggcaagcaat
      841 atcgaaacat atccaaaaat tagattcttc catgatagct aaaaatgagc gtggttataa
      901 ggttgtattg cgttctggag tattgcaact tgctcgcaac ttaggcaacc aaatgttgct
      961 agataggttg cacgagtacg aacaagacaa cgataaaaat gttaatatac caagcaaaaa
     1021 cgtggttaca aacaagttgc tagatcagtt gcgtgaagaa aatgaatttt tacgagaaca
     1081 acttgccctc agagagcaaa ataattctca tatacaaaaa ctactcgacc agcaacaaca
     1141 actcacccta caagccaaca aacaaatcga aaaactgcaa gaaaaactac agttgactta
     1201 tacagaagaa gctccagaga atgactcaac gactctttct gaagcaacag aaacaataga
     1261 caaacaaatt gatactgaaa aaaaatggtg gcaactttgg aaataactgg agggaacatt
     1321 catgacaaga aaaaatcttc tattcggttc tattttacta ggaattctag gattcagtcc
     1381 gatgttattg tcagtgatca ataaagggaa taaacatggt gaattgaaat tgaatccaaa
     1441 ttattacaac agtcctaacg aagaattgtt tgtaaaagaa acagataaat aataaaaaag
     1501 actgctcttt cgagcagcca gttaaaaaat aatgagtgtt tattcttgaa aaagcaacgc
     1561 gcttatgaag cgctaccaaa aatttatcat attttattaa aaataacaac ccagtaaaaa
     1621 atgactggta aaaattcaca aagaaacgga aagaagcaac cgcagaaaat caagcttaaa
     1681 aagagctttt gacctagacc aatcgaaaat cacaaagtga gcctctgtat cggttgatac
     1741 aagggctact tggcatagtg tacattatgt caacaagaat ttaatataac atattttcct
     1801 aatgcattct aactatacca cattatcaaa aatataaatt atctttacta aataaaatat
     1861 tgacaagcct ataccttttg ttttatgatt ttcacaaaga aaacgttttc tatatatttt
     1921 tctgtatcag gaggaaattc tatgaaaaaa tttactttag gggtagcttt gttaactatt
     1981 ggggcagttg ttttaccgtc aactactata gtttatgctt cagaaaattc ccaagtggta
     2041 tcattaaacg aaaacaatgc tactgaaaat gtagttattg agtacactga agatggtatg
     2101 gtcgtaacta aatatgagga tggttatagt gcggaagatt ttgcaaattc ttcagatatc
     2161 atgacaagag ctgcagttgc aagatggggc aaaaaggaat atacaaatat tgctgtaacc
     2221 actggagtag ctgctaatgc tattaatgct gccttttggg caggagggaa agctagcact
     2281 tctatgtttg gtatcccagg ttgggcaatt ggtgctttgt taacaggtgc aagttggact
     2341 aaaaaaggtg cttctccagg gaatgcagtt gcaaaagaat gggacaaaaa tggtaatggc
     2401 tggattggat tttattacca aaggggatat gatgcagctg gaagagttgt agctactaga
     2461 tattcaacgt tataagttaa ggagtgatgt ttttgatatc taaatcatta aaatcattaa
     2521 aaacatttac taaaaagaat ccgcaaatag ctactattcg tatttttata tttgctatag
     2581 ctgttgctat aattgttaat atgctaagcg gagggcaatt atacaaatct ggtttatttt
     2641 tagtgttaat cttagttgtc ttagacataa taaagtctaa aaaaaaataa atcgatacat
     2701 tttagaagaa tagggttgtt tgaatattac aaagcaacaa tttcaccttc ggtgaaataa
     2761 gcgaaacttt acaaaaagtg gctagcaaat gctagccttt ttttgtattg tggagcgtgg
     2821 attttgaggg ggattcaagg gggagcttgc gctcctttga caagcggtta tttgcaccaa
     2881 atacggaggt atttggctag caaatataga gcttgccaaa cccttttagt gagctttact
     2941 cattgtacct ttttaggtac aatggtattg cgaacgatac gtccgtagga cgtactgaaa
     3001 gggtgggact tatgagcgaa caacatcaaa atttggctag cgatcattct aaaaaatata
     3061 cctatcgatc cgagccaaaa caaatcagtt ttcgagtgag cgaatccgaa tttgcaaagc
     3121 tgaagcagtc agctgaagct ttgcaaatga gtgtgccggc tttcgtgaaa gccaaggcac
     3181 aaaacgcgcg tctggtgaca ccgaaagtgg cgccagacat tgcccaggca atcgcgcgcg
     3241 atttagccaa agctggaggg aatatcaatc aaattgccaa gtggtgcaat acacaccaac
     3301 acgacgttgc tcctgatgat gctcaacgtt tatccgaaaa cctaaaaatc atgcaaaagg
     3361 agctacaaaa gatatggcaa cagttaaagt aagtcgaacc acttcatgta gccgagcaat
     3421 caattacgca gaaccacgag caaccgtcaa aacaggaata aactgtgaca ttgattatgc
     3481 caaaagtgaa atgaaacaaa tacgcacgct ttatggaaaa gacgatcgtg tacaagcaca
     3541 cttattgatt cagtcctttc gaccaggaga aattaccgct gaaaaagcca atcaactagg
     3601 ggcagagtat gcgaaaaaaa tagcccctaa ccaccaaatc gcgatttaca cacatacaga
     3661 caaagaccat attcataatc acattgtcat taactccgtt aatcttgaaa ctgggaaaaa
     3721 atttcaagcc catgggcaag catttttaaa caaatgttat gacctaaatg acgagatttg
     3781 tcttgaacat gacttaacaa tcacggaacg aggaaagaaa accgaaaaac gaaccatgtc
     3841 tgaaattaaa ttaaaagaaa aaaatgaacc ggtttggaaa gacgaaattc ggtttgcgat
     3901 tgatcaaaca atgaaaaaca aaaaaactcg aacgtatacc caattttgtg attcacttaa
     3961 aacattcggc attcattgct tgaatcgcgg aaaaaatttt acttacgaat tggtccacaa
     4021 aaagaaaaaa gtacgatcca acaaactagg aaaggattac gaaaaggaga cgattttaca
     4081 tgagctggac agacgagaac gaacctacaa tcaacaacga accaacgagc tacgaagagc
     4141 tcgagctagc attcgcgaaa ctgcagaaga agtacgaaga gaacaacgaa cttttacgcc
     4201 tgaacaatcg gaaattagac cgactcgaag aaaccatgaa caacacgttg aacgaggaac
     4261 agaccaccaa caagaattat cgctctaaaa cgttaaaaga catcgaaaac gaaataaaga
     4321 gacaacgtgc ctttcttgcg ccttataccc aagaaaggat acaaactacg atggattcac
     4381 aagtcaaaaa actccaccaa gcgctattag accagcgaaa ccaagaacaa aaaaaggctt
     4441 taattcaacg atcgatggat attcttgccc ccttatgttg cttagtacta acattattag
     4501 ccttttggtt ggtatgggga gaataaacag acatggcatt ctatttaccc tatctactca
     4561 tttctgccag tattttagga attatttggc ttagctataa ggcttatcaa acaagatatt
     4621 cattaaaagg ctctaaaatt cgatttaagc gatttttatt ggtcggggtt atatttgcct
     4681 tatcaatcgt tttaagtggt ttattcggcg ttttagaggg taataaacgt gtttcaagaa
     4741 gcattttatt aggggatatc actcaaaagt atgaagcagc atgtgataaa aagaaaaaag
     4801 agcaagcatt agcacaaaaa atggaggaat ttaccgcttg ttatgaggac atgaacaata
     4861 tttttgtgga tcaagagaaa cgtttaacag ataaaaacat gaaaaaactc actcgttttt
     4921 atcaaaactt accagaaaaa cagcaaaaag aggtacaaga aaaatatgag caagtaaaaa
     4981 aagacgtgca atattttaaa gatacgcaga cagaagaagc ttgttgtaac ttatttagcg
     5041 atacaatccc tttttcaacc agtgaacaag aacgaaaaga acggcaacaa tcggtcacat
     5101 acgaacgtta tgaaacactg cttcagcaag caacaaacat acaaaatcca acgaaaaaag
     5161 aaacggcatt aaattatcta gaaagtgtca aggaatggtt ggatcagcaa caacaaaatt
     5221 gaatttgatt agcaatcatg ttaaactgaa cctgcaaatg atcaaacatt agatacacga
     5281 aagccccaga gaggtcggat tctctggggc tttttttcag gttgatgtcg cctttattga
     5341 ttttacttct tgtttcggtt attcaaccaa taactgaata aagagacaca aacttctaca
     5401 agaagggggc aaatgaaccg ttcaaacatt agatacacct ccttccagtc gcaagactgt
     5461 cggataggcg acaagttatt ataccttaca aaataaaatc tgtgtggtgt ttttaagtat
     5521 cccttatttt cgggttgtta gggcttgccc tgaccgcctg taaggcgctt taagaacaag
     5581 ataaggtttt ttacccaaga ctgtcttaaa acgacttaga cgagctatca gaggcttccc
     5641 ccacctccgt tactgacttg tttttagcaa aggagccttt aggcgactgc gcagtacaat
     5701 gtgagagcat agcgatcaca cttttttagc gaccgtaggg agcaaggttt tgaattggca
     5761 gttttgaaaa atgcgcgaac ctgttggtag aaaaaagaag tggtttttag gcgggaaatt
     5821 ttgtcaccct cttttataat ctctttttaa accttttttt aaacctcttt accgtcggct
     5881 gtgtccttac tccttcaatg gatacagcgt tttataaact acattttgtc tgcttttaaa
     5941 ctacattttg tctgctttta aactacattt tgtctgcttt taaactacat tttgtctgct
     6001 tttaaactct ttttttgcac tcacgtatgt tataatatgc attatcacag acaaaacgtt
     6061 gtttataacg tctgtatcca tt
//
LOCUS       DACBZK010000112         5993 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.118, whole genome shotgun sequence.
ACCESSION   DACBZK010000112 DACBZK010000000
VERSION     DACBZK010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5993
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.118"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..365)
                     /locus_tag="IVD66_002586"
     CDS             complement(<1..365)
                     /locus_tag="IVD66_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAP6146756.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHK"
     gene            complement(369..497)
                     /locus_tag="IVD66_002587"
     CDS             complement(369..497)
                     /locus_tag="IVD66_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAP6146757.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            complement(490..1581)
                     /gene="phnW"
                     /locus_tag="IVD66_002588"
     CDS             complement(490..1581)
                     /gene="phnW"
                     /locus_tag="IVD66_002588"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HAP6146758.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            complement(1798..2277)
                     /locus_tag="IVD66_002589"
     CDS             complement(1798..2277)
                     /locus_tag="IVD66_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HAP6146759.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            2636..3418
                     /gene="rpsB"
                     /locus_tag="IVD66_002590"
     CDS             2636..3418
                     /gene="rpsB"
                     /locus_tag="IVD66_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HAP6146760.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3517..4398
                     /locus_tag="IVD66_002591"
     CDS             3517..4398
                     /locus_tag="IVD66_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HAP6146761.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            4534..5256
                     /locus_tag="IVD66_002592"
     CDS             4534..5256
                     /locus_tag="IVD66_002592"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010761216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HAP6146762.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            5259..5816
                     /gene="frr"
                     /locus_tag="IVD66_002593"
     CDS             5259..5816
                     /gene="frr"
                     /locus_tag="IVD66_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HAP6146763.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
BASE COUNT         2033 a         1090 c         1222 g         1648 t
ORIGIN      
        1 tttttatgga tcatataagg aaacggtcga ccataccctt cgacgtcttc aaaagttgcc
       61 atgaagtctg gtgaatacct ttcttttttt gcggtttctg ctacgattgt catcatagga
      121 gcattaaatc cattcgtgga accaatattg atcccagcgt ttctcaaccg ttcgatcgtt
      181 tccaatgtgt cgggtttcaa ggtagaatgc ttgaccaaat ctttaaacag ataatgttca
      241 aattgttgat acaattcctc cacctctttt tcctgaggta gttgtccata aatagctatc
      301 cattgttttt tgacagaagg gagggaaaga agctgttgga tatgatccca ttttaatttt
      361 cccatcggtt agcggatttc tttgtcagtc agttggattc ctttttctag aaaagcattt
      421 ctaaaagcgt ggacaggagc catacagcca aagtccacag ttgttcctgc ccaatcaaaa
      481 attacagttt taatcattaa cgttctcctt atagtctttg ataattgctg tcagttccaa
      541 aatatcttcc ggatagatct cgccaatatt tccgatacga aaacattcat gatcgctgat
      601 tttcccggga tagatcacaa atccattttg ctttaaatac tgataaaaat gattaaaatc
      661 aaatcgccag tccttagggt aaagaaaaga ggtgatgaat ggcccctgat attcttgaat
      721 gaaaggctgg aaccccatct ctgtcatttt ttgtcgtagc acatgattat tggcgagata
      781 acgtgaatat cgagtttcga ttcctccttc tgcctctagt tccttcagcg cttgttgaaa
      841 agccaaaacc gtatgggtag gggaagtgaa acgccatttg ccattctcgt tttccatcac
      901 gcggtactgg tcatatagat caagtgacaa acttcggcta acattttttc gtttttccag
      961 ttccgcttta ttagcaagta caaaagaaaa gcctggaaca ccttgaatac atttgtttga
     1021 gctggaaatc aaaaaatcaa tccctagttc ggctacacaa atcggtatcc caccaaagct
     1081 tgacatcgcg tccactataa acaaaagatc tctttcttgt gtgacagcag caatctcttc
     1141 caaattattc aaaataccgg aagtagtctc gctatggacc attgctagtg cggagataga
     1201 cggattctct tcaatcagct gtgtaatcac atgagcttgg aggatttgat gttccgatac
     1261 ctcataaacg gtatagttca gtttcagaca ttcgcacatg ttgatcattc gttgtctata
     1321 tgcgccgttt gaacaaatca gtacagtatc ttctggcctg atcacagaac ttaataccga
     1381 ttctaccccg aaggagctgc taccttgcat taagaccgtt gtgtatattc cttccgatac
     1441 ttgagcaaga tccaataatt tttttcttat ccattgtgta atttctttgt attcttgatc
     1501 ccaagtacaa tgatcgatca gcatagcatt tttcactgtt tcagaagtcg tcaatggtcc
     1561 agaagttaat aatttataca tatgatttcc tttcatttct tttttgaaat acacaaagag
     1621 caagaagctg ctcttgttaa catccaatat aaatgatgat tattgtgatt caatcaaggt
     1681 gttgaaaaat ttgaataaaa aatgatgtat ttttgtaaag agtgtaaagg tttattcaat
     1741 aaggaaaata ttgaaaataa aaaaacacgc attccatatt aggaatacgt gctctgatta
     1801 aaaaagtgat acttcagttg gatggtgaag aaattcttct actcgttttg cgtcctcctc
     1861 attttccgag atgaccatga tcgtatcgaa tccagcaatt gtactgacaa tagagggagg
     1921 tttgatctca tctaaaacag atgcaaataa atgagcattg tctggcaagg tattgacgat
     1981 cgtcaaaaag tggactcgtt cgactttcaa tacaatgtct tcaatcattt gaaccagccg
     2041 atcctcttcc tcagtcctag tctcaggagt tcctttttcg cgaaacaata cgaagcggga
     2101 aacgccattt tcatcaggtg ccttcacgat ttttagatca cggatatctc gagaaatcgt
     2161 tgcctgcgtg gcggtaacgc cataatgccc aagtttgttt aatagttctt cttgcgtacg
     2221 gatcgggaat tcttcaatga cttgtttaat cagcaaatgt ctttgagctt tgcgcatttt
     2281 ctttctcctt tacgaaagat ttcacatgta tcataacaaa aaaaagaagg attgcccaat
     2341 aatattcgtc ttttatacct aaaattattt tatggaaaaa ggataataaa gaaacaaaga
     2401 gaaatctact gtttttcttg aattcttttt atctttcagg taaactattg aatgttgagc
     2461 agaaaagtat atttgctctt gcgatacgga tcttttgtct gtataatagc tgagggtgct
     2521 ttatgcatca gcaaatccac attcttattg gattgtcggt aggtgcttga aaaagtttgc
     2581 cggcaaggta gaagataaga agaggaaaaa taaaaccaaa tcggaggaaa caaacatggc
     2641 agtaatttct atgaaacaat tactagaagc cggcgtacac tttggtcacc aaactcgtcg
     2701 ctggaatcca aaaatgaaga aatatatctt cacagaaaga aacggaatct acatcattga
     2761 cttgcaaaaa acagttaaat tagtagatgc agcttatgat tacatgaaga gcgttgctga
     2821 agaaggcggc gtagcattat tcgtaggtac aaaaaaacaa gcacaagaag caatcaaaga
     2881 agaagcaact cgtgcaggac aatacttcgt taaccatcgt tggttaggcg gaacattgac
     2941 aaactgggat actatccaaa aacgtatcag ccgtttgaaa caaatcaatg caatggaaga
     3001 agatggaact tttgaagttc tacctaaaaa agaagttgct ggtttgaaca aagaacgtga
     3061 acgtcttgaa aaattcttag gcggtatcgc tgatatgcca agaatcccag atgtaatgta
     3121 catcgttgac ccacgtaaag aacgtattgc tgttcaagaa gcacacaaat taaatatccc
     3181 aatcgtagct atggttgata caaactgcga tccagatgaa atcgacgtag taatcccttc
     3241 aaacgacgat gcaattcgtg ccgttaaatt gattacttca aaaatggctg atgctttcat
     3301 cgaaggaaac caaggtgaag atcaagtagt tgaagaagat ttcacagaag aaaacacagc
     3361 aacatcaatc gaagaaatcg tagatgttgt tgaaggcgac aattcttcag cagaataatt
     3421 ttgaatgatg gagctgtttc aaaggctggg cgacaagcct cactctcctt tgaagcagct
     3481 ttttttaaaa agaaaaacac acaggaggag ttaaacatgg cagacgttac agctaaaatg
     3541 gtaaaagaac tacgcgaaat gactggcgta ggaatgatgg atgcgaaaaa agcattagtt
     3601 gaagtagaag gcgacatgga aaaagcagtt gatcttttac gtgaaaaagg aatggcaaag
     3661 gctgcgaaga aaaatgaccg cattgcagct gaaggattgg cttcagttgc tgtgaaaggt
     3721 aacactgcag caatcgttga agtaaactca gaaacagact ttgtttctaa aaacgaaatg
     3781 ttccaagatt tagtaaaaga aattgcagaa cttgttgctg aaaacaaacc agcagacatg
     3841 gaagctgcaa tgaaaatcaa aacagataaa ggtacaattg aatctgactt gatcgaagca
     3901 actcaagtta tcggagaaaa aatcagcttc cgtcgctttg aagttgtaga aaaagacgac
     3961 aatgctgcat ttggtggata cttgcatatg ggcggacgta ttgccgtatt gactgttcta
     4021 gatggaacaa ctgacgaaac agttgcaaga gacgtagcta tgcacgtagc agctatcaat
     4081 cctcgttatg taaacgaatc acaaattcca gaagctgaat tagaacatga aaaaactgtt
     4141 cttacagaac aagcattgaa cgaaggcaaa ccagcgaata tcgttgaaaa aatggtagaa
     4201 ggacgcttga agaaattcaa agcagaaatc gctttggtgg accaaccatt cgttaaagat
     4261 cctgatatga ctgttgaaaa atacgttgca tcaaaaggcg caactgttaa aacattcgta
     4321 cgtttcgaag ttggcgaagg tatcgaaaaa cgcgaagata actttgtaga agaagttatg
     4381 agccaagtga aaaaataatt ctgttgaata acagacggga acgcacggtt tgtgcgctcc
     4441 ctttttttaa gcaaaacaag aaaaaccagt cttagagtgt cgaaatcatc taagtatggt
     4501 aaaatggcaa tagaaaatat tggaggaatg aacatggtca caccgaaata tcagcgtgta
     4561 gtcttaaaat tgagtggaga agctttagct ggggacgcag gatttggaat caaaccacca
     4621 gtaatcaaag aaatcatcca agaaatcaaa gaagttcacg agctgggcgt tgaaatggca
     4681 atcgttgtgg gcggcggaaa tatctggcgc ggacaaatcg gagcacaaat gggcatggaa
     4741 cgtgctcaag ctgattacat gggtatgtta gctacagtta tgaatgcctt agctttacag
     4801 gatacgttgg aaaacgtggg tgtaccgaca cgcgtgcaaa cttcgattga aatgcgtcaa
     4861 atcgcagagc catatattcg ccgtaaagca gaacgtcatt tagaaaaagg acggatcgtt
     4921 atctttgcag gcggtaccgg caacccgtac ttctcgacag acacaacagc agcattacgc
     4981 gcggcagaaa tcggcgcaga tgttatcctg atggctaaaa acaatgtaga cggtgtttat
     5041 tctgctgatc cgaaagtaga tgcaaatgca gtaaaatttg aagaactgac tcatctggaa
     5101 gttattgcca aaggattaca agtcatggat tcaactgcaa gttcactaag catggataat
     5161 gatattccac tgcttgtctt caatttaaat gaacacggaa atattcgccg tgcaatctta
     5221 ggcgaaaata tcggaacaac tgtaaggggg aaataaaaat ggcagatgca attatgacag
     5281 aagcaaaaga aaaaatgaaa aaagcagcac aaaatcttca acgtgaactt gggcaaatcc
     5341 gcgcaggccg tgcgaacgct agccttttgg accgtattac tgtgaactac tacggtgcgc
     5401 caacaccatt gaaccaaatg gcatcaatcc aaattccaga agcacgtgtt ttaatgatca
     5461 caccttttga caagagcatt cttcaagatg ttgaaaaagc tattatggca agtgatatcg
     5521 gaatcagtcc aaccaatgat ggaaatgtca ttcgcttagt tatcccgcaa ctgacagaag
     5581 aacgcagaaa agaattagct aaagatgtga aaaaagaagc agaaaatgca aaaatcgcga
     5641 ttcgtaacat ccgtcgtgat gcgatcgatg aatataaaaa acaacaaaaa aatggtgata
     5701 ttaccgaaga tgatttgcgc ggattagaaa aagacgtaca aacattgaca gataacagca
     5761 tcaaagaagt agataagatc gctgctgata aagaaaaaga attattggaa gtttaataaa
     5821 atcataaaaa cagaggggcg gatcattccg cttcctctgt ttttatttat atttctttta
     5881 tttaaaaatt aaaaaaagaa aaaattattc agtttttaaa taaaaaaaca atgatttcat
     5941 aggaaaaaca gttagatatt gctataatac ttaagatagt gggaatcttt taa
//
LOCUS       DACBZK010000113         5976 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.119, whole genome shotgun sequence.
ACCESSION   DACBZK010000113 DACBZK010000000
VERSION     DACBZK010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5976
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.119"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            147..584
                     /locus_tag="IVD66_002594"
     CDS             147..584
                     /locus_tag="IVD66_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146764.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            679..1563
                     /locus_tag="IVD66_002595"
     CDS             679..1563
                     /locus_tag="IVD66_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAP6146765.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            1787..4954
                     /locus_tag="IVD66_002596"
     CDS             1787..4954
                     /locus_tag="IVD66_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146766.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            4974..5519
                     /locus_tag="IVD66_002597"
     CDS             4974..5519
                     /locus_tag="IVD66_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HAP6146767.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            5547..>5976
                     /locus_tag="IVD66_002598"
     CDS             5547..>5976
                     /locus_tag="IVD66_002598"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HAP6146768.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFI"
BASE COUNT         2006 a         1013 c         1315 g         1642 t
ORIGIN      
        1 aaatcaacag tagtttaatt actacttgat ttagttcttt ttattttaaa aatttttttt
       61 acttagaatc cagcgaccct agatattttt ctgtataatc ttaaataaag aaaacaatat
      121 caaaaaatgc acgtagaagt agataaatgg agtggttttg caaatttctt ttatttctag
      181 aagttattca cgtatacgga tttgtttttc tcacaaataa aaaggcagga agtacaatgg
      241 atcatttgta tataaaatat attcatcaat tttccgtttt ggtgttaggc acactaatta
      301 tagcggggat tgtcgcattt attattcaag gccgtgacat attaacagta catcaagagt
      361 ttttcagtta tgcatttggt attcctctga tcgctataag gtctgataac aaaaagtgga
      421 agaaacgcta ttacattctc ttgctatttt tgtgttttta tctgccacct aagattttta
      481 ctttattagg tatacaatgc ctatcatttt cttttatttc ctatatcatt gttttaattt
      541 tcctcagttt catagtatgg atgttttatc ttgtcaaaaa ataaatgaat gtttcatgaa
      601 cagtacttca tcacagccta atttttttct ttatgctatc gttatattaa agaaatcaat
      661 cagaagggaa agaaagtgat gaaaaaagtt ttattagtgg taaaccccag ttcaggcggt
      721 gaacaagcaa aggaatttga gcaattagcg atagcaaaat tggaatcggt gtttgatgaa
      781 gtggtcgtct tgcatacaaa aaaagcaggg gatgcaaaaa actttactcg cgaagcggct
      841 acggaagggt atcatagtgt gtttgtcatg ggcggagatg gaacagtcaa cgaaggaatc
      901 agtggaatcg ctgaacaaga acatcggcca aatttcggat ttttcccatt gggtacggtg
      961 aatgacttgg ctcgagcatt agggataccg ctagaacctg aggaagcgat caatcatttt
     1021 tcgattgaat cagtcaagcc attggatatt ggaaaaataa atgacgacta ttttatgaat
     1081 gtcgtcgcaa ttggctctat ccctgaatca atcaatgatg tagatgcgga gaagaagacg
     1141 aaatttggaa aactagctta tttcatgtca ggaatcaaac agttagcttc cacacaatcc
     1201 tactcgtttc acgtagaagt tgatggaaag aaggaagaaa ttgagagcag taccttgctg
     1261 ataggactaa ctaactcagt cggcggtttt gaaacattac ttccaaatgc aaaagtggat
     1321 gatggtaagc tccatttggt ttatttaaaa gattcttctt tgatcgatac gcttaaaaca
     1381 ttgccagacc tattaaaagg agtagatgaa tctacgaaaa atctagccta ccttacttgt
     1441 gagcaattag ttgtgtcatt agctgatgag gaagaattga cgacgaatgt tgatggagat
     1501 gaaggggata aattacctgt gacaatcaaa gtattgccct cacatttaca ggtttattgt
     1561 taaaatggag gttgtgaccg aggagttggc gggagaacac cgcttgttcg ggataaggga
     1621 ctgtgacaag acttttgtca cagccttttt tttgtacaaa aaagaaattt acacctaata
     1681 gaaaaatttt tccataaaaa tacatatttt aaatatgaaa gtacaattgg aaatagatta
     1741 aaacgataaa ataaaattgt caaaacgtca gagaggatgg tggagaatga atcaatgtgt
     1801 aaaaaagctg attgcgtcga ttttgtttgt cttccctctc ttgatggtga catccgtttt
     1861 tgccgatgta gagaaaacaa acgaatcaac gcaatcagag aatcaaagtt ttgacaagac
     1921 tactttttca gaagaatcga ttacttctga aactacagaa tctcaaagtg aggcttctac
     1981 taataaaagg caagaagaaa ataagacaag tgagacctca gaagtagctg aacaaacgtc
     2041 tgatagcagt gaagcggcac tggcaagagc tgtttcagcg gatgggtaca gcgaagctgc
     2101 cacaacagaa gaactggcgc agcttctcgc agacgaatca gtaactaaga tccgactgat
     2161 tcagcctttg actttagaca gggaattaga gatcaaacga gatatcgtta ttgattttgg
     2221 tggattcgct cacaatttcg gcacacacca tatttatatc aatgagatac ctcagtcgat
     2281 cgagttccag aattttaaag gaacagctgc acatccaggt ggattgacac caaatatcga
     2341 tggaaatgcc attatcattg cttatatgac cgatttttgg ggaagcagat atcattttac
     2401 gggagaaata aaatttaccg ggacacttga tttgtatgat gggtccaaat taggactgat
     2461 ttacgctcct cgtgcaactg tcacattaga tggtgtttcc ggtgtgttgg atgtccaacc
     2521 agtgaaggaa ggactgaatg ccgctccggg taaagcctat ttttgtagaa gctatcaatt
     2581 gaatgtgatc aatggtagtc aactttatgg accgtatcta gggaaattct acggttttct
     2641 agattcagga gatgagactg gtagtggaaa aacagcgcca ggaatccata tcttaagcgg
     2701 ttcaaaggtc tctcttgatt atgatcgggc agatggcgtt agcgatgaag gagaggcagt
     2761 cgatacgcta cctggtaatg tcatgtttga agtcagtggt tcgggaagcg aattttcggt
     2821 aaatacaaag atcaatatta ccaatgacaa caatcgcgga atcatccaaa tgagaggttc
     2881 aggatcgaaa gtcactgtat cgaatggtgg gaaaatcacc atcaatacag caactacggg
     2941 cggatttcgc ttgcaaggag attctagtca aatccatgta tcaagtggtg gacaaatctc
     3001 ggtcaaaatg gctggagatg acgatcaacc cgggaacaat gggatgcgtt ttgtaggaaa
     3061 aggcctttct ttgatcgtag aaggagccgg atcagttatc gacatcgata agcagagtgg
     3121 gcgttccagc gcagttcgtt ttgagaatgg tacgcaaaag ctgacagtaa ccaatggagg
     3181 ctcattgagg gtaagaaata caggtgatgg caaatcttac gtgaacagac tcaatcaagg
     3241 aaatcaagcg atccaatttt atgacgcttc tggttttcta gaaagtccag gttcagctga
     3301 ttttacagtc actggagaaa aatcaaatat cgatatacgc gcagattccg gagcaactgt
     3361 agatacaact ggagatattg atttaaattt tacggcaggt gaaaaaactt atttagtcat
     3421 ggtcgggaaa acaggggaag ataagaccgg catcatcagt ggggatgtgt tgaatgtgga
     3481 cttagaatct cctacctatt ttgatttcca aaacaaacgg attggaagcg agaccaatgg
     3541 cataggcggc tgggtattcc aaggaaatgg agattcttct ttaaagatcg cccattcaga
     3601 aatcgcttta tggcgaaaaa caggcgcaac attcgataac tttgaaaaag acccggatta
     3661 tttttctgat atgacagact tatcgatcaa tgggaccgac ttaggcaatt tcgtatcaag
     3721 ccctagtgca ggtttaacaa atgaatttgc tcagacaggt gccggaatga aaaattataa
     3781 tcgaatcagt gccaataatc agctcccgat gattgaatcc ttaagagtgc caacgaatgc
     3841 agataaaaaa atctatgggc atgtcgttgt tcccgaaggt gtcgaggcaa agccaagaga
     3901 tgcttggaca ggcgaagtag aagtgacttt acgtattact tacgcagata cgacgaaatc
     3961 atctgtagaa attactgctc tcacgcaagg acaaacagat gaaaatgaag gggcaggata
     4021 taacccatgg ggagaaggcg aacaaggcgg cttgttcgaa gttcaagtac ccaatgatga
     4081 gagattaaaa acggaggatc aagtgcaagt tgttgctgct aaaaaagtaa gaggtggcca
     4141 agaagtgaca gaactggact ctgccaaaac gacagtcgat gtgattcctc ctgaacctgc
     4201 taatttaagt accacattga tcaatgcagc ttctcgcacg atcacaggta caggtgaagc
     4261 aggagccttg gtttcattga aaaaaaatca agctgttttg tcagaaacaa ctattgatga
     4321 tacaggggaa tttgttcttt ctatcccaga aaatcaactt tttgcaggag atgtattaga
     4381 aattgtatta aacgaccaag caggagaagc tactgctaag ggtgtgcaga acaagccaag
     4441 taccaacgat gaaattggga atcacaatcc aagtgatacg ccagttgttt atcatgatgc
     4501 cccgcctttt gcacctgcta cgaagatcgt agtagaaggt ggtctctcat ttcttgcccc
     4561 ttccaaactc gattttggtc agatcaaagc aactggtttg acacaagaag catttggcca
     4621 aatggatata caggaaaaat tatggattta tgatcagcga gaaacgaaaa atccgtggat
     4681 cttaacgata aaattatctc agcctttcac aaatgatgca ggattttcta tgcaggatgt
     4741 cctatatttc aagaaaggag aggagtatca attagtgaat gaagaagaac tggaaattgt
     4801 cagaggacaa aattcaacga atgtgcaagc agattattca gaatatttaa ataacggtcg
     4861 ggcgtttaaa cttgtcttaa ccaaagaaaa tcagatagct ggtaattact cagcagagat
     4921 aacatggaca ttagcagatg cgccgacaga ataaagatca aggaggatga ttgatgaatc
     4981 gaatatggaa taaaagtcat cgaaacaact gctctttact tatgatcctt ctccttggat
     5041 tcatcctttg gcagacacct gtccatgcct ccgaattcaa ttttgcggta gattttgaat
     5101 taccggctaa tcagattgat aagaacaaaa catatataaa tgtaaggatg gagcctggga
     5161 aaacacagga aatcccctac acggtcttta accgaacaga taaatcagta acagttgaga
     5221 cattgatcca ctccgctacg acgaattcaa acggtgtgat cgaatatgga gaatcaaaaa
     5281 gtaaatttga tgaaacatta agttatgata tgaaaaactt agcaaaaaca gtgggagaaa
     5341 taactgttcc tcctcaaagt gcggtcactg agacactttc actgaaagcg ccagaaaaag
     5401 agctggctgg tgtggtcgca ggagggatca cgtttcaaga aaaaaaagag aacgtttcta
     5461 acaaaagtac agttggtgtc gtcaatcagt tttctcaagt gaaagcaatc ttgatttgaa
     5521 atagcgaaaa agagtcttcc ccagatttga aattaaaaaa agcttatgcg gatcaaagcg
     5581 atggaagaaa tgtgattaag gcgaatcttc aaaatccaaa tgcttcttat atgttcggct
     5641 tgactacatc ggttgaaatc tacaaaaaag aaacaaaaga gccttacctt tcaataaaaa
     5701 aagaaaaaat agatgtagca cccaatacaa attttgattt acttgtccca ttagaaggaa
     5761 aaaaattagc tccgggacat tatcaagcgg ttgtgaaggg tgcttggaaa gaaaaacgct
     5821 ggaatctcca taccgatttt gaaataactg atgatgcagc ggaccaattg aatgaaaagg
     5881 atattgattt aaaaaatcag ccagaaacat ttgactggcg atggctgata cttgttggag
     5941 tcattcttat tggcttattt gctggattat ttattt
//
LOCUS       DACBZK010000114         5939 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.120, whole genome shotgun sequence.
ACCESSION   DACBZK010000114 DACBZK010000000
VERSION     DACBZK010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5939
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.120"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            3..761
                     /locus_tag="IVD66_002599"
     CDS             3..761
                     /locus_tag="IVD66_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAP6146769.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(847..1587)
                     /locus_tag="IVD66_002600"
     CDS             complement(847..1587)
                     /locus_tag="IVD66_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6146770.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            1648..2901
                     /locus_tag="IVD66_002601"
     CDS             1648..2901
                     /locus_tag="IVD66_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP6146771.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            3223..3450
                     /locus_tag="IVD66_002602"
     CDS             3223..3450
                     /locus_tag="IVD66_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAP6146772.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            3573..3899
                     /locus_tag="IVD66_002603"
     CDS             3573..3899
                     /locus_tag="IVD66_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAP6146773.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            3967..4680
                     /locus_tag="IVD66_002604"
     CDS             3967..4680
                     /locus_tag="IVD66_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAP6146774.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            4990..5841
                     /locus_tag="IVD66_002605"
     CDS             4990..5841
                     /locus_tag="IVD66_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6146775.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
BASE COUNT         2050 a          975 c         1171 g         1743 t
ORIGIN      
        1 aaatgaaaaa aacaattgca ttaagtaccg ttctagctgg aagtctatta ttatgtacac
       61 aaagtgtttt tgctgagaat aagagctcag ccactacaga aggaacgatt tctgtgacca
      121 aaccagatgc tgcaaatcct gaagacgttg ttccagttcc tcctgttgat ccaaatgatc
      181 ctgatactcc ttttacacct gacgaaccaa atcagggaac atccggatta ctgacgattg
      241 accaagctcc agatcttgat tttggaacaa tcaagttagg tacagcaaaa acagtatatg
      301 ctgcattaca aagcggaacg gacagtactg gagcacaaac acaagtacag aatttcgtac
      361 aagtaacgga taaaagcgga aattatgccg gttggaaatt atcagtcaaa cgaacagaat
      421 ttattggtac aacatctgat acgaataaac taactggttc aaaggtgaaa ttcaaaaacg
      481 ccgtgattcg aaatagcgca actaatagca gtggaatgcc atctaccgtt tctggaactg
      541 gcgctgaagg aatcgaaatc ccagcagatc aggcagtaga tctagtaact gcaggagcaa
      601 atgaagggat tggcacatgg atttattcat taggagagaa tgtggaacaa gggagacaat
      661 cagtggaatt atttgttcct gtatccaatt atgctgtaga caactacgtt tcaacattca
      721 catggtcgtt aacagatgct cctacagaag aggaagcgta aaatcatatc aacgatttca
      781 gggagtggag ccgattcaag gcccactccc tgaaatctgc tatgcttacg tctcagctct
      841 tattcatcaa ctcgaagcag ttttttggaa gtcatggaaa cgttcctttg tcttttcaaa
      901 gatctttcga ccaacgagta aggagtcacc gttgaaaaat tctaacacat aatgagcaga
      961 atcaattttc tgcaattgcg ataagttgat acagtaagat tttaaaagta aaaagtaagc
     1021 atacttttct aactctgtct tcaattgttt taaagaagta ttcactaatt tatcttctgt
     1081 agttgttttg accataactt ggtttttcaa acctttgata ctttcaatat ataaaatttc
     1141 ccgaggatac aggacgagac ttccaccttt ttgatcaata aagattttat cgacatttac
     1201 gatctgctgt tctttccaat tgatctgttc tagcacttga cgaatttgtt cagataaatt
     1261 cctgtctttt ctgatatatc caatcggaag gattttccga ttgatgatct ctactgcaaa
     1321 attcgtataa gcggtgaaaa aaacaatatt actatgtgca ttttttttac gtatttgttc
     1381 ggcgacatca atacctgtga gtgattgctt caagtcgata tcgataaaga aaacatcgtg
     1441 attatcaata gtgcccaact ggatcaactg attgatttga gagatagaag tgagctgcac
     1501 gatattctcg atatgatgat tgaccaattc tctgatgatc cattcgctgt gaaactggtt
     1561 atcttctatg ataaaatact ttttcatatg caggctccta ttaaaaaaat atgtgtacat
     1621 tttgaaacaa aacaatggag gaataagatg gtcgcaacag tgacacttta tttgaccttt
     1681 actttgattt tagatttagg tatctattta ttcttttcga aacaactgct agtaaaaaac
     1741 agctttggtt gtatagcttt gatggtggtg acacttttac ttcctatccc taaagtgagc
     1801 tttccttacc tagttggctt attattgatg tttctttttt attttactac gaaaaacctg
     1861 tttatcagct gtttgatcag taatcttttt tttgctatca ctggactcag cttttttctg
     1921 gtttttgatc tgatggatta tttaggaaag agacatcttg gaacagcaag tttttttgca
     1981 ctacttatcg catttatttt ctatctatta gtaaaaagta tagacaaaca gacgagattt
     2041 ctcaacttgc tttttactta tccaactgaa cactattttg gaggtatttg tattttatta
     2101 agctggggcg tgatttactt ggtattggga agtgttcact tccgctcatc taattatctg
     2161 cttctatctc ttttgtcgat agtcatcagt tttttttctt tgtttttttc cattatgttg
     2221 atcagtttcc aagtaaaaga aagacaacat caggaatcgc ttcaactgta tcaaataaat
     2281 gaagaatatt accatcatct agaggaattc aaacatgatt ataaaagtct actgttttca
     2341 ttaaaaatta ctcttcagga aaataaaaaa gaaacgttgg aatttttaga aatattagaa
     2401 gatcattctg cagctatttt tgaaaaaccg caaatacaac agctaacaaa tattgtatcc
     2461 ccagctgtca ggggtgtctt tttaaaattt ctagaaaaag cagaatcgga gaaaatcccg
     2521 atccaagtag ttattcctgt cgaagtgaaa acaatcccga ttgatctggt tgtttttatt
     2581 cgctgtttat ctatttttat ttctaacgca ttcgatcatc gtgtagccga tcagagtccg
     2641 attacgatca atctgctgga agaaaaagag ggatcacgtt ttagtatagc gaacaaggca
     2701 aatccaacga atttgacgct atcggagatg gtcaaaagag gaaaaacctc taaaaaaaat
     2761 ggcgggttag gtctatacag tgcgaaaaaa atgttggatg tttacgaaaa tgcagaacta
     2821 aaaatcgaat tttcaaaaca gaatcactat ttttttgtag aaatgtatct ggcatctaga
     2881 aagagcaaat cagcctactg acttactgtc aaaggataag tttgaggaaa gtctacacgg
     2941 agatagagac aacaacacag catattcaaa agaaacagaa gcgtgatgac cgttgtcacc
     3001 cttctgtttc ttttgctatg tagttaaaca aagtagttga cacttccgct acttagtatt
     3061 agtacgaaag tatacttcat gatactaagt agataagaag tgaaaagcgg aacccacgat
     3121 cgtcaaaatg ctaactgctt tgcttacacc agataaaggg aagagcaata tcgcttattt
     3181 taggcgtgga gaagcaagca aatccctacg atcacaaaaa aaatgctgac ccagcagtta
     3241 agagagttag aacaagatga aagtatccat cgaaaagcct ataaccaagt cccgcctaaa
     3301 gtagagtact cgctcaccga agaaggaaaa tcattaagag agattctagt agcgttgtct
     3361 gtttgggaag aagaacgtat cgaaaaacaa aaagcctcaa gggaagaaga cacgctactg
     3421 catacacatg gtggctacct aaattattga ttttctatga catttatttt aaataaaaga
     3481 aaacaggagt ttttttaaaa gcatcatcta ttttttatgt aaaaaaatgg tatgattaat
     3541 caagtaagaa gtgattggaa gaaggcaagc aaatgaatag tatggaaaaa gtcaaccagt
     3601 ttagagatga acgtaattgg cgacaatttc ataacgaaaa agatttggct atctctattt
     3661 ctttggaagc atctgaattg ttagaacttt ttcaatggaa aacgccggaa gaagtaaaag
     3721 aaacacaatt agaacgaatc aaagaagaac tggcagatgt attgatctat tcatacatga
     3781 tggcagacaa ccttcacctg gatctagatg agatcattga agaaaaattg atcaaaaata
     3841 atttgaaata tcctgtagaa aaaagcgcag gtgtacgaaa aaaatacaca gagttgtaga
     3901 aatgtgtcat tcggctgttg gaaagagcaa aagaaaaaca gtaaaatgag tctggaggga
     3961 gagaaaatga aaaaaaaagg aaaagcaaaa agatggctag tcaatatcct cttgttcctc
     4021 ttgttattag taggactagc tttgattttc aatgaacaga tcaaggatta ttttgtcaga
     4081 gagacaggag ataaatatgc tatagcgaat gtaacaaaag aagatctgaa aaagaataac
     4141 gataaagatg tcagttttga ctttgatgcg gtagaaccaa tgacgacaga aggggtcatg
     4201 aggtcgcaaa tgagaggaac agatctacca gtgattgcta gtatcgcagt cccttcagtt
     4261 tcaatcaatt taccggtttt caaaggcttg gataatacgt cactacttta cggagcagga
     4321 acattatctc cagatcaaga aatgggaaaa ggaaattatg ccttagcaag ccatcgtgca
     4381 acgaaccctg aattgctgtt tacaccgcta gaaaatttag agatgggtgc caagatctat
     4441 ttgacagatt tagaaaatgt gtatacatac aaaacatttt ttaaagaaaa agttgctcct
     4501 acagataccc aattactgaa tgaagtcgag ggaaaagaaa ttgtcacact aattacttgt
     4561 ggcgacatgg acgccgtcac gcgactagtt gtacaaggag aactggaaag tgttacatcg
     4621 ataaaagatg cgacagatga tatgagatct gctttcaatc tagagacaaa aacattttag
     4681 gatactggga cataagtcgt tacagattaa aaacagccaa aggatatgaa tcgataagga
     4741 aaaaccaatt tgctgaaaaa aagagaaacg caaagaggtg catctctgat ttggttgttt
     4801 tctagataga cttgtgttcc agttttttta ttttttatat gaaaaggctt gcataaataa
     4861 aaattcgatg gtatgatgat tttgaataag aaatggattg ttactgtacg gcaggcaaaa
     4921 ccagaattca gctaagaaac agtaggcgaa ttctaggttt ttttattttt cttgagaggg
     4981 cgaagcaaaa tgaaaattga taaaattttg aataacaatg tcgtcatttc gaaaaatgga
     5041 ttcggggaag aagtcgtttg tatgggaaaa ggactagctt ttcaaaaaaa gattggggac
     5101 gagatttcgc cagaagcggt ccaaaaagaa tttgttttaa gagattcttt tgctaaaaac
     5161 caattccagc agctgatggc tgatattccg gcagaggaga tcgaatgggt caaacaagta
     5221 gtcgaactgg ctgaagataa actaaaagtt gaattttcgc ctaatattta tctgacattg
     5281 accgatcatc ttcattatgc gatcacacga gcaaaagaaa atatccaact gcctaatcca
     5341 ttattatttg aaacaaaaaa attttatccg aaagaatatc aagcagcgaa agaggctctt
     5401 ttgttcgtga aacaaaagac gggtgtggaa ctttctgagg atgaagccgg ttttattgcc
     5461 tttcattttg tgaatagcca acaaggaaac gaagacatgc aagtgacgat gaccgctacc
     5521 acaatggtaa gagatatact gagtatcatc agtaaattct tcggcatcgt gttcgatgaa
     5581 gaatctttga attatcagcg tatcattact catctgcagt tttttgccca gcgttatctc
     5641 aaaggggaag gatctgacga gcaagatgaa tttctctacg cattagttca aggaaagtat
     5701 ccaaaagcgt ttcattgtgt cgaacggatc aatgagtatc ttcgacaaac gcaaaaacag
     5761 gaaatgggga tcgcagagca gatttattta acgattcata ttcaaagagt agtaagtgag
     5821 aaaaaaagca tccaatcata aggattgtta ctgtatggca ggcaaaacct ggattgaaaa
     5881 aataggttca cgaatgtttg tgactgtttt tttcaatctg ggtttttatt ttttaaata
//
LOCUS       DACBZK010000115         5905 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.121, whole genome shotgun sequence.
ACCESSION   DACBZK010000115 DACBZK010000000
VERSION     DACBZK010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5905
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.121"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(95..667)
                     /locus_tag="IVD66_002606"
     CDS             complement(95..667)
                     /locus_tag="IVD66_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP6146776.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(674..1336)
                     /gene="rpe"
                     /locus_tag="IVD66_002607"
     CDS             complement(674..1336)
                     /gene="rpe"
                     /locus_tag="IVD66_002607"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAP6146777.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            complement(1352..1867)
                     /locus_tag="IVD66_002608"
     CDS             complement(1352..1867)
                     /locus_tag="IVD66_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HAP6146778.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            complement(1869..2153)
                     /locus_tag="IVD66_002609"
     CDS             complement(1869..2153)
                     /locus_tag="IVD66_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6146779.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            complement(2187..3515)
                     /locus_tag="IVD66_002610"
     CDS             complement(2187..3515)
                     /locus_tag="IVD66_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAP6146780.1"
                     /translation="MDIVLNAFEWFIGLGSNVFLPLIIFVIGILFGLKPGKAFVSGVT
                     VGIGSIGLGLVLSLLSDGLGTAIQQMGEQYGGGLNILDIGVGVGGPLAYSTSLGILMI
                     PISLILNFIFVVLGWTKTLNVDIWNFWFAIFLGMITQSVTGNFWFGLIGAIVAVILQW
                     FLADRTQKTVSEFFGYPGISITHMMGLSGVLFAKPVNWVFDRIPGFNKIDADAETLTK
                     RFGVLGDTVVIGLIIGIVVGIMAGYDVAGIGNLGIMTAAVMKIMPKMVAMFMEGLMPI
                     AEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMSTSLLLVPISLLLALILPGNKVLPF
                     GDLAFFAFAICLMIPYFKGNIVRSLVGCSLYVVTTLYMATWLAPIITDVFTLASFDVG
                     TAGLVTMLLCGLWPVGLFVLLASYFGVIGIGGLGVVLVGASIYMNKVKKA"
     gene            complement(3529..3984)
                     /locus_tag="IVD66_002611"
     CDS             complement(3529..3984)
                     /locus_tag="IVD66_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP6146781.1"
                     /translation="MYLDKELCLFQLEVKDQKELFQVMSEQLKNAGCVKDSFLEGITN
                     REQEFPTGLEVNQIGFAIPHTDSAHVNSSQICFASLKEPLVFSDMTDKSHEIPVRLVF
                     MLAMSQPHEQIDTLQNLVSLFQNEEKVNELLACTTKEAFIELVHSAGVY"
     gene            complement(3987..5852)
                     /locus_tag="IVD66_002612"
     CDS             complement(3987..5852)
                     /locus_tag="IVD66_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAP6146782.1"
                     /translation="MAVSTKTIYQDIELLEDYVVNYQVTIERLPSLGIKLIGDRKNVE
                     HLISSVENYLEKDIYSPEKRRVEIIKEVLFGDKPVSLTHLSQSFMVSKTSLYNDLRII
                     NKIIGSGEVKLQSSAEGISFTGNEQAIQRAIKQLVFYYANDMESKTFFQVLNMLFDSK
                     VISVIHDLLFNDYSELTEKVSDYYVRSLISTLVIQCNRLLKGHHLTVEEEFLFNSIRY
                     METYIVANGLIEELKAKLNLPFYDADKEYLCRQLFAHRVTNNLKTSNEEYAMSVHKLI
                     ERMSEIEKIDLTQNDRLYQSLLYHVPAMGLRLKKGIKIQNPLLENIKSQYSELFSIVW
                     YAMSILEEEFDVTLTDDEVSLILIHFQIAIEDQSKANNIIIICQYGISSAQLIYNKVR
                     RFLPAKDNVEISTLDKFHLAEIGEVDLIISSLSFDAGGIPLVRVSPLVSKTDYMNIME
                     AYTKYLIEEPSRFIQNELIPKAVKVPTISKFVQSSLVKTGVQVESKEECLDLMISELE
                     ANSLVTEEFRASIFSREKMGNTNLESGVALPHANPSMVIESNIFIVALKNAINWGDRK
                     VKLVIMVSLAEEDVSEIRGVYEELYQFIGQKEMVDRLLQVHDSEKLLRIFQQKGE"
BASE COUNT         1918 a         1148 c          836 g         2003 t
ORIGIN      
        1 aattattaag ttatgtctaa tcaaataaaa aaaccattct catatttgct gaataattag
       61 catttagaga atggtttttt atctttaaaa tctactactc aaaatctgca tgtcgagcaa
      121 acatcgtttc tgagctttca cctgttttat ccattaaaga taacactaaa ctatcaaagg
      181 tgagaaatgc taattgttca aaacttgaac ccataggttg tgaaaaagta tcttcttctc
      241 gttgattttc atctttggta atacctggta atacaagaac agaatctgct aattgaccaa
      301 tcgacgagtc ttttttcatg gtaactaaag caatgcttac accactttga tttgctttgg
      361 ccgctaaatt ttttaaacta cctgtttcac ctgagccaga acagataatt aataaatctc
      421 caggttgcga atgtggtgaa ctaatttcac cgacaaggct gactgaaaaa cctaaatgca
      481 ttaagcgatt cgtaaatgct tgcatggcaa ttccagagcg tcctgcacca gctagaaaga
      541 tgtgtttagc ttgaacaatt ttctcactaa attgttctaa ctctacagaa ttaatacgtt
      601 ttgagttatt ttgtaattct aagataatcg cttctaaata gtttttattt tggtctttat
      661 tggtcatgat cttttacttc acttcctcta atgattgatt tagtttatca atttgttctt
      721 gcggggtatt tttcccattg aagatgaaac cgcctgatac aaaaatatcc gcccctgctt
      781 tagaacaaac tttaatcgtt tgattatcaa tcttgccatc tacttcaata tcatacgtat
      841 aatcattttg tttgcgtatt acatctaact gttcgatttt aactactgtc tcttgaataa
      901 aatgcttatt ctctgttcct ggattgattg tcattactaa tacttgatcg actaaagata
      961 atactggttc aataaaactg actggtgttg caggattaaa agtaatccct acttttgctc
     1021 ctgcttcctt gactaactga atgaccttca ttgcgtgttt ggtagcttca atgtggaagg
     1081 taacaatatc tgctcctgct tctacaaatc ttgtgacaat tttttctggt gtatcaatca
     1141 tcaaatgaac atcaaacaca acgtctgtta gtggacgaat atctttaata acacttggtc
     1201 caaaagccat atctggtaca aaacagccat ccattacatc aatatgcaaa taatcaacat
     1261 tcttttcttt taagatttca aataactctt taacttctgc gataggtgca tttaacaatg
     1321 atggagcaat tgtcattctc tattcccccg tttattctcc cataatcatg agattgattg
     1381 ttctagttcg ctctcttagt tgatcccaat cgacaaaata gacacggccc atttctccta
     1441 ataaaagttt accttcttga acaattaaag tcattgagtt ggttccataa atagatgaac
     1501 gtaaatgtgc atcggtattt agcatgaccc atttttctgc agggtaattg ggatcagata
     1561 atcttgttcc aaaatcaatg tgttttggcc ccggactgtt gtattgattt tcactcgtca
     1621 tttttggaat aatcgtttcc attacattgt tgatgtctac atgtaaataa tcatcaccaa
     1681 aaaagtttgt gtcatgcatc gtttcttcaa aaaagagtga gcaagttgta tgcgggctcg
     1741 aaattactaa cattccattc tcaatacctg ctgtatcaac tgtatctaaa agttcttttc
     1801 gaatatcatg atacgaagga cgccctgaaa ctgtttcaat agtcaaagtg tcatgatgaa
     1861 aacgcatatt aaacacctaa tctttctttt acatctgcat aaatggcatc tgtaccaata
     1921 cctgttaata agcccaagcc attcgttact ttagctttaa ttacatcagg gacaattgtt
     1981 gtacttacta cagcatcata ttcatcaatt ttatttagct catcagcaat tttagattga
     2041 taaattttca cttgatctgt taatccttct tcttccaacc attttgataa ttttgctact
     2101 gcaattgtag aagtagcatg acctgctcca caaataacta ataatttttt catattgatc
     2161 tcttctttct tattttaatt ttatgattaa gctttcttca ctttgttcat gtagatagaa
     2221 gcacctacta aaacaactcc taatccacct attccaatta caccaaagta agatgctaat
     2281 aaaacaaaca accctactgg ccataatcca cataacaaca tagttactaa tcctgctgtc
     2341 cccacatcga aacttgctaa tgtaaacaca tcagtgataa ttggtgccaa ccatgttgcc
     2401 atatataatg ttgtaacaac atacaacgaa catcctacta atgatctcac aatatttcct
     2461 ttaaaataag gaatcattaa acagatggcg aaagcaaaga atgctaaatc tccaaaaggt
     2521 aatactttat ttcctggaag aattagtgct agcaataatg agattggtac aagcaataga
     2581 gaagttgaca taatagttgg atgacccaca gttaacgctg catccattcc aatgtttact
     2641 tggcgaccat ttaacttttt attcgtaaat tctttcgccg cttctgcaat tggcattaaa
     2701 ccttccataa acattgctac cattttaggc ataatcttca tcactgccgc agtcataatt
     2761 cctaagtttc caattcctgc tacgtcatag cctgccataa tacccactac aataccgata
     2821 attaggccaa taacaactgt gtcacctaaa acaccgaaac gttttgttaa tgtttctgca
     2881 tctgcatcta ttttattaaa tccaggaata cgatcaaaaa cccaatttac tggtttggca
     2941 aatagtactc ctgataatcc catcatatgt gtgatagaga ttcctggata gccgaaaaat
     3001 tcgctaacag ttttttgtgt acgatctgct aagaaccatt gtaaaattac tgcgacaatc
     3061 gcgccaatta agccaaacca aaagtttccc gtaacagatt gagtaatcat acctaggaaa
     3121 attgcgaacc aaaagttcca aatatcaaca ttcaatgttt ttgtccaacc caaaaccaca
     3181 aatatgaagt taagaattaa tgaaattgga atcattaaaa ttcccaatga tgtagagtaa
     3241 gccaaaggtc caccaacacc tacgccaata tctaggatat tcaggccacc accgtattgt
     3301 tcccccattt gttgaattgc tgttcctaaa ccatctgata ataaacttaa aactaatcct
     3361 aaaccaatag aaccgatacc aacagtaacg ccggaaacaa atgctttacc aggttttaat
     3421 ccaaataata tcccgattac aaaaataatc agtggtaaaa agacgtttga ccctaatcca
     3481 ataaaccatt caaaggcatt taatacaata tccatctctc tattcctcct aataaactcc
     3541 tgcagaatgt actaactcaa taaatgcttc tttcgtggta catgcaagta attcatttac
     3601 tttttcttca ttttgaaata ggctaactaa gttttgtagt gtatcaattt gttcatgagg
     3661 ttgtgacatt gccaacataa agactaaacg tacaggtatt tcatgagatt tatctgtcat
     3721 atctgaaaat accagtggtt cctttaatga ggcaaaacag atttgagagc tatttacatg
     3781 tgcggaatct gtatgtggga tagcaaaccc aatttgattt acttctaatc cagttggaaa
     3841 ttcttgttca cggttggtga taccttctaa gaaactatct ttcacgcaac cagcgttttt
     3901 taattgttca gacattactt gaaacaattc tttttgatct ttcacttcta attgaaataa
     3961 acataattct ttatctagat acatttttat tctccttttt gttgaaaaat tcttagtaat
     4021 ttttcgctat catgaacttg taacaagcga tcgaccattt ctttttgccc aataaattgg
     4081 taaagttctt catatactcc tctaatctca gatacatctt cttcagctaa actaaccata
     4141 atgactaatt tgacttttcg atcgccccaa ttaatcgcat tttttaatgc tacaataaaa
     4201 atgttggatt caatgaccat tgatggattc gcatgcggta aagcaacacc actttctaaa
     4261 ttagtattcc ccattttctc tctagagaag atagaagcac gaaactcttc agtaactaat
     4321 gaattggctt ctagttcgga aatcatcaaa tccaaacatt cttctttgct ttccacctgt
     4381 actcctgttt ttactaaaga tgattgaaca aatttagata tggtgggaac tttaaccgct
     4441 ttaggaatca gttcattttg aataaatcgc gaaggttctt ctattaaata tttagtataa
     4501 gcttccataa tattcatata atctgtttta cttaccaatg gagataccct tactaagggt
     4561 ataccacctg catcaaagga aagagaggaa ataatcaaat caacttcccc aatttcagct
     4621 aaatgaaact tatctaaagt tgatatttct acattatctt ttgctggtaa aaaccgtcga
     4681 actttattgt aaattaattg cgcagaagaa ataccgtatt ggcaaataat gatgatatta
     4741 tttgctttgg actgatcttc aatagcaatc tgaaaatgaa tcaaaattaa ggaaacttca
     4801 tcgtccgtta aagtcacatc aaattcttct tcaaggatgg acatggcgta ccatactatg
     4861 ctaaagagtt ctgaatattg agatttgata ttttctaata acggattttg aattttaata
     4921 ccttttttta aacgaaggcc cattgctggc acatgataca ataaggattg atataatcga
     4981 tcattttgag tcaaatcaat tttttcaatc tcactcattc tttcaatcaa tttatgaacg
     5041 ctcatagcgt actcttcatt gctggttttt aaattatttg tcacacgatg tgcaaatagt
     5101 tgacgacata gatattcttt atctgcgtca taaaatggaa gattcaattt tgccttcaat
     5161 tcttcaatta aaccatttgc cacaatgtac gtttccatat agcgaatgct attgaagagg
     5221 aattcttctt caacagttaa atgatgacct ttcagtaaac ggttacattg gataactaaa
     5281 gtagaaatca atgaccgaac atagtaatca gaaacctttt cagtcagttc actgtaatca
     5341 ttgaatagca aatcatgaat gacactaata acttttgaat caaacaacat atttaaaact
     5401 tgaaaaaatg tttttgattc catgtcattc gcataataga atacaagttg cttgattgct
     5461 cgttgaattg cttgttcatt accagtaaaa ctaattcctt ctgcagatga ctgcaactta
     5521 acttctccac tgccaataat tttattgata attctcaggt cattgtataa cgatgtttta
     5581 ctaaccataa aactttgaga caaatgagtt aaagaaacag gcttatcacc aaacaaaact
     5641 tctttaatga tctcgacacg tcttttttct ggagaataaa tatctttttc aagataattt
     5701 tctaccgatg aaatcaaatg ttcaacgttt ttcctatcac ctatgagttt gatacccaaa
     5761 gaaggtaatc gctcaattgt tacttggtaa ttaactacat aatcttccaa caattcaata
     5821 tcttgataaa tggtcttggt cgacactgcc aatttatcac taaaaaaaga agcgggttta
     5881 aagtcttctt gtcgacttaa taatt
//
LOCUS       DACBZK010000116         5689 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.122, whole genome shotgun sequence.
ACCESSION   DACBZK010000116 DACBZK010000000
VERSION     DACBZK010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.122"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(488..1297)
                     /locus_tag="IVD66_002613"
     CDS             complement(488..1297)
                     /locus_tag="IVD66_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP6146783.1"
                     /translation="MVKESVIGKKELRSIFWRSFFMQSSWSFDKMMAYGQMNGIERSL
                     RKIYPNDDDYYTALQRHTETFNITPHIAPFVMSLSVTMEEENAKNPEFDTDAINKIKT
                     GLMGPLSGIGDSFFWGTFRVIAAGIGISFAQQGNILGMILYFTLYTAIHFIFKWLATK
                     YGYVLGTKFIDDTEDNHMIDKLSHGASILGLTVIGAMIGTMVTLNTSLKFTVGGAETS
                     LQSIFDQIFPGLLPLGITFLCVWLYSKGHKTITIILGIFVLCFLGTLGGIF"
     gene            complement(1297..2043)
                     /locus_tag="IVD66_002614"
     CDS             complement(1297..2043)
                     /locus_tag="IVD66_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6146784.1"
                     /translation="MIQAILIALVAFLASIDEYTFGASMMGRPLFTAPFVGLILGDLE
                     SGIIIGATLESMFMGSIMVGSATPPEVYASSVLGTAIAIQSGQGVGTAVALTLPLSIF
                     LQMWRNFAYAMPITYFNNKMDEALVNHDFKKAQKYHYVAQPLIVGVPSAILVFVATYF
                     GVSTINAMIKLIPQVVLDSFDVAAGVLSCVGLALLIKMMANKAMMPYLFLGFVGVMYL
                     KMDVVGVAVVGLCLALLAVQKLTFEEEEDL"
     gene            complement(2061..2528)
                     /locus_tag="IVD66_002615"
     CDS             complement(2061..2528)
                     /locus_tag="IVD66_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6146785.1"
                     /translation="MIKLLRVDERFVHGQVAFAWTNNLGANCIFVASNEIATNNLRKK
                     TLKMAVPTGTKFVVKDMTEAISVLNGEKIKKYQVFLIVGTVEDAYEITQHVPEIKEVN
                     LGNLKKNENRKMITSSVYLNEQELDLVKKMTENGITVQCQAVPTDKKINPLHD"
     gene            complement(2528..2938)
                     /locus_tag="IVD66_002616"
     CDS             complement(2528..2938)
                     /locus_tag="IVD66_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP6146786.1"
                     /translation="MRKIVIATHSMMAKGLKDTLEFIIGPQKSLLAITAYIDSDYSIN
                     QEIEQLFSDLAPDDELIVTVDLLGGSVSNAFSEQIGKDNFYLISGVNLPLLLELCLSG
                     EQDTKKLIQKAMNSGNEGIVLVNELLEKTEEDDF"
     gene            complement(2949..3962)
                     /locus_tag="IVD66_002617"
     CDS             complement(2949..3962)
                     /locus_tag="IVD66_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009141002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP6146787.1"
                     /translation="MLGFSEERFLSVLNGAVKNIETINQVADAISEKGFKNLYLVGSG
                     GTYATISPLAYLLSTHSELDYYHEIAAEVVCSQPKKINKDTVLITSSLTGTTQETVDV
                     VKYANSQGATTIAFVGNAATPLGEIVDYAIENDADNDTLVEELQLQFFALGARLMKNN
                     GEFPEYDEFIQTLQKMPEVLLSVRQQNDQKALEFAEKHKNTEFHMFVGAGNTYGAAYE
                     YAMCVLEEMQWIATKSIHAAEFFHGTIEMTDKSMSFVLLKGEDQTRPLVDRVERFVNK
                     YSDVVTVFDTADFELAGVPSAMRQYVAPMVMATALERVSAHFEKVRDHSLDIRRYYRT
                     VEY"
     gene            4179..4913
                     /locus_tag="IVD66_002618"
     CDS             4179..4913
                     /locus_tag="IVD66_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6146788.1"
                     /translation="MNTEELTNKLIQDIEQEKYKYAQAIPSERDFVQIYEMNRSAVKK
                     AIQQLVNKEYLLKIHGKGTFVKKNIHEHLQIKFHGLSELLEREGIQPSSLILASEIKP
                     AGHIVGKALQLEPTEEVFHLVRLRSGDGEPISIEDTYIPLNLIPDLQAFDFQIFSFYS
                     TLAAYHYQIENIYQTISSSKVSNKEARLLKTSLNRPVISLAITAVTTNEQAVEYTEVV
                     VLPEFAAIYTKNVHQGKEMKIYAQID"
     gene            4897..5607
                     /locus_tag="IVD66_002619"
     CDS             4897..5607
                     /locus_tag="IVD66_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6146789.1"
                     /translation="MPKLINLLAYDLIDKIIAYIHEHHLTPGTKLPSERDLSEMFNVN
                     RTTLRGALQKLVDNGTLRAQTNSGYYLTAPKFEKNAHHFFTPIEDSLLSKQRLQLKAT
                     ALSPKKAAALCPELNDFKQQQPQAYLEYIDAEAISLMLLIPMETLKKSNFSDNPFQDF
                     KSLAYTRSQEISLITDNDVAADLLGVDKEEVLLFVREEIRAGKELAAIALGYTISRRC
                     NIQVNVATTLQSGSVAKF"
BASE COUNT         1832 a         1195 c          943 g         1719 t
ORIGIN      
        1 aagcgacaaa aaccacgagc aggtccattc atcctcaaac ctcggtgatc ttcgcggttt
       61 aacaccatca gaagaaatgc acaaaaataa taaggagagt ctgagacata aataaattcc
      121 cagactttta gtgagtctaa atccgaataa acggtgggtc gaaagcaact ctagctgcgc
      181 gtcgatcgca gcaatctcta ggtgctatgt tcggataaat ggtggtcaaa agtcagattt
      241 tcggccattt cgtaacagcc aaccagacaa aaagcgtctg ttttgtcttc tactccaatt
      301 gctcaaatct tagcgacttt tggcttggtc ttactctaaa cagtttgtaa gcctaaactt
      361 tatttgctgt ttgtttctaa gatcaaagca aaactacttt ttagttggtt acttttacaa
      421 gttcttttta ctgttgaata aatgtaaatc ttaagaacaa atatttactt ctataattcc
      481 aagtttctta aaaaattccg ccaagtgtac ctaaaaagca taaaacaaaa attcctagaa
      541 taattgtgat cgttttatgc cctttggagt aaagccagac gcataaaaag gtaattccta
      601 atggcagcaa gcccggaaaa atttgatcaa aaatactttg taatgaagtt tcagctccac
      661 caaccgtgaa ttttagtgac gtatttaaag taaccatcgt gcctatcatc gcgccaatta
      721 ccgttaaacc taaaatcgaa gcaccatgag ataatttgtc aatcatatgg ttgtcttctg
      781 tatcatcaat aaatttagtt cctaaaacat agccatattt tgtcgccaac catttaaaaa
      841 taaaatgaat ggcagtatac aaagtaaaat aaaggatcat gcctaaaata ttcccttgtt
      901 gagcaaaaga aatacctatg ccagccgcaa taacccgaaa agttccccag aaaaatgaat
      961 cgccaatacc tgataaaggt cccattaatc ctgttttgat tttattaatt gcgtctgtat
     1021 caaattcagg atttttagca ttttcttctt ccatggtgac ggacaagctc ataacaaaag
     1081 gcgcaatatg cggtgtaatg ttaaatgttt ccgtatggcg ctgcaacgct gtataataat
     1141 catcatcgtt cggatatatt ttacgtaagg aacgttcaat accattcatt tgtccatatg
     1201 ccatcatttt atcgaaggac caagaggatt gcataaaaaa ggagcgccaa aatatacttc
     1261 ttaattcttt tttcccaata acactttctt ttaccattat aaatcttcct cctcttcaaa
     1321 agttagcttt tgaacagcca gtaacgctaa gcaaagtccg acgacagcca caccgacaac
     1381 atccattttc agatacatta cgccgacaaa tcctaagaaa agataaggca tcatcgcttt
     1441 attcgccatc attttaatta ataacgctag cccaacacaa gaaagcacac cggccgcaac
     1501 atcaaagctg tccaatacaa cctgaggaat caacttgatc atcgcattga ttgtagacac
     1561 accaaaataa gtagctacaa aaactaaaat ggccgatgga accccaacga ttaaaggttg
     1621 agccacataa tgatattttt gtgctttttt gaaatcatga ttgactaatg cctcatccat
     1681 tttgttgtta aaatacgtaa ttggcattgc ataggcgaag ttacgccaca tctgaagaaa
     1741 gatggacaaa ggtaaagtca acgcaacggc agttcctact ccttgacccg attgaatcgc
     1801 aattgctgta cctaaaacac tggaagcata aacttcaggg ggcgtcgcac tccctaccat
     1861 aattgagccc atgaacatgg attccaaggt ggcaccaata ataattcctg actctaaatc
     1921 tcccaaaatc aaaccgacaa aaggcgctgt aaatagcggt ctacccatca tcgatgcacc
     1981 aaatgtgtat tcatcaatag acgccaaaaa agctaccagt gcgattaata ttgcttgtat
     2041 catattcttc ccctcctctt ttagtcatgc aaaggattga tttttttgtc cgttggtaca
     2101 gcctgacatt gaactgttat cccgttttca gtcatttttt tcaccaagtc cagttcttgt
     2161 tcattcaagt aaacggaact agtaatcatt ttccgattct cgtttttctt taaatttcct
     2221 aaattcactt ctttaatctc aggtacgtgc tgagtaattt cgtaggcatc ctccaccgtc
     2281 ccgacaatta aaaatacttg gtatttcttg attttttctc catttaaaac agagatggcc
     2341 tctgtcatat ccttcaccac aaattttgtc cctgtaggaa cagccatttt tagtgttttt
     2401 ttgcgcagat tattggtagc gatttcatta cttgcaacga aaatacaatt tgcacctaag
     2461 ttatttgtcc aggcaaaagc aacttgccca tgaacaaaac gttcatctac tcgtaataat
     2521 ttaatcatta aaaatcatcc tcttctgttt tctctagcaa ctcgttcacc aaaactatcc
     2581 cttcattccc gctattcata gctttttgga ttagtttttt cgtgtcctgt tcacctgata
     2641 agcaaagctc taaaagcagc ggcagattta caccgctgat taaataaaaa ttgtctttac
     2701 cgatttgttc ggagaaagcg ttagacacgc ttcctcccag taaatctacc gtcacaatta
     2761 attcgtcatc aggcgctaag tcggaaaata gctgctctat ttcctggtta atggagtagt
     2821 cactatctat atacgcagtt attgctaaaa gtgatttttg aggaccaata ataaattcta
     2881 aagtatcctt taagccttta gccatcatgg aatgcgtcgc aattacaatt ttcctcatag
     2941 ctcttacctt aatattccac agtccgataa taacgacgaa tatctagtga atgatcccgc
     3001 accttttcaa aatgagcact cactcgttct aaggccgttg ccataaccat tggcgctaca
     3061 tactgacgca tagcgcttgg tacacctgct aattcgaaat ccgcagtgtc aaaaaccgtc
     3121 acaacatcgc tatatttatt tacaaaacgc tctacgcgat cgactagcgg acgcgtttga
     3181 tcttcacctt ttaataacac aaaactcata gatttatcag tcatttcaat agtcccatgg
     3241 aaaaattcgg ctgcatggat cgacttggtg gcaatccatt gcatttcttc cagtacgcac
     3301 atagcatatt cataggcagc cccataagta ttcccggctc caacaaacat atgaaattcc
     3361 gtatttttat gtttttctgc aaattcaagt gctttctgat cattttgttg ccgaacactt
     3421 agtaatactt ccggcatttt ttgtaatgtt tgaataaatt catcatattc aggaaactca
     3481 ccgttatttt tcatcaggcg tgcacccaaa gcaaaaaact gtaactgaag ttcttctact
     3541 aatgtatcgt tgtcagcatc attttcaatc gcataatcca cgatttcccc gagtggtgta
     3601 gcagcatttc ctacaaacgc aatcgtcgtt gcaccttgac tattggcata cttaacaaca
     3661 tcaacggttt cttgagtcgt accggttaat gaagatgtga ttaacactgt atctttatta
     3721 atctttttcg gctgtgaaca aaccacctct gcggctattt catgataata atcaagctct
     3781 gaatgagtgc ttaacagata agctagcggg ctgattgtgg catatgttcc accagagcct
     3841 accaaataaa gatttttaaa tcccttctca ctgattgcat ctgccacctg attgattgtc
     3901 tcgatatttt ttactgcacc atttaatact gatagaaaac gttcttcgct aaaacctaac
     3961 atagttaaaa acctccaagt caataatttg aaaaatatat ttgcaaatgc cggcacatta
     4021 acaaaccact taaccttttt tatataccac ctgttaacgt ttttaatgta ccacttatag
     4081 aaaacgctgt caatagtttt taaccacttt tatttttatt tgtaccaaaa tccttttttc
     4141 atgtataata aacaaaaata gactctggag tgtaacgtat gaatactgaa gaactaacga
     4201 acaaattaat acaagacatt gaacaagaaa aatataaata cgcgcaagct attccttcag
     4261 aacgtgattt tgttcaaatt tatgaaatga atcgttcagc cgtaaaaaaa gccattcaac
     4321 aattagtaaa taaagagtac ctactaaaaa tacatggcaa aggaactttt gttaaaaaaa
     4381 atatccatga acatttgcaa atcaaatttc atggtttgtc tgaattgttg gaacgggaag
     4441 ggattcagcc tagcagctta attttagctt cagaaataaa accggctgga cacattgtcg
     4501 ggaaagcttt acagctggaa ccaactgaag aagtatttca tttggttcgt ttaagaagcg
     4561 gcgacggtga gccaatttct attgaagaca cttatattcc attaaatctc atacctgatc
     4621 ttcaagcttt tgatttccaa attttttcat tttattccac attggctgct tatcattatc
     4681 aaattgaaaa tatctatcag acaatttcca gctcaaaagt gagcaataaa gaagcccgtt
     4741 tgttaaaaac cagcttaaat cgtccggtaa tcagccttgc tatcactgcg gttacgacaa
     4801 atgaacaagc ggttgaatac actgaagtag tggttttgcc tgaattcgcc gccatctata
     4861 ctaaaaatgt tcatcaagga aaggagatga aaatctatgc ccaaattgat taatctgttg
     4921 gcttatgacc tgattgacaa aattattgct tatattcatg aacatcattt aacccccgga
     4981 acaaaactgc cttcggaacg ggacctatca gaaatgttta atgttaatcg aactacctta
     5041 agaggcgcgt tacaaaaact ggtggacaac ggcaccttac gggcgcaaac caatagcggc
     5101 tattatttaa ctgcgccaaa attcgaaaaa aatgcccatc atttctttac accgatagaa
     5161 gattctctgc ttagtaagca gcggctacag ctaaaggcaa cggctctttc accgaaaaaa
     5221 gcagcagctc tttgtccgga actgaatgat ttcaaacagc agcaaccaca agcttattta
     5281 gaatatattg atgcagaagc aattagcttg atgttattaa tccctatgga aacattaaag
     5341 aaaagtaatt tctcggacaa tcctttccaa gattttaaaa gtttggcata tacgcgttct
     5401 caagaaattt ctttaataac tgacaatgac gttgcggcgg acttgctggg agttgacaaa
     5461 gaagaggttc tgttatttgt acgagaggaa ataagagccg gtaaggagtt ggcggcgatt
     5521 gctttaggtt atactattag tcgccgctgc aacatacagg ttaatgttgc tacgaccttg
     5581 caatccggtt ctgttgcaaa gttttaaatc tactatcaga taaggtagaa taatagaaaa
     5641 agatagcagg aggaatgacg atgagtcatt ttaaaggaaa gcaatttca
//
LOCUS       DACBZK010000117         5666 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.123, whole genome shotgun sequence.
ACCESSION   DACBZK010000117 DACBZK010000000
VERSION     DACBZK010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.123"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            386..1711
                     /locus_tag="IVD66_002620"
     CDS             386..1711
                     /locus_tag="IVD66_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAP6146790.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            1704..2054
                     /locus_tag="IVD66_002621"
     CDS             1704..2054
                     /locus_tag="IVD66_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146791.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            2051..2230
                     /locus_tag="IVD66_002622"
     CDS             2051..2230
                     /locus_tag="IVD66_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146792.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            2366..2656
                     /locus_tag="IVD66_002623"
     CDS             2366..2656
                     /locus_tag="IVD66_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAP6146793.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            3024..3812
                     /locus_tag="IVD66_002624"
     CDS             3024..3812
                     /locus_tag="IVD66_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP6146794.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQG
                     NATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVG
                     SEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKL
                     SETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGTKIFKTYIRRT
                     ITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            3799..4125
                     /locus_tag="IVD66_002625"
     CDS             3799..4125
                     /locus_tag="IVD66_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146795.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            4474..5514
                     /locus_tag="IVD66_002626"
     CDS             4474..5514
                     /locus_tag="IVD66_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HAP6146796.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
BASE COUNT         2154 a          812 c         1020 g         1680 t
ORIGIN      
        1 tttcaatgtt ataccagtgt ctatttaggg taaaccttat atagacaaaa actaatgatg
       61 gaggaaatag tatgagaatt ttttgtaagt gtctactgat aacttattct caaatgttgt
      121 aaggatttta ttcatttgtt aatattaaag aacggaactc caaaaaagtc cgtactctaa
      181 tttgcagtct ctcactcttt tagagtgaga gtttttatta gattttcaaa ttaattagta
      241 aagtgataga ataaattgat catacaaatc aaaagaagaa gcagggtgat agcataccta
      301 tgcttctttt tttatgtatt tagctatttc ttctttacaa tatcgaacat atgtttgtat
      361 aatgtgaaag aatggagtgt tatttatgat ggattattca aaagagccag taaatgatta
      421 ctttttaatc gatatgaaaa gcttttacgc aagtgtcgaa tgtatagaaa gaaatttaga
      481 tccattaaca acagaacttg ttgttatgag tcgagctgat aatactggtt caggattgat
      541 attagcttct tctcctgaag caaaaaagcg gtatggtatt acaaatgtga gtagaccacg
      601 tgacttacca caaccatttc ctaaaacact acacgttgtt ccaccacgta tgaacctata
      661 tatcaagcga aatatgcagg taaataatat tttcagaaga tatgtggctg atgaagatct
      721 actgatttac tcgatcgatg aatcaatctt aaaagtgacc cgatcactga atctttttac
      781 gactgaagga acacgaagtc aacggagaaa gaagctggct caaatgatcc aggagaatat
      841 taaagaagag ctaggattga ttgctacagt aggtgtcgga gataatcccc ttttggctaa
      901 actagcctta gacaacgaag caaagcataa tgaaggattt gttgcggaat ggacgtacga
      961 aaacgttcct gaaaaagtat ggaatattcc tgaaatgacg gacttttggg gaattggctc
     1021 tcgaatgaaa aaaagactca atcagatggg gattatgagc attagagatc ttgctaactg
     1081 gaatccttat acgattaaga atagactagg tgtgattggc ttacagctgt acttccatgc
     1141 taatgggatc gatcgaacag atatagcaat cccaccagaa ccgacaaagg aaaaatcata
     1201 tggaaattca caagtgttac cacgagatta tactagaaga aatgaaatcg agctggtggt
     1261 aaaagaaatg gcggaacaag tagcgatacg cattaggcag cataactgta aaacaggttg
     1321 tgtccattta cacattggca cgtcgatctt agaaacgaga ccagggtttt cacaccagat
     1381 gaagatccct atcacagata atacaaagga attgcagaat tattgtcttt tcttgtttga
     1441 taagtattat gaaggacaag aagtaaggca tgttggaata acctatagca agcttgtgta
     1501 caccgattcg cttcagctgg atttatttag tgatccacaa aagcaaattg acgaagaaaa
     1561 tttagataaa attattgaca agattcggca aaaatatggt tttacgtcga ttgtacatgc
     1621 ttcttcaatg ttagaaggcg ctagaagcat tactagaagc acacttgttg gtggtcatgc
     1681 gggcggaaat gggggaatta aaaatgattg attacaatga tcgtggacgt ttaaagtggg
     1741 cagggtttta tttatctgat catactgaag aaattgatgc cgacaatgaa caacgaacca
     1801 gtcaaaattt agcaaaagaa caaatgacga ctgaagagat tgcggaagta ttgaacgctg
     1861 cagtcataaa aaatagatca gtatctattc aaaaagaaga acgaaacgct gaaggatact
     1921 atccagaaga tatcattggc aagatcttag gtagtgatga gctggggatc tacgttggaa
     1981 aagacaaaat tcactacgac gaaatacgtc atatcgaatt ttaccaggat aataaatgga
     2041 gtcgattaga atgaacatta tccagcaata tgagctaaag tatataacct ttgatcagct
     2101 atcagaagag atttggggtt atggccaacg tttgataaat gaggttggtg ttgagcgctt
     2161 ctctttctat gtagaagctg cagcaggtta tcataatttt aggttttata tcttcccgtt
     2221 atatatataa ggtattttac ggattctata gagttatctc tatgaatcct tttttgtttt
     2281 tacaaatagg agtagatact agaataatgc gtgtgttaaa ctattattgc aaacgcaata
     2341 ataaaagaaa gtaggcttac gcaccatgtc tatcaataca tttgtttact cgcacccgat
     2401 caatgtttac attatcaaga atttaggaat cactgtagaa caattttgtg agttatatgc
     2461 ctacccacaa ggaacggttg caagctggat aacccgacaa cgtagaataa aatcattacc
     2521 tgcttcattc gtttatgatt taagcctggc ctctagttta aacatgtctg atgtttatga
     2581 aaagctcctg tctttagaaa aagaatatga ttccttcaag attaaacatg ataaaaaaat
     2641 aaaaaaacat atataatatc aatcacaatt gtataatatt acgatatctt aatatcatga
     2701 tatcgtaata ttgttttttt ctaagaaaat gcactataag aagggaatta ttagtaacaa
     2761 tatagacagt ttagtaatgt ttaaattatt ctagttgctg ctcgcaaaac atatttctta
     2821 tcattaaaaa aaaattttaa agtaataaaa agtgattatt ttaatttcga ataacatatg
     2881 aataatcttt atatccgaac cgatatatat ctttaaaaca aaataatcac acaatattac
     2941 aatataatgc atatacgata ttgcaatatc acaatattat gatataatta tattataata
     3001 taagatgaat gggggatatt ttaatggcaa gaatattgtc agtagccaat caaaaaggtg
     3061 gagtttctaa aactacgact agcgttaatt tagcagcatg tttgaaattt gtttacggta
     3121 aaaatgtact tttagtggac attgatcctc agggaaatgc tacagataat gtaggtttcg
     3181 atatagatgg aacaaaccaa cctacaattt atgaagtatt aaaaggggag gctgacatta
     3241 cagatgctat tctggactat aaaggaattg atgttttgcc agccgacata gccctttctt
     3301 ctgcagagag ggaatttact caagtaggaa gtgaacacag gcttaaaaga gtacttcaac
     3361 caatcaagga caactatgat tatattataa ttgattgtcc accaagttta ggaatgctta
     3421 cagtcaacgc atttactgtt tctgatgaaa ttatcattcc agttgaagct gcgtatttct
     3481 cattaaaagg actaataaag ttaagtgaaa ctattgaaac ggtaaaagaa tatacgaacg
     3541 acaagcttga agtacgagga gttctattta ctaagtataa taagcgttat aacatttcta
     3601 aagaaatgac gtctgcagca accgaaattt ctagagtcat tggtacaaaa attttcaaaa
     3661 cttatattcg taggacaata accgttgacg aagcgcaagc tgctggatca gatctaatca
     3721 attttaataa accctcaaca gctgaagatg actataaagc atttacagaa gaatatttaa
     3781 aagaagttgg tgattttgat ggcagaagat aatcgcagtc aagctgcagt aagtagatta
     3841 ctaggaaata aaaataaaaa gaattttaaa tcaaaagaag tagaagaaat cgaattaacc
     3901 aagaaaaata taagtaaagt cataaaagat caaggaagta gtgtaagaac agcagatagc
     3961 attcgtataa atccaattct aatgtcagca ctcaaatatt ggacgactat tgctgaatca
     4021 gacaaaagta aaccagacgt tatagaagat gcgctattaa agtccatacc tgaagaatac
     4081 ttgattgaag gatataaact agcaaagaaa caaaataaaa tttaatttac attcaatatc
     4141 acgatatcat aatatcgtga tatttttttt ataaaaatca gtagtatcaa agctgataag
     4201 tcgcttatct tcatattgta atattacgat atcgtgatat aatattattg taatatcgtg
     4261 atatagttac tatgagctta aaccttgaaa tagagcggtt tgctttaatt tattttttaa
     4321 ggtaaactaa aaaaagataa aaaaagacta ctgctttaac aaagtttggc gacttatcag
     4381 cagtagaaaa atatatagtg gatagatata tttgtttaat tcattgtaac atagttttga
     4441 acaaaacgct atcctacaga aagaggattg gctatgaatg attttaatta ttacaaatca
     4501 aaagaaattt atcgtgaaaa atattatcaa atgcctaagg tattttttac taacgaaaaa
     4561 tacatggatc tatcaaatga tgcaaaaatt gcttatatgc tacttaaaga tcgatttgat
     4621 tattcagtca aaaataactg ggtagattct gatgataata tatttttcat attcacagtt
     4681 gaagaattaa tgaaattgtt acaatgccgc gaaggtaaag tatctaaaat caaaaaggaa
     4741 ttagaaaaag caggtcttct gaaacagaag agaggaagag taaataaacg tgacggtaag
     4801 attgaatcca tgcctaattt attgtactta ggcaagccag aagtaacgaa tcaagacgtc
     4861 tttaaaatca tggaagagga agacaatact gataccaccg taattgcgaa aatcgcaaat
     4921 acggcaaaac cgcgagaaat caatgatacc accgtaattg cgaaaatcgc aaatacggca
     4981 aaatccagtc atatcaagga ctcaaccgta attgcgaaaa tcgcagacaa tctattctat
     5041 tctaattcta tagacactaa tagacacata atagacactg aaactgatca gttacaaaat
     5101 caagttttac tagataactt cgtcgacatc atgaaagagg acagtataaa tacatttgta
     5161 ccagaaaatg tattaaactt gataaaaaca ttttctagta cttacgaaga cgctcaaaaa
     5221 accgtccaaa ctattcataa tgcaaagaaa aaagctgaag aattagagca aacagttgtt
     5281 gtttatgaag aactggaatc ttatggaatt gatgctgaca aaggattata tatgactttg
     5341 ctgaaagctt atcaaaaaca aaaaactgaa aaagtaaaca atttgcagaa tctaattttc
     5401 gtttatgtaa aaaattggtt tgtcgaaaaa gctattgcgg caaagcttgc aaacgaacaa
     5461 agagaaacat ttaacgaatt accaacagtt agtacggaaa attggctaga gtagttgata
     5521 aaaagcgatc actataaaaa tgatcaattt taaattagaa cttttttatg attttaattt
     5581 tattacaaat gttacaaata aatagctatt attccggagt ttttagatta aaagtttatg
     5641 aaaacaatca caaacgtagg ttttaa
//
LOCUS       DACBZK010000118         5466 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.124, whole genome shotgun sequence.
ACCESSION   DACBZK010000118 DACBZK010000000
VERSION     DACBZK010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.124"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            133..1107
                     /locus_tag="IVD66_002627"
     CDS             133..1107
                     /locus_tag="IVD66_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP6146797.1"
                     /translation="MRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAGQYLFD
                     KELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGAMTICL
                     SNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWETCLNEF
                     DKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFMEMQWIN
                     SNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVLDQADF
                     DLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1089..1550
                     /locus_tag="IVD66_002628"
     CDS             1089..1550
                     /locus_tag="IVD66_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP6146798.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1600..2064
                     /locus_tag="IVD66_002629"
     CDS             1600..2064
                     /locus_tag="IVD66_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6146799.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2078..2827
                     /locus_tag="IVD66_002630"
     CDS             2078..2827
                     /locus_tag="IVD66_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6146800.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2827..3657
                     /locus_tag="IVD66_002631"
     CDS             2827..3657
                     /locus_tag="IVD66_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP6146801.1"
                     /translation="MENSTEKKRLITKKDLHKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTPFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3657..4304
                     /locus_tag="IVD66_002632"
     CDS             3657..4304
                     /locus_tag="IVD66_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP6146802.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4402..5178)
                     /locus_tag="IVD66_002633"
     CDS             complement(4402..5178)
                     /locus_tag="IVD66_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6146803.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLTESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            5260..5403
                     /locus_tag="IVD66_002634"
                     /pseudo
     CDS             5260..5403
                     /locus_tag="IVD66_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608918.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
BASE COUNT         1872 a          739 c          973 g         1882 t
ORIGIN      
        1 attttattat ataaaattgt tataaaaaat tttttttgaa aaatagtatt gcaaaataaa
       61 gcaatttcat agataatagg tatcgtaaag ttatataact ttataatacc tattagagtg
      121 agggataaag aaatgagaca actacacaaa gaacagattg aaacagcaat ggcagcgtta
      181 aaggaaaaga caattgatca tgtatatttt acagcatgtg ggggttcaca agccgtttta
      241 atggctggtc aatatctatt tgataaagaa ttaactgtac cttgtcatgt ttatactgct
      301 aacgaattta actatgctat accaaaagga ttatctgaaa attctttagt tatcacttgt
      361 tcccattctg gcacaacacc agaaactgta gaagcaacaa aaaaagcaag agaatttgga
      421 gcaatgacta tttgtttatc taatgaagaa ggatctcctc tatgggaagc agctgaatat
      481 cctgttcact atgattgggg taaagatgtt gatgctagtg atttaaataa aggaattctt
      541 tatggtttat tatttaatat tttacttgtt ttagatggct ctaaaaaatg ggaaacttgc
      601 ttgaatgaat ttgataagtt aaatgatctt gttattgctg aaaagagcaa atttgaaata
      661 actgctaaag aatggggtaa aaaccaaaaa cgagataaaa ttatttacac aattggtagc
      721 ggtattaatt acggagaaat ttactccaca gcagcttgct ggttcatgga aatgcaatgg
      781 attaattcta atgctattca ttctggggaa tttttccatg gtccttttga aatcactgat
      841 tatgatgtac cattcatctt agtgaaaagt attggagata caagattttt agatcaacgg
      901 gtagaagact tcactaaaaa attcagtaat aaattaatgg ttttagacca agctgatttt
      961 gacttagaat ctatagatag tgtagcgaaa gaatatattg cagctgtact tagtggcgtt
     1021 gttattcgcc aaatggtaga agcgattgct tttgaaagag gccattcctt agatgttaga
     1081 cgctatatgt ggcaaatgaa atattaatta ataggaggtt gcaaaagatg gcaaatcaat
     1141 tatttcacat tgtgattaca acacattcta ccctttgtga gggttattta aaggcaacaa
     1201 aattaatttt aatgaatgac gccacaggta ttagtgctgt tccatttaaa gaaaatacta
     1261 gtccagatga ttttgaggag agtatgaaag aaataattag tcagcatcat ttgcaacctc
     1321 taattatttt aacggattta attggaggaa cacctaataa tgtttctatt aaacagttga
     1381 acaacaatag aattcaaatt attgctggga ttaatttacc tcttttactg gagttattaa
     1441 tggcccagtc agctggtaaa tctatagaag aaatagattt taaggaatta ctgaataact
     1501 ctcaaaaaag tatggttcat attaattcgc ttttaaaaga tgtcagttaa ggtggcaatt
     1561 tctattctat aaattttaaa aattgaagga ggaaatagaa tgattaaatt agtgcgtgta
     1621 gaccacagat tacttcatgg acaagtaata ttttcttgga ctaaacagta tgatattaac
     1681 catattattg tggctgataa caaagttcca ggagatccaa tgtctgtgat ggctttgaca
     1741 attgctaaac ctgctgattg caaattagac attgttaaaa ttagtgatgt taaagggatt
     1801 atggaaacat ccccaaatga taattacatg attttaatta aaggacctaa ggaagctttt
     1861 gaattagttc aaaatttacc agaaattaaa gaaattaatt ttggcggtgt gtctaagaaa
     1921 agcgagtcca aacaatatgg aaaggcagtc tttttaactc ctgaagaatt agaagccaca
     1981 aaaaaaattc ttgatcaaga agtgaaaata tttgtgcaac aagtcccatc ttcaagtatt
     2041 gaaaatgtag attttagtaa gtaagggggg aaaataaatg ttattaaaag ccattttatt
     2101 aggtttagtt ggtgtggtag ctgttattga ctccaggtta attggtcgac aaaatattgg
     2161 tagaccacta attttgagta cacttgccgg acttgtgcta ggtgacttgc atacagggat
     2221 tgttcttggg gcatctttag aattaatttc tatgggattc gtctcaattg gggcggctgg
     2281 acctcctaat atgcaacttg gtagtattat tgccactgct tttgcaattt taactaatag
     2341 tagtacagaa acagccttaa caatagctat cccagtggct gtagctggtg aatttatgag
     2401 tattatcatg cgtatgataa ttgctcaatt tggacatgct gcagataaag ccattgaaaa
     2461 taataaattt agaaaagctc aaattattca tatttattgg tcatttattt ttaatgcttt
     2521 tgtttacttt attccaatct ttttaacagt atattttggt gctgacgttg tggcagattt
     2581 agtagataaa attccagaaa tgattacaga cgccttgact gtctctggaa atatgctttc
     2641 cgcattaggg tttgcaatgc tattaagcac aatgttgagt aaaaaattat atccttactt
     2701 tatttttgga ttctttattg ttgcctattc aggtctttca ctaattggcg tgacaatttt
     2761 tgcagctctg attgcctttg taatggatca agttaaatat ggaaaaagag aagaggcgca
     2821 tggttaatgg aaaatagtac agaaaaaaaa cgtttaatca caaaaaaaga tcttcataag
     2881 atgtgtcttc gttcatggac aatcatgtgt tcgtggaatt atgaaagaca aatgcatatg
     2941 ggatttatgt atgggatggc gccaatttta aataaagttt ataaaaatga tgaagagaaa
     3001 aaaagagaag cttatactcg tcatatggca ttttttaact gtacgcctca aatgactcca
     3061 tttattatgg gactttgtgc ttctatggaa gaacaaaatg ctcaagcaga agaaggaaac
     3121 tttaatactg aatctatctc catgattaaa accagtttaa tgggtccttt tgctggaatt
     3181 ggtgattcat ttttccaagg tactttaaga attattacat ttgggattgg attgtctttt
     3241 gctaagcaag gtagtatttt aggaccgatt ttagctgttg gcctttttgc tataccttct
     3301 attttagctg ttttttacgg cggtaaatta ggatatgagt ctggcaataa ataccttact
     3361 aaattgtatc aagaaggtct tatggatcga gtaatgcaat ttgcttctat cattggtttg
     3421 gctgtagtag gtggaatggt ggctagcatg gtgccaattg tcaccccttt aaaattcact
     3481 acagggggaa cagaacttgt tttacaagac ttacttgatt ccattattcc tggattatta
     3541 ccacttgtat gtactttggg aatatataaa ttgattaaga aaaatgttag tacaaatatg
     3601 ctcttattag gttgtatttt ggcagggttt gttttaagta taataggtat cttataatga
     3661 ttaaggctct aatttttgat atggacggag ttttaattga tagcgagatt atgtatcaaa
     3721 agtgggtatt taatttttta aaacaagaaa atttaagcta tcctttgtat tcttatcaaa
     3781 aaaagattgg aactacagca agtatttttg atgatataga aaagtacaat gagggatgta
     3841 acagtttaga attgaaggga aaatttacta aatattggaa atcgcaaaag attgattact
     3901 tggatatttt tcctaatata ctaattgaac agcttgaatg gttaaaaaag aaaaaaataa
     3961 aaatggcaat tgcttcttcc agtccaatgg atactataaa tgaagttgtt accacttgta
     4021 aaatagagtc atattttgat tgtttaatta gcggaagaga tttgccagaa agtaaaccta
     4081 atcctactat attccttaaa gcttcagaac agctcagaat tccagttgaa gaatgtctgg
     4141 tgatagaaga ttcttataat ggtataaaag ctggtaaaag agcaaatatg aaggttcttg
     4201 caattaaaga taaacgtttt tctcaagatg taagtctagc agatgatgtt atttacgata
     4261 ttaaatatct gcgacaagaa gtacaggtga aatttggaat ataaataagt tttttgatgt
     4321 atttagagaa tattagtaaa aataaaaatc atgcccaaat ctaatcaaaa ttgattgctt
     4381 tgggtatgat ttcttttaat atcaatctat tactttagga tctgaatcat ttttatgcac
     4441 cgtatctaaa gtgatatttt ctgtgacttc aataacataa ctaattctat cacaacgaac
     4501 tgtggattga gaataatgaa atggttgatt atttttatct ttgccaacct tttctaaaat
     4561 aaatagcgga tctcctacta tacattgcaa taagtcggaa agctcaggtg ttgcagataa
     4621 accgtttatt tccataatag agctcgtagc tttgacatca tagtcatctt ctagaagttt
     4681 atataatgaa gtatattggc tacctttttc aaataaagtt ggaaattttt cttctgatgc
     4741 gaaaaaatta tcaattccca tcggggcacc gtcttcccac attaaacgtt taatattgta
     4801 aactctatca gttacattga tttgtaattt attagctaaa aactcatcag cctttataat
     4861 tttagaatgt aaaacagtat atctaatttt atgtcctcgg gtagaaagag aatcgctaaa
     4921 tccatgaact ccagctaatt ttaaactttc ttttttttga gttacaaagg tccctttccc
     4981 ccttaatcgt tcaactgttc cactttctgt taaaagttta aaagcttttc gaatggtaat
     5041 cttacttact ccataaattt tacataattc ttcttctgta ggtaattgct ctcctggaag
     5101 atattttttt tcacgaatat cgttacgtat agaagcttct acttgtagat ataatggtct
     5161 attatcttga aaattcatag tacactccct aaaaagttat acttcattat atcacaattt
     5221 attaaaataa aagattaaga tataaatata aatgaactag tctttgacta accaatgccc
     5281 gcttttgaaa gaaaacaaat tcattctgtt ttaagtaaaa atccttatgt taccactcat
     5341 tctgaagggg atgagcctta tcgctacttg gttgtggaac caagcgataa gacaatttta
     5401 taaattcaat attaattaaa ataaaaacaa acaaagtaga ttattttact ttgtttgttt
     5461 ttttat
//
LOCUS       DACBZK010000119         5438 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.125, whole genome shotgun sequence.
ACCESSION   DACBZK010000119 DACBZK010000000
VERSION     DACBZK010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.125"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(65..286)
                     /locus_tag="IVD66_002635"
     CDS             complement(65..286)
                     /locus_tag="IVD66_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6146804.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYYRKKKVEFFTFLFLFFG"
     gene            734..3097
                     /locus_tag="IVD66_002636"
     CDS             734..3097
                     /locus_tag="IVD66_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HAP6146805.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKLGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRNDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFHSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAATLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            3465..4388
                     /gene="truB"
                     /locus_tag="IVD66_002637"
     CDS             3465..4388
                     /gene="truB"
                     /locus_tag="IVD66_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HAP6146806.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            4392..5333
                     /gene="ribF"
                     /locus_tag="IVD66_002638"
     CDS             4392..5333
                     /gene="ribF"
                     /locus_tag="IVD66_002638"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HAP6146807.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKKDEQATAEYFSQQ"
BASE COUNT         1900 a          938 c         1140 g         1460 t
ORIGIN      
        1 ttttttgttt tcattaagac gtattaccta agagttccat gactttagtc tggtagcgtg
       61 tcagctaacc aaaaaagaga aaaagaaaag taaaaaattc gactttcttt tttctatagt
      121 atataaattt ttgcatatag ataaagatca agataccgat aacggaagct agattgtaat
      181 ctattttagt gacagtcagg tatagccaag taactagaag atcagtggaa cctgcaccat
      241 aaaagtttga gtttgtcggt ccgttgacag ttaaaagaaa aatcacgttg aagttattga
      301 tatttccgat tacgccgctt cgatttggtc acgatccaaa ttttggataa tccctgtaga
      361 aattagcata gtagctggga taccaattca catattgaca aagataacag agacttttac
      421 ataaaacgga tcaatcagga aaggaattgc tcgatccagc cccagttttc caacaatgtg
      481 ttaactggcc tagcgtcatt cagcaaatta tgcatgatga ggagcgaaat gaactgcgga
      541 acagccattg tgataacgac aagttttttg gatcaatgta aaaaacgtca gcgaaaggaa
      601 aaatttcgtg gttttttata cctgttcatt tggctagata taaaatccaa acaaatgaac
      661 agaagtgctt attaggtttc aattgggagt atctgcgcta gaataagagt aataatgaaa
      721 aggagtgtta tgtatggatt attctagtaa agaatacttt gataaaatga cggcttggtg
      781 gcgtgctgct aattatcttt ctgttgggca actttatctt aaagataacc ccttactgag
      841 acgtacactg aaaccagaag atgtcaaaaa acatccaatc ggtcattggg gaacgattcc
      901 tggccaaaat tttatttatg tccatttgaa ccgagtcatc aataaatatg atttgaacat
      961 gttttatatc gaagggccag gacacggcgg acaagtcatg gtatcgaatg cttatttaga
     1021 tggaagttac acagagatct atccagaagt aacggaagat gagacaggaa tgcaaaaatt
     1081 attcaagcga ttttcatttc ctggaggcat tgcttctcat gcagcaccag aaacaccagg
     1141 ttctatccat gaaggcggag agcttggata ctctctttca catgcagtcg gagctgtatt
     1201 agacaatcct gaagtaatct ctgctgtcgt gattggtgat ggtgaagcag aaaccggtcc
     1261 tttagctgga agctggttct caaatgtctt tatcaatcca gtgatagatg gagctgtttt
     1321 accgatcctt catttaaatg gtgcaaaaat agccaaccca acgatcttgg cacgtaaatc
     1381 agatggagaa ttagcaaatt actttaacgg acttggctgg gagcctttct ttattgaagg
     1441 aaatgatcca gaaaaattaa atcctgttat ggctgaaaaa atggatcaag caatcgagaa
     1501 aatcaaatcc atccaaaaag aagctcgcct gaagacagca acagatgtcg tgatgccaaa
     1561 atggccagta ttgatcgtac gcacaccaaa aggatggacc ggtccaaaag aatgggacgg
     1621 ggaaccaatt gaaggaacct tccgagcaca ccaagtaccg attcctgtag atcaagaaca
     1681 tatggatcat gcagatgctt tactccgttg gctgaaatcc tatgaaccag aaaaattatt
     1741 tgatgcacaa ggacgtattt tagaagaaat cagagaaatt gcgcctactg gtgaccaaag
     1801 aatggcaaaa aatcctatca ccaatggtgg aatcgatcca agaccgctta ttatgccaga
     1861 ttggaaaaaa tatactttgc aatttgaaaa actaggctcc gttaaagcag aagatatgac
     1921 cgaacttggt aaattcgttc gcgagatcat tgagaaaaat ccagaaaatt tccgtatatt
     1981 tggaccagat gaaacaaaat caaaccgatt gaatcaagtt ttcaaaacga caaatcgcca
     2041 atggatggaa aaaatcgaac cagaaaatga tgaatggctt tcgccatctg gtcgcgtcat
     2101 cgacagtcaa ttatcggaac accaagatga agggttctta gaagggtacg ttctgactgg
     2161 acggcatggt ttttttgcaa gttacgaatc attcttgcga gtggttgact ctatgttgac
     2221 tcagcacttc aaatggatac ggaaatcaca tgacctttct tggcgaaatg attatccttc
     2281 gctaaatctc attgcaagct caacagtctt ccagcaagat cacaatggat atagccacca
     2341 agatccagga atattgacac atttggcaga aaagaaggcg gagttcatcc gtgaatatct
     2401 gcctgcggat gcaaatacat tgctcgcagt catggataaa gcattccact cgtcagaaaa
     2461 aatcaatttg atcatctctt ccaaacatcc gcgtgctcaa ttttactcag cagaagaagc
     2521 agccgtctta gtgaatgaag gcttgaaaat cattgattgg gcttcgacag caaaagagga
     2581 ggaacctgaa ttggtcattg ctgctgcagg aacggaatct aacttagaag cattagcagc
     2641 tgcaactttg ctgctggaag aattcccaaa actaaaaatt cggttcatta atgtcgtaga
     2701 tttattgaaa ttacgtcatc caagtcaaga tccgcgtggg ttgagcgatg aagaatttga
     2761 tcaatatttt acaaaagaca aaccgatctt atttgctttc cacggttatg aaacattggt
     2821 ccgcacgatt ttctttgatc gtcataacca tcatttaatg attcatggct acaaagaaaa
     2881 tggagatatc acgacaccat ttgacatgcg tgtagtaaat gaacttgatc gttatcattt
     2941 ggcaaaagac gcagctttaa aaatcaaagg aagtcaagca gaagattttg cggaaaaaat
     3001 ggatcagaaa ttacaagaac atcaaaacta tattcgtgaa aatggtattg atctgccaga
     3061 agtattggat tggaaatgga aaaatcttga tcaataaaat gataaaatcg atcccgcaaa
     3121 acagaatttt ttacattgat taagaaactg aaaaaataaa taaaaaaaac ggaaaaaaga
     3181 ctggaagaat ggacagtctt ttttttcgtt tttgggaagt gaaaaccaaa ctatttacct
     3241 gtaagccacc cataaatcca atcaaatggt gcaaagaaaa aatcttccat tctattccct
     3301 cctttaaaaa aacataacat gatttctatt tacgtgagca tgaattttgt tacgttttta
     3361 ttgccgaaaa ataaaaaccg ttcattatga tgtcaaattc gtcagtaatt gatgcaatgt
     3421 gttataataa ttcagttaaa tcaaaaatga aatggagaaa agacatggac gggttattac
     3481 ctttatggaa agaacgcgga atgacaagtc atgattgcgt attcaaatta agaaaaatct
     3541 tacatacgaa aaaaatcgga catgggggta cgcttgaccc agacgtagac ggtgtgttgc
     3601 ctatttgtat tggaaaagcc acaaaagtta tcgagtattt gacagattct gggaaaatct
     3661 atgtaggcga gataactcta ggtttcagta caacgacgga agatcgatcc ggagaacggg
     3721 tagaaacaaa accagtagat atgtctttat ctgaagaaaa aatagatgaa gtgatggctt
     3781 catttattgg tgagatcacc cagataccac caatgtactc agcggtaaaa gtcaacggta
     3841 agcggttata tgaatatgcc cgcaataatg aaacagtgga gcgtcctgtt agaaaggctc
     3901 agatttaccg ttttatccgg acaagtgaat tgacaagaga cgaagtgaca ggaaccattt
     3961 cttggcgctt cgaagtagaa tgcgggaaag gaacctatgt ccgcacatta gctgtagata
     4021 caggcaagaa acttggttac cctgcgcaca tgtctgatct gacccgaaca gcaagtgccg
     4081 gtatgtccca gaaagatgct ctgacattag aagaagtagc tcaagctgtg aaaaatggga
     4141 caatcgatga ttgtttgctg ccaatagaaa aaggagtgaa acgattcaaa cgagtagata
     4201 ttactgatga agtatggcag aaagtaaaaa acggtatgag acttgattat actgtatttg
     4261 cgctcccaga aatgccgtca gaagaaattg ctttgtttta taaaggcaaa gttgtcagta
     4321 tctatcagcc aaacccgaaa gaaaaaaaca aattaaaacc tagtaaagta ttgagaaatg
     4381 aggaataacg aatgaatatc atcaagatca gacatcctta ccaatcagaa caaattccag
     4441 aagacgatgt cgttttagta ctgggatttt ttgacggcgt gcatattgga caccagaaag
     4501 tcataaagac aggtatggaa attgcacaaa aagaaggatt gaaattagca ttgatgactt
     4561 tcaatcagca tccatcgatt gtctttaaaa agatcgatcc tagcagcgtg aaatatttga
     4621 ctagccttaa gcaaaaagaa gaaaaaatgg ccgctttggg tatagattat ttatatgaag
     4681 ttgattttac ttcttctttt gctcatttag caccgcagga atttgttgat caatacatcg
     4741 tagggttaca tgcaaaatat gctgtttccg gttttgatta tacgtatgga ccaaaagaca
     4801 ttgcagatgt cgctcatttt cctgaatatg ccaaaggaag attcaaaatc gtcacagttt
     4861 ctaaagaaga agaacaaggt gaaaaaatca gctctacccg tattcgagga ttactagaca
     4921 gcggacaagt aaaagaagca gcaaaactat taggttgcac atatgaggta gaaggggtag
     4981 ttgtccatgg cgatgcacga ggcagactac taggattccc tacagcaaat gtcaaagtaa
     5041 agagcacagt tcatttgcct aaagaaggtg tttatgtatc ggaaataaaa attggggaaa
     5101 cttggtatcc agccatgggt tcaattggac ataatgatac attcggtgaa ggacgggagc
     5161 tgactgtaga attgtatatt ttggacttta atcaagatat ctatggtgaa catgtcgcag
     5221 tacgctggaa tcaattttta agagatcaag tgaaattttc tagtgtagag gaattgattg
     5281 aacaactcaa aaaggatgaa caagcaacag ctgaatattt ttctcagcaa taaaacatta
     5341 tgcataaaat ctcttgttta tgtataacta gcaatttcaa taaaatgggt gataaataag
     5401 cccaggaaag gggctgtgac aaaagtcttg tcacagcc
//
LOCUS       DACBZK010000120         5427 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.126, whole genome shotgun sequence.
ACCESSION   DACBZK010000120 DACBZK010000000
VERSION     DACBZK010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.126"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(126..772)
                     /locus_tag="IVD66_002639"
                     /pseudo
     CDS             complement(126..772)
                     /locus_tag="IVD66_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FusB/FusC family EF-G-binding protein"
     gene            complement(1180..1683)
                     /locus_tag="IVD66_002640"
     CDS             complement(1180..1683)
                     /locus_tag="IVD66_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP6146808.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TELSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(1806..2570)
                     /locus_tag="IVD66_002641"
     CDS             complement(1806..2570)
                     /locus_tag="IVD66_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HAP6146809.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            2678..2953
                     /locus_tag="IVD66_002642"
     CDS             2678..2953
                     /locus_tag="IVD66_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HAP6146810.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            3391..4341
                     /gene="yidC"
                     /locus_tag="IVD66_002643"
     CDS             3391..4341
                     /gene="yidC"
                     /locus_tag="IVD66_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAP6146811.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     IDVTESAKPADSKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(4520..4720)
                     /locus_tag="IVD66_002644"
     CDS             complement(4520..4720)
                     /locus_tag="IVD66_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146812.1"
                     /translation="MGGISALSFMENGVLCGRATWAKGVAPFVTEGEEKASSWMLEEG
                     KQNIKELSTLLEETATPVYVDR"
BASE COUNT         1584 a         1135 c          943 g         1765 t
ORIGIN      
        1 aaaggggctg tccccagact ttagtaggcg tcattagcta tctttcgtta gcatttaaag
       61 gcgaacacca tcacctattc acttccatta aaagatagca tatttttctg taaaaaacaa
      121 taaaattatc gttctttctt tacacgttca gcaaattcat agaaaggagc caatttcgtt
      181 aactgttgat tacattggtc actatcatga caaatataat tccccttttt cgtatacgtg
      241 ccatcagaac ctgctttcgt tgtagaaaga aaaagcgaaa cattcgatgt tttctgacag
      301 attgcacaga ttcccttatt tatcgttggt gataaagtac cgctaatccc ttttaatttt
      361 tcatcttcgt aatagaccat gaattttttc tgcgtacctg gatcattcca gccgatgtac
      421 gtatgttctt gcaagtcgat ttcattccaa gctggttgtt tgagtttttt cacttttcgg
      481 aataatttct cgatttgtgg tttgctaggc tgcataaacg gctgaacgat ttgcttcagc
      541 tcctccaatg ctctttctgc ttgcgctttt gtcagtttta cgtctaaaac tgtcgttaaa
      601 aatgtatcga ttctggcagt tcgtgatcta atatgtctcg aatcttttca gctgctagtg
      661 cctgaactgt ttgtaccgtt tttggatcat tgacagatga gtacgcattt aataactgtt
      721 ctacttctct tattataaaa aaatattggt atggttttat tgtttgttcc atgattttaa
      781 agtcctttct tctaaccaaa gtgcatactt tgtagaaaaa agtgatcttc tgcaaagtat
      841 gtgttacctg aagatcccgg actcttttaa ataagatacg ttttgcatct tatcatcacc
      901 ccctttaatg cttattattc tatgtacatg attcattcga taaataaaag taaaccgtat
      961 cttgaacaga tagtcaactg caaacagaaa aaaggactgt gacaaaagtc gtgtcaaagt
     1021 cccttgtttc gaatgaatgg tgttcaaaag ctggcatctg cggtaataag ccgaaacttc
     1081 acaaaaattt gagaagcaat tttcgtaaat tccttcttat ttcttgaagc tgaccacttc
     1141 tgtcacaacc tcaatatggt ctattattgg ttttatctat taaatcgagg attctttccc
     1201 aaagtaacgt tgccatctct tacgcatact tgctgacata ggctgagcgg cttctttgac
     1261 tgcgcagtat ttgtctacga atgttacgat atatccttct ttgtacttag gcggtgcaat
     1321 cgttgcgccc cacatgtgct tcaaaatgat atctcgctca agatccgaca attcggtgat
     1381 cttttctgca ttctttacag caattcttgg atggatatac gcatgtgtgc cttcatcaaa
     1441 tttcgtcgta cgccaatcat agtagaacag atcatgcaaa agtccagcac gcgctgttgc
     1501 tttagcattg ccaccccatt tttttgcgag cagataacta tagtaagaaa cactgatgga
     1561 atgctccaaa cgagtggaat gaacatgctg tgtgtaattc gctaattttt tcactgcttc
     1621 tgtttctaaa agatcttcta cataagacat atattcttcg tcttcacgcc atttttctgt
     1681 cataattatc gatctgccac ctttttgaat ttcattttct tctgaaattg atctaagtat
     1741 accaccagtg ttcggattat tctagtcgcc ttggataaaa tagccaaagc ttaatagttc
     1801 cttaatcata aagaaaaatg ataaagaaca atccctgccg caaccccaac attcaacgat
     1861 tccgcatttc ctttcatcgg gatatatacg ttctgatcag tcaaagacaa gatttcctga
     1921 cttaccccct gaccttcgtt ccccatgatt attgcgaagt tatctgattt ttctactttg
     1981 tctaatgcgt gtgcttcttc atttaattct gtgccataca ctgtaaaccc tttgtctttc
     2041 attaaaggaa tcacttctgt caaatctttt tgcaacacag gcaaatgata attgcttccc
     2101 tgcatgctgc gcagcacctt tgtactataa atatctgccg ttcctttgcc taataaaaca
     2161 ccagccatat caaatgcatc tgccgtacgg atcatcgtcc ctacatttcc aggatcttgt
     2221 acattatcta acaacagcca tcctcctgaa aaatctggcg tgccttcagc cgttaacgcc
     2281 atcactgcta agattccttg tggtgtaggt agatccgata cagcatccat gacctcatcc
     2341 gaaactagaa aagtagaaat ctctttgttt gcggccagcc agtctcccca ttctttcatg
     2401 cctcgctgtg tcacaaaaag ttcttttatt tctgcatcag acgacgcagc ttcttcaatc
     2461 agatggaacc cttccaaaag atattcttcc ttttcttccc gatatttctt tttatgtagt
     2521 ttttttaatt ctttgattct tggatttttt gctgattgga tctctttcac attcctcacc
     2581 tccccatgat tatatcatgg aataggtgct tgagcttgtt tcatcctaaa aaaatcggta
     2641 tcattaattt ataaaatagg aaagaaaggt gacgaacatg cgcaaagtta aaatgaacgt
     2701 ccaaggacgc gtccaaggcg taggatttcg ctacatgacc aagatggtcg ctgatcaact
     2761 aggcgtgact ggaacggtaa aaaacgaaga tgacggctca gtcacgatcg aagcaatcgg
     2821 caatgacgac atcatccaga aatttattga agaagtcaag aaatctccga gcccaagtgg
     2881 acgagtgcag tatgtggatg tccaagaaga cccgatgatt gaggaacgaa agaaatttga
     2941 tgtggtggga taaggttgtg aaaaagctgg tctgcatcaa gcattaagga caggttgtga
     3001 aaaatagctc tccatatttt tcaacaggct ggacttaatg ccgtagatgc aagcttttga
     3061 acaccgtcga taaggttatt cttgaggcgc tttgcctcaa aaattaagga cagcagtgaa
     3121 aaagctgatc tatcacttgc agtgagttca tttgactccg ctttttcggg cagaaaaaaa
     3181 gtttttagtt tattaaagta agaaagaaac acttggaatc attctacttt ttcctagtat
     3241 ttctttcttg attttttgtc tttttttcaa aatttttcgc tacgtaaaag aacgaatatt
     3301 tatatgaaat ttctatgaag ttgattgaat tccatgcgct tttttagtat agttaagttt
     3361 gtgtaaaaat tatagaagag gaagtattct atgaataaat ggaaaaactg gttattggga
     3421 tccggacttg tcagtatcct gctcttttta tctggctgtg tgcggatgga ttcaaacgga
     3481 aaccctgaca cttcgggaat cgtttatcga gtactcgtcc atcctatggg ccaagcgatt
     3541 acatatctag ttgaaaattt caattggtct tatggctggg cagttattgc aatgactgtg
     3601 atcgtccgta tcatcatctt gccactaggt attagtcaat cgaaaaaaac aatgatccaa
     3661 tctgaaaaaa tgcaagcgtt aaaaccacaa gttgaagcag cccaacaaaa attgaaagct
     3721 gcaacaacac gtgaagaaca aatggcagca caagcagaaa tgcagcaagt ataccgcgaa
     3781 aacggattga gtatgaccgg cggaatcggc tgtctgcctc tattgatcca aatgccgatc
     3841 ttctctgcct tgtactttac ggcacgttat acagaaggta tccgggaatc atctttctac
     3901 ggcatcgatt taggctcacc aagtatggta cttgttgcca ttgcaggggt cgcttatctg
     3961 cttcaaggat acatctcaac gatcggtatt cctgaagaac agaaaaagac gatgcgtacg
     4021 atgctgatcg tctctcctgc tatgatcgtc ttcatgtcga tcagtgcgcc agccggtgtt
     4081 acactttact gggtagtcgg tggtgtgttc agctgtctgc aaacattcat cacaaacgtt
     4141 atgatgaaac cacgtttgaa agcacaagtg gcagaagagt tgaaacaaaa cccaccaaaa
     4201 caagtcgtca ctccaagaat tgatgtgaca gaatcagcta aaccagctga cagcaaacaa
     4261 gcaaccaaac aaatcaagca acccaaaaac agtacaaaca ataaaggccg caacgcagga
     4321 aagcagcaga agcggaagta gatagtaaat aagagtgtaa taaaaattca ttaacagttt
     4381 tagcaattaa aaatatcgac caagattttt gaaaaagaaa tctggtcgat atttttattt
     4441 aagtgaatgt ttaatttgaa tcatcgattg atcgctatct aattgcagca gcatcttttt
     4501 atgaagaaac aactttttct tatctatcaa cgtagacagg tgttgctgtt tcttctaata
     4561 gtgtacttaa ttccttaata ttttgttttc cttcttctaa catccaacta ctcgcttttt
     4621 cttcgccttc ggtaacaaaa ggcgccactc ccttcgccca tgttgctcgc ccacataaga
     4681 caccattctc cataaaggac aacgcggaga taccacccat ctaaataaca tccataaacc
     4741 tttctagtag aagaatagtg atagtatcca tccctttttc tactgggaat acaattacac
     4801 gattcaaagc ttgatacaca acatttccct tcttataaac cgctattgta accgaattgt
     4861 tttgaatcac ctttttggga tagaaactgg ctcctttccg caacttctta aatgttggtt
     4921 tcttttatac tttctttgta gcaactacaa atttcttcaa atctctaaat gtttgcataa
     4981 caaccgcctt tctgactttt actcaggatg gtatttaaaa atcagcaaaa taaggcttct
     5041 ctccatcttt tttatttcct agctgcttta aagacactct tgctgttttt taatctctat
     5101 caagggggct ctgaatctat tttgatgaac ttatcttatt aatttctcaa atgagctgtc
     5161 agacacaact gtattttttc aatctcatac cggacaacta tgccagctta aaaaaatttc
     5221 ctctggcaaa acttctttat tgaaaaatga caatgaaaaa agaccattct ttttgttgaa
     5281 tgctcattgt gtaaacatat ttcctgcgac tgctcttcga accattctca gtgcaatccc
     5341 taatttatct attaaatctt cttttagttc ctcatctttc atattcaaaa tttcctttgt
     5401 atgttacaca agtttgttct ctaaata
//
LOCUS       DACBZK010000121         5247 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.127, whole genome shotgun sequence.
ACCESSION   DACBZK010000121 DACBZK010000000
VERSION     DACBZK010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.127"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(207..1169)
                     /locus_tag="IVD66_002645"
     CDS             complement(207..1169)
                     /locus_tag="IVD66_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6146813.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="IVD66_002646"
     CDS             complement(1171..2610)
                     /locus_tag="IVD66_002646"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HAP6146814.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="IVD66_002647"
     CDS             2795..4741
                     /locus_tag="IVD66_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HAP6146815.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKINGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5005..>5247
                     /locus_tag="IVD66_002648"
     CDS             5005..>5247
                     /locus_tag="IVD66_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP6146816.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPK"
BASE COUNT         1697 a          888 c          867 g         1795 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaagc acatttaaaa ttaatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatttg agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta
     4861 ttagaatttt aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca
     4921 tgttactaaa taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat
     4981 tctaaaataa agggagaaat gtctatgcta tacggtgcaa ttgaagcagg cggcacaaaa
     5041 tttgtgtgtg ccattggcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca
     5101 acgacacctg aggaaacaat gcctttagtc attgacttct tcaaacaata ccaagcagat
     5161 ttagcaggga ttgggattgg ctcatttggg cctatcgata tccatcgcga ttccgccact
     5221 tatgggtaca ttacctcgac cccgaaa
//
LOCUS       DACBZK010000122         5212 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.128, whole genome shotgun sequence.
ACCESSION   DACBZK010000122 DACBZK010000000
VERSION     DACBZK010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5212
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.128"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            604..954
                     /locus_tag="IVD66_002649"
                     /pseudo
     CDS             604..954
                     /locus_tag="IVD66_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
     gene            948..1370
                     /locus_tag="IVD66_002650"
     CDS             948..1370
                     /locus_tag="IVD66_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146817.1"
                     /translation="MVNKPIALVMGLVLVLFLTSCSKKQEIQKTNLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2540..3508
                     /locus_tag="IVD66_002651"
     CDS             2540..3508
                     /locus_tag="IVD66_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAP6146818.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKSDIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKAPTSLQEKIKEQKRKLELL
                     QQLEKLEREQNTQNKENNAQKSEINSDIPSELKKDLLDNLQNLFKD"
     gene            3525..4049
                     /locus_tag="IVD66_002652"
     CDS             3525..4049
                     /locus_tag="IVD66_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAP6146819.1"
                     /translation="MTEKTIKELAEELGVSKTAINKKVSDENRKLWFSKIGNKFVINE
                     TGQKAIKSMFFNENENSNQQLVGEKTKTETHKNANQVPELEVLSLLEQQLNQKDMQLQ
                     EKDEQIKQMQKLLDHQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIE
                     KQSKTEKKWWQFWQ"
     gene            4425..4706
                     /locus_tag="IVD66_002653"
     CDS             4425..4706
                     /locus_tag="IVD66_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146820.1"
                     /translation="MDILVRNINPKIIARIDKRCQELTTKTGKKWSRNKYLKVLIESD
                     FDRQLMNYKKDQFDLLLEKFIAIQTENTNILNDYVHTNNQLIETLIGGI"
     gene            4708..5124
                     /locus_tag="IVD66_002654"
     CDS             4708..5124
                     /locus_tag="IVD66_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146821.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
BASE COUNT         1972 a          894 c          867 g         1479 t
ORIGIN      
        1 aaaaaaaaga aaaatccgct tatgcaactt cttctttttg tattttgggg cgctacccca
       61 atccccaagt atcggttatt taatagcgcg gaaatccaaa gaataggacg taccctgaaa
      121 caaaaaaaga ctgctctcac gagcagccca aaatgagatt atcctattca tcaacataaa
      181 aatattacaa agtgaagaac tagagaaaga caaaaaaagc atatcaaatc ctctcaaaaa
      241 taacaagtct ttaaaaaatg acagataaaa atgcacaaag aactaaaaaa gagaaatcgc
      301 gtaaaatcaa gcattagaag ctagtaacta gctagaccaa ttaaaaatca caaagtgagc
      361 gtctctatcc attggtagag gggctacttg gcatagtgta cattatgtta actagctcga
      421 taaataacga ttatgttccc aaaacaatat tttatgaact ataacaaaaa tttgttatcg
      481 catattgtat attttaatta tataattata ggtgtatacc acttaaattt aacacaaagg
      541 cgtggttatt ttgaaaccca aaaagaaaat ttatctaggt ctcctctttt ccttgatgat
      601 tggaatagtc aaattgaatc aaaaagtctt aatcaagatc aaataataaa atatgcaaat
      661 tactgtggtg tttatcctaa aaaagtagca cgaatactaa acctttcaga ggtccaaaca
      721 caactaagaa aaggaaatgc catttatatg ggaactgctg gttatggaaa ttatagtaac
      781 agccgtcatg cacttgcatt atttgggtgg gtcaatcaag gtggttatca aacttactat
      841 gtgtggaatc cttggtataa ctacccaact gtaataagtg caaatgcagg accagttaca
      901 attcctgtac ctggaggtgg ttttacttgg gacaatacca ttacaaattg gtaaataaac
      961 ccattgcttt agttatgggt ctagtgttag ttcttttctt aactagttgt tcaaaaaaac
     1021 aagaaataca aaagactaat ctgattcctt ttctaggaac ttggcaaact aaagatcatt
     1081 cagaacgtct agtaatcact aatttaaata cttcaaaaaa tatagaacaa tataccatct
     1141 tagtaaaaga gaacaatcat aaaattcaaa tcattgataa aaatttaaat ataaatgaac
     1201 aagttttcat ttacaaagca acaaataatt tactaacact gcgctctaat aaaaaacaat
     1261 tagattacac ttttagtttg gattctccaa aaaagctcgt atttattttg acaacgaatg
     1321 atgggacaga agggacagct aaaccaattg aattttttaa agctgattga tgaatagttg
     1381 tttgatatta caaaacaata atttcaccga aggtgaaaca agcgaaactt tacaaaaagt
     1441 ggctagcatt tgctagcctt ttttgtattg tggagcgtgg tttttgaggg ggattcaagg
     1501 gggagcttgc gcccctttga caagcggtta tttgcaccaa atacgtaggt atttggctag
     1561 caaatataga gcttgccaaa cactttagtg agttttgtag aaagtacctt taaaggtact
     1621 ttcacattac gaacgatacg tccgtaggac gtactgaaag ggtgggattt atgagcgaac
     1681 taatgcaaaa tttggctagc aaaaaaagtt aaaaaatata tgctaataat cgagcgaaat
     1741 gaacactttt tcaagtgagc gaatccgcca tgacaaagct gaagcagttt atttcagctt
     1801 tgtcatggcg tgtgcctaga cttttaaaaa agtcggcaca cgagcaaata tctttatcaa
     1861 gctctaattt gcgttttaag acgtttgaaa cgtctaagta tataaatata taagagtagg
     1921 tttaagagtg cttaaatcga attttagagg gcattcagac aactttaggg ttgttagggc
     1981 ttgccctgac cgcctgtaag gcgctttaag aacaagataa gggatttata ctaagactgt
     2041 cttaaaacgt ctcaaacgaa ggctcatagc ttctcaaaga gttccttatg aacattttta
     2101 gcaaaggagc cggaagcgac tgcgcagtat aatgtgagag cagagcgatc acaccttttt
     2161 aagcgactgt agggagtaag attcccagtt gagaaaaatg cgcgaatctg tttggagaaa
     2221 aaagaagtgg ttttttaggc gggaaatttt gtccccctct tttataatct ctttttaaac
     2281 ctctttttaa acctctttac cgtcggctat atccttactc tcccaaggga atgacgcttt
     2341 tatctacatc gttttgtctg tttatctaca tcgttttgtc tgtttatcta catcgttttg
     2401 tctgtttatc tacatcgttt tgtctgtttg tacattgaat tagtacatcg acgatgttaa
     2461 tataagatgt agataaacag gcattttgta tttcataacg tgtatctctt gtgcgagtaa
     2521 gaaaggagct attttaaata tgtctaatga aatcgtaaag tatcatcatg aattaaatac
     2581 aattccgttg cgaaaattta caccagtcga aatgaatttg ttcttttcta tcgtatcaag
     2641 aatgcgtgat gtaggtgata aaaaagtaca atttacattc gagcaattaa aagatttaag
     2701 caattataaa gcaactgcaa atgttcgatt catagatgat ttagaaacaa cgtatgacaa
     2761 attaatggat ttacgttttg gtagaagaag tgctgacggt ttgcaacgtg aacgttttgt
     2821 tttatttaat caatttaaaa tcgacggaaa atctgatatt ccttttgctg aaatacaagt
     2881 tcatgaaaaa gccttaccct tacttaataa tcttgaagaa tgggtgcgct attctctcca
     2941 acaattcaat gaattagaaa gcagttattc aaaaacaatg tttcgattac taaaacaata
     3001 cagaaccaaa ggtttcgctt atttttcaaa agaagacttt catgaattac ttgatattcc
     3061 taaaagttac aaccaaggta cgattgatca acgtgtgttc aatccaatac gacaagaact
     3121 aaccgcaatc tttaaaggtt taacaatcaa aaagaaatac ggaaaaggac ggggaaagcc
     3181 tgtcattggc tatcaattta catttaaacc tgagataaaa aaatcagacg actttaacaa
     3241 acatgcccca acaaaagaag aacaaaacaa agcattagaa ctagctaacc aacaagttca
     3301 atctgaaaaa gcacctactt cattacaaga aaaaatcaaa gaacaaaagc gaaaattgga
     3361 acttttacaa cagttagaaa agttagaaag agaacaaaat acccaaaata aagaaaataa
     3421 tgcacaaaaa tcagagataa attccgatat tccttcagaa ctaaaaaaag acttattaga
     3481 caatcttcaa aacttattca aagattgagg ggtttttaga ttttatgaca gaaaaaacaa
     3541 tcaaagaact tgctgaagaa ttaggagtta gtaaaacagc aattaacaaa aaagtttctg
     3601 acgaaaatcg aaaactttgg ttttcgaaaa tcggaaacaa gtttgtgatt aatgaaaccg
     3661 gacaaaaggc tataaaatca atgtttttta acgaaaacga aaactcaaat caacaactag
     3721 ttggcgaaaa aacgaaaacc gaaacccaca aaaacgccaa ccaagttccc gaattagaag
     3781 tcctttctct cctagaacaa cagttaaatc aaaaagatat gcaactacaa gaaaaagacg
     3841 agcaaataaa acaaatgcaa aaattactcg accaccaaca acaactcacc ctgcaagcca
     3901 accaacaaat cgagaaactg caggaacaac tacagttgac ttatacggaa gaatcttcgg
     3961 aaaataaatc aacgactctt tctgaagaaa cagaatcgat agaaaaacaa tcaaagacgg
     4021 agaaaaaatg gtggcaattc tggcaataaa accagcaatt taaattaata aaaattgctg
     4081 gttttattct tctttttgct tttgcgagca gagcaacatg gacccatgtt gcgatatttt
     4141 ggtggcgccc caatccccgt tttttcgttg aatcttactc ggactgcact cgttttacag
     4201 ctgatttttc tgaattttga aagagcataa ggaaacgtgg tatcactttc ttacgaaagg
     4261 tgctagatag gctgtgccta tcacgtttct cagaaaaaaa tttgctatca cttttttgcc
     4321 attgtggcta ggctatgtat agtgttttgg cgaaaaatag ctatacaaat actatatttg
     4381 tatggtatac ataaattata cgctgatacg aaaggaaaat ttccatggac attttagttc
     4441 gaaatatcaa tcccaaaatt attgcaagaa tagataaacg ttgtcaggaa ctcacaacca
     4501 aaacgggcaa aaaatggagt cgaaataaat atctaaaagt tctaatcgaa agtgattttg
     4561 accgtcaact tatgaattac aaaaaagatc aattcgattt attactcgaa aaatttattg
     4621 ccattcaaac agaaaatacg aacatactga atgactatgt tcacacaaac aaccaactca
     4681 ttgaaacact tatcggagga atataacatg agaaaaactt ctgttcaaaa acacgtaacc
     4741 ctttatccca gtcacgttga cgttttagat tccatcatcg aaaaaaatcc agacgtcaac
     4801 aattattcag aagccattcg ttttttatgt atgagttatg aacctgatac caatacaacc
     4861 acaaccagta accaagcaaa actcaatgcc atgggaaaag aaatttctat catgacagaa
     4921 atcatggcag aatttgctga tttatatcta aaagatactg gtgttcttat cggtacaaat
     4981 tctaaagtgt atcaagaagt gaaagaaaaa attgaaaatc aactcaatcc ttcccgacga
     5041 aatcaaccca aaaatcgtca aaaagaaacc aatcaaacct ttacttctgg aaattttgac
     5101 ccaacaaact ttctaaaaag ataaaaaaag aaaccgatcc ctaaaaaaat tcctcgattt
     5161 ctttttaggg atcagtcttc cagcaagatt tgcaagttgg taccaacttg cg
//
LOCUS       DACBZK010000123         5199 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.129, whole genome shotgun sequence.
ACCESSION   DACBZK010000123 DACBZK010000000
VERSION     DACBZK010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.129"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(260..823)
                     /locus_tag="IVD66_002655"
     CDS             complement(260..823)
                     /locus_tag="IVD66_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146822.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            complement(810..1337)
                     /locus_tag="IVD66_002656"
     CDS             complement(810..1337)
                     /locus_tag="IVD66_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146823.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEAEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSEKEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            complement(1360..2697)
                     /locus_tag="IVD66_002657"
     CDS             complement(1360..2697)
                     /locus_tag="IVD66_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAP6146824.1"
                     /translation="MLMVQFTGIAMSVITINPQVIHADGIATYDAQFNCTTEGSGSGT
                     DSDGNDTGSGAVTGDVAKNIEDIYKYMNGEYGLSGASIAGILGNWKQESGIDPRAVEG
                     YYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVDWSKKNNGGSWWTTEAQLDFMF
                     KGDGGFVGILKDYALNASDDVVENAVTFHKNWEISADSESAVIAVRGENAKEIWKYMK
                     SKGMDGAKDESKINKISGGSSTGDGSNNSSSSASGTVEDACATTDDANSGSGSIGKEG
                     KINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFNGIYQGQCTELTWAYMS
                     QLYDGNQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDGWLWAVGDAGHTGVVIA
                     VFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGKAKFEIEK"
     gene            2817..3296
                     /locus_tag="IVD66_002658"
     CDS             2817..3296
                     /locus_tag="IVD66_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146825.1"
                     /translation="MTDKTSDLPKLAPKTSRVKSKKDGKTKNAVKKKSVKETSSLLLD
                     IPMSSFDDNTDETSVKIATHVGMNNQNDSFYNLLNSLRELEDKKNQVIASKAPDLTTD
                     LDAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            3756..5144
                     /gene="ltrA"
                     /locus_tag="IVD66_002659"
     CDS             3756..5144
                     /gene="ltrA"
                     /locus_tag="IVD66_002659"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP6146826.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
BASE COUNT         1634 a         1050 c          905 g         1610 t
ORIGIN      
        1 tgtctttaat agttttattt gactttttaa gaaagtattt acttttgact ttttttacgt
       61 tttacaacat atacgtattg taatgttcag ctcaatttat tataatctaa atgaattgat
      121 taataaaaat tctgaggttc gggtttttta tcaattcttt tctgtttgtg tttgtgatga
      181 aacaatcctt tttcggtagg ttttgttatc atcgtcagca caaagagcta acgttggtac
      241 cgttagctct ttttttattt tactctgctc ttacatagct atctaaatcc tccaaataaa
      301 acaattgatt ttctcctatg cttgttactc cacgccaaat tgttgttgtt gctgttgttg
      361 gagtatttct tgtctgtgta atcaattcaa ccattttacc tttttgattt gttgtatagt
      421 aatcagcagt atagctagat attggactat taccagtgcc taccatcgtg ccagaaatat
      481 caacaggact agactttact atctgaggaa attctttttg tatttccttc atattcttcg
      541 tatatttttc ccatgaattc cagttgtaaa ataaattaaa gaatttccta ctttgttcct
      601 taatttcagc atttcccaat tctttgtatt gagcttcctg catagctttc actttctggt
      661 tattcttgac tacttcgatt tgtttacttt taaggtcttc caattctttg acattattat
      721 cataagcatt tttcttttga aatagtacca cacaacaaag gatcacaatt atggaaagta
      781 ttccgatcgc ctttttagca gtagtgattt catgattttg cataaaaagc acccccagtc
      841 actttcttat cattatttag tgtgatggtt aatgtggtat catacacttt ttttccattg
      901 tattgaactt caaaatcggt caatgcttca tacaacccac tactagatgt cttaattcca
      961 aagtttgtta gcttaaaagt aaaaggctta tagtactcga ttttttcttt ctcactactc
     1021 ttatcagtaa ttggtggttt acctgttaca ataaatagtt ttctcaaaaa ttcttcacct
     1081 gattgatctg caaacttatt ttgaactgat ccattcaaca tttcttgaat atcattttct
     1141 aaatctttcc gtaatccatc cacctcattt ggtttaacct ctttaaagaa tgtcagctta
     1201 tcttcaatat gcacactgtg tttttcagct tctatgtcct gattctgctt attgaagaat
     1261 aggattccaa caagcagtgc taataacata ccagaaagca aagaaatgat aattgtatct
     1321 ttcactttac tattcatcta tatcgtcctt cattccaatt tatttttcga tttcaaattt
     1381 agcttttcct acaccgctaa agaaatgcac attatctgat ccgtccactc catcaatcaa
     1441 cgttaccgaa actccccttg ttggagcttg ggttggtgga acattaaagt tagcacatag
     1501 aaatgatcca tcttcaaaca ccgctataac tacaccagta tgacctgcat ctccaacagc
     1561 ccataaccat ccatccgaag cactaaaccc ataacctacg attggtttgt tcgttatttt
     1621 tgctcctgcc gatttgtagc tttcccatac atagccacca tttccagtag tcggttgatt
     1681 cccatcgtat aattggctca tataagccca cgtcaactct gtacactgac cttgatatat
     1741 tccgttaaaa ggtgaagttg accaatctgg ttctttgaat tttggtagcg tgatcgcttt
     1801 cccatatttt ttcaaagctt cttcataagt catattcgct attacttgac cttttttacc
     1861 gttaattttt ccttctttcc caattgatcc agaaccagaa ttagcgtcat ccgtagttgc
     1921 acaggcatct tctactgttc ctgatgctga acttgatgaa ttattcgatc catctccggt
     1981 acttgaacct ccggatattt tattgatctt actttcatct tttgcaccgt ccataccctt
     2041 gcttttcatg tacttccaga tttcttttgc attttcacca cgtacagcta ttacagctga
     2101 ttcggaatca gctgaaattt cccagttttt atgaaaagtt actgcatttt ctacgacatc
     2161 atcagaagca tttaaagcat aatcttttaa tattcctacg aatcccccat cacctttgaa
     2221 cataaagtcc aattgggctt ctgtagtcca ccaagaaccg ccattatttt tcttagacca
     2281 atcaactaat gctgtatgtc gcccagctgt ccattgacca tagccaatac ccatcagacc
     2341 atcagtaaat tgtttgatga agtcaacttc tctctgtcca tctccgtaat acccttctac
     2401 tgctcgagga tcaatacctg attcttgttt ccagttacct aaaatacctg caatactagc
     2461 acctgataag ccatattctc cattcatgta tttgtaaata tcttcaatat ttttggctac
     2521 atcacctgtt acagcgccac ttccagtatc gtttccatcg ctatctgttc ctgacccact
     2581 accttcagta gtacagttaa attgtgcatc ataagtagct atcccatcag catgtatcac
     2641 ttgcggattt attgtgatta cactcattgc aatccctgta aattgcacca ttaacataag
     2701 caacgtggca atctttctct tagatttttt caataactac gcccccaaaa agtgtacttt
     2761 tttatgttat tatgataata taataacata aattaataga aaggaaaagc taataaatga
     2821 ctgataaaac aagtgattta cctaaactag ctccaaaaac atctcgagta aagagcaaaa
     2881 aagatggaaa aacaaaaaat gctgtaaaga aaaagtcagt aaaagaaaca tcctcgttac
     2941 tacttgatat tccaatgagt tcttttgatg acaatacgga cgaaacttct gttaaaattg
     3001 caactcacgt tggaatgaac aatcaaaatg attcttttta caacttgtta aacagcctaa
     3061 gagagttgga agataaaaaa aatcaggtaa tcgcatcaaa agctcctgat ctcacaaccg
     3121 atttggatgc tgaaattatc caaatcaaac aagatgagcg atcagttaaa tcgctactga
     3181 aaacctactt tgatggtttt gataaagaac tagctcctta tagccaagca atcctaacta
     3241 aaccaataca agctccacat atttcaattt ccctacaaaa aaagagtgat gattaaacaa
     3301 tcattactct ttttttagat gtgcgccctg catgggtgaa aacttggtgg tgaaagtcca
     3361 ctacaggctt ggcagtagga actgttagcg aaagacaagg cggcaatcgt gaggttgtgg
     3421 ctgaaggaag tcggacgcaa actcctgaac tgacgaacag aaactagata caaggctgaa
     3481 ttaggtcgga taagtcttca tcacaagaca aagtccaata ctgcccgaaa cctatacagt
     3541 aaatctagca gttacatggg aggaaagttt tcactcttac cgggggagat ctcatgaggg
     3601 tgttgtgggc gttgaatgaa aacaaaccag cacaacgatc atggcgacat gatggtgaat
     3661 catgagaagt cagccgaggt catagtagta acgacactga ccgttacgaa ggactgaaca
     3721 ataagaatct tgaataattt aggaggtgtg agaagatgcg acgaccgcag aaaacaagaa
     3781 aacttggcta tcatcaaaga gctagtgtgg aacacgaagg gtatgatgaa gtgcgcagca
     3841 cttcttgcgg tgaacagagg aaacaagatg gtgtagaaaa tctgtttggg agaattctag
     3901 atcggaataa tctcaatcaa gcgtatcttc aagtagtcag aaataaaggg gcggctggtg
     3961 cagatgggat gaccgtcgat caactgcttc cttacttgaa agagcaccgc gaggaattac
     4021 tatccaattt acgccaaggg aactataaac ctcagcctgt tttgcgagta gaaataccga
     4081 aaccaaacgg cggtgtaaga aaactaggaa ttcccacggt tattgatcgt atgcttcaac
     4141 aggcaatcaa tcaagtgtta caaccgctat ttgaaccaga attctcagat aatagttatg
     4201 ggtttcgccc aaatcgcagc gcacatgacg cagtgaagaa agcaaaatct tattatgaac
     4261 aaggttaccg atatgtggtg gacattgata tgaaagccta ctttgacacc gtaaatcacg
     4321 ataagctgat gtatttcatt gagcggaaag taaaggacaa acaagtccta aaactgatcc
     4381 gtcaatactt aatgagtggt gtaatggaaa atggactcat cacaacaact gaagaaggaa
     4441 cgccccaagg aggcaatctc tctcccctgt taagtaacat ctacctgaac gaatttgatc
     4501 aagtgctaga aaatctagga cataaatttg ttcgatacgc cgatgactgc aatatctatg
     4561 ttagaagcaa acgagcagga cagcgtgtga tgaagaaatc cattcaattt ctcgaagaac
     4621 aactaaagtt gacggtaaat cgagaaaaga gtgcggtagg aagtccattg aaacgaaagt
     4681 ttcttggatt ctgcattctg ccaacaaaga aaggtattaa aattcgccct cacgcaaaag
     4741 caaaacagcg tgtgaaaagc aagctcaaac aactcactaa aagaaaccgt ggaagaagta
     4801 tccaacttat tttaaaagaa atcaagcaac taatgactgg ttggatcaac tactatggaa
     4861 ttggtgagat gaaagaattc atgagggagt taaacggttg gttgaagcga agaatcagac
     4921 aatatatttg gaaacaatgg aagaatccaa gaaccaaaag aaaaaatctg attcgtttag
     4981 ggatcgataa agcgaaagcg tatgaatggt caaatacaag aaaaggtatt tggtcagtct
     5041 ccaaaagtca tattcttcat cgatcattaa cagacaaaga actggcccgc caaggatatg
     5101 aggacatctc cttgaagtac cagttcgtac actcaactta ttgaaccgcc gtatacgggt
     5161 ccgtacgtac ggtggtgtga gaggggcgga aggtcagtt
//
LOCUS       DACBZK010000124         4933 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.130, whole genome shotgun sequence.
ACCESSION   DACBZK010000124 DACBZK010000000
VERSION     DACBZK010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.130"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            119..712
                     /locus_tag="IVD66_002660"
     CDS             119..712
                     /locus_tag="IVD66_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6146827.1"
                     /translation="MKDKIQCIFDKHNGNLSLKDARSEGLSPMTLDRLAEKDKIEKVA
                     PGFYTLKDAFVDELYLAQSIYSRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     KLDQYAIQPHYTNKENFDLGVTETESFYGNKILVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMDILKSPKEMTLYMLPLY"
     gene            728..1627
                     /locus_tag="IVD66_002661"
     CDS             728..1627
                     /locus_tag="IVD66_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAP6146828.1"
                     /translation="MTPTQFKEKTRNFAAEKHLNPQIVQRYYMMEKLLECIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTANPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAYLENARVPFKLDITSGDSIIPAALMYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGKDNSRMKDFYDLYMIPKLERIDEKNLYKSVQGTFKE
                     RNNQSVFKHLYDQEMPQLVKDEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEKAERKQNFKRSQQMNQEMER"
     gene            1630..2115
                     /gene="ssb"
                     /locus_tag="IVD66_002662"
     CDS             1630..2115
                     /gene="ssb"
                     /locus_tag="IVD66_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP6146829.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFSLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRMHADQSSSSPSPTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            2481..2741
                     /locus_tag="IVD66_002663"
     CDS             2481..2741
                     /locus_tag="IVD66_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146830.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            3182..3388
                     /locus_tag="IVD66_002664"
     CDS             3182..3388
                     /locus_tag="IVD66_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAP6146831.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYVLIDEKVKKR"
     gene            3388..3639
                     /locus_tag="IVD66_002665"
     CDS             3388..3639
                     /locus_tag="IVD66_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146832.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            3654..4091
                     /locus_tag="IVD66_002666"
     CDS             3654..4091
                     /locus_tag="IVD66_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146833.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFENIEKNGAFYTIESEEKDNE"
     gene            4084..4791
                     /locus_tag="IVD66_002667"
     CDS             4084..4791
                     /locus_tag="IVD66_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146834.1"
                     /translation="MNKVVYQLTTEDVSQFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNRLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELTVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGQ"
BASE COUNT         1800 a          821 c          985 g         1327 t
ORIGIN      
        1 aagaaccagc agcggattca aaaagaaatc gaattagatc gataaattcc tttcttgtta
       61 atataaaact aacatgttat agttgtgtta gttttatatt aactttaggg gaagagtaat
      121 gaaagacaaa atccaatgta tttttgataa acataatggc aacctatcct tgaaggatgc
      181 tagaagtgaa ggattatcgc ctatgacgtt agatcgatta gccgaaaagg ataaaataga
      241 aaaggtagca ccaggtttct ataccttaaa ggatgcgttc gtggatgaat tgtatctcgc
      301 tcagagtatc tattccagag ggattttttc tcatgagact gcgctcgatc tttttcaagt
      361 aggaacatat atccctaaaa agatcaatat gatgtttcct aaaggataca atgtatcaaa
      421 ggagaaatta gatcagtatg ccattcaacc gcattacact aataaagaaa attttgacct
      481 gggagtcaca gaaacagaaa gcttttacgg caataaaatt ttagtctatg atttagagcg
      541 aacgttatgt gacatgtgga atccaagata caaagcaagc gtagaggtaa aacaagaagc
      601 attaaaagaa tatatgacaa gtaccagtag aaatacaaat aagctaagaa gatacatgga
      661 tattttaaaa tcaccaaaag aaatgacttt gtatatgttg ccactttatt gagaggagta
      721 aagatgaatg acaccgacac aatttaaaga gaaaacaaga aatttcgcag cagagaaaca
      781 tttaaaccca caaattgtcc aaagatatta tatgatggaa aaattattag aatgtattgt
      841 tgaatcgcct tatcatgatg attttgtatt aaaaggggga tttctgattg gatcaaaata
      901 cgggttagaa aaccgttcaa ccgttgatat tgatacgact tatcgaaatt cgaaactaac
      961 aaaagaaaag ttagaaactg ttttttctga attaacagct aatcctacaa aagatggaat
     1021 tcgttttgaa ttaaagggat taacagagac gagggaagcc gattattatc caggttttca
     1081 agcaaagttt attgcttatc ttgaaaatgc acgtgtacct tttaaattag atattacttc
     1141 aggtgattct attattccag cagcattgat gtatgaacac aaattaatgt ttgaagataa
     1201 aacgattcat attccagctt atcctacgga acaaattcta gctgaaaaat tacatgccac
     1261 gtttagtttt ggaaaagata attcgcgcat gaaagatttt tatgacctgt atatgattcc
     1321 gaaattagaa cgtatcgatg agaaaaattt gtataagagt gttcaaggaa cattcaagga
     1381 aagaaataat caatcggtgt ttaagcattt gtatgatcag gaaatgcctc aattggtgaa
     1441 agatgagggc ttgagagaaa agtggaaaag ataccaacaa gaaaactatt ttgccaaaga
     1501 catttctttc gaatctacac taacttccgt tgattccctg atgcaatcaa ttgtagagca
     1561 agagaaggca gaacgaaaac aaaattttaa gagatcacaa caaatgaatc aagaaatgga
     1621 gagataaaga tgatcaataa tgtaacttta gtagggcgat taactaaaga tccagattta
     1681 cgttataccg caagtggcac agcagtggcg actttttccc tagccgttaa tcgtaatttc
     1741 acgaatcaaa acggcaatcg agaagctgat tttatcaatt gcgtgatttg gcgcaaacca
     1801 gcagaaacga tggcgacatt agctaaaaaa ggcagcttga tcggcgttgt cggacgaatt
     1861 caaacacgga cttatgacaa ccagcaagga caacgtgtgt atgtgacaga agttgtggcc
     1921 gataacttcc aactattaga aagtaaagca gcgacagaaa gccgtatgca cgctgatcaa
     1981 tcgtccagca gtccaagccc taccaccttt gaacaacggg atacagcgac gcctaacaac
     2041 aatggattga acgcttcaca gaatccattt ggtggacaat caatcgatat tagcgatgat
     2101 gatctaccgt tctaagtagc attttctatt ggttgcattt gctacggttt atgttataat
     2161 ttagacaaca aaaagaattt tcaatctata accaaaaacc actagctggc gggctagtgg
     2221 ctttctttta cgtttctatt ataagaatta acgggtaggc ttactgtctt tcttggcaaa
     2281 tttacaatca agccatttgc agatatagtg cgcggctact tctgccatga ttgcaaaaac
     2341 aaaatcaaaa agaattttca aacctataac ctcctcccct tgccagatta ggccggggta
     2401 gcagacagca agactattat agcataattg aaatatccaa atgattggat ttttgctata
     2461 attttagcga ggtgattgtg atgaacaaat atgttggttt gcttgataaa atccgagtaa
     2521 taaaaacgca accgttattg gttcgcttta ctttacaaac gattcatgaa tcgattaatt
     2581 gtgtagttgc agatattgaa attatcgata aattgctaat tatggatgat ggaaaataca
     2641 atattgccgt cacaggtcac ttcaataaac gaaatcagct agttattgct agcatgtatg
     2701 ttagaaatcc cgatcatttt acgcgatcga tgggcatata aataaaagaa gagttgtagt
     2761 cctaaatgag gattgcagct ctttttgttt tacatagaaa caggaaaaga cctttttagg
     2821 aagacacaag tgccttctca attgaaaaac ctttctctca ctccaaccgc caccgccgtt
     2881 cgagaagaaa ggaagtgaac gttgcacgtt cactaagata tggtgtcttg caaagcaaga
     2941 caaaatagaa aaaacttcct ctcaccaaaa ggttcgttcc tgttcgctat ctctttattg
     3001 atttgccaga ccggcaacaa gttgcctttt atcaccaaaa agcgacaagg acaagggtaa
     3061 atggcacgct gcgcgccctt gtccttgtcg cttttcgttg attcattctg gccaacaaat
     3121 caataaagaa agaactaacg aaaggaaata aaacctttcc taagaggagg cagaatcaat
     3181 catgcgaaag aaatttgatt attggggtgt tcccttcagc gaattattcc caaactatca
     3241 tgcaccacat actgtcgaat gcgattgtgg agaaagagcg aaatgtatca aaagctatcg
     3301 tttgtatcaa tgtccaacat gcgggaaaaa atataccttg tcttatggcg attatgtttt
     3361 gattgatgag aaagtaaaga aacggtgatg aaaacacaac acaaattatt gactgtaaaa
     3421 gaagtcgttc aaattttggt ggacaaagaa gtcatttctg aaaaagtagc agaagcttta
     3481 cttattccgc ggtactggac gatagaaacc cctttagtag aggatgcacc gactatgcta
     3541 tttgaagacc tagtgaagat tgcaggatat gaactgcatt atcaagaaaa catggaaact
     3601 tatgaaatcg aatattggtt aaccaaatta gagaactaaa aaggagaaaa aatatggctc
     3661 aaaattacta tgacgaattt gtcaaattac ctttggataa aatggcacaa aaaatggagg
     3721 atatgacgtt cctataccat gaaacacgtg tacccaaaaa acattacaag gaaaaattgt
     3781 cagtcgcagt ggaagaaatg attgaatcag gtgtcgaaat gaatctcatt gcgacgtact
     3841 atcgaacact ggaagaactg aaaaaacaaa atggaaaatg gtttttccaa gccttactat
     3901 gcttggaagt aggtgtcaaa ccaagcacta tcaaaccttc cgaatatcaa gccttagaac
     3961 tgacttatgc aaaattcgca cagattaaga aagctaaagc aatggctagc gactggctag
     4021 atacttttga aaatatcgaa aaaaatggtg cattttatac gattgaatcg gaggagaaag
     4081 ataatgaata aggtggttta tcagctaaca acagaagatg tttcgcaatt tttaacaaac
     4141 aaagaacact tgaatgaagt aatcagacgg attcaaaaag actttagttg tatggaagaa
     4201 atgaagtact ttattcaaag agtggaagaa cagttgtata tggaaagtga aacgagtcaa
     4261 acgaaggtta cagtcagcca taatcgttta gacgtgtata aacgtcgtcc tgacacatta
     4321 aaaaaaggag cggagcttct acgactagaa acagaaaaat atatcatgaa tgtttaccta
     4381 gaaaggagtg agctggtcga aaactttgtc agctacacga tttgcaggaa acactattac
     4441 tcagaatcag aatattattc aatttttgag agcatggaat taatggaaga agaaatggaa
     4501 gagctaaaca gcaaagatgc gacggtagac gattattacc ttgtatttac tagatttttg
     4561 acgtgtggga cggaatctat cgtgttaatg ggaatggatt atgaactcac tgtacccgaa
     4621 gcatttttga gggaatatgt agaagaagta gataacccag gcgacgactg gtacacgact
     4681 ttaactgatt ttttagacac ctacacttac gacgatacag aagaaatcca aaatgaactt
     4741 gaccgtaaac gaatgccata tcaacgattt gaaaggaaaa aaggtcaata accatttata
     4801 ccgaaaagtg aggatgtgtg aaataagaac aaaaaacctt gaaattaagg gaatggttct
     4861 tatttcgcac caatcgatcc aaccgccccc gccgcttagg tggtgcgaaa taagcgggca
     4921 aagcccgata acc
//
LOCUS       DACBZK010000125         4893 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.131, whole genome shotgun sequence.
ACCESSION   DACBZK010000125 DACBZK010000000
VERSION     DACBZK010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4893
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.131"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..563)
                     /locus_tag="IVD66_002668"
     CDS             complement(<1..563)
                     /locus_tag="IVD66_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HAP6146835.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
     gene            complement(750..1400)
                     /locus_tag="IVD66_002669"
     CDS             complement(750..1400)
                     /locus_tag="IVD66_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146836.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            complement(1943..2878)
                     /gene="whiA"
                     /locus_tag="IVD66_002670"
     CDS             complement(1943..2878)
                     /gene="whiA"
                     /locus_tag="IVD66_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HAP6146837.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(2912..3910)
                     /locus_tag="IVD66_002671"
     CDS             complement(2912..3910)
                     /locus_tag="IVD66_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HAP6146838.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(3907..4791)
                     /gene="rapZ"
                     /locus_tag="IVD66_002672"
     CDS             complement(3907..4791)
                     /gene="rapZ"
                     /locus_tag="IVD66_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HAP6146839.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
BASE COUNT         1486 a         1051 c          757 g         1599 t
ORIGIN      
        1 tctataaaca tcaccccaaa taaaacagaa aacagtataa gcattataaa aattatcaac
       61 aaccttgatc cttcttttat agattcagga aacagtataa ttttagtact agataaattg
      121 tttacaccga ttagtgttaa aatatcttta ttcttcttgc taacataacc ctttatgcac
      181 aaaagaacag ctatacttaa agtaacaaat aaataacgta ttccaataga aaaatcacta
      241 taaatactct ctagcatagg accgacaatt gaagaagtca ctactgcaaa tgctggacct
      301 atccaagcaa cattagaatg ttctttctct cttttccttt gtaaatcttt gttgagtatt
      361 aatctattta tttcttctgc aggcaagtta attttcataa ccttatgggg gattatccaa
      421 ttaaaaatcg gaaaaaggta gcctccccaa aaagtatagt gatctgtgtc aatcagataa
      481 taacctgatt ttgattccag aataacatat ctcaaagccg aacgaaaatt tttcatgaat
      541 atccataatc tcactgtttc cacacctaat tcctccaatt ccaattaaat ggatttatag
      601 catcaccaat tatgttaact gcctgaccaa cctcattgat aaaattggca ccactatccc
      661 atgcttcaac aatgctatat atctatcaaa caaaaaatgg aaaactaaat actcgcgcac
      721 ataaatttta cattctgttt tttataagac taataataat cattgaaaaa atttcttatc
      781 ggtggcgcat attcccaatt gattaatgtg atcccatatt ctgcaagtat tttacgagct
      841 tcttctaagt catagtgaga aaaatgcata aaacctgcaa tacgatcacg gactgtgagc
      901 tgtggcttgc ttccaccatc attcataaaa tatccagcag agccactact taaagtgatt
      961 gttacatctt cactttctat tattaagaat tcataatgaa atgctttcaa ctctccacta
     1021 ttatttaaaa gttttatact ccaacttcgt ctaggttgag ttgtcacatt ccctctaaaa
     1081 cttcctataa attctgcaat caccgtatct tcaatcaaaa ttctttcctc atctatttca
     1141 tattcaagac taaacggaaa ttctccatat gtaatctctg gcaatggtgg tgctgtagtt
     1201 ctccaaataa atacaataac tgtgaataga aaaaatccaa cgatcgatat aaatgttatg
     1261 agacctgctc gaagtaaaac ccgatataat aaaaatgctg tatttcgctt tgctatatct
     1321 agaaaaataa aaagtactgc aatcataatg atagtaaaag ttgtaaaaaa gcacattttt
     1381 tgccctccct ttataaacat cgattctcaa attctaaacc aaatcttgat agttcaagtt
     1441 caggtataac gtataccaac catacatccc aattactatt tatgaactta tgattatcac
     1501 tgaataaatc actccatccc cttgttaaaa cttctacatt aattacacct ggttgttttc
     1561 gactagctaa tccaatgaac ttatcaacca tccttatcca ccaaccacga gaatcttgac
     1621 cagaagtaag aaaaacagtt ctcaaggttg atcgagcagt tccttccagt ttttaattaa
     1681 tctccagtta tagataaata cttgatccta tctatatcag gacttctata ttaagcaaaa
     1741 gtttatgtat aaaactaaaa tcttcattca gttgtctccc cgctttttat acgattgtat
     1801 taaaaaacaa tagaagcctt tcaacattat gttactccag taaagttgga attatagttt
     1861 gacggaagaa aagcaagtat agcttttaaa aaaaactgat acattcgcat ctcctgcttc
     1921 atgtatcagt tttttctttg gattaaactg cttcttcacg cagtttttcc gcaaattcat
     1981 ttattttgcg aattcggtga ttaattcccg attttgatat tgcacctgag ggaatcattt
     2041 cccctaattc tttcaagctg acctctggat gttgaagccg aagttctgcg atttcctgaa
     2101 gtttttcagg aagggcatgt agaccgacct ttgcttcgat caattcgatg ttttcgattt
     2161 gtttagaagc cgcatcaatc gtcttgttca gatttgctgt ctcacaattg actagacgat
     2221 tgaccgaatt tctcatatcc cgtacgattc gaacatcttc aaatcggagc attgagttgg
     2281 ttgcaccaat caatgttaag aaatcagcaa ttttttctgc tccttttaaa tacgaaatat
     2341 agccattgcg ccgttcaagc gttcgagcat gtagaccgta ataatttaac atatcgcaaa
     2401 tgtcttggtt atgctgttca taaatagaaa atatttccaa atgataacga ctcgtttccg
     2461 gattattgac tgaacctgag gccataaaag caccacgtaa gtaagaacgc attttttgcg
     2521 aatttcccat aatctcgtcc gaaacgtgtc cattgaacat cataccatcc atgatatcaa
     2581 gatccatcaa cacatctttt gtgccttgct tcaaccggac gatatagaca ttgttctttt
     2641 ttaatttcat ttttttacga acgagtagct cacttcgtac ctgataatga tctttcaaaa
     2701 gagaatagat acgtctggca attgcagcat tttctgtttg gacgttcaaa ataaactgct
     2761 ggttcacaat acctaaagag ccgttcattc gcagcaaagc agctaattcc gctttcgcat
     2821 gttctcgatg aacttccaaa ccagttagtt ctttcttcac atctgcagca aatgacatcc
     2881 tattctcctc ctttctccaa caataaattg cttaatattt tgaaccgaaa actaaacgga
     2941 acaattcttc tactactttg tctccatcgt ggaagacacc accatctttc aattctaaaa
     3001 agtcggtgga aatcactcga catccttcat ttctcaatcc gttgaagtcg tgtgcgactt
     3061 gtactagata ctcatcatag atctctgggt ccatataatc ttcaggcact ttttccgtat
     3121 tgaccaatac tgtatcgata aaaggctgat tcaaatgctt gtgtaaaaca cgtatatgat
     3181 cggcatctgt gaaatgttcc gtttcccctt tttgggtcat gatattacag atatagacgg
     3241 tttcagcagt tgtcttgagc attgcttcgc cgatttctgg tatcactaaa tttggaagga
     3301 tactggtgaa taaacttccg ggtcccaaaa cgaccatgtc ggcgtccata attgctgaaa
     3361 cgacttttcg agccgctttg gcttcacttt tatcatttgt gttgcagaca tacacacggt
     3421 caatggtttt acggttgatc gcgattttag attctcctac tgcagtcgtt ccgtctttaa
     3481 aaacagcatg caaggtcaaa ggagtttctg aagaaggata aacatgtcca tctacatgca
     3541 tcatttttgc taataattga atcgcctcat aagtgcttcc ccgcatctcg gaaactgcgg
     3601 caatgatcag attaccgatc gtatgattgg ctaaaaactg atcttccttt ttgaaacggt
     3661 attggaaaat atcttcatag aattgtggca tatccgataa cgccactaag acatttctca
     3721 agtcaccagg aggagccata gcgatcgatt ctctgattgc accgctgctt ccaccatcat
     3781 ctgcaacagt cactactgct gtgatatctg ctccttgatt tcgtaaactt ttcaggataa
     3841 ctggcagacc agtgccaccg ccgaccacta cgatctttgg ttttcttatc cggtaggttt
     3901 tcattttcac gaccggttca ccgtctcttt ccttttatcc ttgtcccgat gtgtcacatt
     3961 gactttatag tttttcccta aagcatttgc caaacgttca gtcaatgcca cagaacggtg
     4021 ttgaccgcct gtacagccga ttgcaactgt caagctgctt tttccttctt taatgtatcc
     4081 aggcaataca gtttccagaa gatccaaaaa tttatggtag aatgattgcg tttcatcaaa
     4141 ggacatcaca taatcataga ctggctgatc ttttccggtc aatggtctta gttccgggat
     4201 ataatgaggg ttgggcaaaa aacgcacatc catcacaata tccgaatcga tcggcaaccc
     4261 gtatttaaaa ccaaatgata caaattcgat ccgaaatcct tggtctccct ttgatttgaa
     4321 tgactcattg attttttcac gtaattgtcg tggtgtcaat gttgtcgtat caatgatcac
     4381 ggaagcttgg gctttcaagt cgtctagtat cgcccgttct ttacgtatcc cttcagtgat
     4441 caaaccgtcc atcgccattg gatgtgctcg tcttgtttct ttgtagcgag ccactagttc
     4501 ttcgtctgaa gcatctaaaa ataagataga agtgtcgatg aagttcgtat tttcgatttc
     4561 gatcagcatg ttttggattt cttcaaagaa ggaacgagaa cgcaaatcca ctcctaaagc
     4621 catttttgtg actttacctg attctttgat caattcccag aattttggaa tcaatcgagg
     4681 cggcatatta tcgatacaaa aatagcccat atcttcaaaa ctttggatag ctactgtttt
     4741 ccctgcacca ctcatacctg ttatgatgac taattgcaaa ttatctgtca tatttacgaa
     4801 cccctctcac attgtgcata ataaaattat atcatcccgg gcgtatcatt accagttttc
     4861 tttttctttt acaaaaagat ttggaccaaa tat
//
LOCUS       DACBZK010000126         4791 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.132, whole genome shotgun sequence.
ACCESSION   DACBZK010000126 DACBZK010000000
VERSION     DACBZK010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.132"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(75..1073)
                     /locus_tag="IVD66_002673"
     CDS             complement(75..1073)
                     /locus_tag="IVD66_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAP6146840.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1148..1444)
                     /locus_tag="IVD66_002674"
     CDS             complement(1148..1444)
                     /locus_tag="IVD66_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP6146841.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1437..1730)
                     /locus_tag="IVD66_002675"
     CDS             complement(1437..1730)
                     /locus_tag="IVD66_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146842.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1876..2427)
                     /locus_tag="IVD66_002676"
     CDS             complement(1876..2427)
                     /locus_tag="IVD66_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HAP6146843.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2601..2900)
                     /locus_tag="IVD66_002677"
     CDS             complement(2601..2900)
                     /locus_tag="IVD66_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HAP6146844.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEIGTLPKDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            complement(2927..3235)
                     /locus_tag="IVD66_002678"
     CDS             complement(2927..3235)
                     /locus_tag="IVD66_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAP6146845.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQLPLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEERKEYLISPKLRLKSVSQKIWAIDSGEYQTMLLPEEY
                     "
     gene            3480..4223
                     /locus_tag="IVD66_002679"
     CDS             3480..4223
                     /locus_tag="IVD66_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146846.1"
                     /translation="MVVSKLPRNEDYLTNYDGYVVTTEHFDLANPVTKVDDIPDYEMY
                     SQTIDSLNKRFGNRVLKGIEIGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDD
                     EVKDMDPAIVIPQYFAQLSEALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPIL
                     DQVIKNKLAFELNAKSAYLYDNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFD
                     DLFALLKANGVTELAIYQKGKRIMVPLPV"
     gene            complement(4260..4757)
                     /locus_tag="IVD66_002680"
     CDS             complement(4260..4757)
                     /locus_tag="IVD66_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6146847.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT         1424 a          908 c          700 g         1759 t
ORIGIN      
        1 taaaaaaact gattctaaga aaattaaata atttttctca aaatcagttt ttctttgata
       61 aataatattt tcaattattt aatcatttga aaattgttag tcattccaat acgttgagaa
      121 attcttccat ctgtataaac acgaaattgt tttccaccag ccatggtcgt gtttccatca
      181 tcatccgtta caatattaat tgaatagtag cttccatttt catcttgcat tagatctttc
      241 atatattcat ttgtgctaat taaattagta tttgatacat ttttatcagg agaatcatac
      301 aaccataaag ctttattatt tagcacagat tctttagcag cttcccaact tgaaattcct
      361 gaactacttg tagattgtgt cgttgtagtt gttgcttgtt gagtagattc ttctactact
      421 ggtgtttgag gagtttgtcc attcacaata tcactgaaac cttgttttaa ctgttgattt
      481 tgagtttcgt taaagtacag ataattattt tcattacctt gattttgttg cgttaaataa
      541 actttaggtt gtccattttg aaaaccgaaa aagtaaacat gctgccctaa atattctcca
      601 gtttctacat cagaataaac tgctactaaa ttgaaatctg catgaccagt tccatcttct
      661 gaccattgta cggtaactgg tgcttcattg attgccattt tccaatcgcc attaatcacg
      721 gcttgtggta aaggagtgcc atacagactt acattattct gaagattgta gcttttatat
      781 tcttgaccta atgtctttcc ccattgtgtg acaaaagttt ctaatttgga agctttattc
      841 gtatcccaca aagtattctt aacctcttca gaagaagatt cagtgattga acttgcactt
      901 gtttccacag attgcttcat ttctgttgta gtttgttcag ttgattgcgt tttacttttt
      961 ttagtctcaa ttgttgtatc agtttctata gtcgctttag tcctcgtatt ctcagatgta
     1021 caaccagtga ataaaattcc cattcctatt agtaataaca gccatttttt cattatattt
     1081 ccccctttca atttctccct cacgtactta ttctatcaga caattaattg atctaaatgg
     1141 taatctttta atcgattctt tcccaataat gtcgatagcc cgtatggcag cggtctcttc
     1201 cttgaggact ctcagatgga ttaaaactag tagaaatttc ccttccacat cctctacagc
     1261 gataagttct cattattttt gggctattag tattattttt cttagttaga gctatgagtc
     1321 caactatgat taccccaact gtcttaatta cttttccttt atctatattc ggatgcgcaa
     1381 gcatatattt atataaccaa tatccaccgt aaattaaacc acctaataca atcagcttag
     1441 ccatgtactc gtctcctttc tttttgttta attacttttt gaatccatct tgcagagaaa
     1501 ccataaactt ctgtcaattg acggatatct acagtttttt cctgttctat catgttttcg
     1561 attctttttc taactaactc acgatcgtac attttcattg gaaaagaaat ctgttgccct
     1621 cgaaaagcaa gataaaattg atagagcaat tctgaatcca gttccatttc ctcaaaaaag
     1681 tcattcatac ttttataaga gttactcaaa caagtttcat caatctccat ctacacaccc
     1741 cctgttattt tttacataat gaaaatagca tattactggg tacattgata attcatataa
     1801 catgtatcat cacatgtatt tttaaagtca aaaagcatgt aaaactactt ataagtaaca
     1861 tgagaaaata aaatgttatt tttcttgaaa taataattga ctatctgcca attgccattc
     1921 attacgaaca tgaatactta gtgggtggga taacttacct tctgcattta tcaatacttt
     1981 ggtcatcttc ttttgtttcg cactcaattg atcgtaaata gtctttgctt gttcataagc
     2041 cacttgactc gtcgctgtaa tcgaaccaca agcaaaaata atggtattga ttttcttttc
     2101 tgtaaaaaca gtcgttaata tttccaaaga ttgttcatca tttcctcgaa gaaatacccg
     2161 aggacttttc gcttttgtgt acgaaaaaag attcacagca ataaaaccag taaatcctaa
     2221 ttgtcggata ttcttttcga ttaataacat actcaaatca ttcgtaaatg gttctgtatc
     2281 tgttggacga atagtaatga ctactgctaa tttatcttcc gcttcttttc ctttgatcgc
     2341 ccattgtcgt ttgaaaacat agcgatgggt atgatgagga tctcgccaaa cttctgtttg
     2401 tgtggtcact aattcttttt caatcatctc tttttctcct atgctatttt ttgttcaagc
     2461 acttcaatta ccattgccgt tataagtgtc aatactagtt gaaaatattt catattcttt
     2521 ctcctttttt cttcagaatt tgatgaatcg cggtaaggat atcttctaaa catttcgcaa
     2581 tcattctcaa ataatcgatc ttattcatcc gttcctccaa tctgactcca aaccaatcgt
     2641 ccttctacca gtaacccacg aacaaattct cgctggctgg taatatctgt aatgaaataa
     2701 actacatagt cttttccatc ttctggtgcg caataaatat aaagatgtgt catcactaaa
     2761 cgtggtagat gaacatcttt aggaagtgta cctatttcaa tttcctcttt ttccatcgta
     2821 acggattcat agccccactc ttcagaagca gtgaccagct gtgcacactt ttccagtact
     2881 tcgatagccg tttctaacaa gtcctttcgt tcctttcttt tagatactag tattcttctg
     2941 gtaataacat cgtttgatac tcacccgaat caatggccca tattttttga gacactgatt
     3001 tcaaacgaag cttaggtgaa atcagatact cttttctttc ttccggttct tcttgacgat
     3061 gaaccaactt ttgatttcct ttttccgtag aaaattcaaa aatttgaaga tagtctaaag
     3121 gaagttgctt ttgaacgttt tgatcgatta gattccaaca taaagcttgt aattccaccg
     3181 gcaaactgtc cattactccc tttgtgacat aacgttgtcc tttattttga aacatttctt
     3241 ttccctcctt tgctataaaa atagcccaat cttctattaa agaagattgg gcttcatgga
     3301 tataatatat atttgtaaat aaagttaatt cagttataat tatcaaaact acacaattat
     3361 taaagttttt catatctctt tgtttagtaa gtttttctaa atcttaaccc gtggtgctag
     3421 ttaatttttt cctagaggaa aatgtctaaa catgttggta aatcaacaaa aaaacgcata
     3481 tagtagtctc aaaactccca agaaatgagg actatttaac aaactacgat ggttacgtcg
     3541 tgacaactga acattttgac ttagccaatc ctgttactaa agtcgatgat atccccgatt
     3601 atgaaatgta cagtcaaaca atcgatagct taaataagcg ttttggcaat cgtgttttaa
     3661 aaggcatcga aatcggttac atcgcttctg aaaaggatcg gatcatcgac tatttagccg
     3721 ataaagatta cgatttaaaa ttactcagtg tgcatcataa tgggcaattt gattatttag
     3781 atgacgaagt caaagatatg gatcctgcta ttgtgattcc tcagtatttt gcacaacttt
     3841 cagaagcact agttgttata gaagcagatg tctttgctca ttttgactat ggttttcggg
     3901 tatttggtct atccgttgct gaatttaaac aatatgaagc gcagttttta ccgattctag
     3961 atcaagtaat caaaaataaa ttggcattcg aattaaatgc taagagcgct tacttgtatg
     4021 acaatttagc gttatatgaa tatgtcatcg atttatatct ttcacgtggt ggtaccttgt
     4081 ttagtgttgg atcagatggg cattaccttg aacatttccg tttccatttc gatgatcttt
     4141 ttgctctgtt aaaagcaaat ggtgtgacgg aattagcgat ttatcaaaaa ggaaagcgaa
     4201 ttatggttcc attaccagtc taaaaaaacg tcctcagcat caaaagtgag gacgtttttt
     4261 tagatttctt tttctaaaat cggacaaata cgatcttgtt ttcctaaagg aaaatgtttg
     4321 atcccgattt ttttaaatcc atgacgttca taaaaacgaa tacctgcatg atttttttca
     4381 taaacagtca aacgtaaata acgtttttgt ttcgttttag cataacgatt cgcttcatcg
     4441 agtaaccgtt gccctaaccc tttgttttga taatctttga gcagatagag ccgttgaatc
     4501 tctatagcat ctttttcatc attgactttc atataaccaa tgagtatttg atgatcctta
     4561 ataccaataa atttactggt tgactgtgcc aattctactg ccaatatttc agttgtcaat
     4621 tgtgtctgta aatatccttg catatcaagt ggatctgcgc catcgataaa cgattcataa
     4681 aaactgacaa cacttacaac ttgtaaagca tctagatcat cataatctaa atacgctagt
     4741 gtgatttgat tgttcatcta actcctcctt ttgacatagt atactataaa t
//
LOCUS       DACBZK010000127         4680 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.133, whole genome shotgun sequence.
ACCESSION   DACBZK010000127 DACBZK010000000
VERSION     DACBZK010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.133"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(92..943)
                     /locus_tag="IVD66_002681"
     CDS             complement(92..943)
                     /locus_tag="IVD66_002681"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HAP6146848.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(1097..3670)
                     /gene="mprF"
                     /locus_tag="IVD66_002682"
     CDS             complement(1097..3670)
                     /gene="mprF"
                     /locus_tag="IVD66_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAP6146849.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            3811..4617
                     /gene="proC"
                     /locus_tag="IVD66_002683"
     CDS             3811..4617
                     /gene="proC"
                     /locus_tag="IVD66_002683"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HAP6146850.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
BASE COUNT         1462 a         1026 c          809 g         1383 t
ORIGIN      
        1 ctcatatcta gccatttcac tacaataaaa aactgaagaa taccatttta ggattcctca
       61 gtttttcatc acctatttta cttcttatat tttattgcag ggttcgtact aaataaactt
      121 cctcacaaaa accttttaac ccattatata ctctctgcgc tcttgaataa tgttgacaca
      181 aggcaaaaac ggttggtccg cttccactca tcaatgcagc atctgctccg tacttgatca
      241 tacgctcttt gatttgatgg atgactggat gccgctttcc cgttatatct tctaaactgt
      301 ttcccatttt tttgatcatc tgctgataat cttgctctcg gatggcttca gcaagtccgt
      361 ggatgtcttg atgttggatg gcttgcgtat ctacttctct aaacactgta cgtgtagaga
      421 cactcattct tggtttgacc aacacaaccc agcactgtgg catagaaggt aatacttgga
      481 tttcttcccc tttgccaccg acaaatgccg tacttccgta gacacagtaa ggaacatctg
      541 taccgacttc caaaccgatt tctgccagtt cttctaacga acagcccaga ttccataatt
      601 ggttgatccc tcttagagca gctgcacagt ctgtacttcc tccgcctaat ccagctgcta
      661 ctggaatatt cttcttaaca aagatcttga caccggtttt gatattgtat ttatttttta
      721 gcaataaagc agcttgataa acattgttcc gttcatctac cggtaaaaat gctttatttg
      781 tttctacaat gattttgtct tctgttattt cttcaaaaaa tagatgatct gccaagtcta
      841 cgctcgacat caccatttcc aactcatgat acccatcttg ccgtctatat aatacatcca
      901 gtcctaaatt tatcttggct ggcgcttttt caatcaattc catcctctca cccattcgaa
      961 aagtctaagt cgcaagtatt ctatcatagg gaaaaataaa agtatagctt atgtctgcct
     1021 agtggttgat tttgtcatcg tttcaacagc tttcacagaa ttttctcttc ataatccaaa
     1081 caagttctag tgattcttat aattctgtga gcacttcttc tgccaaactc ggaacatttc
     1141 ctttttcttt tcctatcaga ctgagtagct gcatggtagc aaatccgaaa ttacttcctt
     1201 tcctataagc aaaataacgt ccttcccaat gatcgacata ttttaatttc ttttcataag
     1261 cagactggaa ggaatagaaa aaattaccat aattatatac gatatgcatg actttttctt
     1321 gaaagaaaga aaaatctgtt tctccaacat tagctaatgg agctaagcct agattggctt
     1381 ccgagtagcc cattttctcg tatacaataa acagattggc taacagatag tcagctaatt
     1441 cctcagattc tttaggtaag acccgcaaca aatcatatcc cgcctgcttc ttcgtcatcg
     1501 gctgagcggt gatgaagcca acgacttttt gatctttacg gacaataccg acaccgctag
     1561 ataatacata tgatttatca aatcgtccca cagagaagta tttttctcgt gcaccttgaa
     1621 gccatttttg tgaaacttca tttacagctt gatgtaattc ttccggcagt tgatcgtacc
     1681 aagtaaaatg gtatccttct ttcatcaaac gttgatattc aagttgctga ctcagccgag
     1741 acaagtcttc tgttgctaga tcaacaatcc ctgcttcacc tactttcgtg aagtgaaaac
     1801 ccaattcatg aagcatcact acgtagcttt ctgatatctt ataaaacgca agctgatagc
     1861 ctaaacaatc tgcttgtttc ataaactgat tcgttgctgc ccgcatcatt ttaggattgc
     1921 caactggatc tcctaaaaca aagcatttgt ttcctttgat ctgataacca aaaacgactt
     1981 gatcttggtc gtcttcttgg taataaaaat aactgtaacc tgacaagcga agctgatggc
     2041 ttgtagctgt gcctccgtat gtttccaata aacggtcaaa acggtctttt tcgtactcac
     2101 tgccaagctt cgtagtatct tcagctaaat attgataaag cgccactaaa gctagcaatg
     2161 agatgcccaa accaataagc cctgagaacc acacatcatc tgaaggaaac aaaataaaat
     2221 gatttcctgt tattcgaccg actaaaaagc gtccgctgtg atagcctgca attgcgtaaa
     2281 cgataaacaa aaagccgaac aagctagcat caaagattat agctccccaa gaataaacga
     2341 attttgttcg ataaaattct tttctggata accacacagc taacagaatc aagacatata
     2401 ccaatatcaa ctgccaagat aacgtacgtg tgattgtatt taaaatacca aaagatagta
     2461 aagcaatcgt aggcagaaat gcctttttga cttttactga aagtgctcta gcaaggccga
     2521 gtaataaaaa gccaaccaat agattcactg tctgatctaa aaaattgaat gagaacggca
     2581 ataatacttg aaatagccga ctgattgcag acagattagt gattgttgat agaagtacca
     2641 tcatgatccc cgcaaaatag acagcactta cgagcacgat atgcgcaacc ttttggaaaa
     2701 acagtcgcgg aatgttatct aaaaatcgat tgattttgac tcctgtatgt gtgatgaaca
     2761 atagaagtcc cgtcataaaa ggtagaacat aataaaacaa ccgataatat aatagccaaa
     2821 ctactgctac atcttgccga acagacaatt gactcattcc taagatcatc aaaacgtcaa
     2881 aagtccccat tccacctggg accatcgtca gcattcctat caatgtagca atcatgaaca
     2941 taggatagat cgaaagcatc gaaatatcta ttctcatcaa cttgccgatg atcaaaaata
     3001 ccgcaagggc tcccgtccat tgtccaaagg atgccagtag cagaccaagc aagccttttg
     3061 gataaaactc gaagaacaat gtctttctct ttagataagc aaaaaagaaa atgactggtg
     3121 ctaaaaaact accgccgaaa agccagatcc aatagcttcg aaaaatactt tctgactgaa
     3181 taaaaaagac atcaataaat gtaagaaacg accatacaga caaaccagtc agcataaata
     3241 gtgcgacttt tgatacagtg gctaaaacca tttttctatt tgtctgcttt ccataaaaac
     3301 tagcccgcag acttgctcct accacaccac caaaaccggc gagattgttg atcgtgtttg
     3361 ttacccacgc agcaagaaga aactcttttc tttccatttt tggttttcct tgtttttcta
     3421 agactctgat cgtcacccaa tcatacaaca acatcggagt gacacccagc agtccagcca
     3481 gaatcatgag caggatcgtc atgcggcttt gttgtcccat cctttgccaa atatcttgcc
     3541 aactcatgcc attagcaata tttgcgactt gatttgccac aaagactaac acggagccga
     3601 aaaaaatcag ttttaaaatc agactatgtt cctttatcca ttgcagcatc aagtatcgtt
     3661 tatttttcac attttcccat tcctaacttg tatacttttg tgtcataccc caatgttatc
     3721 ttatttattt taatttttcc actttagacc tgttctttgc ttgcgatgat agaaaaagaa
     3781 agatatccta atgctaaagg agaggataac atgaaagtag gatttatcgg cacagggaat
     3841 atggcacaag ctattattga tggtttatta aaaaaaggaa cagtctcgaa agaagaggtg
     3901 ttcgtttcca gtggacattt tgaaaatgca caaaaatttg ctgctgaaac tggcgtccat
     3961 gcatgcaaaa gtaatcagga agttgcatca caatcagata tcgttctttt agccgtgaaa
     4021 ccaaaaatca ttgaaaaagt attggaagaa ctaagagaat atagccagaa agtcttattc
     4081 atttctattg cttcaggaaa atcattaaca gatttagaaa cagcgcttga agatcctcag
     4141 gcctccatcg tacgtgtgat gccgaatgtc aatgtcagcg taggagcagg cgtttctgcg
     4201 atttgcaaaa atgaagctgc cacggaggaa cagcttcagc aagctacgat gatttttgaa
     4261 gcaatcggca gcgtctatcc tttagcagaa tcagatttca gtacattcat tggccttgct
     4321 ggcagctcac ccgcattcgt ttacatgctg atcgatgcga tgggacggac tggtgtactg
     4381 aatggtttgt ccaaacagac agccactgag attgctgcaa aagcaattat gggttcttgt
     4441 caaaaattcc tttcaagtga taaaaatcca tgggaacttg tagaccaagt ttcttctcct
     4501 ggcggtacaa ctgttgcagg tgtagttgcc ttagaagaag caggattcat cccagcaatc
     4561 atcaaaggaa tcaatacgac gatcgagaaa gatcttgaga tgttgaataa aaaataatga
     4621 tagcaatgtt ttttcgtacc ttacaaaaaa agaagagctg tggcttttgc cgcggctctt
//
LOCUS       DACBZK010000128         4662 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.134, whole genome shotgun sequence.
ACCESSION   DACBZK010000128 DACBZK010000000
VERSION     DACBZK010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.134"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(172..474)
                     /locus_tag="IVD66_002684"
     CDS             complement(172..474)
                     /locus_tag="IVD66_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146851.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(694..1060)
                     /gene="ssrA"
                     /locus_tag="IVD66_002685"
     tmRNA           complement(694..1060)
                     /gene="ssrA"
                     /locus_tag="IVD66_002685"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1231..2004)
                     /locus_tag="IVD66_002686"
     CDS             complement(1231..2004)
                     /locus_tag="IVD66_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP6146852.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2148..2498
                     /locus_tag="IVD66_002687"
     CDS             2148..2498
                     /locus_tag="IVD66_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAP6146853.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2479..3195
                     /locus_tag="IVD66_002688"
     CDS             2479..3195
                     /locus_tag="IVD66_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6146854.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3195..4643
                     /locus_tag="IVD66_002689"
     CDS             3195..4643
                     /locus_tag="IVD66_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP6146855.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
BASE COUNT         1550 a          822 c          900 g         1390 t
ORIGIN      
        1 ttataattgg agtggtagtt aattagtgac ttatttttga ttttatagca ctgatactat
       61 aaaatataga tatcatcata ttacacaatc ttaatactaa cttaaaaaat atccctttta
      121 taagtatggt gataaaatcc gttccgggct acctttttta ggtagcctac tttaatcttt
      181 atacctttct ggatcaacga aagtatactt caaatagtca taacgccgat gatcgctccg
      241 tgcgtctggc acatcagtca cgatatcaaa caaaaaatac acatctttct tcattctggt
      301 ttttgttgcc ggaattttaa agtagttctt attagagtaa tagagattga ttaataagct
      361 atcttcgatt gctaaaaaga aaacttctga atcccacacc ttataaaaat ctttgacaaa
      421 tctattcgaa ggatcaaatt taaaccataa ttgtgttttt ccttccatca acataatgtt
      481 cacctcaaaa agagtatacg aactaatgtt ctttttgtaa agtaggaata tcattgataa
      541 tatggatgga acatatatat taaaaagtgt tctttttgaa tgctattttg aatgccattt
      601 tcattcattt aacgaaaatc tgcgaaaata aaaaatgctc aaacccttat aaaataagga
      661 tttaagcatc tagcgaaatc tgctgaaatc tcacaatgga gacggcggga gtcgaacccg
      721 cgtccaaaca catcgccact taaaaatcta cgttcatagt caactcattt aaggattcac
      781 tttacagctt gccgagtgac aggcattctg tatcgctagt ctgatgttct ctttttcaac
      841 ttacagacgg aaagttgaaa cgtatcccac taaagttagg acccttactc gagcacatgg
      901 gcgatgccga gaggatctac gctaactgtt tttaggcagc taaagcgtaa gagttgtttt
      961 cgtttttagc agttatattt aactgtaacg tttttacgta gacgtaacct acgaaacgca
     1021 attcaagctc gactgtgcct gtcgaatccg taacgtcccc gttagctaac aagggttacg
     1081 tgtatttttc atacaaaatt agtatagcat atattgggat aaattcaata aaaaagcgaa
     1141 tcatatccca ttatttatat aataactgcc cctttcttaa gaaaaaataa gcgattttct
     1201 taagaaaaga ggtagcttca aaaaaagatc ttaaatcaga tcaaaatact tcaatgcgtg
     1261 gacaattccg ccttctgtat ttttctttgt gataaaggta gaaagttctt ttaatccgtc
     1321 ataggcgttg cccatagcga ttttgttgtc gcaagcttcc aacaaggcaa aatcattcgg
     1381 accatcgcca aatccaaaag taggaacttt ttccagctga agttcttttt gcagacgttt
     1441 gacacctgcc ccttttgaga ttcctttctt cactgtatcg atcgagtaag gaccattccg
     1501 ataaaaagtt agctcaggaa aatgttcgtg atagtattcg tcacctgatt gagataagat
     1561 cagcaacata tttactgtgt tttctttaaa gcctaaagga tcaatttccg gaacatctga
     1621 atgaatgaag tcgtaagcat tgatcattgt ttggctatga ccggtacacc agattttctg
     1681 atcgttatag taagaaagtt catgaccgtt caactgtaca tgatcataca ttttttgaca
     1741 ttcttctgaa gaaaatgttt gagaatagat ttcttcgccg tctactcgaa tgaaagaacc
     1801 attcatggtg accgcagaag taatgcccgc atcttccatg atagagtgga tttctgcttc
     1861 tgtacgtcct gtagcgatga cggggagaac attgttttct tttaatgcgt tcatagcttt
     1921 tgccacttcg ggtgtgattt ttgatttcgc atctagtaat gttccatcaa gatcaaagaa
     1981 agtgattgca cgataatttg acacaaataa aactcctttt ttattggaat aagtttatct
     2041 taacaaagaa tgaacaaaag acaaaccttt cgtgaagaat tcctgaacat attggttcag
     2101 tcaacaattt agagtatact ataagaagag aatttaggag ggaaagaatg atttttttca
     2161 gtattggtat cttattctta ataattggca gtctttttcg gattctgccc tcaaaaggaa
     2221 atctgccttt ttatgggtat cattcgcctc ttgccgcaaa aacagacgct cattggcggc
     2281 tggctcaaaa gacaagcgga aactggtttt ttcttatggg cttactgatg gcattgatcg
     2341 gctattattt aaagacatct gggcatacga attattttct gattgaaatg cttctgctag
     2401 tatttccaat tatgcctatt tttattatga cagaaaagaa attacagaaa tatgacctgg
     2461 aaactggagg gaacgataat gaatatttta atgattgaag ataatcaatc tgtttctgaa
     2521 atgatgcaga tgtttttctt aaatgaaggt tgggaagcaa ctttcaagta tgatggaaaa
     2581 gaagggctcg atgccttttt agaaaaccca caacattggg atatgattac actagacctg
     2641 aatttgccca cactggacgg tatgctagta ggaagagaga tccgcaaagt ttcaagtact
     2701 gtgccgatta tcatgctgac agctagagat tctgaaagcg atcaggtgat cggcttagag
     2761 atgggggcag atgattatgt cacaaaacct ttcagtcctc tgacgcttat tgctcgaatg
     2821 aaagctttgc atcgccgtag tgagttggca gaagcaagag aagaagcagt agtttcagat
     2881 gatcattttg atatcgagac tagtcatttc aagatgaata cgaaaacacg agaagcgtat
     2941 ctggacaacc ggccaattga aggactgacg cctaaagagt tcgatctatt gtttacttta
     3001 gcaaaaaaac cacgtcaagt attctctcgg gagcagttgc ttgaattagt ctgggattat
     3061 cagtactttg gtgatgaacg gacagtggac gcccatatca agaaattacg acaaaaaatc
     3121 gaaaaggtcg gaccacaagt catccaaact gtttggggag tcggctacaa attcgatgat
     3181 tctggtgttg cctaatgcgt tatttgtatc agcaactctt agctttctgc ggaatggtcg
     3241 cgttgatctt attgatcgtt ggagtttctt ttacacaact gacaaaacaa acgattgaag
     3301 aaaacaatta ccagcaactg tttggatatg ctgaatcagt tgaaaagaca acgcaaacct
     3361 atgccgatac gctcccgcag tttagtcaag atcaggcgtt tcaaaatgca ttgctgctga
     3421 cagagcaagt actgacagaa caaaatgtga actttatatt tatcgataaa aacgaacgtg
     3481 tcatttatcc gactaataca gctttactga attttacctt aacagctgat caatggaaaa
     3541 atctgaggaa tggacgtcaa gaaaaattca catcgaataa aaatatttta ggacaagcac
     3601 aggcgacctc ttacgcactt gtgccattta atttgaatca tgaattctat ggagcacttg
     3661 tagttagtca acctgcgcga aatatcgata acagcgttcg tccaattaca ctgaacctgt
     3721 tcaaaggatt tattttttcc agtatcgttg cagttattgc cagctatgct tttgcagcat
     3781 tccaagttaa gcgtatcaat cggttaagga atgcgacgaa agaagtgacg aatggtaatt
     3841 ttgatgtaca gctccccgta catgacaaag atgaatttga tgagttagca gatgatttca
     3901 ataaaatgac gaattcattg aaagaatctc aagcagaaat tgaagaacaa gaaaatcgtc
     3961 gaagacaatt tatggcagat gcttctcacg agatgagaac acctcttacg acaatcaacg
     4021 gacttctgga agggttagaa tacaatgcaa tccctgaaaa tcagcgagaa aacgcgatta
     4081 aattgatgaa aaatgaaaca gagcgtctga tccgtttggt gaatgaaaac ttggattatg
     4141 aaaaaatccg tacgaatcaa atcagtatgg tcattaaaaa attcaatgga acagaaacat
     4201 tgaaaaatat tgttgcacag ttagaagcta aagcagaagc agcaggagat acattgacat
     4261 tgaaagccgt tgatgatatt gatgtttacg ctgattatga ccgatttgtc caaatcatgg
     4321 tcaatattat tcaaaacgcg atacagttta ctgaaaacgg ccaaatcacg attactttag
     4381 aaaaaggcta tcttgaaacg atcatcacga ttgaagatac gggaattgga atgtctgaac
     4441 aacaaatgaa aagtatctgg gatcgttatt ataaagtaga tccttcaaga aaaaatacaa
     4501 aatatggtga atcaggatta ggtttaccaa tcgtgcagca acttgtacgc ttgcataaag
     4561 gaaaattaga agtagaaagc gaactaggaa aaggaacaaa attcgctgtt cgtttgcctg
     4621 acgtagaaat caaaaaagag taaaaaacaa gcggtataaa ag
//
LOCUS       DACBZK010000129         4662 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.135, whole genome shotgun sequence.
ACCESSION   DACBZK010000129 DACBZK010000000
VERSION     DACBZK010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.135"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            257..532
                     /locus_tag="IVD66_002690"
     CDS             257..532
                     /locus_tag="IVD66_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146856.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            545..2623
                     /locus_tag="IVD66_002691"
     CDS             545..2623
                     /locus_tag="IVD66_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAP6146857.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            2786..>4662
                     /locus_tag="IVD66_002692"
     CDS             2786..>4662
                     /locus_tag="IVD66_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP6146858.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     V"
BASE COUNT         1552 a          746 c         1005 g         1359 t
ORIGIN      
        1 tttttgtcgc agccccattt ttttgttgtg ataaaagaac aagaaaggca ggaatgggaa
       61 agtaaacatc cttttgtcag aaacttttat ctttcttaag ttttacttga tatctgatac
      121 tatttggaat agaatgaggc gttgaaaaat ttatggaaat ttctaactag caataaacga
      181 tgaaacaatg aaatattttt catccaaaaa gaactttgct ataatgatgg aagtttgtgt
      241 ataggagatc tggaaaatga gagagagttt tgaacaacaa aaaaaactgt tgcatgatcg
      301 ctatggcgcc ctttcgatgg atgaccgccg tcaaatactt tgtaagttgc gtaaaagaaa
      361 tatattgatg tatcgtcagt tggaacgtct gaaacatgat ctgcttcgtt tggagtcaaa
      421 acgtgtacag tgtgaattag aggggaacca aacacaggtt gaagtagtcg aaaccaaaat
      481 tttaaagaaa aaagaacaat ttttaaaaat gcttacacaa aataaaaaat aaaggggatg
      541 gacgatggaa tttgctgagt tagttattgt atttgcagta acgatcacct tatcgaacat
      601 agctagccgc attttgccaa tgattccagc tccactgatc caaattttcc ttggagtggt
      661 attaggtctg acagagtggg gacaatcaat cgattttgaa cctgaattgt tcttagttat
      721 gattattgca ccattgttat ttagagaagg agaaaaagca gatatttctt cgattctcaa
      781 aaatttcggg acaattttgt tcttggcatt tggaggagtc attttgaccc ttgtcggggt
      841 aggtgcgacg ttatcattcc tgttgccaag tgtcccactt gctgcctgct ttgcttttgg
      901 agcagcgtta ggtccgacag atgcggtagc agtcagttct ctttctggac gagtgaatat
      961 ccctaaaaag gcgatgcata ttttggaagg agaaggtctt ttgaatgatg catctggtgt
     1021 tactgccttc cagtttgctc ttggtgcgct gatcaccgga tctttttcag cagtaaacgc
     1081 ggggatgagt ctagtagttt ctagtattgg gggagctttg atcggctttt tgcttgtctg
     1141 gttcaaacaa aaaataattc atttgatcga aaaagcatca gcacaagatg tcacagggta
     1201 tctgctgatc gaacttttgc ttccttttct agcctatgta ttggcagagg catttgatgt
     1261 atctggaatc attgctgcag tggcagcagg tattctccaa gcttctggtt ttaggaaaat
     1321 ctctgtgttt gatgcagaat tgtcgagctt gtcccacagt acatggacaa ctattgcttt
     1381 tacactgaat gcattagtat ttatattttt aggaatcgaa ttgacgcaag tgttctcgcc
     1441 agtatgggga gacggtttat atccaaacgg tcttttatta gcgattatcg tattaatctc
     1501 tgtcatgctt tttgtgatca gattcatttc tatcagtctt ttttatgtat tcaaagatgg
     1561 cagtaaaaag ttcaaaaaac agttgaacga gatcttgatc ttaacatttg gcggtgtaaa
     1621 gggaacagtc agtttggcta cgatttttat tttgccattt tcaatcaata atatgatgtt
     1681 ttaccagcgg tctttgcttt tgtttctgac ggcgggtgtc atcttagtga ctttggtcat
     1741 agggatcatt gtcttgccta tgctgacgga aacagaggaa gcgaaaagca cggatttgaa
     1801 tgctttgatg attttagaag aggtcgttga agttttgcga aaagaaataa aggaaattga
     1861 tcgtaataca aaagaatttt tagccactga agcagtgata gaaaattatc aagaacggat
     1921 acgtgatctg tacttggaag atttaaccga tgatgaaaag caagaagtac aagaaataca
     1981 agcactgatt ttgtcgatcg aacgggatgg attggatgaa agttatcgtt cgggcaagct
     2041 ttcttctaat ggttatcgtt tttactcccg ttttctttct cgattcgaac attctatcac
     2101 aagccagatt ttgtctttta tcggcttttg gttcattgtt gtccgtaggt taatgcgaat
     2161 cgttctccat ccgaaaatgt tttggcaaag aagatatgct gatcgtcaga catttattag
     2221 tgatgaagat atccaagaaa tcagagagac atatcaaaaa aatactcagt tgattattga
     2281 aagtttagat aacttgactg atatttatga tgaaacgatg gttcaatttt ttatccagca
     2341 acgcaaactt gaaggaataa aaatgaactc ggggaatttg atttcttcgt ggatgatcca
     2401 gcaagatagt ctgtttacga aaaaaatgct aagaggttat tatcttgaaa gaaaaatcat
     2461 tgatgaatac gaagttgctg aaaaaatcac gacgttttct gcgaacagct atcgcaggaa
     2521 tatcaatttg ttagaatctt atacgatgaa caaaccatct gataactttt ctttccgatt
     2581 tgcgtttcga gcaaagtcaa aaaaaacgag tccaataaaa taaaaaggta aaaattttca
     2641 agttttataa aaaacaaaac atatcagaac aggatcgaat cggtcctgtt ctttttttga
     2701 gaacacaaaa agaacaaata ccaaaaaaat tttcctgaag ttcactattt ttatgataca
     2761 atatccaaga taaggaggga acatgttgaa agaattaaaa gtaactgacc tcaaaaaaac
     2821 ttatggtgaa aaagatttgt ttgaccagat ttcttttttg gtccacgaaa aagaccgtat
     2881 cgggttgatt gggacgaacg ggacgggtaa aacaagtctc ttaaatatta ttgccggtat
     2941 cgatagcagc gacggtgatc ggcaaacagt gttttatcca actgattacc gtattggtta
     3001 tctttctcaa gcagctgaat tttccgatga attaactgtt ctccaagcag tctttcaagg
     3061 aaacagcccc ttgatccaaa ctgttcgagc atatgaggaa gcattgatcg aactagggga
     3121 aaacggagaa gaccctgatg tgcaaaaacg ttatgctaaa gcagaagaac aaatgaataa
     3181 agaagatgct tggactacag ataccaacgc aaagattatt ttgcaaaaat taggaatcag
     3241 tgaattagat aaaaaaatca gtactttatc aggtggtcag aaaaaacgag ttagtctggc
     3301 gcaagtgttg attgatgaac ccgatttact attactagac gaaccaacaa accatttaga
     3361 ttatgaagcg atcgagtggt tggaaaacta tttgaaacaa taccgtggcg cactattgat
     3421 ggttacccac gatcgttatt ttctagatag agtagcaaac cgaatcttcg aactttcatt
     3481 tggaaaatta tacgagtata aaggaaatta tgaagcttac gtcttagaaa aagcagaacg
     3541 tgatcgtgta gaagtagaac aagaagaaaa gcgcaagcgg ctttataaac aggaattagc
     3601 ttggatgagg gctggcgtac aggcacgtgg caccaagcag caagcacgga tcaaccgttt
     3661 cgaagatcta aaggagaact tgtaccaagt aaaccaagaa gatgatttag agctgaacct
     3721 agcgacacaa cgtttaggga aaaaagtact ggaaatcaaa gatggcagtt accgtataaa
     3781 tgaccaaaca ctgctagaac atttagattt attgattcaa tctcgggaaa gactaggtat
     3841 tactggtaaa aatggtgcgg gaaaatcgac attgcttaat attctagctg gcagaattcc
     3901 cctggatagc ggtacaatgt ctatcggtga aacggttcat cttgcgtatt atacacaaga
     3961 aaatgaagaa atggcaccag ataaacggat gattgcttac ttacaagaag ctgctgaaga
     4021 agcaaaaaca gcagatggca gtcaaatcgg agtagcagaa ttacttgaac gatttttatt
     4081 tccaagattt atgcatggga cactgatagg caaactttca ggcggagaaa aacgccggtt
     4141 atttttgttg aaactgctga ttcagcaacc taatgtttta ttattggatg aaccgaccaa
     4201 tgatttggac atagcaacat tgacgatttt ggaagattat tttagaagtt ttccaggtgc
     4261 tgtgatcact gtttcccatg accgttattt cttggacaag gtagcagata agttattagt
     4321 attccaagga aacggaaaac aagaacttta ttacggaaac atgtccagtt atttactgaa
     4381 gcaaaaagag acccagcagc ctgctgaaaa agcgaaacca aaaatacaga gcaaggaacc
     4441 tgctgaaaag aagaaattat cttacatgga acaaaaagaa tgggaaacga ttgaagatga
     4501 gattgcagaa cttgaagaaa aaatctcatt gctccaagaa gagatgaatc atcaaggaga
     4561 taatttcact cgattacaag aattgcaaaa cgacgtatct gaaacagaag cacaacttga
     4621 agaaaaaatg gcacggtggg aatacttgag tgaatgggta ga
//
LOCUS       DACBZK010000130         4618 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.136, whole genome shotgun sequence.
ACCESSION   DACBZK010000130 DACBZK010000000
VERSION     DACBZK010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4618
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.136"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(15..962)
                     /locus_tag="IVD66_002693"
     CDS             complement(15..962)
                     /locus_tag="IVD66_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAP6146859.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(1140..1943)
                     /locus_tag="IVD66_002694"
     CDS             complement(1140..1943)
                     /locus_tag="IVD66_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HAP6146860.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            2089..3003
                     /locus_tag="IVD66_002695"
     CDS             2089..3003
                     /locus_tag="IVD66_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAP6146861.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            3051..3521
                     /locus_tag="IVD66_002696"
     CDS             3051..3521
                     /locus_tag="IVD66_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HAP6146862.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            3606..4214
                     /locus_tag="IVD66_002697"
     CDS             3606..4214
                     /locus_tag="IVD66_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HAP6146863.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            4348..4548
                     /locus_tag="IVD66_002698"
     CDS             4348..4548
                     /locus_tag="IVD66_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP6146864.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
BASE COUNT         1512 a          716 c          912 g         1478 t
ORIGIN      
        1 attgttttca gctattaata tcctgcagac aattttactt gattggtttg aagctcatgg
       61 gtggcaaagt agcttttcag attggttaaa aaaatagcca ttaatttctt ttgaaaatca
      121 ggtgtcaaac ctgcaatgtg ggaagtaatc agtacattgt ccattttcca aagaggatga
      181 tcttgtggaa gaggctcttc ctcaaaaacg tctaatgctg caaaggaaag ttgctggtta
      241 tttaaagcct gcaccagatc ttgtgtctta acagaagcac cacggccaac attgatgaat
      301 acagattttg gatcaaagtg ttcaaacata tgctgatcaa agagcccagt tgtttcctcc
      361 gttagaggta agatattgac tacgaaatct acttcaggaa gaacttcctt tagttgattt
      421 aaagaaaaag tcttttccat tccttctgct ggatgaccgg atgtattgat tccatagcag
      481 ttcatgtcta atgctttgca tttttttgca atcatttttc caatatggcc agttccaatg
      541 attagtattt ttttcccttg gatagattgg taatggaccg atgaacctaa ccatttcatg
      601 tcactctgtg ccttttgtgc ttgaaaaaga ccacgagaat acccaaggat gattcctaag
      661 acatgctccg taatcgattc actgtggatg ccactaccat ttgaaagtaa aatatgtttc
      721 tttgaaaaag tctcaagggg tagctgatca acaccagctg agatagattg gacccatttc
      781 aaggtagaag aggctaatag tttttcttgg tagtctgagt tccagcccaa actgatctct
      841 acattttgta gatcctctgg ttgtaattct gttttaaaga tataaccagg cgctatagta
      901 tggatttctt cgataaattc atcacgaaat ggacgatctg cataaatgat tctttctgac
      961 atagttaatt tcccgccttt ctttactcta agtgtagcgc atacaagaag aactttgaag
     1021 cgccttgctt gttttttgag aaagaaatat ttttcaaata aaaaaggggc tgtgacaaaa
     1081 aaatgtcaca acctctaaaa gggtctattg aagtagaaat aacgagttgt ctttatttct
     1141 taattgatcg atatttttgc ccatcctttg acagcttgag caaaaataaa gattcctgca
     1201 aaagcaatga aggcgctagt gtcaaaagaa ggaagaaaga ccatcaagat tgttgcaatt
     1261 atagtaggca atgaaattga atagatcaat gtttttaaac aatcaagaaa agtagctttt
     1321 gttagtcgaa agcgtgcata gagaaaagca gcaatgttgg taaatagcaa agtgatcagc
     1381 agattcagaa aactaggata aatagaaaat ataaatgtca ggacttttat ccaaagtggt
     1441 atagatgctt cacttaaaaa agaacggagc tgcttacctg ttaagttttt taaagattca
     1501 ttggtgtagg gaagttctaa ttggttattg ttcaacaaag cagaagtcgt gcctgtatta
     1561 ggaagagcta tgataagttt gttttttaac atcccgacac taacaaaatt ccccatcaaa
     1621 tcagtagaga tgtcctgttc tgttcgtttt ccctctggat caaatgtgaa gataatggag
     1681 tttgtttggt aaatgaatcc ttctttttct tcggtttgaa gctgcccgtt ttggattgta
     1741 aaatcaggaa tgcgagtagc aatcttttgc ccatccaatt gaatgttgtt taagacttga
     1801 aaaacttgaa aagagattgg caaagccata attatactca aaactaaaag atagacaatg
     1861 gctttccaaa atgggacatt tctcgcctcc tttaggtctt tgaatcgtat aaaggaactg
     1921 ataattaatt gttttgttgt cataagtact cctcatctag tagtgtcatc acttgcaatt
     1981 ctagcgaagt atcaagtgaa atacaagtgc tttaaggaaa cagctgaatg attggtgaaa
     2041 tatcaaaaaa atgttattct tgtctaaaga ctatccaata taaataaaat ggaggaagga
     2101 atagtgccta cacagccaca gagatcatca aaaaaactat ttggagtagt ggttttgaat
     2161 gcggtgatca ctttatcaga atttattgga gggattatgt cagggagttt gtctcttgtt
     2221 tcagatgctt tccataacct tagtgataca ttggcaatta ttttttctta cggggcacaa
     2281 aaaatggccc gaaaagaagc aaataaaaaa cgtacgtatg gctaccagcg tttagaaata
     2341 ttgagtgctt tcatcaactc attcatattg atcatattat ccttgttttt aaccgttgaa
     2401 gcattcaagc ggttcacttc accagaaaag ataaatagtc atttgatgct aacagtagca
     2461 gttattggat tgctcgcgaa tttgttctca gtattattat tacgacaaga agcagatgaa
     2521 agtttgaata taaaatctag ttatttgcat ttgttaagtg atacactgtc ttcggtaagt
     2581 gtgattatcg gagcaatttt gatccgtttt ttcgatatct actggatcga tccagttatt
     2641 acactgatca tttcgatata tatattgata gaagcgataa tggtgatcaa aaaagctgcc
     2701 gctattttga tacaaagtgc acctgctatc gactatgaaa aaatggaaca agaaattgaa
     2761 gcaatcgatg gggtaaagga tgttcatcat gtccatattt ggcagtatag cgaaaagata
     2821 attattttcg acggacatat tgattttgaa gatcagctac taagcgagat tgaaaagata
     2881 tatcctcgta taatttcttt attaaaatta aaatatggta ttacacatgt gacgatccaa
     2941 gcagagacaa aggcaaagga tcaaaaaaaa ttaatttttt taaataaaga tgaaagttat
     3001 tgaaatatag agtatgataa ataagaattt ttaataaggt aggttggctc atgaagcagt
     3061 atcgacagtt aaaaggatat ttagaagcaa aaggatattg ggagatacta gtctatctct
     3121 tttttggtgg tttggctacg attgtaaatt ttgttagttt tgctctcgca cgccaatatt
     3181 ttgatttaag tatggcctta tccaattcta tttcgtggtt ttgttctgta ttgtttgctt
     3241 ttgtaacgaa caaactttgg gtattccatt caaaatcacc gaattttaca catgcactta
     3301 ttgaatgcgg taagttcttc ttctaccgta tcctttctta cggattggac atgggggcaa
     3361 tggtattgtt gatcaatgtt atgaacagca atgagtatgt ggcgaaaatc atcactcaaa
     3421 ttattgttat ccttgcgaac tatattttca gcaagttgtt tatttttaaa gaaactgagg
     3481 tttttgaaga agaagtaggt caaagtgaaa aagacgacta ggcataacaa ttgaagaatt
     3541 tccttctctt tgttactctt tgtaatgtag acattattaa gaaaacattg aggaggaatt
     3601 tttttatgac ttacacatta ccagatctac cttatgcata tgacgcattg gaaccttata
     3661 ttgacgaaga aacgatgcat ctgcatcatg ataagcatca caatacttat gtgacgaatt
     3721 taaattcagc aattgagaaa tacccagaat taggcgaaaa aacaatagaa gaattattat
     3781 ctgatatgga cgctattcca acagatatca agacagctgt acgtaacaat ggtggcggac
     3841 atgctaacca ttcatttttc tgggaaatca tggcaccaaa tgctggtggc gaacctacag
     3901 gagaaataaa agaagcgatt aatgaagctt ttggtgattt ttcttctttt aaagaagaat
     3961 tcaaaaaagc agccgctgga cgatttggtt ctggatgggc ttggcttgta atggaaaatg
     4021 gaaaattagc tattacctct actgcaaatc aagattctcc attgatggaa ggaaagacac
     4081 caattctagg tttggacgtt tgggaacatg cttattattt gaaatataaa aatgtccgac
     4141 cagattatat tgcagcattc tggaatgtta ttaattggga tgaagtaaac aaacgtttcg
     4201 aagcagcaaa ataaccattt cctccgtcat atcagtctta aaaataattt ggaaaataaa
     4261 agagcgaaag cttgctagcg ttttctaaat tgggtataat gttcttgcaa ggttacttgc
     4321 aagaactttt ttggaggata tacatttatg gaacacggaa cggttaaatg gttcaacaat
     4381 gaaaaaggat ttgggtttat tacagtagac ggcggagatg acgtatttgt tcatttctca
     4441 gcaattcaag gagacggctt caagagccta gaagaaggtc aagaagtaga attcacgatt
     4501 gttgaaggtg cacgcggacc tcaagctgct gaagtgacta aattataata atttgttgaa
     4561 taaagacacg acttcttaga gagtcgtgtc tttttgtcta tttatgaagt ttttagat
//
LOCUS       DACBZK010000131         4480 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.137, whole genome shotgun sequence.
ACCESSION   DACBZK010000131 DACBZK010000000
VERSION     DACBZK010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.137"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            69..1370
                     /locus_tag="IVD66_002699"
     CDS             69..1370
                     /locus_tag="IVD66_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6146865.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            1373..2224
                     /locus_tag="IVD66_002700"
     CDS             1373..2224
                     /locus_tag="IVD66_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6146866.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            2237..3052
                     /locus_tag="IVD66_002701"
     CDS             2237..3052
                     /locus_tag="IVD66_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HAP6146867.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            3203..4369
                     /locus_tag="IVD66_002702"
     CDS             3203..4369
                     /locus_tag="IVD66_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP6146868.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
BASE COUNT         1351 a          812 c          856 g         1461 t
ORIGIN      
        1 tatcttgctc ttgttgccat tatcttaaaa gcagtttgcg gtttagcaag tttagagggg
       61 gcattcagat gcagcaagat aaaacaagca atatcaacga aaaaaaaatc acgctttgtt
      121 cacttattcc agggatgggg cagtttgtaa atggccaagc ttttaaaggt atcgtttttt
      181 tcgccatatt cgtcctattc attggtcaga tgcttctggg cggatttcat gcattggtag
      241 gattggttac tttgggaagt ataccaatgg aagatcattc attatttatt ttgattgaag
      301 gcactttgca attcatcatt acaatcattt tcttgatttt ttacggtttg aatcttttag
      361 acgcttatcg agtagcgaag atgcgtcaag agggcaaaaa aatcaatcgg acgatgaagg
      421 aagtcataca taatataggt gatgaaggtt ttccttatct attgacactt cccgcttatc
      481 ttctcatgat ttttacgatc attttcccag tcctagttac attgttcact gcatttacta
      541 attatgactt caatcatatt ccaccagcca gtttaattga ttgggtaggg gctaaaaact
      601 tttttagtat cttcttttta agctcatatc gtaatacttt ttttgcagtc ttttcgtgga
      661 ccgtgatttg gactttatgt gcaacaactt tgcaaatcac ccttggtatt ctcacagcgg
      721 ttgttgctca ccagaaattt attaaattca aacgtatttt cggtatcatt ttcttattac
      781 catgggcggt cccagctttt attactatca tgagtttttc gaatatattc aacgatagcg
      841 taggtgccat caatactcaa gtgattcctt tcataaacca gcttcctttt gtagatatca
      901 gtgcaatctc ttggaaaacg gacccgaact ggacgaaagt agcaattatc ttagtgcagg
      961 gctggttagg atttccctat atctatgtga tggttacagg aatcttacaa tcgatttcag
     1021 aagacttata tgaagcagca aaaatcgacg gagcaaatgc atggcagcgc ttttcaaaca
     1081 tcacgcttcc tgctgtcttc ctagtggcag cgccaacatt tattacacag tatacgggga
     1141 atttcaataa tttctccatg atctatctgt ttaacaatgg cggtcccgga agcgtaggcg
     1201 gaggagctgg ttctactgat attcttattt cctggatcta taaacttacg actggaactt
     1261 ctccgcagta ttctatggct tcagcaatca cgttgattat ctccgtcatc gttatctgtg
     1321 tgtcattgct ggtatttaaa aagacaaatg cgttcaatat gggggattaa caatgaaaaa
     1381 atttcattcg agtgctcgat tccaaaaacg actttctcac ttttttactt acttttttct
     1441 tttaatactg tcagtcatta tcatctatcc gcttttgatc acagcaagta ctgccttcaa
     1501 gtcaggaaat attgcagctt ttagtttaga tctttcaagt gactggactt taggaaactt
     1561 tactcggcta ttcagtgaaa cactttacgg gacttggtat aaaaatacat tgatcatttc
     1621 tgtcctaaca atgatcgtac aagtgactgt agtaactttg gcgggctata cttatagtcg
     1681 ctatcgtttt atcggccgca aatcaagttt gatgttcttt ttagtgattc agatggtacc
     1741 gactatggca gcattgactg ccttttatgt catggctttc ttattagaag cgctcgataa
     1801 gtactggttc ttgacaatga tctatatagg cggtggaatt ccaatgaata cttggctgat
     1861 gaaaggatac tttgacactg taccaataga tttagatgaa tctgctaaac ttgatggggc
     1921 agggcatttc aggatttttt tccagattgt attaccgctt gtcaaaccga tgctcgccgt
     1981 tcaagcatta tgggctttta tgggaccttt tggggatttc atgttagcta agttcctgct
     2041 tcgaacacct gaaaatcaga ctgttgctgt cggcttacaa acatttattt ctgatgtgac
     2101 aaaccaaaga gtctctcttt ttgctgctgg ggcaattttg attgcactac cgatttgtct
     2161 attattcttc tttttacaaa agaactttgt taccggcctg acatctggcg gaacaaaagg
     2221 ataggagcag agtatcatgc aaacatttcc gttaaactat ttttccgcat tacgtacgcc
     2281 aactcaagtg tttgcgggac gcaaactatt atcatggcct aaatttttct tgatatttgt
     2341 atttttagtt tccttgatgg tcatgcctgt gactcttttt tatgccaatc agatccaagc
     2401 gattccatta gaacaatttc tatccgttca ttcgctgatc gatgaacaag gaacccaaaa
     2461 attttctgaa cttgaattat ctgaaactgg gttacaagca tcgcaacaaa cgatagctgt
     2521 gacccctgaa attttggtag gtgtgtcttt atctgagaaa caacaatccg atcatggaac
     2581 ttttattgat tttgagaagg aacaatgggt gatccaacaa aaggataaat ctggtatacg
     2641 ccgctatacg atgaattata gcccatcttt ccaaccagat tctgtacgta cgcccgaaga
     2701 tttccaacga tttttagaaa gagaatttta tgccagtaat cgtccaacaa tcattttatc
     2761 ttatagttta agtcttggtc ttgtcctatt tgtcatgacg agtctcattt tattcggggc
     2821 ttcctttttc ttgtggatga caagaaaaag ccaactttca tccattcata cattcaaaga
     2881 gagtgcaaat ttgatgctga atgttatggg aataggttcc atggcagcag cagttgtagg
     2941 gtttatccac tttgacttta tcttgatgct aagtgtccaa acaacgataa ctgtcttgct
     3001 gcttttatgg gtttttgtca aaacaagatt caaagataag cgtgtcgaat gacaagttta
     3061 agcgatttat gcgacaatga atgtgaaaaa aatgaaaaat aaagtagttt ttgaaaaatt
     3121 tctgaaaaaa ttaaacttct tagttgattc ttttcttttt tagtattaac gtaatagggt
     3181 agttttttta aggaggaaaa tcatgttaga gaaaacttta tacaatcaat tattttcacg
     3241 ttctttctcg ctccctgtcg aagtaaatta ttgggacggt acaacgaaac aatacggaga
     3301 tacggacact cctccccaaa tcaaaatcaa tatccatgaa gaaatcccaa tgaaagagat
     3361 tacaagtaac gcatctttgg cactaggaga agcctatatg gatcatcgaa tcgagatcga
     3421 gggaagtatc caagcattga tcaacgatgc ttatcagcaa gcaaacagct ttttacgagg
     3481 aaaagattat ctaaaatggc tgccaaagaa agaaaaacat acgaaacaaa aaaacaaaga
     3541 agatatccat gcgcattatg acttaggtaa cgacttttat aaactttggc tagatccaac
     3601 tttgacttat tcttgtgctt atttcaatac acctgaagat acgttggaac aagcacaaat
     3661 caataaagtc catcatatct tagacaaact ctttatcaaa gaaggcgaaa cgttgcttga
     3721 tatcggttgt ggctggggaa cattgatgtt cactgctacc aaagagtata atgtcaaggc
     3781 aactgggatc acactaagtg aagaacaata cgatttgatt accaaaagaa taaaagaaga
     3841 acatttagaa gataaatgcc gtgtattatt aatggattac cgcgaactaa aaggcgaaac
     3901 gtttgatcat atcacaagtg taggtatgtt cgaacatgta ggttctgaaa atcttgaagg
     3961 ttatttcaaa gtggtaaaag atttattgaa accaaaagga acagctttga tccatggaat
     4021 cagccgacaa caaggcggtg cgacaaatgc ttggatcaat aaatatattt tccctggcgg
     4081 ttatgtccct ggtgttactg aattagttga taatattaca aaaaacgatt tgcaactgat
     4141 tgatttggaa agcttacgtc gtgactacca attgacatta gaacattgga caaagaattt
     4201 tcatcaagtc caagatcaag tcacgaaaga aatgggtgat tccttctatc gaatgtggga
     4261 tctatattta caagcttgtg cagcttcatt tgaatcaagt aatatcgatg tgattcaata
     4321 tttgcttgtt caacctggaa acaatgacat cccaatgcat cgtgcataat tgaggcaaaa
     4381 gtactgttta aagactattt aaaaagaagc taagttttat gatgctccag aagtgaactt
     4441 ttttgtctaa cttctaggat tgtctctaaa gcttagtttc
//
LOCUS       DACBZK010000132         4468 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.138, whole genome shotgun sequence.
ACCESSION   DACBZK010000132 DACBZK010000000
VERSION     DACBZK010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.138"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(462..887)
                     /locus_tag="IVD66_002703"
     CDS             complement(462..887)
                     /locus_tag="IVD66_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146869.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            1261..2232
                     /locus_tag="IVD66_002704"
     CDS             1261..2232
                     /locus_tag="IVD66_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6146870.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            2264..3661
                     /locus_tag="IVD66_002705"
     CDS             2264..3661
                     /locus_tag="IVD66_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP6146871.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            3820..4443
                     /locus_tag="IVD66_002706"
     CDS             3820..4443
                     /locus_tag="IVD66_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146872.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
BASE COUNT         1565 a          717 c          911 g         1275 t
ORIGIN      
        1 aaaaattact acgtgatgta gaataagcct ttctatcgtt tggttatttt atattcaaat
       61 atttgaaata aataaatctt tactctttga tttgtaaact gaaatgatcc actgtttgtt
      121 ttactgatga agcttgatca aaggaagaag ctgagtttga agttcataaa aatcagccat
      181 agtgagtttt gcttggattt gtttatcttc ttctactttt tacataattt tgaacaggat
      241 aagattcaaa tgttttaaat gaatctttga ctagtttgtg acagttgtcg catatgctca
      301 agcttccttg gtcattaaat tctgtatgga tatttttgtt gttattacat gtacaataat
      361 caggactatc gatcatccat ttcgtctcct ttacaatcat cttgcttctt tactatagca
      421 gaaaagaagg ggagaaacaa aagaagatcc aacagacggc actatagact gtagatgttg
      481 ccatcctcat ccttcaaacg gtaattaccg atttttgtaa atatgactgt tgtttctttt
      541 ttattttctt ttcctgaaat aatatattcg tcatctttgg tagtgatctt gatatctgtc
      601 agcactgttt tttcttcaga tgattcagaa gaatcagttc cttgtgtctg atacgtgcgt
      661 gtccattcca tttttttatc tgtaaatgtc aactgtcccg cggataaatc catatcttta
      721 cgtactttta gcgtatatac actgttggtg gtatctgctt tttccgcttt taagacagaa
      781 gaatcggttg tttcgtccga ggattggtca gagccgccaa acaaatcaca gccagtcaat
      841 gtcaaaagtc ccgcagacaa aataaatagt acgattaatt tcttcaaaat acttccccca
      901 tttgatagga taaagaaatt ataccattgg aatgtaaaac ttcaaacgga tggaagagaa
      961 aaacgcacaa aacacccaca aatagagtaa attttagaat aaaattttaa aaaggcaaaa
     1021 aatccgccac tttcagaaag cgttttaaaa aagtgttgca atcttttaaa aaaatgctat
     1081 attaaaaatg aaccggttca aatacttgtt taagtataat taatagtgag aggaagttgc
     1141 tctactgaag actttagtta tatggatatt gatgacaagc aacactatgc aaagaatgcg
     1201 gtcatcataa tcgaacaaca agaaagagaa atcaaatgta actggcagga gtgagaatgt
     1261 atggcatcga tccgtgatgt ggctaagatg gctggtgttt cagtgggaac agtttcccgt
     1321 tacttgaatg gtcagcaact gaaggaaaag aacatgaaaa aaatagcaga agcgatttca
     1381 gcgttggact ataaagaaaa catcattgct aaagggttga agaataatcg aagcttctct
     1441 attggacttt tgataaacgg gatttccagc cgttttgggt cggaagttgt ctcagggatc
     1501 gaaagagtag ctgaagaaaa tgggtatagc ttattattaa gcgggtttgc cgatcagcca
     1561 gaaaaaattg aacaaaaaat tgaatacctg atgaagcatg tgatcgatgg gctgattgtc
     1621 ttcttatccg aagaagagtg gtctggattt gaaatgctca caaaaatgag tattccagtt
     1681 atcgcattga attgtccaga aggaccagca ggtattgata caatattagt gaatgatcga
     1741 gaaagtgtag caaaagtgat cgctcatcat ggtgaacaag gacataaaaa aatcggattt
     1801 attgctgcca ctcaaacaga ctacgtagca agagaacgtt tagcaggagc caaagaagcg
     1861 gtccaaaatg atccatcgat ccaattagag gtctttacag gagactattc tagaaaaagc
     1921 ggctattacg gggcaaaagc attattagaa aaaggggcaa ctgctatttt tgtcagcaat
     1981 tacaatatgt cgattggtgc catcgaatgt ttcaatcaag aaggtgtcag aatcgggaag
     2041 gatattgcgt tcagtcacta tgattattta gataaaaacg atctgagtat ccttccgaaa
     2101 atcacgatca cgccaccaac agataaaatc ggggaacgag cagcagaaca gctgttaaaa
     2161 cgaatcaaaa aagaagagga agaaaatgaa aaagtgattg tgatggaaaa tatcatacat
     2221 ggaatcaact aaaacgaact aaaaaagaaa aagaggtgct ttgatgaaaa aatatcaatt
     2281 tccagcaaat ttttggtggg gttctgcagc aagtggccca caaacagaag gaaggatttc
     2341 aggcgatgga aaaggagaga acatttttga ttattggtac aaaaaagaac cgcaaaagtt
     2401 ctttgatcaa gtaggacctg aaaaaacctc gcaagtttat acgaagtatc aagaggatgt
     2461 acagttgatg aaacagactg ggcataattc atttcgaaca tctatccaat ggagccgttt
     2521 gatacctgat gaatctggaa caatcaacga agaagccgtt cgtttctatc atcgttattt
     2581 tgatgagttg attgaaaacg gtatcgaacc ctttgtgaat ctgtatcatt tcgatatgcc
     2641 gatgtatctg caagaaaaag gcggatggtt gaaccgagaa acggttgaag cctatgaaaa
     2701 atatgccaaa agttgttttg aattgtttgg ttcgaaagta aaaaaatggt ttactcataa
     2761 tgaaccaatc gttccagtcg aagcaggtta tttatatcga tggcattatc cagaagagtc
     2821 agatatgaaa aaagcgatcc aagttggcta tcatgaagcg ttggcttcag cgttagccat
     2881 caaatcttac catgaaatgg agcaaggtgg tgttattggt atcatcttga atctgacacc
     2941 aagctatcca agagacgaat caaaccctga agatgttaaa gcagcgcaaa tagcagatgc
     3001 gttcttcaat cgttcattcc ttgatccagc tgtaaaaggc gagtttccaa gtgaattgat
     3061 tgagatagta aaagaacttg atctcatgcc tgtgatccat gcagaggatt tgacggttat
     3121 caaagaaaat acagtagatc ttttaggtat caattattac cagccacgcc gggtaaaagc
     3181 aaaagaaaca ccaatcgata ctaaaaacgg tccaatgcct gaggattatt tcgacaatta
     3241 tgaaatgcct ggtcgtaaaa tgaatcctta tcgcggatgg gagatctatg aacaaggaat
     3301 ctatgatatt ttgatcaatg tacgagatca ttatggaaat atcgactgct ttatttctga
     3361 aaacggtatg ggtgtagaaa acgaagcacg atttatcaaa gaagatggca tgatccacga
     3421 tgattatcgg atcgaatttg tccaatctca tctgaaatat gtccatcaag ccattcaaga
     3481 aggtgccaat tgtttaggct atcatatgtg gacatgtatg gataactggt cgtggaccaa
     3541 tgcatataag aatcgatatg gctttatttc agtagactta gcacaagatg gaaaaagaac
     3601 aatcaaaaaa tcgggtcatt ggttcaaaga cgtatcagat aaaaacggat ttgaggctta
     3661 agaaagaata gttgagagca aatgcgtgaa attctccatt cttaccattt tgtgaaaaag
     3721 aagttcaatt atttacgatc tttttcaact tttttgtctt tctatttcat tttttgtata
     3781 taatagaata gtcaaaatta aataggagtg gaggaaagca tgaggaaaaa aagaccgttt
     3841 cttctctttt ggttattcgg ttttttctta ctgcttattt tatccgcagc attttcagga
     3901 aaaatgacag cagatcttgc tcagaaagaa acagaaaaaa tcgtagcaag caaagaatca
     3961 gtagataatt tcaaaaaaga attctcaact tattggtggg cggagtataa aataactgcc
     4021 aattacgaaa aaggcgaatt ggacatttat ttgccaaaag gaaaagaaga aaatcaattt
     4081 attaatatcg atgacgtact tagtgcgatt tctctcagac aatatcaatt taaagacaag
     4141 catttgaccg ttttgctttt gactcatgat ggcgacaaag tagcccgttt gaaaaatgga
     4201 aaagtgatca ccgcttattc tgaaaaagta gacaaaaaag tggtcgccga tcgtttagcg
     4261 gaatggaaaa agacaaatga acaagtcaag aaaacaactg tctcttctca aaaaaacgag
     4321 tcgacaggaa caagtccttc agattctggc agtggacaaa cgataacggg aagtgaagaa
     4381 aatcaagcct caattattac gaatgagtca tcacaaggac aatatcaatc ctatggacaa
     4441 tgaaaaacag aggttgtgaa atcagcgt
//
LOCUS       DACBZK010000133         4449 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.139, whole genome shotgun sequence.
ACCESSION   DACBZK010000133 DACBZK010000000
VERSION     DACBZK010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.139"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(452..793)
                     /locus_tag="IVD66_002707"
     CDS             complement(452..793)
                     /locus_tag="IVD66_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP6146873.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     KKSDQIKRVYFPIAEWEKAGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSASDTKKL
                     NRFIEKLQRKV"
     gene            complement(783..1064)
                     /locus_tag="IVD66_002708"
     CDS             complement(783..1064)
                     /locus_tag="IVD66_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HAP6146874.1"
                     /translation="MKVKNPTEKSRIQVGIDKNLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTKDMPVDVLDTDEKLEEWFDEA"
     gene            complement(1435..1674)
                     /locus_tag="IVD66_002709"
     CDS             complement(1435..1674)
                     /locus_tag="IVD66_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146875.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEDLLRKTQRKGYPDKILKQIGYYM
                     PEERIEKEFCEVLFDSEQLLVLLTQNKLICQFENN"
     gene            complement(1694..1942)
                     /locus_tag="IVD66_002710"
     CDS             complement(1694..1942)
                     /locus_tag="IVD66_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146876.1"
                     /translation="MEGMDFLDHEDLVDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDDTESLVDEEYKLDLENVLYGIEKEDLAKYIFLWLGQ"
     gene            complement(1957..2523)
                     /locus_tag="IVD66_002711"
     CDS             complement(1957..2523)
                     /locus_tag="IVD66_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146877.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTINGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMEKENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGADDCVAYYTTAE"
     gene            complement(2524..3069)
                     /locus_tag="IVD66_002712"
     CDS             complement(2524..3069)
                     /locus_tag="IVD66_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146878.1"
                     /translation="MGERTQALITVKYGNSKTKASVSIHYQWGYGRYMLMDVLNQGIY
                     LINKAYDLRDKSREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            complement(3095..3862)
                     /locus_tag="IVD66_002713"
     CDS             complement(3095..3862)
                     /locus_tag="IVD66_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAP6146879.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
BASE COUNT         1269 a          925 c          571 g         1684 t
ORIGIN      
        1 gttggttgag ttgtggctcc tattcaaaat tcactaatct gttatttttt atttctattc
       61 aagtaggtaa cgttcgtttg caagcaaact ctctctatgt aacttgccag ttacatcagc
      121 ggtaacgcta cgtcgcaagc gatttgctct aatgaaactg ccgtttcatt ctgcctgttc
      181 gttcgtagca agctacttca ctcactgtat ccgtctgaat tattgttatt tattgctatt
      241 caatatccgt cagacatttt atttatttac atacattgta tataaaatat attttataat
      301 tcgtatatta ctaaatatca ctatttaaca attcttaacg ttttcttaat gtttataatc
      361 acgtatatat ttacgtatat tttcatatac ataaatacgt ttatataaac gtatatctta
      421 atatacatat aaacaaaaaa gaaaagcctt gttagacttt tctttgtaat ttctcgataa
      481 acctatttag ctttttcgta tcactagctg ataacatacc aacctttttg aatgatatgt
      541 tctctcggct tttgggaata gcctttaaag accctacgtc aatccatgat tgctttttaa
      601 gtcctgcttt ttcccattct gcaataggaa aatacaccct ctttatttgg tctgattttt
      661 tctcatattg acttgtgatt ccaaagaatt ctactctatc ttctttatca ctaaccacca
      721 aaataggtct tcttttacca ccatttttat ctgtaaatgc aacatagacc gttactatct
      781 cattaggctt catcgaacca ctcttctaac ttttcatctg tatctagaac atctactggc
      841 atgtccttag ttagctgttg caatctgatt ccttgcttct cctcttcact tagctttatc
      901 tctactggaa actcacctct agcgactact tgtttgtaaa gaattgttat tgctgttgta
      961 ggatttaaac ctagctcttc caatatcatt tctgcgttct cttttaaatt cttgtctatt
     1021 ccgacttgga ttctgctttt ttcagttgga tttttgacct tcatttcatc cactcctttt
     1081 gagtataaaa cactcattat ttctcaaatt gtccacattt atgattatat tatactctta
     1141 ataaactaca ttgcaagtaa tctaatcaaa ttaagatgct atatcatacg gtaattgaac
     1201 aaattgtcgc taacccacac atacggaatc gtaatgaatg aaaaaaagac aagcctattc
     1261 gcagtaggct tgtctttgtg cttctcttgt acaaaatctt cacatttgta aattaatttt
     1321 agcacctttg ttaggaaaga acaacttaaa tgagatgcta aagaattaat agttctcaat
     1381 ctagcatatt cacttaatac catcttatct tcattcatgg ttcaccacct catcttaatt
     1441 attttcaaat tggcaaatca atttattttg ggttaacaaa actaatagct gttcactatc
     1501 aaaaagaacc tcacaaaatt ctttttctat cctctcttct ggcatgtaat aacctatttg
     1561 tttcaatatc ttatctggat aaccttttcg ttgggttttt ctcaataaat cttcatcatt
     1621 tccaacataa taataagaac accattgcat acccttactt ttaaattttg tcatgtttct
     1681 atcttccttt cacttattga cccaaccata aaaaaatata ttttgctaaa tcttcctttt
     1741 ctattccata taaaacattc tctaaatcca atttatattc ctcgtcaaca aggctttctg
     1801 tatcgtcatc ataaagaaca tatactgcat aatttctttc gtaaaaggca ttagcaagac
     1861 ttctgctaat acctaccatt cctttccatg tataaccaaa atcaaccaaa tcttcatgat
     1921 ctagaaaatc cattccttcc atgctgattc acactcctat tctgctgttg tgtaatatgc
     1981 aacgcaatca tctgccccta ctaaccacac acaccaatct tcaatttcat catcgcttct
     2041 cttactcaat tcctctttgg tacaaaaaac tacttcacca ttttcttttt ccatctcata
     2101 atcttgtagc atgtattcaa accaacttct ttcggttgga aattctatct cgtggcaact
     2161 ctggcaaata aaatcaccat attcattgat tcggtagcaa ccttcatctt ctacaaattc
     2221 atgattacaa caaacacatc tagtacctgt taggacttcc ccattaatcg ttgttctaac
     2281 ggtatcttct cttgctacgt gttcactgct gacaagccaa tcaatgattt tctttgccaa
     2341 ttcttcatca gaatcggcaa agcctttaaa cgtgtttctc tttccttgaa agtagtattt
     2401 gcaacttgcg gtagtttcta tggttccata acttttttgg aataattcaa tcatttcacc
     2461 atcaatcact ttttgacttt tcgcttctaa attagggaac tggtcttttc ttttttcaaa
     2521 cacttatttc acgctctctt cttctaggtt tattccataa ttttctagca ataatctgta
     2581 tcccttaata aaatctttcg tagcaaactc ttttccgctt tcacaaaact tgtttagtcc
     2641 tatctgttga ccctcaaaat caaacaatcg caatctggtt ttatcatcta gactaaatcc
     2701 attttcatcg aacaccatct ctaaatgagc atagccatca ttgttatctg aaaacttcat
     2761 cacatcttca atcgtttctt gataaggttc atagcgccca ccaaaccctg tttcatcata
     2821 agcactcact ccagattcat aggtaacaaa attgataact cctgtacttc tatcaaagat
     2881 tccttttgct aattcttctc ttgatttatc tcgtaagtcg tatgctttat tgattaaata
     2941 aattccttga ttcaatacgt ccatcagcat atatcgacca tacccccact gataatgaat
     3001 cgacacgctt gctttcgttt tgctgttacc atatttgact gtaattaacg cttgtgttct
     3061 ttcgcccatc ttgttttcct cttttctcta atttttataa agaaccattt tcttgaaatg
     3121 agtaatagct tgtgttttta cttgttacga tgatatggtc taacaattca ataccaattg
     3181 tttttcctgc gtttttcaaa ttcgtagtaa aacttttgtc attttcactt ggaaattcat
     3241 atccgctcgg atgattatgt gatactgcga tttttgctga attgtttagc aaagctagtt
     3301 gaaaaatctc tcttggtatc gctactgatt gattaattcc acctttgaaa acttcgctat
     3361 aagcaatgac ctcattcttt gtattcagac acatcactag caaagattca ctagcattgt
     3421 ttccaattaa gttagtagca aagtttgcta gaccaaccga gcttgtgact ctataaaaac
     3481 ttctatcttc actgatatat ttttgttcga ttttcaagac attcttaatc aatccttcac
     3541 cttcattctc ggtcttgttt tcaacttcaa tagattcaag actgctattt cccatatcag
     3601 aacccaacaa agcatttctg aaatccaata ccttttcaaa gttatcagtc ataaccattt
     3661 cataggtgct attccattca ttcaaatatt tctctttgat gagaatgaac gctctcggtt
     3721 tacttctgcc aattctgata ttttgtgtat cgtgaaaaat atagttatca agtaaagtac
     3781 catcgtactt ttcatagttc ccactgatat ttgttaactt gtttaccatt tcttgattaa
     3841 cttctaaaat tctatctctc atgttgaacg cttctttctg tttttgattt ttggtttttc
     3901 aaaattcttt tttgtttgga ttgttttaga gggaggtggt tttttcttca tcgctatttg
     3961 gttttgcatt ttatgtttct tcctttcgtt catttattta tctttttcgc ctgtcttgcc
     4021 ttgtcgggag tgattagaat gcgttcttat ctgccggatt aatacaagtg tttaagtaaa
     4081 ttattttcgt aacgcttgcg tttagaaaaa aatttacgcc acttgtatta atccaaagat
     4141 gagataagct ctaaacactt ctgacaaggc aagacaggcg aaaaagataa tgggcgtaag
     4201 gaattataaa tggcaaaacc aaataaagag cgatgaattt caatgctttc aggcgtagct
     4261 tgaaagccta aaagtcttga agaatgaaag actttttacc ttcaaagcag acctagtaat
     4321 cttaaatagg cgatggctat ttaagattac ggtgttgacc cactaaataa acagaaatgg
     4381 aaccgatcaa gcaaaatcgg actaggcgat ggctaggacg gtttgcggtg gctttaggaa
     4441 acgttcatg
//
LOCUS       DACBZK010000134         4438 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.140, whole genome shotgun sequence.
ACCESSION   DACBZK010000134 DACBZK010000000
VERSION     DACBZK010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.140"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(99..1619)
                     /locus_tag="IVD66_002714"
     CDS             complement(99..1619)
                     /locus_tag="IVD66_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAP6146880.1"
                     /translation="MTKMESELLVQIKQLTQLLEIQQQENTLLREQIAEMNRRLFGRK
                     KETPPVDGQIDLLDDSTFNEPEHTGQESQEPITVSSFKRRKRKGLKALSLEGLPEVPI
                     HYELKGADCLCEDCGHTLHDIGATRLREEPLYVPAHIEKQVIYQHAYHCRECEALGET
                     KIKKAPVPKPLINNSLGSSSIVTQSIWEKFVKKVPAYRQEKEWHALGFPLDRKKITNW
                     HIKVSEMVLEPIYNCLHQELSNQEVLHADETSYRVLNTHKEKTFYWLYASGKSEEKQV
                     VLYEHANSRSVDEPKSFLESFSGFLHTDGYAAYGKLPVNNVYCWAHVRRKFFEALGKQ
                     PSPKSHAKIGLDFCDKMFRIERTFNKLSAEERFVARKETLQPVMTEFFHWCESFAYLP
                     KSQLGKAVQYAVNHKDGLQIVLLDGRLELSNNRAERAIKELVIGRKNWLFSKSLKGAR
                     SNGIILSIIQTAVANGLNIRKYLNHLFTEIPNLSSMTPEALRAYLPWNQQIQEICK"
     gene            complement(1862..2047)
                     /locus_tag="IVD66_002715"
     CDS             complement(1862..2047)
                     /locus_tag="IVD66_002715"
                     /inference="COORDINATES: protein motif:HMM:NF017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HAP6146881.1"
                     /translation="MPMLIDATALKHIFIVCGKTDLRKGIDGLAAFVIEEYDLDVYDQ
                     ALFLFCGTKKDRFKALY"
     gene            complement(2031..2213)
                     /locus_tag="IVD66_002716"
     CDS             complement(2031..2213)
                     /locus_tag="IVD66_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146882.1"
                     /translation="MNKKDIVPVQFSSAAQKSQIDTKPKLACRIKSEDKEIFIYNGMD
                     KYLLYTLLKELNANAH"
     gene            2454..2672
                     /locus_tag="IVD66_002717"
                     /pseudo
     CDS             2454..2672
                     /locus_tag="IVD66_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            3167..3766
                     /locus_tag="IVD66_002718"
     CDS             3167..3766
                     /locus_tag="IVD66_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP6146883.1"
                     /translation="MKTVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLADVLEISRGRVVVKDRLAMKEQKTAKHNSVYISNKLRKTILEYVQQEFPDQ
                     LLQQDFDGYLFPSRKGTNEPLNRQSLWRIIHDAGTAIGLKDIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            3830..4429
                     /locus_tag="IVD66_002719"
     CDS             3830..4429
                     /locus_tag="IVD66_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146884.1"
                     /translation="MSTLYIIGNGFDLSHGLKTRYTDFSKWVEKSHSEIFDKIDTMIN
                     ENNEVRSTADDKIGWFNFESSLHELIQSPVFEDYVEESKDYLIGYGHEDWSDSAHHDF
                     QNMVYDYVVSLEELQQLFKEWIRKEIQPTIEHKIPKYQFSSDVLFFTFNYTDVLEILY
                     KQPKENIYHIHGSYDDIIIGHSENFDNFIGDPVLLQSFK"
BASE COUNT         1418 a          803 c          791 g         1426 t
ORIGIN      
        1 ataattcagt agttttgagc gtaagcgtgt catagaatgg tacctaaaca caaatagccc
       61 gatttgatac actcaaatca ggttatttgt ggcttatatt atttacagat ttcttgtatc
      121 tgctgattcc atggcaaata agcgcgtagc gcttcaggtg tcatcgaaga cagattggga
      181 atctctgtaa aaagatgatt taaatatttg cggatgttta acccattcgc aacagctgtc
      241 tggataatac tcaatataat tccatttgat ctagcgcctt ttaagctttt agaaaatagc
      301 cagttttttc gaccgatcac taactctttg atggcacgct ctgctcggtt atttgaaagt
      361 tccaagcgtc catcaagcaa cacaatctga agtccgtctt tatgattgac tgcgtattga
      421 accgcctttc caagctgcga ttttggcaaa taagcaaaac tctcacacca atgaaaaaat
      481 tcagtcatca caggctgcaa cgtttccttc ctcgctacaa acctttcttc tgcgctaagc
      541 ttattaaagg tccgttcgat tcgaaacatc ttgtcacaga agtctaatcc tattttggca
      601 tgactttttg gggacggttg tttacccaat gcttcaaaaa actttctgcg aacatgcgcc
      661 caacaataaa cattgtttac cggcagcttt ccataggccg cgtaaccatc agtatgcaag
      721 aaaccgctaa atgattctaa aaaacttttt ggctcatcaa cggaacgcga atttgcgtgc
      781 tcgtagagca caacttgttt ttcttcgctt ttacctgaag catataacca gtaaaaggtc
      841 ttttctttat gagtattcaa tacccgatag cttgtctcat ccgcgtgtaa gacctcctga
      901 ttgcttaatt cttgatgaag gcaattgtag attggctcta aaaccatttc acttaccttg
      961 atatgccaat tagtgatttt tttacgatca agagggaaac caagtgcatg ccattctttt
     1021 tcttgtcgat atgccggcac ctttttaaca aatttttccc aaatactctg tgtcacaatt
     1081 gaagaggaac ctagactatt attgatcaac ggtttaggaa caggcgcttt tttgattttt
     1141 gtttctccta atgcttcaca ttctctgcaa tgataggcat gttggtagat gacttgtttt
     1201 tctatatggg caggaacata caatggctct tctctaagcc ttgtcgcacc gatatcatgt
     1261 aaagtatgac cacagtcttc acacaaacaa tcggcacctt ttaattcata atgaatagga
     1321 acttcaggca gaccttctaa tgaaagtgct ttgagtccct tgcgttttct gcgtttaaaa
     1381 gaagataccg taatgggttc ctggctttct tgtccagtgt gctctggttc attaaaagtt
     1441 gagtcgtcta ataaatcgat ttgcccatct acgggtggtg tttctttttt tcgtccaaac
     1501 aagcgtcgat tcatttcagc aatttgttct ctaagaagag tattttcctg ttgctggatt
     1561 tcaagcaact gtgttaattg cttgatttgt acaagaagtt cagattccat ttttgtcatt
     1621 tttacaccac cattctagcg attttcttac atctattata ccattttatg acaacgaaaa
     1681 acagacaaaa tccttgattt aacaaggttt tcgtctaata tatcgcacct tttttcgttt
     1741 cttttagcgt acatttttct tcgattgaaa ggccagtcag taagacttct tttctggaac
     1801 gcggccattg aaggtaccca ctttcaaatc ttttgtacat taatacaaat ccattttgat
     1861 cctagtaaag agccttgaag cgatctttct tcgtaccgca aaataagaaa agcgcttgat
     1921 cgtaaacatc aaggtcatat tcttctataa cgaaagctgc tagtccatca attccttttc
     1981 gaagatctgt ttttccacaa acgataaaaa tatgtttcaa tgcagttgca tcaatgagca
     2041 ttggcattca actcttttaa caaggtatac aaaagatatt tatccattcc attataaata
     2101 aatatttcct tatcttccga tttgattctg caagctagtt ttggcttggt gtcaatttgc
     2161 gatttttgag ccgcacttga aaattgaact ggtacaatat cttttttatt cattcgtttt
     2221 tctccttcta tatttgatag tttaattata gaagaaagat aatcggcgta cgagatacta
     2281 tcctatgaca cgcttacatt taatttaata ttttgcctca aattagccac actttttata
     2341 gaactaagag gaaaaatgaa gttttcttcc tattaatata gttgtttgaa atcttaaata
     2401 tagcgtttta cgatgtaatg ggaagtatgg tgaataaatc aactatgttc gtacgaagca
     2461 tttactcaac taatttaatc gaatctttca ataaacaaat caagaaatac agccaccgca
     2521 aggaacagtt ccaaaatgaa gagtcgatgg aacgtttctt agtctcgtct tttgatactt
     2581 acaaccaaaa attcctaggt cgcagtcata aaggtttcca acaggccgaa ggcgagctcg
     2641 aacaaatgct gagtcaaccg atggagaatt agaaacaatc tacagtaggg aagaaccatt
     2701 gacacaaaat tattgacgct cccaactaaa agtgtcaaaa taatgatgaa atcatttagt
     2761 tcttataaat tagaaaagag aaaataaata ttccatatct actttattgg atccgtaaca
     2821 tgactaaatt ctgaatactt tttaaagctt atcatttggt aaaactgaat ataagttaat
     2881 tatatagact gaaaattttg aattttcaga atagaataac ttaaaagtac tgacaaaatt
     2941 ttttaaaggg gcaatattaa tgttctgaga taatcaaatc ctaccgaaaa tatcaaaaat
     3001 ccaatgtgac acaatcagat tgtgtctcat tcgagggaat cacacaatcc cacgtggctc
     3061 taggcagaat tgaatttttg cttggggctt tttccttata ttgattttga atgagactta
     3121 ttatatgtta taatgcaatt aagtatcatt ggagagggcg aagaaaatga agacggtaga
     3181 acctattcga gacaaaaaaa agatcgatgc gatgaaggca atcttggctt cgggaaaata
     3241 tggccaacga aatttggttc ttttttcgat tgggatcaac accgcctatc gcatttctga
     3301 tttgcgtcaa ttgaagctgg ccgacgtgct ggaaatttca cgcggtcgcg tggtggtcaa
     3361 agatcgatta gcgatgaagg aacaaaaaac agctaaacat aattcggtct atatttccaa
     3421 caaattgcga aaaacgattt tggagtacgt tcaacaggaa tttcctgatc aactccttca
     3481 gcaagatttt gacggttatt tgttccctag tcgaaaaggg acgaatgaac cgctcaaccg
     3541 ccaaagtctg tggcgaatca ttcatgatgc tggcacggca atcggattga aagacattgg
     3601 cccacattcc atgcgaaaaa cgttcggtta ctttctctat aaacagggga ccaaaacaga
     3661 aatcattcag tccttgttga accattcttc tcagcgcgaa acattgcggt atattggtat
     3721 tacacaagaa gacaaagata cagctgtaaa aagcttagat ttataatata aaagttaagt
     3781 ttaaacatgg atagttttaa attagtagat tgagtgttgg gaggaaagaa tgagtacatt
     3841 atatattata ggaaacggtt ttgatttaag tcatggttta aaaactagat acactgattt
     3901 ttcaaaatgg gttgaaaaaa gtcatagtga aatattcgat aaaatagaca caatgataaa
     3961 tgaaaataat gaggtgagaa gtacagctga tgataagata ggttggttta attttgaaag
     4021 tagtttgcat gagttaattc aaagtccagt ctttgaagat tatgtagaag agtctaagga
     4081 ttatctcata ggttatggac atgaagattg gtcagattct gcccatcatg attttcaaaa
     4141 tatggtttat gattatgttg tttctctaga agaattacaa caacttttca aggaatggat
     4201 acgcaaagaa atacagccga caatagaaca taaaattcca aaataccaat tttcgtccga
     4261 tgtactattc tttacattca attatacaga tgttttggaa attctataca agcaaccgaa
     4321 agaaaacata tatcatattc atggcagtta tgacgatata ataatcggcc actccgagaa
     4381 ttttgacaac tttataggag atccggttct gttgcaaagt tttaaataaa gaataaaa
//
LOCUS       DACBZK010000135         4432 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.141, whole genome shotgun sequence.
ACCESSION   DACBZK010000135 DACBZK010000000
VERSION     DACBZK010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.141"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            17..148
                     /locus_tag="IVD66_002720"
     CDS             17..148
                     /locus_tag="IVD66_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HAP6146885.1"
                     /translation="MILKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTAK"
     gene            394..990
                     /locus_tag="IVD66_002721"
     CDS             394..990
                     /locus_tag="IVD66_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP6146886.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPEKTLCDIWNPWYNVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            1003..1902
                     /locus_tag="IVD66_002722"
     CDS             1003..1902
                     /locus_tag="IVD66_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAP6146887.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNDIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            1905..2036
                     /gene="ssb"
                     /locus_tag="IVD66_002723"
     CDS             1905..2036
                     /gene="ssb"
                     /locus_tag="IVD66_002723"
                     /inference="COORDINATES: protein motif:HMM:TIGR00621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP6146888.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGN"
     gene            2058..2390
                     /gene="ssb"
                     /locus_tag="IVD66_002724"
     CDS             2058..2390
                     /gene="ssb"
                     /locus_tag="IVD66_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP6146889.1"
                     /translation="MIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEV
                     VADNFQLLESKAATESRAHADQSSTSPSTATFEQRNTATPNNNGLNASQNPFGGQSID
                     ISDDDLPF"
     gene            2435..2668
                     /locus_tag="IVD66_002725"
     CDS             2435..2668
                     /locus_tag="IVD66_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146890.1"
                     /translation="MDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVFVYLVCSYL
                     LKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(2827..2949)
                     /locus_tag="IVD66_002726"
     CDS             complement(2827..2949)
                     /locus_tag="IVD66_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HAP6146891.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            3139..3363
                     /locus_tag="IVD66_002727"
     CDS             3139..3363
                     /locus_tag="IVD66_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146892.1"
                     /translation="MIKTQPLLVRFTLRTSHEPINCVVANIEIADKLLILEEGKYTIS
                     VTGHFNKRKQLVIESMQIRNPDHFTRSMSI"
     gene            3806..4012
                     /locus_tag="IVD66_002728"
     CDS             3806..4012
                     /locus_tag="IVD66_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAP6146893.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            4012..4263
                     /locus_tag="IVD66_002729"
     CDS             4012..4263
                     /locus_tag="IVD66_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146894.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEVLLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENLETYENEYWLTKLEN"
BASE COUNT         1593 a          755 c          896 g         1188 t
ORIGIN      
        1 tgtacgtctg aagcctgtga ttttaaaagg tcagaagggt tcatttgaag caacgattgt
       61 tttaaaagaa gacttcacta caggctttga attttctgaa aagaaaaaaa cgaacttcaa
      121 gaaaagaaca cgccgcactg caaaataatg gagggttaat cttatgcgta ataccacaca
      181 caaacaacaa gaaatcgaaa atcaaaaagc caaaattcgt tcagaacagg aaaaaatgcg
      241 tgccagcaaa cgaagactgc agcaattgaa gaaccagcag aggattcaaa aagaaatcga
      301 attagatcga taaaatcttc ctaactattg tatacgtata aacttatgtt atactgtttt
      361 tataagttta tacgtataca aaggagggag aaaatgacaa aagcaatggt atacaagctg
      421 ctagaagaat ttaatggaac tttggctttg aaggatgcca aaaaagcggg catttctcct
      481 gtaacgatca aacgtatggt agatcgaggg gagctggatc gagagtatcc aggttttttc
      541 accttacctg gtcaatttcc tgatgaattg tttatggcgc aaaaaaaata tgaacgcggc
      601 attatttcac atattaccgc gttagatttg tatgatttaa cagatatgat ccctagacag
      661 atcgatctga ctgtacctta cggttatcac gtttctgaaa aaggattgaa ggaattcgca
      721 gttgagctac actatacaaa agcggaatgg tatgaattag gtaagattga aataaaaagt
      781 cgctatggga atcctattat agcttatgat ccagaaaaaa ccttgtgtga catttggaat
      841 ccctggtata acgttgagga tgaaatcaaa gtaaaagcaa tcaaaaacta catggagtcg
      901 gacagaaaaa atcttagaaa attgaatgag tatcgacgaa ttttgcctac agataaaacg
      961 atgcgctctt atattatggc tttaaattaa aggagaatac acatgacacc tacgcaatta
     1021 aaagcaaaag tgaagaatat ttctagagaa aaagaagttg atccgcagct tgttttaaga
     1081 cattttatga tggaaaaatt cttggaaaaa atctcagagt ctccttatcg tgaaaatttt
     1141 gtgttaaaag gcggcttctt aattggctca aagtatggca ttgaaaatcg aacaactaaa
     1201 gacattgata cgactttacg ggaaatgaaa gtaaccaaag aaacattgac aacggttcta
     1261 aacgatattt tttcaacgcc gacgaaagaa ggcattcaat ttgagattca aggaatgaaa
     1321 gaaacgaggg aagctgatta ttatccaggg tttagcttac gtgtactggc acatttggaa
     1381 aacatgcggc cagattttaa ggtagatgtt actacaggtg actcgatcta tcctgcgacg
     1441 atcactcaca gtcataaatt gatgtttgag gatcgaacga ttcctttgga atcctatcct
     1501 acagaacaaa ttattgctga aaaattaagt gcaacctttg attttttaac agataattcg
     1561 agaggaaaag atttttatga tctctatact attcctaaaa tggagaagat cgatgagaag
     1621 accttgaaag atagtgtgag aaatacattt acacgtcgag gaaaaactga tccgttaaag
     1681 atatactatg aaaaggatat ggatgtactg aaaaatagtc acgagctaaa agatacctgg
     1741 aagaaatatc aaaaaagcaa tccttatgct gcgtcgatca cgtacgatga gacaatggat
     1801 tcgattagta atttgatgga aaaagtgatt cacgtcgaag aaaaagagcg aaaactagct
     1861 tatcaaagac accaacagat gaatagagaa atggagagat aaagatgatt aataatgtga
     1921 cattagtagg acgcttaacc aaagatcctg atttacgtta taccgcaagt ggtactgcag
     1981 tagcgacttt taccctagcc gtcaaccgaa atttcacgaa tcaaaacggc aattgagaag
     2041 ccgattttat taactgcgtg atttggcgca aaccagcaga aacaatggcg acattagcta
     2101 aaaaaggtag cttgattggt gtagttgggc ggattcaaac gcggacttac gacaaccagc
     2161 aaggacaacg tgtatatgtg actgaagttg tagcagataa ctttcaacta ttagaaagta
     2221 aagcagcgac agagagccgt gcgcacgctg atcaatcgtc caccagtcca agcaccgcca
     2281 cctttgaaca acggaataca gcgacgccta acaacaatgg attgaacgct tcacagaatc
     2341 catttggtgg acaatcaatc gatattagcg atgatgatct accgttttag tttgagaaag
     2401 aaggagtaag catggcaaaa aaattagtct gacgatggat ctattgatac ccgtaattgc
     2461 atttatagac gggatttctt tgggcgtcac tgaaaatcct ttggtaaata gaattgcgaa
     2521 aggatcacta tttcttgtat tcgtgtatct tgtctgttct tatcttttaa aaagagcagg
     2581 aaaggataat tccttttggc gattgactaa agtcacagta gcagcgacag ctgttatact
     2641 tacggctatt ctaccgcttt atatgtagag ttaacgggaa atcgttgaac ttcttgcgaa
     2701 atattgctat aatgaacatg aaaaagagga gttgcgctaa caacccctca ttaacagcac
     2761 cgattaaaga acggtggcag aatattagtt atttggaaat aaccgctgac ctgctaaagt
     2821 agacggttat ttctttttgt catttttaag catatttaca atcaaactaa tcaaagcaat
     2881 ggtaaacata ccaaaaccaa gaatggtttg aattgtctca tatgcggaca aaaggcttac
     2941 tcctttcata gattttagca cttacattca taagcaccac cacctttcca gaagtcgcca
     3001 ccgtcttcaa actttactgt cttgactatt atagcatatc taaaatcgaa taaaaattct
     3061 caattttagc tgtttttgct ataattttag cgaggtgatc gtgatggaac aatatattgg
     3121 tttactcgat aaattagggt gatcaagaca cagccattgc ttgtgcgatt tacattacgc
     3181 acgagtcatg aaccaatcaa ttgtgtagtg gccaatatag aaatagcgga taaattgctg
     3241 attttggaag aaggcaagta tactatttca gtgacaggtc acttcaataa acgaaagcaa
     3301 ctagtcattg aatcaatgca aattagaaac cctgatcatt ttacgcgatc gatgagcata
     3361 taaaagaaga gctgcagtcc taaatgagga ttgtagctct ttttgtttta catagaaaca
     3421 gtaaaaatga aaaggcctgt ttaggaaggc acaagcgcct tctcaattga aagacctttc
     3481 tctcactcca accgccaccg ccgttcgaga agaaaggaag tgaacgctac gcgttcacta
     3541 agataaaggg tcttgcatag caagacaaaa tagaaaaaat ttcctctcac caaaaggttc
     3601 gctcctgttc gttatctctt tattgatttg tcagaccggc aacaagttgc cttttatcac
     3661 caaaaagcga caaggacaag ggtaaatggc acgctgcgcg cccttgtctt gtcgcttttc
     3721 gttgattcat tctggccaac aaatcaataa agaaagaact aacgaaagga agtaaaacct
     3781 ttcctaagag gaggcagaat caatcatgcg aaagaaattt gattattggg gtgttccctt
     3841 cagcgaatta ttcccaaact atcatgcacc acatactgtc gaatgcgatt gtggagaaag
     3901 agcgaaatgt atcaaaagct attgtttgta tcaatgtcca acatgcggga aaaaatatac
     3961 cttgtcttat ggcgattata ttttaattga tgagaaagga aagaaacgct gatgaaaaca
     4021 caacacaaat tattgactgt aaaagaagtc gttcaaattt tggtggacaa agaagtcatt
     4081 tctgaaaaag tagcagaagt tttacttatt ccgcggtact ggacgataga aaccccttta
     4141 gtagaggatg caccgactat gctatttgaa gacctagtga agattgcagg atatgaactg
     4201 cattatcaag aaaacttgga aacttatgaa aacgaatatt ggttaaccaa attagagaac
     4261 taaaaaggag aaaaaaatat ggctcaaaat tactatgacg aatttgtcaa attacctttg
     4321 gataaaatgg cacaaaaaat ggaggatatg acgttcctat acaacgaaac acgtgttcca
     4381 aaaaaacatt ataaagaaaa attgtcggta gctgtggaag aaatgattga at
//
LOCUS       DACBZK010000136         4431 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.142, whole genome shotgun sequence.
ACCESSION   DACBZK010000136 DACBZK010000000
VERSION     DACBZK010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4431
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.142"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(543..2048)
                     /locus_tag="IVD66_002730"
     CDS             complement(543..2048)
                     /locus_tag="IVD66_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP6146895.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="IVD66_002731"
     CDS             complement(2045..2731)
                     /locus_tag="IVD66_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6146896.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="IVD66_002732"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="IVD66_002732"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HAP6146897.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1239 a          919 c          729 g         1544 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat a
//
LOCUS       DACBZK010000137         4424 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.143, whole genome shotgun sequence.
ACCESSION   DACBZK010000137 DACBZK010000000
VERSION     DACBZK010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.143"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            690..1658
                     /locus_tag="IVD66_002733"
     CDS             690..1658
                     /locus_tag="IVD66_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP6146898.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADVRNHDLDVRRYMGKVEY"
     gene            1669..2484
                     /locus_tag="IVD66_002734"
     CDS             1669..2484
                     /locus_tag="IVD66_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HAP6146899.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            2552..3262
                     /locus_tag="IVD66_002735"
     CDS             2552..3262
                     /locus_tag="IVD66_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6146900.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            3298..>4424
                     /locus_tag="IVD66_002736"
     CDS             3298..>4424
                     /locus_tag="IVD66_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAP6146901.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIK"
BASE COUNT         1490 a          661 c          921 g         1352 t
ORIGIN      
        1 atacaaataa ttcaccaaaa aggtgagtaa tgccattttt gaaaattgag cttgttttat
       61 gtctacatct gtatccgtat ataatccaaa ggattataaa ctcagaagag tctttatttt
      121 ttctgaatat aactactgta tcaaaaacaa tcgattatga gacaaaacaa aatgacctct
      181 tttatttaag aaaggaggtc attttttgta tcataaattg tattaaaatc aatgtatcac
      241 tttttaatca gttttaagac cataaattgc gtactaaaag aaattctgca attcaaaata
      301 aagcatttta agccattttc aaatttaagt gcacccatct acccgtcaaa tcactttatt
      361 ttccactcca gtagtttcct aattcaactg tgtgcaaaaa cgatttcttc taaacaaatc
      421 aagacaaact tataaacctt catcccagca ccataattat ttaaatcata ggcatttttc
      481 gaaattagta tatgtactca agtttcactg cagattattt atatttttta gagaaataaa
      541 tttttcctat tgacaaacac aaagaaagcg gatacaatgc aattatgtca catgacgtta
      601 tatgacgtta tgtgatatct ttacatttaa tcagttactt ttattttgga taaaattaac
      661 atttttaaaa ttttaaggag gaaatgttga tggatgtagc aaaaacggtt aacgcaattg
      721 tagaaaaaaa tgatggagag atttctggaa tttatttggt ggcttgtggc ggttcgctgg
      781 tagatatgta tgtctcagat tattttctta aagccgaagc atcgaagtgt attacaggct
      841 tatatacagc gaacgaattt aaccatgtaa ccccaaagca attagatgat aaatctgttg
      901 tcattctatg ttctcatgga ggaaatacag cagaaacggt aaaagcagga gaagtcgctc
      961 aagctagagg agctgtgact gttggtctga ctcataataa aactgcggat ttattaaagg
     1021 tttctgatca tagtttcctt tacgaatggg gagatgatgc aaaaatagtc aataatccta
     1081 tggccatcat tcttgattta actgtatctt tggtcaatgt taccgaaaca tttgaacatt
     1141 acggtaaatt cagagaaggc atgaaggtta tcgataccgt aattgaaaat ggcattaagc
     1201 aggtgcagga tcgtattaaa gtgtttgctg ataagtacaa agatgaaaca atgttttata
     1261 tcttaggtag tggaccatca tatggacatg cttatggttt ttcaatttgc tctttgatgg
     1321 aaatgcaatg gcttgattca acttctgttc attctggaga attcttccat ggaccttttg
     1381 aagtaacaga caaagatacg aattttattc tcttgatgag cattggacgc actcgtgctt
     1441 tagatgaacg ggcaaaacga ttccttgata aatatgcaga aagagtagaa atcgttgatg
     1501 caaaggaact aggattggat atgatatcag atgaagtttc tgaattcttc aatcccattt
     1561 tattctacag tattctttca gaatatcgtt cagctttagc agatgtacgc aatcatgatt
     1621 tagatgttcg tcgctatatg gggaaagtgg agtactagga ggattaaaat gaaggtatta
     1681 ggcttaggtg ataacgtcgt cgataaatat gaaaatctgg gaattatgta tcctggagga
     1741 aattcattga attttgcagt ttttgcaaaa aaactgggac atgaaagtag ctttatggga
     1801 gtttttggct cagatgagga ggcagctcat gttttatcag caataaaaga aataggactg
     1861 gacaacagtc actctcgctt tgaaaaaggc gagaatggct gtgccagagt gaagattgat
     1921 gagggcgacc ggattttcct tggcagcaat tcgggaggtg ttactcgtga atacccgatt
     1981 cagcttactg aagaagacag agaatattta aaccagtttg aattgattca tatgggatta
     2041 tatagccatg tcaatcatct attagaagag ttacaaaatg tttctggaaa gatttcttat
     2101 gatttttctg acgactttac ggaagaagag gttcagcggg caattgataa agttgatttt
     2161 ggcttctttt ctatagaaga cttttccgat gaagaagtaa agcagttttt gatgaagcat
     2221 ttttgtgagc gaaatgatgt attgattgca acccgaggag aaaaaacggc tattggttat
     2281 gatggagcaa agttttatga agtgaacccc gtgctagaag aaccagttga tacaatggca
     2341 gcgggagatt ctttcttaac agctttccta ctttattttc tcgaagggga cgatatagtc
     2401 accgcgatga aaaaggggaa tgaatttgct gggaagtctt gtctggttga cggttcgttc
     2461 ggctttggta ttcattacga ttgagcttgt tttaaattcc tgcatttgat aacctaaaga
     2521 aagaaatccc ggtaaagtgg aggttaaaaa aatgctggat acaaatgcac aattaccatt
     2581 gtacttacaa ttaaaagaaa tattaaaaaa taaaatcaat acaggggagt atcccgagaa
     2641 tacgaaaatt cccgctgaat cagagctgat agaaagttat gaggtcagcc gaatcacagt
     2701 gagaaaagca gtagaagaac tggtagaaga agggtaccta cttaaaaaac aagggaaagg
     2761 aacttttgtc aaccggcata aagtttttcg taaaattgaa tatattatgg gtttcagtga
     2821 gagttgtaaa tctaatggtt ttacaccgac tagcattgtt ttggaacgca agatcattcc
     2881 agcaactgaa gggatggcaa aaaaactcga tatcgctcaa ggtgatgatg ttttatatat
     2941 ccagagaaag cgaatggcgg ataacatccc cattatgtta gaaaacaatt atttttctta
     3001 tgaaagatat agtttcttaa tggaggaaga gctgactgat tctttgtatg aagtacttaa
     3061 agtccaaggt accttagcca tcaatcctgg ggaaactgca cttgaaattg tcacagctga
     3121 tgaccaaatt gccaaaataa tggaagtagc tgttgggacg ccctttttct ttatggatac
     3181 tttaatcaac gatcaaaaca acataccaat tcatgtaggt aatcaatatt acctgggaga
     3241 agtatatcgt ttttacttat gatttcctgt ttggatttca aggagtagat tttatttatg
     3301 aagcaaatat tgcggtcaaa aatgattttt gatggagagc agccaccttt caaaggttat
     3361 attgtaatca atgaagggat cattgaaaag gtggaaaaca actggaatta cagtgatcta
     3421 ttaaatgaaa acacggaatt aattgcttat gatgatcaat tcgttatgcc agcaattcat
     3481 gataatcatg tatttttcag tggttatttg gctatgaatg ctggcataga tttaagcgat
     3541 acatcttcag ctaacgaggc tgtagagcgt attaaagctg taatgaacca taaaaaagca
     3601 gatgaaccaa tttatgctca tggctgggat gctgccctgt ggaaaactga cccatcagaa
     3661 gagctattga atgaaataaa ccactttggt ccaatcacag cgatcgacaa aaatcgcagc
     3721 cattgttgga tgaatgctat tgctaagcag acttatggtt ttacagaaaa agaaaccagt
     3781 gctgaaagtc gagtattatt aattaaggaa atgctagcaa acaaaaagct tttagcagag
     3841 gtttacgctg aatttgaagc attactgctt tcaaaaggtg ttatatcaat gaaagaaatc
     3901 gtttttgatg acgcagaatt tctttctaat atacctcaga ggaaaatact tagtaaccta
     3961 tatgtgcagg cagtccaaga acctctacag catgaacttc tatatgagta taaggaaaaa
     4021 gttttccctg aaaaggtccg ctttggtgga gtgaagatca tggtagatgg tgttgttgcg
     4081 gatagaagtg gagatattta cggtgtttat cagtcaggag tagcttcacc cgagattgac
     4141 tatgaggcaa ttaaagcaga agttgctgca ttcaatgaag tagagattcc ttgctgtttg
     4201 acaacggaag gagataaagc gggttataaa gctgcgtcaa ttcttgtcga atttggaaag
     4261 cggttacctg aaggcgtttt taattcgatt agtgatttgg aaatggttac tcaaaagaca
     4321 gcagaaaaaa tgaacgaagg acaagtagta gcagaggtat atccacaaat tctcggcttg
     4381 aatcaaacgt tagaagaggc ttacatgtca actgttataa aaaa
//
LOCUS       DACBZK010000138         4306 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.144, whole genome shotgun sequence.
ACCESSION   DACBZK010000138 DACBZK010000000
VERSION     DACBZK010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4306
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.144"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            149..1138
                     /locus_tag="IVD66_002737"
     CDS             149..1138
                     /locus_tag="IVD66_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HAP6146902.1"
                     /translation="MKKKKQDLINGTFREKKKNLKKVVAFSDNRISPRMRELMTGCGS
                     YLEFIATIDKEKKKLVQAHFCKNRFCPLCAWRKARKDSMMLSIMMQAIAEEKQYQFIF
                     MTLTTPNVKAERLNDEIDLFNHALSKMFRRKKVQIAIKGYVRKLEITYNKEREDYNPH
                     FHLILAVNKSYFTDKDYYIKQSEWLDLWREVTGKTGVNPDGTDEITQLDVRKVKGFQQ
                     EKAVQEVAKYSAKDFELTESQEVFDTFYHAMKGRQLITFNGVFKEYKKKYESGDLDRY
                     KKKDENEYFWFLTASWMRKESKYAVDYREMSADERNYFSGMYVDEKSVEGENE"
     gene            1135..1554
                     /locus_tag="IVD66_002738"
     CDS             1135..1554
                     /locus_tag="IVD66_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146903.1"
                     /translation="MTDSTDKMTIKALADELGITKNTVRNYLVKAGYDLARYKKNGII
                     LLDKELIGVARSIYRSKGGQLTGHLPVNSTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            1563..1871
                     /locus_tag="IVD66_002739"
     CDS             1563..1871
                     /locus_tag="IVD66_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146904.1"
                     /translation="MDKIDLREETVNRIEVMYERLADYLNLSDEDNYSEMLERMMDVL
                     NSVINADLAKSSVLTNEFVHKHLAQTTDEAEKEFWLKLMSHIMQLNQISVINSKEKGM
                     "
     gene            1875..2237
                     /locus_tag="IVD66_002740"
     CDS             1875..2237
                     /locus_tag="IVD66_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146905.1"
                     /translation="MGMTLADIKVQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFESFADFERWLSSISDDQQHEKSVGNELRADEKSAPSERNYPNESDGIFGGIPNRK
                     SQMSESGFASMFSDVNSR"
     gene            2459..3865
                     /locus_tag="IVD66_002741"
     CDS             2459..3865
                     /locus_tag="IVD66_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HAP6146906.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKINDWHKHIDFTKSDEN
                     IYLEQINIREKYEELFGEAVEKYNAKQKRADRKIEDYLAKVRKDKKMEPQREFIVQIG
                     TLDDFRTTRDDGSSTGISEQQAEQNRVIANKILVEYFKEFKERNPSLSVYNAVIHNDE
                     VSPHLHLNIVPVAEGYKRGVQKQPSFNKALQQQGLRADKENGRVIWNNFRNQEVESIE
                     RLMADFGWERELVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELRYICRQREE
                     NEREKALVASERAKIEEEKKNMLNVKKEMAVIFQKDMVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVAALEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQHKLERSEDEIEW"
BASE COUNT         1501 a          602 c          996 g         1207 t
ORIGIN      
        1 aaaaaaaaag attgcttttt cttccctagt gatttatagt tttaattgtc taagtcaaaa
       61 ctaaactaga aaggagagca atcttaattt ttgttatcgg cttttcagcc ttttttgtat
      121 acaaaatttg tagattcagt atagcaagat gaaaaagaaa aagcaagatt tgattaacgg
      181 aacatttcga gaaaaaaaga aaaatttgaa aaaagtggtg gcatttagtg ataatcgaat
      241 ttctcccaga atgcgtgaat tgatgacagg ctgtggttca tatttagaat ttattgcaac
      301 gattgataag gagaaaaaga aattggtcca agctcacttt tgtaaaaatc gtttctgtcc
      361 gttatgtgct tggcgtaaag ctcgtaagga ttcgatgatg ttgtcgataa tgatgcaagc
      421 cattgcggaa gaaaagcagt atcaatttat ttttatgacg ttgacgacac caaatgtgaa
      481 agcggaacgt ttgaacgatg aaattgattt atttaatcac gcattatcga aaatgtttcg
      541 tcgaaaaaaa gtgcaaatag cgattaaagg ctatgtgcga aaattggaaa tcacatataa
      601 caaagaacga gaagactata atccgcattt tcacttgatt ttggcagtaa ataaatcata
      661 tttcacggat aaggattatt atatcaagca atcggaatgg ttagatttgt ggcgggaagt
      721 gactgggaaa acaggggtca atcctgatgg tacagacgaa attacgcagt tagatgtccg
      781 taaggtcaaa ggattccaac aagaaaaagc agtacaggaa gttgcgaaat attcggcaaa
      841 agattttgaa ctgaccgaaa gtcaagaagt gtttgacaca ttctatcatg caatgaaagg
      901 tcgtcagttg attacgttta acggtgtatt caaagaatac aagaaaaaat atgagtcggg
      961 tgaccttgat cgttataaga aaaaagatga gaatgaatat ttttggtttt tgactgcttc
     1021 gtggatgagg aaagaatcga aatatgcggt tgattatcgt gagatgagtg ctgatgaaag
     1081 aaattatttt tcaggaatgt atgtcgatga aaaatctgtt gagggggaaa atgaatgact
     1141 gattcaacgg ataaaatgac aattaaggcg cttgctgatg aactaggaat aaccaaaaat
     1201 acagtgagaa attatctagt caaagccgga tatgatcttg ctcggtacaa gaaaaatgga
     1261 attatcttgc tagacaaaga gttgattggt gttgctcggt caatttatcg gtcaaaaggt
     1321 ggtcaattga ctggtcattt accggtcaat agcacgggca gtgattttcc tttggaaaaa
     1381 gagaatgagt ttttgcgtga tcaattagct gagaaggaca aacatatttc tgaattaaca
     1441 gaaatgattc gtgatcaaca aaaattgacc ctgcttcagc aacaaaaaaa cgatcagttg
     1501 ttactagaaa atcaagaatt aaaaaatcga aaatggtggc aattctggaa gtgagatgtg
     1561 acatggataa aattgatttg agagaagaaa cagtcaatag aattgaagtg atgtatgaac
     1621 ggttagctga ttatttgaat ctttcggatg aagataatta tagtgagatg cttgaacgaa
     1681 tgatggatgt tctcaactcg gttatcaatg ctgatctagc aaaatcttca gttttgacta
     1741 atgaatttgt tcataagcat ttagcgcaaa caactgatga agctgaaaaa gaattttggt
     1801 tgaaattaat gagtcatatt atgcagttaa accaaatttc cgttattaat tccaaagaaa
     1861 aggggatgta gtttatggga atgactttag cagatattaa agtgcaagaa gaaaaattaa
     1921 aaaaagaaca ggcgaaactt cgccaacaga agaaacgatt gattgagaaa gaaaatgctg
     1981 caatgggcaa ggctcttcgc aagcgttttg ggtttgaatc ttttgctgat tttgagcggt
     2041 ggctatcgtc gatttctgac gatcagcaac acgaaaaatc agtgggtaat gagttgcgag
     2101 ctgatgaaaa atcagcacca agcgaacgga attaccctaa cgaatctgac ggaatattcg
     2161 gagggatacc gaatagaaaa agtcagatga gtgagagtgg atttgcgtca atgtttagtg
     2221 acgtaaattc acgataagcg aatattttgc atgaagcaaa ataaagcgta aaaggagttg
     2281 agagcgtgac acgctttcgg ctcctttttt cgttgtcact tgtgacggcg aaaaccctcg
     2341 gagagcgttt ggaattgtga cagtcatgtc acaattagga aaacgttact ctttgacaaa
     2401 gagtaacaga aaggtttaca ctctttttat tagcgacagc gcgaaggagg ggtttaactt
     2461 ggggtttagt atttcgttca aaaagggaac aaagaataca agcatttctc ataataatcg
     2521 tgagttaact gatagccaaa aaatcaatga ctggcataag catattgatt tcacaaaatc
     2581 ggatgaaaat atctatttgg aacaaataaa tattcgtgaa aaatatgaag aattattcgg
     2641 tgaagccgta gaaaaatata atgcaaagca gaaaagagcc gatagaaaaa ttgaggacta
     2701 tttagcaaag gttcgcaagg ataaaaaaat ggaaccacag cgagaattta tcgtgcaaat
     2761 tggtactctt gatgattttc gtactactcg tgatgatggt tcttctactg gcatatcgga
     2821 acaacaagca gaacaaaatc gagtgattgc caacaaaatt ttagttgagt atttcaaaga
     2881 atttaaagaa cggaatccta gtttatccgt ctacaatgct gttattcata atgacgaagt
     2941 aagtccgcac ctgcatttga atattgttcc tgttgctgaa gggtataaac ggggtgttca
     3001 aaagcaacca agttttaaca aagccttgca acagcagggt ttacgagcag ataaagagaa
     3061 tggtcgagtg atttggaata attttaggaa tcaggaagtt gagtcaattg aacgtttgat
     3121 ggcagatttt ggttgggagc gtgagttagt cggtactaac aaaatcaaag atattcatga
     3181 atacaaagaa atcatgagcg aaatttccga attgcgtcaa acggccgtaa aagagcgtga
     3241 gagcgtttct gatgagttga ggtatatttg taggcaaaga gaagaaaacg agcgtgagaa
     3301 ggctctggtg gcttctgaga gagcgaagat tgaagaagag aagaaaaata tgctgaatgt
     3361 aaaaaaagag atggcggtca ttttccaaaa agatatggtt cctttagaaa gtttcaagag
     3421 gcttcctgat ggttcgtatc atttatctgg gaatgatttt gttgatttgt atcaacgagc
     3481 tacgagagca acaaatgcca agagaaatgc tgataacatg agtgagcaat atttacagat
     3541 gcttgagcaa aatacagaat taaatgagta tgtagctgca ttggaagaag agcgtcattt
     3601 gtctggtaga aaacaattag cagatttaca agtggaaaat aaaaagctga aagaagaaaa
     3661 tcgctcttta cgccagcgtt tagagcgatt aaaaaacgca tttcaaaaat cgatcactcg
     3721 tttgtctatc cgttttgggc ttgcagaaaa ggatatgggg ctttctgagg aattagaagt
     3781 attagagcag gagaaaacct tattttatcg tcaaaacgtc tcacagcata aattagagcg
     3841 ttctgaagat gagatcgagt ggtagttacg atgtgcagtc aacggtaccg gaggcggttt
     3901 gtgccgagga taaggagttg acggctaaac cactagccta ttaagctgac atttgctaaa
     3961 aaatggcaag tccatttttt ggccaactta gcgttagcga agtttggggg cgcccttttt
     4021 aaagggtgcg gttttatgtt tgcatgacta agaatgagtg ggaaaattta acagccctat
     4081 ctaacaggcg gttaaatgta caaaatatgt acaccccctt aaaaatgcag tggtcgattg
     4141 atcgaatttt atgtctttgg gttttggggt tttaaaacga aaaaaagggg gcgattttcg
     4201 ccctcttttt tgatgttttt tcttatcttg atactatagg caactatttt cggcagaaaa
     4261 tcggggctat agtatgggtc tatcccttgt ggctctaagg aagaac
//
LOCUS       DACBZK010000139         4287 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.145, whole genome shotgun sequence.
ACCESSION   DACBZK010000139 DACBZK010000000
VERSION     DACBZK010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.145"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(127..1293)
                     /locus_tag="IVD66_002742"
     CDS             complement(127..1293)
                     /locus_tag="IVD66_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HAP6146907.1"
                     /translation="MSHIQELVEKLINKMSAIFLLLLVSILYLIWTVGLNPPTILFIY
                     DNAAQLVTFFVGCLFLLNLYKVKRNDLFFIAAGILFYLFFSFFRSYRGDTFYGDLIVP
                     TIIAIILIVKWTEFTVFDRSLYLVVFYVFLLVTVYRVFTEIPVPEGQSIWNPSNKLSD
                     IWINTNTIGSSLMTLALLITGFASSFGKWYMRLLSLPALILAGATIWVCQSKAALYAL
                     VIFVILEILPKKIFRNTHLSFWMYAAVSVLALPISYFAAMSDKVHLFTGREEIWRKFY
                     ETLGEKTGQIFVGMKPFFFHRGNQILGNHNTYHALVNHYGLIGFALSMILLLSFLWLL
                     VRKCELTNGQLTFLWAFLAIMCQSFMEETLATISWVPIVFLMLAMATHQYKTTR"
     gene            complement(1299..1988)
                     /locus_tag="IVD66_002743"
     CDS             complement(1299..1988)
                     /locus_tag="IVD66_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HAP6146908.1"
                     /translation="MNKNNKTLFNPYVGVIIVFLLFSYFAYQGYQKDKIAEKVDDVTK
                     TIHIQEQAKTYQDNLTSLTDISKRQLITNQKQALEKDLKGEIAGKLVFSSTGFILPVF
                     QGANSDTLSLGVASTYYPDAEMGNGNYILAGYNVDTPSVLLSDMIDLSEGEEIDLIDA
                     HYKYQYEVSKRGKIYDYSQVVQSKENNSFLSLPKAGKKPLLTLLDFEANNMKKCDVIQ
                     CELVNVEKINK"
     gene            complement(2115..2354)
                     /locus_tag="IVD66_002744"
     CDS             complement(2115..2354)
                     /locus_tag="IVD66_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146909.1"
                     /translation="MNCKESVNWKKVSKEMEEKLLKMMKQKHLKRLSVMQYINDMQIT
                     GKEKACLLGSMKNFEQLRRTYVKTSSNCQLLLEVS"
     gene            complement(2421..2660)
                     /locus_tag="IVD66_002745"
     CDS             complement(2421..2660)
                     /locus_tag="IVD66_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146910.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            complement(2774..3115)
                     /locus_tag="IVD66_002746"
     CDS             complement(2774..3115)
                     /locus_tag="IVD66_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAP6146911.1"
                     /translation="MKNYDPNIRWGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEEDLYDQKLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            complement(3735..4067)
                     /locus_tag="IVD66_002747"
     CDS             complement(3735..4067)
                     /locus_tag="IVD66_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HAP6146912.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQNKTVVQCKKYI
                     IQKDKVSEEMIYYVGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
BASE COUNT         1334 a          871 c          594 g         1488 t
ORIGIN      
        1 gacgattaaa gcgactccta aaaaaccaaa taaccatttt ttcatccatc tgcctccttt
       61 cagacaaaac aaaaaacact ttttcacaac gaaaaagtgt tttctcttat tactattcta
      121 tttcatttat ctggtggttt tatattggtg tgtagccatt gctaacatta agaacacaat
      181 tggtacccaa ctgattgtag ctaatgtttc ttccatgaaa gattgacaca tgatcgctaa
      241 aaaagcccac aagaatgtta gttgtccatt tgtcagctca cattttctta cgagcaacca
      301 taagaaacta agcaaaagaa tcatcgatag agcaaaacca atcaatccat agtgattgac
      361 gagtgcgtga tacgtattat ggttacctag aatctgattt cctctatgga aaaagaaagg
      421 tttcatccct acaaatattt gtcctgtttt ttcgcctaat gtttcataga atttgcgcca
      481 aatttcttct cgtcctgtaa ataaatgaac tttgtctgac attgcagcaa aataagaaat
      541 cggtaaagct agaaccgaaa ctgctgcata catccaaaag gacaagtgtg tgtttcgaaa
      601 gatcttctta ggtaaaattt ctaggataac gaagataaca agcgcgtata atgctgcttt
      661 cgattggcaa acccaaatcg ttgccccagc aagaatcaac gctggtaatg atagcaatcg
      721 catgtaccat tttccaaatg aactagcaaa tcctgtgata agaagggcta atgtcattaa
      781 agaactacct atcgtatttg tattgatcca aatatctgat aatttgttcg atggattcca
      841 aatactttgt ccttctggta ctggtatctc ggtaaatact cgataaaccg ttacgagtaa
      901 aaagacatag aatactacaa gatacaagct acgatcaaat acagtaaatt ccgtccattt
      961 tacaatcaaa ataatggcaa taattgtcgg aacgatcaga tcaccataga aagtatctcc
     1021 tcggtagctt ctaaaaaaag aaaagaaaag gtaaaaaaga atgcctgctg caatgaagaa
     1081 tagatcgttt ctctttacct tgtacagatt caaaagaaac aaacagccta caaaaaacgt
     1141 cactaactgt gcagcattat cataaataaa taatatcgta ggaggattta accccaccgt
     1201 ccatattaaa taaagaatgg ataccaacag taacagaaaa atggcactca ttttattgat
     1261 caatttttct acaagttctt gaatgtgact cacttccctt atttattgat tttttctaca
     1321 ttgactaatt cgcactggat cacatcgcac tttttcatat tatttgcttc aaagtctaac
     1381 agtgtgagta gtggtttttt acctgctttt ggcaaggata aaaaggaatt gttttcctta
     1441 gattgaacta cctggctgta atcataaatt tttcctcttt tggagacttc atactgatac
     1501 ttgtaatgag catcgattag atcaatttct tctccttcgg ataaatcaat catatcggat
     1561 aataaaacgc ttggtgtatc tacgttataa ccagcaagaa tataatttcc atttcccatt
     1621 tcagcatctg gataataagt agaagctact cctaaactaa gcgtgtcgct attcgctcct
     1681 tgaaaaacag ggagaataaa tcctgtagaa gaaaaaacaa gttttccagc aatttcacct
     1741 ttgagatcct tttctaatgc ctgtttttga ttagtaatca gttgtctctt agaaatatcc
     1801 gttaaactgg ttaaattatc ttgataggtt ttagcctgtt cctgaatatg gattgttttt
     1861 gttacatcat ctactttttc agcgattttg tccttttgat aaccttgata agcaaaataa
     1921 ctaaaaagga gaaaaacaat gattacgccc acgtaaggat taaataaagt tttattgttt
     1981 ttattcatct atctaccttc tatatattaa ttaatttacc tacaactaac caagataaac
     2041 cacgttaaat tttactattc tttttattca ataacaatgc cacatcataa ttgatcattt
     2101 tcatatcata atcgtcaaga aacttctaat aatagttggc aattagaact tgttttcaca
     2161 taagttcgtc tcaactgttc aaaatttttc attgatccca atagacaggc tttctccttt
     2221 cctgttatct gcatatcatt gatatattgc atgacagata atcttttaag gtgtttttgt
     2281 ttcatcattt ttagcaactt ttcttccatt tcttttgaca cttttttcca atttacgctt
     2341 tctttacaat tcatgagttt tcctaccttc cctgtttttt gcaaaaataa aaaagcctat
     2401 gatcacatac gctctacact tcagtcttgg gttatctttt tctttcgttt aattactggc
     2461 cgtgctggtt tcaaatcctt gattccatta tgggttctcc aataatcgaa ttcttttcgt
     2521 aatctttctt tttccatatc tgttccttta gatagggctt tgaatacatc tttaggtgaa
     2581 taaccacgag ctaacagctg tacatacctt ccttttgtca aagtatccat atccatcgcc
     2641 tctaaaactg gtcgcgccat ctaattttcc tcctaaataa attccttact caatgcctaa
     2701 ggtaatacta cctttttatt aatcgtcgtg actccttcta agcctttatc tgtaaaattt
     2761 attcctccag tttttattct tctttatccg ctacaaattc aatgatttca acgctgacaa
     2821 tataatcact caaatatgac caagtatctt caacagataa ttcgtctcca ttatcattca
     2881 taagcgtcat tttaaaccat tcattacctt catcatcttc aggtagcaag ccgaatccaa
     2941 ttggattatc agtcaatttt tgatcgtata aatcttcctc gtctaatgct aaaacatcta
     3001 atcctttaca atttccgcct cttctaaacg tcacaaatcc tttgtaatcc caacgttgga
     3061 aagaaacctt aatagtatgt gtgccccatc gtatattcgg atcataattt ttcatttgtc
     3121 attcctccat tacgtaaatt tcattttctc tatgttttat atcaattttt tcactttatt
     3181 caggactcgt tcatatttta tcgtttttcg tttacttaaa aatacataaa aaatatcgac
     3241 tcgtttatgg cgtccgaaac gagaaaccct agtagaacat cggtaaatgc tcgattgatc
     3301 caataatcaa cgtcctcgca agtatctaca tgtactgcag cacacgacac aatttcttgt
     3361 gcgtcctccc cattacgaga agacctactc cttattccat gagtttgcgt caaagcctag
     3421 atcccttagt agctgctcat gattaatcta ggcgctattc taacttgtct aacttctaaa
     3481 ttccctcttg tttactctgt gcatattatt tacacaaatt catttcacca ctatccaaac
     3541 aagggcattt actcgattga ccaatttttt acgttaccaa tcgtaaaaac ctaccccatc
     3601 actccccgaa gggaattgtt gatagatcaa gtctactcct tatttttcta gtgattctaa
     3661 gttcttttag aagtctcgac aatattttca agcaagcgaa aaacgataaa atacaagtta
     3721 taagaatgat caattcagct gatcaaacgc cccatccctt ttgcggtaca acgtaagact
     3781 ccattttttc ttcgacctat caatacaccg ttttggtcat aaacatgttt gattgttgga
     3841 tatagctctt ttaaagggat aggatctttt aaaattattt gcttttgttt cccaacgtaa
     3901 taaatcattt cctctgagac tttgtctttt tggattatat atttcttaca ctgcacaacg
     3961 gttttatttt ggccagttga tagtttcttc gtgatcttct ctgtagcggt acaccgttta
     4021 ccgtagtgac aaatatcttc gagactcaaa attcctgtat atgacataaa ataatccacc
     4081 cacttacttt aaatattttt aacaagtttt tcttgttatt tttcaaaaat agagaattga
     4141 ttttcgttca tgacaaacaa aaaagaggga acgcatccaa acatgcgttc cctctaattt
     4201 cagcgttcat catacggcaa agagccacac ggacattttt ataacattat gcttaggcat
     4261 agattcatcg taatatcacg tattttt
//
LOCUS       DACBZK010000140         4282 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.146, whole genome shotgun sequence.
ACCESSION   DACBZK010000140 DACBZK010000000
VERSION     DACBZK010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.146"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(37..1257)
                     /locus_tag="IVD66_002748"
     CDS             complement(37..1257)
                     /locus_tag="IVD66_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP6146913.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1277..1882)
                     /locus_tag="IVD66_002749"
     CDS             complement(1277..1882)
                     /locus_tag="IVD66_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005234653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP6146914.1"
                     /translation="MKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELPLF
                     NKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVDKP
                     VMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLIDEE
                     QVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1931..2863)
                     /locus_tag="IVD66_002750"
     CDS             complement(1931..2863)
                     /locus_tag="IVD66_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAP6146915.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLEELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
     gene            complement(3284..4144)
                     /locus_tag="IVD66_002751"
     CDS             complement(3284..4144)
                     /locus_tag="IVD66_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6146916.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT         1220 a          861 c          699 g         1502 t
ORIGIN      
        1 tttattcttt atttaaaact ttgcaacaga acctttttat tttacagaag cactcgaaac
       61 tgcatctact gcagtttcat cgtgtgtgct ggcgctggtt actgcatctg tttttccacc
      121 atgaacagat gcacttgaaa ccgcatcttc atttccaaca agttgttgac ccgtttgttg
      181 taaataccac tcaatgattg gtttgaaatc aagaatgtat tcattgattc cagcatactc
      241 tccattttca tcatgcattg cttggtaatt atgcacaata tatttttctg gcacttgttt
      301 tggtacatga acacgtaccg catctgttgc tccgcttcgc agttgttgaa ttacccactc
      361 tacattttta tacgattttt ctgggtgaca gttggctaat ggattcccta cctgaccggg
      421 cacacgagca gctaacatct ctttcgcttc ttggcgcaaa ttataatata aaaattggtt
      481 attattatct gcaaaagtta attccatcgg catcgaatct aaaaagtaat tgatttgatc
      541 cactgtcaat aacccacgat ttaatttgac gtaagtattt ccagaaacgg caccgactgc
      601 ttcagaagct ttttccaacc aatgatcatc tgacatatca acatcgggta ttgtcgtagc
      661 aattgttcct gtcgcatgca aatcttctgg tggaagcttt ttaggccctg ctaaggtaga
      721 cacgacttta atgaatttta caaaacttgc taatgtactg cctaaaaagt caacagttcg
      781 tggatcaatc aagcgatctt cttggtcaaa tgcttctttt gcttttccca ataaaaattc
      841 atttccgggc atcactaatg cattcacgcc tggtgcgtcc aaaatttggc gcaagtgtaa
      901 ttgcgcgcgt gaagttcctt gatcgtagta agaagcaccc acaaccatta caggtttatt
      961 ttcaagtgga tggattttaa atgatagcca ttcaagtgca cttttcaatc ctgctggaac
     1021 cgtatgattg tgttctggcg tagcaataat taccccatca gccattaaga ttttgcgatt
     1081 tagctgttga atagcaggac tatttgtttg atcatcatct tgattgaaca gaggtaaatc
     1141 tttgatttca atgatttcta aattaaatag ttcatgatat tgtttttgga taaatgttaa
     1201 taatttacgg ttatatgaaa gttcagctgc tgatccgacg atacctatta atttcatctt
     1261 tgtttgctcc cctcgattaa atcgtttccc atgaaaagct ttcggcttca cgtttatttg
     1321 cttggtgcgc atgttgcaat tgactagtga ttgtgacaaa gagtaagaaa tctttgaata
     1381 gttcacgtaa ttttgcgact tgttcttcat caatgagtcg tccttgctca tcaaaggctt
     1441 ggagtgaatg acccaataaa aattctgagc ttggcataat tcgtgccttt aactctggtg
     1501 aatccaatat ttggcgcaaa tgtgcttgtg cgcgtgaaga acctaacgtg ccataagacg
     1561 ctccggtaat catcactggt ttatccacaa acggaaaaat accatatgaa agccaattta
     1621 atgcgttaat caatgaagca ggaaccgcat ggtcatactc tggtgtgctg atgattacgc
     1681 catctgcttg ttcaattttt ccagcaattt ctttaacaac atttggtagt tctgtgtttt
     1741 caggtttgtt aaatagtggc agctccttga tttcgacaat ttcgatttct gcctcattta
     1801 caaaataatt tttcataaac tgtaataatt cacggtttgt tgaccgcgtt gaatttgttc
     1861 ctactaatcc aataaatttc atcttcattc tctttccttt ctaacatcga tttctgactg
     1921 ttcgcacgta ctaaattttt tcaaatcctt ttgtatacaa gaattgattc tcttttgtta
     1981 caactgctcc ctcgataccc ggctgttctt caagcgcttt caacacttct aaagaagatg
     2041 ctccaaataa acgtgtagtc cagatttctc catctacaga agaatcagac aaaatcgtca
     2101 ggcttgctac gtcattttta actggaaagc cagttttcgg atcaatgatg tgatgataca
     2161 ctgacgaacc attttgtaga taacgttcgt agattccaga ggtaactaaa gattggttgt
     2221 ttagtttaac caccgcaagc gactcttcac gtgaaccttt aggatttcgc aaaccaatac
     2281 gccaagcacc atccgaacgt cttggtgatt caccaaaaac aacgatattt cctcctaagt
     2341 taactaaagc aaacgctgca tttcgctctc ggcaatgtgt aattaattta tctgcaatgt
     2401 aaccttttgc taacgccccc aagtcaatca tcattcctgg tttggttaaa aaaacggttt
     2461 tcattttttc atctaattga atttggtgtg gatccgttag cagaagtaac tcagttatct
     2521 ctgcttttgt tggaaccaat gcatcttcaa atccaatgtg ccatttttgt acaaccggac
     2581 caatagcaat attcagataa ctatttcttg cacaactatg tgcttttcct aatttgatga
     2641 gctcaaaaag ttcaggatgt acaatcacag cttgtcgtcc agcagcttga ttgatggcca
     2701 ttaattcaga agttgcatca tgtgcgctga agcgatgttc ataaacgtgc aaccattcgc
     2761 ctaactcttc tagtaatcga ctaggctctt catgcccaac ttgtaatgta attgttgtcc
     2821 ccatcatttg ccagattttc gtttcttcga tcacctgatt cattttgtac cttctttact
     2881 tgaactacgg attacatgag taattagttt ttatttttgt tactgttttc acaaccagat
     2941 gatacgcctg ctagatttat ttgtcaaccg attttatata tttttttata taataaggta
     3001 attttaatat aaaattttat attgtaaaaa aacaaataag ggaaacaaac aacacatttt
     3061 tgtgtgttgc ttatttccct ctaactatcg ttttctattt gatggttaac ctacttaaaa
     3121 taaatactgc aacgacaaac ggagatcaag catgctttgt aacgtatttt acgataatta
     3181 cgactttatt ttattactct atcttgctgc catacccgtc tatccctaat catctttggt
     3241 gaattttttc aaagttagca taacaaaaat aagtattttt tccttagtta atcaatagta
     3301 tcattttttt catatgattt aattcatcaa ttaatttttt gtttttatta attttagcaa
     3361 aagctagtgc atcttgaatc aattcgagca cttctgcctt cgacttattt ttagcctgtg
     3421 cgttcttcgc taattgggca gcagctcgtg ctaagtaata agtcaaatgg ttatccgaac
     3481 aaatatcgat tgcgtaattt agtagtgcat cacttgtttc caaatcaccg tcttgcgcaa
     3541 aaaaaacacc acaatgaaag acgatattta acacccgcca gatatcttct gttgtacgaa
     3601 tcggatacgt ataaattttt tcaaacactc gattgaaata aacttctgct ttttccaact
     3661 ctttttctct agcatagacc attccaatac ctgtatatgc caataaacga aacaacgtgt
     3721 tggctgtttc tgccatcaac aactgatcaa aatggaacaa cacatccgta attggtgcat
     3781 tcgtaaaaat catttcaaat ccttttagat agtagtaacg tgcaatcagc tcagactcgt
     3841 caattacctt gggatcaatg gctgctaaaa tctgtgtcaa ttgttcatat tcactcgtaa
     3901 tcagtgaaaa ctctgctttt tctagctgtt catcaagttg tgtattgatc acgttcatcg
     3961 aagaaaaaag ttcaactaac ggaagattga ttcgattaca taatttgatt aaaattttta
     4021 acgaagggac ttgaccattg ttctcaaatt tacttaatgt tgcttgtgta caaattcctt
     4081 cagacacttc tttttgagat aagttggcag cctttcttgc cgtaataaat ttttcaatgt
     4141 tcattatttt ctctccaatc aaacctcaca cgaaaatcat ttctgtctcg attttagcat
     4201 gttttctttg ggaatgcttt aggttctgtt gcaaagtttt aaataaagaa taaagtccct
     4261 tacggtatct atgatttaag ct
//
LOCUS       DACBZK010000141         4166 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.147, whole genome shotgun sequence.
ACCESSION   DACBZK010000141 DACBZK010000000
VERSION     DACBZK010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4166
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.147"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(130..2040)
                     /gene="ltrA"
                     /locus_tag="IVD66_002752"
     CDS             complement(130..2040)
                     /gene="ltrA"
                     /locus_tag="IVD66_002752"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP6146917.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(2786..2905)
                     /locus_tag="IVD66_002753"
     CDS             complement(2786..2905)
                     /locus_tag="IVD66_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAP6146918.1"
                     /translation="MGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKGK"
     gene            complement(2920..4104)
                     /locus_tag="IVD66_002754"
     CDS             complement(2920..4104)
                     /locus_tag="IVD66_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP6146919.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
BASE COUNT         1090 a          897 c          655 g         1524 t
ORIGIN      
        1 tatatggata ggtaagttcc tgatattata aatatctcaa acttttcccc ccattcacac
       61 ggagcgtgcg actttcaccg cactccgcgt tccatcgtgt ttatattgaa aagtatttat
      121 gtagtagacc tatatcaagt ttaattcttg attgccagct aatactctat atttatttag
      181 tcttatgagc tggactttat ttagcttcaa tagagctata tatttttgta ttgtttcttc
      241 tgttttagcg tgtattagac ggtgtaccgc ctcttttacc aaaataagat ttttataatc
      301 gtcatttcca ccagctccag ttggtacaat atgatgacaa tgtatttcat tagcttgttg
      361 aaattcttcc agagttatag cacattttcc atgttgagca gaaaatagcg aaattcgatt
      421 gtctgcgtat tctattgtgc gattttccaa agataatttc attaactggt acatcagtaa
      481 tttatcaaca cttagattgg tgtggataaa ttttcttccc tctagagtgt agcaattcgc
      541 taaatacacc tttgccattg gttttctgtg ttggatatat ccaacaggga aaataggttc
      601 gccctcgcca gcaacatacc gaagcatttt agatttacca tatcttgttg cctcctttgt
      661 cgtaagttgt ctgcctgttt ttctcaatct gccccttttg tttgtaccta atctgttagt
      721 gaagatagcc attacagctc tattcagttt catacaatcc agatttacat tcgttgcaat
      781 ctgataataa ttttgcatac ctaataccat tgaattataa agtcttgttt cttctaattc
      841 cgttttccct tttgagggag aagcaatttt ctttgcctgt gataccagct tgtctttttg
      901 gtttttgaat tgtttatcac ttatatgtga tttaacaact aacttctttc ttctcggtat
      961 cattttaatc ttgaaaccaa gaaagtcgga gtatcttttt ctaacattta caattcttgt
     1021 tttttcttgt gatacttcca attttaatcg ttgttcaatc cattgagtga ttgctatttt
     1081 ggctttttca gcactttcct tgtagcggca gaaaactcta aaatcatctg cataacgaac
     1141 catatacatt tcctttaact ttgttttctt catttctttg taagcgttgc ttttacatgg
     1201 gctaccgctt ttattgatat gaaccacata gttttttgta acaggatttt cctgccattg
     1261 gctttctacc caatggtcta actcattaag aacaatgttt gctagtagtg gggatattat
     1321 tcccccttgc ggagttcctt tctctggata tgttattgta ccgttagtca ttttgattgg
     1381 agcttttaat atccttttta aaatgaatat caagtgcttg tcccgtattc ccatagccca
     1441 tatctgtttt atcagcttgg aatggttcac gttgtcaaag aaacccttaa tatcaaattc
     1501 aatcacataa tgtagctggc tgatttgtag gcggttatag gttgctttta ttgcattttc
     1561 aactgaccta ttaggtctaa aaccatagct gttttcacta aatttagctt cgcagattgg
     1621 ttctaatact tgttttatac attgttgtat aagcctgtcc cacatacaag gaatacctag
     1681 aggtctggtt ttaccatttg gttttggtat ttcttttcgc ctcactggct taggtcgata
     1741 cccatgtgga ctgcctgcaa caatgtatct tacttttttg acaactgttt ctgctggcaa
     1801 tttgccaata tctttaatta ttgtaccgtc tgttcctgct gttttactgc ctgcatttgc
     1861 tttgatattt cgatatgcca gtaatatatt ttctctcgat aggataatat ccataagatg
     1921 agtgaaaata tctccattct tacttttggc atataaatca tcaaaggtgt tttgcatttc
     1981 gtaatattca gcgtgtctta aatcttctac acacaatgtt tcatttttat ttttaggcat
     2041 aaggcttcac tcctttactt gaaattgagt gagctttttt atcttactcg taatccttat
     2101 tgaaacaaca taatactttt ctaatatata cacgacttga gggcattcct ccattctcat
     2161 tacaagaatt tcttaggttc gccctctgct tttcagcatt agttcaactg cttattgttc
     2221 ttcgtcagtt tattctcttg atgagaaccc aatacctttc ctcgttccga taatcttatc
     2281 tatacatata tatccttagg tcactagcta taagcctgct ggcttgatac cgcctgtaac
     2341 gttatatggc atttcataac ctatattctt actttgccac accagctacg atttctcgta
     2401 cctttgcatt tctacaaagt tcaaatttag acccgtacat tcgctgtttc gtcagttcct
     2461 tatagaacat tctaaccata gatattttat agacccccga cctgttggat acgctaccca
     2521 cctctggata gttttcgata gaagatatat gttcatcaac tattacggta tctttcagcc
     2581 gtctttaccg agcttcaaac attctgagtt tcctcataca atgcttgtcg gaggctcagg
     2641 gcaggcgttt cagagcgtta cttcatcatt ccacctgtca gattatcagt tctcctaata
     2701 accaaacttt ttcgttcttt tattagtgcc ttagcttttc actaaggaac gagtcgcaca
     2761 taaattttgt ccgaaattca tcttgtcact ttcctttctt ttccattgct cgatccgctg
     2821 ctgcacttgc attcatcaag cacatcacag taacaccaag catactgcca ccaaatacca
     2881 aaaaaatatc ttttacaatt cccatgacga ttcctctttt catataatca aattttcaat
     2941 tgccatactt tgttgctcca aaatcttttt atgtcggtct gataagcgtg cattctgtac
     3001 catatcctgg atataggttg tccgattcaa tcgatccaac tccttagcca ttttccacgt
     3061 aggggcgact tgtcggccta gccaattcaa ggttcgttca atggtatacg gttttggctc
     3121 ggaagttaat tgaatctctt tccgattccg tccaataaaa cgcccccatt gttcattcaa
     3181 gggccagttg gttcgccttt taccttctac tttatccgca aatcgcaagt aacgattgat
     3241 aatggaaaac gtggtgctct caatgctacg accttttaac aaatcttgaa tcgcatgaaa
     3301 agcacggtca tttttcagtc gaatctcaaa acgatttttc gtctcagttt ggtctaatgg
     3361 aatccctaac ttgatatatt gttcatagtc tttttcatac aaacagaaat aaacctcact
     3421 cttgagactg ccgatatata aggtattgcc catgccgtcc ttttcatcag cctttaaaag
     3481 ttccccggaa cgataacttt taaaggtacg aaacaaggag atacattctt ccttctgaca
     3541 ttttttcgtt agctcaggta tatccaatag ccccactcga tcattgattg ccaagtccaa
     3601 gcgtttcatc acgccaccgg cctttagaca atcctcgaaa aagtcgtacc agctacgctt
     3661 ttgagcgagt aaaaaagttt caaattgtcg gcaacctcgc ccctttaatt ctaaaagcac
     3721 acctttatct tcttcatgag acaacatcac cacaatatca cccatgacat actgttcttg
     3781 ataggagtaa aaggcataat cttcatggag catatactca aatttcaaat ggagaatttc
     3841 ttgaataatt tttcgtgcat ccgttgtggg aaagcgaatc cttacatagt caaacagtaa
     3901 cgtcaaaggc aaatcgggat taaagctttc cagttggtca aaaattttcc tcatggtttt
     3961 tatagatgcg gttacgccac cattttctat ctgatttaag tacggccgac taagtccaca
     4021 agccgtagcc aatttatttt gtgaaacgcc gtattcgttg cgtcggtctt ttaatagccg
     4081 ataatctaaa ttccgttgtg ccaagttctc acctccaaat tcaaggtgtt aactttttca
     4141 aatgagttaa cacctataca aattac
//
LOCUS       DACBZK010000142         4112 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.148, whole genome shotgun sequence.
ACCESSION   DACBZK010000142 DACBZK010000000
VERSION     DACBZK010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.148"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(39..281)
                     /locus_tag="IVD66_002755"
     CDS             complement(39..281)
                     /locus_tag="IVD66_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP6146920.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(313..870)
                     /locus_tag="IVD66_002756"
     CDS             complement(313..870)
                     /locus_tag="IVD66_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP6146921.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(883..1071)
                     /locus_tag="IVD66_002757"
     CDS             complement(883..1071)
                     /locus_tag="IVD66_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAP6146922.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(1084..1650)
                     /gene="amaP"
                     /locus_tag="IVD66_002758"
     CDS             complement(1084..1650)
                     /gene="amaP"
                     /locus_tag="IVD66_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAP6146923.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            2880..3353
                     /locus_tag="IVD66_002759"
     CDS             2880..3353
                     /locus_tag="IVD66_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HAP6146924.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            3362..3589
                     /locus_tag="IVD66_002760"
     CDS             3362..3589
                     /locus_tag="IVD66_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6146925.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT         1234 a          740 c          617 g         1521 t
ORIGIN      
        1 ttgttcttca tttcaacata agtttttctt caatttgctt ataatttacg tgcaaagaat
       61 gaaacgacta atactaaaat gattgcaccg atcaatgatg gaatgatagc cattcctgca
      121 attgttggtc cccaagttcc tagtaaagct tgtccaattg ctgaacctac taaaccagca
      181 atgatgtttg cgatgatccc cattgatgat cctttattcg tgattgctcc tgcaattgct
      241 ccaatgatac cgccgacgat taatgcccaa ataaatccca ttttaaattc ctcctaactg
      301 acttcttact tcttattgta cacgtggttc gttattttct ttgacttttt gtgcaccttt
      361 gcctacagca gattttgctt tatctgtttg gcgtgaagca aattgtcctg tggattttgc
      421 tgcttctgtt actttgtctt gtactgtttc ttgatctttt tggtattctt cttgtgtttt
      481 gatgtctgca acattcacat tcacttcgat aacatctaaa tgtgtcatat tgtttacttc
      541 agtactgatc aattctttga tttggttgta aatatcttcg atgtctttac cgtattctac
      601 gatcacatct agatccacag ctacttgttt cttacctact tctgtattga tacctgctgt
      661 tacgttatct gtgttgacta atttttcagc catatttgag aaaaatccgc catctaatgt
      721 caatagacca tctacatctt tcaatgcata accgatgatt ttttggatga ctttgtcttc
      781 ataagtcaat tcaccattca tcatgcggtt ttctcctttt tcatttgcca aaactgatcc
      841 atttgttgta ttcatgtttt tgttttccat ctttgtttcc tcctatgatt taaaaaattg
      901 atcaactatt cctgactgtt tcaaataaaa accgattcct gcgccaattg ctgtcatgat
      961 tatgatcaac aatgtcttga aaaatccaat cgttaaccat aaaacagcta gcagtagtcc
     1021 aagaccccca aagataatag ggagcttgta tgctgaaaat agttctttca ttatttggcc
     1081 ctcctattcc actcgagagt gcttgtagtc tcttgtatct tcttgttctt cataaccgct
     1141 gtatgtgact gccactttga ccgtttcttt tgttccgagt actttagtta cttcttcttc
     1201 gatatcttgc atcaatacac ctgttttccc tactaatgaa gaagttcgtt tcaagtctcc
     1261 gttgacatgg atatggattc gatttttcgt tgaacgtatc cgtactttag gtgaatgaat
     1321 gaactcttct tcgtgtaaat gggaacgtac caacccttcg atcgcttttt tgtcgattgt
     1381 tagtttgcca tcttcccgtt tcataacgaa agttcctctt gactttggat agaaaagaac
     1441 gactagcaag atgataatag caagaacggc aaatactaca gctgcccaga aaatatattg
     1501 ttgcatgtag taattcgtta aagtaaagaa gcgaaatcgt tccaattgtt caggcataat
     1561 atacggcgca ttgatcaacg caatcgctag aaatactgaa agtagcagta aactcatgat
     1621 aacaccgatt atttttaacc ccttattcat tttccacctc ctataaactt atttttaccc
     1681 tgtaaataac tctaccgaca atcacagtat agatagcgaa cagttagcat agcatcagta
     1741 aataaagcgc taccaaacat tgctggatca taacggcgtt ttattgccag tctgatactg
     1801 aaataacaat tgcttactta ttctctattt acttttgatt gctggctata cttaaaggat
     1861 attattcaag attaaaaatt gcaaagatta tgctcagtta ttattacaag attctattta
     1921 tttattaaat tttttcggag aattaaaaaa tacaataaat aactttagtt actttaatgc
     1981 gttcttactt tatttttata ttatcatttt tcttattcac ttctttggtt tatactattc
     2041 ttataaataa aaacgaggta tgtcctatga tgaaaagatt gtactattca ttgatcataa
     2101 cgattggcta tttgattgta tcaaatctag gaaatatggt atttggtatc agtaaagaat
     2161 tcagttggac tactacatta tgggaatctc tattcttttt catcttcgta tttttgttac
     2221 aaaattatcg aaaaaaataa acatgtgcca tctatctgtt ggcacatgtt ttaggattta
     2281 tggtactttt tattcggcaa tccattttat ttttctactt cttcttaata cctctaacac
     2341 ttttgattta taaactaatc caatgcatct acttgcgctt attaagctat ttcagctaga
     2401 tagtaccacc ccatgcgtca atgcttgatt ttccttttgt ataacattgt ataagcaata
     2461 aaggacaaat aagtggtgat tacaccaaac cattgaataa gaaaaattct gatacgtaaa
     2521 taaacatgaa cttgaaaaaa ttaatgaatc ggttagctac tacgtagttg tcttttttct
     2581 catacagttc tgttaactta cacttctctt cgctagataa taaaaaatcc tccaactgta
     2641 ttgtccaata taatcccagg catctaaact agcattatag aagagacaca catagaatct
     2701 aaaataactg gttttaaatg tttcttacaa tcaaaaaaag ctgttaaatg cactccacac
     2761 cttcatactc tatcattttt tataaacgat atatttttat tgtttttcga taaaaaatag
     2821 ttgttttaca ataattattc tgctatattt tagctatcaa agataaaaga gggataaaaa
     2881 tgaaatttaa aacattgcta ttaaaatttg tcgttttagg tataagtgcc gtatttattt
     2941 tgttcggcgt acttttttat actcagatcg ctacaagcga aaaaggattc aattttgatt
     3001 ggcagaccac attatttgtt tctgtcattt actttgccct tctcctaggg atcgttattg
     3061 cttatttctt attgaaacta ttgaaaaaaa tcgaagataa ccaagctttt tccactcaaa
     3121 gcttaaacat actaaaaaaa atcgaacgaa ccattttgtt tattggtttc gccttttttg
     3181 gcttacttcc taaatttatg aaagtagcgg atttagacga tgctccaggt ttgatgttgg
     3241 taggaatcgc tgtcgtattc attccttttg cagtatacac attaacaagc gtgctggaaa
     3301 aactgcttga acatgcgatt ttacttaaga cagatcatga tttgacagtg tgaggtgcga
     3361 catggcaatt atcgttaatt tagatgtagt attagctcaa aaaaaaatga gtgtgactga
     3421 attgagtgag aaagtgggca ttacgatggc aaacatctct attctaaaaa atggaaaagc
     3481 aaaagccatc cgtttttcca ctctcgaaaa aatctgccaa gttttggagt gtcaaccagg
     3541 tgatttgttg acctataaaa atgactcgaa tactatacca gaagaataaa ataaagtaga
     3601 acaaacagta aataaaaaat aatctgaatg atagatgtgt gagactttta gaagttattt
     3661 acgtctatta ttcagatttt ttatttcgat tgaataccgt tttatctata aataagatat
     3721 gtactgactc atacaaaggg ggccttttct tctccatgta ctatcacttt tcctgataca
     3781 actggtttcc tgttacgttg tagttggatc tgcttttagt ataatacttt attcattcca
     3841 ccagactgat agcagtttga gcagtctaaa taatcatgta gtattacagg ccattctgtt
     3901 tcataccttg aagtgcttaa aacttcagct aatggcccat tgtgttaact cttactccat
     3961 tcttttttag taagctccca tatatactgt aaagccttct atatattatg tcatgttgct
     4021 ttttaacatt tactatgtag ttttgataaa atgatttgaa taacagtgat ggacaattct
     4081 tttttatttt taacattatt ttgataataa tg
//
LOCUS       DACBZK010000143         4034 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.150, whole genome shotgun sequence.
ACCESSION   DACBZK010000143 DACBZK010000000
VERSION     DACBZK010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.150"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            79..234
                     /locus_tag="IVD66_002761"
                     /pseudo
     CDS             79..234
                     /locus_tag="IVD66_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
     gene            253..1530
                     /locus_tag="IVD66_002762"
     CDS             253..1530
                     /locus_tag="IVD66_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6146926.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1540..2196
                     /locus_tag="IVD66_002763"
     CDS             1540..2196
                     /locus_tag="IVD66_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6146927.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2196..3572
                     /locus_tag="IVD66_002764"
     CDS             2196..3572
                     /locus_tag="IVD66_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6146928.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3702..>4034
                     /locus_tag="IVD66_002765"
     CDS             3702..>4034
                     /locus_tag="IVD66_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP6146929.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1612 a          440 c          704 g         1278 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcagga taaggataag tgtattaatt gtggaaaatg taaaaaagtt
      121 tgccaaatga ataaagattc agttgagaat tgcaatcatc tggagtgtat cagatgtgga
      181 cgatgtaaaa atgcttgtcc agtggatgca attagttatg gagtaagaaa atagagagga
      241 gtagttagga aagtgataaa aaatgctata gcatatatta caagaaagaa aaatagaact
      301 ttaataattt ttatcatatt aactatagtt ctttcttgct tgtattcttg tttaacaata
      361 atgaaatcaa gcaatgaaat agaaaaggct ttatatgaaa gttctaattc ttcaatatca
      421 ataacaaaaa aagatggtaa atattttaat gttaatcaat ttaaagatat tgaaaaatta
      481 aaagaaattg aagaaaaaat aattcaatat gatggattag caaaactaaa agatgctaaa
      541 gtagttagcg gagaacaaag aataaataga gaagatttat ctgacgaatt taagaatgtt
      601 gtttcactcg aagctacaaa taatactaaa agaaatattt tatttagtag tggagtattt
      661 acaattaaag aaggtaaaaa tatagaagaa aatgataaga attcaattat tgttcatgaa
      721 gaatttgcta aacaaaacaa tctaaaatta ggtgatgaag ttgatcttga attactagat
      781 attgaaaaaa gtggaaaaat aaaaagtcat aaatttaaaa ttatagggat cttttctggt
      841 aaaaaacagg aaacatatac aggattatct tctgatttta gtgaaaatat ggtgtttgta
      901 gattattcaa caagccaaga gatattaaat aattcagaaa ataatgaaat tgcaaataaa
      961 attttaatgt attctggtag tgcagaatct acagacttag ccttaaacaa attgaaagag
     1021 cttaaaattg atgagtcaaa gtattttgtt gaaaaagatt ctaatgcgtt tgaagagtct
     1081 ttagagtcag tgagtggaat aaaatatata ataaaagtaa tgacttattc tattatgtta
     1141 ggtgggatgg ttgttctttc attaatcttg attctatggt taagggaaag aatttatgaa
     1201 ataggtatat tcttatctat tggaacatct aagatacaaa ttataatgca atttatattc
     1261 gagttaatat tcatatcgat accaagtata atatcttcct tatttttagg aaatgtatta
     1321 ctaaaagtaa ttgtagatgg attcattaac tcagaggatt caatgatttc cggtggaagt
     1381 ttaataaata atagtagttt tatgtcaaat ataacaacac ttggacaaag ttatttaata
     1441 ttaataagta ttattgtttt atcagttgta tttgcttctt cattaatgtt aatcaagaag
     1501 cctaaagaaa tcttatcaaa aataagttag gagaaaataa tggatatatt agaaataaag
     1561 aatgtagcat atagttatgc aaattctaaa gaaaaagttt tgtcaggagt aaatcaaaaa
     1621 tttgaacttg ggaagtttta tgcgatagta ggaaagtcag gaacaggaaa atctacactt
     1681 ctttccttac ttgctggact tgataaacct caaacaggaa aaatattgtt taagaatgaa
     1741 gatatacaaa ataaaggata tagtaatcat agaaaaaata atatatcttt agtatttcaa
     1801 aactataatt taatagatta tttatcacca attgaaaata ttagattagt aaataaatca
     1861 gcagatgaaa gtatcttgtt tgaactaggt ttagataaaa aacaaataaa aagaaatgtt
     1921 atgaaattat ctggtggaca gcaacaaaga gtagctattg ctagagcatt ggtatcagat
     1981 gctccaataa tactagctga tgagcctact ggtaatctag acagtgttac tgctggagaa
     2041 ataattaata tattaaagac attagctaaa gatagaaata aatgtgtaat agttgtaaca
     2101 catagtaagg aagtagcaga ttctgcggat atcattttag aactaagtgg taaaaagttg
     2161 aaaaaagtaa ataaaatgaa tttggaggtt gaataatgat aaaaaatgca tttgcttatg
     2221 taactagaaa aagtttaaaa tcattaatta tcatattagt tattttatct atgtcaactt
     2281 taagtctcat tagtttatct attaaagatg ctacggacag agcttcaaaa gaaacatttg
     2341 ctaatataac aaatagtttt tctatggaga taaatagaca agtaaatcca ggaacaccta
     2401 gaggtggggg aaatgtaaaa ggtgaagata ttaaaaagat atctcaaaca gatagtatag
     2461 actcctatgt aaaaagaata aacagtgttg cagatttagt tgattatgat attattgaaa
     2521 ctcaagagac tcttgcgaat caatcacctg aaagagcaaa gaattttaaa agaacagtta
     2581 tgttaactgg ggttaacgac tcaacaaaag aaacaaaatt tgtatcagaa gcatataaat
     2641 tagtagaagg aaagcattta gaaaatgaag ataaaaataa aatcttaatg cataaagatt
     2701 tagctgaaaa aaataacctt aaagttggag ataagataaa aataaaatct aatttatttg
     2761 atgctgataa tgagaaaggt gcagatgaaa cagtagaagt agaaattaaa ggtctattcg
     2821 atgggcataa tagcggtgta gtaagtgcag cacaagaact atacgaaaat acattaatca
     2881 ctgatattca tacagctgct aaagtttatg gtaataccga agatacagct gtataccaag
     2941 atgcaacatt ctttgtaaaa ggtgataaga atcttgatag tgtaataaaa gatcttggga
     3001 aattagatat aaattggaga gaatataatt tgattaaaag ttcatcaaat taccctgcat
     3061 tacaacaatc tatatcaggt atttactcaa tttcaaataa attatttttt ggctcattaa
     3121 tatttgcagg agttgtagtt tcattattat tattcttatg gatgaatgct agaaagaaag
     3181 aaatagcagt attactatca ttaggtatat caaaattaga aatttttggt caattcctaa
     3241 ttgagatggt atttatatca atccccgcat tcgttggttc ctatttctta gctcaatata
     3301 cagctgacaa gcttgggaat aatatattga ataaggttac tggtgatata gctaaacaaa
     3361 tagctaaaca atctgcatct agccaattag gtggtggggc agaagctgaa ggatttaaca
     3421 agacattatc aagtttagat atcaatgtat tacctaaatt catgatttat gtagttatat
     3481 ttatgagttt agtacttctt gtatcattga ttatttcttc attcaatata ttaagaagga
     3541 atccaaaaga attattaatt gacaataatt aaaattttcg gtgcttttta gcaccaaaaa
     3601 tgagagtgta atataaaccg tgtaagtaac catcaatcct aggcgggtgg ttgcttcacg
     3661 gtttttattt ttctaaaata agatcaagag gtgattacac gatggctaga aagaaaagaa
     3721 atcctgatgc tgagaagtta gctgaatcca ttttgaatac ttatcaaccc gaatctgtag
     3781 aggatatgca agatgtttta aaagatgtgt ttggtccctt atttgaaaaa atgcttcaag
     3841 gagaattgaa taaccattta gggtatgacg cccattctaa agagccaaag aaacatgaca
     3901 atcgacgaaa cggttatggc aataagacgc ttaaaacgag ctttggtaaa gtaaacattg
     3961 atgttcccag agaccgggag gcttcttttg aacctgagtt gattcctaat agaaaacgag
     4021 atgtctccga catc
//
LOCUS       DACBZK010000144         3891 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.151, whole genome shotgun sequence.
ACCESSION   DACBZK010000144 DACBZK010000000
VERSION     DACBZK010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3891
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.151"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            119..712
                     /locus_tag="IVD66_002766"
     CDS             119..712
                     /locus_tag="IVD66_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP6146930.1"
                     /translation="MKDKIQCIFDKHNGNLSLKDARSEGLSPMTLDRLAEKDKIEKVA
                     PGFYTLKEAFVDELYLAQSIYSRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     KLDEYAIQPHYTNKENFDLGITETESFYGNKILVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMDILKSPKEMTLYMLPLY"
     gene            728..1627
                     /locus_tag="IVD66_002767"
     CDS             728..1627
                     /locus_tag="IVD66_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAP6146931.1"
                     /translation="MTPTQFKAKTRNFATEKHLNPQIVQRYYMMEKLLERIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTADPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAYLENARVPFKLDITSGDSIIPAALMYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGKDNSRMKDFYDLYMIPKLERIDEKNLYKSVQGTFKE
                     RNNQSVFKKLYNQEMPQLMKDEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEKVERKQNFKRSQQMNQEMER"
     gene            1630..2115
                     /gene="ssb"
                     /locus_tag="IVD66_002768"
     CDS             1630..2115
                     /gene="ssb"
                     /locus_tag="IVD66_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP6146932.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTATFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            2137..2394
                     /locus_tag="IVD66_002769"
     CDS             2137..2394
                     /locus_tag="IVD66_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146933.1"
                     /translation="MAKKNSLTMDLLIPVIAFIDGISLGITENLLVNRIAKGSLFLVF
                     VYLVCSYLLKRVGKDNSFWRLTKVTIGATAVILTAILPLYM"
     gene            complement(2554..2676)
                     /locus_tag="IVD66_002770"
     CDS             complement(2554..2676)
                     /locus_tag="IVD66_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HAP6146934.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            2830..3090
                     /locus_tag="IVD66_002771"
     CDS             2830..3090
                     /locus_tag="IVD66_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146935.1"
                     /translation="MEHYTGLLDKIRVIKTQPLLVRFTLHTSHEPINCVVANIEIADK
                     LLILEEGKYTISVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            3533..3733
                     /locus_tag="IVD66_002772"
     CDS             3533..3733
                     /locus_tag="IVD66_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAP6146936.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PICGKKYTLSYGDYILIEEKGR"
BASE COUNT         1397 a          659 c          762 g         1073 t
ORIGIN      
        1 aagaaccagc aacggattca aaaagaaatt gaattagatc gataaatatc tttcttgtta
       61 atataaaact aacgtgatat agttatgtta gttttatatt aactttaggg gaaaagcaat
      121 gaaagacaaa atccagtgca tttttgataa acataatggg aatctatcct tgaaggatgc
      181 tagaagtgaa ggcttatcgc ctatgacgtt agatcgatta gccgaaaagg acaaaataga
      241 aaaggtagca ccaggtttct ataccttaaa agaagcgttc gtggatgaat tgtatctcgc
      301 tcaaagtatc tattccagag gtattttttc tcatgagact gcgctcgatc tttttcaagt
      361 cggaacgtat atccctaaaa agatcaatat gatgtttcct aaaggataca atgtttcaaa
      421 ggagaaatta gacgagtatg ctattcaacc gcattacacg aataaagaaa attttgacct
      481 gggaatcaca gaaacagaaa gcttttacgg caataaaatt ttagtctatg atttagagcg
      541 aacgttatgt gatatgtgga atccaagata caaagcaagc gtagaggtaa aacaagaagc
      601 attaaaagaa tatatgacaa gtaccagtag aaatacaaat aagctaagaa gatacatgga
      661 tattttaaaa tcaccaaaag aaatgacttt gtatatgttg ccactttatt gagaggagta
      721 aaggtgaatg acaccgacac aatttaaagc aaaaacgaga aatttcgcaa cagagaaaca
      781 tttaaatcca caaattgtcc aaagatatta tatgatggaa aaattattag aacgtattgt
      841 tgaatcgcct tatcatgatg attttgtatt aaaaggggga tttctgatcg gatcaaaata
      901 cgggttagaa aaccgttcaa ctgttgatat tgatacgact tatcgaaatt cgaaactaac
      961 aaaagaaaag ttagaaactg ttttttctga gttaacagct gatcccacaa aagatggaat
     1021 tcgatttgaa ttaaagggat taacagagac gagggaagcc gattattacc caggttttca
     1081 agcaaagttt attgcttatc ttgagaatgc acgtgtacca tttaaattag atattacttc
     1141 aggtgattct attattccag cggcattgat gtatgaacac aaattaatgt ttgaagataa
     1201 aacgattcat attccagctt atcctacgga acaaattcta gctgaaaaat tacatgctac
     1261 gtttagtttc ggaaaagata attcgcgcat gaaagacttt tatgacctgt atatgattcc
     1321 aaaactagaa cgtatcgatg agaaaaactt gtataagagt gttcaaggaa cgttcaagga
     1381 aagaaataat caatctgtgt ttaaaaaatt gtataatcag gaaatgcctc aattgatgaa
     1441 ggatgagggg ttgagggaaa agtggaaaag ataccaacaa gaaaattatt ttgccaaaga
     1501 catttctttc gaatctacac taacttccgt cgattctttg atgcaatcaa ttgtagagca
     1561 agagaaagta gaacgaaaac aaaattttaa gagatcacaa caaatgaatc aagaaatgga
     1621 gagataaaaa tgattaataa tgtaacttta gtaggacgat taaccaaaga tccagattta
     1681 cgttatactg caagtggtac tgcagtagcg acttttaccc tagccgttaa ccgaaatttc
     1741 acgaatcaaa acggcaatcg agaagctgat tttatcaatt gcgtgatttg gcgcaaacca
     1801 gcagaaacga tggcgacatt agctaaaaaa ggcagcttga tcggtgttgt cggacggatt
     1861 caaacacgga cttatgacaa ccagcaagga caacgtgtgt atgtgactga agttgtagca
     1921 gataactttc aactattaga aagtaaagca gcgacagaga gccgtgcgca tgcagatcaa
     1981 tcgtccacca gtccaagcac cgccaccttt gaacaacggg atacagcgac gcctaacaac
     2041 aatggattga acgcttcaca gaatccattt ggtggacaat caatcgatat tagcgatgat
     2101 gatctaccgt tttagttcga gaaagaagga gtaagcatgg caaaaaaaaa tagtctgacg
     2161 atggatctat tgatacccgt aattgcattt atagacggga tttctttggg tatcactgaa
     2221 aatcttttgg taaatagaat tgcgaaagga tcactatttc ttgtattcgt gtatcttgtc
     2281 tgttcttatc ttctaaaaag agtaggaaag gataattcct tttggcgatt gactaaagtc
     2341 acaataggcg cgacagctgt tatacttacg gctattctac cgctttatat gtagggttaa
     2401 cgggaaatca ttgaacttct tgcgaaatat tgttataatg aacatgaaaa agaggagttg
     2461 cgcaaacaac ccctcattaa cagcaccgtt taaagaacgg cggctcagat taattattta
     2521 ttgagaaata accgatcctc gctaaagtga cggttatttc tttttgtcat ttttaagcat
     2581 atttacaatc aaactaatca aagcaatggt aaacatacca aaaccaagaa tggtttgaat
     2641 tgtctcatat gcggacaaaa ggcttactcc tttcatagat tttagcactt acattcataa
     2701 gcaccaccac cttccagaag tcgccaccgt cattaaactt tactgtcttg atcattatag
     2761 catatctaaa atcgaataaa aattctcaat tttagctgtt tttgctataa ttttagcgag
     2821 gtgatcgcga tggaacatta tactggttta ctcgataaaa ttcgggtgat caagacacag
     2881 ccattgcttg tgcgatttac attacacacg agtcatgaac caatcaattg tgtagtggcc
     2941 aatatagaaa tagcggataa attgctgatt ttggaagaag gcaagtatac tatttcagtg
     3001 acaggtcact tcaataaacg gaatcaatta gtcattgaat cgatgcaaat tagaaacccc
     3061 gatcatttta cgcgatcgat gggcatataa aagaagagct gcaatcctaa tgtaggactg
     3121 cagctctttt tgttttacat agaaacggga acaggaaaag gcctttttag gaaggcacaa
     3181 gtgccttctc aattgaaaaa cctttctctc actccaaccg ccaccgccgt tcgagaagaa
     3241 aggaagtgaa cgctgcacgt tcactaagat aaggggtctt gcaaagcaag acaaaataga
     3301 aaaaacttcc tctcaccaaa aggttcgttc ctgttcgtta tctctttatt gatttgccag
     3361 accggcaaca agttgccttt tatcaccaaa aagcgacaag gacaagggta aatggcacgc
     3421 tgcgcgccct tgtccttgtc gcttttcgtt gattcattct ggccaacaaa tcaataaaga
     3481 aagaactaac gaaaggaagt aaaacctttc ctaagaggag gcagaatcaa acatgcgaaa
     3541 gaaatttgat tattggggtg ttcccttcag cgaattattc ccaaactatc atgcaccaca
     3601 tactgtcgaa tgcgattgtg gagaaagagc gaaatgtatc aaaagctatc gtttgtatca
     3661 atgtccaata tgcgggaaaa aatatacctt gtcttacggc gattacattt tgattgaaga
     3721 gaaaggaaga taaaatgatg gctcaaaatt actatgacga atttgtcaaa ttacctttgg
     3781 ataaaatggc acaaaaaatg gaggatatga cgttcctata caacgaaaca cgtgttccaa
     3841 aaaaacatta taaagaaaaa ttgtcggtag ctgtggaaga aatgattgaa t
//
LOCUS       DACBZK010000145         3865 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.152, whole genome shotgun sequence.
ACCESSION   DACBZK010000145 DACBZK010000000
VERSION     DACBZK010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3865
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.152"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(248..469)
                     /locus_tag="IVD66_002773"
     CDS             complement(248..469)
                     /locus_tag="IVD66_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146937.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(567..812)
                     /locus_tag="IVD66_002774"
     CDS             complement(567..812)
                     /locus_tag="IVD66_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146938.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            1052..1666
                     /locus_tag="IVD66_002775"
                     /pseudo
     CDS             1052..1666
                     /locus_tag="IVD66_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(2036..3037)
                     /locus_tag="IVD66_002776"
     CDS             complement(2036..3037)
                     /locus_tag="IVD66_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HAP6146939.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(3196..3462)
                     /locus_tag="IVD66_002777"
     CDS             complement(3196..3462)
                     /locus_tag="IVD66_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6146940.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(3452..3808)
                     /locus_tag="IVD66_002778"
     CDS             complement(3452..3808)
                     /locus_tag="IVD66_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP6146941.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT         1222 a          698 c          512 g         1433 t
ORIGIN      
        1 tttttactat atacttcttc ccagaacttg tccgtctcct tcaaattatc tctacctctc
       61 gagttcattg ggtggtttgc ccatttatta aacatggaat cacctttctc atactcatat
      121 atttatgtcc tatttcaatt atatttatat atgcttaaat aaatttgtat cctgaaattt
      181 attgtaatat gaagctgtat tttacatata gtaaccaaag agttaataaa ataaaaagag
      241 cgaaccatta tagatcagct cttttttcat tgctgttttt aatcttatct agaatcactt
      301 caaatgtttc aaaggtattt acatctaact gacataacca aagcaagtac ttcttttctt
      361 tgtaagtcca atcaatatta cggtaagagg acattagatt atggtacctt gctctttgtt
      421 caactgaagc caattcccag cgtttttcaa atattttttc ttcttccatt attgatccct
      481 cgcaagacgc tacctcaaac ttaaataatg ggcagcgaaa gtctaattcc ttagatctaa
      541 gtatagcaaa caaatatgaa aaaaacttag aaggtagtaa aagttcttcc gtcttttgct
      601 ttgcttctat tcttaatgtg tttcgttatc ggtgccctac aaagattttc attaattaca
      661 cactcattta ttgttgtgta ttttctgaca tttctctctt gatcaattat tttaattcca
      721 tgggcatcct gatagttcat aggagaggag cggctatcag aaatagttgc acctatctct
      781 tgaacttctt ttacaacttc tggaaaatcc atccatcctg cttcagctgt caaaagtaat
      841 aatctataat atttatcttt ccttttcaat ctaagaaatc gtcaccccat tctttttctt
      901 ctattataaa ctatttaact tttagaattc aaaaaccgtt tgtctattta gagtttaccc
      961 taaatagaca aaaatataac attgaaaaat ttagagttct aacgtatgat tagggtgtat
     1021 tataaacgtt atagaaaagt agggaataaa tttgaaaatt gcttatatta gagtttcatc
     1081 catcgatcaa aatgaacaac gtcaaattga agaaatgaaa aagtttggcg ctgaaaaaat
     1141 ttttatcgaa aaacaatctg gagcgacgat tagtcatcgg ccgattttcc aggaagcttt
     1201 agattttgtc agagagcaag atatttttat tgtagaagcc attgatcgac ttggacgcaa
     1261 ttatgacgag attatcgatt cagtgaatta tctaaagaag aagaatgtgc gacttattat
     1321 caccagttta ccgatcatgg ctgaagcaat tggaaatcct ctcctagata aattcatcaa
     1381 agacttaatc atttaaatct cagccatgat tgctgaacaa gaacgtactg aatcgaaacg
     1441 acgccaggca caaggaatta aaatcgctaa agcaaacggc gtctataaag gtcgtcctaa
     1501 gttatacagt gcagacacca aagatcctca acgtcgcctt gtctatagga gtatcgttca
     1561 ggatcttgag aatggggttg ctatctcaaa gattgcaaca gactacaatg tgactaggca
     1621 aacaatttac cgaataaaaa aagaaatcga ccaactaatt gtatgatttc ttttttgaat
     1681 cacgtaatta ttaattagct ttgtcatcaa tacagacaat cattttagat tcatctagct
     1741 aagttgatta catttatgtt aaaaagaatt tagttaacat aaatataatt gatgcataaa
     1801 tcgtccttat ttaaaggcat ttaacattga caacttagta taatgtatct tatgtaaact
     1861 aataagattt gaattttatt ttatacacac tcgataatag atcaatttta tggtcccccg
     1921 catttacgat tgcacaagag aaacataaag tcgacctatt agcatttctt ttcaattcaa
     1981 acattaaaaa agtttatacc tctgctacta aaaaatgaaa ttatctattt aaaatttaaa
     2041 acggtaaatc tgattcatcc aaattggaaa atggatcagc ctgtattgga gctttgtatt
     2101 tctccataat aacagatatc tttttttcat tttttaaaaa atacctttta aatttcttat
     2161 agtcctctga aatcaaaata tagcgtgatg gatactcatc aaaagaagaa tcgtattctt
     2221 cctttaaaat tcccgattta cttaattttt ctagtacatc aaatactcta tcactcaagt
     2281 aactccttaa attgttatca ctttcccatt gaactacttt tctataagtt gaattatcag
     2341 ttgaaaagat agaattttca tccataaacg catatattag cagcaatctt tcatcattgt
     2401 caaattctat tggatcaaaa atatctaagt tgtcatcaaa atctttatca gttccggtaa
     2461 cttttttgtt aattactgaa ggtgtcttgt aagaaataga atctaaatca aagcgttttg
     2521 attctaaatt attttgtgct ttctcaatta aataattcac tttttttgtg agaaaccttc
     2581 tgatattgtc tttgctatat gttccataaa aacccttatc ttctaaagag tccctgtact
     2641 tcttaacttc tatatactct tcagccaaaa cttgtggaac tggttcatct aagaaaaaaa
     2701 cccctacctc gcctttgcta tttttataaa agtaatcaat ttctgctata gttcccgatc
     2761 tataattatc aactggagaa cccaacttat ggccaaaaat cgctaataat atatcactat
     2821 tttctacaat ttgtttatta ataacacttt gcccagagct attatttata taagtaggaa
     2881 tcgcattcgt ttcccatcga attggcatca aaattacttt tgtattatct gtattttcta
     2941 tattccatct atatatggtt tcttctactt cattcctctt tgctgctata tcacctggtg
     3001 atgctataaa tacttttatt agatttatgg ttttcattta ttgtaccttt ctctttatgt
     3061 ctctttaaag taatttttgt ataaaattta ttgactttta cactatagga caacttttat
     3121 ctatttagta caaaaaggcc cactaaacta attgattagt taggagccta ttacaggtat
     3181 attttcaact cgcttttaag caaattctac taccagcttt ttgcctaatg ccctagcgat
     3241 atcatcaagt ttatcgaaag atacgttatc ccctctctca attcgagcaa tagtagattg
     3301 agttgtatgt gctttttgtg caagctccgc ttgagttagg cctgcttcct cccgtgcatg
     3361 ataaagagca accgcagttt cgagttttct tccttcacgg tcatatgctt ctgcaaaatc
     3421 tttgtctttt tgcttttctt caatcaattt tttaatcatc atttgtgaac cactcctctc
     3481 taagttcttt tgcatgttta agttcactta ttggtgtttt ctccgttttt ttagtaaatc
     3541 catgggtaat gacatacctt ccattgacca catggaaata gatagctctt tggatgtttg
     3601 atcctacctt acttcttaat tcgtacaaat tagtgtctaa ttttttcacc catttcaacc
     3661 gttgagctac tagcatccca ttcttttctg tttcttctat tgtacgtaaa agcttcgcac
     3721 tatctttttt tggtaatgtt tccaaccatt ctaaaaattc atcatgacca ttaggtcttt
     3781 taaatgtttc aaaagatatt ttttccatac ccaattatat catatattga ttttatatta
     3841 tagtatataa cataaaaatt cgaat
//
LOCUS       DACBZK010000146         3735 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.153, whole genome shotgun sequence.
ACCESSION   DACBZK010000146 DACBZK010000000
VERSION     DACBZK010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.153"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..478
                     /locus_tag="IVD66_002779"
     CDS             <1..478
                     /locus_tag="IVD66_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP6146942.1"
                     /translation="CIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIV
                     SVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAF
                     YYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
     gene            683..2347
                     /gene="alsS"
                     /locus_tag="IVD66_002780"
     CDS             683..2347
                     /gene="alsS"
                     /locus_tag="IVD66_002780"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HAP6146943.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            2360..3070
                     /gene="budA"
                     /locus_tag="IVD66_002781"
     CDS             2360..3070
                     /gene="budA"
                     /locus_tag="IVD66_002781"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HAP6146944.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            3200..3697
                     /locus_tag="IVD66_002782"
     CDS             3200..3697
                     /locus_tag="IVD66_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HAP6146945.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
BASE COUNT         1230 a          597 c          807 g         1101 t
ORIGIN      
        1 ttgcatcgtg atgataggta tgacagaaga attagcaaaa gaaaaaagtt tttcaccagt
       61 acgtttgttc ataaagacgt ttcgccaatt ttggctaaag ggattttttt attggctatt
      121 tgcttggata gttagtgtga taatgatttt tgattgtttc ttttttatac gtttttctta
      181 tggaaaatgg ttgattccgt tgtttgtttt acttgcttgt ttatcagttt cctttagcat
      241 caactactgg tattttcagg tgagaaatcc agcgtcgaaa ccaaatcaag ttctacggat
      301 agcgttctac tatacgttga aaaaatggta cgtgagttta ctagattttt tactattgac
      361 aagtttgttt ctcttctttt tcgtaaagcc ccaatggtgt attctactag gtccttctat
      421 cgtatttggt ttgatttact tcaacaatcg taaattgatg agaactatgg atctgtagac
      481 tttataaatt gaaactttca attaagaatg acagttttta tgtaaaaact gtcattcttt
      541 ttcatttttt gaaacatatg gctaaacaaa tgaaataaaa cgtgctatac ttttgaatga
      601 aacaggttta gaaactgtat caattatttg tgattatttc taactaataa ttaaaaataa
      661 agcataaaaa ggacgatgtt caatggacga aaaaatgaaa caaggttcga aatctgtagt
      721 agaaagtttg attaatcatc atgttgatta tgtattcggt ataccaggtg caaaaatcga
      781 tggtgtattt aatgaattag aggatcaagg tcctgaatta atcgtgactc gtcacgaaca
      841 aaatgctgca tttatggcac aagcaatcgg acgtattaca ggagagccag gagtagttat
      901 cgcaacaagt ggtcctggtg ctagtaactt agctacaggt ttggtaacag cgacagcaga
      961 aggtgaccca gttttagcaa ttgccggaca agtaaaacga agcgatctat tgaagttgac
     1021 ccatcaaagc atggataatg cagcactgtt ccagccaatc acaaaataca gtgcagaaat
     1081 ccaagatcca gaaacaattt cagaagtgat tgccaatgct tatcgtatgg ctaagagttc
     1141 aaaaaaaggc gcgagcttta tcagtatccc gcaagatgta gtggatgcac ctgtccaagg
     1201 gaatgtcatc aagccattga gcgatcctaa attaggttct gcttctgcag atgatatccg
     1261 ttacctagct gaacgcatta gagaagcaaa actaccggta ctattagtag gtatgcgagg
     1321 atcaagtgaa aaagaaacgt tagccatcag gcaattagtt ggaaagacag cattgcctgt
     1381 tgtagagaca ttccaagcag ctggagtgat ctcacgtgaa ttagaagcgc atttctttgg
     1441 tcgtgtgggt ttatttagaa accaaccagg agatatgctt ttgaaacgaa gtgatctagt
     1501 tattgctatt ggctatgatc caatcgaata tgaagcaaga aactggaatg cggaaaaaga
     1561 tgcgcggatc attgtgatcg atgaagcgcc agctgaaatc gatcctttta tgcagcctga
     1621 aagagaattg atcggtgata tctcagccac tcttgattta ttgacaggtt cattagagcc
     1681 tcaacaagtg tcagaagatg caaaagaata tttagcatct cttcaagcag aattaacgga
     1741 gcgggacatt gttcaatcaa aaggagaagc aggtatcttg catcctttag aagttattaa
     1801 cacgcttcag tcaaaagtaa cagatgatat gactgttacc gtagatgtag gtagtcatta
     1861 tatttggatg gcacgccact ttagaagtta tgaacctcgt catttgttat tcagtaatgg
     1921 tatgcaaacg cttggtgttg cattgccatg ggcgatttct gctgcattgg tgcgtccaaa
     1981 tacacaaatc gtatcagttt ccggcgatgg gggattttta ttctctgccc aggatttaga
     2041 aacggcggta cgtaaaaaat tgaatatcgt tcatttgatt tggaatgatg gacactacaa
     2101 tatggtagag ttccaagaaa aaatgaaata tcagcgggcg tcaggtgtag actttggtcc
     2161 agttgatttt gtgaaatatg cagaagcttt tggcgctaaa ggaatccgag ctacaagtgt
     2221 agaggaatta gaaaaagctt tagaagaagg atttgcgaca gaaggacccg taattattga
     2281 tattccgatt gattaccgtg ataatgagaa attgggagaa acaatcttac cagatcaatt
     2341 ctattaagga agtgtcgaca tgactgaaaa aatcttatac cagcacggga cattaggagc
     2401 tttgatggct ggcttgatgg atggaacaga aacgattgct catatattag aaaaaggaac
     2461 tctgggattg ggaacattgc atgggcttga tggtgaagtc atctttttag atggcgtagc
     2521 ttatcaagga agatcagatg gctcagttgc ccaattagat ggaagtgaac ttacccccta
     2581 tgcagcaatt acagatttta cgccagatac tagtttttct gtctcaaaaa ctgcagatgg
     2641 agaacaattg aaaaaagaca tattagtaag agaagccggg gaaaacctat ttttggcagt
     2701 gaagataact ggattattca aaaatatgca catccgtatc atgccgaagc aagaaaaacc
     2761 ttacagaaga ctagcaaaaa tttcagagtc tcaaccagaa ttccaacaaa gcaatgtcca
     2821 aggaacatta gtcgggttct ttacgcctga attattccaa ggagttgctg cagcgggatt
     2881 tcacttgcat tttatcgatg atacacatac atttggcgga catgtaatgg attttgaagt
     2941 ggctgaagga aaagttgaga ttagccgcat ctcgtccctt gtacagcatt ttccagttga
     3001 tgatccgact tttgttcacg aaacgattga ttatgctgat ttagcagcag aaatccaaca
     3061 agcagaatag aaaaagacag cgagatgcgt tcaaggtgat taacctgacg tatctcgttt
     3121 ttttgaggag gaaacctagc gtttacaaaa aaactgagct ataatcttct ccatagatca
     3181 aaaaggagcg gtttttatca tgtggacaga aaaacagaaa aaagatgcat acgaaatttt
     3241 attattacag caacaaggat tattagaagc agaagataac tggttagcaa atttagcaaa
     3301 ttcatctgca ttgttgaatg agactttgcc tgagactgtc tttgcaggat attatttatt
     3361 cgatggtaat gaattgattt taggaccgtt ccaagggcga gtttcttgca cacgtatcaa
     3421 gatgggaaaa ggagtttgtg gagaatcagc tgaaaaacaa gaaacattga tcgttgatga
     3481 tgtcaaaacc catgcaaatt acatttcctg cgattcagcc gcacaatcag aaatcgtagt
     3541 gccaatggta aaagaaggta atttaatcgg tgttttagat atcgattgcg gagtaacgaa
     3601 agggtatgat gaaatcgatc aagcatttct agaaaaatat gtagatcttt tattagcaaa
     3661 ttttaatata aatgcttttt catttattaa taactaaaat cgtctattga aacaaaaaag
     3721 aagagaaatc aagaa
//
LOCUS       DACBZK010000147         3578 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.154, whole genome shotgun sequence.
ACCESSION   DACBZK010000147 DACBZK010000000
VERSION     DACBZK010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.154"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..523
                     /locus_tag="IVD66_002783"
     CDS             <1..523
                     /locus_tag="IVD66_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146946.1"
                     /translation="EKAIPYIAAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTIS
                     NEINQYREREPEIQPAEVKQEHKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTL
                     HLKDAAFIEDPQHNQVILKGKSYGKEIQTALPSEEFALGNSFRFSLETVSEVAKRKNE
                     IYYEQQLSQKERV"
     gene            584..2044
                     /locus_tag="IVD66_002784"
     CDS             584..2044
                     /locus_tag="IVD66_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAP6146947.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGLAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQGIGGDIIELTQLFFIDDSIQNPKQRFKAALDYIIKDENKVERVEN
                     LHFETQEYKHHPIDYRPLTEKGRSYLKEQRKFPEWLIDYGEQQGLILEMKPRNERKNY
                     IVQDDRLDYAIVFPWKDRHTDQILGATYQGTIVDYERFGKRGVDKRIDINPTPNHGFN
                     VLLGSPKNLKFFESPIDLLSYAALNRETIKDTWLVSMDGLKDAVVGHYVREAVTELAP
                     KEEFPESIEICVDNDRAGHVFWDKVHRLGVSNPFTGKAVYFEPNLPNDWQVPREYQTI
                     YEEVGKEMRVAPEAIMAIHKIENNLTDTNQIVSFGEIQGVFAKKLAPKEKAQSIVVKE
                     KCIEAAQQLKSCEKSDGTYDFDRFYRGKGKINEQIQFSLKAKHYFEGYKNHEHEFVSE
                     VKKDWNDQLKHEIQQQAIRKQKRAMLFQQGRQQERE"
     gene            2055..>3578
                     /locus_tag="IVD66_002785"
     CDS             2055..>3578
                     /locus_tag="IVD66_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP6146948.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDEKWKQWSLAHLPIFPNQYHYHVPKDKKKQFNVVKRQLQSADT
                     VVIATDSDREGELIAWSIIQQAGADQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAHVITQNGAFDAKLDPNETQATQEAFEAYLKDKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEEKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPVDLGWKKLFGK
                     ESDGKEKEEEPLLPKVAKGEMVTVDLQVLEKETKPPKPYTEGTLITAMKTAGKTVDSE
                     "
BASE COUNT         1287 a          612 c          802 g          877 t
ORIGIN      
        1 ggagaaagct attccttata ttgcagcatg gacgaagaat ggtcagacgt tggatgataa
       61 ggaagctgcg gaacgtggga aaatcatgaa tgatgtcagc cgtgtcgcaa atgaattcat
      121 tcaaaccatt tctaatgaaa tcaatcaata cagagaaaga gaaccagaga tccaaccagc
      181 agaagtgaag caggagcata aaaatactgt agaaacggca gaacaaaaga atattgtgcc
      241 tgttggttca ctttggatcg acaagaaaga cgggaaagta atggaagaag atacgggtcg
      301 aacgttacat ttgaaggatg cggcgtttat tgaagatcca cagcataatc aagtaatttt
      361 aaaaggaaaa agttatggaa aagagatcca aacggcgtta ccttcagaag aatttgcgct
      421 aggaaattca ttccgatttt cacttgagac agtgtcagaa gtggcaaaac gaaaaaatga
      481 aatctattat gaacaacaat tgtcacaaaa agaacgtgta taaaacaagt aaaaaagact
      541 atctgaaaaa cggatagtct tttttctttt gggaggtttt aaaatgaccg agaaaaaaat
      601 gagtcttatt gatcgatgta aacagatcga tatagtggat tttgctcgaa acaatggttt
      661 agcggtagtc aataaaggac gagactatcg tttagaagac catgattctt ttgttttcga
      721 tcgaagaaaa cagcgatttt attggaacag tcaaggtatt ggtggggata ttattgaatt
      781 gactcaattg ttttttattg acgattctat tcaaaaccca aagcaacgtt ttaaagcagc
      841 gctagattat attataaagg acgaaaataa ggtggaacgg gtggaaaatc ttcactttga
      901 aacacaagaa tataagcacc acccaattga ttatcgacca ttgacagaaa aaggacgaag
      961 ttacttaaaa gaacaacgaa aattccctga atggttgatt gattacggag aacaacaagg
     1021 gttgatcctg gaaatgaagc cacgcaatga acgaaaaaat tatattgtgc aagatgatcg
     1081 cttagactat gcgatcgttt ttccctggaa agaccgtcat acagaccaaa tattaggggc
     1141 aacttatcaa gggactatcg tagactatga acgttttgga aaacggggtg ttgacaaacg
     1201 aatagatata aatcctacgc ctaatcacgg gtttaatgtt cttcttggat ctcctaagaa
     1261 tctgaaattt tttgagagtc ccattgattt acttagttac gctgctttaa atcgcgagac
     1321 gatcaaagac acgtggcttg tttctatgga tggactgaag gatgcagtag tggggcacta
     1381 tgttcgagaa gcggtgacag aattggcgcc gaaagaagaa tttccagaat cgattgagat
     1441 ttgtgtggat aatgatcgag ctggacacgt attctgggat aaggtacacc gacttggtgt
     1501 gtcgaatcca tttacaggaa aagcggtgta ttttgaaccg aatcttccca acgattggca
     1561 agtaccgaga gaatatcaaa caatctatga agaagtaggg aaagaaatga gagttgcgcc
     1621 tgaagcaatc atggctattc ataaaatcga aaacaaccta acggatacta accaaatcgt
     1681 atcgttcggt gaaatccagg gagtatttgc caaaaaactt gcgccaaaag agaaagccca
     1741 atctattgtt gtaaaggaaa aatgtataga agcagctcag cagctaaaat cgtgtgaaaa
     1801 atctgatgga acatacgatt ttgatcgttt ttatcgtgga aaagggaaaa ttaatgaaca
     1861 aattcaattt tcattgaagg ccaaacacta ttttgaaggt tataaaaatc atgaacacga
     1921 atttgtttct gaagtgaaaa aagattggaa tgatcaattg aagcatgaga tccagcaaca
     1981 agcaatcaga aagcaaaaac gtgcgatgtt gtttcaacaa ggcagacaac aagaaaggga
     2041 gtgaaatcgt catgatgaaa accgttattt tagcagaaaa accgtcacaa gcgaaggctt
     2101 atgccgatag cttttctaaa gctacccgaa aagacgggta ttttgaaatc caagatcggt
     2161 tgtttccagg agaaactgtg atcacgtatg gttttggtca tttagtcgag ttagattcgc
     2221 ccgatatgta cgatgaaaaa tggaaacaat ggtcattagc gcatttgcct atttttccaa
     2281 atcaatacca ctatcacgtt cctaaagata agaaaaagca gtttaatgtc gtcaaacgcc
     2341 agctgcagtc agctgataca gttgtgatcg cgactgatag cgatcgtgaa ggggagctga
     2401 ttgcctggtc aatcattcaa caagcaggcg ccgatcaagg aaaaaccttt aaaagacttt
     2461 ggatcaactc cttagaaaaa gaagccattt atcagggatt ccaacagtta cgagacgcag
     2521 aagagaccta tccaaaattt gaagaagcac aagcacgtca gatcgccgat tggttaattg
     2581 ggatgaatgg tagcccactg tatagtttac tcttgcagca aaaaggcata ccaggaagtt
     2641 tttccttagg cagagtccaa accccaacgc tctacatgat ttatcaattg caggaaaaga
     2701 ttagaaactt ccaaaaagaa ccatattttg aaggaaaagc tcatgtaatc actcaaaatg
     2761 gcgcatttga tgcgaagctt gatccgaatg aaacccaagc gacgcaagaa gcatttgaag
     2821 cttatttaaa agacaaaggt gttcaattag gaaaacagcc aggtacgatc cttcaagtcg
     2881 aaacagagaa aaaaagtgcg gctagcccac gtcttttttc tttatcgagc cttcagtcta
     2941 aaatgaatca actcatgaaa gctagtgcca aagatacttt ggaagccatg caagggttgt
     3001 atgaagagaa atatctaagc tatccgcgaa cggatacccc ttatattacg gaaggggaat
     3061 atgcgtatct gttggatcac ttagacgaat acaagcattt tttgagggct gaagaaattc
     3121 caacccctat tcatacgccg aatagtcggt atgtgaacaa taagaaagtc caggaacatt
     3181 acgcgatcat tcctacaaaa acggttatga cagcagcggc ttttgaacaa ttaagtccac
     3241 tgcagcaggc tatttatgaa caagtgttaa aaacaacggt ggccatgttt gcggaaaagt
     3301 atacctatga agaaacaacg atcttgacgc aagttcagca gcttcagtta aaagcaatcg
     3361 gaaaagtgcc ggtagatcta ggttggaaga agttatttgg aaaagagagc gacggaaaag
     3421 agaaggaaga agagccgcta cttcctaaag tggcaaaagg agaaatggtg acggtagatc
     3481 tacaagttct tgaaaaagaa acaaagccac caaaaccata taccgaaggt acgttgatca
     3541 cggcgatgaa aacagctggg aaaaccgtgg atagtgaa
//
LOCUS       DACBZK010000148         3522 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.155, whole genome shotgun sequence.
ACCESSION   DACBZK010000148 DACBZK010000000
VERSION     DACBZK010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3522
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.155"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            217..492
                     /locus_tag="IVD66_002786"
     CDS             217..492
                     /locus_tag="IVD66_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146949.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            534..956
                     /locus_tag="IVD66_002787"
     CDS             534..956
                     /locus_tag="IVD66_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146950.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAEERVE
                     GKIKSNQTKKYSSKLKKPVNESVHTRVDPFDPTKILKR"
     gene            975..2567
                     /locus_tag="IVD66_002788"
     CDS             975..2567
                     /locus_tag="IVD66_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146951.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVISHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEIENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPEKRSEWNYGDENRTKLSPFTRGKLDELTKYVLTKEPGYQEYIQ
                     ISKALKEEAKSLYGESKRETKNAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVN
                     QMQSIYNERSFRTLKQLPTNEYKYSYQEFVKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            2579..2914
                     /locus_tag="IVD66_002789"
     CDS             2579..2914
                     /locus_tag="IVD66_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146952.1"
                     /translation="MKQYLDQWKVIEGSLKEERIEQLPDCLEKEHLFQISEMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEINEEGINNFPCESI
                     EESISLTEC"
     gene            3061..3255
                     /locus_tag="IVD66_002790"
     CDS             3061..3255
                     /locus_tag="IVD66_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146953.1"
                     /translation="MTQTTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGNI
                     LTLNLTTKMFVDAVENYPFV"
     gene            3287..>3522
                     /locus_tag="IVD66_002791"
     CDS             3287..>3522
                     /locus_tag="IVD66_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146954.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNNQFQKLFDHQKLTNGQ
                     PMNDKRNGRSWFNQQEKIENKIQSLREEIKQQEK"
BASE COUNT         1438 a          500 c          688 g          896 t
ORIGIN      
        1 atcactttct cacgaaaggt gttaggtagg ctgtgcctac cacgtttcta agaaagataa
       61 atgatatcaa aattttggat ttgtgtgtag atttgtgggt aggatgaaag cgaatgtggg
      121 cagtaaaata agcgtttgtg tgtagcaaaa tcaaaaaatg tgtagggata tgtgtagcta
      181 cacatatccc tacacataat aaatttggag gaaaatatgg acttattaat tagaaatatt
      241 gaagaaaagt atattaataa aattgacaaa cgttgtgaag aacttacggt caagactggc
      301 aaaaaatgga gtcgaaatca atacctaaaa gttttgatcg aaaatgattt tgatcacgct
      361 cttctgaatt ataaaaaaga ccaatttgat cggttgttag aaaaatttgt ggatattcaa
      421 acttataata cgaaaacttt agaagaatat attgcaacaa ataatcaatt aattggtttg
      481 ttaattgaat aataaaaata gtattgtgaa tttataaaag gaggaaatca attttggcaa
      541 aagcaacaag aaaacatgta tatctttacg atatgcatat cgaagtactt gatgaaataa
      601 tttctactca tgaagatata tctaattata gtgaagcagt cagacatttg tgtatgatgt
      661 atgatccaaa aatcgaagaa aaaataaatc caattcaaat taaattgaat gcaatgggaa
      721 aagaaatttc tattttaacc gaaatggttt cagagtttgc ggatcttcat ttgaaagata
      781 caggaatact aattggtaca aattcaactg tttatcaaga agcagaagaa cgtgtggaag
      841 gaaaaattaa atccaatcaa accaaaaaat attcttctaa gttaaagaaa ccagtgaatg
      901 aatctgttca taccagagta gatccatttg atccaacgaa gattctaaaa agataaaagt
      961 agaaggagaa cgtgatgaat aaatcgcctg cagttattct tacttgtcaa tttaccttgc
     1021 ccaataaaaa atctttttca acatacattg attatatgac aagagaaaaa gcactggaag
     1081 aaatggaacg acgtacgccc gaagaagaac aggaactgca acgaatcaag aatgctttag
     1141 aggattttta tattcctgaa ggagaaactt tttcggaaag taagacggat aaagaattca
     1201 gtgaaacgtc gaatgaagct caatcgttga tggaacatgg aatcaatttt gacaagttag
     1261 aggaacaaga ttttaccaaa tatctttctt atatgacccg tcactatgcg ttagaacaaa
     1321 agaaagaact gacgcaaagg gaacaaaaag aataccaacg gttgaaccaa gcaatgaaaa
     1381 aatatcaaac agagccacat aaaaaagctt caggaaatct tcctggagtt ttttctatgg
     1441 cttcagacga agtgaaagga agtgatctga aggagatcaa acaaatcttc caaagaggac
     1501 aacaaaaagg ctcaatcatt tatcaagatg ttatctctca cgacaattcg tatcttgaaa
     1561 aaatgggctt gtacgatccc aaaacagata ccttagatga agaaggtttg aaagcagctg
     1621 gaagaaaaat gatggagaca ttattcgaga aagaacaatt gaatgaaaca ggttactgga
     1681 tggcaacgat tcaccgtaac actaagcata tccatattca ttttgcagtt gttgaaaaag
     1741 aaaatacgcg taaaccgtat actgagattg aaaatggtgt gagttatatc gtaccgaagg
     1801 ggaagagaag acaagcaaca ttagacgcaa tgaaaaccaa ttatgtacat gagttagaac
     1861 gtttctctta tgaaaaggat cgaatgatcg gtatggagaa acgaaattta ttgacacgaa
     1921 aaagtgattt gcgtaacacc ttaacaaaag tagtaaaaga accagcacgt tacgatcgac
     1981 acgccatgaa cttattaaat gaagtatata aaaccctacc tgaaaaacgt tcggaatgga
     2041 attatggaga tgaaaatcga accaagcttt caccatttac aaggggaaaa cttgatgagt
     2101 taaccaaata tgttttaaca aaagaacctg gatatcaaga atatatacag atttcaaaag
     2161 cattgaaaga agaagccaaa agcctttatg gggaaagcaa aagagaaaca aagaatgcag
     2221 aaaaaaacgc cctctttgat ttaaaaaagc gcacaggaaa tgcgatttta acagaactga
     2281 agagacagga tagtcaaata aaaccattaa tagaaagtgt caatcagatg caatctattt
     2341 acaatgaacg atcctttcga acactcaaac agttgccaac aaatgaatac aagtatagtt
     2401 atcaagaatt cgtaaagcgt aggaaacaat tccaacaaag agttgtcacg cagcgaagct
     2461 tgcgtcaatt aaatcgaaca attaatgcac atgaagaaaa ataccacgca agtaaagcat
     2521 atgaagagca acagcgaaga atccaaatgg aacaagaaag acaataggag gaagagaaat
     2581 gaaacaatat ttagatcaat ggaaagtcat agaaggatca ctaaaagaag aacgaatcga
     2641 acaacttcct gattgtttag aaaaagagca tttgtttcag ataagcgaaa tgttgagaaa
     2701 cgaacagttt gatccaaatc aatttttagt tgttgagtac ccagctactg gtgtgtattg
     2761 ttgtaatcat gtgaagggtg aaaaatattt tattattcaa gaatacgaag gtaagttagc
     2821 gccttattat actacttggg aaataaatga agagggaatc aataatttcc catgtgaaag
     2881 cattgaagag tctatttctc tcacggaatg ttaaataaat agagacgtaa aagagtcctg
     2941 aacgtgattg tccaggactc tttttcaatg aattgttttc cgccaattca ctgagtggtg
     3001 cgattcaatt ttattatatc aaaagaaagt gagattccaa agtgaaggga ggaagaagaa
     3061 atgactcaga caacgattgg tgttgtggtt gaaaaaagca gggataatct cgtttttgtg
     3121 acagaaattc aaacaggtag agcttttgta gtcacagaca aagctgcaaa agcgtatcaa
     3181 aatggcaata ttttaacgtt aaatctgact acgaagatgt tcgttgatgc agtagaaaat
     3241 tatccatttg tttagacaaa cgatatttta caaggaggaa acggacatgg cagaagaaaa
     3301 agaaccacta gataatagtc ggttgggaaa gtccaaaaga aaattagtac ggttgcaaaa
     3361 cgaattaaat aatcaatttc aaaagctatt tgatcaccaa aaattgacaa atgggcaacc
     3421 aatgaatgac aaacgaaatg gtcgttcatg gtttaaccag caagaaaaaa tagaaaataa
     3481 aatacaaagt ttgagagaag agatcaagca acaagaaaaa ca
//
LOCUS       DACBZK010000149         3460 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.156, whole genome shotgun sequence.
ACCESSION   DACBZK010000149 DACBZK010000000
VERSION     DACBZK010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.156"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(578..1594)
                     /gene="tsaD"
                     /locus_tag="IVD66_002792"
     CDS             complement(578..1594)
                     /gene="tsaD"
                     /locus_tag="IVD66_002792"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HAP6146955.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(1591..2055)
                     /gene="rimI"
                     /locus_tag="IVD66_002793"
     CDS             complement(1591..2055)
                     /gene="rimI"
                     /locus_tag="IVD66_002793"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAP6146956.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2062..2604)
                     /gene="rimI"
                     /locus_tag="IVD66_002794"
     CDS             complement(2062..2604)
                     /gene="rimI"
                     /locus_tag="IVD66_002794"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAP6146957.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(2588..3412)
                     /gene="tsaB"
                     /locus_tag="IVD66_002795"
     CDS             complement(2588..3412)
                     /gene="tsaB"
                     /locus_tag="IVD66_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HAP6146958.1"
                     /translation="MYYCTSFAFGIFILRIKKYATMEGENVIAERIKYMITLGIDTAN
                     QTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAIDQLFADLQISPKDIDRIAVSDGPGS
                     YTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAANCIGVDNIIVPMFDARRKNVYAGAY
                     RWKENRLETVLEDVHISASDLFTQLQKLNEAIYFVGSDCHKFFSEIKEILPSAMINTV
                     PAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKRVEAEEKWLETHTPGDESYVEKI"
BASE COUNT          989 a          757 c          594 g         1120 t
ORIGIN      
        1 atatcagggt cactgcttat tttcctccct aaaacttctg aaagatccgg cagttttaga
       61 tcactggaca agactcaaag attttctatg tgtgtttcag ttatgtaata ttcactgttt
      121 gcaaaaaata ctgttagatt aactagatga agcgtcttgt cctcatccga tctagattat
      181 tcgatattcc tcgacaataa acgattactc agtgagggca atcagaggaa cggataatga
      241 taaataagct gtaaaaaata gcaaaataac aataatgatt aaaagtatgt aaaaaatagg
      301 gctttgacaa aaacgtgtca cagccctatt tcgattaaac ggtgtgtacc tgtcaactct
      361 tcggtcacaa gtcataatgt tcataaacat gaggagctgt tttttgaaat tgttccttgt
      421 gaatcagagt taaacgacag gcttacgaac tcttgattaa acggcgttca aaagcttgca
      481 tacgcggtaa taagaacagc caggtcaaaa acatgagaag ccgtttttcc tgggctgttc
      541 ttattacttg atgcagggca gctttttcac aacctcttta ttcagataaa accaagcttg
      601 gatcagcatt caactgatag ctagcaaaat ttcttttttg catttccaca tgtgctgctg
      661 ctccaatcat tgcagcatta tctccacaaa gtcgaagagg gggaatcact agttctacct
      721 cagggagttt agttgccaaa gcatcctgca atccttcacg caacccttga ttggccgcta
      781 cacctccagc tataatcagt tgcttgactg gataattttg acaagctcga agtgttttag
      841 taatcaatac atcgatcaca cttgcttgaa agctagctgc taaatcattt ttgtctagat
      901 cttctccacg ctgttgtgca ttatgcacca aattgataaa tgcacttttt aatccgctaa
      961 aactgaaatc ataattatct tcatggatca tcgctcgcgg aaaatggtaa ttatcttttc
     1021 cctgatgagc tagctgatcg atttcttttc cgcttgggta agaaagacct aatactcttc
     1081 caactttgtc ataagcttct cctgctgcgt catctcttgt ctccccaatg atttcatatg
     1141 atccatcttc ttgcatatag actaattctg tatgtcctcc gctaacaaga agtgccatca
     1201 atggaaactg gaatggttta accagacggg ctgcatagat atgccctgcc atatggttta
     1261 caggaataag cggcaattgg tgtgcccaag caaaagcctt agctgcagaa ataccaatca
     1321 gcaacgagcc gacaagtcct ggtccataag tgacagcgac tgccgataaa tcttctgccg
     1381 acacaccagc ttctaccagt gcatcttcca agcataaggt gatttgttct acgtgatggc
     1441 ggctagctac ttcaggtact acgccaccaa aacgtttatg actgtttatt tgagaagcaa
     1501 cgatgttaga taagatctct gttccatttc taacgaccgc tacactcgtt tcatcacaac
     1561 ttgattcaat cgccagaatc aattcttcat tcatttcatc gtctccgttt ttaactttct
     1621 gctcataatg atcgcatctt ccgtcggatt gcgataatat gatttccgtt tacctaatat
     1681 acgaaacttt tctgattcat aaagttttct tgctgcttca ttagatagac gtacttctaa
     1741 aaaaacatgc agcgaatctt ttatttgttc cgtaatcagt aattgtaaca aatgccgtgc
     1801 atgccctttt ccttgttctg aaactgcaac agcaatattt gtgatctcga cttcatctat
     1861 tactttcgag tatccaataa agccacagat ctggttatct tcagctaaaa gcagataatc
     1921 agagtgaggc tgttggatgt ctgccaaaaa ctgcattttc gtccaaggtg aaccatgtgg
     1981 ataagcattt tcgctaatca tccatacgca ttctgccaag tacgcttcat caaaatcttt
     2041 ttttctgcaa atcaactaat ctcactcatt ttctaaaagt tttatcatat ccaacgcatc
     2101 ttcttttgtt tcagtgtaat atcttttttt gatcgttgtt gcttgaaacc ccaatttccg
     2161 ataaagtctt tgtgcatctt gattactcat acgcacttct aatgacatcg tctcacagcg
     2221 attcattata gcaaagttct cgatttcgtc aataagcagc gaaccgattc gtttacgctg
     2281 atatgccggt cgaacggcaa tattcgtgat atggcaatct aaaccgaacg ctcttgaacc
     2341 gataaaacca atcattcttc cattatcaaa gatacctaga tatagatgag gaagcggtga
     2401 cttcaattct gatataaagg cactttttgt ccatggcaat tcgccattat agacttctcg
     2461 ttcgacatcc agcagctctt tgatatcttc tgtagtcaat tctcttagta cgtaacgacg
     2521 atcgatttgt tcgactgttt tttctgtata aatcatttta tcttgaaaaa agcttctggc
     2581 atacgctcta aattttttca acataacttt cgtctccagg tgtgtgcgtc tccaaccatt
     2641 tttcttctgc ttctactcgt tttaaatagc gaggaagaaa agcttgtttc tctgcaactg
     2701 gttcaactaa agcacctaat tgagccacag ttacaccact tggaatatcc catgctggaa
     2761 ctgtattaat catcgcacta ggcaatattt cctttatttc agagaagaat ttgtgacaat
     2821 cactcccgac gaaataaata gcttcattca gcttttgtag ttgtgtgaac aaatcagaag
     2881 cagaaatatg tacatcttca agtacagttt ctaatctatt ttctttccag cggtatgccc
     2941 cagcgtatac attttttctt cgagcatcaa acatgggcac aataatatta tccacaccga
     3001 tgcaattagc cgcgatggtt ttcagactag atactcctac tagctcttta tctaatgtat
     3061 aagcaatcgt ttttgctgtc gttacaccta tacgaagccc tgtataagaa ccgggaccat
     3121 cagaaaccgc gattcggtca atgtcttttg gacttatttg aagatctgca aacaattggt
     3181 cgattgcagg catcagtgtt acactgtggt tgcgtttgat atttgtttgt atttgtccaa
     3241 gaatttgttc gtcttctacc acaccgatcg ccaaagtttg gtttgcagta tctattccta
     3301 atgtaatcat atatttgatc ctttctgcta tgacattctc gccttccatt gtagcatact
     3361 tttttattct gaggatgaaa ataccaaagg caaaactagt acaataatac atgattatct
     3421 gctggcgggc aaattttgcc ccttcctgaa acacaaaaaa
//
LOCUS       DACBZK010000150         3456 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.157, whole genome shotgun sequence.
ACCESSION   DACBZK010000150 DACBZK010000000
VERSION     DACBZK010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.157"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..1155)
                     /locus_tag="IVD66_002796"
     CDS             complement(<1..1155)
                     /locus_tag="IVD66_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6146959.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
     gene            complement(1158..3407)
                     /locus_tag="IVD66_002797"
     CDS             complement(1158..3407)
                     /locus_tag="IVD66_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAP6146960.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
BASE COUNT         1123 a          649 c          494 g         1190 t
ORIGIN      
        1 tctagtattt tttttatttg tcgcaaaaaa tgttacaaat aggatcacaa taaatattcc
       61 tgcgaataca aaaaatggag cagtcaaatt tgtacttctt gttagaaatt gtgctaattg
      121 catagcaata ggagctataa aattaccaat attacagcca ataaaaatca atgaagtagc
      181 aaaattaatt gtattctttg tagtgacttt atctaagtta ctaaagataa atgggaagca
      241 ccatgatcct gttatacttg ataaaaataa acccgttagc aggaacgtca tattaccgtt
      301 tgacacagca attaacaaat ttgaaattat aaagaatata attcccaagt atagggttcc
      361 ttttcctatc cacttattta ttggtccaaa cataaatcct gctagtattc ctaagatagg
      421 cattagagct aaatagttac tagcattaaa gtttacccct ttaatttcag ttgcaattga
      481 tgcaaatcgt acagaaatag caatactatt cattacgagt aagattgcaa atagaactag
      541 ggcaaaaacc attggattca tcttttcttt tacatgattt tcaggtatgt cactattttc
      601 atctctaatt tcaggaactt ttagcgcgaa taagagagct acaggaaacg caattgcata
      661 gactaaaaac gaagccgtcc aattaatgtt cactaaaact ccagcaagaa aaataaggat
      721 tgtctgacct aaagcttcca ttgaatttct aatacctaat agcgttgctc tagtattgcc
      781 agagtataaa gagctgatat atgtcacagc caatgaatta tatactccta aaccggcacc
      841 taatattact cgactaataa gaacggtttg gaaggtagct gtaaatactg gaataattcc
      901 tcctatacca gctaataata aacctaaaat tattgtcttt ttcattccta ttcttttggc
      961 aaagtaacta gataataaga taaacaaaat aacagttata cttggtgcag ttcctaaaag
     1021 ttcactttga ctttgtgata tccccaaaga ctgtttcatt tgtggaataa caccattaat
     1081 tgcttgagag cttgttaaca ttagtgaaat acttaagatt gctccttttt gaagtaagct
     1141 tttttggtta ttcatctcta cttttcctcc tgtgttataa cccaaatctt ggaatcaaaa
     1201 tcaaatgttt ctgggcgtcg attctgatca tttatttgtc cactagatgc atctgaacag
     1261 actagtcctg ctctcatcaa ttccattcca gatcgcaaac tattttgtcc tacattataa
     1321 agtccgtcat tatctaaccc ttttaatttc agtcggcggt aaggagcatt tacctcattt
     1381 aatgttttat aatgagcaac aatagccgtt ttcttatcat gactaacaac catccacgcg
     1441 gtttgattat catcatcgaa tggtgataat agtctataaa aagtaccatt atgaattatg
     1501 gttctatatt ttttataaaa ggcaatttgt tcttttacaa tcctcaaatc gccttcactt
     1561 aattcattta agtcaagctc atatccaaat gcaccaaaaa aagctacatt tcctctagtt
     1621 tttataggtg ttatacggtt tgtttgatga tttggaacaa ttgatacatg agcaccaata
     1681 gacgaaagag gatacagcat actagttcca tattgaattt ttaacctttc aattgcatct
     1741 gaatcatcac tagcccaagc ttgaggtgca tagtgaagca ttccaggatc aaagcgccca
     1801 ccacctgatg aacaagactc aaatagtatg ttaggatatt ttgttataag tttttcatat
     1861 aagcgatata cgcctagtac atatctgtgg aatacttctc cttgttgatc tgctgacaag
     1921 tgactgtcaa atacatcagt caatggacga ttcatatccc acttaatgta atctaagttt
     1981 gattcatcaa tgattttaca catttgatcg aaaatatttt caacaacctc atctaaccca
     2041 aaatttaata catattggtt cctaccatga ttaggttttc gattaggtgt agaaataatc
     2101 caattcggat gtgtgcgata taactcacta tccttattca ccatttcagg ttcaaaccat
     2161 aaaccaaatt tcataccaaa actacgaatt ttttctgaaa ggctgccgat tcctctaggt
     2221 agtcttttag gatttacatg ccaatctcct aatcctgcac aatcgttttc tctttctcca
     2281 aaccagccat catctaatac aaataattca ataccaacat caaatgcttt tttagcaata
     2341 tttaccaact tttcttcgtc aaaatcaaaa tatgttgctt cccaattatt aattaagaca
     2401 ggacggtctt tttctcgcca cttaccacga gctaagcgtt ttctaaatag ttgatgaaaa
     2461 gtttgactca tggcatttaa acccttactt gaataaacca gaatcgcttc tggtgctgta
     2521 aatatttctc ctggattgag tttccaatta aatccaaatg gattgatgcc aacttgtagt
     2581 ctagtaacat cccatgtatc tacttctgct tgaattaaga agtttcctga gtaaactagt
     2641 gctgcaccaa tagcttctcc ttgattttca tcagtatttt ttctttttaa agtaacaaat
     2701 gggttatgct gatggcttga aatacctcga gtagattcga ttgattgaat tccttgttgt
     2761 aaagtacgcg acttaatagt tctttctcta ccccaagcac cagataattg ttgccattca
     2821 taatttgcat cgggtaaatc caatgataaa ctgctaatat tctcgattat ttgaatatct
     2881 tttcctttat tcataactcg cgcgctacga gtaataacag gataatctct ataaattgta
     2941 tataataatt ctacttgaac atttgtaact gaatctaaaa tataaacttt caatgttttg
     3001 ctttcatcat tattatcaac ataggtagca ggtaaacctt ctagtttagg ttttccttct
     3061 tccacttcgt acccttgata gacaaaatct gataagcgag agccattttt ctgtagtaat
     3121 gaaatagcag gatgtctaaa atctgttgta ccatattcag gaaattcttg ttttaagtgc
     3181 tctaacgaat atagcaaatc gttttcattt ctataggttg tcataggccg atgatgcatc
     3241 tcaattagat gactatagtc attatctggt aagttctcac cataatataa atgcaataat
     3301 ttaccatctt ccgatatctt aaaaatgtaa cttatctcct gattaaacaa atgaaattgt
     3361 tggttttctg atcgataaat aatattcatt tcattatcct tatacataag ctctcctccg
     3421 tttctttatt gcattataaa aaacgctcac ataaat
//
LOCUS       DACBZK010000151         3437 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.158, whole genome shotgun sequence.
ACCESSION   DACBZK010000151 DACBZK010000000
VERSION     DACBZK010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3437
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.158"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..1578)
                     /locus_tag="IVD66_002798"
     CDS             complement(<1..1578)
                     /locus_tag="IVD66_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAP6146961.1"
                     /translation="MLDVIKTAFSTQSNQKVIDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLAFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRL"
     gene            complement(1600..2193)
                     /locus_tag="IVD66_002799"
     CDS             complement(1600..2193)
                     /locus_tag="IVD66_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146962.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            complement(2194..2526)
                     /locus_tag="IVD66_002800"
     CDS             complement(2194..2526)
                     /locus_tag="IVD66_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146963.1"
                     /translation="MDKYIHMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWLAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            complement(2604..3146)
                     /locus_tag="IVD66_002801"
     CDS             complement(2604..3146)
                     /locus_tag="IVD66_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146964.1"
                     /translation="MEDILIATFITALGAFLTIFVVTIKGFKDTDSLQKDHQSILDGQ
                     KTHTESIIVHLSEGFTYLKDAMPTFTVKLTEIFHSVEQISSELKEQRQQKDRQLGSLN
                     FRQETIQESLENVNRLNDEMQRVHLENEELRAQNYDLIQKKRNLEQKIVELKEENRQL
                     NYQLRRGKNRSRDLGNELEL"
     gene            complement(3207..>3437)
                     /locus_tag="IVD66_002802"
     CDS             complement(3207..>3437)
                     /locus_tag="IVD66_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146965.1"
                     /translation="NLTTVSYNLAESGETENASVQNIVTKEAAPKPINKVHNGYRPAN
                     VAFTAPTKINVTRETKNRNNELKEQLLKDIKP"
BASE COUNT          937 a          708 c          554 g         1238 t
ORIGIN      
        1 taagcgtcgt tgtcttcgtc cttgaatcaa tgcctgattc caaatcaacg tcatggccat
       61 gtacatctga cattgttgta cccctcgatc taggcctgta atagagtcaa tgtcaaaaaa
      121 gaccaactgt tgttggtcaa ggtgtcgaat cgtactatga ccatcaaaaa tcatgccata
      181 agtctcacat aaggattcca cgatagactc catttcttct ttccgattct ttttctcttg
      241 ggaagcccct ggtagttcca gttgtcctaa aaaggctaaa aattctttga acgtcggata
      301 agcttctgga tctttccctg tgacttgcgt atcagtattt gaacgcgaat ttgaggaagt
      361 aaaaccgcgt ggtactgttc catactcttc ataaaaacga ttcaagtagg tcttgaattc
      421 tgctttcatc gttcctttta gctgaggact cactaactgt acctgataga ctactttgtc
      481 taagtgcgtt tgataggacg ctgcttcatt gatcttcaaa tctttgactg aaccatcgtc
      541 atataaactg gatgcttcat catacgtccg tgtggcaaag atctctaaag gattgatcat
      601 cccgtcagat ccgtctaaac gcaccataat accgttatat tcctttaaga aaggaataaa
      661 gtcttttccc ttttcaaagc cccaaataaa gtctcctgca gctaaatggg cttccgcgat
      721 cattttaaga acggtcgatt taccagctcc catcattcct agaagcaagg tattggtaga
      781 taaacgtaca ctatttttat acgtggcatt ccagacaaat gggccgcctg tcatggtttc
      841 cccatattgt gtgcctcctg gatcttttag cgtttggtgg tggaacggga atcctccgcc
      901 aatgtttaac gatggaagtg attgcccttt gatatttcca aaccattcag cttgttcatc
      961 gaacatggta aacatcgatt gccaatctcg tttggtttta tgcagataag tcaccgcacg
     1021 ataatccatc ccttttagat tttcgatcag ttcctgcgcc cgttcatcca cttcttggat
     1081 cgtatttccg taaacatgta ctctcacttt gacttgttta gaaatttccc cattagaagt
     1141 caattttcgg gcatattccg ctagttccag gtattcttcc gcacttttat ttcggtcagt
     1201 cgcttttcgt tcattatctg atcgatcatt taattcatct aatgcgcggt tgatttgatc
     1261 aatcactttt tgcttttcat ctgtgctaac atctagtgtg gccactgtat gaggattgtt
     1321 catgagattg gccaaccaaa aaagagtagg attttttgtg taatgataaa ctgtcacaca
     1381 tcgtgaataa ccatttccat aggtcacata ttcttcatca aaattcaacc caccttgtgg
     1441 catcacttgt tttaagaaat ctaaatcata accttttgat tttaaaatct ctatttcacg
     1501 attaccaagt tgttttaatg gatcaatcac cttttgatta ctttgcgttg aaaaagctgt
     1561 ttttatcaca tctagcatga atcatttcct ccatcttttt tattcgtcat tcatgttgtt
     1621 cattcgataa agaatcttaa tcaattcttt tttgtagagt ggttttaacc ctaaaatgcc
     1681 actagatcgc attaactgac gatttctagt ttgtaaatcc ttgattgtct ttccttcaat
     1741 aacgaaaaag aagcttaagt caggacgttc ttgttctgcc cgttttaatt cctggatctc
     1801 ctctactaat ttcttttcat attttcttaa tcgctgtaga tttcttccta gtgactgttc
     1861 catacgattt ttatctaata actgccgctt ttgcacgatt tgttccgtta gatccgtctc
     1921 tgtggtcaaa ctaactaact taattgttgg cacatacgta cgcatgacgg tggtcaactg
     1981 attcattcgt tctagtttct cttgttcatt taatccctcc acgtcagtgg aaacgacacg
     2041 ataataacgc tgaaaatgat cttctctagt aattaagact ccctcttctg tacaggattt
     2101 atatggaaat aagtccaaga tagagcgctc ttctggtttt ccaaactgca aaatggattt
     2161 cttatcaact gaattttgtc ctttgactcg catttattca tcctccttat acgtaccatg
     2221 ataatttcgg ttaggatcta acgcatgata gtggttctta tccgtaaaga aaatagattc
     2281 gataatcgca aaaatttggc gttgaccagg gttattatag ggtcgccaaa caatcactaa
     2341 cgctatcgca agccataatc cataattcaa gagtgcaaaa aagagtggta agtggacaag
     2401 attattgact attttcgccc aaaaaaagca gccaccaagc gttaatagat ctaaaaagaa
     2461 aaaggcgaaa aacttccatt ccccactaaa tcttggagga tttttcatat gaatgtattt
     2521 atccataata taaccatacc ccttatattt tgtattttta gaaataaaaa acactgtgat
     2581 ttctcacagc gtttttctaa atattacaac tctaattcat ttcctaaatc acgagaacga
     2641 ttttttcctc gtcgtaattg ataattcaat tgacgatttt cttcttttaa ttcaacaatt
     2701 ttttgttcca gatttctttt cttttgaatt aaatcataat tttgtgcgcg taattcttca
     2761 ttttccaaat gaactcgttg catttcatcg tttaatcgat ttacattctc caatgattct
     2821 tgtatcgttt cttgcctaaa attaagtgag ccaagttgac gatctttttg ttgtctttgc
     2881 tctttcaatt ctgacgatat ttgctcaaca gaatgaaata tttccgttaa ttttactgtg
     2941 aatgtgggca tagcatcttt caaataagtg aatccttctg aaaggtgtac aataatgctt
     3001 tcggtatgtg ttttttgacc atctaaaata gactgatgat ctttttgtaa actatccgta
     3061 tctttaaatc ctttaatagt caccacaaat atcgttaaaa atgctcccag tgcagttata
     3121 aacgtagcta ttaaaatatc ctccacaatt ttctcctttc cattttaaac ttgttttata
     3181 aagaaaaagg cccttaaata ggccttttat ggtttgatat ccttcaatag ttgttctttc
     3241 aattcattgt tcctgttttt agtttctctt gtcacattta tttttgtcgg tgcagtaaat
     3301 gctacgtttg ctggtctgta tccattatga actttattga ttggcttagg tgcagcttct
     3361 tttgtcacaa tattttgaac ggacgcattc tctgtttcac cactttcagc taaattgtaa
     3421 gaaacagttg tcagatt
//
LOCUS       DACBZK010000152         3398 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.159, whole genome shotgun sequence.
ACCESSION   DACBZK010000152 DACBZK010000000
VERSION     DACBZK010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.159"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..276
                     /locus_tag="IVD66_002803"
     CDS             <1..276
                     /locus_tag="IVD66_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific recombinase"
                     /protein_id="HAP6146966.1"
                     /translation="ELIKLANKGQDYEHLADEIDELRDKRQLLLVEDASLSGENERIN
                     ELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEEHFVISFKSGIEMEI"
     gene            419..640
                     /locus_tag="IVD66_002804"
     CDS             419..640
                     /locus_tag="IVD66_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014315041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6146967.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGNEIKIGN"
     gene            656..1498
                     /locus_tag="IVD66_002805"
     CDS             656..1498
                     /locus_tag="IVD66_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146968.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            1561..3363
                     /locus_tag="IVD66_002806"
     CDS             1561..3363
                     /locus_tag="IVD66_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HAP6146969.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
BASE COUNT         1229 a          469 c          702 g          998 t
ORIGIN      
        1 gaactcatca agctggctaa taagggtcaa gattatgaac atctagcaga tgagattgat
       61 gagctgagag acaagcgaca gctcctttta gtagaagatg cctccctcag tggcgagaac
      121 gagcgaatca atgagctgat tgaatttatc cgcaagaaca aattccgtac cttagagtac
      181 gatgataagc ttgtaaggaa gataatccag agcgttacag tctatgaaga acacttcgtc
      241 atatccttca aatctggcat cgaaatggaa atatgaaaac cagaagtaaa tagcccatga
      301 ttctacagta gagtcgtggg ttttcttttg cttgctgatt ataataatat tttaataact
      361 attgttatta taaaccaaat gatttataat attcttagcg taaacttgga ggtgctgtat
      421 gactacggca gaaatgatta aagaactgtg tgagcaaatg aatataagtg tttccgaact
      481 tgctagacgt attggacaga ctccacagaa tttcaataag aaattacaac gagaaacggt
      541 aaccttagat gagttgaaag cgattgctga tgtgctaggt gtcaagtttg tgcaggcttt
      601 tatattgcct gatggcaatg aaataaagat aggtaattag gaggtgtaat ttgtattgaa
      661 aatcataaca ataaatgatg ttgagtatgc tgtatttgct gctaatgaag gtacttccaa
      721 accacaacct catatcatag aaacgaaatc tggtactatt ccagaaggaa aacaactgag
      781 tttattaaaa gaatatctta agcagaatga tatttcccca ataaaaggag caacaacata
      841 ttggtgcatt gacaaggttc ttaagcttga ttcaagtaaa gaaaaaacta taagtgaaac
      901 aatccataaa caaaaatact tatctttaac tgaagaaaat attgagaaac agcataagtt
      961 tgtaggtgca agctctaatt atgggaaaga aggtctaata atacatgatg ttttgaatgc
     1021 atttcctctt cataatgatt taaatactat tgcgatgaag attgcggtaa ttgatgtaac
     1081 aaattcaaca catctttctc aatataagag caggttgtct ctatatgatt tggctaaagt
     1141 aattctggag attccaaatt ttgatgatcg gttggcaaaa ggagatcctc agttgataaa
     1201 tattatcgca aggaacattg gtgcagttaa tatgttctca tttgcatcca agtactgtac
     1261 atatcataat gtggaagtgt gtgggagaga tgattactcc atctttgatg gtatcgttaa
     1321 aaatactctt ccacactata tccaaggact aactacgaat aagattgata cgtggcgaag
     1381 aagttttgat tacgaggcat ttaacgaatg tgttggaaaa ctacttgatg aaaataatat
     1441 acatattcct tttagaagaa gaaagttaga tcacttcttg tggtatgcga ataggtagaa
     1501 tataagaaaa aggcatcgta aaagtgattc tggataaaat taatggggga ggaaataata
     1561 gtgggattat ttgattttct aaagaaaaaa caaggaaagg ttagtaaaca cgttgattat
     1621 caactggctt ctagtctatt tcgtactggt aaagtttttg ctgaaaaatt ggaagtggac
     1681 atatcaaatg tagatgagtt tcgtaaaact tttatcgctt ttgatgtgga aacaactggc
     1741 ctaaattctt cttcagatag aattgtagag attggtgcgg tgctatttaa agaaggagtt
     1801 ccaattcaat cattcggaac tcttgtcaat ccaaaagtta gaattgcagc ctcagcttcg
     1861 gcaataaata atataactaa tgaaatgcta aactctgctc caaatgagca ggaagtttac
     1921 ccccagttgg tagaattttt aggagatgca ctagatggaa aaatcactat gtgtgcacac
     1981 aatgcaagtt tcgattttgg atttttaagt aacacatttt ctagacttgg gtatgatgct
     2041 aaaattaagt atgttgatac tctgagtctc tctagaaaac atataaaagg cattgtaaat
     2101 cataagcaag agactgtagc ggaatatttc ggattaataa atgacactgc ccatagagcg
     2161 gaatcagatg cagatatatg cggaaagatt ttttggggtg ttttagatat tattgaggag
     2221 tcgttggaag aacaaaaaaa gcaaatagaa aagatgactc cagacataaa agaacttgaa
     2281 gcttgtgctt ttattcaaga tattattgag aaaaaaggat gcgacaccag ttggatcagg
     2341 tatcgaaaaa acagtaataa ttatgtcgat gtaacttgtc tatatacatt cttaaagttt
     2401 aagtttgcta agaagggaaa ttacatcatt attagaaaag atgctacaaa tggaattgat
     2461 ttacctatag aaccttgtac tgtaagtgaa ggcggtacaa caaatgtgcg agtctatttt
     2521 cgtagcccct ttgacttaac gcctctttca aattatattt tcagtgctta tagcgattgt
     2581 tataattcta tgaatgaata tatgagtgtt agtaattaca ctaaaaaaga agcagagcaa
     2641 agccttagta tgctgaaatc tatttcaaaa tcagcgatga aagagttatt attcgatgca
     2701 aaaaatcgtg gatatgatga gactgaagtt aacctaaata ttgaaaaagt gatatctaga
     2761 gaagatgtaa ttattaacgg gttgcataat cgagtttcat taaacaagat acgaaatata
     2821 gggaattggg agaaaggatt tgatgcaggt tatccatatt gggaacgtgg agaaactgct
     2881 aggaaaaatg gcaaagtaga tgaagctatt gcactttttg ataaagctcg atataacggc
     2941 tatgatgctc ctgcgctata tgattcttat gctaaagctt atcgaaaaat taaggattac
     3001 gataatgaaa ttctcattct tgatgaagga attatgcgta aaacacggca cgatgttggt
     3061 actttagagg ctcgtaggga taaggcaatt aagctattat ttgctaaaca agaggcagag
     3121 cggatagcta aggaaaaatc tgattttcta aaagcgaaca aaaaagagga tgcgattagt
     3181 gagcctagca agaagcgtgg aagacagatt attcaaatga ctgatgatgg aacaataata
     3241 aaagaattcg atactatagc ttctgctgta aaagaagttg gcgttaactc aaaaagtatt
     3301 agggatgctg caaatggagt tcaaaaacat gctggaggat actactggaa atacaaagat
     3361 tagcagataa tctaagataa cctaggatct tcttaata
//
LOCUS       DACBZK010000153         3354 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.160, whole genome shotgun sequence.
ACCESSION   DACBZK010000153 DACBZK010000000
VERSION     DACBZK010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3354
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.160"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            39..590
                     /locus_tag="IVD66_002807"
     CDS             39..590
                     /locus_tag="IVD66_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HAP6146970.1"
                     /translation="MKRLEASTSNFNNKLDVFEEKTKHARLNFETTAKHYIKRLDEDN
                     LKLDFQQAIQDELSDTKDEIREVTKQAREETKEYKEILESKIKDHNKVVDKSNTALKV
                     MTKGVTNIFFVLIIFVLVMLVTGPIGHFFGIEHLYSFINGFIDDHESAWRYLMLILYA
                     VPYVFFAIILWLIALFFRVFNDL"
     gene            1266..1532
                     /locus_tag="IVD66_002808"
     CDS             1266..1532
                     /locus_tag="IVD66_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146971.1"
                     /translation="MAKITKNEQENLVENYTKKPAYSNSRLDAHFVCTSNPKLSFDAM
                     TIVGNLNKNSAKKLSDFMSLDPQIRLWDILQTKFKAKALQDPLC"
     gene            1590..2102
                     /locus_tag="IVD66_002809"
     CDS             1590..2102
                     /locus_tag="IVD66_002809"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003321317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP6146972.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLC
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            2099..3136
                     /locus_tag="IVD66_002810"
     CDS             2099..3136
                     /locus_tag="IVD66_002810"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP6146973.1"
                     /translation="MISSSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
BASE COUNT         1233 a          572 c          664 g          885 t
ORIGIN      
        1 agagcgagca agacaggaac gagagaacaa acatactcat gaaaagacta gaggcttcga
       61 cctcgaactt taataataag ttagatgttt ttgaagaaaa gactaagcat gcaagattaa
      121 actttgaaac aactgcaaag cactatatta aacgacttga tgaagataat ttgaaattag
      181 attttcaaca agctattcaa gatgaattaa gcgatactaa agacgaaata cgtgaagtga
      241 cgaaacaagc gagagaagaa acaaaagagt ataaagaaat cttagaaagt aaaataaaag
      301 accataacaa agtggttgat aaatcgaata cagcgctaaa agtgatgaca aaaggcgtta
      361 caaatatatt ttttgtgcta attatttttg tacttgtaat gcttgtgaca ggtccgatag
      421 gtcatttctt tggtattgaa catttatata gctttattaa tggttttatt gatgaccacg
      481 aaagtgcatg gcgatatttg atgttgatac tttatgcagt accctatgta ttcttcgcta
      541 tcattctgtg gctcatagca ttgtttttta gagtatttaa tgacctttag gtagatttat
      601 atataaaaag ggctaaatac gcaaaatacc cccttaaaat gcaaaataaa tgcaaataag
      661 ggggtaactc cttatgaaaa aacaactaat agtattataa cacgttttta tgccgagaaa
      721 acttattggt tggaatgggc tatgtgttag ctaacttgtt agcgagttgg ttggacttga
      781 attgggatta atcccaagaa agtaccaact caacaacaca taaagccctg taggttccga
      841 ccaataagga aattggaata aagcaacgaa aggagttgag taaaatgagt gagaaaacga
      901 agaaaatcat tcgagtatca ttagcttttt cacaagtagt agtgcaatca ttgatagttt
      961 attatactta ccagcaatat aaattatcta aagagaatta agttttgatt atgtaataag
     1021 ttttggtact aaaaaagact tgatctaatt agaccaagtc ttttgttagt gttatattaa
     1081 taacaaaata aaaataagaa gtcgctcact ccccgaccaa agtttgtgag caaaataaac
     1141 agtcgatgtt tgtttcttaa ttgtatatct tgatattaaa cgatttaaga ttattcttca
     1201 agatatatat tcgcaaatgt aattggaaaa gcgacttctt aaacaaaatt aaggagtcgc
     1261 tttttatggc aaaaataacg aaaaatgagc aagaaaattt ggtggaaaat tacacaaaaa
     1321 aaccggcgta ctctaatagc cggttagacg cacatttcgt gtgcacttct aatccgaaat
     1381 tgagctttga cgctatgacg atagtcggaa accttaataa aaacagcgct aaaaagctat
     1441 ccgattttat gagtttagat ccacaaatta gactttggga tatacttcaa acaaaattta
     1501 aagctaaagc actacaagac cccctatgtt aggctagttg tcgtatagga taataagtta
     1561 taataaagac tatacggagg atgattacca tgacaaataa aaacaatgaa cgttactcta
     1621 ccgaactgaa agcgacagcc atcaagaaaa tgatgccacc cgaaaatagg gggattcgcc
     1681 aattaagtca aactttgggc attccagaag cgactctttg ttcttggcgt aaaaaagcta
     1741 gaattcaagg gaatactaca cccggaacga aaaaaaatgt cgaaaaatgg tcaagtgaag
     1801 ataaattttt aattgtgatg gaatcattct caatgaacca agtagaactt gcggaatatt
     1861 gccgaaagaa gggcttattt aaagaacaaa ttgaggcttg gaagaaaacg tgcttatctg
     1921 cgaatgaaca ggaagaaaat cgaacgagag aacttgcaac tgaactaaaa gaagagaaaa
     1981 aacaagcgcg tcaattagag aaagaattac gtcataagga aaaagcatta gcggaagccg
     2041 ctgctctctt attactaaga aaaaaagcac acgcgatttg gggggaccaa gaggaagaat
     2101 gatttcatct tcagatcgca aacaagctgt tgaacttatt caagaagcca atcgcaatgg
     2161 ggcccgtctc acctatgcct gtaatgagct gaatattagc gttcgaacct acgaacgatg
     2221 gacgcgtgaa ggtacgatag cgcatgatca acgccctttg gcgaaacgtc ctgtacccaa
     2281 aaataaactg acggatcaag aacgcgaaaa aataatagaa accgtttcaa aaaaagaatt
     2341 tatgaatttg ccacctagcc aaattgtacc aaaacttgcg gattgctcga tttatattgc
     2401 atcagagtct agcttctatc gtgtattgcg agaaaaaaat atgcaacatc accgtggccg
     2461 aagtcaagtt tcacaaaaac gcataccgcc aagtcacctt gcgacgaagc caaatgaagt
     2521 ttggacttgg gatattactt ggctaaaagg tccaataaaa ggactctttt accggttata
     2581 tctcatcatt gatttattta gccgtaaaat ggtaggctgg gagatttggg aatcagaaga
     2641 agctcgtcat gccgaaaaac ttattaaaca gacggtgctt aaggaacgta tccaaggaca
     2701 gccgttggtt ttacactccg ataatggcag ccctatgaaa gccgcgactt ttcaagtctt
     2761 actcgaaaaa ttaggaattc aaagttctta ttcaagacca cgagtgagta atgacaatcc
     2821 ttattcggaa gcggctttcc gaacgttaaa atatcgacca gaatatccca ataacggctt
     2881 taaaacaata gatgatgctc gaaaatggac gaaagagttt gtcgattggt ataacgattc
     2941 tcatttgcat agtgggattc aatttgtgtc tcctgcagcg tgtcatgaag gacgacatct
     3001 cgctatttta gagaaacgaa agcaggttta cgaggacgct aaaaagcgcc atcctgaacg
     3061 ctggtcaaaa ggtgttcgaa attggactcc acatcaatcg gtggcgttga atcctttaaa
     3121 agaaacagaa agttaacagg agcataatct ttcaagatta tcaaataacc ctcgtcaccc
     3181 aataggggaa aaagttattc ttcccctatt ggataacgag gccaaccgac catagggagg
     3241 ttctgctttt tgataggtgg aaaataaaaa tacgacaact atattgacaa acaccgacca
     3301 tcgtccagta aagagacgca ataaattcta tcgaagttta cgcactgcct ctac
//
LOCUS       DACBZK010000154         3283 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.161, whole genome shotgun sequence.
ACCESSION   DACBZK010000154 DACBZK010000000
VERSION     DACBZK010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3283
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.161"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            3..587
                     /locus_tag="IVD66_002811"
     CDS             3..587
                     /locus_tag="IVD66_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP6146974.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(664..1839)
                     /locus_tag="IVD66_002812"
     CDS             complement(664..1839)
                     /locus_tag="IVD66_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP6146975.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            1921..2301
                     /locus_tag="IVD66_002813"
     CDS             1921..2301
                     /locus_tag="IVD66_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HAP6146976.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            2375..2737
                     /locus_tag="IVD66_002814"
     CDS             2375..2737
                     /locus_tag="IVD66_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146977.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1115 a          538 c          622 g         1008 t
ORIGIN      
        1 atatggcatt cccacaacta gatttaaaaa gtgaaaaagg accaaaagct gttatcaaaa
       61 caaaccgtgg tgacattact gttcaattat tccctgaact agcaccgaag acggttcaaa
      121 atttcattga actttccaaa aaaggttatt atgatggcgt gatttttcac cgcgttattc
      181 ctgatttcat gatccaaggc ggcgatccaa ctggaacagg aatgggtggc gaaagtattt
      241 atggcgaaag ttttgaagat gaattcagtc gtgaactgtt caaccttcgc ggagctttat
      301 ctatggcaaa ttcaggtcca aacacaaacg gaagccaatt ctttattgta aataacacaa
      361 atgtgccagc taatatgctt ggacaactag aaggtgctgg attcccatca gaaatcattg
      421 aagcgtataa aggtggcgga actccttggc tagatttccg acatacagtc tttggacatg
      481 tactagaagg gatggacaca gtagatgaaa tcgcaaatgt acaacgtggt ccacaagacc
      541 gacctgtaca tgatgtagtg attgaaacaa ttgaaatttc agaatagttt ggtatggtac
      601 ggagtaatta tgaaaaagga cgaaacctag taaggtctcg tccttttatt ttgaataaat
      661 gatttaatcg attgtctcta aagcatactt gattcgatta agtccttcca gtaaagtttc
      721 ttctggacaa gcaatattca agcgcatatg cccatgaccg gaaggaccaa acgtgatgcc
      781 aggatttaat acgacttttc ctttccgaac aagagtgttc tccaattctt ggtcgtctga
      841 aatataggcg gtaaaatcta accacattaa gtaagttcct tcagggttca ttattctcac
      901 tttcggaaga tactgttcaa aaaactgatt aactgtttga acattttttt ctagataagg
      961 aatcagttgg cttaaccatt ctccacccgt ctcataagcc gcttgggttc caatcagtcc
     1021 aaaagtgttg atttcgtgct gttggttcat cactaaatgt ttttcaaaat cagctttcat
     1081 ctctggattt ttgataaata ccattgaatt tttgattgca gctagattga aagtcttggt
     1141 tgcggaagta aaagcaacta gtagatcatc taaattagga tcaatcgtta gcatggaagt
     1201 aaatgtatga tcgaataaag ttaaatcttg atggatctcg tcactaaaca gaatcacttg
     1261 atgttttaaa cacaattcgc ttaactgttt caattcttct ttgctccaaa cacgccctcc
     1321 aggattgtga ggattgcata aaatcattgc ttttacattg ttttcttcga tttttttctc
     1381 catgtcagac aagtccatga tgaaatgatt atttttttct agcaaagagc ttcgaacgat
     1441 gtgacgttga tttgtttcta taatagagga aaatggagga taaactgggt catgaatcaa
     1501 aatagaatcg cctggttttg taaaagtttg tactgctgca gctaaactgg ttaacacacc
     1561 acttgtaaaa acgatatttt ctttcgtcaa ctccacagca tggtgttggc gttcccaatg
     1621 aatgatagcc tgatatagtt tatcagacag agtggcataa ccaaagattc catgtttgat
     1681 gtattcacta aacgctttag ctaccccacc gggagacaag aagtccatat ctgctaccca
     1741 caaaggaagt aagtcatcca tttgatatgt ctcagcaatt gcgtcccatt ttacactttc
     1801 tgtatctttt cttgaaatct gtttatcaaa ttcgatcatc ttaagacctc cagtcatttt
     1861 cgtcgcttct ttttttgagc tatttacagt ataatgataa atgcgaagag agggaagtag
     1921 atgacttata aaattggaca aataattgaa ggaaaagtga cagggataca gccttatggc
     1981 gcattcgttt ctcttgataa cgagacgcaa ggacttattc atgtttcaga agtacaatcc
     2041 ggttatacga aaaatatcca ttcattgtta aaagtcggac agccagtaac agttcagatc
     2101 atcgacattg atgaatattc caaaaaaatc agtttatctt taagaacgtt agaaaaaaca
     2161 aatccagctg ttccatatcg cagaaaaagg tatttcacga ataaaaatcg taagatcgga
     2221 tttaccacta ttgcggagca gttacctatt tggatagaag aagcattatc tgaactagaa
     2281 cggaaagaaa ataagaaata aaaagtgtat tttttctgaa aatgtgctag aatttttatg
     2341 taagccatag aacaagttga tcgaggtgga aattttggca agcaaaagag ttgctggtac
     2401 aattatgttg catttggagg atggtactaa aaaatttttg gtccattcaa ttgatgacaa
     2461 gttggaattt gcgttagcgg aactttctga aggaaagact ggtttagcga atatacttaa
     2521 tttcttaaaa gaaatagttc atatcgatgt tagcaagatt agtttgatgg aattgacaaa
     2581 tacacatatt aaagaggaaa atgttccgtt gtttgtcttt gaaactgaac aaaagaatca
     2641 aagagaagaa ttaggcgaag gatatatttg ggaagaacca ggtcaaatgc gctctgttct
     2701 tggaacttac gaagtagagg gagtgccttt cttctaaaat acagattaag cgaacaaaga
     2761 agtttgaatt tttttcaaac ttcttttttt attgtttggt ccaaaaaata caatgaaatg
     2821 ttctgctaaa gatagttttt tagtgcattt tattttcaaa atatgttgaa aacggttgta
     2881 taacgaataa taataattga tcgaaaaatc atttcacaaa gtaatgctta atttatagtt
     2941 gaccaaggaa gaaatacatg ataaatttaa cagcgttgat tctgaagtgg atgttatatc
     3001 acatttctaa aaaatttaaa aaatagttat tgacatgtta ctaacgacat gataagataa
     3061 ctgagtcgtt aaaaaagaac cacttgcgaa gcttgattct atcgaaaaaa acttcaaaaa
     3121 agttcttgac aaataacaaa cgataagtta tgataaatga gttgctgaaa gatttcgaaa
     3181 aacgaaatcg aaaaaaactt ttaaaaaaga gttgacaatc gcttgtctct ctgatatgat
     3241 ataaaagttg ctacggcagc caaaaacgaa tcgggaaaca ctc
//
LOCUS       DACBZK010000155         3279 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.162, whole genome shotgun sequence.
ACCESSION   DACBZK010000155 DACBZK010000000
VERSION     DACBZK010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.162"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(366..1484)
                     /locus_tag="IVD66_002815"
     CDS             complement(366..1484)
                     /locus_tag="IVD66_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146978.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1955..3262
                     /locus_tag="IVD66_002816"
     CDS             1955..3262
                     /locus_tag="IVD66_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAP6146979.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
BASE COUNT         1032 a          679 c          590 g          978 t
ORIGIN      
        1 tttaaacggt gttccagaag tagcttcttc ggaaataagc cgaaatttca caaaaatttg
       61 agaaataatt tttgtcaatc tcttcttatt tcttgaagct gaccacttct gtcacaacct
      121 cttccttaaa cggtgttcaa aagcttgcat ctgcggtaat aagcccacca aacaaaaaat
      181 atgaagagct atttttgctt gctgttctta ttacttgatg cagaacagct ttttcacaac
      241 ctctcataca cggtgtttaa tcagctgacc ttcggtatta gctcaaaaaa cggaaaaata
      301 tgtgaaacta tttttccgtt tgtttctcta atactcaggt caaaacactg atttcacaac
      361 ctcttttaat aacgaagaat cgctgtcaga ctcttttcat ctggcgcatc tttttgatcc
      421 aaaataaaca ctttcccgcc attaatgatc acatcatctg ctaatgcatt caacacttga
      481 cgccgatcat attctgtttc aggatcttca ccgaaaccat cagctaagtt tgacgtagcg
      541 ataaataaat gtgacacttt tccttctttc gcagctggaa cgatatcaac taactgatcg
      601 atgaatttct tatctaagag tttattgtat tcttttgatt cttgagctgc gagttcactt
      661 gacagcttct tcgccccttc ttcgatatct ctaaaggata gctgcgcagg agaagcagaa
      721 atcgcaacgt ctgcacaata atagggattt ttagcaattt ttttgaacat cgtctgattt
      781 tctggtaatg caaataaata aatcggccat tgttcaggat tttcgaaaga atccttcaag
      841 tacgtatcaa cagcttggta atagttgacc caatcgatct ctacttcttc atcttttgga
      901 tttacgccat ggaaagttac tccatctcgg gctccgcctc ctccattaga agagaagttc
      961 aaaccgccac ctgtcagttc agatcccaat gcagtaacga catcaaccgg tgccccttct
     1021 ggtagagata cttcttttac ttgtttgttg ctgacctcat acaatttcat ggagtcgcgg
     1081 ttcaatccca ataaataata agaatagttg aactgcccat ttttgataat agccagtaaa
     1141 taaggaagat cacttacata gtattgatcg tctaccggga tactcaaacg atggatatag
     1201 gtctggtcag cagttataat gaccgctaca ctcgtagttg cactacgcca aaacgaagga
     1261 tctcctaaca aattttcaat tttttcttgg aacggggacc agtcatgttc ggaatatttt
     1321 ttctcaaaac gtttctttgc ttctttcgca aaatttttga atttgatctg atctttttcc
     1381 acatcttgat gggcgacatg cgtattcagc atgatcgtga cgaatggtcc tttagcgcct
     1441 tctgaagtca attgtgtcaa taattcttta tccttttttg ccataaacgt acccctccta
     1501 aaaaaatcat tcctttgttt ctatctaaag tctaccacaa cactattttt ccatacaata
     1561 aaacgtatct aaaaaaataa aacggtttct acggttttaa atttagctat ttttttaagt
     1621 tatcttcata atttcctcaa ttatttagcc ccagtcttca actattcttc atgaaatgct
     1681 gataaactaa gaaaaagaat aaaagaggtg gatcttatgc atttgattat gattttcagt
     1741 ttattaagta ttatcagttt atttgctttc agcgcttccc gcttattaga tgcggaaaca
     1801 cagcctattc ctgtaaaagt acgtaaaaac gaccgctaaa cttccataac gcgcgttctt
     1861 atcctaaagt tttttcagaa acattgaaac tctctcccct ctctgataaa attttaattt
     1921 gtagcgaaac aaattaatta caaggagatc ggatatgtcc ataaaaaaaa cacgtctagt
     1981 cctattattg gctagtctca ttctttgcct tgcttctttt ctaccagctg ttgctgtgca
     2041 agctgaagat acgttcaaag taaatgcaaa agcagctttt gctgtagatg cgcaaagcgg
     2101 taagattctt tatgatcaag atggagaaaa aaccatgggg atcgcttcaa tcacaaaaat
     2161 catcggtctt tacatcgtcc ttgatcaagt aaaagaagga aaactgtcat ggggtgataa
     2221 agtttcgatt tcagattatg cagaaaattt gagtatcacc ccagatttat cgaatgttcc
     2281 tttgcataaa gaaaacacct acactgtcaa agaattattc gactctgcaa tcatccagtc
     2341 agccaatgct tcaatggtgg ccttggcaga aaaaatctct ggcagcgaag ctaaattcac
     2401 tgaacgaatg aaagaacaat tgaaagattg gggaatcaaa gatgcaacaa tcgttaatgc
     2461 atcaggattg aacaactctt atcttggcga aaaccgacca gaaggcactg gagaaaacga
     2521 cgaaaatcaa atgtctgctc aagatgtggc catcgttgcc cgccatttga tcttggattt
     2581 cccagaaata ctggatgtat caagtactac gacccaaatg tttggcgaaa atacgcaatc
     2641 accagtggaa atggtcaact ggaactggat gctcccagga ttcgttaatt acaaggaagg
     2701 cgtggacgga ttaaaaactg gtacgactga gcttgcaggt gcttgtttcg ttggtacgat
     2761 cactaaaaac gatcaacgga tcatcactgt cgtattgaat gcggacggcc atgcggaaaa
     2821 cccgagtgcc cgcttcaatg aaacagaccg tttgatggac tactgctatg acaattggtc
     2881 agaaaaagag ctcggaaaag ctaacgcaag tattcctagt ctaaaaacca ttgatgtaaa
     2941 agacggaaaa gaatcaacag ttcctgttgt gcttaaaagc cctgtaaaag tatgggtacg
     3001 aaacgatatg gatactggca aattaacgat cacgccaaca cttgacaaga agcaagtcac
     3061 tgacaatgag atccaagcac ctatggataa aggtacaaaa atcggtaccg ctacgatcac
     3121 cttggcagac gataaattag gctatttaga agacaacaat gcaccatcaa cagagatcat
     3181 tacggataaa acagtggaaa aagcgaatat attcgtgatt ggctggcgac gcgtcgcaga
     3241 atttttcggc aacttgtttt aattgaacaa taagaaaaa
//
LOCUS       DACBZK010000156         3271 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.163, whole genome shotgun sequence.
ACCESSION   DACBZK010000156 DACBZK010000000
VERSION     DACBZK010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.163"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(144..2201)
                     /locus_tag="IVD66_002817"
     CDS             complement(144..2201)
                     /locus_tag="IVD66_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HAP6146980.1"
                     /translation="MKLLNPKTVIAIGTFAATVALAGSADAASTNVMYRLYNPNNHEH
                     FYTSSTKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVTSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNTLDSAYKGLKKKPAPTVNKTELQALYNQVKSTAKGDFTEGSWNNFQTAL
                     SNAKKVLDDSKASQTQVNNAKNSLDSAFKGLQHKPKPSEYAVTVRHMNRQTGTLLKEE
                     HVSVKAGTSYTAKARTDLTNFEAPQYQVNGNETQTQTINTNTTFTFYYDEVFLVEVKA
                     RPNKVSDTDPNIQELYNYSKSYPVVYGQSITIEAPMFTNFVLDPRESSSNTVTLNNVT
                     SNQGINFAYTHQYNVTVNHINVDTNAVLSTETQTVYEGDSFSTSWKNMTDQNYFLCRN
                     DDSSVTVDKNGQRVINNVDQNRTITFKYKNISLSDLNNYVRQKELAWLNSYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENINSFYLYVD
                     EILSDTGAVNAMVMWKDSAAHNANLLYNNQSIVGLSHAYEVSADGSLSSDNVFISANP
                     IFK"
     gene            complement(2346..2537)
                     /locus_tag="IVD66_002818"
     CDS             complement(2346..2537)
                     /locus_tag="IVD66_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146981.1"
                     /translation="MYADKEKIEWLLFETGKTAYEISKHSSVAESTIADLIKKKSAIE
                     KMRFDNAAKLTKYAESISS"
     gene            2725..3180
                     /locus_tag="IVD66_002819"
     CDS             2725..3180
                     /locus_tag="IVD66_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146982.1"
                     /translation="MKKLIMVFTSLIAMIVILGGCGSEKNKQDSQDNGVLKPGTVWKE
                     EVGGLVHNLKIIDDTTWEYSESVWHPEQVQITVEKLKDYKGLERYKVIDSGGVDLFIG
                     KTALIVPYNKDGLETFKFIPTNEKEHRDKSEILKEYSTKSGYKLQKTSE"
     gene            3177..>3271
                     /locus_tag="IVD66_002820"
     CDS             3177..>3271
                     /locus_tag="IVD66_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146983.1"
                     /translation="MIASLFICPEGGIAVAKAKTPFEKAASKILER"
BASE COUNT          975 a          541 c          647 g         1108 t
ORIGIN      
        1 gttattgttc ctaaaacagg ttctacacat ttagtaacga ttttagcggt cagcttacta
       61 ttacttgtgt tagcaacttt tggctacgca gttctgaagt tcaattaaac aaaaaaacaa
      121 ggctgaaaat cagccttgtt tttctatttg aaaatgggat tggcactaat aaatacgttg
      181 tctgaagaaa gtgatccgtc tgcagaaact tcataagcat gggataaacc aacgatactt
      241 tgattgttgt aaagtaagtt tgcgttatga gcagcgctat ctttccacat aaccatagca
      301 tttactgctc ctgtatctga aaggatctcg tcaacgtaaa ggtagaaact attgatattt
      361 tctcctttag caccgtagca gcctaagctt tctaagagat cttggaaagt accgccgcca
      421 ggtcggtaat gactgaagct tacttgtaat tcttttgcac gaatatctgc agcttgttga
      481 acgatatcat tgaattgcat tggggcaacg ccattttgtt gacggtagct atttaaccaa
      541 gcaagttctt tttgacgcac atagttgttt aaatcactta gtgagatatt tttgtatttg
      601 aaagtgatcg ttcgattttg gtcaacatta ttgattacac gttgtccatt tttatcaacg
      661 gtaacagatg aatcgtcatt tctacacaag aagtagtttt gatcggtcat atttttccaa
      721 gaagtagaga aactatctcc ctcgtaaacc gtttgtgttt cagtagataa aacagcgttt
      781 gtgtcaacgt ttatatggtt cacagtgacg ttgtattgat gagtataggc aaaattgatt
      841 ccttgattac ttgtaacgtt gtttaaagtc acagtgttgc tagagctttc tctaggatca
      901 agaacaaaat tagtgaacat aggtgcttca attgtgatgc tttgtccata aacgacggga
      961 taactcttac tgtaattata gagttcttgg atatttggat cagtatccga gactttattt
     1021 ggacgagctt tcacttcaac tagaaagact tcatcatagt aaaaagtaaa tgtggtattt
     1081 gtgttaatcg tttgtgtttg tgtttcattc ccatttactt gatactgtgg tgcttcaaag
     1141 ttagtcaagt cggttctagc ttttgcagtg taacttgtac cagcttttac tgagacatgt
     1201 tcttctttta gcagcgttcc agtttgtcga ttcatatgac ggacagttac cgcatattct
     1261 gaaggtttag gtttgtgttg taacccttta aatgcagaat caagactatt tttagcatta
     1321 tttacttggg tttgagaagc tttagaatcg tctagtactt ttttagcatt ggataaagca
     1381 gtctgaaaat tattccaaga tccttctgta aaatctcctt tagcagttga ttttacttgg
     1441 ttgtacaagg cttgtaattc cgttttgttc acagtaggag ctggtttttt ctttaatccc
     1501 ttgtaagcag aatctaatgt gtttttggca ctatccactt gtttttgagt cgcttttgag
     1561 tcatttaaca cttttttagc attgtttaaa gcggtttgga atgcgttcca ggtattgtcg
     1621 gtatagtcac cttttttagt tcccttaacg ctcgtataaa gagcttctaa agctgattta
     1681 ttcactttgg gtttagaggt gtcagcacca taccaaccaa taccttcgta tttccagcca
     1741 tagtctttgg ttaaccattg tacttctttc caacttgcag tgtagtgatg cgaaccagag
     1801 gtaacacctg gaaggaaaag gcggtagatc ggtttattat ttttttcggc agaacgccag
     1861 gcaggccctt cataagtcca accgtaattt ttggtcaacc atttcacttc atcccaacta
     1921 gctgtgtaat ggtgatcacg aaggccttta ttgtataaac gatagacaag gtggccaccg
     1981 ctagtcggtg cttcccaagc ggggccttca taattacccc acttaatttt cactaggtga
     2041 tcacgttctt ttgtgctaga ggtgtaaaaa tgttcatggt tatttggatt ataaaggcga
     2101 tacatgacgt tagttgaagc agcgtcagca gatccagcaa gagcaactgt ggcagcaaat
     2161 gttccaatag ctataacagt ttttgggttt aataatttca tgttttcaac tccctattaa
     2221 atgattaaat attttgttta cattcataat ataccacggt ataccgaggt agtcaacggt
     2281 ataccgtgga aattttgaaa taaaaaagcc gccctatgaa gagtgtaagg atggctgttt
     2341 atatgctatg aagaaatgga ttcggcgtat ttggttagtt tggcagcatt atcaaatcgc
     2401 attttttcaa tcgcactttt tttctttatt aaatccgcaa ttgttgattc tgcgactgaa
     2461 gaatgtttgc taatttcata tgctgtcttg ccagtttcaa atagtaacca ttcgattttc
     2521 tctttatcag cgtacattgc aatgctccct cttgattttt tctttattat agctcttttt
     2581 tgtaataaat cacaatatca agaggaaaag tttctataga aaggtgggaa attatgagta
     2641 tccgttcccc gtgtatcaaa atgaggtttg ttgctacttt cgttatttaa tatactaaaa
     2701 taaaacaacg aaagaaggaa tagaatgaaa aagttaataa tggtatttac ttcgttgatt
     2761 gccatgattg ttattttagg tggatgtggt agtgaaaaaa ataagcaaga tagtcaagat
     2821 aatggcgtgt taaaaccagg aacagtgtgg aaagaagaag taggcggact tgttcataat
     2881 ttaaaaatta tagatgatac aacatgggaa tattccgaaa gtgtttggca tcctgaacaa
     2941 gtacaaataa cagttgagaa gctaaaagac tataaaggat tagaaagata taaggtaatc
     3001 gattcaggtg gagtagattt attcataggt aaaacagcct taatagttcc ctataacaaa
     3061 gacggtttag aaacgtttaa atttattcca acaaacgaaa aagaacatcg agataaaagt
     3121 gaaatattaa aagaatacag tactaaatct ggatacaagt tacaaaagac tagcgagtga
     3181 ttgctagtct ttttatttgt cctgaaggag gaatcgcagt ggcaaaagct aaaacgccat
     3241 ttgaaaaagc cgcgtctaaa atcttagaac g
//
LOCUS       DACBZK010000157         3220 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.164, whole genome shotgun sequence.
ACCESSION   DACBZK010000157 DACBZK010000000
VERSION     DACBZK010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.164"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(62..280)
                     /locus_tag="IVD66_002821"
                     /pseudo
     CDS             complement(62..280)
                     /locus_tag="IVD66_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(546..740)
                     /locus_tag="IVD66_002822"
     CDS             complement(546..740)
                     /locus_tag="IVD66_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146984.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            2092..3132
                     /locus_tag="IVD66_002823"
     CDS             2092..3132
                     /locus_tag="IVD66_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepA"
                     /protein_id="HAP6146985.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
BASE COUNT         1193 a          449 c          462 g         1116 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattgta ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt attacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa taaagtagtt tataattagc aagtatatat
     1321 atttaaaaat ttaagattaa tttttttatg acttgtacaa atttatctga tattctctta
     1381 ttaagaacta cctaatttgg gtagttctta ttttttacat tttaagtagt atttaattgc
     1441 aatttggtag tattttttta ttatcttatt cttagaacgg tagtacttaa tataaatata
     1501 ggtagtatct aatttaagta ttaatggtag tatctaaatt aacaggtagt atgtaactac
     1561 tttaaagtaa tttttttcag attaacacag tagtatctta ttaaataagt taattttaat
     1621 ggtagtacat aattattata tatatctgac attggtagta cttattgtat tttttagtag
     1681 tatataatct attgttttct agcctaaagc cttgtcttat aagaataata taatatatac
     1741 tactgaaata aggtagtata tattactagt aatggtagta tgttttatat gcataaggta
     1801 gttcttaatt tattttttgt tttgacactg gtagtactta attatcttta attttaaaac
     1861 taaattttat tcatacgttt ttctggtagt atttaattat aaataatatt tatttaaagt
     1921 agttcttaat gactttaaag gtagtacata attcatttta tttctgattt taggtagtat
     1981 ttaattaaaa aacagtttta atgcgtttgc attttttatt tatctttgct attttcgaaa
     2041 agagtaggta attttacata aataaaacaa cgtgaaagta gaggatctac aatgactgat
     2101 tttaaatttt ttaaggcgga tagagtttac aacgaattat tttatcaatt tccaaaagtc
     2161 tttattgttt ctgacgaata caaaaaaatg aaagattcaa ctaagattgc ctatatgctt
     2221 ttaaaagcaa gattagagat cgcaatcagc aaacggcaaa tcgatgaaga aggtaatgtt
     2281 tattttactt atacgacaaa tgaactatgt agagtattaa actgccaaaa acaaaaagcg
     2341 atagcaatca aaaaagagtt ggaatccttt ggtttattat tacaaaagca gatgggattt
     2401 aacaaacagt tagggaaaaa taatcctaat agactatatc tagcagaatt aaaagtctca
     2461 gaaaatgata tctacttact cgaaaaattt gatagagaga atagggaaaa cgttgataaa
     2521 tcagagggta tgaaaatcat acccaccctc gacgaaaaat cagacgctga atcccttggg
     2581 gctcaagagg gtatgaaaat cataccgtgc caaaacgttg ataaatcaga gggtatgaaa
     2641 atcataccag aacttaataa taatatatta gacactaata gacacaatat agacactgaa
     2701 aaagaccgcc tacaagatca attgttgtta gacaattttg agacaattat gacaaacgac
     2761 agcattgcta cgtttgtccc tgaacgagta ttaaatttga taaaaacatt ttcttcaagt
     2821 tacagtgaag ctcaaaaaac cgtccagact attcataatg caaagaaaaa agctgaaata
     2881 gaaagtgata tttcgatagt ttttgaagaa ctcgatagtt attatgtcaa tgcagaacaa
     2941 gaattataca cgacactgtt aaaagcctat caaaaattaa aaaccgaaaa agtcgaaaat
     3001 atccagaacc tgatttttgt ctatgtaaaa aattggttta tcgaaaaacc aatagctgct
     3061 aaagtatcaa gtgaaaaacg tttgaattat gcaagctccc caagcactat tacgaaagac
     3121 tggttagagt gaaactttac tgacaaagtg attgttgctt catggagtaa cattaaaatt
     3181 aaaaattttt tattattcta attatattac gaatattaca
//
LOCUS       DACBZK010000158         3218 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.165, whole genome shotgun sequence.
ACCESSION   DACBZK010000158 DACBZK010000000
VERSION     DACBZK010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3218
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.165"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            50..1438
                     /locus_tag="IVD66_002824"
     CDS             50..1438
                     /locus_tag="IVD66_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HAP6146986.1"
                     /translation="MYKERDDLNYTLIINKDGNYSWRPLVLLHPILYVDLVNCLTKED
                     HWEELKKRFSEFKKDKNINCYSIPVEASKGSKRTDLGETILNWWEYFEQKSLAQNIKY
                     QYCMFTDIADCYPSIYTHSITWAMYGKEKVKNDENKCSGSLGDKIDKKISGMQHNQTN
                     GIPQGSVLMDFVAEIVLGYVDLRLSKELKKLENLKDYKVLRYRDDYRIFSNNRNDLEQ
                     IMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKKDKLYWEEIKASIRMNATNLDGDRE
                     IRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFNKERIIKITSKPNDLLPLIGILVD
                     IMINNPGSLPQCVLIIGQLLNFENESKAREIVEMIINKYALKPNTEFMMIWFQRLTTI
                     FGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKKSFYEGTIKDEEKYIKMSKKIY
                     ITEFDDFNDYPF"
     gene            1776..>3218
                     /locus_tag="IVD66_002825"
     CDS             1776..>3218
                     /locus_tag="IVD66_002825"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HAP6146987.1"
                     /translation="MTEQIEKNSKSLYQALWNSADILRSKMDANEYKSYLLGLVFYKY
                     LSDNMLRYVSVLLEEETDDLNKAQDLYVEAFKDADIKDDLLYELKDEFSYTIAPALTF
                     TAQVAAIHDGSFQLEDLVQGFRDIEQSSENFENLFEDIDLYSKKLGSTPQKQNKTIAD
                     VMKELEGLNMAGHAGDVLGDAYEYLIGQFASESGKKAGEFYTPQPVAKLMTQIVLQGK
                     EDKKGFSVYDATMGSGSLLLNAKKYSHQPGTISYFGQELNTSTYNLARMNMILHGVPI
                     ANQHLHNADTLDQDWPTEEPTNFDGVLMNPPYSAKWSADKGFLDDPRFSAYGVLAPKS
                     KADFAFLLHGYYHLKDTGVMAIVLPHGVLFRGGAEGKIRKALLENGAIDTVIGLPANI
                     FFNTSIPTTVIILKKDRAKKDVLFIDASQDFEKIKTQNTLRDYHIDAILEAYKTRTIK
                     DKYAYVAEFDEIVENDYNLNIPRYVDTFEEE"
BASE COUNT         1183 a          505 c          582 g          948 t
ORIGIN      
        1 ttcaaaaaaa aaccaaccga aagatataaa agatattgta gatacacgaa tgtataaaga
       61 acgtgatgac ttaaactata cgcttattat caataaagat ggaaactatt catggcgtcc
      121 tctcgttcta ctacatccta ttctatatgt agatttggtt aattgtctca ctaaagaaga
      181 ccattgggag gagttaaaaa agaggtttag tgaatttaaa aaagataaaa atattaactg
      241 ttattctata cctgttgaag cttccaaagg ttcaaaaagg acagatcttg gtgaaacaat
      301 actaaactgg tgggaatatt ttgaacaaaa aagcttagct cagaatatta aataccaata
      361 ttgcatgttt actgacatcg ctgattgtta tccatcaatt tatactcact ctataacatg
      421 ggccatgtat ggtaaagaaa aagttaaaaa tgatgaaaat aagtgttcgg gctcacttgg
      481 cgataaaata gataaaaaaa tatctggaat gcaacacaat caaacaaatg gtatccctca
      541 gggttccgtt cttatggatt ttgtagcaga gatcgttcta gggtatgttg atttgagatt
      601 atcgaaagaa ttaaaaaaat tagaaaattt aaaagattac aaagtactca gatatagaga
      661 tgattataga atattttcaa ataatcgtaa tgatttggaa caaattatga aagtgttatc
      721 agaagtctta tatgatttaa attttaagtt aaattctagt aaaacaaaat tatcagatga
      781 tattatcata gattctatca aaaaagataa gctctattgg gaagaaatta aggcaagtat
      841 aagaatgaat gccacaaact tagatggtga tagagaaatt cgttatagta taaatttaca
      901 aaaacattta ttggaaataa aaaagttagc agataagcat cctaattcag gccaattgaa
      961 aaaagcactt tctgagttta ataaagaacg cattattaaa atcacttcaa agccgaacga
     1021 tcttttacca cttattggta tcctggtaga tatcatgata aataacccgg gttctttgcc
     1081 gcagtgtgtc ttaattatag ggcagttatt aaatttcgaa aatgagagta aggctagaga
     1141 aatagttgaa atgattataa acaaatatgc tttaaagcca aatactgaat ttatgatgat
     1201 atggtttcaa agattgacca ccatttttgg agaaatgttt gatagtgttt tatcatccga
     1261 atttgtatct aaaatcaaag atcctgtctc taatcagatg ttttctgtag actggctaaa
     1321 tgaagatgct aagaaatctt tttatgaagg gaccattaaa gacgaagaga aatatattaa
     1381 aatgagtaag aaaatatata ttactgaatt tgatgatttt aatgattatc ctttttaagt
     1441 gaaaatttag aatgaatata aaaaacatta caatctaatt tttttaaaaa aatgttatat
     1501 cggaagtaat ctcttgattt ctatactata agataagaaa accactattt aacaaggtta
     1561 ttcgaacctt attttaagtt acttattatt taatgtatcg aaaaaggtga aataggtttg
     1621 ttataataag aattaagtaa gacatgaatt gtctaagcaa atgtagctta tccatttcat
     1681 taaaatacat atggtgaaaa aacaagttca aatagtaact aattttttaa aaaactgatt
     1741 tataaaaaat acaacacgaa tgaggaaaat aaccaatgac agaacaaatc gaaaaaaatt
     1801 caaaaagctt atatcaggca ctgtggaatt ccgcagatat cctgcgttca aaaatggacg
     1861 ctaatgaata caagagctat ttactaggct tggtctttta taaatactta tccgacaaca
     1921 tgctgcggta tgtctccgtt ctattggagg aagaaacgga cgacctaaat aaagcacaag
     1981 acctttacgt tgaagcattt aaagatgcag atataaagga tgatctcttg tatgaactaa
     2041 aagatgagtt ttcatatacc atcgcacccg cattgacctt taccgcgcaa gtggcagcca
     2101 ttcatgatgg atcttttcaa ttagaagacc tggtacaagg tttccgtgac attgaacaat
     2161 ccagcgaaaa ctttgagaac ttatttgaag acattgatct gtattctaaa aaactggggt
     2221 caaccccaca aaaacaaaat aaaaccatcg cagatgttat gaaagaatta gaagggttaa
     2281 acatggcggg gcatgctggc gatgtcttag gcgatgccta tgagtactta attggccaat
     2341 tcgcatctga atccggtaaa aaagccggtg aattctatac cccacaaccg gtcgcaaaat
     2401 tgatgacaca aattgtttta caaggaaaag aagataaaaa aggcttttct gtttacgacg
     2461 cgaccatggg ttcgggctcg ttacttttga acgctaaaaa atattcccat caaccgggaa
     2521 ccatttctta tttcggacaa gagttgaata cgtctaccta taatttggcg cgtatgaaca
     2581 tgattttgca tggggttccc attgccaacc aacacttgca taatgcggat accttggatc
     2641 aagactggcc aacagaagag ccaacgaact tcgatggggt gctcatgaac ccaccgtatt
     2701 ctgcaaaatg gtcggctgat aaaggcttct tagatgaccc acgcttctct gcctatggcg
     2761 tattagcccc taaatcaaaa gcggactttg ctttcttatt acatggctac tatcatttga
     2821 aagatacggg cgtcatggcc attgttttgc cacatggggt gctctttaga gggggcgcag
     2881 aagggaagat acgcaaagcc ttgttagaaa atggtgccat tgacaccgtc attggcttac
     2941 ctgctaacat cttctttaat acgtccattc caacgaccgt aattatcttg aagaaagacc
     3001 gtgcgaaaaa agatgtgctc tttattgatg cgtcacaaga ttttgaaaaa ataaaaacgc
     3061 aaaatacgct acgagattac catattgacg ctattttaga ggcctataaa acccgtacaa
     3121 ttaaagacaa gtatgcttat gtcgcagaat ttgatgaaat tgtggagaat gattacaact
     3181 taaacattcc ccgttacgtg gatacctttg aagaagaa
//
LOCUS       DACBZK010000159         3197 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.166, whole genome shotgun sequence.
ACCESSION   DACBZK010000159 DACBZK010000000
VERSION     DACBZK010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3197
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.166"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            185..481
                     /locus_tag="IVD66_002826"
     CDS             185..481
                     /locus_tag="IVD66_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146988.1"
                     /translation="MNVKIRDLDPKFISEIDRRCVELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQEKFDQLLEKFSEIQSYNTKILEEYVSQNNRIIEILIEQNRGSEL"
     gene            483..905
                     /locus_tag="IVD66_002827"
     CDS             483..905
                     /locus_tag="IVD66_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146989.1"
                     /translation="MAKVIDKHIYFHQTHIDVLDEIISTHAEVKNYSEAVRFLCMNYD
                     PEVEKKVNSNQAKLNGMSKEISILTEMVSEFADLHLKDTGILIGKNSTVYQEAKERVE
                     GKIKSNQTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            924..2516
                     /locus_tag="IVD66_002828"
     CDS             924..2516
                     /locus_tag="IVD66_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146990.1"
                     /translation="MTQSPSVILTCQFTLPNKKSFSTYIDYITREQALEEKERRTPEE
                     EQELQRIKNALEEFYIPEGETFSESKTGKEFSETSNEAQSLMEHGINFDKLEEQDFTN
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSIASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWNYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            2537..2872
                     /locus_tag="IVD66_002829"
     CDS             2537..2872
                     /locus_tag="IVD66_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146991.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGNLVPYYTTWEMNEEGINNFPCKSI
                     KESISLTEC"
     gene            3009..>3197
                     /locus_tag="IVD66_002830"
     CDS             3009..>3197
                     /locus_tag="IVD66_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146992.1"
                     /translation="MVHSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGNI
                     LTLNLTTKTFVDAAEDYPF"
BASE COUNT         1265 a          465 c          638 g          829 t
ORIGIN      
        1 cccactttta aaaaaaagtg gttggatagg ctgtgcctat cacgtttctg aaaaaaataa
       61 atgaccccaa aataccaata tataggatag tacaaggata gcaaaggata gtaaaaggat
      121 agaggtagga tagcgaaaag gataggatcc ttttcactat cctatattat attggaggat
      181 atttatgaat gttaaaatta gagatttaga tccaaaattc atttctgaaa ttgatcgaag
      241 atgcgttgaa ctaagtaatc gtacaggaaa taaatggagt cgtaatgatt atttaaagct
      301 actcgttgaa aatgattttg atcgtccttt gatggaatac aaacaagaaa agtttgacca
      361 gttattagaa aagttttcag aaattcaaag ttataacaca aagatattag aagaatatgt
      421 tagccaaaat aatcgtatta tagaaatctt gattgagcaa aatagaggaa gtgaactttg
      481 atatggcaaa ggttatagac aaacacattt actttcacca aacacatatc gatgtattgg
      541 atgaaattat ttctactcat gcagaggtta aaaactatag tgaagctgtt cgctttttat
      601 gtatgaacta tgatccagaa gtggagaaaa aagtaaattc caatcaagca aagttgaatg
      661 gaatgagtaa agaaatttct attttaaccg aaatggtttc agaatttgcg gatcttcatt
      721 tgaaagatac aggaatatta attggtaaaa attcaactgt ttatcaagaa gcaaaagaac
      781 gagtggaagg aaaaattaaa tccaatcaaa caaaaaaata ttcccctcag ttgaagaaac
      841 ctgtgaatga atctgttcat gccagagtag atccatttga tccaacgaag attctaaaaa
      901 gataaaaatg aaggaggata ataatgactc aatcgccttc agttattctc acttgtcaat
      961 ttactttgcc gaataaaaag tcattttcta cttatattga ctatattaca agggaacagg
     1021 ctcttgaaga aaaggaacga cgtacgcccg aagaagaaca ggaacttcaa cgaatcaaga
     1081 atgctttaga ggagttttat attcctgaag gagaaacttt ttcggagagt aagacgggta
     1141 aagaattcag tgaaacgtcg aatgaagctc aatcgttgat ggaacatgga atcaattttg
     1201 acaagttaga ggaacaagat tttaccaatt atctttctta tatgacacgt cactatgcgt
     1261 tagaacaaaa gaaagaactg acgcaaagtg aacaaaaaga ataccaacgc ttgaaccaag
     1321 caatgaaaaa atatcaaaca gaaccccata aaaaagcttc aggaaatctt cctggagttt
     1381 tttctatagc ttcagacgaa gtgaaaggaa gtgatctgaa ggagattaag caaatcttcc
     1441 aaagaggaca acaaaaaggc tcaatcattt atcaagatgt tgtttctcat gataattcgt
     1501 atcttgaaaa aataggattg tacgatccca aaacagatac tttagatgaa gaagggttaa
     1561 aagcagctgg aagaaaaatg atggagacat tattcgagaa agagcaactg aacgaaacag
     1621 gctactggat ggcaacgatt caccgtaaca ctaaacatat ccatattcat tttgcagttg
     1681 ttgaaaaaga aaatacgcgt aaaccttaca cggaggttga aaatggtgtg agttatatcg
     1741 taccgaaagg taagagaaga caagcaacat tagacgcaat gaagaccaat tatgtacatg
     1801 agttagaacg tttttcttat gaaaaggatc gaatgattgg tatggagaaa cgaaatttat
     1861 tgacgcggaa aagtgatttg cgtaacacct taacaaaagt ggtaaaagag ccagcgcgtt
     1921 acgatcgaca cgcgatgaac ttattaaatg aagtatataa aaccctacct gacaaacgtt
     1981 cggaatggaa ttacggggat gaaaaacgaa ccaaactttc accatacaca agagagaaac
     2041 tcgatgagtt aaccaaatat gttttaacaa aagaacctga atatcaagaa tatatacaga
     2101 tttcaaaagc attgaaagaa gaagcaaaaa gtctttatgg ggaaagcaag agagaatcaa
     2161 aggatgcaga gaaaaatgct ctctttgatt taaaaaagcg cacaggaaat gccatcctaa
     2221 cagagctgaa gagacaggat agtcaaataa aaccattaat agaaagtgtt gatcagatgc
     2281 aatctattta caatgaacga tcctttcgaa cgcttaaaca attgccaacg aatgaataca
     2341 aatatagtta cgaagaattc atgaagcgca ggaaacaatt ccaacaaaga gttgtcacgc
     2401 agcggagttt gcgtcaatta aatcgaacga ttaatgccca tgaagaaaaa taccacgcaa
     2461 gtaaagcata cgaagagcaa caacgaagaa ttcaaatgga acaagaaaga cagtaaagac
     2521 agtaggagga atagcaatga aacaatattt agatcaatgg aaagttatag aaggatcatt
     2581 aagagaagaa cgaatcgaac aacttcctga ttgtttagaa aaagagcatt tgttccagat
     2641 aagagaaatg ttgagaaacg aacagtttga tccaaatcaa tttttagtcg ttgagtaccc
     2701 agctactggt gtgtattgtt gtaatcatgt gaagggtgaa aaatatttta tcattcaaga
     2761 atatgaaggg aatttagttc cttattatac tacttgggaa atgaatgaag agggaatcaa
     2821 taactttcca tgtaaaagca taaaagagtc tatttcactc acagagtgtt agttattaag
     2881 tgaaaaaaag agtcctgaac gtgattgtcc aggattcttt ttttcaatga attgttttcc
     2941 gccaattcat tgagtggtgc gatttgcgac tacattatat caaaagaaag agaagggagg
     3001 aagaagaaat ggttcattca acgattggag ttgttgttga aaaaagcaga gataatctcg
     3061 tttttgtgac agaaattcaa acgggcagag cttttgtcgt cacagacaaa gcggcaaaag
     3121 cttatcaaag tggcaatatt ttaacgttaa atctgactac gaagacgttc gttgatgcag
     3181 cagaagatta tccattt
//
LOCUS       DACBZK010000160         3177 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.167, whole genome shotgun sequence.
ACCESSION   DACBZK010000160 DACBZK010000000
VERSION     DACBZK010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3177
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.167"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(7..978)
                     /locus_tag="IVD66_002831"
     CDS             complement(7..978)
                     /locus_tag="IVD66_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HAP6146993.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            1684..3063
                     /gene="brnQ"
                     /locus_tag="IVD66_002832"
     CDS             1684..3063
                     /gene="brnQ"
                     /locus_tag="IVD66_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAP6146994.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMPLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
BASE COUNT          892 a          634 c          593 g         1058 t
ORIGIN      
        1 caaagcttat tcttgatgga gatctgcctt ttcataagct ttgatgattt cggcaactac
       61 agggtgccga acaacgtcac ttgcttcaaa attaacaaaa tcgattttct tgatttgctt
      121 taatgttcgt tctgcatgaa caagaccact tgttgtccct cgaggcagat caatctgact
      181 cgtatctcca ttgacaatca tttttgattg ataaccaaga cgtgtcagga acattttcat
      241 ctgagcaact gtcgtgttct gtgcttcatc caaaataacg aatgcatcat ccaatgtccg
      301 cccccgcatg taagctaaag gagcaatttc gatcacgcct cgttccatca atcggttcgt
      361 atgatctaat ccaaaaattt ggtataaagc atcataaaca ggacgcagat aaggatctac
      421 tttttctttt agatccccgg gaagaaagcc tagattttcc cctgcttcca cagcaggccg
      481 cgtcaaaatg attttttgca cttcaccttt tttcaaggca gcgattgcta atactactgc
      541 aagaaaagtt tttcctgtcc cggctggtcc tacgccaaat acgatatcat gtttggctac
      601 cgattcgaca tatttctttt ggccgctgtt ttttacccgt attggttttc cattacggtc
      661 tttgacgatc tcttcctcat acatttcaac aaaataatct aatgtgcctt tttgccccat
      721 tttcagtgcc gtcacgacat ctggtgtact tacatggatt cctcgtttga tcaattcctg
      781 caatgtccga atgactgagg cagccaagga aatctgggat tgttcgccaa tgatctgaat
      841 gatttctcca cgtgtatgga tggttgtttc tgttgtttct tcaatcagtt ttatatgctt
      901 gtcgtgtgca cctaaaagca tgctgacatc atcagcagcc gtcaatctaa tctctaaaga
      961 actagactct tccgtcaaaa atagacatcc cctttttttc gattcattct ttcctatttt
     1021 accatactca gaagaaacta tatagcaaat aagaaaaggt tctaaaagag ttgcttaacc
     1081 ataagtacca agaaacgtta aaaaatagct gcttccattc tctaaaggtc tcgtttgaat
     1141 aaaaaaagct gatcatgtaa gctatgcata agatagagga caagtattcc gtctaactta
     1201 gcaagtattc tctgggtatt tttcttgttt caaaaaaaga aaacaaaata tttgaaatat
     1261 tcttgcattt caaaaaaaac aggtgtatta taacgtcaac aaataaatat acagcaaagc
     1321 gtcgaggaaa acagtaggct attcagcgat ttattcccag tgagtcatgt aagtgagaaa
     1381 tgacaataaa tcgaatagac gaacatcatt tccgagtcaa tgtcgaaaac gtagatcatt
     1441 gtggctgcct ccattatcag gctagcggat aactttatcg aaaagcgtcc gtgaatgaag
     1501 aagctttttt aagcgaaaaa aggtggtacc gttctagaat ctagagccct tttcccaagt
     1561 ggaaaagggc ttttttttat attttaaggt ggtggttttc atggaatctg atattagtgg
     1621 catttctagt ttctgcaacg tttattttgt tactcaaaat gataattatt ggaggaaaaa
     1681 tttatggaag aaacaaaaac ttattcatgg aagcaattat tgatggtcag ttcacttatc
     1741 ttcgggatgt tcttcgggtc aggtaatctg atctttcctg tccacttagg tcaaatggct
     1801 ggatcaaact ggatcagcgc tggtgtagga tttgccatct caggcgctct tttcccatta
     1861 ttagctatct tagctgtagt agtgacaaaa agtgatggtc tgtatgactt agctaaacct
     1921 gtcggaaaat ggtatgctgc cttgttcttg atccttgttc atttaacgat cggaccattc
     1981 tttggtacac cgcggacagc agcaactgct tttgaaatgg ctgctaaacc ctttttgcct
     2041 gaaaaatatg attcattagg tatgttttta ttctctgctc ttttcttttt acttgcttat
     2101 ttccttactg tacatccaac acgtttggtc aaatatgtcg gaaagtattt aaactccttg
     2161 tttcttgcat tattagctat catttttgtc gtttctttat tccaacccat ggggaatcta
     2221 aaccaatctg ctgcagattc ttatcagacg aacgctttga caaatggcgt tttagaagga
     2281 tacaacacgg ttgatgcagt agctttactt gctttaagtg tcacttttgt ccatgcagtt
     2341 cgtgatcttg gttttaaaga taaaaaagtc acagaattaa cagcaaaagc tggtagcctg
     2401 agcgttgcgt tagaagtcat gatttatttt ggtctggtcc ttctcggtgc gatgagtttg
     2461 aataagatgc ctttatcaga aaatggcgga actgcacttt ctcagatcac taatttttat
     2521 ttaggtaact tcggtgctag cttcttaggg gtaatggtca cattaggtgt cttcactacc
     2581 gctatgggac tcgttgtttc ttttgcacaa gatttccata aactgttccc taaagtcagt
     2641 tatatgacat ggctgcggtt aacgactttt gtctcttttg tcgttgcgaa tgccggattg
     2701 gataatatca tccaatggtc tttaccagta ttgatgcttt tgtatccatt gtcacttgcg
     2761 ttaatcttgc tttccttaac agcaaaattc ttccaaaaga gtccatttgt ctatcaagta
     2821 acgatgttct tttctgccgt tccagccgta ttggatatgt tggcaaattc gcctgcatta
     2881 gtgagtcagc aaactgtcgt agcaagctta ctaggatttt atcatcatca cgttcctttt
     2941 gctgcattag gacttggctg gatggtccca acgttacttg gttacgctgg cagcttactc
     3001 ttttattacg cctatcgcct atcagggtat aaacaagaag caaatgaact accagaagaa
     3061 taaccaaatc aaacacaatt taacataaga gatattaaac aggaaaaaaa cagctagaag
     3121 aaagaataag attctttctt ctagctgttt tttagttctt tttttacgaa cacaaaa
//
LOCUS       DACBZK010000161         2963 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.168, whole genome shotgun sequence.
ACCESSION   DACBZK010000161 DACBZK010000000
VERSION     DACBZK010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2963
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.168"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..293)
                     /locus_tag="IVD66_002833"
     CDS             complement(<1..293)
                     /locus_tag="IVD66_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146995.1"
                     /translation="MLIEGKTQLWFKFDPSNRFIKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPER"
     gene            272..679
                     /locus_tag="IVD66_002834"
     CDS             272..679
                     /locus_tag="IVD66_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146996.1"
                     /translation="MSFLLLKYLEIYSVKKNKLIGENDSPIKTPIELSLRNRMGILQR
                     SEIVKELFYHKFSYEIRLDDTYEHYRIVFFVYNSIEDATATTALTFGFTKNGTINSDK
                     TRQAATESDDICKKVCNGEENYWIGEEKLNEIY"
     gene            666..1118
                     /locus_tag="IVD66_002835"
     CDS             666..1118
                     /locus_tag="IVD66_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146997.1"
                     /translation="MKSINDLLKKHPDLYKKLNSEQRNLSKQLLKIRLKKQKNVTEFS
                     KMLGISEKKYLEFEFGDMHIPVAEYNKLLKQVENLSYKDSMNFTIKVAGGPIKYDRIE
                     NKPYIRNKSYSVFKSRKRKEVSSNMVYASVNYQDTSRYIVEKEVYVHG"
     gene            1111..1509
                     /locus_tag="IVD66_002836"
     CDS             1111..1509
                     /locus_tag="IVD66_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6146998.1"
                     /translation="MDKGNSVTFALENISLNKIHFELTDNFSYGDLEFNIELGYKEDE
                     AEYLEKKLVSLRAHIVGGMEGAPVDILLFSVIRVSTNEQPYKKLVEESMGELAKPILN
                     KASNLISNLYSEVGVMPTVIDLYQLYSQQK"
     gene            1821..1894
                     /locus_tag="IVD66_002837"
     tRNA            1821..1894
                     /locus_tag="IVD66_002837"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1855..1857,aa:Ile,seq:cat)
     gene            2274..2435
                     /locus_tag="IVD66_002838"
                     /pseudo
     CDS             2274..2435
                     /locus_tag="IVD66_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
     gene            2585..2785
                     /locus_tag="IVD66_002839"
     CDS             2585..2785
                     /locus_tag="IVD66_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP6146999.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT         1065 a          423 c          546 g          929 t
ORIGIN      
        1 tacctttctg gatcaacgaa agtatacttt atatagtcat aacgccgatg atcgctacgt
       61 gcgtccggca cgtcagtcac gatatcaaac aaaaagtata catctttctt cattctagtt
      121 tttgcagcag ggattttaaa gtagttctta ttagaatagt agagattgat taataagcta
      181 tcttcgattg ctagaaagaa aacttctgaa tcccacacct tataaaaatc tttgataaat
      241 ctattcgaag gatcaaattt aaaccataat tgtgtctttc cttctattaa aatatcttga
      301 aatttactct gttaaaaaaa ataaattaat tggtgaaaat gattctccaa taaaaacacc
      361 tattgagcta agcttaagaa atcggatggg aatactccaa agatcggaaa tagtaaaaga
      421 acttttttat cataaattta gttatgaaat aagactagat gatacttatg agcattatag
      481 aattgttttt ttcgtataca attctataga agatgctact gcgactactg cattaacatt
      541 cggttttacg aaaaatggaa caatcaattc ggataaaacc cgtcaagctg ctacagaaag
      601 tgatgatata tgtaagaaag tatgcaatgg ggaagagaat tactggatag gggaggaaaa
      661 gttgaatgaa atctattaat gatttattaa aaaaacatcc tgatttatat aaaaaattaa
      721 attctgaaca aagaaacctg tccaaacaat tacttaaaat aagattaaaa aaacaaaaaa
      781 acgtgacaga attctcaaaa atgttaggaa taagtgaaaa aaaatatctt gaatttgagt
      841 tcggagatat gcatattcct gttgcagagt acaataaact tttgaaacaa gttgaaaatt
      901 tgtcctataa agattcaatg aatttcacta ttaaggttgc tggcggccct attaaatatg
      961 accgtattga aaataaacct tatattcgga ataaaagtta ctcagtattt aaaagtagaa
     1021 agagaaaaga agtatcgtca aatatggtct atgctagtgt taattaccaa gatacgagcc
     1081 gctatattgt agaaaaagag gtatatgtac atggataaag gaaatagtgt tacttttgca
     1141 cttgaaaata ttagtttgaa taaaattcat tttgaattaa ctgataattt tagttatgga
     1201 gatttagagt ttaatattga acttggatat aaagaagacg aagcagagta tctagaaaaa
     1261 aaacttgttt ctttacgagc tcacattgta ggggggatgg aaggagcacc ggtagatatt
     1321 ttactctttt cagttattcg tgtttctaca aatgaacagc catataaaaa attagtagaa
     1381 gaatctatgg gagagctagc taaacctatc ctgaataaag cttctaattt gatttctaat
     1441 ttatatagcg aagtaggagt tatgcctaca gttattgatt tatatcagct atatagtcaa
     1501 caaaaataaa atacaagtaa tagagttatc tatttaaatt tgcaagacaa agacctcaac
     1561 cagtcatcct tggttgaggc ttttttgctc tgtaattaac tcgtatagat cctgcaagat
     1621 agtttgtttc tgaataaatg attgatatga agtatttaga tgactgtatt gacaactata
     1681 aaaatcattc gataaaatag tgatgttatc gcatatcttc actatcaccc ataatagtca
     1741 cactccaagc tatgcgataa caggtttgtt gccacacatt ctactggttg attgtttatg
     1801 gctttatgtg gcaacaacca gtacccttag cttagttggt cagagcagac ggctcataac
     1861 cgtccggtcg taggttcgag tcctacaggg tacataattt aatctatttg ataaaaaata
     1921 aaattcaata atggtataat aaaatatcgg ctcgtcgctt ccacagagat tttcgtggga
     1981 ggaggtgtat gatttgtttg aattcacttt ggagcacgtg ctcttgccat tgttaattgg
     2041 tttaactttg gcattattta gtcattggct agataaacat tagagccgac aatggcgctt
     2101 actgtttcgc agcggtaagc gtcttttttt gaaaaagaaa aaaacacaac gtattcgcag
     2161 gtacgttgtg tttatggtgt atatttgttt aaattcactt tcaattatta ttatacttgt
     2221 taaataaatt gtgtcaatat aaaagatatt tttatacgtg tactaaccta tattatcctt
     2281 ctggtaatgt tattccatcg cagcaggata tgaattttac caaaaggata caaaagtgtg
     2341 gagaaatgat ggggatcact gtactggacc acttgatcat cggacgcaaa cgatatttta
     2401 gtttgagaga agaaggaatg atggaagaga agtaagttgc tttcttgcaa aaaaaatgaa
     2461 gcaagtgtac aattatattg taattttgtt tgggaataga agttgaaaca tctgttgcac
     2521 ctctatcgta cacgagcaat gttacaattt aaattagtgc ttttggcacg aggaggatat
     2581 tattatggaa aacggaacag taaaatggtt caacgctgaa aaaggatttg gatttatctc
     2641 acgtgaagat ggaagcgacg tattcgttca cttctcagct atccaaggtg acggattcaa
     2701 aacattagaa gaaggtcaag cagtgacttt cgacgttgaa gaatcagacc gcggcccaca
     2761 agctgcaaac gttgtaaaag cttaatttta tctgtaaatc aaattgatgg tagacatcaa
     2821 tttttacgag agaacaaagc gagtaacaaa aatacctgcc acaagagaca atttctcttg
     2881 tggcaggtat ttttttgtat gaaaaagtaa ataaatttaa gaggctatga aagagccacc
     2941 ttgtatcaag gaataagaac aaa
//
LOCUS       DACBZK010000162         2959 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.169, whole genome shotgun sequence.
ACCESSION   DACBZK010000162 DACBZK010000000
VERSION     DACBZK010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.169"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..1578)
                     /locus_tag="IVD66_002840"
     CDS             complement(<1..1578)
                     /locus_tag="IVD66_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAP6147000.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRL"
     gene            complement(1741..2334)
                     /locus_tag="IVD66_002841"
     CDS             complement(1741..2334)
                     /locus_tag="IVD66_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147001.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLVTKE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            complement(2335..2667)
                     /locus_tag="IVD66_002842"
     CDS             complement(2335..2667)
                     /locus_tag="IVD66_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147002.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            complement(2717..>2959)
                     /locus_tag="IVD66_002843"
     CDS             complement(2717..>2959)
                     /locus_tag="IVD66_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147003.1"
                     /translation="NLTTVSYNLSESGETENASVQNIVTREAEPKPIQNVHTGYKPAN
                     VAFTAPTKINVTRDTKNRNNALKEQLLRDIKQDIKP"
BASE COUNT          786 a          628 c          492 g         1053 t
ORIGIN      
        1 taaacgtcgt tgtcttcttc cttgaatcaa tgcctgattc caaatcaacg tcatagccat
       61 gtacatttga cattgttgta cccctcgatc taagcctgta atagagtcaa tgtcaaaaaa
      121 gaccaactgt tgttggtcaa ggtgtcgaat cgtactgtga ccatcaaaaa tcatgccata
      181 cgtctcacat aaggattcta cgatggattc catttcttct tttcgattct ttttctcttg
      241 ggaagcacct ggtaattcca gttgtcctaa aaagtctaaa aattctttga acgtcggata
      301 agcttctgga tctttccctg tgacttgcgt ctcagtattt gaacgcgaat ttgaggaagt
      361 aaagccgcgt ggtactgttc catactcttc ataaaaacga tttaagtagg tcttaaattc
      421 tgctttcatc gttcctttta gctgaggact cactaactgt acctgataga ctactttgtc
      481 taagtgtgtt tgataggacg ctgcttcatt gatcttcaaa tctttgactg atccatcgtc
      541 atataaactg gatgcttcat catacgtccg tgtggcaaat atttctaaag gattgatcat
      601 cccgtcagac ccgtctaagc gcaccataat gccgttatat tcctttaaga aggggataaa
      661 gtctttcccc ttttcaaagc cccaaataaa gtctcctgca gctaaatggg cttccgcgat
      721 cattttaaga acggttgatt taccagctcc catcattcct agaagcaagg tattagtaga
      781 caaccgcaca ctatttttat atgtcgcatt ccagacaaat gggccacctg tcatggtttc
      841 cccatattga gtccctcctg gatcttttag cgtttggtgg tggaacggga atcctccgcc
      901 aatatttaac gatggtagtg attgcccttt gatatttcca aaccattcag cttgttcatc
      961 gaacatggta aacatcgatt gccaatctct tttcgttttg tgcagatagg tcactgcacg
     1021 ataatccatc ccttttaaat tttcaatcag ttcctgcgct cgttcatcta cttcttgaat
     1081 cgtgtttccg taaacatgta ctctcacttt gacttgctta gaaatttccc cattagaagt
     1141 caatttacga gcatattccg ctagttccag gtattcttct gcgcttttat ttcggtcagt
     1201 cgcttttcgt tcattatctg atcgatcatt taattcatct aaggcacgat tgatttgatc
     1261 aatcactttt tgcttttcat ctgtgctaac atcgagtgtg gccactgtat gaggattgtt
     1321 catgagattg gccaaccaaa aaagcgtagg attttttgtg tagtgataaa ctgtcacaca
     1381 tcgtgaataa ccattaccat acgtcacata ttcttcatca aaatttaacc caccttgtgg
     1441 catcacttgt tttaaaaaat ctaaatcata ccctttggat ttcaaaattt ctatttcccg
     1501 atttcctagt tgctttaatg gatcaagtac tttttgatca ttttgtggtg aaaaagctgt
     1561 tttaattgct tctaacatgt acagtcacct cttcttgttt gattctttac ttggttaaaa
     1621 gattgccctt ttcccaactt acccaggctt aaagtgtgag gaaattttct agtggtctct
     1681 tccttcggaa catctttttc taaccatatc aatggatatt tcattctctc ttctccattc
     1741 ctactcatca ttcatattgt tcattcgata cagaatcttg atcaattctt ttttgtagag
     1801 tggttttaac cctaaaatgc cactagatcg cattaactga cggtttctgg tttgtaaatc
     1861 cttgattgtc tttccttcaa tgacgaaaaa gaagcttaag tcaggacgtt cttgttctgc
     1921 tcgtttcaat tcctggattt cttcgactaa tttcttttca tattttttta atcgttgtag
     1981 atttcttcct aaggattgtt ccatacgatt cttatctaat aactgccgct tttgcacgat
     2041 ttgttccgtt agatccgtct ctgtagtcaa actaactaac ttaattgttg gcacatacgt
     2101 acgcatgacg gtggtcaact gattcattcg ttccagtttc tcttgttcat ttaatccctc
     2161 cacgtcagtg gaaacgacac gataataacg ttgaaaatga tcttctttag taactaagac
     2221 tccctcttct gtacaggatt tataaggaaa taaatccaag atagatcgtt cttctggttt
     2281 tccaaactgc aaaatagatt tcttatcaac tgaattttgt cctttgactc gcatttattc
     2341 atcctcctta tacgtaccat gataatttcg gttaggatct aacgcatgat aatggttctt
     2401 gtccgcaaaa aaaatagact cgataatcgc aaaaatttgt cgttgacctg ggttattata
     2461 gggtcgccaa acaatcacta acgctatcgc aatccataag ccataattca agagtgcaaa
     2521 aaagagtggt aagtggacaa gattattgac cattttcgcc caaaaaaagc agccaccaag
     2581 cgttaataga tctaaaaaga aaaaagcgaa aaacttccat tctccactaa atcttggagg
     2641 gtttttcatg tttatatatt tatccataat tgatttctcc ttttcatata aagaaaaggc
     2701 ctaacttgta ggccttttat ggtttgatat cctgtttgat atccctcaat agttgttctt
     2761 tcaatgcatt gttcctgttt ttggtatctc ttgtcacatt tatttttgtc ggtgcagtaa
     2821 atgccacatt tgctggcttg taacctgtat gaacgttttg aataggtttt ggttcagctt
     2881 ctcttgtcac aatattttga acggacgcat tctctgtctc accactttca gataaattgt
     2941 aagaaacagt tgtcaaatt
//
LOCUS       DACBZK010000163         2953 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.170, whole genome shotgun sequence.
ACCESSION   DACBZK010000163 DACBZK010000000
VERSION     DACBZK010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2953
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.170"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            89..406
                     /locus_tag="IVD66_002844"
     CDS             89..406
                     /locus_tag="IVD66_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAP6147004.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(497..862)
                     /locus_tag="IVD66_002845"
     CDS             complement(497..862)
                     /locus_tag="IVD66_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147005.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1069..1551
                     /locus_tag="IVD66_002846"
     CDS             1069..1551
                     /locus_tag="IVD66_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147006.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSTFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1748..2638
                     /gene="pstS"
                     /locus_tag="IVD66_002847"
     CDS             1748..2638
                     /gene="pstS"
                     /locus_tag="IVD66_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HAP6147007.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1008 a          460 c          566 g          919 t
ORIGIN      
        1 ttttaaaaca tcacaaggaa aaacttaact atggtattat ctaaacataa ttttttcggt
       61 atttaatatt taattaggag gtaatatttt gcttttttat agtaatttta tcttaatagt
      121 agcgatatta ttacttctga atatatggat ttttgatagg agtagaaatt caagtatagg
      181 ttttagaact aaacgaagtt tgtcttctaa aaaaaattgg gtatactcac aaactatttt
      241 ttatggagga attgttttaa ttagtttact ttcttcaaca ctttattctt tgaatattat
      301 agatgtttcc acctcaaatt caatatctat tattggaatc attattgctg caattattac
      361 acaactgttt ttagtgtttg gagagaagaa aagaagtaaa aaatagaaaa actagtgata
      421 gttttggtga tataagaaaa acatatatgt ataaaaagaa gaaagtagct tctctttgta
      481 catatatggt ttgtttttat ggatgccgag cttttttata agataaggct accgcccata
      541 acgacccaag gatttgtgga actaagtaaa tacctgcaag aagcaagatc agctgggtcg
      601 gttttaaagg atgatagaag taacgccatt cagtaaaatt ggcgcaaaat aaataggaag
      661 tgacagtaga tataatattg gcaatgaata aagatataat acgcctgttc ctttgaaaat
      721 aatatccagc aaaaagagat aaaaatatca atgtgatgaa cccgcttacg gaatgataac
      781 gaaaatcaag cagtaaggcg aaatgcacat aaggaacaaa agataaaagc aacggaaggt
      841 ttttccagca agtttttatc atctttcatc accacctaac aagtgttatt attttgttag
      901 ttttattgta aattgaatcc tgcaataatc aattactttt tcattatttc tagattaaat
      961 gaataaactc tcatgccatt atctctaaaa aaaagttttt ccccctaatt tttttagata
     1021 gaaaattgta tagtatgatg agagaaaaag tagtttgggg gaacgttaat gagaagaaaa
     1081 gcagtaatcg atcggcttta tttatttttt tggttttttc ctatcgtttt gctacctttt
     1141 acatgggtaa atgctgttgt acaaggtgcg gagatattag gcctgatcca aggaagcgga
     1201 tttgtggttt ctaggaattt tccagctttg attgttttct atttagtgat aagtgtaggt
     1261 ctcttattac caaaatctct gatcaatcac tacaattggc agctgcttta cttttcttgc
     1321 ttattagtat ttacatctac gttttctttg ctgcctcgct tgattatcgg ccctaatggt
     1381 ttgagcgaga gtggattgaa ggatttagct tattcctcca tgtatttctt gacgatcaaa
     1441 ccatggttct atttagtaat tgcctcattt attcttgcaa cattttttta cttctggaca
     1501 gaaatcagga taaaaagtga acgatctgta tctataaaaa ataactattg atggtggatc
     1561 atcagtaaaa aaacatatga gctgcgtaaa atgcatgttt ctcatatgct ttttttatta
     1621 ttatgtaaag aatgcgaaaa acgtttacat gatttttaca taacttaact atatttttac
     1681 agcaaccata cgagggattt acagtcgact gataaacttt agttgtaaat aagaaaggag
     1741 caataaaatg aaaaaagtat tgtttactct aggtatgatg ggaattcttt tagccggatg
     1801 cggctcagga tcaggaaata cagatggctc tgccacacaa aataattcaa gtgactcaaa
     1861 tgaacaagta aaaatcgttg cggtaggttc gacagcatta cagccgttag tcgatgcagc
     1921 acaagaaagc tttgtacaag aaaatccaaa ttatcaaatc tctgtacaag gaggaggaag
     1981 cggaactggt ttgagccaag tcgaagctgg agcagttact atcggaaact ctgatgtatt
     2041 tgcagaagaa agagacggag ttgatgcttc aaaattagtg gatcataaag tagcagtggt
     2101 cgggatggca ccaatcgtca ataaagatac agatgtcaaa gatatcacca aacaggaatt
     2161 gattgatatc tttacaggaa aaatcactaa ctggaaggaa gttggcggga aagatcaaaa
     2221 aatcaacgtc gtgaaccgtg caaacggcag cggtacccgc gcgacattcg aaaaatgggg
     2281 actggatggt gctacccctg tgcagtccca agaacaagat tcatcaggaa cagttcggca
     2341 gctggtaagt caaacaccag gagcaatcag ctatttagct ttctcatatc tcgatgattc
     2401 cacacaagca ctaagtatcg acggtgtaga accaaaagaa gagaatgtag cagataacag
     2461 ctggggaatc tggtcatatg aacatatgta cacgaacgga aaaccttccc ctgaagtcca
     2521 aaaattctta gactacatga tgacagaaga aatccaagaa ggacctgtca aagaattggg
     2581 ctatttacca atcacaatga tggaagtaga acgtgatcac gaaggaaata tcaaataact
     2641 agcagataaa catgccacgg tagtcgttac tattaaggaa aaatcaacta tgtttcccca
     2701 catatacatt tttcctttaa ttgtgaaaaa tagttcctca tattttgccg ttttttgagc
     2761 taataccgag ggtcagctga ttgaacaccg tttattcgaa aaaaagagct acgacataga
     2821 actgtcgtaa ctttttttgg ctcttcgtca aatcgtgttg gtgaagacaa atttgaataa
     2881 aacttagacc gatatgcggc gcgttctgtg cgccgcatat ttttttagtt ttcaaagatc
     2941 agaccttgtt gta
//
LOCUS       DACBZK010000164         2753 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.172, whole genome shotgun sequence.
ACCESSION   DACBZK010000164 DACBZK010000000
VERSION     DACBZK010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2753
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.172"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..193
                     /locus_tag="IVD66_002848"
     CDS             <1..193
                     /locus_tag="IVD66_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147008.1"
                     /translation="GRMSELGYSMMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPL
                     VPKGYDFLDSISKLEKMND"
     gene            271..945
                     /locus_tag="IVD66_002849"
     CDS             271..945
                     /locus_tag="IVD66_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6147009.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            1178..1612
                     /gene="dcm"
                     /locus_tag="IVD66_002850"
     CDS             1178..1612
                     /gene="dcm"
                     /locus_tag="IVD66_002850"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAP6147010.1"
                     /translation="MRFLDLFAGIGGFRLGMEQASHHCIGFCEIDKFARRSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQRFSDTRGTLFFEIARF
                     TTLLRPKLLFLENVRGLLNHEGGATFETILRTLDGLGYDVEW"
     gene            1613..2320
                     /locus_tag="IVD66_002851"
     CDS             1613..2320
                     /locus_tag="IVD66_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAP6147011.1"
                     /translation="MLNSKAYIPQSRERIFLIGHSRDACTEQVFPIIGPSSTSDQNIR
                     NLVNINPSNRGMGGQVYGSDGVAPTLTGDEGIKIALPARDGISVAGLLPGKFEQGNRV
                     YEVTGTAPTLSTKQGGTKIMIRKNETEYQEVKPEDSVNLAFPNSTSRRGRLGKQSVHT
                     LLTGDQQAIVTDQYQIRKLTPRECWRLQGFPDWAFDRDSQVNSDSQLYKQAGNSVTVP
                     VIFDIARRLKELDVHGL"
     gene            2310..2600
                     /locus_tag="IVD66_002852"
     CDS             2310..2600
                     /locus_tag="IVD66_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147012.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
BASE COUNT          895 a          458 c          634 g          766 t
ORIGIN      
        1 gggtcgtatg agtgaactcg gatattccat gatgtttggg gaggtcgaaa aaaacttctt
       61 tatgaagcac atcaaaggtc gaggttatgt ggatacaggt ggcagtgtga ttagtgagtt
      121 ttatacgcca cttgtaccaa aagggtatga tttcttagat tcaattagta aattagaaaa
      181 gatgaatgat tgagtgatct tcaatactga ctttatactt caagtaacgt ataatacttt
      241 tatatagtag gaagaaaggg gataattaat atggaaagta atgattctta tttagagtat
      301 gcaaaagcaa ataaggataa gtttatttct tatattatca aagggaaatc ccccgaagtt
      361 ggacgagacg cagtttttat ggcagggagt cctggggctg gaaaatcaga ggttgccatt
      421 ggattagctg agaattatga taaccatgtg attattgatg cggattactt tcgcacccag
      481 tttcctgatt ataatggaaa aaactctagt ctctttcaaa aagcatcttc ttggttggta
      541 gagcaggcat ttagatatgt cttagatcat ggctattctt ttattctgga tgcaactttt
      601 gcaatattaa gtgctgaaaa aaatatctcg cgggcgttga aaaaacattt tcgagtgacg
      661 attttctatg tttatcaaga ccctaaaatc gcttggaaat ttacacaaga acgtgaaatt
      721 gcagagggac gtcatgtgcc gaaaaaggca tttattaacg cttttttcaa atcaagagag
      781 aacattgcaa aagtaaagag taaacatcca gatgtattgc ttcatatcat aataaaagat
      841 tatacgaata atatttccga agttcattat gctacggata atctagaatt atttttacca
      901 ctagggtata gtaggaaaga tttggaggtt caattacatg actgagaaag aacaagtaac
      961 gaaaattgta aagaaataca ataagagcat tgcggattta tcggaaaatg ctactgcaaa
     1021 agagttcaaa acggtgatta aatatgtagc cgatcaggcc aatgaaaaac aacggaaatt
     1081 agttggatta aataaaaaat agtaggacaa attaataatg tatgagccaa gagcaaaatg
     1141 ttcttggctt ttttctttgc aatgaatgag gtaatgtatg agatttttag atttattcgc
     1201 cggtattggt ggctttcgtt taggtatgga acaggcgagc catcattgta tcggtttttg
     1261 tgaaattgat aaatttgcta gacgtagtta taaagcaatt catgatacaa gtaaggaggt
     1321 ggaaatgcat gacatcacaa gtgtatcaga tgagtttatt caatccctcg gaccagtgga
     1381 catcctttgc ggcggatttc cgtgccaagc tttttcaatt gcgggaaagc ggcaaagatt
     1441 ttccgatact cgaggtactt tattctttga aatcgctcgg ttcaccactc ttctccgacc
     1501 taagctttta ttccttgaga acgtccgagg attgctcaat cacgaaggag gggctacgtt
     1561 cgagacgatc ctccgaacgc tggatggatt ggggtatgac gtggagtggt aggtgcttaa
     1621 ctcaaaggcc tacattcccc aaagccggga gcggatattc cttatcggac attctcgaga
     1681 cgcatgtacc gaacaagtat ttcctatcat tggaccgtct tcaacatctg atcaaaacat
     1741 cagaaatttg gtaaatatca atccttccaa tcgaggaatg ggtggacaag tctatggttc
     1801 agatggcgta gcgccaacct taacaggtga tgaaggaatc aaaatcgcac tgccagcaag
     1861 ggatggaatc tctgtagcag gactattacc gggaaagttt gaacaaggta atcgagttta
     1921 tgaagttact ggaaccgccc ccaccttgtc aacgaaacaa ggtggtacaa aaatcatgat
     1981 tcgaaaaaat gaaacagaat atcaagaggt gaagccagaa gacagtgtga atctggcttt
     2041 tcctaattcc acaagtcgcc gaggtcgtct gggaaaacag agtgttcata ccttactaac
     2101 aggagaccaa caagcgatcg tcacggatca gtatcaaatt cggaagctaa cacctagaga
     2161 gtgttggcga cttcagggct ttcccgattg ggcttttgat cgagattctc aagtcaattc
     2221 agatagtcag ttgtataagc aagccggaaa ctctgtaaca gttccggtca tttttgatat
     2281 tgccagaaga ttaaaagagt tggatgtaca tggtttatga tgagttgatt ggagaaattt
     2341 attgggtgat tggaaagatt cagtcagacc cagaattaga agaacaattg cgacggttaa
     2401 aatttgatat tcgcaagaat ggtgtcaaag tcgctggcga tccatattta atgaatgagg
     2461 agacggatgc tcgaattgaa ataaatcaag taattgcaga atttgagcgg attgcggacc
     2521 aagcaaaaga accagatatt cgtcaatact tgttagaaat gaaagcagag ttggaagtaa
     2581 atggtattac agatgagtaa cctaaaccaa cacaactgac tgttaggcgc tgaccgcgga
     2641 ggattcgcga agcagaaatc ctccgtggtg ctgtgcctgt tcatggacgg cgttagccga
     2701 ccatgatgtc tcacccccgt atctaacagg ggggtacaaa aacacaaaaa ata
//
LOCUS       DACBZK010000165         2733 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.173, whole genome shotgun sequence.
ACCESSION   DACBZK010000165 DACBZK010000000
VERSION     DACBZK010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2733
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.173"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            121..1209
                     /locus_tag="IVD66_002853"
     CDS             121..1209
                     /locus_tag="IVD66_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAP6147013.1"
                     /translation="MKEERKLPEWLIDYAEKEGLIAELKPKHERQNFLVGDDRLDHAV
                     AFLWKDPQTGETVGASYQGTIVDFNRFGKRGTYKHIDKNPTPNHGFNLKIGDPKHLKF
                     FESSIDLLSYAALNREKLQDAWLVSMDGLKHHVISHYVEESISELRRKQTFPQSIEIC
                     VDNDRAGHIFYEKEQMKGIVDPFTNKKIRCERGIPNDWQVPKEYKATYEAVAKEMSVE
                     PEAIMAIHKTETNLQLTNQLVSAHDVQSTFGKMLAKGEPVETIDLKEACTTVAKELKV
                     CERADGTYNFDRFYSRKANIKDVNAGILLSYKAEQYYKGYKKHEHEFVPEVKKDWNDQ
                     LKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            1220..>2733
                     /locus_tag="IVD66_002854"
     CDS             1220..>2733
                     /locus_tag="IVD66_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP6147014.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELDSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIEKVPLDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTV"
BASE COUNT          997 a          485 c          597 g          654 t
ORIGIN      
        1 gattttattc taaagaatga agacaaaaca gaacgagtag aaaatcttca ttttgagaca
       61 gaaaagtaca aagatcaccc cgttgattat caaccactca cagaaaaagg aaggaattat
      121 ctgaaggaag aacgaaaact accagagtgg ctgattgatt atgcagaaaa agaagggttg
      181 attgctgaac taaagccgaa acatgaacgg caaaattttt tagttggaga cgaccgttta
      241 gatcatgcgg ttgctttttt atggaaagat ccacagacag gagagacagt aggggcaagt
      301 tatcaaggaa cgatcgtcga ttttaatcgt ttcggtaaac ggggaacgta taaacacatt
      361 gacaagaatc ctacgccaaa tcacggattt aatttaaaaa taggcgatcc gaagcattta
      421 aaattctttg aaagtagtat tgatctgtta agttacgctg cattgaatcg ggagaaacta
      481 caagatgcct ggttagtttc gatggacggg ttaaaacatc atgtaatcag tcattacgtt
      541 gaagagtcga tttctgaatt aagacgaaaa caaacatttc ctcaatcgat tgaaatatgt
      601 gtggacaatg atcgtgcagg acatattttt tatgaaaaag aacagatgaa gggaatcgtt
      661 gatcctttta ccaataagaa aatccgttgt gagcgaggaa ttccaaatga ttggcaagta
      721 cctaaagaat acaaagctac ttatgaagca gtcgcaaaag aaatgagtgt tgaacctgaa
      781 gcaattatgg ccatacacaa aactgaaact aatttacagc tgacaaatca attggtgtct
      841 gctcatgatg ttcaatctac gtttggaaag atgttggcga agggcgaacc agtagaaaca
      901 attgatttga aagaagcatg taccacggtc gcgaaggaac tgaaagtatg tgaacgcgca
      961 gatggaacat acaactttga tcgtttttat agtagaaaag ccaacataaa agacgttaat
     1021 gcaggaatcc ttctttccta taaagcagaa caatactaca aaggctataa aaagcatgaa
     1081 catgaatttg tacctgaagt gaaaaaggat tggaatgatc aattgaagca tgagatccag
     1141 caacaagaaa tcagaaagca aaaacgtgcg atgttgtttc aacaaggcag acaacaagaa
     1201 agggagtgaa gtcgtcacta tgaaaaccgt cattttagca gaaaaaccgt cacaagcgaa
     1261 ggcttatgcc gatagctttt ctaaagctac ccgaaaagat gggtattttg agatccaaga
     1321 tcgattgttt acaggagaaa ctgtgatcac gtatggtttt ggtcatttag tcgagttaga
     1381 ttcgcccgat atgtacgatg aaaaatggaa acaatgggca ttagaacatt tgcctatttt
     1441 ccccaatcaa taccactatc atgttcctaa agataagaaa aagcagttta gtgtcgtcaa
     1501 acgacagctg cagtcagctg atacgattgt gatcgcgact gatagcgatc gtgaagggga
     1561 gctgattgcc tggtcaatca ttcaacaagc aggcgccaat caaggaaaaa cctttaaaag
     1621 actttggatc aactccttag aaaaagaagc catttatcag ggattccaac agttacgaga
     1681 cgcagaagag acctatccaa aatttgaaga agtacaagca cgtcagatcg ccgattggtt
     1741 aattgggatg aacggtagcc cactgtatag tttactcttg cagcaaaaag gcataccagg
     1801 aagtttttct ttaggtagag tccaaacccc aacactctat atgatttatc aattgcagga
     1861 aaagattaga aacttccaaa aagaaccata ttttgaagga aaagcccaag taatcgctca
     1921 aaatggcgca tttgatgcga agcttgatcc aaatgaaacc caagcgacac aagaagcatt
     1981 tgaagcctat ttaaaagaaa aaggtgttca attaggaaaa cagccaggta cgatccttca
     2041 agtcgaaaca gagaaaaaaa gtgcggctag cccacgtctt ttttctttat cgagccttca
     2101 gtctaaaatg aatcaactca tgaaagctag tgccaaagat actttggaag ccatgcaagg
     2161 gttgtatgaa ggaaaatatc taagctatcc gcgaacggat accccttata ttacggaagg
     2221 ggaatatgcg tatctgttgg atcacttaga cgaatacaag cattttttaa aagccgaagc
     2281 gattccgact cctattcata caccgaatag tcggtatgtg aataataaga aagtccagga
     2341 acattacgcg atcattccta caaaaacggt tatgacagca gcggcttttg aacaactaag
     2401 tccactgcag caggctattt atgaacaagt gttaaaaaca acggtggcca tgtttgcgga
     2461 aaagtatacc tatgaagaaa caacgatctt gacgcaagtt cagcagcttc agttaaaggc
     2521 aatcgaaaag gtgccgctag atctaggttg gaagaagtta tttggaaaag agagcgacgg
     2581 aaaagagaag gaagaagagc cgctacttcc taaagtgaca aaaggagaaa tggtgacggt
     2641 ggatctacaa gttcttgaaa aagaaaccaa gccaccacaa ccttataccg aaggtacgtt
     2701 gatcactgca atgaaaacag ctgggaaaac cgt
//
LOCUS       DACBZK010000166         2731 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.174, whole genome shotgun sequence.
ACCESSION   DACBZK010000166 DACBZK010000000
VERSION     DACBZK010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.174"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            179..775
                     /locus_tag="IVD66_002855"
     CDS             179..775
                     /locus_tag="IVD66_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP6147015.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            899..2698
                     /locus_tag="IVD66_002856"
     CDS             899..2698
                     /locus_tag="IVD66_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAP6147016.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT          776 a          468 c          516 g          971 t
ORIGIN      
        1 tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga gatcaatctt
       61 ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa aatggcgcag
      121 ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt gatgaataat
      181 gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat taggcctatc
      241 aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga atgcgttaag
      301 aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca tccaaatcct
      361 gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg tcctgatatt
      421 tggcccttat gctggattta tctataacta tattggaatc tgcattggtt cgattatcat
      481 ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta gcgataagac
      541 atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc tgtttgctct
      601 agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg gattgacaaa
      661 catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt cgattttctt
      721 atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg gataatattt
      781 attttgtaaa attagtcatt gattgacaat gttaaatctg ggaaagggtc tgcaaaacac
      841 actgcaccct ttcctttttc attagatttg cgctataatg tgaagagcag gtgataggat
      901 gaattatttg aaacgtagct taggtaatgc ttgggacttt ttaaaaggaa cacaagctta
      961 tttccgtgat gtcttgctga tgcatggctt tattttattt atttgtttac ccttattgag
     1021 cagtacgacc cgttttattt tacaccgagg ggcaattgac tatttgtctt atgacaatat
     1081 tccttcaatt ttttctcaac atcctggggt tctactctcg ttaatcgtag ttttgatgac
     1141 gattttactg ttagtttatt tcgaatttac ttttcttttg atgagtgttt tttttattaa
     1201 aaagaaagaa ccaatctctt tgaagcaact cttacacttg acgatacttc agctgaagaa
     1261 agtgagaccc attacttttt tgtttttcct tgcttatttt ttattgattc taccgatcag
     1321 cggattaagt tttaattctg atctactgtc aaaaataaaa atccccgctt tcattatgga
     1381 ttttattttt gctaatcgtt ggatcatcgt cagttccttt ttactcgttt atattttcct
     1441 tggctatatt gggattcgac tgatttttgc tttaccggaa atgattctac gggatcgtcc
     1501 ttttcgagca gccattcggg aaagctggtc attgaccaaa tcgcgtcttt tggccatcac
     1561 gggccaattt attgtgattg gcggtacgat tttactcctt tcttctttag gatatatcgt
     1621 tgttattttg gcacaaagta tggttgaaca atttttccca gactatgcat tgatcagcgc
     1681 tgtgtttgct atgacgcttt tacaagggat tttattattc aatatcgtga tgtctaccgt
     1741 agggattttt tatatcattg ttgatttcat ggatgacgaa ggcttcttgc ctgagatccc
     1801 taagtggttt atcccacaag cccccaactt gcgtttctct gcgctgaaaa acactggttt
     1861 gactcttttt gcagtttttt tcggtattgg cgtctgtctt tacaatatgg attatctgac
     1921 ttcagctgtt cagacaaaac cagtgactgt ctctcacaga ggtgtgagta cccaaaatgg
     1981 ggcgcaaaat actttagaag cacttgaaaa aacaagcaga gactatcatc ctgattatgt
     2041 agagatggat gttcaggaaa caaaagatgg tcatttcgta gtgatgcatg atgcaaatct
     2101 tcgtcactta acaggggtaa atggaacacc acaggatctt acattgaaag aattgacaaa
     2161 tcttacagtt actgaaaacg gagtgcaagc ccctgtttgt tcttttgatt cttatttgga
     2221 aaaagcacat aagctaaacc aaaaattact tattgagatc aagacctcta aaaaagattc
     2281 ggatgacctt gtcgaacgat ttgtccataa ataccgcaaa gttatcttag agaaccatca
     2341 tattttgcaa agtttgacgt accaaaccgt ttcagattta aaagaagcag aaccaaactt
     2401 ttatgtgggc tacatcttac ctttcaatat tgttgggccc cctgtgacgc ctgctgattt
     2461 tctgacaatg gaatatagta cgatcaaccg taacttcatt aattctgccc accaagacgg
     2521 aaaagaagta tatgtatgga caatcaacga ttcagatgct atgagtcgca tgatgtttta
     2581 tggtgtggat ggtatcataa ccgatgagat gggactacta aatgaaagtg tgaaacaaac
     2641 agatgaagaa atcacttatt cagataaact gctaaatttt gttttgggag tcggctaatc
     2701 aaaaatcgtt aatgaaaaaa gtctttatac a
//
LOCUS       DACBZK010000167         2724 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.175, whole genome shotgun sequence.
ACCESSION   DACBZK010000167 DACBZK010000000
VERSION     DACBZK010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2724
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.175"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            178..1200
                     /locus_tag="IVD66_002857"
     CDS             178..1200
                     /locus_tag="IVD66_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAP6147017.1"
                     /translation="MIAELKPKYERQNFLVRDDRLDHAVAFLWKDPQTKETVGASYQG
                     TFIDYERFGERGTYKHIDKNSTANHGFNLKIGDPKQLKFFESSIDLLSYAALNRDQLN
                     DTWLVSMEGLKHHVISHYFGEAVSELRKKQAFPQSIEICVDNDRAGHIFYEKEQLMGA
                     VDPFTNQKVRCERGIANDWQVPKEYKIIYEEVAKEEKVTPEAIMAIHKTENNLQLTNQ
                     LVSAHKVNAFFGQQLSVNDSIEAINLKDICREVAKELKVCERVDGTYDFDRFYQEKGD
                     INAQILFSYKAEQYYKGYKNHEHEFIPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQG
                     RQQERE"
     gene            1211..>2724
                     /locus_tag="IVD66_002858"
     CDS             1211..>2724
                     /locus_tag="IVD66_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP6147018.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAESIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ENDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTV"
BASE COUNT          988 a          494 c          588 g          654 t
ORIGIN      
        1 gattttattc taaagaatga agacaaaaca gaacgagtgg aaaatcttca ttttgaaaca
       61 gaaaagtaca aagatcaccc cgttgattat caaccactca cagaaaaagg aaggaattat
      121 ctgaaggaag aacgaaaact accagagtgg ctgattgatt atgcagaaaa agaagggttg
      181 attgccgaac taaagccaaa atatgaacgg caaaatttct tagttcgaga cgatcgttta
      241 gatcatgcgg tcgccttttt atggaaagat ccacagacaa aagagacagt aggggcgagt
      301 tatcaaggaa cgttcattga ttatgaacgt tttggtgaga gaggcacata taagcatata
      361 gataaaaatt cgacagcgaa tcatggcttt aacctaaaga tcggtgaccc taagcagtta
      421 aaattttttg agagtagtat tgatttactt agctatgctg cactgaatcg tgatcagtta
      481 aacgatacgt ggttagtctc tatggaaggg ttaaaacacc atgtgatcag tcattatttt
      541 ggtgaggcag tatctgaatt gagaaagaaa caagcctttc ctcaatccat cgagatttgt
      601 gtggataatg accgtgcagg acatattttc tacgaaaaag aacaattaat gggcgcagtc
      661 gatccattta cgaatcagaa agtacgttgt gaacgaggaa tcgctaatga ttggcaagtg
      721 ccaaaagaat acaaaatcat ttatgaagaa gtcgcaaaag aagaaaaggt cacaccagaa
      781 gctattatgg ccatacacaa gacagaaaac aatctgcaat taacgaacca actggtttcc
      841 gctcacaaag taaatgcgtt ttttggccag cagctttctg ttaacgattc aatagaagcc
      901 attaatttga aagatatttg tagagaagtc gcaaaagaat taaaagtttg tgaacgcgtg
      961 gatggtacgt acgattttga tcgtttttat caagaaaaag gggatattaa tgcgcagatt
     1021 cttttctctt ataaagcaga acaatactac aaaggctata aaaatcatga acatgaattt
     1081 atacctgaag taaaaaagga ctggaacgat caattgaagc atgagatcca gcaacaagaa
     1141 atcagaaagc aaaaacgtgc catgttgttt caacaaggca gacaacaaga aagggagtga
     1201 aatcgtcatg atgaaaaccg ttattttagc agaaaagccg tcacaagcga aagcttatgc
     1261 cgatagcttc tctaaagcca ctcgaaaaga cgggtatttt gaaatccaag atcgattgtt
     1321 tcctggtgaa actgtgatca cgtatggttt tggtcattta gtcgaattag attcgcccga
     1381 tatgtacgat gaaaattgga aacaatggtc attagaacat ttgcctattt tccctacaca
     1441 ttatcactat catgttccta aagataagaa aaagcaattc aaggtggtga aacagcaact
     1501 tcaatcggcc gacaccatta ttattgcgac agatagcgat cgtgaagggg aactgatcgc
     1561 ttggacgatc attcaacaag taggcgccga tcaaggaaaa acctttaaaa gactttggat
     1621 caactcctta gaaaaagaag ccatttatca gggattccag cagttacgag acgcaaaaga
     1681 gacctatcca aaatttgaag aagcacaagc acgtcagatc gccgattggt taattgggat
     1741 gaacggtagc ccactgtata gtttactctt gcagcaaaaa ggcataccag gaagcttttc
     1801 cttaggcaga gtccaaaccc caacgcttta catgatttat caattgcagg aaaagattag
     1861 aaatttcaag aaagaacctt attttgaagg aaaatccgaa gtaatcgctc aaaatggcgc
     1921 atttgatgcg aagcttgatc cgaatgaaac ccaagcgacg caagaagcat ttgaagatta
     1981 tttaaaagaa aagggggttc aattgggaaa acagccaggc atgattcgcc aagttgaaac
     2041 cgagaaaaaa agcgcggcaa gtccacgtct tttttctcta tccagccttc agtctaaaat
     2101 gaatcagctc atgaaagcta gtgccaaaga cactttggaa gccatgcaag gcttgtatga
     2161 agggaaatat ctaagctatc cacgaacaga caccccttat attacggaag gggagtatgc
     2221 gtatttgttg gatcatttag atgaatacaa gcatttttta aaggccgaat caatcccaac
     2281 ccctattcat acgccgaata gtcggtatgt gaataacaag aaagtccagg aacattacgc
     2341 gatcattcct acaaaaacgg ttatgacagc agcggctttt gaacaactaa gtccactgca
     2401 gcaggccatt tatgaacaag tgttaaaaac aacggtggcc atgtttgcgg aaaaatatac
     2461 ctatgaagaa acaacgatct tgacgcaagt ccagcagctt cagttaaagg caatcggaaa
     2521 agtaccgata gatctaggtt ggaagaagtt atttggcaaa gagaacgacg gaaaagagaa
     2581 ggaagaagag ccgctacttc ctaaagtgac aaaaggagaa atggtgacgg tagatctaca
     2641 agtccttgaa aaagaaacca agccaccaca gccttatacc gaaggtacgt tgatcacggc
     2701 gatgaaaaca gctgggaaaa ccgt
//
LOCUS       DACBZK010000168         2721 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.176, whole genome shotgun sequence.
ACCESSION   DACBZK010000168 DACBZK010000000
VERSION     DACBZK010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2721
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.176"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            101..1273
                     /locus_tag="IVD66_002859"
     CDS             101..1273
                     /locus_tag="IVD66_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015077585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HAP6147019.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
     gene            complement(1403..>2721)
                     /locus_tag="IVD66_002860"
                     /note="aph(2'')-Ia"
     CDS             complement(1403..>2721)
                     /locus_tag="IVD66_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HAP6147020.1"
                     /translation="RTESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTD
                     YHYPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPR
                     AIRAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFK
                     VDSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPN
                     IEYSYISDELSILGYKEIKGLFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDI
                     SECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDF
                     SCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNID
                     IEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          946 a          478 c          343 g          954 t
ORIGIN      
        1 ataaagtccg tataattgtg taaaagtaaa aaggccatat aacagtcctt ttacggtaca
       61 atgtttttaa cgacaaaaac atacccagga ggacttttac atgacccaag tacattttac
      121 actgaaaagc gaagagattc aaagcattat tgaatattct gtaaaggatg acgtttctaa
      181 aaatatttta acaacggtat ttaatcaact aatggaaaat caacgaacag aatatattca
      241 agcaaaagaa tatgaacgaa cagaaaaccg acaaagtcaa cgaaatggct attatgagcg
      301 cagctttacg acacgtgtag gcacgctaga attaaaagta cccagaacac gtgatggcca
      361 tttttcaccc acagtgtttg aacgttatca acgaaacgaa aaagccctca tggcttcaat
      421 gttggaaatg tatgtatcag gcgtttcaac tcgtaaagta tcaaaaattg tggaagaact
      481 ttgtggtaaa tccgtctcta agtccttcgt ttctagctta acagaacagc tagaacctat
      541 ggttaacgag tggcagaatc gtttattatc agaaaaaaat tatccttact taatgaccga
      601 tgtactctat ataaaagtac gagaagaaaa tcgagtactc tcaaaaagct gtcatatagc
      661 gattggaata accaaagatg gcgaccgtga aattatcggc ttcatgattc aaagtggcga
      721 aagcgaagag acctggacaa cattttttga atacctaaaa gaacgcggtt tacaaggtac
      781 ggaactcgtt atttctgatg cgcacaaagg attagtctct gccattagaa aatccttcac
      841 caacgtaagt tggcaaagat gccaagttca cttcctaaga aatatcttta ccaccattcc
      901 taaaaaaaat tcaaaatctt tcagagaagc tgttaaagga atttttaagt tcacagatat
      961 taacttagcg cgtgaggcta aaaatcgatt gattcatgat tatatcgatc aaccaaaata
     1021 ttcaaaagct tgcgcatcat tggatgatgg attcgaagac gcctttcaat ataccgtaca
     1081 aggaaattcc cacaatcgac taaagagtac caatctaatt gaacgactga atcaagaagt
     1141 acgcagaaga gaaaagatta ttcgcatctt ccccaatcaa acatcagcca atcgcttaat
     1201 tggagccgtt cttatggacc tacatgatga atggatttat tcttcaagaa aatacatcaa
     1261 ttttgataag tagaaatggt aaaaacattg tatagcattt tacacaggag tctggacttg
     1321 actcacttcc tttattattt ttcatttttt taaactattt aatactaatg tcttttataa
     1381 tagcttttca tatattatat aatcaatctt tataagtcct tttataaatt tcttttctac
     1441 cattttcgat aaattcctgt ttaatatttt taattccata aacaatagtt tcaataggat
     1501 aatattcttc aactatatct tgatattctt ttgctttctc aatatctata tttccataca
     1561 ttcttaatat atcttctcca aaatttgttc ctatttcttc ttcactatct tcaagtaagt
     1621 atataaaatc acaatattca tctataattc cagaatctcc aaaatcaatt attccagtta
     1681 atctattatt gccatctaac aatagatgat tacaactaaa atcattatgg cataaacact
     1741 ttttaccctc aaaaactgtt gttgcattta gtctttccat aaaactttct atataatctt
     1801 tttctatatc agttaaatca ttataaatag tttcacgcaa caatatatac tcttctaata
     1861 cattttgttt attatcaata gtacattcac taatatctgt ataatctaaa ccgtgcattt
     1921 gtcttaaaaa actggcaata tctcgtttta acaaattttg ttcttcttct gacatagtag
     1981 aataaatttc tggtgttaaa aaaagtcctt taatttcttt ataacctagt atagataatt
     2041 catcactaat atacgaatat tcaatattag gaatttttac attagtttct aaatttgtat
     2101 ttaaaaaatt atatattgct ttttcttttg cataaccttt tttcttatta gtactaaatt
     2161 ttgttttaaa aatgtattca ttattaacta aatatgccac actatcataa ccactaccga
     2221 ttatttcaat actatctact ttgaaattat caaagtaatg ctcaattaaa tatttcattg
     2281 ccttaacatt tgtggcatta tcatcatatc tatattccat taaataacaa tcttcttttt
     2341 tgccctcgtg taattcatgt tctggcaaat cttcaataat tctaaaacca gatttttggt
     2401 atgcccttat tgctcttgga ttatttttat gagggtctaa aataactgca ttagcatttc
     2461 tttctttttt caaaaattca aaaatcaatt taatatatct tgtaccaatt cctttactcc
     2521 aataatttgg ctctcctata aattgatcca taccatagac tatctcatca gtttttggat
     2581 aatgataatc agtatataac tcatcataca ttttatatat ttgtccatat ccaataggaa
     2641 cattgttata ttcaataatt actctaaaaa cttcatcttc ccaaggctct gtataatgtt
     2701 tttttaatga ttcggttctg t
//
LOCUS       DACBZK010000169         2652 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.177, whole genome shotgun sequence.
ACCESSION   DACBZK010000169 DACBZK010000000
VERSION     DACBZK010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.177"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            137..748
                     /locus_tag="IVD66_002861"
     CDS             137..748
                     /locus_tag="IVD66_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAP6147021.1"
                     /translation="MYFILPTLYSLLCVMAPCIIYMVFFCKKNTLKHNILILIFMLYC
                     WKVFELTGTGGLTDIFYRPDTGRKFSLVQGSVNLVPFSGLNISFILNIVMCVPLGFLL
                     PIIWKSYRKIVPVFLAGALFSLIIEVSQIITTRATDIDDLIANTFGAVIGFILWAVLS
                     RVVSLKDKSSTVDYLEPYIYILIGFTGKFLLYFPFWFAFEVLS"
     gene            821..1750
                     /locus_tag="IVD66_002862"
     CDS             821..1750
                     /locus_tag="IVD66_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAP6147022.1"
                     /translation="MKRFLKWGLVLLASLIVILMCTAVVISYVNRPYARAVYDRIKRI
                     LDKDFYDHLYLGSSFEIINLDTMDIHSYMKKDQEELPASLSKLFTIDYALSVLSLDEQ
                     ITISPTALDMQKADSSTAHLQEGDILSVYDIICAMVLPSGNDAAYSLAIYTGGKLDPD
                     AKNDEERYQSFMKNLDRYLSEQGYKHTHFTDAAGYDSNATTSAEDLTKVAAKLLKNDK
                     FAEIVAKETYRAKSIKGNVYNWNTTNQFMQQDNRYFTEGVKGVKTGSFDGRYNLCVYY
                     TSSSDNHYLLVSFGSESDSRRYVDVQNLLHNLP"
     gene            1908..2645
                     /locus_tag="IVD66_002863"
     CDS             1908..2645
                     /locus_tag="IVD66_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HAP6147023.1"
                     /translation="MLISCGARLAPFDIRELRELMSEDELELDKIGDRKTALFVIISD
                     TDDTFNFVVSIMYSQLFNLLCDKADDVYGGRLPVHVRCLLDEFANIGLIPKFEKLIAT
                     IRSREISASIILQAQSQLKAIYKDHADTIVGNCDSTLFLGGKEKTTVKELSETLGKET
                     IDLYNTSETRSNQKSFGLNYQKTGKELMSQDEITVMDGGKCIYQLRGARPFLSDKFDI
                     TKHKNYKLLEDYDKKNLFDVEEYLKQR"
BASE COUNT          930 a          369 c          493 g          860 t
ORIGIN      
        1 cctctaggaa aaaattaact agcaccacgg gttatgatat aataaaatgt attataggca
       61 tttttttaca agaaatagaa gcttgaagtt tatatgaagt tataaaattt aatttatatt
      121 ggaaggagga aaataaatgt attttatact acctacactt tatagccttt tatgtgtaat
      181 ggcaccatgt attatttata tggtattttt ttgcaaaaaa aataccctga aacacaatat
      241 cctgattttg atttttatgc tgtactgttg gaaagttttt gaattgactg gtacaggtgg
      301 actaacagat attttttata gacctgatac aggtaggaaa ttttctctag tacagggcag
      361 tgttaatctt gtaccattca gtggactaaa cattagcttt atattaaata tagtaatgtg
      421 tgtgccctta ggattcttac taccaatcat atggaaaagt tataggaaaa tagttcctgt
      481 tttcttggct ggggctctat tttcactaat tattgaagtc tcacaaatta taactacaag
      541 agcaacagat attgatgatt taatagcaaa tacctttggt gcggttatag gctttatact
      601 gtgggctgtt ttaagtagag tggtgtcctt gaaggacaag tcatctacag tagattattt
      661 agaaccttat atttatatat tgattggttt taccggaaaa ttcttactgt attttccttt
      721 ctggtttgct tttgaagtat tatcctgata attccataga aaataatgag tttgagttga
      781 gaaagaatat tcttgtacac aactctggaa aggaggaagt atgaaaagat tcttaaaatg
      841 ggggcttgtt cttttagcgt ctttgattgt gattctaatg tgtacagcgg ttgttatttc
      901 ttatgtgaat cggccgtatg caagagctgt ttatgatagg attaaacgca ttcttgacaa
      961 agatttttat gaccatctat atctaggttc ttcatttgaa ataataaacc ttgatacaat
     1021 ggatattcat agctatatga aaaaagacca agaagaatta cccgcctcat tgagcaaatt
     1081 atttacgatt gattatgcgc ttagtgtcct aagtttagat gaacagatta caattagtcc
     1141 tactgcactt gacatgcaga aagctgactc atctactgca catcttcaag aaggagatat
     1201 tttatctgtt tatgacatta tctgtgctat ggtcttaccc tcaggaaatg atgcagctta
     1261 tagtttggca atttatacag gtggaaaact tgatcctgat gcaaagaatg atgaagaacg
     1321 ctatcaaagc ttcatgaaaa acttagatcg ttatctaagt gagcaaggct ataaacatac
     1381 tcattttact gacgctgctg gctatgactc caatgctaca acatcagcgg aagatttgac
     1441 aaaagtagct gcaaagctac taaagaatga taaatttgca gaaatagttg ccaaggaaac
     1501 ttatagagca aaatcaatta agggaaatgt ttataactgg aatactacga atcaatttat
     1561 gcaacaagat aatagatact ttactgaagg tgtaaaaggt gtaaaaactg gatcgtttga
     1621 tgggagatac aatctatgtg tgtattatac atctagttct gataaccact atttacttgt
     1681 aagttttggt tcagagagtg atagtaggcg ttatgtagat gttcaaaatc tattgcataa
     1741 tctgccttga aatttcgtgc ctttaagcgc gtatctaaag tttctttgaa aagtttgaga
     1801 atgaagaaag tgagcagtcg aaaaacggtt gctcactttt ttgccctaaa atcgaaaaaa
     1861 tataaaaaag tcctttacaa cacgtctcag gaaaaactgc taagtcaatt ctaatatctt
     1921 gtggagcaag acttgcacct tttgatataa gagagcttag agaactaatg agcgaagatg
     1981 aactagaact cgataaaatt ggagatagaa aaactgcctt gtttgtaata atatcagata
     2041 cagatgatac atttaatttt gtagtttcaa taatgtattc tcaattattt aatctactat
     2101 gtgataaggc agatgatgtg tatggtggaa gacttccagt tcatgttagg tgtctacttg
     2161 atgagtttgc aaatatcggt ttgattccta aatttgaaaa actaatagcg acaattcgtt
     2221 caagagaaat atcggcaagt ataatactgc aagcacaatc tcaattaaaa gcaatttata
     2281 aagaccatgc agatacaata gttggtaact gtgactctac actttttcta ggaggaaaag
     2341 aaaaaacaac agtaaaagaa ttatcagaaa ccttaggaaa agaaaccata gacctatata
     2401 acacatcaga aacaagatca aatcaaaaat cttttggtct aaattatcaa aagactggca
     2461 aggaacttat gagtcaagat gaaataactg taatggatgg tggtaagtgt atttaccagc
     2521 taagaggagc aagacctttt ctatctgata aatttgatat tacaaagcat aagaattaca
     2581 aattgttgga agattatgat aagaaaaact tgtttgatgt agaagagtat ttaaaacaaa
     2641 gatagcgtaa aa
//
LOCUS       DACBZK010000170         2636 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.178, whole genome shotgun sequence.
ACCESSION   DACBZK010000170 DACBZK010000000
VERSION     DACBZK010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.178"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            106..1305
                     /locus_tag="IVD66_002864"
     CDS             106..1305
                     /locus_tag="IVD66_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAP6147024.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(1332..2600)
                     /locus_tag="IVD66_002865"
     CDS             complement(1332..2600)
                     /locus_tag="IVD66_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HAP6147025.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
BASE COUNT          789 a          573 c          468 g          806 t
ORIGIN      
        1 aaaacatctt tccatcggaa agatgttttt ttgctttttc tagtttaaat aacagctttt
       61 ttcatctatt ttcgttatac tgtataagaa aaaggagttg aatttatgaa tctaaccaga
      121 gatctgatct ttttagttct ctatcttatt ggggtattct ctatcgttta ttggcgaaaa
      181 cagaagaagg atccttcctt gttcttttac ggcagtacgt ggacatttac ggtaatctta
      241 acttattttg tcgtgttgga aattttttat tcgacctttt attttttgat tccattgttg
      301 ttctttagta tctttgcttt ttcttatttc acagaaaaac gaaggctact gaatggtctt
      361 ttattcaatg ttttactcat cagtttcggc atctacttgt ttgtcttgct gtatgaaacg
      421 caaaatattt ttcttggcgg actgatcgcc ttgatcacga ttccattgct acttgtcctt
      481 ttatttggta tttatggatt gattgttttt cttttttgga acggggtcac agttttacgt
      541 agagaatcgc attcattagc taatctttta acgttgatac tagccatttt tcttacactg
      601 tttcttgttt ttgacttttt cttgttaaaa tatttgccgc aatggataaa tgctttgttt
      661 ttctgcgttc ccctgatctt gatctatcta tttatcgtat tctacaactt tttgactgtc
      721 tcattcttgt atcagttcaa ccggcctcga tacaatcaag acttcatcgt tgtgttaggc
      781 gctggattga tcaatggaga aacagtttct cctcttctag ccaagcgaat caataaggca
      841 attgcttttt atcgggctca aagccgtgct acattaaatc cgcccatctt attgatgtct
      901 ggcgggcaag gagcagacga aaaagtacca gaggccattg cgatgaaaca atatgccatg
      961 gaacaaggaa tccctgaaag agacattctt gtcgaaacca attcgacaac cactttggaa
     1021 aacatgctct attcaaagga aatcatggat cagcaaatga aagggccata ccgcgcgatc
     1081 tttagttcca acaattacca catttttaga gccggtcttt atgcgcggca agccaaattg
     1141 aaagcaaatg gtattggtgc aaaaacagct ttctactact tgcctaatgc gtttttaaga
     1201 gaatacctcg ccatcttgat gatgaacaaa aaaagacata tgatcatttg cggattgctt
     1261 ttcgcaggct ccgcattctt atcgctgatt actttacttt tctaaaaaaa caaggtgtga
     1321 caaaacatat gtcacacctt gtttttttct ttcattctct taactattgg caaaaagagt
     1381 atcccttttt tgaccgctac ttgctgagca gaataaatac cgctgttgcc tgaacacata
     1441 aagctgatca agcagatcat aaagaagtat actgccgctt gtgaaccgaa caattcgatc
     1501 cccatcacaa agcaggcaat cggtgtattt gtcgcaccag aaaatactcc gataaagccc
     1561 aatcctgcaa gaaaaggaac agaaacatgg agcaaaggcg ctagtgctgc accaagcgtt
     1621 gcaccaattt caaacaatgg tgtcacttct cccccttgat atcccgcgcc taaagacaaa
     1681 actgtgaaga ataacttccc aataaaatca tagacatgtg cctgtccatt aaatgattct
     1741 tgaagtaacg gaagactcaa tccgagataa cgttgtgttt gcaaaatcaa tgctgctgcc
     1801 acaactacag ctccacctat cgtatttcga caaacaggat gaggaatcca ttgtgcatat
     1861 cgcgctttta aaaagacgat cgaacggctg aatacccaac caatcaaacc aaaagcaatc
     1921 ccagcaacaa aaactttgaa gaacagcaac atactccatt caggaatcac acccatttgg
     1981 taatgtagat gagaaacacc atagctttct gtcatgaaat ttgcaaacag tgcagcaaag
     2041 aagctaggga agatcgcttc tgttcggact ttcccgattg ccaacacttc taatccaaat
     2101 aatgttccag ctaaaggtgt gccaaataca gaactaaaac ccgcactgat tccactgata
     2161 atcaagattt cccgttctga tttatccaat cggaacaaac gtgccgtatt atctgctaac
     2221 gctcccccca tttggactgc tgttccttca cggccaacag atcccccaaa taaatgggta
     2281 gttatggttc caaacagtgt aagtggaata agccgcaacg ggattttttc ttctccacca
     2341 tttccttgat cgatcactaa gttgtttcca cgactagaaa gtccgccgtg atacgcatag
     2401 agataagcaa aaagcgcacc actaactggt agtagacaaa ggagccaagg atgtgatagt
     2461 cggatatctg tcacaactgt caggctattt aagaaaaaag cagacaagct ccccatgaat
     2521 ataccgagaa tcgctgtgat caccagccac ttcagcatat acactaaaat gcgtactgga
     2581 ctcggtaatt gtttttccat aaaaaattcc tcctcaataa aaaaacgcct actaaa
//
LOCUS       DACBZK010000171         2483 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.179, whole genome shotgun sequence.
ACCESSION   DACBZK010000171 DACBZK010000000
VERSION     DACBZK010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.179"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(1014..1304)
                     /locus_tag="IVD66_002866"
     CDS             complement(1014..1304)
                     /locus_tag="IVD66_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147026.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1512..2203)
                     /locus_tag="IVD66_002867"
                     /pseudo
     CDS             complement(1512..2203)
                     /locus_tag="IVD66_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
BASE COUNT          734 a          458 c          348 g          943 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattac tgttgcttct ttactaattt aggtttactt
     1501 gttaagaaag attatttacg caaatgttct tcaacaattt gctgagattt atcagctgta
     1561 tcttccactt catcttttgc tttttctaac ttttgaatat attgtttcaa gcttgagttt
     1621 tcagcagttg cttcgtctaa tttcttttgt gtatctgtta actgatttct acatttgttt
     1681 tttcttgtgt cagtgttgcg atttgttgat tcaaaccatt tacagtattt tgtaattctg
     1741 aaagttttgc ttgtgcttct tgtagtcttg ctgtccaatc tgcattcaga tgattgattt
     1801 catcattttt ttggttgatc tcatctagtt tgacattgat ttcattttgt ttgctttgta
     1861 gttgtgcatc cttgctgact aattgacttt ctaagttttg tttttctgct gccgattgat
     1921 ttttttggtt ttctaattca tttacttttg tttggtattc ttggacatct gcctttgaat
     1981 cttgcaatgt ctgttctttt tgtgctagtc gagcggtaag atctgtaatc gcttgctctt
     2041 tatctgtcaa tgtatgatca agctgtgtca gattctcatt gattgtatca atatctgtct
     2101 ctccacccca caaaataatt tcatttgcgt accgcgtgcc tgtgtagcca attagacata
     2161 gaaatgcaac gacaatccca ccagtaataa atttcttttt catttgcata gctccttaat
     2221 ccaatacttt tacatgctaa aagtaagtga tctcaaacac aatgtcaagc gtttttaaat
     2281 tacatatgta attttaatat aaatactatc aaatactcat ttaatcctcc ttttttatct
     2341 atttaaaaaa tcttttttat agagaaaaat gcaggttaat actttcttaa ataaatattt
     2401 atggtgaaca aaaacaaaaa agcaagtttt attaaacgta acccttttca tttcatagat
     2461 tactgtattt attacaaaaa acg
//
LOCUS       DACBZK010000172         2438 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.180, whole genome shotgun sequence.
ACCESSION   DACBZK010000172 DACBZK010000000
VERSION     DACBZK010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.180"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            2..1147
                     /locus_tag="IVD66_002868"
     CDS             2..1147
                     /locus_tag="IVD66_002868"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HAP6147027.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            1318..1776
                     /locus_tag="IVD66_002869"
     CDS             1318..1776
                     /locus_tag="IVD66_002869"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HAP6147028.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1935..2405
                     /locus_tag="IVD66_002870"
     CDS             1935..2405
                     /locus_tag="IVD66_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HAP6147029.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
BASE COUNT          818 a          456 c          457 g          707 t
ORIGIN      
        1 catgcacatt caaacaaaat tgatccacgg aggcatcagt gaagatccca caacaggagc
       61 tgtcagtgta cctatttatc aaacatccac ttatcggcaa gatggcgtcg gccagcctaa
      121 acaatatgaa tattcaagat ctggtaatcc tactcgtttt gcattggaag aactgattgc
      181 tgatttggaa ggcggtgttc gaggattcgc tttttcttct ggtctttctg ggattcatgc
      241 cgttttttct ctttttcaag ctggcgatca tatcttatta ggagatgatg tctatggagg
      301 aacattccgt ctatttgaca aagttcttac taaaaatggt ctcgagtaca cgatcataga
      361 tacgagtaat cttgataaaa tagaacaatc catcaaaccc aatacaaaag cactttatct
      421 tgaaacacct agcaatccgc ttctaaagat tactgattta gaaaaaagtg ccactctggc
      481 tcatcaacat ggattgatag ttattgctga caatacattt gctactcctt attttcaaag
      541 acctttagat ctcggttctg atatcgttgt ccatagcggt accaaatatc taggcggaca
      601 cagcgatgta gtagctggtt tagtgacttc taaccataaa gatctagccg atcagatcgg
      661 attttaccaa aatgctatcg gagccgtact tggtccccaa gatagctggt tacttcagcg
      721 cggaatcaag acactaagtg ttcgtatgga ggaacatcaa aaaaatgctt ttgtggtagc
      781 tgattttcta ttttctcatc cagcagtaga aaaggtctac tatccaggat tacccgatca
      841 tgaactccat ggagttgcta agcagcagat gagcggcttt agcggaatga tttcttttac
      901 tttaaaaaat gaagaatctg ctattccatt tgttgaatca ctccaactat ttactttagc
      961 agaaagttta ggtggcgtag aaagtttagt ggaaattcct tctgtcatga ctcatgcgtc
     1021 tattccaaaa gaaaaacgag aagaggctgg cataaaggac ggcttgatcc gtctttctgt
     1081 aggaattgag tatggtcagg atctcataaa cgatttagct caggcatttg acagaatcaa
     1141 gaactagaag tcccaataaa cgacttagca gaaaaatcta aaaaatattt cagattgcta
     1201 caccttggaa acgataagtg ttagaatcaa gtagaaagac gtttttgtaa atttcactaa
     1261 ataattcttt agtgaaaagc atcaaaacga atgaacaaac agataggagt cttacaaatg
     1321 agaatgaatg tcgaaagttt taatcttgac catacaaaag tcaaagcacc ttatgtacgt
     1381 gtagctgatc gaaaaacggg tgcgcatggc gatgtcatca ttaaatacga cgtccgcttt
     1441 aaacaaccaa ataaagaaca catggacatg ccaagtctac attcacttga gcacttgact
     1501 gccgaactaa tccgcaatca cgcagattac atcgtagact ggtctccaat gggatgccaa
     1561 acaggctttt acttgactgt attgaatcat gaaagctacg aagacatttt agatgttctt
     1621 gaagcaacaa tgaaagatgt tcttgaagct actgaagtac ctgcaagcaa tgaaacacaa
     1681 tgtggctggg ctgccagcca tacactagaa ggtgcacaag ctttggctcg tgaattttta
     1741 gcaaaacgcg atgaatggtc tgaagtagaa gcatagtttc taaaagaacg taaagatgag
     1801 aagcaatata gctatcttat cttcgtattt tattaaatat ttattgtctg aaaagagttc
     1861 taaacgggaa aacaaatagc tagttttcag tttagcgctc tttttattat ataaaataga
     1921 aaggagaaaa ctttatgtct atttataatt ttgaaactac tttagaagac ggcactgtct
     1981 attcattgaa aaaatatgca ggcaaaccga taatcattgt taacactgca acaaaatgcg
     2041 gtctagcacc tcaatttaaa caattagaag aactttacca agcttatcag acacaaggtc
     2101 tggttatctt aggctttcct tccaatcaat ttaaacaaga gctagattca gcgactgaag
     2161 cagcagaagc ttgtaaaacc acttatggcg ttaccttccc tatgcatcaa ttgattgacg
     2221 taaatggaga aaatacagat cctcttttta cttatcttaa aaatgaagct cctggtactg
     2281 tcactaaagc aataaaatgg aattttacta aatttttgat tgatagaaat ggcaaagtaa
     2341 tcgaacgatt tgcaccacaa acttctccat tgaaaatgac cgctgcaatt gaatccgttc
     2401 tttaacttaa taaaaataaa aaaagatgaa ctatttct
//
LOCUS       DACBZK010000173         2406 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.181, whole genome shotgun sequence.
ACCESSION   DACBZK010000173 DACBZK010000000
VERSION     DACBZK010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.181"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..103)
                     /locus_tag="IVD66_002871"
     CDS             complement(<1..103)
                     /locus_tag="IVD66_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAP6147030.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQEL"
     gene            complement(177..458)
                     /locus_tag="IVD66_002872"
                     /pseudo
     CDS             complement(177..458)
                     /locus_tag="IVD66_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            920..2302
                     /locus_tag="IVD66_002873"
                     /pseudo
     CDS             920..2302
                     /locus_tag="IVD66_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          875 a          412 c          400 g          719 t
ORIGIN      
        1 acaattcctg aacttcacga tagcttagat tgtaacgcag gtagtaacca acagcgacaa
       61 taatgacgtc ttttttgaat tgtttgcctt taaaatgatt cattactctg tcctctctgt
      121 cttttttctc aattttacac taaaatagat tttttggaaa actttgcaac agaaccgaaa
      181 tgagtatagt atgaattagt aatttggttt tcatctaagt ttagctttga tttactaaaa
      241 ttgatatctc gatacatgtt caatacatct aatacaaatc gagaatcttc tttcggaaat
      301 ggctcagaaa gatcactcca aatttcatca tcataatgat actcgtaacc ttctctcaat
      361 atttcgattt ttctttcata ataagatctg ttttggtcct caaatttagc caataactca
      421 aattgattta ctagtgacaa tctctgaaaa ctgtccatta aatgtttctt cctatcttgt
      481 tcattaacaa aaaattataa gcccttacaa cgaatattat atattaaatt taattgtagg
      541 tgaacacgaa ttttataaat atttatggtg ttaatgacaa atgatatccg actcctcttc
      601 atacgttctg gactatttgc taatagatta aaatttcagc atctatttct gaccataaat
      661 aaatgagctg ccgaaaagct gccaaatcag acttgaaaat aaaggatcaa aaacttttaa
      721 gtttctgacc ccgtaactca cacttcaaaa tcttacttaa aaaggagtct gaaagaaaaa
      781 aagagtattc aaaatttttt tctaactagc tacatcacat ctatgcattg acactcaaag
      841 aaccagaata agtcatcaga aagcaagggg gtgcggacat aatcctggac gaaaaaataa
      901 acttaggagg aatgtccgtg tgttttccca caaagagcgt gtaagggcaa ttcagttatt
      961 tttaaaatac gattgctctt atgctgcaac cattcgagaa ttagggtatc cgtcgattgg
     1021 tgcactacgg aaatggtata aagagtattt ggaatccgga gagctccatc aggagcaccg
     1081 aaaaaaatca aagtattctg aagaacaaaa acgaatagcg gtgaatcatt attttgaata
     1141 tggtcaatgt tatgcacgaa ccattcgcat gcttggttat cctaatagag agtccttgcg
     1201 gcagcggtgt gaagaacttg caccaggagc tagaaaactc cgaaaaagtg cggtaaagtt
     1261 aacacaagat caaaaagaag ctgtgttgaa aaaattctat aaaccgcaaa ctaataggaa
     1321 aaatttagcc gaatctggag gaattagtag agttactcta tatcaatgga aaaacacggt
     1381 tcttggaaag gattttccat tgtgtatgac tttaaaaaat caggaaaaac aaaaagagct
     1441 acttttaaag gaagtagaag acttacaaaa acaagtacac caattacagc tcgaaaaagc
     1501 attactcgaa ggagcggctg aactgctaaa aaaagaaaaa ggcgtcaatc ttctttgtct
     1561 atcaaatcaa gaaaaaacga tattgattga tgccttacga aatcagttca ccttgaaaga
     1621 gcttcttcaa cagctccagt ttcctaaaag cagctatttt tatcaaaaac aagcacttga
     1681 gaaaccagat aagtattaca aagaacgtca aattaattat cacgattttc aatcataact
     1741 tctgtgcgta tggttaccgt agaattcacc aagctttaaa aaatatgggt aaaaagcttt
     1801 ctgaaaaagt tgtacgtaga ttgatgactg aggaaaatct atttgttaaa ttttctagac
     1861 gaaaaaagta ttcttcgtat gctggggaaa tttctcctgc acaccccaat ttattaaatc
     1921 ggaattttaa agcaaagaag ccaaatgaaa aatggttaac agatattact gaatttagaa
     1981 ttctcgcagg gaaaatctac ttatcaccac ttgtcgattg ttacgatggt gctattgtta
     2041 gttggactat tggaacaaag ccaacttgct tcactctatg tctaaaaaga gttattcacc
     2101 agataattca gcgtgcgaag gtttctttgg acgattaaaa aacgagatgt tttatcaacg
     2161 tgactggaag aatacaacaa tcaatcagtt tataaacaaa ttggatgatt atattcattg
     2221 gtataataat caacgaatta agttatcttt aggaaggcta agccctcttc aatatcggaa
     2281 gaagcaaaga tatatttgtt aaaaaggtcc aaaaaaaata tccgcacccc cttttttttg
     2341 taaaaaacta ttgcacaata caagtagcct acggctatcg aaatttccat aactttcgag
     2401 caagaa
//
LOCUS       DACBZK010000174         2397 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.182, whole genome shotgun sequence.
ACCESSION   DACBZK010000174 DACBZK010000000
VERSION     DACBZK010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2397
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.182"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            206..2068
                     /locus_tag="IVD66_002874"
     CDS             206..2068
                     /locus_tag="IVD66_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6147031.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2068..>2397
                     /locus_tag="IVD66_002875"
     CDS             2068..>2397
                     /locus_tag="IVD66_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6147032.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          864 a          353 c          466 g          714 t
ORIGIN      
        1 aaaatttgaa aaagcgtttg attatttata ttacgactta gtgcaataaa aaacgctttt
       61 taacagtaca tgtagtcgtc tttataatag ataaactctg taatattagt taaaaagcta
      121 taagttgcac ttagttaagt gcaaacattt catattgtcg ttagtttaga aaacgcttat
      181 attagcaatg taaggagaga tgataatgca gcagctaaca aaaagagaaa ggcagctttt
      241 gatttacttg gtggaaatgt ctgaaccggt aacaatcaaa aagttggctg aaaaagaaaa
      301 tgttagtgtt cggacgataa aatacgatct agatgatata agagagtggc tgaatgagcg
      361 gaagcaagtc ctatatagca aacgtagtca gggaatttgg atgaatatta gtagctctga
      421 tcgaatcaaa ttaaaaagcg aattgatgga tgttaatcgt tttgaaatat ttgcagatca
      481 aagtctccga atcaaacgtt tactaattat gcttttagta acaaaagaag ctattactgg
      541 aatgaaaatg gccaacgcat tagatgtcag caaagatacg atcatgaatg atttagatgt
      601 gctggaaaat aattttctta aggaaggatt gaccttgaat cgtcaggcgc gaaagggttt
      661 ttggatcata ggagaagaac gtctagttcg attaacgatt gaagagattc ttcaaaaaga
      721 gttcacggat tatgacattt ataaattaat gtcattgtta ttgaatggcg gtgagactga
      781 atactttgaa atgtattctg ctactgctac acctatccaa gaggtattta atcaagtaat
      841 cattcgaatg cgacacttac tggaatttga aaatctagag aaactgaatt acgcggaatt
      901 actaaatatt ctgattcgag tgacaattgc taccgttcgc ttacgcaaag aggctacgat
      961 tggtcgttat caattggttg ctgaacaaga attagacaaa aacgatcttt cttatcgcgt
     1021 catgcagcag gtctttgatt attatcagtt gccactgttc gaggatgaat atcattatat
     1081 ctatagtgat acattcgaca cgattcacca gcaagacgtc atgaaactag ttgagaatgt
     1141 gatttataaa gtaagtaaag caatcaacca ttctttttat caagatccac aattgttgac
     1201 gaatctgtat gctcatttat ccatgcgatt atcgagaaag aaaaaatttg tcaatgaata
     1261 taatcctttt aaagaagata tcaagcagaa atacccggaa ttatttgatg cgatcaagca
     1321 agcagttcga caagaaataa gtgaacaaaa tattctgatc aatgattctt tcgtggcata
     1381 tattgcctta cactttttgg tttcctacga aagagaagaa gatctacgaa gcgttagagc
     1441 cgtctacatt tgttcaacag ggttgggtgt gactagtctg atcaagcaaa agatcaatga
     1501 agaattaaat aatatcacta tcgtggcatt tgcttcagta ttgaatgcgc aagaaatgat
     1561 tgctaccaaa gatcctgatt tggtgattag tatttttcca attaatggca tcgatcgtcc
     1621 tttcatcaaa gtccatccat tacccactga acaggacttg aaaaaaattc aacaaataat
     1681 aaaaaaaata cttgcttctt ccaatcagca ggaaaggcat aacttgaatc ttagagaaac
     1741 gtccatcaat aaagatactt tagaagactt tagcaaggaa ttgattttga aagcttatac
     1801 gatttatgaa cgtttacttg tcattttgga agcagaattg atccaagaat atcgagaagc
     1861 ttttttgctt catgtattct taatggttca tcgtatcaca tttgatcaac aatatatggc
     1921 agaaggtcgt caagtagacc agattatttt agacaaagga acactggtag gaaaaatcga
     1981 agcagttttt gcagaaaata atttaggaat caatcagtca gaaatcagtg cattattctc
     2041 atatataaaa gaaggagcgt caagttagtg aaaatgtcag acgaggcttt aaaaattatc
     2101 gaggaaagtc aaaatcggga aaagttaaaa caagtgattg atctaattga agagcgatta
     2161 gtagaacatg ctattgtacc aaccgagttg cagtggacca ttctaattaa tcacttgaat
     2221 gagatgctga aacgttctca aagaaaggaa acgattcccg tagtcgatcg ggatttgttc
     2281 aaagaagtat ccaaagaagc cataactatt tctgatgaaa tagttagaag tatcggtaat
     2341 ttaaccgatg atgaaatata tgttttgtcg attcattttg aaacagcaaa aaataat
//
LOCUS       DACBZK010000175         2395 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.183, whole genome shotgun sequence.
ACCESSION   DACBZK010000175 DACBZK010000000
VERSION     DACBZK010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.183"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            316..570
                     /locus_tag="IVD66_002876"
     CDS             316..570
                     /locus_tag="IVD66_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP6147033.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            571..888
                     /locus_tag="IVD66_002877"
     CDS             571..888
                     /locus_tag="IVD66_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP6147034.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1447..2382
                     /locus_tag="IVD66_002878"
     CDS             1447..2382
                     /locus_tag="IVD66_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147035.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          861 a          339 c          453 g          742 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaatggatgt taacggaagt gtatggtgag tagttcactc gtattttgat atcgtttgta
      181 tatgttttca gcgttctaag tggcttattt tgtccaataa taatatggag tggaatccct
      241 taagaaacac cgttggcaat tgttgttata acatgttata atttattcat caaaaactaa
      301 aaggagtgtg ataacatggg aaaagaacta aaggttagaa agatcggcaa tagcgtggga
      361 gtgatccttc caagctctct tggattaaaa agcggagaca ttatccaagc caaacaagaa
      421 ggcaacttat tcatattaga tactactcaa atagcaaaag aacacgatcg caaattgatt
      481 gaagaaagtt tccaagactt tgagaaaggt ttaacagttt cagaaattga aatggtaaaa
      541 gctttcggaa aatacggctg gagtgaatag atgaaagagt acacgctagt ttattctaaa
      601 agttttcaga ccagccttga aacgataata gaagaatggg aaaatgagct tgctctttct
      661 ccagccagca taaaaagatt tgtaggtgcg atccagaagg ctttagaact aaccaaaaat
      721 tttccaacta tgcatgagga agtttccgaa atctatggaa tggatatccc aacatatcgg
      781 atcgtgatcg gcaaaagcta tgccttattt tatcggatcg accatgaaaa aaaagagata
      841 cttgtaggac gtattttcca atctaaacaa atgaaactag gcttttaaca ataattagga
      901 aaaagtcgct catcctctac aggtgggtga ttaatgccgc tcgatatggt tgttaaccgt
      961 cggttactcg aagattgata tataagactt agtacctttt tattttgctc catgttatgg
     1021 ccgaaggtct aaagatacaa tcattagtct agagaaaaat taagaaccgt aggaactacg
     1081 gggatcgctt ggtgaataag agacactgct attagtgaaa aaataagata tcaagtacgc
     1141 tctattccca aaaatttcgt gactttactc atgagaggtt caagtagtat atttttaatc
     1201 aaaattgacg taacttttaa taaatactac ctaaataagg tagtatttat ttttgtgttt
     1261 taaaagagga agtccaatat atctatggga aacttcttaa atattatgtt ggtacatgaa
     1321 aatatacatc cctgctagac tatttacaac attttacttt gtacgtattc ttgttttaaa
     1381 aggaatggga taaaatatag gtacaataac tatttgatgc taaatataat taatggagga
     1441 gagatagtga acatacttaa tgaaaaaaga tatgtatggt ttgctggtaa aaaatatatt
     1501 actactttca aaagattatc cgagttaatg cagcagactg ttaaaagtgc tatgcctgaa
     1561 ggatacaagt ttaattttgt tcaatcttca gtatctactg aaagtatcta tttttcaatt
     1621 ctttctgaga gtaggctttt tcattttaga ataagttctc atgtaaagaa aactgatgtt
     1681 gatatatata cgttccgtac aaataattat aaaaatttaa atgatttgag tagaagtatc
     1741 agtgaatatc tcaaggggaa tagctatctc aagattcgat tttcacatat attaatttta
     1801 ctaccatatt tgaatgagaa tttcacccta attcaagtag ataagtcttt cattgcctca
     1861 ggtaatcaag gaaatatgaa tattacaagt aacaaaacgt cacgtgtgct attggcgttg
     1921 atgggttacg gaattcttta tagagatgac caaaatggcc agattctaat aaatcgggct
     1981 gggcgttcat tattaatgaa atatagaaaa tttataccgg aagattttca aaacttacag
     2041 ttagaaaaca tgcgtttaga agatttattt agattagcag aagatgataa gtatagattt
     2101 gaagttttga aaattcaaaa gaatgaacta ttgaataagt tatatcctga gaatgcgata
     2161 aaagcacatt ttggtgatgc taatcatatg tatagttggt tcattcctaa aagatttaga
     2221 gggaaaatca atgctggaga tcaagtgaaa gtactcaatc gaaatagtac agatgtcgta
     2281 atgataacag atatctatgt agaagatgaa gatataatca aatatatgaa gcctgtgata
     2341 aaacttgtta ataaaaataa aggaacccgt ggtgctagtt aattttttcc tagag
//
LOCUS       DACBZK010000176         2296 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.184, whole genome shotgun sequence.
ACCESSION   DACBZK010000176 DACBZK010000000
VERSION     DACBZK010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2296
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.184"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..300
                     /locus_tag="IVD66_002879"
     CDS             <1..300
                     /locus_tag="IVD66_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall surface anchor protein"
                     /protein_id="HAP6147036.1"
                     /translation="AAILKSDKEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKV
                     DKDSYKEENRITIKNNQKASVPMTGSNGFQSYVLISCLLLGAGAISAVVYFKKKA"
     gene            313..1065
                     /locus_tag="IVD66_002880"
     CDS             313..1065
                     /locus_tag="IVD66_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP6147037.1"
                     /translation="MIIRHPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVSKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            1081..1836
                     /locus_tag="IVD66_002881"
     CDS             1081..1836
                     /locus_tag="IVD66_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147038.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADSQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGHEKQEGVNG
                     AKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLSSDQLKLVSNGETKTIDQQTGV
                     FEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSEKNGEFLKDVWIYPKSEAS
                     QPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            1849..2109
                     /locus_tag="IVD66_002882"
     CDS             1849..2109
                     /locus_tag="IVD66_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147039.1"
                     /translation="MKLIKLLLFNLSCLTAVFLYCGLLFSQLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            2106..>2296
                     /locus_tag="IVD66_002883"
     CDS             2106..>2296
                     /locus_tag="IVD66_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP6147040.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKT"
BASE COUNT          818 a          385 c          443 g          650 t
ORIGIN      
        1 gcagcaatcc taaaatcaga taaagagggt cattttgaaa tcactggttt aactgaagga
       61 gattactcac tggaagaaac aaaagctcct gaaaactatc aaaaattaac aaaagagatc
      121 tctttcaaag tagacaaaga ttcatacaaa gaagaaaacc gaatcacgat caaaaataat
      181 caaaaagctt ccgtaccaat gactggtagc aacggtttcc aatcttacgt attgatctct
      241 tgcttgttgc ttggggcagg cgcaatttct gcagttgttt actttaagaa gaaagcctag
      301 aaggatcagc taatgattat cagacaccct aagaaaaagc gaatcatggg taaatggatc
      361 attgctttct ggttactttc agctgttggt gtcttacttt tgatgcctgc tgaagcgagc
      421 gtggcgaaat accaacaaaa tcagcagatt gccgcaatcg atcgaacagg aacggcagca
      481 gaaacggatt cttctttgga tgtttctaag attgagttag gcgatcctgt tggtattctt
      541 acaattccaa gtatttcttt aaaactacca atttatgacg gaacttccga caaaatttta
      601 gagaatggtg tagggattac ggaaggaact ggcgatatta caggaggaaa cggtaaaaat
      661 cctttaatcg cagggcacag tggactttat aaagataatc ttttcgatga tttgccttca
      721 gttaaaaagg gagaaaagtt ttatatcaaa gttgatggtg agcagcacgc ttatcaaatc
      781 gatcggattg aggaagtgca aaaagacgaa ctacaaagaa actttgtcac ttacttagaa
      841 ccaaatccca atgaagatcg agtaacgcta atgacatgta cgcctaaggg gatcaacaca
      901 caccgtttcc tagtgtatgg gaagcgagta acctttacaa aatcagaatt aaaagatgaa
      961 gaaaataaga aacaaaaatt atcttggaaa tggcttttag gaagtactgt ttttctttca
     1021 gtcatgatca ttggttcgct atttgtttat aaaaagaaaa aataaaggag ggtaaccaac
     1081 atgagaaata gaaaatggct atttgtttgt gcagccgctc ttttttcttt cactgcctac
     1141 acacagttga cgtttgcaga cagtcaagaa agcacggata gcacagaaca aacaatccaa
     1201 acgtcagata gcagcacgat tcaaagcagc gatgaaaccg tcgattcgtc aacagtggat
     1261 tcttcagaag aaccgaaaat tgctgaagac gatcaaatag tcaaacagac cattcacgtt
     1321 caaaagatta tttcttcaga acaattagac aaccaggggc atgaaaaaca agaaggagta
     1381 aatggcgcga agttttctgt ttatgatgta tcggacattt tacaaaagat ggatgttaag
     1441 gatctcacta ctgaccaaat tgaatcccaa ttaaaagatc gagtgaaaaa actatccagt
     1501 gatcaattga agctagtttc taatggagaa acaaagacaa ttgatcaaca aacaggtgtc
     1561 tttgaattct cggtagaagt acaggcaaat cagaaacaag cttattatat tgtcaatgaa
     1621 tcaagtcctg aaaacatttc taatagcgag gatattttgc tattaacacc tgtttctgaa
     1681 aaaaacggtg aattcttaaa ggatgtgtgg atttatccta aatcagaagc ttcgcaacct
     1741 aaagaagaag taaaaaaaat cgtttctact ggtgtaaaga aaaacttctt tgagaattgt
     1801 tgggattttg ttactcactt gttttctaga gattaaggaa gaaataagat gaaactgatc
     1861 aaattattat tattcaatct ttcttgttta accgcagtct ttttgtactg cggtttatta
     1921 ttttctcaat tatctatttt gccaagctac caactatacc taatgaggat tttaaacata
     1981 ccagctgctt ccatgccgct agatattatg gaaaagctca ttaggaatcc attatttact
     2041 acgatcaatt tgatcgttat tgtcggaatt tcactagtca tttataaaaa agaggggatg
     2101 aagggatgaa ttttaaacac tcgtggacca gacggttaaa atatgttttt cccataatga
     2161 tgatgttagg tacattgttt gggttaaaaa cagccaatgt ctttgctgaa aaagttattg
     2221 tcgatccgtc aaatccaatc cagaacgtaa agaataattt tattattcca aaagatgttc
     2281 ctaatgcaaa aacaaa
//
LOCUS       DACBZK010000177         2261 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.185, whole genome shotgun sequence.
ACCESSION   DACBZK010000177 DACBZK010000000
VERSION     DACBZK010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.185"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            278..820
                     /locus_tag="IVD66_002884"
     CDS             278..820
                     /locus_tag="IVD66_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147041.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            976..1425
                     /locus_tag="IVD66_002885"
     CDS             976..1425
                     /locus_tag="IVD66_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HAP6147042.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPDGMATLFLTKIIRCCECCGVMATIALDNEHPRI"
     gene            complement(1455..>2261)
                     /locus_tag="IVD66_002886"
     CDS             complement(1455..>2261)
                     /locus_tag="IVD66_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HAP6147043.1"
                     /translation="TYYYQAKPIENESDLEEIVQEEFIRNRKAYGTRKLKKCLAKRGL
                     QLSRRRIGRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTFTQEQPLEAIVTDL
                     TYVRVGKKWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYSLTDVKLFHTDR
                     GKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQFETLAQLR
                     LELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          784 a          372 c          429 g          676 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcaaat tgatgaagca gatcccaaag ggctgcttca tcaatttttt
      121 cgtaagtgtc cgtacactta ctgtgcttgc tcatatatta atcgatcata tactaatcgt
      181 gtaagaacaa ctttaagcat aatacttata ttgttatacc atagtttgga aaaataaaaa
      241 attatatttc atcaacgttt cataaaaggt gtgtagaatg ttattgaaag tagctataaa
      301 atgctattgt gtaaaaaata aaggaggaat aatttatgaa aaaatagtac caagaggagc
      361 atgcctatta cttgcattat gtttgagctt aagcgcagtt gggtgtcaaa aaagtaatga
      421 aaacaataaa ataaaagaag gacaatccat aagttctgaa gaggaaggca tgtcaattaa
      481 tgcaaatggc aaaaatgaaa cttttaagcc atcagattat acattggagg caaagaaaga
      541 atatgtttat gaatatttag ggcttaaatt taaactctca gacaaattta gaaattatat
      601 agctgataaa aagatagcga tgttagatga tcaaagtcct atagataaag aactaaagta
      661 tgctattttg acatttgaga aaatgacaga agaacaaaag aatgcagtta tagaaaagat
      721 gggcgatgga tataaaaatt ggcaaaatga gcttgaaaga attgggacta ttggtatatt
      781 tgaaaaaaat acatcagaag aaaaaaatct aaaattataa aatgtgatac tcatactaaa
      841 ataggagttt caagtgatgg aaaatacgat tgctatttaa gcacaaatag cggagctgaa
      901 agtaatcttc tggatgaatt aaaaagaact gagattcaaa ttatagataa aaaagaacgt
      961 cctaaaaatg gttttgtgct atcagaaaaa actgatttag aaaatacaga agcatttaac
     1021 aaagaatcgg ttaaagattt acgtaaacta ccaacaaagg acataaatgg caaggatttt
     1081 acaagtaaag attttgagaa gtatgatctt actatggtaa atgtatttgc aacttggtgt
     1141 acagcttgtg taaaggaaat tcctgatttg gttgaggttc agaatgaaat gaaaagcaag
     1201 ggtgtaaata tcgttggagt tgttacagat cctgttgatg ataacggtga aaacaaggaa
     1261 gcaattgaaa agtcaaagtt aatacatgaa aagacaaagg cttcatatcc tttcttaatg
     1321 ccagatggaa tggcaacact ttttttgaca aaaattataa ggtgttgtga atgctgcggt
     1381 gttatggcta cgattgccct tgacaatgag catcctcgga tctgattttc tccggcagaa
     1441 gcacaatcat tcaattacgc tgcctctcca gaggtatcag atccgcgctc attatcaagg
     1501 attcgcttcg ccaatctctg ttgtcgaatt tggatcggtg tttcatacgc caacgtgcca
     1561 tgtaagcgta gatagttcca ccaatgcaca taatcaaaca attctagacg tagctgtgcc
     1621 agtgtctcaa attggtattg atgcacgaat tctactttga cagatttata ggttgattcc
     1681 acaacggcat tatcatacgg acaacccttc ctactcaatg aacgagtaat tccaaaacca
     1741 ttcagaatct catgaatggt ttggttatca aattcctttc cccggtctgt atgaaaaagc
     1801 ttgacgtctg ttaaagaata cggtatccgt ccaaaggctt cttttaccaa tgaggcatct
     1861 ttcttctcac cacaggaata accaataatt tctcgattaa acaaatcaag tattaagcag
     1921 atataatgcc actttttccc cacgcgaaca taagtaagat ccgtaacgat ggcttccaat
     1981 ggctgttctt gtgtaaaggt ccgatctaat acattcgctg ttttcgcttc attacaagct
     2041 gttcgttgcc ctttaaaatg agcgatcgta taggtagatg tcaatccgcg gcgtttcatg
     2101 attcgaccga ttcggcgccg actgagttga agcccacgct ttgctaaaca cttcttcaat
     2161 tttcgggtac cgtaagcctt tcggtttcga ataaactctt cctgaacgat ctcttctaag
     2221 tcggactcat tttcgatcgg tttcgcttga taatagtagg t
//
LOCUS       DACBZK010000178         2182 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.187, whole genome shotgun sequence.
ACCESSION   DACBZK010000178 DACBZK010000000
VERSION     DACBZK010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2182
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.187"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            74..1489
                     /locus_tag="IVD66_002887"
     CDS             74..1489
                     /locus_tag="IVD66_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HAP6147044.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKTNDWHKHIDFTKSDEN
                     IYLEQTNLADKYEELFGEVVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     ILDDFQTNRADGSSTGISKQQAEQNRVIANKILVQYYKEFQERNPNLAVYNAVIHNDE
                     ISPHLHLNIVPVAEGYKRGVQKQPSFNKALVQQGIHADKDNGRVLFNNFRNQEVDSIE
                     RLMNDYGWKRDIVGTNKIKDIHEYKEIMSEISELRQTAVKERESISAEMRYISKQREK
                     NEREKALVASEKAKIEEEKKSIIDLEKELAVVFQKDPVPLNSFEKLSDGSYRLSSADF
                     VDLYQKASNATNSKKYADMANESLGNTLDKNIALFDKNMALEQENSFLKNQQKVDVSA
                     VVAENKKLKEENRSLRRRLTQLKNAFQKSITRLSIRFGLVEKDMGISEELKILDQEKT
                     LASQQNAPERNIGRSENEMEW"
     gene            1938..>2182
                     /locus_tag="IVD66_002888"
     CDS             1938..>2182
                     /locus_tag="IVD66_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAP6147045.1"
                     /translation="MSKKGTIINEWEKLTAPSNRRLSVPFMDTPLKIQWSIDRITIVG
                     NLKENIYYHTTHDVLILDFEQLMRLNEGNGYLRSVSN"
BASE COUNT          771 a          331 c          471 g          609 t
ORIGIN      
        1 ttactctttg acaaagagta acagaaaggt ttacactctt tttattagcg acagcgcgaa
       61 ggagggtttt aacttggggt ttagtatttc atttaaaaaa ggaacgaaga atacaagtat
      121 ttctcataat aatcgtgagt taactgatag ccagaaaacc aatgattggc ataagcatat
      181 tgacttcacg aaatcggatg aaaatattta tttagagcag acgaatctag cagataaata
      241 tgaggaattg tttggcgaag tggtagaaaa atataatgcg aaacaaaaaa gagccgatag
      301 aaaaatcgag gactatttag cgaaagtgcg caaggataaa aagttggaac ctcaacgaga
      361 atttattgtg caaataggca ttttagatga tttccagaca aatcgagcag atggttcttc
      421 tactggcata tcgaaacaac aagctgaaca aaatcgagtg attgccaata aaattttggt
      481 tcagtattac aaggagtttc aagagagaaa ccctaatttg gctgtttata atgctgttat
      541 tcataatgac gaaataagtc cgcacctgca cttgaatatt gtgccggttg ctgaaggtta
      601 taaacggggt gttcaaaagc agccgagctt taataaagca ctggttcaac aagggataca
      661 cgctgataaa gataatggtc gagtgctttt caataatttt agaaatcaag aagttgactc
      721 tatagaacga ttaatgaatg attacggttg gaaaagggat attgtcggta ccaacaaaat
      781 taaagatatt cacgaataca aagaaatcat gagtgaaatt tctgaattgc gccaaacggc
      841 tgtaaaagag cgtgagagca tttctgcgga aatgaggtat atttctaagc aaagagaaaa
      901 aaacgagcgt gagaaggctc tggtggcttc tgagaaggcg aaaattgaag aagagaaaaa
      961 atcgattatc gatttggaaa aagagctggc tgttgtattt caaaaagatc ctgtgccact
     1021 caatagtttt gaaaaattat cagatggttc ttatcgctta tctagtgctg attttgtaga
     1081 tttgtatcaa aaagcgtcta atgctacgaa cagcaaaaaa tatgctgata tggcgaatga
     1141 atcgcttgga aatacattag ataaaaatat cgctttattt gataaaaaca tggcgttaga
     1201 acaagaaaat tcttttttga aaaatcaaca aaaggttgat gtgtcagcgg ttgttgctga
     1261 aaacaaaaag ctgaaggaag aaaatcgttc tttgcgtcgg cggttaactc aactgaaaaa
     1321 cgcatttcaa aaatcaatca ctcgtttatc aattcgtttt gggcttgtag aaaaagatat
     1381 gggaatatct gaagagctaa aaatattaga tcaagagaaa acgttggcta gtcagcagaa
     1441 tgccccagaa cgtaatatag ggcgttctga gaatgagatg gagtggtagt tatacggtgc
     1501 agtcaacggt accggaggcg gtctgtgccg aggataagga gttgacggct aaaccactaa
     1561 tccctgaagc tgacatttgc taaaaaatgg caagtccatt ttttggccaa cttagcgtta
     1621 gcgaagtttg ggggcgccct tttcaaaggg tgcggtttta tgtttttgga tatttgcata
     1681 gctaaagaga agtgctatta ttgagttatc aaataaataa actgaaaaaa gagcaaaaaa
     1741 ataaagtcga gcaacgctgg acacgttctc gacctttacg gaaactaatc acactagctc
     1801 cgtaactcaa attcattata cgaataattt caggtttctt caagactaga gattgctggt
     1861 tatgaatttt ttagagttac gtgaactctg gaaaattctt tccaccaatc tcttttttct
     1921 ttgaggagga actaaatttg agtaaaaaag gcacgatcat aaatgagtgg gaaaaattaa
     1981 cagccccctc taacaggcgg ttaagtgtcc cttttatgga caccccccta aaaattcagt
     2041 ggtcaatcga ccgaattacc attgttggaa atcttaaaga gaatatctat tatcacacta
     2101 cacatgatgt gttgatttta gattttgaac agcttatgcg cctaaatgaa ggtaacggtt
     2161 atttaagatc tgttagtaat aa
//
LOCUS       DACBZK010000179         2164 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.188, whole genome shotgun sequence.
ACCESSION   DACBZK010000179 DACBZK010000000
VERSION     DACBZK010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2164
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.188"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..111
                     /locus_tag="IVD66_002889"
     CDS             <1..111
                     /locus_tag="IVD66_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016204422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6147046.1"
                     /translation="YAVKLYKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            325..1020
                     /gene="vanR"
                     /locus_tag="IVD66_002890"
     CDS             325..1020
                     /gene="vanR"
                     /locus_tag="IVD66_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAP6147047.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            998..2152
                     /locus_tag="IVD66_002891"
     CDS             998..2152
                     /locus_tag="IVD66_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAP6147048.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          730 a          400 c          461 g          573 t
ORIGIN      
        1 tatgcggtaa agctatataa agaaggaaat atgactgtaa atcaaatttg tgaaattact
       61 aatgtatcta gggcttcatt atacaggaaa ttatcagaag tgaataatta gccattctgt
      121 attccgctaa tgggcaatat ttttaaagaa gaaaaggaaa ctataaaata ttaacagcct
      181 cctagcgatg ccgaaaagcc ctttgataaa aaaagaatca tcatcttaag aaattcttag
      241 tcatttatta tgtaaatgct tataaattcg gccctataat ctgataaatt attaagggca
      301 aacttatgtg aaagggtgat aactatgagc gataaaatac ttattgtgga tgatgaacat
      361 gaaattgccg atttggttga attatactta aaaaacgaga attatacggt tttcaaatac
      421 tataccgcca aagaagcatt ggaatgtata gacaagtctg agattgacct tgccatattg
      481 gacatcatgc ttcccggcac aagcggcctt actatctgtc aaaaaataag ggacaagcac
      541 acctatccga ttatcatgct gaccgggaaa gatacagagg tagataaaat tacagggtta
      601 acaatcggcg cggatgatta tataacgaag ccctttcgcc cactggagtt aattgctcgg
      661 gtaaaggccc agttgcgccg atacaaaaaa ttcagtggag taaaggagca gaacgaaaat
      721 gttatcgtcc actccggcct tgtcattaat gttaacaccc atgagtgtta tctgaacgag
      781 aagcagttat cccttactcc caccgagttt tcaatactgc gaatcctctg tgaaaacaag
      841 gggaatgtgg ttagctccga gctgctattt catgagatat ggggcgacga atatttcagc
      901 aagagcaaca acaccatcac cgtgcatatc cggcatttgc gcgaaaaaat gaacgacacc
      961 attgataatc cgaaatatat aaaaacggta tggggggttg gttataaaat tgaaaaataa
     1021 aaaaaacgac tattccaaac tagaacgaaa actttacatg tatatcgttg caattgttgt
     1081 ggtagcaatt gtattcgtgt tgtatattcg ttcaatgatc cgagggaaac ttggggattg
     1141 gatcttaagt attttggaaa acaaatatga cttaaatcac ctggacgcga tgaaattata
     1201 tcaatattcc atacggaaca atatagatat ctttatttat gtggcgattg tcattagtat
     1261 tcttattcta tgtcgcgtca tgctttcaaa attcgcaaaa tactttgacg agataaatac
     1321 cggcattgat gtacttattc agaacgaaga taaacaaatt gagctttctg cggaaatgga
     1381 tgttatggaa caaaagctca acacattaaa acggactctg gaaaagcgag agcaggatgc
     1441 aaagctggcc gaacaaagaa aaaatgacgt tgttatgtac ttggcgcacg atattaaaac
     1501 gccccttaca tccattatcg gttatttgag cctgcttgac gaggctccag acatgccggt
     1561 agatcaaaag gcaaagtatg tgcatatcac gttggacaaa gcgtatcgac tcgaacagct
     1621 aatcgacgag ttttttgaga ttacacggta taacctacaa acgataacgc taacaaaaac
     1681 gcacatagac ctatactata tgctggtgca gatgaccgat gaattttatc ctcagctttc
     1741 cgcacatgga aaacaggcgg ttattcacgc ccccgaggat ctgaccgtgt ccggcgaccc
     1801 tgataaactc gcgagagtct ttaacaacat tttgaaaaac gccgctgcat acagtgagga
     1861 taacagcatc attgacatta ccgcgggcct ctccggggat gtggtgtcaa tcgaattcaa
     1921 gaacactgga agcatcccaa aagataagct agctgccata tttgaaaagt tctataggct
     1981 ggacaatgct cgttcttccg atacgggtgg cgcgggactt ggattggcga ttgcaaaaga
     2041 aattattgtt cagcatggag ggcagattta cgcggaaagc aatgataact atacgacgtt
     2101 tagggtagag cttccagcga tgccagactt ggttgataaa aggaggtcct aagagatgta
     2161 tata
//
LOCUS       DACBZK010000180         2082 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.189, whole genome shotgun sequence.
ACCESSION   DACBZK010000180 DACBZK010000000
VERSION     DACBZK010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2082
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.189"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..375
                     /locus_tag="IVD66_002892"
     CDS             <1..375
                     /locus_tag="IVD66_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAP6147049.1"
                     /translation="IFKGANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFS
                     DIQKLSLGEVMDLVSNDGVYRYKVTRKFIVPGYFKLIDGVPEENSFLSLPKKGEKPLL
                     TLFTCVYTSQGKERYVVQGELQ"
     gene            428..>2082
                     /locus_tag="IVD66_002893"
     CDS             428..>2082
                     /locus_tag="IVD66_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP6147050.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYQVHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAV"
BASE COUNT          750 a          319 c          466 g          547 t
ORIGIN      
        1 atttttaaag gggcaaatca atacactttg agtcttggag cggctactta tttttatgaa
       61 gatgccgaaa tgggcaaagg aaactatgtc ctagcaggtc ataacatgga aatgccaggt
      121 gttttatttt ctgatattca aaagttgtca ttaggggagg tgatggactt agttagtaac
      181 gatggcgtct atcgttacaa ggtaacgcgt aaatttatcg tacctgggta ctttaaatta
      241 atcgatggcg ttcctgaaga gaactctttc ttgtctttgc caaagaaagg agagaaaccc
      301 ttattaacgt tgtttacttg tgtttatacg tcacaaggaa aagaaagata cgtggtacag
      361 ggagagctac aataacaagg ttttaatcaa cgcgagtcgt tgaaatatga aatgaggaga
      421 gtaaaaaatg gcaataaatc ggtatgtaaa aaaagctgga atgcttgttg gaatgttagg
      481 aatcattgca ggctgctttc aggggtatca agtacatgca gaagatgtca cgcaaaaaac
      541 accaccagag aaggtcaata tcacggttca taaattaatg tacgatcaag gaacgcaatt
      601 gaatgttgat attgacggga tcaaaaacga tggttatacg cacgatcaat atcctacagg
      661 tgtaacgaaa tacaacaagg cagattatgg tgatgttgag tttacgttag gaaatattac
      721 ggatcaagta ttaccgagag aagattctga tctaaccaac gcgaaagtgg acgagattgt
      781 acaagatgta gaagacaagg gatctaacag tgagtacgtc aagaatgcaa ccaacaaaat
      841 tacttcagct gtagatgaaa atggtgagat cacttttact gatcaaccag cctatgtcaa
      901 ttccaaaggg aatgtatatg tggtttatga aagtaaatcc gctgctggat tagtcacaca
      961 aaaagcaaaa ccaatggttg tgattgcgcc aatgacagat aaaacaggat caggattttt
     1021 aaaaaatatt catttgtatc ctaagaacat tgtttctaag ttgagttttg aattaacgaa
     1081 atttggtgac gatggcgcag accaaagcaa acaaaccctt ttaaaagggg caaaatttga
     1141 gttatacaag ggcgaacctg gaaaaggaac aaaattgggt gatcttgtat cggatgatca
     1201 aggaaagctg actgcgactg atttgacgtt aggaaaatac tattttgtgg aagttccttc
     1261 ggaagttgta gtgggatcag atcaagaacc aacagcagat caatatttat taggcgcaga
     1321 cgctcgcaac gatgcgcaca ataaattaac ctttgaaatt acgaatgatg gcgtgacaag
     1381 tgacttaaaa gcttcatacg taaactataa agcaccagtg atcgataaaa cagtaacaaa
     1441 tggaacagga caagaacatt ctttccaaat tggtgacgca gtaaattatc aaggaacgat
     1501 tcatattcca acagacattg caggtggcgc agacggtatc acagtaaacg gtgtgaaaag
     1561 cgaaacttct ccttacagtg tatttaaatg gggagataca gcaggtaaag gactttctta
     1621 tgttgctgaa aaagcagata ttaaagtaac aaataatgat ggttcagtcg tattaaaaga
     1681 aaatactgac tataaaatcg aaaattctga tagtggtttt gtgatcgatt ttatcgtaaa
     1741 taatggacaa gtaagtgata cagttgcgaa tttacatggt caagatctaa aaatgactta
     1801 taacatgttt gtgaatgata gtgctgaaat cgcaaatcca ttaacaaata gcgtggattt
     1861 cgtttataac aataatccat ttaatcagga agaacaccac gaaaaaacga aagctgacgt
     1921 tgtgacttat ggcgcaaaat tcttaaaagt cgatagcggc ctatttggaa caggtatcaa
     1981 agcaacaccg cttgaaggcg cagaatttgc agctaagaat gcagaaggta agtactacgg
     2041 tggacttact gatacagata aagatggtgt caaagaagca gt
//
LOCUS       DACBZK010000181         2081 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.190, whole genome shotgun sequence.
ACCESSION   DACBZK010000181 DACBZK010000000
VERSION     DACBZK010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2081
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.190"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..375
                     /locus_tag="IVD66_002894"
     CDS             <1..375
                     /locus_tag="IVD66_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAP6147051.1"
                     /translation="IFKGANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFS
                     DIQKLSLGEVMDLVSNDGVYRYKVTRKFIVPGYFRLIDGVPEENSFLSLPKKGEKPLL
                     TLFTCVYTSQGKERYVVQGELQ"
     gene            427..>2081
                     /locus_tag="IVD66_002895"
     CDS             427..>2081
                     /locus_tag="IVD66_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP6147052.1"
                     /translation="MAINRYVKKAGMLVGMLGIIASCFQGYQAHAEDVTQKTPPEKVN
                     ITVHKLMYDQSTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVIYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTEQSKQTPLKGAKFELYKGEPGKGSKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDKEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQVGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAV"
BASE COUNT          744 a          337 c          464 g          536 t
ORIGIN      
        1 atttttaaag gggcaaatca atacactttg agtcttggag cggctactta tttttatgaa
       61 gatgctgaaa tgggcaaagg aaactatgtc ctagcaggtc ataacatgga aatgccaggt
      121 gttttatttt ctgatattca aaagttgtca ttaggggagg tgatggactt agttagtaac
      181 gatggcgtct atcgttacaa ggtaacgcgt aaatttatcg tacctgggta ctttagatta
      241 atcgatggcg ttcctgaaga gaactctttc ttgtctttgc caaagaaagg agagaaaccc
      301 ttattaacgt tgtttacttg tgtctatacg tcacaaggaa aagaaagata cgtggtacag
      361 ggagagctac aataacaagg ttttaatcaa cgcgagtcgt tgaaatatga aatgaggaga
      421 gtaaaaatgg caataaatcg atatgtaaaa aaagctggaa tgcttgttgg aatgttagga
      481 atcattgcaa gctgctttca ggggtatcaa gcacatgcag aagatgtcac gcaaaaaacg
      541 ccaccagaga aggtcaatat cacggttcat aaattaatgt acgatcaaag tacgcaattg
      601 aatgttgata ttgacgggat caaaaatgat ggttatacgc acgatcagta tcctacaggt
      661 gtaacgaaat acaacaaggc agattatggt gatgttgagt ttacgttagg aaatattacg
      721 gatcaagtat taccgactga agattctgat ctaaccaacg cgaaagtgga cgaaatcgtg
      781 aaagacgtag aagacaaggg atctaacagt gagtacgtca agaatgcaac caataaaatt
      841 acttcagctg tagatgaaaa tggtgagatt acttttgcgg atcaaccagc gtacgtgaac
      901 tcaaaaggaa atgtgtatgt tatttacgag agtaagtccg cagcaggatt agtaactcaa
      961 aaagcaaaac caatggtggt cattgctcca atgactgaca acacaggttc aggtttttta
     1021 aaagacattc acttatatcc taaaaatatt gtttctaagt tgagttttga attaaccaaa
     1081 ttcggtgatg atggtacaga gcaaagcaaa caaacccctc ttaaaggcgc taaattcgaa
     1141 ttgtataaag gagaacctgg aaaaggaagc aaactaggcg atcttgtttc ggatgatcaa
     1201 ggaaagctga ctgctactga tttgacgtta ggaaaatact attttgtgga agttccttca
     1261 gaagtcgtag tgggatcaga taaagaacca acagccgatc aatatttatt aggcgcagac
     1321 gctcgcaacg atgcgcacaa taaattaacc tttgaaatta cgaatgatgg cgtgacaagt
     1381 gacttaaaag cttcatacgt aaactataaa gcaccagtga tcgataaaac agtaacaaat
     1441 ggaacaggac aagaacattc tttccaagtt ggtgatgccg ttaattatca aggaacgatt
     1501 catatcccaa cagacattgc aggcggagca gacggtatca cagtaaacgg cgtgaaaagc
     1561 gaaacttctc cttacagtgt atttaaatgg ggggatacag caggacaagg actttcttat
     1621 gtcgctgcta aagcaaatat caaagtaaca aataaagatg gatcagtggt attaaaagaa
     1681 aatacagatt ataagatcca aaattcagaa aatggctttg tgatcgattt tatcgtaaat
     1741 aatggccaag taagtgatac tgtagcaagt ttacacggac aagatcttca aatgacttat
     1801 aacatgtatg taaatgacag cgcagctgtt gccaatccat taacaaatag cgtggatttc
     1861 gtttataaca acaatccatt taatcaggaa gaacaccacg aaaaaacgaa agctgacgtt
     1921 gtgacttatg gcgcgaaatt cttaaaagtc gatagcggac tatttggaac aggaattaag
     1981 gcaactcctc ttgaaggcgc agaatttgca gctaagaatg cagaaggtaa gtactacggt
     2041 ggacttactg atacagataa agatggtgtc aaagaagcag t
//
LOCUS       DACBZK010000182         2027 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.191, whole genome shotgun sequence.
ACCESSION   DACBZK010000182 DACBZK010000000
VERSION     DACBZK010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.191"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            484..663
                     /locus_tag="IVD66_002896"
     CDS             484..663
                     /locus_tag="IVD66_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147053.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            722..1078
                     /locus_tag="IVD66_002897"
     CDS             722..1078
                     /locus_tag="IVD66_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147054.1"
                     /translation="MLKTKKNSYKLKLSILSIICLLGMIISGHLYRVAYTQFIEYKVH
                     SLGLAGDRYVEYVHYSLKCSSYILLWLIFSLFELLNLIAISSYHLDKLNTKSSRYNEV
                     FKENVKLESDLNKLKK"
BASE COUNT          718 a          275 c          386 g          648 t
ORIGIN      
        1 tattacacca tgaaaaagga agacaacgaa aatgaataag gtgatttatc aactaacaac
       61 ggattccata tcaacgattt gaaagaaaaa aaggtcaata atcatttata ccgaaaagtg
      121 agaatgtgtg aaacaaggac aaaaaaagcc tagtaactaa ggaaatggtt cttatttcgc
      181 accaatcgct ccaaccgccc ccgccgctta ggtggtgcga aataaacggg caaagcccga
      241 taacttaaga gaaagaaggt gatccatttg aacaagatta ttcccttatt gttagtactg
      301 tttgttggcg aaatacttat gcgagatagt gcagctgtac agttaaacct cgctgtattt
      361 ttggtaatac tggtgttttg tttgatcttt tggcggtttg tattagtcct cgtgagtcta
      421 ctattcaaga tgattgcagc catatttttc atagggttat ttcgatgaaa ggagtgagta
      481 ccaatgccaa ttgcaatagg aaataaacgg ttacccgtga cattagatga aaagagacaa
      541 aaagaattgc agcaactaaa gcagaagtat ggcaaaagtg aatctaagat tatgtgtatt
      601 gcgttagatc tattgatcgc gcaagaaaaa gcaggatttg atgtaccagc gctaaaaaag
      661 tgacgtcact ttttaatttg atctatataa gtgatatcac ttttaccaag gagggaatta
      721 aatgttaaaa actaaaaaga attcgtacaa attaaagctt agtatactat ctattatttg
      781 tcttttaggc atgataatta gtggtcattt gtatagagtg gcatatacgc agtttattga
      841 gtacaaggtt cactctttag gattagctgg ggatcgatac gttgaatatg tccattattc
      901 attaaaatgt tcttcatata ttcttctttg gcttattttt tcattgtttg aattgctaaa
      961 tttaatagca atatcttcat atcacttaga taagctaaat accaaatcta gccgttataa
     1021 cgaagtgttt aaggaaaatg tgaagttaga aagtgactta aacaagctaa aaaaataaaa
     1081 agaagaaaac ataagttaac taaaattatt ttattaagaa tgatggaata taaggataag
     1141 gttaccaaca taacgatcat tacttctctg atatgctatg gacttctatc aatcagtatt
     1201 ttgtctatag attatggagt aactatactg caagccttag ttttggctat gcctatgtat
     1261 ctatctttgt ttatcatgca tgaaatatat aagctatttg ttttatcaaa aaatgtagaa
     1321 atacgggtaa atattttggt gaatagttat caaaaagaac tcaaagaaag aagacggtgg
     1381 cggtatttat tgaaaggatg aaaaagtagg atttgacata ctggtattca gaaagtgccg
     1441 tcacttttaa aacaatggaa aaggtggaga taagatgaag aaaaaacaaa ctaaactatc
     1501 attagcagat atttaacaca gttaaccgca actgaagatg gtgttgttga atttgaacaa
     1561 tctgaaattg cggtagtaga tgatcgttac cttaaaatgc cttacttctt tgaccaagca
     1621 aaggtcattt gcctttgtca ctacgatggg gtacgtgatt ttaggcgtta aaaagtagtg
     1681 attatatcaa ctttacgagt aaatataaat ttagacatga aactgaatta tccaatggaa
     1741 aatcatggtt tataatctag aaaaattata gtaatgattg gattatatat attctttcgt
     1801 attttcgtac aactgtagct tgtcaaaatt gagaaattta accgattagg tactttacat
     1861 cgttatttgg gtaatttcta aaacatgaag cttaccaacg aataaactga gactatctta
     1921 ttaattgatc aatataagaa aatatctttg aggagatgat gtactatgtt ttcgtctatc
     1981 cacgattggt taggtggtct tttcggcggt ggaggtaaag gttttta
//
LOCUS       DACBZK010000183         2019 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.192, whole genome shotgun sequence.
ACCESSION   DACBZK010000183 DACBZK010000000
VERSION     DACBZK010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2019
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.192"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            101..571
                     /locus_tag="IVD66_002898"
     CDS             101..571
                     /locus_tag="IVD66_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HAP6147055.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            793..1896
                     /locus_tag="IVD66_002899"
     CDS             793..1896
                     /locus_tag="IVD66_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAP6147056.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
BASE COUNT          687 a          327 c          460 g          545 t
ORIGIN      
        1 agaatctctg aagaataaat cacgtgatcg tgacgataaa atacacttac gtcaggtgat
       61 aaaaaataca taagtagaaa actaagagga ggaacagaaa atgaaagaag ttcaattgat
      121 cagaaaaagc gaactatcag aaggtggttg caatgcatgc ggcgtagtag aagcaacaag
      181 ctatacatta aagcttggtg ccaacaaagc gataatctct gagttgacag taggcggtct
      241 tgtggacagt ctggcgcttg ctgaaggttt tattggagaa gatatttatg agatgttttc
      301 agaaatccgt cagttaaaaa aaggggaaaa ctgcatagag gttcatcatg agagcccgaa
      361 tgtgagattc aaacgtggtg ataatgagat gatcttcaat aatcatgtgt ccgatcacac
      421 cgagctatat ggaatcgtga atcaaatact aactgagctt tttggattgg gaccttatgc
      481 gttcaaggaa gaaaacggta atccaaaatt aaacgaagaa tggcaagaaa cgattgaaat
      541 acaaagaaac aacccgcact tatttcaata ggcatccaca gtatttcgta aaagggactt
      601 tgacacgact tttgtcaaaa tcccatcgtt ttttatctat ttgtgttcta aacatttctt
      661 tcagagtagt aacaactgga atgactgaaa tgtaaacaga ttatttgcct gtatcaatac
      721 ggaagagtaa tataaagtgt gtaaacgcta tcatattatt cattcaattt tttatagagg
      781 gaaggcattg aaatggaaaa aacgtatcaa gcaggtacaa atgaaggaat agtggatttt
      841 atcaatatgg aagatttaga aatagccgct tcacaagtga ttccagctgg tggttatggt
      901 tacatcagca gtggtgctgg cgacttattt acttatcaag aaaatgaacg ggcattcaat
      961 catcagctga ttattcctca tgtattaaga gatgtagaat tacccgatac aactacacat
     1021 tttgacaaag aaacgctgac tgcaccaatc atcatggcac cagttgctgc tcatggctta
     1081 gctcatgtga aggcggagaa agcttctgca aaaggtgtag cagattttgg gacgatctat
     1141 acagcaagtt cttacgcttc ttgtacatta gaagagataa gagaagcagg cggggagaaa
     1201 gcaccgcaat ggtttcaatt ttatatgagc aaagatgatg ggatcaattt ggatattctt
     1261 gaagtggcca agcgtaatgg agcaaaagca atcgtattga cagcggatgc aacagttggc
     1321 ggaaaccgtg aaacagaccg cagaaatggg tttaccttcc cactgccaat gccgatcgtt
     1381 caggcttatc aatcaggagt aggccaaacg atggatgctg tgtacaaatc ttccaaacag
     1441 aagcttagtc caaaagatgt agaatttatt gctgctcatt ctgatttgcc agtctatgtg
     1501 aaaggtgtcc agtcagaaga agatgtctat cgttcattag aatctggtgc tggcggaatc
     1561 tgggtatcta atcatggtgg ccgtcaacta gatggtggtc cagcagcgtt tgattcgttg
     1621 caatatgtgg cagaagcagt agataaacgt gtaccaatcg tgtttgacag cggtgtacga
     1681 cgcggacagc atgttttcaa agcaatcgca tcaggtgcag atcttgttgc tattggcaga
     1741 cccgttattt atggattgtc tttaggagga agtacaggag tccatcaagt gtttgatttc
     1801 tttaaaacag aattggaaat ggtcatgcaa ttagctggaa cacaaacagt agaagatatc
     1861 aaaaaaataa aattgcgtga gaatcgtttt atttaagaaa caaatgacga aaaaaatagg
     1921 agtgcggcag atgatgccgt actcctattt ttatagttca aggatgtcac taatagaata
     1981 atttgaaacg aaaaaataaa attgaaatat tttttcata
//
LOCUS       DACBZK010000184         2000 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.193, whole genome shotgun sequence.
ACCESSION   DACBZK010000184 DACBZK010000000
VERSION     DACBZK010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.193"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..375
                     /locus_tag="IVD66_002900"
     CDS             <1..375
                     /locus_tag="IVD66_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAP6147057.1"
                     /translation="NVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFRR
                     FPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTDD
                     WQKVMAAEVIATYLDGDLVYKK"
     gene            423..1823
                     /gene="yfcC"
                     /locus_tag="IVD66_002901"
     CDS             423..1823
                     /gene="yfcC"
                     /locus_tag="IVD66_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAP6147058.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1856..>2000
                     /locus_tag="IVD66_002902"
     CDS             1856..>2000
                     /locus_tag="IVD66_002902"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP6147059.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAF"
BASE COUNT          552 a          339 c          432 g          677 t
ORIGIN      
        1 aatgtttcca cagaggactt ctttaattat tgtcgattag aggaaagtgg tgtaacagtc
       61 actagcggta cagatttacc gctgtttatt actgatattc ctgaatcgat tataagagca
      121 gtattccgtc gttttcctga aggagaagaa gtctgggaga aagaaacaag cttcacgaca
      181 accgagctgc tgaaaagttt tacaagcaac agcttcaaag taaatggttt atcggagtac
      241 ggagaaataa aagtagggaa aagcgccagc ttagctgttt tcagcgagga cctctgtact
      301 gatgactggc aaaaagtgat ggctgcggaa gttatcgcta cctatcttga tggtgactta
      361 gtttacaaga aataatgctt ttcgatataa cgttataaaa cgaattaaag agaggttaaa
      421 aaatggaaac aatgaaaaga aaattcacct tcccacatag ttatacattg atttttatct
      481 taattatttt ggctgcaatt ttaacttgga taattcctag tggtcagttt gagacagttg
      541 ttgaaaacgt cgcaggtatg gaaaaaacaa cggttgttcc gggaacctat caccaaatcg
      601 ataaggcaga ttatggacaa ggtttttcct ctatactaat ggcaccagct gaagggatta
      661 tttcagctgt tgaggttgtt gcttttgttc tcatcgttgg tggtgccttc gggattatcc
      721 taaaaacggg agccatcgat cgagggctgt ttaccttagc aaaagttctg ggagacaagg
      781 ggatcttagt tattccgatg tcgatgattc tattcagctt aggaggatca acctttggca
      841 tgagcgagga agtcattccc ttatttgcgg tgtttatttc tctgatgttt tctcttggct
      901 atgattccat gactgcgatc ttgattctat ttttaagtac acaagcggga tatgttgggt
      961 cgacgattaa tcccttcaac gttttaatcg cacagggagt agctggcgtt tacggaaatc
     1021 ccctgctttg gtttcggatg ctatcctgga ttgtcattac tgggatttca attgttttca
     1081 ccatgcttta tgctagcaga gtcaaaaaga atccactgtc ctctattgtt tatgagagtg
     1141 atttaaaggt taagcataag tttcaaaatt ttgacactga aaaagagttt tcaacacaag
     1201 ataaactaat tatcgccggt tttatcgtag gtttaggaat catgatttgg ggtatcattt
     1261 ccaagggatg gtatatggtt gaaatttctg cactattctt aggattaggt ctttttgctg
     1321 ggggcatcgc tagattttct caaaaggaaa ttgctgaagc ttttgtcgaa ggctgttcag
     1381 atttcgccta tgctgctgta atcattgggc tagctagagg agtcttggta atcttggaag
     1441 gtggaatgat tattgacact attctaaaca gcttggctaa ccttttaggt ggtcttccaa
     1501 aattcctgtt cactacgatt ctactcattt ctcaagtaat tgtttccttt tttgttccat
     1561 cctcctcagg agctgcggca ttaacgatgc cggttatggc accattgggt gatctaatga
     1621 atgtaagtcg tgatgttgtt gttctaagta accagtttgg aaatggttta atgaatatta
     1681 tctccccaac tagtggtgta ttactggcag gattagccat cgcagagatt aatttctcta
     1741 aatggtttaa ggttggcttc aaaatatttg ccatcttaac ccttgtttct gctgttttgt
     1801 tatacattgc tacactcttt tagtcttaat catccattaa taggaggcaa tagttatgat
     1861 taaaataaat caattagcag gaatgaatat ccactattta ttttattctc tcaaagaatt
     1921 tttcgcttat caacagaaaa ttggtatttc ttctgttgaa ctttggggag gtgctccgca
     1981 ttttttcata gatgctttta
//
LOCUS       DACBZK010000185         1980 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.194, whole genome shotgun sequence.
ACCESSION   DACBZK010000185 DACBZK010000000
VERSION     DACBZK010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.194"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(325..529)
                     /locus_tag="IVD66_002903"
                     /pseudo
     CDS             complement(325..529)
                     /locus_tag="IVD66_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(729..1745)
                     /locus_tag="IVD66_002904"
     CDS             complement(729..1745)
                     /locus_tag="IVD66_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAP6147060.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPISFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERK
                     KVIVPKEIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDKIVIDGL
                     IAEPSNWSIIARHTKYKYRNLLKQESQNDELTNHLRETFKESADELKKELDTWLLGLD
                     VTEK"
BASE COUNT          558 a          459 c          309 g          654 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggttttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cacgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaaaa attttcctaa ttgtgacatg gctgtcacaa
      541 ttccaaatgc tctccgaggg tattcgctgt cacaagtgac aacgaaaaaa ggagccgaaa
      601 gcgtgtcacg ctctcaactc cttttacgct ttattttgct tcatgcaaaa tattcgctta
      661 tcgtgaattt acgtcactaa acattgacgc aaatccactc tcactcatct gacttttctt
      721 attcggtatc acttctctgt cacatccaac cccaaaagcc acgtatccaa ttcttttttt
      781 aattcgtctg cagattcctt aaacgtctct cgtaaatgat tcgttaactc atcattttga
      841 ctttcttgct tcagcaaatt ccgatattta tattttgtat gtctagcaat tatcgaccaa
      901 ttagaaggct cagctatcaa accatcaata actattttat caataggttt tatatcaatc
      961 ggcaaaaaat gcgggcttgc aaaactatct aagctttcct gaaccatcgc atgccaatcc
     1021 gttgctttgc cacgtcttag ctgcatttct aaccgccacc acgtatcgat ttcttttggc
     1081 acgattactt tttttcgttc ctgctctagc tttttgttgt acagtcgcac ttggcgctca
     1141 ctggcacgac tgccccagta cgctgtttct agcttgccag aacggccgta gattggctta
     1201 aaagaaatcg ggtctacaat acgatactga gtaataaagt catccggcac atctacaata
     1261 tcgcaggcaa tatccgcccg ggaaaaatgc ggatctaaaa ataggtcatg aatgaatcct
     1321 ttcatggaac tagctaaaaa ctggcctatc ttattcggat taaaatcaat acgacctttt
     1381 ccttcatgaa atttaagtat ttcgatatac gcaatatctt ctccatattg atcgaataat
     1441 tgccagccgt ttatcccaac tgatttcaaa tatccctgat tttcgttcaa acgcattaat
     1501 tgctcgaaat cgacaaaaac aactccattt ttcgtccaat aagctatggt atcattcagt
     1561 tttccgacaa ttgtaattcg atcaatcgac caatttaatt ttaggggggt ggtcgtacct
     1621 tgcacactta accgcctgtt agaaatacgg ttaagttttt cgagctgatt tatcgttgtt
     1681 cttttttctg cccctcgacc ttcaattttt gattgaattt cactcaactg attttcattt
     1741 gccattttcg tcctccaaac gaaaaaagag acttttggaa agaatttcca gagttcacgt
     1801 aaccctaaaa attcatatcc aaaaatctct agcttgaaga aacctaaaaa tattcgtata
     1861 atgaacctga gttacggagc taggtgaagt agtttccgta aatagtcgag agtgttagcg
     1921 cactgctcgg cttttatttt gctctttttt ctcgttttct ttgattatag cactcctcct
//
LOCUS       DACBZK010000186         1969 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.195, whole genome shotgun sequence.
ACCESSION   DACBZK010000186 DACBZK010000000
VERSION     DACBZK010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.195"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(59..238)
                     /gene="rpmF"
                     /locus_tag="IVD66_002905"
     CDS             complement(59..238)
                     /gene="rpmF"
                     /locus_tag="IVD66_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAP6147061.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(296..865)
                     /locus_tag="IVD66_002906"
     CDS             complement(296..865)
                     /locus_tag="IVD66_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HAP6147062.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1051..1953
                     /locus_tag="IVD66_002907"
     CDS             1051..1953
                     /locus_tag="IVD66_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP6147063.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
BASE COUNT          584 a          419 c          332 g          634 t
ORIGIN      
        1 ataaacctca aggctccatg gttagccttg aggttttaca ttttctaatt aaaatgtatt
       61 aagcttcttt tgacattacg tccttaccat catagtaacc acaatttgca catacgtgat
      121 ggcttttttt catttcacca cagtttggac attcgtttaa ccctttgatt gtcaatttgt
      181 agtgtgtacg acgttttgct tttttagctt ttgatgttct tctagctggt actgccattt
      241 tgctacacct ccttgtaaag tcttgtatct aaattagaca caatatattc caatcttact
      301 tgttatcgtc gtcttttgat ttagaatcaa aaagttcaga tagttttgca agacgaggat
      361 caattttatt ctcggcttct tccatttttc tgcgctggta ttcttcttcg gaaacaactt
      421 cccaatcatt gccttttgga agttctgttg ctgcttcctc ttcttttgtc aatacccgca
      481 ttggaatcgc caataagatg ttgtcttcaa tcgactctgc taaattcaat aatggacctt
      541 caattagcaa aatctcatct gcagacattt gttcatctct actttggaat tgttcttctg
      601 tcatgaatac ttcgtctaca gaaaaatcca tgggcagttc aacaggttct agtgaacgtg
      661 ttgaaggaac tgtcaaagtc gtctgcacag tgtaatgaac gatatagcct ttcttatcaa
      721 ctgagaccaa accttcgact tccactggcg caacatcaag tattaaattg tctcgcttca
      781 tgagagcggc tttcaagtcg agcgtctcat gaaaagttaa cggtgtctcc tggtattttc
      841 tcaattccaa taaagaccat ttcatttttc atcactccta agcaacaaaa gcaattatac
      901 agggcaaaaa gcatgttgtc aatgaaattt tcttgacacc ttgcagttca taaaaaaaca
      961 gaaaaatctt tattagaaag cctctgtttg ctatcatcct cagaatcatt tacaataatc
     1021 attattccat taaaggagcg gatgatcttc atgaacacga aagatatcga atactatgtc
     1081 caaatcgtca aacaaaaaaa ttttacgaaa gtggctaatt atttccgtgt gagccaacct
     1141 actattacat atgcattaca acgtcttgaa aaagagtttg acaccgtact tattacaaga
     1201 gatcgatcgc atcacgaatt aatcgtcacg ccttctggaa agcagctgtt tctccatgca
     1261 caaaccattc tccaagagat ttctactgca agagctgaaa tcactcagtt gcaaaagaaa
     1321 aagcttcgtt ttggcatgcc tcctattatc ggcaatgaat actttcctaa actgtcaagt
     1381 tactttatca agcatgaatt gatgaatcaa attgagatta ccgatggagg ctctcgggac
     1441 ttatacggga tgatccgaca agggaggatc gatttagctg tattaggctc aacacagcca
     1501 atcgtggatc aatatttaga aacagagtta cttttggaca aacgtttcat gatcgtcgtg
     1561 ccacctacac atcctctttc caagcaggat actgtctctt tcaaagatat agcagatgaa
     1621 cagtttgtac tattgaacga acattatgtc caccccgcag cattcactaa gctttctaaa
     1681 caaacacata ctcatccaaa agttgtttat caaagcaatg acttgacgat tttaaagagt
     1741 atggtccgag aaaatgtggg tatcggtttt ttggcagaga ttgctgtcca tcctgaagat
     1801 catttagttt gcctccctct ttcagatgaa gttcagcctc gcttcttgat ttcattggca
     1861 aaacgaacac agcagatcgt cacgcctctt caagaacaag tagtccaagt tatccatgaa
     1921 ttcgttacag cacaaaaaaa cagctcttcg taaaagaaga gctgttttt
//
LOCUS       DACBZK010000187         1833 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.196, whole genome shotgun sequence.
ACCESSION   DACBZK010000187 DACBZK010000000
VERSION     DACBZK010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1833
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.196"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            486..>1833
                     /gene="ltrA"
                     /locus_tag="IVD66_002908"
     CDS             486..>1833
                     /gene="ltrA"
                     /locus_tag="IVD66_002908"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP6147064.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQY"
BASE COUNT          710 a          284 c          394 g          445 t
ORIGIN      
        1 ataagtcggg tgtccaaaaa aacttaatat ggtgagtatg tacaaacgta ctgacgaact
       61 agcgaatgta ctgtccgaaa ggcatagctc ctagaaatgg gagagacagt gagcaaaaaa
      121 tcactcattg tgctaacttg tggttgagta aaagtcgttg ttatgaaaga ccatgctgcg
      181 ttacaggcgt aggagaagtt agggggcaaa agctagcatc taagttaagg catgtggata
      241 gatataaggg aacaggggaa gccatcaaca tggagagtgc atactcgatg aagtggtagt
      301 aagaaatatg tgaatgacaa ataacttact ttagtgatgg tgaaagtaga gtcacgactg
      361 atgaaggttc tgtaatggaa ctggaggaac aggctcgatt cgtctgtaaa agtcatgaaa
      421 cccgttcaac catgggattc tcgtatgact aaaaaggtca cgagccaatt ggagcgtgat
      481 aaaccatgac aaaagaaaca agtccaaaag ataggaagtt gcggcatgca gaatattatg
      541 gcatgacgga aatcttcgat aagatatact ccaaaagttt gaagggagat aatttcaaga
      601 atctaatgca gattatcatt tctgataaca acattgtcct agcatatcgt aatatcaaga
      661 gaaatcacgg tagtgtgaca agaggagaag atggagtaac gattaaagat attgaaaatc
      721 tcaaccgtaa tgaattcgta gaaattgtta ggaagcgatt cgcacattat aaccctcgga
      781 aagtaaggcg tgtagaaatt cctaaatata atggtaaatt aagaccgttg ggtattccat
      841 caatatggga tagaatcgcg cagcaatgca tcttacaagt attagaacca atatgtgaag
      901 caaaattcaa taatcacagc tatggtttcc gcccaaatag atcagcagaa cacgcaatag
      961 cagattgtat ggcccgaatg aatcaaagtc acatggaata tgtggtagat gtagatatca
     1021 aaggtttctt cgacgaagtc aatcatacta aactcatgag acaaatctgg tctatgggta
     1081 tacgagacaa acagcttctc ttaatcatta ggaaaatgtt aagagcaccc gtagtacttc
     1141 caaatgggaa gttgatatac ccaacaaaag gaacaccaca aggcggaata cttagcccat
     1201 tacttgcgaa catcaatctc aacgaatttg actggtggat agcaaatcag tgggaggaaa
     1261 aagatgccaa agagctaaaa catcatttta ggaaaaatgg agcttgggat aaaggtaata
     1321 tctatcacaa gctcagaaag agtacaactc taaaagaaat atacctagtg agatacgcag
     1381 atgattttaa aattttctgt agaaattata atgaagcgaa aaaagttttc tatgcaacta
     1441 aaatgtggtt acaggagcgt ctaaagttac caatatctga agaaaagtca aaaatcacaa
     1501 atctttcaaa agaagaaagt gaatttttag gctttacgat gaaattagtg accaaaggta
     1561 acaaaaaggt tgttaatacg catataggta caaaagcaca aagcatgatt aaagtgaaac
     1621 taaaaaaaca aatcaaacga attcaaaaaa gtcctaatag caaagatacc tttatctata
     1681 ttggagtcta taacagtatg gttattggga ttcataatta cttcaaaatt gcgactcatt
     1741 gtagtgtagc aatgcgaaaa attgcaagag aactcagacc aagttttgaa atacgactac
     1801 gagaacaagg aatctcaaaa gaaggacaat acg
//
LOCUS       DACBZK010000188         1761 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.197, whole genome shotgun sequence.
ACCESSION   DACBZK010000188 DACBZK010000000
VERSION     DACBZK010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1761
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.197"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(14..376)
                     /locus_tag="IVD66_002909"
     CDS             complement(14..376)
                     /locus_tag="IVD66_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147065.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAEMGKALRKH
                     FGFESFDDFERWLSSISDDQQHEKSVDNEWLADEKSAPSERDYPNESDGLLGVIPSKK
                     SQMSESKFTSMFNDVSLR"
     gene            complement(380..697)
                     /locus_tag="IVD66_002910"
     CDS             complement(380..697)
                     /locus_tag="IVD66_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147066.1"
                     /translation="MDKIDLREETVDRIELMYERLADYLNLPDEDNYSEMLERMMDVL
                     NSTINVGLANSSLITDKFVYGKIAETEDESEKEFWLNILTYVMQLNQIGVIYRNKSKG
                     KEL"
     gene            complement(798..1031)
                     /locus_tag="IVD66_002911"
     CDS             complement(798..1031)
                     /locus_tag="IVD66_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147067.1"
                     /translation="MTEKQKYFGKKNWLVNLTGDYVVVVFLDSKKMSGKLLDVTQYEL
                     ILKNNKIDSPIIIPKHAVKYIYAVAESSGEAND"
     gene            complement(1028..>1761)
                     /locus_tag="IVD66_002912"
     CDS             complement(1028..>1761)
                     /locus_tag="IVD66_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAP6147068.1"
                     /translation="NGWQLLDQHEENIAYIEILKWQEGKGRIDFNPNKISQFLASSMK
                     NFIHDLFIEPHFSRADIACDIIDVPDEFITQYRVVDPVSFKPIYGRNGKLETAYWGSR
                     SSERQIRMYNKKLEQEKKRKIVPKEIVSWWRLELQLRRGKATDWHAMVYESLDSFASP
                     HYLPADTSVADKMMITALTTEHDYWGQINRKTKYKYRNLLKQESQNDELTNHLRETFA
                     ESADDLKKELDTWLLGLDVTEEEEK"
BASE COUNT          510 a          390 c          220 g          641 t
ORIGIN      
        1 gcaaaataat cgcttatcgt aaactcacgt cattaaacat tgacgtaaat ttactctcac
       61 tcatctgact ttttttactc ggtatcactc cgagtaagcc gtcagattca ttgggataat
      121 ctcgttcgct tggcgctgat ttttcatcag caagccactc attatccact gatttttcgt
      181 gttgctgatc gtcagaaatt gacgataacc accgctcaaa atcatcaaaa gattcaaatc
      241 caaaatgctt ccgaagtgcc ttacccattt cagcattttc cttctcaatc aatcgttttt
      301 tctgttgacg aagttttgcc tgttcttttt tcaatttttc ttcttgtgct ttaatatctg
      361 ctaaagtcat tcccaagatt tacagctcct tgccttttga tttatttcga taaataacac
      421 caatttgatt taattgcata acataagtta aaatattcag ccaaaattcc ttttcagatt
      481 catcttctgt ttcggctatt ttaccgtaaa caaatttatc agtaatcaaa gaagaatttg
      541 ctaggcctac attgattgta gaattgagaa cgtccatcat tctctcaagc atttcactat
      601 aattatcttc atccggcaaa ttcaaataat cagctaatcg ttcatacatc aattcaattc
      661 tatcaactgt ctcttctctt aaatcaattt tatccatgtt acacctcatt tccaaaactg
      721 ccaccatttc cgattcttta attttcgata cacctaattc atcagcaaga ttttttatgg
      781 tcatcttttc tgacaaatca gtcattagct tctccactac tttcagctac cgcataaata
      841 tatttaacgg cgtgcttagg gataataatc ggagagtcaa ttttattatt tttcaaaatc
      901 aattcatatt gcgttacatc aagtaactta ccggacattt ttttgctatc caaaaaaaca
      961 accacaacgt aatcacctgt taaatttacc aaccaatttt tcttaccaaa atacttttgt
     1021 ttttctgtca tttttcttcc tcctctgtta cgtctagccc tagaagccat gtgtctaatt
     1081 ctttttttaa atcgtctgcc gattctgcaa aggtttctcg taaatgattc gtcaattcat
     1141 cattttgact ttcttgcttc agcaaatttc gatatttata ttttgtcttt cgattaattt
     1201 gcccccaata atcatgttct gttgttaaag cagtaatcat cattttgtca gctacacttg
     1261 tatcagcagg caagtaatga ggactagcaa aactatctaa gctttcataa accatagcat
     1321 gccaatcagt cgctttccct cgtcttaatt gtaattctaa ccgccaccaa ctcacgattt
     1381 cttttggcac aatttttctt ttcttctctt gttccagttt tttattatac atccgaattt
     1441 gacgttcaga agagcgagat ccccaatatg ccgtctctaa ttttccattc cgtccataaa
     1501 taggcttaaa agaaactgga tcaactaccc gatattgtgt aataaactca tcaggtacat
     1561 cgataatgtc gcaagcaata tctgcacgtg aaaagtgagg ttcgataaac aaatcatgaa
     1621 taaaattttt catggaacta gctaagaatt gactaatctt attcggattg aagtctatac
     1681 gccctttccc ctcttgccat tttaaaattt caatataagc aatattctct tcatgttggt
     1741 ctaacaactg ccaaccatta t
//
LOCUS       DACBZK010000189         1735 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.198, whole genome shotgun sequence.
ACCESSION   DACBZK010000189 DACBZK010000000
VERSION     DACBZK010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.198"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            174..596
                     /locus_tag="IVD66_002913"
     CDS             174..596
                     /locus_tag="IVD66_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147069.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRDGIAIGNPTNDLTVTENYLIVSPLLALAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            606..809
                     /locus_tag="IVD66_002914"
     CDS             606..809
                     /locus_tag="IVD66_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147070.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            1020..1604
                     /locus_tag="IVD66_002915"
     CDS             1020..1604
                     /locus_tag="IVD66_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6147071.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT          613 a          238 c          309 g          575 t
ORIGIN      
        1 tcacttttct ttttaaatgg caatattttt tgtaaataaa tgtcaatcaa gaaaatttaa
       61 acgattatga cattaaaaat atattttatg aattttctag tatataactt gatttatctg
      121 ttaagattta ttaagaaaac gttttcttag ttttgatttc gaggtgatag acaatgaaaa
      181 ataagtttat tttatcttta ggtattttaa ctattggaat tagtgtaact ggaactacaa
      241 ttcctacatt tgctgatagt acaaatgaac caactactgt agtagataat aaccaagaat
      301 taactccttt agatagggac ggaatagcca ttggtaaccc aactaacgac ttaactgtta
      361 ctgaaaatta tttaatagtt tctccattac ttgctctagc agcttctaaa acgatacgag
      421 tgacaggaac gatgattttt gataaagttg gttggccttc tagacctcct caatcacgga
      481 attggaaaga aaaaagaaat ggttattggt actatggaaa attgtattta caaagttata
      541 aatcagctgg aaacaattgg attgcgactt attcaggaac cttaactaga aagtagggat
      601 tttttatgcc agaatttgtg aacacaccaa atttttatca agatagcgat attctaagta
      661 aaattaattt accgaaagaa gaatcagctt tacaagttca gcgaacttta caggagacac
      721 aaaaaattca aaaatcaatt tctaatctag aagattctga agaaaaaaga aaaaaaagag
      781 accaaaaaac atatcaaaaa gaaaaataat gattttaaaa aaagagtgtc tagtcgacat
      841 tctttttttc taattgaaag tgttcataaa atcacccatt tctggacact ttcttttttt
      901 gctttatttt tcaaaaaaac aattcatttc atgttcataa acccataaca atatctatgt
      961 tcagttaaac tatatggata aagttatgtt acaataaaat taatgaagga gtgatttttt
     1021 tgaaaatagg atacgcccgg gtatctactg gtttacaaaa tttggattta caagaagaca
     1081 gcctaaataa atttggttgt gaaaaaattt ttactgatca tatgagtggg gcaaaaagta
     1141 atcgaccagg attagaaatg gccattgatt ttgttcgctc tggcgataca cttgtcgttt
     1201 ggcgcttaga tcgtttaggt agaaatatgg aagatttgat ttcaatcgtc aatcgactga
     1261 atgagcgtgg tgtgagtttt catagtattc aagaaaatat tacgatggac aaatcaagtt
     1321 ctacaggaca gctcatgttt catttgtttg cggcatttgc agaatttgag cgtaatttga
     1381 tcctggaacg atccgcagca ggacgagcag ctgctcgtgc aagaggacgg tttggtggtc
     1441 gtcctgaaaa attgtctgaa caagatttgg aattactgaa gactttagtg gatagcggta
     1501 cacctattaa gactattgcg gaacggtgga acgtctcaag aaccaccatt tatcgttatt
     1561 tggcaaaaat ggaggagaaa aatggaaaga caaattctca ttagtttttg tcatttaatg
     1621 ctgaaaattt ttgccattta tctagaaaag tgacaatagt atgagaattt tttgtaagtg
     1681 tctactgata acttattctc aaatgttgta aggattttat tcatttgtta atatt
//
LOCUS       DACBZK010000190         1733 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.199, whole genome shotgun sequence.
ACCESSION   DACBZK010000190 DACBZK010000000
VERSION     DACBZK010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1733
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.199"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            365..1615
                     /locus_tag="IVD66_002916"
     CDS             365..1615
                     /locus_tag="IVD66_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP6147072.1"
                     /translation="MKLFIGLDVSSQKLDTCFLTDSKEILFEGSLSNDLIGASEIKQR
                     ILEYQETFGFYQIVIGMESTSVYSFHPAMFFYLDEDLKLLPVEVTVENPYRIKQYSRM
                     FDQDKTDKIDAQIIADYLRVDLHTLSPIKEEVYVGLQRLTRSRYQLVTQMVEAKQHFL
                     ENLTYKCNTLSKELANEDNKTSIFGASIMNLLTEGITLDEFSEMPLEAAVELLQKLGK
                     GRFKNPEQLVKSIQKAVRSSYRLGKVTKNSIDLVLGIIANEIKFLKKQIKEIEKAITA
                     LLETIPEAQCLLSVPGLGAVYTAGLIAEIGQIERFDDQSKLAKYAGLTWTKNQSGNSQ
                     SENTPLNRSGNRYFRYYLIEATNRVRSTLPEFKEYYQKKRNEVPKHKHKRALVLTGRK
                     FVRLIDALLRNGQFYQPAKVVIEK"
BASE COUNT          602 a          311 c          303 g          517 t
ORIGIN      
        1 tgaaacgact tccatcgttt cagtcacccc ttagggctat tccttattaa ataactttta
       61 aaccttggct attgaatttt gttcctggat aatagactta tggaaacggt ctatcggaac
      121 actgctaatt tcctttgtag ctatgactac agcaggaagc ctgcatcccg acttattgat
      181 tatcatgcct caaactcatt agctgtaccg ttcacttctt aaactatttc tagtaggaaa
      241 tagggtggct tttaagaagt aaacaattga gtactattaa gcgagactgc ggttattcaa
      301 taagattcag ggataaactt caatagctaa gtattccaaa aaatttatga aaggaggacc
      361 ttccatgaaa ttatttattg gtttagacgt tagttctcaa aaattagata cttgtttttt
      421 aacagactcc aaagaaatct tgtttgaagg ttcacttagc aacgatttaa tcggagccag
      481 cgaaatcaaa caaagaattc tcgaatacca agaaaccttt ggtttctacc aaattgtcat
      541 aggtatggaa tcaacttctg tttatagttt ccacccagca atgtttttct acttagatga
      601 agatttgaag ctattacctg tcgaagttac tgtagaaaat ccttatagaa tcaaacagta
      661 ttcaagaatg ttcgatcagg ataaaacaga taaaattgat gcacagatca tagctgatta
      721 tctgcgagta gatctccata cattgtctcc tattaaagaa gaagtttatg ttggacttca
      781 acgactaaca agatctcgtt atcaattagt gacacaaatg gtagaagcaa aacaacattt
      841 tttagaaaat ttgacgtata aatgtaatac tttatcaaaa gaacttgcga atgaagataa
      901 taaaacttcc atattcggag cttcgattat gaatctactt acagaaggca ttaccttaga
      961 tgaattttca gaaatgcctc tggaagcggc cgttgaatta cttcaaaagc taggaaaagg
     1021 tcgattcaaa aatccagagc agcttgtcaa aagtattcaa aaagctgtac gtagttctta
     1081 tcgtttaggt aaagtaacca agaattccat tgaccttgta ttaggtataa tcgccaatga
     1141 aatcaagttt ctaaaaaaac agattaaaga aattgaaaaa gccattactg ctttacttga
     1201 aacaattcca gaagcccaat gcttattaag tgtcccagga ttaggagctg tttatactgc
     1261 gggcttaatc gctgaaattg gtcaaatcga gcgatttgat gatcaatcca aattagcgaa
     1321 gtatgctggt ctaacttgga ctaaaaatca gtcgggaaac tctcaatctg aaaacacgcc
     1381 actaaatcgt tctggaaatc gctattttcg ttactactta attgaagcca ccaatcgagt
     1441 aagaagcaca cttccagaat ttaaagagta ctaccaaaaa aagagaaatg aagtacctaa
     1501 acacaaacat aaacgagcgc tcgtcttaac cggaagaaaa tttgtacgct tgatcgatgc
     1561 gctactacgc aacggtcaat tctatcagcc agcgaaggtg gtgatagaaa aataacgtaa
     1621 agttatttgc gaaaatcttc gtgatcaacc cgaaaaaaat ttgattttgg tcgggtctag
     1681 ttcagcgcgg tctgattttt caaaatctaa ctcatattct aaaatttata tct
//
LOCUS       DACBZK010000191         1718 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.200, whole genome shotgun sequence.
ACCESSION   DACBZK010000191 DACBZK010000000
VERSION     DACBZK010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.200"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(606..962)
                     /locus_tag="IVD66_002917"
     CDS             complement(606..962)
                     /locus_tag="IVD66_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HAP6147073.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(976..1386)
                     /locus_tag="IVD66_002918"
     CDS             complement(976..1386)
                     /locus_tag="IVD66_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAP6147074.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
BASE COUNT          529 a          315 c          242 g          632 t
ORIGIN      
        1 tgtttgttgt cttgaattga atcaagacgc cctacacatt tggtttgtct tactttgttc
       61 agttttcaaa ggtctacttc atcaggagtg ttccccgatt cgtttttggc tgccgtagca
      121 acttttatat catatcagag agacaagtaa ttgtcaactc ttttttaaaa gtttttttga
      181 tttcgttttt cgaaatctta cagcaactca tttatcataa cttatcattt gttatttgtc
      241 aaggactttt ttgaagtttt tttcgataga atcaagcttc acaagtggtt cttttttaac
      301 aactcagtta tcttatcatg tcatttctaa catgtcaaca actattttat atgtttttta
      361 aaatactatt ttattgcttt gctacttaaa acaacagaaa tgaatatatc atgtaaattt
      421 acacatgtca atatattttt aactctatat ccccacctag atttgaattt tgaccacata
      481 aattgagcat gtctctatag tagaaaaata aagtcaaaaa aagaacacat aacacgcttg
      541 atgctaagtg ttcgactgtt acaactgtat gaaatgctca gtgacttgat taaaacagtt
      601 aaagtctatt tatttaagat aagctgttcc atcaactgct cattgtatcc aataaataga
      661 acttcatcga taataatcaa aggacgtctg aggagattgg tatgttgtgt gcataaaaaa
      721 atcagttgtt tttttcctac acaggaaagg tcaatcgcaa tgttgtgaaa agcctcagac
      781 caagtcgcaa atagctgttc tgcttgcact tcttcaaaac tgcataattc ttctgcttct
      841 tctgtactta gatcgcgttc ttctaagtca acaaattgat aaggcaattg atggtgttct
      901 aaccattgtt tcgccttcag acttgttaca cagtgcgctg atccatagac tttcacttcc
      961 acgaaggctc cctccctatg aatttaagat gttattgttt tgtaaataga tcagatttct
     1021 ggcaacacat cgaatttcac gagggacaaa tgaccggatc tcatcttcat taaatccgat
     1081 tagtattctt ttttcatcaa tcaaaatagg tcgtctcaat aatgaaggat attctttgaa
     1141 taagacgatc atttgcttta aagttaattc gttaaaatct atgcccagct tttcgtaaat
     1201 tttcgaccga gtggaaataa tatcttgaac tcctccttca gtcgctgcca agatcttttt
     1261 gatctcactt tctgttaacg gttcggcaaa aatattcttc tcttcaaatt caagttgatt
     1321 cgcttgcaac catgctcttg cttttctaca ggaagtacag ctaggcgaag tatatacttt
     1381 tatcattttc tcactccttt ttaattataa tccaattcta cagtaatttc ttttaaaata
     1441 ccaattatta gctaataaaa tataaaaaaa atcaaaataa ctgattattt acgtttgaat
     1501 aatgagaatt tttctatata ttctctattt tgataatagt attctcattt tcaaaataaa
     1561 taagggaggt gtgacaaaat tcttgtcaca cctccctttt ccgaataaac tgtgttccag
     1621 aaatagcttc ttcgaaaata agctgaaatt tcacaaaaat ttgagaagca attttcgtac
     1681 attccttctt ctttcttgaa actgaccact tctgtcac
//
LOCUS       DACBZK010000192         1686 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.201, whole genome shotgun sequence.
ACCESSION   DACBZK010000192 DACBZK010000000
VERSION     DACBZK010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1686
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.201"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(45..779)
                     /locus_tag="IVD66_002919"
     CDS             complement(45..779)
                     /locus_tag="IVD66_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAP6147075.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1106..1516
                     /locus_tag="IVD66_002920"
     CDS             1106..1516
                     /locus_tag="IVD66_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HAP6147076.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1509..>1686
                     /locus_tag="IVD66_002921"
     CDS             1509..>1686
                     /locus_tag="IVD66_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HAP6147077.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYN"
BASE COUNT          537 a          294 c          325 g          530 t
ORIGIN      
        1 ttggtacgca atcgctgtac caagtttttt tatttagctt ttgattaagc cataaataat
       61 aatttatata agaatactgc tacgacacca gcacagatag gtgctacaac tggtacccat
      121 gcatatcccc attgagaaga acctttatgt ttcaatggaa gaagtgcgtg tacaagacgt
      181 ggagcaaagt cgcgggctgg gtttagtcca ggacctgtag gaccaccaag tgaagcaact
      241 aatgtccata caaggaaacc aagtgctaag tgagctgtac caagattatc ttggaagaat
      301 ggtgcttttg taatacctag ggcaccaaag aataaaacga atgaaccaaa gaattcattg
      361 acgaaaccat tgaatttaga accaacgctg ttgattgttg agaatgtacc taacacatgg
      421 tttacgtctt ctgtttggtc gtagtaaggt ttgtaacaag ctactacgat caattgtcca
      481 atcgctgcac caatcaattg tgcaatgata taaggaacaa cttcagccca agggaataga
      541 ccattagatg ctaaagcaat tgtaaatgct gggttgatgt ggttaccgct gattccacca
      601 aaaatcattg ctggcatcat aaccccgaat ccatacccga cagcaatcag catccagtca
      661 ctgccatatc cttttgtacc ttttaaatct acgtttgcta cagcaccgtt acctagaacg
      721 attagtaatg ctgtaccaat catttccgcc gcaagacggg tcattagtga gtaatccata
      781 aatacctcca aaagttataa aaatgcaaaa aaaaaagaaa catcaacacg aaaagcatcg
      841 gtgcagtgtt tcgtgtcgga aggatttctg cagtcttaac aaatgtgaat aaaaaaatga
      901 attccattac ttataagaaa ccagaccaac agtaaaactc caactctttt taaaagttct
      961 ccacaaatca ccaagcttaa ctataaatat accaaaaaaa aaacgttttt tttctcaaaa
     1021 attgtatctt agaaacagca tgttttgaaa ctttcagaaa aggtttgtta gtaaaatgaa
     1081 agctatacgt aaggagtgtt gtttgatgaa attttttcaa gagtttttca ttattatttt
     1141 cttttctgta ttaggagaag gcatacggat ttttgctcat ttacctattc ctggaagtat
     1201 cttaggtatt ctttttttat ttttagcatt tgaaatgcat cttgttgatc ctgaaaaaat
     1261 cggagcaact ggtgattttt tattgaataa tctagccatt ttatttgttc ctgctggtgt
     1321 aggtttattg gaatattttg atgatattgc ttcgatatgg cctgttttac tgggagcagt
     1381 cgtcgtgtgt tccatcgtca cgatggttgc agcgggaaaa acggcagaag gtgtagaagc
     1441 tttgctgggc tatgtccgta agaaaaaagc agaaagggta tctgtaaacg aaatggagga
     1501 gaatcaaatt gactgagttt tttgtgaatc cattatttgg cttaagtttg actttaggag
     1561 tgtacgtatt atctgacaaa tttttgcgga aatataaact gcctgttttg aatcctctcg
     1621 tattatcgat tgttgttatt atcttatttt tgcatttttc tgggatcagc tataaagact
     1681 ataata
//
LOCUS       DACBZK010000193         1674 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.202, whole genome shotgun sequence.
ACCESSION   DACBZK010000193 DACBZK010000000
VERSION     DACBZK010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1674
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.202"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            43..657
                     /locus_tag="IVD66_002922"
     CDS             43..657
                     /locus_tag="IVD66_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6147078.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(822..1646)
                     /locus_tag="IVD66_002923"
     CDS             complement(822..1646)
                     /locus_tag="IVD66_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147079.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQ
                     ITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
BASE COUNT          556 a          290 c          259 g          569 t
ORIGIN      
        1 ttagggtgta ttttaaatag ttgcagaaag taggtaaaag ttttgagagt tgcatacata
       61 cgtgtctcat cgatcgatca aaatgaacaa cgccagattg aagaaatgaa aaaattcggt
      121 gcagagagaa ttttcatcga gaaacaatct ggcgcaacga ttactcatcg acctgttttc
      181 caagaagcat tagattacgt ccgagatcaa gatattttta ttgtggaagc tattgatcga
      241 cttggaagaa attatgacga gatcatcgct tcagtcaatt acttgaagaa gaaaaatgtg
      301 aagctgatca ttactagttt accgatcatg gctgaagcaa ttggcaatcc tctcctggat
      361 aaattcatta aggatctgat catccaaatt ttggccatga tcgctgaaca agaacggact
      421 gaatcgaaac gtcgccaggc acaaggaatt aagatcgcaa aagcaaacgg cgtctacaaa
      481 gggcggccca aattatacag tgcagacgca aaagatcccc aacgtcgcct tgtttacaaa
      541 agcatcgttg aagatcttaa aaatggtgtt gcgattgcta agattgctaa agactacaat
      601 gttacgagac aaaccgtgta tagaataaaa aaagacagca tggtcaatga caaatagttg
      661 atcatgctgc ttttattatc ttctcatctt taatttccta catataatta ctatctataa
      721 aattaagtct tactcagaac agataaagca taaaattcca acaaaccatt ttttacttaa
      781 ctaaataaag agtctgttaa tataatcttc acttatttac gttaatcccc tactgtattt
      841 gttggttcct tatctatatt ttctacaaaa tccttattat cttgtgattt agcttcgtat
      901 aattctttgt atgtcgacac attggttata ctaattccta tagctagttc ttgagactct
      961 acttttctct ctagctcctt tgacaaagtg atttgagatt tatttggttc cgttggagtc
     1021 aattctatag attcttcata aaaatctcta tacataaagc tatcattaat tttataaaaa
     1081 aaattaaatg tttttagcac tgccatataa cattcaaaac attcttctat agttggttta
     1141 cttccttgag gagaatgaac caatttatta cgtttttcta tgaaattttt aatttccttt
     1201 cttatttctt tcggaaactc aatattaaag taccctttaa acatgctccc taataatttg
     1261 tctacagggg gagattgtaa attctcaaat attagagtta aatcaggttt ctcttgttga
     1321 taaaattcct ttacccctat ttcacaggct gtaattatcg aaataaacct atctctagta
     1381 tttgatatat ttttacttct tttaaggagt ataagagaaa aggggatact ttcgtgtcca
     1441 tgcatgtaat taactaattg ttgagcttca gaagttatat ctctaattat atagttaacg
     1501 gaattaggaa gtgtctttaa ctctaatgaa atttctatcc aattactatc ttctaatctg
     1561 tatatgctcg aagtataatt tgattcgtca gcaagcatcg ctacatccca aacactgatc
     1621 ataaaatctt ttaaacgttc aatcatttca gcaatattgc taaaatcagc taat
//
LOCUS       DACBZK010000194         1608 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.203, whole genome shotgun sequence.
ACCESSION   DACBZK010000194 DACBZK010000000
VERSION     DACBZK010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1608
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.203"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            206..469
                     /locus_tag="IVD66_002924"
     CDS             206..469
                     /locus_tag="IVD66_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system, antitoxin component,
                     AbrB family protein"
                     /protein_id="HAP6147080.1"
                     /translation="MLVKEIEMKKWGNSQGIRFGKEELSVLGETNTENLKFEMVVTEG
                     KIVLTPKNKKPETLDELFANYEGEPLGKEDKYEWGNMQGREII"
     gene            469..804
                     /locus_tag="IVD66_002925"
     CDS             469..804
                     /locus_tag="IVD66_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP6147081.1"
                     /translation="MKKNYHDLSQGDLVYIDLNPTKGHEQRGKRPCIILSKPNKYLNY
                     MIGVAPITTKAKPFPVHVDLNGTQKIKGQILLEHHRMIDIESRGFQFVEAVPKEILEE
                     CIEKIKLFY"
     gene            878..>1608
                     /locus_tag="IVD66_002926"
     CDS             878..>1608
                     /locus_tag="IVD66_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAP6147082.1"
                     /translation="MENDTNIVMEHLKRRAKRRLFLWLFGTSAGLITILITVFVTLFL
                     ILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKL
                     LPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFP
                     NSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMSI
                     ITSNKLTEYDEFAIKHWGEGGNNNGT"
BASE COUNT          545 a          229 c          349 g          485 t
ORIGIN      
        1 ggtaaatcaa tgacgaactc agaactagaa tccattcctc aacaaaatca aggagacgct
       61 gtgatcaatt ttggctcaaa agaaaccatt cgtgttcatt ttagtccgaa caaacgtcaa
      121 ttgaaattgt ttgatggtgg aaagtaactt cttgtatttt ggtgtataca agtatatact
      181 aatgtgtgag agaaggaggg attccatgtt agtaaaagaa atcgaaatga aaaaatgggg
      241 aaattcacaa ggtattcgtt ttggaaaaga agaattgtca gttctaggag aaactaatac
      301 tgaaaattta aaattcgaaa tggtggtaac agaaggaaaa attgttttaa ctcctaaaaa
      361 taaaaagcca gaaactttag atgaattgtt cgccaattat gaaggagaac ccttaggaaa
      421 agaagacaaa tatgaatggg gaaatatgca aggtagggag atcatttaat gaaaaagaac
      481 tatcatgatt tatcgcaagg agatcttgtt tatattgatt taaatcctac caaaggacat
      541 gaacaacggg gaaaacgacc atgtattatt ttatctaaac ctaataaata tttgaactat
      601 atgattggtg tcgcaccgat aacaacaaaa gcgaagcctt ttcctgtaca tgttgatttg
      661 aatggtacgc aaaaaataaa aggacaaatt cttttggaac accatcgaat gattgacatt
      721 gagagtagag gttttcagtt tgtggaagct gtgccaaagg aaattttaga agaatgtatt
      781 gaaaaaatta aattatttta ttaaaagcag cgaagaataa ttattatttc ttcgcttttt
      841 tgttgtttaa aattaaaaag ttaggagtac tgactatatg gaaaatgata caaatatagt
      901 tatggaacat ttgaagcgtc gtgcaaagcg acgcttattt ttgtggttgt ttggtacttc
      961 tgcaggtttg attactattt tgatcactgt gttcgtaacc ctttttctaa tacttgcggc
     1021 gggttcgatt gataattcgg attccgattc aagtagtggt ggcgaagctt ttacaggaga
     1081 gtattcggaa ggcttaccga tttataaaga aatcaaagga agaggccctt tttctgatga
     1141 gattgcgcaa tatgccgtag gtgcagcagt gaaatataaa ttattaccaa gtgtgattct
     1201 ttcgcaatac ggttatgaat cagcgtttgg tacgtcggcg tccgcaagaa atgatctcaa
     1261 ctattttggg attacttggt ttgatggttg tctgtttcct aaaggaactg cacgaggaat
     1321 tggtggcatt gaagggggct ggtacatgaa gtttcccaac tcaaaagctg cattctccta
     1381 ttacggcttt atggtagcca cacaatcaaa ttttaatgca tgtgtaggaa ataaaagccc
     1441 tggcgcaagc ttattgatct taggacgagg tggttatgcc gctgcaggaa ttactgaaga
     1501 tagtccgtat tatacaggtt gtatgtcaat tatcacttct aataaattaa ccgaatatga
     1561 tgaattcgcc atcaaacatt ggggtgaagg tggcaataac aatggcac
//
LOCUS       DACBZK010000195         1545 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.204, whole genome shotgun sequence.
ACCESSION   DACBZK010000195 DACBZK010000000
VERSION     DACBZK010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1545
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.204"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(188..1207)
                     /locus_tag="IVD66_002927"
     CDS             complement(188..1207)
                     /locus_tag="IVD66_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP6147083.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RSDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(1218..1424)
                     /locus_tag="IVD66_002928"
     CDS             complement(1218..1424)
                     /locus_tag="IVD66_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAP6147084.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
BASE COUNT          432 a          321 c          265 g          527 t
ORIGIN      
        1 ggttgttgcc acataaagcc ataaacaatc aaccagtaga atgtgtggca acaaacctgt
       61 tatcgcatag cttggagtgt gactattatg ggtgatagtg aagatatgcg ataacatcac
      121 tattttatcg aatgattttt atagttgtca atatagttat gtaatgctcc tcaacgagga
      181 gctattttta tcgtttagga atatttaaat accaacgttt gtcatggaaa tcttgcgcac
      241 cgcctttagt gtttccctct ggatcattcg ttgcccgcat catgacatag actttcttat
      301 tagggaagtt acgcatgtta aaagatacat gatagccaac atttccagaa gtattataag
      361 cttgatttac atctgatcta taaattccat cagctcttac tcgagctaat tctttcccag
      421 tattgtaatc cataatgaag atatactcgt atttatagtt agcaatgtgc catccagcta
      481 catgcaaatt tgcattttcg atttctccaa actgatcaat gtgggcgtaa ttcgttccat
      541 ctgtcagtgt aggattagct gcaccagctc gtgttggatc aatgacaggc ttgttttcag
      601 aagttgttgg attttcatcg gtaaatccat gagctaaatc atatgctaat ttttctttac
      661 ttacgcccat ttcagaaaga taaccgtaag gatctgtatg atcgccccag atgttttgtg
      721 ttacccataa atgcgatttg attcccggtt ggttataagg agtgtccaac gttaatggaa
      781 taccatattt cattgctgaa tctctagcca attcaacgta tgccttgtag tttttctcaa
      841 acgttgcttt atcatgtgtg tgttgtaact caatctgcac aggactgttg gcattagcat
      901 acgaaccagc accgtactgt acataaccag gttgaccgac ttgataaaca attccgccgt
      961 ctcccacaat ataagcagta taagcgctag tccatgaacg ttgcatatac tgcgcttcat
     1021 tgcgtcctgt tgctgtttca ttagccgttt catgcagtaa aatatactga ttatttgcta
     1081 cttgtgagct accttcattt gcgcccaaat taaattcatt gttgatagta taggcaaatc
     1141 cgttaattgg caataaaaaa agagccgtta acaggctcat cgcagtaata gtaattttct
     1201 ttttcatatc tatcctccta tttatctgat gaaattttct tatacgttcg atttgataca
     1261 cctaaaatac tccctagaaa tgctccaaaa cctgtaataa tcatcaccgt tatatctgtg
     1321 taccgccagt taacaccttt tccgacaaga ccgacaaaag tcgctaaagc ggggataact
     1381 actatagcga tccatttcaa aatatcaaag gttctattgt tcatactatc cacctccctt
     1441 cattggttgg gctactttct ttttcaatcg cttgttttct tctatcaata tttctctttc
     1501 tgaaagcaag gcatcaattt gcccgtccag ttgttcaatt ttatc
//
LOCUS       DACBZK010000196         1483 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.205, whole genome shotgun sequence.
ACCESSION   DACBZK010000196 DACBZK010000000
VERSION     DACBZK010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.205"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..485
                     /locus_tag="IVD66_002929"
     CDS             <1..485
                     /locus_tag="IVD66_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6147085.1"
                     /translation="KEAIDQIKTAVLYPHNGLPILLMGVSGSGKTFLAEKIYEYAKEQ
                     QVIESNAPFIAYNCAQYFNFSINKIVENLTILDAMKVLRLVQKAVKELEKLMGIEFSN
                     NQLFLLYMHCCSMIERILRKESVDEQADIKEYIQKEGHNYEISKYPAYKTKFESTVIK
                     "
     gene            complement(692..1093)
                     /locus_tag="IVD66_002930"
     CDS             complement(692..1093)
                     /locus_tag="IVD66_002930"
                     /inference="COORDINATES: protein motif:HMM:NF013068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147086.1"
                     /translation="MSDKFSKKISSDIKEDFKAIFKTASIELAGERKQLIMDKYGEDK
                     KVATACKILDEGFEDAMQVMVLPENIRQRLRTTNVLERLNEEVRRRERVVRIFPNCDS
                     VIRIIGALLMEKDDEWTSAPRKYLEFDRNEI"
     gene            complement(1214..1297)
                     /locus_tag="IVD66_002931"
                     /pseudo
     CDS             complement(1214..1297)
                     /locus_tag="IVD66_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            1320..>1483
                     /locus_tag="IVD66_002932"
     CDS             1320..>1483
                     /locus_tag="IVD66_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP6147087.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTG"
BASE COUNT          482 a          277 c          287 g          437 t
ORIGIN      
        1 taaaggaagc gatcgatcaa atcaagacgg ctgtcttgta tcctcataac ggattaccga
       61 ttttattgat gggtgtaagc ggttcaggaa aaaccttttt ggcagaaaaa atttatgaat
      121 acgccaagga acaacaggtg atagaatcaa atgctccatt tatcgcctat aattgtgctc
      181 aatactttaa tttctcgatt aacaagatcg tagaaaattt aacgatcctt gatgcaatga
      241 aggttttgag attggtacaa aaggccgtca aagaactcga aaaactaatg gggatcgaat
      301 tttcaaacaa tcaattgttc ttgctttaca tgcactgctg ctcaatgatc gaacgtattt
      361 tacgcaaaga aagtgtagat gaacaagcag atatcaaaga atatattcaa aaagagggac
      421 ataattatga aatatcaaaa tacccggctt acaaaacgaa gtttgaaagt actgtaataa
      481 agtaagattt aaataagcat aaacaaggta agaaccatag gggctgtgtc aagtccaaaa
      541 tcttgtgtaa aaaggaaatc tcaaagtacg atgttttgcc ttgttgagcc tagctacggt
      601 ccaatatgct ggtaagaagt gtcaagagca aaaagcgaag cgtctcttga tacttctcac
      661 cagtatatta tactattggc ggcttaatgt gctaaatctc gttacgatca aattcaagat
      721 attttctagg tgcagaagtc cattcgtcat ccttttccat caataaagca ccgatgatac
      781 gaataacaga atcacaattt gggaaaattc ggacaacacg ttcacgacgg cgtacttctt
      841 catttagtct ttcaagaaca ttcgttgttc tcaatcgttg acggatattt tctggtaaaa
      901 ccattacttg catggcatct tcgaagccct catccaatat tttacaggca gttgcgactt
      961 tcttgtcttc cccatattta tccataataa gttgtttacg ttctccagcc agctcgatgc
     1021 ttgccgtttt gaagatggct ttaaagtctt ctttgatatc gcttgagatt ttcttggaga
     1081 atttgtcgga aatgttgcga aggagatgtg cttggcatct ctgctagctc gcacaaagaa
     1141 ggtattcttt cacagctttt gtgagcccta tatgcgcatc cgagatgacc atctttactc
     1201 ctgaaagacc gcgttctttc aatccgagag tgtaaaatat tttgtgtaaa tagaaaaaag
     1261 gaagtccctt cagtagaata gagttaccac aacacattca cagaaaagag gacttccata
     1321 tgaacgattt tactacagaa attctaaaga ctctagcgaa taaaggcgat ttgaatgaat
     1381 tattccgtgt ccatttggaa aaagctgtca atacgcttct caaaacggag ttaacggctt
     1441 tcctcgatta cgaaaagtac gatcgcattg gttttaacac ggg
//
LOCUS       DACBZK010000197         1475 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.206, whole genome shotgun sequence.
ACCESSION   DACBZK010000197 DACBZK010000000
VERSION     DACBZK010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1475
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.206"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            714..1046
                     /locus_tag="IVD66_002933"
     CDS             714..1046
                     /locus_tag="IVD66_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HAP6147088.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
BASE COUNT          506 a          210 c          300 g          459 t
ORIGIN      
        1 atttataagt taaaatatta tgataaaaat cacaaacgta gccttttacg tcataagtgt
       61 taaaagaaat aattaatttc aaatatagaa aagggaacgt atgtttgcat actccttttt
      121 tttgagttat aataatacgc gaagagagat aatttcatta tttaaacaag ctaaaaatct
      181 tgatattact tcttttcagg caatacgaat attattcgct tacatttttt gtataaattt
      241 aattgtctgc tatgcttgtg atgaattgat tttcgttctg cacttttgga tgataaattt
      301 ggacaattga aaatacaaaa aaaagaaagg cggtatgaac tcggaaggct ggtaaccttc
      361 gtcagcgttc atacacggca ttaagatttg gcccttaatg cgttaacctt tcagtgttac
      421 ggtattaccc gcaatggatt tagtataaca gatattcaaa agtgatacca ctttttttgg
      481 ctgtgttaag gttaaaaata cgtgatatta cgatgaatct atgcctaagc acaatgttat
      541 aaaaatgtcc gtgtggctct ttgccgtatg acgaacgctg aaattagagg gaacgcatgt
      601 ttggatgcgt tccctctttt ttgtttgtca tgaacgaaaa tcaattctct atttttgaaa
      661 aataacaaga aaaacttgtt aaaaatattt aaagaaattg ggtggtttat tttatgtcat
      721 atacaggaat tttgagtctc aaagatattt gtcactacgg taaacggtgt accgctacag
      781 agaaaatcac gaagaaacta tcaactggcc aaagtaaaac cgttgtgcag tgtaagaaat
      841 atataatcca gaaagacaaa gtctcagagg aaatgattta ttacattggg aaacaaaagc
      901 aaataatttt aaaagatcct atccccttaa aagagctata tccaacaatc aaacatgttt
      961 atgaccaaaa cggtgtactg attggtcgaa gaaaaaatgg agtcttgcgt tgtaccgcaa
     1021 aagggatggg gcgtttgatc ggctgaattg atcattctca taacttgtat tttatcgttt
     1081 ttcgcttgct tgaaaatatt gtcgagactt ctaaaggaac ttagagtcac tagaaaaata
     1141 aggagtagac ttgatctatc aacaattccc ttcggggagt gacggggtag gttttaacga
     1201 ttggtaacgt aaaaaattgg tcaatcgagt aaatgcgctt gtttggatag tggtgaaatg
     1261 aatttgtgta aataataagc gcagagtaaa caagagggaa tttagaagtt agacaagtta
     1321 gaatagcgtc tagattaatc atgagcagct actaagggat ctagactttg acgcaaactc
     1381 atggaataag gagtaggtct tctcgtaatg gggaggacgc acaagaaatt gtgtcgtgtg
     1441 ctgcagtaca tgtagatact tgcgaggacg ttgat
//
LOCUS       DACBZK010000198         1456 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.207, whole genome shotgun sequence.
ACCESSION   DACBZK010000198 DACBZK010000000
VERSION     DACBZK010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.207"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            108..1040
                     /locus_tag="IVD66_002934"
     CDS             108..1040
                     /locus_tag="IVD66_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HAP6147089.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1112..>1456
                     /locus_tag="IVD66_002935"
     CDS             1112..>1456
                     /locus_tag="IVD66_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147090.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQD"
BASE COUNT          640 a          169 c          227 g          420 t
ORIGIN      
        1 atgaaataaa tcaaaagtat gatgaaacat taaaaaatgt ctattcttca cttatcgttt
       61 caaatataga agaaacttca tcttctgaaa taaaaaataa gctttctttg ttaaaattaa
      121 aagaaaagga atatattatt gacgatgctg tttctgtccc tcttatttta aataaacgag
      181 agaaaaataa tttaaagaaa aaaatgctca ttccatttga ttcagaagtg aaaggattac
      241 tcaataaact aactatttct aatatagact cgactaggga aaaaatcata aaaatatttg
      301 ataaaattaa taatttattc aagaatgaca atgctgaatt aaggaagggt cttttagagt
      361 ttaaacttca agaactagaa cttcattact cttatttagt gaaaattacc gaagaaaaag
      421 aacaacaaaa agcaataaaa gaacagatga tagaagagga aaaagttcgt agagaaattg
      481 atcgtgaaaa gaaacgtatt gataaagaac aacgtcaatt caattctgaa atttccaaat
      541 taatcgcata tatgcaaaaa gctaatgcag atgtggaaaa agaattatat gcaaataaaa
      601 ttcaagaact ggaagaaaaa ttaaaagaat tagaagttat acgtgaaaat gtattacaaa
      661 gagaattaaa tactagagcc ggttatgtgt atgtaattag taatattggg tcttttggtg
      721 aagacatata taaaattggt atgactagaa gattagaacc tatggataga ataaaagaat
      781 tgagtagtgc atcggttcca tttgaatttg acgttcatgc gatgattttt tcagaggacg
      841 ctccgtcttt ggaaactaaa ttgcataatc attttagaaa acaagaagtt aataaaatta
      901 atcaaagaaa agaatttttc aaagtttcac tagacgaaat agagaaagtt gttttagaaa
      961 attataatgg aacagtaaca tttacaaaat tagctaaagc tgaacaatat agacgatctt
     1021 tagaattgtc aaaagattaa atatataaaa agccttcggg ctttttcttt taacaattaa
     1081 taggaacgta tattcgaaag gaatagaaat aatgtggtta gaaaaaataa atgacaaaaa
     1141 atttaagtac accgaacgtt atacggatcc cttaactgaa aaaaagagaa aagtgtccgt
     1201 tactttatct agcaattcac gccaagcttg gaatcaagct aacttacttt tgaatgaaaa
     1261 aatcgcagaa aaaataaaac gaaatgaaga attaccacta acttttggag aattaaaaac
     1321 taaatgggat gaaaaataca agccaactgt aaaagaaagt tcctatcgaa caactcaggt
     1381 ttatctatca ttaatttcaa aatatataaa agatgatgta cttgtaaaaa acgttaatag
     1441 taatcttata caagat
//
LOCUS       DACBZK010000199         1447 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.208, whole genome shotgun sequence.
ACCESSION   DACBZK010000199 DACBZK010000000
VERSION     DACBZK010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1447
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.208"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            101..1402
                     /locus_tag="IVD66_002936"
     CDS             101..1402
                     /locus_tag="IVD66_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP6147091.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          474 a          293 c          263 g          417 t
ORIGIN      
        1 gaaaatcatt ctatcggtcc cttttgagca tgaaaaaaca aaacatacag aagctccgtt
       61 agaattgaat caccacaaca caatcaaagg agcgttctgt atgcctgatc ttcatcatat
      121 caaactacta cttggaatca aagataaaaa cattttcatc acaaatgtgg aatcgaagag
      181 cattaagaat atcaagagtc ttgttgtttc tgcgacgtta agtaaagaaa ttcgtcgctg
      241 tcctttgtgt aaacagatga atcatgaagg catgatcgtt aagaacggaa agaaaaaatc
      301 gctcattcaa cttaataaat gtgcgaacca actgacttat cttgctttag cgaaacaacg
      361 ctaccactgt cgtggctgcc acacctattt tacggcgaat acctacattg tcgatagaaa
      421 ctgctttatc gctaaacaag tgcgctataa aattttagaa gagctaactg aaaaacaagc
      481 aatgacgaca attgctaagc attgcggcgt ttcttggtcg accgtttctc ggacactcgc
      541 ttctctgatc cccatgacaa aagtaaaaag aaattggtta ccgcgttgtt tattaatgga
      601 tgaatttcgt tcactgaaaa atcaagtcgg tccctactcc ttttcttgta tggatggcga
      661 tactggaaaa ttactggata ttcttccttc acggaagaaa aaggctctcg tttcttattt
      721 tatgcaattt gaacgacgcg cacgattgaa ggtaaaggtc atcgtgacgg acatgaatgt
      781 ttcttatgcc tctctgataa aggaatgttt tccaaaggca aaactcgttg tggatcgttt
      841 tcacattgtc aaacatctca ttcgtaaatt tgaggatatt cgcgtacgaa tcatgaaaag
      901 ctttgatcga aacgatccaa cacaagccaa atattatcga caattaaagg cgttgtctcg
      961 gcttctgatc aaacgacagg acaagcttgt ttatgacaaa tggaccaaat ggcgcaattt
     1021 tggttgggcg tatctcaccg aaagtgaagt ggtggatcgt ctgctttcga tctctgacga
     1081 attacgaatc gcctattttt actatcaaga aattcttcaa gcgtttcacg acaaagaggc
     1141 ggacactttc tttaaacttg taagaacgat gcccaattcc gttccaaaag aactgcattc
     1201 tataaaaaaa gcttttataa actatgaatc cggcattcgt ttagccctcg aattgcctta
     1261 ttcaaatgcc aaaatagaaa atctgcatac ccacatcaaa gcattgaaac gagtcgctta
     1321 tggctttcga agctttcgga aaatgaagac cagaattttc ttactaaata atctgattac
     1381 ctatgaatca aaaaacatct aaagtagaaa aggaattcta ccttagatgt tcttatctca
     1441 ctctatc
//
LOCUS       DACBZK010000200         1423 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.209, whole genome shotgun sequence.
ACCESSION   DACBZK010000200 DACBZK010000000
VERSION     DACBZK010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.209"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            98..1390
                     /locus_tag="IVD66_002937"
     CDS             98..1390
                     /locus_tag="IVD66_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP6147092.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
BASE COUNT          463 a          292 c          257 g          411 t
ORIGIN      
        1 acaccagcat cttttttatt ttccaaaaca tatagaaaag acaccttgaa atcctttaga
       61 attaatttgg cgaaccaacc caaaaggagg aatcaagatg tcttacactc accttatcaa
      121 agaaacatta gatattctag acttatcagt tacttttaac gaaaattgtc tcacaaaaga
      181 aaaatacaaa gggcaaatct gtcatattta tcgtggaaac ttgatttata cagcccaaga
      241 atgcatccac tgtaaacacc agattgcttc agatattgtg cgttggggta caacaaccgt
      301 ccggttgtta atgaacgatg tttctgaata ccgtacctac ctcgaattga aaaagcaacg
      361 cttcaaatgc aaagcttgtc agcggacctt tgtcgcagat acttctgttg cgaaaaaaca
      421 ttgtttcatc agtgagaaag tccgctggtc tgtcgtgact cgtctgaaaa aaaatacctc
      481 aatgacagag atcgccgctc agaaaaatct atcggtctct tctgtttacc gtattatgaa
      541 gcgattttat cgtccgttga atccttttcg gacaccgtta cctaaggtac tttgttttga
      601 tgaattcaaa tcagttcggg gtgtttcagg tgctatgagt ttcatcatga tggatggaca
      661 aacacagcgc ttattggaca ttgtcgagaa ccgacaactg ccttttttaa aacgttattt
      721 tagtcatttt tcacgagaaa ttcgtgaagc ggtcgaatgg atcgtgattg atatgtacgc
      781 tccttatgta tcgctcgtta aaaagctgtt tccaaaagca cagctgatta ttgaccggtt
      841 tcacatcgtc caacatattg gtcgtacctt tcgcaatcat cgaatcaaag aaacgaacca
      901 actattaaaa agcaaagaac aaaaacacta tcaattaggt aagcaattaa aaagatactg
      961 gaaacttctt caaaaagatg aacgcaagct tgattatact cgacgccttt ggcgacctgg
     1021 cttcaaagct catttaacag agaccgatat tgtggatcgc ttactgaaag ggagccctgc
     1081 tttgcgtgta ggctatcagt tatatcaaga ctttctttac gctgtaaagg aacgagacta
     1141 cgtatcgttt gaagaactac ttaccaataa tatcatgctt cccgaaggct atcagacgac
     1201 cttgagaacg ttccagaaat ttctgccaca aatcaaaaat gctttacaac aaagttattc
     1261 aaatggccca cttgaatgtc tgaacaacca tatcaaagtg ttaaaacgaa atgcatatgg
     1321 ctttcgtagc ttttataatt tcaaattgcg catcatgatt cgtcatggca acgcattgat
     1381 tttcaactaa aaaagatcaa gaggaactga tccacttgat ctc
//
LOCUS       DACBZK010000201         1393 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.210, whole genome shotgun sequence.
ACCESSION   DACBZK010000201 DACBZK010000000
VERSION     DACBZK010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1393
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.210"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>1393
                     /locus_tag="IVD66_002938"
     CDS             <1..>1393
                     /locus_tag="IVD66_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAP6147093.1"
                     /translation="FPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATI
                     DNLSRAERQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVK
                     YWKRGDIDTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDY
                     SKLTPNNLVELLSEIGGFNYYPDPENEFKQLNALDEFMNQLPPGNIAKKQYGATKIGS
                     DKAKGNILSTAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVV
                     EFYHKGKKFHEERVKVGYRGFCEINFDCHLEQGDHVCLKYNHQGKQYVAWYEFSQKVL
                     KDEEGKIVYRKKRGETHLPELEKEAVLTLDEKKSNLLVESIRMHYTDKPMAIFMLTPD
                     YDPSNHIIVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTV
                     TAGRNMLWDLFIQS"
BASE COUNT          487 a          227 c          275 g          404 t
ORIGIN      
        1 gttttcctgg ttatggcgga ataccaatta ctcattataa aaaatactgg tatattcaga
       61 cggatacagt aaatacttgt attgttggta cttcccgctc agggaaaggc cagatagaag
      121 ttttagcaac cattgacaat ttgtcgcgtg cagaaagaca aagttcaatg gttgttaatg
      181 atccaaaaac agaattatat gttgctagta aagatgaact agaagctaga gggtatgatg
      241 tgtatgcctt taatatcacc gatccactgc aatcaatgag tgataatcca ttggcactca
      301 ttgtgaaata ctggaagcga ggagacatag acaccgcaac acagttaacc aatactttta
      361 cgaatacgat ttattatgat gcaaatgctt cagacaataa atactttaac gaaaatgcgc
      421 agaaagctgt caatgcgctt atttttgcgt tattggaaca agcggatcaa acaggggatt
      481 actccaaatt aacaccaaat aatctcgttg aactactttc agaaattggc ggttttaatt
      541 attatccaga tcctgagaat gaattcaagc agctcaatgc cttagatgag ttcatgaatc
      601 agttaccccc tggaaatata gcaaaaaaac aatatggggc aacaaaaatt ggatctgata
      661 aagcgaaagg gaatatcttg tctacggcaa ttacaggatt gaatccattt accctaacga
      721 aaattgcgaa gatgacttct caatcgacca ttgattacaa gtccattggt tttccgaagt
      781 atttggatct caaattacat gaaagcctat taaatcaacg cattgtcgtg gaattttatc
      841 ataagggaaa gaaatttcac gaggaacgag tcaaagttgg ctatcgtggt ttttgtgaaa
      901 tcaactttga ttgtcattta gagcagggag atcatgtttg cttaaaatac aatcatcaag
      961 gaaaacaata tgttgcttgg tatgagtttt ctcaaaaagt attgaaagac gaagagggaa
     1021 aaatcgttta tcgaaaaaaa cgaggagaaa ctcatttgcc agaactagaa aaagaagccg
     1081 ttctaacatt agatgagaag aaaagtaacc tattagtaga gtctattcgg atgcactata
     1141 ccgataaacc aatggctatt tttatgttaa cgcctgatta tgatccatct aaccatatca
     1201 ttgttagcat ctttcttagt cagttgtata aagaattatc tacgcaatgt gttaagacta
     1261 aaggagataa atgtcaccgt aggattcatt ttattttaga tgaatttgga aatatgccac
     1321 cgatggacaa catggaagga atcatgacgg ttacggcagg tcgtaatatg ttatgggatc
     1381 tgtttattca atc
//
LOCUS       DACBZK010000202         1364 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.211, whole genome shotgun sequence.
ACCESSION   DACBZK010000202 DACBZK010000000
VERSION     DACBZK010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.211"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            82..>1364
                     /locus_tag="IVD66_002939"
     CDS             82..>1364
                     /locus_tag="IVD66_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HAP6147094.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQL"
BASE COUNT          465 a          262 c          257 g          380 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taat
//
LOCUS       DACBZK010000203         1364 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.212, whole genome shotgun sequence.
ACCESSION   DACBZK010000203 DACBZK010000000
VERSION     DACBZK010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.212"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            82..>1364
                     /locus_tag="IVD66_002940"
     CDS             82..>1364
                     /locus_tag="IVD66_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HAP6147095.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAY
                     PYFHELVEAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQL"
BASE COUNT          463 a          255 c          259 g          387 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcgaa cccattggac ggctcaaagt tattttgttc aacccagaca ttcaatcgcg
      421 aatcatgtca gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaaatt gtcaggtatc tttgaccacc gttattcgta cgttgaaaga gtttaaaagc
      541 tacttaccaa agcaatctaa gaggattctc cccagagtat tgatggttga tgaatttcgt
      601 tcgcacgctt ccatagaaga taaaatgagc tttatttgcg cagatggcga aacaggacaa
      661 ttaattgatg tcttgcctac gcgtaaattg cctcgattaa caagctattt cttaggctgc
      721 gctaatcctg aagaagtaaa atttttagtc acagacatga acgccgccta cttccagctt
      781 accaaacgta ttctgccaaa tgcgaaagta gtgattgatc ggtttcatat tatcaaacac
      841 atgaatcaag cctttaatga gttgcgtatc cgtgaaatga atgaacttcg taaagtagga
      901 cagaaaagtc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagttttc gagcaccaaa atacccattt
     1021 cttacggaag cgatgatgat tgatcgattg cttggctttt ctacgtccct gaaggaggcg
     1081 tatccctatt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacggct ttcgggaaaa gctccaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcgatgatct atccttacac caatggaaaa
     1261 atagaagcga agaataccca tataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taat
//
LOCUS       DACBZK010000204         1330 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.213, whole genome shotgun sequence.
ACCESSION   DACBZK010000204 DACBZK010000000
VERSION     DACBZK010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1330
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.213"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            48..>1330
                     /locus_tag="IVD66_002941"
     CDS             48..>1330
                     /locus_tag="IVD66_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP6147096.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTK"
BASE COUNT          417 a          289 c          265 g          359 t
ORIGIN      
        1 tcctttagaa taaagtcgac gaaaaccatt caaaggagtg tttcaagatg tcctattcag
       61 agtttaccaa agagttacta gatattctag acctaaatct tacctttcat gaagatgcct
      121 ttcgcaaaga gcgcattaat gacgaaacat gttttgtttt tgatggcaca ttgacctatc
      181 aaccagagga atgcttccat tgccactatc aaaataagca aacgatcatt aaatggggct
      241 ggaaaaaagt atccatctta ttgaatgatg tcagtaacta caagaccatt gtgcggatta
      301 acaaacagcg cttcaaatgt aaacactgtg gaaagacttt tttagcagaa gattcagtta
      361 gcgatcgtcg ctgctccatt gcccgcagag tcaaacaagc cattcttgag ctattaagtg
      421 agcctatttc tatgtctttg attgcacgta tgaagcacat ttctccgacc actgtcattc
      481 gaatacttcg cagccttcgg cctaaaaccg tttctttgaa ccagccgtta ccagaagtgg
      541 tgtgtttcga tgaattcaaa tcggtgaaaa acgtctcggg agccatgagc tttgtcatga
      601 tggacggcaa gacccatcaa ctgattgata ttgtggaaaa tcggcaactc aatcctttac
      661 gcgactattt cttgcgctac cctagaaaag tccgtgaaca agtacgtcta gtggtttcag
      721 atttctatac accctatcgc acattggtga aagagtgttt tccgaatgcc cgaatcgtcg
      781 ccgatcgctt tcatattagc caacacatcg gtcgggcctt taccaaccac cgaattcaag
      841 taatgaagac ctttaaaaaa ggggatcgtc ggtcgaagca cttaaagaaa tactggagac
      901 tacttcaaaa gaatgcgtgg gaattgaatg gtcagcatcg ctactggcgt ccgtcatttc
      961 gagatcatct gacagaagcg gagatagtcg atcggctatt atattatgat gactccttaa
     1021 agcgaggcta cgaagtctac caggtttttc tttccgctat cagaagacaa gatgttcctg
     1081 aattcgtcgc gctcctaaaa gaagactaca aggagttgcc agagcactat caaccagtgt
     1141 tcacgacctt caagaaatat cgaacagaaa tcaaacgagc gttgcgagtt ccctattcca
     1201 acggccctat agaatgtttg aacaaccata tcaaagtact aaaacgaatt gcctatggct
     1261 ttagaaactt tcaaaactac cgagaacgaa tctttttata tcgaggaaaa tatttcaaga
     1321 aaactaagaa
//
LOCUS       DACBZK010000205         1320 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.214, whole genome shotgun sequence.
ACCESSION   DACBZK010000205 DACBZK010000000
VERSION     DACBZK010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.214"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            226..495
                     /locus_tag="IVD66_002942"
     CDS             226..495
                     /locus_tag="IVD66_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP6147097.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            488..745
                     /locus_tag="IVD66_002943"
     CDS             488..745
                     /locus_tag="IVD66_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAP6147098.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
BASE COUNT          517 a          144 c          236 g          423 t
ORIGIN      
        1 acggcaaaag tgaatccagg attatgtgta ttgcgttaga tttattgatt gcccaagaaa
       61 aagcaggatt tgaggtacca gcactcaaaa agtgacgtca ctttttatcc taaaaactaa
      121 aagtgatagc acttttaatt ataagaagtt agaatattaa tcatttgctt aattgtacaa
      181 tataatgtac aattgtttta tagaaataaa taaggggtga aaggaatgga agcagtagct
      241 tattcaaatt tccgccaaaa tttacgtagt tatatgaaac aagttaatga ggatgctgaa
      301 acacttattg taacaagtaa agatgtagaa gatacagttg ttgtattatc aaaaagagat
      361 tatgattcta tgcaagaaac gttgagaaca ctttctaata attacgtcat ggaaaaaatt
      421 cgtcgaggag atgaacaatt ctccaaaggt gcatttaaaa cacatgactt aatcgaggtt
      481 gaatctgatg attaaggctt ggtctgatga tgcttgggat gattatcttt attggcatga
      541 gcaaggaaac aaaagcaata taaaaaagat taacaagtta ataaaagata tcgatcgttc
      601 cccctttgct ggattaggaa aacctgagcc attaaagcat gatttatctg gaaaatggtc
      661 cagaagaatt acagatgaac atagactgat atatagagtt gaaaatgaaa cgatatttat
      721 ttattctgca aaagatcact attaaccaat cggaagtaag gaaagggtca gaaacttaaa
      781 agtttttgat ccttatttta tttaccctag tcatttaaaa agctaatata gcttagtgtt
      841 gattgttatt aatgaatgtg tttgttacgc gtattacgga tataaggtta gtaaaatcat
      901 ttctaaagtt gaggaaaagt aaatataaat ggcttaaatt tcaacaattt gaagttgaat
      961 agatatgtta taatactatt gtagtgtggg atgttagtta ctaaaggatg acgcttatat
     1021 atatgactga atagaataag caataggttt aataatctat tttaaatttt ttgtactagt
     1081 tttagttaat tagcaaaaac aacaaaaata aacttctcat agaatttagc taaaaattaa
     1141 tgatttattt acatattaaa tttggataca gttaagtaat ttttatatat tggaggagaa
     1201 gtaatggaat ataaatttaa cttgaatttg aaagaagtac tccccactca gggaacaata
     1261 aacataaatg gtcaagataa tgatgacgat atagtaataa aaaaaataga atttattgat
//
LOCUS       DACBZK010000206         1313 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.215, whole genome shotgun sequence.
ACCESSION   DACBZK010000206 DACBZK010000000
VERSION     DACBZK010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.215"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            55..1217
                     /locus_tag="IVD66_002944"
     CDS             join(55..331,331..1217)
                     /locus_tag="IVD66_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP6147099.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQSKTSGSFKEKDNLTPEQKELLELRKRNQQLEMENDILKQAALIFGPKRQVIDANK
                     HLYPISAMCRILGLSRQSYYYQSKPKKDESELEEVVAEEFIRSRKAYGSRKIKKALSK
                     RGIQISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKTTNVLNRKFLRDNPLEAIV
                     TDLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLVKKAFSRIKQPLTEVEIFH
                     TDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAVAESTYKSLKVEFVYQYTFETLQ
                     QLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQRILDNELGCANASEAV"
BASE COUNT          474 a          233 c          264 g          342 t
ORIGIN      
        1 gacagaaaaa ttaaggtgtg tagactagaa gaaaacatac caggaggaat ttttatgtct
       61 aagagaacac gaagaacttt ttcacaagaa ttcaagcaac aaatcgtcaa tctttactta
      121 gctggaaagc cacgtgtaga aatcattcga gaatatgaac taacggcttc agcatttgac
      181 aaatgggtaa agcaatctaa aacgagtggt tcattcaaag aaaaagataa tcttacgcct
      241 gaacaaaaag aattgttaga actacgtaaa agaaaccagc aattagaaat ggaaaatgat
      301 attttaaagc aagcagcgct gatattcgga cgaagagaca agtaatcgat gcgaataagc
      361 atctttaccc tatatcagcg atgtgcagaa tattaggtct atcacgtcag tcctattatt
      421 atcaatcaaa accaaagaaa gacgaatcag aacttgaaga agtagtcgct gaagaattta
      481 tccgcagccg aaaggcctac ggctcaagaa aaataaaaaa agccttatca aaacgaggca
      541 ttcagatcag ccgacgaaaa attagtagaa tcatgaaaaa tagaggatta aaatcgagct
      601 atactgttgc ttattttaaa gtacatcatt ctacttgcaa tgaagccaaa acgacaaacg
      661 tattgaatcg taaattctta agagacaacc cattagaagc gatcgtaaca gacttgactt
      721 atgtacgagt cgggaaaaaa tggaattatg tctgtttcat tttggatctg ttcaatcgag
      781 aaattctcgg ctattcttgt ggagaacata aagatgccgt tctagtaaaa aaagcattta
      841 gccgtatcaa acaacctctg acagaggttg agatttttca tactgatcgt ggaaaagagt
      901 ttgataacca agctattgat gaattattaa caacttttga catcaatcga tcattgagtc
      961 ataaaggctg tccttttgat aatgccgtag ctgaatcaac ttataagtcg ttgaaagtag
     1021 aatttgtcta tcaatacaca tttgaaacct tacaacaatt ggatttggag ttatttgact
     1081 atgtcaattg gtggaaccac cttcggttgc acggtacact tggctacgag acaccggttg
     1141 gttaccgtaa ccagagattg gcgcagcgaa tccttgataa tgagctcgga tgtgctaacg
     1201 ctagcgaggc agtctaactt taactgttag ctcctgccga agatcgtcac atccgaggag
     1261 gctcattgtc aaggacaatc ggaatagcat acggaaagaa gttctgcacc tta
//
LOCUS       DACBZK010000207         1299 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.216, whole genome shotgun sequence.
ACCESSION   DACBZK010000207 DACBZK010000000
VERSION     DACBZK010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.216"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            853..1065
                     /locus_tag="IVD66_002945"
     CDS             853..1065
                     /locus_tag="IVD66_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147100.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
BASE COUNT          482 a          195 c          218 g          404 t
ORIGIN      
        1 atattaaata ttatacagat aataacggaa tattatcatc gaaacagcta acaaaattgt
       61 cataaaaaac gagatggttg atattagaac ttgtgttttt gtttaggtct agagataaag
      121 agagacaatt tccaaatata tgtaatgaat acaaaaagac gtttgtcgcg gattaccgtt
      181 acaaacgtct tttattgatt ttccgagatc tcatcagtcg ccatttggaa tggttcactc
      241 cttatctaga ttcgtttaat gctcggactg cttgttcgat tgtaatacca aacgcaacgt
      301 tattttcgtt ttgtgcatca atcgccataa aacggttaga agttgtatca aaagctacgc
      361 ggtattgcat atttgttttt gtaaacgtca taaaattcat ctcctttgta atgtaattta
      421 gttcttgaaa gtttccttta aactttcgaa cttataccaa gtttagcatc gtacgttttt
      481 tgatgcaatt aaaaagcatt tatcattttc cttatttatt ttttcttaaa tggtttagct
      541 attttctttt aatccgataa gtagcccaat catcaaggtt acaaatacta ttgcttgaat
      601 ataaatcata tgctcacctc tttataaata acttagcaat ataaagaaaa aaacgcacga
      661 acaacatagg aatataaaca aacgtttttg tcacaacgtc taagatcgtg ttaaaaaata
      721 gttatctaaa aagcagaaag atactcaaaa taaaaaataa aaaaatggat aaaaacgttt
      781 tcaaatacaa ggtaatttgt tattataaaa taaagaaaaa acaaaataaa aataaagaaa
      841 agagggaatg aaatggtaaa agcagaagta ggaagatctt atatatgcaa accgatcgga
      901 gtatctcatg aactaatcgg ctgtattgaa cgtacatata tcaacacggc tgtcgtgtat
      961 gttgaaagtt atgaccaacg agactatcaa cttatcaatg aaagcaagta tcgcatgctc
     1021 gtaaaattct gtgatattag cgcacctgct gaattggttt cttaaacagt atttttgaga
     1081 attcgcaaga actcccttat aatataaata aagacagaag ggagcgagaa gatatgccaa
     1141 aaagaaaaag ttcagggaaa atgggaatta ttcttgcagt gatctctgca attcctgcta
     1201 ttttagctat tgttcgtgcg atgaaggaat caagagaaag ttaagcacac attatgagcg
     1261 tcaaacaaaa aacgcatata cctgcggtgg caggttatg
//
LOCUS       DACBZK010000208         1297 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.217, whole genome shotgun sequence.
ACCESSION   DACBZK010000208 DACBZK010000000
VERSION     DACBZK010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.217"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            141..398
                     /locus_tag="IVD66_002946"
     CDS             141..398
                     /locus_tag="IVD66_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147101.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1043)
                     /locus_tag="IVD66_002947"
     CDS             complement(630..1043)
                     /locus_tag="IVD66_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HAP6147102.1"
                     /translation="MDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVLSASIPI
                     LIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEKLLYITK
                     TSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          490 a          165 c          162 g          480 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaatagat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatacc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca catataaaaa taaaaaaaca
     1141 tttgtatttt atcaaagttt tattatactt gtcaatttgt gtacatccta aaatataagc
     1201 tatttgttta cttctgtaga atatatactt tgttgttaga taagttgcac atgtttatag
     1261 aatctaaata ataaattttt atgtaccgcc cctcaaa
//
LOCUS       DACBZK010000209         1294 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.218, whole genome shotgun sequence.
ACCESSION   DACBZK010000209 DACBZK010000000
VERSION     DACBZK010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.218"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..1244
                     /locus_tag="IVD66_002948"
     CDS             <1..1244
                     /locus_tag="IVD66_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAP6147103.1"
                     /translation="ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCL
                     THYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQE
                     NYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESA
                     KTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESV
                     RLVYCFAHVRRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQ
                     QELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERN
                     IKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLS
                     AETLDQLLPWNKDVQQHFSRN"
BASE COUNT          423 a          233 c          277 g          361 t
ORIGIN      
        1 ctataacaga gaaagaacat ctccttcctt tggaagaaca attttgtgaa cattgcggtt
       61 cacagatgaa agatatcgga cggacaaaag tacgagaaga aattcgtttc catcaggcta
      121 tgttggattg tctcacccat tatcaacata cctattgttg taaaagctgc gaaaaagaag
      181 gactttcttc ttttaaaaaa gcgatcgttc ctaaaccttt gatttctaat agcttaggtt
      241 ccaatagttt agtggcggaa acgatccgga tgaaatttgg tcagaaagtt cctgcctatc
      301 ggcaagagaa ctattggaaa caaacacatg ggttggatat ttcgagagat aatatcacca
      361 attggcatat taaagcagtg caaaacgcgt tagacccttt aggagaacga ttaagagtct
      421 atcttaatca agaagagatt ctacacgggg atgaaacaag ttatcgtgtg attgaaagtg
      481 ccaaaacaga tacctattac tggcagtttt gtacaggaaa agacagtcag catcccatcg
      541 tttattatca ccacgacgaa agtcgtgctg gagatgttcc gaaaactttt ctcaaggagt
      601 ttacagggta tttacactgt gacggctata gcgggtataa tgccgtggaa agtgtacgac
      661 ttgtctattg tttcgcgcat gttcggcgga aatttttcga agcaattcca aaaggaaaga
      721 aaaacacgga tattcccgca gctcaagcag tcaaacaatt ggataaatgg tttgtcctag
      781 aaaagaaatg gaaagacttt tctcctgaga agcgattaag ctgtcggcaa caagaactgc
      841 gtccattatt tattgctttt tatgagtgga tggcaacgat agatcctgtt gcaaaatcca
      901 agttggatgc agccgttcaa tatgcgtgta aactacgaag tggttttgaa cctatttttg
      961 aagatggtcg tttagaactc acaaataatc gtgcggagcg aaatatcaaa gagctggtga
     1021 taggacggaa aaattggttg cattccacaa gtcttgaagg agcacgaact tcaggaatca
     1081 ttctgagtgt atataaaaca gcagaactta acggattgaa tcctgtaaag tatctagagt
     1141 ttctatttga taagatacca aatcttcccg tactttcagc agaaacttta gatcaactgt
     1201 tgccttggaa caaggatgta caacaacatt tttctcgtaa ctaaaaacgc caaacattcc
     1261 cgattctatt ctataggtcg ggttatttga cgta
//
LOCUS       DACBZK010000210         1265 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.220, whole genome shotgun sequence.
ACCESSION   DACBZK010000210 DACBZK010000000
VERSION     DACBZK010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1265
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.220"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            15..>1265
                     /locus_tag="IVD66_002949"
     CDS             15..>1265
                     /locus_tag="IVD66_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP6147104.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFK"
BASE COUNT          391 a          252 c          248 g          374 t
ORIGIN      
        1 taggaggatt caagatgtct catactcagc ttatcaaaga taccctaaat attctagacc
       61 taaatatcta tttcgaggaa aattgtttaa ctaaagaaaa atacaaaggg caaatttgct
      121 tgatttacaa aggaactctt ctgtacaagc cagaagagtg ttcccattgt ctttgtgtcg
      181 tcccctctag gatcattcgt tgggggacga caaccgttcg gttgttactg aatgatgtgt
      241 ctgagtatcg cacttatctg gagctgaaga aacaacgatt taaatgtaag tcttgccaaa
      301 gaacattcgt agcggatacc tctgttgctg aaaaacactg tttcattagt caaaaagttc
      361 gttggtctgt cattgctcgc ttaaaagaga atacttccat gacggaaatc gctcgtcaga
      421 aaaatatttc cacttcttcg gtctatcgtg tcatgaagcg attctaccgc ccattgaatc
      481 ctttcaaaca gactttgcca aaggtcttat gctttgatga attcaaatcg gttcgaagtg
      541 ttgccagtgc aatgagtttt atcatgatgg acggacaaag ccatgcatta ttggatattg
      601 tcgaaaatcg acgcttgcct tatttagaac gctatttttc tcggttttca ttagcgactc
      661 gtgaagccgt tcaattgatt gttattgata tgtatgcgcc ttatgtttcg ttggtgaaaa
      721 agcttttccc gaatgctcag ttgatcatcg atcgtttcca catcgtccaa catattggca
      781 gaactttctt gaatcatcga gtgaaagaaa ccacggtacg acttaaagga aattcccact
      841 ctcaacgagg gttagggaaa aaattgaagc gctattggaa actcctacaa aaagaagaag
      901 caaagttaaa ctatgaaaaa cgggtttggc gtgccagttt taaagattat ttgactgaaa
      961 gtgagattgc cgatcgactg ttagctgctt gtcccaactt acgccaaggc tatcagttat
     1021 accaagacat tctttatgcg gtaaagaaaa gagatcagtc actatttgag gattgtttaa
     1081 ctagagacat tagcggtctg ccagaaacct atacaaccac tttacgaacg tttaaaaagt
     1141 ttctgccaca gatccaaaat gcgcttcact acagctattc aaacggacca ttggaatgct
     1201 taaacaacca catcaaagta ttaaaacgca atgcgtacgg ctttcgcaac ttttacaatt
     1261 tcaaa
//
LOCUS       DACBZK010000211         1258 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.221, whole genome shotgun sequence.
ACCESSION   DACBZK010000211 DACBZK010000000
VERSION     DACBZK010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.221"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..1171)
                     /locus_tag="IVD66_002950"
     CDS             complement(<1..1171)
                     /locus_tag="IVD66_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HAP6147105.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEF"
BASE COUNT          367 a          273 c          211 g          407 t
ORIGIN      
        1 taaattctaa atattttcgt ggagaagcca gccactcagt gtctttttcc atcaaaagtg
       61 ttccaattat ccgagtgatg gaattgatat ttggaaaaat ccgaatcact cgttctctcc
      121 ggcgaatctc ttcgttcaac cgttccaaca cattggttgt acgaatcctt cggcggatat
      181 tttcaggaaa agacaaaatt tgaatagcat cttcaaagcc gttttctaaa atgtcgcaag
      241 cagcacttaa ttttgaatca caaccatatt tttccaagaa gtgctctttt ctttcacgtg
      301 tcaattcaag ttcagaggct ttaaagatac tcttcaactc gtcttttaca tcagaagaaa
      361 ctttctttgg cagcttatca aaaatatttc tcaaaaagtg ggcttggcat ctttgccagc
      421 tcgcacctaa aaagttcttg cgaacagcct taactaaccc tttgtgtgca tcagaaatga
      481 ccagttttac accgaacaaa cctcgttgaa cgaacgattg aaaaacggta tcccaattat
      541 cttccgattc gccgtcttga acatcaaaac caagaatcgt acgtcgtcca tcagaatcaa
      601 tgccgatacc aatatataca ccttttgaga caatacgatg attttccctt actttcatat
      661 acagggcatc acacatgaaa aatggatatt ccgagccttc taggctccgg tttctccact
      721 caaaaacaaa tggatccaac tgtttcatca gatttgaaac gaatgattta gaaacagtcg
      781 caccatccgt tagcagttca actgttttag ttactttgcg agtggagaca ccagaaatga
      841 ccatttcaat catggcagcg atcaaagctt tttcgcttcg ctgatatctt tcaaagatag
      901 taggactaaa cttaccgtct ctggttcgtg gaacatgaag ttctaacgta ccaattcgag
      961 ttgtaaacga acgatcgtag taaccatttc tttgtgattg ccgttcttct gaacgttcat
     1021 aggcatttgc ctgaatatat tgatttcgtt gttcttccat cagctgatta aacatgatag
     1081 tcataagtgt ttttgcggta tcattcgcac cgctttcgtt tataattgct tgaatttctt
     1141 cgctttcaaa agtaaaatgt acttgagtca ttgatatcag tcctattcga gtatgttttc
     1201 tgcaaaaaac attgtactcc taactgagat caatggcttt tttgatgctt cactttta
//
LOCUS       DACBZK010000212         1231 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.223, whole genome shotgun sequence.
ACCESSION   DACBZK010000212 DACBZK010000000
VERSION     DACBZK010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.223"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>1231
                     /locus_tag="IVD66_002951"
     rRNA            <1..>1231
                     /locus_tag="IVD66_002951"
                     /product="23S ribosomal RNA"
BASE COUNT          323 a          280 c          375 g          253 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagctg tccttagtac gagaggaccg ggatggactt accgctggtg taccagttgt
     1141 tctgccaagg gcattgctgg gtagctatgt agggaaggga taaacgctga aagcatctaa
     1201 gtgtgaagcc cacctcaaga tgagatttcc c
//
LOCUS       DACBZK010000213         1193 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.225, whole genome shotgun sequence.
ACCESSION   DACBZK010000213 DACBZK010000000
VERSION     DACBZK010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.225"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..1076
                     /locus_tag="IVD66_002952"
     CDS             <1..1076
                     /locus_tag="IVD66_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP6147106.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          331 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tct
//
LOCUS       DACBZK010000214         1173 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.226, whole genome shotgun sequence.
ACCESSION   DACBZK010000214 DACBZK010000000
VERSION     DACBZK010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.226"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            31..291
                     /locus_tag="IVD66_002953"
     CDS             31..291
                     /locus_tag="IVD66_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147107.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(653..892)
                     /locus_tag="IVD66_002954"
     CDS             complement(653..892)
                     /locus_tag="IVD66_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147108.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
BASE COUNT          416 a          164 c          218 g          375 t
ORIGIN      
        1 taatggaaaa acattaagga tggatgaaat atgaataacg aaactatcat tttaggaaaa
       61 aaatatattt gccaacctat tggcttgaaa caaaaagtgg ttggagaagt aatcagtaaa
      121 ttagaaaatt gtgttgtgat ctgcgtagac gaatatcatg acgtcgatcg caatgaaata
      181 ttagaaaaat gcggaaaagt agtggcaaaa tatactcacg tttatgagtt ggaaacaaca
      241 gaatatctat ataactatag caacaaatat gaacatactt tagtttcata aagatttaaa
      301 taaagtgcct tcaaaagcga gaagaccaag cttttgaagg cactttattt agttggcagt
      361 gattgttcat gatttttgat ttattcaaaa ggttcgccta gagaatctgt ctctgtaacg
      421 aggcctggtg gagaaactcg ataaaaacct atactgccag aactgtccta ttttcggata
      481 gacaaactag tagttttaaa aagatcatcc gatccaatca tttcaaaaaa tgcaaaactg
      541 atatcaggat catttagctc aggcttgtta tcgtaaagca tttgtaaagg ttgcatttag
      601 ttaggagtaa acgcgaaact atcatcatta tttgctgaag aagatgaaga agctaattca
      661 gagtttgttt gaaataaagg agacgtgctg acagtttctt taccctgttt tttgcagagg
      721 tagaaacttt tatatcggaa gtttctaccg gagaattttt ctcatttgta gaaattgttg
      781 aatcgatact attcgaaatt tgcgtatctg aaggtatgtt ctttgatgca gaagtcccac
      841 aagcagtaag taacaataaa tttgataaac tgataaacag aattcttttc attatgtaca
      901 cactccttat agtatcgttt agcatacacc tatgctcagt attaggcaaa atcaatgcaa
      961 aactatcaag tcttttatag tatctattag tcttagtaat acatatatgg agagggtgat
     1021 atcccagttc aaaccagata cattggttac catctgtatt aacgattatg cctctaaacg
     1081 ctttttttat gaaaaaattt ataagtgaaa acgtaggtat gatattatct agaggtaatt
     1141 tttttgggta tttaaatagt tgctaggagg ata
//
LOCUS       DACBZK010000215         1169 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.227, whole genome shotgun sequence.
ACCESSION   DACBZK010000215 DACBZK010000000
VERSION     DACBZK010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1169
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.227"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(63..626)
                     /locus_tag="IVD66_002955"
     CDS             complement(63..626)
                     /locus_tag="IVD66_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6147109.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
BASE COUNT          386 a          200 c          176 g          407 t
ORIGIN      
        1 ataataaaaa aatcactcta attctcccat aaatattata gattcctaaa gattaaaata
       61 gattattccc tattgtcttt taagtagcgg tagagtgttg ccttgctaat accagtcatt
      121 tccgtaattt cttttacgct ataaacctga cttttataca attttactgc tcgatcaaca
      181 tctttctggt tcactcgtgg acggccacct ttacgacctc tcgcacgtgc acttttcaaa
      241 ccttctttgg tacgttcaac aattaaatca cgttcgaact gactaaatgc ttggaagaca
      301 gtcatcatta agcgtccgtg aggcgtgctg gtatcgaagt tttctttcaa gctcaccagc
      361 ttaacatggt gttcttcaaa ataggtaaca aggtcaatca aatcctttgt actacgaccc
      421 aatcgagaaa aactttctac aattaccgta tctcccggac gaattttatc ttttaaacga
      481 tttagttggg gacgaaccgc tttggttccc gtcattttct cagttaggat ttcattacaa
      541 ttttgttcat tgagtaagtc taattgacga tttagttctt gtgaacgtgt actcactcgg
      601 gcataaccat aaatgtatcc actcatgctt ttcttccttt cgtactttaa ttctggcttg
      661 attgtatcat aaaagggagt tatagataca tagttaatgc aacaagttat gatacaaaat
      721 atgacctctt ttatttaata aaagaggtca tttcattttg tctcataatc gattgttttt
      781 gatacgagtg tgtatacgaa ataaacaaaa aaatcttaag taaatttcta gatacctaat
      841 ttaatcctaa ctagtgtatc ctaaagttaa taacgagttt atcacaatga aaattataaa
      901 atgctcccat attagatata acatgcaata tttgaattag aactacaaaa tttattcgtt
      961 ttataaagta aataatgttg agatactaag gaatagaata ttataaggaa ttgagctgaa
     1021 tgtattggat aaaaaaagaa taactttatt agagatggac tataaaaatg ctcgtaattt
     1081 tcttctgaag tctgaaagct atttgaatgc tcagctacca gaatatatta gttttgacga
     1141 aactttaaaa tctgctaaaa aagttttaa
//
LOCUS       DACBZK010000216         1131 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.228, whole genome shotgun sequence.
ACCESSION   DACBZK010000216 DACBZK010000000
VERSION     DACBZK010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1131
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.228"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            1..>1131
                     /locus_tag="IVD66_002956"
     CDS             1..>1131
                     /locus_tag="IVD66_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147110.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERIENKVHSLREEIKQQEKQVEKLERQEEIKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGEFEESKKYQATSEEEKAAVRELLEEA
                     VPTDFLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHS"
BASE COUNT          480 a          178 c          251 g          222 t
ORIGIN      
        1 atggcagaag aaaaagaacc actagacaat agtcgtttgg gaaaatccaa aagaaaatta
       61 gtacgattgc aaaatgaatt aaacgaacaa attgaaaaga tgtttgaaca ccagagaaag
      121 accaacggtc aaccaatgaa cgataagaga aatgggcatt cttggtttag gcaacaagag
      181 cgaatcgaaa ataaagtgca tagtctgaga gaagagatca agcaacaaga aaaacaagta
      241 gaaaaacttg aaagacaaga agagataaag gaaatgggct ataacaagta cggcggactg
      301 gatatgacga tcgagaatat tccaagaatc aaagaagaaa tcgaacgctt tgaaaaaggt
      361 gaatcgactt tttcagccgc tacgatccga aaataccaac ggaaattgga aacattagaa
      421 cagctgaaag aaagatcgga aaaaggaaaa gaaaaccttc ttcctgaagt acaagcaatc
      481 attgacagcg gacgagtgac gcaatggaaa aaaaatccga ccatttattt tctgaaaggc
      541 tatcgaaaag tcgctttaga actgaatgaa aacggggaat ttgaggaatc taaaaaatac
      601 caagccacgt cggaagagga aaaagcagct gttcgtgaat tacttgaaga ggctgtacca
      661 actgattttt tgaaggagaa agaaaacgat catttttatc gagtagaatt caacgaaaat
      721 gatccagaaa aaggattgaa aagttatggt ggggagatcg taacattcga attgatcgat
      781 caactcaaaa cgttggataa ccaatacgcc gcagaagcag gttattataa attctatttt
      841 gaagaagtga agaacggaga agtagtcgat cagatccgaa tggatctagg ggatggcgtc
      901 aacagtaatc aacccatcta tttagagtta gcaaaattgt gcgaacaagt acctgagaag
      961 gaacaaaaac aatcggtcaa aaatgaacct gtttcgaaag aacaaatgca gtcgaaagaa
     1021 acaaaaacaa aacaaaaggg ctatcaaaaa cgaacggcag aagagattaa acaagaagtt
     1081 aaatcccttt cgcaacaggc actggatgcg gtgaaaaagc atactcattc t
//
LOCUS       DACBZK010000217         1109 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.229, whole genome shotgun sequence.
ACCESSION   DACBZK010000217 DACBZK010000000
VERSION     DACBZK010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1109
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.229"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            1..1107
                     /locus_tag="IVD66_002957"
                     /pseudo
     CDS             1..1107
                     /locus_tag="IVD66_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
BASE COUNT          479 a          146 c          186 g          298 t
ORIGIN      
        1 ccaagaaact gctaaaaaat ttaatatcgg ttcaaataga actctaagta aatggataga
       61 gcaatatgaa gaaggcggtg cttcttcact tgagagccaa aaaaggggca gaaaaattag
      121 tatgaattcc aagctaaaca ttcctaaaaa acttaaagat gagtctcttg aagaagaagt
      181 tattcgttta agagcagaga acgcatattt aaaaaagtta gaaaccttga ttcaagaaca
      241 agatttgagc aagaagaaat caaggttaaa acaatccttc agctcaaaaa agaatttaaa
      301 ttgaatctat tactttcaat tgcacaatta gcgaagtcaa cttattatta ctgggtaaaa
      361 aaattagata agccagataa atatagcaag ataaagcaag aaattacagc gattgtaaaa
      421 gaatcaagaa actcttatgg ttatcgtaga gtcactttag cgttaaagat gaaaggatat
      481 acaatcaatc ataaaacagt tagaaaatta atgtcccaaa tgggacttac ctgtcaaatc
      541 cgaataaagc gatataaatc ttataaagga acagtaggaa aaattgccaa gaatgtgtta
      601 aaacgaaatt tttcagtaga tacacccaat aaaaaatggg tgacagacgt cactgaattc
      661 aagataaaag gaagaaaaat ctatctatct cctatacttg atttatttaa cggagaaata
      721 attagttata gtatatcaac tagtccaaca tataaactga ttgaagaaat gcttcaacaa
      781 gcaattaaaa aaaagggaac tgagggttca ctgattctac attcagatca aggatggcag
      841 tatcagatgc cacaatatca aaaaaaatta aaagagaata acattattca aagcatgtct
      901 agaaaaggaa attgcttaga taattctgta atagaaaatt tttttggtgt gcttaaatca
      961 gagttttttt atcgagaaaa attccgatca attgagatat ttcaaagtaa attaaatgag
     1021 tatattaggt ggtataataa caaaaggata aaactaaagt taaatggact atctccagta
     1081 gaatatcgga aacagtccat taaatagtt
//
LOCUS       DACBZK010000218         1092 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.230, whole genome shotgun sequence.
ACCESSION   DACBZK010000218 DACBZK010000000
VERSION     DACBZK010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1092
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.230"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            89..1024
                     /locus_tag="IVD66_002958"
     CDS             89..1024
                     /locus_tag="IVD66_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP6147111.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT          378 a          174 c          247 g          293 t
ORIGIN      
        1 gttataaaaa tgaacattgc atagtagaga ttctttgatt atactaattc aaggttatat
       61 gaaaaaagag aaatgagatg gatgatttat gaaactttgg atgaaaatcc ttttaggcgt
      121 cgctttagct ctgattgttg cgttagtgtt tgcagggaat tatttttata attatgctgt
      181 tgtgccttct gagaaagact ttttagacga agatacacct ggtacaacac agacatccaa
      241 agaaacggat gcacataaat ggtttagttc aaaagaaaac cgaagcgatt ggaccatcac
      301 ttcaaaagac ggtctgaaat tatcagcgat ttatcttcct gctgaaacga aaagtgaaaa
      361 aacagctctt gtggctcatg gctatatggg aaacgctgaa acgatgacca attacgcaaa
      421 gatgtttcat gatatgggtt acaatgtcct tgttcctgat gcaagaggac atggaaaaag
      481 cgaaggggat tacattggat ttggatggcc agagcgtaaa gactatgtac agtggataaa
      541 caaagtgcta gaaaacaatg gaaaatcgca agaaatcgtt ctatacggtg tcagcatggg
      601 agcagcaaca gttatgatga ctagcggaga aaaactacca gataatgtga aagcaatcat
      661 tgaagattgc ggttattctt ccgttcatga tgagcttgct tatcagctag acgatatgtt
      721 tagtcttcca gcatttccgc ttatgcaagt aacgagtcta gtgacaaaag tccgtgctgg
      781 ctactttttc ggtgaagcaa atgcagtgga acaattgaag aaaaaccagc gcccaatgct
      841 ctttatacat ggagacgaag atacatttgt accatttgaa atgttagata aggtctatcg
      901 tgcaacgaag ggaccaaaag aaaagtatgt tgtaaaagga gccgagcatg cggaagcata
      961 caagacagat cctgaaaaat atcagcaagt agtccaacaa tttttaagcc aatatgttca
     1021 ttgaacgagt ttaaaagtag gggatgaaaa gaaagaagcc tttgactgga tccagtcaaa
     1081 ggcttctttt at
//
LOCUS       DACBZK010000219         1083 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.231, whole genome shotgun sequence.
ACCESSION   DACBZK010000219 DACBZK010000000
VERSION     DACBZK010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1083
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.231"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..276
                     /locus_tag="IVD66_002959"
     CDS             <1..276
                     /locus_tag="IVD66_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAP6147112.1"
                     /translation="RNPFVSEYVKRLAKGICQLCQEKGPFIKDGVPYLHCHHIEYLSQ
                     GGKDVIENCIALCPNCHARIHELELPDDKEKLLKIVEKRENSFSKIP"
     gene            619..875
                     /locus_tag="IVD66_002960"
                     /pseudo
     CDS             619..875
                     /locus_tag="IVD66_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
BASE COUNT          375 a          164 c          198 g          346 t
ORIGIN      
        1 cgtaatccct tcgtatctga atatgttaaa cgacttgcaa aaggtatttg tcaactttgc
       61 caagaaaaag ggccatttat aaaagacggt gtaccttatt tacattgtca tcatatagaa
      121 tatttgtcgc aaggtggaaa agatgtgatt gaaaactgta tcgcgttatg tcccaattgt
      181 catgctagaa ttcatgaact tgagttacct gacgataaag aaaaattgct gaagatcgtt
      241 gaaaaaagag aaaatagctt ttctaaaata ccgtaattta tttttatagg acaaataagc
      301 taatgtgagc tatgccttct atataagact aagttctatt ataagtaacg aagtaattct
      361 cgttccttcc tgtagtaata ttttttaaat aacctatagg cttcttcaaa agtacatcct
      421 ccagtaaatt ctaagtactg gaggattctt tttctagtgt tgctttactc atgaaaaagt
      481 agttggctac ttcatcaaaa tttctgaact tttttaatgt ataataaaga gctcgatcat
      541 ttactacaag gatgctagct cctacatttt cacagttttt tagcaagtaa atttttctaa
      601 aatcacatca ggaaatgcat gagattcttt aagaaaggca attatagggc tatgattacg
      661 gttcgtgtaa gtgacgccaa aaaagaatgg ctttcttata tggctgaatt ttatgggatt
      721 actttatctg aacttctaaa aaactattcg atggaacaac tagaagatga atacaatcgt
      781 caaacggctg aaattgccca taaacattgg ataagaagtg ggaaaacaac agtattcatg
      841 gaagaatcct taatgaattt ggtgggctgg aatgacctgc cgtttaaaat tcacgcccga
      901 aattcagaag cagctctgat tggcaaatac gtgtattggt agagatagaa gataatcaat
      961 tcgttgttac cgctattcaa gtagggcacc gaagaaatgt ctatgattaa gagactgttt
     1021 atttttacaa aaaaataata actggaatct agttaaaact cttgaagtga gagatttgac
     1081 tag
//
LOCUS       DACBZK010000220         1058 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.232, whole genome shotgun sequence.
ACCESSION   DACBZK010000220 DACBZK010000000
VERSION     DACBZK010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.232"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(36..992)
                     /locus_tag="IVD66_002961"
     CDS             complement(36..992)
                     /locus_tag="IVD66_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147113.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgt
//
LOCUS       DACBZK010000221         1054 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.233, whole genome shotgun sequence.
ACCESSION   DACBZK010000221 DACBZK010000000
VERSION     DACBZK010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.233"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            67..885
                     /locus_tag="IVD66_002962"
                     /pseudo
     CDS             67..885
                     /locus_tag="IVD66_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
BASE COUNT          382 a          152 c          212 g          308 t
ORIGIN      
        1 taacagccta agatatttgg agttcagaga gggcgcgttt gattttcaaa cttcgcaaca
       61 gaaccgattt atccaagtta ccaagaatcc aaaaaaagat tcaagcaagc atatggtaag
      121 ttaaaagagg tttcatccat ggaatccatt gatgaacata cgccacttga aatccgtatc
      181 gagtacgtca aagcatttca agaattgaat cgtgcgtatg aatcgttagt gacttatgat
      241 gattacaatg atgacatggt gcaatcttca actttgaaca atcaaattca acttttggaa
      301 gaacaaattg gcgtgtacga gaccgtgaag ggttcattga tggaggaaga accagaaaaa
      361 gagggagaag atttttcaac gatcgaattt tatagtgaaa ataccactaa gttgtatgat
      421 attgattcta cttatattga tcaattacta ggaacttatg ctgcgaatag ttcagatgca
      481 cgagaagaaa ttgaaaaagc tttggctaaa ttgaataaaa cagaaggagt caaagaagtt
      541 taccgacaaa ttttaaatgc atttgatgtg gggactttag atagtaatga agatatcttt
      601 gtcattaaac gtcgctattt tacacaagca agtgataatt tgattcatgc cttttccaat
      661 gagtggtttg tttctgagaa agaattacat gcttctaatc tgcaatatat gccaggtgaa
      721 gatccaattc ctaatatgaa agcaattatc aacagtaagg attacgaagg atataaagcc
      781 aaacatccag aagcgaaacc atttaaatac ccacaagaaa tgaagcgagc atggcgtaaa
      841 atgttagatg atgagttgat tccacttgaa aatgaattga ggtaaacgag aagagttaag
      901 aaaattgtac gattcaaaga tagtagtaaa gtggaagtgt agaaaatagg gatagatgtc
      961 tttttacttg ttcacatttt ataacggagt atttaagaaa gctattgaat aatgattctt
     1021 ccatcttttt cattcattta ccggttctgt tgca
//
LOCUS       DACBZK010000222         1048 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.234, whole genome shotgun sequence.
ACCESSION   DACBZK010000222 DACBZK010000000
VERSION     DACBZK010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.234"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            4..978
                     /locus_tag="IVD66_002963"
     CDS             4..978
                     /locus_tag="IVD66_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAP6147114.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          375 a          132 c          182 g          359 t
ORIGIN      
        1 actatgtgta cgtctattac ttatgtaaca agtgatcatt attttggaag gaattttgat
       61 tatgaaatat cttacaatga agtagttact gttactccaa gaaattataa gttgaatttt
      121 cgaaaggtaa atgatttgga tactcattat gcaatgattg gtattgccgc tggtatagct
      181 gactaccctc tttattacga tgcgacaaat gaaaaaggat tgagtatggc tgggctaaat
      241 ttttctgggt atgctgatta taaagaaata caagaaggga aagacaatgt atctcctttt
      301 gaatttattc cttggatttt aggacaatgc tcaacagtag gagaagctaa aaaattgtta
      361 aaaaatatca atttagcaaa tataaattat agtgacgaac ttcctttatc ccctttacat
      421 tggctattag ctgataaaga aaaatcaatt gtcattgaaa gtatgaaaga tggacttcat
      481 atatatgata accctgtggg cgttcttacc aataatcctt catttgacta tcaattattt
      541 aatttaaaca attatcgtgt cttatcgagt gaaactccta aaaataattt ttcaaatcaa
      601 ataagtttga atgcctatag ccgcggtatg ggagggatag gcttgcctgg agatttatcc
      661 tcagtatctc gttttgttaa agcgactttt acgaagctga attctgtatc tggagattca
      721 gagtcagaaa gtattagtca atttttccat atcttaggtt cagtagaaca acaaaaaggt
      781 ttgtgtgatg taggtgatgg aaaatatgaa tatacaattt attcttcttg ttgcaatgtt
      841 gacaaaggaa tctattatta tcgaacatat gaagacagtc aaattactgc aattgatatg
      901 aataaagaag acttagatag tcataagtta attagttatc caattataga aaaacaacaa
      961 attaaatata taaattagtt aatgtgttgt gattgattat ttaatataga tataatacaa
     1021 aaaggcaaag atattttcaa aacatttt
//
LOCUS       DACBZK010000223         1003 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.235, whole genome shotgun sequence.
ACCESSION   DACBZK010000223 DACBZK010000000
VERSION     DACBZK010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.235"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            53..308
                     /locus_tag="IVD66_002964"
                     /pseudo
     CDS             53..308
                     /locus_tag="IVD66_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752209.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            372..1003
                     /locus_tag="IVD66_002965"
                     /pseudo
     CDS             372..1003
                     /locus_tag="IVD66_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          344 a          181 c          184 g          294 t
ORIGIN      
        1 gtttcaaagt tagtagagaa aatgtagtta tatatttaaa tttttaccag aaagaaatga
       61 acaccttcaa ttatctaaat ctcgaaaatg gttagatgta atcatcagga aaaacaatct
      121 taaacgaatt actattcatg gtcttagaca cacacatgct agcttgcttt tagcaagcta
      181 gtgcaaatat taaagatgtg caagagcgtt taggccactc ttctattcaa atcattatgg
      241 atctatatat tcatattaca gacaaaagaa aagaagaaac cgtagcgcaa ttcgcaaaaa
      301 atataggctc tataatttat gggactgatg aatcaaaatt gattcttcag tcccattgtt
      361 attttaggta tatgattcgt acattgaaag agttgaaaaa ctatcttccg aagccgtcaa
      421 aaaggaccct gccaaaagta ttgatggtgg atgaatttcg ttcgcacgct tcaattgtgg
      481 ataaaatgag ctttatttgt gcggatggcg agactggaaa actcattgat attttgccta
      541 cacgaaaatt gtctcgatta acacactatt ttagtcgctg tgcaaatcct gaagcggtgg
      601 aatatttagt gacagatatg aacgccgcct acttccaact gacaaaacgt gtcttaccaa
      661 atgcgaaagt cgtcattgat tgttttcata tcatcaaaca tttgaatcag gcgttcaatg
      721 attttcgtgt acaagaaatg aaaagattac accagttagg gcaacgacgg gaagccgaga
      781 aagtgaaaaa gaactggcgc tttcttctaa aaaaccgtca aaaaatcaat cactatgatt
      841 acaaaacatg gcgcagtttt cgtgcaccta aatacccgct actcactgaa gcaatgatga
      901 ttgatcgatt gctggcattt tcaacgcctt taaaggacgc ctatactttt ttccatgagc
      961 tgaccgaagc ctttagagac aaggaatcag acttattttt tac
//
LOCUS       DACBZK010000224          998 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.236, whole genome shotgun sequence.
ACCESSION   DACBZK010000224 DACBZK010000000
VERSION     DACBZK010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..998
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.236"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>998
                     /locus_tag="IVD66_002966"
     CDS             <1..>998
                     /locus_tag="IVD66_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP6147115.1"
                     /translation="NPTFVIGSSNVQTWFTLSSATIFSVVPDQPEKTGVDKNGNNVND
                     KMLQVGDTIQYRIKQKVNRLGVDLLAVYDRFELIDNLPKEVDYVDAHVESGTNKKFDV
                     SGEVTYDKTKHQVKYAAKADTLKNRMKYNGETYELVINVKVNELANQNSVAKNQGTSI
                     INKVEKDTNIITVYFPKIPVKEVQQNGKDVNGRNDGKKGTPTAPLNAGSEVQYLVTQK
                     WHTKGVDAASDHYKQFSIQDPIEARLTYKEGSAQVIDKSKGKDITSEGTLTYDSNSRT
                     LKWEASADFLSNNLLDGREIQLIFTAKTPLQSEKNIDNQAVVAVDNVSNKTNVVTIG"
BASE COUNT          389 a          159 c          198 g          252 t
ORIGIN      
        1 aatccgacgt ttgtgattgg ttcttctaat gttcaaacct ggtttacttt atcttctgcg
       61 acaatcttta gtgttgttcc tgatcaacct gaaaaaacag gggttgataa aaatggaaat
      121 aacgtgaacg ataaaatgtt gcaagtagga gacacgattc aatatcgaat caaacagaag
      181 gtgaatcgat taggagtgga tttactagcg gtttacgatc gatttgagtt aatcgataat
      241 ttaccaaaag aagtagatta cgtcgatgca cacgttgaaa gtggtacaaa taaaaaattc
      301 gatgtatctg gtgaagtgac ctatgacaaa acaaaacacc aggtaaaata tgcagcgaaa
      361 gctgatacat taaaaaatcg aatgaagtat aacggcgaaa cttacgaatt agtgatcaat
      421 gtaaaagtca atgaattggc caatcaaaat agtgtagcca aaaatcaggg aacgtcgatc
      481 attaataaag tagaaaagga tacaaatatc attaccgttt atttccctaa aattccagtg
      541 aaagaagtac aacaaaatgg aaaagatgta aacggacgaa atgacggtaa gaagggtacg
      601 ccgacagctc ctttaaacgc aggatctgaa gtacaatatc tagtcacaca aaaatggcac
      661 acaaaaggcg tagacgctgc gtcagatcac tacaaacaat ttagtattca agatccaatt
      721 gaagctcgtt tgacatataa agaaggttct gcgcaagtaa tagataagag taaaggaaaa
      781 gatattactt ctgaaggcac actaacctat gatagcaatt caagaacgct gaagtgggaa
      841 gcttccgctg acttcttaag taacaatctt ttagatggac gagaaattca gctgatattt
      901 acagctaaaa ctccattaca atcagaaaaa aatattgata accaagccgt agtagcagta
      961 gataatgttt ctaataaaac aaatgttgtg acaattgg
//
LOCUS       DACBZK010000225          990 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.237, whole genome shotgun sequence.
ACCESSION   DACBZK010000225 DACBZK010000000
VERSION     DACBZK010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..990
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.237"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>990
                     /locus_tag="IVD66_002967"
     CDS             <1..>990
                     /locus_tag="IVD66_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HAP6147116.1"
                     /translation="YFNENAQKAVNALIFALLEQADQTGDYSKLTPNNLVELLSEIGG
                     FNYQDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNILSTAITGLNPF
                     TLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHQGKKFHEERVKVGY
                     RGFCEINFDCHLEQGDHVCLKYDHRGKEYVAWYEFSQRVLKDEEGNIVYRKKRGETHL
                     PELEKEAVLTLDEDKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHIIVSIFLSQLYK
                     ELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNMLWDLFIQS"
BASE COUNT          348 a          154 c          194 g          294 t
ORIGIN      
        1 atactttaac gaaaatgcgc aaaaagctgt caatgcgctt atttttgcgt tattggaaca
       61 agcggatcag acaggggatt actccaaatt aacaccgaat aatctcgtcg aacttctttc
      121 tgagattggt ggttttaatt accaagatcc tgataatgaa ttcaagcagc tcaatgcttt
      181 agatgaattt atgaatcagt taccacctgg aaacatagca aaaaaacaat atggggcaac
      241 aaaaattggt tctgataaag cgaaaggcaa cattctatcg acagcgatca caggactaaa
      301 tccatttaca ctgacgaaaa ttgcgaaaat gacttctcaa tcaaccattg attataagtc
      361 cattggtttt ccgaagtatt tggatctcaa actacacgag agtctgttaa accagcgaat
      421 tgttgtagag ttttatcatc aaggaaaaaa atttcatgag gaacgtgtca aagtaggcta
      481 tagaggtttt tgtgaaatta actttgattg tcatttagaa cagggagatc atgtttgctt
      541 aaaatacgat catcgaggaa aagaatatgt tgcttggtat gagttttctc aaagagtatt
      601 gaaagacgaa gagggaaata tcgtttatcg aaaaaaacga ggagaaaccc atttgccaga
      661 attagaaaaa gaagccgttc taacattaga tgaggataaa agtaacttat tagtagagtc
      721 tattcggatg cactataccg ataaaccaat ggctattttt atgctcacac ctgattatga
      781 tccatctaac catatcattg ttagtatttt tcttagtcag ttgtataaag aattatctac
      841 gcaatgtgtt aagactaaag gagataaatg tcaccgtagg attcatttta ttttagatga
      901 atttgggaat atgccaccaa tggataatat ggaaggaatc atgacagtca cagctggtag
      961 aaacatgttg tgggatttgt ttatccaatc
//
LOCUS       DACBZK010000226          987 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.238, whole genome shotgun sequence.
ACCESSION   DACBZK010000226 DACBZK010000000
VERSION     DACBZK010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..987
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.238"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            48..>987
                     /locus_tag="IVD66_002968"
     CDS             48..>987
                     /locus_tag="IVD66_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP6147117.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKD"
BASE COUNT          355 a          179 c          188 g          265 t
ORIGIN      
        1 tacactcaaa atagttccga cgaaagaatt ataaggagtg agtacaaatg acctataacc
       61 atcttacacc aactgaactc gtaatgatag aagcttattt caatcaatca caacctgttt
      121 caaaagtagc caatctgtta caacgttctc gacaaactat ttataaggtc tatcgttttc
      181 ttaaatctgg tggaagcgca atgagctact ataaacaata taagaaaaac aaacgtaact
      241 gcggaagaca tccgattgtt ttacctgatg agcaacagga atacattcaa aaaaaggttg
      301 ttcaagggtg ggctcctgat gtccttattg gtcgagcaga gtttcctatt gcttgttcgg
      361 tacgcacact gtatcgaatg tttaaagata aaacctttga cactcacgat ttaccaatga
      421 agggaaaaag aaaaccaaac ggtcataaag aaaaaagagg aaaacaaggg tttcgccggt
      481 caatccgaga cagaaagaca gactataccc agtttgatca tgaatttggt cacctggaag
      541 gtgacactat cgtgggtgga aaacataaaa gcgcggtcat cacattagtt gaacggctat
      601 ctaaagtcat cattaccttg aaacccgaag gcagacaggc taaagacatt gaaaataggc
      661 tgaatcaatg gtttcgttgt gtcccaaaaa acttatttaa atccatcaca tttgattgtg
      721 gaaaagaatt ctcaaattgg aaaaagatta gtaataccaa cgatatttca atttattttg
      781 cggatccagg aacaccttct caacgaggat tgaatgaaca ttcaaatggc ttattacgta
      841 aagatggttt gtataaagct atggatttta atggtgtatc tgaaaccttt atccaatcgg
      901 tggcatcgaa acgaaatcat attcctagaa aatcattaca ctatcggaca ccaatggaag
      961 tatttttgag ttacgtcaca aaagatg
//
LOCUS       DACBZK010000227          980 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.239, whole genome shotgun sequence.
ACCESSION   DACBZK010000227 DACBZK010000000
VERSION     DACBZK010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.239"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..565
                     /locus_tag="IVD66_002969"
     CDS             <1..565
                     /locus_tag="IVD66_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147118.1"
                     /translation="EQLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETEK
                     YIMNVYLERSELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATIDD
                     YYLVFTRFLTCGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYT
                     YDDTEEIQNELDRKRMPYQRFERKKRQ"
BASE COUNT          338 a          167 c          211 g          264 t
ORIGIN      
        1 agaacaattg tatttggaaa gtgaaacgag tcaaacgaag gtcacagtca gccataatcg
       61 tttagacgtg tataaacgtc gtcctgaaac ggtaaaaaaa ggaacggagc ttctacgact
      121 agaaacagaa aaatacatca tgaatgttta cctagaaagg agtgagctgg tcgaaaactt
      181 tgtcagctac acgatttgca ggaaacacta ttactcagaa tcagaatatt attcaatttt
      241 tgagagcatg gaattaatgg aagaagaaat ggaagagcta aacagcaaag atgcgacgat
      301 agacgattat taccttgtat ttactagatt tttgacgtgt ggaacggaat ctatcgtgtt
      361 aatgggaatg gattatgaac tcgctgtacc cgaagcattt ttgagggaat atgtagaaga
      421 agtagataac ccaggcgacg actggtacac gactttaact gattttttag acacctatac
      481 ttacgacgat acagaagaaa tccaaaatga acttgaccgt aaacgaatgc catatcaacg
      541 atttgaaagg aaaaaaaggc aataatcatt tataccgaaa agtgagaatg tgtgaaataa
      601 ggacaaaaaa cctagtaact aagggaatgg ttcttatttc gcaccaatcg ctccaaccgc
      661 ccccgccgct taggtggtgc gaaataagcg ggcaacaccc gataacctaa gagaaagaag
      721 gagatccata tgaataaaat cattcctcta ttgttagtcc tatttgttgg cgaaatactt
      781 atgcgccatg ctgcagctgt gcatttaaac ttcgtagtat ttttggcaat actggtattt
      841 tgtttgatct tttggcgctt tgtattagcc cttgtgagtc tactattcaa gatgattgca
      901 gccatatttt tcatagggtt atttcgatga aaggagagag tactaatgcc aattgcaata
      961 ggaaataaac ggttacccgt
//
LOCUS       DACBZK010000228          932 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.240, whole genome shotgun sequence.
ACCESSION   DACBZK010000228 DACBZK010000000
VERSION     DACBZK010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..932
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.240"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..377
                     /locus_tag="IVD66_002970"
     CDS             <1..377
                     /locus_tag="IVD66_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147119.1"
                     /translation="RGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            637..932
                     /locus_tag="IVD66_002971"
                     /pseudo
     CDS             637..932
                     /locus_tag="IVD66_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          366 a          107 c          196 g          263 t
ORIGIN      
        1 gtagaggaag aacaaaaaaa gttggcgcac caatcagaaa gtttgataag gtttattcca
       61 ccaagcatcc tttaaaactg tcgactttgt taaatgcgac ttccagagtt ttagtagaaa
      121 agtatgagac taatatgaca agagatgaat tgcttagaaa agctttagat gagtatatta
      181 aacagaatct tacgcaagaa gataagcaag atttgtttaa tgacgtggtg aaagaactag
      241 acttgttcag agaaaaatat ccaattgttc cagaattaga tgatcgtgga gaaataataa
      301 gaactaccag tcagataaaa caagataccg aagactcact gcgcaaaggg tggggaatga
      361 ataataaagt tagataataa tcaaagaaga actaagtaac tacctttaaa cggtagttac
      421 ttagttcttc tttgatttgc atgaaataga ggggatttat ttttctggtt acgtgattaa
      481 aaaatccaaa aaatgagcat aggaacggtt atgattttag ggtgtgtttt aatgagatat
      541 tgtgatttca ttaacaagtg tatgataatc tgttgttgag ttagtaaata agtaatagag
      601 ctaactctaa aataaaacta ttaggaggag atgtaggtga aaaagtttaa aaagaaaata
      661 tatttaggat tggttgttgg ggtgagtatg tttgggttca tggctcatac taaacaagta
      721 actgcagata ctaaccaaaa agaaaggatt atgagccaat tagatgactc tcaaataagt
      781 atgtacccaa tgagctaatt gtcagtttaa aggctacaca aagaatttca acagagaaaa
      841 ataaaccgca aaatttattg ggtgtaaaag ttatggtgga aaaagatttg actcttagga
      901 caaatgaaag cgattgtaat aagcgagatc aa
//
LOCUS       DACBZK010000229          884 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.241, whole genome shotgun sequence.
ACCESSION   DACBZK010000229 DACBZK010000000
VERSION     DACBZK010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..884
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.241"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
BASE COUNT          311 a          144 c          139 g          290 t
ORIGIN      
        1 aaatgttgat cgtcagcaag gagctaaaaa atacgaatat atttcttttg tagtaaaatc
       61 ggactggttt gcatatcatt ttcttcgtaa atatcaaaat catgttaact actatcaatt
      121 actaataaaa actaccactt taagcgttaa gaactgttaa gtttagttaa gtgaggatag
      181 ttcacaaaat ccattgttaa acttcacgaa agtggtaaaa ctcaaaatgc tttatatagg
      241 attacagcat cgctctttct tcgattgcgc gttgggtaaa aaatattatg aagtaaaaat
      301 tgacgatgac acgttcctta cggctcatca gatgaaacag ctacaaaaac gaaatgatca
      361 actcgaagaa aatttaattc taaaaaagcg attgccatat tcacgcctcg ctcgacgaac
      421 tattaaaggt caagatttac ctgaagatca tcctttttag gaaattgaag ctttttatgt
      481 tgcacaatgc atttataata ctacaatgat gttttcacca gatattcttc tagggtgcgg
      541 tgtaatgaaa cagatacact tgcaaaagaa aattcaccgc gaatttacta aaattatgaa
      601 taattatgtt aatcttccga aatttttttc caaaattaag ggatcaagct ggtgttatag
      661 attgtttaag gttggcaaaa aaataacttc tttttaaaca attatagaaa accgatactc
      721 tgttaagttg gttgacacgg tgtcgatttt tatgactttc ttattctgaa acttcactaa
      781 cggacagtac ctaaaaagtc tatagtatgg acgtttacga gtactatttt atcaaaaatg
      841 ctgctcattt caacttatat gttttagtga actaccccca ctta
//
LOCUS       DACBZK010000230          881 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.242, whole genome shotgun sequence.
ACCESSION   DACBZK010000230 DACBZK010000000
VERSION     DACBZK010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..881
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.242"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            32..739
                     /locus_tag="IVD66_002972"
     CDS             32..739
                     /locus_tag="IVD66_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147120.1"
                     /translation="MNNVVYQLTMEDISRFLTNKEHLNEVIRRIQKDFSCMEEMKYFV
                     QNVEEQLYLESETSQTKVTVSNNRLDVYKRRPESLKKGAELLRLETEKYVMNVYLEKS
                     ELVENFISYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATVDDYYLVFTRFLT
                     CGTESIVLMGIDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKQMPYQRFERKKGQ"
BASE COUNT          338 a          138 c          181 g          224 t
ORIGIN      
        1 tattacacca tgaaaaagga ggacaacgaa aatgaataat gtagtttatc aactaacaat
       61 ggaagacatt tctcgttttt taacaaacaa agaacatttg aatgaagtaa tcagacggat
      121 tcaaaaagac tttagttgta tggaagaaat gaagtacttt gttcaaaacg ttgaagaaca
      181 gttatatttg gaaagcgaaa cgagtcaaac aaaggtcaca gtcagcaata atcgtttaga
      241 tgtgtataaa cgtcgtcctg aatcattaaa aaaaggagcg gagcttctac gactagaaac
      301 agaaaaatac gtcatgaatg tttacctaga aaaaagtgag ttggtcgaaa attttattag
      361 ctacacgatt tgcaggaaac actattactc agaatcagaa tattattcaa tttttgagag
      421 catggaatta atggaagaag aaatggaaga gttaaacagt aaagatgcga cggtagacga
      481 ttattacctt gtatttacta gatttttaac gtgtggaacg gaatctatcg tgctaatggg
      541 aatagattac gaactcgctg tacccgaagc gtttttgagg gaatatgtag aagaagtaga
      601 taacccaggg gatgattggt acacgacttt aactgatttt ttagacacct acacttacga
      661 cgatacagaa gaaatccaaa atgagcttga ccgtaaacaa atgccatatc aacgatttga
      721 aaggaaaaaa ggtcaataat catttatacc gaaaagtgag aatgtgtgaa ataagaacaa
      781 aaaaccttga aattaaggga atggttctta tttcgcacca atcgctccaa ccgcccccgc
      841 cgcttaggtg gtgcgaaata agcgagcaaa gcccgctaac c
//
LOCUS       DACBZK010000231          880 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.243, whole genome shotgun sequence.
ACCESSION   DACBZK010000231 DACBZK010000000
VERSION     DACBZK010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..880
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.243"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..734)
                     /locus_tag="IVD66_002973"
     CDS             complement(<1..734)
                     /locus_tag="IVD66_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAP6147121.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGT"
     gene            complement(734..871)
                     /locus_tag="IVD66_002974"
     CDS             complement(734..871)
                     /locus_tag="IVD66_002974"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147122.1"
                     /translation="MTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGG
                     K"
BASE COUNT          261 a          202 c          153 g          264 t
ORIGIN      
        1 gtgccgttgt tattgccacc ttcaccccaa tgtttgatgg cgaattcatc atattcggtt
       61 aatttattag aagtgataat tgacatacaa cctgtataat acggactatc ttccgtaatt
      121 cctgcagcgg cataaccgcc tcgtcctaag atcaataagc ttgcgccagg gcttttattt
      181 cctacacaag cattaaaatt ggattgtgtg gctaccataa agccgtaata ggaaaatgca
      241 gcttttgagt tgggaaactt catgtaccag ccaccttcaa tgccaccaat tcctcgtgca
      301 gttcctttag gaaacagaca accatcaaac caagtaatcc caaaatagtt gagatcattt
      361 cttgcggacg ccgatgtacc aaacgctgat tcgtaaccgt attgcgaaag gatcacactt
      421 ggtaataatt tatatttcac tgctgcacct acggcatatt gcgcaatctc atcagaaaaa
      481 gggcctcttc ctttgatttc tttataaatc ggtaagcctt ccgaatattc tcctgtaaaa
      541 gcttcgccac cactgcttga atctgaatcc gaattatcaa tcgagcccgc cgcaagtatt
      601 agaaataggg tcacgaacac agtgatcaaa atagtaatca aacctgcaga agtaccaaac
      661 aaccacaaaa ataagcgccg ctttgcacga cgcttaacat actgcttgat taaactttca
      721 ttttggtttt ccattatttt cctccatcaa acaattttaa ttgacgtttg ttcggactaa
      781 aatgaacacg aatggtttct tttgagccaa aattgatcac agcgtctcct tgattttgtt
      841 gaggaatgga ttctaattct gagttcgtca ttgatttacc
//
LOCUS       DACBZK010000232          839 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.244, whole genome shotgun sequence.
ACCESSION   DACBZK010000232 DACBZK010000000
VERSION     DACBZK010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..839
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.244"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..792
                     /locus_tag="IVD66_002975"
     CDS             <1..792
                     /locus_tag="IVD66_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP6147123.1"
                     /translation="FCGYSKTEPRHSFGPAIREQYLIHIVLEGEGYYSINDQKYFLKK
                     GQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYYLKEIGVGKNHLTFKVENLNSF
                     KGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSASYLNEGIITKKMNPFVRQTIEI
                     IRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISIKEYISEIKISIANDLLSSTEY
                     SIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRLGLGIINGE"
BASE COUNT          311 a          116 c          141 g          271 t
ORIGIN      
        1 ttttgtgggt attcaaaaac agaacctaga catagttttg gaccagctat tcgagaacaa
       61 tacttaatac acatagtgct agaaggtgaa ggctattatt caattaatga tcaaaaatat
      121 tttctgaaga aaggccaagg atttgttatc ccaccaggag tatctacttt ttatcaagca
      181 gatgaaaaaa atccgtggtc atatgtatgg ttgggtttaa gtggcaatct tgtagaatac
      241 tatctaaaag aaattggtgt tggaaagaat catcttacct ttaaagtcga aaatttaaat
      301 tcatttaaag gattaatttt tgaaacttta tcgtatgatc aggacaatct agtcagtgaa
      361 ttgtccagac aaaaacaagt ttataaattt ttagaactcc tcttaaattc agctagttat
      421 ctgaacgaag ggataattac taaaaagatg aatccttttg ttcgtcaaac aattgaaata
      481 atacgtgaga atgcgtatca aaaattatct gttaaagata ttgctgtcag tctatcgata
      541 cacgaaaatt atttatcacg attgtttaag aatgatatgg gaatatcaat aaaagagtat
      601 attagtgaaa tcaaaatttc tattgcaaac gatctgttat catcaactga atattcaatc
      661 cagcaaatca gtgacaagat aggattctca acagtacaat ctttttctaa agcctttaag
      721 aaagcaaatg gtgtttcacc gggagtatat cgaaaacgta gattaggtct aggaatcatt
      781 aatggtgaat aaactaaaca tttgattttg ataaatattc gttactttaa acgcttact
//
LOCUS       DACBZK010000233          819 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.245, whole genome shotgun sequence.
ACCESSION   DACBZK010000233 DACBZK010000000
VERSION     DACBZK010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.245"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..480
                     /locus_tag="IVD66_002976"
     CDS             <1..480
                     /locus_tag="IVD66_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP6147124.1"
                     /translation="IRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTVEE
                     WKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYHES
                     KSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEIS"
     gene            611..819
                     /locus_tag="IVD66_002977"
                     /pseudo
     CDS             611..819
                     /locus_tag="IVD66_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
BASE COUNT          309 a          125 c          170 g          215 t
ORIGIN      
        1 ataagagggt ttccaatatt accagtaggg tatattcaac acagacatcc gatgtgtaaa
       61 aaaagaaata ttaataaata caccgaagaa ggtagggaag ccattcataa gaagcaacaa
      121 accgtagaag aatggaagat atcgtggttg tgtagcaatc cagtgcttag taagagagca
      181 acgattgaat ttgcggacaa tcgaatttca aaattcatcg ctcaaaaggg aagatgtgca
      241 gtaacaggtg aggagcttat cttatctgaa atgcattgtc atcatattat cccttatcat
      301 gaaagcaaaa gtgatagcta tgaaaaccta gtgattgtta ctgaggaggt tcatcgggta
      361 atacacgcta cacaaagtga aacgattgag gaacttctaa aatatctaaa attaaatcca
      421 aaacaaaaag aaaaactcaa tgagttgaga ttaaaagttg gtaacgaaga aatatcttaa
      481 taaatatttg taggacggga aaacagaatg tcttttatag acgagggaac gccgtatgcg
      541 gtgaaagtcg cacgtacggt gtggactggg ggaaaagacg gagataatat caaactctta
      601 cctatcagta tcgattaatc cagattttat tgaaacggta aattatgtca caaactttca
      661 acgagaaatg cgtaaagtag aagcaatgac tgttttagct acacaatccc cacaagaaat
      721 ggtgccagaa aatatgtctt ctgataactt ctcgaaactg aagaaagtct ttgaattttc
      781 ttctacgaag atctttatgc gtatggatga atctatttt
//
LOCUS       DACBZK010000234          803 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.246, whole genome shotgun sequence.
ACCESSION   DACBZK010000234 DACBZK010000000
VERSION     DACBZK010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..803
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.246"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..672
                     /gene="tnpB"
                     /locus_tag="IVD66_002978"
     CDS             <1..672
                     /gene="tnpB"
                     /locus_tag="IVD66_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAP6147125.1"
                     /translation="SGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDN
                     NKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTD
                     FLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRK
                     IIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLH
                     SMGLA"
BASE COUNT          296 a          125 c          150 g          232 t
ORIGIN      
        1 agcggtaaat actatatttc tttgttgtgt aaagaagaaa ttatcgaatt acctaaaact
       61 aattccacaa ttggtattga cttaggtatt atggactttg cgattctttc tgatggacaa
      121 aaaattgata ataataaatt cacgtccaaa atggaaaaga aactaaagcg tgaacaacgc
      181 aaattgtcta ggcgtgcttt attggctaaa aataaaggta ccaatctatt tgaagctaaa
      241 aattatcaaa aacaaaaacg caaagtagct agattgcatg aaaaagtaat gaatcaacgt
      301 actgattttc tgaataagtt gagtacagaa atgatcaaaa atcacgatat tatctgtatt
      361 gaagacttaa acacaaaagg tatgttgcga aatcataaat tagctaaaag tatttctgat
      421 gtttcttggt caaagtttgt gactaaatta caatacaagg ctgactggta tggacgaaaa
      481 atcatcaaag tagataaatg gtttccgtct agtcagattt gttcagagtg cggacataaa
      541 gatggcaaga aatctcttga aattcgagaa tggacttgtc ctgtttgtca tactcatcat
      601 gatcgtgata tcaatgctag tatcaatatt ctgaccgaag gtctaagact acattctatg
      661 ggattggctt agatccaatc atcaagaacc gtaggaacta cggggatagc ttggtaaata
      721 agagacaccg ctgttagtaa agaaatacgc tatcaagtat gctctattcc caagaagctc
      781 ccacttcaag cgttaagaac cgt
//
LOCUS       DACBZK010000235          791 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.247, whole genome shotgun sequence.
ACCESSION   DACBZK010000235 DACBZK010000000
VERSION     DACBZK010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.247"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..782
                     /locus_tag="IVD66_002979"
     CDS             <1..782
                     /locus_tag="IVD66_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6147126.1"
                     /translation="DMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNG
                     VSLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGE
                     LISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKL
                     IKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNIDKKVSSHMLRHSHISLLTELGI
                     PLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT          340 a          107 c          102 g          242 t
ORIGIN      
        1 aagatatgct agattactac tattttgaaa aaaatttatc atataattat gtaatacatt
       61 taaaaacttt tacaggaatg atttttaaat tcgccaaccg tcgatatgga ttaaaatata
      121 atcccgtaaa tggggtttct ttagcaagaa aacctaagac aaacgaagaa ataaaaaaag
      181 aaaaagatgg ttatttatca aaagaagaag ttcaaatgat tgctagtaaa caaaaaagtt
      241 cacatcaaca gtcacgttat tctttaatta ctaaattttt gtttttaact ggactacgtt
      301 atggtgaatt gatatctttg actgaatctg attatgatgg taataaaatt acggtttctg
      361 gtacttatga ttacgagtta aaaattaaaa caacaactaa aaatacaggt tcttatagaa
      421 ccattgaatt atcaagtaat gctaaagaaa tcatagatca attaattgaa gaaaacaaat
      481 taattaagaa taataaagat aaatacattt tcatctctaa aaatggtaac ccgatatcta
      541 ttcaagcata taatcaatct ttaagagcag tatccaaaga attaaacata gataaaaaag
      601 tttcttctca catgttaagg cattcccaca tttctctact tacagaatta ggaatcccat
      661 taaaagccat tatggatcgt gtaggacatg aagattcaaa aacaacatta aagatttata
      721 ctcatacaac taaaaatatg caaaatcaac tagtagaaaa actaggaaaa atagaaattt
      781 aaattgcccc t
//
LOCUS       DACBZK010000236          751 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.248, whole genome shotgun sequence.
ACCESSION   DACBZK010000236 DACBZK010000000
VERSION     DACBZK010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..751
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.248"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            10..>751
                     /locus_tag="IVD66_002980"
     CDS             10..>751
                     /locus_tag="IVD66_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP6147127.1"
                     /translation="MNRSRQTIHKVYLFFKQGKSALEYYQQYKKNKSNCGRRPLVLPE
                     EQSEYIQRKVVQGWTPDVIVGRAAFPISCSARTIYRMFKKGLFDSSDLPMKGKRKPNG
                     HQERRGKQTFRRSIHEREKDYSQFSNEFGHLEGDTIVGLKHKSAVITLVERLSKVIIT
                     LKPCGRQAIDIEKKLNQWFESVPKNLFKSITFDCGKEFSNWKQISNVNDIAIYFADPG
                     TPSQRGLNENSNGLLRRDGLLKSMDFNSV"
BASE COUNT          254 a          131 c          149 g          217 t
ORIGIN      
        1 gcccattgct tgaatcgttc aagacaaacg atccataaag tatatctgtt cttcaagcaa
       61 ggaaaatcag ccttagaata ttatcaacag tataagaaaa acaaatcaaa ctgtggtaga
      121 cgtccgcttg ttttacccga ggaacaatca gaatatattc aaagaaaggt tgttcaagga
      181 tggacacccg atgtgattgt tggtcgtgca gcgtttccta ttagttgttc tgctcgtacc
      241 atttatcgta tgttcaaaaa ggggctattt gattcttctg acttaccgat gaaaggcaag
      301 cgtaaaccga atggacatca agaaagacgt ggaaaacaaa ctttccgccg ctctattcat
      361 gaacgtgaaa aggattatag ccaattctca aatgagtttg gtcaccttga aggtgacact
      421 atcgtaggtc tgaaacataa aagtgctgta attaccttag ttgaacgatt atcaaaagtt
      481 atcatcacat tgaaaccgtg tggtagacaa gcgattgata ttgaaaaaaa attaaatcaa
      541 tggtttgaat ctgtaccgaa aaacctattc aaatccatca cttttgattg tggaaaggaa
      601 ttttcaaatt ggaaacagat cagtaatgtc aatgatattg ccatttattt cgctgatcca
      661 ggaacgccgt ctcaaagagg cctaaacgag aattctaacg gattgttacg tagagatggt
      721 ttattgaaat ctatggattt caattcagta g
//
LOCUS       DACBZK010000237          740 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.249, whole genome shotgun sequence.
ACCESSION   DACBZK010000237 DACBZK010000000
VERSION     DACBZK010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.249"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            176..379
                     /locus_tag="IVD66_002981"
     CDS             176..379
                     /locus_tag="IVD66_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAP6147128.1"
                     /translation="MKHCVILGILGTCLAGIGTGIDVDAATYYGNGLYCNKEKCWVNW
                     GQSWSEGLKRWGDNLFGSFSGGR"
     gene            379..729
                     /locus_tag="IVD66_002982"
     CDS             379..729
                     /locus_tag="IVD66_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP6147129.1"
                     /translation="MTSINIDHTKKVIHELYNSLMTRPNQTKALLDITDVLFQVYKKI
                     DTAKYPEILVNKLVNYIYIVGFDNKIRFIDNDEKLLIELGDISKKAGINSKYKANFTD
                     KSQFYSYSETMPQR"
BASE COUNT          299 a           79 c          119 g          243 t
ORIGIN      
        1 cttccttttt tgtatggatt ttttcattta cacaaaatat tttacactct cgtcaatcat
       61 tgttatataa taaaatgtta tataataaaa ttactaatga tatttaatat tacaagcaat
      121 cttaagaaat tcgaaaagga aaaaatgatt atgaaaaaga aagaaaaaga aagtattgaa
      181 acattgtgtt attctaggaa tattaggaac ttgtctagct ggcattggta caggaataga
      241 cgttgacgca gctacttact atggaaatgg tctttattgt aacaaagaaa aatgttgggt
      301 aaattgggga caatcatggt cagaagggtt aaaacgttgg ggagataatc tttttggtag
      361 ttttagtgga ggacgataat gacttcaata aacattgatc acacaaaaaa agtcatacat
      421 gaattataca atagtttaat gacacgacct aatcagacga aagcattatt agatattact
      481 gatgttttat ttcaggtata taaaaaaatt gatacagcaa aatatcctga aattcttgta
      541 aataaattag ttaattatat ttacatcgtg ggttttgata ataaaatacg ctttattgat
      601 aatgatgaaa aattattaat agaattaggg gatatttcta aaaaagctgg aattaatagt
      661 aaatacaaag caaactttac agataaatcg caattttata gttattcaga aacaatgcct
      721 caacgataaa atatagtata
//
LOCUS       DACBZK010000238          739 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.250, whole genome shotgun sequence.
ACCESSION   DACBZK010000238 DACBZK010000000
VERSION     DACBZK010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.250"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            30..224
                     /locus_tag="IVD66_002983"
     CDS             30..224
                     /locus_tag="IVD66_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147130.1"
                     /translation="MIFAAAAAVASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVIL
                     AAASIVVSLFGLFGQTPQGL"
     gene            294..>739
                     /locus_tag="IVD66_002984"
     CDS             294..>739
                     /locus_tag="IVD66_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147131.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVN"
BASE COUNT          251 a          105 c          172 g          211 t
ORIGIN      
        1 ctgccgcaac tagtttaaaa aacaatctga tgatttttgc tgctgctgcg gccgttgctt
       61 ccattgttat tgggggtctt ttcttcctat ttggacgaag aggagctgaa aatgggaaga
      121 tgcacgtagg ctatgtattg atgggggtag gagttatttt agcagcagct tctattgtgg
      181 tttcgttatt tggattgttt ggacaaacac ctcaaggatt ataagaaagt aaaaaagtag
      241 gagtaagaag tagtcgatac tttttactcc ttttttatga aaggagaata ctcatgtact
      301 ttacgattgc aggcaatacc aaaacagata aagagttaat aaaaaaagca acgaaggaag
      361 taggaaagcg tacttctttt ttaccgaaaa caattaaata ttctgtcatt gaaacggaag
      421 aacagctaca tgtgttaggg aaagtactgg aacacgaaag tcgatcttct gttaagttga
      481 ctctcacgtt acatgacaca gaaggaaaaa tagagaaagc tggtacagaa tacgtttttg
      541 gcccactgga ttatcaaatt tcagaaggtt tctatcctac attgatggat ttgatccgcc
      601 ttgatgtgtt taaagaaacg gatgaaacta tgagtgtgga agagtcttat cgaaacgaaa
      661 aacttttaca agttttagaa gaagagttag agagcgacca aagaaaagtg aatcaaggga
      721 gtgaagtcga agtaaatga
//
LOCUS       DACBZK010000239          738 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.251, whole genome shotgun sequence.
ACCESSION   DACBZK010000239 DACBZK010000000
VERSION     DACBZK010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.251"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            30..224
                     /locus_tag="IVD66_002985"
     CDS             30..224
                     /locus_tag="IVD66_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147132.1"
                     /translation="MIFAAVAAVASIVLGGIFFFFGRRGAENGKMHVGYVLMGVGVIL
                     AAASIVVSLFGMFGQTPQGL"
     gene            293..>738
                     /locus_tag="IVD66_002986"
     CDS             293..>738
                     /locus_tag="IVD66_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147133.1"
                     /translation="MYFTISGNTKKDKELIKKATKKVGKRTAFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVSQVSEVEVN"
BASE COUNT          252 a          108 c          171 g          207 t
ORIGIN      
        1 gtgcagcaac tagtttaaaa aacaatctga tgatttttgc ggctgtagct gccgttgcct
       61 ccattgttct tggggggatt ttcttcttct ttggccgaag aggagctgaa aacgggaaga
      121 tgcacgtagg ttatgtattg atgggggtag gagttatatt agctgccgcc tctattgtgg
      181 tttcgttatt tggaatgttt ggacaaaccc cacagggact ataaaaaata aatagaagga
      241 gtaaaaagta cgtggctact ttttactcct tttttatgaa aggagaatac tcatgtactt
      301 tacgatttca ggcaatacca aaaaagataa agagttaata aaaaaagcaa cgaagaaagt
      361 gggaaagcgt actgcctttt taccgaaaac aattaaatat tctgtcattg aaacggaaga
      421 acagctacat gtgttaggac aagtgttaga acaagagaat caatcttctg ttaaattgac
      481 tctcacgtta catgacacag aaggaaaaat agagaaagct ggtacagaat acgtttttgg
      541 cccactggat tatcaaattt cagaaggttt ttatcctaca ttgatggatt tgatccgcct
      601 tgatgtgttt aaggaaacgg atgaaaccat gagtgtggaa gagtcttatc gaaacgaaaa
      661 acttttacaa gttttagaag aagagttaga gagcgaccaa agaaaagtga gtcaagtgag
      721 tgaagtcgaa gtaaatga
//
LOCUS       DACBZK010000240          735 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.252, whole genome shotgun sequence.
ACCESSION   DACBZK010000240 DACBZK010000000
VERSION     DACBZK010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.252"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(52..240)
                     /locus_tag="IVD66_002987"
                     /pseudo
     CDS             complement(52..240)
                     /locus_tag="IVD66_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            220..>735
                     /locus_tag="IVD66_002988"
     CDS             220..>735
                     /locus_tag="IVD66_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP6147134.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIE"
BASE COUNT          255 a          114 c          163 g          203 t
ORIGIN      
        1 ttttctgaag tacatccgca actgtccata ctctgatgtt ttatatcttt tctaaaagtt
       61 cgctagatag agttctatat tagagatgta aagagttttg gtgaagaggt ttgtgagtat
      121 ggcttttata accagggtgc aatgagaagc actaacagca gctagcttaa gaacgcatag
      181 gatatacttt ttatggaagt cacagaggag gaataaaatt tgaacaggat taacagagta
      241 acctctattc ttattcagct gcaatcaaaa aaaataattc ctgccaaaga aattgcacag
      301 cgatttaata taagcttaag gacagtttac agagatatcc ggacacttga agaagccgga
      361 ataccaattg gatctgaggc cggaaaagga tattttcttg tagagggctt cctacttccg
      421 ccggtaatgt ttacagcggc ggaagtgggt gcattgatta cagcagggaa atttttaaat
      481 tgccatggag atgaatcatt tataaaggat tttgattcag ctatgtataa aatcaaatct
      541 attttgaagc atggtgaaaa aaactatgca caggagttgg agaacagtat taacgtgtac
      601 agcacatctg gacagaaaaa tacattggcg gataacgtta ttgcagcaat tcagactgca
      661 atctgcaata aaagggtaat atcaattcaa tatcctgcat caggagggca agaaccggaa
      721 agcagaatga tagag
//
LOCUS       DACBZK010000241          696 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.253, whole genome shotgun sequence.
ACCESSION   DACBZK010000241 DACBZK010000000
VERSION     DACBZK010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.253"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
BASE COUNT          247 a          116 c           85 g          248 t
ORIGIN      
        1 ccaaattact tcatcaaaac attgatataa tttttattat atcagtattt attcttgata
       61 cataaatgag aaaataaata ctttaaatct attgactaca agtagtcatt aagtcttcat
      121 aagatgtaca atatgacatt aaaaaaataa aagcttacga ccatccgtta aatctgacac
      181 taaataatgg actgctttct tttgtattag caggttacgt tgactatgaa tattcaccag
      241 attatttgga gaaacctctt caacacgaga acaatgatat taattttaga tttgtctacg
      301 agtcaaaaag taaaacatgg ttagttgatc aattaagcac gataaacaca agcttccatg
      361 aattacctaa acctgaaaat gaagttgaga tggtcattaa aatcttctaa aaaagaagcg
      421 ttgaagggga aatattcctt tcaacgctct tttttatatg cttagaaaca taaataaatt
      481 gtatactttc tttttagccc ctattacttt tcacgaaaaa tatctttttt tcgacgctag
      541 cgtttctcta cttctaatac tgtacacagt ttttgtatta ttgaaaaatt actcattatt
      601 tagcattaat ccacatcgtt ttatcaatcg accttcatac taaactactt taaagtcatc
      661 ttccttctcg tttttcatta atggaatggc aacagt
//
LOCUS       DACBZK010000242          690 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.254, whole genome shotgun sequence.
ACCESSION   DACBZK010000242 DACBZK010000000
VERSION     DACBZK010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..690
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.254"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..108
                     /locus_tag="IVD66_002989"
     CDS             <1..108
                     /locus_tag="IVD66_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP6147135.1"
                     /translation="VIVPKTGSTHLVTISAVSLLLLVLATFSYAVLRYI"
     gene            135..599
                     /locus_tag="IVD66_002990"
     CDS             135..599
                     /locus_tag="IVD66_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147136.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            596..>690
                     /locus_tag="IVD66_002991"
     CDS             596..>690
                     /locus_tag="IVD66_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147137.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILER"
BASE COUNT          263 a           90 c          136 g          201 t
ORIGIN      
        1 gtcattgttc ctaaaacagg ttctacacat ttagtaacga tttcagcggt cagcttacta
       61 ttacttgtgt tagcaacttt tagttatgcg gttctgagat acatttaaaa taaaaaaacg
      121 aaagaatgaa taaaatgaaa aagttaataa tagtagttac ttccttgatt gccatgattg
      181 ttattttagt cggatgtagt aatgaaaaaa ataaacaaac taatcaagat aatggcgtat
      241 tgaaatcagg aactatgtgg aaagaagaag taggtggtct tgtttataat ttgaaaatta
      301 tagacgagac tacctgggaa tactctgaga gtgtatggca tccagatcct gtacaaataa
      361 cagtcaagag gcaaaaagac tataaaggtt tagaaagata caaaatagta gattcagctg
      421 gtgttaggga atttataaac aaatctgatt ctttatttat tgttgttccc tatgagaaga
      481 atggcgtaaa aaaaataatt tttcttggat ctagcaagga tgaaaagcga acgaaagaga
      541 aattgattca cgatggatca caatccaata aatataagtt acaaaagact agcgagtgat
      601 tgctagtctt tttatttgtc ctgaaggagg aatcacagtg gcaaaagcta aaacgccatt
      661 tgaaaaagcc gcgtctaaaa tcttagaacg
//
LOCUS       DACBZK010000243          670 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.255, whole genome shotgun sequence.
ACCESSION   DACBZK010000243 DACBZK010000000
VERSION     DACBZK010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.255"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..>670)
                     /locus_tag="IVD66_002992"
     rRNA            complement(<1..>670)
                     /locus_tag="IVD66_002992"
                     /product="16S ribosomal RNA"
BASE COUNT          134 a          213 c          147 g          176 t
ORIGIN      
        1 gtttcaacct tgcggtcgta ctccccaggc ggagtgctta atgcgttagc tgcagcactg
       61 aagggcggaa accctccaac acttagcact catcgtttac ggcgtggact accagggtat
      121 ctaatcctgt ttgctcccca cgctttcgag cctcagcgtc agttacagac cagagagccg
      181 ccttcgccac tggtgttcct ccatatatct acgcatttca ccgctacaca tggaattcca
      241 ctctcctctt ctgcactcaa gtctcccagt ttccaatgac cctccccggt tgagccgggg
      301 gctttcacat cagacttaag aaaccgcctg cgctcgcttt acgcccaata aatccggaca
      361 acgcttgcca cctacgtatt accgcggctg ctggcacgta gttagccgtg gctttctggt
      421 tagataccgt caagggatga acagttactc tcatccttgt tcttctctaa caacagagtt
      481 ttacgatccg aaaaccttct tcactcacgc ggcgttgctc ggtcagactt tcgtccattg
      541 ccgaagattc cctactgctg cctcccgtag gagtttgggc cgtgtctcag tcccaatgtg
      601 gccgatcacc ctctcaggtc ggctatgcat cgtggccttg gtgagccgtt acctcaccaa
      661 ctagctaatg
//
LOCUS       DACBZK010000244          661 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.256, whole genome shotgun sequence.
ACCESSION   DACBZK010000244 DACBZK010000000
VERSION     DACBZK010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.256"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..362
                     /locus_tag="IVD66_002993"
     CDS             <1..362
                     /locus_tag="IVD66_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147138.1"
                     /translation="PEIQPAEVKQEHKNTVETAENKNIVPVGSLWIDKKDGKVMEEDT
                     GRTLHLKDAAFIEDPQHNQVILKGKSYGKEIQTALPSEEFALGNPFRFSLETVSEVAK
                     RKNEIYYEQQLSQKERV"
     gene            423..>661
                     /locus_tag="IVD66_002994"
     CDS             423..>661
                     /locus_tag="IVD66_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147139.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDS"
BASE COUNT          255 a           96 c          142 g          168 t
ORIGIN      
        1 aaccagagat ccaaccagca gaagtgaagc aggagcataa aaatactgta gaaacggcag
       61 agaataagaa tattgtgccc gttggttcac tttggatcga caagaaagac gggaaagtaa
      121 tggaagaaga tacgggtcga acgttacatt tgaaggatgc ggcgtttatt gaagatccgc
      181 agcataatca agtgatttta aaaggaaaaa gttatggaaa agagattcaa acggcgttac
      241 cttcagaaga atttgcgcta ggaaatccat tccgattttc acttgaaaca gtgtcagaag
      301 tggccaaacg aaaaaatgaa atctattatg aacaacaatt gtcacaaaaa gaacgcgtat
      361 aaaacaagta aaaaagacta tctgaaaaac ggatagtctt ttttcttttg ggaggtttga
      421 aaatgaccga aaaaaaaatg agtcttattg atcgatgtaa acagatcgat atagtggatt
      481 ttgctcgaaa caatggaatg gctgtagtca ataaaggacg agactatcgc ttagaagacc
      541 atgattcatt tgtttttgat cgaagaaaac aacgttttta ttggaacagt caaaatatta
      601 gtggcgacat tattgaatta gctaaacttt ttttcataga caaagagatc caagactcta
      661 a
//
LOCUS       DACBZK010000245          659 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.257, whole genome shotgun sequence.
ACCESSION   DACBZK010000245 DACBZK010000000
VERSION     DACBZK010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..659
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.257"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            220..399
                     /locus_tag="IVD66_002995"
     CDS             220..399
                     /locus_tag="IVD66_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147140.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFNIPALKK"
BASE COUNT          256 a           93 c          118 g          192 t
ORIGIN      
        1 tatatgaaaa agattattcc cttattatta gtactatttg ttggcgaaat gcttatgcgt
       61 catgctgcaa ctgtgcattt aaacttcgta gtatttttgg taatactggt gttttgtttg
      121 accttttggc ggtttgtatt agccctcgtg agtttactat tcaagatgat tgcagccata
      181 tttttcatag gattatttcg atgagaggag agagtatcaa tgccaattgc aataggaaat
      241 aaacggttac ccgttacgtt ggatgaaaag agacaaaaag aattacagca acttaaacag
      301 aaatacggta aaagtgaatc caggattatg tgcattgcgt tagatttatt gattgcgcag
      361 gaaaaagcag gattcaacat accagcgctc aaaaagtgac gtcacttttt gacttaaaaa
      421 ataaaagtga tagcactttt atatagtaaa aagaagaata aacgttaagg gatagaaaaa
      481 gagaaaagaa caaaaaaaga gctaacagta ccattgttag ctcttatgca gtaatgaaaa
      541 ccaagccttt aaaaaaggag atgtttcatc acaaacacaa acagaaaaat aaaaaaatca
      601 aaaatctaat aatcataaat tgctaccgaa gcacctttta ttataattaa tcaaatata
//
LOCUS       DACBZK010000246          658 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.258, whole genome shotgun sequence.
ACCESSION   DACBZK010000246 DACBZK010000000
VERSION     DACBZK010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..658
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.258"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(138..491)
                     /gene="tnpB"
                     /locus_tag="IVD66_002996"
     CDS             complement(138..491)
                     /gene="tnpB"
                     /locus_tag="IVD66_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAP6147141.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
BASE COUNT          198 a          144 c          111 g          205 t
ORIGIN      
        1 ttgaagcaac tgaagcaacg tatctgtagt ttccaaaatt tttcaccacc ttgaatcgaa
       61 ctgattttgt tacagaatac cacaagaaac gcacaagaaa taggggttca acacattttt
      121 tgtgttaacc ccccagctta aaaaactcct ttttttcctg gcaaaatagc tcgaggttga
      181 tcgatactta atccttctaa caaccatcga acctgttggt tcgttaaggt tcgaacttcg
      241 tctttcgtcc gaggccattt taacttgccg ttttctatcc gcttataaca gagaagaaaa
      301 ccatcaccgt cccaatagag aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa
      361 acggcatctt cgtaaagctc gagttgatac tcttgttgaa taagactggc aagaccatca
      421 attccttttc gcaaatctgt ttttccgcac acaatataaa tatgtttggt ttgaagtaaa
      481 tcataaagca ttggacaaca gttctttcaa aatagcttga agaatataat tgttaatacc
      541 gttatagatc aaaacttcag aaccattctc tcttttgatg cgcatcgcta acttggcagc
      601 cgcgggttta cctttttctg gtgcactctt ttcgtttcct aattggacag gaacaatc
//
LOCUS       DACBZK010000247          625 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.259, whole genome shotgun sequence.
ACCESSION   DACBZK010000247 DACBZK010000000
VERSION     DACBZK010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.259"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            1..625
                     /locus_tag="IVD66_002997"
                     /pseudo
     CDS             1..625
                     /locus_tag="IVD66_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
BASE COUNT          214 a          110 c          118 g          183 t
ORIGIN      
        1 atgactaaag tgctgactga agaagtaaat gcatttaaag ttagaactct aaatgataag
       61 tatgtcgcta ttttcatgga tgctacttat attcctttaa aacggcaaac cgtctccaaa
      121 gaagcaatct atattgccat tggtatacga gaagacggca ctaaagaagt actaagttat
      181 gcgattgctc cgactgaatc gacctacgtt tggaatgagt tgttacagga catttactcc
      241 agaggggttc atgatgtctt actgtttatt accgatggct taaaaggcat gaaagatacg
      301 attcaccaga tttatcctaa agctaaatac caacattgct gtgttcacgt ttcccgtaat
      361 attgctcata aagtacgtgt caaagatcga aaagaaatct gtgatgattt taaggctgtt
      421 tatcaagcta gctcaaagga agaggcaaat acctttttag ggagtatgat tgagaagtag
      481 caaaaaactt atcctaaagt gacgcagtca ctgataaaaa atcaagattt attgactttt
      541 tatgagtttc cgcctggtat ccgccgaagc atttactcaa ctaatttaat cgaatctttc
      601 aagaaacaaa tcaagaaata cagcc
//
LOCUS       DACBZK010000248          625 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.260, whole genome shotgun sequence.
ACCESSION   DACBZK010000248 DACBZK010000000
VERSION     DACBZK010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.260"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>625
                     /locus_tag="IVD66_002998"
     CDS             <1..>625
                     /locus_tag="IVD66_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP6147142.1"
                     /translation="MTKSFTEEVTSFKERELHDRYAAIYMDATYIPLKRKTVAKEAIH
                     IAVGIRPDGSKEVLSYAIAPTESITIWEEILIDLQERGVKNVLLFITDGLKGMAGAVQ
                     RFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMVYQASSKKAALEARGAFAEKW
                     KTSYPKMVESILSNDYLLTFYDFPLAIRKTIYSTNLIESFNKQIKKYS"
BASE COUNT          183 a          134 c          140 g          168 t
ORIGIN      
        1 atgactaaat catttacgga agaagtcact tcatttaagg aacgtgagct tcatgaccgt
       61 tatgccgcta tttatatgga cgcaacctat atccctttaa agcggaaaac cgtcgccaag
      121 gaagccattc atatcgcagt tggcattcgc ccggacggtt caaaggaagt gttgagctat
      181 gcgattgcac caactgaatc tatcacgatt tgggaagaga ttttaataga cctccaggaa
      241 cgtggcgtga aaaacgtcct ccttttcatc acggatggct taaaggggat ggcaggggcc
      301 gtgcagcggt tctaccccaa agcccgtttt caacattgct gtgtgcacgt ttcccgtaat
      361 atcagtcaca aagtgcgtgt cgatgatcgt aaggaagtct gtgatgattt taaaatggtg
      421 tatcaagcgt catctaaaaa ggcggcattg gaagcacgtg gtgcttttgc ggaaaaatgg
      481 aaaaccagtt atccaaaaat ggtggaatcg atcctttcga acgattacct gctcactttc
      541 tatgattttc cattagccat acgcaagact atttactcta cgaacttgat tgaatccttt
      601 aataagcaaa tcaagaaata cagcc
//
LOCUS       DACBZK010000249          623 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.261, whole genome shotgun sequence.
ACCESSION   DACBZK010000249 DACBZK010000000
VERSION     DACBZK010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..623
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.261"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..450
                     /locus_tag="IVD66_002999"
     CDS             <1..450
                     /locus_tag="IVD66_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HAP6147143.1"
                     /translation="PFPGSSLDKSSFSGGQLFGTNPGGEFRPNGFHDGLDFGSVDHPG
                     SEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQEFANSTGNSRVKVGDQVKV
                     GQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLPFLNSSKK"
BASE COUNT          201 a           97 c          155 g          170 t
ORIGIN      
        1 ccattccctg gcagcagttt agataaaagt tccttcagcg gtggtcaatt atttggaacg
       61 aatccaggcg gtgaattccg tccgaacggc ttccatgatg gattagattt tggttcagtt
      121 gatcatccag gaagtgagat tcatgcggtt catggcggaa aagtcgtgta cgttggcaat
      181 cctggtattt caggtttggg cgcgtgtgtg atcgtgatta attacgatgg cttgaatatg
      241 gtgtatcaag aatttgcaaa tagtacagga aattctcgag tgaaagtagg cgatcaagtg
      301 aaagttggtc aagtaattgg gatacgagat acagcacact tgcatttagg atttactcga
      361 atggattggc gtcaagcaca aggacatgca ttcattgatg atggtacatg gatcgatccg
      421 ttaccatttt tgaatagcag taaaaaatag atcaggagaa aaaatatgga aaataaaacg
      481 ttaaaaatcg tcttaacagc tgcaattagc gttagtttaa tcggcaatat tgcgttgttt
      541 tggcagctga aagaggaaca agcagcaaat acctataaaa ttgaagaagt ggctaaaaac
      601 gcgtctgaga agctcaaaaa aaa
//
LOCUS       DACBZK010000250          623 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.262, whole genome shotgun sequence.
ACCESSION   DACBZK010000250 DACBZK010000000
VERSION     DACBZK010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..623
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.262"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(105..314)
                     /locus_tag="IVD66_003000"
     CDS             complement(105..314)
                     /locus_tag="IVD66_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147144.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            complement(381..620)
                     /locus_tag="IVD66_003001"
     CDS             complement(381..620)
                     /locus_tag="IVD66_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147145.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
BASE COUNT          167 a          136 c           74 g          246 t
ORIGIN      
        1 gacgattaaa gtgactccta aaaaaccaaa taaccatttt ttcatccatc tgcctccttt
       61 cagacaaaac aaaaaaactt tttctcattt ccatagaaaa agttttaaaa atgaattcta
      121 taagttcgtc tcaactgttc aaagtttttc attgaaccta acaaacaagc tttctctttt
      181 cctgttaact gcatatcatt gatatattgc gcgacagata atcttttaag gtgtttttgc
      241 ttcatcgttt ttagtaactt ttcttccatt tctttcgaca ctttttttct gttttcgatt
      301 tcttcataat tcatgagttt tcctaccttc cttgtttttt gcaaaaataa aaaagcctat
      361 gatcacatac gctctacact tcagtcttgg gttatctttt tctttcgttt aattactggc
      421 cgtgctggtt tcaaatcctt gattccatta tgggttctcc aataatcgaa ttcttttcgc
      481 aatctttctt tttccatatc tgttccttta gataaggctt tgaatacttc tttaggtgaa
      541 taaccacgag ctaacagctg tacatacctt ccttttgtca aagtatccat atccatcgcc
      601 tctaaaactg gtcgcgccat cta
//
LOCUS       DACBZK010000251          596 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.263, whole genome shotgun sequence.
ACCESSION   DACBZK010000251 DACBZK010000000
VERSION     DACBZK010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..596
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.263"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..591
                     /locus_tag="IVD66_003002"
     CDS             <1..591
                     /locus_tag="IVD66_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147146.1"
                     /translation="QKEKEREQLEIRKREQDLAEQKMAIEKQRLEQEKEKEAAARKER
                     QEQMDTLRQAQLNYLAQPQPTPSVAAVQTPMNNQTNLTPSPQRSFNGWMVGCIASLSL
                     LLGGGTVFAFNHINQSSQADSVATTTSIKEEAQEQARKEYEQQLEELLNRTNQSTTES
                     SMENSKESDPSKAKEGSSDSTVQSNTSESSESNEVK"
BASE COUNT          242 a          112 c          122 g          120 t
ORIGIN      
        1 caaaaagaaa aagagcgtga acaattagaa ataagaaaac gggaacagga tcttgcggaa
       61 caaaaaatgg cgatagaaaa acaacggtta gagcaagaaa aggaaaaaga agcagctgct
      121 cgtaaggaac gtcaagaaca aatggataca ttgcgacaag ctcagttaaa ttatctagca
      181 caacctcaac caacgccttc agtagctgct gttcaaaccc caatgaacaa ccaaacaaat
      241 ctaactcctt caccacagcg ttcctttaac ggatggatgg tgggatgtat tgcaagttta
      301 agcttgcttc taggtggagg aacagtattt gcttttaatc atatcaatca atcttcacag
      361 gctgattctg tggccacaac gacgtcaatc aaggaagaag cccaagaaca agcaagaaaa
      421 gagtatgaac aacaattaga agaattattg aatcgtacca atcagtcaac aacagaatca
      481 agtatggaaa atagcaaaga gagtgatcct agtaaggcta aagaaggatc aagcgattca
      541 actgtacaat caaacacttc cgaaagttca gaatcaaatg aggtgaaata atgcgt
//
LOCUS       DACBZK010000252          591 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.264, whole genome shotgun sequence.
ACCESSION   DACBZK010000252 DACBZK010000000
VERSION     DACBZK010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.264"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(316..579)
                     /locus_tag="IVD66_003003"
     CDS             complement(316..579)
                     /locus_tag="IVD66_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="circular bacteriocin, circularin A/uberolysin
                     family"
                     /protein_id="HAP6147147.1"
                     /translation="MKKNLLLVLPILGFAGFFVGVPMLSANIGISSYAAKKVIDIINT
                     GSTVATIISIVAAVVGGGLITAGIVATAKSLIKKYGAKYAAAW"
BASE COUNT          224 a          103 c           78 g          186 t
ORIGIN      
        1 cttccttttt tgtatggatt ttttcattta cacaaaatat tttatactct cctgaatttt
       61 ttcatgttga aaacatcact aatcaaaggc aaattataat ttagaaatag aatgaaaaca
      121 ctaaatgaaa atagaacatt agaaaaaata gaatcaaaaa aacccaagac tagtgccgaa
      181 ataagggaaa caatcgaagc tacaaaaaat aatgatttcg ttgaacagga ccaatttatt
      241 tgtttccgat atttctcaaa aagaactttc tttgggaaag ttaaaggcga ctgtaaagtc
      301 gcctttagtc cttttttacc aagctgctgc atatttagct ccatattttt taattaatga
      361 tttggctgta gcaacaatac cagctgtaat taatccgcct ccaacaactg cagcaacaat
      421 agaaatgatt gtagcaaccg tgctaccagt attaattatg tcaataactt ttttagctgc
      481 ataagaagaa attccaatgt tagcacttag cattggtaca ccaacaaaga atcccgcaaa
      541 acctaaaatt ggtaaaacta ataataaatt ctttttcata ataattcctc t
//
LOCUS       DACBZK010000253          587 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.265, whole genome shotgun sequence.
ACCESSION   DACBZK010000253 DACBZK010000000
VERSION     DACBZK010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.265"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
BASE COUNT          191 a           83 c           83 g          230 t
ORIGIN      
        1 aattatagag ccattttttc ttgatgtgat atccttgtct tttttgtaat gtttttaact
       61 tattgctttt gcaaaattta tttacctgtt ttctggatca acgatagtgt acattatgct
      121 atccttgttt ggattttagg acgtttaaag aggcactttt ttacataact taatccatag
      181 accttttaag catgctgtga gataataata aagaagagtt taaagcgcac cccaaaccac
      241 ttccccataa gtgtattacg ctttaaactc ttttatattt gaattcacta agaagcatac
      301 catatttttg aaaaaaagtg agaaaaaagg cttataatta ggatttagag taattaatta
      361 gatgtttatt ttataggact gatactatag attacaaata gtatcgtatt tcgcaatctt
      421 aaaattatct tcttactgtg aataagataa taaaatttgt atttgtcctt tttaggtaac
      481 ttattttaat ctatatacct ttctggatca acgaaagtat actttatata gtcataacgc
      541 cgatggtaac tatgcactgt aacgataatg ctgctaaaat atctttt
//
LOCUS       DACBZK010000254          587 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.266, whole genome shotgun sequence.
ACCESSION   DACBZK010000254 DACBZK010000000
VERSION     DACBZK010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.266"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..582
                     /locus_tag="IVD66_003004"
     CDS             <1..582
                     /locus_tag="IVD66_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147148.1"
                     /translation="QEEKEREQLELKKREQHLAEQKVAIEKQRLEQEKEKEAAARKER
                     QEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQANLTPSPQRSFNGWMVGCIASLSLLLG
                     GGTVFAFNHINQSSQADSVATTASIKEEAQEQARKEYEQQLEELLNRTNQSTAESSME
                     NSKESDPSKAKEGSSDSTVHSNTSESSESNEVK"
BASE COUNT          232 a          111 c          127 g          117 t
ORIGIN      
        1 caagaagaaa aagagcgcga acaattagaa ctaaaaaaac gtgagcagca tcttgcagaa
       61 caaaaagtgg cgatagaaaa acaacggtta gagcaagaaa aggaaaaaga agcagctgct
      121 cgtaaggaac gtcaagaaca aatggataca ttgcgacaag cacagttgaa ttatctagca
      181 caacctcaac cagtagctgc tgttcaaacc ccagtgaaca accaagcaaa tttaactcct
      241 tcaccacagc gttcctttaa cggatggatg gtgggatgta ttgcaagttt aagcttgctt
      301 ctaggtggag gaacagtatt tgcttttaat catatcaatc aatcttcaca ggcagattct
      361 gtagccacaa cggcgtcaat caaggaagaa gcccaggaac aagcaagaaa agagtatgaa
      421 caacaattgg aagaattatt gaatcgtacc aatcagtcaa cagcagagtc aagtatggaa
      481 aatagcaaag agagtgatcc tagtaaggct aaagaaggat caagcgattc aactgtacac
      541 tcaaacactt ccgaaagttc agaatcaaat gaggtgaaat aatgcgt
//
LOCUS       DACBZK010000255          586 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.267, whole genome shotgun sequence.
ACCESSION   DACBZK010000255 DACBZK010000000
VERSION     DACBZK010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.267"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            70..333
                     /locus_tag="IVD66_003005"
     CDS             70..333
                     /locus_tag="IVD66_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP6147149.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            333..>586
                     /locus_tag="IVD66_003006"
     CDS             333..>586
                     /locus_tag="IVD66_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAP6147150.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSART"
BASE COUNT          221 a           72 c          126 g          167 t
ORIGIN      
        1 aaaacaatcg aatttacgta cttaattaag tacgttagaa tggagatata aattagaggg
       61 ggagtagata tggcaaaaac agtcttaaat cctagctcag cacggaaaaa tttttataag
      121 ttgttgaaag atgtaaatga gaatcatacg gaaattgaaa tcattagtga gcgcagtgaa
      181 aataatgcgg tgcttattgg tttggatgat tggaaagcaa tcaaagaaac gctattactt
      241 gagcaaatag gcactttggg tgttgttcgt aagcgagaaa aagatgatag tggatttact
      301 aatgttgatg aaattgattg ggataactta taatgaataa ctattctgtg atgattaaaa
      361 actcggctaa agctgattta aagaaaatca aacagtctaa tttgaaacct caatttgaga
      421 aggttattca gactttaaag gaagatccct atctccctac ccaatcattt gagaagttaa
      481 aacctacaca tgaaggtagg tattctagaa gattgaatag acaacaccgg gttgtttata
      541 aggtagatga agatgaacac gtggttgaaa tttattcagc aaggac
//
LOCUS       DACBZK010000256          581 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.268, whole genome shotgun sequence.
ACCESSION   DACBZK010000256 DACBZK010000000
VERSION     DACBZK010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.268"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>581
                     /locus_tag="IVD66_003007"
     CDS             <1..>581
                     /locus_tag="IVD66_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP6147151.1"
                     /translation="VLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPW
                     NLLDNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATY
                     EDGSPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRQDAVLSEFKSF
                     YNNLNVVGGHPGGSSKLTQADNDFNNLHDKLGDP"
BASE COUNT          210 a          106 c          112 g          153 t
ORIGIN      
        1 gttttagaag gcgtaacaac caacaccaaa gtcaatattg actatggaaa aatcggtacg
       61 tataacggga aaaaagtcaa tatcaagcta gttctatcta atattcactt atactcggat
      121 acgttgccgt ggaatctact agataacaac tatacaaaaa ctcattttcg agacgatggc
      181 tataaaaata cgaatggtgc aatgagtaaa tctaaaaaaa gaacagtact ttggatctca
      241 gacaatcttt tctcaggaat tgtttaccat tcaacacaaa tgaatgtgca gctagtagcc
      301 acatatgagg acggtagccc cgttcaattt tcaggagata catttatcag ttttaactct
      361 ttgaaccctg caggaggaaa aagcacggat cttaaaggag aatatgccca ctatgacaaa
      421 atgaatacga cagattggta tgtcagacaa gatgcggttc tttcagaatt taaatctttc
      481 tacaacaatc tgaacgtggt aggtggccac ccaggaggaa gctctaagct gacacaagcg
      541 gataatgatt tcaataattt gcatgataaa ttaggagatc c
//
LOCUS       DACBZK010000257          560 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.269, whole genome shotgun sequence.
ACCESSION   DACBZK010000257 DACBZK010000000
VERSION     DACBZK010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..560
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.269"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>560
                     /locus_tag="IVD66_003008"
     CDS             <1..>560
                     /locus_tag="IVD66_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147152.1"
                     /translation="DHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEA
                     GYYKFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELAKLCEQVPEKEQKQTVKNEPV
                     SKEQMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMS
                     RFPERSFRNQLLIEEQFPGATACLGRA"
BASE COUNT          215 a           93 c          121 g          131 t
ORIGIN      
        1 gatcatttct atcgagtaga attcaacgaa aatgatccag aaaaaggatt gaaaagttat
       61 ggtggggaga tcgtaacatt agaattgatc gatcaactta aaacgttgga taaccaatac
      121 gctgcagaag caggttatta taaattctat tttgaagaag tgaagaacgg agaagtagta
      181 gatcagatcc gaatggatct aggggatggc gtcaacagta atcaccccat ctatttagag
      241 ttagcaaaat tgtgcgaaca agtacctgaa aaggaacaaa aacaaacggt caaaaatgaa
      301 cctgtttcga aagaacaaat gcagtcgaaa gaaacaaaaa caaaacaaaa gggctatcaa
      361 aaacgaacgg cagaagagat taagcaagaa gtcaaatccc tttcgcaaca ggcactggat
      421 gcggtgaaaa agcataccca ttctcctgaa gacgtgaaag aacttttgaa ttttatgtct
      481 cgttttccag aacgatcctt tagaaatcaa ttattgattg aggaacaatt tccaggtgca
      541 acggcttgtt taggtcgtgc
//
LOCUS       DACBZK010000258          528 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.270, whole genome shotgun sequence.
ACCESSION   DACBZK010000258 DACBZK010000000
VERSION     DACBZK010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.270"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(5..90)
                     /locus_tag="IVD66_003009"
     tRNA            complement(5..90)
                     /locus_tag="IVD66_003009"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="IVD66_003010"
     tRNA            complement(107..178)
                     /locus_tag="IVD66_003010"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="IVD66_003011"
     tRNA            complement(190..262)
                     /locus_tag="IVD66_003011"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="IVD66_003012"
     tRNA            complement(280..361)
                     /locus_tag="IVD66_003012"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="IVD66_003013"
     tRNA            complement(369..441)
                     /locus_tag="IVD66_003013"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="IVD66_003014"
     tRNA            complement(445..517)
                     /locus_tag="IVD66_003014"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DACBZK010000259          517 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.271, whole genome shotgun sequence.
ACCESSION   DACBZK010000259 DACBZK010000000
VERSION     DACBZK010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.271"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            57..>517
                     /locus_tag="IVD66_003015"
     CDS             57..>517
                     /locus_tag="IVD66_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6147153.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYS"
BASE COUNT          191 a           72 c          105 g          149 t
ORIGIN      
        1 ataaatatgt tataatagta tcaaatgaat attgctaaaa gaaaagaggt aggaacgtgg
       61 tagcgaagaa atatgtaatc ggtaatttta aaggtggcgt aggtaaaagt acgtgcgcgc
      121 aaatgttagg gtttgaatca gcagttaatg aaggaaaaag aaccttgata attgacttgg
      181 atatgcaagg aaatacttct gatgtgatga acttaacgca tatgaacttc actaacgaag
      241 aaggaggcgg agaaggtgaa ccgattgttt acgaaaatac tgtgactgac gtgttgataa
      301 acaatcttcc acctaaagag gctgtctata aagtaatcaa taacctctat atacttccag
      361 cagacatgtc ctttgaaatg tatgatgatt ggatcaaaga ccaatataat gattcattat
      421 cccaattcaa atatatgaaa gaaaagctag aaccattatt tgatgagttt gacgtcatct
      481 atttagatgt cccaccttct atttctgtat atagtaa
//
LOCUS       DACBZK010000260          514 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.272, whole genome shotgun sequence.
ACCESSION   DACBZK010000260 DACBZK010000000
VERSION     DACBZK010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.272"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..132)
                     /locus_tag="IVD66_003016"
     CDS             complement(<1..132)
                     /locus_tag="IVD66_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP6147154.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          186 a           94 c           92 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaa
//
LOCUS       DACBZK010000261          513 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.273, whole genome shotgun sequence.
ACCESSION   DACBZK010000261 DACBZK010000000
VERSION     DACBZK010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.273"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            25..>513
                     /locus_tag="IVD66_003017"
     CDS             25..>513
                     /locus_tag="IVD66_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HAP6147155.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMD"
BASE COUNT          188 a           93 c           85 g          147 t
ORIGIN      
        1 attcacagaa aagaggactt ccctatgaat gattttacta cagaaattgt gcaaactcta
       61 gtcactaaag gcgatttaaa tgaattattc cgttcgcact tagaaaaagc gataaacaca
      121 ctcctacgga ctgaattaac ggctttttta gattacgaaa aatatgatcg cactggtttt
      181 aattcaggta attcgagaaa cggttcttac tttcgatcaa tcaaaaccga atatggtgaa
      241 ttaacattgg aaatacctag agatcgtaat ggtgagttta aacaacaaac tttaccagcc
      301 tacaaaagaa caaacgatac attggaaacc actattatcc atttattcga aaaaggtgtt
      361 acgatgtctg aaattgctga tttgatcgaa aaaatgtacg gtcatcacta tactccacaa
      421 accatgtcca acatgactaa agttctgact gaagaagtaa atgcctttaa atccagagcc
      481 ttaaatgata agtatgtcgc tatttttatg gac
//
LOCUS       DACBZK010000262          504 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.274, whole genome shotgun sequence.
ACCESSION   DACBZK010000262 DACBZK010000000
VERSION     DACBZK010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.274"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..354
                     /locus_tag="IVD66_003018"
     CDS             <1..354
                     /locus_tag="IVD66_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP6147156.1"
                     /translation="TQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVD
                     QEMYKQAQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISI
                     LKELEEHENWYAEVE"
BASE COUNT          201 a           70 c          111 g          122 t
ORIGIN      
        1 acccaagtaa aatcgatgag aaatgcgatg caatatcttg agtatatgga cttttttgtg
       61 aaagaatttg atacaaattt atatgttgct ggtgttattc ctttcatgtt ggaaagcggt
      121 gacgcagtag atcaggaaat gtataaacaa gcccaagaga tttatgggga acatttgatt
      181 aaaaatgttg tactcaaaaa tgcgcgctta aaacgatacg acggatcagg tattacgatg
      241 gagaagacaa agaaaggtct cttaaaacaa tgggatcgca aaagccacga attatttatc
      301 agtattttga aagaattgga agaacacgag aattggtatg cggaggtgga gtaattggct
      361 gacatcaaag gacttgatat ttttgggaac aacaaaggac tcgccaaaat aaaaaaagaa
      421 gcagaagcaa agaaaaagca gcaagcaatt acaccatctg aaaataagca attagaagtg
      481 caccaagttc aagaaataaa aact
//
LOCUS       DACBZK010000263          504 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.275, whole genome shotgun sequence.
ACCESSION   DACBZK010000263 DACBZK010000000
VERSION     DACBZK010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.275"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
BASE COUNT          226 a           70 c           81 g          127 t
ORIGIN      
        1 ccttaggcag cttttgctgt gtagaaagga ataaataata acgaaagttc aaaagctaat
       61 gccgactatt ctagacatta aagaagacga aaacgaacga taaagaaaga aaagttatga
      121 ataatcgttt attgaaaaaa acttgaaaaa atacaaaaaa ttcgttgacc aagctaaatt
      181 tagttggtat attattactt gtccaaaaga cagaagaaaa tatttattca aaaacataac
      241 aaaaaagtta ttgacatgtt actaacgaca tgataagata actgagtcgt taaaaaagaa
      301 ccacttgcga agcttgattc tatcgaaaaa aacttcaaaa aagttcttga caaataacaa
      361 acgataagtt atgataaatg agttgccgaa agatttcgaa aaacgaaatc gaaaaaaact
      421 tttaaaaaag agttgacaat cgcttgtctc tctgatatga tataaaagtt gctacggcag
      481 ccaaaaatga atcgggaaac actc
//
LOCUS       DACBZK010000264          496 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.276, whole genome shotgun sequence.
ACCESSION   DACBZK010000264 DACBZK010000000
VERSION     DACBZK010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.276"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>496
                     /locus_tag="IVD66_003019"
     CDS             <1..>496
                     /locus_tag="IVD66_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147157.1"
                     /translation="GYHKVTFTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGY
                     TDAKWPEEATQPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIK
                     NKEDLPKDTKYTWKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYE
                     PTVEG"
BASE COUNT          200 a           79 c          115 g          102 t
ORIGIN      
        1 caggctacca caaagtaacc ttcaccgcag gagaaggaac aagtattgaa agtggaacaa
       61 cagtctttgc agtgaaagac ggcgtaagct taccagaaga taaacttcca gtgttgaaag
      121 caaaagatgg ttatacagat gcgaaatggc cagaggaagc aactcaacca attacagcag
      181 atgatacaga atttgtatca agtgcaacaa aactggatga taaatctgac gctgacaaat
      241 ataatcctga aggtcaaaaa gtgactacag aattgaataa ggaaccagac gcatttgagg
      301 gaattaagaa caaagaagat ttaccaaaag atactaagta tacttggaaa gaaaaagtag
      361 atgttagcgc agctggaaat aaaaaaggga ctgttgtagt gacatatcca gatggatcat
      421 ctgatgaagt tgaagtagat gttacagtga cagacaatcg ttctgacgcc gataaatatg
      481 agccaacagt agaagg
//
LOCUS       DACBZK010000265          493 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.277, whole genome shotgun sequence.
ACCESSION   DACBZK010000265 DACBZK010000000
VERSION     DACBZK010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.277"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
BASE COUNT          183 a           73 c           87 g          150 t
ORIGIN      
        1 tctatatttt gatatacaaa ttacagcttc agatactaag ttgcataaac cttttccgga
       61 ccccatacaa aaggcaattg atgaattggg cataaaaaat aagaaacgat ttatattggt
      121 gattcattat atgacatgca aagtgcgaaa gcttgtggga tagcatttgg tttagctaaa
      181 tggggagcca aaaatataga aaattttcaa agtgtagata taattattga ttctcctcaa
      241 gaaatacttg atttgttaga aaaatagaca aagagcgtga gataaggata gggtctcacg
      301 ctctttgttt ttcgccattt aaagattgaa atttttgcca tcgccgattg taaaattaag
      361 ctagacaact aaaaaagtca tttgtgctac actcaaaata gttccgacca aagaattata
      421 aggagtgagt acaaatgacc tatacccatc ttacaacgga tgaacttgta ataatagagt
      481 cttatttcaa aat
//
LOCUS       DACBZK010000266          491 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.278, whole genome shotgun sequence.
ACCESSION   DACBZK010000266 DACBZK010000000
VERSION     DACBZK010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.278"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..447
                     /locus_tag="IVD66_003020"
     CDS             <1..447
                     /locus_tag="IVD66_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147158.1"
                     /translation="AVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVHEDKV
                     KDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLPYQVA
                     DDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
BASE COUNT          222 a           74 c           96 g           99 t
ORIGIN      
        1 gcagtgaagc taacgcatgt accagaagaa tatatcgcca tgcgtttaac cattattcct
       61 gaaaaaattg atccaaaagt ggatatgcaa gaaccacaag atctgattta ttacgtgcac
      121 gaagataagg ttaaagatca agtgaaagat gaagattatg aacaacacgc gatcaattac
      181 aaagtgaaag gatacaagaa agaacaaaaa gcagctcaaa aacaaatgga atctttccaa
      241 gcaaccattg atttgaatga agaattagtg aagaagctaa aagatcaatt gccttatcaa
      301 gtcgcagatg atcaggaaaa tactgaaaac aagattaata gctaccagca agaaattgaa
      361 acatcgaaaa cgcaactgaa agatcaagaa gagatcattc aaaaacttca agaaaaaatt
      421 gatcgtatga caaaagaaaa gatttagaag gacaggtgga gtgaaaaaat gaagcgaaca
      481 aacttggctg a
//
LOCUS       DACBZK010000267          487 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.279, whole genome shotgun sequence.
ACCESSION   DACBZK010000267 DACBZK010000000
VERSION     DACBZK010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.279"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..>487)
                     /locus_tag="IVD66_003021"
     CDS             complement(<1..>487)
                     /locus_tag="IVD66_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HAP6147159.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IK"
BASE COUNT          142 a           92 c           86 g          167 t
ORIGIN      
        1 gttttatccg ttcattattg tagtaataga tatagctatc gatggctgat tttaattcct
       61 cgaaacagtt ataaactttc ccgtgaaaaa tctcttgttt taataagcca aaaaaattct
      121 ccataagtga attatctaag cagttccctt tccgagacat gctttgaaag attttgtact
      181 ccttcaattt gtttctataa gctttcattt gatacgccca accttgatct gagtgaaacg
      241 tacgacgata gggacaatcg ttagtggtct ggatagcttc ctccaaacct tccattaccg
      301 ctaatgcatt gggcttttca gagatacgat aggataaaat ctcactattg aacatatcca
      361 taaaaggatc tagatacaat ttcttttgac ggataatgcc tttggcatcc acttcatggt
      421 atttaaattc agttgtatcc gtcgtgattt tctgatggca gatactggtg tagaaacgac
      481 gatggat
//
LOCUS       DACBZK010000268          482 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.280, whole genome shotgun sequence.
ACCESSION   DACBZK010000268 DACBZK010000000
VERSION     DACBZK010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.280"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..408)
                     /locus_tag="IVD66_003022"
     CDS             complement(<1..408)
                     /locus_tag="IVD66_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147160.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKP"
BASE COUNT          179 a           78 c           62 g          163 t
ORIGIN      
        1 cggctttcca aatgatgaaa tacctaaatc taacttatta agaaagttga aatttttata
       61 ttcaggaaac catttattaa tttcatgtgc agcacgtaat gcattccctg gagttgtcaa
      121 agagaaaatt aattctgcta agcttattat tgaaaatact gataacttat aattatatcg
      181 tccattgaca atcaaatata aactaactat acttgttaga acaaaaaaac aggcgttgac
      241 ttgttcttga ttagttaaaa atatcaataa aggaatactt acccaatata tttttctatt
      301 tatttcttct cctcttaaga gttgaaaaaa cggataaaaa gttagtaaac taaatgctac
      361 tggccactga tagttcaagg tggttgctct ccaaccggtt tcccccatta ctgtcaatgg
      421 tattaaacag tatatagagc aaaccaataa taaattttta acatttattt tctcaaaaac
      481 at
//
LOCUS       DACBZK010000269          478 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.281, whole genome shotgun sequence.
ACCESSION   DACBZK010000269 DACBZK010000000
VERSION     DACBZK010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.281"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>478
                     /locus_tag="IVD66_003023"
     rRNA            <1..>478
                     /locus_tag="IVD66_003023"
                     /product="23S ribosomal RNA"
BASE COUNT          140 a           95 c          141 g          102 t
ORIGIN      
        1 cggagccgca gcgaaagcga gtctgaatag ggcgtttgag tatgtagtcg tagacccgaa
       61 accatgtgat ctacccatgt ccaggttgaa ggtgcggtaa aacgcactgg aggaccgaac
      121 ccacgtacgt tgaaaagtgc ggggatgagg tgtgggtagc ggagaaattc caaacgaact
      181 tggagatagc tggttctctc cgaaatagct ttagggctag cctcggaatt gagaatgatg
      241 gaggtagagc actgtttgga ctaggggccc atctcgggtt accgaattca gataaactcc
      301 gaatgccatt cattcatatc cgggagtcag actgtgagtg ataagatcca tagtcgaaag
      361 ggaaacagcc cagaccacca gctaaggtcc caaaatatat gttaagtgga aaaggatgtg
      421 gggttgcaca gacaactagg atgttggctt agaagcagcc accatttaaa gagtgcgt
//
LOCUS       DACBZK010000270          464 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.282, whole genome shotgun sequence.
ACCESSION   DACBZK010000270 DACBZK010000000
VERSION     DACBZK010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.282"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>464
                     /locus_tag="IVD66_003024"
     CDS             <1..>464
                     /locus_tag="IVD66_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147161.1"
                     /translation="SGYRRYISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFY
                     LVIAASTDFETGQRMKSAIEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGF
                     LYVVALIVLTIALFKGSQSVTKIFGVDTSLKNGSNSLLSMFALGNVAKNVGSG"
BASE COUNT          124 a           75 c           99 g          166 t
ORIGIN      
        1 tcaggctatc gccgatacat tagtagtcca ggtattattt tagctggtga atcttctttg
       61 tcggtagcct atttatttat cttgtttacg attgttactt gcattattga gctggtattt
      121 aaaaaattct atttagtgat tgccgcgtca acggactttg agacaggaca acggatgaaa
      181 agtgctatag aagatatttc tcaatccttc ttgttattgg catttacgat tttagaatta
      241 cgaatctata cattaatgct ttcaggtatc ggtgatttgc atgcggcagg aaagatcaat
      301 ggattcttgt atgttgtcgc tttaattgta ttaaccattg cgctattcaa aggctctcaa
      361 tcagttacga aaattttcgg cgttgatacg agtctgaaaa acggcagcaa ttctcttctt
      421 agcatgtttg ccttaggaaa tgttgcgaaa aatgtgggta gcgg
//
LOCUS       DACBZK010000271          464 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.283, whole genome shotgun sequence.
ACCESSION   DACBZK010000271 DACBZK010000000
VERSION     DACBZK010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.283"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>464
                     /locus_tag="IVD66_003025"
     CDS             <1..>464
                     /locus_tag="IVD66_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147162.1"
                     /translation="SGYRRYISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFY
                     LVIAASTDFETGQRMKSAIEDISQSFLLLAFTILELRIYTLMLSGIGDLHAVGKINGF
                     LYVVALIVLTIALFKGSQSVTKIFGVDTSLKNGSNSLLSMFALGNVAKNVGSG"
BASE COUNT          122 a           71 c          104 g          167 t
ORIGIN      
        1 tcaggctatc gtcgatacat tagtagtcca gggattattt tggctgggga atcttctttg
       61 tcggtagcct atttatttat tttgtttaca atcgttactt gcattattga gctagtattt
      121 aaaaaattct atttagtaat tgccgcgtca acggactttg agacaggaca acggatgaaa
      181 agtgcgatag aagatatttc tcaatccttc ttgttattgg cgtttacgat tttagaatta
      241 cgaatctata cattaatgct ttcaggtatc ggtgatttgc atgcggtagg aaagatcaat
      301 ggattcttgt atgttgttgc tttaattgtg ctaactattg cgctattcaa aggctctcaa
      361 tcggttacga agattttcgg tgttgatacg agtctgaaaa acggcagcaa ttctcttctt
      421 agcatgtttg ccttaggaaa tgttgcgaaa aatgtgggta gcgg
//
LOCUS       DACBZK010000272          460 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.284, whole genome shotgun sequence.
ACCESSION   DACBZK010000272 DACBZK010000000
VERSION     DACBZK010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.284"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            2..>460
                     /locus_tag="IVD66_003026"
     rRNA            2..>460
                     /locus_tag="IVD66_003026"
                     /product="23S ribosomal RNA"
BASE COUNT          151 a           93 c          128 g           88 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat
//
LOCUS       DACBZK010000273          460 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.285, whole genome shotgun sequence.
ACCESSION   DACBZK010000273 DACBZK010000000
VERSION     DACBZK010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.285"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(20..91)
                     /locus_tag="IVD66_003027"
     tRNA            complement(20..91)
                     /locus_tag="IVD66_003027"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="IVD66_003028"
     tRNA            complement(113..200)
                     /locus_tag="IVD66_003028"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="IVD66_003029"
     tRNA            complement(225..298)
                     /locus_tag="IVD66_003029"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="IVD66_003030"
     tRNA            complement(312..382)
                     /locus_tag="IVD66_003030"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="IVD66_003031"
     tRNA            complement(384..459)
                     /locus_tag="IVD66_003031"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
BASE COUNT          132 a          128 c          108 g           92 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca
//
LOCUS       DACBZK010000274          449 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.286, whole genome shotgun sequence.
ACCESSION   DACBZK010000274 DACBZK010000000
VERSION     DACBZK010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.286"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..>449)
                     /locus_tag="IVD66_003032"
     CDS             complement(<1..>449)
                     /locus_tag="IVD66_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147163.1"
                     /translation="DKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRISQKIFYSGLAY
                     LPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWNPLTPTTSLGT
                     RLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYP"
BASE COUNT          144 a           82 c           77 g          146 t
ORIGIN      
        1 cggataaatt tgttggattt cctttaacgt ttttaatcgg ttatctcctt tttgcccatc
       61 tgctagcgga cgaaaccaca tgtccatttt caatcccata agtacagctg gaacaacaca
      121 aatcgtagaa acaactaaac gtgtgcctaa acttgttgtt ggggtcaaag gattccaaaa
      181 accagttgaa tcaaaatgga ataactgcgg catttcttgt aactgaaaaa tattcactcc
      241 ttgtaaactt cctggaataa tctcaaatcg atgaaatgct tctggtattc ttgtaacaac
      301 atagtttaaa ggaagataag ctaagccact ataaaaaatc ttttgagaaa tacgtttgtc
      361 atgtttttct ggtagctctt ctcctgaagg agtatagcga tagaaatgag aaagatacct
      421 attcttttct aaattgaatc gtttgtctt
//
LOCUS       DACBZK010000275          430 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.287, whole genome shotgun sequence.
ACCESSION   DACBZK010000275 DACBZK010000000
VERSION     DACBZK010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.287"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>430
                     /locus_tag="IVD66_003033"
     CDS             <1..>430
                     /locus_tag="IVD66_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HAP6147164.1"
                     /translation="LYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPD
                     NYPDFNSEFGHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWF
                     SRFPKNFFKSITFDCGKEFSNWKAISNQHDIDIYFADPGTP"
BASE COUNT          143 a           84 c           73 g          130 t
ORIGIN      
        1 cactttatcg tttattttct aaaggaatat ttgatattga cacactaccg atgaaaggta
       61 aaagaaaacc caatggccat caggaaaaac ggggaaaaca acagtatcag cgctcaatcc
      121 atgatcgacc tgataattat cctgatttca attctgagtt tggtcacctt gaaggtgata
      181 cgatcgttgg cattcatcat aaaagtgccg tcattacttt agttgaaaga ttatctaaag
      241 tcattatcac gattaaaccc aacggccgta aggcattaga tattgaaact gcccttaatc
      301 aatggttttc tcgcttccct aaaaacttct ttaaatctat tacgtttgac tgtggaaaag
      361 aattttctaa ctggaaagcc attagtaacc aacatgatat tgatatatat tttgcggacc
      421 ctggaacacc
//
LOCUS       DACBZK010000276          429 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.288, whole genome shotgun sequence.
ACCESSION   DACBZK010000276 DACBZK010000000
VERSION     DACBZK010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.288"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>429
                     /locus_tag="IVD66_003034"
     CDS             <1..>429
                     /locus_tag="IVD66_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147165.1"
                     /translation="EDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASAV
                     KEGLKDAYGEGQVNAAVKANTTSEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEG
                     QHGQLPKTDPEQYRYKSNINSENEKRISDLPKRNQEVQTD"
BASE COUNT          193 a           74 c           87 g           75 t
ORIGIN      
        1 tgaagatctt acagaaaaag ccaaagacac cttagaagag aaattagacg gcacgagagc
       61 taaagaattg gctgaagctg tgaagaatcc atccgaagca ctagaaaaac aaaaagaaaa
      121 agcttcagca gtcaaagaag gactaaaaga tgcgtatggt gaaggacaag tcaatgcagc
      181 agtgaaggct aatacaacaa gtgaaaaaga aaatcaagaa ggtgcagcga ttccttcagc
      241 caaagatcac caagatgagt tacattctaa cgaaaattcg atcggagaaa aagattcaga
      301 agaaggacaa catggtcagt taccaaaaac cgatccagaa caatatcgtt ataaatctaa
      361 cattaattct gaaaacgaaa aacgcatttc agatttacca aaacgaaatc aagaagtaca
      421 aacggatga
//
LOCUS       DACBZK010000277          420 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.289, whole genome shotgun sequence.
ACCESSION   DACBZK010000277 DACBZK010000000
VERSION     DACBZK010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.289"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            74..403
                     /locus_tag="IVD66_003035"
     CDS             74..403
                     /locus_tag="IVD66_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP6147166.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
BASE COUNT          162 a           49 c           76 g          133 t
ORIGIN      
        1 cttgtaaata cattatctcg tggtataatg tatttactaa gtaattacat actgttagaa
       61 atgagggatt taaatgatta caaaaacaag aaaacaaggc aattcaatca tgttgacagt
      121 acctaaagat tttaatgttc ctaatggagt cgaagttgaa gcaaagttgg tagagaatgg
      181 tattctttat gaatttgttg aaccacaaaa agaattttat gattttagcg aagatatttt
      241 gtctgatata attgcagaag gctacgataa agatgagatt cttgtagaat ttaagaatag
      301 aaaaaacaaa atgcattctt cctttagaga tattgctgaa gatacactta ctaattctaa
      361 agtaatgact aaagaggagt tggcaacaga aattggctta tgaaatcgtt ccttcaaaac
//
LOCUS       DACBZK010000278          415 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.290, whole genome shotgun sequence.
ACCESSION   DACBZK010000278 DACBZK010000000
VERSION     DACBZK010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.290"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..339)
                     /locus_tag="IVD66_003036"
     CDS             complement(<1..339)
                     /locus_tag="IVD66_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6147167.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DACBZK010000279          414 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.291, whole genome shotgun sequence.
ACCESSION   DACBZK010000279 DACBZK010000000
VERSION     DACBZK010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.291"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            51..287
                     /locus_tag="IVD66_003037"
                     /pseudo
     CDS             51..287
                     /locus_tag="IVD66_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          150 a           71 c           61 g          132 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgttattaa
       61 aaaatcttcc tgaaacactt gatgcacaac ttcgcacgaa acttcaaaac cttttaacgt
      121 atgaagaagg tatttacaat gctatgattt acccgtattc taatggcaaa atagaggcca
      181 agattcccca tatcaagaca ctgaaacgat tatcttatgg atttaaatca tttgagaaca
      241 tgaaaatcag gatttttttg atcaatcaat tgattcaagt gaaataacaa aaaaatctga
      301 gacagaaggt cagtccttct atcggctcta tactttttga tgttggtgaa cttcaccaac
      361 atcttttttg tataaaaaaa tatagaaaag acaccctgaa atcctttaga atta
//
LOCUS       DACBZK010000280          411 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.292, whole genome shotgun sequence.
ACCESSION   DACBZK010000280 DACBZK010000000
VERSION     DACBZK010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.292"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>411
                     /locus_tag="IVD66_003038"
     CDS             <1..>411
                     /locus_tag="IVD66_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147168.1"
                     /translation="EDLTEKAKDTLEEKLDGTRAKELAEAVKNPSETLEKQKEKASEI
                     KEGLKDAYGEGQVNAAVKANTTTEKENQEGAAIPSAKDHQDELHSNENSEEGQNGQLP
                     KTDPEQYRYKSNINSENEKRISDLPKRNQEVQTD"
BASE COUNT          191 a           70 c           78 g           72 t
ORIGIN      
        1 tgaagatctt acagaaaaag ccaaagacac cttagaagag aaattagacg gcacgagagc
       61 taaagaattg gctgaagctg tgaagaatcc atccgaaaca ctagaaaaac aaaaagaaaa
      121 agcttcagaa atcaaagaag gactaaaaga tgcgtatggt gaaggacaag tcaatgcagc
      181 agtaaaagct aatacaacaa ccgaaaaaga aaatcaagaa ggtgcagcga ttccttcagc
      241 caaagatcac caagatgagt tgcattctaa cgaaaattca gaagaaggac aaaatggtca
      301 attaccaaaa acagatccag aacaatatcg ttataaatct aacattaatt ctgaaaatga
      361 aaagcgcatt tcagatttac caaaacgaaa tcaagaagta caaacggatg a
//
LOCUS       DACBZK010000281          410 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.293, whole genome shotgun sequence.
ACCESSION   DACBZK010000281 DACBZK010000000
VERSION     DACBZK010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.293"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..>410)
                     /locus_tag="IVD66_003039"
     CDS             complement(<1..>410)
                     /locus_tag="IVD66_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HAP6147169.1"
                     /translation="YGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDL"
BASE COUNT          120 a           73 c           69 g          148 t
ORIGIN      
        1 agatccaagt ccgcatgtgt acaatgtatg tctatatcat tgatatccca cgatggattg
       61 aaatcttcaa tatattgata agcataagga agattcgttt ccccatgatt aaaaatagga
      121 tacggccgta ttttatgacc tttcaaatct tgtcgtttta aaggagcgag tacaatcgtt
      181 tcaccttcta aaaaagtaga aattctttca ggagttaaga tgcgatctga atcaacattg
      241 cgattgatat gagtattcat acctaatgaa ttgatggtac tgttctcttg ttcaaccgtc
      301 ttattcccca cttttttgga aaattcttct atggtattat cgtctgtcga cataatataa
      361 atatgtgtct gacaattttc tttgataatc gctgcgtttt gttccccata
//
LOCUS       DACBZK010000282          405 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.294, whole genome shotgun sequence.
ACCESSION   DACBZK010000282 DACBZK010000000
VERSION     DACBZK010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.294"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..382
                     /locus_tag="IVD66_003040"
     CDS             <1..382
                     /locus_tag="IVD66_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP6147170.1"
                     /translation="KEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSLIEN
                     QDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYN
                     QKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          157 a           72 c           63 g          113 t
ORIGIN      
        1 aaaagaaatc tgtgatgact ttaaggctgt ttatcaagct aactcaaaag aagaagcgaa
       61 taccttctta tccggcatga ttgagaaatg gaagaaaaac tatcctaaag tgacgcagtc
      121 actcatagaa aaccaagact tattaacttt ttatgatttt ccacctagca ttcgtagaac
      181 catttactca accaatctaa tcgagtcttt caataagcaa attaaaagat acagccgtag
      241 aaaagagcag tttcaaaatg aagaatcact agaacgcttt ctagtcagca tttttgatac
      301 atacaatcaa aaatttctaa acagaagcca taaaggtttt caacaggtaa ccgatacatt
      361 agtttcaatg tttactgagt aactaattat tttgcaggag gacaa
//
LOCUS       DACBZK010000283          401 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.295, whole genome shotgun sequence.
ACCESSION   DACBZK010000283 DACBZK010000000
VERSION     DACBZK010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.295"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>401
                     /locus_tag="IVD66_003041"
     CDS             <1..>401
                     /locus_tag="IVD66_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAP6147171.1"
                     /translation="FPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATI
                     DNLSRAERQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVK
                     YWKRGDIDTATQLTNTFTNTIYYDANASDNK"
BASE COUNT          140 a           68 c           81 g          112 t
ORIGIN      
        1 gttttcctgg ttatggcgga ataccaatta ctcattataa aaagtactgg tatattcaga
       61 cggatacagt aaatacttgt attgttggta cttcccgttc agggaaagga cagatagaag
      121 ttttagcaac cattgacaat ttgtctcgtg cagaaagaca aagttcaatg gttgttaatg
      181 atccaaaaac agaattatat gttgctagta aagatgaact agaagctaga gggtatgatg
      241 tgtatgcatt taatatcacc gatccactgc aatcaatgag tgataatcca ttggcactca
      301 tcgtgaaata ctggaagcga ggagacatag acacagcgac acagttaacc aatactttca
      361 cgaatacgat ttattatgat gccaacgctt cagacaataa a
//
LOCUS       DACBZK010000284          400 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.296, whole genome shotgun sequence.
ACCESSION   DACBZK010000284 DACBZK010000000
VERSION     DACBZK010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.296"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
BASE COUNT          141 a           81 c           64 g          114 t
ORIGIN      
        1 ccgttttttc atccattcct ttcttccccc ccttacaaat aaataataac ctttaacaac
       61 caactcgtaa ataggttggt tgttattata caaaaggata ttagtactca gataaaaagt
      121 tgttagtact cagataaaaa gttgttagta ctcagataaa aagttgttag tactcagata
      181 aaaagttgtt agtacccttc tgtatccgtt gggagagtaa ggctcaactg ccccctaaaa
      241 agggttctaa aaaatcttta aaaaataaat aaaataaacg cgcgcgcgcg agcaaaattt
      301 cccgccaaaa aatcacccac tttttaaaat aaacaggttc gcgcatgata ttaaactgcc
      361 aatctagctc cctatggtcg ctgtaagaag gagtgatcgc
//
LOCUS       DACBZK010000285          394 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.297, whole genome shotgun sequence.
ACCESSION   DACBZK010000285 DACBZK010000000
VERSION     DACBZK010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..394
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.297"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..285
                     /locus_tag="IVD66_003042"
     CDS             <1..285
                     /locus_tag="IVD66_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP6147172.1"
                     /translation="EVAEDDPYWEIEASYIAQCAYNTTLMFSPDVIIFGGGVMKQRHM
                     LQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGTLGCLALAREAVLHS"
BASE COUNT          117 a           73 c           92 g          112 t
ORIGIN      
        1 gaggttgcag aagatgatcc ttattgggaa atcgaagcct cctatattgc tcaatgtgcc
       61 tacaatacaa ccttgatgtt ttctccagat gtgatcattt ttggcggtgg tgtgatgaaa
      121 caacgccata tgctgcaaaa cgtccacgac gcatttgcaa aattggtcaa tgggtatgtc
      181 gaaacacctg agttaagcaa atatatcgtg accccagcat tagaagacaa cgctggaacg
      241 ctcggttgtt tggcattggc tcgagaagcg gtcttacatt cataaacgaa aaaaggctct
      301 tcgacattta gtgttggtag agaaagatac aactgaaaat ttagtcataa ccagttaggc
      361 agagtgctta actggttttt gttttacttg gaag
//
LOCUS       DACBZK010000286          381 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.298, whole genome shotgun sequence.
ACCESSION   DACBZK010000286 DACBZK010000000
VERSION     DACBZK010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.298"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(21..94)
                     /locus_tag="IVD66_003043"
     tRNA            complement(21..94)
                     /locus_tag="IVD66_003043"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58..60),aa:Ile,seq:cat)
     gene            complement(108..181)
                     /locus_tag="IVD66_003044"
     tRNA            complement(108..181)
                     /locus_tag="IVD66_003044"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(145..147),aa:Met,seq:cat)
     gene            complement(209..281)
                     /locus_tag="IVD66_003045"
     tRNA            complement(209..281)
                     /locus_tag="IVD66_003045"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:Ala,seq:tgc)
     gene            complement(301..374)
                     /locus_tag="IVD66_003046"
     tRNA            complement(301..374)
                     /locus_tag="IVD66_003046"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(338..340),aa:Pro,seq:tgg)
BASE COUNT          103 a          108 c           90 g           80 t
ORIGIN      
        1 tgaaacttac aacgccacaa tggaccttgt aggactcgaa cctacgaccg gacggttatg
       61 agccgtctgc tctaaccaac tgagctaaag gtccaggctc ttaaaaatcg cggcggaggg
      121 gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc
      181 gaaaaagata ttcattattt aaatgaaatg gagcctagcg ggatcgaacc gctgacctcc
      241 tgcgtgcaaa gcaggcgctc tcccagctga gctaaggccc cgtgtttaaa tttataatta
      301 tcgggaagac aggattcgaa cctgcgaccc cttggtccca aaccaagtgc tctaccaagc
      361 tgagctactt cccgtttaat t
//
LOCUS       DACBZK010000287          366 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.299, whole genome shotgun sequence.
ACCESSION   DACBZK010000287 DACBZK010000000
VERSION     DACBZK010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.299"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            76..>366
                     /locus_tag="IVD66_003047"
     CDS             76..>366
                     /locus_tag="IVD66_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP6147173.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRA"
BASE COUNT          138 a           70 c           68 g           90 t
ORIGIN      
        1 agacaaataa aaaagccatt tatgttacac tcaaattgta atacccgcta aagcatacaa
       61 ggagagtgaa cataaatgac ttatacccat cttacaccaa acgagcttgt aatgatagaa
      121 gcatattttc atcaagaaac tccggttgct atcgttgcga agcagcttaa acgtggacgc
      181 caaacaattt acaatgtcta taactttctc aaatgtggtg gaacagcact tgaatacttt
      241 gaacaataca aagaaaataa gcgacgttgt gggagaaccg aaatcatttt tcctgctgag
      301 gaaaaagaat acattgaaaa aagatcaact gaaggttgga ccccagacgt cattattggc
      361 cgtgca
//
LOCUS       DACBZK010000288          364 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.300, whole genome shotgun sequence.
ACCESSION   DACBZK010000288 DACBZK010000000
VERSION     DACBZK010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.300"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>364
                     /locus_tag="IVD66_003048"
     CDS             <1..>364
                     /locus_tag="IVD66_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147174.1"
                     /translation="EQRVIEEEVQKIKERYEKKRDNAYSLCIEKINNFTKTNQEALSK
                     EKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTTTEVLMERHGQIQQEL
                     QAQIPKWKKEYEIQQQEL"
BASE COUNT          177 a           49 c           65 g           73 t
ORIGIN      
        1 aagaacaacg agtgattgaa gaagaagtac aaaaaattaa agagcgatac gaaaagaaac
       61 gcgacaatgc gtattccttg tgtatagaga aaattaataa ctttactaaa actaatcaag
      121 aagctttatc gaaagaaaaa gaaaacttgt taaaagaacg tataaaagaa cgaaaagaag
      181 agttctaccg aggtttacgt acagataagc taaagattag caaagaatta aatgaacaac
      241 tgaataaact ttatcaaaca acgactgaag ttcttatgga aagacacggg cagatccagc
      301 aagaattaca agcacaaatt ccaaaatgga aaaaagagta tgaaattcaa caacaagaat
      361 tgaa
//
LOCUS       DACBZK010000289          361 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.301, whole genome shotgun sequence.
ACCESSION   DACBZK010000289 DACBZK010000000
VERSION     DACBZK010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.301"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
BASE COUNT          123 a           39 c           58 g          141 t
ORIGIN      
        1 taggactcaa ttgttcatag atgagcattt gtaattaagt tatattataa taaaaaaata
       61 cgaattttag tgacgccatt atattgtttt tatttttcaa ttgtaatatt tcatattact
      121 tccataataa ggagtatttt ctattggaat atcttagctc ttttaaggat ttctcctttt
      181 ttgtttctca ttttttaaga ttatttggat ttcctttaca acaaacttcc acaagtatta
      241 ttgacataga tgtaattgag ggaagggggt tccagtgcta gaataaataa tgaaaagagg
      301 taacaaatgc tagcgttaag aggtgaacaa gtttgattga aagacatgta aatttattaa
      361 a
//
LOCUS       DACBZK010000290          354 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.302, whole genome shotgun sequence.
ACCESSION   DACBZK010000290 DACBZK010000000
VERSION     DACBZK010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.302"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>354
                     /locus_tag="IVD66_003049"
     CDS             <1..>354
                     /locus_tag="IVD66_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP6147175.1"
                     /translation="LSSNLAYTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQ
                     AKLLNQIAKVGYNSTKKSYFYGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEA
                     NLPNILGDKGYISHK"
BASE COUNT          128 a           64 c           57 g          105 t
ORIGIN      
        1 gcttaagttc aaacttagct tacactatca agattattcg atactttttc atcaagaagc
       61 tcaccaaagg tgaactagtc ggaattatag atagttttcc tagtccatta tgtaaaccag
      121 ttagaaatag acaagcaaaa ctattgaatc aaatagccaa agttggctat aactcaacaa
      181 aaaaatctta tttttatggt cttaaaattc atatgatcgt tactaagact ggctttccga
      241 ttacttactc aatcacgaat ccaggtgtcc atgacgtgaa agtgttagag actttatcgg
      301 aagaagcgaa tcttcccaat atcctagggg acaaaggata tattagccat aaaa
//
LOCUS       DACBZK010000291          353 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.303, whole genome shotgun sequence.
ACCESSION   DACBZK010000291 DACBZK010000000
VERSION     DACBZK010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.303"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>353
                     /locus_tag="IVD66_003050"
     CDS             <1..>353
                     /locus_tag="IVD66_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAP6147176.1"
                     /translation="LDIWLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFR
                     KLQSVGLYTKTEHRTVKYLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYK
                     KNRRNGTLFGFSVST"
BASE COUNT          118 a           74 c           71 g           90 t
ORIGIN      
        1 ccttagatat ctggttacga aagaaacggg atacgcaagc agcctatgct ttcttaaaac
       61 gactccataa acagtttggt gagccgaaag caattgtgac cgataaagca ccttctcttg
      121 gctccgcctt tagaaagtta cagagtgtgg gtttatatac taagacagag caccgaactg
      181 tgaagtatct taacaattta atagaacaag accatcgacc tattaaacga cgaaataaat
      241 tttatcaaag tctccgtaca gcctcttcca cgattaaggg catggagacc attcgaggaa
      301 tatataaaaa gaaccgaaga aatggaacgc tcttcggctt ttcggtgtct act
//
LOCUS       DACBZK010000292          322 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.304, whole genome shotgun sequence.
ACCESSION   DACBZK010000292 DACBZK010000000
VERSION     DACBZK010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.304"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..267
                     /locus_tag="IVD66_003051"
     CDS             <1..267
                     /locus_tag="IVD66_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory protein"
                     /protein_id="HAP6147177.1"
                     /translation="DYFLPDEYARNLYHGLHDQLEEKNEENMFYKIVQSFENETAKKL
                     LIQFYEEQATDRLQEYVEKLIKNEEISEMIRKRLLLEAEKAVKE"
BASE COUNT          120 a           40 c           70 g           92 t
ORIGIN      
        1 gattatttcc taccagatga atatgctaga aatctctatc atggactgca tgatcaatta
       61 gaagaaaaaa acgaagaaaa tatgttttat aaaatcgttc aatcttttga gaatgagacg
      121 gctaaaaaat tgttaattca attttacgaa gaacaagcaa cggatcgtct tcaagaatat
      181 gttgaaaagt tgatcaaaaa tgaagaaatt tctgaaatga ttaggaaacg gctgttattg
      241 gaagctgaaa aggcggtgaa agaatgatca ttggaggaat tttctctggc atagccgact
      301 ggtggtcagg tttattcgga ga
//
LOCUS       DACBZK010000293          322 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.305, whole genome shotgun sequence.
ACCESSION   DACBZK010000293 DACBZK010000000
VERSION     DACBZK010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.305"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..267
                     /locus_tag="IVD66_003052"
     CDS             <1..267
                     /locus_tag="IVD66_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory protein"
                     /protein_id="HAP6147178.1"
                     /translation="DYFLPDIYARRLYHNMHDQIEEEAKENIFIKIVQSLDNSTAQKL
                     LIQFYEEKQIDRLQEYLEKLRQNEEITEVIRKRLLLEAEKAVKE"
BASE COUNT          118 a           48 c           66 g           90 t
ORIGIN      
        1 gattattttc tacctgatat ctatgcacgt cgactttatc acaatatgca cgatcaaata
       61 gaagaggaag ctaaagaaaa catttttatt aaaatcgttc aatctttaga caactcaacg
      121 gcacaaaagt tacttattca attttatgaa gagaagcaaa tagatcgttt gcaagaatac
      181 cttgaaaaat tgcgtcaaaa tgaagaaatt acagaggtta taaggaaacg acttttgcta
      241 gaagctgaaa aggcggtgaa agaatgatca ttggaggaat attttccggc atagccgact
      301 ggtggtcagg cttatttggg ga
//
LOCUS       DACBZK010000294          321 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.306, whole genome shotgun sequence.
ACCESSION   DACBZK010000294 DACBZK010000000
VERSION     DACBZK010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.306"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..>321)
                     /locus_tag="IVD66_003053"
     CDS             complement(<1..>321)
                     /locus_tag="IVD66_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP6147179.1"
                     /translation="ITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKH
                     GMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQAR
                     VTSL"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DACBZK010000295          315 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.307, whole genome shotgun sequence.
ACCESSION   DACBZK010000295 DACBZK010000000
VERSION     DACBZK010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.307"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>315
                     /locus_tag="IVD66_003054"
     CDS             <1..>315
                     /locus_tag="IVD66_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147180.1"
                     /translation="TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKS
                     EKGKENILPEVQAIIDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATS
                     EE"
BASE COUNT          132 a           53 c           68 g           62 t
ORIGIN      
        1 tgacgatcga taatattcca agaatcaaag aagaaatcga acgctttgaa aaaggtgaat
       61 cgactttttc agccgccacg atccgaaaat atcaacggaa gttggaaaca ttagaacagc
      121 tgaaagaaaa atcagaaaaa ggaaaagaaa atatcctccc tgaagtacaa gcgatcattg
      181 acagcggacg agtgacgcaa tggaaaaaaa atccaaccat ttattttttg aaaggctatc
      241 gaaaagttgc tttagaactg aatgaaaacg ggggatttga ggaatcaaaa aaataccaag
      301 ccacgtcgga agagg
//
LOCUS       DACBZK010000296          305 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.308, whole genome shotgun sequence.
ACCESSION   DACBZK010000296 DACBZK010000000
VERSION     DACBZK010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.308"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..302)
                     /locus_tag="IVD66_003055"
     CDS             complement(<1..302)
                     /locus_tag="IVD66_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HAP6147181.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT           95 a           45 c           50 g          115 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgtt
//
LOCUS       DACBZK010000297          298 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.309, whole genome shotgun sequence.
ACCESSION   DACBZK010000297 DACBZK010000000
VERSION     DACBZK010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.309"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
BASE COUNT          127 a           37 c           46 g           88 t
ORIGIN      
        1 aaagtattga ttaaagccta tctcaaagtt gtaaaagcta aagaaatatg tcgagaagtg
       61 aatttatcta acacaacaat atctgagttg aagaatggtc gaaagaattt agatacttta
      121 aaattcagat catttgaagc tctatatgta gctgctaaaa aatattttac agctgataac
      181 aaataaaaaa caggagtatt ttatgtgaaa aaagtatata aaaaatgctt atgaatcagc
      241 tatatcacct taaccatttg ttaatgagat gggagaaaac attaaccacg attctaac
//
LOCUS       DACBZK010000298          283 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.310, whole genome shotgun sequence.
ACCESSION   DACBZK010000298 DACBZK010000000
VERSION     DACBZK010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.310"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            1..283
                     /locus_tag="IVD66_003056"
                     /pseudo
     CDS             1..283
                     /locus_tag="IVD66_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          109 a           57 c           56 g           61 t
ORIGIN      
        1 aacaaatcgt cgatctctat ctcgctggta agcctcgcgc agaaattatt cgagagtatg
       61 agcttacgcc ttcttctttc gataaatgga tgaagcaagc acaatcaacg ggctcattca
      121 aagaaagaga caacttaaca ccagaacaag cagaattgat cgcactaaga aagaaaaata
      181 agcaactcga aatggagaat gatattttaa agcaagcggc gctgatattc ggacgaaaag
      241 acaagtaatt gatgccaaca agcataaata ttccatatca gcg
//
LOCUS       DACBZK010000299          278 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.311, whole genome shotgun sequence.
ACCESSION   DACBZK010000299 DACBZK010000000
VERSION     DACBZK010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.311"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
BASE COUNT           94 a           49 c           42 g           93 t
ORIGIN      
        1 tatctttctg gatcaacgaa agtatacttt atatagtcat aacgccgatg atcgctacgt
       61 gcgtccggca cgtcagtcac gatatcaaac aaaaagtata catccttctt cattctagtt
      121 ttcgcagcag gaattttgaa atagttctta ttagaatagt agagattgat taataagcta
      181 tcttcgattg ctaaaaagaa aacttctgaa ttccatactt tataaaaatc tttgataaat
      241 ctattcgaag ggtcaaattt aaaccataat tgtgtctc
//
LOCUS       DACBZK010000300          272 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.312, whole genome shotgun sequence.
ACCESSION   DACBZK010000300 DACBZK010000000
VERSION     DACBZK010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..272
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.312"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>272
                     /locus_tag="IVD66_003057"
     CDS             <1..>272
                     /locus_tag="IVD66_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP6147182.1"
                     /translation="TMKKEFPIPISWTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGV
                     GGGALQEGRFIEGFSHPEMGHMLVVPHPKDDFAGSCPFHGNCLEGMA"
BASE COUNT           66 a           56 c           77 g           73 t
ORIGIN      
        1 accatgaaaa aagaatttcc gatcccgatt tcttggacaa cagatgtcaa tgcggctgcc
       61 tatggtgagt atgtcttcgg cagtggcaaa ggattgagca gtgtcgttta ctatacgatc
      121 ggtacgggtg ttggcggcgg tgccttacaa gaagggcgct ttatcgaagg gtttagtcat
      181 ccagaaatgg ggcatatgct cgtcgtccct catccaaaag atgactttgc tggcagctgt
      241 ccatttcatg gcaactgttt agaagggatg gc
//
LOCUS       DACBZK010000301          269 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.313, whole genome shotgun sequence.
ACCESSION   DACBZK010000301 DACBZK010000000
VERSION     DACBZK010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..269
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.313"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>269
                     /locus_tag="IVD66_003058"
     CDS             <1..>269
                     /locus_tag="IVD66_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147183.1"
                     /translation="PPKIKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAANK
                     ADKTGSPAFQIIQNNVIDVSTLLENDPNKVEHIPTDKRNALTAKN"
BASE COUNT          102 a           42 c           47 g           78 t
ORIGIN      
        1 ccaccaaaaa tcaaaaatat cttggttaat ctatttatgg ccatgatttt gatttttggt
       61 ggtagttctt taatcgatga agggctaaat attagtaaaa acttttacgg agacgtgact
      121 gcagcaaata aagcagataa aactggttca cctgcttttc aaattattca aaataatgtg
      181 attgatgtga gtacgttact agaaaatgat ccgaacaaag tagaacacat accaacagac
      241 aaaagaaatg ctctcacggc gaaaaattt
//
LOCUS       DACBZK010000302          269 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.314, whole genome shotgun sequence.
ACCESSION   DACBZK010000302 DACBZK010000000
VERSION     DACBZK010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..269
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.314"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>269
                     /locus_tag="IVD66_003059"
     CDS             <1..>269
                     /locus_tag="IVD66_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147184.1"
                     /translation="PPKIKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAANK
                     ADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKN"
BASE COUNT          100 a           42 c           45 g           82 t
ORIGIN      
        1 ccaccaaaaa tcaaaaatat cttggttaat ctatttatgg ccatgatttt gatttttggt
       61 ggtagttctt taatcgatga agggttaaat atcagtaaaa acttttatgg agacgtcact
      121 gcagcaaata aagcagataa aacgggttca cctgcttttc aaattattca aaataatgtg
      181 attgatgtca gtacattact agcgactgac ccgaataaag tagaatcctt accaacagat
      241 aaaagaaatg ctttaacagc gaaaaattt
//
LOCUS       DACBZK010000303          266 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.315, whole genome shotgun sequence.
ACCESSION   DACBZK010000303 DACBZK010000000
VERSION     DACBZK010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.315"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            85..>266
                     /locus_tag="IVD66_003060"
     CDS             85..>266
                     /locus_tag="IVD66_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP6147185.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT           84 a           55 c           43 g           84 t
ORIGIN      
        1 tacctatgaa atattttcac gtgttaaagt attcctcgtt gaacacaaca aataaaactt
       61 tttaacgaat aaaggagatt tttcatgaca tcacttaaaa ctttactttt tggaacaact
      121 ttggctgccg gcgctgcatt cttcatggga acgactgctc atgcggacga agcttatacc
      181 gttcaatcag gtgatactct atcaacgatt tctcaaaaat acgttggtga taactccttg
      241 atcaatgcca ttgcagaatc aaattc
//
LOCUS       DACBZK010000304          265 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.316, whole genome shotgun sequence.
ACCESSION   DACBZK010000304 DACBZK010000000
VERSION     DACBZK010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..265
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.316"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>265
                     /locus_tag="IVD66_003061"
     CDS             <1..>265
                     /locus_tag="IVD66_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HAP6147186.1"
                     /translation="KAGFVTEDNLYLDSTHIKANANKHKFTKEMTHDEAKAYQDELED
                     EINRQRIEAGKRPFTLDLEKEVKLKERKISKADPESGYYVKGER"
BASE COUNT          106 a           44 c           61 g           54 t
ORIGIN      
        1 aaagcaggtt ttgtaacaga ggataatttg tatctggatt ctacccacat caaagctaac
       61 gccaataaac ataagtttac gaaagaaatg acccatgatg aagcgaaagc ctatcaggat
      121 gaattagaag atgagatcaa tcgtcaacga atagaggctg gaaaacgccc ttttactttg
      181 gacttagaaa aggaagtgaa gctgaaagaa agaaaaataa gtaaagctga tccggaaagc
      241 ggctactacg tcaaaggcga acgag
//
LOCUS       DACBZK010000305          254 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.317, whole genome shotgun sequence.
ACCESSION   DACBZK010000305 DACBZK010000000
VERSION     DACBZK010000305.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..254
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.317"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
BASE COUNT           95 a           52 c           39 g           68 t
ORIGIN      
        1 acgggtaacc gtttatttcc tattgcaatt ggcattagta ctctctcctt tcatcgaaat
       61 aaccctatta aaaatatggc tgcaatcaac ttgaatatta gactcacaag ggttaacaca
      121 aagcgccaaa agatcaaaca aaataccagt attcctaaga atactacgaa gtttaaatgt
      181 agagctgcac catgacgcat aagtatctcg ccaacaaaca gtacgaacaa tagaggaatg
      241 attttattca tatg
//
LOCUS       DACBZK010000306          251 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.319, whole genome shotgun sequence.
ACCESSION   DACBZK010000306 DACBZK010000000
VERSION     DACBZK010000306.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..251
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.319"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>251
                     /locus_tag="IVD66_003062"
     CDS             <1..>251
                     /locus_tag="IVD66_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147187.1"
                     /translation="VTKVLQDYGNYLQYQDVFSWICNTFLWGLIKGLYNLNTLLEKTI
                     YQSFDLKDLLNAAGVNELFQSLISKVLALFCVVTLIYLG"
BASE COUNT           77 a           28 c           46 g          100 t
ORIGIN      
        1 gtaacgaaag tcttacaaga ttatggtaat tatctgcagt atcaagatgt attcagttgg
       61 atttgtaata cttttttatg gggtttgatt aaagggttat ataatctcaa tactttacta
      121 gaaaaaacaa tttatcaaag ctttgattta aaagacttat tgaacgccgc tggtgttaat
      181 gaactgtttc aaagtttgat tagtaaggta ttggctcttt tttgtgtcgt cacattaatt
      241 tatttaggct t
//
LOCUS       DACBZK010000307          247 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.320, whole genome shotgun sequence.
ACCESSION   DACBZK010000307 DACBZK010000000
VERSION     DACBZK010000307.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.320"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
BASE COUNT           75 a           46 c           51 g           75 t
ORIGIN      
        1 tatgcttgtg atgaattgat tttcgttctg cacttttgga cgataaattt ggacaattga
       61 aaatacaaaa aaaagaaagg cccctgtaag actcgggaga ctggtaatct ccgtcagtgc
      121 cctacaggaa agcattaagc tcactcctta atgcgtgccc ttcagtgtta cggtattacc
      181 cgcaacggat ttagtataac agatattcaa aagtgatacc actttttttg gctgtgttaa
      241 ggttaaa
//
LOCUS       DACBZK010000308          246 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.321, whole genome shotgun sequence.
ACCESSION   DACBZK010000308 DACBZK010000000
VERSION     DACBZK010000308.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.321"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
BASE COUNT           76 a           46 c           63 g           61 t
ORIGIN      
        1 aacaagactt caaacgcttc ttggcgatga ttgatgagtg ccataatggt gcgacctgtt
       61 ctgcagtgaa aagctgtggg ttgcaagtag tctaaaaact attgtaataa ctcttataac
      121 gagaagtcaa atgagtgggt aacgccacaa agggcttcca ctgatactcc gacatgcaac
      181 aagtagttta tgcagaccaa cgttgtgtga agctcggtga agtcggctga aggataccgt
      241 aaggta
//
LOCUS       DACBZK010000309          239 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.322, whole genome shotgun sequence.
ACCESSION   DACBZK010000309 DACBZK010000000
VERSION     DACBZK010000309.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..239
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.322"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            4..>239
                     /locus_tag="IVD66_003063"
     CDS             4..>239
                     /locus_tag="IVD66_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147188.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEK"
BASE COUNT          110 a           36 c           53 g           40 t
ORIGIN      
        1 gacatggcag aagaaaaaga accactagac aatagtcgct tgggaaaatc caaaagaaaa
       61 ttagtacgat tgcaaaatga attaaacgaa caaattgaga agatgtttga acaccagaga
      121 aagaccaacg gtcagccaat gaacgataag agaaatgggc attcttggtt taggcaacaa
      181 gaacgtttag aaaacaaagt gcatagtctg agagaagaga tcaagcaaca agaaaaaca
//
LOCUS       DACBZK010000310          239 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.323, whole genome shotgun sequence.
ACCESSION   DACBZK010000310 DACBZK010000000
VERSION     DACBZK010000310.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..239
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.323"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>239
                     /locus_tag="IVD66_003064"
     rRNA            <1..>239
                     /locus_tag="IVD66_003064"
                     /product="16S ribosomal RNA"
BASE COUNT           56 a           55 c           70 g           58 t
ORIGIN      
        1 gtttaattcg aagcaacgcg aagaacctta ccaggtcttg acatcctttg accactctag
       61 agatagagct tccccttcgg gggcaaagtg acaggtggtg catggttgtc gtcagctcgt
      121 gtcgtgagat gttgggttaa gtcccgcaac gagcgcaacc cttattgtta gttgccatca
      181 ttcagttggg cactctagca agactgccgg tgacaaaccg gaggaaggtg gggatgacg
//
LOCUS       DACBZK010000311          239 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.324, whole genome shotgun sequence.
ACCESSION   DACBZK010000311 DACBZK010000000
VERSION     DACBZK010000311.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..239
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.324"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            16..222
                     /locus_tag="IVD66_003065"
     CDS             16..222
                     /locus_tag="IVD66_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP6147189.1"
                     /translation="MNLIYDEIAIDPYKGEQKTGDLSGIWSSGFKYAGTTYRVAYEII
                     ENKVIPVLLCGTHENFYEQLKKLI"
BASE COUNT           84 a           24 c           51 g           80 t
ORIGIN      
        1 ttgaaagaaa aatttttgaa tttaatttat gatgaaattg cgattgatcc atataagggt
       61 gaacaaaaaa ctggggattt atcaggtatt tggtctagtg ggttcaaata tgcgggcaca
      121 acatatagag tagcttacga gattatagaa aacaaggtta ttccagtatt gttatgtgga
      181 acgcatgaaa acttttatga acagttgaaa aaattaatct agtgatttgt tgtcgttct
//
LOCUS       DACBZK010000312          234 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.325, whole genome shotgun sequence.
ACCESSION   DACBZK010000312 DACBZK010000000
VERSION     DACBZK010000312.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..234
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.325"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>234
                     /locus_tag="IVD66_003066"
     CDS             <1..>234
                     /locus_tag="IVD66_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAP6147190.1"
                     /translation="VKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLNN
                     LIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRG"
BASE COUNT           84 a           48 c           46 g           56 t
ORIGIN      
        1 gtgaagcagt ttgatgaacc gaaggttgta gtcacagata aagccccctc tattacaagt
       61 gcctttaaga aactaaaaga atacggcttt tatcaaggga cagaacatcg taccattaaa
      121 tacctgaata atttgattga acaagaccat cgtccagtaa agagacgcaa taaattctat
      181 cgaagtttac gcactgcctc taccacgatt aaaggcatgg aagccattcg agga
//
LOCUS       DACBZK010000313          224 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.326, whole genome shotgun sequence.
ACCESSION   DACBZK010000313 DACBZK010000000
VERSION     DACBZK010000313.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.326"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>224
                     /locus_tag="IVD66_003067"
     CDS             <1..>224
                     /locus_tag="IVD66_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HAP6147191.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAA
                     ESQTPAKPAAEPTVDTESAGSSSEGVFQFK"
BASE COUNT           70 a           47 c           58 g           49 t
ORIGIN      
        1 ccgtcacctg ttacaggaac ggttaaaaat gtgattgttc cagaaggtac cgtagcaaat
       61 gttggggatg tattagtaga aatcgatgca ccaggacacg aagacaatga aggggacagt
      121 ggtgtagccg cagaatccca aactccagct aaaccggctg ctgaacccac tgttgataca
      181 gaatcagctg gatcgtcaag cgaaggagtc ttccaattta agtt
//
LOCUS       DACBZK010000314          222 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.327, whole genome shotgun sequence.
ACCESSION   DACBZK010000314 DACBZK010000000
VERSION     DACBZK010000314.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..222
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.327"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(<1..190)
                     /locus_tag="IVD66_003068"
     CDS             complement(<1..190)
                     /locus_tag="IVD66_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6147192.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKF"
BASE COUNT           68 a           46 c           27 g           81 t
ORIGIN      
        1 taaattttgt agtgtagctt ttgccacctc caaccaagcc ttcccaacca tgatagttat
       61 aaatccttac ccaatgtcta accagtgtac gatttatttg atatttatgt gcaagatatt
      121 tgtagccgcc ttcgttattt aaatagtctg aaactacttt tttcttaaaa acaaatgtat
      181 atttccgcaa aaaaagcacc ccttttaatt agatttctag tc
//
LOCUS       DACBZK010000315          208 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.328, whole genome shotgun sequence.
ACCESSION   DACBZK010000315 DACBZK010000000
VERSION     DACBZK010000315.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..208
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.328"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>208
                     /locus_tag="IVD66_003069"
     CDS             <1..>208
                     /locus_tag="IVD66_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAP6147193.1"
                     /translation="SYQKHEGEVFKQNIEKKMPVDQINAHAKSYKEDATNVNNDMSLG
                     QMLSIQKEAIEMGVNKQVFAQIQIP"
BASE COUNT           87 a           32 c           43 g           46 t
ORIGIN      
        1 ttagctacca aaaacatgaa ggagaggtgt ttaagcaaaa tatagaaaaa aagatgcccg
       61 tagatcaaat caatgcacat gcaaagagtt ataaggagga tgcaacgaac gtcaataatg
      121 atatgtcttt ggggcaaatg ttgtccatac aaaaagaagc aatcgaaatg ggcgtcaata
      181 aacaagtatt tgcacaaatt cagattcc
//
LOCUS       DACBZK010000316          207 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.329, whole genome shotgun sequence.
ACCESSION   DACBZK010000316 DACBZK010000000
VERSION     DACBZK010000316.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.329"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>207
                     /locus_tag="IVD66_003070"
     CDS             <1..>207
                     /locus_tag="IVD66_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP6147194.1"
                     /translation="AVDIENSINEWLQSVPKNLFKSITFDCGKEFSNWKSISNTNDID
                     IYFADPGTPSQRGLNEHSNGLLRK"
BASE COUNT           74 a           37 c           36 g           60 t
ORIGIN      
        1 ggcagttgat attgaaaatt cgattaatga atggcttcaa tccgtaccca aaaatctttt
       61 caaatcaatt acctttgatt gtggaaaaga attctctaat tggaaaagta ttagtaatac
      121 gaatgatatt gatatttatt tcgcagaccc aggaacgcct tcccaacggg gattaaatga
      181 acattcaaac ggactcctcc gaaaaga
//
LOCUS       DACBZK010000317          202 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.330, whole genome shotgun sequence.
ACCESSION   DACBZK010000317 DACBZK010000000
VERSION     DACBZK010000317.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..202
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.330"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..>202
                     /locus_tag="IVD66_003071"
     CDS             <1..>202
                     /locus_tag="IVD66_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147195.1"
                     /translation="GKSGLSNLNDIRKNGFGNRKDVTPDNGEEQSDDKATTVPNSKKT
                     VSEMFGKAKNGVSKAAEGLGYVN"
BASE COUNT           75 a           28 c           48 g           51 t
ORIGIN      
        1 ggtaagagtg gtttaagcaa tttaaatgat attcgtaaaa atggatttgg taatcgaaaa
       61 gatgttaccc ctgataacgg ggaagaacaa tcagacgata aagctacaac tgtacctaat
      121 agtaagaaaa cagtttccga aatgttcggg aaagcgaaaa atggtgtttc taaagccgca
      181 gaaggtcttg gttacgtcaa tg
//
LOCUS       DACBZK010000318          200 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.denovo.331, whole genome shotgun sequence.
ACCESSION   DACBZK010000318 DACBZK010000000
VERSION     DACBZK010000318.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..200
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.denovo.331"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
BASE COUNT           54 a           39 c           28 g           79 t
ORIGIN      
        1 aaccgcagct actactttcg gttgtgttaa aaaattcatt gtaattgatt caaacataaa
       61 attgttcgct ccttttagtg tttaataatt tcatcgaaaa caagcttttc acgttcacgt
      121 tgatagatat atccttctaa gtccttgtct tttccccgta ataggtcaaa ttgtgctttt
      181 tcaaggactt cttgtttcca
//
LOCUS       DACBZK010000319        23851 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.guided.038, whole genome shotgun sequence.
ACCESSION   DACBZK010000319 DACBZK010000000
VERSION     DACBZK010000319.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23851
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.guided.038"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            342..1556
                     /locus_tag="IVD66_003073"
     CDS             342..1556
                     /locus_tag="IVD66_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAP6147196.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            1587..1805
                     /locus_tag="IVD66_003074"
                     /pseudo
     CDS             1587..1805
                     /locus_tag="IVD66_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2224..2697
                     /gene="dfrF"
                     /locus_tag="IVD66_003075"
     CDS             2224..2697
                     /gene="dfrF"
                     /locus_tag="IVD66_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HAP6147197.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            2824..3480
                     /locus_tag="IVD66_003076"
     CDS             2824..3480
                     /locus_tag="IVD66_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005603505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HAP6147198.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            3662..4192
                     /locus_tag="IVD66_003077"
     CDS             3662..4192
                     /locus_tag="IVD66_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP6147199.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQETGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            4738..4980
                     /locus_tag="IVD66_003078"
     CDS             4738..4980
                     /locus_tag="IVD66_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HAP6147200.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            4977..5447
                     /locus_tag="IVD66_003079"
     CDS             4977..5447
                     /locus_tag="IVD66_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP6147201.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            5575..6789
                     /locus_tag="IVD66_003080"
     CDS             5575..6789
                     /locus_tag="IVD66_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP6147202.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQP
                     LNDELREIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDY
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKEKYKAGECMSYFRMQKDYSGTEKCGSDLPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTAVPQENDGIF"
     gene            complement(7499..7687)
                     /locus_tag="IVD66_003081"
     CDS             complement(7499..7687)
                     /locus_tag="IVD66_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147203.1"
                     /translation="MAVREYHYLTVQVMAIKEDKSFTRTQIGFRSLLQGKGRGVFVST
                     ASCLSNVLNSFIQLSKND"
     gene            7778..7987
                     /locus_tag="IVD66_003082"
     CDS             7778..7987
                     /locus_tag="IVD66_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HAP6147204.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            8099..9712
                     /locus_tag="IVD66_003083"
     CDS             8099..9712
                     /locus_tag="IVD66_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4368 domain-containing protein"
                     /protein_id="HAP6147205.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            9747..10958
                     /locus_tag="IVD66_003084"
                     /pseudo
     CDS             9747..10958
                     /locus_tag="IVD66_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            10981..11907
                     /gene="glsA"
                     /locus_tag="IVD66_003085"
     CDS             10981..11907
                     /gene="glsA"
                     /locus_tag="IVD66_003085"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HAP6147206.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            12115..13575
                     /locus_tag="IVD66_003086"
     CDS             12115..13575
                     /locus_tag="IVD66_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147207.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            13796..15559
                     /locus_tag="IVD66_003087"
     CDS             13796..15559
                     /locus_tag="IVD66_003087"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HAP6147208.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            15643..16101
                     /locus_tag="IVD66_003088"
     CDS             15643..16101
                     /locus_tag="IVD66_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HAP6147209.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            16210..16893
                     /locus_tag="IVD66_003089"
     CDS             16210..16893
                     /locus_tag="IVD66_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAP6147210.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            17040..17654
                     /locus_tag="IVD66_003090"
     CDS             17040..17654
                     /locus_tag="IVD66_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAP6147211.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            17670..17876
                     /locus_tag="IVD66_003091"
     CDS             17670..17876
                     /locus_tag="IVD66_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6147212.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            18417..19547
                     /locus_tag="IVD66_003092"
     CDS             18417..19547
                     /locus_tag="IVD66_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP6147213.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            19639..20394
                     /locus_tag="IVD66_003093"
     CDS             19639..20394
                     /locus_tag="IVD66_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAP6147214.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            20452..22491
                     /locus_tag="IVD66_003094"
     CDS             20452..22491
                     /locus_tag="IVD66_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HAP6147215.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQATRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(22600..23751)
                     /locus_tag="IVD66_003095"
     CDS             complement(22600..23751)
                     /locus_tag="IVD66_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAP6147216.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
BASE COUNT         8213 a         3848 c         4921 g         6869 t
ORIGIN      
        1 caattctgat tcatcagtcc cataaattat agagcccaaa tttgagaacc gtagcgacac
       61 tcgctgcggt tcttttttat atattttata tgaagtattc tttattcctt atgaaaaaat
      121 atctttaaaa ataaaaaaag acgaaaataa acggttttct ataaaaagaa gaccgtttat
      181 tttttgtctt tatttgtgtg aaaaacgaaa aagagcacaa cacatcaagc ttttattaat
      241 tgtctgtctt ttataaatgc aagtattaat tcaaaaaaac agaagaaaaa aacaactaca
      301 ccttctttta tactcgtaat cgtagaaagg aggcgaaaaa aatgaataca ttacctatca
      361 atacaggaga tacagcattc atgattttat gtacagcaat ggtttgcctg atgactcctg
      421 gtctagcttt tttttacggc ggattagcac ggaagaataa tatactaacg atcatgtctc
      481 aatcttttct ctccgttggg ataacaacga ttatgtgggt atttggtgga ttcggattgg
      541 cctttggacg ggatatcggc ggtgttattg gaaacccggc agatttcttt ttgatgagac
      601 atgttacaag cttccccaac atgtttcatg gtgcaacgat tccattttta atgttctttc
      661 tttaccaact gatgtttatc gtgattaccg ttcctttgat gacaggagct tttgcaggga
      721 gattgaattt aaaaggctat attatacttg ttattttttg gaatctgctg atttatttcc
      781 ctgtttgcca ctggatatgg ggtggcggat ttttggatca gatgggattt agagatttcg
      841 ctggtggagc agtcatccac acgacagctg gattcggctc tttagcatgt atcctcacac
      901 ttggtcaaag aaagattcct ttaggagaaa gaagtcagca tagcagtctt atggcagctg
      961 ctatcggtac aggactgctt tggtttggct ggttcggttt taattccggt ggtgcacttc
     1021 gagcagatga acaagcagtc aatgcatttg gttcaacatt catcgctctt gcatttgcga
     1081 tgattacttg gctgatcatt gcaaaagtaa aaggaaatgg ctttgatttt gtcgacgtac
     1141 taacaggatc cgttgctgga ttggcagcca ttacgccttg tgccggttat gtagaagcaa
     1201 aaagtgccat gctgattggg atcattgcgg gtatcgtctg tcatgctgct gttgattttc
     1261 gtaaaaagaa acaatgggat gatgcacttg atgtgtgggg tgttcatggc atgggcggat
     1321 tcacaggtac gattctgata gggatctttg catctaacag ccatttacta acgaatccaa
     1381 gcagctggta cttcttaggg attcaagtga ttggtgtcat cattactgcc gtgtatgcct
     1441 atgtgctgac aacagtgatt ttaaaatcgg cgatgcactt tacaacgatc actactacaa
     1501 aagaagaaca agaagaagga ttggactttt tcttctttgg caacaaactc aattgaaaca
     1561 aattcaaata gaaaagagga agattcatgc aacaaagcaa aacgaaaatt cctgcaaaaa
     1621 aattaacgtt ctttggcttt ttggctatga ccatctcaat ggtcgtttca ttatatgaat
     1681 atcccacatt cgcgacctca ggcttcagct tagtattttt cttgttatta ggcggtttgc
     1741 tatggtttat ccctgtggca ttgtgcgcag cagagatggc aacggtgaaa ggatgggaaa
     1801 aaggtgtttc ccaaacaaaa agatattaag aaacagccca tgtttacctg cttgcaaaca
     1861 aaagaatatt gctactagac taagagatac tacataagtg tgttggtatc tcttttttgt
     1921 tgccgtgaaa cagcagacta tttcatttct gcttgattac cttaaaactt attagtctat
     1981 ggtttgtcaa gggcttgttg cgtgagaaat gctgaatatc accctttaca aaacataggc
     2041 tgataagtaa cttttcaaaa gcagaaaaga aatggcaatg cttataacaa tatgatataa
     2101 tgcagatgaa gacaaaaaag gaatttgtcg agctggttag ttcgagataa ttttgagttt
     2161 gttaagatgt ggtgcacttg atggaatcac aggtacgaca tcatattatg gaggatgaaa
     2221 tagatgatag gtttgattgt tgcgaggtca aagaataatg ttataggcaa gaatggtaat
     2281 ataccatgga aaataaaggg agaacaaaag caatttagag agttaacaac gggtaatgtg
     2341 gttattatgg ggcgaaagtc ttatgaagaa atcggtcatc cgttgcctaa tagaatgaat
     2401 attgttgttt ccaccacaac agagtatcaa ggagataatt tagtttcagt taaatcatta
     2461 gaagatgcat tattattggc taaaggacga gatgtataca tatctggtgg atatggacta
     2521 tttaaggaag ctttgcaaat agtagataaa atgtatatca cagaagtaga tttaaatatt
     2581 gaagatggag atacattctt tccagaattt gatatcaatg attttgaagt tttgataggg
     2641 gaaacacttg gtgaggaagt gaaatatacg agaacatttt atgtaaggaa aaaatgaatt
     2701 gagtaaattt tggatttagg gtgttttcat aaatatattg ctttttatgc atatataaat
     2761 tgttgtaaga caaattccag tttgtatggg gcgataaaat cagaatttga gagaggattg
     2821 aatatgaata aggaatggtc tgaacttaat aaaacaatgc aggcacaaat aaaaaagaaa
     2881 gatacttata agaggggtat tgatacttta cttactttac gaagtcagtt aatacaaacc
     2941 ttagtatctt tcaaagaaga attatgcaga gaagatttta actcaatccc cttcataaac
     3001 gctgatggtt atcatagtaa gacgattgct tattctattt ggcatatttt ccgcattgaa
     3061 gatatagttg tgcatacagt gataaatgaa gatgaacaag tattttttgc aggcaattat
     3121 caagagcgta tcaattcacc tatcattaca acaggaaatg aactcatgaa acagcagatt
     3181 gcagactttt caaaacagct taatctggaa gaattatatt tatatatttt cgaagtatgg
     3241 gaaagcactg agaaaatgct tgaacggtta tcttatgatg aattgaaaag aaaaataccg
     3301 aaagaaagaa aaggatactt agaatcgttg aatgtagtaa acgacaatga aaaagcaatt
     3361 tggctgattg attattggtg taataaagat atttgtggac taattcaaat gccgttttca
     3421 agacattgga ttatgcacac agaagcctgt ttgcgtataa agaacaagat acattcatag
     3481 gcaaaaattt cagtttgtag aactaaggaa attggaattt aaggaggaat aaagtatggt
     3541 tagtgatttt ataagagcag catttccatg gattttaatg ggtttatttg tagcaatcag
     3601 ttgttccctt atgagtaaaa aagagaaata aattcctgtt tgtatttata aaagagaaaa
     3661 aatgagaaaa gtagttttat ttattgccat gagccttgac ggatatattg cggacggtaa
     3721 tggtggagta gcttggctaa atggtcatgg aaatgacaat gaaaacatcg acacttatac
     3781 agaatttacc aaagatatag atactgtctt aatggggtgg aatacttctc atcaggttgt
     3841 tactgaactt tctccgcaag aatgggtata taataaattt acaacttatg tattaacaca
     3901 taaagagtgc aattcttccc aacaaattca ttttacaagt gaaaatcctg ttttattatt
     3961 ggaacggcta aaacaagaaa caggaaagga tatttggatt tgtggcggag caaatcttgt
     4021 tcagcagttg gtaagcaaaa atatgattga taaatattac atttctgtta ttcctactct
     4081 gttaggaaat ggggttcgtc ttttgggcaa catagacagg gaaataaagt taaggctttg
     4141 taaaacacag acttataacg gaataaccga tttgatttat atgcgtagat aactagagag
     4201 aaacagaaaa gctgttaaac cgacggagcg atccgaccac gttggcggga aaatccttaa
     4261 gatttttccg ccatgcttgc aagggggcgg ttcgcttcgg cggttcggcg agcttgcgag
     4321 ccgttcaaag cccccgttat ctaacaaggg gggcacaaaa aacaagaaac actatacact
     4381 aacaagcgga aaacgctgta tttataaggc aaaaccccat ttttacagta gtgatataaa
     4441 ttgtacctat atcactatga aaattgaata gtaaatatga gaaagacagt tgatttcaaa
     4501 aaataagaaa ttgattgtcg ttttcttttg cagaaattta agtgcaggca attatggtag
     4561 ttgtcgtaat tgctgtcagc tcagtgttta tcactgatgg tgtgaaagat ttacggttgg
     4621 agatgttcaa taagattatt ggtgcttaat tatttttatt gtagtgctga tatgagaatg
     4681 ttataattgg ggtataaaac atacaaataa atttgctgaa aaatgaggta tcaaaatatg
     4741 gaaaatgaat tactggaaaa cttaggaaga cttcacacaa ctgaacttgg cgttattaga
     4801 attaaaaaga acttatcttt gaatgtagaa aatgtaattg aatggtgcaa agaaaaaatt
     4861 agcctttcta atgcggaaat cacaagaaaa ggaaaaaact ggtatataac gattgataat
     4921 tgtattataa cggtaaatgc gtacagttat accgttatca ctgctcacaa ggtaaaatga
     4981 taaatttttc tataaaggaa ttaaacgcat ttgcagttat tgggcaggaa gtagaactga
     5041 ctaattatca aaaaaagaat attcagatta gtacacagtt ttggagaaag tttaacagta
     5101 gtttgaaaaa agcgtatctt tcacaatcag gaaattgggt aaaatatgct tttatggaaa
     5161 gaagaaatgg aaaactttat tatttctgtt ctattcccca aagaaccatt accccagagg
     5221 gctttctgta taaagaaata ccgtcttata aatatttggt tgtggagcat attggtgcta
     5281 tggataaaat atatgaaact tatggcaaga tttatgaaga aattattcct agtacatcgt
     5341 atattcctat aaaagatatt atcctacact ttgaaaaata cgattatcgt tttcattgga
     5401 atagtgataa ttcagttatt gaaatttgga tacctattca agattagaag caattttata
     5461 tccatacaca caaagcagtt agtcttagga ttgactgctt tttctataca gatttttaat
     5521 gacaggcaat tatcaattat ggtagttgcc ttttttgatt ggaggaattg aagaatgaat
     5581 gataaaaact ttattgaaga actaagacaa aagcgtgagg aatacggagt aacacaaaca
     5641 aggcttgctg ttgcctgtgg tatcagccgt gaatattaca accgcattga aaaaggaaaa
     5701 cagccattga atgacgaatt aagagaaatc atagaaaaac agattgagcg tttcaatccg
     5761 caagaaccac tattcttatt gattgattac tttcgtgtcc gctttcctac tacggacgca
     5821 ttggcgatta tccgtgatgt attacaactg aaatctaatt acatgcttta tgaagattat
     5881 ggaaaatacg gatatgaaag caaatatgta cttggcgaca tcaatatcat gtgttccatg
     5941 caggagcatt taggtgtttt attggaactg aaaggcaaag gctgtcggca aatggaatgt
     6001 tatctgctgg cacaggaacg ctcatggtat gacttcatgc tggattgtat gacggctggt
     6061 ggtgtgatga aacggcttga tttggctatc aatgataaag caggaatatt ggatattcca
     6121 aagttaaagg aaaaatacaa ggctggcgaa tgtatgtcct acttccgtat gcagaaagat
     6181 tacagcggta cagaaaaatg cggtagcgat ttaccaaaga atacaggaga aaccttatat
     6241 ctcggttcaa caagtagcga attatatatg tgtgcttatc agaaaaatta tgagcagtat
     6301 gtcaagaatg gcacagaaat tgaagatacg gagattaaga accgttttga aatacgcatg
     6361 aagaacgaac gagcctatta tgcggttgta gatttactga cctatcggga cgctgaacgc
     6421 accgcttttt ctatcatcaa tcattatgtc cgctttgttg acagagagga cgacaagcca
     6481 aaaagtcaat ggataacaaa tgatgattgg gcatggtttg taggggaaaa cagagagccg
     6541 atacgcttaa ccacaaagcc agagccttac actttacaaa aagcgttgca ttggctacaa
     6601 agacaagtcg caccaaccat aaaaatggta caggcattag acagagaaaa tcgtacaacg
     6661 atactgaaag atatgattga gcaggcagaa ctaaaagaca agcataaaca tttattacaa
     6721 ttagagaaat caaccataga agaacgtata gataccgctg ttccacaaga gaatgacggt
     6781 attttttaat gtaattgaaa aatttcagat ttagtcagca aagagctgtt ttcattccct
     6841 atgtgaagtg aaagaagaaa aataaatttt ttattaaatc tgcaacaaaa tggctacttg
     6901 cgtacagata tggtgcgaga aaaggaaatc taaacttttt ttgaaaatag gtcattaaat
     6961 cggggcttgc tgtccctata tgaagtgaaa gaagaaaata gttttgaaaa aatgacggaa
     7021 attcgtgatt agtggacagt cttctgtgaa aagaggaaaa acatcatcat tttgtattca
     7081 aacaggcatt agcagttgag tgttgatgtg aaaagatgaa aatactttgt tctcaactta
     7141 acaatttaag gtttccgttc cctatatggt gcaaagaaaa tatttcattc tattgttggc
     7201 agtaacggta tggtttgggt agttagggtg tgaaaaggaa aatattcttt tttcatcatc
     7261 aacttagcaa aatgacattt tctatcccta tatggtgcat gaaaagaagt taaaattttt
     7321 ccatttaaac ttagcaaatg gacgtttgct gtacagatag tagtgaaaaa ggagaaaatc
     7381 aaccgttgat tgccaaaatg aaccgttcca tttgtactaa taatggaaaa agttttggat
     7441 tttggttacg tttctcctct tttccaacgc gatatatagg aaagacgatt tttttctttc
     7501 aatcgttctt tgacaactga ataaagctat tcaatacgtt tgacagacag ctagccgttg
     7561 aaacaaatac gccacgacct ttcccctgca agagcgagcg aaaacctatt tgtgttcttg
     7621 taaaagattt gtcctctttt atcgccatga cctgtactgt cagataatga tactcccgta
     7681 cagccacagc ttgagcatta agagcgtcgc acgcaatggg tacggctaca taagaactat
     7741 gcagaggtgg aactcctgtg ggctatgaca aaagccgttg aattgcttag aaagatttta
     7801 cagaaagggg gtatgtgtta ttgataatgc tgtaaaaaca attcaaaaga aaaatggcaa
     7861 gtgtggcatt ggcaacagag gaaagacaaa gattgtagta aaagagcatt tttccgaaaa
     7921 gggcaaaaca atggaagaac ttctaactga tgtcatgctg gaaaaagcaa agcagacaat
     7981 cgcataaaat cggtgcagtt gtaagaaata gattgaatga caaaaagtac ccgtgttata
     8041 ctttacttgc aagcaggtat tgtaaacacg ggttagttat aaaggaggat aactgacaat
     8101 gaaacaacag atttacaata ctgcacttta tcttaggtta agccgagatg atgaattaca
     8161 gggcgaaagt tccagcatta ccacacagag aagtatgttg cgtttatatg caaaagaaca
     8221 tcatttgaat gtcattgatg aatatattga tgacggctgg tcgggaacaa attttgacag
     8281 accgagtttt caaagaatga ttgaggatat agaggcagga aaaatcaact gtgttgtaac
     8341 gaaagacctt tcccgtcttg gcagaaatta tattatgaca ggacaatata cagaattgta
     8401 tttccctagt cataatgtcc gctacatagc gattgatgac ggtgtagaca gcgaaaaagg
     8461 cgaaagtgag attgcaccat ttaagaacat catcaatgaa tgggtggcaa gagatacaag
     8521 ccgtaaagtc aaatcagcat ttaagacaaa gtttgcggag ggggctcatt acggtgctta
     8581 tgctccgtta ggatataaga aacaccctga catcaaagga aaactgttgg ttgatgatga
     8641 aacaaaatgg attattgaaa aaatcttttc cctagcctat caaggttacg gaagtgcaaa
     8701 aatcacaaag cagttaagag cagaaaaagt tccgacagcg tcatggctaa attttacaag
     8761 atacggtact tttgcacata tctttgaggg aaaacccgaa agtaagcgtt atgagtggac
     8821 gattgctcat gtcaaggcga tattgaaaag tgaggtttat atcggaaaca gtgttcacaa
     8881 tatgcagtct acggtatcgt tcaagagcaa aaagaaagtg cgtaagcccg aaagtgaatg
     8941 gtttcgagta gaaaacactc acgagccgat tattgacaag gaagtgttct atcgtgtgca
     9001 ggagcagata aaatcaagac gcagacagac aaaggaaaag gcaacgccga tttttgcagg
     9061 gcttgtcaag tgtgcggatt gtggttggtc tatgagattt ggaacgaata agacaaataa
     9121 aacgccttac agttattatg cttgcagtta ctacgggcag tttggcaaag gtaattgttc
     9181 tatgcactac attcgttatg atgtgctgta tcaagccgta ttggaacgct tgcagtattg
     9241 ggctaaggca gtacagcagg acgaagaaaa ggtattgaac aagatacaga aagctggcaa
     9301 tgcagagaga atacgggaaa agaagaaaaa ggcaagtaca ttgaagaaag ccgagaacag
     9361 acaaaatgag attgaccgtt tatttgcgaa aatgtatgaa gatagagcct gtgagaagat
     9421 aacagagcga aattttgtga tgttgtccag caagtaccaa aaagaacaga tagaactgga
     9481 acagcagata acaagcctaa gagaagaact aagtaaaatg gaacaggata tgataggtgc
     9541 tgaaaagtgg attgagttaa tcaaggaata ttccgtacca aaggaactga cagcaccatt
     9601 attaaatgcc atgatagaaa aaatcctcat acatgaagca acaacgaatg aggataacga
     9661 aagaatacag gaaattgaga tatattaccg atttattgga agagttgagt aatcaacaag
     9721 agtaatattt ttaactaagg gaaaccggcg gtgtctatac ttgggtcagt cgcacattgg
     9781 gaaaacgatt cggttttgcc gcaatctttt tccaatggtt tgagataaca gttggctact
     9841 tgaccatgct gtatttctta actggtgcat tatcctatgc aacgggtatt ggtgctatac
     9901 aaaacaataa atatctgaaa ttggcaatcc tattgattat tttctgggct attttactct
     9961 cacagttaaa aggaaccaaa tacacttcat tgattgctcg gatcggtttt gtagctggta
    10021 tcttgttgcc agcattagtc ttgtttggct tagggatcca ttatgtcgct tcaggcgctc
    10081 cactacaaac gatactgtct atgaaaacat tgattcctga tttttcgaaa ttgcctacgc
    10141 tggttgtttt tgtttccttt attttagcat atatgggcgt agaaacatct gccagtcatg
    10201 caaatgaaat ggaaaaccct aaaaaggatt atccattagc aatgtttgta ttggttattc
    10261 tggcaatcat tttagatact tttggcggat tgaccgtcgc tactacagta cctcaacatg
    10321 gtttgtctct taatacaggg gtgattcaat cgttagaatt cctattaaga cacattgatc
    10381 caaatcttgc atggattgcg aaaattcttg cgattcttgt ttgtttaggt gtcatcggag
    10441 aaattgcttc ttgggtaacc tctccttcaa aagcacttca cgtagcagca gaagaaggat
    10501 tacttcctga atattttgca aaagaaaaca cacacggtgt tcctgctcat ttgatgatcg
    10561 caaatgggat cgttgcaaca atctgggcag ccgtctttac attaagcggc ggggggaata
    10621 atctttcatt tcttgcagcg atgtcattga ctgttgtaat ctacctgatg ttgtacttta
    10681 tgtttttcgc gggctatttg aagctggttt ttaaagatga cagtcttgaa agagcctatc
    10741 aggttccagg cggaaaagtt gtaaaagtaa tcgttgcttg tttaggtctt ttgacttcac
    10801 tttttgcttt ttgtatctca tttgttccac ctgctagtat cgcagctgga cagcatggga
    10861 tttatgaaac gattctgatt gtttcttatc ttatcgtctt agttattcca tttacgatct
    10921 acgcatgccg tcataaattc cagcatgcag aaaaataaaa aatgaaagct ggttattcaa
    10981 atggaagtaa aagaattaga acaattgatt ggaaaaaatt tccactatta tcaaacagga
    11041 caagtggcgg attacattcc agcattagct gaagtggatc ccaaacaatt aggtatggcg
    11101 atttatgatt tggatacaaa acaactgatt gagggaggag acgccgatgt gcgctttgcc
    11161 atcgaaagca tgtcaaaagt tcccgtattg ttattagcaa tcaaagacaa cggaatagaa
    11221 aaagtctttc aaacaatcaa cacggaacca accggttttg ccttcaattc tatcatgaat
    11281 atggaaatca atcatcgcaa acatccaatg aatccttttg ttaatgcagg agcgattgca
    11341 acaacctcgt tgattgccgg taaagatgca gatgaaaaat ttgagcgaat cttgtcattt
    11401 atgaaagaga tctgtgatga tcctaatatc acattgaatg aagaaatcta tcattctgaa
    11461 tcaagaacag gtgatatcaa tcgctctctt gcttactata tgaaaggtaa tcaaatgatc
    11521 gaaggagacg taccggagat actcgatgct tatttcagac aatgctccct caatgtcacc
    11581 gctacaggca tagcaaaatt agctgctgtg ctggcaaata aaggaattgc tccttggaat
    11641 ggcaaacaaa tcattactga agaaagtgct acaatcgtca aatcaattat gacaactgct
    11701 ggtttgtatg atgaatcagg agagttttcc gtccatgttg gtgtacctgc aaaaagcggt
    11761 gtaggcggcg ggttgatggc agctgtgcca aatcgttacg gcataggtgt cttcagcccg
    11821 gcactagatc catttggtaa cagcgcagct ggtatccaat tgttgaaaga tgtagtcaaa
    11881 gaactagacg ctgacatctt tgaataacca ttcttgaaag aggctggggt aaaagtccaa
    11941 acggctcaaa gctacctaca atgaggctga aattgtgagc ttgtttgact tttgtcccag
    12001 tttctttttt tattggtttt tgaaagggct tttctaaata aaaaggaaac aaaaatacga
    12061 tttacagata tgattaaata aaatcataag aaaaactgga ggcgtgtatc aggaatgctg
    12121 gaaaattaca tcgagcgaaa tatatttaga aaagtgtatc tgtgtgaaca attatttgaa
    12181 ttccaagaaa tagacatcga acaaacagct atttctctaa gggtgactac accaacgatc
    12241 cttcacgatc tagaaagtct agccgagtgt ctagaatatt gtataaaaga acaagtaaga
    12301 gagaagcata agtataaact cgtattcaaa catggtattg ctctttctga gctcacacag
    12361 tttctgtacg gtcaatctta ttttttaaag tttttaagtt attattttaa tggtatattc
    12421 acgagtacag aactggctga tcttgaattt atttctttga gtaaagtata tacaatcaaa
    12481 aaaatcgtat tggatttttt taaagaaaat gattatttga aaaataaaga aatcattatc
    12541 ccagaatttg actcgcggaa catcttgcta gctttagtac gttatgtcaa ttgggaaggc
    12601 tatgaaaata aaaatccgta tgtagaagaa gcttgtaacg agttgattga ttatgtagag
    12661 actcattttt ttaaaagaag atattcggaa gatgaaaagt cctttatcat acgagaaata
    12721 gagatcgcaa tcggaagaaa ggcatttccc cttggactga aagaagaaga taagaaaagc
    12781 gcagaaacga agccgttatt tcaattagtc tgtcaaggat tggaagagca aaaaggaatt
    12841 ctagacttac aagaagaaga tgtctattat attttttctt tgttcaacag tagaaattat
    12901 accaatgaga acatggagct gttaagaaaa gatttcgaag ttgtttataa aaattttgtt
    12961 ctcaatgacc tatcactgaa tgaattgatt ttacagatta ttagtatcgc tgaaatcgac
    13021 gatgcagaaa attttatttt caagcaatcc tttttacaat ttgtccgtac gttgtgggca
    13081 gatggacaag tatttttacc ggaaaggatc tatcttctat cagaaaaaga acaacttctg
    13141 tacggaaaaa ttgtagaaat attggaagag tggaaaaaga aaaatcaaat ccaactaaga
    13201 tggaatgaaa atttcattcg aaaattcgtc aaaagtcttt ctttgatcaa cagtgaacaa
    13261 gcggggagac aggaaataga aatttttgtt gtttcagaaa gttcagtcaa acaatttttt
    13321 tatcgaaccc aatttcattt gtatgcggaa gaaggcatcg ctgaaataaa tcctatttta
    13381 tttcgttcat tagaagaatt gcctgatgaa tgtctatgtg cgaaaaaaag agtggttttg
    13441 tgcgatgctg ctagctatca aaatggatta gaaactgaaa agacaaagat ctatccaatc
    13501 tcattaaaag gtgcaaacat ccatttgtat catattgctc aggaacttca cctattaaaa
    13561 aaacatattt cttgatgaga ccttaattag gagaccttct acaaagcttt ttaattgtct
    13621 gtagaaggtt tttatttgag tcctgattcg tgcgaagatc tacttatata acaagctttc
    13681 tctgaaattt ttttaaaatg ctattgactt agagtcaact ctaagtagta gaatagataa
    13741 agtgtaacaa atctattttc attaaaagaa gatagtacgg aggagagaat gtattatgag
    13801 tacagtatta catgtattgg atgcaatcaa tagccccgca gatgtcaaaa aattatctgt
    13861 tgaggaaatg aaacagttgg cagaagagat gcgccaaaaa atcttgcaaa aggacagcga
    13921 tgtaggtggg cacgttggtc cgaatctagg tgtagtagaa ttaacgattg cgtttcatta
    13981 tgtatttgat tcaccaaagg ataaaatcgt ttgggatgtt tcccatcagt cttatggtca
    14041 taagctttta actggtcgaa aaaatggttt tgaaaaagga cattaccgtg aagtgagcgg
    14101 atattccaac caacatgaaa gtaaacatga ctattttaca gtggggcaca catctacatc
    14161 tatcagctta gcaacaggtt tagctaaagc gagagatctg aagaaagaat caggaaatgt
    14221 ggtagcattt atcggtgacg gctccctaag tggtggctta gcttttgaag gattgaacaa
    14281 tggtggtgtt ttacaatcca atctaatcgt attagtaaac gataatgaga tgtctattga
    14341 tgagaatcat ggcagtttat ataaaaactt agctgagctt cgtcaaacca acggtaaaag
    14401 cagcaataac ctatttaaag caatgggatt tgattatcgt tacgtggata atggaaacga
    14461 tctggaaacg gtgatccgtt tatttgaaga agtaaaagat attgatcatc cgattgtact
    14521 tcacgtccat acggaaaaag gtcgcggtta tcagccggca atcgataata aaatgaaata
    14581 tcattggcat gtaccatttg atctgtccac cggggaggca aagcaagtaa cttctggaga
    14641 aacatttaat atgatcatca tggattattt ggataagaaa atgcaaacaa gtacagctcc
    14701 tattgccgca gtcaatgcag cgataccagg cgcctttgga ctgaaaacat tccaagaaaa
    14761 acatccagat cattattttg acgtggggat cgctgaacag cactctatca ctttcgcttc
    14821 tgctttggct tctcagggag tacgtccagt cgtcttccaa tcaagtactt tcttgcaacg
    14881 ggcatatgat caattatcac atgatttagc gatcaacgag aatccagtga ttattttagt
    14941 cggtggcgga acgatctcag ctagtgaccg aacacaccaa ggaacatttg acattcctta
    15001 cttatcaagt atcccgaaca tcaaatatct tgctccagca acaaaagagg atatgatctc
    15061 tatgctagat tgggcgttcg aacaaacagc gcagcctgta gcaatccgaa ttcctacaca
    15121 tggtgtagaa catggtacag ctatcgcaaa tgattatagt attccagcct atcaaacagt
    15181 aaataatgga ggaaaagtag caattttagc tttaggcggt tttcttgaat taggaaaaga
    15241 aacagtaaaa gcttttagaa aaaaaggaat cgaagcaacg ttgatcaatc caggaacgat
    15301 cacagaaaat gacgtagaaa cattagataa attaaaagaa acacacgaat tagtcatcac
    15361 attagaagat ggtagtttgt caggaggatt tggcgaaaat atcagtcgtt attatggtga
    15421 ttcttcaatg aacgtattaa attttggtgc agagaaagaa ttcacggata gcgttcctgt
    15481 agggcagctt tatgaacgtt atcatttaac accaaaacaa atcgttgaag atagtctgcg
    15541 tgtcttgaat attcaataat tcattatgct caccatccag ataattgttt atactagtat
    15601 ctggatggtt ttttcattat aaaaagcaaa ggggtggatg ttatgtatca gcaagtagaa
    15661 gaatatgtca aaaagttcca agaaaaatat cctagttatc aatcagaaaa attaggtttc
    15721 ttttcatttg gggatacaga aaaaatggca gacgagttga gcgaactagt tgtaaaaaag
    15781 ataaagactg gtacatcaag tggttacgat ctgtataaac aagagaatga gcctttacca
    15841 aaagttggtc aattagacgt ggtcctgaat ggaaaaaatg aaccagtttg tatcatcaaa
    15901 aatataaatg tgaccatctt gccttttagt gaagtcacga aagagcatgc ttggaaagaa
    15961 ggagaagggg atcggacatt agcttattgg cggaaagtcc atgctgagtt ttttaaacat
    16021 gcttataaag aagcgttgaa catagaattt acagaagaga agctggtcgt atacgaagaa
    16081 tttgaagtaa ttttctttta gtaagaaagg tctgctgaaa gaaatagctc attattgtct
    16141 cctgaataga aaagggttac atttttatat gaagctgtat ttttatataa cattactgga
    16201 ggagatattg tggatacact ggaacaaatc aaaggcggag tcgtcgtttc ttgtcaagct
    16261 ttggaaaacg agccgctaca cagttctttt attatgggga gaatggcttt ggctgcaaaa
    16321 gaaggcggag cagttggtat tcgagcaaat acgacagaag atatcaatga aatcaagcga
    16381 atcgttgatt taccggtaat agggattatc aaaagagatt acgatgggtc agaagtgttt
    16441 attactgcga cagaaaaaga agtggaagaa cttttggaga cgcaagcaga aatcattgca
    16501 ctggatgcaa cttctcgtaa acgtccgaca gaaaaaacaa ctgctgaact tgtccaaatg
    16561 attcacgaac acggtcggtt agctatggca gatatttcga cttttgagga agcgcttcaa
    16621 gcgcaagaag atggttttga tcttttgtct acgactttag caggctatac agaatattca
    16681 cgaaagacgc agacacctga ttttgattta ttgaatcaaa tcatagaaca agtcgatatc
    16741 ccagtaatta tggaaggaca tactgactct cctgaacaag tagagaaagc atatgaatta
    16801 ggtgcttttt cagtcgtagt tggatctatt atcacccgtc cgcaattgat cactaaaaga
    16861 tatgtcgaag ccgcaagtaa agcaaataac taaaaaacac gcacggcaca gattcttgac
    16921 aaaaaagaaa aattgataga tagtttaaag cagattctaa gaagatgaaa aaagcattac
    16981 ttttcatttt gtcttcaaga tctgcttttt aacgaatttt atagaaagaa ggcgaaacca
    17041 tgtttgaacg gagtccttca gaattgacag aacgtgaaaa ttacaagttg ctgattggtt
    17101 cagtcatccc tagaccagta gcagtagtaa cgactaaatc agcaaaagat atagtgaata
    17161 tcgcaccctt cagttacttc aatatcgtca gttcgaatcg acccatctta tccttggcga
    17221 tccagagaaa acaagatgca gtaaaagaca cagcaaagaa tattcttgag acaagagaag
    17281 ctgttatcca tatccttgat gaggacaacg tagaagaagt aaataaaaca gcagccaatc
    17341 tgcctaatga ggaaagcgaa ctgtacctga ctgacttgac tttaactgat tcagtaatca
    17401 tttcagtacc agcattgaca gaagcaaaag ttcgttttga aacatcctta tatgaacatg
    17461 tcgagatacg gaataaaaat aaagtaacag ctgatttatt tttgctagaa gtacagaaat
    17521 atcatttaaa tgaaacagtc tatgatgata agacaggaag gatcgatcca agaaaattga
    17581 atgctgtaag ccgtttggca ggaaatgatt atgcagcaat aggagaaatt ttcacgattg
    17641 cacgtcccga ataaaaagga gcactagtta tgttaaaaat aagctataaa ccatcgacag
    17701 attcaaaaga aatgaaaaaa gaatatgaaa cagtgaatga ttttctgcaa gggcagtact
    17761 tagaagttcc gccattgcaa gaccattttg tcgttactac tgttacttta gatggtaagg
    17821 aaatagaaat gccagatcaa acgattagcg gattgtttaa ttactttaac aaataaatat
    17881 ttattccgaa aagtgaaaaa acatataaaa aaacacataa aactaaaaaa ttatcaaaga
    17941 atcctggtgc aactgaaaga atttgcaacg ggattctttc aacttatttg ttattttttt
    18001 ctaaaaaata ttaaagattg ttaaatttca ctatttcatt tcaaattcca ttgcctaatc
    18061 attaggaaaa gtctatcatg aactcgtaaa tagaatatag taataacctt gttaggtgag
    18121 gctcctatac aaacataggc tgttgcccag aaacgtcgaa agtcgccaat gggtaaaaca
    18181 gaaactgttg gattaaggct ttttccaata gctaagaatg ttttctttac gttgtatagt
    18241 gctaaaactc ggacgatgag atgatgctag gtcagaattc ttgttcgaaa aggtttctga
    18301 ccttttcttt atatttttgt gactgactta tttgatgaga caaactcgct cctcacctga
    18361 caagtggatt gctgtgtgag gaggagatgc ggtgaaaaaa gatcgattgg tggattttgg
    18421 gtccttattt gactttgtcc atgatcggtc ttttagaagt atacagtgcc agttcttatc
    18481 gtttattgca agccgatgaa aatacaaaaa gtctattatt gcgtcaacta attttcatat
    18541 ttttgagttg gagcgtgatc ttcttagctc gttcagtcaa actacactat ttacttcacc
    18601 ctaaaatagc aggatacggt ttagccttat cgattttctt tttagtatta gtaagaatag
    18661 ggatattcgg tgtcactgtc aacggcgcac aacgttggat ctctctgttt ggcattcaat
    18721 tccagccttc tgaactggca aatctttttt tgatttttta tttaagctgg ttttttcgtg
    18781 acggaaatag tagcccaaaa gatctaaaaa aaccattcct gattacagta ggtataactt
    18841 ttctgatttt atttcagcca aagattgctg gagcattgat gatcctttcg attgcgtggg
    18901 tcatattttg ggcagcggcg gttccattta aaaaagggat ctatctaatc gttacttttt
    18961 ctgcattgct gattggagca gcaggcgggg tattatattt aggaaataaa ggttggcttc
    19021 cacagatgtt taatcatgct tatgaaagga tcgcgacttt aagagattct tttatcgata
    19081 gtcatggtgc gggctatcaa atgacccatt cgttttatgc actatataat ggtggcatat
    19141 ttgggcgggg attaggaaat agtatcacaa aaaaagggta tcttccagag acagaaacag
    19201 attttatttt ttcgattatt acagaagagc ttgggctaat cggtgcattg tgtgtgcttt
    19261 tcttattgtt ctcattatgc atgagaatct tttgtttaag cagtcgctgt aaaaatcagc
    19321 aagctggatt gtttctttta ggattcggaa ctttgctatt cgttcagacg ataatgaacg
    19381 tgggaagtat cgcggggctg atgccaatga ctggtgtgcc attgccattt gttagctacg
    19441 gaggaacaag ttatctgatc ctttctttag gaatcggaat cacgttgaat atttcttcaa
    19501 agatacaggc cgaagagttg gcgctctatc gacctgaaaa acaataaaga gaaactgaga
    19561 aactctcagt ttgaattatc ataaagtaca atcttttatt tttcaagcga gaggttcttt
    19621 tagaaagagg aattcgcaat gaaagtatct caaaaaatca tattatctat tttgttactg
    19681 cttacattag tagttggcta tttttcgatt gagtttatcc atggattttc gtctgcaaaa
    19741 cagagttcaa ctgtgaaaaa ggtagagccg aaaagtatcc ctaccacact aaatgtggct
    19801 ttgattggtt cagatgctcg ttcgaaagac gaaaacggtc gctcggattc acttctggtt
    19861 gcacaataca accagaaaac acaacaagca aaactgatct ctatcatgag agattcatat
    19921 gtcgatattc caggttacgg aatgaataag ataaatgcag cttactctta tgggggagtt
    19981 gatttattaa atcaaacatt aaaggaaaat ttcaaatttg aagctcccta ttatgcaagt
    20041 atcacatttc aagattttat cgattgcgtt aatgaactgt ttcctggtgg agtcaagatc
    20101 gatgcagaaa aatctctaga tttagatggc gtatatataa acaaaggaga gcaagtgatg
    20161 gatggtaata ctttactcca gtatgctcga tttcgggaag acaaagaagg agacttcggg
    20221 aggatcagaa ggcagcagca agtgatcaaa gctatctctc agcagctgaa agacgtaact
    20281 tcaatattca agctacccaa agcggttggg aaattacttg gtagtatcca aacgaacctt
    20341 ccagaaagtg tgcttctgga ttgtggtatg gatttcctca aagacatatg ttagaataaa
    20401 caggtataaa tagtgaaata aaggaatgac aagcaagaga aggaggaaaa aatgaaaaga
    20461 agtgacaagc acggcaaaaa tcgaacaggc gcttatattg ccggcgcagt gatcttaata
    20521 gcagctgcgg gtggcggtta tttttactac cagcactatc aagaaaccca agcagtagaa
    20581 gctggagaaa agacagttga gcaatttgtc caagctttga acaagggaga ttataacaaa
    20641 gctgcagaaa tgacatcaaa aaaggcggca aataaaagtg cattatctga aaaagagatc
    20701 ttagataaat accagaatat atacggtgct gctgatgtca aaggacttca gatatcgaat
    20761 ctaaaagtag ataaaaaaga cgattctact tacagttttt catataaagc aaagatgaat
    20821 acctcattag gtgaattgaa agatctttct tataaaggaa cattagacag aaatgatggt
    20881 caaaccacga tcaactggca acccaacttg gtttttccag aaatggaagg aaatgacaaa
    20941 gtaagcctga ccacacaaga agcagcaaga gggaatatta tagatcgaaa tggtgaacca
    21001 ttagcaacaa caggcaaact aaaacaatta ggagtcgttc caagtaaact tggagatgga
    21061 ggcgaaaaaa cagccaatat caaagcgatt gcttcctcct tcgacttaac agaagatgct
    21121 atcaatcagg cgatttcaca aagctgggta caacccgatt actttgtccc attgaaaatc
    21181 attgatggag caacgccaga acttccagct ggagctacca ttcaagaagt agacggcaga
    21241 tattatcctt tgggtgaagc agctgctcag ctgattggtt acgtgggaga tatcacagca
    21301 gaagatattg ataagaatcc agaattaagc agtaatggaa aaatcggtcg ctcaggtttg
    21361 gagatggctt ttgataagga tcttcgtggg acaacaggtg ggaaattaag cattacagat
    21421 gcagacggtg tagagaaaaa agttctgatc gaacatgaag ttcaaaatgg caaagatatc
    21481 aaattgacaa tcgatgcgaa ggcacaaaaa acagcttttg acagtctagg aggaaaagct
    21541 ggatcaactg ttgcgacaac gccaaaaacc ggtgatcttc ttgcgcttgc tagctctcca
    21601 agctatgatc caaacaaaat gacaaacggg atctcacaag aagattacaa agcttatgaa
    21661 gaaaatcctg aacatccatt catcagccga tttgcgacag gttatgctcc tggatctacg
    21721 tttaaaatga ttacagcagc aatcggtctc gacaacggca ctatcgatcc aaatgaagtg
    21781 ttgacgatca acgggcttaa atggcaaaaa gacagttctt ggggatctta tcaagcaacg
    21841 cgtgtcagta gtgatgtatc acaagtagac ttaaaaactg ctttgatcta ttccgataat
    21901 atatatgcgg cacaagaaac gttgaaaatg ggtgagaaaa aatttcgtac aggcttagat
    21961 aaattcattt ttggtgaaga ccttgatttg ccaattagta tgaatccagc acaaatttct
    22021 aatgaagata gctttaactc agatatcttg ctagctgata ctggatatgg acagggcgaa
    22081 cttctaatta ctcctatcca gcaagcagca atgtattctg tttttaccaa caatggcaca
    22141 cttgtctatc ctaaattgat tgcagataaa gagacaaaag ataagaagaa tgtcatcagc
    22201 gaaacagcag tacaaacgat cgtgccagat ctgagagaag ttgtgcaaga tgtaaatggt
    22261 acagcacatt ctctttctgc tttagggatt ccgttggcag cgaaaactgg tacagcggaa
    22321 atcaaagaaa aacaggatgt aaaggggcaa gagaacagtt tcttgtttgc tttcaatctt
    22381 gataaccaag gttatatgat ggtcagcatg ttggaaaata aagaagatga tgattcagca
    22441 accaaacgag catcggaact attgcaatac ctcaaccaaa attatcaata aaaaattgct
    22501 ttttaagtac agtaaaagga ctgtggcgtt atcgtcacag tccttttttc aaataaacgg
    22561 ttttcacgat gtctctttca caacttcttt ttgatttact cacacttcat aaactttttt
    22621 tgtaaaatat ttgagaacaa gtggagaaat aagtgtactt aataaaatca cgataactaa
    22681 aggtgaatag tactgtggtt cgatcaattg actttgctgt ccaatttgta aaatgatcaa
    22741 agccatttct ccacgcgaaa tcataccagc accgaccatc aatgaactat gttgagaaaa
    22801 accggcaatc tgagcaccaa aataacctcc aagcaatttg gtcaaaatcg ctacaagcgt
    22861 caatatagaa ataaagagta gttgttcact aaagtcagaa aaatcaactt ctaatcctac
    22921 actgacaaaa aatactggta taaatactgc atatcctaaa gcctctacat tgtggtatac
    22981 ttcttcttta acctttgtct gactgacagc tatcccagca aaaaaagcac caatgacaga
    23041 gctaagccca acaagatccg ctacgtaaga cattcctaaa caaataacta gcgatacgat
    23101 gataatagaa gaatttgcgt acactttttc tgcaaatgaa agtaggaaag gcgcaatcca
    23161 tttgactaat aagaaaataa aaacaaaata aattagctgt tcaatcaaaa caagcggtaa
    23221 agaagcattg ctagaagctt cccccgttag aaaagatagg ctgaaactta gaactaaaac
    23281 gactaaaatg tcatctacca cagaagcacc caaaattgtt gatccttctt ttgtattcac
    23341 tacgtttagt tcttttaata cttctactga aatactgaca gaagttgccg caagaataat
    23401 cccaaagaaa atcgcttcat ttcccgaaac ttggaatgct ttgcctgtca accagccaaa
    23461 aacaaccggg aagatgatcc caagcaaagc aacgaacata ccaggtcgga aatatttttt
    23521 caaaagagat aaatcacttt ccagaccagc taaaaacatt aataagatca caccaatctc
    23581 cgaaaagtca tggactagaa tatcaggttt gacccaattc aatccagctt ggcctagcaa
    23641 aacaccaaca agtaattgtc caatcactgc tgggatacct aatctccgcg agatatgtga
    23701 gccaatcgtt gttgaaatca atatcaggca taaaatacca ataaattcca ttctcatcat
    23761 tcctttgtat aaaatatagc ccgaacttag cataacatac attattgaaa aaataggaaa
    23821 atatactcac aaaaaaacca acaatccaaa a
//
LOCUS       DACBZK010000320        21088 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.guided.046, whole genome shotgun sequence.
ACCESSION   DACBZK010000320 DACBZK010000000
VERSION     DACBZK010000320.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.guided.046"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            54..1973
                     /gene="tet(M)"
                     /locus_tag="IVD66_003096"
     CDS             54..1973
                     /gene="tet(M)"
                     /locus_tag="IVD66_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HAP6147217.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIV
                     NTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRL
                     NSRIDKVRYMFNKIT"
     gene            2071..2259
                     /locus_tag="IVD66_003097"
     CDS             2071..2259
                     /locus_tag="IVD66_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP6147218.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(2317..2670)
                     /locus_tag="IVD66_003098"
     CDS             complement(2317..2670)
                     /locus_tag="IVD66_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6147219.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            3201..3623
                     /locus_tag="IVD66_003099"
     CDS             3201..3623
                     /locus_tag="IVD66_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP6147220.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            3620..3850
                     /locus_tag="IVD66_003100"
     CDS             3620..3850
                     /locus_tag="IVD66_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6147221.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            4348..4548
                     /locus_tag="IVD66_003101"
     CDS             4348..4548
                     /locus_tag="IVD66_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP6147222.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            4575..5768
                     /locus_tag="IVD66_003102"
     CDS             4575..5768
                     /locus_tag="IVD66_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6147223.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(5836..7401)
                     /gene="guaA"
                     /locus_tag="IVD66_003103"
     CDS             complement(5836..7401)
                     /gene="guaA"
                     /locus_tag="IVD66_003103"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAP6147224.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(7460..8383)
                     /locus_tag="IVD66_003104"
     CDS             complement(7460..8383)
                     /locus_tag="IVD66_003104"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAP6147225.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            8579..9184
                     /locus_tag="IVD66_003105"
     CDS             8579..9184
                     /locus_tag="IVD66_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP6147226.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            9492..10508
                     /locus_tag="IVD66_003106"
     CDS             9492..10508
                     /locus_tag="IVD66_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6147227.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            10649..11950
                     /locus_tag="IVD66_003107"
     CDS             10649..11950
                     /locus_tag="IVD66_003107"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HAP6147228.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            11996..12658
                     /gene="deoC"
                     /locus_tag="IVD66_003108"
     CDS             11996..12658
                     /gene="deoC"
                     /locus_tag="IVD66_003108"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HAP6147229.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            12679..13077
                     /locus_tag="IVD66_003109"
     CDS             12679..13077
                     /locus_tag="IVD66_003109"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HAP6147230.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            13143..14225
                     /locus_tag="IVD66_003110"
     CDS             13143..14225
                     /locus_tag="IVD66_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6147231.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            14437..15999
                     /locus_tag="IVD66_003111"
     CDS             14437..15999
                     /locus_tag="IVD66_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6147232.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            15992..17125
                     /locus_tag="IVD66_003112"
     CDS             15992..17125
                     /locus_tag="IVD66_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6147233.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            17125..18081
                     /locus_tag="IVD66_003113"
     CDS             17125..18081
                     /locus_tag="IVD66_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6147234.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            18180..19346
                     /gene="deoB"
                     /locus_tag="IVD66_003114"
     CDS             18180..19346
                     /gene="deoB"
                     /locus_tag="IVD66_003114"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAP6147235.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            19370..20188
                     /locus_tag="IVD66_003115"
     CDS             19370..20188
                     /locus_tag="IVD66_003115"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAP6147236.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            20205..20912
                     /gene="deoD"
                     /locus_tag="IVD66_003116"
     CDS             20205..20912
                     /gene="deoD"
                     /locus_tag="IVD66_003116"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAP6147237.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
BASE COUNT         6788 a         3757 c         4517 g         6026 t
ORIGIN      
        1 tttatcactg ggatttttat gcccttttgg gtttttgaat ggaggaaaat cacatgaaaa
       61 ttattaatat tggagtttta gctcatgttg atgcaggaaa aactacctta acagaaagct
      121 tattatataa cagtggagcg attacagaat taggaagcgt ggacaaaggt acaacgagga
      181 cggataatac gcttttagaa cgtcagagag gaattacaat tcagacagga ataacctctt
      241 ttcagtggga aaatacgaag gtgaacatca tagacacgcc aggacatatg gatttcttag
      301 cagaagtata tcgttcatta tcagttttag atggggcaat tctactgatt tctgcaaaag
      361 atggcgtaca agcacaaact cgtatattat ttcatgcact taggaaaatg gggattccca
      421 caatcttttt tatcaataag attgaccaaa atggaattga tttatcaacg gtttatcagg
      481 atattaaaga gaaactttct gccgaaattg taatcaaaca gaaggtagaa ctgtatccta
      541 atatgtgtgt gacgaacttt accgaatctg aacaatggga tacggtaata gagggaaacg
      601 atgacctttt agagaaatat atgtccggta aatcattaga agcattggaa ctcgaacaag
      661 aggaaagcat aagatttcag aattgttctc tgttccctct ttatcatgga agtgcaaaaa
      721 gtaatatagg gattgataac cttatagaag ttattactaa taaattttat tcatcaacac
      781 atcgaggtcc gtctgaactt tgcggaaatg ttttcaaaat tgaatataca aaaaaaagac
      841 aacgtcttgc atatatacgc ctttatagtg gagtactaca tttacgagat tcggttagag
      901 tatcagaaaa agaaaaaata aaagttacag aaatgtatac ttcaataaat ggtgaattat
      961 gtaagattga tagagcttat tctggagaaa ttgttatttt gcaaaatgag tttttgaagt
     1021 taaatagtgt tcttggagat acaaaactat tgccacagag aaaaaagatt gaaaatccgc
     1081 accctctact acaaacaact gttgaaccga gtaaacctga acagagagaa atgttgcttg
     1141 atgccctttt ggaaatctca gatagtgatc cgcttctacg atattacgtg gattctacga
     1201 cacatgaaat tatactttct ttcttaggga aagtacaaat ggaagtgatt agtgcactgt
     1261 tgcaagaaaa gtatcatgtg gagatagaac taaaagagcc tacagtcatt tatatggaga
     1321 gaccgttaaa aaatgcagaa tataccattc acatcgaagt gccgccaaat cctttctggg
     1381 cttccattgg tttatctgta tcaccgcttc cgttgggaag tggaatgcag tatgagagct
     1441 cggtttctct tggatactta aatcaatcat ttcaaaatgc agttatggaa gggatacgct
     1501 atggttgcga acaaggatta tatggttgga atgtgacgga ttgtaaaatc tgttttaagt
     1561 acggtttata ctatagccct gttagtactc cagcagattt tcggatgctt actcctattg
     1621 tactggagca agcctttaga aaagctggaa cagaattgtt agagccatat cttagtttta
     1681 aagtttatgc accacaggaa tatctttcac gggcatataa cgatgctccc aaatattgtg
     1741 caaatatcgt aaatactcaa ctgaaaaata atgaggtcat tattattgga gaaattcctg
     1801 ctcgatgtat tcaagattat cgcaatgatt taactttttt tacaaatggg cttagtgttt
     1861 gtttagcaga gctaaaagga tatcaggtta ccactggcga acctgtttgc cagacccgtc
     1921 gtctaaatag tcggatagat aaagtaagat atatgttcaa taaaataact tagtgcgttt
     1981 tatgttgtta tataaatatg gtttcttatt aaataagatg aaatattctt taatatagat
     2041 ttgaattaaa gtggaaagga ggagattgtt attataaact acaagtggat attgtgtcct
     2101 atttgtggaa ataaaacaag actacgaata cgagtggata ctatacttaa aaatttccct
     2161 ttatactgcc ccaaatgtaa gaacgaaact ttaattaatg ttcaaaaaat gaatataata
     2221 acaatcaaag agccagacgc caagacgcag agccgataat ttgagaaatg aaactctcat
     2281 cttatcggct ctttttgttt atctgaattt tactgactag ccttcaatat ttcttgcttc
     2341 attgatacct tttgctagtg cttccattaa ggatagttct ttgtctgtaa agctatccat
     2401 gtatttttct acctgtaacc ttcgagtgct tttaatcaaa ttatctgtag gtaagaaaaa
     2461 ttcatcaata gatacatgga gtaatgatac aagatcatac agcacttgtg tacttgggtg
     2521 ttgtcctttg ttttctatat ttgttaaata acgtgggtca atttcaatca ttgttcccac
     2581 ttgttcacga gtgagacccc gtttcattcg agcctcttta atcgctaaac caacggctct
     2641 aaaatcgtat ttatcttctt ttttacgcat actaaatcac ctctatacat tttactgttc
     2701 ctatataacc ataaacaggt atagaaaaac atgttatata gtttatgagt tcctatagaa
     2761 cactgtggaa tttattaatg cgatgaatcc aatttcaaat agaaaggtcg ctgattttat
     2821 ttacctatac aactttataa aatttagtca tactcctaga aagtagataa aattggcgac
     2881 ttaatggagg gaaaagtcgc catgagaaag ataatctgtc atctagttct cttaattaag
     2941 ttcttatcaa aaaaacttat ccacctgtac tggatagata tgaccatcaa tgtggttttg
     3001 cagattacat agatagaaaa atcaaagcat atgaacagag aaaacaatct gtttatgtgc
     3061 ttttttggtc acttaataaa tatcttttag gatttctctt catttatgca acaaatcccc
     3121 ctttcgtgtc ggggtttagt atgaagggag ataaagaagc acatgccact ccctttcacg
     3181 acagaaaggg ggtgaaaagc atgaaaccat cttcttttca agaaaccata gaaaatcagt
     3241 ttgactatat ctgcaaacaa gttattgaag atgaacgaaa agattacttc aaacatctag
     3301 acagactatc agcaaaagaa gtctcgtttt ctgatataga taactacctt gtcaactctt
     3361 tttctactgt tgatacgtac gtcactgatt tccaactatt taaattattt ggattaagaa
     3421 tcaatgttga aagtgattta ttaagtgaag ccctgcgtca tctttcagag aaaaaacgga
     3481 acattatttt acttcattac tttatggata tgagtgatgt ggagattgcg gagttactaa
     3541 atttgaatcg ttcgactgtt tatcgtcatc gaataagtgg actagccatg attaaagaat
     3601 tcatgaagga gtgtaaagaa tgaaaacagc ttatccaagg gttcccttcc ccctcattgt
     3661 aaaggcgaca gatggcgacg tggaagcaat taatcagatt gttaaacatt atcgagggta
     3721 tacctcaaaa cgttcattac gtcgcatgac agacgaatat ggaaattctc atatggttat
     3781 tgatgaaacc ctacgtggca gaatggaaac gaaactcatc tctaagattt tatcgttcga
     3841 aattaaatag tcccattttt tcgtggaagc gtgtcgaatc gtatccacgc ttcccgattt
     3901 gggaggtttg ttattccatc aaagcatatt gtgtgttcag taggttttga taggctaaca
     3961 agccaaacgt tctttgacaa ccaaataaag gcaatcgaat acgtttcggt aagaaaagag
     4021 ctgatgaact aacacgccat gacctacaaa attagtgagc gattcatgtt agtaattcga
     4081 aagtaatctt tagcaggatt gctgccatga ctttcttatc gtgataatga tactcccgta
     4141 tagccatagt ccgagcgtta gaagcgtcac aggcaatggg tacggctaca tgagaaccat
     4201 gcagaagtga aattcctgtg agctttgcta gagctgttcg attgctaaga tattcttctc
     4261 ttgtcagtgt attattataa aactatttga tataattata ggtgaatatt ggagttttcc
     4321 tagcctataa ttgggaaagg agtaataatg ataacggtca caaaaaagga tttagttgag
     4381 ctaggatatg gaacttcttt ttcagcagac atcataaaaa aagcaaaaga attgatgatt
     4441 acaaaagggc atatctacta tcaatctcga aagctagata gagtccctcg tgaagctgtt
     4501 gaagaaattc taggaattcg gttttcaaat gaaaacaggt ctgagtagtt tttgcacagt
     4561 aaggagtaaa aactatggtt aaagacccaa taaaaaaagc aaagaatgga acctattatt
     4621 ttcgtgcaaa tctaggttat gattctaaag ggaaaaaaat tcaaaaatat cgtagtggat
     4681 tcactactaa aaaagaagca agagaagaat attcgaaact gctattgatg aaaccagaag
     4741 aattaagtga gaataaggat aaaatgacgt ttaaacatta tatctttgaa attttccttc
     4801 catggtataa gacacaggta aagctcagaa catatgaaaa tcgcttacca actattaaga
     4861 agcatttctc ttattttgat aaaatggctg tttccgatat tgagcctatt gatgtgcaaa
     4921 attggcaact aaaattatca aagaagtgta agtcttctta tgtaagagct gttcaaggac
     4981 tattttcagt tgctatggat cgagcaattg tccttgggat aaccaccaca aatccatcta
     5041 agattattgg caatgtgaaa aagcaaaagt ctaaaattga attttggaca aaagaagaat
     5101 ttgaaaaagt aatctctcta atttacaaag aagattacta tcaacacttt ttatttatct
     5161 ctctgtggtt tttatttatg actggaatgc gaattggtga agctactgcc attcaatggg
     5221 aagatattga ttttgactca ggagtactaa ccatcaacaa aacactctat tacaagaatc
     5281 aatcgaatta tagatttgtt gaaccaaaaa caaaggcgag cgttcgtcat attgtattag
     5341 ataaatgcac attaacttat ttatccgaat ggaaggaagt acaacaaaat ctaattcaga
     5401 cagactttgt aatgagctat aacggtattc ctacccaaaa acatacacta tcatatgcta
     5461 ttgaacgcta tgctaagctg gctggtatcc atcgaatcag aatccatggg ttacggcatt
     5521 ctcatgcttc cttgttaatc agtatgggag aaaatccact tatcattaaa gatcgtctag
     5581 gacacgaaga tattgagacg actttaggaa cgtatggaca tctttatcct aacagtaatt
     5641 tcgaggtagc taacaaatta aatggagcca tttcctttaa agaagcaaaa caaaattatg
     5701 atacttcacc aaagaatcaa tttactgtag actacttgcg aaacaaagaa atgaaaaaag
     5761 tgcaataaaa gtgcagtaaa aagataagaa gagccagaaa cccttggtat aagaggattt
     5821 ctagctctcc tacaactatt cccactccac tgttgctggt ggtttagaag tgatgtcata
     5881 cacgatacgg ttgacgtggg ctacttcgtt tacgatacgt acagagattt tttgcaagac
     5941 ttcccatggg atacgggcaa agtcagcggt cattccgtcg attgaagtta cagcacggat
     6001 accgactgtg tagtcgtaag tacgtccgtc acccataaca ccgacagagc ggatccctgg
     6061 aagaacagtg aaatattgcc agatatcacg gtcaagtcca gcagctgcga tttcttcacg
     6121 caagatagca tcagattcgc gtacgatttc tagcttgtct tcagtgattt cgccaagaac
     6181 acgaatacca agaccaggac cagggaatgg ctgacgccaa acgattgaat caggcatgcc
     6241 taactgagtc cctaattcac ggacttcgtc tttgaataat gtgtttaatg gttcgatcaa
     6301 ttcaaattgc atatcttctg gcagtccacc tacattatgg tgagatttga tcgtctgtgc
     6361 tgtttctgta ccagattcga taacgtcagt atacaacgtt ccttgtgcta ggaaagagac
     6421 gccttcttca ccagcaagtt ttgttgcttc gtcatcaaaa acatatacga attcattccc
     6481 aatgatttta cgtttttgtt ctgggtcaga tacacctttc aacttgtcta agaagcgatc
     6541 tcttgcatcg actttgatga tgttcaagcc gaattttccg cctagacttt ccattacttg
     6601 ttccgcttcg cctttgcgta gcagaccgtg gtcaacaaag atagatgtca attggtcacc
     6661 gatcgctttt tgtaaaagaa ccccaacgac actagaatca acgccacctg aaagaccaag
     6721 caagactttt ttgtcaccaa cttgttcacg gattttttct acttgcatat cgataaagtt
     6781 atccattgtc cagttacctt cacagtgaca aacatcaaag gcaaagtggc gcagcaattc
     6841 gattccgtat tcggaatgac gtacttctgc atggaattgg ataccataaa aattacgtgt
     6901 tgtgtcttgg atagaagcaa tcggacaatc tttgcttgtt ccgactgttt caaagccttc
     6961 aggaacttta gttaccaagt caccatggct catccatact gtttgttgtt ttggtgtttc
     7021 tttaaacaag acagcttgat cgcttgttac ttctaacaag gctttcccat attcgcggtt
     7081 tttagcaggc tctacggaac cgccaagttt gtacgtgatc aattgcatac catagcaaat
     7141 ccctaataca ggaataccta aattgaagat ctcaggatcg atcccaaatg cattctcatc
     7201 atatacactg tttggtccgc cagaaagaat gattcccttt ggattcatcg cttttacttc
     7261 ttctgcagta atgcggtggc tcaataattc ggaaaagact ccaagatcac gaatacgtct
     7321 tgtgatcaat tggttatact gactaccgta gtctaatacg ataatctttt caacgttcgt
     7381 catatcggca acgtttgtca aatttattac ccctatccct ttaaatttta tctcaaaata
     7441 gtcaaactat tttaaaatgc taatattttc gcatgaaaat cgaatcgatg atatgatttt
     7501 cagttttatg gagaattata tcggctcttc ctcgtgtagg caagatatat tcctgtaaat
     7561 ttttcaaatt cacatttttc catacatctt ttgccatttt aaaggcttct tcacgatctc
     7621 cgatagcaaa acgataataa taattctctg gattttggaa agccgtatcc agtaacgcac
     7681 caaaacgatc caaataccat ttttcgatca gcacgggatc ggcatcgaca tagacagaaa
     7741 aatcaaaaaa gtcgctgacg tagatttgct gattcgcagg taattgaagc gtattgatcc
     7801 cctcaacgat caagatatca ggctgctgga tcaattcgta cttgtctgga atgatatcat
     7861 acacatcatg tgagtaaaca ggtactttta tctcttcctg accagatttt acacggttca
     7921 agaaatcgat cagcatctcc atatcataac tttcaggaaa tcctttacgg tccatgattc
     7981 cacgctcttt taatatacga tttggataaa gaaatccgtc agtcgtgatc agctgaacgt
     8041 ttcttcgttt gaaggtacga gacaaaatcg tctgcagcag tctggctgtt gtactttttc
     8101 caacggctac acttccggcg atcccgataa taaaaggcgg tacttctacg tatttatgaa
     8161 gaaataaacc tttactcaag aacaaagatt caaattcttt catataaaga taaatcagat
     8221 gagcaagagg tacatagata tctcgaacat cctgcatgga aatgcggtca ttcaaacttt
     8281 tgatattatc tagttcatct tgtgtcaaag gtgcttgccc attacgataa aattctcgcc
     8341 attcttctct tgccacacgg tagtagttca ttggatcatt catattagcc tcctgcgttc
     8401 tcccatcaat ggaactattt taacacaaaa taaacgcaaa ccccaccact taagagagat
     8461 tgccgatctt tttgtataat ctttataata gaaagaaacg gagtcttatt cttgacttgc
     8521 gcacggatac ataaaaggat agactgttgt catgaaagaa atgagaagga tggaagacat
     8581 gacaaatcat tactattctg aacgcccaga tacggcgcac gattttgaac aatgggcttt
     8641 tgagttaaaa ggcagaacct ttcaatttgt aacagattct ggtgtatttt cacgtgaaac
     8701 agtggattat ggttcacgtg tcctgattga tgctttcgat tgggaagagt tacctgatga
     8761 aggaaagatc ttagatgtgg gatgcgggta tggaccgatt gggttagctt tggcatttgc
     8821 gacacagcgg tttgttgaaa tggtcgacat taatgaacga gcggtaagtc tagcgcaagg
     8881 aaacgcaaag cgtaaccaaa tcgaacatgt tgatatccat caatcgaata tctatgaagc
     8941 agttcatgaa gaaacctatg cagctatcgt aagcaatccg ccgatccgtg ctggaaaaaa
     9001 agttgtacat gaaattttga caggcgcata tcctcggttg aagaagggcg gtacactgac
     9061 aattgtgatc cagaagaaac aaggagcgcc gagtgcgcaa aagaaaatgg aagaaacatt
     9121 tggtaatgca gaaatcgtca caaaagataa aggatattat atcatcaaaa gtgtgaaaga
     9181 ataactagct gaaaaatagt ggagcgacga aagagtggaa ctgggcgtgc atgtacgggt
     9241 acgtatcagt tctttttttg ttgagaagtt tttaaaaaca aagaactatt ttttcttcaa
     9301 aaagaaatag taggaacaga gtcgttgttt tttacgataa aataaataag atacagaact
     9361 tgtatagaag gctgccaagt cggtagataa aggaggtttt tatcaaaaaa catactttcc
     9421 ttttttctct attcttttct tgggggtttt ggtacactga tagggaattt agatagaagg
     9481 gagccaatag gatgaagctg accatcagag atatcgcaga aatggcaggc gtatcagtaa
     9541 caactgtctc acagattttg aataacaaag gaagcagatt tagtgataag acaagaaaaa
     9601 aagtgttgtc gatcgtgaat gaacatcatt ataagcccga ttatttcgct tcaaatgtga
     9661 tcaatcgaca ttcaaagacc atcggaatga tcgtccctga tgtcactgat ttcttcttct
     9721 ccaaactgat cgaaggtgta gagagctatt tgaatccttt gggctatgtg atcatgttat
     9781 gcaattctcg tcatagccaa gaaaatgaga tcaagtattt acaagagctt tcccaccgct
     9841 cagtggacgg aatcttgctg gccacaccaa atattttacc tgagaaatat gcattagaca
     9901 gcggttttta tcaaaaaatg ccaatcattt taatcgatcg cggattgaat cgtcgggata
     9961 acggacggct tatcgtaaag gaatatgagg gcgcctatca agctgtttcg ctgtttattg
    10021 aaaatggcca tacgaagatc ggcatgctga aggaaaccac tggatactat caattagaag
    10081 aacgtttcaa cggatatcgt catgcgctga aagatcatgg cctgcctttt aatgggaaat
    10141 ttgttgaaca tggagagttg actgtccaag gtggatatac tgcatcaaaa aaattactca
    10201 aacataaaga tatcacggct attttttgcg ggaatgatgc catggcgatc ggatgctatc
    10261 aggcgatcga tgaattgggc aaaaaaatcc cagaagatat ctcagtcata ggattcgatg
    10321 gattaaagct gtcagaatac atgattccgc aattgacgac agtgcagcag ccaagttttg
    10381 atattggatt ttatgctgca cgtttcctga tcgatacgat cgaatttcct caaagaaaag
    10441 ttccgaacaa agtgttcgaa acaaaattaa ttattcgtga gagcgtaaaa gtattgacaa
    10501 agggctaact cggcggtata ttgcttatgt aagcatttac aaaggctagt tagtgctttt
    10561 tttattttta gtaaaccagt ttactaaagt ggtttacctt tcctaaaaat aatgtataat
    10621 accgaatgaa gacaaggagg atcaggcaat gcgaatggtg gatctgattg aaaaaaagag
    10681 ggatggaaac gagctgtcga aagaggaaat cgagtacatc gtcacgaact atacgaatgg
    10741 aaagattcca gattatcaag tcagtgcatt attgatggca attttttatc aagacatgac
    10801 aaatgaagaa atcacgaact taacattggc gattgctaat tctggtgatg tcatcgattt
    10861 gagttctctt gaaggaataa aggtagataa gcattcgaca ggtggcgttg gtgacacgac
    10921 cacattgatt ttagcccccc tagtagctag tgtcggagtg acagtggcta aaatgtctgg
    10981 acgcggtcta ggttacacag gtggtacact agacaagcta gaagcaattc ccggatttca
    11041 gatcgagctt tcggatgaag aatttgtacg cattgttaat gaaagtaaag tagcggtaat
    11101 tggtcaatca ggaaacttgg caccggcgga caaaaaattg tatgccttgc gtgacgtcac
    11161 agcgaccgtt gattctcttc cgctgattgc cagttcgatt atgagtaaaa aaatcgcggc
    11221 aggagcagat gcaatcgttt tggatgtgac cactggagac ggtgctttca tgaagaacat
    11281 cgaagatgca agacgtctgg caaagaccat gacgagcatt gggaaactgg ctaaccgaga
    11341 aacagtggcg gttatctcag atatgtcaga acctcttggc gaagctatcg gaaatagtct
    11401 agaagttgtc gaggcaatcg aaacattaca aggaaatggt ccagaagatc tagtagaaat
    11461 gtgctacgcc ttaggaagcc aaatggttgt tcttgctggc aaagctaaga caaccgatga
    11521 agcaagaacg ttgcttcaag aagctctgga atcaggtaaa gcgttagcaa aattcaaaga
    11581 aatgatccaa aatcaagggg gagacccagc gatcgtggaa catccagaac gaattttgac
    11641 tgcacgctac acaatggagc ttcctgctaa acaaagcgga gttgtgtcaa aaatcgtggc
    11701 aaatgaatta ggaattgctg caatgatgct aggtgctggg cgtaaaacca aagaagaaga
    11761 tattgatcac gctgttggat tgaaactgca taaaaaaatt ggtgacactg tgacaaaagg
    11821 tgagtcacta ttgacgatct atagtaacga cgaagaaatc acttctgtca ttgaattatt
    11881 atataaaaat attgaaattg gtgaatcggc aatgaagcca acgttgattc atgacatcat
    11941 cacagaataa aggaaaaaag cggactttac cgttttaaag aaaaggggaa aagaaatgga
    12001 actaaaccga atgatcgacc atactatttt gaaagcagac gcatctaaag aagctgtgat
    12061 gcaaattatc gaagaagcaa aaaaatacca tttttattct gtctgcatca atccagcatg
    12121 ggttgcgcta gcgaaagaac aattacaagg tgagccagta gccgtatgta cagtaatcgg
    12181 gtttcctcta ggagcaaaca cacccgagac aaaagcattt gaaacaacag atgccatcaa
    12241 taacggtgca gatgaagtcg atatggtcat caatatcggt gctttgaaat caaaggatga
    12301 tcaacaagtc caaaaagata tcgaagcagt tgttgaagca gcaaaagatc gtgcgcttgt
    12361 caaagttatt attgaaacat cgttattaga tagagaagaa atcatccgag cttgcgaaat
    12421 agcaaaagct gcaggcgctg attttgtcaa aacatcaact ggtttctcaa caggcggagc
    12481 aaaggtagag gatgtccgtt tgatgcgtga aactgtagga ccagaaatgg gtgtcaaagc
    12541 ttccggcggt atccataacg aagaagaagc aatggcaatg atcgaagctg gtgctacaag
    12601 aatcggaaca agcgcaggag tagcaatcgt atctggttca actggtgaag gctattaatt
    12661 ttttcaaagg agaagctcat ggcagaactc aaacaagaat ggatcaacac agctattgaa
    12721 gcgttagata aagcctatgt tccttattcc cattttccgg taggcgcttg tctcgtaacg
    12781 gaatcaggca agatttatca aggcatcaac attgagaatg catcatttgg attaacgaat
    12841 tgtgccgagc gcacagcttt tttcaaagca gtatctgaag gagaaaaaac atttacgcat
    12901 ctagtcgtag cggggcacac ccccgatcct atctctcctt gtggtgcatg tcgacaagta
    12961 atggcagaat tctgttcccc tgatatgccg gttacgctag taggagacaa tggtgtgacg
    13021 aaggcaacga ccgttcgtgc actgctgcct tatgcattta ctgaaaaaga tctataactc
    13081 atgttcattc agtcagctga ctgttgaaaa ataaaacaat tattttagga ggctttacag
    13141 aaatgaaaaa agcaaaatta tttggtttag gtgctgtcgc actagcagca gggttatttt
    13201 taggtgcatg cggcaacaac ggctctactg attcatccgg tggcaaaagc tcatcagaca
    13261 caacaactgc agcattgatc acagacacag gtggtgtaga cgaccgttca ttcaaccagt
    13321 cagcttggga aggactagaa aaatggggga aagatcaagg actttcacga ggaaatgatg
    13381 gcttccaata tttccaatct tcaaatgaat cagattacat cccaaatatt gaccaagcat
    13441 tgaatgctgg attcaaaacg atttttggta ttggttataa actaaaacca gcgatccaag
    13501 aacaagcaac aaacaataca ggtacgaact ttgttattat cgatgatgtc atcgatggat
    13561 tagataacgt tgtatctgca actttcaaag acaacgaagc ttcttatctt gcaggtgttg
    13621 cagcagctta tacgactgaa acaaacgtag tcggctttat cggcggtgta aaaggtgaag
    13681 taatcgatcg ttttgatgct ggattcaaag ccggtgttga tgcaggtgcg aaagaattag
    13741 gaaaagaaat caaagtattg aatcaatatg ctggtgactt ctctgctcca gataaaggac
    13801 gttcaattgc tcaaggtatg tatgcacaaa acgcagatat catcttccat gcttcaggcg
    13861 gtacaggtaa cggtgtattc caagaagcaa aatcattgaa cgaatcaggc gacaaaaaag
    13921 tttgggttat cggtgttgac cgcgaccaat cagacgaagg cgaatacaca ttaaacggcg
    13981 aaaagaaaaa cttcacattg acatctacac tgaaagcagt tggaacagta gtagaagatt
    14041 tggcacaaaa atcagcggac ggtaaattcc ctggcggcga acacactgtt tatggattga
    14101 aagaagacgg tgttggtcta acagaaggac aactttctga cgaagcgaaa aaagcagttg
    14161 atgaagcaaa agaaaaaatc atttcaggtg acgtaaaagt tccagaaact cctgaagaaa
    14221 actaaaacca tttctatagc cttgttagac acatgtttga caaggctatg gtttgattag
    14281 aacaagaatt gttcatttat ccaagctgcc ttgtgacagt ttggataagg gaacaactcc
    14341 ctgaagtaat gtttgtttca aaagaagaac gctcactaag cgtgaatctt agtcaatcgt
    14401 tgccctagat agaaatcgtt aggatgtgaa aaaaaggtgg ttcaagaaaa tattgtcata
    14461 gaaatgcaga atattaccaa agaatttgga acattcaagg caaatgacaa catcaattta
    14521 caagtaaagg caggagaaat tcatgcgttg cttggagaaa acggtgctgg caaatctaca
    14581 ttgatgaacg tgctttccgg attattagag ccgacatcag ggaaaatttt gatgcgtggg
    14641 aaagaagtaa agatcacaag tccgaccaaa gccaaccaat tagggattgg gatggtccat
    14701 cagcacttta tgcttgttga tgcctttact gtaacagaaa acatcgtgtt gggaagcgag
    14761 cctagtcgcg cagggatgct tgaccataaa aaagcacgaa aagagatcca aaaagtttct
    14821 gaacagtatg gattgtcagt caacccagat gcttacgttc gtgatatttc agttggaatg
    14881 gaacaacggg tagaaatttt aaaaacactt taccgaggag cagatgtact gatttttgat
    14941 gagccgacag ctgtattgac ccctcaagaa attgatgaat taatcgtgat catgaaggaa
    15001 ttagtcaaag aaggcaagtc gatcattttg attacgcata agttagatga aatcaaagca
    15061 gtagctgacc gctgtacagt tatccgccgt ggaaaaggaa tcggtacagt caacgttaaa
    15121 gacgtaacct cacaacaatt agccgatatg atggttggaa gaacggtttc attcaaaacg
    15181 atgaaaaaag aagcgaagcc tcaagaagtc gttttgtcta ttgaaaatct agtggtgaaa
    15241 gaaaatcgtg gattagaagc cgtgaaaaac ttgaacttag aggttcgtgc tggcgaagta
    15301 cttggtatcg ctggaatcga tggaaacggg cagtcggagt tgatccaagc tttgactggt
    15361 ttgcgaaagg cagaaagcgg acatatcaag ctaaaagggg aagacatcac taataaaaaa
    15421 ccccgaaaaa tcactgaaca tggtgtagga cacgtgccag aagaccgtca taaatacggg
    15481 ttagtcctag atatgacatt atctgaaaat atcgcactac aaacctatca tcaaaaacct
    15541 tacagtaaaa acggcatgct gaattattca gtaatgaatg aacatgccag agaattgatc
    15601 gaagaatatg atgttcgaac aacgaatgaa cttgttcccg caaaagcttt atcaggcgga
    15661 aatcagcaaa aagcaattat cgctcgtgaa gtcgaccgag atcctgatct gttgattgtt
    15721 gcaaatccaa ctcgtggact ggatgtaggt gcgatcgaat ttattcataa acgtctgatc
    15781 gaacaaaggg acaaatacaa agcagtgtta ctgatcagtt tcgaattaga agaaatttta
    15841 aatgtttcgg atcgtattgc tgttatccat gaaggagaaa ttgtcggtat cgttgatccg
    15901 aaagaaacat ctgaaaatga attaggtcta ttgatggcgg gctatacctt agaagaagca
    15961 cgaaaagagt tagaaaaggg ggctggcgca catgaatgat cgcagcgaaa aattccgtaa
    16021 tttattagtg cctgtacttt cagttgtttt aggattgatc ttaggcgcga tattgatggc
    16081 tgcttttggt tttcagccca tccaaggtta ttcttctatg ctagatgcag cccttggttc
    16141 gcaaagaggg ataggtgaaa cgttaaggca agcaacgccg ttgattttta cagcattagg
    16201 tttttctgta gctaactcag ctgggttttt caatattggg ctttctggac aagcactttg
    16261 cgggtggatc gtcagtgtct gggtggcact tgcgtttcca gatctgccaa aagttgtttt
    16321 gcttccgtta tgcgtgatct taggtgcctt agctggtgcg atggcagcgg ctgttccagg
    16381 tttacttcga gcattttttg gaacaagtga agtgatcgta acaatcatga tgaactatat
    16441 cttattatac gtaagcacat ttgctttaca tgaagtgatg cctgaaagct atcgctcaag
    16501 tttggactct tccaatatga tcagtcaaaa tgcctcactg cggttaccat ggttaacaca
    16561 agcttttggc ggctctcgcg taaactcagg attattttta gcaatcatcg cgcttatttt
    16621 cgtttggctg ctgatgaaga aaacgacttt aggatttgaa atccgttctg ttggattgaa
    16681 tccttttgct tctgagtatg caggaatgag tagtaaacgt acgatcgttt tgtcgatggt
    16741 catttctggc gctttggcag ggcttggcgg tgtggttgaa ggattaggaa cgtatcaaaa
    16801 cttctttgtt caaacgactt cgctatctat tggatttgac ggaatggctg tttccttgct
    16861 tggttctgga tcagcaatcg gtattctttt atcagcgatc ttgttcagta ttttgaagat
    16921 cggtggactt ggcatgcaga caggagcagg tgttccgttt gagatcgtca atgtatcgat
    16981 tgctttgatt atcttctttg tcgggatcaa cttcctgatt cgtttcgtca tggctaaagt
    17041 cttccaaggg aaaaaacaag aagagatcgt tgcgacaata gaatcgaaac caacgaatca
    17101 aaaccatgaa gggggcgaac tataatgtcg actatcgaat taattgcctt gatccttact
    17161 tctacactgg tttattcaac accgctaatt ctaacgtcac taggcggaac tttttctgaa
    17221 cgaagcggga tcgtaaacgt agggctagag ggaatcatgg tcatgggtgc ttttagttcc
    17281 atcgttttca acttgacgat gagtccatca cttggttcta tgacaccatg gatcgctatt
    17341 ttagtgggtg gcgtcgtagg tatcctattt tctctgattc acgcagtagc aacagtcagt
    17401 ttgcgtgctg accatattat cagcgggaca gtaattaatc tgatggcacc tgctttaggt
    17461 gttttcttga tcaaagcatg gtatggtaaa ggtcaaactg ataacatcac gcagaatctg
    17521 gggtattttt ctttcccagg attagcagat attccggtca ttggaccaat tttctttaaa
    17581 aatacattct tacctgctta ttgtgctatt ttgattgctg tcctagcttg ggtgatcatc
    17641 ttcaagacga aattcggctt gcgcctccgt tcagttggtg aaaatcctca agctgccgac
    17701 acattaggta tcaatgtata tgctatgcgt tattcaggcg tactgatttc tggcttgtta
    17761 ggcggtatgg gcggtgctgt ttttgctcag tcgatttccg gtaacttttc agctggtacg
    17821 atcgttggac aagggttcat ctccatggct gctatgatct ttggtaagtg gaatccttta
    17881 ggggcaatgg gtgcctcatt gttctttggt tttgctcaaa gcttgagtat cattggcgca
    17941 caattaccag ttatttcttc gattccgcca gtattgctgc aaattgctcc atatttgctg
    18001 acaatcattg tgctggttgt tttcttaggg aaagcttctg gtccaaaagc aaacgggaag
    18061 aactatatca aatcaaaata atcttttagc gaataaaaag ggtgggttac gggaagtgtt
    18121 tttcgtctcg ccctttttgt tttaaaggca ataaaaataa aaagaaagaa ggaataatca
    18181 tgtttaaacg cgtacatctg atcgtcatgg attcagtagg aattggagaa gcaccagatg
    18241 ccgataagtt cggtgatgtt ggttctgata cattaggaca cattgcgaaa gaagcaggat
    18301 tgaacgttcc acatttagag cagcttggtt taggaacgat ccgtcctctt gaaggtgtgg
    18361 aatcagtgaa agatcatcaa ggctatgcga cgaaattaga agaagtttct gtagggaaag
    18421 atacgatgac aggccactgg gaaatcatgg gattgaatat caaaactcca tttcgtgtgt
    18481 ttcctaatgg attccctgat gatctgatca aacaaatcga agaattttct ggccgtaaag
    18541 tcgtatgtaa caaaccttat agcggaacag ctgttattga cgattacggt gaacaccaaa
    18601 tgaaaacagg cgatttaatt gtatatactt ctgccgatcc tgtccttcag atcgcggcac
    18661 atgaagaaat cattccttta gaagaattat atcggatttg ccaattcgtt cgtgatataa
    18721 caaaagatga tccgtatatg attggccgaa tcattgcacg tccgtacgtg ggtgaaccag
    18781 gagacttcac acgaacaagc aatcgccatg attatgcgtt gaatccattc ggacacacag
    18841 tccttgattc tttgaaagaa gcaggaaagg acgtgattgc tgttggaaag atcaacgata
    18901 ttttcaacgg acaaggaatc actgaatctg tccgcacgaa aagcaatatg gatggcgttg
    18961 accagctgct gaaagttatg aaaaacgatt tttcaggaat cagctttacc aatttagtag
    19021 attttgatgc attatacggt catcgtcggg atgtagtcgg ctatgcgcat gcgattgaag
    19081 aatttgactt acgaattcca gaattgcttg aagcgatgga agaagacgac ttgctaatga
    19141 ttacagccga tcacggaaac gatccgacgt ttactggtac cgatcatacg cgagaatatg
    19201 taccgttatt ggtttacagt aaaaaaatga aagaacaagg ggcattgcct caaggatatt
    19261 attcagatat ttcagcaacg attgctgaga actttagtgt ttcttcgact gaaaatggcg
    19321 aaagcttctt gaaattatta aaataatctt tttaaatagg agaaagcaaa tgaccaagtt
    19381 aagcgagatg ttacaagaaa cgacccagtt tatccttgat aaaggagtaa aagaaattga
    19441 ttttggtttg attctaggtt caggattagg tgaattagca gatgaaatcg aagatgctgt
    19501 aatgatttct tatgatgaga tcccgttctt tcctgtttcg acagtagttg ggcatgcagg
    19561 aaagctagtt tatgggtctc tggcaggcaa gaaagtgtta gccatgcaag ggagattcca
    19621 ctactatgaa ggtcattcca tgcaaacagt gacctatcca gtacgtgtga tggccggact
    19681 aggggcccat tcagtcattg tgactaatgc atgtggtggt gtcaacgaat catttgtacc
    19741 aggagatttg atgctgatta ccgatcatat caattttact ggtgaaaatc ctttgatcgg
    19801 tccgaatgaa gatgcaatgg gccctagatt tccagatatg agtcaagctt atacgcctga
    19861 ctatcaagca acagcaaaag cagcagcaga aaaactaggt ttggatctta aagaaggcgt
    19921 atatatgggc tattctggac caacttatga aacgcctgcg gagatccgaa tgtctcggac
    19981 aataggagcc gatgcagtag ggatgtcgac tgttccagaa gtcatcgtag cagctcacag
    20041 cggattaaaa gtgttaggaa tctcttgtat taccaactta gcagcaggta tgcaagcgaa
    20101 tctgagccat gaagaagttg tagaaacaac tcagagagtc aaacaatctt ttaaagcatt
    20161 ggttaaagaa acattgacat tattgtaata ggaggaacaa taaaatgagt gtgcatattg
    20221 aagcgaaaga aggcgagatc gccgataaga ttttacttcc gggagatcct ttgcgagcta
    20281 aatatattgc ggagactttt ttggaagatc cagtttgtta caatcaggta cgcggtatgt
    20341 taggctttac cggcaaatat aaaggagaac gtatttctgt tcaaggaaca ggaatgggaa
    20401 tgccatcagc caccatctat gcccatgaat tgatccagtc gtatggtgta aagaaattga
    20461 ttcgagtagg tacatgcggt gcattgtcaa aagacgtcca tgttcgtgat ttagtactag
    20521 cacaaggtgc agcgaccagt tcttcgatga tcgaaaaaaa tttccaagcc tttcattttc
    20581 ctccaatcag tgatttcaat ctattactga aagcatatga gatagctaaa gaaaagggct
    20641 atacggttca tgtaggaaat gttctttcgg aagattcttt ctacaaagat gatttgacag
    20701 agacgttcca attagctgaa cttggcgttt taggagtgga aatggaagca gcggctcttt
    20761 attacttagg cgcgaaatac catgtgcaga cattaagttt gatgaccgtt agcgaccatt
    20821 tgatcaccgg tgaagaaaca acagctgcag aacgtcaatc tacgttcaat gaaatgatcg
    20881 aagtaggatt ggaaacagcg atagcagaat aagaaggaaa tgaaaaagct gccctgcatt
    20941 aagtaataag aacatccaag caaaaatagc tcctcatgtt tttgacttgg ctggacttat
    21001 tattgcaaat gtaagctttt gaacaccgtt taccaagagg ttgtgaatct gccgtttaac
    21061 tctgagtcac aaggaacaat ttcaaaaa
//
LOCUS       DACBZK010000321        14784 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.guided.067, whole genome shotgun sequence.
ACCESSION   DACBZK010000321 DACBZK010000000
VERSION     DACBZK010000321.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14784
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.guided.067"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            366..1229
                     /locus_tag="IVD66_003117"
     CDS             366..1229
                     /locus_tag="IVD66_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP6147238.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            1329..1811
                     /locus_tag="IVD66_003118"
     CDS             1329..1811
                     /locus_tag="IVD66_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP6147239.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(2074..2541)
                     /locus_tag="IVD66_003119"
     CDS             complement(2074..2541)
                     /locus_tag="IVD66_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAP6147240.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            2664..3515
                     /locus_tag="IVD66_003120"
     CDS             2664..3515
                     /locus_tag="IVD66_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP6147241.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKALVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(3766..5724)
                     /locus_tag="IVD66_003121"
     CDS             complement(3766..5724)
                     /locus_tag="IVD66_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6147242.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(5721..6593)
                     /locus_tag="IVD66_003122"
     CDS             complement(5721..6593)
                     /locus_tag="IVD66_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6147243.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(6935..7807)
                     /locus_tag="IVD66_003123"
     CDS             complement(6935..7807)
                     /locus_tag="IVD66_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP6147244.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            7935..8504
                     /locus_tag="IVD66_003124"
     CDS             7935..8504
                     /locus_tag="IVD66_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAP6147245.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            8571..9308
                     /locus_tag="IVD66_003125"
     CDS             8571..9308
                     /locus_tag="IVD66_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP6147246.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            9539..10807
                     /locus_tag="IVD66_003126"
     CDS             9539..10807
                     /locus_tag="IVD66_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAP6147247.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            11294..11758
                     /locus_tag="IVD66_003127"
     CDS             11294..11758
                     /locus_tag="IVD66_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP6147248.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            11742..12371
                     /locus_tag="IVD66_003128"
     CDS             11742..12371
                     /locus_tag="IVD66_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAP6147249.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            12725..14203
                     /gene="msr"
                     /locus_tag="IVD66_003129"
     CDS             12725..14203
                     /gene="msr"
                     /locus_tag="IVD66_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAP6147250.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            14250..14696
                     /locus_tag="IVD66_003130"
     CDS             14250..14696
                     /locus_tag="IVD66_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAP6147251.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
BASE COUNT         4790 a         2642 c         3044 g         4308 t
ORIGIN      
        1 gatgaggttg aacttttaca caagattgtg gacttgactg caaagaaaaa tccaagcagc
       61 gttctgatca gcagtttgaa caacaatttg ctttgtacag taggtagtaa gcggattaac
      121 taagggaata aaagatattt ttaccgcttt gtttacttag aatctgtctt ccccaaaatt
      181 tatttttcta aaggtaaaac atagataggc agataatacc aattatccgt tacgaaacgc
      241 tgcttgagaa ttttctttag atccatacaa cattttctac atctgactaa attggttcct
      301 gattcatcaa gtaattgact ttctttgata atatgataaa aaggcaatca aggaggaaga
      361 taaatatgct taaagatctg aaccaattga tcgattacat cgaagaacat ttgacagaag
      421 gactttccta taaaataata gccgaaaata caggaatctc tgaatatcaa ttaaaacgca
      481 tctttacgtt tattgcaggg atgtcgctaa tggactatat caaaaaccgt agattggctt
      541 tggctaatcg cgatcttcta gatggatcaa gagtgacaga aacggcgttt agatatggat
      601 atgaaacagt cgaaggtttt tcaagagctt ttcgtgattg gtcaggatat ctgccttcag
      661 aaatcagcag atacggcata caaaaatctt ttccacgctt gacatttttt attgatgtca
      721 gaggaggaaa atcgatggaa tttcgtatcg aaaagaaaga acagttttat gtggcaggtg
      781 tggcgaaaaa agttcctgtc aaatttgaag gagtcaatca agaaatacaa aagttagcgc
      841 agacgatcac ggagactcaa agggaagaga tgcataagtt aggagattta tatccaaatc
      901 aagtaatcaa cgtttcttat ggatttgatg gagaccgctt ggaagaaaag ggcagtttga
      961 tgcacatgat tggctttgct acgacaaaag aaaatccgta cgctgattta gaaatgcttg
     1021 ctatagaaga acacacttgg gccatttttc ctaataaagg gccatttccc caaactttac
     1081 aagatacttg ggggaaaatc tatgcagaat ggcttccttc ttcagattat gggttagtcg
     1141 aagctcccga gatctctttt acaaaatggg gagaggattt cagtaatgtt tacagtgaga
     1201 tttggattgc agtgaaagca aaaaaatagt taaaaaataa aaatatccct agaaaaaaga
     1261 gcgtaatcgt gtcatttccc tttaatttta tgtaagatga acttaatata atagaaaggg
     1321 tgggagaaat ggcaaagtat aggatcgaag aaaaaccaga ttttacggtg acgggtattg
     1381 gtgtggaatt gaagagtagc aatacggatt ttgtcggttt ggctgcagag aaacaagcat
     1441 ttgagcaaaa agttatcggt aatggaacaa tagatgcatt gaaacaagct gctgaaaatc
     1501 attatttctt tacagtcaac gaaccctata acgggaaaat gatgtactat gtcggtgttc
     1561 aaacgagtca ggatgttcca aacactacgc gaatcatccc attcccaaaa ggaacgtatc
     1621 ttgttgtaag cgctttagca gaatcgcctg aagaattaag aaatgatttg acgaatacgg
     1681 cctttgggca tgttttaaga gaagtagaag attacgccta tgttgggggt ccaaatgctg
     1741 tagtcgaaat gggagttacc aacgggaaat atatgggaga aatctggata ccggtagtca
     1801 ataaaccatg ataatataga ggtcgtgaaa gtagcgcttt gacctgagca ttagagagga
     1861 aaaatgggaa atagctttcc atattttgca tttttcagaa ctaatgccga gggtcagcta
     1921 cttgaacacc gtttatcaag acgtcatgac ttcagcgctt tgacctgagc attagagagg
     1981 aaaaaggggc atgacaaggc ttttgtcccc cggagaataa aagaatttat gtagacgatt
     2041 ccgatcagaa aaatgcaggc acagtagaga gaattataaa aatctctcta cgaggcctgt
     2101 gttttctggt cttttttctt tttccaaaac ggctatttta tgtatcagac tatcaagtgt
     2161 gatcttagcc atttcttctt ctgccttttt ctgcagccga gcgtagcttt cttctaaagc
     2221 ttcttggata ttcgcaccaa cgacgcaatt tggatttgtt tttggatcga cttggataag
     2281 ctgtgtatta ccttcgatgc tgcgatagac atctagtaaa gaaatctgat ctggactttt
     2341 ggcaagggaa ggctgcggtt ttccggtttt tgtaaagatc aaaccggatt ttttgagctg
     2401 actcatgatt ttacgtacat ttgctgcatt tgtttcgata ctactggcaa tcatctcact
     2461 agaaagtgat cgggtatctt gaaacatttc aatataggca agtacatgga ttgcatcact
     2521 aaattgcaga gaatacttca tcagttgtca tcctttcatt ttttttgctt gacttatctt
     2581 accacactct ttatgataaa ggtgtaattt ataaatgtac agctgtaaat cttaacaaat
     2641 aaaaagaata gggagtggca aatatgcatt atttagtaac aggagcaact ggaggttttg
     2701 gtggttatgc gctggaattc ttaaaaaaga tggttccaca aaatgaaatc tatgtactag
     2761 tacgtagtga agaaaaagga gaagcactga aagaagctgg atttaatata cgtattggtg
     2821 attatgatga tttagactca atgaaagaag cgttgaaagg aatagatcga ttgctttttg
     2881 tctctggcgt tccaggaaat cgtcaagccg aacataagaa tgtagtgaag gcagcacaag
     2941 cagctggggt atcttatatc gcttatacaa gttttgcaga tgccgatcac tcgatcagtg
     3001 tattagcgcc agatcaccaa ttcactgaaa aaatgattaa ggattcaggt atttcccata
     3061 catttttacg gaataattgg tatgtagaga atgaattacc tatcattggg caggctttaa
     3121 aaactggtca attcgtttat gctgcaggaa atggaaaaac aggttgggca ttgaaacgtg
     3181 aatatgcaga agctgcagca aaagcactag tagaaagtga ctctccagaa atcttagaat
     3241 tatccggcaa tctaactgac tatgaagaat tagccaaggc attagagcgt gcgacaggta
     3301 aagagttaga aattattgaa gcaagtgatg cagcgtttgt cgaaaatcta aaagaagccg
     3361 gattccctca agaagcagct gacatgtttt tagcgatcca acatgatatt aaaaaggatc
     3421 agttagctat ttcctctgat gatttagaaa aagtattggg aaaaccatta acttctcttg
     3481 aagcagcatt aaaagaaata ttggatcagg aataatgtat aaagaggttg tgaaaaagcc
     3541 gattagtttt gagtatgaag aaaaattttg tgaaaaagct gttctgcatc aagtaataag
     3601 aagagtcaaa taaaaaatag ctcttcatat gtttcgttta gctggactta ttaccgcgga
     3661 gttggcagga gaacgccgtt tttattcgga aaaaggagct gagacaagat ttttgtctca
     3721 gctcctgttt gtttatcgat aaaaaagtct ggggaagacg atggctcagg ctttgttgga
     3781 aacagagccg attttatcat ttgcttttac atcacgtgcg ggttcgattt ctaagctttg
     3841 gactttgtcg ccatttgtga atacaacgac catatccgtg tttttgcctg cagattgaat
     3901 agcggcaaga tcaactaaag caatcaattg acctcttgcg actttttgac cttcttctac
     3961 atataaagtg aatggttcgc cttttaagtc aacagtgttg atgcccatat gaagcaagac
     4021 ttcgatacca gcatctgttt ggattccgac agcatgtttc gttgggaaaa tgtttgtgat
     4081 cgtaccagcg attggagaga agatttctcc attttctggt aatacagcat agccgtcacc
     4141 catcattttt tccgcgaata catcatctga aacttcagtg attggaatca gtttcccatt
     4201 tgcgatagcg taaatatctt gttcgatcgt ttcaccggca aatgtttctg ttttaaccac
     4261 ggtgtttgtt tgtgcaggtc gtgctgcagc accaccatgt agttttgcca tctcatctgc
     4321 aacgaattgt acttctgtac ctacgatgac ttgcgcattt tttccgtcga tgatcttcat
     4381 accaggtacg ccagtggctt tgattttatt ttgatcgatc aggcctgtat ctttgacttg
     4441 caaacgaagg cgtgtagtac agttatcgat cgaagttaca ttgtcggctc cgcctaatgc
     4501 agcgtagatt ttgcttgctt gtgccgcata tttattgtct gaattagtcg ttgcagtatc
     4561 gtcatctgaa agatctgctt cctcgcggcc aggagtcatc agatggaatt ttttgatagc
     4621 aaagttaaag ccaaagtagt aaatcactgc tgttactaat ccttggacga tcaacatcaa
     4681 tggctgattc gcaatcggat ttttcaaaga taggaagtaa tcgacaaatc cggcactaaa
     4741 ggcaaatcct gctgtccaat ggaagaatgc actcactgct aaagaaatcc cagtgaaaat
     4801 tgcatgcaag acatataatg gccaagcaac gaacataaat gaaaattcaa gtggttctgt
     4861 cacaccagta aagaatgaag caaaagctgc tgctagcatc aaggaagctg tttttgcttt
     4921 gttttctgga cgtgcatttc tgtaaatagc atatgctcct gctggaagcc cgaacatcat
     4981 gattgggaaa aatccagctt gatacattcc tgttacgcct tttgttcctt cagaagccaa
     5041 aaatttacca atatcattga ttcctgctac gtcaaaccag aacacggagt tcattgcttg
     5101 atgcaatcct gtagggatca gtaaacggtt gaagaagcca taaagacctg caccacccca
     5161 gcctaaactc aaaatgaatt tagcaaaaga aactaaagca gagtaaaccg gaggccatac
     5221 gagcagtagc actgcactga tcagcaacat gacaaaggca gccaagattg gcactagacg
     5281 cttgccgcta aagaaagata aagccatcgg taattttgct tcgtggaaac gattataaag
     5341 agctgccgca atcaatccgg caataatacc aataaatacg ttactgatct gagcaaaaga
     5401 tggatcaact gattctggtt tgatattcaa taaagtagct actgaatcag tttttaaaac
     5461 atttactgga acttcaaatg cgaccaaacc tgccaaggca gcagcacctg atttgtccac
     5521 tgacatccct agtgctaacc caacggcaaa cagcaaaggt aattgaccta aaactgcgtt
     5581 accgccagct tgtaaaaaat gagcgacaat gtcgttacta taagatgccc accagtttcc
     5641 gatccctact agtaaagcag cagcaggtaa gaccgcaact ggaagttgaa gggaacgtcc
     5701 cattcgttgt agatatgctt tcaatttttt tcctcctcat gattgttaac atttgtttgt
     5761 acgattgcgc ttcttaaacg ctcgatatgg atggccaagt aacccagttc ttctttcgtg
     5821 atcgcgagct ggtattcttt ggtcagcaac acacggattt ttttagaaat cttatagctt
     5881 tctgggtatt ttcgtttgac catttctacg atttccgtgt ctaaaacagc atattgttgc
     5941 gcatgggttc gttgtagaag tagtcgtaaa tgattcacca gtcttgaata attcagtgaa
     6001 aatggttctg aatggatatc tgtttccaat tctgattcca ctaaatggat gatgtcagat
     6061 acaatcgtca cttcacggat actgcgatgg ttattgttcc gaccgcttcg tccgctgtga
     6121 atatggattg cgatatatcc tgcttcgtca taagtatatg gaatcccaag ctcttttgtc
     6181 agatactcta ctgcccattg agcaatactg aattcatcac tgtaaagcac ttcgatttct
     6241 cttaaaagtt tgttgcggat gacgataccg ttattaatgt tctccgcaga aaaagcaatg
     6301 tggtcggtca aagcgatcaa tacatgttca ttcaactttt ccatcaaaac agtttccgca
     6361 tgatcaatga tcgtttctgc tgcaaataaa aagcgttcat caatctgatt aagtaaattt
     6421 tgcaacttga tttgaccttc tggttccatg acaaatatcc gttcgacatc acgatcaaaa
     6481 atcaaatcat ttctttttct gtcaaatcca atcccttttc caatagctac tttttcctgt
     6541 ccaccgtcat ctaccaatac tgcattttga ttaaagatct ttttgatttt catgcgcgca
     6601 ccctttttga agatttggtt ttcacgtttg ctagaccagt tgattgcggc caaacaaaaa
     6661 tagacacgaa aaacctccta gggaaaccat gttcctcaga gatttttcat gcctagtatg
     6721 atctagtcac atgaaacgaa ttattgttaa cgtaatcaat tttatataga cagttatgtt
     6781 ttgtcaattc tttttttata attatagtaa tttactggaa ttatcagaaa taaaaggaag
     6841 aaataaatta agaaacttat gttatttaat cgttggatct tttgcttatc ttattcgttg
     6901 ttaaaaagct gaaagcgaag gaaaaaaact ctacttaact gtatttctcc gttaggacat
     6961 ctaaaaattt acgagcagca ggagaaagag gctggtcttt tttccaaatg agattcagtg
     7021 aagcttgtaa tggcggatcg agtgggatga atattttttc cgtcccataa gtattgatga
     7081 tcccatctag agctaatgca ccaaaagtcc cgttatcgac catcaaagaa gcattgtaca
     7141 ataagttata tgttccgacg atcgataact gatctatgct gaaacctagc cattcagcta
     7201 gttgactgtc cactgacgtt tgccgggaaa tgatcaaagg aacagttttc agttcctgcg
     7261 gatggatgac ggtttgcttt gctaaaggat gatttcgatg tatcaaaagt ccccaacgat
     7321 cttgggctgg cagtcgaaat gactggtatt tttgtttgtt tgtcggttcg attacgagtc
     7381 caaaatcaag taatccgcta tccagtttgt ctatgatatc atctgcattc ccgctatata
     7441 aatgaaactg gatatcagga tgcgccttga tcaacgaatg aaggctatca gaaatgaaag
     7501 agattgcttt agtttcgcct ccgccaatgt agatttctcc agagatgatt gcgtcatttg
     7561 ttaaattgtt cgccgttttt tctaccaacg acaagatttc ttttcctttt gaataaagat
     7621 atcgaccaga atccgtcaac tgtatctctc gggagccccg agtgaaaagt gtcacaccaa
     7681 gttcttcttc taaatctttc agttgttttg agagagtagg ttgcgtgata tgcagagatt
     7741 ttgctgctcg gctgatattt ttttctctag ctactgctaa aaaatacgtc agtatacgaa
     7801 tatccatttt ttccctcctg tttttaaaaa agcataccac taagtatagt taaaaggaat
     7861 agttaagtat gttttataag tattagacat gataagccgt ccgttataaa gtaaggataa
     7921 aaggagggag caaaatgaca agcctcatcg aaaaacaaat cgtcaataaa gagattcgag
     7981 taacggatcc gctctttgaa gtgatccatc agatccaagc tgaaaacgaa gagcctttag
     8041 cagcgctgaa tactgggtac catgaaccag cagatatccg caaacggcta gaaaatatca
     8101 ttagtgacaa agtagatgat acggtgactg ttctgctgcc tttttataca gatttcggca
     8161 aacatattag tatagggaaa aatgtcttta tcaatcgtca agtgatgttc gttgacttag
     8221 gtggcatctg tttagaagat tcagtattga ttggtcctcg tgtcaacctc atcacggtga
     8281 accatctaac cgatccaaaa gaacgaagag gcttgtcagt aaagccaatc cacatcaaga
     8341 aaaatgcttg gatcggagca ggagcaacta ttctgccagg cgtaacgatt ggcgagaatg
     8401 ccattgttgc agcgaatgca actgttacga aagatgtccc agacaatacc atcgttgcag
     8461 gaatccctgc caaaatcgtc aaacctgtcg aacggattat ttgaacagta agatgaaata
     8521 agagatagtg agtataagca agagattttt caaaacagga ggagaataga atgaatgatt
     8581 tatcagaaaa agtgattgtc atcatgggcg cttcaagcgg aatcggtgaa gcaacaacga
     8641 agctattagc agaaaaaggg gctaaactag ttatagctgc acgccgagaa gatcgcctaa
     8701 aagcaataaa agaatcttta ccagaagctg agctatatat tcaaacagca gatgtaagag
     8761 attttgcaca agtccaagca gttatcgatt tagcgatgga aaagttcggt cgaatcgatg
     8821 tattgtacaa taatgcagga atcatgccaa ccgctccatt agttgaaggt caccgtgatg
     8881 aatggcaaaa tatgcttgat atcaacatca tgggtgtgtt aaatggaatt tccgccgtac
     8941 ttccaatcat ggaaaaacaa aaatctgggc atatcatttc aactgattct gtggcgggac
     9001 atgttgttta tcctgattcc gccgtttatt gcggaacaaa atttgctgtc cgtgcaatca
     9061 tggaaggatt acgtcaagag caacggcaaa ataacatcaa atctacgatc atctctccag
     9121 gagctgttca aactgaatta tatcaaacca tcagcgacaa aaaggctgct cttgaacttc
     9181 atgaagcgca aaaagaatgg ggattgacct ccgaagatat agcttctgct gtagcatttg
     9241 cgatagaaac gccagaccgg atgtctgtca gtaacatgat tatccgtccg acgacacagg
     9301 aagtataatc cataacggat aatatccaaa gagaattact tgttaaatag ttattcaaac
     9361 gaccatcaat ttaaggcgtg aatggagaag aatattcttc atttacgtct ttttatgtag
     9421 aaaaagcaaa ttcatcaaaa agaaacaaat gttatttaaa tatggacatt gacttgcttt
     9481 tactttttta gttacactgt tatttaggaa aagtttcata attcaaagga gaaaaaagat
     9541 gaaagcaaag aatttattat ttagcgttat tcttttagga aatctagcag ttgccaacac
     9601 aacagtgcta gctgaagaat cgacagaaac tgtcgcaact cagacatcga gttcttcaga
     9661 aacaggaatt gaaaacgata cagagagtac tttgcagtca gctactgtct cagaaaatac
     9721 aatttcaacc gaagaaccaa caactgaaac aacagaacaa acacaaaccg aagacagtac
     9781 atcagcagaa gctcagaaca atccagagaa tgcagaagaa atcacgaacc aattgacaga
     9841 tgggcaaaca ttgacacata cccatcaagc agatttgtct gaattcgaaa actatactgg
     9901 ctatgctttt tatgctcgct catctgctaa ttctcaacaa gcgttcattg atagtattgc
     9961 ctcaactgca caaagtttgg caagtgccaa tgacttatat gcatcagtca tgattgctca
    10021 agccatcgtt gaaagtggct gggggaacag tactttggct tctgccccta attacaatct
    10081 atttgggatt aaaggaagct ataatggcca atctgttacg atgcctactt cggaatatgt
    10141 gaatgggcaa tggattacgg tgaatgccgc ttttagaaaa tatccttcgt acaaagaatc
    10201 attgcaagat aacgtaacgg tattgaagac gacttctttt cagccaggcg tttactacta
    10261 ttccggtgca tggaaaagca atacgaactc ttacaaagat gctacggctt ggctaacagg
    10321 tcgttatgcc actgcgccta attatggttc tacattgaac aatgtaatcg aaacctataa
    10381 tctgacacag tatgatacag caccaacttc aacttctccg atgtatcgtc tgtataaccg
    10441 tcatacagga gaacatttat atacattgaa tgccggagaa aaaaattatc tgccaactgt
    10501 aggctgggaa tatgaaggga ttgcttggca agcaccaaac agcggacaac ctgtctaccg
    10561 tttatacaat ccttacagtg gagaccatca ttacacaatg gcacaatctg agatcaactc
    10621 tttaacaaaa atcggttggc gttatgaagg tctaagtttt tattctggtg gttccaagcc
    10681 aatttatcga ctatttaatc caaatgaaaa aactggtacc catcactata ccttgagtgc
    10741 taaggaaaga gattggctaa caccgatggg ctggagatat gaaggaatag gattttatgg
    10801 ttattaaaaa gaggtagtga aaaagctgcc ctgcatcaag tagtaagaac agccaaacaa
    10861 aaacagattt tcatgttttt tgtttggttg aacttattac cgcagatgca agtttttgaa
    10921 caccgtttac tcaaaaaagg ttgtgacaac atcttgtcat aactttttta ttactgttta
    10981 agcatactga tccaatttct aatattcgac gggattcttg caaaaggcga tttcggaaat
    11041 ttttggcggt gtaaaatttt ctactgcaga agagctatct tctatagttt gataagaatc
    11101 aataatcttg gttttagcgt tgtgctttct ttatcatttt ttccgttcat tctacaaaaa
    11161 atttcttttc tctatacttt tctattgaga gcgttttttt tattacacag ctgattcttt
    11221 gacttttttc tttttttatt ctattattga caagtcaatc gttgacgagt caattattag
    11281 aaaggaggaa attatgtctt tagaagagat tagtcacctt ttatatcaaa tcaaattagc
    11341 cgatcaaaaa atcgtccaga tctttgaaga aaatatcggt ataagtctta ctagatacga
    11401 gatcatgatg agactgaaag aagaaaatcc attgctacaa agcagtttgc aagaaaagtt
    11461 gcagattgat caaggagcag ttactcgtca tctgaaggta ttggaagcaa atggctatgt
    11521 ttcgcgtcag agaaatcctc agaacaaccg ggaagtgtat gtagcgctaa cagaaaaagc
    11581 ccagaagaaa atcgagcatt gtgaaatgga ccataaagat acaggttccg tgctatcccc
    11641 ggctttcagc gatgtagaaa tgaaacaatt tctaacactt ttagataaat tgaataccca
    11701 actttgcaat ataacaacag aaacgaaaga ggttaataat aatggaacaa aaaaatgatt
    11761 tttcaacaat tatgactggt agaagatccg ttcgcgtata tgatgaaaca tacaaaatcc
    11821 cacacgaaga aatgctggaa atgatcaaag aagcgacgac tgcaccttct tctgtcaata
    11881 tgcaaccatg gcgctttgtg gtcgctgaaa gcgaggaagc aaaagaaatc ttgcgtcctt
    11941 tgatccgttt caatacgaga caaaatgata cttcttctgc aatggtcatg atttttggcg
    12001 atatgcaatg ttacgaatat ggcgaagaaa tctataacca agcttacgaa tcagggaaga
    12061 tgccaaaaga agtcagagat caacaattag ctgcgatcat tccttattac aagagttttt
    12121 caagagaaga aatgaacgat gtagtcaaag tcgattctag cttagcggct atgcaattca
    12181 tgttagttgc gcgtgatcat ggctatgaaa caaatccaat tggtggattc gaagcagatc
    12241 agttggcaga ggcatttggt ttggataaag accgttatgt tccagttatt attttatcaa
    12301 taggaaaagc ggtagaagaa ggttacgagt ctgttcgttt agcaccagaa aagatcacta
    12361 cgttcgaata aaaggttttc agttactatt cagtagctat tgcttttttt gaatcgtgtg
    12421 tggtaaccta ataaaaaagg aggtcggaaa aatgactgca tcgatgaaat tacgtttcga
    12481 acttttgaat aacaactaaa taaattcaaa agacatgtat aaacaacaat ttcatggatg
    12541 gagtatgtcc attttttcga acgacagtag aataggtgaa agctatgaca gatttggtga
    12601 tttagtcata gttatttcgt tcagagtagg aaaagatgtg atgcagtttt tttgcaaaca
    12661 gatttttctg ctctttttta gtatcgataa ttgttgtttt acatgaaata ggagtgtaaa
    12721 acatatggaa aatttagcag taaatataac aaatctacaa gtcagctttg gcaaccagct
    12781 agaactatct attgattctc ttcgtgtcta tcagcaagat cgtataggga tcataggaga
    12841 aaatggtgtc ggtaaatcga ctttgctcaa actaatagcc ggtgaacttt ttcccgatca
    12901 tgggaaaatc caaacagaga tcaccttcaa ctacctgcct caattaacct atctcgctga
    12961 agcaaaggac ctaaatttgg aattagccag tcatttccag ttaagactgg aagaaacttc
    13021 agagcggaaa tggagcggag gggaagaacg aaagatcgag ttgatacgtc ttctttcttc
    13081 ttatgaacaa gggatgcttc tagacgagcc aacaacccat ctagatagaa aaagtattga
    13141 tcgactgatt gaagagcttc gttattatta tggtacgctg gtttttgtta gtcatgatcg
    13201 ctattttcta gatgagctag catcgaaaat ctgggaagta aaagacggag aaatccgaga
    13261 gttttcgggg aattatagtg cctatctcac tcaaaaggaa ttggagaaaa agactcagct
    13321 acgagaagca gagtcgatca tgaaagagaa aaaacgattg gaaaaatcga tccaagaaaa
    13381 gaaaaaacaa gcggaaaagt tggaaaaagt gtccagtaaa aagaaaaagc aacaaatcag
    13441 accggatcgg ttgtcttcct ctaaacaaaa agacagtgta caaaaagcca tccaaaagaa
    13501 tgcgaaaaca ttagagagaa gactccaaaa aataggagaa acaaccaagc cgcagcagat
    13561 gaaacaaatc cgttttccag taccaaaatc tcttgaactc cacagccgct atcccatcat
    13621 gggacaaaat gtccaattgg aaagaagtgg gagaacatta ctggtaaatg gtgattttca
    13681 gttttcttta ggtaaaaaaa tcgcgattgt cggtgaaaat ggttcaggta agacaacctt
    13741 attagaacat atccgcaaac aaggagaagg aatccttctc tctccgaaag taagctttca
    13801 agtatatcag caaaagggtt atcaaatgac atctgaagaa tccatcattc gttttgtcat
    13861 gagacaaaca gagttttcag aatcgcttgt ccgtagtttg ctgaatcact tagggtttgc
    13921 tcaggaaact ttgacgaaac cgttatgtac attaagtggg ggagaagcga cccgtctgac
    13981 gattgctttg ctttttacta agccaagtaa tgtgttgctg ttagatgaac cgactaattt
    14041 tattgatatg gcaacgatcg aagctttaga gaagctaatg caaatatatc cgggaacgat
    14101 tttgtttact tctcatgatt cttactttgt cgagcgtacg gctgatgaag tttatgaaat
    14161 aaaagggcag aaaataaaaa aagtacttac gagaaatttt taaatgtgct acgatgattt
    14221 tcgtgacaaa tttaaaggag tggtacagat tgcctacaaa taaaaaagaa ggaataattt
    14281 ttacaacaat gatgtgtttt ttgatggtct tggggatgag cgcgtataat ttatggctgc
    14341 atcaagatct tcatttatca agtttgttga ttggtctagt gcctggattc gtggtggctt
    14401 tcattttgga tgtcttcatc atcggtgtgc tggcgaaaaa aattgccttt aaactaccag
    14461 taaatccaga aagcaaggtc caaatgatct taactatttc atgcttgatg gttttaggaa
    14521 tggtgacatg tatgtcttta ttcggtgtga tcatggaaca aggaatacct gatcaattat
    14581 tctctgctta tatgaatgct tggaaaatga atgtgattgc cgctttaccg ttgcagttga
    14641 tcatcgttgg cccgctttca agaagtgtgc taaaagcaat tcaaagtaat gaatgatgga
    14701 acactgttat ttgaaaaaag gccttggcat gctttttgtc atagtctctt gaatgcagtt
    14761 ctagaaaaat agtgatccga acga
//
LOCUS       DACBZK010000322         8769 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.guided.090, whole genome shotgun sequence.
ACCESSION   DACBZK010000322 DACBZK010000000
VERSION     DACBZK010000322.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.guided.090"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            complement(134..577)
                     /locus_tag="IVD66_003131"
     CDS             complement(134..577)
                     /locus_tag="IVD66_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAP6147252.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="IVD66_003132"
     CDS             complement(795..2135)
                     /locus_tag="IVD66_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6147253.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="IVD66_003133"
     CDS             2404..3300
                     /locus_tag="IVD66_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAP6147254.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="IVD66_003134"
     CDS             complement(3450..4391)
                     /locus_tag="IVD66_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAP6147255.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="IVD66_003135"
     CDS             4517..5638
                     /locus_tag="IVD66_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP6147256.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /locus_tag="IVD66_003136"
     CDS             5896..7398
                     /locus_tag="IVD66_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAP6147257.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7465..7992
                     /locus_tag="IVD66_003137"
     CDS             7465..7992
                     /locus_tag="IVD66_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP6147258.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            8203..>8769
                     /locus_tag="IVD66_003138"
     CDS             8203..>8769
                     /locus_tag="IVD66_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAP6147259.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGL"
BASE COUNT         2922 a         1614 c         1741 g         2492 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattg
//
LOCUS       DACBZK010000323         6682 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.guided.104, whole genome shotgun sequence.
ACCESSION   DACBZK010000323 DACBZK010000000
VERSION     DACBZK010000323.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.guided.104"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            109..192
                     /locus_tag="IVD66_003139"
     CDS             109..192
                     /locus_tag="IVD66_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HAP6147260.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            317..1054
                     /gene="erm(B)"
                     /locus_tag="IVD66_003140"
     CDS             317..1054
                     /gene="erm(B)"
                     /locus_tag="IVD66_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAP6147261.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1224..1484
                     /locus_tag="IVD66_003141"
                     /pseudo
     CDS             1224..1484
                     /locus_tag="IVD66_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase"
     gene            1647..2312
                     /locus_tag="IVD66_003142"
                     /pseudo
     CDS             1647..2312
                     /locus_tag="IVD66_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284571.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2348..2593
                     /locus_tag="IVD66_003143"
     CDS             2348..2593
                     /locus_tag="IVD66_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP6147262.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2696..3565
                     /locus_tag="IVD66_003144"
     CDS             2696..3565
                     /locus_tag="IVD66_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAP6147263.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3546..4280
                     /locus_tag="IVD66_003145"
     CDS             3546..4280
                     /locus_tag="IVD66_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP6147264.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4313..5228
                     /gene="ant(6)"
                     /locus_tag="IVD66_003146"
                     /pseudo
     CDS             4313..5228
                     /gene="ant(6)"
                     /locus_tag="IVD66_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
     gene            5225..5767
                     /gene="sat4"
                     /locus_tag="IVD66_003147"
     CDS             5225..5767
                     /gene="sat4"
                     /locus_tag="IVD66_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HAP6147265.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5860..6654
                     /locus_tag="IVD66_003148"
                     /note="aph(3')-IIIa"
     CDS             5860..6654
                     /locus_tag="IVD66_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAP6147266.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT         2345 a         1004 c         1396 g         1937 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccatt ttgtgtataa taggaattga
       61 agttaaatta gatgctaaaa atttgtaatt aagaaggagg gattcgtcat gttggtattc
      121 caaatgcgta atgtagataa aacatctact gttttgaaac agactaaaaa cagtgattac
      181 gcagataaat aaatacgtta gattaattcc taccagtgac taatcttatg actttttaaa
      241 cagataacta aaattacaaa caaatcgttt aacttctgta tttatttaca gatgtaataa
      301 cttcaggagt gattacatga acaaaaatat aaaatattct caaaactttt taacgagtga
      361 aaaagtactc aaccaaataa taaaacaatt gaatttaaaa gaaaccgata ccgtttacga
      421 aattggaaca ggtaaagggc atttaacgac gaaactggct aaaataagta aacaggtaac
      481 gtctattgaa ttagacagtc atctattcaa cttatcgtca gaaaaattaa aactgaacat
      541 tcgtgtcact ttaattcacc aagatattct acagtttcaa ttccctaaca aacagaggta
      601 taaaattgtt gggagtattc cttaccattt aagcacacaa attattaaaa aagtggtttt
      661 tgaaagccat gcgtctgaca tctatctgat tgttgaagaa ggattctaca agcgtacctt
      721 ggatattcac cgaacactag ggttgctctt gcacactcaa gtctcgattc agcaattgct
      781 taagctgcca gcggaatgct ttcatcctaa accaaaagta aacagtgtct taataaaact
      841 tacccgccat accacagatg ttccagataa atattggaag ctatatacgt actttgtttc
      901 aaaatgggtc aatcgagaat atcgtcaact gtttactaaa aatcagtttc atcaagcaat
      961 gaaacacgcc aaagtaaaca atttaagtac cgttacttat gagcaagtat tgtctatttt
     1021 taatagttat ctattattta acgggaggaa ataattctat gagtcgcttt tttaaatttg
     1081 gaaagttaca cgttactaaa gggaatggag ataaattatt agatatacta ctgacagctt
     1141 ccaagaagct aaagaggtcc ctagcgccta cggggaattt gtatcgataa ggggtacaaa
     1201 ttcccactaa gcgctcggga ccccttgtag gaaaatgtcc taagtgtggc aacaatattg
     1261 tattaaaaaa atcgttttat ggttgttcaa attatcctga atgtaagttt actttagctg
     1321 aacattttag aaagaaaaaa ctaaccaaaa cgaatgtaaa agaattactg gagggaaaag
     1381 aaaccctggt aaaaggaatc aaaaacaaag agaaaaagcc ctacaatgcc gttgtaaaaa
     1441 ttggggaaaa gggatatatt gattttatct ctttttcaaa ataaacatgg ggctgaccca
     1501 aaagtagctc ctatatgaaa aatagaggtc tttccattta gatagtagtg gaaagacctc
     1561 tatttatctt ttgaaagtga atacaaaaat aaagcacact ctgctataat ataggtgatt
     1621 aatccatttg agagaggtgc tttatcatgt atcaaaatta taccataaac caactttgtt
     1681 tgcctataga tcttgaaatt aaattagaag aaaatgattt tgctcatgcc attgtgcagt
     1741 ttgttgactc tattcccgat gaagtctttc ttccttatta tcaatctatg ggtagacccc
     1801 aatatcatcc tcgtatgcta ctttccatta ttctttgtgc ctatattcaa ggggtttatt
     1861 cgggccgcca aatacaaaat atgctgatag atagtattcg gatgcgctac ttatctcaag
     1921 agcaattccc taactttcgt actattaatc gttttcgcgt tcatccgatt atgaacgata
     1981 ttctagatca ttcatttgtt caatttcgtg agctactggt tcaaagtggc ttaatcagtg
     2041 gcagtgctct atacattgat ggtacaaaaa ttgaagcgga tgcgaataaa tactctttcg
     2101 tttggaaaaa aagtatttta aagtataagg atagccttga tcaaaaagcc cttgaaaact
     2161 accaacaaat ggtggaaaca aaaatcttac ctgagttaat agatgattta aaggatgaac
     2221 tttctataga agagattgaa aggattcgtc aatctttgga agaaaaggaa aatcaattaa
     2281 ttgaagcgat tgaccaaacc gaaacagtag aagggggctg acccattatt aataaggagt
     2341 ggacaacatg attgatgtaa atgagctatt ggaagaagct attagagaaa ctgaaaatct
     2401 aaatgatggc gaagtttttc ttgttaaaga tttattcaag ggatatgtgg ggaataggat
     2461 acccagaaag gatcgacttc tgcttggaac gttattttta aaccatgtta gcaaaatgaa
     2521 tggtaattta aaggctattg aaaagacttc atctaatcag cagaggtata aaaagacaat
     2581 tgataagttt taactatctt ttgtgaaatt aaaaaaatta taaatatgtt gagtagaagc
     2641 aaaagatttg gcttggaatt tttacagcag tgaatcgata aaaggagcat gcttgatggt
     2701 agataatatt attaaatcag tagcagagaa attatcctct ctgtcttata tagaaggtat
     2761 tgttttaggt ggttcacgtg caaggggcac ccatacagag gattcggata tagatatcgg
     2821 catctattac aattcagaat catttgacat aaatactatt aatcaattcg ctacaaagct
     2881 ggatgatgag catagaaata accttgttgt acctcccgga gcatggggtg attggattaa
     2941 tggcggcgga tggttagtca taaacgggta tcatgtggat ttaattttac gtgatattaa
     3001 acgtgtggaa caaataatga aagatacaga gcacggaatt gttactgcca attatcagac
     3061 tgggcatccc catggttata ttagtgcaat gtatcgagga gaattagcga ttagcaaaat
     3121 actatatgct aagaatgaaa gcttatgcga attaaaaaaa caggcagaaa cttatcccaa
     3181 tgctttgcag aaaagtttag ttaacttttt tatgtttgaa gcagggttct ctttaatgtt
     3241 tgtaaaagca aattcgggaa cagacgataa atattatatt gcgggtcatg tttttcgtat
     3301 agtttcatgt ttaaatcaag tgttatttgc atgtaataat gcttattgta tcaacgaaaa
     3361 gaaagctata aaactgcttg aaacttttga acataaacct gaaaaatata ccgagaaggt
     3421 aaatcatatt tttgaagtac tcggtatctc actttttgaa tgctacgaca tgaccgagaa
     3481 gctttataat gaagtgaatg aaattgtatc ggagataaat aactttttaa acgaggagag
     3541 ttcagatgaa agaaaacaaa tatgatgata atatattttt tcaaaaatac agtcaaatga
     3601 gtcgctcgca gaaaggactg gctggtgcgg gagaatggga gactttgaaa aagatgctac
     3661 ctgattttaa gggtaagcgt gtgcttgatt taggatgcgg ctatggatgg cactgtatat
     3721 atgcgatgga aaacggtgct tcctctgtag taggtgttga tatttctcat aaaatgctcg
     3781 aagtagcaaa aggaaaaacc cattttccac agattgaata tgaatgctgt gccatagaag
     3841 atgtggattt cccagaggag agctttgatg taatactaag ttcgcttgcg tttcattatg
     3901 tagcagacta tgagaattta ataaaaaaga tatataggat gctgaaggct ggtggcaatt
     3961 tagtttttac agttgaacat cctgttttta ctgctcatgg aacacaagac tggtattata
     4021 acgaaaaagg agaaatactg catttcccgg tggacaatta ttattatgag ggcaaacgga
     4081 cagctatgtt tttggaagaa aaggttacaa aatatcatag aacactgacc acatatctaa
     4141 atacactgct ttcaaatagt tttataataa atcagattgt ggagccacag ccgccagaga
     4201 acatgatgga tattccgggg atggcggatg aaatgcgacg cccaatgatg ctgattgtat
     4261 cggcaaaaaa gaagatgtaa taatatagaa aaaataaacg aggagtatgt aaatgagatc
     4321 agaaaaagaa atgatggatt tagtactttc tttagcagaa caggatgaac gtattcgaat
     4381 tgtgaccctt gaggggtcac gcgcaaatat taatatacct aaagatgaat ttcaggatta
     4441 tgatattaca tattttgtaa gtgatataga acctagaacc gtttatatct aatgatgact
     4501 ggcttaatca atttgggaat ataataatga tgcaaaagcc ggaggatatg gaattattcc
     4561 cacctgaaga aaagggattt tcctatctta tgctatttga tgattacaat aaaattgatc
     4621 ttaccttatt gcccttggaa gagttagata attacctaaa gggcgataaa ttaataaagg
     4681 ttctaattga taaagattgt agaattaaaa gggacatagt tccgactgat atagattatc
     4741 atgtaagaaa gccaagcgca agggagtatg atgattgctg caatgaattt tggaatgtaa
     4801 caccttatgt tattaaagga ttgtgccgta aggaaatttt atttgctatt gatcatttta
     4861 atcagattgt tcgccatgag ctgctgagaa tgatatcatg gaaggtcggc atcgaaacag
     4921 gctttaaatt aagtgtaggc aagaactata agtttattga aaggtatata tccgaggatt
     4981 tgtgggagaa acttttgtcc acctaccgga tggattccta tgaaaacata tgggaagcat
     5041 tatttctatg ccatcaattg ttcagggcgg tatccggtga ggtggcggaa aggcttcatt
     5101 atgcctatcc ggagtatgat aggaatataa caaaatatac cagggacatg tataaaaaat
     5161 acactggtaa aaccggctgc ctggatagca catatgccgc tgatatagaa gagaggcggg
     5221 aacagtgatt acagaaatga aagcagggca cctgaaagat atcgataaac ccagcgaacc
     5281 atttgaggtg ataggtaaga ttataccgag gtatgaaaac gagaattgga cctttacaga
     5341 attactctat gaagcgccat atttaaaaag ctaccaagac gaagaggatg aagaggatga
     5401 ggaggcagat tgccttgaat atattgacaa tactgataag ataatatatc tttactacca
     5461 agacgataaa tgcgtcggaa aagttaaact gcgaaaaaat tggaaccggt acgcttatat
     5521 agaagatatc gccgtatgta aggatttcag ggggcaaggc ataggcagcg cgcttatcaa
     5581 tatatctata gaatgggcaa agcataaaaa cttgcatgga ctaatgcttg aaacccagga
     5641 caataacctt atagcttgta aattctatca taattgtggt ttcaaaatcg gctccgtcga
     5701 tactatgtta tacgccaact ttgaaaacaa ctttgaaaaa gctgttttct ggtatttaag
     5761 gttttagaat gcaaggaaca gtgaattgga gttcgtcttg ttataattag cttcttgggg
     5821 tatctttaaa tactgtagaa aagaggaagg aaataataaa tggctaaaat gagaatatca
     5881 ccggaattga aaaaactgat cgaaaaatac cgctgcgtaa aagatacgga aggaatgtct
     5941 cctgctaagg tatataagct ggtgggagaa aatgaaaacc tatatttaaa aatgacggac
     6001 agccggtata aagggaccac ctatgatgtg gaacgggaaa aggacatgat gctatggctg
     6061 gaaggaaagc tgcctgttcc aaaggtcctg cactttgaac ggcatgatgg ctggagcaat
     6121 ctgctcatga gtgaggccga tggcgtcctt tgctcggaag agtatgaaga tgaacaaagc
     6181 cctgaaaaga ttatcgagct gtatgcggag tgcatcaggc tctttcactc catcgacata
     6241 tcggattgtc cctatacgaa tagcttagac agccgattag ccgaattgga ttacttactg
     6301 aataacgatc tggccgatgt ggattgcgaa aactgggaag aagacactcc atttaaagat
     6361 ccgcgcgagc tgtatgattt tttaaagacg gaaaagcccg aagaggaact tgtcttttcc
     6421 cacggcgacc tgggagacag caacatcttt gtgaaagatg gcaaagtaag tggctttatt
     6481 gatcttggga gaagcggcag ggcggacaag tggtatgaca ttgccttctg cgtccggtcg
     6541 atcagggagg atatcgggga agaacagtat gtcgagctat tttttgactt actggggatc
     6601 aagcctgatt gggagaaaat aaaatattat attttactgg atgaattgtt ttagtaccta
     6661 gatttagatg tctaaaaagc tt
//
LOCUS       DACBZK010000324         6470 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.guided.110, whole genome shotgun sequence.
ACCESSION   DACBZK010000324 DACBZK010000000
VERSION     DACBZK010000324.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.guided.110"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            104..1072
                     /locus_tag="IVD66_003149"
     CDS             104..1072
                     /locus_tag="IVD66_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HAP6147267.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1065..2096
                     /gene="vanA"
                     /locus_tag="IVD66_003150"
     CDS             1065..2096
                     /gene="vanA"
                     /locus_tag="IVD66_003150"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HAP6147268.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPTRSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2102..2710
                     /locus_tag="IVD66_003151"
     CDS             2102..2710
                     /locus_tag="IVD66_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HAP6147269.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            3138..4049
                     /gene="vanY"
                     /locus_tag="IVD66_003152"
     CDS             3138..4049
                     /gene="vanY"
                     /locus_tag="IVD66_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HAP6147270.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            4202..4687
                     /gene="vanZ"
                     /locus_tag="IVD66_003153"
     CDS             4202..4687
                     /gene="vanZ"
                     /locus_tag="IVD66_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HAP6147271.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(4974..5303)
                     /locus_tag="IVD66_003154"
     CDS             complement(4974..5303)
                     /locus_tag="IVD66_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6147272.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            5608..5937
                     /locus_tag="IVD66_003155"
     CDS             5608..5937
                     /locus_tag="IVD66_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007723369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP6147273.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            5927..6214
                     /locus_tag="IVD66_003156"
     CDS             5927..6214
                     /locus_tag="IVD66_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP6147274.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
BASE COUNT         2135 a         1072 c         1348 g         1915 t
ORIGIN      
        1 gtaagaacga gccgttttcg ttcttcagag aaagatttga caagattacc attggcatcc
       61 ccgttttatt tggtgccttt cacagaaagg gttggtctta attatgaata acatcggcat
      121 tactgtttat ggatgtgagc aggatgaggc agatgcattc catgctcttt cgcctcgctt
      181 tggcgttatg gcaacgataa ttaacgccaa cgtgtcggaa tccaacgcca aatccgcgcc
      241 tttcaatcaa tgtatcagtg tgggacataa atcagagatt tccgcctcta ttcttcttgc
      301 gctgaagaga gccggtgtga aatatatttc tacccgaagc atcggctgca atcatataga
      361 tacaactgct gctaagagaa tgggcatcac tgtcgacaat gtggcgtact cgccggatag
      421 cgttgccgat tatactatga tgctaattct tatggcagta cgcaacgtaa aatcgattgt
      481 gcgctctgtg gaaaaacatg atttcaggtt ggacagcgac cgtggcaagg tactcagcga
      541 catgacagtt ggtgtggtgg gaacgggcca gataggcaaa gcggttattg agcggctgcg
      601 aggatttgga tgtaaagtgt tggcttatag tcgcagccga agtatagagg taaactatgt
      661 accgtttgat gagttgctgc aaaatagcga tatcgttacg cttcatgtgc cgctcaatac
      721 ggatacgcac tatattatca gccacgaaca aatacagaga atgaagcaag gagcatttct
      781 tatcaatact gggcgcggtc cacttgtaga tacctatgag ttggttaaag cattagaaaa
      841 cgggaaactg ggcggtgccg cattggatgt attggaagga gaggaagagt ttttctactc
      901 tgattgcacc caaaaaccaa ttgataatca atttttactt aaacttcaaa gaatgcctaa
      961 cgtgataatc acaccgcata cggcctatta taccgagcaa gcgttgcgtg ataccgttga
     1021 aaaaaccatt aaaaactgtt tggattttga aaggagacag gagcatgaat agaataaaag
     1081 ttgcaatact gtttgggggt tgctcagagg agcatgacgt atcggtaaaa tctgcaatag
     1141 agatagccgc taacattaat aaagaaaaat acgagccgtt atacattgga attacgaaat
     1201 ctggtgtatg gaaaatgtgc gaaaaacctt gcgcggaatg ggaaaacgac aattgctatt
     1261 cagctgtact ctcgccggat aaaaaaatgc acggattact tgttaaaaag aaccatgaat
     1321 atgaaatcaa ccatgttgat gtagcatttt cagctttgca tggcaagtca ggtgaagatg
     1381 gatccataca aggtctgttt gaattgtccg gtatcccttt tgtaggctgc gatattcaaa
     1441 gctcagcaat ttgtatggac aaatcgttga catacatcgt tgcgaaaaat gctgggatag
     1501 ctactcccgc cttttgggtt attaataaag atgataggcc ggtggcagct acgtttacct
     1561 atcctgtttt tgttaagccg acgcgttcag gctcatcctt cggtgtgaaa aaagtcaata
     1621 gcgcggacga attggactac gcaattgaat cggcaagaca atatgacagc aaaatcttaa
     1681 ttgagcaggc tgtttcgggc tgtgaggtcg gttgtgcggt attgggaaac agtgccgcgt
     1741 tagctgttgg cgaggtggac caaatcaggc tgcagtacgg aatctttcgt attcatcagg
     1801 aagtcgagcc ggaaaaaggc tctgaaaacg cagttataac cgttcccgca gacctttcag
     1861 cagaggagcg aggacggata caggaaacgg caaaaaaaat atataaagcg ctcggctgta
     1921 gaggtctagc ccgtgtggat atgtttttac aagataacgg ccgcattgta ctgaacgaag
     1981 tcaatactct gcccggtttc acgtcataca gtcgttatcc ccgtatgatg gccgctgcag
     2041 gtattgcact tcccgaactg attgaccgct tgatcgtatt agcgttaaag gggtgataag
     2101 catggaaata ggatttactt ttttagatga aatagtacac ggtgttcgtt gggacgctaa
     2161 atatgccact tgggataatt tcaccggaaa accggttgac ggttatgaag taaatcgcat
     2221 tgtagggaca tacgagttgg ctgaatcgct tttgaaggca aaagaactgg ctgctaccca
     2281 agggtacgga ttgcttctat gggacggtta ccgtcctaat cgtgctgtaa actgttttat
     2341 gcaatgggct gcacagccgg aaaataacct gacaaaggaa agttattatc ccaatattga
     2401 ccgaactgag atgatttcaa aaggatacgt ggcttcaaaa tcaagccata gccgcggcag
     2461 tgccattgat cttacgcttt atcgattaga cacgggtgag cttgtaccaa tggggagccg
     2521 atttgatttt atggatgaac gctctcatca tgcggcaaat ggaatatcat gcaatgaagc
     2581 gcaaaatcgc agacgtttgc gctccatcat ggaaaacagt gggtttgaag catatagcct
     2641 cgaatggtgg cactatgtat taagagacga accatacccc aatagctatt ttgatttccc
     2701 cgttaaataa acttttaacc gttgcacgga caaactatat aagctaactc tttcggcagg
     2761 aaacccgacg tatgtaactg gttcttaggg aatttatata tagtagatag tattgaagat
     2821 gtaaggcaga gcgatattgc ggtcattatc tgcgtgcgct gcggcaagat agcctgataa
     2881 taagactgat cgcatagagg ggtggtattt cacaccgccc attgtcaaca ggcagttcag
     2941 cctcgttaaa ttcagcatgg gtatcactta tgaaaattca tctacattgg tgataatagt
     3001 aaatccagta gggcgaaata attgactgta atttacgggg caaaacggca caatctcaaa
     3061 cgagattgtg ccgtttaagg ggaagattct agaaatattt catacttcca actatatagt
     3121 taaggaggag actgaaaatg aagaagttgt tttttttatt gttattgtta ttcttaatat
     3181 acttaggtta tgactacgtt aatgaagcac tgttttctca ggaaaaagtc gaatttcaaa
     3241 attatgatca aaatcccaaa gaacatttag aaaatagtgg gacttctgaa aatacccaag
     3301 agaaaacaat tacagaagaa caggtttatc aaggaaatct gctattaatc aatagtaaat
     3361 atcctgttcg ccaagaaagt gtgaagtcag atatcgtgaa tttatctaaa catgacgaat
     3421 taataaatgg atacgggttg cttgatagta atatttatat gtcaaaagaa atagcacaaa
     3481 aattttcaga gatggtcaat gatgctgtaa agggtggcgt tagtcatttt attattaata
     3541 gtggctatcg agactttgat gagcaaagtg tgctttacca agaaatgggg gctgagtatg
     3601 ccttaccagc aggttatagt gagcataatt caggtttatc actagatgta ggatcaagct
     3661 tgacgaaaat ggaacgagcc cctgaaggaa agtggataga agaaaatgct tggaaatacg
     3721 ggttcatttt acgttatcca gaggacaaaa cagagttaac aggaattcaa tatgaactat
     3781 ggcatattcg ctatgttggt ttaccacata gtgcgattat gaaagaaaag aatttcgttc
     3841 tcgaggaata tatggattac ctaaaagaag aaaaaaccat ttctgttagt gtaaatgggg
     3901 aaaaatatga gatcttttat tatcctgtta ctaaaaatac caccattcat gtgccgacta
     3961 atcttcgtta tgagatatca ggaaacaata tagacggtgt aattgtgaca gtgtttcccg
     4021 gatcaacaca tactaattca aggaggtaag gatggcggaa tgaaaccaac gaaattaatg
     4081 aacagcatta ttgtactagc acttttgggg taacgttagc tttttaattt aaaacccacg
     4141 ttaactagga cattgctata ctaatgatac aacttaaaca aaagaattag aggaaattat
     4201 attgggaaaa atattatcta gaggattgct agctttatat ttagtgacac taatctggtt
     4261 agtgttattc aaattacaat acaatatttt atcagtattt aattatcatc aaagaagtct
     4321 taacttgact ccatttactg ctactgggaa tttcagagag atgatagata atgttataat
     4381 ctttattcca tttggcttgc ttttgaatgt caattttaaa gaaatcggat ttttacctaa
     4441 gtttgctttt gtactggttt taagtcttac ttttgaaata attcaattta tcttcgctat
     4501 tggagcgaca gacataacag atgtaattac aaatactgtt ggaggctttc ttggactgaa
     4561 attatatggt ttaagcaata agcatatgaa tcaaaaaaaa ttagacagag ttattatttt
     4621 tgtaggtata cttttgctcg tattattgct cgtttaccgt acccatttaa gaataaatta
     4681 cgtgtaagat gtctaaatca agcaatctga tctttcatac acataaagat attgaatgaa
     4741 ttggattaga tggaaaacgg gatgtgggga aactcgcccg taggtgtgaa gtgaggggaa
     4801 aaccggtgat aaagtaaaaa gcttacctaa cactatagta acaaagaaag cccaattatc
     4861 aattttagtg ctgaggaatt ggtctcttta ataaatttcc ttaacgttgt aaatccgcat
     4921 tttcctgacg gtacccccaa actaagattt catagataga ttttctgata actttaaaaa
     4981 acacgaatag cggaaaggat gtcttcattc gctaaagagt aataaactac ttttccatct
     5041 tgacgtgatt ttgccattcc atgttttttt aaaaaacgta aatggtgtga cgttgtagcg
     5101 acactagcag taagtatttc tgctaaatca cagacgcaca tttccttata ggtttctaaa
     5161 gcatagaaaa ttttaattct agaaaaatcg ctgaaacatt tccctaacac aagtaagttt
     5221 gaaaaatctt tttgatccaa tttatttttt attccattta ctttttcttt atgtacgaca
     5281 gtcacttggc aaactttttt cattcatctc acctcacatt caaacgatta tttgaatgaa
     5341 gtatacctat ttgatcactc ttttgtcaat ctaccttaat tccaatacac tattataagc
     5401 aatttcatgt attgaagtaa acttacttgc aagtgcgttt ttgattccaa gttaaaaaca
     5461 tattattatt ctacataatt tcctaatcaa ataaaactcc tttgaaaatt gttctaaagg
     5521 agttttatta ttttgtattt ctactaaaaa tagcgtacaa tgtaattact aagtaattac
     5581 gaaatgtaaa ataatggagg aaataatatg attacaaaaa caagaaaaca aggaaattct
     5641 attatgttaa cggtccctaa agaattcgat gtgcccaatg gtgttgaagt agaagctaag
     5701 cttgtagaga atggtatcct ttatgagttt gtagagccta aaaaagaatt ttttgatttt
     5761 agtgaagata ttttggctga tattctttca gaaggttata gcaaacaaga gatcttaaaa
     5821 gaatttagaa atagaaaaaa tgcgttaact tctgcattta aatctattgc tgaagatact
     5881 gttgcaaatt ctaaaccgat gacaaaagag gagttggcag cagaaattgg cttatgagat
     5941 tctaccttct aaacacgtaa taaagtatct aaaaaaatta aaagagaaaa cattaaaaga
     6001 acaattttta acgataattt atgatgagat agcagttcgt cctcattcgg gagaacaaaa
     6061 aacgggtgat ttatcaggaa tttgggctat tggattcaag tatgcaggta cgacatatcg
     6121 cgttgcatat gaaattaaag ataatgcagt gatacctatc ttactatgtg gaacgcatga
     6181 aaatttttat gaacaattaa aaaagattag gtaagaaccc aatgtttcaa cttgagagga
     6241 tagacgacac tttaaaagat aatttttaac agctgagagt tgtaataccc tataatttta
     6301 aaccactaac ctatatattt atgaaaaata gaaaaaatta aaacgcattt taagcctctt
     6361 tcaaattaaa agcttcatcc ttatgcacaa agagggctta aaatgcgtta ttttatattg
     6421 ttttttagta acgccgattg taaaattaag ctagacaact aaaaaagtca
//
LOCUS       DACBZK010000325         4058 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.guided.149, whole genome shotgun sequence.
ACCESSION   DACBZK010000325 DACBZK010000000
VERSION     DACBZK010000325.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.guided.149"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            42..989
                     /locus_tag="IVD66_003157"
     CDS             42..989
                     /locus_tag="IVD66_003157"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAP6147275.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            1009..1536
                     /locus_tag="IVD66_003158"
     CDS             1009..1536
                     /locus_tag="IVD66_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP6147276.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(1599..2252)
                     /locus_tag="IVD66_003159"
     CDS             complement(1599..2252)
                     /locus_tag="IVD66_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAP6147277.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            2384..3226
                     /locus_tag="IVD66_003160"
     CDS             2384..3226
                     /locus_tag="IVD66_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP6147278.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            3384..>4058
                     /locus_tag="IVD66_003161"
     CDS             3384..>4058
                     /locus_tag="IVD66_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP6147279.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPIND"
BASE COUNT         1451 a          729 c          812 g         1066 t
ORIGIN      
        1 aaaactatta gacaaatgat attttacgag gaggaaaaag gatggaacaa gcgtatcttg
       61 acttaggaag aaaattgttg gaagaagggc atcgtaaaga agacagaaca ggcacaggca
      121 cattaagctt attcggatac caaatgcggt ttgatctgca aaaagggttt cctttgttaa
      181 caacgaaacg agtacctttt ggattgatca aaagcgaatt gctttggttt ttaaaaggag
      241 atacgaatat ccgctatcta ttacaaaata aaaaccatat ttgggatgaa tgggcatttg
      301 aacgctacat caaaagtcca gactataatg gaccagatat gactgatttt ggccatagat
      361 gtttgacaga tcctgaattc aatgaagaat ataaaaagca gagcaagctt ttttgcgaga
      421 agatcctaac cgatgattcc tttgctgaaa catacggcga tcttggacac atctacggct
      481 atcaatggcg tcactgggaa acaaaagacg gtggctttat cgatcaaatc aaacaagtga
      541 tcgaagcaat caaaaagact cctgattcta gaagattgat cgtttctgca tggaatccgg
      601 aagatgttcc tagcatggct ttgcctcctt gtcatacgat gtttcaattt tatgttcaag
      661 agggacggct aagctgccaa ttgtatcaac gcagtgggga tgtgtttcta ggcgttccgt
      721 tcaacattgc aagttatgcg ttgctgactc acctaattgc acatgaaaca ggtttagcgg
      781 ttggcgaatt tgttcacaca ttaggagatg ctcatcttta tatcaatcat atcgaacaaa
      841 tgaaagaaca attgagccga gaaatacgcg catttccgac tttagttttg aatcaggaaa
      901 agcagtcagt atttgatttt gagatggaag atatccaatt agaaggatat gacccacatc
      961 cggcgatcaa agctcctatc gctgtttaga atcagaaagg atgagaaaat gttagctgca
     1021 atttgggcac aggatgaaaa cggattgatt ggaaaagaag accgtcttcc ttggcgtttg
     1081 ccaaatgatc tgaaattctt caaacaaatg acagaagcaa atacactagt gatgggacga
     1141 aaaacattcg aagggatggg tagccgtccg ttgccgaatc gtcagacgat tgttttgacg
     1201 agagattctt cctataaagc agaaggcgtg catgtcatgc atagtgtgga agacgtgctt
     1261 gctctggaaa aagaaacaga cggtatcttt ttcatcgctg gagggtcagc tgtttatcaa
     1321 gaatttctgc cattttgtac gatattatac cgtacagtca tccatcatgt attcgatgga
     1381 gatgcttatt ttccacctgt tgactggtct gattggtcac tgatcaatac tagtcaagga
     1441 gaaatggatg aaaaaaatcg ttatccgcat caatttgaaa cgtatcagcg taatgagaat
     1501 cctgtaaaaa gcgggacagg cgaattgacg atataaaaaa gctatggata gactagctgt
     1561 tatttagagc tgtcccatcc atagctttat tttttttatt aagtaaagaa taaaacagag
     1621 aagtacataa aacctgcacc taacataaca aacaaatgcc aaacaacatg catatagcgg
     1681 atagaattca agctataaaa gaatgcgcct atcgtgtaag aaagcccgcc tgctaccatc
     1741 aaaataacac cagtcattcc aagagagtga taaagaggaa cagcagccac gacacagagc
     1801 caccccataa aaatatagat gatcgtagat acttttgata ctctctcccg tttatgcaac
     1861 gtcaacgctt tatatataat gccaagaatc gcaaacaacc agattaatac aaataaagtc
     1921 caacctagcc atcctcggat actcagcaaa caaaaaggag tataacttcc tgcaatcaaa
     1981 agaaaaatcg aactatgatc gaatacttgg aacacctttt ttgcttttgt aaaaatcaat
     2041 gaatgaaaca aagtagacgt taaaaataaa agaatcatca tcgatccata gatagcataa
     2101 gagacaatat ggagggagga atgcaagtgg gcacctttta ctaaaagaac cactagtccc
     2161 gcgatactca atccagtccc aattccatgg gtgactgcat taaacacttc atttaatatt
     2221 tcatacgttc gattaaattt cgttttttcc atgaaaacgg ctcctttact aggtgtaatt
     2281 aatgaaaaat cattatttgt ctgttatact aaaaatagaa attgtcttac atgtagttta
     2341 acatgaataa ggcatcttgt taaagaaaga gagagagaaa ataatgacaa atgtaaaaat
     2401 cgtaacagat tcttcatgta cgatggaaaa aaatgtacgc gatgctttag gcattcgtgt
     2461 catgccgcta tccatcatga tcgacggaac agtatatccc gatgatgacc aactagacgg
     2521 cgaaagattt atggaaatga tggcgaaagc aaaaaatctg cccaaaacaa gccaaccacc
     2581 aattggagaa ttcatctcga tgtatgatga gctaggagaa gacggcagtg aagtgatttc
     2641 gatccatatg acaaaaggct tgagtggaac agtagaagca gcaagacaag ccagtaatct
     2701 aacaaaaacg aaagtaacgg ttatcgacag tgataccact gaccaaggat tatcttttca
     2761 ggtaattcga gcagctgaat tagcaaaaga aggtaaaaca gtagagaaaa tccttgaaga
     2821 agtcaaaaaa gtacaagaca atacaaaatt atacatcgga atatccacac tagataactt
     2881 ggtaaaaggt ggaagaatca gccgaacaac tggtttgctg tctagtgttt tgaacatacg
     2941 cgtggtgatg aatttcgccc attctgaatt aatccctgta actaaggggc gaggaaagaa
     3001 aacgttcgat aaatggttta ataatttgaa aaatgaactg aaagaattgc caaatgtgcg
     3061 acaaatcggt atttcacatg cggatgcaaa agaattggcg caagaattca aagagggttt
     3121 gcaagaatta ttcccggaca tgcatatccc tgtactgcat acgaatccgg ttatcgctac
     3181 gcatactggt aaagacgcgt ttgcaatcat gtattatgta gattagtcga aaagaggata
     3241 agccctcagc ctgaaaggct tgcagcttat tctctttttc tttataaaat taggaaaata
     3301 attgttttct tttttcataa agactacctt tttgataaaa tttttgataa cattagaacc
     3361 aatcgaatac aagaggtgaa aaaatgaaat taacgaaacg acatttgatc ctcgttttgt
     3421 tcccattatt aattgcgatc atcatctatg caggtttagc tgcttctata ccgaaagctg
     3481 gcccactaat gaaaccagta actactgtga gagaagatcc aaataaaaaa gaaaaacttc
     3541 actacatagc tatcggagat tcgctgactg aaggagtagg agatcaaacc aagcaaggag
     3601 gattcgttcc ccttgtcgca aatgatctaa aagaccgtta taatttgacc gcggttgaaa
     3661 cagaaaacta tggtgtaaat ggtgaacgaa gtgaccagat cttaaagcga gtaaaaacaa
     3721 aagaagaaat tcgaaacaat atcaaaacag ctgattttat cacactgact gttggcggta
     3781 atgatttgat gaaagttatc caaaataatt tattcgggtt aacggtcaat tcctttaaaa
     3841 agccactgaa aaactatcag gaaaatgtca cagaactatt ggaagaattt cgatccctca
     3901 ataaaaccgc acctatttac attttaggca tctacaatcc attttatttg aactttcctg
     3961 agatcactga catgcagaca attgttaaca attggaacaa aggaacagaa acggtgacaa
     4021 aaaaaatgcc gaactgctac tttatcccaa tcaatgat
//
LOCUS       DACBZK010000326         2791 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.guided.171, whole genome shotgun sequence.
ACCESSION   DACBZK010000326 DACBZK010000000
VERSION     DACBZK010000326.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.guided.171"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..1348
                     /locus_tag="IVD66_003162"
                     /note="aph(2'')-Ia"
     CDS             <1..1348
                     /locus_tag="IVD66_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HAP6147280.1"
                     /translation="DFILYLKLCNRTESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQI
                     YKMYDELYTDYHYPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAV
                     ILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKY
                     LIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNT
                     NLETNVKIPNIEYSYISDELSILGYKEIKGLFLTPEIYSTMSEEEQNLLKRDIASFLR
                     QMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFE
                     GKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGE
                     DILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1478..2650)
                     /locus_tag="IVD66_003163"
     CDS             complement(1478..2650)
                     /locus_tag="IVD66_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015077585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HAP6147281.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          981 a          348 c          484 g          978 t
ORIGIN      
        1 ggattttatt ctttatttaa aactttgcaa cagaaccgaa tcattaaaaa aacattatac
       61 agagccttgg gaagatgaag tttttagagt aattattgaa tataacaatg ttcctattgg
      121 atatggacaa atatataaaa tgtatgatga gttatatact gattatcatt atccaaaaac
      181 tgatgagata gtctatggta tggatcaatt tataggagag ccaaattatt ggagtaaagg
      241 aattggtaca agatatatta aattgatttt tgaatttttg aaaaaagaaa gaaatgctaa
      301 tgcagttatt ttagaccctc ataaaaataa tccaagagca ataagggcat accaaaaatc
      361 tggttttaga attattgaag atttgccaga acatgaatta cacgagggca aaaaagaaga
      421 ttgttattta atggaatata gatatgatga taatgccaca aatgttaagg caatgaaata
      481 tttaattgag cattactttg ataatttcaa agtagatagt attgaaataa tcggtagtgg
      541 ttatgatagt gtggcatatt tagttaataa tgaatacatt tttaaaacaa aatttagtac
      601 taataagaaa aaaggttatg caaaagaaaa agcaatatat aattttttaa atacaaattt
      661 agaaactaat gtaaaaattc ctaatattga atattcgtat attagtgatg aattatctat
      721 actaggttat aaagaaatta aaggactttt tttaacacca gaaatttatt ctactatgtc
      781 agaagaagaa caaaatttgt taaaacgaga tattgccagt tttttaagac aaatgcacgg
      841 tttagattat acagatatta gtgaatgtac tattgataat aaacaaaatg tattagaaga
      901 gtatatattg ttgcgtgaaa ctatttataa tgatttaact gatatagaaa aagattatat
      961 agaaagtttt atggaaagac taaatgcaac aacagttttt gagggtaaaa agtgtttatg
     1021 ccataatgat tttagttgta atcatctatt gttagatggc aataatagat taactggaat
     1081 aattgatttt ggagattctg gaattataga tgaatattgt gattttatat acttacttga
     1141 agatagtgaa gaagaaatag gaacaaattt tggagaagat atattaagaa tgtatggaaa
     1201 tatagatatt gagaaagcaa aagaatatca agatatagtt gaagaatatt atcctattga
     1261 aactattgtt tatggaatta aaaatattaa acaggaattt atcgaaaatg gtagaaaaga
     1321 aatttataaa aggacttata aagattgatt atataatata tgaaaagcta ttataaaaga
     1381 cattagtatt aaatagttta aaaaaatgaa aaataataaa ggaagtgagt caagtccaga
     1441 ctcctgtgta aaatgctata caatgttttt accatttcta cttatcaaaa ttgatgtatt
     1501 ttcttgaaga ataaatccat tcatcatgta ggtccataag aacggctcca attaagcgat
     1561 tggctgatgt ttgattgggg aagatgcgaa taatcttttc tcttctgcgt acttcttgat
     1621 tcagtcgttc aattagattg gtactcttta gtcgattgtg ggaatttcct tgtacggtat
     1681 attgaaaggc gtcttcgaat ccatcatcca atgatgcgca agcttttgaa tattttggtt
     1741 gatcgatata atcatgaatc aatcgatttt tagcctcacg cgctaagtta atatctgtga
     1801 acttaaaaat tcctttaaca gcttctctga aagattttga atttttttta ggaatggtgg
     1861 taaagatatt tcttaggaag tgaacttggc atctttgcca acttacgttg gtgaaggatt
     1921 ttctaatggc agagactaat cctttgtgcg catcagaaat aacgagttcc gtaccttgta
     1981 aaccgcgttc ttttaggtat tcaaaaaatg ttgtccaggt ctcttcgctt tcgccacttt
     2041 gaatcatgaa gccgataatt tcacggtcgc catctttggt tattccaatc gctatatgac
     2101 agctttttga gagtactcga ttttcttctc gtacttttat atagagtaca tcggtcatta
     2161 agtaaggata atttttttct gataataaac gattctgcca ctcgttaacc ataggttcta
     2221 gctgttctgt taagctagaa acgaaggact tagagacgga tttaccacaa agttcttcca
     2281 caatttttga tactttacga gttgaaacgc ctgatacata catttccaac attgaagcca
     2341 tgagggcttt ttcgtttcgt tgataacgtt caaacactgt gggtgaaaaa tggccatcac
     2401 gtgttctggg tacttttaat tctagcgtgc ctacacgtgt cgtaaagctg cgctcataat
     2461 agccatttcg ttgactttgt cggttttctg ttcgttcata ttcttttgct tgaatatatt
     2521 ctgttcgttg attttccatt agttgattaa ataccgttgt taaaatattt ttagaaacgt
     2581 catcctttac agaatattca ataatgcttt gaatctcttc gcttttcagt gtaaaatgta
     2641 cttgggtcat gtaaaagtcc tcctgggtat gtttttgtcg ttaaaaacat tgtaccgtaa
     2701 aaggactgtt atatggcctt tttactttta cacaattata cggactttat caataatagc
     2761 tattttaata gaatttataa gttaaaatat t
//
LOCUS       DACBZK010000327         2246 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.guided.186, whole genome shotgun sequence.
ACCESSION   DACBZK010000327 DACBZK010000000
VERSION     DACBZK010000327.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.guided.186"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            <1..152
                     /locus_tag="IVD66_003164"
     CDS             <1..152
                     /locus_tag="IVD66_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016204422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6147282.1"
                     /translation="YLIVDLKLCNRTNYAVKLYKEGNMTVNQICEITNVSRASLYRKL
                     SEVNN"
     gene            366..1061
                     /gene="vanR"
                     /locus_tag="IVD66_003165"
     CDS             366..1061
                     /gene="vanR"
                     /locus_tag="IVD66_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAP6147283.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1039..2193
                     /locus_tag="IVD66_003166"
     CDS             1039..2193
                     /locus_tag="IVD66_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAP6147284.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          758 a          410 c          475 g          603 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaaccaa ttatgcggta aagctatata
       61 aagaaggaaa tatgactgta aatcaaattt gtgaaattac taatgtatct agggcttcat
      121 tatacaggaa attatcagaa gtgaataatt agccattctg tattccgcta atgggcaata
      181 tttttaaaga agaaaaggaa actataaaat attaacagcc tcctagcgat gccgaaaagc
      241 cctttgataa aaaaagaatc atcatcttaa gaaattctta gtcatttatt atgtaaatgc
      301 ttataaattc ggccctataa tctgataaat tattaagggc aaacttatgt gaaagggtga
      361 taactatgag cgataaaata cttattgtgg atgatgaaca tgaaattgcc gatttggttg
      421 aattatactt aaaaaacgag aattatacgg ttttcaaata ctataccgcc aaagaagcat
      481 tggaatgtat agacaagtct gagattgacc ttgccatatt ggacatcatg cttcccggca
      541 caagcggcct tactatctgt caaaaaataa gggacaagca cacctatccg attatcatgc
      601 tgaccgggaa agatacagag gtagataaaa ttacagggtt aacaatcggc gcggatgatt
      661 atataacgaa gccctttcgc ccactggagt taattgctcg ggtaaaggcc cagttgcgcc
      721 gatacaaaaa attcagtgga gtaaaggagc agaacgaaaa tgttatcgtc cactccggcc
      781 ttgtcattaa tgttaacacc catgagtgtt atctgaacga gaagcagtta tcccttactc
      841 ccaccgagtt ttcaatactg cgaatcctct gtgaaaacaa ggggaatgtg gttagctccg
      901 agctgctatt tcatgagata tggggcgacg aatatttcag caagagcaac aacaccatca
      961 ccgtgcatat ccggcatttg cgcgaaaaaa tgaacgacac cattgataat ccgaaatata
     1021 taaaaacggt atggggggtt ggttataaaa ttgaaaaata aaaaaaacga ctattccaaa
     1081 ctagaacgaa aactttacat gtatatcgtt gcaattgttg tggtagcaat tgtattcgtg
     1141 ttgtatattc gttcaatgat ccgagggaaa cttggggatt ggatcttaag tattttggaa
     1201 aacaaatatg acttaaatca cctggacgcg atgaaattat atcaatattc catacggaac
     1261 aatatagata tctttattta tgtggcgatt gtcattagta ttcttattct atgtcgcgtc
     1321 atgctttcaa aattcgcaaa atactttgac gagataaata ccggcattga tgtacttatt
     1381 cagaacgaag ataaacaaat tgagctttct gcggaaatgg atgttatgga acaaaagctc
     1441 aacacattaa aacggactct ggaaaagcga gagcaggatg caaagctggc cgaacaaaga
     1501 aaaaatgacg ttgttatgta cttggcgcac gatattaaaa cgccccttac atccattatc
     1561 ggttatttga gcctgcttga cgaggctcca gacatgccgg tagatcaaaa ggcaaagtat
     1621 gtgcatatca cgttggacaa agcgtatcga ctcgaacagc taatcgacga gttttttgag
     1681 attacacggt ataacctaca aacgataacg ctaacaaaaa cgcacataga cctatactat
     1741 atgctggtgc agatgaccga tgaattttat cctcagcttt ccgcacatgg aaaacaggcg
     1801 gttattcacg cccccgagga tctgaccgtg tccggcgacc ctgataaact cgcgagagtc
     1861 tttaacaaca ttttgaaaaa cgccgctgca tacagtgagg ataacagcat cattgacatt
     1921 accgcgggcc tctccgggga tgtggtgtca atcgaattca agaacactgg aagcatccca
     1981 aaagataagc tagctgccat atttgaaaag ttctataggc tggacaatgc tcgttcttcc
     2041 gatacgggtg gcgcgggact tggattggcg attgcaaaag aaattattgt tcagcatgga
     2101 gggcagattt acgcggaaag caatgataac tatacgacgt ttagggtaga gcttccagcg
     2161 atgccagact tggttgataa aaggaggtcc taagagatgt atataatttt ggctctttgt
     2221 caaatgatgt tggtaaagag aaatct
//
LOCUS       DACBZK010000328         1290 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.guided.219, whole genome shotgun sequence.
ACCESSION   DACBZK010000328 DACBZK010000000
VERSION     DACBZK010000328.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.guided.219"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            574..1122
                     /gene="aac(6')"
                     /locus_tag="IVD66_003167"
     CDS             574..1122
                     /gene="aac(6')"
                     /locus_tag="IVD66_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAP6147285.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          456 a          188 c          257 g          389 t
ORIGIN      
        1 ctaaaattta tatcttgact tattaccatt aggctttctt cgttgaaacg ggttaaaatt
       61 ttaaagagtg atcgatctga ctgcggctgt agatggagta gaggtgaacc taagacagga
      121 taagtgatga ataaggtggc atgaacacct tgaaatcatc aataagtatc ctaaaaacga
      181 acaagtacaa aaacattgaa aacgacaata atgaattttt gttcctctta gtatttctac
      241 cgattccctt tgcttttttg taattatcta aaaattctaa aaattaagat tattatatga
      301 aaacaggttt tatttgtcaa ttcataattg gtttttttta aagcaaaaga taatctatat
      361 catgatgaac aaacagagtt ttttcctcca attgatggct ttcctgatct ttcctatttt
      421 gaataaagtg tttctgtata atttttttat tttataagta agataaataa tgaaagaata
      481 gagatactga ttggtagcta aagatttttg agcgagaaca tttcgttttt tcaaaaggac
      541 tgttagaata agcaagaaca agggggaaga cgtatgataa tcagtgaatt tgaccgtaat
      601 aatccagtat tgaaagatca gctttctgat ttactgagac tgacttggcc ggaagaatat
      661 ggagacagct cggcagaaga agtagaagaa atgatgaatc cagaacgaat cgcggtagca
      721 gcggtagacc aagatgagtt agtaggattt attggtgcaa tccctcaata cggtatcaca
      781 ggttgggaat tgcatccatt agttgtagaa agctcccgac gaaagaacca aataggtact
      841 cgattagtca attacttaga aaaagaagta gcttccagag gaggaatcac gatttattta
      901 ggtacggatg atttagacca tggaacaacg ttaagtcaaa cggacctgta tgagcataca
      961 tttgataaag tggcttccat ccagaacctt cgtgaacatc cgtatgaatt ctatgaaaaa
     1021 ttaggttata aaatcgtagg tgtcttacca aatgcaaatg gctgggacaa accggatatt
     1081 tggatggcaa aaacgattat tcctcgacca aattctcaat aataaaaaga ggttgtgaca
     1141 gaagtaatca gcttcaagaa ataagaagga atttacgaaa attacttctt gaatttttgt
     1201 gaaattccaa cttatttccg aagaagctac ttttggaaca ccgtgtacca gaggttgtga
     1261 aaaagtcgct tagtttcgag tagtaagaaa
//
LOCUS       DACBZK010000329         1236 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.guided.222, whole genome shotgun sequence.
ACCESSION   DACBZK010000329 DACBZK010000000
VERSION     DACBZK010000329.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.guided.222"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            29..1183
                     /locus_tag="IVD66_003168"
     CDS             29..1183
                     /locus_tag="IVD66_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP6147286.1"
                     /translation="MVIKKKKKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          406 a          228 c          275 g          327 t
ORIGIN      
        1 ccgaaatata taaaaacggt atggggggtt ggttataaaa aaaaaaaaaa aaaaaaacga
       61 ctattccaaa ctagaacgaa aactttacat gtatatcgtt gcaattgttg tggtagcaat
      121 tgtattcgtg ttgtatattc gttcaatgat ccgagggaaa cttggggatt ggatcttaag
      181 tattttggaa aacaaatatg acttaaatca cctggacgcg atgaaattat atcaatattc
      241 catacggaac aatatagata tctttattta tgtggcgatt gtcattagta ttcttattct
      301 atgtcgcgtc atgctttcaa aattcgcaaa atactttgac gagataaata ccggcattga
      361 tgtacttatt cagaacgaag ataaacaaat tgagctttct gcggaaatgg atgttatgga
      421 acaaaagctc aacacattaa aacggactct ggaaaagcga gagcaggatg caaagctggc
      481 cgaacaaaga aaaaatgacg ttgttatgta cttggcgcac gatattaaaa cgccccttac
      541 atccattatc ggttatttga gcctgcttga cgaggctcca gacatgccgg tagatcaaaa
      601 ggcaaagtat gtgcatatca cgttggacaa agcgtatcga ctcgaacagc taatcgacga
      661 gttttttgag attacacggt ataacctaca aacgataacg ctaacaaaaa cgcacataga
      721 cctatactat atgctggtgc agatgaccga tgaattttat cctcagcttt ccgcacatgg
      781 aaaacaggcg gttattcacg cccccgagga tctgaccgtg tccggcgacc ctgataaact
      841 cgcgagagtc tttaacaaca ttttgaaaaa cgccgctgca tacagtgagg ataacagcat
      901 cattgacatt accgcgggcc tctccgggga tgtggtgtca atcgaattca agaacactgg
      961 aagcatccca aaagataagc tagctgccat atttgaaaag ttctataggc tggacaatgc
     1021 tcgttcttcc gatacgggtg gcgcgggact tggattggcg attgcaaaag aaattattgt
     1081 tcagcatgga gggcagattt acgcggaaag caatgataac tatacgacgt ttagggtaga
     1141 gcttccagcg atgccagact tggttgataa aaggaggtcc taagagatgt atataatttt
     1201 ggctctttgt caaatgatgt tggtaaagag aaatct
//
LOCUS       DACBZK010000330         1214 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain EF18PII
            SAMN15598749-rid10849523.guided.224, whole genome shotgun sequence.
ACCESSION   DACBZK010000330 DACBZK010000000
VERSION     DACBZK010000330.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15598749
            Sequence Read Archive: SRR12286381
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000866092.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000866092.1
            Genome Coverage       :: 292x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/24/2020 09:27:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,168
            CDSs (total)                      :: 3,107
            Genes (coding)                    :: 3,029
            CDSs (with protein)               :: 3,029
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 31 of 78
            Pseudo Genes (incomplete)         :: 38 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 11 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1214
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15598749-rid10849523.guided.224"
                     /strain="EF18PII"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: San Diego, CA"
                     /collected_by="UCSD SBRG"
     gene            67..1161
                     /locus_tag="IVD66_003169"
     CDS             67..1161
                     /locus_tag="IVD66_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP6147287.1"
                     /translation="MYIVAIVVVAIVFVLYIRSMIRGKLGDWILSILENKYDLNHLDA
                     MKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKYFDEINTGIDVLIQNEDKQIE
                     LSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVMYLAHDIKTPLTSIIGYLSLL
                     DEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRYNLQTITLTKTHIDLYYMLVQ
                     MTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFNNILKNAAAYSEDNSIIDITA
                     GLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSSDTGGAGLGLAIAKEIIVQHG
                     GQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          394 a          225 c          272 g          323 t
ORIGIN      
        1 ggggggttgg ttataaaata aaaaaaaaaa aaaaacgact attccaaact agaacgaaaa
       61 ctttacatgt atatcgttgc aattgttgtg gtagcaattg tattcgtgtt gtatattcgt
      121 tcaatgatcc gagggaaact tggggattgg atcttaagta ttttggaaaa caaatatgac
      181 ttaaatcacc tggacgcgat gaaattatat caatattcca tacggaacaa tatagatatc
      241 tttatttatg tggcgattgt cattagtatt cttattctat gtcgcgtcat gctttcaaaa
      301 ttcgcaaaat actttgacga gataaatacc ggcattgatg tacttattca gaacgaagat
      361 aaacaaattg agctttctgc ggaaatggat gttatggaac aaaagctcaa cacattaaaa
      421 cggactctgg aaaagcgaga gcaggatgca aagctggccg aacaaagaaa aaatgacgtt
      481 gttatgtact tggcgcacga tattaaaacg ccccttacat ccattatcgg ttatttgagc
      541 ctgcttgacg aggctccaga catgccggta gatcaaaagg caaagtatgt gcatatcacg
      601 ttggacaaag cgtatcgact cgaacagcta atcgacgagt tttttgagat tacacggtat
      661 aacctacaaa cgataacgct aacaaaaacg cacatagacc tatactatat gctggtgcag
      721 atgaccgatg aattttatcc tcagctttcc gcacatggaa aacaggcggt tattcacgcc
      781 cccgaggatc tgaccgtgtc cggcgaccct gataaactcg cgagagtctt taacaacatt
      841 ttgaaaaacg ccgctgcata cagtgaggat aacagcatca ttgacattac cgcgggcctc
      901 tccggggatg tggtgtcaat cgaattcaag aacactggaa gcatcccaaa agataagcta
      961 gctgccatat ttgaaaagtt ctataggctg gacaatgctc gttcttccga tacgggtggc
     1021 gcgggacttg gattggcgat tgcaaaagaa attattgttc agcatggagg gcagatttac
     1081 gcggaaagca atgataacta tacgacgttt agggtagagc ttccagcgat gccagacttg
     1141 gttgataaaa ggaggtccta agagatgtat ataattttgg ctctttgtca aatgatgttg
     1201 gtaaagagaa atct
//
